V-SNARE coiled-coil homology domain-containing protein

Overview


Name	V-SNARE coiled-coil homology domain-containing protein
Smed ID	SMED30030734
Length (bp)	469

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of V-SNARE coiled-coil homology domain-containing protein (SMED30030734) t-SNE clustered cells

Violin plots show distribution of expression levels for V-SNARE coiled-coil homology domain-containing protein (SMED30030734) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of V-SNARE coiled-coil homology domain-containing protein (SMED30030734) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030734

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30030734	h1SMcG0006586	SmedASXL_007070	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30030734	h1SMcG0006586	dd_Smed_v4_10790_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30030734	h1SMcG0006586	dd_Smed_v4_10790_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30030734	h1SMcG0006586	dd_Smed_v4_10790_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30030734	h1SMcG0006586	dd_Smed_v6_10790_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30030734	h1SMcG0006586	OX_Smed_1.0.17522	ox_Smed_v2	PMID:24238224 Kao et al., 2013
zeta neoblast	SMED30030734	h1SMcG0006586	dd_Smed_v4_10790_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: VAMP2 (vesicle associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:12643])

HSP 1 Score: 118.242 bits (295), Expect = 1.434e-34
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N+K+
Sbjct:   27 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 95

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: VAMP2 (vesicle associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:12643])

HSP 1 Score: 118.242 bits (295), Expect = 1.870e-34
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N+K+
Sbjct:   29 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 97

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: VAMP2 (vesicle associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:12643])

HSP 1 Score: 117.472 bits (293), Expect = 2.637e-34
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N+K+
Sbjct:   27 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 95

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: AC129492.3 (novel protein)

HSP 1 Score: 117.472 bits (293), Expect = 3.300e-34
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N+K+
Sbjct:   27 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 95

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: VAMP3 (vesicle associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:12644])

HSP 1 Score: 116.701 bits (291), Expect = 3.988e-34
Identity = 53/73 (72.60%), Postives = 64/73 (87.67%), Query Frame = 2

Query:  110 TVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            T  +  N+RLQQTQ +++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:    6 TAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 78

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Match: snb-1 (Synaptobrevin-1 [Source:UniProtKB/Swiss-Prot;Acc:O02495])

HSP 1 Score: 108.997 bits (271), Expect = 1.877e-31
Identity = 50/71 (70.42%), Postives = 63/71 (88.73%), Query Frame = 2

Query:  116 PSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            P   NKRLQQTQA+++EVV IM++NV+KVLERDQKLS+LD+RADALQ GASQFE+SA  LK K+WW+N+K+
Sbjct:   17 PRPSNKRLQQTQAQVDEVVGIMKVNVEKVLERDQKLSQLDDRADALQEGASQFEKSAATLKRKYWWKNIKM 87

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Match: snb-2 (SyNaptoBrevin related [Source:UniProtKB/TrEMBL;Acc:Q19767])

HSP 1 Score: 90.8929 bits (224), Expect = 3.535e-24
Identity = 40/86 (46.51%), Postives = 62/86 (72.09%), Query Frame = 2

Query:   71 VETNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +E       PP  T  +   KR+Q  QA++NEV+D+MR NV+KV+ERD +L+ LD+RA+ LQ GASQF++S+  L+ K+WW+N+++
Sbjct:   11 LEAGNGEAQPPTGTYNT---KRMQMAQAQVNEVIDVMRNNVNKVMERDVQLNSLDHRAEVLQNGASQFQQSSRTLRQKYWWQNIRM 93

[Close]

Query:   71 VETNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +E       PP  T  +   KR+Q  QA++NEV+D+MR NV+KV+ERD +L+ LD+RA+ LQ GASQF++S+  L+ K+WW+N+++
Sbjct:   11 LEAGNGEAQPPTGTYNT---KRMQMAQAQVNEVIDVMRNNVNKVMERDVQLNSLDHRAEVLQNGASQFQQSSRTLRQKYWWQNIRM 93

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Match: vamp-7 (VAMP (Vesicle Associated Membrane Protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q95XH1])

HSP 1 Score: 52.7582 bits (125), Expect = 9.036e-9
Identity = 21/72 (29.17%), Postives = 48/72 (66.67%), Query Frame = 2

Query:  110 TVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVK 325
            T P++  +R+   + ++++V  +M  NV++++ER ++L  ++NR +AL+  A+ F+ +A R++  F  +N+K
Sbjct:  163 TFPTAQQQRMIDIRRQVDDVRQVMADNVERIMERGERLENMENRTEALRTSATSFKSTARRVQRHFCQKNLK 234

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Match: nSyb (gene:FBgn0013342 transcript:FBtr0331462)

HSP 1 Score: 107.842 bits (268), Expect = 1.320e-30
Identity = 50/69 (72.46%), Postives = 61/69 (88.41%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +  KRLQQTQA+++EVVDIMR NV+KVLERD KLSELD+RADALQ GASQFE+ AG+LK KFW +N+K+
Sbjct:   37 AAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLSELDDRADALQQGASQFEQQAGKLKRKFWLQNLKM 105

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Match: nSyb (gene:FBgn0013342 transcript:FBtr0306578)

HSP 1 Score: 107.842 bits (268), Expect = 1.914e-30
Identity = 50/69 (72.46%), Postives = 61/69 (88.41%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +  KRLQQTQA+++EVVDIMR NV+KVLERD KLSELD+RADALQ GASQFE+ AG+LK KFW +N+K+
Sbjct:   46 AAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLSELDDRADALQQGASQFEQQAGKLKRKFWLQNLKM 114

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Match: nSyb (gene:FBgn0013342 transcript:FBtr0302310)

HSP 1 Score: 107.842 bits (268), Expect = 1.914e-30
Identity = 50/69 (72.46%), Postives = 61/69 (88.41%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +  KRLQQTQA+++EVVDIMR NV+KVLERD KLSELD+RADALQ GASQFE+ AG+LK KFW +N+K+
Sbjct:   46 AAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLSELDDRADALQQGASQFEQQAGKLKRKFWLQNLKM 114

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Match: nSyb (gene:FBgn0013342 transcript:FBtr0331461)

HSP 1 Score: 109.383 bits (272), Expect = 2.519e-30
Identity = 50/69 (72.46%), Postives = 61/69 (88.41%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +  KRLQQTQA+++EVVDIMR NV+KVLERD KLSELD+RADALQ GASQFE+ AG+LK KFW +N+K+
Sbjct:   37 AAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLSELDDRADALQQGASQFEQQAGKLKRKFWLQNLKM 105

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Match: nSyb (gene:FBgn0013342 transcript:FBtr0072815)

HSP 1 Score: 108.612 bits (270), Expect = 3.251e-30
Identity = 50/66 (75.76%), Postives = 60/66 (90.91%), Query Frame = 2

Query:  131 KRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            KRLQQTQA+++EVVDIMR NV+KVLERD KLSELD+RADALQ GASQFE+ AG+LK KFW +N+K+
Sbjct:   40 KRLQQTQAQVDEVVDIMRTNVEKVLERDSKLSELDDRADALQQGASQFEQQAGKLKRKFWLQNLKM 105

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: vamp3 (vesicle-associated membrane protein 3 (cellubrevin) [Source:ZFIN;Acc:ZDB-GENE-040625-45])

HSP 1 Score: 121.324 bits (303), Expect = 4.548e-36
Identity = 59/80 (73.75%), Postives = 70/80 (87.50%), Query Frame = 2

Query:   89 PGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            PG+   A+  S  N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK KFWW+NVK+
Sbjct:    4 PGAD--ASGSSGSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKFWWKNVKM 81

[Close]

Query:   89 PGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            PG+   A+  S  N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK KFWW+NVK+
Sbjct:    4 PGAD--ASGSSGSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKFWWKNVKM 81

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: vamp1 (vesicle-associated membrane protein 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2725])

HSP 1 Score: 121.324 bits (303), Expect = 6.320e-36
Identity = 58/81 (71.60%), Postives = 69/81 (85.19%), Query Frame = 2

Query:   83 GIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVK 325
            G P  PP  T     N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N+K
Sbjct:   21 GAPAQPPNLT----SNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNMK 97

[Close]

Query:   83 GIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVK 325
            G P  PP  T     N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N+K
Sbjct:   21 GAPAQPPNLT----SNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNMK 97

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: vamp3 (vesicle-associated membrane protein 3 (cellubrevin) [Source:ZFIN;Acc:ZDB-GENE-040625-45])

HSP 1 Score: 120.939 bits (302), Expect = 6.559e-36
Identity = 59/80 (73.75%), Postives = 70/80 (87.50%), Query Frame = 2

Query:   89 PGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            PG+   A+  S  N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK KFWW+NVK+
Sbjct:    4 PGAD--ASGSSGSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKFWWKNVKM 81

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: vamp3 (vesicle associated membrane protein 3 [Source:NCBI gene;Acc:549726])

HSP 1 Score: 120.939 bits (302), Expect = 1.508e-35
Identity = 56/78 (71.79%), Postives = 67/78 (85.90%), Query Frame = 2

Query:   95 SPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +P  +     GN+RLQQTQA++NEVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:    3 APGPSATGDPGNRRLQQTQAQVNEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 80

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: vamp3 (vesicle associated membrane protein 3 [Source:NCBI gene;Acc:549726])

HSP 1 Score: 120.168 bits (300), Expect = 1.556e-35
Identity = 56/78 (71.79%), Postives = 67/78 (85.90%), Query Frame = 2

Query:   95 SPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +P  +     GN+RLQQTQA++NEVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:    3 APGPSATGDPGNRRLQQTQAQVNEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 80

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: idh1 (isocitrate dehydrogenase 1 (NADP+) [Source:Xenbase;Acc:XB-GENE-1004994])

HSP 1 Score: 119.398 bits (298), Expect = 4.263e-35
Identity = 54/71 (76.06%), Postives = 65/71 (91.55%), Query Frame = 2

Query:  116 PSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            P+S N+RL QTQA++NEVVDIMR+NVDKVL+RDQKL+ELD+RADALQAGASQFE SA +LK K+WWRN K+
Sbjct:   19 PASSNRRLLQTQAQVNEVVDIMRVNVDKVLDRDQKLAELDDRADALQAGASQFETSAAKLKRKYWWRNCKM 89

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: vamp4 (vesicle associated membrane protein 4 [Source:NCBI gene;Acc:549651])

HSP 1 Score: 59.6918 bits (143), Expect = 1.894e-11
Identity = 23/77 (29.87%), Postives = 50/77 (64.94%), Query Frame = 2

Query:  128 NKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKLNSEVTPSFHI 358
            N +++  Q +++EV+D+M+ N+ +V+ER ++L EL +++++L   A+ F   + +L+ + WWR  K+ + +   F I
Sbjct:   50 NDKIRHVQNQVDEVIDVMQENITRVIERGERLDELQDKSESLSDNATAFSSRSRQLRRQMWWRECKMKAIIALVFVI 126

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: vamp4 (vesicle associated membrane protein 4 [Source:NCBI gene;Acc:549651])

HSP 1 Score: 58.151 bits (139), Expect = 6.599e-11
Identity = 21/69 (30.43%), Postives = 47/69 (68.12%), Query Frame = 2

Query:  128 NKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKLNS 334
            N +++  Q +++EV+D+M+ N+ +V+ER ++L EL +++++L   A+ F   + +L+ + WWR  K+ +
Sbjct:   50 NDKIRHVQNQVDEVIDVMQENITRVIERGERLDELQDKSESLSDNATAFSSRSRQLRRQMWWRECKMKA 118

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Vamp3 (vesicle-associated membrane protein 3 [Source:MGI Symbol;Acc:MGI:1321389])

HSP 1 Score: 119.398 bits (298), Expect = 3.161e-35
Identity = 56/84 (66.67%), Postives = 68/84 (80.95%), Query Frame = 2

Query:   77 TNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + G+P     AT     N+RLQQTQ +++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:    2 STGVPSGSSAAT---GSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 82

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Vamp2 (vesicle-associated membrane protein 2 [Source:MGI Symbol;Acc:MGI:1313277])

HSP 1 Score: 118.242 bits (295), Expect = 9.842e-35
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N+K+
Sbjct:   27 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 95

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Vamp1 (vesicle-associated membrane protein 1 [Source:MGI Symbol;Acc:MGI:1313276])

HSP 1 Score: 117.472 bits (293), Expect = 2.524e-34
Identity = 53/69 (76.81%), Postives = 63/69 (91.30%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA++ EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:   29 TSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKM 97

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Vamp1 (vesicle-associated membrane protein 1 [Source:MGI Symbol;Acc:MGI:1313276])

HSP 1 Score: 117.087 bits (292), Expect = 3.668e-34
Identity = 53/69 (76.81%), Postives = 63/69 (91.30%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA++ EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:   29 TSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKM 97

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Vamp1 (vesicle-associated membrane protein 1 [Source:MGI Symbol;Acc:MGI:1313276])

HSP 1 Score: 116.316 bits (290), Expect = 6.075e-34
Identity = 53/69 (76.81%), Postives = 63/69 (91.30%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA++ EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:   29 TSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKM 97

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|P13701|SYB_TETCF (Synaptobrevin OS=Tetronarce californica OX=7787 PE=2 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 3.042e-35
Identity = 57/82 (69.51%), Postives = 69/82 (84.15%), Query Frame = 2

Query:   83 GIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G P  PP A   ++ N+RLQQTQA++ EVVDI+R+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:   18 GQPTGPPGAPPNTTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKM 99

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|Q27236|SYBL_SCHMA (Synaptobrevin-like protein OS=Schistosoma mansoni OX=6183 PE=2 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 9.430e-35
Identity = 56/71 (78.87%), Postives = 63/71 (88.73%), Query Frame = 2

Query:  116 PSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            P   NKRLQQTQA++NEVVDIMR+NVDKVLERD+ LSELD RADALQAGASQFE SAG+LK KFWW+N K+
Sbjct:   12 PIKTNKRLQQTQAQVNEVVDIMRVNVDKVLERDKNLSELDGRADALQAGASQFEASAGKLKRKFWWKNCKM 82

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|P63025|VAMP3_RAT (Vesicle-associated membrane protein 3 OS=Rattus norvegicus OX=10116 GN=Vamp3 PE=1 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 2.211e-34
Identity = 56/84 (66.67%), Postives = 68/84 (80.95%), Query Frame = 2

Query:   77 TNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + G+P     AT     N+RLQQTQ +++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:    2 STGVPSGSSAAT---GSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 82

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|P63024|VAMP3_MOUSE (Vesicle-associated membrane protein 3 OS=Mus musculus OX=10090 GN=Vamp3 PE=1 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 2.211e-34
Identity = 56/84 (66.67%), Postives = 68/84 (80.95%), Query Frame = 2

Query:   77 TNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + G+P     AT     N+RLQQTQ +++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+
Sbjct:    2 STGVPSGSSAAT---GSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 82

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|P63045|VAMP2_RAT (Vesicle-associated membrane protein 2 OS=Rattus norvegicus OX=10116 GN=Vamp2 PE=1 SV=2)

HSP 1 Score: 118.242 bits (295), Expect = 6.885e-34
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N+K+
Sbjct:   27 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 95

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A2I0LW24 (Vesicle-associated membrane protein 2 OS=Columba livia OX=8932 GN=A306_00012569 PE=4 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 3.921e-36
Identity = 62/82 (75.61%), Postives = 70/82 (85.37%), Query Frame = 2

Query:   83 GIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G  G PP  +V  S NKRLQQTQA+++EVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFE SA +LK K+WW+N K+
Sbjct:   14 GAAGPPPATSV--SSNKRLQQTQAQVDEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFETSAAKLKRKYWWKNCKM 93

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A1D5PLR5 (V-SNARE coiled-coil homology domain-containing protein OS=Gallus gallus OX=9031 GN=VAMP2 PE=4 SV=2)

HSP 1 Score: 130.183 bits (326), Expect = 5.152e-36
Identity = 62/84 (73.81%), Postives = 70/84 (83.33%), Query Frame = 2

Query:   77 TNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + G  G PP   V  S NKRLQQTQA+++EVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFE SA +LK K+WW+N K+
Sbjct:   12 STGAAGPPPATNV--SSNKRLQQTQAQVDEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFETSAAKLKRKYWWKNCKM 93

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: H0Z4K7 (V-SNARE coiled-coil homology domain-containing protein OS=Taeniopygia guttata OX=59729 PE=4 SV=1)

HSP 1 Score: 129.028 bits (323), Expect = 8.183e-36
Identity = 62/82 (75.61%), Postives = 69/82 (84.15%), Query Frame = 2

Query:   83 GIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G  G PP   V  S NKRLQQTQA+++EVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFE SA +LK K+WW+N K+
Sbjct:    2 GAAGPPPATNV--SSNKRLQQTQAQVDEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFETSAAKLKRKYWWKNCKM 81

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A226MTT1 (V-SNARE coiled-coil homology domain-containing protein OS=Callipepla squamata OX=9009 GN=ASZ78_003641 PE=4 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 1.518e-35
Identity = 62/82 (75.61%), Postives = 70/82 (85.37%), Query Frame = 2

Query:   83 GIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G  G PP  +V  S NKRLQQTQA+++EVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFE SA +LK K+WW+N K+
Sbjct:   29 GAAGPPPATSV--SSNKRLQQTQAQVDEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFETSAAKLKRKYWWKNCKM 108

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A3Q2Z5W4 (Vesicle-associated membrane protein 1 OS=Hippocampus comes OX=109280 PE=4 SV=1)

HSP 1 Score: 129.413 bits (324), Expect = 2.546e-35
Identity = 66/115 (57.39%), Postives = 84/115 (73.04%), Query Frame = 2

Query:   50 YYKFRE--TVETNGIPGSP-----PIATVPS-SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKLNSEVTPSFHISIKP 370
            Y++  E  T +  G PG+P     P A  P+ + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N K+   +  SF     P
Sbjct:   29 YHRASEMATPDAAGTPGAPDSEGGPPAAAPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKVCGIIIHSFFCFFLP 143

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Match: vamp1 (vesicle-associated membrane protein 2-like [Source:NCBI gene;Acc:103030083])

HSP 1 Score: 123.635 bits (309), Expect = 7.260e-37
Identity = 57/79 (72.15%), Postives = 69/79 (87.34%), Query Frame = 2

Query:   92 GSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G PP A    + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N K+
Sbjct:   21 GGPPGAAPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKM 99

[Close]

Query:   92 GSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G PP A    + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N K+
Sbjct:   21 GGPPGAAPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKM 99

[Close]

Query:   92 GSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G PP A    + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N K+
Sbjct:   21 GGPPGAAPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKM 99

[Close]

Query:   92 GSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G PP A    + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N K+
Sbjct:   21 GGPPGAAPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKM 99

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Match: vamp1 (vesicle-associated membrane protein 2-like [Source:NCBI gene;Acc:103030083])

HSP 1 Score: 123.25 bits (308), Expect = 7.836e-37
Identity = 58/79 (73.42%), Postives = 69/79 (87.34%), Query Frame = 2

Query:   92 GSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G PP A    + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N KL
Sbjct:   17 GGPPGAAPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKL 95

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008529.1 (pep scaffold:Pmarinus_7.0:GL484641:5659:9131:-1 gene:ENSPMAG00000007726.1 transcript:ENSPMAT00000008529.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 115.931 bits (289), Expect = 1.382e-34
Identity = 52/69 (75.36%), Postives = 63/69 (91.30%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQ GASQFE SA +LK K+WW+N K+
Sbjct:   28 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQQGASQFESSAAKLKRKYWWKNCKM 96

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Yeast
Match: SNC2 (Vesicle membrane receptor protein (v-SNARE); involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; Snc2p levels regulated by Vps45p; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins; SNC2 has a paralog, SNC1, that arose from the whole genome duplication [Source:SGD;Acc:S000005854])

HSP 1 Score: 55.4546 bits (132), Expect = 2.603e-11
Identity = 26/71 (36.62%), Postives = 47/71 (66.20%), Query Frame = 2

Query:  116 PSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            P+S NK     Q +I++ V IMR N++KV ER ++L+ ++++AD L   A  F+  A R++ + WW+++K+
Sbjct:   22 PNSQNKTAALRQ-EIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQMWWKDLKM 91

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Yeast
Match: SNC1 (Vesicle membrane receptor protein (v-SNARE); involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins; SNC1 has a paralog, SNC2, that arose from the whole genome duplication [Source:SGD;Acc:S000000028])

HSP 1 Score: 55.8398 bits (133), Expect = 2.605e-11
Identity = 23/65 (35.38%), Postives = 44/65 (67.69%), Query Frame = 2

Query:  134 RLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            R  + QA+I++ V IMR N++KV ER ++L+ ++++AD L   A  F+  A R++   W++++K+
Sbjct:   28 RTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKM 92

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Yeast
Match: NYV1 (v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane [Source:SGD;Acc:S000004083])

HSP 1 Score: 47.3654 bits (111), Expect = 1.504e-7
Identity = 21/60 (35.00%), Postives = 37/60 (61.67%), Query Frame = 2

Query:  146 TQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVK 325
            T+ +I +V+ IM  N+DK LER +++S L ++   L + +++F   A  +K   WW+ VK
Sbjct:  171 TEDQIKDVIQIMNDNIDKFLERQERVSLLVDKTSQLNSSSNKFRRKAVNIKEIMWWQKVK 230

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO42383 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1M0])

HSP 1 Score: 112.464 bits (280), Expect = 1.879e-33
Identity = 53/68 (77.94%), Postives = 61/68 (89.71%), Query Frame = 2

Query:  125 GNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
             +KRLQQTQA+++EVVDIM++NVDKVLERD KLSELDNRADALQAGASQFE SA RLK K WW+N K+
Sbjct:    2 SSKRLQQTQAQVDEVVDIMKVNVDKVLERDAKLSELDNRADALQAGASQFETSASRLKRKMWWQNCKV 69

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO43738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXX6])

HSP 1 Score: 57.3806 bits (137), Expect = 9.827e-11
Identity = 23/69 (33.33%), Postives = 44/69 (63.77%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +G   + + Q +++EV D+M  N++KVLER +++  L ++A+ L   A  F+  + RL+ K WW+N ++
Sbjct:  124 AGGDAINKVQREVDEVKDVMTKNIEKVLERGERIDILMDKAETLDNSAQTFQRHSSRLRKKMWWQNTRM 192

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO44396 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVJ7])

HSP 1 Score: 53.9138 bits (128), Expect = 5.706e-10
Identity = 26/88 (29.55%), Postives = 50/88 (56.82%), Query Frame = 2

Query:   65 ETVETNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            ++ +   I  +P  +T     +  + + + +I  VVD+M+ N+ KVL+R  KL +L ++++ L   A QF   + +L+ K WW+N +L
Sbjct:   29 DSDDGTNIFAAPAGSTNKPPSDNNISRVKNEIKGVVDVMQTNIAKVLDRGAKLDDLQDKSENLDMNAFQFRSGSRKLQRKLWWQNCRL 116

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO39013 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBE8])

HSP 1 Score: 43.8986 bits (102), Expect = 5.130e-6
Identity = 18/65 (27.69%), Postives = 39/65 (60.00%), Query Frame = 2

Query:  137 LQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKLN 331
            + + Q +++E+  IM  N+D +  R ++L  L ++A+ L + +  F++++  L    WW+NVK+ 
Sbjct:  127 IAKVQVELDEIRGIMVKNIDSIASRGERLELLIDKAEDLNSSSLTFKKTSRGLARAMWWKNVKIT 191

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: vamp3 (vesicle-associated membrane protein 3 (cellubrevin) [Source:ZFIN;Acc:ZDB-GENE-040625-45])

HSP 1 Score: 123.25 bits (308), Expect = 4.968e-37
Identity = 58/89 (65.17%), Postives = 71/89 (79.78%), Query Frame = 2

Query:  101 PIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKLNSEVTPSFHISIK 367
            P  +  +S NKRLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+     P+    I+
Sbjct:    6 PEGSGAASSNKRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKVTLSFAPNCTSQIQ 94

[Close]

Query:  101 PIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKLNSEVTPSFHISIK 367
            P  +  +S NKRLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK K+WW+N K+     P+    I+
Sbjct:    6 PEGSGAASSNKRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKVTLSFAPNCTSQIQ 94

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: vamp1 (vesicle-associated membrane protein 2-like [Source:NCBI gene;Acc:101164413])

HSP 1 Score: 121.324 bits (303), Expect = 1.561e-35
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N K+
Sbjct:   30 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKM 98

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: vamp1 (vesicle-associated membrane protein 2-like [Source:NCBI gene;Acc:101164413])

HSP 1 Score: 118.242 bits (295), Expect = 1.078e-34
Identity = 53/69 (76.81%), Postives = 65/69 (94.20%), Query Frame = 2

Query:  122 SGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            + N+RLQQTQA+++EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE SA +LK+K+WW+N K+
Sbjct:   30 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKNKYWWKNCKM 98

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: zgc:92912 (vesicle-associated membrane protein 2 [Source:NCBI gene;Acc:101173249])

HSP 1 Score: 117.472 bits (293), Expect = 2.013e-34
Identity = 53/69 (76.81%), Postives = 63/69 (91.30%), Query Frame = 2

Query:  119 SSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVK 325
            +S N+RLQQTQA++ EVVDIMR+NVDKVLERDQKLSELD+RADALQAGASQFE  A +LK+K+WW+N K
Sbjct:   31 TSSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESCAAKLKNKYWWKNCK 99

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Match: SMESG000033532.1 (SMESG000033532.1)

HSP 1 Score: 182.57 bits (462), Expect = 2.398e-60
Identity = 87/89 (97.75%), Postives = 89/89 (100.00%), Query Frame = 2

Query:   62 RETVETNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +ETVETNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVK+
Sbjct:    4 KETVETNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKM 92

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Match: SMESG000066166.1 (SMESG000066166.1)

HSP 1 Score: 129.413 bits (324), Expect = 9.543e-39
Identity = 64/83 (77.11%), Postives = 70/83 (84.34%), Query Frame = 2

Query:   83 GIPGSPPIATVPSSG-NKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            G PG PP    PS   NKRLQQTQA+++EVVDIMR+NVDKVLERD KLSELDNRADALQAGASQFE SAG+LK KFWWRN K+
Sbjct:   17 GTPGIPP----PSGPVNKRLQQTQAQVDEVVDIMRVNVDKVLERDHKLSELDNRADALQAGASQFEASAGKLKRKFWWRNCKM 95

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Match: SMESG000057424.1 (SMESG000057424.1)

HSP 1 Score: 122.865 bits (307), Expect = 9.615e-37
Identity = 60/87 (68.97%), Postives = 72/87 (82.76%), Query Frame = 2

Query:   86 IPGSPPIATV----PSS--GNKRLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            +PG PP+       PSS   NKRLQQTQA+++E+VDIM+ NVDKVLERDQKLSELDNRA+ALQAGASQFE SAG+LK KFW +N+K+
Sbjct:    8 VPGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEALQAGASQFEASAGKLKRKFWLKNLKM 94

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Match: SMESG000010550.1 (SMESG000010550.1)

HSP 1 Score: 83.5741 bits (205), Expect = 5.195e-21
Identity = 35/65 (53.85%), Postives = 51/65 (78.46%), Query Frame = 2

Query:  134 RLQQTQAKINEVVDIMRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            RLQQTQ ++++V ++MR N+ K LERD KLSE+D RA  LQ GA QF+ +A +++ KFWW+N+K+
Sbjct:   34 RLQQTQMQVDQVTNVMRENMAKALERDAKLSEMDERAAELQMGAQQFQTTAHKVQRKFWWKNIKM 98

[Close]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Match: SMESG000026855.1 (SMESG000026855.1)

HSP 1 Score: 58.151 bits (139), Expect = 6.407e-12
Identity = 24/50 (48.00%), Postives = 37/50 (74.00%), Query Frame = 2

Query:  179 MRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL 328
            MR N+DKVLERD++L +L  RA+ ++  A +F  +A R + KFWW+N+K+
Sbjct:    1 MRQNMDKVLERDKRLDDLSTRAEDMEGNAREFHANAVRARRKFWWQNIKM 50

The following BLAST results are available for this feature:

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Yeast
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VAMP2	1.434e-34	76.81	vesicle associated membrane protein 2 [Source:HGNC...	[more]
VAMP2	1.870e-34	76.81	vesicle associated membrane protein 2 [Source:HGNC...	[more]
VAMP2	2.637e-34	76.81	vesicle associated membrane protein 2 [Source:HGNC...	[more]
AC129492.3	3.300e-34	76.81	novel protein	[more]
VAMP3	3.988e-34	72.60	vesicle associated membrane protein 3 [Source:HGNC...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
snb-1	1.877e-31	70.42	Synaptobrevin-1 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]
snb-2	3.535e-24	46.51	SyNaptoBrevin related [Source:UniProtKB/TrEMBL;Ac...	[more]
snb-2	3.535e-24	46.51	SyNaptoBrevin related [Source:UniProtKB/TrEMBL;Ac...	[more]
vamp-7	9.036e-9	29.17	VAMP (Vesicle Associated Membrane Protein) homolog...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nSyb	1.320e-30	72.46	gene:FBgn0013342 transcript:FBtr0331462	[more]
nSyb	1.914e-30	72.46	gene:FBgn0013342 transcript:FBtr0306578	[more]
nSyb	1.914e-30	72.46	gene:FBgn0013342 transcript:FBtr0302310	[more]
nSyb	2.519e-30	72.46	gene:FBgn0013342 transcript:FBtr0331461	[more]
nSyb	3.251e-30	75.76	gene:FBgn0013342 transcript:FBtr0072815	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vamp3	4.548e-36	73.75	vesicle-associated membrane protein 3 (cellubrevin...	[more]
vamp3	4.548e-36	73.75	vesicle-associated membrane protein 3 (cellubrevin...	[more]
vamp1	6.320e-36	71.60	vesicle-associated membrane protein 1 [Source:ZFIN...	[more]
vamp1	6.320e-36	71.60	vesicle-associated membrane protein 1 [Source:ZFIN...	[more]
vamp3	6.559e-36	73.75	vesicle-associated membrane protein 3 (cellubrevin...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vamp3	1.508e-35	71.79	vesicle associated membrane protein 3 [Source:NCBI...	[more]
vamp3	1.556e-35	71.79	vesicle associated membrane protein 3 [Source:NCBI...	[more]
idh1	4.263e-35	76.06	isocitrate dehydrogenase 1 (NADP+) [Source:Xenbase...	[more]
vamp4	1.894e-11	29.87	vesicle associated membrane protein 4 [Source:NCBI...	[more]
vamp4	6.599e-11	30.43	vesicle associated membrane protein 4 [Source:NCBI...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Vamp3	3.161e-35	66.67	vesicle-associated membrane protein 3 [Source:MGI ...	[more]
Vamp2	9.842e-35	76.81	vesicle-associated membrane protein 2 [Source:MGI ...	[more]
Vamp1	2.524e-34	76.81	vesicle-associated membrane protein 1 [Source:MGI ...	[more]
Vamp1	3.668e-34	76.81	vesicle-associated membrane protein 1 [Source:MGI ...	[more]
Vamp1	6.075e-34	76.81	vesicle-associated membrane protein 1 [Source:MGI ...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P13701\|SYB_TETCF	3.042e-35	69.51	Synaptobrevin OS=Tetronarce californica OX=7787 PE...	[more]
sp\|Q27236\|SYBL_SCHMA	9.430e-35	78.87	Synaptobrevin-like protein OS=Schistosoma mansoni ...	[more]
sp\|P63025\|VAMP3_RAT	2.211e-34	66.67	Vesicle-associated membrane protein 3 OS=Rattus no...	[more]
sp\|P63024\|VAMP3_MOUSE	2.211e-34	66.67	Vesicle-associated membrane protein 3 OS=Mus muscu...	[more]
sp\|P63045\|VAMP2_RAT	6.885e-34	76.81	Vesicle-associated membrane protein 2 OS=Rattus no...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2I0LW24	3.921e-36	75.61	Vesicle-associated membrane protein 2 OS=Columba l...	[more]
A0A1D5PLR5	5.152e-36	73.81	V-SNARE coiled-coil homology domain-containing pro...	[more]
H0Z4K7	8.183e-36	75.61	V-SNARE coiled-coil homology domain-containing pro...	[more]
A0A226MTT1	1.518e-35	75.61	V-SNARE coiled-coil homology domain-containing pro...	[more]
A0A3Q2Z5W4	2.546e-35	57.39	Vesicle-associated membrane protein 1 OS=Hippocamp...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vamp1	7.260e-37	72.15	vesicle-associated membrane protein 2-like [Source...	[more]
vamp1	7.260e-37	72.15	vesicle-associated membrane protein 2-like [Source...	[more]
vamp1	7.260e-37	72.15	vesicle-associated membrane protein 2-like [Source...	[more]
vamp1	7.260e-37	72.15	vesicle-associated membrane protein 2-like [Source...	[more]
vamp1	7.836e-37	73.42	vesicle-associated membrane protein 2-like [Source...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000008529.1	1.382e-34	75.36	pep scaffold:Pmarinus_7.0:GL484641:5659:9131:-1 ge...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
SNC2	2.603e-11	36.62	Vesicle membrane receptor protein (v-SNARE); invol...	[more]
SNC1	2.605e-11	35.38	Vesicle membrane receptor protein (v-SNARE); invol...	[more]
NYV1	1.504e-7	35.00	v-SNARE component of the vacuolar SNARE complex; i...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO42383	1.879e-33	77.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43738	9.827e-11	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44396	5.706e-10	29.55	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39013	5.130e-6	27.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vamp3	4.968e-37	65.17	vesicle-associated membrane protein 3 (cellubrevin...	[more]
vamp3	4.968e-37	65.17	vesicle-associated membrane protein 3 (cellubrevin...	[more]
vamp1	1.561e-35	76.81	vesicle-associated membrane protein 2-like [Source...	[more]
vamp1	1.078e-34	76.81	vesicle-associated membrane protein 2-like [Source...	[more]
zgc:92912	2.013e-34	76.81	vesicle-associated membrane protein 2 [Source:NCBI...	[more]

BLAST of V-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000033532.1	2.398e-60	97.75	SMESG000033532.1	[more]
SMESG000066166.1	9.543e-39	77.11	SMESG000066166.1	[more]
SMESG000057424.1	9.615e-37	68.97	SMESG000057424.1	[more]
SMESG000010550.1	5.195e-21	53.85	SMESG000010550.1	[more]
SMESG000026855.1	6.407e-12	48.00	SMESG000026855.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030734 ID=SMED30030734|Name=V-SNARE coiled-coil homology domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=469bp
AATTGAAAACATATTAACTTAATTTACAATGACTTTTGATAATGATTTTT
ATTATAAATTTAGAGAAACTGTTGAAACTAATGGTATTCCTGGTTCACCA
CCAATAGCAACTGTCCCATCAAGTGGTAACAAGAGACTTCAACAAACACA
AGCTAAGATAAATGAAGTAGTTGATATTATGAGAATGAATGTTGATAAAG
TGTTAGAAAGAGATCAAAAATTATCAGAACTTGATAATAGAGCTGATGCT
TTGCAAGCAGGAGCGTCACAATTTGAAGAAAGTGCGGGTAGATTAAAAAG
CAAATTTTGGTGGCGTAATGTTAAATTAAATTCCGAGGTCACGCCATCCT
TTCATATTTCTATAAAACCCATCAGAGCTTTCATCTGGAGTTTTCGGTTT
TTATCAGTCCATTCAGCACACGTCAATACTGTCTTTGACCTCATCACAAG
ATGCTTATCATAATTGGAG

protein sequence of SMED30030734-orf-1

>SMED30030734-orf-1 ID=SMED30030734-orf-1|Name=SMED30030734-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=145bp
MTFDNDFYYKFRETVETNGIPGSPPIATVPSSGNKRLQQTQAKINEVVDI
MRMNVDKVLERDQKLSELDNRADALQAGASQFEESAGRLKSKFWWRNVKL
NSEVTPSFHISIKPIRAFIWSFRFLSVHSAHVNTVFDLITRCLS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR016444	Synaptobrevin/VAMP
IPR042855	V_SNARE_CC
IPR001388	Synaptobrevin

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005739	mitochondrion
GO:0009986	cell surface
GO:0016020	membrane
GO:0030054	cell junction
GO:0030659	cytoplasmic vesicle membrane
GO:0030672	synaptic vesicle membrane
GO:0031201	SNARE complex
GO:0031410	cytoplasmic vesicle
GO:0035579	specific granule membrane
GO:0043005	neuron projection
GO:0043195	terminal bouton
GO:0045202	synapse
GO:0070821	tertiary granule membrane

Vocabulary: **biological process**
Term	Definition
GO:0016192	vesicle-mediated transport
GO:0006887	exocytosis
GO:0035493	SNARE complex assembly

Vocabulary: **molecular function**
Term	Definition
GO:0005484	SNAP receptor activity
GO:0019905	syntaxin binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 65..85
None	No IPR available	GENE3D	G3DSA:1.20.5.110		coord: 11..107 e-value: 1.7E-34 score: 120.1
None	No IPR available	PANTHER	PTHR45701:SF5	VESICLE-ASSOCIATED MEMBRANE PROTEIN 2	coord: 22..101
None	No IPR available	CDD	cd15870	R-SNARE_VAMP2	coord: 35..97 e-value: 8.62423E-41 score: 128.657
None	No IPR available	SUPERFAMILY	SSF58038	SNARE fusion complex	coord: 32..97
IPR001388	Synaptobrevin	PRINTS	PR00219	SYNAPTOBREVN	coord: 61..80 score: 62.97 coord: 41..60 score: 61.76
IPR001388	Synaptobrevin	PFAM	PF00957	Synaptobrevin	coord: 34..101 e-value: 3.7E-25 score: 87.5
IPR001388	Synaptobrevin	PROSITE	PS00417	SYNAPTOBREVIN	coord: 54..73
IPR016444	Synaptobrevin/Vesicle-associated membrane protein	PANTHER	PTHR45701	FAMILY NOT NAMED	coord: 22..101
IPR042855	v-SNARE, coiled-coil homology domain	PROSITE	PS50892	V_SNARE	coord: 36..96 score: 17.622