G/T mismatch-specific thymine DNA glycosylase

Overview
NameG/T mismatch-specific thymine DNA glycosylase
Smed IDSMED30030696
Length (bp)703
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G/T mismatch-specific thymine DNA glycosylase (SMED30030696) t-SNE clustered cells

Violin plots show distribution of expression levels for G/T mismatch-specific thymine DNA glycosylase (SMED30030696) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G/T mismatch-specific thymine DNA glycosylase (SMED30030696) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G/T mismatch-specific thymine DNA glycosylase (SMED30030696) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030696

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 21

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig731newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig731uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig5365newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig5365uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig730newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig730uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig5029newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000043196.1 Contig5029uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000004734.1 Contig730newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000004734.1 Contig730uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000056926.1 Contig731newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000056926.1 Contig731uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000049264.1 SMESG000009696.1 SMESG000009679.1 SMESG000009674.1 Contig5365newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000049264.1 SMESG000009696.1 SMESG000009679.1 SMESG000009674.1 Contig5365uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000016436.1 Contig5029newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030696SMESG000016436.1 Contig5029uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
X1 cellSMED30030696SMESG000043196.1 SmedASXL_011853SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
reproductive organSMED30030696SMESG000043196.1 Contig5365newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30030696SMESG000043196.1 Contig5365uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30030696SMESG000049264.1 SMESG000009696.1 SMESG000009679.1 SMESG000009674.1 Contig5365newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30030696SMESG000049264.1 SMESG000009696.1 SMESG000009679.1 SMESG000009674.1 Contig5365uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Human
Match: TDG (thymine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:11700])

HSP 1 Score: 147.132 bits (370), Expect = 2.083e-41
Identity = 81/186 (43.55%), Postives = 112/186 (60.22%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT ++ +VMPS+S + A+FP+  DK+ +++KLK++RD L
Sbjct:  116 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL 299
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Human
Match: TDG (thymine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:11700])

HSP 1 Score: 146.747 bits (369), Expect = 2.147e-41
Identity = 81/186 (43.55%), Postives = 112/186 (60.22%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT ++ +VMPS+S + A+FP+  DK+ +++KLK++RD L
Sbjct:  112 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL 295
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Human
Match: TDG (thymine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:11700])

HSP 1 Score: 119.398 bits (298), Expect = 4.348e-32
Identity = 66/153 (43.14%), Postives = 90/153 (58.82%), Query Frame = 3 
Query:  237 SHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
             HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT ++ +VMPS+S + A+FP+  DK+ +++KLK++RD L
Sbjct:    6 GHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL 156
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Human
Match: TDG (thymine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:11700])

HSP 1 Score: 98.5969 bits (244), Expect = 2.153e-24
Identity = 62/151 (41.06%), Postives = 80/151 (52.98%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNS 569
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FW           E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT +
Sbjct:  116 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWLS---------EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTET 257
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Human
Match: TDG (thymine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:11700])

HSP 1 Score: 80.8777 bits (198), Expect = 4.405e-19
Identity = 43/92 (46.74%), Postives = 55/92 (59.78%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSK 410
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS+
Sbjct:   20 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSR 109
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Fly
Match: Thd1 (gene:FBgn0026869 transcript:FBtr0333706)

HSP 1 Score: 137.117 bits (344), Expect = 1.474e-36
Identity = 67/173 (38.73%), Postives = 108/173 (62.43%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            + +PD + +NLDI+ VGINP + +    HHYAG  N FWKC   + +   +  +   +D++L+K GIGFTN+ +RAT  + DL+++E++     L EK+ ++RPK+ VFNG LI++    +K    G Q      T++ ++VMPS+S + A+ P+  DK+ F+  LK+ RD L
Sbjct:  777 RTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLT--QEQMSADEDHKLIKQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVFNGKLIFEVFSGKKEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAADKVPFYAALKKFRDFL 947
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Fly
Match: Thd1 (gene:FBgn0026869 transcript:FBtr0345197)

HSP 1 Score: 137.117 bits (344), Expect = 1.474e-36
Identity = 67/173 (38.73%), Postives = 108/173 (62.43%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            + +PD + +NLDI+ VGINP + +    HHYAG  N FWKC   + +   +  +   +D++L+K GIGFTN+ +RAT  + DL+++E++     L EK+ ++RPK+ VFNG LI++    +K    G Q      T++ ++VMPS+S + A+ P+  DK+ F+  LK+ RD L
Sbjct:  777 RTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLT--QEQMSADEDHKLIKQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVFNGKLIFEVFSGKKEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAADKVPFYAALKKFRDFL 947
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Fly
Match: Thd1 (gene:FBgn0026869 transcript:FBtr0089106)

HSP 1 Score: 137.117 bits (344), Expect = 1.474e-36
Identity = 67/173 (38.73%), Postives = 108/173 (62.43%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            + +PD + +NLDI+ VGINP + +    HHYAG  N FWKC   + +   +  +   +D++L+K GIGFTN+ +RAT  + DL+++E++     L EK+ ++RPK+ VFNG LI++    +K    G Q      T++ ++VMPS+S + A+ P+  DK+ F+  LK+ RD L
Sbjct:  777 RTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLT--QEQMSADEDHKLIKQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVFNGKLIFEVFSGKKEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAADKVPFYAALKKFRDFL 947
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Zebrafish
Match: tdg.2 (thymine DNA glycosylase, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-131121-30])

HSP 1 Score: 137.502 bits (345), Expect = 5.146e-38
Identity = 76/178 (42.70%), Postives = 101/178 (56.74%), Query Frame = 3 
Query:  162 LPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLK-YGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            LPD+I  NLD+L +GINP + S     HY    N FWKC   S +      L    D  L + YGIGFTN+  R T  + DLS +E+      L EK+  YRP I VFNG  IY    K IF  K K    GLQ +   +T ++ ++MPS+S + A+FP+  DK+ F++KLKE+RD L
Sbjct:  133 LPDVITHNLDMLIIGINPGLLSAYKGRHYPNPGNHFWKCLFLSGLT--NEQLNHMHDQTLPEHYGIGFTNMVERTTPGSKDLSNKEIREGGHQLLEKLQTYRPLIAVFNGKCIYEIFCKEIFGVKAKNLEFGLQPYKVPETETVCYLMPSSSPRCAQFPRAQDKVHFYIKLKELRDQL 308
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Zebrafish
Match: tdg.2 (thymine DNA glycosylase, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-131121-30])

HSP 1 Score: 137.117 bits (344), Expect = 5.794e-38
Identity = 76/178 (42.70%), Postives = 101/178 (56.74%), Query Frame = 3 
Query:  162 LPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLK-YGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            LPD+I  NLD+L +GINP + S     HY    N FWKC   S +      L    D  L + YGIGFTN+  R T  + DLS +E+      L EK+  YRP I VFNG  IY    K IF  K K    GLQ +   +T ++ ++MPS+S + A+FP+  DK+ F++KLKE+RD L
Sbjct:  132 LPDVITHNLDMLIIGINPGLLSAYKGRHYPNPGNHFWKCLFLSGLT--NEQLNHMHDQTLPEHYGIGFTNMVERTTPGSKDLSNKEIREGGHQLLEKLQTYRPLIAVFNGKCIYEIFCKEIFGVKAKNLEFGLQPYKVPETETVCYLMPSSSPRCAQFPRAQDKVHFYIKLKELRDQL 307
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Zebrafish
Match: tdg.1 (thymine DNA glycosylase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-050522-44])

HSP 1 Score: 134.42 bits (337), Expect = 1.093e-36
Identity = 75/180 (41.67%), Postives = 106/180 (58.89%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            + LPDI+  NLD + +GINP + +      + G  N FWKC   S     E  L   DD  L  KYGIGFTN+ +RAT  + DLS +EL      L EKI +++P I VFNG  IY    + +F +K K    GLQ     D+++ L++MPS+S + A+FP+  DK+ F++KL+E+RD L
Sbjct:  150 RTLPDILIPNLDYVIIGINPGLMAAYIGRWFPGPGNHFWKCLFLSGFT--EKLLNHMDDQSLPEKYGIGFTNMVARATPGSKDLSSKELREGGKILVEKIKQFKPLIAVFNGKCIYEMFCRELFGKKPKTLEFGLQPHKIPDSDTALYLMPSSSARCAQFPRAQDKVHFYIKLRELRDQL 327
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Zebrafish
Match: tdg.1 (thymine DNA glycosylase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-050522-44])

HSP 1 Score: 134.42 bits (337), Expect = 1.093e-36
Identity = 75/180 (41.67%), Postives = 106/180 (58.89%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            + LPDI+  NLD + +GINP + +      + G  N FWKC   S     E  L   DD  L  KYGIGFTN+ +RAT  + DLS +EL      L EKI +++P I VFNG  IY    + +F +K K    GLQ     D+++ L++MPS+S + A+FP+  DK+ F++KL+E+RD L
Sbjct:  150 RTLPDILIPNLDYVIIGINPGLMAAYIGRWFPGPGNHFWKCLFLSGFT--EKLLNHMDDQSLPEKYGIGFTNMVARATPGSKDLSSKELREGGKILVEKIKQFKPLIAVFNGKCIYEMFCRELFGKKPKTLEFGLQPHKIPDSDTALYLMPSSSARCAQFPRAQDKVHFYIKLRELRDQL 327
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Zebrafish
Match: tdg.2 (thymine DNA glycosylase, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-131121-30])

HSP 1 Score: 70.8626 bits (172), Expect = 1.743e-14
Identity = 36/83 (43.37%), Postives = 44/83 (53.01%), Query Frame = 3 
Query:  162 LPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLK-YGIGFTNICSRATVTANDLS 407
            LPD+I  NLD+L +GINP + S     HY    N FWKC   S +      L    D  L + YGIGFTN+  R T  + DLS
Sbjct:  132 LPDVITHNLDMLIIGINPGLLSAYKGRHYPNPGNHFWKCLFLSGLT--NEQLNHMHDQTLPEHYGIGFTNMVERTTPGSKDLS 212
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Xenopus
Match: tdg (thymine DNA glycosylase [Source:NCBI gene;Acc:448432])

HSP 1 Score: 142.51 bits (358), Expect = 2.186e-39
Identity = 76/180 (42.22%), Postives = 108/180 (60.00%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLK--ITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +  ++  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L EK+ KY+P++  FNG  IY    K IF  K+K    G+Q     +T+++ +VMPS+S + A+FP+  DK+  ++KLKE+R+ L
Sbjct:  170 KTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFLSGLSDMQ--LNHLDDHSLPEKYGIGFTNMVERTTPGSKDLSSKEFREGGRILLEKLQKYKPRVAAFNGKCIYEIFSKEIFGVKIKKFEFGIQPHRVPETDTVCYVMPSSSARCAQFPRAQDKVHHYIKLKELRNQL 347
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Xenopus
Match: tdg (thymine DNA glycosylase [Source:NCBI gene;Acc:448432])

HSP 1 Score: 142.124 bits (357), Expect = 2.287e-39
Identity = 76/180 (42.22%), Postives = 108/180 (60.00%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLK--ITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +  ++  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L EK+ KY+P++  FNG  IY    K IF  K+K    G+Q     +T+++ +VMPS+S + A+FP+  DK+  ++KLKE+R+ L
Sbjct:  157 KTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFLSGLSDMQ--LNHLDDHSLPEKYGIGFTNMVERTTPGSKDLSSKEFREGGRILLEKLQKYKPRVAAFNGKCIYEIFSKEIFGVKIKKFEFGIQPHRVPETDTVCYVMPSSSARCAQFPRAQDKVHHYIKLKELRNQL 334
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Xenopus
Match: tdg (thymine DNA glycosylase [Source:NCBI gene;Acc:448432])

HSP 1 Score: 142.124 bits (357), Expect = 2.935e-39
Identity = 76/180 (42.22%), Postives = 108/180 (60.00%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLK--ITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +  ++  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L EK+ KY+P++  FNG  IY    K IF  K+K    G+Q     +T+++ +VMPS+S + A+FP+  DK+  ++KLKE+R+ L
Sbjct:  157 KTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFLSGLSDMQ--LNHLDDHSLPEKYGIGFTNMVERTTPGSKDLSSKEFREGGRILLEKLQKYKPRVAAFNGKCIYEIFSKEIFGVKIKKFEFGIQPHRVPETDTVCYVMPSSSARCAQFPRAQDKVHHYIKLKELRNQL 334
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Mouse
Match: Tdg (thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI:108247])

HSP 1 Score: 147.132 bits (370), Expect = 1.028e-41
Identity = 81/186 (43.55%), Postives = 112/186 (60.22%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT ++ +VMPS+S + A+FP+  DK+ +++KLK++RD L
Sbjct:  103 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL 286
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Mouse
Match: Tdg (thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI:108247])

HSP 1 Score: 147.517 bits (371), Expect = 1.236e-41
Identity = 81/186 (43.55%), Postives = 112/186 (60.22%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT ++ +VMPS+S + A+FP+  DK+ +++KLK++RD L
Sbjct:  127 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL 310
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Mouse
Match: Tdg (thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI:108247])

HSP 1 Score: 106.301 bits (264), Expect = 5.836e-28
Identity = 65/151 (43.05%), Postives = 84/151 (55.63%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNS 569
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT +
Sbjct:   19 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTET 167
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Mouse
Match: Tdg (thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI:108247])

HSP 1 Score: 80.8777 bits (198), Expect = 3.121e-19
Identity = 43/92 (46.74%), Postives = 55/92 (59.78%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSK 410
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS+
Sbjct:   20 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSR 109
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Mouse
Match: Tdg (thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI:108247])

HSP 1 Score: 78.5666 bits (192), Expect = 1.455e-17
Identity = 40/84 (47.62%), Postives = 50/84 (59.52%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRAT 386
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T
Sbjct:  103 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTT 184
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. UniProt/SwissProt
Match: sp|P56581|TDG_MOUSE (G/T mismatch-specific thymine DNA glycosylase OS=Mus musculus OX=10090 GN=Tdg PE=1 SV=2)

HSP 1 Score: 147.517 bits (371), Expect = 8.648e-41
Identity = 81/186 (43.55%), Postives = 112/186 (60.22%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT ++ +VMPS+S + A+FP+  DK+ +++KLK++RD L
Sbjct:  127 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL 310
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. UniProt/SwissProt
Match: sp|Q13569|TDG_HUMAN (G/T mismatch-specific thymine DNA glycosylase OS=Homo sapiens OX=9606 GN=TDG PE=1 SV=2)

HSP 1 Score: 147.132 bits (370), Expect = 1.000e-40
Identity = 81/186 (43.55%), Postives = 112/186 (60.22%), Query Frame = 3 
Query:  141 DSEFL-KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            ++E L K LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   E  L   DD+ L  KYGIGFTN+  R T  + DLS +E       L +K+ KY+P+I VFNG  IY    K +F  K+K    GLQ     DT ++ +VMPS+S + A+FP+  DK+ +++KLK++RD L
Sbjct:  116 EAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLS--EVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL 299
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. UniProt/SwissProt
Match: sp|O59825|TDG_SCHPO (G/U mismatch-specific uracil DNA glycosylase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=thp1 PE=3 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 3.378e-24
Identity = 66/215 (30.70%), Postives = 110/215 (51.16%), Query Frame = 3 
Query:   42 VDNFTQSRKVSV*SXXXXXXXXXXXXXXXXXXMDSEFLKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVF---NGIL--IYKTIFKRKLKIT---GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEI 662
            ++N  ++R+V+V           +      + +D   L+ +PD I EN   + VG+NP I S    H +A  SN FWK  N SK++       + +D  L  +G+G TN+C+R + +  DL KEE++     L EK+ +YRP++ +F    GI   +YK +  +KL  T   G Q   + D N  +FV  S+SG+ A +     + ++ L  +E+
Sbjct:  102 LENGLRNRRVNVTKKSTLKASVKKSTLKKKNEVDPALLQGVPDYICENPYAIIVGLNPGITSSLKGHAFASPSNRFWKMLNKSKLLEGNAEFTYLNDKDLPAHGLGITNLCARPSSSGADLRKEEMQDGARILYEKVKRYRPQVGLFISGKGIWEEMYKMLTGKKLPKTFVFGWQPEKFGDAN--VFVGISSSGRAAGYSDEKKQNLWNLFAEEV 314
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. UniProt/SwissProt
Match: sp|P43343|MUG_SERMA (G/U mismatch-specific DNA glycosylase OS=Serratia marcescens OX=615 GN=mug PE=3 SV=1)

HSP 1 Score: 82.4185 bits (202), Expect = 1.749e-18
Identity = 46/146 (31.51%), Postives = 77/146 (52.74%), Query Frame = 3 
Query:  168 DIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKN 605
            +++  NL ++F GINP ++S    + +A  SN FWK  + +     E+ L      +L   G G T + +R TV A++LS++EL      L+EKI++Y+P+ +   G   + T F  K    G Q     +T   ++V+P+ SG N
Sbjct:    2 ELLAPNLRVVFCGINPGLSSAHQGYPFANGSNRFWKVIHQAGFT--ESQLAPEQWQQLKDNGCGITALVARPTVAASELSRDELRSGGEALQEKILRYQPRALAILGKQAFTTAFGVKNAPWGKQTLTLGETE--VWVLPNPSGLN 143
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. UniProt/SwissProt
Match: sp|Q6D9D7|MUG_PECAS (G/U mismatch-specific DNA glycosylase OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) OX=218491 GN=mug PE=3 SV=1)

HSP 1 Score: 80.4925 bits (197), Expect = 1.351e-17
Identity = 45/149 (30.20%), Postives = 76/149 (51.01%), Query Frame = 3 
Query:  159 ILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKN 605
            ++ DI+  NL ++F GINP +++    +H+A  +N FWK  + +     E  L   ++  LL  G G T +  R TV A +L ++EL      + EK+ +Y+P+ +   G   +   F  K    G QE    +T   ++V+P+ SG N
Sbjct:    1 MITDILAMNLQVVFCGINPGLSTAHHGYHFANPNNRFWKVIHQAGFT--ERLLTPAEEQHLLDTGCGITMLVERPTVEATELGRDELLQGGNAIVEKMTRYQPRALAVLGKQAFSQAFGIKKVSWGRQERRIGETQ--VWVLPNPSGLN 145
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. TrEMBL
Match: A0A3P6NTE1 (UDG domain-containing protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS94 PE=4 SV=1)

HSP 1 Score: 171.014 bits (432), Expect = 1.970e-48
Identity = 81/171 (47.37%), Postives = 112/171 (65.50%), Query Frame = 3 
Query:  162 LPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            LPD +KE LDI+ VGINPSIAS    HHYAG  N FW C   + +VP E  +   DD  +L YGIGFTN+C+RAT  A +L+++E++     + +KI KY+PKI VFNG  IY+     K    G Q  P A T++++FVMPS+S + A+ P+  DKL FF+ L+++R+ L
Sbjct:   51 LPDHLKEGLDIVIVGINPSIASAHLGHHYAGPGNHFWTCLTEAGLVPTE--VTCYDDMNMLDYGIGFTNVCTRATKGAAELTRKEMKAGSAVMLDKIRKYKPKIAVFNGKGIYEAFIGHKNFSMGKQPQPLAGTDTVVFVMPSSSARCAQLPRAEDKLPFFIALRKLREYL 219
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. TrEMBL
Match: A0A183PSR6 (UDG domain-containing protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS17402 PE=4 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 6.427e-47
Identity = 78/171 (45.61%), Postives = 111/171 (64.91%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRD 668
            K LPD +KE LDI+ VGINPS+AS    HHYAG  N FW C + + +VP+  ++   DD ++L YGIGFTN+C+R T  A +L+++E++     + EK+ KY+PKI VFNG  IY+     K    G Q      T+ ++FVMPS+S + A+ P+  DKL FFL L+++RD
Sbjct:   23 KSLPDHLKEGLDIVIVGINPSLASAHVGHHYAGPGNHFWTCLSQAGLVPM--AVSCYDDSKMLDYGIGFTNVCTRPTKGAAELTRKEMKAGAAIMLEKMRKYKPKIAVFNGKGIYEAYVGHKNFCMGRQPTTLDGTDIVIFVMPSSSARCAQLPRAEDKLPFFLALRKLRD 191
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. TrEMBL
Match: A0A3R7CLJ3 (G/T mismatch-specific thymine DNA glycosylase (Fragment) OS=Clonorchis sinensis OX=79923 GN=TDG PE=4 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 1.058e-46
Identity = 79/171 (46.20%), Postives = 110/171 (64.33%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRD 668
            K+LPD +KE LDI+ VGINPS+AS    HHYAG  N FW C + + +VP    +   DD R+L YGIGFTN+C+R T  A +L+++E++     + EK+ KYRPKI VFNG  IY+     K    G Q      T++ +FVMPS+S + A+ P+  DKL FF+ L+++RD
Sbjct:   52 KVLPDHLKEGLDIVIVGINPSLASASVGHHYAGPGNHFWTCISQAGLVP--EMVTCYDDERMLDYGIGFTNVCTRPTKGAAELTRKEMKAGAAIMLEKMRKYRPKIAVFNGKGIYEAYVGHKNFSMGRQPTTLDGTDTTIFVMPSSSARCAQLPRAEDKLPFFVALRKLRD 220
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. TrEMBL
Match: V4B756 (UDG domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_132396 PE=4 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 1.108e-46
Identity = 78/174 (44.83%), Postives = 112/174 (64.37%), Query Frame = 3 
Query:  153 LKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            L++LPD + ENLDIL VGINP + +    HHYAG  N FWKC   S ++P    +   DD++L+++GIGFTNIC+R T  + DL K E++     LKEK+ KYRPKI  FNG  IY+     K    G Q  P   T+++++VMPS+S + A+ P+  DK+ F+  LK++RD++
Sbjct:   19 LRLLPDHLAENLDILIVGINPGLFAAYVGHHYAGPGNHFWKCLYLSGLIP--EPMNAYDDFKLIEHGIGFTNICARTTRGSADLKKPEIQEGGRILKEKLQKYRPKIAAFNGKGIYEIFVGHKKFSIGKQPEPLEGTDTVVYVMPSSSARCAQLPRAVDKVPFYEALKKLRDHI 190
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. TrEMBL
Match: A0A4E0RP31 (G/T mismatch-specific thymine DNA glycosylase OS=Fasciola hepatica OX=6192 GN=D915_000397 PE=4 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 1.175e-46
Identity = 84/171 (49.12%), Postives = 114/171 (66.67%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRD 668
            K LPD +KENLDI+ VGINPS+AS    HHYAG+ N FW C   S +VP+  S+   DD ++L YGIGFTN+C+R T  A +L+++E++     + EK+ KYRPKI VFNG  IY+     K    G Q  P   TN+I+FVMPS+S + A+ P+  DKL FF+ L+++RD
Sbjct:   94 KTLPDHLKENLDIVIVGINPSLASAHIGHHYAGQGNHFWTCLFQSGLVPM--SVNCYDDMKMLDYGIGFTNVCTRPTKGAAELTRKEMKAGAAIMLEKMRKYRPKIAVFNGKGIYEAYVGHKNFSMGRQPAPLDGTNTIVFVMPSSSARCAQLPRAEDKLPFFVALRKLRD 262
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Cavefish
Match: tdg.2 (G/T mismatch-specific thymine DNA glycosylase-like [Source:NCBI gene;Acc:103045467])

HSP 1 Score: 135.191 bits (339), Expect = 2.883e-37
Identity = 74/178 (41.57%), Postives = 102/178 (57.30%), Query Frame = 3 
Query:  162 LPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            LPDII  +LDIL +GINP + S     HY    N FWKC   S +   E  L +  D  L  ++GIGFTN+  R T  + DLS +E+      L EK+  YRP+I  FNG  IY    K IF  K K    GLQ +    T ++ ++MPS+S + A+FP+  DK+ F+++LKE+RD +
Sbjct:  135 LPDIITYDLDILIIGINPGLLSAYKGRHYPNPGNHFWKCLFLSGLT--EEQLNYMHDQTLPDRHGIGFTNMVERTTPGSKDLSNKEIREGGKQLLEKLQMYRPRIAAFNGKGIYEIFCKEIFGVKAKNLEFGLQPYKVPGTETVCYLMPSSSPRCAQFPRAQDKVHFYIRLKELRDQM 310
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Cavefish
Match: tdg.1 (G/T mismatch-specific thymine DNA glycosylase [Source:NCBI gene;Acc:103043944])

HSP 1 Score: 133.65 bits (335), Expect = 2.204e-36
Identity = 78/187 (41.71%), Postives = 106/187 (56.68%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTD-------DYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            K LPDI+  NLD + +GINP + +      + G  N FWKC   S         GFTD       D  L  KYGIGFTN+ +RAT  + DLS +EL      L EKI +++P I VFNG  IY    + IF +K K    GLQ     D+ + L++MPS+S + A+FP+  DK+ F++KL+E+RD L
Sbjct:  154 KTLPDILTPNLDYVIIGINPGLMAAYIGRWFPGPGNHFWKCLFLS---------GFTDQLLNHMHDQTLPEKYGIGFTNMVARATPGSKDLSSKELREGGKILVEKIKQFKPLIAVFNGKCIYEMFCREIFGKKPKTLEFGLQPHKIPDSETALYLMPSSSARCAQFPRAQDKVHFYIKLRELRDQL 331
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Sea Lamprey
Match: tdg.2 (thymine DNA glycosylase, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-131121-30])

HSP 1 Score: 134.035 bits (336), Expect = 2.176e-37
Identity = 74/181 (40.88%), Postives = 107/181 (59.12%), Query Frame = 3 
Query:  150 FLKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILI----YKTIFKRKLKITGLQEFP--YADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDN 671
             LK LPDI+  NLDI+ +GINP + +    HHY G  N FWKC   S +   +  L   DD  L  KYGIGFTN+  R T  + DL  +E+      L +K+ K++P I VFNG  I    +K +F  K+K     E P    +T+ I++VMPS+S + A+FP+  DK+ F++K+KE+R++
Sbjct:  169 LLKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFLSGLT--DQLLNHLDDKSLPEKYGIGFTNMVERTTPGSKDLKSKEIREGGKILLQKLQKFKPTIAVFNGKCIFEIFFKEVFGEKIKNFQFGEQPNKIPETDIIVYVMPSSSARCAQFPRAQDKVHFYIKMKELRNS 347
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Nematostella
Match: EDO42559 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S194])

HSP 1 Score: 149.058 bits (375), Expect = 1.699e-44
Identity = 76/170 (44.71%), Postives = 105/170 (61.76%), Query Frame = 3 
Query:  159 ILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRD 668
            +LPD + ENLDILF+GINP + S    HHYAG +N FW C   S +VP    L F DD +   YGIG TNI  R T  ++DLS++E++  V  L  K+ + +P +  FNG  IY+   K K +I G Q      TN +++VMPS+SG+   +P+ +DKL FF +LK +RD
Sbjct:   55 LLPDRVAENLDILFIGINPGLTSAYKGHHYAGPNNHFWPCLYDSGLVP--EKLTFRDDEKCPAYGIGLTNIVERTTRGSSDLSRKEIKDGVDALIVKVKRLKPLVACFNGKGIYEIFSKSKCEI-GRQTKCIPGTNVVVYVMPSSSGRTMTYPRASDKLKFFTELKSLRD 221
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Medaka
Match: tdg.2 (G/T mismatch-specific thymine DNA glycosylase [Source:NCBI gene;Acc:101162834])

HSP 1 Score: 142.124 bits (357), Expect = 3.666e-39
Identity = 78/180 (43.33%), Postives = 104/180 (57.78%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLL-KYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            K LPD+I  NLDIL +GINP + S    HHY    N FWKC   S +   E  L +  D  L  KY IGFTN+  R T  + DLS +E+      L EK+ KY+P I  FNG  IY    K IF  K K    GLQ +   +T ++ ++MPS+S + A+FP+  DK+ F++KLKE+RD +
Sbjct:  274 KTLPDVITYNLDILIIGINPGLLSAFKGHHYPNPGNHFWKCLFLSGLT--EEQLNYMHDQNLPEKYSIGFTNMVERTTPGSKDLSSKEIREGGRQLLEKLQKYKPLIAAFNGKGIYEIFCKEIFGVKAKNLEFGLQPYKIPETETVCYLMPSSSPRCAQFPRAQDKVHFYIKLKELRDQM 451
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Medaka
Match: tdg.1 (thymine DNA glycosylase [Source:NCBI gene;Acc:101155844])

HSP 1 Score: 130.568 bits (327), Expect = 4.119e-35
Identity = 73/180 (40.56%), Postives = 104/180 (57.78%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRL-LKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIY----KTIFKRKLKIT--GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            K LPD++  NLD + +GINP + +      + G  N FWKC   S     E+ L    D  L +KY +GFTN+ +RAT  + DLS +EL      L EK+ KY+P I VFNG  IY    + +F +K +    GLQ     D +  LF+MPS+S + A+FP+  DK+ F++KL+E+RD L
Sbjct:  165 KTLPDLLDHNLDYVIIGINPGLMAAYIGRWFPGPGNHFWKCLFLSGFT--EDQLNHMHDTTLPVKYKMGFTNMVARATPGSKDLSSKELREGGKILVEKLKKYKPLIAVFNGKCIYEMFCRELFGKKPQKLEFGLQPHKIPDCDVALFLMPSSSARCAQFPRAQDKVHFYIKLRELRDQL 342
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Medaka
Match: tdg.1 (thymine DNA glycosylase [Source:NCBI gene;Acc:101155844])

HSP 1 Score: 130.954 bits (328), Expect = 9.604e-35
Identity = 75/181 (41.44%), Postives = 106/181 (58.56%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRL-LKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKL------KIT-GLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            K LPD++  NLD + +GINP + +      + G  N FWKC   S     E+ L    D  L +KY +GFTN+ +RAT  + DLS +EL      L EK+ KY+P I VFNG  IY+ +F R+L      K+  GLQ     D +  LF+MPS+S + A+FP+  DK+ F++KL+E+RD L
Sbjct:  165 KTLPDLLDHNLDYVIIGINPGLMAAYIGRWFPGPGNHFWKCLFLSGFT--EDQLNHMHDTTLPVKYKMGFTNMVARATPGSKDLSSKELREGGKILVEKLKKYKPLIAVFNGKCIYE-MFCRELFGKKPQKLEFGLQPHKIPDCDVALFLMPSSSARCAQFPRAQDKVHFYIKLRELRDQL 342
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Planmine SMEST
Match: SMESG000043196.1 (SMESG000043196.1)

HSP 1 Score: 249.21 bits (635), Expect = 2.972e-85
Identity = 122/125 (97.60%), Postives = 123/125 (98.40%), Query Frame = 3 
Query:  138 MDSEFLKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIF 512
            MDSEFLKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGN KEKIVKY+PKIVVFNGILIYKTI 
Sbjct:    1 MDSEFLKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNRKEKIVKYKPKIVVFNGILIYKTIL 125
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Planmine SMEST
Match: SMESG000067021.1 (SMESG000067021.1)

HSP 1 Score: 163.696 bits (413), Expect = 3.721e-46
Identity = 79/173 (45.66%), Postives = 113/173 (65.32%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            + LPD +KENLD++ VGINPS+ S    HHYAG  N FW C   + +VP   ++   DDYR++ YGIGFTN+CSR T  A ++S++E++     + EK+ KY+PKI VFNG  IY+     K    G Q  P   T+ I+FVMPS+S + A+ P+  DKL FF+ L+++RD++
Sbjct:  103 RTLPDYLKENLDLIVVGINPSMTSACVGHHYAGIGNHFWTCIAEAGLVP--ETVTCYDDYRMVDYGIGFTNVCSRPTKGAAEISRKEMKAGALVMLEKMRKYKPKIAVFNGKGIYEAFIGHKNFYMGKQPKPLDGTDIIVFVMPSSSARCAQLPRAEDKLPFFIALRKLRDHV 273
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Planmine SMEST
Match: SMESG000067021.1 (SMESG000067021.1)

HSP 1 Score: 163.696 bits (413), Expect = 4.375e-46
Identity = 79/173 (45.66%), Postives = 113/173 (65.32%), Query Frame = 3 
Query:  156 KILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            + LPD +KENLD++ VGINPS+ S    HHYAG  N FW C   + +VP   ++   DDYR++ YGIGFTN+CSR T  A ++S++E++     + EK+ KY+PKI VFNG  IY+     K    G Q  P   T+ I+FVMPS+S + A+ P+  DKL FF+ L+++RD++
Sbjct:  103 RTLPDYLKENLDLIVVGINPSMTSACVGHHYAGIGNHFWTCIAEAGLVP--ETVTCYDDYRMVDYGIGFTNVCSRPTKGAAEISRKEMKAGALVMLEKMRKYKPKIAVFNGKGIYEAFIGHKNFYMGKQPKPLDGTDIIVFVMPSSSARCAQLPRAEDKLPFFIALRKLRDHV 273
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Planmine SMEST
Match: SMESG000064938.1 (SMESG000064938.1)

HSP 1 Score: 156.762 bits (395), Expect = 4.286e-44
Identity = 80/172 (46.51%), Postives = 110/172 (63.95%), Query Frame = 3 
Query:  153 LKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNASKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRD 668
            L ILPD IKE+LD++ +G+NPS+ S +  H++AG  N FW C +   +VP    +   DD R+L Y IGFTN CSRAT  A DLSK+EL+  +  L  K+ ++ PKIVVFNG   Y+T  + K    G Q      TNS++FVMPS+S + A+ P+  DK+ FF  LK++RD
Sbjct:   13 LHILPDYIKEDLDMVVIGLNPSLTSAQIGHYFAGPGNHFWSCISEVGLVP--EPVTCYDDARMLDYSIGFTNACSRATKGAADLSKKELKDGMKLLLAKLQRFCPKIVVFNGKGTYETFVRHKHFGMGKQPNRLEGTNSVVFVMPSSSARCAQLPRAADKIPFFSALKDLRD 182
[Close]
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Planmine SMEST
Match: SMESG000029306.1 (SMESG000029306.1)

HSP 1 Score: 110.538 bits (275), Expect = 6.729e-29
Identity = 52/116 (44.83%), Postives = 78/116 (67.24%), Query Frame = 3 
Query:  327 DDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGNLKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMPSTSGKNAKFPKFNDKLIFFLKLKEIRDNL 674
            DD ++L YGIGF + C+R      +LS++E+++  G + EKI KY+PKIVVFNGI IY+     K    GLQ      T+S++FVMPS+S + A+ P+  DK+ FF+ LK++RD++
Sbjct:   10 DDTQMLDYGIGFISFCTRPNKGTTELSRKEMKIGAGLMVEKIKKYKPKIVVFNGIGIYEAFIGNKNFSMGLQPNKMEGTDSVIFVMPSSSARCAQLPRAEDKIPFFVSLKKLRDHM 125
The following BLAST results are available for this feature:
BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TDG2.083e-4143.55thymine DNA glycosylase [Source:HGNC Symbol;Acc:HG... [more]
TDG2.147e-4143.55thymine DNA glycosylase [Source:HGNC Symbol;Acc:HG... [more]
TDG4.348e-3243.14thymine DNA glycosylase [Source:HGNC Symbol;Acc:HG... [more]
TDG2.153e-2441.06thymine DNA glycosylase [Source:HGNC Symbol;Acc:HG... [more]
TDG4.405e-1946.74thymine DNA glycosylase [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Thd11.474e-3638.73gene:FBgn0026869 transcript:FBtr0333706[more]
Thd11.474e-3638.73gene:FBgn0026869 transcript:FBtr0345197[more]
Thd11.474e-3638.73gene:FBgn0026869 transcript:FBtr0089106[more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tdg.25.146e-3842.70thymine DNA glycosylase, tandem duplicate 2 [Sourc... [more]
tdg.25.794e-3842.70thymine DNA glycosylase, tandem duplicate 2 [Sourc... [more]
tdg.11.093e-3641.67thymine DNA glycosylase, tandem duplicate 1 [Sourc... [more]
tdg.11.093e-3641.67thymine DNA glycosylase, tandem duplicate 1 [Sourc... [more]
tdg.21.743e-1443.37thymine DNA glycosylase, tandem duplicate 2 [Sourc... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tdg2.186e-3942.22thymine DNA glycosylase [Source:NCBI gene;Acc:4484... [more]
tdg2.287e-3942.22thymine DNA glycosylase [Source:NCBI gene;Acc:4484... [more]
tdg2.935e-3942.22thymine DNA glycosylase [Source:NCBI gene;Acc:4484... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tdg1.028e-4143.55thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI... [more]
Tdg1.236e-4143.55thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI... [more]
Tdg5.836e-2843.05thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI... [more]
Tdg3.121e-1946.74thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI... [more]
Tdg1.455e-1747.62thymine DNA glycosylase [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P56581|TDG_MOUSE8.648e-4143.55G/T mismatch-specific thymine DNA glycosylase OS=M... [more]
sp|Q13569|TDG_HUMAN1.000e-4043.55G/T mismatch-specific thymine DNA glycosylase OS=H... [more]
sp|O59825|TDG_SCHPO3.378e-2430.70G/U mismatch-specific uracil DNA glycosylase OS=Sc... [more]
sp|P43343|MUG_SERMA1.749e-1831.51G/U mismatch-specific DNA glycosylase OS=Serratia ... [more]
sp|Q6D9D7|MUG_PECAS1.351e-1730.20G/U mismatch-specific DNA glycosylase OS=Pectobact... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3P6NTE11.970e-4847.37UDG domain-containing protein OS=Dibothriocephalus... [more]
A0A183PSR66.427e-4745.61UDG domain-containing protein OS=Schistosoma matth... [more]
A0A3R7CLJ31.058e-4646.20G/T mismatch-specific thymine DNA glycosylase (Fra... [more]
V4B7561.108e-4644.83UDG domain-containing protein (Fragment) OS=Lottia... [more]
A0A4E0RP311.175e-4649.12G/T mismatch-specific thymine DNA glycosylase OS=F... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
tdg.22.883e-3741.57G/T mismatch-specific thymine DNA glycosylase-like... [more]
tdg.12.204e-3641.71G/T mismatch-specific thymine DNA glycosylase [Sou... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tdg.22.176e-3740.88thymine DNA glycosylase, tandem duplicate 2 [Sourc... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO425591.699e-4444.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tdg.23.666e-3943.33G/T mismatch-specific thymine DNA glycosylase [Sou... [more]
tdg.14.119e-3540.56thymine DNA glycosylase [Source:NCBI gene;Acc:1011... [more]
tdg.19.604e-3541.44thymine DNA glycosylase [Source:NCBI gene;Acc:1011... [more]
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BLAST of G/T mismatch-specific thymine DNA glycosylase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000043196.12.972e-8597.60SMESG000043196.1[more]
SMESG000067021.13.721e-4645.66SMESG000067021.1[more]
SMESG000067021.14.375e-4645.66SMESG000067021.1[more]
SMESG000064938.14.286e-4446.51SMESG000064938.1[more]
SMESG000029306.16.729e-2944.83SMESG000029306.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030696 ID=SMED30030696|Name=G/T mismatch-specific thymine DNA glycosylase|organism=Schmidtea mediterranea sexual|type=transcript|length=703bp
CTCACACACATTTATGATAATGTTTTACACACGAATTTGGGGTAGACAAT
TTCACCCAAAGTAGAAAAGTAAGTGTGTAAAGTTTATTGGATTACTTGAA
TATAAATTAACGAATTTAAAATTTGTTGAATTCTAATATGGATTCCGAGT
TTCTTAAAATACTTCCAGATATAATTAAAGAGAACCTAGATATTTTATTT
GTTGGTATAAATCCAAGTATTGCGTCAATGAAAACGAGTCACCACTATGC
TGGGAAATCCAATAGCTTTTGGAAATGTTTTAATGCTTCAAAAATCGTGC
CTCTAGAAAATAGTCTAGGTTTTACAGACGATTACCGCCTTTTAAAGTAT
GGTATTGGATTTACAAATATTTGCAGTAGAGCTACAGTAACGGCTAATGA
TCTAAGTAAAGAAGAATTAGAAGTTTCAGTTGGAAATCTTAAAGAAAAAA
TTGTTAAATATAGACCAAAAATTGTAGTTTTCAATGGAATACTTATTTAT
AAAACAATTTTTAAACGGAAATTAAAAATTACCGGCTTACAAGAATTTCC
ATATGCAGACACGAATTCGATCTTGTTTGTTATGCCTTCGACCAGTGGTA
AAAACGCAAAATTTCCAAAATTTAACGACAAGCTGATTTTTTTCTTGAAG
TTGAAAGAAATTCGAGATAACCTATATAATAATTAATCATCCGTCTTGTT
TAT
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protein sequence of SMED30030696-orf-1

>SMED30030696-orf-1 ID=SMED30030696-orf-1|Name=SMED30030696-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=183bp
MDSEFLKILPDIIKENLDILFVGINPSIASMKTSHHYAGKSNSFWKCFNA
SKIVPLENSLGFTDDYRLLKYGIGFTNICSRATVTANDLSKEELEVSVGN
LKEKIVKYRPKIVVFNGILIYKTIFKRKLKITGLQEFPYADTNSILFVMP
STSGKNAKFPKFNDKLIFFLKLKEIRDNLYNN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0002089reproductive organ
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR005122Uracil-DNA_glycosylase-like
Vocabulary: biological process
TermDefinition
GO:0006281DNA repair
Vocabulary: molecular function
TermDefinition
GO:0019104DNA N-glycosylase activity