Pantothenate kinase 4
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030654 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Pantothenate kinase 4 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366]) HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0 Identity = 369/808 (45.67%), Postives = 481/808 (59.53%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F + FP+LLVNIGSG+SI+KVE+E F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA L ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769
BLAST of Pantothenate kinase 4 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366]) HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0 Identity = 369/808 (45.67%), Postives = 481/808 (59.53%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F + FP+LLVNIGSG+SI+KVE+E F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA L ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769
BLAST of Pantothenate kinase 4 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366]) HSP 1 Score: 614.764 bits (1584), Expect = 0.000e+0 Identity = 369/808 (45.67%), Postives = 481/808 (59.53%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F + FP+LLVNIGSG+SI+KVE+E F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA L ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 34 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 777
BLAST of Pantothenate kinase 4 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366]) HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0 Identity = 350/807 (43.37%), Postives = 456/807 (56.51%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER L FIKFE Y+ CL FI +++V N + K ++ TGGGA F+ + +D F F+ N I FP+LLVNIGSG+SI+KVE+E F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA L ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGA-----------------------------FVYQKDSDPEFRFQT----NHPHI-----FPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 730
BLAST of Pantothenate kinase 4 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366]) HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0 Identity = 350/807 (43.37%), Postives = 456/807 (56.51%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER L FIKFE Y+ CL FI +++V N + K ++ TGGGA F+ + +D F F+ N I FP+LLVNIGSG+SI+KVE+E F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA L ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGA-----------------------------FVYQKDSDPEFRFQT----NHPHI-----FPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 730
BLAST of Pantothenate kinase 4 vs. Ensembl Celegans
Match: pnk-4 (Pantothenate kinase [Source:UniProtKB/TrEMBL;Acc:Q18580]) HSP 1 Score: 371.703 bits (953), Expect = 2.345e-116 Identity = 268/800 (33.50%), Postives = 404/800 (50.50%), Query Frame = 2
Query: 146 VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFY--FEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFA--------AKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNV----PVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQ---SKILQLKSM-DWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQ 2491
+ + D VKIVY ++ C + K +E C I+ + L+F EN P D+ VT + ++++ K L+V + D L G FLL+NI E F F+E F ++ + FP+LL+NI +G+S++ VE E F R+GG+SIGGG+F G+ LI +E++ A G+ D+ ++DIYG + N+ +L+A+SF A+ D SK +A+ SLL I N+ QL+ + +E+ NV R+ F GF R MK +S + NYWS K+RA FLRHE Y +GA+L++F ++ + W E +GS + L + V E E F +T F +R T + F LL Q PD+ D D EAR +W++ + I Q + R+ ++ +++K + + + +G R +L+ + L++ GF D Y +K EN A+ +KI +LK+ D T V GLLAGNVFDWG+KE+V +M+ S+ G+ F A++ ++ RPWL D +D ++ K Y SVLIF DNSGFD+I+G++PFA E L GS VI+ ANT P++ND+T+ E+V L L + ++ + + +++ V GQ SPC+D R V + LN ++ DLVVIEGM RA+HTN +F CDSLK AVIK WLA+RLGG++FSVVFK+E
Sbjct: 20 ITHICFDACSKTVKIVYSSSVPLSHTTLECTRILSK----QSEDRIYC-IQVQYPDFPLILNFFGENC--PLLKGTTVDFV----VTASQNAEIEEVIRKVLDVELRHVDAFNGLVNGTSFLLRNIEAECFTYSFDESQEYEFQTLNNDSMFPYLLINIRTGVSVVLVEGENQFKRLGGSSIGGGSFLGLTELITGVSDIEEMMDRALQGSPDEFDIFIRDIYGDRASNFNMDPHLLAASFGRVTRGETVRRAENFDEQSKNNAILSLLRMILYNVSQLAYMLSEISNVKRVFFNGFLVRNRPIVMKTLSFACNYWSSGKLRAYFLRHENYTTGLGAFLENFPNA-----------------DLYWKEYCSGSTA------LGRFVPVE-PLETGFKTQT----------------------FALR---CTGFKAAPFALLVD-QDGKPDTIDFNKDEEARNFWIEILDKTINDITKFAIASQENCSNKEDLTNRAEDFQSDFVKTMDIIKEHHVAYGNSNARNMLEVREQILQEKGFDDIYVQKKHAENCTAIAELPRVLAKIDELKNTGDEKTVLEYVSRGLLAGNVFDWGAKEVVKMMN-SESGLT-FQTAIDHVENRPWLFDGFDSFYKKHKE-------YKSVLIFVDNSGFDYILGIIPFARELLRNGSRVIICANTSPALNDLTYREMVELAPELKNADSDLAKFIDSNQMMFVQTGQESPCMDARRVHQDLNETVKKFNTDLVVIEGMGRALHTNFNVQFKCDSLKAAVIKTQWLADRLGGKMFSVVFKHEH 749
BLAST of Pantothenate kinase 4 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7]) HSP 1 Score: 209.149 bits (531), Expect = 9.100e-60 Identity = 144/351 (41.03%), Postives = 205/351 (58.40%), Query Frame = 2
Query: 125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFG 1144
+TF + + ++DIGG+L+K+VY + + + KY D +R + F KF ++ FI N + + + + H TGGG+ K+ +++ K+L V + + DEM SL G FLL DE F Y + G N + I +PFLLVNIG+GISILKV+S S+ RVGG+S+GGGTF G+G L+ ++FDELL MA+ G++ NVD LV DIYGG + L L +LIA S F K H ED SLLL +SNNIGQ++ L+ N+ RI FGG+F R TM+ +S ++NYWSK ++ AL+L+HEGYLGA+G++L G
Sbjct: 59 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYFIRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFLDEDG 399
BLAST of Pantothenate kinase 4 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7]) HSP 1 Score: 209.149 bits (531), Expect = 9.100e-60 Identity = 144/351 (41.03%), Postives = 205/351 (58.40%), Query Frame = 2
Query: 125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFG 1144
+TF + + ++DIGG+L+K+VY + + + KY D +R + F KF ++ FI N + + + + H TGGG+ K+ +++ K+L V + + DEM SL G FLL DE F Y + G N + I +PFLLVNIG+GISILKV+S S+ RVGG+S+GGGTF G+G L+ ++FDELL MA+ G++ NVD LV DIYGG + L L +LIA S F K H ED SLLL +SNNIGQ++ L+ N+ RI FGG+F R TM+ +S ++NYWSK ++ AL+L+HEGYLGA+G++L G
Sbjct: 59 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYFIRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFLDEDG 399
BLAST of Pantothenate kinase 4 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7]) HSP 1 Score: 209.534 bits (532), Expect = 2.479e-59 Identity = 144/351 (41.03%), Postives = 205/351 (58.40%), Query Frame = 2
Query: 125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFG 1144
+TF + + ++DIGG+L+K+VY + + + KY D +R + F KF ++ FI N + + + + H TGGG+ K+ +++ K+L V + + DEM SL G FLL DE F Y + G N + I +PFLLVNIG+GISILKV+S S+ RVGG+S+GGGTF G+G L+ ++FDELL MA+ G++ NVD LV DIYGG + L L +LIA S F K H ED SLLL +SNNIGQ++ L+ N+ RI FGG+F R TM+ +S ++NYWSK ++ AL+L+HEGYLGA+G++L G
Sbjct: 105 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYFIRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFLDEDG 445
BLAST of Pantothenate kinase 4 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7]) HSP 1 Score: 142.51 bits (358), Expect = 2.066e-36 Identity = 114/287 (39.72%), Postives = 160/287 (55.75%), Query Frame = 2
Query: 125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQL 952
+TF + + ++DIGG+L+K+VY + + + KY D +R + F KF ++ FI N + + + + H TGGG+ K+ +++ K+L V + + DEM SL G FLL DE F Y + G N + I +PFLLVNIG+GISILKV+S S+ RVGG+S+GGGTF G+G L+ ++FDELL MA+ G++ NVD LV DIYGG + L L +LIA S F K H ED SLLL +SNNIGQ+
Sbjct: 105 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQI 381
BLAST of Pantothenate kinase 4 vs. Ensembl Fly
Match: CG5828 (gene:FBgn0031682 transcript:FBtr0079018) HSP 1 Score: 263.848 bits (673), Expect = 2.287e-80 Identity = 141/362 (38.95%), Postives = 220/362 (60.77%), Query Frame = 2
Query: 1433 LLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLD-DIPTLHG--VLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSM-DWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGE-LFSVVFKYEQFA 2497
LL P Y PD+ DL +D +A YW CF+ V + +SQ ++ TA R+ Q++ YL+ L + ++P G +L LL ++ LR+YGFTDP+ QK+ EN A+ + ++ +L ++ D +TR +++ G+LAGN+FDWG++ I ++ + D A+++++ RPWL+D D W +L +P + ++F DNSG D ++GV+PF L RG+ V+L AN+EP++NDVT E+ L+ + + ++ A +LL+ NGQ PCLD+R + + L I + + DL+VIEGM RA+HTNL A F C++LK+AVIKN WLA LGGE +F+VV K+E A
Sbjct: 6 LLPDPAVYQPDTLDLNTDGKAADYWFNCFRDMVAKFAKVAAKSQ-EEDHTATQRAEQFQAAYLQRLEEHQRNVPVNKGKVILGTSELLKLNETLLRRYGFTDPWLRQKRLENASAVARLKQRLQELDALADEDTRWTELVRGVLAGNMFDWGAQAISNILEQ--DSNFGLHSALDRIEKRPWLLDNLDSWLNRLKGEP-----HKCAVVFVDNSGVDVVLGVLPFVRGLLKRGTKVLLCANSEPALNDVTSEELKSLLDDCSRECEVLEQAWSKGQLLVYANGQTGPCLDMRTLPKELCDAIAANETDLLVIEGMGRALHTNLNARFGCETLKLAVIKNKWLAKYLGGEDMFAVVCKFEPAA 359
BLAST of Pantothenate kinase 4 vs. Ensembl Fly
Match: CG5828 (gene:FBgn0031682 transcript:FBtr0329981) HSP 1 Score: 263.848 bits (673), Expect = 2.287e-80 Identity = 141/362 (38.95%), Postives = 220/362 (60.77%), Query Frame = 2
Query: 1433 LLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLD-DIPTLHG--VLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSM-DWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGE-LFSVVFKYEQFA 2497
LL P Y PD+ DL +D +A YW CF+ V + +SQ ++ TA R+ Q++ YL+ L + ++P G +L LL ++ LR+YGFTDP+ QK+ EN A+ + ++ +L ++ D +TR +++ G+LAGN+FDWG++ I ++ + D A+++++ RPWL+D D W +L +P + ++F DNSG D ++GV+PF L RG+ V+L AN+EP++NDVT E+ L+ + + ++ A +LL+ NGQ PCLD+R + + L I + + DL+VIEGM RA+HTNL A F C++LK+AVIKN WLA LGGE +F+VV K+E A
Sbjct: 6 LLPDPAVYQPDTLDLNTDGKAADYWFNCFRDMVAKFAKVAAKSQ-EEDHTATQRAEQFQAAYLQRLEEHQRNVPVNKGKVILGTSELLKLNETLLRRYGFTDPWLRQKRLENASAVARLKQRLQELDALADEDTRWTELVRGVLAGNMFDWGAQAISNILEQ--DSNFGLHSALDRIEKRPWLLDNLDSWLNRLKGEP-----HKCAVVFVDNSGVDVVLGVLPFVRGLLKRGTKVLLCANSEPALNDVTSEELKSLLDDCSRECEVLEQAWSKGQLLVYANGQTGPCLDMRTLPKELCDAIAANETDLLVIEGMGRALHTNLNARFGCETLKLAVIKNKWLAKYLGGEDMFAVVCKFEPAA 359
BLAST of Pantothenate kinase 4 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0078190) HSP 1 Score: 175.637 bits (444), Expect = 1.103e-47 Identity = 125/369 (33.88%), Postives = 195/369 (52.85%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVY-----QTTKQFKRKVPVCEEV------SYKYVDSDAERNCLCFIKFETKYLSECLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFE--------EKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQ 1180
F MDIGG+L K+VY T + R+ + + + Y + L E + LHFI + N + + + + TGGGA KF+ ++N+ + K DE+++L +G +F + E +Y+E EK NFS PFPF+LVN+GSG+SIL V ++ R+ GTS+GGGTF G+ CL+ SF+E + +A+ G+ VD LVKDIYGG LP +L+ASSF S+ED ++ L+TI+NNIG ++ + A +DR++F G F R + +MK+++ ++ +WS ++ LFL HEGY GA+G L+ G+ + +N +E
Sbjct: 4 FGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGNFLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNFS-----QPFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQFNGELAAALNDGVEH 367
BLAST of Pantothenate kinase 4 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0078189) HSP 1 Score: 175.637 bits (444), Expect = 1.103e-47 Identity = 125/369 (33.88%), Postives = 195/369 (52.85%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVY-----QTTKQFKRKVPVCEEV------SYKYVDSDAERNCLCFIKFETKYLSECLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFE--------EKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQ 1180
F MDIGG+L K+VY T + R+ + + + Y + L E + LHFI + N + + + + TGGGA KF+ ++N+ + K DE+++L +G +F + E +Y+E EK NFS PFPF+LVN+GSG+SIL V ++ R+ GTS+GGGTF G+ CL+ SF+E + +A+ G+ VD LVKDIYGG LP +L+ASSF S+ED ++ L+TI+NNIG ++ + A +DR++F G F R + +MK+++ ++ +WS ++ LFL HEGY GA+G L+ G+ + +N +E
Sbjct: 4 FGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGNFLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNFS-----QPFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQFNGELAAALNDGVEH 367
BLAST of Pantothenate kinase 4 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0078186) HSP 1 Score: 175.637 bits (444), Expect = 1.267e-47 Identity = 125/369 (33.88%), Postives = 195/369 (52.85%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVY-----QTTKQFKRKVPVCEEV------SYKYVDSDAERNCLCFIKFETKYLSECLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFE--------EKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQ 1180
F MDIGG+L K+VY T + R+ + + + Y + L E + LHFI + N + + + + TGGGA KF+ ++N+ + K DE+++L +G +F + E +Y+E EK NFS PFPF+LVN+GSG+SIL V ++ R+ GTS+GGGTF G+ CL+ SF+E + +A+ G+ VD LVKDIYGG LP +L+ASSF S+ED ++ L+TI+NNIG ++ + A +DR++F G F R + +MK+++ ++ +WS ++ LFL HEGY GA+G L+ G+ + +N +E
Sbjct: 20 FGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGNFLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNFSQ-----PFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQFNGELAAALNDGVEH 383
BLAST of Pantothenate kinase 4 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592]) HSP 1 Score: 343.584 bits (880), Expect = 1.311e-108 Identity = 232/525 (44.19%), Postives = 301/525 (57.33%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFK----RKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIP 1645
E F NL+ A FA+DIGGSL K+ Y +T Q K R +VS++ D D L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + +DKEDEM L +GC F+LKNI E F + + + F + FP+LL+NIGSG+SI+KVESE F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG L L +LIASSF +A FSKED SLL ISN+IGQL+CL+A+L N+ R+ FGGFF RGH TM I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + ELN + R G+ F++ E++R + +L LL+ P +Y PD+ DLT D AR YWL CF+ + V SQKDQ + A+ R+ ++ + Y L L P
Sbjct: 24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKVSFQETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDKEFSKEDMAKSLLHMISNDIGQLACLYAKLHNLTRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSPELNPVQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLHDPTSYIPDTVDLTEDALARDYWLYCFEDALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQP 495
BLAST of Pantothenate kinase 4 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592]) HSP 1 Score: 343.584 bits (880), Expect = 1.311e-108 Identity = 232/525 (44.19%), Postives = 301/525 (57.33%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFK----RKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIP 1645
E F NL+ A FA+DIGGSL K+ Y +T Q K R +VS++ D D L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + +DKEDEM L +GC F+LKNI E F + + + F + FP+LL+NIGSG+SI+KVESE F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG L L +LIASSF +A FSKED SLL ISN+IGQL+CL+A+L N+ R+ FGGFF RGH TM I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + ELN + R G+ F++ E++R + +L LL+ P +Y PD+ DLT D AR YWL CF+ + V SQKDQ + A+ R+ ++ + Y L L P
Sbjct: 24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKVSFQETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDKEFSKEDMAKSLLHMISNDIGQLACLYAKLHNLTRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSPELNPVQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLHDPTSYIPDTVDLTEDALARDYWLYCFEDALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQP 495
BLAST of Pantothenate kinase 4 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592]) HSP 1 Score: 327.405 bits (838), Expect = 1.093e-103 Identity = 179/430 (41.63%), Postives = 251/430 (58.37%), Query Frame = 2
Query: 1208 SWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
SW ENYAGS+ S + ELN + R G+ F++ E++R + +L LL+ P +Y PD+ DLT D AR YWL CF+ + V SQKDQ + A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN+ A+K + + ++ + W RQF ++ GLLAGNVFDWG+K + ++ D F +A +LQ RPWL+D Y +W ++ P + L F DNSG D I+GV PF E L RG+ V+L++N+ P++NDVT SE+ IL + +A++ P I SA K +L LV NG SPCLDL + + L ++ DLV+IEGM RAIHTN A +C+SLK+AVIKN+WLA RLGG++FSVVFKYE
Sbjct: 6 SWGENYAGSSGLMSVSPELNPVQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLHDPTSYIPDTVDLTEDALARDYWLYCFEDALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKIKQKENDMALKYYLKVVKSVEELSWEQRQFALVKGLLAGNVFDWGAKAVSDVLET--DPEFGFEQAKQQLQERPWLVDAYSQWIERMKGPP-----HKCALFFVDNSGIDIILGVFPFIRELLLRGTEVVLASNSGPALNDVTNSELQILTERIAAMDPVIQSAFKEDRLALVQNGSSSPCLDLSRLDKVLATVVRERGTDLVIIEGMGRAIHTNYYAMLSCESLKLAVIKNSWLAERLGGKIFSVVFKYE 397
BLAST of Pantothenate kinase 4 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592]) HSP 1 Score: 203.371 bits (516), Expect = 1.057e-58 Identity = 138/277 (49.82%), Postives = 172/277 (62.09%), Query Frame = 2
Query: 170 GGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAE 970
GGSL K+ Y +T Q K + S K D D L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + +DKEDEM L +GC F+LKNI E F + + + F + FP+LL+NIGSG+SI+KVESE F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG L L +LIASSF +A FSKED SLL ISN+IGQL+CL+A+
Sbjct: 30 GGSLTKLAYYSTVQHKVAKVRSFDHSAKETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDKEFSKEDMAKSLLHMISNDIGQLACLYAK 298
BLAST of Pantothenate kinase 4 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592]) HSP 1 Score: 183.341 bits (464), Expect = 9.775e-52 Identity = 129/261 (49.43%), Postives = 161/261 (61.69%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAA 874
E F NL+ A FA+DIGGSL K+ Y +T Q K + S K D D L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + +DKEDEM L +GC F+LKNI E F + + + F + FP+LL+NIGSG+SI+KVESE F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG L L +LIASSF +A
Sbjct: 24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSA 276
BLAST of Pantothenate kinase 4 vs. Ensembl Xenopus
Match: ca1 (carbonic anhydrase I [Source:Xenbase;Acc:XB-GENE-957160]) HSP 1 Score: 615.535 bits (1586), Expect = 0.000e+0 Identity = 372/812 (45.81%), Postives = 495/812 (60.96%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDE--MESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNI-KTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCF----KGNVPVDIVYQSQ-KDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + DA+ L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + +DKEDE M L +GC F+LKNI E F + + + P F N FP+LLVNIGSG+SI+KVE+E F R+GG+SIGGGTFWG+G L+ K K FDELL +A+ G++ NVDMLVKDIYGG +IL L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+ N+ ++ FGGFF RGH TM IS S+N++SK +V+ALFLRHEGYLG IGA+LK E N SW ENYAGS+ +T D + + +TR G+ F++ E++R + +L LL P +Y PD+ DLT D AR+YWL CF +G + Q + KD +D AQ ++++ Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN+ A+K FQ I L ++ W +QF ++ GLLAGNVFDWG+K + VL S S+ G F EA KLQ RPWL+D Y+ W +L P + LIF DNSG D I+G+ PF E L+RG+ VIL+ N+ P++NDVT++E +I+ + +A++ I SAL++++L+LV G SPCLDL + +GL L++ DLV+IEGM RAIHTN A F C+SLK+AVIKN+WLA RL G++FSVVFKYE
Sbjct: 28 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTGKDADHEQLYEISVQEEITARLHFIKFENAYIEICLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLGLKVDKEDEDEMTCLIKGCNFVLKNIPHEAFVYVKHADPEFRFQTTHPNIFPYLLVNIGSGVSIVKVEAEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNLIASSFGKSATIDKDFSKEDMAKSLLHMISNDIGQLACLYAKQHNLSQVYFGGFFIRGHPVTMHTISYSINFFSKGEVQALFLRHEGYLGTIGAFLKG--------------AEQDNPNMYSWGENYAGSSGLMSTS------------PDIYPMQRTRSGT------------------FDMLEMDRLERQLVNLPLLSDPSSYVPDTVDLTEDAMAREYWLSCFEEALEGVAKRAVASQPEAKDATDRAQ----KFQQKYFNKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKVKQKENDIALKYFQRVIKSLDALGWEEKQFALVKGLLAGNVFDWGAKAVSEVLESNSEFG---FEEAKEKLQARPWLVDTYNDWIARLRGSP-----HKCALIFVDNSGIDIILGIFPFVRELLARGTEVILACNSGPALNDVTYNESLIVTECIAAMDTTIQSALQDERLILVQTGSSSPCLDLSRLDKGLATLVKERNTDLVIIEGMGRAIHTNYYASFQCESLKLAVIKNSWLAERLQGKIFSVVFKYE 771
BLAST of Pantothenate kinase 4 vs. Ensembl Xenopus
Match: ca1 (carbonic anhydrase I [Source:Xenbase;Acc:XB-GENE-957160]) HSP 1 Score: 582.793 bits (1501), Expect = 0.000e+0 Identity = 363/810 (44.81%), Postives = 486/810 (60.00%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNI-KTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCF----KGNVPVDIVYQSQ-KDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + DA+ L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + D EDEM L +GC F+LKNI E F + + + P F N FP+LLVNIGSG+SI+KVE+E F R+GG+SIGGGTFWG+G L+ K K FDELL +A+ G++ NVDMLVKDIYGG +IL L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+ N+ ++ FGGFF RGH TM IS S+N++SK +V+ALFLRHEGYLG IGA+LK E N SW ENYAGS+ +T D + + +TR G+ F++ E++R + +L LL P +Y PD+ DLT D AR+YWL CF +G + Q + KD +D AQ ++++ Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN+ A+K FQ I L ++ W +QF ++ GLLAGNVFDWG+K + VL S S+ G F EA KLQ ++ ++ P + LIF DNSG D I+G+ PF E L+RG+ VIL+ N+ P++NDVT++E +I+ + +A++ I SAL++++L+LV G SPCLDL + +GL L++ DLV+IEGM RAIHTN A F C+SLK+AVIKN+WLA RL G++FSVVFKYE
Sbjct: 27 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTGKDADHEQLYEISVQEEITARLHFIKFENAYIEICLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLGLKYD-EDEMTCLIKGCNFVLKNIPHEAFVYVKHADPEFRFQTTHPNIFPYLLVNIGSGVSIVKVEAEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNLIASSFGKSATIDKDFSKEDMAKSLLHMISNDIGQLACLYAKQHNLSQVYFGGFFIRGHPVTMHTISYSINFFSKGEVQALFLRHEGYLGTIGAFLKG--------------AEQDNPNMYSWGENYAGSSGLMSTS------------PDIYPMQRTRSGT------------------FDMLEMDRLERQLVNLPLLSDPSSYVPDTVDLTEDAMAREYWLSCFEEALEGVAKRAVASQPEAKDATDRAQ----KFQQKYFNKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKVKQKENDIALKYFQRVIKSLDALGWEEKQFALVKGLLAGNVFDWGAKAVSEVLESNSEFG---FEEAKEKLQGEL-------KYSPHFETRKHGSP-HKCALIFVDNSGIDIILGIFPFVRELLARGTEVILACNSGPALNDVTYNESLIVTECIAAMDTTIQSALQDERLILVQTGSSSPCLDLSRLDKGLATLVKERNTDLVIIEGMGRAIHTNYYASFQCESLKLAVIKNSWLAERLQGKIFSVVFKYE 764
BLAST of Pantothenate kinase 4 vs. Ensembl Xenopus
Match: ca1 (carbonic anhydrase I [Source:Xenbase;Acc:XB-GENE-957160]) HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0 Identity = 352/809 (43.51%), Postives = 473/809 (58.47%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNI-KTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFK----GNVPVDIVYQSQ-KDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + DA+ L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + D EDEM L +GC F+LKNI E F + + + P F N FP+LLVNIGSG+SI+KVE+E F R+GG+SIGGGTFWG+G L+ K K FDELL +A+ G++ NVDMLVKDIYGG +IL L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+ N+ ++ FGGFF RGH TM IS S+N++SK +V+ALFLRHEGYLG IGA+LK E N SW ENYAGS+ +T D + + +TR G+ F++ E++R + +L LL P +Y PD+ DLT D AR+YWL CF+ G + Q + KD +D AQ ++++ Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN+ A+K FQ I L ++ W +QF ++ GLLAGNVF ++ +++ I FS Q P + LIF DNSG D I+G+ PF E L+RG+ VIL+ N+ P++NDVT++E +I+ + +A++ I SAL++++L+LV G SPCLDL + +GL L++ DLV+IEGM RAIHTN A F C+SLK+AVIKN+WLA RL G++FSVVFKYE
Sbjct: 24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTGKDADHEQLYEISVQEEITARLHFIKFENAYIEICLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLGLKYD-EDEMTCLIKGCNFVLKNIPHEAFVYVKHADPEFRFQTTHPNIFPYLLVNIGSGVSIVKVEAEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNLIASSFGKSATIDKDFSKEDMAKSLLHMISNDIGQLACLYAKQHNLSQVYFGGFFIRGHPVTMHTISYSINFFSKGEVQALFLRHEGYLGTIGAFLKG--------------AEQDNPNMYSWGENYAGSSGLMSTSP------------DIYPMQRTRSGT------------------FDMLEMDRLERQLVNLPLLSDPSSYVPDTVDLTEDAMAREYWLSCFEEALEGVAKRAVASQPEAKDATDRAQ----KFQQKYFNKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKVKQKENDIALKYFQRVIKSLDALGWEEKQFALVKGLLAGNVFYILNQPCYLIL-------ISFS----LFQGSP----------------------HKCALIFVDNSGIDIILGIFPFVRELLARGTEVILACNSGPALNDVTYNESLIVTECIAAMDTTIQSALQDERLILVQTGSSSPCLDLSRLDKGLATLVKERNTDLVIIEGMGRAIHTNYYASFQCESLKLAVIKNSWLAERLQGKIFSVVFKYE 738
BLAST of Pantothenate kinase 4 vs. Ensembl Xenopus
Match: cidea (cell death inducing DFFA like effector a [Source:Xenbase;Acc:XB-GENE-953574]) HSP 1 Score: 177.178 bits (448), Expect = 1.448e-48 Identity = 133/341 (39.00%), Postives = 195/341 (57.18%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSF--MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSS---ICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHE 1102
F MDIGG+LVK+VY K + E + K Y+ S+ + + + E K L+ C LHFI F M K++ L TGGGA KF++ ++ + K DE++ L +G +++ N E +YFE + CL NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+ ++F+E L MA+ G+ NVD LVKDIYGG E +L + +ASSF + + D SKED + L+TI+NNIG ++ + A N+DR+IF G F R ++ +MK++S +++YWSK +++ALFL HE
Sbjct: 10 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHRFIQMGSEKNFSSLHTTLCATGGGAYKFEEDFRTIADLQLHKLDELDCLIQGLLYVDSVGFNGRPECYYFENPTDTEQCQKKPYCLDNPYPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFSLQGSAVASSFGHMMSKEKRDSISKEDLARATLVTITNNIGSIARMCALNENIDRVIFVGNFLRINMVSMKLLSYAMDYWSKGQLKALFLEHE 350
BLAST of Pantothenate kinase 4 vs. Ensembl Xenopus
Match: cidea (cell death inducing DFFA like effector a [Source:Xenbase;Acc:XB-GENE-953574]) HSP 1 Score: 177.563 bits (449), Expect = 1.540e-48 Identity = 133/341 (39.00%), Postives = 195/341 (57.18%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSF--MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSS---ICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHE 1102
F MDIGG+LVK+VY K + E + K Y+ S+ + + + E K L+ C LHFI F M K++ L TGGGA KF++ ++ + K DE++ L +G +++ N E +YFE + CL NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+ ++F+E L MA+ G+ NVD LVKDIYGG E +L + +ASSF + + D SKED + L+TI+NNIG ++ + A N+DR+IF G F R ++ +MK++S +++YWSK +++ALFL HE
Sbjct: 14 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHRFIQMGSEKNFSSLHTTLCATGGGAYKFEEDFRTIADLQLHKLDELDCLIQGLLYVDSVGFNGRPECYYFENPTDTEQCQKKPYCLDNPYPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFSLQGSAVASSFGHMMSKEKRDSISKEDLARATLVTITNNIGSIARMCALNENIDRVIFVGNFLRINMVSMKLLSYAMDYWSKGQLKALFLEHE 354
BLAST of Pantothenate kinase 4 vs. Ensembl Mouse
Match: Pank4 (pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2387466]) HSP 1 Score: 614.379 bits (1583), Expect = 0.000e+0 Identity = 367/807 (45.48%), Postives = 482/807 (59.73%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D E++ L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F N FP+LLVNIGSG+SI+KVE+E F +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+L +DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYA S+ +T E + R G+ F++ E++R + L LL P +Y PD+ DLT D AR+YWL CF+ + V SQ + D + R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN A+K FQS L S+ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y +W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+ +LLLV G SPCLDL + +GL L+ DLVVIEGM RAIHTN A C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDVEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLES--DPQFGFEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSSPCLDLSRLDKGLAVLVRERGADLVVIEGMGRAIHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 769
BLAST of Pantothenate kinase 4 vs. Ensembl Mouse
Match: Pank4 (pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2387466]) HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0 Identity = 370/855 (43.27%), Postives = 484/855 (56.61%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVS-----------------------------------------------RGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D E++ L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F N FP+LLVNIGSG+SI+KVE+E F +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+L +DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYA S+ +T E + R G+ F++ E++R + L LL P +Y PD+ DLT D AR+YWL CF+ + V SQ + D + R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN A+K FQS L S+ W RQ ++ GLLAGNVFDWG+K + VL S + G F EA KLQ RPWL+D Y +W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+ +LLLV G SPCLDL + +GL L+ DLVVIEGM RAIHTN A C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDVEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPQFG---FEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSSPCLDLSLCTSRTTTCMVLPFAMWVLWTKLKSLVEKCLSPLSILLACSVLSAKSRLDKGLAVLVRERGADLVVIEGMGRAIHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 816
BLAST of Pantothenate kinase 4 vs. Ensembl Mouse
Match: Pank4 (pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2387466]) HSP 1 Score: 374.4 bits (960), Expect = 9.626e-121 Identity = 230/513 (44.83%), Postives = 300/513 (58.48%), Query Frame = 2
Query: 467 KEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKL 1996
KED M L +GC F+LKNI E F +++ S P F N FP+LLVNIGSG+SI+KVE+E F +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+L +DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYA S+ +T E + R G+ F++ E++R + L LL P +Y PD+ DLT D AR+YWL CF+ + V SQ + D + R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN A+K FQS L S+ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y +W +L
Sbjct: 2 KEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVL--ESDPQFGFEEAKRKLQERPWLVDSYTKWLQRL 468
BLAST of Pantothenate kinase 4 vs. Ensembl Mouse
Match: Pank1 (pantothenate kinase 1 [Source:MGI Symbol;Acc:MGI:1922985]) HSP 1 Score: 192.2 bits (487), Expect = 1.130e-53 Identity = 136/354 (38.42%), Postives = 204/354 (57.63%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFIIENIVPPSF---MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSS---ICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSF 1141
F MDIGG+LVK+VY K + E + K Y+ S+ + + + E K L+ C LHFI M K++ L TGGGA KF++ ++ + K DE++ L +G +++ N E +YFE + P CL NP+P LLVN+GSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+ ++F+E L MA+ G+ NVD LVKDIYGG E L + +ASSF + + + SKED + L+TI+NNIG ++ + A N+DR++F G F R ++ +MK+++ ++++WSK +++ALFL HEGY GA+GA L+ F
Sbjct: 14 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELF 367
BLAST of Pantothenate kinase 4 vs. Ensembl Mouse
Match: Pank1 (pantothenate kinase 1 [Source:MGI Symbol;Acc:MGI:1922985]) HSP 1 Score: 192.2 bits (487), Expect = 5.520e-52 Identity = 136/354 (38.42%), Postives = 204/354 (57.63%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFIIENIVPPSF---MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSF 1141
F MDIGG+LVK+VY K + E + K Y+ S+ + + + E K L+ C LHFI M K++ L TGGGA KF++ ++ + K DE++ L +G +++ N E +YFE + P CL NP+P LLVN+GSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+ ++F+E L MA+ G+ NVD LVKDIYGG E L + +ASSF + + + SKED + L+TI+NNIG ++ + A N+DR++F G F R ++ +MK+++ ++++WSK +++ALFL HEGY GA+GA L+ F
Sbjct: 189 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELF 542
BLAST of Pantothenate kinase 4 vs. UniProt/SwissProt
Match: sp|Q4R4U1|PANK4_MACFA (4'-phosphopantetheine phosphatase OS=Macaca fascicularis OX=9541 GN=PANK4 PE=2 SV=2) HSP 1 Score: 620.542 bits (1599), Expect = 0.000e+0 Identity = 367/808 (45.42%), Postives = 481/808 (59.53%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER+ L F+KFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F + FP+LLVNIGSG+SI+KVE+E F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA L ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT E +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTERDHEPPYEISVQEEITARLHFVKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSTSPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVNLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDTLGWEERQLALVKGLLAGNVFDWGAKAVSDVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHGESLIVAERIAGMDPVVHSALREERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALCCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769
BLAST of Pantothenate kinase 4 vs. UniProt/SwissProt
Match: sp|Q9NVE7|PANK4_HUMAN (4'-phosphopantetheine phosphatase OS=Homo sapiens OX=9606 GN=PANK4 PE=1 SV=1) HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0 Identity = 369/808 (45.67%), Postives = 481/808 (59.53%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F + FP+LLVNIGSG+SI+KVE+E F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA L ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769
BLAST of Pantothenate kinase 4 vs. UniProt/SwissProt
Match: sp|Q923S8|PANK4_RAT (4'-phosphopantetheine phosphatase OS=Rattus norvegicus OX=10116 GN=Pank4 PE=1 SV=1) HSP 1 Score: 614.379 bits (1583), Expect = 0.000e+0 Identity = 367/807 (45.48%), Postives = 482/807 (59.73%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + DAE++ L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F N FP+LLVNIGSG+SI+KVE+E F +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+L +DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYA S+ +T E + R G+ F++ E++R + L LL P +Y PD+ DLT D AR+YWL CF+ + V SQ + D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN A+K FQS L S+ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y +W +L P + LIF DNSG D I+GV PF E L RG VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+ +LLLV G PCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDAEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTAP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESVDAAE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLES--DPQFGFEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLCRGIEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSPPCLDLSRLDKGLAVLVRERGADLVVIEGMGRAVHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 769
BLAST of Pantothenate kinase 4 vs. UniProt/SwissProt
Match: sp|Q5R5F8|PANK4_PONAB (4'-phosphopantetheine phosphatase OS=Pongo abelii OX=9601 GN=PANK4 PE=2 SV=1) HSP 1 Score: 614.379 bits (1583), Expect = 0.000e+0 Identity = 366/808 (45.30%), Postives = 479/808 (59.28%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D ER+ L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F + FP+LLVNIGSG+SI+KVE+ F VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVD LV+D+YGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CLHA ++DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + EL A + R G+ F++ E++R + L LL P +Y PD+ DLT D ARKYWL CF+ + V SQ D D A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN A++ F + L ++ W RQ ++ GLLAGNVFDWG+K + ++ D F EA KLQ RPWL+D Y W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV G SPCLDL + +GL L+ DLVVIEGM RA+HTN A C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTERDHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETGDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDTLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARPHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSTSPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVNLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSDVL--ESDPCFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALREERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769
BLAST of Pantothenate kinase 4 vs. UniProt/SwissProt
Match: sp|Q80YV4|PANK4_MOUSE (4'-phosphopantetheine phosphatase OS=Mus musculus OX=10090 GN=Pank4 PE=1 SV=2) HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0 Identity = 370/855 (43.27%), Postives = 484/855 (56.61%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVS-----------------------------------------------RGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + D E++ L FIKFE Y+ CL FI +++V N + K ++ TGGGA KFKDL+ +KL + +DKED M L +GC F+LKNI E F +++ S P F N FP+LLVNIGSG+SI+KVE+E F +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L NLIASSF +A FSKED SLL ISN+IGQL+CL+A+L +DR+ FGGFF RGH TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK E N SW ENYA S+ +T E + R G+ F++ E++R + L LL P +Y PD+ DLT D AR+YWL CF+ + V SQ + D + R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K+KEN A+K FQS L S+ W RQ ++ GLLAGNVFDWG+K + VL S + G F EA KLQ RPWL+D Y +W +L P + LIF DNSG D I+GV PF E L RG+ VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+ +LLLV G SPCLDL + +GL L+ DLVVIEGM RAIHTN A C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct: 26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDVEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPQFG---FEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSSPCLDLSLCTSRTTTCMVLPFAMWVLWTKLKSLVEKCLSPLSILLACSVLSAKSRLDKGLAVLVRERGADLVVIEGMGRAIHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 816
BLAST of Pantothenate kinase 4 vs. TrEMBL
Match: A0A4E0RZE3 (Type II pantothenate kinase OS=Fasciola hepatica OX=6192 GN=D915_001131 PE=4 SV=1) HSP 1 Score: 682.945 bits (1761), Expect = 0.000e+0 Identity = 388/854 (45.43%), Postives = 528/854 (61.83%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVS-----------YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPP-----SFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSA----------------------------SFSNTKELNKAVIEELT-----FEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERT-------------------DDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVY--QSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKD---GIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKY 2485
FA+DIGGSL K+ Y+ T ++KR VP + Y Y + + E +C IKFET+ + ECL FI ENI+ + + + + +P +KVTGGGA +FKDL+++ L V ++KEDEME L RGCIF+L+NI DE+F++++ + P F S CL++ FPFLLVNIGSG+SILKVES S++RVGGTSIGGGTFWGIG +++ GK SFD+LL +A G++ VDMLV+DIYGG + L ++IASSF AA+ P DA+ SLL+T+SNNIGQL+CL+A+ N+ RI+FGGFF RGH TM++I+ +VN+WS RALFLRHEGYLGA+GA++K+ +++ + N + W ENY S S S ELN+ + ++ +ED+ ++ + S+ + + A + E+R RT D LE F L SP TY PD+WDLT DTEAR YWL C K V + +SQ D A RS QY + Y+ YL +L P+ GVLTVRCLL A Q+FLR++GF D + QKK EN A+ ++ L ++ W+ RQF + GLLAGNVFDWG+ E+V +++ G+ + + K+ PRPWLID YD+W +S P+ Y VLIFCDNSG D ++GV+PFALE +SRGS VIL+AN+ P+INDVT+ E+ IL++ ++S + AL + +LL+ NGQ SPCLDLR + L +L++ VDLVVIEGM RAIHTNL A F DSLK+AVIKNAWLA RLGG+L+ VVFK+
Sbjct: 39 FALDIGGSLAKLAYERTYRYKRSVPCPLDKPVPDNGLPPFTFYDYQEREHEGRKVCLIKFETRQIEECLEFIRENILQADAADATQLGDTETSRPAIKVTGGGAYRFKDLITRTLGVELNKEDEMECLIRGCIFMLRNIPDELFFYDKHATPAHVFVSDCLVDTFPFLLVNIGSGVSILKVESPTSYSRVGGTSIGGGTFWGIGSILSGGKCSFDQLLRLADQGDHRKVDMLVRDIYGGDYSAMGLQGDVIASSFGLAARSPEQPRCLADAVKSLLITVSNNIGQLACLYAKQHNLTRILFGGFFIRGHGLTMEVITYAVNFWSAGAYRALFLRHEGYLGAMGAFVKA-----------LDEWSSTNEPKTVWAENYVSSTRNACTMAEECILRSRQNSMASSQEFRGDSSSELTELNRGLSASMSAVPTEYEDTAHLSPGEPHLSMNSMQ--RVINSADLSSEIRLTSRTTVLKRPSLDTSYCELDRMMDFSLEPFPFLESPTTYVPDTWDLTQDTEARTYWLDCLKDGVERHRIKAEESQIDSMPDAAERSKQYADRYISYLQELGQNPSSCGVLTVRCLLSAQQHFLREFGFGDAFCRQKKLENRSALVSLPKRLNDLAALPWSERQFALASGLLAGNVFDWGAAEMVRFFAEAPTNSFGVPEMEATLAKIPPRPWLIDDYDKWIEAIS---PDRRPYRCVLIFCDNSGPDVLLGVLPFALEFISRGSKVILAANSAPAINDVTYQELDILLRLISSHVHVVAHALSSGRLLVAENGQTSPCLDLRLTASSLAHLVKREGVDLVVIEGMGRAIHTNLYARFRVDSLKVAVIKNAWLARRLGGQLYGVVFKF 876
BLAST of Pantothenate kinase 4 vs. TrEMBL
Match: A0A504YP63 (Type II pantothenate kinase OS=Fasciola gigantica OX=46835 GN=FGIG_07084 PE=4 SV=1) HSP 1 Score: 680.633 bits (1755), Expect = 0.000e+0 Identity = 390/852 (45.77%), Postives = 530/852 (62.21%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVS-----------YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPP-----SFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSA-----------------SFSNTKELNKAVIEELT----------------FED--SFNIKTRHGSIKS--KSLDDINISSKALIGFEVRELERT-------------DDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVY--QSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKD---GIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKY 2485
FA+DIGGSL K+ Y+ T ++KR VP + Y Y + + E +C IKFET+ + ECL FI ENI+ + + + + +P +KVTGGGA +FKDL+++ L V ++KEDEME L RGCIF+L+NI DE+FY+++ + P F S CL++ FPFLLVNIGSG+SILKVES S++RVGGTSIGGGTFWGIG +++ GK SFD+LL +A G++ VDMLV+DIYGG + L ++IASSF AA+ P DA+ SLL+T+SNNIGQL+CL+A+ N+ RI+FGGFF RGH TM++I+ +VN+WS RALFLRHEGYLGA+GA++K+ +++ + N + W ENY S S ++++E ELT +ED + H S+ S + ++ ++SS+ + L+R+ D LE F L SP TY PD+WDLT DTEAR YWL C K V + +SQ D A RS QY + Y+ YL +L P+ GVLTVRCLL A Q+FLR++GF D + QKK EN A+ ++ L ++ W+ RQF + GLLAGNVFDWG+ E+V +++ G+ + + K+ PRPWLID YD+W +S P Y VLIFCDNSG D ++GV+PFALE +SRGS VIL+AN+ P+INDVT+ E+ IL++ ++S + AL + +LL+ NGQ SPCLDLR + L +L++ VDLVVIEGM RAIHTNL A F DSLK+AVIKNAWLA RLGG+L+ VVFK+
Sbjct: 39 FALDIGGSLAKLAYERTYRYKRSVPCPLDKPVPDNGLPPFTFYDYQEREHEGRKVCLIKFETRQIEECLEFIRENILQADAADATQLGDTETSRPAIKVTGGGAYRFKDLITRTLGVELNKEDEMECLIRGCIFMLRNIPDELFYYDKHATPAHVFVSDCLVDTFPFLLVNIGSGVSILKVESPTSYSRVGGTSIGGGTFWGIGSILSGGKCSFDQLLRLADQGDHRKVDMLVRDIYGGDYSAMGLQGDVIASSFGLAARSPEQPRCLADAVKSLLITVSNNIGQLACLYAKQHNLTRILFGGFFIRGHGLTMEVITYAVNFWSAGAYRALFLRHEGYLGAMGAFVKA-----------LDEWSSTNEPKTVWAENYVSSTRNACTMAEECILRSRQNSMASSQEFRGDSSNELTELNRGLSASMSAVPTEYEDIARLSPGEPHLSMNSMQRVINSADLSSEIRLTSRTTVLKRSSLDTSYCELDRMMDFSLEPFPFLESPTTYVPDTWDLTQDTEARTYWLDCLKDGVERHRIKAEESQIDSMPDAAERSKQYADRYISYLQELGQNPSSCGVLTVRCLLSAQQHFLREFGFGDAFCRQKKLENRSALVSLPKRLNDLAALPWSERQFALASGLLAGNVFDWGAAEMVRFFAEAPTNSFGVPEMEATLAKIPPRPWLIDDYDKWIEAIS---PGRRPYRCVLIFCDNSGPDVLLGVLPFALEFISRGSKVILAANSAPAINDVTYQELDILLRLISSHVHVVAHALSSGRLLVAENGQTSPCLDLRLTASSLAHLVKREGVDLVVIEGMGRAIHTNLYARFRVDSLKVAVIKNAWLARRLGGQLYGVVFKF 876
BLAST of Pantothenate kinase 4 vs. TrEMBL
Match: G4VQ30 (Putative pantothenate kinase OS=Schistosoma mansoni OX=6183 GN=Smp_064750.1 PE=4 SV=1) HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0 Identity = 384/829 (46.32%), Postives = 537/829 (64.78%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVP--VCEEVS--------YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENY---AGSASFSNTK---------------ELNKAVIEELTFEDSFNIKTR--HGSIKSKSLDDINISSKALIGFEVR---------ELERT-DDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDT---AQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMS---KSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLS-SKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
FA+DIGGSL K+VY+ +++R VP C+ VS Y+Y + + E LCF+KFETK + ECL FI+ NI +++ K +KVTGGGA ++++L+ KL V +DKEDEM+ L RGC+F+L+NI DE+FY+++ + P F CL++ FPFLLVN+GSG+S LKVES S+ RVGGTSIGGGTFWG+G L++ GK +FDELL MA G++ +VDMLV+DIYGG E L L ++IASSF AA+ P D + SLL+T+SNNIGQL+CL+A+ ++ RIIFGG+F RGH TM++I+ +V +WS + +ALFLRHEGYLGA+GA+LK+ + N+S E+ + W ENY +G+ FS+ + +K +L +S + H I K+ + ++S ++ + EL+R LE+F LL SP Y+PD+WDLT D EAR YWL CF+ + ++++ QSDT A RS Q+ E Y ++L +L P+ HGVLTVRCLL A Q+FLR+YGF D + +QK+ EN A+ ++ +L +DW+ RQ +I GLLAGN+FDWG+ E + + K+K G DF ++K+Q RPWL+D YD W ++S S P Y +LIFCDNSG D I+GV+PFA+E LSRG VI++AN+ P+IND+T+ E+ +L+ +AS P I +L N +L+L NGQ SPCLD R ++ L L E +VDL+VIEGM RAIH NL ++FT D+LKIAVIKN+WLA RLGG+L+ V+FK+E
Sbjct: 26 FALDIGGSLAKLVYKRVFRYRRSVPQQCCKSVSENEIPFDFYEYTEHEDEGQKLCFMKFETKNIEECLDFILFNITHQGTLSKKTINK--IKVTGGGAYRYRELICSKLGVELDKEDEMDCLVRGCVFMLRNIPDELFYYDKHATPAHVFVPNCLVSTFPFLLVNVGSGVSFLKVESPTSYQRVGGTSIGGGTFWGLGTLLSGGKFTFDELLEMADSGDHRHVDMLVRDIYGGAYEALGLSGDVIASSFGLAARHPEQPRVLGDMVKSLLITVSNNIGQLACLYAKQHSLTRIIFGGYFIRGHGLTMEVITYAVRFWSGGEYKALFLRHEGYLGAVGAFLKACTN-----NNSTER-------KALWSENYVVSSGNTPFSDIPFESKLYATNHSKGEIDFSKVSSHDLPIVNSIGKVSNPNHSIIAQKAEESNSVSKRSSKSTSQKHEISKLPNFELDRVFTHSLEMFHLLESPANYSPDTWDLTHDEEARIYWLGCFESCIEYHRA-KAEESQSDTLSDASDRSHQFAERYKRFLRELSADPSGHGVLTVRCLLSAQQHFLREYGFGDVFCLQKRFENRAALSALTDRLSELSKLDWSNRQLSLIEGLLAGNMFDWGAAEAIQFLKEAPKNKFGAADFHAILDKVQSRPWLVDNYDNWINRISVSGSP----YRCILIFCDNSGADIILGVLPFAMEFLSRGCKVIMTANSSPAINDITYQELELLLHMIASFEPLIAESLNNGQLMLAENGQTSPCLDFRLLASSLVQLAEREQVDLIVIEGMGRAIHCNLNSKFTVDTLKIAVIKNSWLARRLGGQLYGVIFKFE 835
BLAST of Pantothenate kinase 4 vs. TrEMBL
Match: A0A5K3EWZ9 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 672.544 bits (1734), Expect = 0.000e+0 Identity = 384/850 (45.18%), Postives = 544/850 (64.00%), Query Frame = 2
Query: 62 TVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFK-------------RKVPVCEEVS-YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKD-YKPHLKVTGGGATKF-KDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSS-WIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDT----AQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKD---GIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLS 2527
T +P + ++ ++ K ++ A FA+DIGGSL K+ YQ T ++K R+ VC Y Y + + E + LCF+KFET+ + CL FI ++P S+ + ++D + +VTGGGA K+ ++L V I++EDEM SL GC FLL+NI DEVF +++++ P F S C++N +PFLLVNIGSG+S LKVE++ S+ RVGGTS+GGGTFWGIG L+A G+ SFDELL +A G++ VDMLVKDIYGG E L LP ++IASSF AA+ P + D + +LL+ +SNNIGQL+CL+A V RI+FGGFF RGH TM++IS +VNYWS+ +++A+FLRHEGYLGA+GA++KS + +++ E E S W E+YA A+I GSI + S N AL FE+ L D LE F LL S Y PD+WDLT D +AR YWL CFK V + ++++ Q+++ ++ R+ Q+ E Y+++L++L D P+ G+LTVRC+L+A Q+ LR++GF D + +QK+ EN +A+ F S + +L ++W RQ + G+L GN+FDWG+ E V +S+D G+ F +A+ KLQPRPWL+D + RW ++ +P + P H VL+FCDNSG D I+GV+PF +ECL GS VIL+AN+ P+INDVT+ E++ L+ A L P + +AL N KL+ V NGQ SPCLDLR S L +L++ KVDL+VIEGM RA+HTNL A F D LK+AVIKN+WLA RLGG+LFSV+F+YE+++ ++L LS
Sbjct: 5 TYAPPIDISSFAELVEEENQKHPHKIVECA-FALDIGGSLAKLAYQHTFRYKVCVPKELSDPDSKRRTSVCGPFEFYDYREHEYEGHKLCFVKFETRLIDSCLDFIRSTVLP-SYSDVDRDTIRLVGRVTGGGAFKYMSNILETLSGVEIEREDEMSSLVSGCTFLLRNIPDEVFIYDKRAMPAQIFLSSCMVNTYPFLLVNIGSGVSFLKVEADASYHRVGGTSLGGGTFWGIGSLLAGGQMSFDELLALADKGDHRQVDMLVKDIYGGAYESLGLPGDVIASSFGLAARRPNETRRPADMVKALLVAVSNNIGQLACLYAHQNGVRRILFGGFFIRGHRLTMEVISFAVNYWSQGEMKAMFLRHEGYLGAVGAFMKSRQQQETG-HTNGEAGEGVGKHTSKRWAESYA------------TALIS-------------RGSIPAFS----NAEGLALSEFELEHL--GDMSLEPFPLLLSSADYVPDTWDLTQDYKARVYWLGCFKQGVE-RLRRKAEESQAESDPHGSKQRARQFAERYVQFLSELSDRPSGRGILTVRCILEAQQHLLREFGFPDAFCVQKRAENSWALSCFPSIMERLGELNWEERQMALAQGVLTGNIFDWGASEAVRFFMQSQDSVEGMASFEKALAKLQPRPWLVDDFARWIERIR-RPDDRP--HCVLVFCDNSGADLILGVLPFVVECLDWGSKVILTANSVPAINDVTYRELLFLLNEAAGLEPRLQTALANGKLMCVDNGQSSPCLDLRQTSHNLVHLVKQEKVDLIVIEGMGRAVHTNLYARFCVDCLKVAVIKNSWLACRLGGDLFSVIFRYEEYS-NERLPMGLS 815
BLAST of Pantothenate kinase 4 vs. TrEMBL
Match: A0A0X3PQH0 (DUF89 domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR92302 PE=4 SV=1) HSP 1 Score: 666.766 bits (1719), Expect = 0.000e+0 Identity = 371/790 (46.96%), Postives = 512/790 (64.81%), Query Frame = 2
Query: 248 YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKL-NVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIA-KGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKS-------FGDSTSPINSSIEQIEAYNIMNSSWIENYA---GSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIG---FEVRELERTDD----------------RLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDT---AQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSK---DGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFA 2497
Y Y + + E + LCFIKFET+++ CL FI +NI+P NK K +VTGGGA KF + ++ KL + I++EDEMESL RGC FLL+NI DEVF +++++ P F S C+++ +PFLLVNIGSG+S LKVES +++RVGGTS+GGGTFWGIG L + G SFDELL +A GN++ VDMLV+DIYGG E L L + IASSF AA+ P + D + +LL+ +SNNIGQL+CL+A L NV RI+FGGFF RGH TM++IS +V YWS+ K++A+FLRHEGYLGA+GA++K+ G STS S + ++++ S Y S+S + + + F + N + + + DD + + K L F + RT D L F LL SP Y PD+WDLT DT+AR YWL+CF+ I ++++ QSDT A+ RS Q+ + Y +L++L D P+ G+LTVRC+L+A Q+FLRK GF D + QKK EN +A+ F + +LK++DW+ RQ + G+LAGN+FDWG+ E V +S+ DG+ F + NK+ PRPWL+D +DRW +++ + E H VLIFCDNSG D I+GV+PFA+ECL G VIL+AN++P+INDVT+ E++ L+ +A L + +AL +++L+ V NGQ SPCLDLR VS+ L L+ KVDL+V+EGM RA+HTNL A F D LKIAVIKN+WLA LGG LFSV+FKYE ++
Sbjct: 10 YDYREHEYEGHKLCFIKFETRFIEACLDFIRDNIMPDVV---NKHQKLVGRVTGGGAFKFLNTITTKLPGITIEREDEMESLVRGCAFLLRNIPDEVFTYDKRAEPAHIFLSSCMVDTYPFLLVNIGSGVSFLKVESGGTYSRVGGTSLGGGTFWGIGALFSGAGLSFDELLDLADQGNHLQVDMLVRDIYGGAYESLGLAGDTIASSFGLAARRPEEARRPADLIKALLIAVSNNIGQLACLYARLNNVQRILFGGFFIRGHALTMEVISFAVRYWSQGKMKAMFLRHEGYLGAVGAFMKNRMQGNSLAGSSTSWSESKVAGAPSFSVPGSGRRSIYPIQPHSSSSGQVRSPSDVFLSNTAFSGAAN--SLESETATDAPDDDSSTEKQLTPGPRFSLESNPRTLDFSTEWSAFELEHVVGVSLTTFPLLLSPADYVPDTWDLTQDTKARAYWLECFRQGAE-RIRQKAEESQSDTKSDAKARSQQFADLYFAFLSELADYPSGRGILTVRCILEAQQHFLRKLGFPDAFCHQKKLENSWALSFFPGMMERLKALDWSERQVALARGILAGNIFDWGASEAVRFFMQSQNSVDGMASFEQTQNKIPPRPWLMDDFDRWIQRIAVR---ERRPHCVLIFCDNSGADLILGVLPFAIECLDWGCKVILTANSDPAINDVTYPELLFLMNQVAELDERLTAALNSRRLICVDNGQNSPCLDLRRVSQNLVKLVNDEKVDLIVLEGMGRAVHTNLYARFCVDCLKIAVIKNSWLAGHLGGNLFSVIFKYEHYS 790
BLAST of Pantothenate kinase 4 vs. Ensembl Cavefish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:NCBI gene;Acc:103021954]) HSP 1 Score: 606.675 bits (1563), Expect = 0.000e+0 Identity = 360/806 (44.67%), Postives = 488/806 (60.55%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFK-RKVPVCEEVSYKYV-DSDAE-----------RNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIG-FEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
E F NL+ A FA+DIGGSL K+ Y +T Q K KV + + V ++D E L FIKFE Y+ CL FI +++V N + K +K TGGGA KFKDL+ KKL + +DKEDEM L +GC F+LKNI E F + + + F + FP+LLVNIGSG+SI+KVESE F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG L L +LIASSF +A FS+ED SLL ISN+IGQL+CL+A L N++R+ FGGFF RGH TM I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ + D+N +A G F++ E++R + +L LL P +Y PD+ DLT D AR+YWL CF+ + V SQKDQ + A+ R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN+ A+K +Q + L+ + W RQF ++ G+LAGNVFDWG+K + ++ D F +A +LQ RPWL+D Y++W +L P + L F DNSG D I+GV PF E L RG+ V+L++N+ P++NDVT SE+ I+ + +A++ P I +A+K ++L+LV +G SPCLDL + + L ++ DLV+IEGM RAIHTN A +C+SLK+AVIKN+WLA RLGG++FSVVFKYE
Sbjct: 24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHTAKAGVQEADGEPLYEISVQEEITARLHFIKFENTYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMSCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTRPDIFPYLLVNIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATADKEFSQEDMAKSLLHMISNDIGQLACLYARLHNLNRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSP------------------------------DLNPMQRARSGTFDMLEMDRLERQLVNLPLLQDPSSYIPDTVDLTEDALAREYWLYCFEEALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKIKQRENDMALKYYQKVVRSLEELSWEQRQFALVRGILAGNVFDWGAKAVSDVL--ESDPEFGFEQAKQQLQERPWLVDAYNQWVERLKGPP-----HKCALFFVDNSGMDIILGVFPFVRELLLRGTEVVLASNSGPALNDVTNSELQIVTERIAAMDPVIQTAVKEERLILVQSGSSSPCLDLSRLDKVLATVVRERGTDLVIIEGMGRAIHTNYYAMLSCESLKLAVIKNSWLAERLGGKIFSVVFKYE 769
BLAST of Pantothenate kinase 4 vs. Ensembl Cavefish
Match: pank1b (pantothenate kinase 1 [Source:NCBI gene;Acc:103047703]) HSP 1 Score: 190.66 bits (483), Expect = 1.836e-52 Identity = 137/352 (38.92%), Postives = 199/352 (56.53%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC------LCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
F MDIGG+LVK+VY K + E S K + N + + E K L+ C LHFI SF+ +D L TGGGA KF+D N+ + K DE++ L +G +++ N E ++F+ S P CL NPFP LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+ ++F+E L MA+ G+ NVD LVKDIYGG E L + +ASSF + + D SKED + L+TI+NNIG ++ + A ++R++F G F R + + K+++ ++++WSK +++ALFL HEGY GA+GA+L+
Sbjct: 92 FGMDIGGTLVKLVYFEPKDITAEEEQEEVESLKSIRRYLTSNVAYGDTGIRDVHLELKNLTMCGRTGNLHFIRFPTHDMHSFIQMGRDKNFSSLHTTLCATGGGAYKFEDDFRTVANLELQKLDELDCLIQGLLYVDSVGFNGHPECYFFQNPSDPENCVKQPCCLDNPFPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGHMMSKERRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLKALFLEHEGYFGAVGAFLE 443
BLAST of Pantothenate kinase 4 vs. Ensembl Cavefish
Match: pank2 (pantothenate kinase 2 [Source:NCBI gene;Acc:103044193]) HSP 1 Score: 189.504 bits (480), Expect = 3.650e-52 Identity = 136/365 (37.26%), Postives = 197/365 (53.97%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSD---------------------AERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIA---DEVFYFEEKSGP---NFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
F MDIGG+LVK+VY K + E S K Y+ S + L FI+F T+ L P+F+ +D L TGGGA KF+ ++ + K DE++ L +G +++ +A E +Y+E + P + L NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+ +F+E L MAS G VD LV+DIYGG E LP +ASSF + D SKED + L+TI+NNIG ++ + A N++R++F G F R + +MK+++ +++YWSK +++ALFLRHEGY GA+GA L+
Sbjct: 82 FGMDIGGTLVKLVYFEPKDITAEEEQEEVESLKSIRHYLTSHTAYGKTGIRDVHLELPDLILWGRKGSLHFIRFPTQEL-------------PAFLQMGRDKHFSSLHTTLCATGGGAYKFEADFRTMADLQLLKLDELDCLIKGVLYIDSVVARGPPECYYYENPTHPENCQQKAYNLENPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALEMASRGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMCKEKRDSVSKEDLARATLVTITNNIGSITRMCALNENIERVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLRHEGYFGAVGALLE 433
BLAST of Pantothenate kinase 4 vs. Ensembl Cavefish
Match: pank1a (pantothenate kinase 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2846]) HSP 1 Score: 158.688 bits (400), Expect = 2.358e-42 Identity = 123/358 (34.36%), Postives = 185/358 (51.68%), Query Frame = 2
Query: 161 MDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFS---SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSP 1159
MDIGG+LVK+VY K + E + K Y+ S+ + + + E + L C LHFI F+ +D L TGGGA KF++ ++ + K DE++ L G +++ N E +YFE S + CL NPFP LLVNIGSG+SIL V S T +G CL+ ++F+E L MAS G+ N D LV+DIYGG + L + +ASSF + + D SKED + L+TI+NNIG ++ + A ++R++F G F R + + K+++ ++++WS+ ++RALFL HEGY GA+GA+L+ P
Sbjct: 1 MDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRRYLTSNTAYGKTGVRDVHLELRNLRICGRTGTLHFIRFPTAAMHRFIQMGRDKNFSSLHTTLCATGGGAYKFENDFRTMADLELLKLDELDCLIHGLLYVDSVGFNGHPECYYFENPSDTHNCIKRPCCLDNPFPMLLVNIGSGVSILAVYSLGGGTFLGLC-----------CLLTGCETFEEALEMASKGDSTNADKLVRDIYGGDYQRFGLQGSAVASSFGHMMSKEKRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSRGQLRALFLEHEGYFGAVGAFLELLKSPEDP 347
BLAST of Pantothenate kinase 4 vs. Ensembl Cavefish
Match: pank2 (pantothenate kinase 2 [Source:NCBI gene;Acc:103044193]) HSP 1 Score: 140.584 bits (353), Expect = 2.076e-35 Identity = 121/353 (34.28%), Postives = 172/353 (48.73%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSD---------------------AERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIA---DEVFYFEEKSGP---NFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRH 1099
F MDIGG+LVK+VY K + E S K Y+ S + L FI+F T+ L P+F+ +D L TGGGA KF+ ++ + K DE++ L +G +++ +A E +Y+E + P + L NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+ +F+E L MAS G VD LV+DIYGG E LP +ASSF + D SKED + L+TI+NNIG ++ +C ++ + GF T G T + S++N S + A L H
Sbjct: 82 FGMDIGGTLVKLVYFEPKDITAEEEQEEVESLKSIRHYLTSHTAYGKTGIRDVHLELPDLILWGRKGSLHFIRFPTQEL-------------PAFLQMGRDKHFSSLHTTLCATGGGAYKFEADFRTMADLQLLKLDELDCLIKGVLYIDSVVARGPPECYYYENPTHPENCQQKAYNLENPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALEMASRGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMCKEKRDSVSKEDLARATLVTITNNIGSIT----RMCALNEVAEMGFHTEG---TKRKRKSALNGLSGPWLEAASLEH 414
BLAST of Pantothenate kinase 4 vs. Ensembl Sea Lamprey
Match: pank2 (pantothenate kinase 2 [Source:ZFIN;Acc:ZDB-GENE-070112-1952]) HSP 1 Score: 179.489 bits (454), Expect = 4.519e-50 Identity = 133/355 (37.46%), Postives = 194/355 (54.65%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSSICLMNPF------PFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
F +DIGG+LVK+VY K + E S K Y+ S + + + E L+ C LHFI + P+F+ +D L TGGGA KF+ + + K DE++ L +G ++ N E +YF S P C PF P LLVNIGSG+SIL V S ++ RV GTS+GGGTF G+ CL+ K+F+E L++A G+ NVD LV+DIYGG LP + +ASSF + + S+ED + L+TI+NNIG ++ + A +DR++F G F R + +MK+++ +++YWSK +++ALFL HEGY GA+GA L+
Sbjct: 14 FGLDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRHYLTSHVAYGQTGVRDVHLELHGLTMCGRTGSLHFIRFPTVDMPAFLAMGRDKHFSSLHTALCATGGGAYKFELDFRTMAELQLHKLDELDCLIQGVHYIDSVGFNGVAECYYF---SNPTQRERCQKTPFVLGDLYPLLLVNIGSGVSILAVHSPNNYKRVTGTSLGGGTFLGLSCLLTGCKTFEEALSLAERGDSTNVDKLVRDIYGGDYGRFGLPGSTVASSFGNMMCKERREAVSREDLARATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLEHEGYFGAVGALLE 365
BLAST of Pantothenate kinase 4 vs. Ensembl Sea Lamprey
Match: pank2 (pantothenate kinase 2 [Source:ZFIN;Acc:ZDB-GENE-070112-1952]) HSP 1 Score: 166.392 bits (420), Expect = 1.769e-45 Identity = 128/364 (35.16%), Postives = 197/364 (54.12%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVY---------------QTTKQFKRKVPVCEEVSYKYVD-SDAERNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFL--LKNIADEVFYFEEKSGPNFSSICLMNP------FPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
F +DIGG+LVK+VY ++ K +R + V+Y DA E + LS C +HFI P+F++ ++ + L TGGGA KF++ K +++ + K DE+E L +G +++ L E +Y+E+ P + C P +P LLVNIGSG+S+L V S + RV GTS+GGGTF G+ CL+ SFDE L++A G+ NVD LV+DIYGG E L + +ASSF + + SKED + L+TI+NNIG ++ + A ++R++F G F R + + ++++ ++ YWS +++A FL HEGY GA+GA L+
Sbjct: 15 FGLDIGGTLVKLVYFEPTDVSAEEEEAEVESLKSIRRYLT--SRVAYGTAGVRDAH--------LELRGLSLCGRTGTMHFIRFPTADVPAFLSMGREKGFSGLQTTLCATGGGAHKFEEDFLKMVHLQLHKLDELECLIQGLMYVESLGLERPECYYYEQ---PMEAEHCSKRPCTLGSRYPLLLVNIGSGVSMLAVYSPHDYRRVTGTSLGGGTFLGLCCLLTGCDSFDEALSLAERGDSTNVDKLVRDIYGGDYERFGLRGSAVASSFGQMISLDRREAVSKEDLAMATLVTITNNIGSIARMCALNEKMERVVFVGNFLRVNQLSRRLLAHAMEYWSGGQLKAFFLEHEGYFGAVGALLE 365
BLAST of Pantothenate kinase 4 vs. Ensembl Yeast
Match: CAB1 (Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase; catalyzes the first committed step in the universal biosynthetic pathway for synthesis of coenzyme A (CoA); transcriptionally regulated by Upc2p via a sterol response element [Source:SGD;Acc:S000002939]) HSP 1 Score: 192.586 bits (488), Expect = 6.690e-55 Identity = 139/366 (37.98%), Postives = 193/366 (52.73%), Query Frame = 2
Query: 152 NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLS---ECLHFIIENIVPPSFMNENKDYK-PHLKVTGGGATKFKDLLSKKLNVI--IDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNF--SSICLMNP---FPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSF--------------------------AFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKS 1138
N A+DIGG+L K+V+ S N L F ET+ + E LH II+ + N Y+ H+ TGGGA KF DLL + I I + +EME L G F + I DEVF + ++ G +S M+ +P+LLVNIGSG+SILKV +F+RVGG+S+GGGT WG+ LI +++D++L A G+ +VDMLV DIYG + L + IASSF + G F D SLL ISNNIGQ++ L A++ N+ I FGG +TRGH+ TM +S ++N+WS+ +A FL+HEGYLGA+GA+L +
Sbjct: 20 NLAIDIGGTLAKVVF----------------------SPIHSNRLMFYTIETEKIDKFMELLHSIIKE-------HNNGCYRMTHIIATGGGAFKFYDLLYENFPQIKGISRFEEMEGLIHGLDFFIHEIPDEVFTYNDQDGERIIPTSSGTMDSKAIYPYLLVNIGSGVSILKVTEPNNFSRVGGSSLGGGTLWGLLSLITGAQTYDQMLDWAQEGDNSSVDMLVGDIYGTDYNKIGLKSSAIASSFGKVFQNRMTSNKSLENNENKLYSSHESIEKNNGQMFKNPDICKSLLFAISNNIGQIAYLQAKINNIQNIYFGGSYTRGHLTTMNTLSYAINFWSQGSKQAFFLKHEGYLGAMGAFLSA 356
BLAST of Pantothenate kinase 4 vs. Ensembl Nematostella
Match: EDO27195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9X7]) HSP 1 Score: 257.299 bits (656), Expect = 2.406e-79 Identity = 132/281 (46.98%), Postives = 186/281 (66.19%), Query Frame = 2
Query: 1676 LLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWF--LKLSS-----KPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFA 2497
LLD + L ++ F DPY K++ENE A+K+F +I +L M+ RQ ++ G+LAGNVFDWG++E+ LM K+ ++ F A+++L+ RPWL D D W KL+S PP Y ++F DNSG D I+GV+PF E +SRG+ VIL+AN+ P++NDV E+VILI+ LA L P + SA+K+ +L+ + +G SPCLDLR + L + +LV++EGM R IHTN A FTCDS+K+AVIKN WLA RLGG ++SVVFK+E+ A
Sbjct: 1 LLDTREQCLNEFDFPDPYAELKQQENEEALKMFTRRIRELDKMESEQRQIALVRGMLAGNVFDWGAREVSDLMEKN---LLGFDTAMDRLEARPWLKDDLDEWISRTKLASVICLQGPP----YKLAVVFVDNSGVDIILGVMPFVRELVSRGTKVILAANSYPALNDVMHGELVILIERLAKLCPALKSAVKSGRLVAMASGVGSPCLDLRRIDADLAA--SCAEAELVLLEGMGRRIHTNFHARFTCDSIKLAVIKNRWLAERLGGNMYSVVFKFERVA 272
BLAST of Pantothenate kinase 4 vs. Ensembl Nematostella
Match: EDO37713 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEX1]) HSP 1 Score: 174.866 bits (442), Expect = 3.194e-48 Identity = 131/368 (35.60%), Postives = 195/368 (52.99%), Query Frame = 2
Query: 137 NLQVANFAMDIGGSLVKIVY-----------QTTKQFKRKVPVCEEVSY------------KYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYF----------EEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKP--GDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
N ++ F +DIGG+L+K+VY Q Q R+ + V Y K V + L FI+F T + L I + S +N + TGGGA KF+ + L V + K DE+E L G F+ + E +Y+ K F S +PFP+L+VNIGSG+SI+ V S + F R+ GTS+GGGTF G+ CL+ +F+E L+MA+ G+ VD LVKDIYGG NLP + +ASSF P + + ED S+ L+ I+NNIG ++ + A ++R++F G F R + MK+++ +++YWS+ ++ALFL+HEGY GA+GA L+
Sbjct: 3 NARLPCFGLDIGGTLLKLVYFEPYSSATCQEQVGLQALREF-IMSNVQYGADGTRDDVLEMKDVVIGGRKGNLHFIRFPTCQIGAFLE--IAKSLNASVLNSK------VCATGGGAFKFEHDFKEVLGVQLVKYDELECLIHGIHFINDHFHQECYYWTWGDQYSIAQATKVPYGFDS----DPFPYLVVNIGSGVSIMAVYSAEKFDRISGTSLGGGTFLGLCCLMTGCTTFEEALSMAARGDSTKVDKLVKDIYGGDYNKFNLPGDTVASSFGKMCYPERQNEVNNEDIASATLIMITNNIGSIARMCAVNAKIERVVFVGNFLRTNEIAMKLLAYAMDYWSQGTMKALFLQHEGYFGAVGALLE 357
BLAST of Pantothenate kinase 4 vs. Ensembl Medaka
Match: pank4 (pantothenate kinase 4 (inactive) [Source:NCBI gene;Acc:101161916]) HSP 1 Score: 605.134 bits (1559), Expect = 0.000e+0 Identity = 363/812 (44.70%), Postives = 487/812 (59.98%), Query Frame = 2
Query: 125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNP--FPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMK 2503
+ F NL+ A FA+DIGGSL K+ Y +T Q K V + S+ + +A + L FIKFE Y+ CL FI +++V N + K +K TGGGA KFK+L+ KKL + +DKEDEM L +GC F+LKNI E F + + F NP FP+LLVNIGSG+SI+KVESE F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG L L +LIASSF +A F KED SLL ISN+IGQL+CL+A+L + R+ FGGFF RGH TM I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK E N SW ENYAGS+ S + E+N + R G+ F++ E++R + +L LL P +Y PD+ DLT D AR+YWL CF+ + V SQ D + A R+ ++ + Y L L P +G LTVR LLD ++ L ++ F DPY K++EN+ A+K FQ + L+ + W RQF ++ G+LAGNVFDWG+K + ++ D F EA +L+ RPWL+DC+DRW +L P + L F DNSG D I+GV+PF E LSRG+ V+L++N+ P++NDVT E+ IL + +A++ P I S LK +L LV +G SPCLDL + + L ++ + DLV+IEGM RAIHTN A +C+SLK+AV+KN+WLA+RLGG+LFSVVFKYE A K
Sbjct: 22 QIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTAKEAPSDKLYEISMQEEVTARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAHKFKELIEKKLGLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYARHADSEFR-FQTTNPDIFPYLLVNIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGSYGCLGLTGDLIASSFGKSATADKDFCKEDMAKSLLHMISNDIGQLACLYAKLHGLSRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSPEMNPLQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLQDPSSYIPDTMDLTEDAPAREYWLYCFEEALDGVVKRAVASQPDPQEAA-ARAEKFCQKYRHKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKIKQRENDSALKYFQKAVKALEQLSWEDRQFALVRGVLAGNVFDWGAKAVSDVL--ESDPEFGFEEAKRQLEVRPWLVDCFDRWLERLKGPP-----HKCALFFVDNSGVDIILGVMPFVRELLSRGTEVVLASNSGPALNDVTNGELQILTERIAAMDPVIRSGLKEDRLTLVQSGSSSPCLDLSRLDKVLAMVVRERQTDLVIIEGMGRAIHTNYHAMLSCESLKMAVLKNSWLADRLGGKLFSVVFKYEVPAGK 768
BLAST of Pantothenate kinase 4 vs. Ensembl Medaka
Match: pank2 (pantothenate kinase 3 [Source:NCBI gene;Acc:101161204]) HSP 1 Score: 191.815 bits (486), Expect = 1.017e-53 Identity = 136/352 (38.64%), Postives = 202/352 (57.39%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLS-----ECLHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNI---ADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
F MDIGG+LVK+VY K + E + K Y+ S+ ++ + + E + L+ LHFI P+F+ +D L TGGGA KF+ + ++ + K DE++ L RG +++ + A E +YFE + P L NP+P LLVNIGSG+SIL V SE ++ RV GTS+GGGTF G+ CL+ +F+E L MAS G VD LV+DIYGG E LP +ASSF + + + SKED + L+TI+NNIG ++ + A +++R++F G F R + +MK+++ +++YWSK +++ALFLRHEGY GA+GA L+
Sbjct: 11 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRRYLTSNTAYGKSGIRDVHLELQELTLDGRTGNLHFIRFPTHDLPAFLQMGRDKHFSSLHTTLCATGGGAYKFESDFRRMADLELHKLDELDCLVRGVLYIDSVVSWGASECYYFENPTDPEQCVQKPYNLENPYPLLLVNIGSGVSILAVYSENNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALQMASEGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKRESVSKEDLARATLVTITNNIGSITRMCALNESIERVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLRHEGYFGAVGALLE 362
BLAST of Pantothenate kinase 4 vs. Ensembl Medaka
Match: pank2 (pantothenate kinase 3 [Source:NCBI gene;Acc:101161204]) HSP 1 Score: 192.971 bits (489), Expect = 1.400e-53 Identity = 136/352 (38.64%), Postives = 202/352 (57.39%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLS-----ECLHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNI---ADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
F MDIGG+LVK+VY K + E + K Y+ S+ ++ + + E + L+ LHFI P+F+ +D L TGGGA KF+ + ++ + K DE++ L RG +++ + A E +YFE + P L NP+P LLVNIGSG+SIL V SE ++ RV GTS+GGGTF G+ CL+ +F+E L MAS G VD LV+DIYGG E LP +ASSF + + + SKED + L+TI+NNIG ++ + A +++R++F G F R + +MK+++ +++YWSK +++ALFLRHEGY GA+GA L+
Sbjct: 71 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRRYLTSNTAYGKSGIRDVHLELQELTLDGRTGNLHFIRFPTHDLPAFLQMGRDKHFSSLHTTLCATGGGAYKFESDFRRMADLELHKLDELDCLVRGVLYIDSVVSWGASECYYFENPTDPEQCVQKPYNLENPYPLLLVNIGSGVSILAVYSENNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALQMASEGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKRESVSKEDLARATLVTITNNIGSITRMCALNESIERVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLRHEGYFGAVGALLE 422
BLAST of Pantothenate kinase 4 vs. Ensembl Medaka
Match: pank1a (pantothenate kinase 1 [Source:NCBI gene;Acc:101175261]) HSP 1 Score: 181.03 bits (458), Expect = 4.043e-49 Identity = 136/352 (38.64%), Postives = 203/352 (57.67%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVY----QTTKQFKRKVPVCEEVSYKYVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
F MDIGG+LVK+VY T + +++ + +Y+ S+ + + + E + L+ C LHFI P F+ +D L TGGGA KF++ ++ + K DE++ L RG +F+ + N E +YF+ S P S L NPFP LLVNIGSG+S+L V SE ++ RV GTS+GGGTF G+ CL+ ++F+E L MAS G+ NVD LVKDIYGG E L + +ASSF + D SKED + L+TI+NNIG ++ + A ++R++F G F R + + K+++ ++++WSK ++RALFL HEGY GA+GA ++
Sbjct: 93 FGMDIGGTLVKLVYFEPVDITAEEEQEEVENLKSIRRYLTSNVAYGKTGVRDVHLELRNLTMCGRTGNLHFIRFPTQAMPRFIQMGRDKNFSSLHTTLCATGGGAYKFENDFRAMADLELLKLDELDCLIRGLLFIDRIGFNGHPECYYFQNPSDPENCVKKSCNLDNPFPMLLVNIGSGVSVLAVYSEDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSKNVDKLVKDIYGGDYERFGLQGSAVASSFGHMMCKEKRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHEGYFGAVGALME 444
BLAST of Pantothenate kinase 4 vs. Ensembl Medaka
Match: pank1a (pantothenate kinase 1 [Source:NCBI gene;Acc:101175261]) HSP 1 Score: 166.392 bits (420), Expect = 4.218e-44 Identity = 130/341 (38.12%), Postives = 194/341 (56.89%), Query Frame = 2
Query: 155 FAMDIGGSLVKIVY----QTTKQFKRKVPVCEEVSYKYVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHE 1102
F MDIGG+LVK+VY T + +++ + +Y+ S+ + + + E + L+ C LHFI P F+ +D L TGGGA KF++ ++ + K DE++ L RG +F+ + N E +YF+ S P S L NPFP LLVNIGSG+S+L V SE ++ RV GTS+GGGTF G+ CL+ ++F+E L MAS G+ NVD LVKDIYGG E L + +ASSF + D SKED + L+TI+NNIG ++ + A ++R++F G F R + + K+++ ++++WSK ++RALFL HE
Sbjct: 93 FGMDIGGTLVKLVYFEPVDITAEEEQEEVENLKSIRRYLTSNVAYGKTGVRDVHLELRNLTMCGRTGNLHFIRFPTQAMPRFIQMGRDKNFSSLHTTLCATGGGAYKFENDFRAMADLELLKLDELDCLIRGLLFIDRIGFNGHPECYYFQNPSDPENCVKKSCNLDNPFPMLLVNIGSGVSVLAVYSEDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSKNVDKLVKDIYGGDYERFGLQGSAVASSFGHMMCKEKRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHE 433
BLAST of Pantothenate kinase 4 vs. Planmine SMEST
Match: SMESG000033316.1 (SMESG000033316.1) HSP 1 Score: 1667.51 bits (4317), Expect = 0.000e+0 Identity = 827/830 (99.64%), Postives = 829/830 (99.88%), Query Frame = 2
Query: 41 MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLSC 2530
MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVGGTSIGGGTFWGIGCLIAKGKSFDELL MASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAV+EELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFE+RELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLSC
Sbjct: 1 MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVGGTSIGGGTFWGIGCLIAKGKSFDELLAMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVVEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEIRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLSC 830
BLAST of Pantothenate kinase 4 vs. Planmine SMEST
Match: SMESG000045470.1 (SMESG000045470.1) HSP 1 Score: 176.022 bits (445), Expect = 4.588e-48 Identity = 132/397 (33.25%), Postives = 220/397 (55.42%), Query Frame = 2
Query: 23 INYSSQMYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVY---QTTKQFKRKVPVCEEVSYKYVDSDAERNCLCF----IKFETKYLSE---CLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK-NIADEVFYFEEKSGPNFSSICLM-------NPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
+N +S ++ K+ +P ++ +S +++ ++ F +DIGG+L K+VY Q T+ ++ V +K++ S+ F ++ + + L LHFI +EN + + KD + TGGGA KF L++ + + DE+ L G + ++ N E +Y+ S P+ ++ C+ NP+PFL+VNIGSG+SIL V + RV GTS+GGGTF G+ CL+ + +FDE + +A +G+ VD LV+DIYGG E L +L+ASSF + K D + ED + + L ++NNIG ++ L A++ NVDRI+F G F R + +M +++S++ +WS+ +++ALF+ HEGY GAIG+ L+
Sbjct: 2 LNSNSNGESSYPKSATPVTRIRRFSEKVN---------SIPFPWFGIDIGGTLTKLVYFEPQLTEVEEQTVKESVMHIHKFLISNVAYGNKGFRDVHLELKDQVLGGRKGSLHFIRFPTSEMENFILMAKDKNLKDAADTISATGGGAFKFAKDFENTLDMQLQRHDELFCLMCGLHYSMRTNPLSECYYY---SNPDNNTKCVKISYNLSNNPYPFLVVNIGSGVSILCVRGPNQYYRVSGTSLGGGTFLGLSCLLTECTTFDEAMKLAGNGDSNKVDKLVRDIYGGDYEQFGLSGHLVASSFGHMMSDKRRDLVTNEDLIKATLTMLTNNIGSIARLCAKIENVDRILFVGNFLRVNKISMLLLASAMEFWSEKQLKALFMEHEGYFGAIGSLLQ 386
BLAST of Pantothenate kinase 4 vs. Planmine SMEST
Match: SMESG000078194.1 (SMESG000078194.1) HSP 1 Score: 136.346 bits (342), Expect = 1.135e-37 Identity = 63/77 (81.82%), Postives = 69/77 (89.61%), Query Frame = 2
Query: 161 MDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKP 391
M I GS VK+VYQTTKQFKRKVPVCEEVSYKYV +DAE+NCLC KFET+YLSECLHF +ENI+PPSFMNENKDY P
Sbjct: 1 MGISGSFVKLVYQTTKQFKRKVPVCEEVSYKYVYNDAEQNCLCLFKFETEYLSECLHFSMENILPPSFMNENKDYIP 77
BLAST of Pantothenate kinase 4 vs. Planmine SMEST
Match: SMESG000063669.1 (SMESG000063669.1) HSP 1 Score: 63.5438 bits (153), Expect = 3.726e-12 Identity = 30/42 (71.43%), Postives = 34/42 (80.95%), Query Frame = 2
Query: 41 MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMD 166
MYFNFI+ VSPD LKHY NEIDLN LKETFSNLQ+ + +D
Sbjct: 1 MYFNFIQIVSPDEKLKHYHNEIDLNELKETFSNLQLFDSVLD 42
BLAST of Pantothenate kinase 4 vs. Planmine SMEST
Match: SMESG000008042.1 (SMESG000008042.1) HSP 1 Score: 52.7582 bits (125), Expect = 7.154e-7 Identity = 90/374 (24.06%), Postives = 148/374 (39.57%), Query Frame = 2
Query: 119 LKETFSNLQVANFAMDIGGSLVKIVY--QTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKE----DEMESLTRGCIFLLKNIADEVFYFE----EKSGP-----------NFSSICLMN-------PFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPEN---LIASSFAFAAKPGDHFSKEDAMSSL--LLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKS---KVRALFLRHEGYLGAIGAYL 1132
K+ F N ++D G SL K++Y ++ K + P + V L F+ L E L + EN ++ EN+ H VTG G K+ SK++ I++++ DE S RG F LK + E +E E P +F +I N FP + +GSG +++ S+ +F G F G+ I + +++E++ MA+ G+ NVD +DI + +P + A K F+K D SL L + I + C AE V + FG G++ +I +Y K + + G+ GA+GA +
Sbjct: 11 FKKCFLNQVEVLASLDRGCSLTKVIYFDKSDKNLADEDPSIDTV------------ILTLALFDNNNLDEVLLILKEN----AYFPENQTLPFH--VTGAGGDKY----SKRIKEILERDVIFIDEYLSQARGTYFFLKYASLEDIIYENVEIEDVEPIEAPFASNIKGHFDTIVTNNITEEDDEKFPCIFAIMGSGAGCMRLNSDGTFHMACNMIDVGKPFIGMCRCILETNNYEEIMDMAAKGDRRNVDTTTEDIVTADSPYGKIPGGISLIPLGKLADTNKDISEFNKNDIAHSLVSLFIYNAMINAIHCCIAE--KVKTVFFG-----GNLFQSEIFRKEYSYLRKVYTLDFVNFYFVNNGHSGALGAMV 355 The following BLAST results are available for this feature:
BLAST of Pantothenate kinase 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Pantothenate kinase 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Pantothenate kinase 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Pantothenate kinase 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Pantothenate kinase 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Pantothenate kinase 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030654 ID=SMED30030654|Name=Pantothenate kinase 4|organism=Schmidtea mediterranea sexual|type=transcript|length=2556bpback to top protein sequence of SMED30030654-orf-1 >SMED30030654-orf-1 ID=SMED30030654-orf-1|Name=SMED30030654-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=831bp MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIback to top Annotated Terms
The following terms have been associated with this transcript:
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