Pantothenate kinase 4

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER                 L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       + FP+LLVNIGSG+SI+KVE+E  F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA L ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER                 L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       + FP+LLVNIGSG+SI+KVE+E  F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA L ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER                 L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       + FP+LLVNIGSG+SI+KVE+E  F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA L ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   34 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 777          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER                 L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA                             F+ +  +D  F F+     N   I     FP+LLVNIGSG+SI+KVE+E  F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA L ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGA-----------------------------FVYQKDSDPEFRFQT----NHPHI-----FPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 730          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER                 L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA                             F+ +  +D  F F+     N   I     FP+LLVNIGSG+SI+KVE+E  F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA L ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGA-----------------------------FVYQKDSDPEFRFQT----NHPHI-----FPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 730          

Query:  146 VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFY--FEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFA--------AKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNV----PVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQ---SKILQLKSM-DWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQ 2491
            + +   D     VKIVY ++         C  +  K     +E    C I+ +       L+F  EN   P       D+     VT     + ++++ K L+V +   D    L  G  FLL+NI  E F   F+E     F ++   + FP+LL+NI +G+S++ VE E  F R+GG+SIGGG+F G+  LI      +E++  A  G+    D+ ++DIYG +    N+  +L+A+SF           A+  D  SK +A+ SLL  I  N+ QL+ + +E+ NV R+ F GF  R     MK +S + NYWS  K+RA FLRHE Y   +GA+L++F ++                 +  W E  +GS +      L + V  E   E  F  +T                      F +R    T  +   F LL   Q   PD+ D   D EAR +W++     +       I  Q      +    R+  ++ +++K +  + +    +G    R +L+  +  L++ GF D Y  +K  EN  A+       +KI +LK+  D  T    V  GLLAGNVFDWG+KE+V +M+ S+ G+  F  A++ ++ RPWL D +D ++ K          Y SVLIF DNSGFD+I+G++PFA E L  GS VI+ ANT P++ND+T+ E+V L   L +   ++   + + +++ V  GQ SPC+D R V + LN  ++    DLVVIEGM RA+HTN   +F CDSLK AVIK  WLA+RLGG++FSVVFK+E 
Sbjct:   20 ITHICFDACSKTVKIVYSSSVPLSHTTLECTRILSK----QSEDRIYC-IQVQYPDFPLILNFFGENC--PLLKGTTVDFV----VTASQNAEIEEVIRKVLDVELRHVDAFNGLVNGTSFLLRNIEAECFTYSFDESQEYEFQTLNNDSMFPYLLINIRTGVSVVLVEGENQFKRLGGSSIGGGSFLGLTELITGVSDIEEMMDRALQGSPDEFDIFIRDIYGDRASNFNMDPHLLAASFGRVTRGETVRRAENFDEQSKNNAILSLLRMILYNVSQLAYMLSEISNVKRVFFNGFLVRNRPIVMKTLSFACNYWSSGKLRAYFLRHENYTTGLGAFLENFPNA-----------------DLYWKEYCSGSTA------LGRFVPVE-PLETGFKTQT----------------------FALR---CTGFKAAPFALLVD-QDGKPDTIDFNKDEEARNFWIEILDKTINDITKFAIASQENCSNKEDLTNRAEDFQSDFVKTMDIIKEHHVAYGNSNARNMLEVREQILQEKGFDDIYVQKKHAENCTAIAELPRVLAKIDELKNTGDEKTVLEYVSRGLLAGNVFDWGAKEVVKMMN-SESGLT-FQTAIDHVENRPWLFDGFDSFYKKHKE-------YKSVLIFVDNSGFDYILGIIPFARELLRNGSRVIICANTSPALNDLTYREMVELAPELKNADSDLAKFIDSNQMMFVQTGQESPCMDARRVHQDLNETVKKFNTDLVVIEGMGRALHTNFNVQFKCDSLKAAVIKTQWLADRLGGKMFSVVFKHEH 749          

Query:  125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFG 1144
            +TF   +  +  ++DIGG+L+K+VY +    +         + KY   D +R  + F KF     ++   FI  N +   + +  +    H   TGGG+ K+ +++ K+L V + + DEM SL  G  FLL    DE F Y  +  G N   +  I     +PFLLVNIG+GISILKV+S  S+ RVGG+S+GGGTF G+G L+   ++FDELL MA+ G++ NVD LV DIYGG  + L L  +LIA S      F    K   H   ED   SLLL +SNNIGQ++ L+    N+ RI FGG+F R    TM+ +S ++NYWSK ++ AL+L+HEGYLGA+G++L   G
Sbjct:   59 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYFIRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFLDEDG 399          

Query:  125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFG 1144
            +TF   +  +  ++DIGG+L+K+VY +    +         + KY   D +R  + F KF     ++   FI  N +   + +  +    H   TGGG+ K+ +++ K+L V + + DEM SL  G  FLL    DE F Y  +  G N   +  I     +PFLLVNIG+GISILKV+S  S+ RVGG+S+GGGTF G+G L+   ++FDELL MA+ G++ NVD LV DIYGG  + L L  +LIA S      F    K   H   ED   SLLL +SNNIGQ++ L+    N+ RI FGG+F R    TM+ +S ++NYWSK ++ AL+L+HEGYLGA+G++L   G
Sbjct:   59 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYFIRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFLDEDG 399          

Query:  125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFG 1144
            +TF   +  +  ++DIGG+L+K+VY +    +         + KY   D +R  + F KF     ++   FI  N +   + +  +    H   TGGG+ K+ +++ K+L V + + DEM SL  G  FLL    DE F Y  +  G N   +  I     +PFLLVNIG+GISILKV+S  S+ RVGG+S+GGGTF G+G L+   ++FDELL MA+ G++ NVD LV DIYGG  + L L  +LIA S      F    K   H   ED   SLLL +SNNIGQ++ L+    N+ RI FGG+F R    TM+ +S ++NYWSK ++ AL+L+HEGYLGA+G++L   G
Sbjct:  105 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYFIRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFLDEDG 445          

Query:  125 ETFSNLQ-VANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVF-YFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASS------FAFAAKPGDHFSKEDAMSSLLLTISNNIGQL 952
            +TF   +  +  ++DIGG+L+K+VY +    +         + KY   D +R  + F KF     ++   FI  N +   + +  +    H   TGGG+ K+ +++ K+L V + + DEM SL  G  FLL    DE F Y  +  G N   +  I     +PFLLVNIG+GISILKV+S  S+ RVGG+S+GGGTF G+G L+   ++FDELL MA+ G++ NVD LV DIYGG  + L L  +LIA S      F    K   H   ED   SLLL +SNNIGQ+
Sbjct:  105 DTFEKFRKTSRVSVDIGGTLIKVVYSSVMDEELPEESLNGHTRKYAYEDGKRVLVNFKKF-----TDMDRFI--NFLKEVWTDRKRGDVIH--CTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDAIGRNKFQYRPIAADLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGGAYDELGLKADLIAGSMAKCNRFEETTKKQQH-KPEDIAKSLLLMVSNNIGQI 381          

Query: 1433 LLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLD-DIPTLHG--VLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSM-DWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGE-LFSVVFKYEQFA 2497
            LL  P  Y PD+ DL +D +A  YW  CF+  V     +  +SQ ++  TA  R+ Q++  YL+ L +   ++P   G  +L    LL  ++  LR+YGFTDP+  QK+ EN  A+   + ++ +L ++ D +TR  +++ G+LAGN+FDWG++ I  ++ +  D       A+++++ RPWL+D  D W  +L  +P     +   ++F DNSG D ++GV+PF    L RG+ V+L AN+EP++NDVT  E+  L+ + +     ++ A    +LL+  NGQ  PCLD+R + + L   I + + DL+VIEGM RA+HTNL A F C++LK+AVIKN WLA  LGGE +F+VV K+E  A
Sbjct:    6 LLPDPAVYQPDTLDLNTDGKAADYWFNCFRDMVAKFAKVAAKSQ-EEDHTATQRAEQFQAAYLQRLEEHQRNVPVNKGKVILGTSELLKLNETLLRRYGFTDPWLRQKRLENASAVARLKQRLQELDALADEDTRWTELVRGVLAGNMFDWGAQAISNILEQ--DSNFGLHSALDRIEKRPWLLDNLDSWLNRLKGEP-----HKCAVVFVDNSGVDVVLGVLPFVRGLLKRGTKVLLCANSEPALNDVTSEELKSLLDDCSRECEVLEQAWSKGQLLVYANGQTGPCLDMRTLPKELCDAIAANETDLLVIEGMGRALHTNLNARFGCETLKLAVIKNKWLAKYLGGEDMFAVVCKFEPAA 359          

Query: 1433 LLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLD-DIPTLHG--VLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSM-DWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGE-LFSVVFKYEQFA 2497
            LL  P  Y PD+ DL +D +A  YW  CF+  V     +  +SQ ++  TA  R+ Q++  YL+ L +   ++P   G  +L    LL  ++  LR+YGFTDP+  QK+ EN  A+   + ++ +L ++ D +TR  +++ G+LAGN+FDWG++ I  ++ +  D       A+++++ RPWL+D  D W  +L  +P     +   ++F DNSG D ++GV+PF    L RG+ V+L AN+EP++NDVT  E+  L+ + +     ++ A    +LL+  NGQ  PCLD+R + + L   I + + DL+VIEGM RA+HTNL A F C++LK+AVIKN WLA  LGGE +F+VV K+E  A
Sbjct:    6 LLPDPAVYQPDTLDLNTDGKAADYWFNCFRDMVAKFAKVAAKSQ-EEDHTATQRAEQFQAAYLQRLEEHQRNVPVNKGKVILGTSELLKLNETLLRRYGFTDPWLRQKRLENASAVARLKQRLQELDALADEDTRWTELVRGVLAGNMFDWGAQAISNILEQ--DSNFGLHSALDRIEKRPWLLDNLDSWLNRLKGEP-----HKCAVVFVDNSGVDVVLGVLPFVRGLLKRGTKVLLCANSEPALNDVTSEELKSLLDDCSRECEVLEQAWSKGQLLVYANGQTGPCLDMRTLPKELCDAIAANETDLLVIEGMGRALHTNLNARFGCETLKLAVIKNKWLAKYLGGEDMFAVVCKFEPAA 359          

Query:  155 FAMDIGGSLVKIVY-----QTTKQFKRKVPVCEEV------SYKYVDSDAERNCLCFIKFETKYLSECLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFE--------EKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQ 1180
            F MDIGG+L K+VY      T  +  R+  +   +      +  Y  +      L     E +     LHFI      + N +  +      +    +  TGGGA KF+     ++N+ + K DE+++L +G +F   +   E +Y+E        EK   NFS      PFPF+LVN+GSG+SIL V    ++ R+ GTS+GGGTF G+ CL+    SF+E + +A+ G+   VD LVKDIYGG      LP +L+ASSF            S+ED  ++ L+TI+NNIG ++ + A    +DR++F G F R +  +MK+++ ++ +WS   ++ LFL HEGY GA+G  L+  G+  + +N  +E 
Sbjct:    4 FGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGNFLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNFS-----QPFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQFNGELAAALNDGVEH 367          

Query:  155 FAMDIGGSLVKIVY-----QTTKQFKRKVPVCEEV------SYKYVDSDAERNCLCFIKFETKYLSECLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFE--------EKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQ 1180
            F MDIGG+L K+VY      T  +  R+  +   +      +  Y  +      L     E +     LHFI      + N +  +      +    +  TGGGA KF+     ++N+ + K DE+++L +G +F   +   E +Y+E        EK   NFS      PFPF+LVN+GSG+SIL V    ++ R+ GTS+GGGTF G+ CL+    SF+E + +A+ G+   VD LVKDIYGG      LP +L+ASSF            S+ED  ++ L+TI+NNIG ++ + A    +DR++F G F R +  +MK+++ ++ +WS   ++ LFL HEGY GA+G  L+  G+  + +N  +E 
Sbjct:    4 FGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGNFLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNFS-----QPFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQFNGELAAALNDGVEH 367          

Query:  155 FAMDIGGSLVKIVY-----QTTKQFKRKVPVCEEV------SYKYVDSDAERNCLCFIKFETKYLSECLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFE--------EKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQ 1180
            F MDIGG+L K+VY      T  +  R+  +   +      +  Y  +      L     E +     LHFI      + N +  +      +    +  TGGGA KF+     ++N+ + K DE+++L +G +F   +   E +Y+E        EK   NFS      PFPF+LVN+GSG+SIL V    ++ R+ GTS+GGGTF G+ CL+    SF+E + +A+ G+   VD LVKDIYGG      LP +L+ASSF            S+ED  ++ L+TI+NNIG ++ + A    +DR++F G F R +  +MK+++ ++ +WS   ++ LFL HEGY GA+G  L+  G+  + +N  +E 
Sbjct:   20 FGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGNFLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNFSQ-----PFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQFNGELAAALNDGVEH 383          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFK----RKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIP 1645
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    R      +VS++  D D              L FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL + +DKEDEM  L +GC F+LKNI  E F + + +   F       + FP+LL+NIGSG+SI+KVESE  F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG    L L  +LIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+L N+ R+ FGGFF RGH  TM  I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + ELN               + R G+                  F++ E++R + +L    LL+ P +Y PD+ DLT D  AR YWL CF+  +   V     SQKDQ + A+ R+ ++ + Y   L  L   P
Sbjct:   24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKVSFQETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDKEFSKEDMAKSLLHMISNDIGQLACLYAKLHNLTRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSPELNPVQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLHDPTSYIPDTVDLTEDALARDYWLYCFEDALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQP 495          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFK----RKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIP 1645
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    R      +VS++  D D              L FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL + +DKEDEM  L +GC F+LKNI  E F + + +   F       + FP+LL+NIGSG+SI+KVESE  F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG    L L  +LIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+L N+ R+ FGGFF RGH  TM  I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + ELN               + R G+                  F++ E++R + +L    LL+ P +Y PD+ DLT D  AR YWL CF+  +   V     SQKDQ + A+ R+ ++ + Y   L  L   P
Sbjct:   24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKVSFQETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDKEFSKEDMAKSLLHMISNDIGQLACLYAKLHNLTRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSPELNPVQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLHDPTSYIPDTVDLTEDALARDYWLYCFEDALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQP 495          

Query: 1208 SWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            SW ENYAGS+   S + ELN               + R G+                  F++ E++R + +L    LL+ P +Y PD+ DLT D  AR YWL CF+  +   V     SQKDQ + A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN+ A+K +   +  ++ + W  RQF ++ GLLAGNVFDWG+K +  ++    D    F +A  +LQ RPWL+D Y +W  ++   P     +   L F DNSG D I+GV PF  E L RG+ V+L++N+ P++NDVT SE+ IL + +A++ P I SA K  +L LV NG  SPCLDL  + + L  ++     DLV+IEGM RAIHTN  A  +C+SLK+AVIKN+WLA RLGG++FSVVFKYE
Sbjct:    6 SWGENYAGSSGLMSVSPELNPVQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLHDPTSYIPDTVDLTEDALARDYWLYCFEDALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKIKQKENDMALKYYLKVVKSVEELSWEQRQFALVKGLLAGNVFDWGAKAVSDVLET--DPEFGFEQAKQQLQERPWLVDAYSQWIERMKGPP-----HKCALFFVDNSGIDIILGVFPFIRELLLRGTEVVLASNSGPALNDVTNSELQILTERIAAMDPVIQSAFKEDRLALVQNGSSSPCLDLSRLDKVLATVVRERGTDLVIIEGMGRAIHTNYYAMLSCESLKLAVIKNSWLAERLGGKIFSVVFKYE 397          

Query:  170 GGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAE 970
            GGSL K+ Y +T Q K       + S K  D D              L FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL + +DKEDEM  L +GC F+LKNI  E F + + +   F       + FP+LL+NIGSG+SI+KVESE  F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG    L L  +LIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+
Sbjct:   30 GGSLTKLAYYSTVQHKVAKVRSFDHSAKETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDKEFSKEDMAKSLLHMISNDIGQLACLYAK 298          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAA 874
            E F NL+ A  FA+DIGGSL K+ Y +T Q K       + S K  D D              L FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL + +DKEDEM  L +GC F+LKNI  E F + + +   F       + FP+LL+NIGSG+SI+KVESE  F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG    L L  +LIASSF  +A
Sbjct:   24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTHPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSA 276          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDE--MESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNI-KTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCF----KGNVPVDIVYQSQ-KDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   DA+   L              FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL + +DKEDE  M  L +GC F+LKNI  E F + + + P F       N FP+LLVNIGSG+SI+KVE+E  F R+GG+SIGGGTFWG+G L+ K K FDELL +A+ G++ NVDMLVKDIYGG  +IL L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+  N+ ++ FGGFF RGH  TM  IS S+N++SK +V+ALFLRHEGYLG IGA+LK                E  N    SW ENYAGS+   +T              D + + +TR G+                  F++ E++R + +L    LL  P +Y PD+ DLT D  AR+YWL CF    +G     +  Q + KD +D AQ    ++++ Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN+ A+K FQ  I  L ++ W  +QF ++ GLLAGNVFDWG+K +  VL S S+ G   F EA  KLQ RPWL+D Y+ W  +L   P     +   LIF DNSG D I+G+ PF  E L+RG+ VIL+ N+ P++NDVT++E +I+ + +A++   I SAL++++L+LV  G  SPCLDL  + +GL  L++    DLV+IEGM RAIHTN  A F C+SLK+AVIKN+WLA RL G++FSVVFKYE
Sbjct:   28 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTGKDADHEQLYEISVQEEITARLHFIKFENAYIEICLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLGLKVDKEDEDEMTCLIKGCNFVLKNIPHEAFVYVKHADPEFRFQTTHPNIFPYLLVNIGSGVSIVKVEAEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNLIASSFGKSATIDKDFSKEDMAKSLLHMISNDIGQLACLYAKQHNLSQVYFGGFFIRGHPVTMHTISYSINFFSKGEVQALFLRHEGYLGTIGAFLKG--------------AEQDNPNMYSWGENYAGSSGLMSTS------------PDIYPMQRTRSGT------------------FDMLEMDRLERQLVNLPLLSDPSSYVPDTVDLTEDAMAREYWLSCFEEALEGVAKRAVASQPEAKDATDRAQ----KFQQKYFNKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKVKQKENDIALKYFQRVIKSLDALGWEEKQFALVKGLLAGNVFDWGAKAVSEVLESNSEFG---FEEAKEKLQARPWLVDTYNDWIARLRGSP-----HKCALIFVDNSGIDIILGIFPFVRELLARGTEVILACNSGPALNDVTYNESLIVTECIAAMDTTIQSALQDERLILVQTGSSSPCLDLSRLDKGLATLVKERNTDLVIIEGMGRAIHTNYYASFQCESLKLAVIKNSWLAERLQGKIFSVVFKYE 771          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNI-KTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCF----KGNVPVDIVYQSQ-KDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   DA+   L              FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL +  D EDEM  L +GC F+LKNI  E F + + + P F       N FP+LLVNIGSG+SI+KVE+E  F R+GG+SIGGGTFWG+G L+ K K FDELL +A+ G++ NVDMLVKDIYGG  +IL L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+  N+ ++ FGGFF RGH  TM  IS S+N++SK +V+ALFLRHEGYLG IGA+LK                E  N    SW ENYAGS+   +T              D + + +TR G+                  F++ E++R + +L    LL  P +Y PD+ DLT D  AR+YWL CF    +G     +  Q + KD +D AQ    ++++ Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN+ A+K FQ  I  L ++ W  +QF ++ GLLAGNVFDWG+K +  VL S S+ G   F EA  KLQ          ++     ++    P +   LIF DNSG D I+G+ PF  E L+RG+ VIL+ N+ P++NDVT++E +I+ + +A++   I SAL++++L+LV  G  SPCLDL  + +GL  L++    DLV+IEGM RAIHTN  A F C+SLK+AVIKN+WLA RL G++FSVVFKYE
Sbjct:   27 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTGKDADHEQLYEISVQEEITARLHFIKFENAYIEICLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLGLKYD-EDEMTCLIKGCNFVLKNIPHEAFVYVKHADPEFRFQTTHPNIFPYLLVNIGSGVSIVKVEAEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNLIASSFGKSATIDKDFSKEDMAKSLLHMISNDIGQLACLYAKQHNLSQVYFGGFFIRGHPVTMHTISYSINFFSKGEVQALFLRHEGYLGTIGAFLKG--------------AEQDNPNMYSWGENYAGSSGLMSTS------------PDIYPMQRTRSGT------------------FDMLEMDRLERQLVNLPLLSDPSSYVPDTVDLTEDAMAREYWLSCFEEALEGVAKRAVASQPEAKDATDRAQ----KFQQKYFNKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKVKQKENDIALKYFQRVIKSLDALGWEEKQFALVKGLLAGNVFDWGAKAVSEVLESNSEFG---FEEAKEKLQGEL-------KYSPHFETRKHGSP-HKCALIFVDNSGIDIILGIFPFVRELLARGTEVILACNSGPALNDVTYNESLIVTECIAAMDTTIQSALQDERLILVQTGSSSPCLDLSRLDKGLATLVKERNTDLVIIEGMGRAIHTNYYASFQCESLKLAVIKNSWLAERLQGKIFSVVFKYE 764          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNI-KTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFK----GNVPVDIVYQSQ-KDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   DA+   L              FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL +  D EDEM  L +GC F+LKNI  E F + + + P F       N FP+LLVNIGSG+SI+KVE+E  F R+GG+SIGGGTFWG+G L+ K K FDELL +A+ G++ NVDMLVKDIYGG  +IL L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+  N+ ++ FGGFF RGH  TM  IS S+N++SK +V+ALFLRHEGYLG IGA+LK                E  N    SW ENYAGS+   +T              D + + +TR G+                  F++ E++R + +L    LL  P +Y PD+ DLT D  AR+YWL CF+    G     +  Q + KD +D AQ    ++++ Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN+ A+K FQ  I  L ++ W  +QF ++ GLLAGNVF   ++   +++       I FS      Q  P                      +   LIF DNSG D I+G+ PF  E L+RG+ VIL+ N+ P++NDVT++E +I+ + +A++   I SAL++++L+LV  G  SPCLDL  + +GL  L++    DLV+IEGM RAIHTN  A F C+SLK+AVIKN+WLA RL G++FSVVFKYE
Sbjct:   24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTGKDADHEQLYEISVQEEITARLHFIKFENAYIEICLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLGLKYD-EDEMTCLIKGCNFVLKNIPHEAFVYVKHADPEFRFQTTHPNIFPYLLVNIGSGVSIVKVEAEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNLIASSFGKSATIDKDFSKEDMAKSLLHMISNDIGQLACLYAKQHNLSQVYFGGFFIRGHPVTMHTISYSINFFSKGEVQALFLRHEGYLGTIGAFLKG--------------AEQDNPNMYSWGENYAGSSGLMSTSP------------DIYPMQRTRSGT------------------FDMLEMDRLERQLVNLPLLSDPSSYVPDTVDLTEDAMAREYWLSCFEEALEGVAKRAVASQPEAKDATDRAQ----KFQQKYFNKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKVKQKENDIALKYFQRVIKSLDALGWEEKQFALVKGLLAGNVFYILNQPCYLIL-------ISFS----LFQGSP----------------------HKCALIFVDNSGIDIILGIFPFVRELLARGTEVILACNSGPALNDVTYNESLIVTECIAAMDTTIQSALQDERLILVQTGSSSPCLDLSRLDKGLATLVKERNTDLVIIEGMGRAIHTNYYASFQCESLKLAVIKNSWLAERLQGKIFSVVFKYE 738          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSF--MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSS---ICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHE 1102
            F MDIGG+LVK+VY   K    +    E  + K    Y+ S+    +  +  +  E K L+ C     LHFI         F  M   K++      L  TGGGA KF++      ++ + K DE++ L +G +++     N   E +YFE  +          CL NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+   ++F+E L MA+ G+  NVD LVKDIYGG  E  +L  + +ASSF    + +  D  SKED   + L+TI+NNIG ++ + A   N+DR+IF G F R ++ +MK++S +++YWSK +++ALFL HE
Sbjct:   10 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHRFIQMGSEKNFSSLHTTLCATGGGAYKFEEDFRTIADLQLHKLDELDCLIQGLLYVDSVGFNGRPECYYFENPTDTEQCQKKPYCLDNPYPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFSLQGSAVASSFGHMMSKEKRDSISKEDLARATLVTITNNIGSIARMCALNENIDRVIFVGNFLRINMVSMKLLSYAMDYWSKGQLKALFLEHE 350          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSF--MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSS---ICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHE 1102
            F MDIGG+LVK+VY   K    +    E  + K    Y+ S+    +  +  +  E K L+ C     LHFI         F  M   K++      L  TGGGA KF++      ++ + K DE++ L +G +++     N   E +YFE  +          CL NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+   ++F+E L MA+ G+  NVD LVKDIYGG  E  +L  + +ASSF    + +  D  SKED   + L+TI+NNIG ++ + A   N+DR+IF G F R ++ +MK++S +++YWSK +++ALFL HE
Sbjct:   14 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHRFIQMGSEKNFSSLHTTLCATGGGAYKFEEDFRTIADLQLHKLDELDCLIQGLLYVDSVGFNGRPECYYFENPTDTEQCQKKPYCLDNPYPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFSLQGSAVASSFGHMMSKEKRDSISKEDLARATLVTITNNIGSIARMCALNENIDRVIFVGNFLRINMVSMKLLSYAMDYWSKGQLKALFLEHE 354          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D E++                L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       N FP+LLVNIGSG+SI+KVE+E  F  +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+L  +DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYA S+   +T             E     + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  AR+YWL CF+  +   V     SQ +  D  + R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN  A+K FQS    L S+ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y +W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+  +LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RAIHTN  A   C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDVEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLES--DPQFGFEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSSPCLDLSRLDKGLAVLVRERGADLVVIEGMGRAIHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 769          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVS-----------------------------------------------RGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D E++                L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       N FP+LLVNIGSG+SI+KVE+E  F  +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+L  +DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYA S+   +T             E     + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  AR+YWL CF+  +   V     SQ +  D  + R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN  A+K FQS    L S+ W  RQ  ++ GLLAGNVFDWG+K +  VL S  + G   F EA  KLQ RPWL+D Y +W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+  +LLLV  G  SPCLDL   +                                               +GL  L+     DLVVIEGM RAIHTN  A   C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDVEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPQFG---FEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSSPCLDLSLCTSRTTTCMVLPFAMWVLWTKLKSLVEKCLSPLSILLACSVLSAKSRLDKGLAVLVRERGADLVVIEGMGRAIHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 816          

Query:  467 KEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKL 1996
            KED M  L +GC F+LKNI  E F +++ S P F       N FP+LLVNIGSG+SI+KVE+E  F  +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+L  +DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYA S+   +T             E     + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  AR+YWL CF+  +   V     SQ +  D  + R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN  A+K FQS    L S+ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y +W  +L
Sbjct:    2 KEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVL--ESDPQFGFEEAKRKLQERPWLVDSYTKWLQRL 468          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFIIENIVPPSF---MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSS---ICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSF 1141
            F MDIGG+LVK+VY   K    +    E  + K    Y+ S+    +  +  +  E K L+ C     LHFI            M   K++      L  TGGGA KF++      ++ + K DE++ L +G +++     N   E +YFE  + P        CL NP+P LLVN+GSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+   ++F+E L MA+ G+  NVD LVKDIYGG  E   L  + +ASSF    + +  +  SKED   + L+TI+NNIG ++ + A   N+DR++F G F R ++ +MK+++ ++++WSK +++ALFL HEGY GA+GA L+ F
Sbjct:   14 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELF 367          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFIIENIVPPSF---MNENKDYKP---HLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSF 1141
            F MDIGG+LVK+VY   K    +    E  + K    Y+ S+    +  +  +  E K L+ C     LHFI            M   K++      L  TGGGA KF++      ++ + K DE++ L +G +++     N   E +YFE  + P        CL NP+P LLVN+GSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+   ++F+E L MA+ G+  NVD LVKDIYGG  E   L  + +ASSF    + +  +  SKED   + L+TI+NNIG ++ + A   N+DR++F G F R ++ +MK+++ ++++WSK +++ALFL HEGY GA+GA L+ F
Sbjct:  189 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELF 542          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER+                L F+KFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       + FP+LLVNIGSG+SI+KVE+E  F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA L ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT  E +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTERDHEPPYEISVQEEITARLHFVKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSTSPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVNLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDTLGWEERQLALVKGLLAGNVFDWGAKAVSDVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHGESLIVAERIAGMDPVVHSALREERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALCCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER                 L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       + FP+LLVNIGSG+SI+KVE+E  F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA L ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSASPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVL--ESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   DAE++                L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       N FP+LLVNIGSG+SI+KVE+E  F  +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+L  +DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYA S+   +T             E     + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  AR+YWL CF+  +   V     SQ +  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN  A+K FQS    L S+ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y +W  +L   P     +   LIF DNSG D I+GV PF  E L RG  VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+  +LLLV  G   PCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDAEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTAP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESVDAAE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLES--DPQFGFEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLCRGIEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSPPCLDLSRLDKGLAVLVRERGADLVVIEGMGRAVHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 769          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D ER+                L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       + FP+LLVNIGSG+SI+KVE+   F  VGG+SIGGGTFWG+G L+ K K FDELL +AS G + NVD LV+D+YGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CLHA   ++DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + EL  A             + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  ARKYWL CF+  +   V     SQ D  D A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN  A++ F   +  L ++ W  RQ  ++ GLLAGNVFDWG+K +  ++    D    F EA  KLQ RPWL+D Y  W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT SE +I+ + +A + P + SAL+ ++LLLV  G  SPCLDL  + +GL  L+     DLVVIEGM RA+HTN  A   C+SLK+AVIKNAWLA RLGG LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHSGKDTERDHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETGDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDTLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARPHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAGSSGLMSTSPELGPAQ------------RARSGT------------------FDLLEMDRLERPLVNLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAE-RAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSDVL--ESDPCFGFEEAKRKLQERPWLVDSYSEWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALREERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYE 769          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC---------------LCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIV-VLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVS-----------------------------------------------RGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   D E++                L FIKFE  Y+  CL FI +++V       N + K  ++ TGGGA KFKDL+ +KL + +DKED M  L +GC F+LKNI  E F +++ S P F       N FP+LLVNIGSG+SI+KVE+E  F  +GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLV+DIYGG ++ L L  NLIASSF  +A     FSKED   SLL  ISN+IGQL+CL+A+L  +DR+ FGGFF RGH  TM+ I+ S+N++SK +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYA S+   +T             E     + R G+                  F++ E++R +  L    LL  P +Y PD+ DLT D  AR+YWL CF+  +   V     SQ +  D  + R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K+KEN  A+K FQS    L S+ W  RQ  ++ GLLAGNVFDWG+K +  VL S  + G   F EA  KLQ RPWL+D Y +W  +L   P     +   LIF DNSG D I+GV PF  E L RG+ VIL+ N+ P++NDVT+SE +I+ + +A++ P I +AL+  +LLLV  G  SPCLDL   +                                               +GL  L+     DLVVIEGM RAIHTN  A   C+SLK+AV+KNAWLA RLGG+LFSV+FKYE
Sbjct:   26 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHPGKDVEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLV-------NTETKV-IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKG--------------AEQDNPNQYSWGENYAASSGLMSTSP-----------ELCPTQRARSGT------------------FDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVE-RAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPQFG---FEEAKRKLQERPWLVDSYTKWLQRLKGPP-----HKCALIFADNSGIDIILGVFPFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSSPCLDLSLCTSRTTTCMVLPFAMWVLWTKLKSLVEKCLSPLSILLACSVLSAKSRLDKGLAVLVRERGADLVVIEGMGRAIHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYE 816          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVS-----------YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPP-----SFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSA----------------------------SFSNTKELNKAVIEELT-----FEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERT-------------------DDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVY--QSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKD---GIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKY 2485
            FA+DIGGSL K+ Y+ T ++KR VP   +             Y Y + + E   +C IKFET+ + ECL FI ENI+       + + + +  +P +KVTGGGA +FKDL+++ L V ++KEDEME L RGCIF+L+NI DE+F++++ + P   F S CL++ FPFLLVNIGSG+SILKVES  S++RVGGTSIGGGTFWGIG +++ GK SFD+LL +A  G++  VDMLV+DIYGG    + L  ++IASSF  AA+ P       DA+ SLL+T+SNNIGQL+CL+A+  N+ RI+FGGFF RGH  TM++I+ +VN+WS    RALFLRHEGYLGA+GA++K+           +++  + N   + W ENY  S                             S S   ELN+ +   ++     +ED+ ++      +   S+    + + A +  E+R   RT                   D  LE F  L SP TY PD+WDLT DTEAR YWL C K  V    +   +SQ D    A  RS QY + Y+ YL +L   P+  GVLTVRCLL A Q+FLR++GF D +  QKK EN  A+     ++  L ++ W+ RQF +  GLLAGNVFDWG+ E+V   +++     G+ +    + K+ PRPWLID YD+W   +S   P+   Y  VLIFCDNSG D ++GV+PFALE +SRGS VIL+AN+ P+INDVT+ E+ IL++ ++S    +  AL + +LL+  NGQ SPCLDLR  +  L +L++   VDLVVIEGM RAIHTNL A F  DSLK+AVIKNAWLA RLGG+L+ VVFK+
Sbjct:   39 FALDIGGSLAKLAYERTYRYKRSVPCPLDKPVPDNGLPPFTFYDYQEREHEGRKVCLIKFETRQIEECLEFIRENILQADAADATQLGDTETSRPAIKVTGGGAYRFKDLITRTLGVELNKEDEMECLIRGCIFMLRNIPDELFFYDKHATPAHVFVSDCLVDTFPFLLVNIGSGVSILKVESPTSYSRVGGTSIGGGTFWGIGSILSGGKCSFDQLLRLADQGDHRKVDMLVRDIYGGDYSAMGLQGDVIASSFGLAARSPEQPRCLADAVKSLLITVSNNIGQLACLYAKQHNLTRILFGGFFIRGHGLTMEVITYAVNFWSAGAYRALFLRHEGYLGAMGAFVKA-----------LDEWSSTNEPKTVWAENYVSSTRNACTMAEECILRSRQNSMASSQEFRGDSSSELTELNRGLSASMSAVPTEYEDTAHLSPGEPHLSMNSMQ--RVINSADLSSEIRLTSRTTVLKRPSLDTSYCELDRMMDFSLEPFPFLESPTTYVPDTWDLTQDTEARTYWLDCLKDGVERHRIKAEESQIDSMPDAAERSKQYADRYISYLQELGQNPSSCGVLTVRCLLSAQQHFLREFGFGDAFCRQKKLENRSALVSLPKRLNDLAALPWSERQFALASGLLAGNVFDWGAAEMVRFFAEAPTNSFGVPEMEATLAKIPPRPWLIDDYDKWIEAIS---PDRRPYRCVLIFCDNSGPDVLLGVLPFALEFISRGSKVILAANSAPAINDVTYQELDILLRLISSHVHVVAHALSSGRLLVAENGQTSPCLDLRLTASSLAHLVKREGVDLVVIEGMGRAIHTNLYARFRVDSLKVAVIKNAWLARRLGGQLYGVVFKF 876          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVS-----------YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPP-----SFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSA-----------------SFSNTKELNKAVIEELT----------------FED--SFNIKTRHGSIKS--KSLDDINISSKALIGFEVRELERT-------------DDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVY--QSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKD---GIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKY 2485
            FA+DIGGSL K+ Y+ T ++KR VP   +             Y Y + + E   +C IKFET+ + ECL FI ENI+       + + + +  +P +KVTGGGA +FKDL+++ L V ++KEDEME L RGCIF+L+NI DE+FY+++ + P   F S CL++ FPFLLVNIGSG+SILKVES  S++RVGGTSIGGGTFWGIG +++ GK SFD+LL +A  G++  VDMLV+DIYGG    + L  ++IASSF  AA+ P       DA+ SLL+T+SNNIGQL+CL+A+  N+ RI+FGGFF RGH  TM++I+ +VN+WS    RALFLRHEGYLGA+GA++K+           +++  + N   + W ENY  S                  S ++++E       ELT                +ED    +    H S+ S  + ++  ++SS+  +      L+R+             D  LE F  L SP TY PD+WDLT DTEAR YWL C K  V    +   +SQ D    A  RS QY + Y+ YL +L   P+  GVLTVRCLL A Q+FLR++GF D +  QKK EN  A+     ++  L ++ W+ RQF +  GLLAGNVFDWG+ E+V   +++     G+ +    + K+ PRPWLID YD+W   +S   P    Y  VLIFCDNSG D ++GV+PFALE +SRGS VIL+AN+ P+INDVT+ E+ IL++ ++S    +  AL + +LL+  NGQ SPCLDLR  +  L +L++   VDLVVIEGM RAIHTNL A F  DSLK+AVIKNAWLA RLGG+L+ VVFK+
Sbjct:   39 FALDIGGSLAKLAYERTYRYKRSVPCPLDKPVPDNGLPPFTFYDYQEREHEGRKVCLIKFETRQIEECLEFIRENILQADAADATQLGDTETSRPAIKVTGGGAYRFKDLITRTLGVELNKEDEMECLIRGCIFMLRNIPDELFYYDKHATPAHVFVSDCLVDTFPFLLVNIGSGVSILKVESPTSYSRVGGTSIGGGTFWGIGSILSGGKCSFDQLLRLADQGDHRKVDMLVRDIYGGDYSAMGLQGDVIASSFGLAARSPEQPRCLADAVKSLLITVSNNIGQLACLYAKQHNLTRILFGGFFIRGHGLTMEVITYAVNFWSAGAYRALFLRHEGYLGAMGAFVKA-----------LDEWSSTNEPKTVWAENYVSSTRNACTMAEECILRSRQNSMASSQEFRGDSSNELTELNRGLSASMSAVPTEYEDIARLSPGEPHLSMNSMQRVINSADLSSEIRLTSRTTVLKRSSLDTSYCELDRMMDFSLEPFPFLESPTTYVPDTWDLTQDTEARTYWLDCLKDGVERHRIKAEESQIDSMPDAAERSKQYADRYISYLQELGQNPSSCGVLTVRCLLSAQQHFLREFGFGDAFCRQKKLENRSALVSLPKRLNDLAALPWSERQFALASGLLAGNVFDWGAAEMVRFFAEAPTNSFGVPEMEATLAKIPPRPWLIDDYDKWIEAIS---PGRRPYRCVLIFCDNSGPDVLLGVLPFALEFISRGSKVILAANSAPAINDVTYQELDILLRLISSHVHVVAHALSSGRLLVAENGQTSPCLDLRLTASSLAHLVKREGVDLVVIEGMGRAIHTNLYARFRVDSLKVAVIKNAWLARRLGGQLYGVVFKF 876          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVP--VCEEVS--------YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENY---AGSASFSNTK---------------ELNKAVIEELTFEDSFNIKTR--HGSIKSKSLDDINISSKALIGFEVR---------ELERT-DDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDT---AQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMS---KSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLS-SKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            FA+DIGGSL K+VY+   +++R VP   C+ VS        Y+Y + + E   LCF+KFETK + ECL FI+ NI     +++    K  +KVTGGGA ++++L+  KL V +DKEDEM+ L RGC+F+L+NI DE+FY+++ + P   F   CL++ FPFLLVN+GSG+S LKVES  S+ RVGGTSIGGGTFWG+G L++ GK +FDELL MA  G++ +VDMLV+DIYGG  E L L  ++IASSF  AA+ P       D + SLL+T+SNNIGQL+CL+A+  ++ RIIFGG+F RGH  TM++I+ +V +WS  + +ALFLRHEGYLGA+GA+LK+  +     N+S E+        + W ENY   +G+  FS+                 + +K    +L   +S    +   H  I  K+ +  ++S ++      +         EL+R     LE+F LL SP  Y+PD+WDLT D EAR YWL CF+  +      ++++ QSDT   A  RS Q+ E Y ++L +L   P+ HGVLTVRCLL A Q+FLR+YGF D + +QK+ EN  A+     ++ +L  +DW+ RQ  +I GLLAGN+FDWG+ E +  +    K+K G  DF   ++K+Q RPWL+D YD W  ++S S  P    Y  +LIFCDNSG D I+GV+PFA+E LSRG  VI++AN+ P+IND+T+ E+ +L+  +AS  P I  +L N +L+L  NGQ SPCLD R ++  L  L E  +VDL+VIEGM RAIH NL ++FT D+LKIAVIKN+WLA RLGG+L+ V+FK+E
Sbjct:   26 FALDIGGSLAKLVYKRVFRYRRSVPQQCCKSVSENEIPFDFYEYTEHEDEGQKLCFMKFETKNIEECLDFILFNITHQGTLSKKTINK--IKVTGGGAYRYRELICSKLGVELDKEDEMDCLVRGCVFMLRNIPDELFYYDKHATPAHVFVPNCLVSTFPFLLVNVGSGVSFLKVESPTSYQRVGGTSIGGGTFWGLGTLLSGGKFTFDELLEMADSGDHRHVDMLVRDIYGGAYEALGLSGDVIASSFGLAARHPEQPRVLGDMVKSLLITVSNNIGQLACLYAKQHSLTRIIFGGYFIRGHGLTMEVITYAVRFWSGGEYKALFLRHEGYLGAVGAFLKACTN-----NNSTER-------KALWSENYVVSSGNTPFSDIPFESKLYATNHSKGEIDFSKVSSHDLPIVNSIGKVSNPNHSIIAQKAEESNSVSKRSSKSTSQKHEISKLPNFELDRVFTHSLEMFHLLESPANYSPDTWDLTHDEEARIYWLGCFESCIEYHRA-KAEESQSDTLSDASDRSHQFAERYKRFLRELSADPSGHGVLTVRCLLSAQQHFLREYGFGDVFCLQKRFENRAALSALTDRLSELSKLDWSNRQLSLIEGLLAGNMFDWGAAEAIQFLKEAPKNKFGAADFHAILDKVQSRPWLVDNYDNWINRISVSGSP----YRCILIFCDNSGADIILGVLPFAMEFLSRGCKVIMTANSSPAINDITYQELELLLHMIASFEPLIAESLNNGQLMLAENGQTSPCLDFRLLASSLVQLAEREQVDLIVIEGMGRAIHCNLNSKFTVDTLKIAVIKNSWLARRLGGQLYGVIFKFE 835          

Query:   62 TVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFK-------------RKVPVCEEVS-YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKD-YKPHLKVTGGGATKF-KDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGK-SFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSS-WIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDT----AQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKD---GIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLS 2527
            T +P   +  ++  ++    K     ++ A FA+DIGGSL K+ YQ T ++K             R+  VC     Y Y + + E + LCF+KFET+ +  CL FI   ++P S+ + ++D  +   +VTGGGA K+  ++L     V I++EDEM SL  GC FLL+NI DEVF +++++ P   F S C++N +PFLLVNIGSG+S LKVE++ S+ RVGGTS+GGGTFWGIG L+A G+ SFDELL +A  G++  VDMLVKDIYGG  E L LP ++IASSF  AA+ P +     D + +LL+ +SNNIGQL+CL+A    V RI+FGGFF RGH  TM++IS +VNYWS+ +++A+FLRHEGYLGA+GA++KS     +  +++ E  E      S  W E+YA             A+I               GSI + S    N    AL  FE+  L   D  LE F LL S   Y PD+WDLT D +AR YWL CFK  V   +  ++++ Q+++    ++ R+ Q+ E Y+++L++L D P+  G+LTVRC+L+A Q+ LR++GF D + +QK+ EN +A+  F S + +L  ++W  RQ  +  G+L GN+FDWG+ E V    +S+D   G+  F +A+ KLQPRPWL+D + RW  ++  +P + P  H VL+FCDNSG D I+GV+PF +ECL  GS VIL+AN+ P+INDVT+ E++ L+   A L P + +AL N KL+ V NGQ SPCLDLR  S  L +L++  KVDL+VIEGM RA+HTNL A F  D LK+AVIKN+WLA RLGG+LFSV+F+YE+++  ++L   LS
Sbjct:    5 TYAPPIDISSFAELVEEENQKHPHKIVECA-FALDIGGSLAKLAYQHTFRYKVCVPKELSDPDSKRRTSVCGPFEFYDYREHEYEGHKLCFVKFETRLIDSCLDFIRSTVLP-SYSDVDRDTIRLVGRVTGGGAFKYMSNILETLSGVEIEREDEMSSLVSGCTFLLRNIPDEVFIYDKRAMPAQIFLSSCMVNTYPFLLVNIGSGVSFLKVEADASYHRVGGTSLGGGTFWGIGSLLAGGQMSFDELLALADKGDHRQVDMLVKDIYGGAYESLGLPGDVIASSFGLAARRPNETRRPADMVKALLVAVSNNIGQLACLYAHQNGVRRILFGGFFIRGHRLTMEVISFAVNYWSQGEMKAMFLRHEGYLGAVGAFMKSRQQQETG-HTNGEAGEGVGKHTSKRWAESYA------------TALIS-------------RGSIPAFS----NAEGLALSEFELEHL--GDMSLEPFPLLLSSADYVPDTWDLTQDYKARVYWLGCFKQGVE-RLRRKAEESQAESDPHGSKQRARQFAERYVQFLSELSDRPSGRGILTVRCILEAQQHLLREFGFPDAFCVQKRAENSWALSCFPSIMERLGELNWEERQMALAQGVLTGNIFDWGASEAVRFFMQSQDSVEGMASFEKALAKLQPRPWLVDDFARWIERIR-RPDDRP--HCVLVFCDNSGADLILGVLPFVVECLDWGSKVILTANSVPAINDVTYRELLFLLNEAAGLEPRLQTALANGKLMCVDNGQSSPCLDLRQTSHNLVHLVKQEKVDLIVIEGMGRAVHTNLYARFCVDCLKVAVIKNSWLACRLGGDLFSVIFRYEEYS-NERLPMGLS 815          

Query:  248 YKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKL-NVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPN--FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIA-KGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAK-PGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKS-------FGDSTSPINSSIEQIEAYNIMNSSWIENYA---GSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIG---FEVRELERTDD----------------RLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDT---AQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSK---DGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFA 2497
            Y Y + + E + LCFIKFET+++  CL FI +NI+P      NK  K   +VTGGGA KF + ++ KL  + I++EDEMESL RGC FLL+NI DEVF +++++ P   F S C+++ +PFLLVNIGSG+S LKVES  +++RVGGTS+GGGTFWGIG L +  G SFDELL +A  GN++ VDMLV+DIYGG  E L L  + IASSF  AA+ P +     D + +LL+ +SNNIGQL+CL+A L NV RI+FGGFF RGH  TM++IS +V YWS+ K++A+FLRHEGYLGA+GA++K+        G STS   S +    ++++  S     Y     S+S    +  +   +    F  + N  +      + + DD + + K L     F +    RT D                 L  F LL SP  Y PD+WDLT DT+AR YWL+CF+      I  ++++ QSDT   A+ RS Q+ + Y  +L++L D P+  G+LTVRC+L+A Q+FLRK GF D +  QKK EN +A+  F   + +LK++DW+ RQ  +  G+LAGN+FDWG+ E V    +S+   DG+  F +  NK+ PRPWL+D +DRW  +++ +   E   H VLIFCDNSG D I+GV+PFA+ECL  G  VIL+AN++P+INDVT+ E++ L+  +A L   + +AL +++L+ V NGQ SPCLDLR VS+ L  L+   KVDL+V+EGM RA+HTNL A F  D LKIAVIKN+WLA  LGG LFSV+FKYE ++
Sbjct:   10 YDYREHEYEGHKLCFIKFETRFIEACLDFIRDNIMPDVV---NKHQKLVGRVTGGGAFKFLNTITTKLPGITIEREDEMESLVRGCAFLLRNIPDEVFTYDKRAEPAHIFLSSCMVDTYPFLLVNIGSGVSFLKVESGGTYSRVGGTSLGGGTFWGIGALFSGAGLSFDELLDLADQGNHLQVDMLVRDIYGGAYESLGLAGDTIASSFGLAARRPEEARRPADLIKALLIAVSNNIGQLACLYARLNNVQRILFGGFFIRGHALTMEVISFAVRYWSQGKMKAMFLRHEGYLGAVGAFMKNRMQGNSLAGSSTSWSESKVAGAPSFSVPGSGRRSIYPIQPHSSSSGQVRSPSDVFLSNTAFSGAAN--SLESETATDAPDDDSSTEKQLTPGPRFSLESNPRTLDFSTEWSAFELEHVVGVSLTTFPLLLSPADYVPDTWDLTQDTKARAYWLECFRQGAE-RIRQKAEESQSDTKSDAKARSQQFADLYFAFLSELADYPSGRGILTVRCILEAQQHFLRKLGFPDAFCHQKKLENSWALSFFPGMMERLKALDWSERQVALARGILAGNIFDWGASEAVRFFMQSQNSVDGMASFEQTQNKIPPRPWLMDDFDRWIQRIAVR---ERRPHCVLIFCDNSGADLILGVLPFAIECLDWGCKVILTANSDPAINDVTYPELLFLMNQVAELDERLTAALNSRRLICVDNGQNSPCLDLRRVSQNLVKLVNDEKVDLIVLEGMGRAVHTNLYARFCVDCLKIAVIKNSWLAGHLGGNLFSVIFKYEHYS 790          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFK-RKVPVCEEVSYKYV-DSDAE-----------RNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFS-SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIG-FEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYE 2488
            E F NL+ A  FA+DIGGSL K+ Y +T Q K  KV   +  +   V ++D E              L FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFKDL+ KKL + +DKEDEM  L +GC F+LKNI  E F + + +   F       + FP+LLVNIGSG+SI+KVESE  F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG    L L  +LIASSF  +A     FS+ED   SLL  ISN+IGQL+CL+A L N++R+ FGGFF RGH  TM  I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   +                                 D+N   +A  G F++ E++R + +L    LL  P +Y PD+ DLT D  AR+YWL CF+  +   V     SQKDQ + A+ R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN+ A+K +Q  +  L+ + W  RQF ++ G+LAGNVFDWG+K +  ++    D    F +A  +LQ RPWL+D Y++W  +L   P     +   L F DNSG D I+GV PF  E L RG+ V+L++N+ P++NDVT SE+ I+ + +A++ P I +A+K ++L+LV +G  SPCLDL  + + L  ++     DLV+IEGM RAIHTN  A  +C+SLK+AVIKN+WLA RLGG++FSVVFKYE
Sbjct:   24 EIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHTAKAGVQEADGEPLYEISVQEEITARLHFIKFENTYIETCLDFIKDHLV-------NTETKV-IKATGGGAYKFKDLIEKKLKLKVDKEDEMSCLIKGCNFVLKNIPHEAFVYAKHADSEFRFQNTRPDIFPYLLVNIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATADKEFSQEDMAKSLLHMISNDIGQLACLYARLHNLNRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSP------------------------------DLNPMQRARSGTFDMLEMDRLERQLVNLPLLQDPSSYIPDTVDLTEDALAREYWLYCFEEALDGVVKRAVASQKDQPEAAE-RAEKFRQKYRHKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKIKQRENDMALKYYQKVVRSLEELSWEQRQFALVRGILAGNVFDWGAKAVSDVL--ESDPEFGFEQAKQQLQERPWLVDAYNQWVERLKGPP-----HKCALFFVDNSGMDIILGVFPFVRELLLRGTEVVLASNSGPALNDVTNSELQIVTERIAAMDPVIQTAVKEERLILVQSGSSSPCLDLSRLDKVLATVVRERGTDLVIIEGMGRAIHTNYYAMLSCESLKLAVIKNSWLAERLGGKIFSVVFKYE 769          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNC------LCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            F MDIGG+LVK+VY   K    +    E  S K +      N       +  +  E K L+ C     LHFI        SF+   +D         L  TGGGA KF+D      N+ + K DE++ L +G +++     N   E ++F+  S P        CL NPFP LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+   ++F+E L MA+ G+  NVD LVKDIYGG  E   L  + +ASSF    + +  D  SKED   + L+TI+NNIG ++ + A    ++R++F G F R +  + K+++ ++++WSK +++ALFL HEGY GA+GA+L+
Sbjct:   92 FGMDIGGTLVKLVYFEPKDITAEEEQEEVESLKSIRRYLTSNVAYGDTGIRDVHLELKNLTMCGRTGNLHFIRFPTHDMHSFIQMGRDKNFSSLHTTLCATGGGAYKFEDDFRTVANLELQKLDELDCLIQGLLYVDSVGFNGHPECYFFQNPSDPENCVKQPCCLDNPFPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGHMMSKERRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLKALFLEHEGYFGAVGAFLE 443          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSD---------------------AERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIA---DEVFYFEEKSGP---NFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            F MDIGG+LVK+VY   K    +    E  S K    Y+ S                        +  L FI+F T+ L             P+F+   +D         L  TGGGA KF+       ++ + K DE++ L +G +++   +A    E +Y+E  + P      +  L NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+    +F+E L MAS G    VD LV+DIYGG  E   LP   +ASSF      +  D  SKED   + L+TI+NNIG ++ + A   N++R++F G F R +  +MK+++ +++YWSK +++ALFLRHEGY GA+GA L+
Sbjct:   82 FGMDIGGTLVKLVYFEPKDITAEEEQEEVESLKSIRHYLTSHTAYGKTGIRDVHLELPDLILWGRKGSLHFIRFPTQEL-------------PAFLQMGRDKHFSSLHTTLCATGGGAYKFEADFRTMADLQLLKLDELDCLIKGVLYIDSVVARGPPECYYYENPTHPENCQQKAYNLENPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALEMASRGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMCKEKRDSVSKEDLARATLVTITNNIGSITRMCALNENIERVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLRHEGYFGAVGALLE 433          

Query:  161 MDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFS---SICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSP 1159
            MDIGG+LVK+VY   K    +    E  + K    Y+ S+    +  +  +  E + L  C     LHFI         F+   +D         L  TGGGA KF++      ++ + K DE++ L  G +++     N   E +YFE  S  +       CL NPFP LLVNIGSG+SIL V S    T +G             CL+   ++F+E L MAS G+  N D LV+DIYGG  +   L  + +ASSF    + +  D  SKED   + L+TI+NNIG ++ + A    ++R++F G F R +  + K+++ ++++WS+ ++RALFL HEGY GA+GA+L+       P
Sbjct:    1 MDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRRYLTSNTAYGKTGVRDVHLELRNLRICGRTGTLHFIRFPTAAMHRFIQMGRDKNFSSLHTTLCATGGGAYKFENDFRTMADLELLKLDELDCLIHGLLYVDSVGFNGHPECYYFENPSDTHNCIKRPCCLDNPFPMLLVNIGSGVSILAVYSLGGGTFLGLC-----------CLLTGCETFEEALEMASKGDSTNADKLVRDIYGGDYQRFGLQGSAVASSFGHMMSKEKRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSRGQLRALFLEHEGYFGAVGAFLELLKSPEDP 347          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSD---------------------AERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIA---DEVFYFEEKSGP---NFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRH 1099
            F MDIGG+LVK+VY   K    +    E  S K    Y+ S                        +  L FI+F T+ L             P+F+   +D         L  TGGGA KF+       ++ + K DE++ L +G +++   +A    E +Y+E  + P      +  L NP+P LLVNIGSG+SIL V S+ ++ RV GTS+GGGTF G+ CL+    +F+E L MAS G    VD LV+DIYGG  E   LP   +ASSF      +  D  SKED   + L+TI+NNIG ++     +C ++ +   GF T G   T +   S++N  S   + A  L H
Sbjct:   82 FGMDIGGTLVKLVYFEPKDITAEEEQEEVESLKSIRHYLTSHTAYGKTGIRDVHLELPDLILWGRKGSLHFIRFPTQEL-------------PAFLQMGRDKHFSSLHTTLCATGGGAYKFEADFRTMADLQLLKLDELDCLIKGVLYIDSVVARGPPECYYYENPTHPENCQQKAYNLENPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALEMASRGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMCKEKRDSVSKEDLARATLVTITNNIGSIT----RMCALNEVAEMGFHTEG---TKRKRKSALNGLSGPWLEAASLEH 414          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPNFSSICLMNPF------PFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            F +DIGG+LVK+VY   K    +    E  S K    Y+ S     +  +  +  E   L+ C     LHFI    +  P+F+   +D         L  TGGGA KF+        + + K DE++ L +G  ++     N   E +YF   S P     C   PF      P LLVNIGSG+SIL V S  ++ RV GTS+GGGTF G+ CL+   K+F+E L++A  G+  NVD LV+DIYGG      LP + +ASSF      +  +  S+ED   + L+TI+NNIG ++ + A    +DR++F G F R +  +MK+++ +++YWSK +++ALFL HEGY GA+GA L+
Sbjct:   14 FGLDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRHYLTSHVAYGQTGVRDVHLELHGLTMCGRTGSLHFIRFPTVDMPAFLAMGRDKHFSSLHTALCATGGGAYKFELDFRTMAELQLHKLDELDCLIQGVHYIDSVGFNGVAECYYF---SNPTQRERCQKTPFVLGDLYPLLLVNIGSGVSILAVHSPNNYKRVTGTSLGGGTFLGLSCLLTGCKTFEEALSLAERGDSTNVDKLVRDIYGGDYGRFGLPGSTVASSFGNMMCKERREAVSREDLARATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLEHEGYFGAVGALLE 365          

Query:  155 FAMDIGGSLVKIVY---------------QTTKQFKRKVPVCEEVSYKYVD-SDAERNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFL--LKNIADEVFYFEEKSGPNFSSICLMNP------FPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            F +DIGG+LVK+VY               ++ K  +R +     V+Y      DA          E + LS C     +HFI       P+F++  ++      +  L  TGGGA KF++   K +++ + K DE+E L +G +++  L     E +Y+E+   P  +  C   P      +P LLVNIGSG+S+L V S   + RV GTS+GGGTF G+ CL+    SFDE L++A  G+  NVD LV+DIYGG  E   L  + +ASSF    +    +  SKED   + L+TI+NNIG ++ + A    ++R++F G F R +  + ++++ ++ YWS  +++A FL HEGY GA+GA L+
Sbjct:   15 FGLDIGGTLVKLVYFEPTDVSAEEEEAEVESLKSIRRYLT--SRVAYGTAGVRDAH--------LELRGLSLCGRTGTMHFIRFPTADVPAFLSMGREKGFSGLQTTLCATGGGAHKFEEDFLKMVHLQLHKLDELECLIQGLMYVESLGLERPECYYYEQ---PMEAEHCSKRPCTLGSRYPLLLVNIGSGVSMLAVYSPHDYRRVTGTSLGGGTFLGLCCLLTGCDSFDEALSLAERGDSTNVDKLVRDIYGGDYERFGLRGSAVASSFGQMISLDRREAVSKEDLAMATLVTITNNIGSIARMCALNEKMERVVFVGNFLRVNQLSRRLLAHAMEYWSGGQLKAFFLEHEGYFGAVGALLE 365          

Query:  152 NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLS---ECLHFIIENIVPPSFMNENKDYK-PHLKVTGGGATKFKDLLSKKLNVI--IDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNF--SSICLMNP---FPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSF--------------------------AFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKS 1138
            N A+DIGG+L K+V+                      S    N L F   ET+ +    E LH II+        + N  Y+  H+  TGGGA KF DLL +    I  I + +EME L  G  F +  I DEVF + ++ G     +S   M+    +P+LLVNIGSG+SILKV    +F+RVGG+S+GGGT WG+  LI   +++D++L  A  G+  +VDMLV DIYG     + L  + IASSF                          +     G  F   D   SLL  ISNNIGQ++ L A++ N+  I FGG +TRGH+ TM  +S ++N+WS+   +A FL+HEGYLGA+GA+L +
Sbjct:   20 NLAIDIGGTLAKVVF----------------------SPIHSNRLMFYTIETEKIDKFMELLHSIIKE-------HNNGCYRMTHIIATGGGAFKFYDLLYENFPQIKGISRFEEMEGLIHGLDFFIHEIPDEVFTYNDQDGERIIPTSSGTMDSKAIYPYLLVNIGSGVSILKVTEPNNFSRVGGSSLGGGTLWGLLSLITGAQTYDQMLDWAQEGDNSSVDMLVGDIYGTDYNKIGLKSSAIASSFGKVFQNRMTSNKSLENNENKLYSSHESIEKNNGQMFKNPDICKSLLFAISNNIGQIAYLQAKINNIQNIYFGGSYTRGHLTTMNTLSYAINFWSQGSKQAFFLKHEGYLGAMGAFLSA 356          

Query: 1676 LLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWF--LKLSS-----KPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFA 2497
            LLD  +  L ++ F DPY   K++ENE A+K+F  +I +L  M+   RQ  ++ G+LAGNVFDWG++E+  LM K+   ++ F  A+++L+ RPWL D  D W    KL+S      PP    Y   ++F DNSG D I+GV+PF  E +SRG+ VIL+AN+ P++NDV   E+VILI+ LA L P + SA+K+ +L+ + +G  SPCLDLR +   L       + +LV++EGM R IHTN  A FTCDS+K+AVIKN WLA RLGG ++SVVFK+E+ A
Sbjct:    1 LLDTREQCLNEFDFPDPYAELKQQENEEALKMFTRRIRELDKMESEQRQIALVRGMLAGNVFDWGAREVSDLMEKN---LLGFDTAMDRLEARPWLKDDLDEWISRTKLASVICLQGPP----YKLAVVFVDNSGVDIILGVMPFVRELVSRGTKVILAANSYPALNDVMHGELVILIERLAKLCPALKSAVKSGRLVAMASGVGSPCLDLRRIDADLAA--SCAEAELVLLEGMGRRIHTNFHARFTCDSIKLAVIKNRWLAERLGGNMYSVVFKFERVA 272          

Query:  137 NLQVANFAMDIGGSLVKIVY-----------QTTKQFKRKVPVCEEVSY------------KYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYF----------EEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKP--GDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            N ++  F +DIGG+L+K+VY           Q   Q  R+  +   V Y            K V     +  L FI+F T  +   L   I   +  S +N        +  TGGGA KF+    + L V + K DE+E L  G  F+  +   E +Y+            K    F S    +PFP+L+VNIGSG+SI+ V S + F R+ GTS+GGGTF G+ CL+    +F+E L+MA+ G+   VD LVKDIYGG     NLP + +ASSF     P   +  + ED  S+ L+ I+NNIG ++ + A    ++R++F G F R +   MK+++ +++YWS+  ++ALFL+HEGY GA+GA L+
Sbjct:    3 NARLPCFGLDIGGTLLKLVYFEPYSSATCQEQVGLQALREF-IMSNVQYGADGTRDDVLEMKDVVIGGRKGNLHFIRFPTCQIGAFLE--IAKSLNASVLNSK------VCATGGGAFKFEHDFKEVLGVQLVKYDELECLIHGIHFINDHFHQECYYWTWGDQYSIAQATKVPYGFDS----DPFPYLVVNIGSGVSIMAVYSAEKFDRISGTSLGGGTFLGLCCLMTGCTTFEEALSMAARGDSTKVDKLVKDIYGGDYNKFNLPGDTVASSFGKMCYPERQNEVNNEDIASATLIMITNNIGSIARMCAVNAKIERVVFVGNFLRTNEIAMKLLAYAMDYWSQGTMKALFLQHEGYFGAVGALLE 357          

Query:  125 ETFSNLQVA-NFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLC-------------FIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNP--FPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASF-SNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVP--VDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMK 2503
            + F NL+ A  FA+DIGGSL K+ Y +T Q K    V +  S+ +   +A  + L              FIKFE  Y+  CL FI +++V       N + K  +K TGGGA KFK+L+ KKL + +DKEDEM  L +GC F+LKNI  E F +   +   F      NP  FP+LLVNIGSG+SI+KVESE  F R+GG+SIGGGTFWG+G L+ K K FDELL +AS G + NVDMLVKDIYGG    L L  +LIASSF  +A     F KED   SLL  ISN+IGQL+CL+A+L  + R+ FGGFF RGH  TM  I+ S+N+++K +V+ALFLRHEGYLGAIGA+LK                E  N    SW ENYAGS+   S + E+N               + R G+                  F++ E++R + +L    LL  P +Y PD+ DLT D  AR+YWL CF+  +   V     SQ D  + A  R+ ++ + Y   L  L   P  +G LTVR LLD  ++ L ++ F DPY   K++EN+ A+K FQ  +  L+ + W  RQF ++ G+LAGNVFDWG+K +  ++    D    F EA  +L+ RPWL+DC+DRW  +L   P     +   L F DNSG D I+GV+PF  E LSRG+ V+L++N+ P++NDVT  E+ IL + +A++ P I S LK  +L LV +G  SPCLDL  + + L  ++   + DLV+IEGM RAIHTN  A  +C+SLK+AV+KN+WLA+RLGG+LFSVVFKYE  A K
Sbjct:   22 QIFRNLENAKRFAIDIGGSLTKLAYYSTVQHK----VAKVRSFDHTAKEAPSDKLYEISMQEEVTARLHFIKFENAYIETCLDFIKDHLV-------NTETKV-IKATGGGAHKFKELIEKKLGLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYARHADSEFR-FQTTNPDIFPYLLVNIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGSYGCLGLTGDLIASSFGKSATADKDFCKEDMAKSLLHMISNDIGQLACLYAKLHGLSRVYFGGFFIRGHPVTMHTITYSINFFTKGEVQALFLRHEGYLGAIGAFLKG--------------AEEDNPNQYSWGENYAGSSGLMSVSPEMNPLQ------------RARSGT------------------FDMLEMDRLERQLVNLPLLQDPSSYIPDTMDLTEDAPAREYWLYCFEEALDGVVKRAVASQPDPQEAA-ARAEKFCQKYRHKLQTLRHQPFAYGSLTVRSLLDTREHCLNEFNFPDPYSKIKQRENDSALKYFQKAVKALEQLSWEDRQFALVRGVLAGNVFDWGAKAVSDVL--ESDPEFGFEEAKRQLEVRPWLVDCFDRWLERLKGPP-----HKCALFFVDNSGVDIILGVMPFVRELLSRGTEVVLASNSGPALNDVTNGELQILTERIAAMDPVIRSGLKEDRLTLVQSGSSSPCLDLSRLDKVLAMVVRERQTDLVIIEGMGRAIHTNYHAMLSCESLKMAVLKNSWLADRLGGKLFSVVFKYEVPAGK 768          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLS-----ECLHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNI---ADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            F MDIGG+LVK+VY   K    +    E  + K    Y+ S+    ++ +  +  E + L+       LHFI       P+F+   +D         L  TGGGA KF+    +  ++ + K DE++ L RG +++   +   A E +YFE  + P         L NP+P LLVNIGSG+SIL V SE ++ RV GTS+GGGTF G+ CL+    +F+E L MAS G    VD LV+DIYGG  E   LP   +ASSF    + +  +  SKED   + L+TI+NNIG ++ + A   +++R++F G F R +  +MK+++ +++YWSK +++ALFLRHEGY GA+GA L+
Sbjct:   11 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRRYLTSNTAYGKSGIRDVHLELQELTLDGRTGNLHFIRFPTHDLPAFLQMGRDKHFSSLHTTLCATGGGAYKFESDFRRMADLELHKLDELDCLVRGVLYIDSVVSWGASECYYFENPTDPEQCVQKPYNLENPYPLLLVNIGSGVSILAVYSENNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALQMASEGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKRESVSKEDLARATLVTITNNIGSITRMCALNESIERVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLRHEGYFGAVGALLE 362          

Query:  155 FAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYK----YVDSDAE--RNCLCFIKFETKYLS-----ECLHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNI---ADEVFYFEEKSGPNF---SSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            F MDIGG+LVK+VY   K    +    E  + K    Y+ S+    ++ +  +  E + L+       LHFI       P+F+   +D         L  TGGGA KF+    +  ++ + K DE++ L RG +++   +   A E +YFE  + P         L NP+P LLVNIGSG+SIL V SE ++ RV GTS+GGGTF G+ CL+    +F+E L MAS G    VD LV+DIYGG  E   LP   +ASSF    + +  +  SKED   + L+TI+NNIG ++ + A   +++R++F G F R +  +MK+++ +++YWSK +++ALFLRHEGY GA+GA L+
Sbjct:   71 FGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRRYLTSNTAYGKSGIRDVHLELQELTLDGRTGNLHFIRFPTHDLPAFLQMGRDKHFSSLHTTLCATGGGAYKFESDFRRMADLELHKLDELDCLVRGVLYIDSVVSWGASECYYFENPTDPEQCVQKPYNLENPYPLLLVNIGSGVSILAVYSENNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALQMASEGESTRVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKRESVSKEDLARATLVTITNNIGSITRMCALNESIERVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLRHEGYFGAVGALLE 422          

Query:  155 FAMDIGGSLVKIVY----QTTKQFKRKVPVCEEVSYKYVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            F MDIGG+LVK+VY      T + +++     +   +Y+ S+    +  +  +  E + L+ C     LHFI       P F+   +D         L  TGGGA KF++      ++ + K DE++ L RG +F+ +   N   E +YF+  S P      S  L NPFP LLVNIGSG+S+L V SE ++ RV GTS+GGGTF G+ CL+   ++F+E L MAS G+  NVD LVKDIYGG  E   L  + +ASSF      +  D  SKED   + L+TI+NNIG ++ + A    ++R++F G F R +  + K+++ ++++WSK ++RALFL HEGY GA+GA ++
Sbjct:   93 FGMDIGGTLVKLVYFEPVDITAEEEQEEVENLKSIRRYLTSNVAYGKTGVRDVHLELRNLTMCGRTGNLHFIRFPTQAMPRFIQMGRDKNFSSLHTTLCATGGGAYKFENDFRAMADLELLKLDELDCLIRGLLFIDRIGFNGHPECYYFQNPSDPENCVKKSCNLDNPFPMLLVNIGSGVSVLAVYSEDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSKNVDKLVKDIYGGDYERFGLQGSAVASSFGHMMCKEKRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHEGYFGAVGALME 444          

Query:  155 FAMDIGGSLVKIVY----QTTKQFKRKVPVCEEVSYKYVDSDAE--RNCLCFIKFETKYLSEC-----LHFI-IENIVPPSFMNENKD-----YKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK---NIADEVFYFEEKSGPN---FSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHE 1102
            F MDIGG+LVK+VY      T + +++     +   +Y+ S+    +  +  +  E + L+ C     LHFI       P F+   +D         L  TGGGA KF++      ++ + K DE++ L RG +F+ +   N   E +YF+  S P      S  L NPFP LLVNIGSG+S+L V SE ++ RV GTS+GGGTF G+ CL+   ++F+E L MAS G+  NVD LVKDIYGG  E   L  + +ASSF      +  D  SKED   + L+TI+NNIG ++ + A    ++R++F G F R +  + K+++ ++++WSK ++RALFL HE
Sbjct:   93 FGMDIGGTLVKLVYFEPVDITAEEEQEEVENLKSIRRYLTSNVAYGKTGVRDVHLELRNLTMCGRTGNLHFIRFPTQAMPRFIQMGRDKNFSSLHTTLCATGGGAYKFENDFRAMADLELLKLDELDCLIRGLLFIDRIGFNGHPECYYFQNPSDPENCVKKSCNLDNPFPMLLVNIGSGVSVLAVYSEDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSKNVDKLVKDIYGGDYERFGLQGSAVASSFGHMMCKEKRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHE 433          

Query:   41 MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVIEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEVRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLSC 2530
            MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVGGTSIGGGTFWGIGCLIAKGKSFDELL MASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAV+EELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFE+RELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLSC
Sbjct:    1 MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLKNIADEVFYFEEKSGPNFSSICLMNPFPFLLVNIGSGISILKVESEQSFTRVGGTSIGGGTFWGIGCLIAKGKSFDELLAMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFAFAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLKSFGDSTSPINSSIEQIEAYNIMNSSWIENYAGSASFSNTKELNKAVVEELTFEDSFNIKTRHGSIKSKSLDDINISSKALIGFEIRELERTDDRLEVFKLLYSPQTYNPDSWDLTSDTEARKYWLKCFKGNVPVDIVYQSQKDQSDTAQTRSVQYEENYLKYLTDLDDIPTLHGVLTVRCLLDAHQNFLRKYGFTDPYWIQKKKENEFAMKLFQSKILQLKSMDWNTRQFQVILGLLAGNVFDWGSKEIVVLMSKSKDGIIDFSEAVNKLQPRPWLIDCYDRWFLKLSSKPPNEPIYHSVLIFCDNSGFDFIIGVVPFALECLSRGSTVILSANTEPSINDVTFSEIVILIKNLASLSPEIDSALKNKKLLLVPNGQISPCLDLRFVSRGLNYLIESLKVDLVVIEGMARAIHTNLLAEFTCDSLKIAVIKNAWLANRLGGELFSVVFKYEQFAMKDKLMFSLSC 830          

Query:   23 INYSSQMYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMDIGGSLVKIVY---QTTKQFKRKVPVCEEVSYKYVDSDAERNCLCF----IKFETKYLSE---CLHFI------IENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKEDEMESLTRGCIFLLK-NIADEVFYFEEKSGPNFSSICLM-------NPFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPENLIASSFA--FAAKPGDHFSKEDAMSSLLLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKSKVRALFLRHEGYLGAIGAYLK 1135
            +N +S    ++ K+ +P   ++ +S +++         ++    F +DIGG+L K+VY   Q T+  ++ V       +K++ S+       F    ++ + + L      LHFI      +EN +  +     KD    +  TGGGA KF       L++ + + DE+  L  G  + ++ N   E +Y+   S P+ ++ C+        NP+PFL+VNIGSG+SIL V     + RV GTS+GGGTF G+ CL+ +  +FDE + +A +G+   VD LV+DIYGG  E   L  +L+ASSF    + K  D  + ED + + L  ++NNIG ++ L A++ NVDRI+F G F R +  +M +++S++ +WS+ +++ALF+ HEGY GAIG+ L+
Sbjct:    2 LNSNSNGESSYPKSATPVTRIRRFSEKVN---------SIPFPWFGIDIGGTLTKLVYFEPQLTEVEEQTVKESVMHIHKFLISNVAYGNKGFRDVHLELKDQVLGGRKGSLHFIRFPTSEMENFILMAKDKNLKDAADTISATGGGAFKFAKDFENTLDMQLQRHDELFCLMCGLHYSMRTNPLSECYYY---SNPDNNTKCVKISYNLSNNPYPFLVVNIGSGVSILCVRGPNQYYRVSGTSLGGGTFLGLSCLLTECTTFDEAMKLAGNGDSNKVDKLVRDIYGGDYEQFGLSGHLVASSFGHMMSDKRRDLVTNEDLIKATLTMLTNNIGSIARLCAKIENVDRILFVGNFLRVNKISMLLLASAMEFWSEKQLKALFMEHEGYFGAIGSLLQ 386          

Query:  161 MDIGGSLVKIVYQTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKP 391
            M I GS VK+VYQTTKQFKRKVPVCEEVSYKYV +DAE+NCLC  KFET+YLSECLHF +ENI+PPSFMNENKDY P
Sbjct:    1 MGISGSFVKLVYQTTKQFKRKVPVCEEVSYKYVYNDAEQNCLCLFKFETEYLSECLHFSMENILPPSFMNENKDYIP 77          

Query:   41 MYFNFIKTVSPDATLKHYSNEIDLNVLKETFSNLQVANFAMD 166
            MYFNFI+ VSPD  LKHY NEIDLN LKETFSNLQ+ +  +D
Sbjct:    1 MYFNFIQIVSPDEKLKHYHNEIDLNELKETFSNLQLFDSVLD 42          

Query:  119 LKETFSNLQVANFAMDIGGSLVKIVY--QTTKQFKRKVPVCEEVSYKYVDSDAERNCLCFIKFETKYLSECLHFIIENIVPPSFMNENKDYKPHLKVTGGGATKFKDLLSKKLNVIIDKE----DEMESLTRGCIFLLKNIADEVFYFE----EKSGP-----------NFSSICLMN-------PFPFLLVNIGSGISILKVESEQSFTRVXXXXXXXXXXXXXXCLIAKGKSFDELLTMASHGNYMNVDMLVKDIYGGQNEILNLPEN---LIASSFAFAAKPGDHFSKEDAMSSL--LLTISNNIGQLSCLHAELCNVDRIIFGGFFTRGHIQTMKIISSSVNYWSKS---KVRALFLRHEGYLGAIGAYL 1132
             K+ F N      ++D G SL K++Y  ++ K    + P  + V             L    F+   L E L  + EN    ++  EN+    H  VTG G  K+    SK++  I++++    DE  S  RG  F LK  + E   +E    E   P           +F +I   N        FP +   +GSG   +++ S+ +F         G  F G+   I +  +++E++ MA+ G+  NVD   +DI    +    +P     +     A   K    F+K D   SL  L   +  I  + C  AE   V  + FG     G++   +I     +Y  K         +  + G+ GA+GA +
Sbjct:   11 FKKCFLNQVEVLASLDRGCSLTKVIYFDKSDKNLADEDPSIDTV------------ILTLALFDNNNLDEVLLILKEN----AYFPENQTLPFH--VTGAGGDKY----SKRIKEILERDVIFIDEYLSQARGTYFFLKYASLEDIIYENVEIEDVEPIEAPFASNIKGHFDTIVTNNITEEDDEKFPCIFAIMGSGAGCMRLNSDGTFHMACNMIDVGKPFIGMCRCILETNNYEEIMDMAAKGDRRNVDTTTEDIVTADSPYGKIPGGISLIPLGKLADTNKDISEFNKNDIAHSLVSLFIYNAMINAIHCCIAE--KVKTVFFG-----GNLFQSEIFRKEYSYLRKVYTLDFVNFYFVNNGHSGALGAMV 355