Calcium activated potassium channel subunit

Overview


Name	Calcium activated potassium channel subunit
Smed ID	SMED30030583
Length (bp)	860

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Calcium activated potassium channel subunit (SMED30030583) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcium activated potassium channel subunit (SMED30030583) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcium activated potassium channel subunit (SMED30030583) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030583

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30030583	SMESG000047387.1	dd_Smed_v4_15809_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30030583	SMESG000047387.1	dd_Smed_v4_15809_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30030583	SMESG000047387.1	dd_Smed_v6_15809_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Human
Match: KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6286])

HSP 1 Score: 56.9954 bits (136), Expect = 4.518e-9
Identity = 36/127 (28.35%), Postives = 63/127 (49.61%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
            S CTL+N +IT +  C   C  D    S +PCLQ+    T   ++ L Y  +    ++     +C+  P C  + +++  +V+      RK   F+CY + E ++  V+L K YS  + +H + WP+
Sbjct:   63 SQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQ----KCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 185

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Human
Match: KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6286])

HSP 1 Score: 56.9954 bits (136), Expect = 6.156e-9
Identity = 36/127 (28.35%), Postives = 63/127 (49.61%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
            S CTL+N +IT +  C   C  D    S +PCLQ+    T   ++ L Y  +    ++     +C+  P C  + +++  +V+      RK   F+CY + E ++  V+L K YS  + +H + WP+
Sbjct:   82 SQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQ----KCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Human
Match: KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6286])

HSP 1 Score: 56.9954 bits (136), Expect = 6.156e-9
Identity = 36/127 (28.35%), Postives = 63/127 (49.61%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
            S CTL+N +IT +  C   C  D    S +PCLQ+    T   ++ L Y  +    ++     +C+  P C  + +++  +V+      RK   F+CY + E ++  V+L K YS  + +H + WP+
Sbjct:   82 SQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQ----KCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Human
Match: KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6286])

HSP 1 Score: 56.9954 bits (136), Expect = 6.156e-9
Identity = 36/127 (28.35%), Postives = 63/127 (49.61%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
            S CTL+N +IT +  C   C  D    S +PCLQ+    T   ++ L Y  +    ++     +C+  P C  + +++  +V+      RK   F+CY + E ++  V+L K YS  + +H + WP+
Sbjct:   82 SQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQ----KCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Human
Match: KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6286])

HSP 1 Score: 56.9954 bits (136), Expect = 6.156e-9
Identity = 36/127 (28.35%), Postives = 63/127 (49.61%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
            S CTL+N +IT +  C   C  D    S +PCLQ+    T   ++ L Y  +    ++     +C+  P C  + +++  +V+      RK   F+CY + E ++  V+L K YS  + +H + WP+
Sbjct:   82 SQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQ----KCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Zebrafish
Match: kcnmb2 (potassium large conductance calcium-activated channel, subfamily M, beta member 2 [Source:ZFIN;Acc:ZDB-GENE-050320-97])

HSP 1 Score: 48.521 bits (114), Expect = 2.547e-6
Identity = 35/132 (26.52%), Postives = 58/132 (43.94%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDN---GIIVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            +TCT++N+++T  I C   C  D    S +PCLQ+   Y  L+          I  LSH  +     S CF      KD+    +++      ++      C+ + +EH+  +LL + Y      H + WPS
Sbjct:   79 TTCTVLNSSLTKEINCSYNCGSDCWRSSKYPCLQV---YVSLN------ATGRIGLLSHNEEMLDVSSECFYVPKCQKDHTAMRVLIQNISDHLKMQQQVRCFHDPSEHQASILLKRIYGSASLLHSLFWPS 201

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Zebrafish
Match: si:ch211-247n2.1 (si:ch211-247n2.1 [Source:ZFIN;Acc:ZDB-GENE-141216-101])

HSP 1 Score: 47.7506 bits (112), Expect = 4.918e-6
Identity = 43/184 (23.37%), Postives = 77/184 (41.85%), Query Frame = 3

Query:  198 KNMPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCS---KDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDNGI---IVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            K   + +    +D    L +S   + LC+ ++  +L   +V  ++       S CT++N+++   I C   C    +  S +PCLQ+   Y  LD          +  LS+  ++  A   CF      K+  +   IV     R++      CY + +E +D VLL + Y  G     + WP+
Sbjct:   32 KRRTVTALKAGEDRAILLGLS---MILCSAMMYFVLGITMVRSYSDSVWTEESNCTVLNSSVVAEINCSYSCGSECRKSSRYPCLQV---YVSLDS-------GKVQRLSYNEEAHEANPECFYIPKCRKEQTLMHTIVMNISERLKMHQQVLCYYDPSEQQDGVLLTRLYGRGAIISSLLWPT 202

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Zebrafish
Match: si:ch211-247n2.1 (si:ch211-247n2.1 [Source:ZFIN;Acc:ZDB-GENE-141216-101])

HSP 1 Score: 47.7506 bits (112), Expect = 5.269e-6
Identity = 43/184 (23.37%), Postives = 77/184 (41.85%), Query Frame = 3

Query:  198 KNMPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCS---KDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDNGI---IVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            K   + +    +D    L +S   + LC+ ++  +L   +V  ++       S CT++N+++   I C   C    +  S +PCLQ+   Y  LD          +  LS+  ++  A   CF      K+  +   IV     R++      CY + +E +D VLL + Y  G     + WP+
Sbjct:   33 KRRTVTALKAGEDRAILLGLS---MILCSAMMYFVLGITMVRSYSDSVWTEESNCTVLNSSVVAEINCSYSCGSECRKSSRYPCLQV---YVSLDS-------GKVQRLSYNEEAHEANPECFYIPKCRKEQTLMHTIVMNISERLKMHQQVLCYYDPSEQQDGVLLTRLYGRGAIISSLLWPT 203

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Xenopus
Match: ENSXETT00000046191.1 (potassium channel subfamily M regulatory beta subunit 2 [Source:NCBI gene;Acc:100493738])

HSP 1 Score: 55.0694 bits (131), Expect = 2.351e-8
Identity = 36/128 (28.12%), Postives = 62/128 (48.44%), Query Frame = 3

Query:  351 SSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
             + CTL+N +IT +  C   C  D    S +PCLQ+        Q+ L Y  +    ++    S+C+  P C  + +++  +VS      RK   F C+ + E ++  V+L K YS  + +H + WP+
Sbjct:   72 ETQCTLMNASITETFNCSFSCGPDCWKISQYPCLQVYVNLNSSGQKVLLYHTEETMKVN----SECSYIPRCGKNYEESLSLVSIIMENFRKHQHFPCFYDPEGNQKNVILTKLYSSDVLFHSLFWPT 195

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Xenopus
Match: ENSXETT00000046181.1 (potassium channel subfamily M regulatory beta subunit 2 [Source:NCBI gene;Acc:100493738])

HSP 1 Score: 54.6842 bits (130), Expect = 2.765e-8
Identity = 36/128 (28.12%), Postives = 62/128 (48.44%), Query Frame = 3

Query:  351 SSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
             + CTL+N +IT +  C   C  D    S +PCLQ+        Q+ L Y  +    ++    S+C+  P C  + +++  +VS      RK   F C+ + E ++  V+L K YS  + +H + WP+
Sbjct:   81 ETQCTLMNASITETFNCSFSCGPDCWKISQYPCLQVYVNLNSSGQKVLLYHTEETMKVN----SECSYIPRCGKNYEESLSLVSIIMENFRKHQHFPCFYDPEGNQKNVILTKLYSSDVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Mouse
Match: Kcnmb2 (potassium large conductance calcium-activated channel, subfamily M, beta member 2 [Source:MGI Symbol;Acc:MGI:1919663])

HSP 1 Score: 54.299 bits (129), Expect = 3.263e-8
Identity = 34/128 (26.56%), Postives = 61/128 (47.66%), Query Frame = 3

Query:  351 SSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
             + C L+N +IT +  C   C  D    S +PCLQ+    T   +  L Y  +    ++     +C+  P C ++ +++  +VS      R+   F CY + E ++  V+L K YS  + +H + WP+
Sbjct:   81 EAQCALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGERLLLYHTEETMKINQ----KCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

Query:  351 SSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
             + C L+N +IT +  C   C  D    S +PCLQ+    T   +  L Y  +    ++     +C+  P C ++ +++  +VS      R+   F CY + E ++  V+L K YS  + +H + WP+
Sbjct:   81 EAQCALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGERLLLYHTEETMKINQ----KCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

Query:  351 SSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
             + C L+N +IT +  C   C  D    S +PCLQ+    T   +  L Y  +    ++     +C+  P C ++ +++  +VS      R+   F CY + E ++  V+L K YS  + +H + WP+
Sbjct:   81 EAQCALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGERLLLYHTEETMKINQ----KCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

Query:  351 SSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
             + C L+N +IT +  C   C  D    S +PCLQ+    T   +  L Y  +    ++     +C+  P C ++ +++  +VS      R+   F CY + E ++  V+L K YS  + +H + WP+
Sbjct:   81 EAQCALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGERLLLYHTEETMKINQ----KCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. UniProt/SwissProt
Match: sp|Q9Y691|KCMB2_HUMAN (Calcium-activated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNMB2 PE=1 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 2.956e-8
Identity = 36/127 (28.35%), Postives = 63/127 (49.61%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
            S CTL+N +IT +  C   C  D    S +PCLQ+    T   ++ L Y  +    ++     +C+  P C  + +++  +V+      RK   F+CY + E ++  V+L K YS  + +H + WP+
Sbjct:   82 SQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQ----KCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. UniProt/SwissProt
Match: sp|Q9CZM9|KCMB2_MOUSE (Calcium-activated potassium channel subunit beta-2 OS=Mus musculus OX=10090 GN=Kcnmb2 PE=2 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 2.282e-7
Identity = 34/128 (26.56%), Postives = 61/128 (47.66%), Query Frame = 3

Query:  351 SSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
             + C L+N +IT +  C   C  D    S +PCLQ+    T   +  L Y  +    ++     +C+  P C ++ +++  +VS      R+   F CY + E ++  V+L K YS  + +H + WP+
Sbjct:   81 EAQCALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGERLLLYHTEETMKINQ----KCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. UniProt/SwissProt
Match: sp|Q811Q0|KCMB2_RAT (Calcium-activated potassium channel subunit beta-2 OS=Rattus norvegicus OX=10116 GN=Kcnmb2 PE=2 SV=1)

HSP 1 Score: 51.6026 bits (122), Expect = 1.787e-6
Identity = 40/157 (25.48%), Postives = 76/157 (48.41%), Query Frame = 3

Query:  282 ALIVGAILIHLVVIPFTHENSFYSSTCT------LINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMRKTPTFACYINAE-HRDEVLLYKFYSIGMFWHCVAWPS 719
            A++V +I+++ + +  T   S+  S  T      L+N +IT +  C   C  D    S +PCLQ+    T   ++ L Y  +    ++     +C+  P C ++ +++  +VS      R+   F CY + E ++  V+L K YS  + +H + WP+
Sbjct:   53 AMMVCSIMMYFL-LGITLLRSYMQSVWTEEAQRALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETMKINQ----KCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPT 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. TrEMBL
Match: A0A4Z2CW83 (Calcium-activated potassium channel subunit beta-2 OS=Schistosoma japonicum OX=6182 GN=EWB00_007000 PE=4 SV=1)

HSP 1 Score: 153.68 bits (387), Expect = 3.558e-42
Identity = 80/183 (43.72%), Postives = 114/183 (62.30%), Query Frame = 3

Query:  240 VKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNIT-TSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVW 785
            +K +Y++C+T+     IV  ILIHLVV P+ HE++F  + C+ ++  I  T +KCENKCSKDRS FPCL++  +Y   ++     ++D+IAT +HY+   CA S C     DN   V +FQ R+R    F CY++A H DE LLYKFY+    +H V WP  L +IS + L ++Y  DKC VW
Sbjct:   22 IKIIYLTCATVITTTFIVECILIHLVVQPYFHESAFTHTNCSFLHAYIVRTDVKCENKCSKDRSKFPCLKVIVQYLSGNKNHTVILFDNIATYNHYKLLGCATSACHHRDMDNTEWVEKFQRRIRLQRHFRCYVHATHEDEALLYKFYTFTSVFHAVFWPISLFLISSICLLLIYIMDKCRVW 204

[Close]

BLAST of Calcium activated potassium channel subunit vs. TrEMBL
Match: A0A5J4NQS7 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0001240 PE=4 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 1.741e-41
Identity = 80/193 (41.45%), Postives = 120/193 (62.18%), Query Frame = 3

Query:  216 SKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITT-SIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVWND 791
            S++C +  +K +Y++C+T+   +LIV  IL+HLV++P+ HE+ F  + C  +   I   +I+CENKCSKDRS F C++IT  Y   D+ + A ++D+IAT  HY    CA S C      N   V  F + +R++PTF CYI+ +H +E LL+KFYS    ++ + WP  LL  S L+LA + S D+C VW D
Sbjct:   51 SQTCREHVLKVVYLTCATVITTSLIVECILLHLVIMPYRHESGFVPTECAYVRARIAGDAIRCENKCSKDRSSFQCIRITVAYRKQDRNYTAILFDNIATYQHYHLLGCATSSCHRQNAANRASVQHFHNMVRQSPTFTCYIHEDHVNEALLHKFYSPITLFNTLFWPLSLLTSSGLLLAAISSYDRCRVWAD 243

[Close]

BLAST of Calcium activated potassium channel subunit vs. TrEMBL
Match: A0A183SZJ1 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS9639 PE=4 SV=1)

HSP 1 Score: 151.754 bits (382), Expect = 2.015e-41
Identity = 73/184 (39.67%), Postives = 117/184 (63.59%), Query Frame = 3

Query:  240 VKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSI-KCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVWN 788
            +K +YI C+     ++IVGAIL+HL+V+PF HE+ F  STC ++ T +   + KCENKCSK+RS FPCL++T  Y  + +     ++D IAT  +YR++ C  S C    ++N  +V+ F++ ++K   F C+I+AEH DE L++KFY     ++ + WP+    +SL  + V+Y+ D+C VW 
Sbjct:   18 IKVIYILCAATLTTSIIVGAILVHLLVLPFLHESGFEPSTCYIVKTELHMPVLKCENKCSKERSAFPCLRVTILYEKMGRNKTGILFDTIATHQNYRRNGCVTSSCHQRWEENIFVVNMFKADLQKRGKFNCFISAEHDDEALMFKFYRPTTIFYALFWPAFTFSVSLFTIIVIYAVDRCKVWR 201

[Close]

BLAST of Calcium activated potassium channel subunit vs. TrEMBL
Match: A0A504YFA9 (Calcium activated potassium channel subunit OS=Fasciola gigantica OX=46835 GN=FGIG_02054 PE=4 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 2.188e-41
Identity = 77/183 (42.08%), Postives = 112/183 (61.20%), Query Frame = 3

Query:  240 VKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNI-TTSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVW 785
            +KF Y++C+T+   + I+  ILIHLVV P+ HE++F  ++CT ++++I   ++KCENKCSKDRS FPCL++   Y          +YD+IAT  HY+   CA S C     DN   V +F+ R++    F CYI+A H DE LL+KFYS    +H V WP  L   S++ ++  Y  D+C VW
Sbjct:   19 LKFTYLTCATVITTSFIIECILIHLVVQPYIHESAFSHTSCTYLHSDIIRQNVKCENKCSKDRSRFPCLKVLVSYYTGGDNHTVVLYDNIATYQHYKYLGCATSSCHHRDTDNTAWVDQFRLRVQHQKHFGCYIHATHEDEALLFKFYSTNTVFHAVFWPVSLFCTSVVCVSCAYVVDRCRVW 201

[Close]

BLAST of Calcium activated potassium channel subunit vs. TrEMBL
Match: A0A4E0RIE4 (Calcium activated potassium channel subunit OS=Fasciola hepatica OX=6192 GN=D915_001494 PE=4 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 4.039e-41
Identity = 77/183 (42.08%), Postives = 112/183 (61.20%), Query Frame = 3

Query:  240 VKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNI-TTSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVW 785
            +KF Y++C+T+   + I+  IL+HLVV P+ HE++F  ++CT ++++I   ++KCENKCSKDRS FPCL++   Y          +YD+IAT  HY+   CA S C     DN   V +F+ R++    F CYI+A H DE LL+KFYS    +H V WP  L   SL+ ++  Y  D+C VW
Sbjct:   19 LKFTYLTCATVITTSFIIECILVHLVVQPYIHESAFSHTSCTYLHSDIIRQNVKCENKCSKDRSRFPCLKVLVSYYTGGDNHTVVLYDNIATYQHYKYLGCATSSCHHRDTDNTAWVDQFRLRVQHQKHFGCYIHATHEDEALLFKFYSTNTVFHAVFWPVSLFCTSLVCVSCAYVVDRCRVW 201

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Cavefish
Match: si:ch211-247n2.1 (calcium-activated potassium channel subunit beta-2 [Source:NCBI gene;Acc:103042220])

HSP 1 Score: 52.373 bits (124), Expect = 1.385e-7
Identity = 35/132 (26.52%), Postives = 62/132 (46.97%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDNGI---IVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            S+CT++N+++ + I C   C  +    S +PCLQ+   Y  L+          +  LSH  ++Q A   CF      KD+ +   +V     +++      CY + +E +D VLL + Y  G  +  + WP+
Sbjct:   81 SSCTVLNSSVISEINCSYSCGSECWKSSRYPCLQV---YVSLNSS------GRVLRLSHNEEAQEANPECFYVPKCRKDHAVMHTLVLNISEQLKTQHQVPCYYDPSEQQDNVLLTRLYGRGAIFSSLLWPT 203

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Cavefish
Match: si:ch211-247n2.1 (calcium-activated potassium channel subunit beta-2 [Source:NCBI gene;Acc:103042220])

HSP 1 Score: 52.373 bits (124), Expect = 1.617e-7
Identity = 35/132 (26.52%), Postives = 62/132 (46.97%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDNGI---IVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            S+CT++N+++ + I C   C  +    S +PCLQ+   Y  L+          +  LSH  ++Q A   CF      KD+ +   +V     +++      CY + +E +D VLL + Y  G  +  + WP+
Sbjct:  112 SSCTVLNSSVISEINCSYSCGSECWKSSRYPCLQV---YVSLNSS------GRVLRLSHNEEAQEANPECFYVPKCRKDHAVMHTLVLNISEQLKTQHQVPCYYDPSEQQDNVLLTRLYGRGAIFSSLLWPT 234

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Cavefish
Match: si:ch211-247n2.1 (calcium-activated potassium channel subunit beta-2 [Source:NCBI gene;Acc:103042220])

HSP 1 Score: 51.9878 bits (123), Expect = 1.905e-7
Identity = 35/132 (26.52%), Postives = 62/132 (46.97%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDNGI---IVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            S+CT++N+++ + I C   C  +    S +PCLQ+   Y  L+          +  LSH  ++Q A   CF      KD+ +   +V     +++      CY + +E +D VLL + Y  G  +  + WP+
Sbjct:  120 SSCTVLNSSVISEINCSYSCGSECWKSSRYPCLQV---YVSLNSS------GRVLRLSHNEEAQEANPECFYVPKCRKDHAVMHTLVLNISEQLKTQHQVPCYYDPSEQQDNVLLTRLYGRGAIFSSLLWPT 242

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Cavefish
Match: kcnmb2 (calcium-activated potassium channel subunit beta-2-like [Source:NCBI gene;Acc:103021848])

HSP 1 Score: 51.6026 bits (122), Expect = 2.033e-7
Identity = 39/161 (24.22%), Postives = 73/161 (45.34%), Query Frame = 3

Query:  267 TLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDN---GIIVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            ++ LC++++  +L   +V  +T       S CT++N+++T  I C   C  D    S +PCLQ+   Y  ++          +  LSH  ++Q   S CF      KD+     ++     +++      C+ + AE +  +LL + Y     +H + WPS
Sbjct:   51 SMVLCSIMMYFVLCITMVRSYTDSVWTEESICTILNSSLTMEINCSYSCGPDCWRSSKYPCLQV---YVSIN------ATGRVGLLSHNEETQDISSECFYVPKCQKDHVAVQAMMVNISEKLKAQQQVRCFYDPAEQQSSILLSRLYGTSAIFHSLFWPS 202

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Cavefish
Match: si:ch211-247n2.1 (calcium-activated potassium channel subunit beta-2 [Source:NCBI gene;Acc:103042220])

HSP 1 Score: 51.6026 bits (122), Expect = 2.298e-7
Identity = 35/132 (26.52%), Postives = 62/132 (46.97%), Query Frame = 3

Query:  354 STCTLINTNITTSIKCENKCSKD---RSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCF---SSTKDNGI---IVSEFQSRMRKTPTFACYIN-AEHRDEVLLYKFYSIGMFWHCVAWPS 719
            S+CT++N+++ + I C   C  +    S +PCLQ+   Y  L+          +  LSH  ++Q A   CF      KD+ +   +V     +++      CY + +E +D VLL + Y  G  +  + WP+
Sbjct:  124 SSCTVLNSSVISEINCSYSCGSECWKSSRYPCLQV---YVSLNSS------GRVLRLSHNEEAQEANPECFYVPKCRKDHAVMHTLVLNISEQLKTQHQVPCYYDPSEQQDNVLLTRLYGRGAIFSSLLWPT 246

[Close]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004674.1 (pep scaffold:Pmarinus_7.0:GL478954:145064:148714:1 gene:ENSPMAG00000004254.1 transcript:ENSPMAT00000004674.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 44.669 bits (104), Expect = 9.007e-6
Identity = 43/159 (27.04%), Postives = 68/159 (42.77%), Query Frame = 3

Query:  222 SCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCS---KDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISP-CFSSTKDNGIIVSEFQSRMR---KTPTFACYINAE-HRDEVLLYK 674
            S A+  V  L +S   L +    + +I    VV P  +      + CT+I+  I   I C  +C    K  S +PCLQ+    T   ++ L +  +   + S    SQC   P C+    D   ++   +S  R   +TP F C+ NA  H D+ L  +
Sbjct:   40 SAAEARVVLLALSMVGLGIAVFFILSIT---VVQPLLNGRGSKEANCTVISAEIPKWIDCAFECGPYCKGVSSYPCLQVYVNVTPWGRKVLLHRDEQSISSS----SQCYQLPKCYRDHADATAVIEPLKSSFRALNRTP-FRCFYNARVHHDDALFSR 190

[Close]

BLAST of Calcium activated potassium channel subunit vs. Planmine SMEST
Match: SMESG000047387.1 (SMESG000047387.1)

HSP 1 Score: 383.645 bits (984), Expect = 2.468e-136
Identity = 197/197 (100.00%), Postives = 197/197 (100.00%), Query Frame = 3

Query:  204 MPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVWNDT 794
            MPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGLLVISLLILAVLYSKDKCNVWNDT
Sbjct:    1 MPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGLLVISLLILAVLYSKDKCNVWNDT 197

[Close]

BLAST of Calcium activated potassium channel subunit vs. Planmine SMEST
Match: SMESG000017226.1 (SMESG000017226.1)

HSP 1 Score: 176.022 bits (445), Expect = 3.565e-54
Identity = 86/195 (44.10%), Postives = 120/195 (61.54%), Query Frame = 3

Query:  207 PIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVWND 791
            P  S++  ++W K +Y++  ++ +   IV  IL+HLV+IP+ HE SF S+ C L  T +   ++CENKCSKDRS F CLQI   Y   ++ F AY+Y+H+ATL H+ K+ CA SPC     DN +IVS F   +++   F C+ + +H  E LLYKFY    F HC  WP  L+V S   L V+Y  DKC VW+D
Sbjct:   28 PSTSRATKENWFKIIYLASISIFVSTFIVVCILMHLVIIPYLHETSFISAQCNLNETRMGDEVRCENKCSKDRSKFKCLQIIVNYRRNNKMFSAYLYEHVATLRHFSKNHCATSPCHKEEIDNYLIVSRFNRDIKRQRNFNCFTSIKHPSEALLYKFYDASTFLHCTLWPLLLIVSSATSLTVIYQIDKCRVWHD 222

[Close]

BLAST of Calcium activated potassium channel subunit vs. Planmine SMEST
Match: SMESG000055809.1 (SMESG000055809.1)

HSP 1 Score: 126.331 bits (316), Expect = 4.026e-35
Identity = 76/209 (36.36%), Postives = 112/209 (53.59%), Query Frame = 3

Query:  204 MPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCSKDRSMFPCLQITAKYTD------LDQE--FLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQ----SRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVW-ND 791
            M  I  +     +KFLYIS  ++++   I+  IL+HL++ P+ HE  F    CT++N +    IKC NKCSK+RS F C  +  KY        L  +  +  Y++D I TL +++  +C ISPC+    DN I    F       +     F CY+N    +EVLLYKFYS   +  C+ WP  L+V+S+ I+ + Y  D+C VW ND
Sbjct:    1 MRKIQNNIRHSVLKFLYISSLSVAVSGFIIECILLHLIISPYGHETQFVDGKCTVLNISTRYGIKCVNKCSKERSKFFCSTVKVKYQSKISLGRLSNQTWYHGYLFDQITTLHNFKDEKCIISPCYKLKLDNYIETRNFLHVHFDHLESNSAFPCYVNRYLTNEVLLYKFYSYETYISCILWPITLIVLSVFIILLCYWIDRCKVWAND 209

[Close]

BLAST of Calcium activated potassium channel subunit vs. Planmine SMEST
Match: SMESG000055809.1 (SMESG000055809.1)

HSP 1 Score: 120.939 bits (302), Expect = 1.787e-32
Identity = 65/183 (35.52%), Postives = 95/183 (51.91%), Query Frame = 3

Query:  204 MPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNITTSIKCENKCSKDRSMFPCLQITAKYTD------LDQE--FLAYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQ----SRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWP 716
            M  I  +     +KFLYIS  ++++   I+  IL+HL++ P+ HE  F    CT++N +    IKC NKCSK+RS F C  +  KY        L  +  +  Y++D I TL +++  +C ISPC+    DN I    F       +     F CY+N    +EVLLYKFYS   +  C+ WP
Sbjct:    1 MRKIQNNIRHSVLKFLYISSLSVAVSGFIIECILLHLIISPYGHETQFVDGKCTVLNISTRYGIKCVNKCSKERSKFFCSTVKVKYQSKISLGRLSNQTWYHGYLFDQITTLHNFKDEKCIISPCYKLKLDNYIETRNFLHVHFDHLESNSAFPCYVNRYLTNEVLLYKFYSYETYISCILWP 183

[Close]

BLAST of Calcium activated potassium channel subunit vs. Planmine SMEST
Match: SMESG000053268.1 (SMESG000053268.1)

HSP 1 Score: 105.145 bits (261), Expect = 5.346e-27
Identity = 62/205 (30.24%), Postives = 100/205 (48.78%), Query Frame = 3

Query:  210 IISKSCAQDWV-KFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYSSTCTLINTNIT------TSIKCENKCSKDRSMFPCLQITAKYT--DLDQEFL--AYVYDHIATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHRDEVLLYKFYSIGMFWHCVAWPSGXXXXXXXXXXXXYSKDKCNVWND 791
            ++   C +  + K +Y+S  T      I+  IL+HL++ P+  E  F  +TC   N++          ++CENKC+KD   FPC+ +   Y   +  Q  L   Y+YD+  T + Y+K +C+ SPC     DN   V  F   +     F+CY N +    VLLYK Y   +  HC+ WP G+ ++ L+ +        C+VW +
Sbjct:    8 VLRNKCNETGISKLIYLSSMTFLTSGFILECILLHLMLTPYLAEQEFEQTTCVYRNSSSRFILLSDLQLRCENKCTKDTGKFPCVWLLVNYVIPNSGQRQLQDGYLYDYYRTYNRYKKQRCSTSPCHLLLSDNIDWVISFDRTLYSKHNFSCYYNTKDHMSVLLYKLYPKSLILHCILWPFGIFIVGLVGITFTALIAGCDVWKN 212

The following BLAST results are available for this feature:

BLAST of Calcium activated potassium channel subunit vs. Ensembl Human
BLAST of Calcium activated potassium channel subunit vs. Ensembl Celegans
BLAST of Calcium activated potassium channel subunit vs. Ensembl Fly
BLAST of Calcium activated potassium channel subunit vs. Ensembl Zebrafish
BLAST of Calcium activated potassium channel subunit vs. Ensembl Xenopus
BLAST of Calcium activated potassium channel subunit vs. Ensembl Mouse
BLAST of Calcium activated potassium channel subunit vs. UniProt/SwissProt
BLAST of Calcium activated potassium channel subunit vs. TrEMBL
BLAST of Calcium activated potassium channel subunit vs. Ensembl Cavefish
BLAST of Calcium activated potassium channel subunit vs. Ensembl Sea Lamprey
BLAST of Calcium activated potassium channel subunit vs. Ensembl Yeast
BLAST of Calcium activated potassium channel subunit vs. Ensembl Nematostella
BLAST of Calcium activated potassium channel subunit vs. Ensembl Medaka
BLAST of Calcium activated potassium channel subunit vs. Planmine SMEST

BLAST of Calcium activated potassium channel subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNMB2	4.518e-9	28.35	potassium calcium-activated channel subfamily M re...	[more]
KCNMB2	6.156e-9	28.35	potassium calcium-activated channel subfamily M re...	[more]
KCNMB2	6.156e-9	28.35	potassium calcium-activated channel subfamily M re...	[more]
KCNMB2	6.156e-9	28.35	potassium calcium-activated channel subfamily M re...	[more]
KCNMB2	6.156e-9	28.35	potassium calcium-activated channel subfamily M re...	[more]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calcium activated potassium channel subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calcium activated potassium channel subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
kcnmb2	2.547e-6	26.52	potassium large conductance calcium-activated chan...	[more]
si:ch211-247n2.1	4.918e-6	23.37	si:ch211-247n2.1 [Source:ZFIN;Acc:ZDB-GENE-141216-...	[more]
si:ch211-247n2.1	5.269e-6	23.37	si:ch211-247n2.1 [Source:ZFIN;Acc:ZDB-GENE-141216-...	[more]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSXETT00000046191.1	2.351e-8	28.13	potassium channel subfamily M regulatory beta subu...	[more]
ENSXETT00000046181.1	2.765e-8	28.13	potassium channel subfamily M regulatory beta subu...	[more]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Kcnmb2	3.263e-8	26.56	potassium large conductance calcium-activated chan...	[more]
Kcnmb2	3.263e-8	26.56	potassium large conductance calcium-activated chan...	[more]
Kcnmb2	3.263e-8	26.56	potassium large conductance calcium-activated chan...	[more]
Kcnmb2	3.263e-8	26.56	potassium large conductance calcium-activated chan...	[more]

BLAST of Calcium activated potassium channel subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3


Match Name	E-value	Identity	Description
sp\|Q9Y691\|KCMB2_HUMAN	2.956e-8	28.35	Calcium-activated potassium channel subunit beta-2...	[more]
sp\|Q9CZM9\|KCMB2_MOUSE	2.282e-7	26.56	Calcium-activated potassium channel subunit beta-2...	[more]
sp\|Q811Q0\|KCMB2_RAT	1.787e-6	25.48	Calcium-activated potassium channel subunit beta-2...	[more]

BLAST of Calcium activated potassium channel subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4Z2CW83	3.558e-42	43.72	Calcium-activated potassium channel subunit beta-2...	[more]
A0A5J4NQS7	1.741e-41	41.45	Uncharacterized protein OS=Paragonimus westermani ...	[more]
A0A183SZJ1	2.015e-41	39.67	Uncharacterized protein OS=Schistocephalus solidus...	[more]
A0A504YFA9	2.188e-41	42.08	Calcium activated potassium channel subunit OS=Fas...	[more]
A0A4E0RIE4	4.039e-41	42.08	Calcium activated potassium channel subunit OS=Fas...	[more]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:ch211-247n2.1	1.385e-7	26.52	calcium-activated potassium channel subunit beta-2...	[more]
si:ch211-247n2.1	1.617e-7	26.52	calcium-activated potassium channel subunit beta-2...	[more]
si:ch211-247n2.1	1.905e-7	26.52	calcium-activated potassium channel subunit beta-2...	[more]
kcnmb2	2.033e-7	24.22	calcium-activated potassium channel subunit beta-2...	[more]
si:ch211-247n2.1	2.298e-7	26.52	calcium-activated potassium channel subunit beta-2...	[more]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000004674.1	9.007e-6	27.04	pep scaffold:Pmarinus_7.0:GL478954:145064:148714:1...	[more]

BLAST of Calcium activated potassium channel subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calcium activated potassium channel subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calcium activated potassium channel subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calcium activated potassium channel subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000047387.1	2.468e-136	100.00	SMESG000047387.1	[more]
SMESG000017226.1	3.565e-54	44.10	SMESG000017226.1	[more]
SMESG000055809.1	4.026e-35	36.36	SMESG000055809.1	[more]
SMESG000055809.1	1.787e-32	35.52	SMESG000055809.1	[more]
SMESG000053268.1	5.346e-27	30.24	SMESG000053268.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030583 ID=SMED30030583|Name=Calcium activated potassium channel subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=860bp
TGAAATTTCACTGATGAAAATTGCAGCATCAAAATTGCTATCAAATATTA
GATCACCAACCAGAAGAGACAAACATTGTTTTGGAAAATTCTATTCTGCT
ATATATTTTAGACGAAACTTTTAAAATTGATTTTAATCGTCGGAAATGAA
ATTATCAACATCAACTTTTGGAGAATAACATAGCAAAATTGACAATCAAA
AATATGCCAATAATATCGAAATCTTGCGCTCAAGACTGGGTGAAATTTCT
TTATATTTCATGTAGCACATTGTCATTATGTGCGCTTATTGTTGGCGCAA
TTCTCATCCATCTCGTAGTCATACCCTTTACACATGAAAATAGTTTTTAT
TCATCCACATGTACATTAATTAATACCAATATCACGACTTCCATTAAATG
CGAGAACAAATGCTCAAAAGACAGATCAATGTTTCCTTGTTTACAAATAA
CTGCTAAATATACGGATCTCGACCAGGAATTTCTGGCTTATGTCTACGAT
CATATAGCTACATTGTCACATTACCGAAAATCTCAGTGTGCAATCAGTCC
TTGTTTTAGCTCGACAAAAGATAATGGAATTATTGTGTCTGAGTTTCAGT
CGAGAATGAGAAAAACTCCAACATTCGCATGTTACATAAATGCTGAACAC
CGAGACGAAGTTTTGCTTTACAAATTTTATTCAATAGGAATGTTTTGGCA
CTGTGTCGCATGGCCTAGCGGTCTTCTAGTAATATCCTTACTTATACTTG
CAGTTCTCTATTCCAAGGATAAATGCAATGTCTGGAATGATACTTGATTA
AATTATTAAATGAATTATTATTTATTTGATTTTGTTTTCTTTTCTTTAAA
AAAGGCTGAT

protein sequence of SMED30030583-orf-1

>SMED30030583-orf-1 ID=SMED30030583-orf-1|Name=SMED30030583-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=198bp
MPIISKSCAQDWVKFLYISCSTLSLCALIVGAILIHLVVIPFTHENSFYS
STCTLINTNITTSIKCENKCSKDRSMFPCLQITAKYTDLDQEFLAYVYDH
IATLSHYRKSQCAISPCFSSTKDNGIIVSEFQSRMRKTPTFACYINAEHR
DEVLLYKFYSIGMFWHCVAWPSGLLVISLLILAVLYSKDKCNVWNDT*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0016020	membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR003930	K_chnl_Ca-activ_BK_bsu
IPR011528	NERD

Vocabulary: **molecular function**
Term	Definition
GO:0015269	calcium-activated potassium channel activity

Vocabulary: **biological process**
Term	Definition
GO:0006813	potassium ion transport
GO:0071805	potassium ion transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003930	Potassium channel, calcium-activated, BK, beta subunit	PFAM	PF03185	CaKB	coord: 26..184 e-value: 2.9E-17 score: 63.0
IPR003930	Potassium channel, calcium-activated, BK, beta subunit	PANTHER	PTHR10258	CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA	coord: 17..190
None	No IPR available	TMHMM	TMhelix		coord: 15..37
None	No IPR available	TMHMM	TMhelix		coord: 164..186

Main menu

Calcium activated potassium channel subunit

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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