Melanocyte proliferating gene 1

Overview
NameMelanocyte proliferating gene 1
Smed IDSMED30030581
Length (bp)1229
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Melanocyte proliferating gene 1 (SMED30030581) t-SNE clustered cells

Violin plots show distribution of expression levels for Melanocyte proliferating gene 1 (SMED30030581) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Melanocyte proliferating gene 1 (SMED30030581) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Melanocyte proliferating gene 1 (SMED30030581) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030581

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30030581SMESG000027795.1 SMESG000027796.1 dd_Smed_v4_1148_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30030581SMESG000027795.1 SMESG000027796.1 dd_Smed_v4_1148_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Human
Match: C12orf10 (chromosome 12 open reading frame 10 [Source:HGNC Symbol;Acc:HGNC:17590])

HSP 1 Score: 321.242 bits (822), Expect = 8.350e-107
Identity = 166/337 (49.26%), Postives = 228/337 (67.66%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSV-CDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP++++++I+RTR+   L +CDIV+DVGG++DP +HR+DHHQ+ F ET  SL+P KPW  KLSSAGLIY++FG ++L +L      +  +  LYDKMYE+FV E+DA+DNG+S   +GEPRY +++ LSARV  +NP WN    D    F++AM+LV  EF+ ++ FY + W PAR +V++A+  R++V  SG I++  +G CPWK H + LE  L  PV                I + IY+D    WRIQC+P  E   F +RL L E WRGLRD+ L ++SGIP  +FVH++GF GG+ T EGAL MA  TL
Sbjct:   46 RIGTHNGTFHCDEALACALLRLLPEYRDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVARLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPV---------------AIFFVIYTDQAGQWRIQCVP-KEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATL 366
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Human
Match: C12orf10 (chromosome 12 open reading frame 10 [Source:HGNC Symbol;Acc:HGNC:17590])

HSP 1 Score: 244.973 bits (624), Expect = 4.174e-78
Identity = 139/335 (41.49%), Postives = 192/335 (57.31%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP++++++I+RTR+   L +CDIV+DVGG++DP +HR+DHHQ+ F ET  SL+P KPW  KLSSAGLIY++FG ++L +L      +  +  LYDK                                                   F++AM+LV  EF+ ++ FY + W PAR +V++A+  R++V  SG I++  +G CPWK H + LE  L  PV                I + IY+D    WRIQC+P  E   F +RL L E WRGLRD+ L ++SGIP  +FVH++GF GG+ T EGAL MA  TL
Sbjct:   22 RIGTHNGTFHCDEALACALLRLLPEYRDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDK-------------------------------------------------AGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPV---------------AIFFVIYTDQAGQWRIQCVP-KEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATL 291
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Human
Match: C12orf10 (chromosome 12 open reading frame 10 [Source:HGNC Symbol;Acc:HGNC:17590])

HSP 1 Score: 181.03 bits (458), Expect = 1.846e-54
Identity = 101/219 (46.12%), Postives = 138/219 (63.01%), Query Frame = 2 
Query:  461 MYEHFVLEIDAIDNGVSV-CDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            MYE+FV E+DA+DNG+S   +GEPRY +++ LSARV  +NP WN    D    F++AM+LV  EF+ ++ FY + W PAR +V++A+  R++V  SG I++  +G CPWK H + LE  L  PV                I + IY+D    WRIQC+P  E   F +RL L E WRGLRD+ L ++SGIP  +FVH++GF GG+ T EGAL MA  TL
Sbjct:    1 MYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVARLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPV---------------AIFFVIYTDQAGQWRIQCVP-KEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATL 203
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Human
Match: C12orf10 (chromosome 12 open reading frame 10 [Source:HGNC Symbol;Acc:HGNC:17590])

HSP 1 Score: 90.5077 bits (223), Expect = 2.210e-21
Identity = 59/128 (46.09%), Postives = 74/128 (57.81%), Query Frame = 2 
Query:  728 KVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            KV  SG I++  +G CPWK H + LE  L  PV                I + IY+D    WRIQC+P  E   F +RL L E WRGLRD+ L ++SGIP  +FVH++GF GG+ T EGAL MA  TL
Sbjct:    9 KVDPSGEIVELAKGACPWKEHLYHLESGLSPPV---------------AIFFVIYTDQAGQWRIQCVP-KEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATL 120
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Celegans
Match: C27H6.8 (UPF0160 protein C27H6.8 [Source:UniProtKB/Swiss-Prot;Acc:O17606])

HSP 1 Score: 323.939 bits (829), Expect = 7.855e-109
Identity = 168/339 (49.56%), Postives = 226/339 (66.67%), Query Frame = 2 
Query:  110 IGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQ---KADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDG--KTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLE 1111
            IGTH+G FHCDE  ACF+LKQLP+FK+  I+RTR+++ L+ CDI++DVGG FD  K R+DHHQ+ F +T ++L  +  +  KLSSAGL+Y ++G+E++ ++     S+  I++ Y ++YE FV  IDAIDNG+S  DG PRY  S NLS+R G  N  WN+    ADE   F++AM+ +G EF   VK+  N WWPARE+++ A+D R+++  SG I+  E GGCPWK HFFD+E   K   DDN             I Y ++SD    +WR+Q IP+ +   F NR+ L   WRGLRDD+LSK SGIP  VFVH +GFIGGN T EGA+ MA K LE
Sbjct:    5 IGTHSGKFHCDEAFACFMLKQLPQFKDHSILRTRDAAQLEKCDIIVDVGGIFDHSKQRYDHHQRGFTDTMRTLE-KLNFDTKLSSAGLVYAHYGREVINQILGGNVSSSMIDLFYHRLYEQFVESIDAIDNGISQYDGVPRYHSSGNLSSRTGQFNSHWNEPENDADER--FQQAMQFIGEEFSRSVKYLANVWWPAREIIEAAVDKRFEIDASGRIILIENGGCPWKEHFFDIEVE-KNIADDN-------------ITYILFSDSTNASWRVQAIPVDKMSSFENRMPLPAAWRGLRDDDLSKESGIPGGVFVHISGFIGGNLTREGAIAMARKALE 326
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Fly
Match: CG11980 (gene:FBgn0037652 transcript:FBtr0081964)

HSP 1 Score: 239.195 bits (609), Expect = 1.801e-75
Identity = 142/348 (40.80%), Postives = 209/348 (60.06%), Query Frame = 2 
Query:   98 SMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSAL-DTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNP---EKPWTIKLSSAGLIYVYFGKEILTELCAKYN----SNIDINILYDKMYEHFVLEIDAIDNGVSVCDG-EPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLE 1111
            S L IGTH+G FHCDE++ACF+LKQL ++K ++I R+R++ AL + CDI++DVGG +D  K  +DHHQ  F ETF S+ P   E    ++LSSAGL+Y ++G+ ++  +  +      S  ++   + ++Y +F+ E+DAIDNGV + +G EP Y IS++LSAR+  +NP W +   D    F +AM+  G EF+D V      W PAR+ V++A+ +   VH +G IL   +  CPWKSH FDLEK  K          G   L        +++ G +WR+  +P++    ++ R  L   WRGL DDEL   + I D  F+H TGFIGG KT E A+ +A K+ E
Sbjct:   10 SPLWIGTHSGTFHCDELVACFMLKQLDEYKNAEIFRSRDNKALKEKCDIIVDVGGVYDHAKKLYDHHQITFKETFSSVRPDVSEDYNVVRLSSAGLVYCHYGERVIQSILQREKGIKLSPENLQTAFIQIYRNFINELDAIDNGVPMFEGVEPIYKISTHLSARIAKLNPSWQETGVDIEDRFRQAMDTAGREFVDNVVEVSCSWIPARDHVREALKNAKNVHPTGEILVL-KNFCPWKSHLFDLEKEYKV--------EGVPKLV-------VFNSGNSWRVAGVPVT-PGSYLGRKFLPTPWRGLMDDELCDKASIKDLEFIHHTGFIGGAKTEEAAMLLAKKSTE 340
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Fly
Match: CG11980 (gene:FBgn0037652 transcript:FBtr0081963)

HSP 1 Score: 238.81 bits (608), Expect = 2.781e-75
Identity = 142/348 (40.80%), Postives = 209/348 (60.06%), Query Frame = 2 
Query:   98 SMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSAL-DTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNP---EKPWTIKLSSAGLIYVYFGKEILTELCAKYN----SNIDINILYDKMYEHFVLEIDAIDNGVSVCDG-EPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLE 1111
            S L IGTH+G FHCDE++ACF+LKQL ++K ++I R+R++ AL + CDI++DVGG +D  K  +DHHQ  F ETF S+ P   E    ++LSSAGL+Y ++G+ ++  +  +      S  ++   + ++Y +F+ E+DAIDNGV + +G EP Y IS++LSAR+  +NP W +   D    F +AM+  G EF+D V      W PAR+ V++A+ +   VH +G IL   +  CPWKSH FDLEK  K          G   L        +++ G +WR+  +P++    ++ R  L   WRGL DDEL   + I D  F+H TGFIGG KT E A+ +A K+ E
Sbjct:   24 SPLWIGTHSGTFHCDELVACFMLKQLDEYKNAEIFRSRDNKALKEKCDIIVDVGGVYDHAKKLYDHHQITFKETFSSVRPDVSEDYNVVRLSSAGLVYCHYGERVIQSILQREKGIKLSPENLQTAFIQIYRNFINELDAIDNGVPMFEGVEPIYKISTHLSARIAKLNPSWQETGVDIEDRFRQAMDTAGREFVDNVVEVSCSWIPARDHVREALKNAKNVHPTGEILVL-KNFCPWKSHLFDLEKEYKV--------EGVPKLV-------VFNSGNSWRVAGVPVT-PGSYLGRKFLPTPWRGLMDDELCDKASIKDLEFIHHTGFIGGAKTEEAAMLLAKKSTE 354
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Fly
Match: CG11980 (gene:FBgn0037652 transcript:FBtr0081962)

HSP 1 Score: 238.81 bits (608), Expect = 2.880e-75
Identity = 142/348 (40.80%), Postives = 209/348 (60.06%), Query Frame = 2 
Query:   98 SMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSAL-DTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNP---EKPWTIKLSSAGLIYVYFGKEILTELCAKYN----SNIDINILYDKMYEHFVLEIDAIDNGVSVCDG-EPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLE 1111
            S L IGTH+G FHCDE++ACF+LKQL ++K ++I R+R++ AL + CDI++DVGG +D  K  +DHHQ  F ETF S+ P   E    ++LSSAGL+Y ++G+ ++  +  +      S  ++   + ++Y +F+ E+DAIDNGV + +G EP Y IS++LSAR+  +NP W +   D    F +AM+  G EF+D V      W PAR+ V++A+ +   VH +G IL   +  CPWKSH FDLEK  K          G   L        +++ G +WR+  +P++    ++ R  L   WRGL DDEL   + I D  F+H TGFIGG KT E A+ +A K+ E
Sbjct:   23 SPLWIGTHSGTFHCDELVACFMLKQLDEYKNAEIFRSRDNKALKEKCDIIVDVGGVYDHAKKLYDHHQITFKETFSSVRPDVSEDYNVVRLSSAGLVYCHYGERVIQSILQREKGIKLSPENLQTAFIQIYRNFINELDAIDNGVPMFEGVEPIYKISTHLSARIAKLNPSWQETGVDIEDRFRQAMDTAGREFVDNVVEVSCSWIPARDHVREALKNAKNVHPTGEILVL-KNFCPWKSHLFDLEKEYKV--------EGVPKLV-------VFNSGNSWRVAGVPVT-PGSYLGRKFLPTPWRGLMDDELCDKASIKDLEFIHHTGFIGGAKTEEAAMLLAKKSTE 353
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Zebrafish
Match: C11H12orf10 (melanocyte proliferating gene 1 [Source:ZFIN;Acc:ZDB-GENE-060312-32])

HSP 1 Score: 353.214 bits (905), Expect = 1.669e-119
Identity = 177/345 (51.30%), Postives = 241/345 (69.86%), Query Frame = 2 
Query:   89 LFSSMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKT-WRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            L    +KIGTHNG FHCDEVLACFLL+QLP++K+++I+R+R++S L  CD+V+DVGG++D  + R+DHHQ+ F E+F S+  +KPW  KLSSAGL+YV++G+ +L +L         + +LYDKMYE FV E+DA+DNG+S  DGE RY ISS +S+RV ++NP WN K  D    F KA+ LVG+EF D++ ++ N W PAR++V +AI  R++V  SG +L  +QGGCPWK H F LEK L+                   I++ +Y D    WR+QC+P +    F NRL LLEEWRGLRDD LS++SGIP+ +FVH+ GFIGGNKT  GAL+MA +TL+ A
Sbjct:   50 LMKMKMKIGTHNGTFHCDEVLACFLLRQLPEYKDAEIVRSRDASVLAECDVVVDVGGEYDHSRQRYDHHQRAFAESFHSVCAQKPWVTKLSSAGLVYVHYGRRVLQQLTHLQEDEPQLEVLYDKMYEGFVEEVDAVDNGISQSDGEQRYTISSTISSRVSYLNPQWNSKEQDTEEGFRKALALVGSEFQDRLLYFTNAWLPARDVVLQAIKSRHQVDVSGQVLLLQQGGCPWKEHLFALEKELQ---------------LQELIKFVLYCDQNGHWRVQCVP-AGPNTFQNRLSLLEEWRGLRDDALSELSGIPECIFVHAGGFIGGNKTQSGALEMARRTLQTA 378
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Zebrafish
Match: C11H12orf10 (melanocyte proliferating gene 1 [Source:ZFIN;Acc:ZDB-GENE-060312-32])

HSP 1 Score: 302.368 bits (773), Expect = 2.289e-100
Identity = 137/282 (48.58%), Postives = 192/282 (68.09%), Query Frame = 2 
Query:   89 LFSSMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKT-WRIQCIP 928
            L    +KIGTHNG FHCDEVLACFLL+QLP++K+++I+R+R++S L  CD+V+DVGG++D  + R+DHHQ+ F E+F S+  +KPW  KLSSAGL+YV++G+ +L +L         + +LYDKMYE FV E+DA+DNG+S  DGE RY ISS +S+RV ++NP WN K  D    F KA+ LVG+EF D++ ++ N W PAR++V +AI  R++V  SG +L  +QGGCPWK H F LEK L+                   I++ +Y D    WR+QC+P
Sbjct:   50 LMKMKMKIGTHNGTFHCDEVLACFLLRQLPEYKDAEIVRSRDASVLAECDVVVDVGGEYDHSRQRYDHHQRAFAESFHSVCAQKPWVTKLSSAGLVYVHYGRRVLQQLTHLQEDEPQLEVLYDKMYEGFVEEVDAVDNGISQSDGEQRYTISSTISSRVSYLNPQWNSKEQDTEEGFRKALALVGSEFQDRLLYFTNAWLPARDVVLQAIKSRHQVDVSGQVLLLQQGGCPWKEHLFALEKELQ---------------LQELIKFVLYCDQNGHWRVQCVP 316
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Zebrafish
Match: C11H12orf10 (melanocyte proliferating gene 1 [Source:ZFIN;Acc:ZDB-GENE-060312-32])

HSP 1 Score: 283.878 bits (725), Expect = 1.188e-93
Identity = 132/281 (46.98%), Postives = 187/281 (66.55%), Query Frame = 2 
Query:   89 LFSSMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKT-WRIQCI 925
            L    +KIGTHNG FHCDEVLACFLL+QLP++K+++I+R+R++S L  CD+V+DVGG++D  + R+DHHQ+ F E+F S+  +KPW  KLSSAGL+YV++G+ +L +L         +     +MYE FV E+DA+DNG+S  DGE RY ISS +S+RV ++NP WN K  D    F KA+ LVG+EF D++ ++ N W PAR++V +AI  R++V  SG +L  +QGGCPWK H F LEK L+                   I++ +Y D    WR+QC+
Sbjct:   22 LMKMKMKIGTHNGTFHCDEVLACFLLRQLPEYKDAEIVRSRDASVLAECDVVVDVGGEYDHSRQRYDHHQRAFAESFHSVCAQKPWVTKLSSAGLVYVHYGRRVLQQLTHLQEDEPQL-----EMYEGFVEEVDAVDNGISQSDGEQRYTISSTISSRVSYLNPQWNSKEQDTEEGFRKALALVGSEFQDRLLYFTNAWLPARDVVLQAIKSRHQVDVSGQVLLLQQGGCPWKEHLFALEKELQ---------------LQELIKFVLYCDQNGHWRVQCV 282
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Zebrafish
Match: C11H12orf10 (melanocyte proliferating gene 1 [Source:ZFIN;Acc:ZDB-GENE-060312-32])

HSP 1 Score: 150.599 bits (379), Expect = 1.214e-43
Identity = 66/133 (49.62%), Postives = 93/133 (69.92%), Query Frame = 2 
Query:  335 EKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYK 730
            +KPW  KLSSAGL+YV++G+ +L +L         + +LYDKMYE FV E+DA+DNG+S  DGE RY ISS +S+RV ++NP WN K  D    F KA+ LVG+EF D++ ++ N W PAR++V +AI  R++
Sbjct:    3 QKPWVTKLSSAGLVYVHYGRRVLQQLTHLQEDEPQLEVLYDKMYEGFVEEVDAVDNGISQSDGEQRYTISSTISSRVSYLNPQWNSKEQDTEEGFRKALALVGSEFQDRLLYFTNAWLPARDVVLQAIKSRHQ 135
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Xenopus
Match: myg1 (chromosome 12 open reading frame 10 [Source:NCBI gene;Acc:594885])

HSP 1 Score: 350.132 bits (897), Expect = 2.506e-118
Identity = 174/336 (51.79%), Postives = 234/336 (69.64%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LACFLL+ +  +++++I+RTR+   L  CD+V+DVGG++DP +HR+DHHQ+ F ET +SL P+KPW  KLSSAGL+Y +FG +IL  L  K   +  I++LYDKMYE+FV EIDAIDNG+S  DG+ RY +++ LSARVGH+NP WN+   D    F+KAMEL G+EF+ ++ FY   W PAR +V++AI  R +V +SG ++   QGGCPWK H F LEK L                   Q++Y +Y D    WR+QC+P +    F+NRL L E+WRGLR D+LS +SGIP  +FVH++GFIGGN+T  GAL+MA K L
Sbjct:   48 QIGTHNGTFHCDEALACFLLRTVEPYRDAEIVRTRDPQLLAQCDVVVDVGGEYDPSRHRYDHHQRSFCETMQSLYPDKPWVTKLSSAGLVYAHFGSQILATLLGKEEEDPIISVLYDKMYENFVEEIDAIDNGISQFDGDQRYSVTTTLSARVGHLNPRWNEPDQDTEAGFKKAMELAGSEFVSRLDFYHRSWLPARALVEEAIRKRIQVDESGEVIVLAQGGCPWKEHLFQLEKELG---------------LEKQVKYVLYPDQSAKWRVQCVP-TGPNTFLNRLSLPEDWRGLRADDLSSVSGIPGCIFVHASGFIGGNETQVGALEMARKAL 367
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Mouse
Match: Myg1 (melanocyte proliferating gene 1 [Source:MGI Symbol;Acc:MGI:1929864])

HSP 1 Score: 318.931 bits (816), Expect = 5.525e-106
Identity = 165/337 (48.96%), Postives = 227/337 (67.36%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSV-CDGEPRYLISSNLSARVGHMNPWWNQ-KADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP++  ++I+RTR+   L +CDIV+DVGG+++P+ HR+DHHQ+ F ET  SL P KPW  KLSSAGL+Y++FG+++L +L      +  ++ +YDKMYE+FV E+DA+DNG+S   +GEPRY +++ LSARV  +NP WNQ   D    F +AM+LV  EF+ ++ FY + W PAR +V++A+  R+KV  SG I++  +GGCPWK H + LE  L   V                I + IY+D    WR+QC+P  E   F +RL L E WRGLRD  L ++SGIP  +FVH++GFIGG+ T EGAL MA  TL
Sbjct:   45 RIGTHNGTFHCDEALACALLRLLPEYANAEIVRTRDPEKLASCDIVVDVGGEYNPQSHRYDHHQRTFTETMSSLCPGKPWQTKLSSAGLVYLHFGRKLLAQLLGTSEEDSVVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYAMTTTLSARVARLNPTWNQPNQDTEAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPKV---------------AITFVIYTDQAGQWRVQCVP-KEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATL 365
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Mouse
Match: Myg1 (melanocyte proliferating gene 1 [Source:MGI Symbol;Acc:MGI:1929864])

HSP 1 Score: 244.588 bits (623), Expect = 4.729e-78
Identity = 138/322 (42.86%), Postives = 191/322 (59.32%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSV-CDGEPRYLISSNLSARVGHMNPWWNQKADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGN 1066
            +IGTHNG FHCDE LAC LL+ LP++  ++I+RTR+   L +CDIV+DVGG+++P+ HR+DHHQ+ F ET  SL P KPW  KLSSAGL+Y++FG+++L +L      +  ++ +YDKMYE+FV E+DA+DNG+S   +GEPRY +++ LSARV  +NP WNQ   +                                         +V  SG I++  +GGCPWK H + LE  L   V                I + IY+D    WR+QC+P  E   F +RL L E WRGLRD  L ++SGIP  +FVH++GFIGG+
Sbjct:   41 RIGTHNGTFHCDEALACALLRLLPEYANAEIVRTRDPEKLASCDIVVDVGGEYNPQSHRYDHHQRTFTETMSSLCPGKPWQTKLSSAGLVYLHFGRKLLAQLLGTSEEDSVVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYAMTTTLSARVARLNPTWNQPNQD----------------------------------------TEVDSSGEIVELAKGGCPWKEHLYHLESELSPKV---------------AITFVIYTDQAGQWRVQCVP-KEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGH 306
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Mouse
Match: Myg1 (melanocyte proliferating gene 1 [Source:MGI Symbol;Acc:MGI:1929864])

HSP 1 Score: 240.736 bits (613), Expect = 3.413e-76
Identity = 137/335 (40.90%), Postives = 190/335 (56.72%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP++  ++I+RTR+   L +CDIV+DVGG+++P+ HR+DHHQ+ F ET  SL P KPW  KLSSAGL+Y++FG+++L +L      +  ++ +YDK                                                   F +AM+LV  EF+ ++ FY + W PAR +V++A+  R+KV  SG I++  +GGCPWK H + LE  L   V                I + IY+D    WR+QC+P  E   F +RL L E WRGLRD  L ++SGIP  +FVH++GFIGG+ T EGAL MA  TL
Sbjct:   42 RIGTHNGTFHCDEALACALLRLLPEYANAEIVRTRDPEKLASCDIVVDVGGEYNPQSHRYDHHQRTFTETMSSLCPGKPWQTKLSSAGLVYLHFGRKLLAQLLGTSEEDSVVDTIYDK-------------------------------------------------AGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPKV---------------AITFVIYTDQAGQWRVQCVP-KEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATL 311
[Close]
BLAST of Melanocyte proliferating gene 1 vs. UniProt/SwissProt
Match: sp|Q58DG1|MYG1_BOVIN (UPF0160 protein MYG1, mitochondrial OS=Bos taurus OX=9913 PE=2 SV=1)

HSP 1 Score: 331.257 bits (848), Expect = 4.737e-110
Identity = 174/337 (51.63%), Postives = 235/337 (69.73%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVC-DGEPRYLISSNLSARVGHMNPWWNQ-KADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP+++E++I+RTR+   L  CDIV+DVGG++DP++HR+DHHQ+ F ET  SL+P KPW  KLSSAGLIY++FG ++L +L      +  +  LYDKMYE+FV E+DA+DNG+S   +GEPRYL+++ LSARV  +NP WNQ   D    F++AM+LV  EF+ ++ FY N W PAR +V++A+  R++V  SG I++ E+GGCPWK H + LE  L         P G        I + IY+D    WR+QC+P  E   F +RL LLE WRGLRD+ L +ISGIP  +FVH++GFIGG++T EGAL MA  TL
Sbjct:   46 RIGTHNGTFHCDEALACALLRLLPEYREAEIVRTRDPEKLAACDIVVDVGGEYDPQRHRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDGMVGTLYDKMYENFVEEVDAVDNGISQWEEGEPRYLLTTTLSARVARLNPTWNQPNQDTEAGFKRAMDLVREEFLQRLDFYQNSWLPARTLVEEALAKRFQVDPSGEIIELEKGGCPWKEHLYQLELGLS--------PAGT-------IAFVIYTDQAGQWRVQCVP-KEPHSFQSRLPLLEPWRGLRDEALDQISGIPGCIFVHASGFIGGHRTREGALSMARATL 366
[Close]
BLAST of Melanocyte proliferating gene 1 vs. UniProt/SwissProt
Match: sp|O17606|YK4P_CAEEL (UPF0160 protein C27H6.8 OS=Caenorhabditis elegans OX=6239 GN=C27H6.8 PE=3 SV=2)

HSP 1 Score: 323.939 bits (829), Expect = 9.992e-108
Identity = 168/339 (49.56%), Postives = 226/339 (66.67%), Query Frame = 2 
Query:  110 IGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQ---KADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDG--KTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLE 1111
            IGTH+G FHCDE  ACF+LKQLP+FK+  I+RTR+++ L+ CDI++DVGG FD  K R+DHHQ+ F +T ++L  +  +  KLSSAGL+Y ++G+E++ ++     S+  I++ Y ++YE FV  IDAIDNG+S  DG PRY  S NLS+R G  N  WN+    ADE   F++AM+ +G EF   VK+  N WWPARE+++ A+D R+++  SG I+  E GGCPWK HFFD+E   K   DDN             I Y ++SD    +WR+Q IP+ +   F NR+ L   WRGLRDD+LSK SGIP  VFVH +GFIGGN T EGA+ MA K LE
Sbjct:    5 IGTHSGKFHCDEAFACFMLKQLPQFKDHSILRTRDAAQLEKCDIIVDVGGIFDHSKQRYDHHQRGFTDTMRTLE-KLNFDTKLSSAGLVYAHYGREVINQILGGNVSSSMIDLFYHRLYEQFVESIDAIDNGISQYDGVPRYHSSGNLSSRTGQFNSHWNEPENDADER--FQQAMQFIGEEFSRSVKYLANVWWPAREIIEAAVDKRFEIDASGRIILIENGGCPWKEHFFDIEVE-KNIADDN-------------ITYILFSDSTNASWRVQAIPVDKMSSFENRMPLPAAWRGLRDDDLSKESGIPGGVFVHISGFIGGNLTREGAIAMARKALE 326
[Close]
BLAST of Melanocyte proliferating gene 1 vs. UniProt/SwissProt
Match: sp|Q9HB07|MYG1_HUMAN (UPF0160 protein MYG1, mitochondrial OS=Homo sapiens OX=9606 GN=C12orf10 PE=1 SV=2)

HSP 1 Score: 321.242 bits (822), Expect = 4.010e-106
Identity = 166/337 (49.26%), Postives = 228/337 (67.66%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSV-CDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP++++++I+RTR+   L +CDIV+DVGG++DP +HR+DHHQ+ F ET  SL+P KPW  KLSSAGLIY++FG ++L +L      +  +  LYDKMYE+FV E+DA+DNG+S   +GEPRY +++ LSARV  +NP WN    D    F++AM+LV  EF+ ++ FY + W PAR +V++A+  R++V  SG I++  +G CPWK H + LE  L  PV                I + IY+D    WRIQC+P  E   F +RL L E WRGLRD+ L ++SGIP  +FVH++GF GG+ T EGAL MA  TL
Sbjct:   46 RIGTHNGTFHCDEALACALLRLLPEYRDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVARLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPV---------------AIFFVIYTDQAGQWRIQCVP-KEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATL 366
[Close]
BLAST of Melanocyte proliferating gene 1 vs. UniProt/SwissProt
Match: sp|Q641W2|MYG1_RAT (UPF0160 protein MYG1, mitochondrial OS=Rattus norvegicus OX=10116 GN=Myg1 PE=1 SV=1)

HSP 1 Score: 318.931 bits (816), Expect = 3.391e-105
Identity = 165/337 (48.96%), Postives = 228/337 (67.66%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSV-CDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP+++ ++I+RTR+   L  CDIV+DVGG+++P++HR+DHHQ+ F ET  SL P KPW  KLSSAGL+Y++FG ++L +L      +  ++ +YDKMYE+FV E+DA+DNG+S   +GEPRY +++ LSARV  +NP WNQ   D    F +AM+LV  EF+ ++ FY + W PAR +V++A+  R+KV  SG I++  +GGCPWK H + LE  L   V                I + IY+D    WR+QC+P  E   F +RL L E WRGLRD+ L ++SGIP  +FVH++GFIGG+ T EGAL MA  TL
Sbjct:   46 RIGTHNGTFHCDEALACALLRLLPEYRNAEIVRTRDPEKLALCDIVVDVGGEYNPQRHRYDHHQRTFTETMSSLCPGKPWQTKLSSAGLVYLHFGHKLLAQLLGTSEEDSVVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVSRLNPTWNQPDQDTEAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPTV---------------AITFVIYTDQAGQWRVQCVP-KEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATL 366
[Close]
BLAST of Melanocyte proliferating gene 1 vs. UniProt/SwissProt
Match: sp|Q9JK81|MYG1_MOUSE (UPF0160 protein MYG1, mitochondrial OS=Mus musculus OX=10090 GN=Myg1 PE=1 SV=1)

HSP 1 Score: 318.931 bits (816), Expect = 3.865e-105
Identity = 165/337 (48.96%), Postives = 227/337 (67.36%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSV-CDGEPRYLISSNLSARVGHMNPWWNQ-KADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +IGTHNG FHCDE LAC LL+ LP++  ++I+RTR+   L +CDIV+DVGG+++P+ HR+DHHQ+ F ET  SL P KPW  KLSSAGL+Y++FG+++L +L      +  ++ +YDKMYE+FV E+DA+DNG+S   +GEPRY +++ LSARV  +NP WNQ   D    F +AM+LV  EF+ ++ FY + W PAR +V++A+  R+KV  SG I++  +GGCPWK H + LE  L   V                I + IY+D    WR+QC+P  E   F +RL L E WRGLRD  L ++SGIP  +FVH++GFIGG+ T EGAL MA  TL
Sbjct:   45 RIGTHNGTFHCDEALACALLRLLPEYANAEIVRTRDPEKLASCDIVVDVGGEYNPQSHRYDHHQRTFTETMSSLCPGKPWQTKLSSAGLVYLHFGRKLLAQLLGTSEEDSVVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYAMTTTLSARVARLNPTWNQPNQDTEAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELSPKV---------------AITFVIYTDQAGQWRVQCVP-KEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMARATL 365
[Close]
BLAST of Melanocyte proliferating gene 1 vs. TrEMBL
Match: A0A3Q3ECQ1 (Melanocyte proliferating gene 1 OS=Hippocampus comes OX=109280 PE=4 SV=1)

HSP 1 Score: 380.178 bits (975), Expect = 3.897e-126
Identity = 189/339 (55.75%), Postives = 252/339 (74.34%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKT-WRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            KIGTHNG FHCDEVLACF L+QLP++K ++I+RTR+ + L  CDIV+DVGG+FDP++HR+DHHQ+ F ETF SL P+KPW  KLSSAGL+Y++FG+ +L +L    + +  + IL+DK+YE+FV E+DAIDNG+S CDGE RY IS+ LSARVGH+NP WN K+ D    F+KA+ LVG EF+D++ FY + W PAR++V++A+++RYKV   G +++F QGGCPWK H F LEK L+               TP  I+Y +YSD    WR+QC+P +    F +RL LLEEWRG+RDD LS++SGI   +FVH+ GFIGGNKT EGAL+MA +TL+ A
Sbjct:   87 KIGTHNGTFHCDEVLACFFLRQLPEYKNAEIVRTRDPAQLACCDIVVDVGGEFDPQRHRYDHHQRTFAETFHSLRPDKPWLTKLSSAGLVYLHFGRRLLAQLTQLKDDDKRLEILFDKLYENFVEEVDAIDNGISQCDGEARYAISTTLSARVGHLNPRWNSKSQDTEEGFKKALALVGDEFLDRLDFYKSSWLPARQVVEEAVNERYKVDPCGQVMEFSQGGCPWKEHLFALEKELQVE-------------TP--IKYVLYSDQNGHWRVQCVP-AGLNTFQSRLPLLEEWRGIRDDALSELSGIEGCIFVHAAGFIGGNKTREGALEMARRTLQAA 409
[Close]
BLAST of Melanocyte proliferating gene 1 vs. TrEMBL
Match: A0A0F8AQ64 (UPF0160 protein MYG1, mitochondrial OS=Larimichthys crocea OX=215358 GN=EH28_02937 PE=4 SV=1)

HSP 1 Score: 375.941 bits (964), Expect = 1.699e-125
Identity = 189/348 (54.31%), Postives = 253/348 (72.70%), Query Frame = 2 
Query:   83 KRLFSSM-LKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            KRL +   +KIGTHNG FHCDEVLACF L+QLP++K+++IIRTRE + L  CD+V+DVGG+FDP+KHR+DHHQ+ F ETF SL PEKPW  KLSSAGL+Y++FG+++L +L      +  + +L+DK+YE+FV E+DAIDNG+S  DGE RY +S+ LSARV H+NP WN K+ D    F KAM++VG EF+D+++FY + W PAR +V+ A+ +R++V  SG +L F QGGCPWK H F LEK L+  +                I++ +Y D    WR+QC+P +    F NRL LLEEWRG+RD+ LSK+SGI D +FVH+ GFIGGNKT EGAL+MA +TL+ A
Sbjct:    6 KRLCTETNMKIGTHNGTFHCDEVLACFFLRQLPEYKDAEIIRTREPAQLAECDVVVDVGGEFDPKKHRYDHHQRTFAETFHSLCPEKPWVTKLSSAGLVYLHFGRQLLAQLTQLKEDDRQLEVLFDKLYENFVEEVDAIDNGISQYDGEARYAVSTTLSARVSHLNPRWNSKSQDTEDGFRKAMKMVGEEFLDRLEFYQSAWLPARTVVENAVKERHQVDPSGEVLLFSQGGCPWKEHLFALEKELQVEMP---------------IKFVLYPDQNGQWRVQCVP-AGLNTFQNRLSLLEEWRGVRDEALSKLSGIKDCIFVHAGGFIGGNKTQEGALEMARRTLQAA 337
[Close]
BLAST of Melanocyte proliferating gene 1 vs. TrEMBL
Match: A0A3B1J7Z6 (Melanocyte proliferating gene 1 OS=Astyanax mexicanus OX=7994 PE=4 SV=1)

HSP 1 Score: 376.326 bits (965), Expect = 2.943e-125
Identity = 187/340 (55.00%), Postives = 250/340 (73.53%), Query Frame = 2 
Query:   98 SMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLE 1111
            S +KIGTH+G FHCDEVLAC+ LKQLP++++++I+RTR+   L+ CDIV+DVGG FDP+KHR+DHHQ+ F ETF SL PEKPW  KLSSAGL+YV+FG+++L+ L      + ++ ILYDKMYE+FV E+DA+DNG+S CDGE RY ++++LSARVG++NP WN ++ D    F+KAM LVG EF D++ +Y N W PAR +V+ A+  R++V  SG I+ F+QGGCPWK H F LEK +K  V                I++ +Y D    WR+QC+P +    F NRL LLEEWRG+RDD LS++SGI   +FVHS+GFIGGNKT EGAL+MA +TL+
Sbjct:   43 STMKIGTHSGSFHCDEVLACYFLKQLPQYQDAEIVRTRDPVVLEQCDIVVDVGGVFDPKKHRYDHHQRSFVETFNSLCPEKPWVTKLSSAGLVYVHFGRQVLSHLTHLQEDSRELGILYDKMYENFVEEVDAVDNGISQCDGEARYTVTTSLSARVGYLNPRWNSESQDTEQGFQKAMSLVGVEFQDRLDYYQNAWLPARVVVETAVQTRHQVDPSGEIVMFDQGGCPWKEHLFTLEKEMKVEVP---------------IKFVLYPDQSGQWRVQCVP-AGLNTFQNRLSLLEEWRGVRDDALSELSGISSCIFVHSSGFIGGNKTKEGALEMARRTLQ 366
[Close]
BLAST of Melanocyte proliferating gene 1 vs. TrEMBL
Match: A0A3Q1B097 (Melanocyte proliferating gene 1 OS=Amphiprion ocellaris OX=80972 PE=4 SV=1)

HSP 1 Score: 376.326 bits (965), Expect = 6.006e-125
Identity = 186/339 (54.87%), Postives = 251/339 (74.04%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            KIGTHNG FHCDEVLACF L+QLP++ +++IIRTR+ + L  CDIV+DVGG+FDP++HR+DHHQ+ F ETF SL PEKPW  KLSSAGL+Y++FG+ +LT+L      +  + +LYDK+YE+FV E+DA+DNG+S C+GE RY +S+ LSARVGH+NP WN K+ D    F KA+++VG EF+D++ FY + W PAR +V++A+  R+++  SG +L F QGGCPWK H F LEK+L+               TP  I++ +Y D    WRIQC+P +    F NRL LLEEWRG+RD+ LS++SGI D +FVH++GFIGGNKT EGAL+MA +TL+ A
Sbjct:   70 KIGTHNGTFHCDEVLACFFLRQLPEYTDAEIIRTRDPAQLAECDIVVDVGGEFDPKRHRYDHHQRTFTETFHSLCPEKPWVTKLSSAGLVYLHFGRRLLTQLTQLKEDDRQLEVLYDKLYENFVEEVDAVDNGISQCEGEARYTVSTTLSARVGHLNPRWNSKSQDTEEGFRKALKMVGEEFIDRLDFYKSSWLPARTVVEEAVKQRHQIDPSGEVLLFSQGGCPWKEHLFALEKDLQVE-------------TP--IKFVLYPDQNGQWRIQCVP-AGLNTFQNRLSLLEEWRGVRDEALSELSGIKDCIFVHASGFIGGNKTQEGALEMARRTLQAA 392
[Close]
BLAST of Melanocyte proliferating gene 1 vs. TrEMBL
Match: A0A3P8SFD6 (Melanocyte proliferating gene 1 OS=Amphiprion percula OX=161767 PE=4 SV=1)

HSP 1 Score: 376.326 bits (965), Expect = 6.412e-125
Identity = 186/339 (54.87%), Postives = 251/339 (74.04%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            KIGTHNG FHCDEVLACF L+QLP++ +++IIRTR+ + L  CDIV+DVGG+FDP++HR+DHHQ+ F ETF SL PEKPW  KLSSAGL+Y++FG+ +LT+L      +  + +LYDK+YE+FV E+DA+DNG+S C+GE RY +S+ LSARVGH+NP WN K+ D    F KA+++VG EF+D++ FY + W PAR +V++A+  R+++  SG +L F QGGCPWK H F LEK+L+               TP  I++ +Y D    WRIQC+P +    F NRL LLEEWRG+RD+ LS++SGI D +FVH++GFIGGNKT EGAL+MA +TL+ A
Sbjct:   70 KIGTHNGTFHCDEVLACFFLRQLPEYTDAEIIRTRDPAQLAECDIVVDVGGEFDPKRHRYDHHQRTFTETFHSLCPEKPWVTKLSSAGLVYLHFGRRLLTQLTQLKEDDRQLEVLYDKLYENFVEEVDAVDNGISQCEGEARYTVSTTLSARVGHLNPRWNSKSQDTEEGFRKALKMVGEEFIDRLDFYKSSWLPARTVVEEAVKQRHQIDPSGEVLLFSQGGCPWKEHLFALEKDLQVE-------------TP--IKFVLYPDQNGQWRIQCVP-AGLNTFQNRLSLLEEWRGVRDEALSELSGIKDCIFVHASGFIGGNKTQEGALEMARRTLQAA 392
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Cavefish
Match: myg1 (chromosome 22 C12orf10 homolog [Source:NCBI gene;Acc:103038060])

HSP 1 Score: 376.326 bits (965), Expect = 1.115e-128
Identity = 187/340 (55.00%), Postives = 250/340 (73.53%), Query Frame = 2 
Query:   98 SMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSD-GKTWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLE 1111
            S +KIGTH+G FHCDEVLAC+ LKQLP++++++I+RTR+   L+ CDIV+DVGG FDP+KHR+DHHQ+ F ETF SL PEKPW  KLSSAGL+YV+FG+++L+ L      + ++ ILYDKMYE+FV E+DA+DNG+S CDGE RY ++++LSARVG++NP WN ++ D    F+KAM LVG EF D++ +Y N W PAR +V+ A+  R++V  SG I+ F+QGGCPWK H F LEK +K  V                I++ +Y D    WR+QC+P +    F NRL LLEEWRG+RDD LS++SGI   +FVHS+GFIGGNKT EGAL+MA +TL+
Sbjct:   43 STMKIGTHSGSFHCDEVLACYFLKQLPQYQDAEIVRTRDPVVLEQCDIVVDVGGVFDPKKHRYDHHQRSFVETFNSLCPEKPWVTKLSSAGLVYVHFGRQVLSHLTHLQEDSRELGILYDKMYENFVEEVDAVDNGISQCDGEARYTVTTSLSARVGYLNPRWNSESQDTEQGFQKAMSLVGVEFQDRLDYYQNAWLPARVVVETAVQTRHQVDPSGEIVMFDQGGCPWKEHLFTLEKEMKVEVP---------------IKFVLYPDQSGQWRVQCVP-AGLNTFQNRLSLLEEWRGVRDDALSELSGISSCIFVHSSGFIGGNKTKEGALEMARRTLQ 366
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001549.1 (pep scaffold:Pmarinus_7.0:GL476528:69460:75057:-1 gene:ENSPMAG00000001402.1 transcript:ENSPMAT00000001549.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 166.777 bits (421), Expect = 1.370e-50
Identity = 70/126 (55.56%), Postives = 99/126 (78.57%), Query Frame = 2 
Query:   83 KRLFSSMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDK 460
            KRL  +M  IGTH+G FHCDEVLACFLL+QLP++K+++++RTR+  AL TCD+V+DVGG++DP +HR+DHHQ+ F ET  SL  EKPW  KLSSAGL+Y++FG+E++T +      + ++  LY+K
Sbjct:   37 KRL-RTMATIGTHDGTFHCDEVLACFLLRQLPRYKDAKVVRTRDPKALATCDVVVDVGGEYDPGRHRYDHHQRSFAETMHSLCAEKPWVTKLSSAGLVYMHFGEEVITSITGLGKEDANVTTLYNK 161
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009410.1 (pep scaffold:Pmarinus_7.0:GL477332:2056997:2058627:1 gene:ENSPMAG00000008512.1 transcript:ENSPMAT00000009410.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 140.969 bits (354), Expect = 1.050e-40
Identity = 83/169 (49.11%), Postives = 113/169 (66.86%), Query Frame = 2 
Query:  614 FEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGK-TWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            F KA+E+VG EF+D++ FY   W PAR++V+ AI  R+KV +SG I++F+ GGCPWK H F LE+ L   +D               I+YAI++D K +WR+QC+P++    F NRL L E WRGLRD+ LS   GIP  VFVHS GFIGG+ T +GAL+MA ++L+ A
Sbjct:    1 FWKAVEMVGAEFLDRLHFYWKAWLPARQLVEMAILSRHKVDESGEIVEFQAGGCPWKEHLFTLEETLS--IDK-------------AIKYAIFTDQKGSWRVQCVPVA-VHSFENRLSLPESWRGLRDEALSSHCGIPGCVFVHSGGFIGGHSTRDGALEMARRSLKAA 153
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Yeast
Match: YER156C_mRNA (Putative protein of unknown function; interacts with Hsp82p and copurifies with Ipl1p; expression is copper responsive and downregulated in strains deleted for MAC1, a copper-responsive transcription factor; similarity to mammalian MYG1 [Source:SGD;Acc:S000000958])

HSP 1 Score: 213.772 bits (543), Expect = 1.104e-66
Identity = 134/353 (37.96%), Postives = 209/353 (59.21%), Query Frame = 2 
Query:   86 RLFSSMLK-IGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSV------CDGEPRYLISS-NLSARVGHMNPWWNQ-KADEHV--CFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGK-TWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTL 1108
            +L S M K I TH+G FH DE LA ++L+ LP+FK+++++R+R     +  DI++DVG ++D  K  FDHHQ+ F ETF      + +  KLSSAGLI+ ++G++I+  +     S+ D+++LYDK+Y+ FV  +DA DNG+S        + EP +  ++ ++   +  MNP WN+  +DE    CF +A E +G  F+  V+ Y   W PA+ +V +AID+R  V KSG I+   Q  CPWK H ++LE+              + N+   QI + +++D    WR+  +P++    F  R GL E  RGLRD+ELS  SG+P  +F+H+ GFIGG K+ E   ++A  +L
Sbjct:    8 KLNSKMSKQICTHSGSFHADESLAVYMLRLLPEFKDAKLVRSRNPKDWEASDILVDVGAQYDGVKF-FDHHQRGFFETF-----NEKYKTKLSSAGLIFKHYGRDIIKTILNNKVSSSDLDLLYDKVYKQFVEALDANDNGISKYTIPKDSNLEPNFRDNAISIPGIISGMNPNWNEDTSDESFDRCFARASEFIGGVFVTLVRGYGQSWLPAKALVAQAIDERMDVDKSGKIIVLPQ-FCPWKEHLYELER--------------EKNIEK-QIEFVLFTDSSGAWRVSTVPINS-TSFQFRRGLPEPLRGLRDEELSTKSGVPGCIFIHAAGFIGGAKSKEAVYELAKMSL 337
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Nematostella
Match: EDO41186 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S559])

HSP 1 Score: 344.739 bits (883), Expect = 3.227e-117
Identity = 179/340 (52.65%), Postives = 241/340 (70.88%), Query Frame = 2 
Query:  107 KIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSL-NPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQK-ADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGK-TWRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            KIGTHNG FHCDEVLAC++LKQLP++  + IIRTR+   L+ CD+V+DV G +D  KHR+DHHQ+ F    ++L + +KPW  KLSSAGL+Y++FG+ +L+++      +  ++ +YDK+YE+ + E+DAIDNGVS  D +PRY+I++NLSARVG++NP WN K  DE   F KA++LVG EFMDKV +Y N W PAR +V+ A+  R++V +SG I +  + GCPWK H FDLEK L   V                I++ IYSD    WR+QC+ +   Q F NRLGLLEEWRG+RDD LSK+SGI   +FVH+TGFIGGN+T EGAL+MA KTL+ +
Sbjct:   12 KIGTHNGTFHCDEVLACYMLKQLPEYSHADIIRTRDPKILEQCDVVVDVSGVYDASKHRYDHHQRSFTGCMQTLTDSQKPWKTKLSSAGLVYLHFGRRVLSQVMQMPEDHQALDKVYDKIYENLIQEVDAIDNGVSQSDEKPRYIITTNLSARVGNLNPKWNDKNMDEEAQFNKALQLVGGEFMDKVLYYKNSWLPARSLVKGAVLHRFEVDESGEIAELAECGCPWKDHLFDLEKELNIEV---------------PIKFVIYSDNSGKWRVQCVSV-RPQSFENRLGLLEEWRGIRDDALSKLSGIQGCIFVHATGFIGGNQTREGALEMARKTLQKS 335
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Nematostella
Match: EDO41185 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S558])

HSP 1 Score: 108.997 bits (271), Expect = 2.441e-28
Identity = 46/96 (47.92%), Postives = 71/96 (73.96%), Query Frame = 2 
Query:  329 NPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKADEHVCF 616
            + +KPW  KLSSAGL+Y++FG+ +L+++      +  ++ +YDK+YE+ + E+DAIDNGVS  D +PRY+I++NLSARVG++NP WN K  +  C 
Sbjct:    6 DSQKPWKTKLSSAGLVYLHFGRRVLSQVMQMPEDHQALDKVYDKIYENLIQEVDAIDNGVSQSDEKPRYIITTNLSARVGNLNPKWNDKNMDEECV 101

HSP 2 Score: 61.6178 bits (148), Expect = 2.182e-11
Identity = 42/67 (62.69%), Postives = 54/67 (80.60%), Query Frame = 2 
Query:  917 QCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            +C+ +   Q F NRLGLLEEWRG+RDD LSK+SGI   +FVH+TGFIGGN+T +GAL+MA KTL+ +
Sbjct:   99 ECVSV-RPQSFENRLGLLEEWRGIRDDALSKLSGIQGCIFVHATGFIGGNQTRKGALEMARKTLQKS 164
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Medaka
Match: myg1 (chromosome 5 C12orf10 homolog [Source:NCBI gene;Acc:101160311])

HSP 1 Score: 368.237 bits (944), Expect = 2.999e-125
Identity = 184/342 (53.80%), Postives = 248/342 (72.51%), Query Frame = 2 
Query:   98 SMLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKA-DEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREMVQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNGDTNLTPYQIRYAIYSDGKT-WRIQCIPLSEKQGFVNXXXXXXXXXXXXDDELSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHA 1117
            S  KIGTHNG FHCDEVLACF L+QLP++ +++I+R+R+ + L  CD+V+DVGG+FDP++HR+DHHQ+ F E+F SL PEKPW  KLSSAGLIY++FG+ +L +L      +  + +LY+K+YE+FV E+DAIDNG+S  DG+ RY ISS LS+RVG++NP WN K+ D    F KAM+LVG EFMD+V FY + W PARE+V+ A+ +R++V  SG ++ F QGGCPWK H FDLE  L+                  QI++ +Y D    WR+QC+P ++   F NRL LLEEWRG+RD+ LS++SGI D +FVH+ GFIGGNK  EGAL+MA +TL+ A
Sbjct:   62 SAKKIGTHNGTFHCDEVLACFFLRQLPEYADAEIVRSRDPAVLAECDVVVDVGGEFDPKRHRYDHHQRGFTESFNSLCPEKPWVTKLSSAGLIYLHFGRRLLAQLMQLKEDDRLVELLYNKLYENFVEEVDAIDNGISQYDGKARYKISSTLSSRVGYLNPRWNSKSQDTEEGFRKAMKLVGEEFMDRVDFYKSSWLPAREVVEAAVKERHQVDPSGEVVLFSQGGCPWKEHLFDLENELQVET---------------QIKFVLYPDQNGHWRVQCVP-ADLHSFQNRLSLLEEWRGIRDEALSELSGIKDCIFVHAGGFIGGNKNQEGALEMARRTLQAA 387
[Close]
BLAST of Melanocyte proliferating gene 1 vs. Planmine SMEST
Match: SMESG000027795.1 (SMESG000027795.1)

HSP 1 Score: 354.755 bits (909), Expect = 2.433e-123
Identity = 169/170 (99.41%), Postives = 170/170 (100.00%), Query Frame = 2 
Query:  101 MLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKADEHV 610
            MLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKADEH+
Sbjct:    1 MLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVIDVGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEILTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSNLSARVGHMNPWWNQKADEHL 170
The following BLAST results are available for this feature:
BLAST of Melanocyte proliferating gene 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
C12orf108.350e-10749.26chromosome 12 open reading frame 10 [Source:HGNC S... [more]
C12orf104.174e-7841.49chromosome 12 open reading frame 10 [Source:HGNC S... [more]
C12orf101.846e-5446.12chromosome 12 open reading frame 10 [Source:HGNC S... [more]
C12orf102.210e-2146.09chromosome 12 open reading frame 10 [Source:HGNC S... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C27H6.87.855e-10949.56UPF0160 protein C27H6.8 [Source:UniProtKB/Swiss-P... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CG119801.801e-7540.80gene:FBgn0037652 transcript:FBtr0081964[more]
CG119802.781e-7540.80gene:FBgn0037652 transcript:FBtr0081963[more]
CG119802.880e-7540.80gene:FBgn0037652 transcript:FBtr0081962[more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
C11H12orf101.669e-11951.30melanocyte proliferating gene 1 [Source:ZFIN;Acc:Z... [more]
C11H12orf102.289e-10048.58melanocyte proliferating gene 1 [Source:ZFIN;Acc:Z... [more]
C11H12orf101.188e-9346.98melanocyte proliferating gene 1 [Source:ZFIN;Acc:Z... [more]
C11H12orf101.214e-4349.62melanocyte proliferating gene 1 [Source:ZFIN;Acc:Z... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
myg12.506e-11851.79chromosome 12 open reading frame 10 [Source:NCBI g... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Myg15.525e-10648.96melanocyte proliferating gene 1 [Source:MGI Symbol... [more]
Myg14.729e-7842.86melanocyte proliferating gene 1 [Source:MGI Symbol... [more]
Myg13.413e-7640.90melanocyte proliferating gene 1 [Source:MGI Symbol... [more]
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BLAST of Melanocyte proliferating gene 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q58DG1|MYG1_BOVIN4.737e-11051.63UPF0160 protein MYG1, mitochondrial OS=Bos taurus ... [more]
sp|O17606|YK4P_CAEEL9.992e-10849.56UPF0160 protein C27H6.8 OS=Caenorhabditis elegans ... [more]
sp|Q9HB07|MYG1_HUMAN4.010e-10649.26UPF0160 protein MYG1, mitochondrial OS=Homo sapien... [more]
sp|Q641W2|MYG1_RAT3.391e-10548.96UPF0160 protein MYG1, mitochondrial OS=Rattus norv... [more]
sp|Q9JK81|MYG1_MOUSE3.865e-10548.96UPF0160 protein MYG1, mitochondrial OS=Mus musculu... [more]
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BLAST of Melanocyte proliferating gene 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3Q3ECQ13.897e-12655.75Melanocyte proliferating gene 1 OS=Hippocampus com... [more]
A0A0F8AQ641.699e-12554.31UPF0160 protein MYG1, mitochondrial OS=Larimichthy... [more]
A0A3B1J7Z62.943e-12555.00Melanocyte proliferating gene 1 OS=Astyanax mexica... [more]
A0A3Q1B0976.006e-12554.87Melanocyte proliferating gene 1 OS=Amphiprion ocel... [more]
A0A3P8SFD66.412e-12554.87Melanocyte proliferating gene 1 OS=Amphiprion perc... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
myg11.115e-12855.00chromosome 22 C12orf10 homolog [Source:NCBI gene;A... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000001549.11.370e-5055.56pep scaffold:Pmarinus_7.0:GL476528:69460:75057:-1 ... [more]
ENSPMAT00000009410.11.050e-4049.11pep scaffold:Pmarinus_7.0:GL477332:2056997:2058627... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
YER156C_mRNA1.104e-6637.96Putative protein of unknown function; interacts wi... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO411863.227e-11752.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411852.441e-2847.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
myg12.999e-12553.80chromosome 5 C12orf10 homolog [Source:NCBI gene;Ac... [more]
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BLAST of Melanocyte proliferating gene 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000027795.12.433e-12399.41SMESG000027795.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030581 ID=SMED30030581|Name=Melanocyte proliferating gene 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1229bp
TCCATTTTTATTTTGTTTAAATTTATATTTAATATCCGTGTTTTCAATAT
ATTCATTTTTTATTATTTAGTTAACAATTTAGAAAAGATTATTTTCAAGT
ATGCTGAAGATAGGTACTCATAATGGAGTTTTTCACTGTGATGAAGTCTT
GGCATGTTTTTTACTTAAACAACTACCGAAATTTAAAGAAAGTCAAATAA
TAAGAACTAGAGAGTCGTCTGCTTTAGACACCTGTGATATCGTTATTGAC
GTCGGAGGAAAATTTGATCCAGAAAAACATAGATTTGATCATCACCAAAA
AGATTTCAATGAAACTTTTAAAAGTTTAAACCCTGAAAAACCATGGACCA
TAAAATTAAGTAGTGCCGGTTTAATATATGTTTATTTTGGTAAAGAAATC
TTAACTGAGTTATGTGCAAAATATAATTCAAATATAGATATTAATATTTT
ATACGATAAAATGTATGAACATTTTGTATTAGAAATTGATGCTATCGATA
ATGGTGTTAGTGTATGTGATGGTGAACCACGTTATTTAATCTCATCCAAT
TTGAGTGCTCGAGTTGGACATATGAATCCGTGGTGGAATCAAAAAGCCGA
TGAACATGTTTGTTTTGAAAAAGCTATGGAACTAGTTGGTACTGAATTTA
TGGACAAAGTAAAGTTTTATGTTAATTGTTGGTGGCCTGCCAGAGAAATG
GTACAGAAAGCAATTGATGATCGTTATAAAGTCCATAAATCCGGCATAAT
TTTAAAATTTGAACAAGGAGGCTGTCCTTGGAAAAGTCATTTCTTTGACC
TAGAAAAGAACTTGAAAGCACCAGTCGATGATAATAAACACCCAAATGGA
GACACCAATTTAACCCCATATCAAATTAGATACGCAATATATTCCGATGG
GAAAACTTGGCGAATACAATGTATTCCACTTAGTGAAAAACAAGGATTTG
TTAACAGGCTAGGATTACTTGAGGAATGGAGAGGATTAAGAGATGATGAG
CTATCAAAAATATCGGGTATTCCTGATACTGTATTTGTGCATTCTACTGG
ATTTATCGGCGGAAACAAAACCTATGAAGGTGCCTTACAAATGGCTCTAA
AAACTCTTGAGCATGCAAATTTAATATAAATGTTTTTAAATATAATATTT
ATTTTAGAAAATAACTCGATTGTATTTATATTTAAACAAAAATAATGCCA
TGTAAATTTTACATTTCTTTAGAATTGAG
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protein sequence of SMED30030581-orf-1

>SMED30030581-orf-1 ID=SMED30030581-orf-1|Name=SMED30030581-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=343bp
MLKIGTHNGVFHCDEVLACFLLKQLPKFKESQIIRTRESSALDTCDIVID
VGGKFDPEKHRFDHHQKDFNETFKSLNPEKPWTIKLSSAGLIYVYFGKEI
LTELCAKYNSNIDINILYDKMYEHFVLEIDAIDNGVSVCDGEPRYLISSN
LSARVGHMNPWWNQKADEHVCFEKAMELVGTEFMDKVKFYVNCWWPAREM
VQKAIDDRYKVHKSGIILKFEQGGCPWKSHFFDLEKNLKAPVDDNKHPNG
DTNLTPYQIRYAIYSDGKTWRIQCIPLSEKQGFVNRLGLLEEWRGLRDDE
LSKISGIPDTVFVHSTGFIGGNKTYEGALQMALKTLEHANLI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005739mitochondrion
GO:0070062extracellular exosome
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR003226Met-dep_prot_hydro
Vocabulary: biological process
TermDefinition
GO:0035641locomotory exploration behavior
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003226Metal-dependent protein hydrolasePFAMPF03690UPF0160coord: 3..336
e-value: 1.4E-128
score: 429.1
IPR003226Metal-dependent protein hydrolasePANTHERPTHR11215METAL DEPENDENT HYDROLASE - RELATEDcoord: 3..337
NoneNo IPR availablePANTHERPTHR11215:SF1UPF0160 PROTEIN MYG1, MITOCHONDRIALcoord: 3..337