Ankyrin repeat and FYVE domain containing 1

Overview


Name	Ankyrin repeat and FYVE domain containing 1
Smed ID	SMED30030576
Length (bp)	4215

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ankyrin repeat and FYVE domain containing 1 (SMED30030576) t-SNE clustered cells

Violin plots show distribution of expression levels for Ankyrin repeat and FYVE domain containing 1 (SMED30030576) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ankyrin repeat and FYVE domain containing 1 (SMED30030576) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030576

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
neoblast	SMED30030576	h1SMcG0006558	dd_Smed_v4_13446_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30030576	h1SMcG0006558	Contig11424	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
neuron	SMED30030576	h1SMcG0006558	Contig11424	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30030576	h1SMcG0006558	Contig11424	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30030576	h1SMcG0006558	Contig11424	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016

Note: Hover over icons to view figure legend

Homology

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Human
Match: ANKFY1 (ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763])

HSP 1 Score: 440.269 bits (1131), Expect = 1.893e-132
Identity = 253/652 (38.80%), Postives = 370/652 (56.75%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            ++ L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA       +V  +C  GAD ++      ++G    N PLW+AL N   DIA  LV  G D   W         QTLLHR I E  E  A FLI  GCD  S      P    +N E      +G TPLH+A   GLE  V+ LL     +VN Q+A G T +H+A+  +H  V+  LL     ++L++RD QG TPF  AM   N K+A +IL+    AA+++DN GRNFLHVAVQ  + E+V FLI V+AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ LHIL    +EN   IF L L+  P +P+D+ DA G+T L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  +F +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC +CF+ L  G
Sbjct:  540 SVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPD----EKG----NPPLWLALANNLEDIASTLVRHGCDATCWGPG-PGGCLQTLLHRAIDENNEPTACFLIRSGCDVNS------PRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGA-NVNAQDAEGRTPIHVAISSQH-GVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1166

HSP 2 Score: 234.572 bits (597), Expect = 5.017e-62
Identity = 285/1106 (25.77%), Postives = 481/1106 (43.49%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKD-----FNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNA-----NRGLLMDLALGKKQNKEILKTT-----HRCKGRKVNSDKQL---TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQS--LLHLAVKKGNIEAVQFLIKIGCDINVRSINK----MTPLLLATEKSNIDIVRILCLSGADPNIT----SNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWS------IHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIS---TMENKNPSNSISNYESNNHYI---EGNTPLHMACQ-MGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAAR---SILQYHPQAADEIDNLGRNFLHVAV 3232
            L KH  LL+QEY K+  K    + +   L   +   S+ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ +E++L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A        A+ ++ +  I   L+Q GA+                 NM  +   RT L ++I++GNE V   +L   +C  ++        + K    S               LWLA+      +H+ +  D     F D V +    +F        LI+  +      D+ TGN ++      G E AA+F+  A N                     VN  N + E+  H A  + L NL   LLQ GA+PN+     +                       L K++     + + ++ QT                    P   +M I  +  H   +S+ + +K+NA     N  ++ D +L   +++ +L        H    + + S   +     D  T  H+A++ ++ K   LF+   E +  +N    D  GE+   L + N L  V D I  R           D  V DE+    L LA+     +    L++ GCD             T L  A +++N      L  SG D N      +N   +E   +   PL +A +    +    L+E GA+V+         IH   + +  ++ + ++   +   N    +G    +   T +N   + +I   ES        +G   LH+A Q   +ESV+  +     ++  VQ+A+  T LHLAV+   E ++ +LL    K+N   +  Q      TA+ L+ Q+      S+L  +      +D  G N LH+AV
Sbjct:    9 LEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP----------------NMQ-DSKGRTPLHVSIMAGNEYVFSQLL---QCKQLD-------LELKDHEGST-------------ALWLAV------QHITVSSDQSVNPFED-VPVVNGTSFDENSFAARLIQRGSHTDA-PDTATGNCLLQRAAGAGNEAAALFL--ATNGAH------------------VNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALP----------------------LPKEAASLTSLADSVHLQT--------------------PL--HMAIAYN--HPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSA-LFLL--EHQADINVRTQD--GETALQLAIRNQLPLVVDAICTR---------GADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQ------TALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 980

HSP 3 Score: 71.2478 bits (173), Expect = 1.295e-11
Identity = 98/430 (22.79%), Postives = 174/430 (40.47%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNI-----------TSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNI------------RVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N R+    TPL  A      ++   L   GA+PN+            +++ S    + L  PL +A+     D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA++ +   V+  +       ++S+ D +G+ P   A+  + +  A +++++   A       G   +  LH A+   N     FLI+   ++N               +D    TPLHLA   G  E+ ++ L+  GAN+  +  E +  +H+A+  +   II  L+ +     + +D +  TP   A+   N    + +L   S   +  + KG N LH+   N
Sbjct:  476 FLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICT--RGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDG--QTPLHLAASWGL-EETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQN 881

HSP 4 Score: 64.6994 bits (156), Expect = 1.395e-9
Identity = 118/462 (25.54%), Postives = 184/462 (39.83%), Query Frame = 2

Query: 2648 VALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK-------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            +AL+     IA  LV   ADVDM      D    +LLH+ I      AA FLI  G   +  +    + P + ++ Y S  H  +                         G TPLH++   G E V   LL   ++D+ +++  G T+L LAV+                 ++++   Q   PF        T+ +  N  AAR I +  H  A D     G   L  A    N  A  FL    A++N R K  +  TPLH A   G   +L   L+  GAN   +T E                    Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+++   L V A+  +GA +   + +G
Sbjct:  262 LALSRRLESIATTLVSHKADVDM-----VDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQ-----------------HITVSSDQSVNPFEDVPVVNGTSFD-ENSFAARLIQRGSHTDAPDTAT--GNCLLQRAAGAGNEAAALFLATNGAHVNHRNK--WGETPLHTACRHGLA-NLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTQD--GETALQL-AIRNQLPLVVDAICTRGADMSVPDEKG 688

HSP 5 Score: 56.225 bits (134), Expect = 5.468e-7
Identity = 57/210 (27.14%), Postives = 90/210 (42.86%), Query Frame = 2

Query: 3011 LHLAVKF-RHEAVLTHLLNPKYKL--NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLA-VIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENIL 3628
            LH A+K  R + V  +L+    +L   L+  DH G      A+    +  A +++  H    D +D  G + LH  +Q  +  A  FLI+  A +N     A Q TPLHL  +  + +                        H A V+ E   I   LL+ GA+ + QD+K  TPLH+++  GN  +   LL      ++ K+ +G   L
Sbjct:  222 LHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVS-HKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGA-QETPLHLVALYSSKK------------------------HSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTAL 405

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Query: 2165 TIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            ++ L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA       +V  +C  GAD ++      ++G    N PLW+AL N   DIA  LV  G D   W         QTLLHR I E  E  A FLI  GCD  S      P    +N E      +G TPLH+A   GLE  V+ LL     +VN Q+A G T +H+A+  +H  V+  LL     ++L++RD QG TPF  AM   N K+A +IL+    AA+++DN GRNFLHVAVQ  + E+V FLI V+AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ LHIL    +EN   IF L L+  P +P+D+ DA G+T L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  +F +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC +CF+ L  G
Sbjct:  540 SVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPD----EKG----NPPLWLALANNLEDIASTLVRHGCDATCWGPG-PGGCLQTLLHRAIDENNEPTACFLIRSGCDVNS------PRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGA-NVNAQDAEGRTPIHVAISSQH-GVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1166

HSP 2 Score: 234.572 bits (597), Expect = 5.017e-62
Identity = 285/1106 (25.77%), Postives = 481/1106 (43.49%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKD-----FNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNA-----NRGLLMDLALGKKQNKEILKTT-----HRCKGRKVNSDKQL---TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQS--LLHLAVKKGNIEAVQFLIKIGCDINVRSINK----MTPLLLATEKSNIDIVRILCLSGADPNIT----SNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWS------IHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIS---TMENKNPSNSISNYESNNHYI---EGNTPLHMACQ-MGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAAR---SILQYHPQAADEIDNLGRNFLHVAV 3232
            L KH  LL+QEY K+  K    + +   L   +   S+ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ +E++L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A        A+ ++ +  I   L+Q GA+                 NM  +   RT L ++I++GNE V   +L   +C  ++        + K    S               LWLA+      +H+ +  D     F D V +    +F        LI+  +      D+ TGN ++      G E AA+F+  A N                     VN  N + E+  H A  + L NL   LLQ GA+PN+     +                       L K++     + + ++ QT                    P   +M I  +  H   +S+ + +K+NA     N  ++ D +L   +++ +L        H    + + S   +     D  T  H+A++ ++ K   LF+   E +  +N    D  GE+   L + N L  V D I  R           D  V DE+    L LA+     +    L++ GCD             T L  A +++N      L  SG D N      +N   +E   +   PL +A +    +    L+E GA+V+         IH   + +  ++ + ++   +   N    +G    +   T +N   + +I   ES        +G   LH+A Q   +ESV+  +     ++  VQ+A+  T LHLAV+   E ++ +LL    K+N   +  Q      TA+ L+ Q+      S+L  +      +D  G N LH+AV
Sbjct:    9 LEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP----------------NMQ-DSKGRTPLHVSIMAGNEYVFSQLL---QCKQLD-------LELKDHEGST-------------ALWLAV------QHITVSSDQSVNPFED-VPVVNGTSFDENSFAARLIQRGSHTDA-PDTATGNCLLQRAAGAGNEAAALFL--ATNGAH------------------VNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALP----------------------LPKEAASLTSLADSVHLQT--------------------PL--HMAIAYN--HPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSA-LFLL--EHQADINVRTQD--GETALQLAIRNQLPLVVDAICTR---------GADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQ------TALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 980

HSP 3 Score: 71.2478 bits (173), Expect = 1.295e-11
Identity = 98/430 (22.79%), Postives = 174/430 (40.47%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNI-----------TSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNI------------RVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N R+    TPL  A      ++   L   GA+PN+            +++ S    + L  PL +A+     D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA++ +   V+  +       ++S+ D +G+ P   A+  + +  A +++++   A       G   +  LH A+   N     FLI+   ++N               +D    TPLHLA   G  E+ ++ L+  GAN+  +  E +  +H+A+  +   II  L+ +     + +D +  TP   A+   N    + +L   S   +  + KG N LH+   N
Sbjct:  476 FLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICT--RGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDG--QTPLHLAASWGL-EETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQN 881

HSP 4 Score: 64.6994 bits (156), Expect = 1.395e-9
Identity = 118/462 (25.54%), Postives = 184/462 (39.83%), Query Frame = 2

Query: 2648 VALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK-------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            +AL+     IA  LV   ADVDM      D    +LLH+ I      AA FLI  G   +  +    + P + ++ Y S  H  +                         G TPLH++   G E V   LL   ++D+ +++  G T+L LAV+                 ++++   Q   PF        T+ +  N  AAR I +  H  A D     G   L  A    N  A  FL    A++N R K  +  TPLH A   G   +L   L+  GAN   +T E                    Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+++   L V A+  +GA +   + +G
Sbjct:  262 LALSRRLESIATTLVSHKADVDM-----VDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQ-----------------HITVSSDQSVNPFEDVPVVNGTSFD-ENSFAARLIQRGSHTDAPDTAT--GNCLLQRAAGAGNEAAALFLATNGAHVNHRNK--WGETPLHTACRHGLA-NLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTQD--GETALQL-AIRNQLPLVVDAICTRGADMSVPDEKG 688

HSP 5 Score: 56.225 bits (134), Expect = 5.468e-7
Identity = 57/210 (27.14%), Postives = 90/210 (42.86%), Query Frame = 2

Query: 3011 LHLAVKF-RHEAVLTHLLNPKYKL--NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLA-VIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENIL 3628
            LH A+K  R + V  +L+    +L   L+  DH G      A+    +  A +++  H    D +D  G + LH  +Q  +  A  FLI+  A +N     A Q TPLHL  +  + +                        H A V+ E   I   LL+ GA+ + QD+K  TPLH+++  GN  +   LL      ++ K+ +G   L
Sbjct:  222 LHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVS-HKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGA-QETPLHLVALYSSKK------------------------HSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTAL 405

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Human
Match: ANKFY1 (ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763])

HSP 1 Score: 439.884 bits (1130), Expect = 5.617e-132
Identity = 253/652 (38.80%), Postives = 370/652 (56.75%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            ++ L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA       +V  +C  GAD ++      ++G    N PLW+AL N   DIA  LV  G D   W         QTLLHR I E  E  A FLI  GCD  S      P    +N E      +G TPLH+A   GLE  V+ LL     +VN Q+A G T +H+A+  +H  V+  LL     ++L++RD QG TPF  AM   N K+A +IL+    AA+++DN GRNFLHVAVQ  + E+V FLI V+AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ LHIL    +EN   IF L L+  P +P+D+ DA G+T L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  +F +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC +CF+ L  G
Sbjct:  582 SVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPD----EKG----NPPLWLALANNLEDIASTLVRHGCDATCWGPG-PGGCLQTLLHRAIDENNEPTACFLIRSGCDVNS------PRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGA-NVNAQDAEGRTPIHVAISSQH-GVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1208

HSP 2 Score: 234.572 bits (597), Expect = 5.717e-62
Identity = 285/1106 (25.77%), Postives = 481/1106 (43.49%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKD-----FNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNA-----NRGLLMDLALGKKQNKEILKTT-----HRCKGRKVNSDKQL---TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQS--LLHLAVKKGNIEAVQFLIKIGCDINVRSINK----MTPLLLATEKSNIDIVRILCLSGADPNIT----SNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWS------IHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIS---TMENKNPSNSISNYESNNHYI---EGNTPLHMACQ-MGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAAR---SILQYHPQAADEIDNLGRNFLHVAV 3232
            L KH  LL+QEY K+  K    + +   L   +   S+ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ +E++L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A        A+ ++ +  I   L+Q GA+                 NM  +   RT L ++I++GNE V   +L   +C  ++        + K    S               LWLA+      +H+ +  D     F D V +    +F        LI+  +      D+ TGN ++      G E AA+F+  A N                     VN  N + E+  H A  + L NL   LLQ GA+PN+     +                       L K++     + + ++ QT                    P   +M I  +  H   +S+ + +K+NA     N  ++ D +L   +++ +L        H    + + S   +     D  T  H+A++ ++ K   LF+   E +  +N    D  GE+   L + N L  V D I  R           D  V DE+    L LA+     +    L++ GCD             T L  A +++N      L  SG D N      +N   +E   +   PL +A +    +    L+E GA+V+         IH   + +  ++ + ++   +   N    +G    +   T +N   + +I   ES        +G   LH+A Q   +ESV+  +     ++  VQ+A+  T LHLAV+   E ++ +LL    K+N   +  Q      TA+ L+ Q+      S+L  +      +D  G N LH+AV
Sbjct:   51 LEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP----------------NMQ-DSKGRTPLHVSIMAGNEYVFSQLL---QCKQLD-------LELKDHEGST-------------ALWLAV------QHITVSSDQSVNPFED-VPVVNGTSFDENSFAARLIQRGSHTDA-PDTATGNCLLQRAAGAGNEAAALFL--ATNGAH------------------VNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALP----------------------LPKEAASLTSLADSVHLQT--------------------PL--HMAIAYN--HPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSA-LFLL--EHQADINVRTQD--GETALQLAIRNQLPLVVDAICTR---------GADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQ------TALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 1022

HSP 3 Score: 71.633 bits (174), Expect = 9.995e-12
Identity = 98/430 (22.79%), Postives = 174/430 (40.47%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNI-----------TSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNI------------RVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N R+    TPL  A      ++   L   GA+PN+            +++ S    + L  PL +A+     D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA++ +   V+  +       ++S+ D +G+ P   A+  + +  A +++++   A       G   +  LH A+   N     FLI+   ++N               +D    TPLHLA   G  E+ ++ L+  GAN+  +  E +  +H+A+  +   II  L+ +     + +D +  TP   A+   N    + +L   S   +  + KG N LH+   N
Sbjct:  518 FLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICT--RGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDG--QTPLHLAASWGL-EETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQN 923

HSP 4 Score: 64.6994 bits (156), Expect = 1.546e-9
Identity = 116/453 (25.61%), Postives = 180/453 (39.74%), Query Frame = 2

Query: 2675 IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK-------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            IA  LV   ADVDM      D    +LLH+ I      AA FLI  G   +  +    + P + ++ Y S  H  +                         G TPLH++   G E V   LL   ++D+ +++  G T+L LAV+                 ++++   Q   PF        T+ +  N  AAR I +  H  A D     G   L  A    N  A  FL    A++N R K  +  TPLH A   G   +L   L+  GAN   +T E                    Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+++   L V A+  +GA +   + +G
Sbjct:  313 IATTLVSHKADVDM-----VDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQ-----------------HITVSSDQSVNPFEDVPVVNGTSFD-ENSFAARLIQRGSHTDAPDTAT--GNCLLQRAAGAGNEAAALFLATNGAHVNHRNK--WGETPLHTACRHGLA-NLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTQD--GETALQL-AIRNQLPLVVDAICTRGADMSVPDEKG 730

HSP 5 Score: 56.225 bits (134), Expect = 5.999e-7
Identity = 57/210 (27.14%), Postives = 90/210 (42.86%), Query Frame = 2

Query: 3011 LHLAVKF-RHEAVLTHLLNPKYKL--NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLA-VIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENIL 3628
            LH A+K  R + V  +L+    +L   L+  DH G      A+    +  A +++  H    D +D  G + LH  +Q  +  A  FLI+  A +N     A Q TPLHL  +  + +                        H A V+ E   I   LL+ GA+ + QD+K  TPLH+++  GN  +   LL      ++ K+ +G   L
Sbjct:  264 LHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVS-HKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGA-QETPLHLVALYSSKK------------------------HSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTAL 447

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Human
Match: ANKFY1 (ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763])

HSP 1 Score: 435.647 bits (1119), Expect = 8.495e-131
Identity = 253/653 (38.74%), Postives = 370/653 (56.66%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINV-RSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            ++ L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINV R+ +  T L LA       +V  +C  GAD ++      ++G    N PLW+AL N   DIA  LV  G D   W         QTLLHR I E  E  A FLI  GCD  S      P    +N E      +G TPLH+A   GLE  V+ LL     +VN Q+A G T +H+A+  +H  V+  LL     ++L++RD QG TPF  AM   N K+A +IL+    AA+++DN GRNFLHVAVQ  + E+V FLI V+AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ LHIL    +EN   IF L L+  P +P+D+ DA G+T L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  +F +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC +CF+ L  G
Sbjct:  540 SVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVSRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPD----EKG----NPPLWLALANNLEDIASTLVRHGCDATCWGPG-PGGCLQTLLHRAIDENNEPTACFLIRSGCDVNS------PRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGA-NVNAQDAEGRTPIHVAISSQH-GVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1167

HSP 2 Score: 233.417 bits (594), Expect = 9.910e-62
Identity = 283/1106 (25.59%), Postives = 480/1106 (43.40%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKD-----FNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNA-----NRGLLMDLALGKKQNKEILKTT-----HRCKGRKVNSDKQL---TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQS--LLHLAVKKGNIEAVQFLIKIGCDINVRSINK----MTPLLLATEKSNIDIVRILCLSGADPNIT----SNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWS------IHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIS---TMENKNPSNSISNYESNNHYI---EGNTPLHMACQ-MGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAAR---SILQYHPQAADEIDNLGRNFLHVAV 3232
            L KH  LL+QEY K+  K    + +   L   +   S+ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ +E++L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A        A+ ++ +  I   L+Q GA+                 NM  +   RT L ++I++GNE V   +L   +C  ++        + K    S               LWLA+      +H+ +  D     F D V +    +F        LI+  +      D+ TGN ++      G E AA+F+  A N                     VN  N + E+  H A  + L NL   LLQ GA+PN+     +                       L K++     + + ++ QT                    P   +M I  +  H   +S+ + +K+NA     N  ++ D +L   +++ +L        H    + + S   +     D  T  H+A++ ++ K   LF+   +    V+   +   GE+   L + N L  V D I  R           D  V DE+    L LA+     +    L++ GCD             T L  A +++N      L  SG D N      +N   +E   +   PL +A +    +    L+E GA+V+         IH   + +  ++ + ++   +   N    +G    +   T +N   + +I   ES        +G   LH+A Q   +ESV+  +     ++  VQ+A+  T LHLAV+   E ++ +LL    K+N   +  Q      TA+ L+ Q+      S+L  +      +D  G N LH+AV
Sbjct:    9 LEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP----------------NMQ-DSKGRTPLHVSIMAGNEYVFSQLL---QCKQLD-------LELKDHEGST-------------ALWLAV------QHITVSSDQSVNPFED-VPVVNGTSFDENSFAARLIQRGSHTDA-PDTATGNCLLQRAAGAGNEAAALFL--ATNGAH------------------VNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALP----------------------LPKEAASLTSLADSVHLQT--------------------PL--HMAIAYN--HPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSA-LFLLEHQADINVSRTQD---GETALQLAIRNQLPLVVDAICTR---------GADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQ------TALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 981

HSP 3 Score: 66.6254 bits (161), Expect = 3.283e-10
Identity = 98/431 (22.74%), Postives = 174/431 (40.37%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNI-----------TSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNV-QNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNI------------RVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N R+    TPL  A      ++   L   GA+PN+            +++ S    + L  PL +A+     D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV +   G T+L LA++ +   V+  +       ++S+ D +G+ P   A+  + +  A +++++   A       G   +  LH A+   N     FLI+   ++N               +D    TPLHLA   G  E+ ++ L+  GAN+  +  E +  +H+A+  +   II  L+ +     + +D +  TP   A+   N    + +L   S   +  + KG N LH+   N
Sbjct:  476 FLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVSRTQDGETALQLAIRNQLPLVVDAICT--RGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDG--QTPLHLAASWGL-EETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQN 882

HSP 4 Score: 61.6178 bits (148), Expect = 1.081e-8
Identity = 117/462 (25.32%), Postives = 183/462 (39.61%), Query Frame = 2

Query: 2648 VALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK-------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            +AL+     IA  LV   ADVDM      D    +LLH+ I      AA FLI  G   +  +    + P + ++ Y S  H  +                         G TPLH++   G E V   LL   ++D+ +++  G T+L LAV+                 ++++   Q   PF        T+ +  N  AAR I +  H  A D     G   L  A    N  A  FL    A++N R K  +  TPLH A   G   +L   L+  GAN   +T E                    Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  +   G TAL L A+++   L V A+  +GA +   + +G
Sbjct:  262 LALSRRLESIATTLVSHKADVDM-----VDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQ-----------------HITVSSDQSVNPFEDVPVVNGTSFD-ENSFAARLIQRGSHTDAPDTAT--GNCLLQRAAGAGNEAAALFLATNGAHVNHRNK--WGETPLHTACRHGLA-NLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINV-SRTQDGETALQL-AIRNQLPLVVDAICTRGADMSVPDEKG 689

HSP 5 Score: 56.225 bits (134), Expect = 5.242e-7
Identity = 57/210 (27.14%), Postives = 90/210 (42.86%), Query Frame = 2

Query: 3011 LHLAVKF-RHEAVLTHLLNPKYKL--NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLA-VIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENIL 3628
            LH A+K  R + V  +L+    +L   L+  DH G      A+    +  A +++  H    D +D  G + LH  +Q  +  A  FLI+  A +N     A Q TPLHL  +  + +                        H A V+ E   I   LL+ GA+ + QD+K  TPLH+++  GN  +   LL      ++ K+ +G   L
Sbjct:  222 LHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVS-HKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGA-QETPLHLVALYSSKK------------------------HSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTAL 405

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493])

HSP 1 Score: 135.961 bits (341), Expect = 2.927e-31
Identity = 145/532 (27.26%), Postives = 233/532 (43.80%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIH---YKDNYEQTLL-----HRTILEMKE--------------QAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLL 3883
            + S +D       + LH+A   G  E V+ L+K G +IN +S N  TPL +A ++++ID+V+ L  +GA+     +  +++GF     PL VAL         IL+E      V + ++H    KD+ +   L     H   ++ K                 A  L++RG     T  N                  G TPLH+A + G  ++VK LL    +ID   ++  G T LH A +  H+ V+  LL  +    L  R   G +P H A +  + +  + +LQ H    D++       LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +    +   LL  GA+      +GFT     H++ ++    + KLL
Sbjct:   65 RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN----QSTATEDGF----TPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN------------------GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLL--ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ-HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL---HVAAKYGSLDVAKLL 553

HSP 2 Score: 114.775 bits (286), Expect = 8.443e-25
Identity = 133/538 (24.72%), Postives = 223/538 (41.45%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLG 3778
            T D  TP H A ++ + +++ L +           L     G SP  +      +     + +         + +D + +D  + LH+A   G+    + L+    + N R++N  TPL +A +K+ I ++ +L   GA    +   I++ G      P+ VA      +I  +L++ GA  D+ +I  +          T L M  +A    + R C     + N    ++ +  E         TPLH+A ++G   +V+ LL  +    +     G T LH++ +     V + LL      +L+ +  +G TP H A +  +   A+ +LQ    AAD     G   LH+A +    +    L+   A  NI  K     TPLHLA   G   D++  L+  GANI   T      LHLA   ++V +   L ++GA          TPL +A   GNV ++  LL   +      N K +N    L    ++    I +++L H  +   +   A GNTAL +       RLG
Sbjct:  267 TRDGLTPLHCAARSGHDQVVELLL-----ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQH-------KAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGA----SIQAITESGL----TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGE----------TALHMAARAGQVEVVR-C----LLRNGALVDARAREE--------QTPLHIASRLGKTEIVQ-LLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK--KGFTPLHVAAKYGSLDVAKLLLQRR-AAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGV--TPLHLASQEGH-TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANV----NAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK--PNATTANGNTALAIA-----KRLG 743

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Celegans
Match: F22G12.4 (pep chromosome:WBcel235:I:13155239:13159179:-1 gene:WBGene00009064.1 transcript:F22G12.4c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F22G12.4)

HSP 1 Score: 222.631 bits (566), Expect = 5.565e-60
Identity = 188/623 (30.18%), Postives = 297/623 (47.67%), Query Frame = 2

Query: 2405 DEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCP---------------------------LWVALNNCRFDIADILVEAGADVD------MWSIHYKDNYE-----QTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLL--SSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIR-VKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI--------LSNNCRENGIVIFSLIL----------DHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            D+++ L +AV+K ++++ +  IK G D+N R  N  T LL+    +N D + +  +           IS + ++E  C                            L  AL++ + D+A +LV  G DV+             D  E     QTLLHR I +  +Q+A FLI  G D  +  E +NP++       ++ +    TP HMA       V++ L   S+N  DV+   + G T  H+ V+ ++   +  LL+ +    + IRD  G T    AM + + + A  I+   P AA + +  G N LH A++  + E+V FL+ V      R + D    TPLHLA I+   E ++R+LIL   ++   + +    L  A+        + L+ENGA  + +D   E  +  AVR G++D I+ +  +S T   ++N  G   LHI        L      + ++   LI             +  F +D +DA GNTAL +   + N+ +  +LL + A +G  NN    +F  E  ++Q +L LL+SL +EP W DG+ C  C  +FS+ +RKHHCRHCGR VC KCS   MPI K+  +K VRVC+VC + +  G
Sbjct:  201 DDRTALDIAVEKRDLKSARICIKGGADVNARDANGQT-LLVKAILANDDEMGVFLIEHDAKAKNDERISSKTYVEAACERGLLNTVRSFISNGCKLNSRCSTGYSLLHSALSHQKLDVASLLVNFGCDVESRVALGAGGEVLDDGDESWITKQTLLHRLIDDGDQQSAVFLIESGADVNARKEYRNPTD-------DDQF----TPAHMAVSWAQNDVLRALRDHSANLCDVD---SDGRTPAHIGVREQNVDGVKILLDAENVEFIPIRDKFGQTILSQAMAMKDHQIASLIVARQPHAAVQTNGNGENLLHQAIRQNDIESVLFLLAVAKADPCRPITDGSLKTPLHLAAIA-KDEMILRNLILVNDDVNVTSADGTTPLLEALKARNDKHAAILMENGAEPNVKDEYGENAMLCAVRSGSLDCIRAVADSSRTNRYARNKIGYTSLHICALLTIDKLPKRTSSSDVIELVLIYAEEEAQAQNEKQFAGF-IDARDADGNTALMIAYSQGNAGVCRSLLKRRACMGQRNNGDVNVFTYETATKQLLLGLLESLEAEPRWSDGDTC-DCGARFSLTSRKHHCRHCGRHVCSKCSETTMPIAKYGEEKRVRVCDVCAHVISTG 805

HSP 2 Score: 58.151 bits (139), Expect = 4.828e-8
Identity = 78/324 (24.07%), Postives = 146/324 (45.06%), Query Frame = 2

Query: 2390 DKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVR-------SINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMAC-QMGLESVVKNLLSSNKIDV--NVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHL 3331
            D+  I +Q+LLH  +  G+ ++  FLI+ G D+N R         ++ TP  +A   +  D++R L     D +     +  +G      P  + +     D   IL++A    ++  I  +D + QT+L + +     Q A+ +++R            P  ++   ++N +   G   LH A  Q  +ESV+  LL+  K D    + + +  T LHLA   + E +L +L+     +N++  D  G TP   A++  N K A +IL  +    +  D  G N +  AV++ + + +  +   ++  N   ++   YT LH+
Sbjct:  345 DESWITKQTLLHRLIDDGDQQSAVFLIESGADVNARKEYRNPTDDDQFTPAHMAVSWAQNDVLRAL----RDHSANLCDVDSDG----RTPAHIGVREQNVDGVKILLDA---ENVEFIPIRDKFGQTILSQAMAMKDHQIASLIVAR-----------QPHAAV---QTNGN---GENLLHQAIRQNDIESVLF-LLAVAKADPCRPITDGSLKTPLHLAAIAKDEMILRNLILVNDDVNVTSAD--GTTPLLEALKARNDKHA-AILMENGAEPNVKDEYGENAMLCAVRSGSLDCIRAVAD-SSRTNRYARNKIGYTSLHI 635

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Celegans
Match: F22G12.4 (pep chromosome:WBcel235:I:13155239:13159874:-1 gene:WBGene00009064.1 transcript:F22G12.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F22G12.4)

HSP 1 Score: 222.631 bits (566), Expect = 1.592e-59
Identity = 188/623 (30.18%), Postives = 297/623 (47.67%), Query Frame = 2

Query: 2405 DEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCP---------------------------LWVALNNCRFDIADILVEAGADVD------MWSIHYKDNYE-----QTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLL--SSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIR-VKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI--------LSNNCRENGIVIFSLIL----------DHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            D+++ L +AV+K ++++ +  IK G D+N R  N  T LL+    +N D + +  +           IS + ++E  C                            L  AL++ + D+A +LV  G DV+             D  E     QTLLHR I +  +Q+A FLI  G D  +  E +NP++       ++ +    TP HMA       V++ L   S+N  DV+   + G T  H+ V+ ++   +  LL+ +    + IRD  G T    AM + + + A  I+   P AA + +  G N LH A++  + E+V FL+ V      R + D    TPLHLA I+   E ++R+LIL   ++   + +    L  A+        + L+ENGA  + +D   E  +  AVR G++D I+ +  +S T   ++N  G   LHI        L      + ++   LI             +  F +D +DA GNTAL +   + N+ +  +LL + A +G  NN    +F  E  ++Q +L LL+SL +EP W DG+ C  C  +FS+ +RKHHCRHCGR VC KCS   MPI K+  +K VRVC+VC + +  G
Sbjct:  294 DDRTALDIAVEKRDLKSARICIKGGADVNARDANGQT-LLVKAILANDDEMGVFLIEHDAKAKNDERISSKTYVEAACERGLLNTVRSFISNGCKLNSRCSTGYSLLHSALSHQKLDVASLLVNFGCDVESRVALGAGGEVLDDGDESWITKQTLLHRLIDDGDQQSAVFLIESGADVNARKEYRNPTD-------DDQF----TPAHMAVSWAQNDVLRALRDHSANLCDVD---SDGRTPAHIGVREQNVDGVKILLDAENVEFIPIRDKFGQTILSQAMAMKDHQIASLIVARQPHAAVQTNGNGENLLHQAIRQNDIESVLFLLAVAKADPCRPITDGSLKTPLHLAAIA-KDEMILRNLILVNDDVNVTSADGTTPLLEALKARNDKHAAILMENGAEPNVKDEYGENAMLCAVRSGSLDCIRAVADSSRTNRYARNKIGYTSLHICALLTIDKLPKRTSSSDVIELVLIYAEEEAQAQNEKQFAGF-IDARDADGNTALMIAYSQGNAGVCRSLLKRRACMGQRNNGDVNVFTYETATKQLLLGLLESLEAEPRWSDGDTC-DCGARFSLTSRKHHCRHCGRHVCSKCSETTMPIAKYGEEKRVRVCDVCAHVISTG 898

HSP 2 Score: 57.7658 bits (138), Expect = 5.521e-8
Identity = 78/324 (24.07%), Postives = 146/324 (45.06%), Query Frame = 2

Query: 2390 DKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVR-------SINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMAC-QMGLESVVKNLLSSNKIDV--NVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHL 3331
            D+  I +Q+LLH  +  G+ ++  FLI+ G D+N R         ++ TP  +A   +  D++R L     D +     +  +G      P  + +     D   IL++A    ++  I  +D + QT+L + +     Q A+ +++R            P  ++   ++N +   G   LH A  Q  +ESV+  LL+  K D    + + +  T LHLA   + E +L +L+     +N++  D  G TP   A++  N K A +IL  +    +  D  G N +  AV++ + + +  +   ++  N   ++   YT LH+
Sbjct:  438 DESWITKQTLLHRLIDDGDQQSAVFLIESGADVNARKEYRNPTDDDQFTPAHMAVSWAQNDVLRAL----RDHSANLCDVDSDG----RTPAHIGVREQNVDGVKILLDA---ENVEFIPIRDKFGQTILSQAMAMKDHQIASLIVAR-----------QPHAAV---QTNGN---GENLLHQAIRQNDIESVL-FLLAVAKADPCRPITDGSLKTPLHLAAIAKDEMILRNLILVNDDVNVTSAD--GTTPLLEALKARNDKHA-AILMENGAEPNVKDEYGENAMLCAVRSGSLDCIRAVAD-SSRTNRYARNKIGYTSLHI 728

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Celegans
Match: F22G12.4 (pep chromosome:WBcel235:I:13155239:13161508:-1 gene:WBGene00009064.1 transcript:F22G12.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F22G12.4)

HSP 1 Score: 223.016 bits (567), Expect = 5.537e-59
Identity = 188/623 (30.18%), Postives = 297/623 (47.67%), Query Frame = 2

Query: 2405 DEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCP---------------------------LWVALNNCRFDIADILVEAGADVD------MWSIHYKDNYE-----QTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLL--SSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIR-VKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI--------LSNNCRENGIVIFSLIL----------DHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            D+++ L +AV+K ++++ +  IK G D+N R  N  T LL+    +N D + +  +           IS + ++E  C                            L  AL++ + D+A +LV  G DV+             D  E     QTLLHR I +  +Q+A FLI  G D  +  E +NP++       ++ +    TP HMA       V++ L   S+N  DV+   + G T  H+ V+ ++   +  LL+ +    + IRD  G T    AM + + + A  I+   P AA + +  G N LH A++  + E+V FL+ V      R + D    TPLHLA I+   E ++R+LIL   ++   + +    L  A+        + L+ENGA  + +D   E  +  AVR G++D I+ +  +S T   ++N  G   LHI        L      + ++   LI             +  F +D +DA GNTAL +   + N+ +  +LL + A +G  NN    +F  E  ++Q +L LL+SL +EP W DG+ C  C  +FS+ +RKHHCRHCGR VC KCS   MPI K+  +K VRVC+VC + +  G
Sbjct:  498 DDRTALDIAVEKRDLKSARICIKGGADVNARDANGQT-LLVKAILANDDEMGVFLIEHDAKAKNDERISSKTYVEAACERGLLNTVRSFISNGCKLNSRCSTGYSLLHSALSHQKLDVASLLVNFGCDVESRVALGAGGEVLDDGDESWITKQTLLHRLIDDGDQQSAVFLIESGADVNARKEYRNPTD-------DDQF----TPAHMAVSWAQNDVLRALRDHSANLCDVD---SDGRTPAHIGVREQNVDGVKILLDAENVEFIPIRDKFGQTILSQAMAMKDHQIASLIVARQPHAAVQTNGNGENLLHQAIRQNDIESVLFLLAVAKADPCRPITDGSLKTPLHLAAIA-KDEMILRNLILVNDDVNVTSADGTTPLLEALKARNDKHAAILMENGAEPNVKDEYGENAMLCAVRSGSLDCIRAVADSSRTNRYARNKIGYTSLHICALLTIDKLPKRTSSSDVIELVLIYAEEEAQAQNEKQFAGF-IDARDADGNTALMIAYSQGNAGVCRSLLKRRACMGQRNNGDVNVFTYETATKQLLLGLLESLEAEPRWSDGDTC-DCGARFSLTSRKHHCRHCGRHVCSKCSETTMPIAKYGEEKRVRVCDVCAHVISTG 1102

HSP 2 Score: 110.153 bits (274), Expect = 6.511e-24
Identity = 86/344 (25.00%), Postives = 170/344 (49.42%), Query Frame = 2

Query:   62 ETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKST---IPGHRIIFEANGCEW---NGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSS---KKVELCETLLKSCANLNSVD-NYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTP----IQLLANLIPS 1051
            E  + + ++L+++++ + +++  L+ KY+    L  + ST D+F   L  +  SL +  +FSD++ K   ++   +P H+ +  A    W   NG D    E    ++ +       ++WIY  E++     E L K+ + A    L+ LKN C     +++  DNCI  Y+ A + S+  L +   ++I   W +  PA F  + A++   L++  +   LH  V   R+DV+FLY  +N +++ +++N +       L++AL S   K  ++   L++  A++N  D   G ++L +  ++++  +  FL+ NG          SQ+P    +  +A+ IPS
Sbjct:    6 EPKIDYLDILKEQFNALQSEHLELRRKYE----LECSSSTPDSFPSRLLSLTSSLLEKPRFSDVTFKFAGNSLKSVPAHKYVLAARTDFWKFENGGD-EKSEIQISDDVDFEAFHVAIRWIYTDEIDLKMEDEKLLKVCETATSFRLEQLKNVCVQQLGARLHVDNCIKIYEFAEKQSLRQLSTVAGSMIAGAWPKLGPAHFAQMTAALLYRLIDGNTKNVLHSIVSIGREDVLFLYFMQNSAKIPKILNDLDPQGASALEIALCSEHEKSRQIAAQLVEKGADVNVKDAERGETILMRMCRKENLSAMDFLLGNGADGRD-----SQSPGDYNVVHVASRIPS 339

HSP 3 Score: 58.151 bits (139), Expect = 5.001e-8
Identity = 78/324 (24.07%), Postives = 146/324 (45.06%), Query Frame = 2

Query: 2390 DKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVR-------SINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMAC-QMGLESVVKNLLSSNKIDV--NVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHL 3331
            D+  I +Q+LLH  +  G+ ++  FLI+ G D+N R         ++ TP  +A   +  D++R L     D +     +  +G      P  + +     D   IL++A    ++  I  +D + QT+L + +     Q A+ +++R            P  ++   ++N +   G   LH A  Q  +ESV+  LL+  K D    + + +  T LHLA   + E +L +L+     +N++  D  G TP   A++  N K A +IL  +    +  D  G N +  AV++ + + +  +   ++  N   ++   YT LH+
Sbjct:  642 DESWITKQTLLHRLIDDGDQQSAVFLIESGADVNARKEYRNPTDDDQFTPAHMAVSWAQNDVLRAL----RDHSANLCDVDSDG----RTPAHIGVREQNVDGVKILLDAE---NVEFIPIRDKFGQTILSQAMAMKDHQIASLIVAR-----------QPHAAV---QTNGN---GENLLHQAIRQNDIESVL-FLLAVAKADPCRPITDGSLKTPLHLAAIAKDEMILRNLILVNDDVNVTSAD--GTTPLLEALKARNDKHA-AILMENGAEPNVKDEYGENAMLCAVRSGSLDCIRAVAD-SSRTNRYARNKIGYTSLHI 932

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 122.865 bits (307), Expect = 1.290e-27
Identity = 125/485 (25.77%), Postives = 214/485 (44.12%), Query Frame = 2

Query: 2162 LTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCD-TISTMENKNPSNSISNY-----------ESNNHYIEGN---TPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPL 3571
            +T+D  TP H+A    ++++  L +  D   +  +  +N   G +P  +      I    K+ E L+K     + I+       + LH+A   G I  V +L++ G + +V ++   TPL LA   +  D+VR+L  +GA  +  +         EL  PL +A      DI  +L++AGA+ +  +   +DNY    LH    E +E+ A  L+    D T+ T +   P +  S Y                 IEG    TPLH+A     + V   LL  N          G T LH+A K     + + LL  ++K + + +   G TP H + +  +++ +  +++       + +N G   +H+  Q  +      L    A +N +      YTPLH+A   G   ++++ L+  GA++  +T      LH A        + +LLENGAS + Q    +TPL +A R G V +++ L
Sbjct:  355 VTVDYLTPLHVAAHCGHVRVAKLLL--DRSADPNSRALN---GFTPLHIACKKNRI----KVVELLLKY---RAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQAR--------ELQTPLHIASRLGNTDIVILLLQAGANSNATT---RDNYSP--LHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAM-LLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLL--QFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANN-GLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAG--YTPLHVACHFGQL-NMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807

HSP 2 Score: 120.168 bits (300), Expect = 1.007e-26
Identity = 142/599 (23.71%), Postives = 248/599 (41.40%), Query Frame = 2

Query: 2342 KIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSN---------SISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ-------------------------------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLL---ANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPE-------------------------------FPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF-ILKLLDSLSSEPN 3907
            ++   LIK   + +++D       + LH+A   G    V  L++ G ++NV+S+N  TPL +A ++++ ++V+ L   GA+  ++    +++GF     PL VAL      +  +L+E  +   V + ++H     + T    T+L   E   +     G   +    +    N         +  NY++ ++     +PLH+A + G  ++   LLS   I ++ +     T LH A +  H+ V+  L+       +S +   G  P H A +  +  AAR++L YH    D++       LHVA    +      L+  +A+ N R  + F                                 TPLH+A   GA  +++  L+  GAN   ET+  +  LHLA    +  ++  L+ NGA    Q  +++TPLH+A R GN D++  LL   ANS+ T +       + LHI +   +E    +  ++LDH  +                                PVD +     T L + A  +N ++ + LL  GAS       G+T  +      Q  I   L    ++PN
Sbjct:   80 EVVRELIK---RQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALS----TEDGFT----PLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTA-ATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNI----SPLHVATKWGRTNMANLLLSRGAI-IDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAP--ISAKTKNGLAPLHMAAQGDHVDAARTLL-YHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAI-NIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDN----YSPLHIAAKEGQEE---VAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPN 650

HSP 3 Score: 112.079 bits (279), Expect = 2.398e-24
Identity = 132/502 (26.29%), Postives = 218/502 (43.43%), Query Frame = 2

Query: 2387 IDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGAD-PNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA-ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT-LFNSEHISEQFILKLL 3883
            ID    D  + LH A + G+ + V  L+  G  I+ ++ N + PL +A +  ++D  R L    A   ++T + ++         PL VA +     +A +L++  AD +  +++       T LH    + + +    L+       +T E+                  G TPLH+A  MG  ++V  LL     + +V+   G T LHLA +     V+  L+    K++   R+ Q  TP H A  L N      +LQ    + A   DN     LH+A +    E    L+  NA+  +  K  F  TPLHLA   G  E ++R L+  G  +  E   +   LH+A  +    +   LLENGAS         TPLH+A +   +++   LL   +    +K+  G   LH+   + +E    I  L++++  +  V  K   G TA+ LCA +D+  +   L   GA +    N G+T L  + H  +  ++K L
Sbjct:  286 IDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLT---------PLHVAAHCGHVRVAKLLLDRSADPNSRALN-----GFTPLHIACKKNRIKVVELLLKYRAAIEATTES------------------GLTPLHVAAFMGAINIVIYLLQQGA-NPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQ--TPLHIASRLGNTDIVILLLQAGANSNATTRDNYSP--LHIAAKEGQEEVAGILLDHNADKTLLTKKGF--TPLHLASKYGNLE-VVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADP-NAKSRAGFTPLHL---SAQEGHKEISGLLIENGSD--VGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFL 741

HSP 4 Score: 102.449 bits (254), Expect = 2.425e-21
Identity = 123/463 (26.57%), Postives = 201/463 (43.41%), Query Frame = 2

Query: 2429 AVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQ----YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGAS 3805
            A + G++E V  L++ G DIN  + N +  L LA+++ + ++VR L    A  +      +++G    N  L +A    +  I  ILVE GA+V++ S++       T L+    E  E+   +L+  G +   + E                  +G TPL +A Q G + VV  LL ++      +      +LH+A K       T LL  ++  N  +    G TP H A    ++   + +L+     + QA   I       LHVA +         L+   A ++ R KD    TPLH A  SG  + ++  L++ GA I+ +T      LH+A   + V     LL + A          TPLH+A   G+V + K LL + S    S+ L G   LHI    C++N I +  L+L +     ++     G T L + A      + + LL +GA+
Sbjct:   40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAA----TRKG----NTALHIASLAGQSLIVTILVENGANVNVQSVN-----GFTPLYMAAQENHEEVVKYLLKHGANQALSTE------------------DGFTPLAVALQQGHDRVVAVLLENDS-----KGKVRLPALHIAAKKDDTTAATLLLQNEH--NPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISP-----LHVATKWGRTNMANLLLSRGAIIDSRTKDLL--TPLHCAARSGH-DQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAK-LLLDRSADPNSRALNGFTPLHIA---CKKNRIKVVELLLKY--RAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGAN 450

HSP 5 Score: 59.6918 bits (143), Expect = 2.071e-8
Identity = 73/292 (25.00%), Postives = 119/292 (40.75%), Query Frame = 2

Query: 2147 NSDKQL-TIDLCTPTHLAVKTKNIKIINLFIFHD-----EGRNKVNWL--MNDYAGESPFTLCLWNGL------------ISVCDKIFERLIKTDFKTSEIDKIVIDEQSL--LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNL 2956
            N+DK L T    TP HLA K  N++++ L +        EG+N+V  L     Y  +    L L NG             + +  K  +  I +     + D           LHL+ ++G+ E    LI+ G D+  ++ N +T + L  ++ ++ + +IL  +GA+ N  +N     G+     PL VA +  + ++   LVE GADV       K     T LH+   +       +L+  G                     N     G TPL +A ++G  SVV+ L
Sbjct:  547 NADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTN----AGYT----PLHVACHFGQLNMVKFLVENGADVGE-----KTRASYTPLHQAAQQGHNNCVRYLLENGA------------------SPNEQTATGQTPLSIAQRLGYVSVVETL 807

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Query: 2162 LTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCD-TISTMENKNPSNSISNY-----------ESNNHYIEGN---TPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPL 3571
            +T+D  TP H+A    ++++  L +  D   +  +  +N   G +P  +      I    K+ E L+K     + I+       + LH+A   G I  V +L++ G + +V ++   TPL LA   +  D+VR+L  +GA  +  +         EL  PL +A      DI  +L++AGA+ +  +   +DNY    LH    E +E+ A  L+    D T+ T +   P +  S Y                 IEG    TPLH+A     + V   LL  N          G T LH+A K     + + LL  ++K + + +   G TP H + +  +++ +  +++       + +N G   +H+  Q  +      L    A +N +      YTPLH+A   G   ++++ L+  GA++  +T      LH A        + +LLENGAS + Q    +TPL +A R G V +++ L
Sbjct:  355 VTVDYLTPLHVAAHCGHVRVAKLLL--DRSADPNSRALN---GFTPLHIACKKNRI----KVVELLLKY---RAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQAR--------ELQTPLHIASRLGNTDIVILLLQAGANSNATT---RDNYSP--LHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAM-LLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLL--QFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANN-GLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAG--YTPLHVACHFGQL-NMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807

HSP 2 Score: 120.168 bits (300), Expect = 1.007e-26
Identity = 142/599 (23.71%), Postives = 248/599 (41.40%), Query Frame = 2

Query: 2342 KIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSN---------SISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ-------------------------------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLL---ANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPE-------------------------------FPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF-ILKLLDSLSSEPN 3907
            ++   LIK   + +++D       + LH+A   G    V  L++ G ++NV+S+N  TPL +A ++++ ++V+ L   GA+  ++    +++GF     PL VAL      +  +L+E  +   V + ++H     + T    T+L   E   +     G   +    +    N         +  NY++ ++     +PLH+A + G  ++   LLS   I ++ +     T LH A +  H+ V+  L+       +S +   G  P H A +  +  AAR++L YH    D++       LHVA    +      L+  +A+ N R  + F                                 TPLH+A   GA  +++  L+  GAN   ET+  +  LHLA    +  ++  L+ NGA    Q  +++TPLH+A R GN D++  LL   ANS+ T +       + LHI +   +E    +  ++LDH  +                                PVD +     T L + A  +N ++ + LL  GAS       G+T  +      Q  I   L    ++PN
Sbjct:   80 EVVRELIK---RQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALS----TEDGFT----PLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTA-ATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNI----SPLHVATKWGRTNMANLLLSRGAI-IDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAP--ISAKTKNGLAPLHMAAQGDHVDAARTLL-YHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAI-NIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDN----YSPLHIAAKEGQEE---VAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPN 650

HSP 3 Score: 112.079 bits (279), Expect = 2.398e-24
Identity = 132/502 (26.29%), Postives = 218/502 (43.43%), Query Frame = 2

Query: 2387 IDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGAD-PNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA-ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT-LFNSEHISEQFILKLL 3883
            ID    D  + LH A + G+ + V  L+  G  I+ ++ N + PL +A +  ++D  R L    A   ++T + ++         PL VA +     +A +L++  AD +  +++       T LH    + + +    L+       +T E+                  G TPLH+A  MG  ++V  LL     + +V+   G T LHLA +     V+  L+    K++   R+ Q  TP H A  L N      +LQ    + A   DN     LH+A +    E    L+  NA+  +  K  F  TPLHLA   G  E ++R L+  G  +  E   +   LH+A  +    +   LLENGAS         TPLH+A +   +++   LL   +    +K+  G   LH+   + +E    I  L++++  +  V  K   G TA+ LCA +D+  +   L   GA +    N G+T L  + H  +  ++K L
Sbjct:  286 IDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLT---------PLHVAAHCGHVRVAKLLLDRSADPNSRALN-----GFTPLHIACKKNRIKVVELLLKYRAAIEATTES------------------GLTPLHVAAFMGAINIVIYLLQQGA-NPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQ--TPLHIASRLGNTDIVILLLQAGANSNATTRDNYSP--LHIAAKEGQEEVAGILLDHNADKTLLTKKGF--TPLHLASKYGNLE-VVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADP-NAKSRAGFTPLHL---SAQEGHKEISGLLIENGSD--VGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFL 741

HSP 4 Score: 102.449 bits (254), Expect = 2.425e-21
Identity = 123/463 (26.57%), Postives = 201/463 (43.41%), Query Frame = 2

Query: 2429 AVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQ----YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGAS 3805
            A + G++E V  L++ G DIN  + N +  L LA+++ + ++VR L    A  +      +++G    N  L +A    +  I  ILVE GA+V++ S++       T L+    E  E+   +L+  G +   + E                  +G TPL +A Q G + VV  LL ++      +      +LH+A K       T LL  ++  N  +    G TP H A    ++   + +L+     + QA   I       LHVA +         L+   A ++ R KD    TPLH A  SG  + ++  L++ GA I+ +T      LH+A   + V     LL + A          TPLH+A   G+V + K LL + S    S+ L G   LHI    C++N I +  L+L +     ++     G T L + A      + + LL +GA+
Sbjct:   40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAA----TRKG----NTALHIASLAGQSLIVTILVENGANVNVQSVN-----GFTPLYMAAQENHEEVVKYLLKHGANQALSTE------------------DGFTPLAVALQQGHDRVVAVLLENDS-----KGKVRLPALHIAAKKDDTTAATLLLQNEH--NPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISP-----LHVATKWGRTNMANLLLSRGAIIDSRTKDLL--TPLHCAARSGH-DQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAK-LLLDRSADPNSRALNGFTPLHIA---CKKNRIKVVELLLKY--RAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGAN 450

HSP 5 Score: 59.6918 bits (143), Expect = 2.071e-8
Identity = 73/292 (25.00%), Postives = 119/292 (40.75%), Query Frame = 2

Query: 2147 NSDKQL-TIDLCTPTHLAVKTKNIKIINLFIFHD-----EGRNKVNWL--MNDYAGESPFTLCLWNGL------------ISVCDKIFERLIKTDFKTSEIDKIVIDEQSL--LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNL 2956
            N+DK L T    TP HLA K  N++++ L +        EG+N+V  L     Y  +    L L NG             + +  K  +  I +     + D           LHL+ ++G+ E    LI+ G D+  ++ N +T + L  ++ ++ + +IL  +GA+ N  +N     G+     PL VA +  + ++   LVE GADV       K     T LH+   +       +L+  G                     N     G TPL +A ++G  SVV+ L
Sbjct:  547 NADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTN----AGYT----PLHVACHFGQLNMVKFLVENGADVGE-----KTRASYTPLHQAAQQGHNNCVRYLLENGA------------------SPNEQTATGQTPLSIAQRLGYVSVVETL 807

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Fly
Match: CG41099 (gene:FBgn0039955 transcript:FBtr0113991)

HSP 1 Score: 345.125 bits (884), Expect = 2.694e-99
Identity = 224/652 (34.36%), Postives = 341/652 (52.30%), Query Frame = 2

Query: 2156 KQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-NPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCR----ENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            K +   L +  H+AV+   I  +  F+      + +++   D  G+SP +LCL     ++   +           S+++    +  S LH ++K  + +   FL++ G DI   + N  + L L+ +    ++V  LC  G   +I  N  S         PLW AL     D+A ILV  G D D W     +   QTLLHR I E KE  A FLI   CD  S+   + P     N E  +   +  +PLH+ C  G   V++ L+     +VN+ +A   + LH+A++ +++ +++ LL +P   ++L +RD  G+TPF TA++  N  AA+ IL   P AA+++D  GRNFLH+A+   + E+V FL+ +  ++N RV DA Q +PLHLA  S   E + R+LILAGA +      ++  LH+A+    +  +S L++N A     D      LH+AVR     +++ LL  S    ++ NLKG N LH L   CR        +I  L L+  P++P++  D  GNT L L  ++  S L   L+  GA LG  N +G  +FN +  ++Q +  LLD L  E  W + + C  C  +F+I  RKHHCRHCGR++C KCS N++PI+KF I KPVRVC VCFN L  G
Sbjct:  485 KHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIR-------GGSDVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGES---------PLWSALEKGYEDVAKILVRHGIDTDCWD-EGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSS---RQPG---PNGEGGDEAQDKASPLHLCCHWGQTKVLQTLIDHGA-NVNLIDAESKSPLHVAIESQYDEIISILLCHPD--IDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFLLAIQVDVNSRVHDANQSSPLHLAAAS-QNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDATDADGNNALHIAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHEL---CRVVEDSTAGLICELFLESMPKYPINIPDMDGNTPLLLSFMRGQSPLCKILVKAGACLGTENKDGINIFNFKLATDQLLHNLLDQLPQESPWAESDYCQHCTNRFTITMRKHHCRHCGRVLCSKCSCNDVPILKFGINKPVRVCTVCFNVLQCG 1106

HSP 2 Score: 155.606 bits (392), Expect = 8.728e-38
Identity = 101/319 (31.66%), Postives = 169/319 (52.98%), Query Frame = 2

Query:   98 EYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNK-IVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLK-SCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIP 1048
            EY K+   Y  L+ KY+  I  S N  +  + +++     V SL+    ++DI I+ Q    P H+I+  A   +W    LSN ++++  +  +++   +++WIY  +L D QN  +   L+K AH   L  L   CE   ++ V   +CI FY  A E     L  +CS++I  +W++    DF  +   +  ++L+ ++ +PLH AV+  R+DVV L I + Y     LVN  SE+  L L++ALSSK  ++ ++L+    AN+N+V+  G+SLL  A++  D FS  FL+   C L+  S   S T + ++ N  P
Sbjct:   11 EYTKLQRCYVELQRKYNENIASSENEESGLSSFLSRLSLTVASLFDKNTYADIYIRSQTRVFPAHKIVLHARSEKWGNDLLSNIQQLDWSDLNEDVVLSLLRWIY-TDLIDLQNDGLALDLLKAAHRFGLPSLLGICERALVTSVGVRSCIRFYCVAEEVGASTLLEYCSSIISTHWDDLTTDDFQHMSGPLLFEMLKTKTKHPLHAAVRLLREDVVSLCI-QKYGN--SLVNTFSENGILPLEMALSSKNAKIAKSLVDNGMANINAVNMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKPSSDTALHIICNYGP 325

HSP 3 Score: 62.3882 bits (150), Expect = 3.258e-9
Identity = 146/649 (22.50%), Postives = 246/649 (37.90%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGN------IEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQ------------------------------TLLHRTILEMKEQAANFLISRG---------CDTISTMENKNPSNSISNYES-------------NNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-----------NPKYKLNLSIR-------------------DHQGHTPFHTAMELSNQKAARSILQYHPQAADEID----NLGRNFLHVAVQTMNREAVYFLIQVNANL--------NIRVKDAFQ--YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLL-ENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILH--ILSNNCRENGIVIFSLILDHYPEFPVDEK--DACGNTALFLCALKDNSRLGVALLLKGASL 3808
            P  +A+ +KN KI    +  D G   +N +  +  G S     L NG     + + ++    D  +           + LH+    G       +E V+ +++   +IN+++I   TPL +A  + N+++V++L      PNI  N+ + +    L   L +++ +  F IA IL+  GA  D  +    D+  Q                              T LH   L         LI  G         C   S +     +N+I   E+             N   I G++PL +   +   ++V  L+     DVN +N    + LH ++K     +   LL           N    L+LSI+                   +  G +P  +A+E   +  A+ IL  H    D  D       +  LH A+         FLIQ   +L        N    D  Q   +PLHL    G  + ++++LI  GAN+     E ++ LH+A+  +   IIS LL         +D    TP   A+   N +  + +L    T  +  +++G N LH  IL ++      V+F L +    +  V+ +  DA  ++ L L A   N  +   L+L GA +
Sbjct:  248 PLEMALSSKNAKIAKSLV--DNGMANINAV--NMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKP------SSDTALHIICNYGPDNTPEIMEVVKKILQRQLNINIQNIKGETPLHIAIARRNVEMVKLLL---KVPNIDINLRTYDEKCALE--LSLSMGDHEFLIASILLSMGARTDRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLTALHIAALNNMPNLVKKLIVNGASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIRGGS-DVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGESPLWSALEKGYEDVAK-ILVRHGIDTDCWDEGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSSRQPGPNGEGGDEAQDKASPLHLCCHWGQTK-VLQTLIDHGANVNLIDAESKSPLHVAIESQYDEIISILLCHPDIDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLES---VLFLLAI----QVDVNSRVHDANQSSPLHLAAASQNEMITRNLILAGARM 871

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Fly
Match: CG41099 (gene:FBgn0039955 transcript:FBtr0344573)

HSP 1 Score: 345.125 bits (884), Expect = 2.694e-99
Identity = 224/652 (34.36%), Postives = 341/652 (52.30%), Query Frame = 2

Query: 2156 KQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-NPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCR----ENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            K +   L +  H+AV+   I  +  F+      + +++   D  G+SP +LCL     ++   +           S+++    +  S LH ++K  + +   FL++ G DI   + N  + L L+ +    ++V  LC  G   +I  N  S         PLW AL     D+A ILV  G D D W     +   QTLLHR I E KE  A FLI   CD  S+   + P     N E  +   +  +PLH+ C  G   V++ L+     +VN+ +A   + LH+A++ +++ +++ LL +P   ++L +RD  G+TPF TA++  N  AA+ IL   P AA+++D  GRNFLH+A+   + E+V FL+ +  ++N RV DA Q +PLHLA  S   E + R+LILAGA +      ++  LH+A+    +  +S L++N A     D      LH+AVR     +++ LL  S    ++ NLKG N LH L   CR        +I  L L+  P++P++  D  GNT L L  ++  S L   L+  GA LG  N +G  +FN +  ++Q +  LLD L  E  W + + C  C  +F+I  RKHHCRHCGR++C KCS N++PI+KF I KPVRVC VCFN L  G
Sbjct:  485 KHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIR-------GGSDVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGES---------PLWSALEKGYEDVAKILVRHGIDTDCWD-EGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSS---RQPG---PNGEGGDEAQDKASPLHLCCHWGQTKVLQTLIDHGA-NVNLIDAESKSPLHVAIESQYDEIISILLCHPD--IDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFLLAIQVDVNSRVHDANQSSPLHLAAAS-QNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDATDADGNNALHIAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHEL---CRVVEDSTAGLICELFLESMPKYPINIPDMDGNTPLLLSFMRGQSPLCKILVKAGACLGTENKDGINIFNFKLATDQLLHNLLDQLPQESPWAESDYCQHCTNRFTITMRKHHCRHCGRVLCSKCSCNDVPILKFGINKPVRVCTVCFNVLQCG 1106

HSP 2 Score: 155.606 bits (392), Expect = 8.728e-38
Identity = 101/319 (31.66%), Postives = 169/319 (52.98%), Query Frame = 2

Query:   98 EYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNK-IVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLK-SCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIP 1048
            EY K+   Y  L+ KY+  I  S N  +  + +++     V SL+    ++DI I+ Q    P H+I+  A   +W    LSN ++++  +  +++   +++WIY  +L D QN  +   L+K AH   L  L   CE   ++ V   +CI FY  A E     L  +CS++I  +W++    DF  +   +  ++L+ ++ +PLH AV+  R+DVV L I + Y     LVN  SE+  L L++ALSSK  ++ ++L+    AN+N+V+  G+SLL  A++  D FS  FL+   C L+  S   S T + ++ N  P
Sbjct:   11 EYTKLQRCYVELQRKYNENIASSENEESGLSSFLSRLSLTVASLFDKNTYADIYIRSQTRVFPAHKIVLHARSEKWGNDLLSNIQQLDWSDLNEDVVLSLLRWIY-TDLIDLQNDGLALDLLKAAHRFGLPSLLGICERALVTSVGVRSCIRFYCVAEEVGASTLLEYCSSIISTHWDDLTTDDFQHMSGPLLFEMLKTKTKHPLHAAVRLLREDVVSLCI-QKYGN--SLVNTFSENGILPLEMALSSKNAKIAKSLVDNGMANINAVNMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKPSSDTALHIICNYGP 325

HSP 3 Score: 62.3882 bits (150), Expect = 3.258e-9
Identity = 146/649 (22.50%), Postives = 246/649 (37.90%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGN------IEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQ------------------------------TLLHRTILEMKEQAANFLISRG---------CDTISTMENKNPSNSISNYES-------------NNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-----------NPKYKLNLSIR-------------------DHQGHTPFHTAMELSNQKAARSILQYHPQAADEID----NLGRNFLHVAVQTMNREAVYFLIQVNANL--------NIRVKDAFQ--YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLL-ENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILH--ILSNNCRENGIVIFSLILDHYPEFPVDEK--DACGNTALFLCALKDNSRLGVALLLKGASL 3808
            P  +A+ +KN KI    +  D G   +N +  +  G S     L NG     + + ++    D  +           + LH+    G       +E V+ +++   +IN+++I   TPL +A  + N+++V++L      PNI  N+ + +    L   L +++ +  F IA IL+  GA  D  +    D+  Q                              T LH   L         LI  G         C   S +     +N+I   E+             N   I G++PL +   +   ++V  L+     DVN +N    + LH ++K     +   LL           N    L+LSI+                   +  G +P  +A+E   +  A+ IL  H    D  D       +  LH A+         FLIQ   +L        N    D  Q   +PLHL    G  + ++++LI  GAN+     E ++ LH+A+  +   IIS LL         +D    TP   A+   N +  + +L    T  +  +++G N LH  IL ++      V+F L +    +  V+ +  DA  ++ L L A   N  +   L+L GA +
Sbjct:  248 PLEMALSSKNAKIAKSLV--DNGMANINAV--NMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKP------SSDTALHIICNYGPDNTPEIMEVVKKILQRQLNINIQNIKGETPLHIAIARRNVEMVKLLL---KVPNIDINLRTYDEKCALE--LSLSMGDHEFLIASILLSMGARTDRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLTALHIAALNNMPNLVKKLIVNGASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIRGGS-DVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGESPLWSALEKGYEDVAK-ILVRHGIDTDCWDEGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSSRQPGPNGEGGDEAQDKASPLHLCCHWGQTK-VLQTLIDHGANVNLIDAESKSPLHVAIESQYDEIISILLCHPDIDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLES---VLFLLAI----QVDVNSRVHDANQSSPLHLAAASQNEMITRNLILAGARM 871

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Fly
Match: CG41099 (gene:FBgn0039955 transcript:FBtr0113989)

HSP 1 Score: 345.125 bits (884), Expect = 3.101e-99
Identity = 224/652 (34.36%), Postives = 341/652 (52.30%), Query Frame = 2

Query: 2156 KQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-NPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCR----ENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            K +   L +  H+AV+   I  +  F+      + +++   D  G+SP +LCL     ++   +           S+++    +  S LH ++K  + +   FL++ G DI   + N  + L L+ +    ++V  LC  G   +I  N  S         PLW AL     D+A ILV  G D D W     +   QTLLHR I E KE  A FLI   CD  S+   + P     N E  +   +  +PLH+ C  G   V++ L+     +VN+ +A   + LH+A++ +++ +++ LL +P   ++L +RD  G+TPF TA++  N  AA+ IL   P AA+++D  GRNFLH+A+   + E+V FL+ +  ++N RV DA Q +PLHLA  S   E + R+LILAGA +      ++  LH+A+    +  +S L++N A     D      LH+AVR     +++ LL  S    ++ NLKG N LH L   CR        +I  L L+  P++P++  D  GNT L L  ++  S L   L+  GA LG  N +G  +FN +  ++Q +  LLD L  E  W + + C  C  +F+I  RKHHCRHCGR++C KCS N++PI+KF I KPVRVC VCFN L  G
Sbjct:  496 KHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIR-------GGSDVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGES---------PLWSALEKGYEDVAKILVRHGIDTDCWD-EGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSS---RQPG---PNGEGGDEAQDKASPLHLCCHWGQTKVLQTLIDHGA-NVNLIDAESKSPLHVAIESQYDEIISILLCHPD--IDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFLLAIQVDVNSRVHDANQSSPLHLAAAS-QNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDATDADGNNALHIAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHEL---CRVVEDSTAGLICELFLESMPKYPINIPDMDGNTPLLLSFMRGQSPLCKILVKAGACLGTENKDGINIFNFKLATDQLLHNLLDQLPQESPWAESDYCQHCTNRFTITMRKHHCRHCGRVLCSKCSCNDVPILKFGINKPVRVCTVCFNVLQCG 1117

HSP 2 Score: 155.606 bits (392), Expect = 8.213e-38
Identity = 101/319 (31.66%), Postives = 169/319 (52.98%), Query Frame = 2

Query:   98 EYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNK-IVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLK-SCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIP 1048
            EY K+   Y  L+ KY+  I  S N  +  + +++     V SL+    ++DI I+ Q    P H+I+  A   +W    LSN ++++  +  +++   +++WIY  +L D QN  +   L+K AH   L  L   CE   ++ V   +CI FY  A E     L  +CS++I  +W++    DF  +   +  ++L+ ++ +PLH AV+  R+DVV L I + Y     LVN  SE+  L L++ALSSK  ++ ++L+    AN+N+V+  G+SLL  A++  D FS  FL+   C L+  S   S T + ++ N  P
Sbjct:   22 EYTKLQRCYVELQRKYNENIASSENEESGLSSFLSRLSLTVASLFDKNTYADIYIRSQTRVFPAHKIVLHARSEKWGNDLLSNIQQLDWSDLNEDVVLSLLRWIY-TDLIDLQNDGLALDLLKAAHRFGLPSLLGICERALVTSVGVRSCIRFYCVAEEVGASTLLEYCSSIISTHWDDLTTDDFQHMSGPLLFEMLKTKTKHPLHAAVRLLREDVVSLCI-QKYGN--SLVNTFSENGILPLEMALSSKNAKIAKSLVDNGMANINAVNMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKPSSDTALHIICNYGP 336

HSP 3 Score: 62.3882 bits (150), Expect = 3.352e-9
Identity = 146/649 (22.50%), Postives = 246/649 (37.90%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGN------IEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQ------------------------------TLLHRTILEMKEQAANFLISRG---------CDTISTMENKNPSNSISNYES-------------NNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-----------NPKYKLNLSIR-------------------DHQGHTPFHTAMELSNQKAARSILQYHPQAADEID----NLGRNFLHVAVQTMNREAVYFLIQVNANL--------NIRVKDAFQ--YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLL-ENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILH--ILSNNCRENGIVIFSLILDHYPEFPVDEK--DACGNTALFLCALKDNSRLGVALLLKGASL 3808
            P  +A+ +KN KI    +  D G   +N +  +  G S     L NG     + + ++    D  +           + LH+    G       +E V+ +++   +IN+++I   TPL +A  + N+++V++L      PNI  N+ + +    L   L +++ +  F IA IL+  GA  D  +    D+  Q                              T LH   L         LI  G         C   S +     +N+I   E+             N   I G++PL +   +   ++V  L+     DVN +N    + LH ++K     +   LL           N    L+LSI+                   +  G +P  +A+E   +  A+ IL  H    D  D       +  LH A+         FLIQ   +L        N    D  Q   +PLHL    G  + ++++LI  GAN+     E ++ LH+A+  +   IIS LL         +D    TP   A+   N +  + +L    T  +  +++G N LH  IL ++      V+F L +    +  V+ +  DA  ++ L L A   N  +   L+L GA +
Sbjct:  259 PLEMALSSKNAKIAKSLV--DNGMANINAV--NMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKP------SSDTALHIICNYGPDNTPEIMEVVKKILQRQLNINIQNIKGETPLHIAIARRNVEMVKLLL---KVPNIDINLRTYDEKCALE--LSLSMGDHEFLIASILLSMGARTDRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLTALHIAALNNMPNLVKKLIVNGASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIRGGS-DVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGESPLWSALEKGYEDVAK-ILVRHGIDTDCWDEGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSSRQPGPNGEGGDEAQDKASPLHLCCHWGQTK-VLQTLIDHGANVNLIDAESKSPLHVAIESQYDEIISILLCHPDIDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLES---VLFLLAI----QVDVNSRVHDANQSSPLHLAAASQNEMITRNLILAGARM 882

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Fly
Match: CG41099 (gene:FBgn0039955 transcript:FBtr0113990)

HSP 1 Score: 344.739 bits (883), Expect = 3.802e-99
Identity = 224/652 (34.36%), Postives = 341/652 (52.30%), Query Frame = 2

Query: 2156 KQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-NPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCR----ENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            K +   L +  H+AV+   I  +  F+      + +++   D  G+SP +LCL     ++   +           S+++    +  S LH ++K  + +   FL++ G DI   + N  + L L+ +    ++V  LC  G   +I  N  S         PLW AL     D+A ILV  G D D W     +   QTLLHR I E KE  A FLI   CD  S+   + P     N E  +   +  +PLH+ C  G   V++ L+     +VN+ +A   + LH+A++ +++ +++ LL +P   ++L +RD  G+TPF TA++  N  AA+ IL   P AA+++D  GRNFLH+A+   + E+V FL+ +  ++N RV DA Q +PLHLA  S   E + R+LILAGA +      ++  LH+A+    +  +S L++N A     D      LH+AVR     +++ LL  S    ++ NLKG N LH L   CR        +I  L L+  P++P++  D  GNT L L  ++  S L   L+  GA LG  N +G  +FN +  ++Q +  LLD L  E  W + + C  C  +F+I  RKHHCRHCGR++C KCS N++PI+KF I KPVRVC VCFN L  G
Sbjct:  498 KHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIR-------GGSDVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGES---------PLWSALEKGYEDVAKILVRHGIDTDCWD-EGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSS---RQPG---PNGEGGDEAQDKASPLHLCCHWGQTKVLQTLIDHGA-NVNLIDAESKSPLHVAIESQYDEIISILLCHPD--IDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFLLAIQVDVNSRVHDANQSSPLHLAAAS-QNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDATDADGNNALHIAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHEL---CRVVEDSTAGLICELFLESMPKYPINIPDMDGNTPLLLSFMRGQSPLCKILVKAGACLGTENKDGINIFNFKLATDQLLHNLLDQLPQESPWAESDYCQHCTNRFTITMRKHHCRHCGRVLCSKCSCNDVPILKFGINKPVRVCTVCFNVLQCG 1119

HSP 2 Score: 155.606 bits (392), Expect = 9.050e-38
Identity = 101/319 (31.66%), Postives = 169/319 (52.98%), Query Frame = 2

Query:   98 EYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNK-IVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLK-SCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIP 1048
            EY K+   Y  L+ KY+  I  S N  +  + +++     V SL+    ++DI I+ Q    P H+I+  A   +W    LSN ++++  +  +++   +++WIY  +L D QN  +   L+K AH   L  L   CE   ++ V   +CI FY  A E     L  +CS++I  +W++    DF  +   +  ++L+ ++ +PLH AV+  R+DVV L I + Y     LVN  SE+  L L++ALSSK  ++ ++L+    AN+N+V+  G+SLL  A++  D FS  FL+   C L+  S   S T + ++ N  P
Sbjct:   24 EYTKLQRCYVELQRKYNENIASSENEESGLSSFLSRLSLTVASLFDKNTYADIYIRSQTRVFPAHKIVLHARSEKWGNDLLSNIQQLDWSDLNEDVVLSLLRWIY-TDLIDLQNDGLALDLLKAAHRFGLPSLLGICERALVTSVGVRSCIRFYCVAEEVGASTLLEYCSSIISTHWDDLTTDDFQHMSGPLLFEMLKTKTKHPLHAAVRLLREDVVSLCI-QKYGN--SLVNTFSENGILPLEMALSSKNAKIAKSLVDNGMANINAVNMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKPSSDTALHIICNYGP 338

HSP 3 Score: 62.003 bits (149), Expect = 3.840e-9
Identity = 128/555 (23.06%), Postives = 214/555 (38.56%), Query Frame = 2

Query: 2447 IEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQ------------------------------TLLHRTILEMKEQAANFLISRG---------CDTISTMENKNPSNSISNYES-------------NNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL-----------NPKYKLNLSIR-------------------DHQGHTPFHTAMELSNQKAARSILQYHPQAADEID----NLGRNFLHVAVQTMNREAVYFLIQVNANL--------NIRVKDAFQ--YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLL-ENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILH--ILSNNCRENGIVIFSLILDHYPEFPVDEK--DACGNTALFLCALKDNSRLGVALLLKGASL 3808
            +E V+ +++   +IN+++I   TPL +A  + N+++V++L      PNI  N+ + +    L   L +++ +  F IA IL+  GA  D  +    D+  Q                              T LH   L         LI  G         C   S +     +N+I   E+             N   I G++PL +   +   ++V  L+     DVN +N    + LH ++K     +   LL           N    L+LSI+                   +  G +P  +A+E   +  A+ IL  H    D  D       +  LH A+         FLIQ   +L        N    D  Q   +PLHL    G  + ++++LI  GAN+     E ++ LH+A+  +   IIS LL         +D    TP   A+   N +  + +L    T  +  +++G N LH  IL ++      V+F L +    +  V+ +  DA  ++ L L A   N  +   L+L GA +
Sbjct:  345 MEVVKKILQRQLNINIQNIKGETPLHIAIARRNVEMVKLLL---KVPNIDINLRTYDEKCALE--LSLSMGDHEFLIASILLSMGARTDRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLTALHIAALNNMPNLVKKLIVNGASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIRGGS-DVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGESPLWSALEKGYEDVAK-ILVRHGIDTDCWDEGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSSRQPGPNGEGGDEAQDKASPLHLCCHWGQTK-VLQTLIDHGANVNLIDAESKSPLHVAIESQYDEIISILLCHPDIDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLES---VLFLLAI----QVDVNSRVHDANQSSPLHLAAASQNEMITRNLILAGARM 884

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0344224)

HSP 1 Score: 145.591 bits (366), Expect = 2.458e-34
Identity = 150/552 (27.17%), Postives = 244/552 (44.20%), Query Frame = 2

Query: 2252 RNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAG--ADVDMWSIHY---KDNYEQ-------------------TLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            +N ++   ++  G +   L   +G I V  ++  R    D  T +         + LH+A   G  E V+ L++    +NV+S N  TPL +A ++++  +VR+L  +GA+ ++     +++GF     PL VA+      +  +L+E+     V + ++H    KD+ +                    T LH       +  AN LI +G D               NY S  H I   +PLH+A + G  ++V  LL     ++  +   G T LH A +  HE V+  LL  +    +S +   G  P H A +  +  AAR IL YH    DE+       LHVA    +      L+  NA+ N R  + F  TPLH+A      + ++  L+  GA+I+  T      LH+A     + I+ +LL++ AS      + ETPLHLA R    D+I+ LL N +  + ++  + +  LHI S   R   + I  L+L H  +     KD    TAL + A +    +   L+  GA+L     +GFT
Sbjct:   32 KNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKK-------GNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLA----TEDGFT----PLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADV--------------NY-SAKHNI---SPLHVAAKWGKTNMVSLLLEKGG-NIEAKTRDGLTPLHCAARSGHEQVVDMLL--ERGAPISAKTKNGLAPLHMAAQGEHVDAAR-ILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGF--TPLHIACKKNRLK-VVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGA-QVDARAREQQTPLHIAS---RLGNVDIVMLLLQHGAQVDATTKDM--YTALHIAAKEGQDEVAAVLIENGAALDAATKKGFT 537

HSP 2 Score: 118.627 bits (296), Expect = 3.563e-26
Identity = 139/570 (24.39%), Postives = 234/570 (41.05%), Query Frame = 2

Query: 2132 KGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKT--------------------------SEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITS-------NIISQEGFIEL------------------NCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYI---------------EGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIR-SLILA--GANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI 3634
            KG  VN   +  I   +P H+A K     +++L +  ++G N +     D  G +P      +G   V D + ER      KT                          + +D++ +D  + LH+A   G++   + L+    D N R++N  TPL +A +K+ + +V +L   GA  + T+       ++ +  G + +                    PL +A    + DI  IL+  GA VD      +   +QT LH             L+  G    +T ++   +  I+  E  +                  +G TPLH+  + G   V + LL   + DV+ Q   G T LH+A  + ++ V   LL      + + ++  GHTP H A   +    A ++L+Y   A  E    G   LH++ Q  + E    LI+  A +N   K+    TP+HL     A ED +  + IL   GANI   T      LH+A    +  ++ FLL+NGA+     +   TPLH   + G+  ++  LL + +    ++ + G+  LHI
Sbjct:  227 KGADVNYSAKHNI---SPLHVAAKWGKTNMVSLLL--EKGGN-IEAKTRD--GLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDA-----RAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQ-LLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKN--GHTPLHIAARKNQMDIATTLLEYGALANAE-SKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGL--TPMHLC----AQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANA-NAQTVNGQTPLHI 772

HSP 3 Score: 76.6406 bits (187), Expect = 1.909e-13
Identity = 93/374 (24.87%), Postives = 151/374 (40.37%), Query Frame = 2

Query: 2894 EGNTPLHMACQMG-LESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNP-------------------------------KYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQ------------YHP------QAADEI-------DNLGR---NFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            +GNT    A + G LE V+++L   N ID+N  NA G  +LHLA K  H  V++ LL                                 ++  +++++   G TP + A + ++    R +L             + P      Q  D++       D  G+     LH+A +  + +A   L+  + N ++  K  F  TPLH+A   G  +++   LI  GA++        + LH+A    +  ++S LLE G +   +     TPLH A R G+  ++  LL   +  I +K   G   LH+ +     +   I       Y   PVDE      TAL + A   + R+   LL + A        GFT
Sbjct:   10 DGNTSFLRAARAGNLERVLEHL--KNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGF--TPLHIASHYGN-QNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGA-PISAKTKNGLAPLHMAAQGEHVDAARILL-----YHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFT 372

HSP 4 Score: 55.8398 bits (133), Expect = 3.821e-7
Identity = 51/187 (27.27%), Postives = 92/187 (49.20%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDM-WSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKID 2977
            LHL+ ++G+ E    LI+    +N  + N +TP+ L  ++ N+++  IL  +GA+ ++ +    + G+     PL VA +  + ++   L++ GA+VD   SI Y      T LH+T  +      N L          +E+K  +N+          + G TPLH+A ++G  SV+ +L +  K D
Sbjct:  638 LHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMAT----KAGYT----PLHVASHFGQANMVRFLLQNGANVDAATSIGY------TPLHQTAQQGHCHIVNLL----------LEHKANANA--------QTVNGQTPLHIARKLGYISVLDSLKTITKED 792

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Zebrafish
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 442.58 bits (1137), Expect = 1.596e-133
Identity = 249/647 (38.49%), Postives = 374/647 (57.81%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +P HLA+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+K+ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     ++++++G    + PLW+AL N   DIA  LV  G D   WS       +QTLLHR I E  E  A FLI  GCD  S+   + P     N E +    +G  PLH+A   GLE V + LL     +VN Q++ G   +H+A+    ++V+  LL    ++ L+IRD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+D+ + +PLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S L+ENG   +  D      LHLAV  G ++ ++ LL  S+   ++ NL+G++ +H+L    +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C+ KF +  RKHHCRHCGRL+C KCS+ E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  543 SPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGAD----MSVVNEKG----DPPLWLALENGLEDIASTLVRHGCDATCWS-SGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSS---RRPG---PNGEGDEEARDGQCPLHLAASWGLEEVAQCLLEFGA-NVNAQDSEGRAPIHVAIS-NQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDSAKLSPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLSTICSVLIENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNVDAEAYNLRGQSPMHVLGQYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVTNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECITKFGVTTRKHHCRHCGRLLCHKCSIKEIPIIKFDLNKPVRVCDICFDVLTLG 1164

HSP 2 Score: 223.787 bits (569), Expect = 7.044e-59
Identity = 167/574 (29.09%), Postives = 276/574 (48.08%), Query Frame = 2

Query:   62 ETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTE----DNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGL-EDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNI 1768
            + L KH  LL+QEY K+  K    + +   L   +  P +     D+F   L  IV  LY+ +++SD+ +K+    +  H+ +  A    W+ ++L++  E++L + +  +   +++W Y  +L  N N   L  LMK+A+   L  L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  ++A +   ++++++ YPLH+A+K  R+DVVFLY+ E  +QL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P     E +  +  I   L++ GA+                 NM  N   RT L  A++SGNE V   +L   +C  ++        + K    S               LWLA+  +Y              + + + P+    E+EA P V   S   NS    ++ +G   DA     N    +     +       +   + VN TN + E+  H A    L  L   LLQ GA+PN+
Sbjct:    7 QKLQKHLALLRQEYVKMQQKLVETERRCSVLAAQASVPGSSSQASDSFISRLLAIVSDLYQQEQYSDLKVKIGDQRLSAHKFVLAARSEIWSLANLASTSELDLSDAKPEVAMAMLRWTYTDDLELNGNDGFLIDLMKLANRFQLHLLRERCEKGVMSSVNVRNCIRFYQTAEELDAATLMNYCGEIIASHWDDLRKEDFSTMDAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSKKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGANP----------------NMQ-NSKGRTPLHEAVVSGNEPVFNQLL---QCKQLD-------LELKDHEGST-------------ALWLAL--QY--------------ITVASDPSVNPFEDEA-PVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNL 523

HSP 3 Score: 76.2554 bits (186), Expect = 2.603e-13
Identity = 113/449 (25.17%), Postives = 178/449 (39.64%), Query Frame = 2

Query: 2675 IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCD----TISTMENKNPSNSISNYESNNHYIEGNTPLHMACQM-----------GLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAA-----------------------DEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLA------------IISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKM-------------ETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            IA  LV   ADVDM      D    +LLH+ I    E A+ FLI         T+  +E                     TPLH+ C             G+  + + LL +   + N+QN+ G T LH AV   +E V   LL  K +L+L ++DH+G T    A++     +  S+  +  +A                        D  D  G   +  A    +  A  FL    A +N   K  +  TPLH A            +  GA  +L   + L G    ++ + +Q+ LHLA++H    ++S +LE  A+  H  N +             +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  ++  G TAL L A+ +   L V A+  +GA +   N +G
Sbjct:  275 IATTLVNNKADVDM-----VDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVE---------------------TPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGA-NPNMQNSKGRTPLHEAVVSGNEPVFNQLLQCK-QLDLELKDHEGSTALWLALQYITVASDPSVNPFEDEAPVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNK--WGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIKR-QDSKSALF--LLEHQADINVRTQE--GQTALQL-AISNQLPLVVDAICTRGADMSVVNEKG 686

HSP 4 Score: 64.3142 bits (155), Expect = 1.024e-9
Identity = 93/422 (22.04%), Postives = 169/422 (40.05%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGF-----IELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N  +    TPL  A       +   L   GA+PN+ ++I    G      +    PL +A+ +   D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA +   +S     L  ++ D+NV+   G T+L LA+  +   V+  +       ++S+ + +G  P   A+E   +  A +++++   A       G   +  LH A+   N     FLI+   ++N   +                PLHLA   G  E++ + L+  GAN+  +  E +  +H+A+ +++  II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  480 FLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIKRQ-DSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICT--RGADMSVVNEKGDPPLWLALENGLEDIASTLVRHGCDATCWSSGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSSRRPGPNGEGDEEARDGQCPLHLAASWGL-EEVAQCLLEFGANVNAQDSEGRAPIHVAISNQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 879

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Zebrafish
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 441.81 bits (1135), Expect = 2.440e-133
Identity = 249/647 (38.49%), Postives = 374/647 (57.81%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +P HLA+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+K+ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     ++++++G    + PLW+AL N   DIA  LV  G D   WS       +QTLLHR I E  E  A FLI  GCD  S+   + P     N E +    +G  PLH+A   GLE V + LL     +VN Q++ G   +H+A+    ++V+  LL    ++ L+IRD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+D+ + +PLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S L+ENG   +  D      LHLAV  G ++ ++ LL  S+   ++ NL+G++ +H+L    +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C+ KF +  RKHHCRHCGRL+C KCS+ E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  543 SPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGAD----MSVVNEKG----DPPLWLALENGLEDIASTLVRHGCDATCWS-SGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSS---RRPG---PNGEGDEEARDGQCPLHLAASWGLEEVAQCLLEFGA-NVNAQDSEGRAPIHVAIS-NQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDSAKLSPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLSTICSVLIENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNVDAEAYNLRGQSPMHVLGQYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVTNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECITKFGVTTRKHHCRHCGRLLCHKCSIKEIPIIKFDLNKPVRVCDICFDVLTLG 1164

HSP 2 Score: 223.402 bits (568), Expect = 9.817e-59
Identity = 167/574 (29.09%), Postives = 276/574 (48.08%), Query Frame = 2

Query:   62 ETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTE----DNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGL-EDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNI 1768
            + L KH  LL+QEY K+  K    + +   L   +  P +     D+F   L  IV  LY+ +++SD+ +K+    +  H+ +  A    W+ ++L++  E++L + +  +   +++W Y  +L  N N   L  LMK+A+   L  L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  ++A +   ++++++ YPLH+A+K  R+DVVFLY+ E  +QL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P     E +  +  I   L++ GA+                 NM  N   RT L  A++SGNE V   +L   +C  ++        + K    S               LWLA+  +Y              + + + P+    E+EA P V   S   NS    ++ +G   DA     N    +     +       +   + VN TN + E+  H A    L  L   LLQ GA+PN+
Sbjct:    7 QKLQKHLALLRQEYVKMQQKLVETERRCSVLAAQASVPGSSSQASDSFISRLLAIVSDLYQQEQYSDLKVKIGDQRLSAHKFVLAARSEIWSLANLASTSELDLSDAKPEVAMAMLRWTYTDDLELNGNDGFLIDLMKLANRFQLHLLRERCEKGVMSSVNVRNCIRFYQTAEELDAATLMNYCGEIIASHWDDLRKEDFSTMDAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSKKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGANP----------------NMQ-NSKGRTPLHEAVVSGNEPVFNQLL---QCKQLD-------LELKDHEGST-------------ALWLAL--QY--------------ITVASDPSVNPFEDEA-PVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNL 523

HSP 3 Score: 75.8702 bits (185), Expect = 3.084e-13
Identity = 113/449 (25.17%), Postives = 178/449 (39.64%), Query Frame = 2

Query: 2675 IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCD----TISTMENKNPSNSISNYESNNHYIEGNTPLHMACQM-----------GLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAA-----------------------DEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLA------------IISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKM-------------ETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            IA  LV   ADVDM      D    +LLH+ I    E A+ FLI         T+  +E                     TPLH+ C             G+  + + LL +   + N+QN+ G T LH AV   +E V   LL  K +L+L ++DH+G T    A++     +  S+  +  +A                        D  D  G   +  A    +  A  FL    A +N   K  +  TPLH A            +  GA  +L   + L G    ++ + +Q+ LHLA++H    ++S +LE  A+  H  N +             +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  ++  G TAL L A+ +   L V A+  +GA +   N +G
Sbjct:  275 IATTLVNNKADVDM-----VDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVE---------------------TPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGA-NPNMQNSKGRTPLHEAVVSGNEPVFNQLLQCK-QLDLELKDHEGSTALWLALQYITVASDPSVNPFEDEAPVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNK--WGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIKR-QDSKSALF--LLEHQADINVRTQE--GQTALQL-AISNQLPLVVDAICTRGADMSVVNEKG 686

HSP 4 Score: 64.3142 bits (155), Expect = 1.163e-9
Identity = 92/422 (21.80%), Postives = 170/422 (40.28%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNI-----ISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N  +    TPL  A       +   L   GA+PN+ ++I     + +   +    PL +A+ +   D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA +   +S     L  ++ D+NV+   G T+L LA+  +   V+  +       ++S+ + +G  P   A+E   +  A +++++   A       G   +  LH A+   N     FLI+   ++N   +                PLHLA   G  E++ + L+  GAN+  +  E +  +H+A+ +++  II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  480 FLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIKRQ-DSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICT--RGADMSVVNEKGDPPLWLALENGLEDIASTLVRHGCDATCWSSGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSSRRPGPNGEGDEEARDGQCPLHLAASWGL-EEVAQCLLEFGANVNAQDSEGRAPIHVAISNQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 879

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Zebrafish
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 434.491 bits (1116), Expect = 1.481e-130
Identity = 248/647 (38.33%), Postives = 372/647 (57.50%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +P HLA+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+K+ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     ++++++G    + PLW+AL N   DIA  LV  G D   WS       +QTLLHR I E  E  A FLI  GCD  S+   + P     N E +    +G  PLH+A   GLE V + LL     +VN Q++ G   +H+A+    ++V+  LL    ++ L+IRD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+D+ + +PLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S L+ENG   +  D      LHLAV  G ++ ++ LL  S+   ++ NL  ++ +H+L    +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C+ KF +  RKHHCRHCGRL+C KCS+ E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  543 SPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGAD----MSVVNEKG----DPPLWLALENGLEDIASTLVRHGCDATCWS-SGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSS---RRPG---PNGEGDEEARDGQCPLHLAASWGLEEVAQCLLEFGA-NVNAQDSEGRAPIHVAIS-NQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDSAKLSPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLSTICSVLIENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNVDAEAYNLS-QSPMHVLGQYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVTNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECITKFGVTTRKHHCRHCGRLLCHKCSIKEIPIIKFDLNKPVRVCDICFDVLTLG 1163

HSP 2 Score: 223.787 bits (569), Expect = 7.139e-59
Identity = 167/574 (29.09%), Postives = 276/574 (48.08%), Query Frame = 2

Query:   62 ETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTE----DNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGL-EDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNI 1768
            + L KH  LL+QEY K+  K    + +   L   +  P +     D+F   L  IV  LY+ +++SD+ +K+    +  H+ +  A    W+ ++L++  E++L + +  +   +++W Y  +L  N N   L  LMK+A+   L  L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  ++A +   ++++++ YPLH+A+K  R+DVVFLY+ E  +QL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P     E +  +  I   L++ GA+                 NM  N   RT L  A++SGNE V   +L   +C  ++        + K    S               LWLA+  +Y              + + + P+    E+EA P V   S   NS    ++ +G   DA     N    +     +       +   + VN TN + E+  H A    L  L   LLQ GA+PN+
Sbjct:    7 QKLQKHLALLRQEYVKMQQKLVETERRCSVLAAQASVPGSSSQASDSFISRLLAIVSDLYQQEQYSDLKVKIGDQRLSAHKFVLAARSEIWSLANLASTSELDLSDAKPEVAMAMLRWTYTDDLELNGNDGFLIDLMKLANRFQLHLLRERCEKGVMSSVNVRNCIRFYQTAEELDAATLMNYCGEIIASHWDDLRKEDFSTMDAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSKKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGANP----------------NMQ-NSKGRTPLHEAVVSGNEPVFNQLL---QCKQLD-------LELKDHEGST-------------ALWLAL--QY--------------ITVASDPSVNPFEDEA-PVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNL 523

HSP 3 Score: 76.2554 bits (186), Expect = 2.412e-13
Identity = 113/449 (25.17%), Postives = 178/449 (39.64%), Query Frame = 2

Query: 2675 IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCD----TISTMENKNPSNSISNYESNNHYIEGNTPLHMACQM-----------GLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAA-----------------------DEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLA------------IISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKM-------------ETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            IA  LV   ADVDM      D    +LLH+ I    E A+ FLI         T+  +E                     TPLH+ C             G+  + + LL +   + N+QN+ G T LH AV   +E V   LL  K +L+L ++DH+G T    A++     +  S+  +  +A                        D  D  G   +  A    +  A  FL    A +N   K  +  TPLH A            +  GA  +L   + L G    ++ + +Q+ LHLA++H    ++S +LE  A+  H  N +             +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  ++  G TAL L A+ +   L V A+  +GA +   N +G
Sbjct:  275 IATTLVNNKADVDM-----VDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVE---------------------TPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGA-NPNMQNSKGRTPLHEAVVSGNEPVFNQLLQCK-QLDLELKDHEGSTALWLALQYITVASDPSVNPFEDEAPVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNK--WGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIKR-QDSKSALF--LLEHQADINVRTQE--GQTALQL-AISNQLPLVVDAICTRGADMSVVNEKG 686

HSP 4 Score: 64.6994 bits (156), Expect = 9.732e-10
Identity = 92/422 (21.80%), Postives = 170/422 (40.28%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNI-----ISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N  +    TPL  A       +   L   GA+PN+ ++I     + +   +    PL +A+ +   D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA +   +S     L  ++ D+NV+   G T+L LA+  +   V+  +       ++S+ + +G  P   A+E   +  A +++++   A       G   +  LH A+   N     FLI+   ++N   +                PLHLA   G  E++ + L+  GAN+  +  E +  +H+A+ +++  II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  480 FLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIKRQ-DSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICT--RGADMSVVNEKGDPPLWLALENGLEDIASTLVRHGCDATCWSSGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSSRRPGPNGEGDEEARDGQCPLHLAASWGL-EEVAQCLLEFGANVNAQDSEGRAPIHVAISNQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 879

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Zebrafish
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 434.491 bits (1116), Expect = 1.481e-130
Identity = 248/647 (38.33%), Postives = 372/647 (57.50%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +P HLA+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+K+ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     ++++++G    + PLW+AL N   DIA  LV  G D   WS       +QTLLHR I E  E  A FLI  GCD  S+   + P     N E +    +G  PLH+A   GLE V + LL     +VN Q++ G   +H+A+    ++V+  LL    ++ L+IRD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+D+ + +PLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S L+ENG   +  D      LHLAV  G ++ ++ LL  S+   ++ NL  ++ +H+L    +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C+ KF +  RKHHCRHCGRL+C KCS+ E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  543 SPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGAD----MSVVNEKG----DPPLWLALENGLEDIASTLVRHGCDATCWS-SGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSS---RRPG---PNGEGDEEARDGQCPLHLAASWGLEEVAQCLLEFGA-NVNAQDSEGRAPIHVAIS-NQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDSAKLSPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLSTICSVLIENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNVDAEAYNLS-QSPMHVLGQYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVTNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECITKFGVTTRKHHCRHCGRLLCHKCSIKEIPIIKFDLNKPVRVCDICFDVLTLG 1163

HSP 2 Score: 223.787 bits (569), Expect = 7.139e-59
Identity = 167/574 (29.09%), Postives = 276/574 (48.08%), Query Frame = 2

Query:   62 ETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTE----DNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGL-EDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNI 1768
            + L KH  LL+QEY K+  K    + +   L   +  P +     D+F   L  IV  LY+ +++SD+ +K+    +  H+ +  A    W+ ++L++  E++L + +  +   +++W Y  +L  N N   L  LMK+A+   L  L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  ++A +   ++++++ YPLH+A+K  R+DVVFLY+ E  +QL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P     E +  +  I   L++ GA+                 NM  N   RT L  A++SGNE V   +L   +C  ++        + K    S               LWLA+  +Y              + + + P+    E+EA P V   S   NS    ++ +G   DA     N    +     +       +   + VN TN + E+  H A    L  L   LLQ GA+PN+
Sbjct:    7 QKLQKHLALLRQEYVKMQQKLVETERRCSVLAAQASVPGSSSQASDSFISRLLAIVSDLYQQEQYSDLKVKIGDQRLSAHKFVLAARSEIWSLANLASTSELDLSDAKPEVAMAMLRWTYTDDLELNGNDGFLIDLMKLANRFQLHLLRERCEKGVMSSVNVRNCIRFYQTAEELDAATLMNYCGEIIASHWDDLRKEDFSTMDAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSKKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGANP----------------NMQ-NSKGRTPLHEAVVSGNEPVFNQLL---QCKQLD-------LELKDHEGST-------------ALWLAL--QY--------------ITVASDPSVNPFEDEA-PVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNL 523

HSP 3 Score: 76.2554 bits (186), Expect = 2.412e-13
Identity = 113/449 (25.17%), Postives = 178/449 (39.64%), Query Frame = 2

Query: 2675 IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCD----TISTMENKNPSNSISNYESNNHYIEGNTPLHMACQM-----------GLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAA-----------------------DEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLA------------IISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKM-------------ETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            IA  LV   ADVDM      D    +LLH+ I    E A+ FLI         T+  +E                     TPLH+ C             G+  + + LL +   + N+QN+ G T LH AV   +E V   LL  K +L+L ++DH+G T    A++     +  S+  +  +A                        D  D  G   +  A    +  A  FL    A +N   K  +  TPLH A            +  GA  +L   + L G    ++ + +Q+ LHLA++H    ++S +LE  A+  H  N +             +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  ++  G TAL L A+ +   L V A+  +GA +   N +G
Sbjct:  275 IATTLVNNKADVDM-----VDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVE---------------------TPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGA-NPNMQNSKGRTPLHEAVVSGNEPVFNQLLQCK-QLDLELKDHEGSTALWLALQYITVASDPSVNPFEDEAPVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNK--WGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIKR-QDSKSALF--LLEHQADINVRTQE--GQTALQL-AISNQLPLVVDAICTRGADMSVVNEKG 686

HSP 4 Score: 64.6994 bits (156), Expect = 9.732e-10
Identity = 92/422 (21.80%), Postives = 170/422 (40.28%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNI-----ISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N  +    TPL  A       +   L   GA+PN+ ++I     + +   +    PL +A+ +   D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA +   +S     L  ++ D+NV+   G T+L LA+  +   V+  +       ++S+ + +G  P   A+E   +  A +++++   A       G   +  LH A+   N     FLI+   ++N   +                PLHLA   G  E++ + L+  GAN+  +  E +  +H+A+ +++  II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  480 FLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIKRQ-DSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICT--RGADMSVVNEKGDPPLWLALENGLEDIASTLVRHGCDATCWSSGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSSRRPGPNGEGDEEARDGQCPLHLAASWGL-EEVAQCLLEFGANVNAQDSEGRAPIHVAISNQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 879

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Zebrafish
Match: ank2b (ankyrin 2b, neuronal [Source:ZFIN;Acc:ZDB-GENE-041010-165])

HSP 1 Score: 130.954 bits (328), Expect = 6.777e-30
Identity = 140/539 (25.97%), Postives = 235/539 (43.60%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHY---KDNYEQTLL-----HRTILEMKE--------------QAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLLDSLSSEPN 3907
            + S +D       + LH+A   G  + V+ L K G +IN +S N  TPL +A++++++D+VR L  +G + +I     +++GF     PL +AL      +  IL+E      V + ++H    KD+ +   L     H   ++ K                 A  L++RG     T  N                  G TPLH+A + G  ++V +LL      ++ +   G T LH A +  H+  +  LL  +    +  R   G +P H A +  + +  + +LQ H    D++       LHVA    +      L+   AN N R  + F  TPLH+A      + ++  LI  GA I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G +++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D   A G T L + A + +  +   LL  GA+      +GFT     H++ ++    + KLL    + P+
Sbjct:   87 RGSSVDSATKKGNTALHIASLAGQGDVVKILSKRGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIA----TEDGFT----PLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN------------------GITPLHVASKRGNTNMV-HLLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLL--ERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQ-HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRVK-VMELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQMEVVRCLLRNGA-MVDARAREDQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPL---HVASKYGSLEVAKLLLQRRAPPD 583

HSP 2 Score: 108.612 bits (270), Expect = 4.852e-23
Identity = 108/403 (26.80%), Postives = 181/403 (44.91%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESN------------NHYI---EGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLI---RSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLL 3574
            LH+A KK  ++ ++ LIK G  I   + + +TP+ +A    +++IV +L  +GA P++ SNI  +         L +A    + ++   L+  GA VD      +   +QT LH      K +    L+       +   N      I+  E +             H +   +G TPLH+A + G   V K LL       +     G T LH+A  + ++ V   LL+     + + ++  G+TP H A + +  + A ++LQY  +   +    G   +H+A Q  + E    L+Q  A +N+  K     T LHLA    A ED +     L+  GAN+  +T      L +A  +    +++FLL++GAS + +     TPLH A + GN  +I  LL
Sbjct:  395 LHIACKKNRVKVMELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDV-SNIRGETA-------LHMAARAGQMEVVRCLLRNGAMVDA-----RAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLLQRRAPPDSAGKQNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKN--GYTPLHIAAKKNQMEIATTLLQYGAETNIQTKQ-GVMPIHLASQEGHSEMAALLLQRGAQVNVTTKSGL--TSLHLA----AQEDKVGVGEILVKQGANLDQQTKLGYTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLL 775

HSP 3 Score: 100.138 bits (248), Expect = 1.828e-20
Identity = 121/511 (23.68%), Postives = 212/511 (41.49%), Query Frame = 2

Query: 2387 IDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLL---ANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT-LFNSEHISEQFILKLLDSLSSEPN 3907
            +D + +D  + LH+A   G+    + L+    + N R++N  TPL +A +K+ + ++ +L   GA        I++ G      P+ VA      +I  +L++ GA  D+ +I             T L M  +A    + R       M +                 E  TPLH+A ++G   +V+ LL  +    +   A G T LH+A +  H  V T LL      +L+ +  +G TP H A +  + + A+ +LQ            G   LHVA    N++    L+   A+ +   K+   YTPLH+A                          K+N + +A         + LL+ GA T+ Q  +   P+HLA + G+ ++   LL   A  + T KS    G   LH+ +   +E+ + +  +++       +D++   G T L +     N+++   LL  GAS+      G+T L  +       I+ +L    ++PN
Sbjct:  351 VDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLIKYGA----FIQAITESGLT----PIHVAAFMGHLNIVLLLLQNGASPDVSNIR----------GETALHMAARAGQMEVVRCLLRNGAMVDARAR-------------EDQTPLHIASRLGKTEIVQ-LLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATK--KGFTPLHVASKYGSLEVAKLLLQRRAPPDSAGKQNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNG--YTPLHIA-------------------------AKKNQMEIA---------TTLLQYGAETNIQTKQGVMPIHLASQEGHSEMAALLLQRGAQVNVTTKS----GLTSLHLAA---QEDKVGVGEILVKQGAN--LDQQTKLGYTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPN 782

HSP 4 Score: 70.4774 bits (171), Expect = 1.733e-11
Identity = 89/406 (21.92%), Postives = 156/406 (38.42%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWS------IHYKDNYEQTLLHRTILEMK-----------------------EQAANFLISRGCDTISTMEN----------KNP---SNSISNY--ESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVK------------------------FRHEAVLTHLLNPKY-----KLNLSIRDH--QGHTPFHTAMELSNQKAARSILQY 3172
            TP H+A K   +K++ L I +      +       +G +P  +  + G +++   + +     D          I  ++ LH+A + G +E V+ L++ G  ++ R+    TPL +A+     +IV++L    A P+  +      G+     PL +A      D+  +L+EAGA   + +      +H    Y    + + +L+ +                       ++ A  L+ +G    +T +N          KN    + ++  Y  E+N    +G  P+H+A Q G  S +  LL      VNV   +G TSLHLA +                        +    V  H  N K      K   S+ D    G+TP H A +  N      +LQY
Sbjct:  393 TPLHIACKKNRVKVMELLIKYGAFIQAIT-----ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSN-------IRGETALHMAARAGQMEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAAT----ANGYT----PLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLLQRRAPPDSAGKQNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYGAETNIQTKQGVMPIHLASQEG-HSEMAALLLQRGAQVNVTTKSGLTSLHLAAQEDKVGVGEILVKQGANLDQQTKLGYTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLLQY 777

HSP 5 Score: 54.299 bits (129), Expect = 1.319e-6
Identity = 53/218 (24.31%), Postives = 95/218 (43.58%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEM-----KEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHL 3058
            LH+A KK  +E    L++ G + N+++   + P+ LA+++ + ++  +L   GA  N+T+    + G   L+    +A    +  + +ILV+ GA++D          +QT L  T L +       +  NFL+  G                     N+    G TPLH A Q G   ++  LL        + N  G T+L +A +  + +V+  L
Sbjct:  627 LHIAAKKNQMEIATTLLQYGAETNIQTKQGVMPIHLASQEGHSEMAALLLQRGAQVNVTT----KSGLTSLH----LAAQEDKVGVGEILVKQGANLD----------QQTKLGYTPLIVACHYGNAKMVNFLLKSGASV------------------NDKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPNAITN--GNTALAIARRLGYISVVDTL 806

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Xenopus
Match: cilp (cartilage intermediate layer protein [Source:Xenbase;Acc:XB-GENE-922666])

HSP 1 Score: 455.292 bits (1170), Expect = 6.573e-139
Identity = 258/650 (39.69%), Postives = 378/650 (58.15%), Query Frame = 2

Query: 2174 LCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLN-PKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA +     +V  +C  GAD ++T     ++G    N PLW+AL N + DIA  LV  G D   W        +QTLLHR I E KEQ A F+I  GCD  ST   + P     N E      +G TPLH+A   GLE VV+ LL     +VN Q+A G T +H+A+  +H  ++  L++ P  +LN  +RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   S  D      LHLA+  G ++ I+ LL   +   ++ NL+G++ +HIL    +EN   I  L L+  P++P+D+ DA GNT L L  +K N+ L  A++  GA LG  N++G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  457 LQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICTRGADMSVTD----EQG----NPPLWLALENEQEDIASTLVRHGCDATFWGPG-PSGCQQTLLHRAIDENKEQIACFIIRSGCDVNST---RKPG---PNGEGEEEARDGQTPLHLAASWGLEEVVQCLLEFGA-NVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLN--VRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPVICSVLLENGVDFSAADENGNNALHLAIMHGRLNNIRCLLTECNVDAEALNLRGQSPMHILGQYGKENAAAISELFLECMPQYPLDKPDAEGNTVLLLAYMKGNANLCRAIVKAGARLGVNNSQGINIFNYQVATKQLLFRLLDMLSQEPPWCDGSNCYECAAKFGVTTRKHHCRHCGRLLCSKCSTKEIPIIKFDLNKPVRVCDICFDVLTLG 1080

HSP 2 Score: 145.206 bits (365), Expect = 2.579e-34
Identity = 70/180 (38.89%), Postives = 117/180 (65.00%), Query Frame = 2

Query:  500 RCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLAN 1039
            RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  SQL   +N + ++ +L LDLALS +   +  TL+ + A+++ +D  G SLLHKAI R D+F+  FLI+NG  +N  +    QTP+ L+A+
Sbjct:   68 RCEKGVMSLVNVRNCIRFYQTAEELNANALLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTQFPLHKAIKLEREDVVFLYLIEMDSQLPGKLNELDQNGDLSLDLALSRRLESIATTLVNNKADVDMMDKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVAS 247

HSP 3 Score: 79.337 bits (194), Expect = 4.078e-14
Identity = 126/536 (23.51%), Postives = 209/536 (38.99%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIF--------HDEGRNKVNWLMNDYAGES------PFT-LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSN--IISQEG--------FIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA---ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            +P H AV  +N  + N  +          D   +   WL   Y   S      PF  + + NG     +    RLIK    T   D +  +   LL  A   GN  A  FL   G  +N ++    +PL  A      ++   L   GA+PNI +   I S  G           L  PL +A+     D+  +++E  A+          +     KD+ EQT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA+K +   V+  +       ++S+ D QG+ P   A+E   +  A +++++   A           +  LH A+     +   F+I+   ++N   K               TPLHLA   G  E++++ L+  GAN+  +  E +  +H+A+ ++   II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  284 SPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKQGSNTDAPDTVTGN--CLLQRAAAAGNEAASLFLATHGAKVNHKNKWGESPLHTACRHGLSNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLGSGASINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICT--RGADMSVTDEQGNPPLWLALENEQEDIASTLVRHGCDATFWGPGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNSTRKPGPNGEGEEEARDGQTPLHLAASWGL-EEVVQCLLEFGANVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLNVRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 795

HSP 4 Score: 63.929 bits (154), Expect = 2.001e-9
Identity = 120/477 (25.16%), Postives = 193/477 (40.46%), Query Frame = 2

Query: 2600 NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            N + Q G + L+    +AL+     IA  LV   ADVDM      D    +LLH+ I    + AANFLI  G   +  +  E + P + +++    +  +E                         G +PLH A     E V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I Q  +  A D +   G   L  A    N  A  FL    A +N   K+ +  +PLH A   G   +L   L+  GAN   +T E                   Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+K+   L V A+  +GA +   + +G
Sbjct:  165 NELDQNGDLSLD----LALSRRLESIATTLVNNKADVDMM-----DKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTVKDRSVEVMSDIAQIAEALLKAGANPNMQDSKGRSPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFDDVPVVNGTSFD-ENSFAARLIKQGSNTDAPDTVT--GNCLLQRAAAAGNEAASLFLATHGAKVN--HKNKWGESPLHTACRHGL-SNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTRD--GETALQL-AIKNQLPLVVDAICTRGADMSVTDEQG 602

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Xenopus
Match: cilp (cartilage intermediate layer protein [Source:Xenbase;Acc:XB-GENE-922666])

HSP 1 Score: 456.062 bits (1172), Expect = 2.997e-138
Identity = 258/650 (39.69%), Postives = 378/650 (58.15%), Query Frame = 2

Query: 2174 LCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLN-PKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA +     +V  +C  GAD ++T     ++G    N PLW+AL N + DIA  LV  G D   W        +QTLLHR I E KEQ A F+I  GCD  ST   + P     N E      +G TPLH+A   GLE VV+ LL     +VN Q+A G T +H+A+  +H  ++  L++ P  +LN  +RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   S  D      LHLA+  G ++ I+ LL   +   ++ NL+G++ +HIL    +EN   I  L L+  P++P+D+ DA GNT L L  +K N+ L  A++  GA LG  N++G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  543 LQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICTRGADMSVTD----EQG----NPPLWLALENEQEDIASTLVRHGCDATFWG-PGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNST---RKPG---PNGEGEEEARDGQTPLHLAASWGLEEVVQCLLEFGA-NVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLN--VRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPVICSVLLENGVDFSAADENGNNALHLAIMHGRLNNIRCLLTECNVDAEALNLRGQSPMHILGQYGKENAAAISELFLECMPQYPLDKPDAEGNTVLLLAYMKGNANLCRAIVKAGARLGVNNSQGINIFNYQVATKQLLFRLLDMLSQEPPWCDGSNCYECAAKFGVTTRKHHCRHCGRLLCSKCSTKEIPIIKFDLNKPVRVCDICFDVLTLG 1166

HSP 2 Score: 217.624 bits (553), Expect = 8.431e-57
Identity = 170/586 (29.01%), Postives = 291/586 (49.66%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFN----DKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITA 1792
            L KH  LL+QEY K+  K    + K   L   +   ++ D+F   L  IV  L++ +++SD+ IK+    I  H+ +  A    W+ ++L++ +E++L +    +   +++W+Y  EL+  ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  SQL   +N + ++ +L LDLALS +   +  TL+ + A+++ +D  G SLLHKAI R D+F+  FLI+NG  +N  +    QTP+ L+A+        E ++ I  I   L++ GA+                 NM  +   R+ L  A+L+ NE V   +L    C  ++        + K    S               LWLA+      +++ +  D +    D V +    +F        LI+  ++     D+ TGN ++    + G E A++F L  +  K                   VN  N + ES  H A  + L NL   LLQ GA+PNI  + PIT+
Sbjct:    9 LQKHLALLRQEYVKLQQKLAETEKKCTLLAAQANKEASSDSFISRLLSIVAQLFQQEQYSDLMIKVGDKHINAHKFVLAARSEVWSPANLASTKELDLSDSNPEVTMAMLRWVYTDELDLREDDIFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNANALLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTQFPLHKAIKLEREDVVFLYLIEMDSQLPGKLNELDQNGDLSLDLALSRRLESIATTLVNNKADVDMMDKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTVKDRSVEVMSDIAQIAEALLKAGANP----------------NMQDSKGSRSPLHAAVLARNEYVFNQLL---LCKQLD-------LELKDHEGST-------------ALWLAV------QYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKQGSNTDA-PDTVTGNCLLQRAAAAGNEAASLF-LATHGAK-------------------VNHKNKWGESPLHTACRHGLSNLTAELLQQGANPNIQTQEPITS 528

HSP 3 Score: 78.9518 bits (193), Expect = 5.032e-14
Identity = 126/536 (23.51%), Postives = 209/536 (38.99%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIF--------HDEGRNKVNWLMNDYAGES------PFT-LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSN--IISQEG--------FIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA---ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            +P H AV  +N  + N  +          D   +   WL   Y   S      PF  + + NG     +    RLIK    T   D +  +   LL  A   GN  A  FL   G  +N ++    +PL  A      ++   L   GA+PNI +   I S  G           L  PL +A+     D+  +++E  A+          +     KD+ EQT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA+K +   V+  +       ++S+ D QG+ P   A+E   +  A +++++   A           +  LH A+     +   F+I+   ++N   K               TPLHLA   G  E++++ L+  GAN+  +  E +  +H+A+ ++   II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  370 SPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKQGSNTDAPDTVTGN--CLLQRAAAAGNEAASLFLATHGAKVNHKNKWGESPLHTACRHGLSNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLGSGASINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICT--RGADMSVTDEQGNPPLWLALENEQEDIASTLVRHGCDATFWGPGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNSTRKPGPNGEGEEEARDGQTPLHLAASWGL-EEVVQCLLEFGANVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLNVRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 881

HSP 4 Score: 61.2326 bits (147), Expect = 1.385e-8
Identity = 119/478 (24.90%), Postives = 192/478 (40.17%), Query Frame = 2

Query: 2600 NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE--------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            N + Q G + L+    +AL+     IA  LV   ADVDM      D    +LLH+ I    + AANFLI  G   +  +  E + P + +++    +  +E                            +PLH A     E V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I Q  +  A D +   G   L  A    N  A  FL    A +N   K+ +  +PLH A   G   +L   L+  GAN   +T E                   Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+K+   L V A+  +GA +   + +G
Sbjct:  250 NELDQNGDLSLD----LALSRRLESIATTLVNNKADVDMM-----DKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTVKDRSVEVMSDIAQIAEALLKAGANPNMQDSKGSRSPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFDDVPVVNGTSFD-ENSFAARLIKQGSNTDAPDTVT--GNCLLQRAAAAGNEAASLFLATHGAKVN--HKNKWGESPLHTACRHGL-SNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTRD--GETALQL-AIKNQLPLVVDAICTRGADMSVTDEQG 688

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Xenopus
Match: cilp (cartilage intermediate layer protein [Source:Xenbase;Acc:XB-GENE-922666])

HSP 1 Score: 455.677 bits (1171), Expect = 3.028e-138
Identity = 258/650 (39.69%), Postives = 378/650 (58.15%), Query Frame = 2

Query: 2174 LCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLN-PKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA +     +V  +C  GAD ++T     ++G    N PLW+AL N + DIA  LV  G D   W        +QTLLHR I E KEQ A F+I  GCD  ST   + P     N E      +G TPLH+A   GLE VV+ LL     +VN Q+A G T +H+A+  +H  ++  L++ P  +LN  +RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   S  D      LHLA+  G ++ I+ LL   +   ++ NL+G++ +HIL    +EN   I  L L+  P++P+D+ DA GNT L L  +K N+ L  A++  GA LG  N++G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  543 LQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICTRGADMSVTD----EQG----NPPLWLALENEQEDIASTLVRHGCDATFWGPG-PSGCQQTLLHRAIDENKEQIACFIIRSGCDVNST---RKPG---PNGEGEEEARDGQTPLHLAASWGLEEVVQCLLEFGA-NVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLN--VRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPVICSVLLENGVDFSAADENGNNALHLAIMHGRLNNIRCLLTECNVDAEALNLRGQSPMHILGQYGKENAAAISELFLECMPQYPLDKPDAEGNTVLLLAYMKGNANLCRAIVKAGARLGVNNSQGINIFNYQVATKQLLFRLLDMLSQEPPWCDGSNCYECAAKFGVTTRKHHCRHCGRLLCSKCSTKEIPIIKFDLNKPVRVCDICFDVLTLG 1166

HSP 2 Score: 217.624 bits (553), Expect = 9.862e-57
Identity = 170/586 (29.01%), Postives = 291/586 (49.66%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFN----DKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITA 1792
            L KH  LL+QEY K+  K    + K   L   +   ++ D+F   L  IV  L++ +++SD+ IK+    I  H+ +  A    W+ ++L++ +E++L +    +   +++W+Y  EL+  ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  SQL   +N + ++ +L LDLALS +   +  TL+ + A+++ +D  G SLLHKAI R D+F+  FLI+NG  +N  +    QTP+ L+A+        E ++ I  I   L++ GA+                 NM  +   R+ L  A+L+ NE V   +L    C  ++        + K    S               LWLA+      +++ +  D +    D V +    +F        LI+  ++     D+ TGN ++    + G E A++F L  +  K                   VN  N + ES  H A  + L NL   LLQ GA+PNI  + PIT+
Sbjct:    9 LQKHLALLRQEYVKLQQKLAETEKKCTLLAAQANKEASSDSFISRLLSIVAQLFQQEQYSDLMIKVGDKHINAHKFVLAARSEVWSPANLASTKELDLSDSNPEVTMAMLRWVYTDELDLREDDIFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNANALLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTQFPLHKAIKLEREDVVFLYLIEMDSQLPGKLNELDQNGDLSLDLALSRRLESIATTLVNNKADVDMMDKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTVKDRSVEVMSDIAQIAEALLKAGANP----------------NMQDSKGSRSPLHAAVLARNEYVFNQLL---LCKQLD-------LELKDHEGST-------------ALWLAV------QYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKQGSNTDA-PDTVTGNCLLQRAAAAGNEAASLF-LATHGAK-------------------VNHKNKWGESPLHTACRHGLSNLTAELLQQGANPNIQTQEPITS 528

HSP 3 Score: 78.9518 bits (193), Expect = 5.910e-14
Identity = 126/536 (23.51%), Postives = 209/536 (38.99%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIF--------HDEGRNKVNWLMNDYAGES------PFT-LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSN--IISQEG--------FIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA---ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            +P H AV  +N  + N  +          D   +   WL   Y   S      PF  + + NG     +    RLIK    T   D +  +   LL  A   GN  A  FL   G  +N ++    +PL  A      ++   L   GA+PNI +   I S  G           L  PL +A+     D+  +++E  A+          +     KD+ EQT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA+K +   V+  +       ++S+ D QG+ P   A+E   +  A +++++   A           +  LH A+     +   F+I+   ++N   K               TPLHLA   G  E++++ L+  GAN+  +  E +  +H+A+ ++   II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  370 SPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKQGSNTDAPDTVTGN--CLLQRAAAAGNEAASLFLATHGAKVNHKNKWGESPLHTACRHGLSNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLGSGASINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICT--RGADMSVTDEQGNPPLWLALENEQEDIASTLVRHGCDATFWGPGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNSTRKPGPNGEGEEEARDGQTPLHLAASWGL-EEVVQCLLEFGANVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLNVRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 881

HSP 4 Score: 60.8474 bits (146), Expect = 1.655e-8
Identity = 119/478 (24.90%), Postives = 192/478 (40.17%), Query Frame = 2

Query: 2600 NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE--------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            N + Q G + L+    +AL+     IA  LV   ADVDM      D    +LLH+ I    + AANFLI  G   +  +  E + P + +++    +  +E                            +PLH A     E V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I Q  +  A D +   G   L  A    N  A  FL    A +N   K+ +  +PLH A   G   +L   L+  GAN   +T E                   Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+K+   L V A+  +GA +   + +G
Sbjct:  250 NELDQNGDLSLD----LALSRRLESIATTLVNNKADVDMM-----DKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTVKDRSVEVMSDIAQIAEALLKAGANPNMQDSKGSRSPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFDDVPVVNGTSFD-ENSFAARLIKQGSNTDAPDTVT--GNCLLQRAAAAGNEAASLFLATHGAKVN--HKNKWGESPLHTACRHGL-SNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTRD--GETALQL-AIKNQLPLVVDAICTRGADMSVTDEQG 688

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Xenopus
Match: cilp (cartilage intermediate layer protein [Source:Xenbase;Acc:XB-GENE-922666])

HSP 1 Score: 455.677 bits (1171), Expect = 5.745e-138
Identity = 258/650 (39.69%), Postives = 378/650 (58.15%), Query Frame = 2

Query: 2174 LCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLN-PKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA +     +V  +C  GAD ++T     ++G    N PLW+AL N + DIA  LV  G D   W        +QTLLHR I E KEQ A F+I  GCD  ST   + P     N E      +G TPLH+A   GLE VV+ LL     +VN Q+A G T +H+A+  +H  ++  L++ P  +LN  +RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   S  D      LHLA+  G ++ I+ LL   +   ++ NL+G++ +HIL    +EN   I  L L+  P++P+D+ DA GNT L L  +K N+ L  A++  GA LG  N++G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  561 LQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICTRGADMSVTD----EQG----NPPLWLALENEQEDIASTLVRHGCDATFWG-PGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNST---RKPG---PNGEGEEEARDGQTPLHLAASWGLEEVVQCLLEFGA-NVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLN--VRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPVICSVLLENGVDFSAADENGNNALHLAIMHGRLNNIRCLLTECNVDAEALNLRGQSPMHILGQYGKENAAAISELFLECMPQYPLDKPDAEGNTVLLLAYMKGNANLCRAIVKAGARLGVNNSQGINIFNYQVATKQLLFRLLDMLSQEPPWCDGSNCYECAAKFGVTTRKHHCRHCGRLLCSKCSTKEIPIIKFDLNKPVRVCDICFDVLTLG 1184

HSP 2 Score: 217.624 bits (553), Expect = 1.014e-56
Identity = 170/586 (29.01%), Postives = 291/586 (49.66%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFN----DKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITA 1792
            L KH  LL+QEY K+  K    + K   L   +   ++ D+F   L  IV  L++ +++SD+ IK+    I  H+ +  A    W+ ++L++ +E++L +    +   +++W+Y  EL+  ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  SQL   +N + ++ +L LDLALS +   +  TL+ + A+++ +D  G SLLHKAI R D+F+  FLI+NG  +N  +    QTP+ L+A+        E ++ I  I   L++ GA+                 NM  +   R+ L  A+L+ NE V   +L    C  ++        + K    S               LWLA+      +++ +  D +    D V +    +F        LI+  ++     D+ TGN ++    + G E A++F L  +  K                   VN  N + ES  H A  + L NL   LLQ GA+PNI  + PIT+
Sbjct:   27 LQKHLALLRQEYVKLQQKLAETEKKCTLLAAQANKEASSDSFISRLLSIVAQLFQQEQYSDLMIKVGDKHINAHKFVLAARSEVWSPANLASTKELDLSDSNPEVTMAMLRWVYTDELDLREDDIFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNANALLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTQFPLHKAIKLEREDVVFLYLIEMDSQLPGKLNELDQNGDLSLDLALSRRLESIATTLVNNKADVDMMDKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTVKDRSVEVMSDIAQIAEALLKAGANP----------------NMQDSKGSRSPLHAAVLARNEYVFNQLL---LCKQLD-------LELKDHEGST-------------ALWLAV------QYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKQGSNTDA-PDTVTGNCLLQRAAAAGNEAASLF-LATHGAK-------------------VNHKNKWGESPLHTACRHGLSNLTAELLQQGANPNIQTQEPITS 546

HSP 3 Score: 78.9518 bits (193), Expect = 5.326e-14
Identity = 126/536 (23.51%), Postives = 209/536 (38.99%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIF--------HDEGRNKVNWLMNDYAGES------PFT-LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSN--IISQEG--------FIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA---ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            +P H AV  +N  + N  +          D   +   WL   Y   S      PF  + + NG     +    RLIK    T   D +  +   LL  A   GN  A  FL   G  +N ++    +PL  A      ++   L   GA+PNI +   I S  G           L  PL +A+     D+  +++E  A+          +     KD+ EQT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA+K +   V+  +       ++S+ D QG+ P   A+E   +  A +++++   A           +  LH A+     +   F+I+   ++N   K               TPLHLA   G  E++++ L+  GAN+  +  E +  +H+A+ ++   II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  388 SPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKQGSNTDAPDTVTGN--CLLQRAAAAGNEAASLFLATHGAKVNHKNKWGESPLHTACRHGLSNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLGSGASINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICT--RGADMSVTDEQGNPPLWLALENEQEDIASTLVRHGCDATFWGPGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNSTRKPGPNGEGEEEARDGQTPLHLAASWGL-EEVVQCLLEFGANVNTQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLNVRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 899

HSP 4 Score: 61.6178 bits (148), Expect = 1.205e-8
Identity = 119/478 (24.90%), Postives = 192/478 (40.17%), Query Frame = 2

Query: 2600 NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE--------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            N + Q G + L+    +AL+     IA  LV   ADVDM      D    +LLH+ I    + AANFLI  G   +  +  E + P + +++    +  +E                            +PLH A     E V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I Q  +  A D +   G   L  A    N  A  FL    A +N   K+ +  +PLH A   G   +L   L+  GAN   +T E                   Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+K+   L V A+  +GA +   + +G
Sbjct:  268 NELDQNGDLSLD----LALSRRLESIATTLVNNKADVDMM-----DKKGCSLLHKAICRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTVKDRSVEVMSDIAQIAEALLKAGANPNMQDSKGSRSPLHAAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFDDVPVVNGTSFD-ENSFAARLIKQGSNTDAPDTVT--GNCLLQRAAAAGNEAASLFLATHGAKVN--HKNKWGESPLHTACRHGL-SNLTAELLQQGANPNIQTQEPITSPRGPPANSLADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTRD--GETALQL-AIKNQLPLVVDAICTRGADMSVTDEQG 706

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Xenopus
Match: ANK2 (ankyrin 2, neuronal [Source:NCBI gene;Acc:100494806])

HSP 1 Score: 137.502 bits (345), Expect = 1.093e-31
Identity = 149/555 (26.85%), Postives = 250/555 (45.05%), Query Frame = 2

Query: 2306 LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDH--YPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLLDSLSSEPN 3907
            L    G I +  ++ ER        S +D       + LH+A   G  E V+ L+K G +IN +S N  TPL +A ++++ID+V+ L  +GA+     +  +++GF     PL VAL      +  IL+E      V + ++H     + T     +L+    A   +  +++R  ++  T         N N +  + N  +   +   N  TPLH+A + G  ++VK LL    +ID   ++  G T LH A +  H+ V+  LL  +    L  R   G +P H A +  + +  + +LQ H    D++       LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H  +P    D     G T L + A +    +   LL  GA+      +GFT     H++ ++    + KLL    + P+
Sbjct:   49 LAAKEGHIGLVQELMER-------GSAVDSATKKGNTALHIASLAGQAEVVKILVKQGANINAQSQNGFTPLYMAAQENHIDVVKYLLETGAN----QSTATEDGF----TPLAVALQQGHNQVVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLL--ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ-HKAPVDDVTLDYLTSLHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIAS---RLGKTEIVQLLLQHMAHP----DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL---HVAAKYGSLDVAKLLLQRRAPPD 569

HSP 2 Score: 112.079 bits (279), Expect = 5.987e-24
Identity = 114/472 (24.15%), Postives = 208/472 (44.07%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPED-LIRSLILA--GANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSS 3586
            TP H+A K   IK++ L + +      +       +G +P  +  + G +++   + +     D          I  ++ LH+A + G +E V+ L++ G  ++ R+  + TPL +A+     +IV++L    A P+  +      G+     PL ++    + D+A +L+EAG                             AA+ L ++                           +G TPLH+A + G   V K LL   +   +     G T LH+A  + ++ V   LL+      ++ ++  G+TP H A + +  + A ++L Y  +  + + N G   LH+A Q  + + V  L+   AN+++  K+    TPLHLA    A ED +I   IL+  GAN+  +T    + L +A  +  + +++FLL +GA+ + +     TPLH A + G+  +I  LL N +
Sbjct:  379 TPLHIACKKNRIKVMELLVKYGASIQAITE-----SGLTPIHVAAFMGHLNIVLLLLQNGASPDVTN-------IRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATT----NGY----TPLHISAREGQVDVASVLLEAG-----------------------------AAHSLATK---------------------------KGFTPLHVAAKYGSLDVAK-LLLQRRAPPDAAGKNGLTPLHVAAHYDNQKVALLLLDKGASPQVTAKN--GYTPLHIASKKNQMQIATTLLNYGAET-NILTNQGVTPLHLAAQEGHADMVTLLLNKQANIHVGTKNGL--TPLHLA----AQEDRVIVGEILSKNGANLDAQTKLGYSPLIVACHYGNIKMVNFLLNHGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQNGA 764

HSP 3 Score: 103.219 bits (256), Expect = 2.881e-21
Identity = 122/478 (25.52%), Postives = 211/478 (44.14%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRT-----ILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNL-GRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            LH+A   GN+     L+  G  ++  + N +TPL +A+++ N ++V++L   G   +  +    ++G   L+C    A  +    + ++L+E GA                LL RT      L M  Q  +    +       +++K P + ++        ++  T LH+A   G   V K LL   + + N +   G T LH+A K     V+  L+  KY  ++      G TP H A  + +      +LQ    A+ ++ N+ G   LH+A +    E V  L++  A ++ R ++  + TPLH+A   G  E +++ L+   A+    T      LH++    +V + S LLE GA+ S    K  TPLH+A + G++D+ K LL   +      +  G+N L  L      +   +  L+LD      V  K+  G T L + + K+  ++   LL  GA      N+G T
Sbjct:  216 LHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKT----RDGLTPLHC----AARSGHDQVVELLLERGA---------------PLLARTKNGLSPLHMAAQGDHVECVKHL-----LQHKAPVDDVT--------LDYLTSLHVAAHCGHYRVTK-LLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV--KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNG--ASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARARE--EQTPLHIASRLGKTE-IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRA----PPDAAGKNGLTPLHVAAHYDNQKVALLLLDKGASPQVTAKN--GYTPLHIASKKNQMQIATTLLNYGAETNILTNQGVT 643

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Mouse
Match: Ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:MGI Symbol;Acc:MGI:1337008])

HSP 1 Score: 443.351 bits (1139), Expect = 8.493e-134
Identity = 256/652 (39.26%), Postives = 370/652 (56.75%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +I L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA +     +V  +C  GAD ++      ++G    N PLW+AL +   DIA  LV  G D   W         QTLLHR + E  E  A FLI  GCD  S      P    +N E      +G TPLH+A   GLE  V+ LL     +VN Q+A G T +H+A+  +H +V+  LL     + LS+RD QG TPF  AM   N KAA +IL+    AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ LHIL    +EN   IF L L+  PE+P+D+ DA GNT L L  +K N+ L  A++  G  LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC +CF+ L  G
Sbjct:  540 SIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMSVPD----EKG----NPPLWLALASNLEDIASTLVRHGCDATCWGPG-PSGCLQTLLHRAVDENNESTACFLIRSGCDVNS------PRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGA-NVNAQDAEGRTPVHVAISNQH-SVIIQLLISHPNIELSVRDRQGLTPFACAMTYKNNKAAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRALLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRSGVRLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1166

HSP 2 Score: 230.72 bits (587), Expect = 5.510e-61
Identity = 287/1103 (26.02%), Postives = 475/1103 (43.06%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQG----ITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNA-----NRGLLMDLALGKKQNKEILKTT-----HRCKGRKVNSDKQL---TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQS--LLHLAVKKGNIEAVQFLIKIGCDINVRSINK----MTPLLLATEKSNIDIVRILCLSGADPNIT----SNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIS--------------TMENKNPSNSISNYESNNHYI---EGNTPLHMACQ-MGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAAR---SILQYHPQAADEIDNLGRNFLHVAV 3232
            L KH  LL+QEY K+  K    + +   L   +   ++ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ EEI+L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  L A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A   P    A+ ++ +  I   L+Q GA+                 NM  +   RT L L+I++ N+ V   +L   +C  ++        + K    S               LWLA+      +++ +  D       + +P       E  P V   S   NS    ++ +G    A  V+      Q++            ATS   +  N  N + E+  H A  + L NL   LLQ GA+PN+     +                       + K+S +     + IY QT                    P   +M I  +  H   +S+ + +K+NA     N  ++ D +L   +++ +L        H    + + S   +     D  T  H+A++ ++ K   LF+   E +  +N    D  GE+   L + + L  V D I  R           D  V DE+    L LA+     +    L++ GCD             T L  A +++N      L  SG D N      +N   +E   +   PL +A +    +    L+E GA+V+      +D   +T +H  I          LIS     +S              T +N   + +I   ES        +G   LH+A Q   +ESV+  +     ++  VQ+A+  T LHLAV+   E ++ +LL    K+N   +  Q      TA+ L+ Q+      S+L  +      +D  G N LH+AV
Sbjct:    9 LEKHLMLLRQEYVKLQKKLAETEKRCTLLAAQANKENSNESFISRLLAIVAGLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTEEIDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSLSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSHKADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGANP----------------NMQ-DSKGRTPLHLSIMARNDCVFSQLL---QCKQLD-------LELKDHEGST-------------ALWLAV------QYITVSSD------QSVNPF------EDLPVVNGTSFDENSFAARLIQRGSNTDAPDVMTGNCLLQRAAGAGNEAAALFLATSGAHA--NHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALP----------------------VPKESPVLMSSADSIYLQT--------------------PL--HMAIAYN--HPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSA-LFLL--EHQADINVRTQD--GETALQLAIKHQLPLVVDAICTR---------GADMSVPDEKGNPPLWLALASNLEDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNA-----QDAEGRTPVHVAISNQHSVIIQLLISHPNIELSVRDRQGLTPFACAMTYKNNKAAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQ------TALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 980

HSP 3 Score: 75.8702 bits (185), Expect = 3.813e-13
Identity = 140/663 (21.12%), Postives = 245/663 (36.95%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSIN-KMTPL----LLATEKSNID-------IVRILCLSGADPNITS---------NIISQEGFI-----------------ELNCPLWVA--------------------LNNCRFD---IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGC-------------------TSLHLAVKFRHEAVLTHLLNPKYKL-----------NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKD---AFQYT----------------------------PLHLAIISGAPEDLIRSLILAGANIA----NETIEKQNLLHLAVIHERVYIISFLLENG------------ASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCAL 3757
            P H A+K +   ++ L++   + +        D+ G+    L L   L S+   +           +++D +  +  SLLH  +++G++ A  FLIK G  +N  +   + TPL    L + +K + D       I   L  +GA+PN+           +I+++   +                 E +  LW+A                    +N   FD    A  L++ G++ D   +   +     LL R      E AA FL + G                    +N+    G TPLH AC+ GL ++   LL     + N+Q                        T LH+A+ + H  V++ +L  K              + S++D +  T    A+       A  +L       D + + G+  LH+A+Q  + ++  FL++  A++N+R +D   A Q                              PL LA+ S   ED+  +L+  G +        +   Q LLH AV         FL+ +G                 +    +TPLHLA   G  + ++ LL      + +++ +G   +H+  +N      VI  L++ H P   +  +D  G T  F CA+
Sbjct:  221 PLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSH-------KADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHLSIMARNDCVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDLPVVNGTSFDENSFAARLIQRGSNTDAPDVMTGN----CLLQRAAGAGNEAAALFLATSGA------------------HANHRNKWGETPLHTACRHGLANLTAELLQQGA-NPNLQTEEALPVPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSD-GQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMSVPDEKGNPPLWLALASNL-EDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLL-EFGANVNAQDAEGRTPVHVAISNQHS---VIIQLLISH-PNIELSVRDRQGLTP-FACAM 845

HSP 4 Score: 56.6102 bits (135), Expect = 2.864e-7
Identity = 111/452 (24.56%), Postives = 176/452 (38.94%), Query Frame = 2

Query: 2675 IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC---------------------------DTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGAN-------------------IANETIEKQNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            IA  LV   ADVDM      D    +LLH+ I      A+ FLI  G                            D +S M     +   +    N    +G TPLH++     + V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I +     A ++   G   L  A    N  A  FL    A+ N R K  +  TPLH A   G   +L   L+  GAN                    + ++I  Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+K    L V A+  +GA +   + +G
Sbjct:  271 IATTLVSHKADVDM-----VDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHLSIMARNDCVFSQLLQCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFEDLPVVNGTSFD-ENSFAARLIQRGSNTDAPDVMT-GNCLLQRAAGAGNEAAALFLATSGAHANHRNK--WGETPLHTACRHGLA-NLTAELLQQGANPNLQTEEALPVPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTQD--GETALQL-AIKHQLPLVVDAICTRGADMSVPDEKG 688

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Mouse
Match: Ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:MGI Symbol;Acc:MGI:1337008])

HSP 1 Score: 213.772 bits (543), Expect = 8.677e-60
Identity = 123/350 (35.14%), Postives = 202/350 (57.71%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGA 1117
            L KH  LL+QEY K+  K    + +   L   +   ++ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ EEI+L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  L A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A   P    A+ ++ +  I   L+Q GA
Sbjct:    9 LEKHLMLLRQEYVKLQKKLAETEKRCTLLAAQANKENSNESFISRLLAIVAGLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTEEIDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSLSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSHKADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGA 358

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 140.198 bits (352), Expect = 1.425e-32
Identity = 141/503 (28.03%), Postives = 230/503 (45.73%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            + S +D       + LH+A   G  E V+ L+K G +IN +S N  TPL +A ++++ID+V+ L  +GA+ +      +++GF     PL VAL         IL+E      V + ++H     + T     +L+    A   +  +++R  ++  T         N N +  + N  +   +   N  TPLH+A + G  ++VK LL    +ID   ++  G T LH A +  H+ V+  LL  + K  L  R   G +P H A +  + +  + +LQY     D  +D L    LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +    +   LL  GA+      +GFT
Sbjct:   86 RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA----TEDGFT----PLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLL--ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYL--TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFT 565

HSP 2 Score: 108.997 bits (271), Expect = 4.129e-23
Identity = 118/441 (26.76%), Postives = 186/441 (42.18%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTAL 3742
            LH+A KK  I+ ++ L+K G  I   + + +TP+ +A    +++IV +L  +GA P++T+        I     L +A    + ++   L+  GA VD      +   EQT LH      K +    L+             +P  + +N         G TPLH++ + G   V   LL +     ++    G T LH+A K+    V   LL  +   + + ++  G TP H A    NQK A  +L+          N G   LH+A +    +    L+   A  N   K     TPLHLA   G   D++  L+  GANI   T      LHLA   ++V +   L ++GA          TPL +A   GNV ++  LL   +      N K +N    L    ++    I +++L H  +   +   A GNTAL
Sbjct:  402 LHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTN--------IRGETALHMAARAGQVEVVRCLLRNGALVDA-----RAREEQTPLHIASRLGKTEIVQLLLQ---------HMAHPDAATTN---------GYTPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN--GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN-GYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGV--TPLHLASQEGH-TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANV----NAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK--PNATTANGNTAL 798

HSP 3 Score: 96.6709 bits (239), Expect = 2.502e-19
Identity = 121/478 (25.31%), Postives = 209/478 (43.72%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTI-----LEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNL-GRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            LH+A   GN+     L+  G  ++  + N +TPL +A+++ N ++V++L   G   +  +    ++G   L+C    A  +    + ++L+E  A                LL RT      L M  Q  +    +       ++ K P + ++        ++  T LH+A   G   V K LL   + + N +   G T LH+A K     V+  L+  KY  ++      G TP H A  + +      +LQ    A+ ++ N+ G   LH+A +    E V  L++  A ++ R ++  + TPLH+A   G  E +++ L+   A+    T      LH++    +V + S LLE GA+ S    K  TPLH+A + G++D+ K LL   +    S    G   LH+ ++   +N  V   L+L+         K+  G T L + A K+  ++   LL  GA       +G T
Sbjct:  237 LHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKT----RDGLTPLHC----AARSGHDQVVELLLERKA---------------PLLARTKNGLSPLHMAAQGDHVECVK-----HLLQYKAPVDDVT--------LDYLTALHVAAHCGHYRVTK-LLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV--KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ--NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARARE--EQTPLHIASRLGKTE-IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGLTPLHVAAH--YDNQKVAL-LLLEKGASPHATAKN--GYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVT 664

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 139.813 bits (351), Expect = 1.588e-32
Identity = 141/503 (28.03%), Postives = 230/503 (45.73%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            + S +D       + LH+A   G  E V+ L+K G +IN +S N  TPL +A ++++ID+V+ L  +GA+ +      +++GF     PL VAL         IL+E      V + ++H     + T     +L+    A   +  +++R  ++  T         N N +  + N  +   +   N  TPLH+A + G  ++VK LL    +ID   ++  G T LH A +  H+ V+  LL  + K  L  R   G +P H A +  + +  + +LQY     D  +D L    LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +    +   LL  GA+      +GFT
Sbjct:   65 RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA----TEDGFT----PLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLL--ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYL--TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFT 544

HSP 2 Score: 112.464 bits (280), Expect = 3.493e-24
Identity = 128/526 (24.33%), Postives = 215/526 (40.87%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTAL 3742
            T D  TP H A ++ + +++ L +       K   L     G SP  +      +     + +         + +D + +D  + LH+A   G+    + L+    + N R++N  TPL +A +K+ I ++ +L   GA    +   I++ G      P+ VA      +I  +L++ GA  D+ +I       +T LH      + +    L+  G    +                     E  TPLH+A ++G   +V+ LL  +    +     G T LH++ +     V + LL      +L+ +  +G TP H A +  +   A+ +LQ    AAD     G   LH+A +    +    L+   A  N   K     TPLHLA   G   D++  L+  GANI   T      LHLA   ++V +   L ++GA          TPL +A   GNV ++  LL   +      N K +N    L    ++    I +++L H  +   +   A GNTAL
Sbjct:  275 TRDGLTPLHCAARSGHDQVVELLL-----ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQY-------KAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGA----SIQAITESGLT----PIHVAAFMGHLNIVLLLLQNGASPDVTNIR-----GETALHMAARAGQVEVVRCLLRNGALVDARAR------------------EEQTPLHIASRLGKTEIVQ-LLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK--KGFTPLHVAAKYGSLDVAKLLLQRRA-AADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGV--TPLHLASQEGH-TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANV----NAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK--PNATTANGNTAL 744

HSP 3 Score: 103.99 bits (258), Expect = 1.443e-21
Identity = 126/488 (25.82%), Postives = 218/488 (44.67%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTI-----LEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNL-GRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQ 3865
            LH+A   GN+     L+  G  ++  + N +TPL +A+++ N ++V++L   G   +  +    ++G   L+C    A  +    + ++L+E  A                LL RT      L M  Q  +    +       ++ K P + ++        ++  T LH+A   G   V K LL   + + N +   G T LH+A K     V+  L+  KY  ++      G TP H A  + +      +LQ    A+ ++ N+ G   LH+A +    E V  L++  A ++ R ++  + TPLH+A   G  E +++ L+   A+    T      LH++    +V + S LLE GA+ S    K  TPLH+A + G++D+ K LL   +    S    G   LHI +   ++N + I S +L++  E     K   G T L L + + ++ +   LL KGA++      G T   S H++ Q
Sbjct:  216 LHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKT----RDGLTPLHC----AARSGHDQVVELLLERKA---------------PLLARTKNGLSPLHMAAQGDHVECVK-----HLLQYKAPVDDVT--------LDYLTALHVAAHCGHYRVTK-LLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV--KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ--NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARARE--EQTPLHIASRLGKTE-IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGYTPLHIAA---KKNQMQIASTLLNYGAETNTVTKQ--GVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLT---SLHLAAQ 650

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 138.658 bits (348), Expect = 2.342e-32
Identity = 142/514 (27.63%), Postives = 235/514 (45.72%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIE--GNTPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF 3868
            + S +D       + LH+A   G  E V+ L+K G +IN +S N  TPL +A ++++ID+V+ L  +GA+     +  +++GF     PL VAL         IL+E      V + ++H     + T     +L+    A   +  +++R  ++  T         N N +  + N  +   +    G TPLH+A + G  ++VK LL    +ID   ++  G T LH A +  H+ V+  LL  + K  L  R   G +P H A +  + +  + +LQY     D  +D L    LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +    +   LL  GA+      +GFT     H++ ++
Sbjct:   82 RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN----QSTATEDGF----TPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLL--ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYL--TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL---HVAAKY 569

HSP 2 Score: 109.383 bits (272), Expect = 2.039e-23
Identity = 133/553 (24.05%), Postives = 224/553 (40.51%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIE---------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLG 3778
            T D  TP H A ++ + +++ L +       K   L     G SP  +      +     + +      +K + +D + +D  + LH+A   G+    + L+    + N R++N  TPL +A +K+ I ++ +L   GA    +   I++ G      P+ VA      +I  +L++ GA  D+ +I       +T LH      + +    L+  G    +    +     I++       ++               G TPLH++ + G   V   LL +     ++    G T LH+A K+    V   LL  +   + + ++  G TP H A    NQK A  +L+          N G   LH+A +    +    L+   A  N   K     TPLHLA   G   D++  L+  GANI   T      LHLA   ++V +   L ++GA          TPL +A   GNV ++  LL   +  + +K   G   LH      ++    I +++L H  +   +   A GNTAL +       RLG
Sbjct:  292 TRDGLTPLHCAARSGHDQVVELLL-----ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ------YK-APVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGA----SIQAITESGL----TPIHVAAFMGHLNIVLLLLQNGASPDVTNIR-----GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN--GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN-GYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGV--TPLHLASQEGH-TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGA-NVNAKTKNGYTPLH---QAAQQGHTHIINVLLQHGAK--PNATTANGNTALAIA-----KRLG 801

HSP 3 Score: 95.1301 bits (235), Expect = 5.049e-19
Identity = 142/602 (23.59%), Postives = 255/602 (42.36%), Query Frame = 2

Query: 2132 KGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRS---INK-----MTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENK-NP---SNSISNYESNNHYIEGNTP-----------LHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNL-GRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQ 3865
            +G  +N+  Q   +  TP ++A +  +I ++   +      N  N       G +P  + L  G     ++    L++ D K     K+ +     LH+A +K + ++   L++   + +V+S   +N+      TPL +A    N+++  +L   GA  + T+    + G      PL VA      ++  +L++ G  +D  +   +D    T LH       +Q    L+ R    ++  +N  +P   +    + E   H ++   P           LH+A   G   V K LL   + + N +   G T LH+A K     V+  L+  KY  ++      G TP H A  + +      +LQ    A+ ++ N+ G   LH+A +    E V  L++  A ++ R ++  + TPLH+A   G  E +++ L+   A+    T      LH++    +V + S LLE GA+ S    K  TPLH+A + G++D+ K LL        S    G   LH+ ++   +    +  L+L+         K+  G T L + A K+  ++   LL  GA       +G T     H++ Q
Sbjct:  115 EGANINAQSQ---NGFTPLYMAAQENHIDVVKYLL-----ENGANQSTATEDGFTPLAVALQQG----HNQAVAILLENDTK----GKVRLPA---LHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTA----RNGI----TPLHVASKRGNTNMVKLLLDRGGQIDAKT---RDGL--TPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTK-LLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV--KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQN--GASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARARE--EQTPLHIASRLGKTE-IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAK-LLLQRRAAADSAGKNGLTPLHVAAHYDNQK---VALLLLEKGASPHATAKN--GYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPL---HLASQ 667

HSP 4 Score: 52.373 bits (124), Expect = 5.665e-6
Identity = 45/174 (25.86%), Postives = 81/174 (46.55%), Query Frame = 2

Query: 2078 LALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITS 2599
            L +  K+N+  + +T    G + N+   +T    TP HLA +  +  ++ L +  D+G    N  M+  +G +   L      ++V D + +     D  T      +I       +A   GN++ V FL+K G ++N ++ N  TPL  A ++ +  I+ +L   GA PN T+
Sbjct:  629 LHIAAKKNQMQIASTLLNYGAETNT---VTKQGVTPLHLASQEGHTDMVTLLL--DKG---ANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLI-------VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATT 787

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. UniProt/SwissProt
Match: sp|Q810B6|ANFY1_MOUSE (Rabankyrin-5 OS=Mus musculus OX=10090 GN=Ankfy1 PE=1 SV=2)

HSP 1 Score: 443.351 bits (1139), Expect = 5.940e-133
Identity = 256/652 (39.26%), Postives = 370/652 (56.75%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +I L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA +     +V  +C  GAD ++      ++G    N PLW+AL +   DIA  LV  G D   W         QTLLHR + E  E  A FLI  GCD  S      P    +N E      +G TPLH+A   GLE  V+ LL     +VN Q+A G T +H+A+  +H +V+  LL     + LS+RD QG TPF  AM   N KAA +IL+    AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ LHIL    +EN   IF L L+  PE+P+D+ DA GNT L L  +K N+ L  A++  G  LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC +CF+ L  G
Sbjct:  540 SIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMSVPD----EKG----NPPLWLALASNLEDIASTLVRHGCDATCWGPG-PSGCLQTLLHRAVDENNESTACFLIRSGCDVNS------PRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGA-NVNAQDAEGRTPVHVAISNQH-SVIIQLLISHPNIELSVRDRQGLTPFACAMTYKNNKAAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRALLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRSGVRLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1166

HSP 2 Score: 230.72 bits (587), Expect = 3.854e-60
Identity = 287/1103 (26.02%), Postives = 475/1103 (43.06%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQG----ITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNA-----NRGLLMDLALGKKQNKEILKTT-----HRCKGRKVNSDKQL---TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQS--LLHLAVKKGNIEAVQFLIKIGCDINVRSINK----MTPLLLATEKSNIDIVRILCLSGADPNIT----SNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIS--------------TMENKNPSNSISNYESNNHYI---EGNTPLHMACQ-MGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAAR---SILQYHPQAADEIDNLGRNFLHVAV 3232
            L KH  LL+QEY K+  K    + +   L   +   ++ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ EEI+L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  L A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A   P    A+ ++ +  I   L+Q GA+                 NM  +   RT L L+I++ N+ V   +L   +C  ++        + K    S               LWLA+      +++ +  D       + +P       E  P V   S   NS    ++ +G    A  V+      Q++            ATS   +  N  N + E+  H A  + L NL   LLQ GA+PN+     +                       + K+S +     + IY QT                    P   +M I  +  H   +S+ + +K+NA     N  ++ D +L   +++ +L        H    + + S   +     D  T  H+A++ ++ K   LF+   E +  +N    D  GE+   L + + L  V D I  R           D  V DE+    L LA+     +    L++ GCD             T L  A +++N      L  SG D N      +N   +E   +   PL +A +    +    L+E GA+V+      +D   +T +H  I          LIS     +S              T +N   + +I   ES        +G   LH+A Q   +ESV+  +     ++  VQ+A+  T LHLAV+   E ++ +LL    K+N   +  Q      TA+ L+ Q+      S+L  +      +D  G N LH+AV
Sbjct:    9 LEKHLMLLRQEYVKLQKKLAETEKRCTLLAAQANKENSNESFISRLLAIVAGLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTEEIDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSLSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSHKADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGANP----------------NMQ-DSKGRTPLHLSIMARNDCVFSQLL---QCKQLD-------LELKDHEGST-------------ALWLAV------QYITVSSD------QSVNPF------EDLPVVNGTSFDENSFAARLIQRGSNTDAPDVMTGNCLLQRAAGAGNEAAALFLATSGAHA--NHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALP----------------------VPKESPVLMSSADSIYLQT--------------------PL--HMAIAYN--HPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSA-LFLL--EHQADINVRTQD--GETALQLAIKHQLPLVVDAICTR---------GADMSVPDEKGNPPLWLALASNLEDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNA-----QDAEGRTPVHVAISNQHSVIIQLLISHPNIELSVRDRQGLTPFACAMTYKNNKAAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQ------TALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 980

HSP 3 Score: 75.8702 bits (185), Expect = 2.667e-12
Identity = 140/663 (21.12%), Postives = 245/663 (36.95%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSIN-KMTPL----LLATEKSNID-------IVRILCLSGADPNITS---------NIISQEGFI-----------------ELNCPLWVA--------------------LNNCRFD---IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGC-------------------TSLHLAVKFRHEAVLTHLLNPKYKL-----------NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKD---AFQYT----------------------------PLHLAIISGAPEDLIRSLILAGANIA----NETIEKQNLLHLAVIHERVYIISFLLENG------------ASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCAL 3757
            P H A+K +   ++ L++   + +        D+ G+    L L   L S+   +           +++D +  +  SLLH  +++G++ A  FLIK G  +N  +   + TPL    L + +K + D       I   L  +GA+PN+           +I+++   +                 E +  LW+A                    +N   FD    A  L++ G++ D   +   +     LL R      E AA FL + G                    +N+    G TPLH AC+ GL ++   LL     + N+Q                        T LH+A+ + H  V++ +L  K              + S++D +  T    A+       A  +L       D + + G+  LH+A+Q  + ++  FL++  A++N+R +D   A Q                              PL LA+ S   ED+  +L+  G +        +   Q LLH AV         FL+ +G                 +    +TPLHLA   G  + ++ LL      + +++ +G   +H+  +N      VI  L++ H P   +  +D  G T  F CA+
Sbjct:  221 PLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSH-------KADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHLSIMARNDCVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDLPVVNGTSFDENSFAARLIQRGSNTDAPDVMTGN----CLLQRAAGAGNEAAALFLATSGA------------------HANHRNKWGETPLHTACRHGLANLTAELLQQGA-NPNLQTEEALPVPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSD-GQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMSVPDEKGNPPLWLALASNL-EDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLL-EFGANVNAQDAEGRTPVHVAISNQHS---VIIQLLISH-PNIELSVRDRQGLTP-FACAM 845

HSP 4 Score: 56.6102 bits (135), Expect = 2.003e-6
Identity = 111/452 (24.56%), Postives = 176/452 (38.94%), Query Frame = 2

Query: 2675 IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC---------------------------DTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGAN-------------------IANETIEKQNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            IA  LV   ADVDM      D    +LLH+ I      A+ FLI  G                            D +S M     +   +    N    +G TPLH++     + V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I +     A ++   G   L  A    N  A  FL    A+ N R K  +  TPLH A   G   +L   L+  GAN                    + ++I  Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+K    L V A+  +GA +   + +G
Sbjct:  271 IATTLVSHKADVDM-----VDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHLSIMARNDCVFSQLLQCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFEDLPVVNGTSFD-ENSFAARLIQRGSNTDAPDVMT-GNCLLQRAAGAGNEAAALFLATSGAHANHRNK--WGETPLHTACRHGLA-NLTAELLQQGANPNLQTEEALPVPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTQD--GETALQL-AIKHQLPLVVDAICTRGADMSVPDEKG 688

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. UniProt/SwissProt
Match: sp|Q9P2R3|ANFY1_HUMAN (Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2)

HSP 1 Score: 440.269 bits (1131), Expect = 9.093e-132
Identity = 253/652 (38.80%), Postives = 370/652 (56.75%), Query Frame = 2

Query: 2165 TIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            ++ L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA       +V  +C  GAD ++      ++G    N PLW+AL N   DIA  LV  G D   W         QTLLHR I E  E  A FLI  GCD  S      P    +N E      +G TPLH+A   GLE  V+ LL     +VN Q+A G T +H+A+  +H  V+  LL     ++L++RD QG TPF  AM   N K+A +IL+    AA+++DN GRNFLHVAVQ  + E+V FLI V+AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ LHIL    +EN   IF L L+  P +P+D+ DA G+T L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  +F +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC +CF+ L  G
Sbjct:  540 SVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPD----EKG----NPPLWLALANNLEDIASTLVRHGCDATCWGPG-PGGCLQTLLHRAIDENNEPTACFLIRSGCDVNS------PRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGA-NVNAQDAEGRTPIHVAISSQH-GVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1166

HSP 2 Score: 234.572 bits (597), Expect = 2.409e-61
Identity = 285/1106 (25.77%), Postives = 481/1106 (43.49%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKD-----FNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNA-----NRGLLMDLALGKKQNKEILKTT-----HRCKGRKVNSDKQL---TIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQS--LLHLAVKKGNIEAVQFLIKIGCDINVRSINK----MTPLLLATEKSNIDIVRILCLSGADPNIT----SNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWS------IHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIS---TMENKNPSNSISNYESNNHYI---EGNTPLHMACQ-MGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAAR---SILQYHPQAADEIDNLGRNFLHVAV 3232
            L KH  LL+QEY K+  K    + +   L   +   S+ ++F   L  IV  LY+ +++SD+ IK+    I  H+ +  A    W+ ++LS+ +E++L +    +   +++WIY  EL   ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N    + +L LDLALS +   +  TL+   A+++ VD  GWSLLHK IQR D F+  FLI+NG  +N  +    +TP+ L+A        A+ ++ +  I   L+Q GA+                 NM  +   RT L ++I++GNE V   +L   +C  ++        + K    S               LWLA+      +H+ +  D     F D V +    +F        LI+  +      D+ TGN ++      G E AA+F+  A N                     VN  N + E+  H A  + L NL   LLQ GA+PN+     +                       L K++     + + ++ QT                    P   +M I  +  H   +S+ + +K+NA     N  ++ D +L   +++ +L        H    + + S   +     D  T  H+A++ ++ K   LF+   E +  +N    D  GE+   L + N L  V D I  R           D  V DE+    L LA+     +    L++ GCD             T L  A +++N      L  SG D N      +N   +E   +   PL +A +    +    L+E GA+V+         IH   + +  ++ + ++   +   N    +G    +   T +N   + +I   ES        +G   LH+A Q   +ESV+  +     ++  VQ+A+  T LHLAV+   E ++ +LL    K+N   +  Q      TA+ L+ Q+      S+L  +      +D  G N LH+AV
Sbjct:    9 LEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP----------------NMQ-DSKGRTPLHVSIMAGNEYVFSQLL---QCKQLD-------LELKDHEGST-------------ALWLAV------QHITVSSDQSVNPFED-VPVVNGTSFDENSFAARLIQRGSHTDA-PDTATGNCLLQRAAGAGNEAAALFL--ATNGAH------------------VNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALP----------------------LPKEAASLTSLADSVHLQT--------------------PL--HMAIAYN--HPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSA-LFLL--EHQADINVRTQD--GETALQLAIRNQLPLVVDAICTR---------GADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQ------TALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV 980

HSP 3 Score: 71.2478 bits (173), Expect = 6.219e-11
Identity = 98/430 (22.79%), Postives = 174/430 (40.47%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNI-----------TSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNI------------RVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N R+    TPL  A      ++   L   GA+PN+            +++ S    + L  PL +A+     D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA++ +   V+  +       ++S+ D +G+ P   A+  + +  A +++++   A       G   +  LH A+   N     FLI+   ++N               +D    TPLHLA   G  E+ ++ L+  GAN+  +  E +  +H+A+  +   II  L+ +     + +D +  TP   A+   N    + +L   S   +  + KG N LH+   N
Sbjct:  476 FLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICT--RGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDG--QTPLHLAASWGL-EETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQN 881

HSP 4 Score: 64.6994 bits (156), Expect = 6.699e-9
Identity = 118/462 (25.54%), Postives = 184/462 (39.83%), Query Frame = 2

Query: 2648 VALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQ-YHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK-------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            +AL+     IA  LV   ADVDM      D    +LLH+ I      AA FLI  G   +  +    + P + ++ Y S  H  +                         G TPLH++   G E V   LL   ++D+ +++  G T+L LAV+                 ++++   Q   PF        T+ +  N  AAR I +  H  A D     G   L  A    N  A  FL    A++N R K  +  TPLH A   G   +L   L+  GAN   +T E                    Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S   I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+++   L V A+  +GA +   + +G
Sbjct:  262 LALSRRLESIATTLVSHKADVDM-----VDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQ-----------------HITVSSDQSVNPFEDVPVVNGTSFD-ENSFAARLIQRGSHTDAPDTAT--GNCLLQRAAGAGNEAAALFLATNGAHVNHRNK--WGETPLHTACRHGLA-NLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTG-MHTIAAQLLGSGAAINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTQD--GETALQL-AIRNQLPLVVDAICTRGADMSVPDEKG 688

HSP 5 Score: 56.225 bits (134), Expect = 2.626e-6
Identity = 57/210 (27.14%), Postives = 90/210 (42.86%), Query Frame = 2

Query: 3011 LHLAVKF-RHEAVLTHLLNPKYKL--NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLA-VIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENIL 3628
            LH A+K  R + V  +L+    +L   L+  DH G      A+    +  A +++  H    D +D  G + LH  +Q  +  A  FLI+  A +N     A Q TPLHL  +  + +                        H A V+ E   I   LL+ GA+ + QD+K  TPLH+++  GN  +   LL      ++ K+ +G   L
Sbjct:  222 LHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVS-HKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGA-QETPLHLVALYSSKK------------------------HSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTAL 405

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. UniProt/SwissProt
Match: sp|Q8C8R3|ANK2_MOUSE (Ankyrin-2 OS=Mus musculus OX=10090 GN=Ank2 PE=1 SV=2)

HSP 1 Score: 140.584 bits (353), Expect = 7.794e-32
Identity = 141/503 (28.03%), Postives = 230/503 (45.73%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            + S +D       + LH+A   G  E V+ L+K G +IN +S N  TPL +A ++++ID+V+ L  +GA+ +      +++GF     PL VAL         IL+E      V + ++H     + T     +L+    A   +  +++R  ++  T         N N +  + N  +   +   N  TPLH+A + G  ++VK LL    +ID   ++  G T LH A +  H+ V+  LL  + K  L  R   G +P H A +  + +  + +LQY     D  +D L    LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +    +   LL  GA+      +GFT
Sbjct:   86 RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA----TEDGFT----PLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLL--ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYL--TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFT 565

HSP 2 Score: 109.383 bits (272), Expect = 2.417e-22
Identity = 118/441 (26.76%), Postives = 187/441 (42.40%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTAL 3742
            LH+A KK  I+ ++ L+K G  I   + + +TP+ +A    +++IV +L  +GA P++T+        I     L +A    + ++   L+  GA VD      +   EQT LH      K +    L+             +P  + +N         G TPLH++ + G   V   LL +     ++    G T LH+A K+    V   LL  +   + + ++  G TP H A    NQK A  +L+          N G   LH+A +    +    L+   A  N   K     TPLHLA   G   D++  L+  GANI   T      LHLA   ++V +   L ++GA          TPL +A   GNV ++  LL   +  + +K   G   LH      ++    I +++L H  +   +   A GNTAL
Sbjct:  402 LHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTN--------IRGETALHMAARAGQVEVVRCLLRNGALVDA-----RAREEQTPLHIASRLGKTEIVQLLLQ---------HMAHPDAATTN---------GYTPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN--GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN-GYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGV--TPLHLASQEGH-TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGA-NVNAKTKNGYTPLH---QAAQQGHTHIINVLLQHGAK--PNATTANGNTAL 798

HSP 3 Score: 96.6709 bits (239), Expect = 1.416e-18
Identity = 121/478 (25.31%), Postives = 209/478 (43.72%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTI-----LEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNL-GRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            LH+A   GN+     L+  G  ++  + N +TPL +A+++ N ++V++L   G   +  +    ++G   L+C    A  +    + ++L+E  A                LL RT      L M  Q  +    +       ++ K P + ++        ++  T LH+A   G   V K LL   + + N +   G T LH+A K     V+  L+  KY  ++      G TP H A  + +      +LQ    A+ ++ N+ G   LH+A +    E V  L++  A ++ R ++  + TPLH+A   G  E +++ L+   A+    T      LH++    +V + S LLE GA+ S    K  TPLH+A + G++D+ K LL   +    S    G   LH+ ++   +N  V   L+L+         K+  G T L + A K+  ++   LL  GA       +G T
Sbjct:  237 LHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKT----RDGLTPLHC----AARSGHDQVVELLLERKA---------------PLLARTKNGLSPLHMAAQGDHVECVK-----HLLQYKAPVDDVT--------LDYLTALHVAAHCGHYRVTK-LLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV--KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ--NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARARE--EQTPLHIASRLGKTE-IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGLTPLHVAAH--YDNQKVAL-LLLEKGASPHATAKN--GYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVT 664

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. UniProt/SwissProt
Match: sp|Q01484|ANK2_HUMAN (Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4)

HSP 1 Score: 136.732 bits (343), Expect = 1.060e-30
Identity = 138/502 (27.49%), Postives = 228/502 (45.42%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            + S +D       + LH+A   G  E V+ L+K G +IN +S N  TPL +A ++++ID+V+ L  +GA+ +      +++GF     PL VAL         IL+E      V + ++H     + T     +L+    A   +  +++R  ++  T         N N +  + N  +   +   N  TPLH+A + G  ++VK LL    +ID   ++  G T LH A +  H+ V+  LL  +    L  R   G +P H A +  + +  + +LQ H    D++       LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +    +   LL  GA+      +GFT
Sbjct:   86 RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTA----TEDGFT----PLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD--GLTPLHCAARSGHDQVVELLL--ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ-HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRIK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA-LVDARAREEQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFT 565

HSP 2 Score: 112.079 bits (279), Expect = 3.261e-23
Identity = 119/441 (26.98%), Postives = 187/441 (42.40%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTAL 3742
            LH+A KK  I+ ++ L+K G  I   + + +TP+ +A    +++IV +L  +GA P++T+        I     L +A    + ++   L+  GA VD      +   EQT LH      K +    L+             +P  + +N         G TPLH++ + G   V   LL +     ++    G T LH+A K+    V   LL  +   + + ++  G TP H A    NQK A  +L+          N G   LH+A +    +    L+   A  NI  K     TPLHLA   G   D++  L+  GANI   T      LHLA   ++V +   L ++GA          TPL +A   GNV ++  LL   +      N K +N    L    ++    I +++L H  +   +   A GNTAL
Sbjct:  402 LHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTN--------IRGETALHMAARAGQVEVVRCLLRNGALVDA-----RAREEQTPLHIASRLGKTEIVQLLLQ---------HMAHPDAATTN---------GYTPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN--GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN-GYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGV--TPLHLASQEGH-TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANV----NAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK--PNATTANGNTAL 798

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. UniProt/SwissProt
Match: sp|O70511|ANK3_RAT (Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE=1 SV=3)

HSP 1 Score: 124.405 bits (311), Expect = 5.210e-27
Identity = 145/556 (26.08%), Postives = 250/556 (44.96%), Query Frame = 2

Query: 2306 LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLSSN-KIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILA---GANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLLDSLSSEPN 3907
            L    G + V  ++ +R    D  T + +       + LH+A   G  E V+ L+  G ++N +S N  TPL +A +++++++VR L  +GA    + ++ +++GF     PL VAL      +  +L+E      V + ++H     + T     +L+    A   +  +++R  ++  T         N N +  + N  +   +   N  TPLH+A + G  ++VK LL    KID   ++  G T LH   +  HE V+  LL+    + LS +   G +P H A +  +    + +LQ H    D++ N     LHVA    + +    L+   AN N +  + F  TPLH+A      ++ IR + L    GA+I   T      +H+A     V I+S L+ +GAS +  + + ET LH+A R G  ++++  L      +++K    +  LHI S    +  IV   L     P    +     G T L L A + +  +   LL  GASL     +GFT     H++ ++    +  LL   S+ P+
Sbjct:   80 LASKEGHVEVVSELLQREANVDAATKKGN-------TALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGA----SQSLATEDGF----TPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADIESKMVVNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPI-LS-KTKNGLSPLHMATQGDHLNCVQLLLQ-HNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF--TPLHIACK----KNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHI-SARLGKADIVQQLLQQGASP----NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPL---HVAAKYGKLEVASLLLQKSASPD 600

HSP 2 Score: 112.079 bits (279), Expect = 2.781e-23
Identity = 149/604 (24.67%), Postives = 258/604 (42.72%), Query Frame = 2

Query: 2135 GRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRS---INK-----MTPLLLATEKSNIDIVRILCLSGADPNITS-NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENK-NP-----------------SNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQ 3865
            G  VN+  Q   +  TP ++A +  +++++   +      N  +  +    G +P  + L  G     D++   L++ D K     K+ +     LH+A +K + +A   L++   + ++ S   +N+      TPL +A    NI++  +L    A  + T+ N I+         PL VA      ++  +L++ GA +D  +   +D    T LH       EQ    L+ R    +S  +N  +P                  +++   +  N Y+   T LH+A   G   V K LL   K + N +   G T LH+A K     V+  LL  K+  ++      G TP H A  + +     S L +H  + +  +  G   LH+A ++   E V +L+Q  A +  + KD    TPLH++   G   D+++ L+  GA+    T      LHL+       + +FLL++GAS S    K  TPLH+A + G +++   LL   S +  +    G   LH+ ++   +N  V   L+LD         K+  G T L + A K+   +  +LL  GA       +G     S H++ Q
Sbjct:  130 GANVNAQSQ---NGFTPLYMAAQENHLEVVRFLL-----DNGASQSLATEDGFTPLAVALQQG----HDQVVSLLLENDTK----GKVRL---PALHIAARKDDTKAAALLLQNDTNADIESKMVVNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDIT---------PLHVASKRGNANMVKLLLDRGAKIDAKT---RDGL--TPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYL---TALHVAAHCGHYKVAKVLLD-KKANPNAKALNGFTPLHIACKKNRIRVMELLL--KHGASIQAVTESGLTPIHVAAFMGHVNIV-SQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKD--DQTPLHISARLGK-ADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVAS-LLLQKSASPDAAGKSGLTPLHVAAH--YDNQKVAL-LLLDQGASPHAAAKN--GYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIA---SVHLAAQ 681

HSP 3 Score: 105.916 bits (263), Expect = 2.036e-21
Identity = 128/543 (23.57%), Postives = 215/543 (39.59%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTS--------------------------EIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGAN--------IANETIEKQ-----------------NL--------LHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILH 3631
            TP H+A K  N  ++ L +  D G  K++    D  G +P      +G   V + + +R      KT                            +D +  D  + LH+A   G+ +  + L+    + N +++N  TPL +A +K+ I ++ +L   GA    +   +++ G      P+ VA      +I   L+  GA  +  ++       +T LH      + +   +L+  G    +  ++                    TPLH++ ++G   +V+ LL       N    +G T LHL+ +  HE V   LL+  +  +LSI   +G TP H A +    + A  +LQ    + D     G   LHVA    N++    L+   A+ +   K+   YTPLH+A       D+  SL+  GA+        IA+  +  Q                 NL        LHLA   +RV +   L+  GA    Q     TPLH+    GN+ ++  LL +S+  + +K   G   LH
Sbjct:  278 TPLHVASKRGNANMVKLLL--DRG-AKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHGA----SIQAVTESGL----TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG-----ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ------------------TPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLSAREGHEDVAAFLLD--HGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKS-ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNG--YTPLHIAAKKNQ-MDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA-KVNAKTKNGYTPLH 776

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. TrEMBL
Match: A0A3Q0KLX9 (Ankyrin repeat and fyve domain containing,putative OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 536.184 bits (1380), Expect = 5.240e-164
Identity = 415/1360 (30.51%), Postives = 662/1360 (48.68%), Query Frame = 2

Query:   98 EYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSV---DNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTA-LCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTF--MLIENEADPGV--------------LYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLC-RLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNANRGLLMDLALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIE-GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFN------SEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVN 4093
            EY K+ ++ + L+ + + L    G+   E NF  N+   V  L+ + K+SD+  K     +PGH+ + +A G  WN       E IN++   QN+ E  + W Y   L + +  + L  LM +A E  L  L  +CE   I  VS++NC+  Y  +       L   C   I   W  +   +   + A +    LE  S +P+H A++  RDD V   +N ++ + + LVN ++E+    L +AL     EL E L+   A++N++    +    +   A +++   + +FL+  G + +      S+T +  LA +  + E +EA+                                IN+A     R+A +    + GN  +  ++L +      +G+ +   + +K K N  +P           PLWLA+ R++      I   F      + S  F   LIEN A+                 L +   G+++++     G E AA+F+LN          +    T  SFT+          E+VFHVAVE+EL NLC RL+++   DPN +R   +    S+ +                            EI  QT  +S+    ++  + T  +NPF +  +  NDD + LS  +  I     +  L  DLA+                    +  K      C+P HLAV+ K   +  +F F+ E +  V+WL+ + +G+S  +L LW+    +  +I E +      TS      I+E            I++   +I   C       NK + L+ + E+   ++V+ L    AD  I  N    + +I    PLW AL   R+ IAD LV  GADV+ W+   + N + TLLHR I E  E+A  FL+ R CD  +  +      S+   +S++   E   +PLHMA  +G+  +V+ L+SSN++ +N Q+  G T+LHLA++ ++E  L +LL    +++ ++RD Q +T FH A++L  +  A+++L+  P  A ++D+ GRNFLH A++  +REA++ LIQ+  ++N  V+D  + TP HLAI +G  ED++RSL+LAGA+I ++T +KQ  LHLAVI+ R  ++  LLENGA  + QD++  TPLHLAVR   VD +  +L + ST     N++G+  +H+L+ +     + +   +L+      ++ +DA GNT L L    +N  L  ALL  GASLG  N EG T+F+            + + +LLDSL  EP W DG +C  C  KF I NRKHHCRHCGRL+C +CS  E+PI+K+ + KPVRVCEVCFNFL N
Sbjct:   13 EYQKLRDRVEKLEKENEMLTTELGH--REQNFCGNILAFVEGLFLNTKYSDVLFKTPNVLVPGHKFVLDARGGVWNVYTKDGVEYINIQGYCQNVCEAFIHWAYRGILEEYEA-QCLSDLMTLAREFCLPSLFTQCEIALIPLVSRENCLSLYSSSYRLRATRLLDHCFLFISGVWPNFSVEEISTVSAPVLQSFLEKYSKFPVHSAIELGRDDTVLSLLNVDHPKAKLLVNQLNENGLSPLYMALKDAHFELAEKLIGLGADINALIGSTDEKQPVTQFAFRKRQYEAVQFLLLRGSNCDFCDSISSRTLLHNLA-VTDAQEVSEAV--------------------------------INIAKTLIKRSANISSQDIDGNSPLHLSILHNN-----SGLFNLLINHSK-KPNLDLPNNQGLC-----PLWLALVRKFNFRDSSIC-GFESNSLTSNSYDFASQLIENGANVNYRFTDVQYYALNSKSLKNPLPGDTLLLAASRIGWESAALFLLNC---------SQCDPTLESFTQG---------ETVFHVAVESELSNLCNRLIMRNDTDPNRLRFSKVNIITSDGE----------------------------EILSQTSYESTCVKETNQRNFTKSLNPFDDDYE-SNDDCYLLSNPMDNISNQVNSSRLFTDLAVNGAATSTTSVLDSSSLSVIKSYHKSTQQIYCSPLHLAVQHK---MFGIFEFYLENKANVDWLLLNESGDSVLSLLLWSEQFQLVKRILESMYNQSKNTSASPDFKINE--------SDNTIQSFLSIIPTKC-------NKPSLLIQSIERDQFEVVKFLVEHDAD--INENETDSQLYIN---PLWTALKLRRWKIADYLVNHGADVNSWAPFNETNAKITLLHRAIHENNEEAGVFLVKRNCDVNACAQF---DYSVDKKKSDHIIPELARSPLHMATLIGMCELVEVLISSNRVYINQQDYNGETALHLAIRSKNEK-LANLLIEAPQIDYTVRDAQAYTVFHVAVDLRQRTIAQNLLKKDPSLALQVDSSGRNFLHTAIENFDREAIFLLIQIGVDMNACVRDVHRLTPFHLAIKTGVDEDILRSLLLAGASINSQTPQKQYGLHLAVIYNRPELVHCLLENGADPNAQDSERNTPLHLAVRHARVDCLVKMLNHPSTNCYCINIRGQLPIHLLAQHQGPVSVEMLEYLLEISVANQINAQDAAGNTPLILAYQAENISLCTALLQAGASLGILNYEGDTVFSLNKKKYKSSTPGRVLSQLLDSLIQEPRWEDGSVCIECGVKFGITNRKHHCRHCGRLLCAQCSAFEVPIVKYELSKPVRVCEVCFNFLNN 1250

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. TrEMBL
Match: A0A4S2LAB3 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_008617 PE=4 SV=1)

HSP 1 Score: 522.702 bits (1345), Expect = 1.013e-158
Identity = 416/1380 (30.14%), Postives = 655/1380 (47.46%), Query Frame = 2

Query:   86 LLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSV--DNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFR-----TALCLAILSGNEIVMKAVLDSGRCNSINGVNS------WCTSKTK-SKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCR-LLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSL-PMIRKSNANRGLLMDLALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKI-------FERLIKTDFKTSEIDKIVID------EQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIST-----MENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEF----PVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHI------SEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVN 4093
             L  E +++  +   L+   +N +L++        F  N+ + V++L  ++K SDI ++     +PGH+ +  A G +W      +     +E+  Q   E ++ W+Y  EL    + + L +L+ +A +H L  L ++CE      + +DNC+  Y+ A       L   C +L+ + W+     + + L     L LLE ++ +PLH +++  RDDV  L + EN   +  LVNV+ ++    L L+L  K+ +L E LL++ A L+ V  +N      H A+   +  + +FLI +G  ++ L    + T +  L    P  ED +    +    +LL + G                       N F       T L +A+L  N  +   +++  +   +N  N+      W            A+  A  F    P P   +  +      +    D N + A +   + + ++   D  +    E G++++I     GL+ AA+F+L     +Q + L N    A               E+VFHVA+E++L +LC  L     ADPN +R +     +  ++       +  H ++  KK        ++E + Q                     P  E   +   D  SLS  L P     N N   + ++ L K  +  + +T   C+     ++K+      TP HLA+     ++I L++   + + + +WL+ D  G+S F+L LWN    + ++I       +++           +  V+         SLL  AV++  +EAV+FL++   D N       TP       SN+D+   L         + N+   +  +   CPLW +L   R +IA +LV  GADVD W+       + TLLHR I    E A  FLI  GCD  +T     M   + SN    +      ++   PLHMA   GL    + LL   + DVN Q+  G T++HLAV+  H  ++  LL     L+  +++  GHT FH AME  N KAA+S+L      A + DNLGRNFLH+A+Q ++R AV+FLIQ   NLN  V D+ QYTPLHLAII+G PED+ RSL+LAGA+I++ T +K   LHL ++H R  +++ L+ENGA  + QD++M TPLHLAVR  N+  +  LLA   T     N++G+  +H+L+    E+   I   IL H  E      ++ KDA GNT L L     N  L +AL+  GASLG  N +G ++F+   +       ++ ++++LDSL  EP W DG  C  C  KF +  RKHHCRHCGRL+C +CS  E+PIIKF I KPVRVCE CF FL N
Sbjct:    7 FLTTELNRLTRRVNELQK--ENSVLMAALGKRSHTFCSNIIEFVKTLQGNEKLSDILVQTADKVLPGHQFVIGARGGKWEFVRDGDHTVTKIESNNQAACEALLSWLYTGELLPTDDAKALSELIVLARKHELTELVSQCEMMLSFLLRRDNCVLLYEAAFVSKALVLLEHCFSLLSSAWDCISKDELNTLSPKALLSLLEKKTRFPLHCSIEFERDDVALLILEENPVDVRTLVNVLDDNGLSPLYLSLKYKQFDLAEYLLQNGALLDLVIGENERMPTAHYALMHNELETVQFLIGHGFQVDSLMEPANSTLLHALCQKSP--EDKKHSEHLGLARSLLSKEG-----------------------NAFIADASGNTPLHVALLHCNTSMFGLLMEHVKGADLNAANNMGFPLLWLALVADFGFEQKALLDAIGFSRSCPSPQSCSFSKTL----VHAGADVNHQFARSVKESAIRVDAVPDTNL---PEAGDTLLIACARCGLDAAALFLL-----QQPACLVNAESAAVP------------GETVFHVAIESKLTSLCHSLATSYQADPNRLRIKEFGCTSFPTEPSSPRQPNPPHRFTETKKLEPFDLFPDDEEFLQHPT-----------------RPVNEDQFVTPFDAESLSERLDPDGEGQNLN---VSEVTLEKATS--VQQTGAPCR----RTEKR------TPLHLAMARGMTQLIELYL-DQKAKCEPDWLLQDETGDSVFSLALWNAQFDLANRILIAASRQYQQHAVQPLPNGSTNNTVMQFDCQGTGPSLLQRAVERDQLEAVRFLLRHRVDANNSFGLSGTP-----PTSNLDVEYRLS--------SVNLTPADSIV---CPLWSSLLRNRPNIAQLLVSHGADVDYWTEFVGTPVQVTLLHRAIDCRLESATEFLIKNGCDVNATPRYPQMFKTHTSNL--GFLDTVQPLKAWHPLHMASANGLLETARCLLRCGRADVNRQDIDGNTAVHLAVRAGHNGLVEVLLQCPV-LDCGVKNSLGHTAFHVAMECRNVKAAQSLLSRDSTLALQTDNLGRNFLHIALQNVDRAAVFFLIQTGMNLNQCVNDSTQYTPLHLAIIAGVPEDVFRSLLLAGASISSRTPQKHTPLHLCILHNRPELLNCLIENGAEVNEQDSEMNTPLHLAVRNANIPCLTILLAQPQTDCCIMNIRGQLPIHLLA----EHNSAIAVEILQHLFEICVTPQINSKDAAGNTPLLLAYRSGNVPLCIALVHAGASLGLTNADGHSVFSLSRLRKRSASPDRILMQILDSLMQEPLWEDGPSCVECQAKFGLTYRKHHCRHCGRLLCAQCSNFEVPIIKFGINKPVRVCETCFEFLNN 1279

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. TrEMBL
Match: A0A1L8H8C4 (Uncharacterized protein OS=Xenopus laevis OX=8355 GN=XELAEV_18015397mg PE=1 SV=1)

HSP 1 Score: 465.692 bits (1197), Expect = 9.898e-139
Identity = 272/692 (39.31%), Postives = 398/692 (57.51%), Query Frame = 2

Query: 2048 SNANRGLLMDLALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLN-PKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            SN    LL   A    Q +E + +T   +G   NS  + T  L TP H+A+   +  ++++ +       H+    ++  ++ + D + ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DINVR+ +  T L LA +     +V  +C  GAD ++T     ++G    N PLW+AL N + DIA  LV  G D   W        +QTLLHR I E KEQ A F+I  GCD  ST   + P     N E      +G TPLH+A   GLE VV+ LL     +VN Q+A G T +H+A+  +H  ++  L++ P  +LN  +RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+D  + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   S  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ +HIL    +EN   IF L L+  PE+P+D+ DA GNT L L  +K N+ L  A++  GA LG  N++G  +FN +  ++Q + +LLD LS EP W DG  C+ C+ KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  504 SNLTAELLQQGANPNIQTEEPIAST---RGSPANSPAESTY-LQTPLHMAIAYNHPDVVSVILEQKANALHETNNLQIIPDFSLKDSSEQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICTRGADMSVTD----EQG----NPPLWLALENEQEDIASTLVRHGCDATFWGPG-PSGCQQTLLHRAIDENKEQIACFIIRSGCDVNST---RKPG---PNGEGEEEARDGQTPLHLAASWGLEEVVQCLLEFGA-NVNAQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLN--VRDRQGMTPFRCAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDVSKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPVICSVLLENGVDFSAADENGNNALHLAVMHGRLNNIRCLLTECNVDAEALNLRGQSPMHILGQYGKENAAAIFELFLECMPEYPLDKPDAEGNTVLLLAYIKGNANLCRAIVKAGARLGVNNSQGINIFNYQVATKQLLFRLLDMLSQEPPWCDGSNCYECVAKFGVTTRKHHCRHCGRLLCAKCSTKEIPIIKFDLNKPVRVCDICFDVLTLG 1165

HSP 2 Score: 210.69 bits (535), Expect = 2.354e-51
Identity = 112/324 (34.57%), Postives = 194/324 (59.88%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLAN 1039
            L KH  LL+QEY K+  K    + K   L   +   ++ D+F   L  IV  L++ +++SD+ IK+    I  H+ +  A    W+ ++L++ +E++L +    +   +++WIY  EL+  ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E     L ++C+ +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  SQL   +N + ++ +L LDLALS +   +  TL+ S A+++ +D  G SLLHKAI R D+F+  FLI+NG  +N  +    QTP+ L+A+
Sbjct:    9 LQKHLALLRQEYVKLQQKLAETEKKCTLLAAQANKEASNDSFISRLLSIVAQLFEQEQYSDLKIKVGDKHINAHKFVLAARSEVWSPTNLASTKELDLSDSNPEVTMAMLRWIYTDELDLREDDIFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELDASALLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTQFPLHKAIKLEREDVVFLYLIEMDSQLPGKLNELDQNGDLSLDLALSRRLESIATTLVNSKADVDMMDKKGCSLLHKAIYRDDKFAANFLIKNGALVNAATVGEQQTPLHLVAS 332

HSP 3 Score: 82.0333 bits (201), Expect = 1.098e-11
Identity = 128/536 (23.88%), Postives = 209/536 (38.99%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIF--------HDEGRNKVNWLMNDYAGES------PFT-LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSN--IISQEG--------FIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA---ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            TP H AV  +N  + N  +          D   +   WL   Y   S      PF  + + NG     +    RLIK    T   D +  +   LL  A   GN  A  FL   G  +N ++    TPL  A      ++   L   GA+PNI +   I S  G           L  PL +A+     D+  +++E  A+          +     KD+ EQT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+NV+   G T+L LA+K +   V+  +       ++S+ D QG+ P   A+E   +  A +++++   A           +  LH A+     +   F+I+   ++N   K               TPLHLA   G  E++++ L+  GAN+  +  E +  +H+A+ ++   II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  369 TPLHAAVLARNDYVFNQLLLCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFDDIPVVNGTSFDENSFAARLIKRGSNTDAPDTVTAN--CLLQRAAAAGNEAASLFLATHGAKVNHKNKWGETPLHTACRHGLSNLTAELLQQGANPNIQTEEPIASTRGSPANSPAESTYLQTPLHMAIAYNHPDVVSVILEQKANALHETNNLQIIPDFSLKDSSEQTVLGLALWTGMHTIAAQLLGSGASINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINVRTRDGETALQLAIKNQLPLVVDAICT--RGADMSVTDEQGNPPLWLALENEQEDIASTLVRHGCDATFWGPGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNSTRKPGPNGEGEEEARDGQTPLHLAASWGL-EEVVQCLLEFGANVNAQDAEGRTPIHVAISNQHRVIIQLLISHPDIRLNVRDRQGMTPFRCAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 880

HSP 4 Score: 64.6994 bits (156), Expect = 2.071e-6
Identity = 119/476 (25.00%), Postives = 190/476 (39.92%), Query Frame = 2

Query: 2600 NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQYHPQAADEIDNLGRN-FLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISG-----------------APEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKM-------------ETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            N + Q G + L+    +AL+     IA  LV + ADVDM      D    +LLH+ I    + AANFLI  G   +  +  E + P + +++  +    +E                         G TPLH A     + V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I        D  D +  N  L  A    N  A  FL    A +N   K+ +  TPLH A   G                   E+ I S   + AN   E+   Q  LH+A+ +    ++S +LE  A+  H+ N +             +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  V  +D  G TAL L A+K+   L V A+  +GA +   + +G
Sbjct:  250 NELDQNGDLSLD----LALSRRLESIATTLVNSKADVDMM-----DKKGCSLLHKAIYRDDKFAANFLIKNGALVNAATVGEQQTPLHLVASCTTKGRSLEVMSDIAQIAETLLKAGANPNMQDSKGRTPLHAAVLARNDYVFNQLLLCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFDDIPVVNGTSFD-ENSFAARLI--KRGSNTDAPDTVTANCLLQRAAAAGNEAASLFLATHGAKVN--HKNKWGETPLHTACRHGLSNLTAELLQQGANPNIQTEEPIASTRGSPANSPAESTYLQTPLHMAIAYNHPDVVSVILEQKANALHETNNLQIIPDFSLKDSSEQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINVRTRD--GETALQL-AIKNQLPLVVDAICTRGADMSVTDEQG 687

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. TrEMBL
Match: A0A1S3HUN5 (rabankyrin-5 OS=Lingula unguis OX=7574 GN=LOC106158344 PE=4 SV=2)

HSP 1 Score: 465.307 bits (1196), Expect = 1.176e-138
Identity = 261/648 (40.28%), Postives = 376/648 (58.02%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKV--------NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVY-IISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            TP HLA+  K++ ++ + + H E   +         N+ + D  G +   L LWNG     + I  +L+      +E D+   +  +LLH A+   ++ +  FL++   DI+ R+ +  +PL LA ++    +V  LC  G D     N++  EG    NCPLW AL   + D+A ILV  G D +MW     D  EQTLLHR I E  E  A FLI   CD  S      P     N E      +G TPLH+A   G E VV+ L+  N + +N Q+A G + +H+A+  +H  +++ +L+    LNL+ RD QG TPF  AM   N KAA++IL   P+AA+++DN GRNFLHVA+Q  + E+V FLI V+A++N RV+D+ ++TPL LA+++ + E ++R+LILAGAN+   T  KQ  LHLA  +++   I S LLENG      D  M   LH+AV+ GN+++ + LL  S    ++ N+KG+  +H+L    REN   IF   L+  PE+P+D+ DA GNT L L  L  N  L  A++  GA +G  N +G ++FN+   ++Q + KLLD L+ EP W DGE C  C  KF IK RKHHCRHCGRL+C KCS  ++PIIK+N  KPVRVC++CF+ L  G
Sbjct:  527 TPLHLAILNKHVNVVRVLLEHKEKATRSTDNTTIIPNFNIKDSRGHTALGLSLWNGF----NDIAVQLLNGGANINEKDE---ENMTLLHQAIMNQDVPSCLFLLENKADISARTADNESPLQLAIKRHLPVVVDALCSRGVD----MNVMDAEG----NCPLWQALETGQEDVASILVRHGCDTNMWGPG-PDGCEQTLLHRAIDENNEAVACFLIRSMCDVNS------PRRPGPNGEGGEEARDGQTPLHLAATWGQEMVVQCLIEHNAV-INAQDAEGKSPIHVAINNQHTVIISLMLS-HPGLNLAARDRQGQTPFAAAMTTKNNKAAQAILDREPRAAEQLDNRGRNFLHVAIQKSDIESVLFLISVHADVNSRVQDSHKFTPLQLAVMASS-EIIVRNLILAGANVNELTPSKQTALHLAAENDQTSSICSVLLENGVDCDALDAGMNNALHVAVQHGNLNVCRVLLTESRINAEAINMKGQTPMHVLGQYGRENAAAIFEFFLECMPEYPIDKPDAEGNTVLLLAYLNGNGHLCRAIVRAGAMMGNVNRQGMSIFNAPVATKQLLFKLLDMLAKEPPWTDGENCEECATKFGIKTRKHHCRHCGRLLCNKCSDKDIPIIKYNQPKPVRVCQICFDVLTLG 1149

HSP 2 Score: 207.608 bits (527), Expect = 1.845e-50
Identity = 115/327 (35.17%), Postives = 176/327 (53.82%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIP 1048
            L  H  LL++EY K+ +KY  L+ KY   +  SG  S   +F   L   +  L+  + +SD++I L    +  HR +  A    W   DL    E++L      +   +VKW Y  +++   +   L +L+K A    L  LKNRCE   +S VS  NCI +Y+ A E   E L+  CS LI  +WN++   DF  + A +   + + ++ YPLH A++  R+DVVFLY+ E  S L   +N +    +L LDLAL +K+  + +TL+    ++N  DN G  LLHKAI+R DEFS  FLI+NG ++N  S    +T + ++A+  P
Sbjct:    9 LQSHLRLLREEYVKLQSKYAELEKKYQVAVAASGQTSGS-SFISRLLTTIADLFDKELYSDLTIHLDGQQLHAHRFVLAARSDHWGVPDLGAVTELDLTGINHEVSFALVKWAYTDQIDIKSDDTFLLELLKAASNFKLDTLKNRCEQALMSSVSVKNCIRYYQTAEEIGAELLKKHCSELISNHWNDFTSEDFACMPAPLLYSMFKTKTQYPLHTAIRTQREDVVFLYLIEFDSLLPGKLNELDNRGDLPLDLALQAKQESIAQTLVGHKVDVNKTDNSGRCLLHKAIRRGDEFSASFLIKNGANVNAASHIEKETALHMVASFNP 334

HSP 3 Score: 82.8037 bits (203), Expect = 5.929e-12
Identity = 132/526 (25.10%), Postives = 226/526 (42.97%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLI-----SVCDKIFE-RLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPN--ITSNI---ISQEGF------IELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLI--SRGCDTISTMENKNPSNSIS----NYESN-NHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHP----QAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNI------------RVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI 3634
            TP H AV +K+  + +  +     +N +   + +  G++     LW GL+     S+ D  F  RLIK       ++    D   LLHL  + G   A  FL+  G  +N+ +     PL  A +K   ++  +L   GA+PN   T+N+   ++  GF      +    PL +A+ N   ++  +L+E           +K+   ++  + TI+       NF I  SRG  T   +   N  N I+    N  +N N   E N  L     M  +      L  NK D++ + A   + L LA+K RH  V+   L  +  +++++ D +G+ P   A+E + Q+   SIL  H           D   +  LH A+   N     FLI+   ++N               +D    TPLHLA   G  E +++ LI   A I  +  E ++ +H+A+ ++   IIS +L + G + + +D + +TP   A+   N    + +L       +  + +G N LH+
Sbjct:  368 TPLHRAVSSKHEAVFSTLL----SQNNLKLELQNADGQT----VLWLGLLDSAGQSIDDNSFAARLIKAGSSPDAVNSETGD--CLLHLTSRAGMEAAALFLVSHGAKLNLINAKGEAPLHTAAQKGLAELAAMLLAKGANPNSQTTANLDTTMATLGFEEESPPVSKQTPLHLAILNKHVNVVRVLLE-----------HKEKATRSTDNTTII------PNFNIKDSRG-HTALGLSLWNGFNDIAVQLLNGGANINEKDEENMTLLHQAIMNQDVPSCLFLLENKADISARTADNESPLQLAIK-RHLPVVVDALCSR-GVDMNVMDAEGNCPLWQALE-TGQEDVASILVRHGCDTNMWGPGPDGCEQTLLHRAIDENNEAVACFLIRSMCDVNSPRRPGPNGEGGEEARDG--QTPLHLAATWGQ-EMVVQCLIEHNAVINAQDAEGKSPIHVAINNQHTVIISLMLSHPGLNLAARDRQGQTPFAAAMTTKNNKAAQAILDREPRAAEQLDNRGRNFLHV 859

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. TrEMBL
Match: A0A1L8HGA0 (Uncharacterized protein OS=Xenopus laevis OX=8355 GN=ankfy1 PE=1 SV=1)

HSP 1 Score: 464.151 bits (1193), Expect = 3.647e-138
Identity = 265/664 (39.91%), Postives = 386/664 (58.13%), Query Frame = 2

Query: 2132 KGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLN-PKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +G   NS    T  L TP H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+++ + ++  FL++   DIN+R+ +  T L LA +     +V  +C  GAD ++T     ++G    N PLW+AL N + DIA  LV  G D   W        +QTLLHR I E KEQ A F+I  GCD  ST   + P     N E      +G TPLH+A   GLE VV+ LL     +VN Q+A G TS+H+A+  +H  ++  L++ P  +LN  +RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   S  D      LHLAV  G ++ I+ LL   +   ++ NL+G++ +HIL    +EN   IF L L+  PE+P+D+ DA GNT L L  +K N+ L  A++  GA LG  N++G  +FN +  ++Q + +LLD LS EP W DG  C+ C+ KF +  RKHHCRHCGRL+C KCS  E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  529 QGSPANSPADSTY-LQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLG-------SGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINIRTRDGETALQLAIKNQLPLVVDAICTRGADMSVTD----EQG----NPPLWLALENGQEDIASTLVRHGCDATFWGPG-PSGCQQTLLHRAIDENKEQIACFIIRSGCDVNST---RKPG---PNGEGEEEARDGQTPLHLAASWGLEEVVQCLLEFGA-NVNTQDAEGRTSIHVAISNQHRVIIQLLISHPDIRLN--VRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPVICSVLLENGVDFSAADENGNNALHLAVMHGRLNNIRCLLTECNVDAEALNLRGQSPMHILGQYGKENAAAIFELFLECMPEYPLDKPDAEGNTVLLLAYIKGNANLCRAIVKAGARLGVNNSQGINIFNYQVATKQLLFRLLDMLSQEPPWCDGSNCYECVAKFGVTTRKHHCRHCGRLLCSKCSTKEIPIIKFDLNKPVRVCDICFDVLTLG 1165

HSP 2 Score: 213.772 bits (543), Expect = 2.119e-52
Identity = 168/586 (28.67%), Postives = 288/586 (49.15%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFN----DKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITA 1792
            L KH  LL+QEY K+  K    + K   L   +   ++ D+F   L  IV  L++ +++SD++IK+    I  H+ +  A    W+ +++++ +E++L +    +   ++ WIY  EL+  ++   L +LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E +   L ++C+ +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  SQL   +N + ++ +L LDLALS +   +  TL+ S A+++ +D  G SLLHKAI R D+F+  FLI+NG  +N  +    QTP+ L+A+        E ++ I  I   L++ GA+                 NM  +   RT L  A+L+ NE V   +L    C  ++        + K    S               LWLA+      +++ +  D +    D V +    +F        LI+  ++     D+ T N ++    + G E A++F L  +  K                   VN  N + E+  H A  + L NL   LLQ GA+PNI  +  I +
Sbjct:    9 LQKHLALLRQEYVKLQQKLAETEKKCTLLAAQTNKEASSDSFISRLLFIVAQLFQQEQYSDLTIKIGDKHINAHKFVLAARSEVWSPANMASTKELDLSDSNPEVTMAMLCWIYTDELDLREDDIFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTQFPLHKAIKLEREDVVFLYLIEMDSQLPGKLNELDQNGDLSLDLALSRRLESIAITLVNSKADVDMMDKKGCSLLHKAIYRDDKFAATFLIKNGALVNAATLGEQQTPLHLVASCTTKDRSLEVMSDIAQIAETLLKAGANP----------------NMQ-DSKGRTPLHTAVLARNEYVFNQLL---LCKQLD-------LELKDHEGST-------------ALWLAV------QYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKRGSNTDA-PDTATANCLLQRASAAGNEAASLF-LATHGAK-------------------VNHKNKWGETPLHTACRHGLSNLTAELLQQGANPNIQTQEAIVS 527

HSP 3 Score: 90.5077 bits (223), Expect = 2.523e-14
Identity = 127/536 (23.69%), Postives = 210/536 (39.18%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIF--------HDEGRNKVNWLMNDYAGES------PFT-LCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSN--IISQEG--------FIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA---ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLEN-GASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            TP H AV  +N  + N  +          D   +   WL   Y   S      PF  + + NG     +    RLIK    T   D    +   LL  A   GN  A  FL   G  +N ++    TPL  A      ++   L   GA+PNI +   I+S +G           L  PL +A+     D+  +++E  A+          +     KD+ EQT+L   +       A  L+  G     TM                   +G T LHMA Q   +S     L  ++ D+N++   G T+L LA+K +   V+  +       ++S+ D QG+ P   A+E   +  A +++++   A           +  LH A+     +   F+I+   ++N   K               TPLHLA   G  E++++ L+  GAN+  +  E +  +H+A+ ++   II  L+ +     + +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  369 TPLHTAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFDDVPVVNGTSFDENSFAARLIKRGSNTDAPDTATAN--CLLQRASAAGNEAASLFLATHGAKVNHKNKWGETPLHTACRHGLSNLTAELLQQGANPNIQTQEAIVSPQGSPANSPADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTGMHTIAAQLLGSGASINDTMS------------------DGQTLLHMAIQRQ-DSKSALFLLEHQADINIRTRDGETALQLAIKNQLPLVVDAICT--RGADMSVTDEQGNPPLWLALENGQEDIASTLVRHGCDATFWGPGPSGCQQTLLHRAIDENKEQIACFIIRSGCDVNSTRKPGPNGEGEEEARDGQTPLHLAASWGL-EEVVQCLLEFGANVNTQDAEGRTSIHVAISNQHRVIIQLLISHPDIRLNVRDRQGMTPFACAMTFKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 880

HSP 4 Score: 67.781 bits (164), Expect = 2.455e-7
Identity = 119/477 (24.95%), Postives = 191/477 (40.04%), Query Frame = 2

Query: 2600 NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC--DTISTMENKNPSNSISNYESNNHYIE-------------------------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-------TAMELSNQKAARSILQYHPQAADEIDNLGRN-FLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEK------------------QNLLHLAVIHERVYIISFLLENGASTSH-------------QDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGV-ALLLKGASLGCFNNEG 3829
            N + Q G + L+    +AL+     IA  LV + ADVDM      D    +LLH+ I    + AA FLI  G   +  +  E + P + +++  + +  +E                         G TPLH A     E V   LL   ++D+ +++  G T+L LAV++                 +++   Q   PF        T+ +  N  AAR I        D  D    N  L  A    N  A  FL    A +N   K+ +  TPLH A   G   +L   L+  GAN   +T E                   Q  LH+A+ +    ++S +LE  A+  H             +D++ +T L LA+  G +  I   L  S  +I      G+ +LH+     +++   +F  +L+H  +  +  +D  G TAL L A+K+   L V A+  +GA +   + +G
Sbjct:  250 NELDQNGDLSLD----LALSRRLESIAITLVNSKADVDMM-----DKKGCSLLHKAIYRDDKFAATFLIKNGALVNAATLGEQQTPLHLVASCTTKDRSLEVMSDIAQIAETLLKAGANPNMQDSKGRTPLHTAVLARNEYVFNQLLLCKQLDLELKDHEGSTALWLAVQY-----------------ITVSSDQSVNPFDDVPVVNGTSFD-ENSFAARLI--KRGSNTDAPDTATANCLLQRASAAGNEAASLFLATHGAKVN--HKNKWGETPLHTACRHGL-SNLTAELLQQGANPNIQTQEAIVSPQGSPANSPADSTYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSREQTVLGLALWTG-MHTIAAQLLGSGASINDTMSDGQTLLHMAIQR-QDSKSALF--LLEHQADINIRTRD--GETALQL-AIKNQLPLVVDAICTRGADMSVTDEQG 687

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Cavefish
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 453.751 bits (1166), Expect = 6.721e-138
Identity = 257/658 (39.06%), Postives = 380/658 (57.75%), Query Frame = 2

Query: 2147 NSDKQLTIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            +SD+   + L +P H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+K+ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     +++ ++G    + PLW+AL N   DIA  LV  G D   WS       +QTLLHR I E  E  A FLI  GCD  S      P     N E +    +G +PLH+A   GLE VV+ LL     +VN Q++ G   +HLA+  +H +V+  LL    ++ LS+RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ ++ LL  S+   ++ NL+G++ +H+L +  +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS+ E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  509 DSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGAD----MSVVDEKG----DPPLWLALENGLEDIASTLVRHGCDATCWSTG-PGGCQQTLLHRAIDENNEVTACFLIRSGCDVNS------PRKPGPNGEGDEEARDGQSPLHLASCWGLEEVVQCLLEFGA-NVNAQDSEGRAPIHLAISNQH-SVIIQLLISHPEIRLSLRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDAAKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLATICSVLLENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNIDAEAYNLRGQSPMHVLGHYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVNNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSIKEIPIIKFDLNKPVRVCDICFDVLTLG 1141

HSP 2 Score: 211.075 bits (536), Expect = 5.907e-55
Identity = 157/533 (29.46%), Postives = 260/533 (48.78%), Query Frame = 2

Query:  191 FWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNI 1768
            F   L  IV  LY+  ++SD+ +K+ +  +  H+ +  A    W+ ++L++  E++L   +  +   +++W Y  EL  N++   L  LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  +QL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P     E ++ +  I   L++ GA+                 NM  N   RT L  A+LSGNE V   +L   +C  ++            + ++A+  A  +I+V   P          P        F D V +    +F        LI+  ++P       +GN ++      G E AAIF            L   G        ++VN TN + E+  H A    L  L   LLQ GA+PN+
Sbjct:   32 FISRLLAIVSDLYQQDQYSDLKVKIGQQKLSAHKFVLAARSDIWSLANLASISELDLSEAKPEVAMAMLRWAYTDELEMNEDDTFLIDLMKLANRFQLQLLRERCEKGVMSSVNVRNCIRFYQTAEELDATTLMNYCGEIIASHWDDLRKEDFSTMSAQLLYKMIKSKTEFPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSRKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSTEVMSGMAHIAEALLKTGANP----------------NMQ-NSRGRTPLHEAVLSGNEPVFNQLL---QCKQLD------LELKDHEGSTALWLALQYITVASDP-------SVNP--------FEDDVPVVNGTSFDENSFAARLIQRGSNPDA--PDASGNCLMQRAALAGSEAAAIF------------LATHG--------AVVNHTNKWGETPLHTACRCGLAGLTAELLQQGANPNL 501

HSP 3 Score: 68.9366 bits (167), Expect = 4.205e-11
Identity = 96/421 (22.80%), Postives = 169/421 (40.14%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNII----SQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N  +    TPL  A       +   L   GA+PN+ +        +   + L  PL +A+ +   D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA +   +S     L  ++ D+NV+   G T+L LA+  +   V+  +       ++S+ D +G  P   A+E   +  A +++++   A       G   +  LH A+   N     FLI+   ++N   K               +PLHLA   G  E++++ L+  GAN+  +  E +  +HLA+ ++   II  L+ +     S +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  458 FLATHGAVVNHTNKWGETPLHTACRCGLAGLTAELLQQGANPNLQTQSALPDSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIKRQ-DSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICT--RGADMSVVDEKGDPPLWLALENGLEDIASTLVRHGCDATCWSTGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSPRKPGPNGEGDEEARDGQSPLHLASCWGL-EEVVQCLLEFGANVNAQDSEGRAPIHLAISNQHSVIIQLLISHPEIRLSLRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 856

HSP 4 Score: 67.0106 bits (162), Expect = 1.329e-10
Identity = 131/652 (20.09%), Postives = 249/652 (38.19%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGR--NKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKM-TPLLL---------ATE--KSNIDIVRILCLSGADPNITSN---IISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHY-------------------------KDNYEQTLLHR-TILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGC------------TSLHLAVKFRHEAVLTHLLNPKYKL-----------NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAP--------------------------------EDLIRSLILAGANIANETIE----KQNLLHLAVIHERVYIISFLLENG------------ASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLK 3796
            P H A+K +   ++ L++   + +   K+N L N+  G+    L L   L S+   +           +++D +     SLLH A+++G+  A  FLI+    +N  ++  + TPL L         +TE       I   L  +GA+PN+ ++       E  +  N P++  L  C+    ++    G+     ++ Y                         ++++   L+ R +  +  + + N L+ R     S       +   +     N +  G TPLH AC+ GL  +   LL     + N+Q  +              + LH+A+   H  V++ +L  K              + S++D    T    A+       A  +L       D + + G+  LH+A++  + ++  FL++  A++N+R ++    T L LAI +  P                                ED+  +L+  G +    +      +Q LLH A+         FL+ +G                 +    ++PLHLA   G  ++++ LL      + +++ +G   +H+  +N      VI  L++ H PE  +  +D  G T  F CA+   +      +LK
Sbjct:  203 PLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNN--GDLALDLALSRKLESIATTLVN-------NKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSTEVMSGMAHIAEALLKTGANPNMQNSRGRTPLHEAVLSGNEPVFNQLLQCKQLDLELKDHEGSTALWLALQYITVASDPSVNPFEDDVPVVNGTSFDENSFAARLIQRGSNPDAPDASGNCLMQRAALAGSEAAAIFLATHGAVVNHTNKW--GETPLHTACRCGLAGLTAELLQQGA-NPNLQTQSALPDSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSD-GQTLLHMAIKRQDSKSALFLLEHQADINVRTQEG--QTALQLAISNQLPLVVDAICTRGADMSVVDEKGDPPLWLALENGLEDIASTLVRHGCDATCWSTGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSPRKPGPNGEGDEEARDGQSPLHLASCWGLEEVVQCLL-EFGANVNAQDSEGRAPIHLAISNQHS---VIIQLLISH-PEIRLSLRDRQGMTP-FACAMTHKNNKAAEAILK 833

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Cavefish
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 388.652 bits (997), Expect = 3.393e-114
Identity = 234/630 (37.14%), Postives = 350/630 (55.56%), Query Frame = 2

Query: 2147 NSDKQLTIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHH-----CRHCGRLV 3997
            +SD+   + L +P H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+K+ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     +++ ++G    + PLW+AL N   DIA  LV  G D   WS       +QTLLHR I E  E  A FLI  GCD  S      P     N E +    +G +PLH+A   GLE VV+ LL     +VN Q++ G   +HLA+  +H +V+  LL    ++ LS+RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ ++ LL  S+   ++ NL+G++ +H+L +  +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHH     C HC + V
Sbjct:  509 DSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGAD----MSVVDEKG----DPPLWLALENGLEDIASTLVRHGCDATCWSTG-PGGCQQTLLHRAIDENNEVTACFLIRSGCDVNS------PRKPGPNGEGDEEARDGQSPLHLASCWGLEEVVQCLLEFGA-NVNAQDSEGRAPIHLAISNQH-SVIIQLLISHPEIRLSLRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDAAKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLATICSVLLENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNIDAEAYNLRGQSPMHVLGHYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVNNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHWYVTACCHCFKTV 1113

HSP 2 Score: 210.69 bits (535), Expect = 8.025e-55
Identity = 157/533 (29.46%), Postives = 260/533 (48.78%), Query Frame = 2

Query:  191 FWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNI 1768
            F   L  IV  LY+  ++SD+ +K+ +  +  H+ +  A    W+ ++L++  E++L   +  +   +++W Y  EL  N++   L  LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  +QL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P     E ++ +  I   L++ GA+                 NM  N   RT L  A+LSGNE V   +L   +C  ++            + ++A+  A  +I+V   P          P        F D V +    +F        LI+  ++P       +GN ++      G E AAIF            L   G        ++VN TN + E+  H A    L  L   LLQ GA+PN+
Sbjct:   32 FISRLLAIVSDLYQQDQYSDLKVKIGQQKLSAHKFVLAARSDIWSLANLASISELDLSEAKPEVAMAMLRWAYTDELEMNEDDTFLIDLMKLANRFQLQLLRERCEKGVMSSVNVRNCIRFYQTAEELDATTLMNYCGEIIASHWDDLRKEDFSTMSAQLLYKMIKSKTEFPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSRKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSTEVMSGMAHIAEALLKTGANP----------------NMQ-NSRGRTPLHEAVLSGNEPVFNQLL---QCKQLD------LELKDHEGSTALWLALQYITVASDP-------SVNP--------FEDDVPVVNGTSFDENSFAARLIQRGSNPDA--PDASGNCLMQRAALAGSEAAAIF------------LATHG--------AVVNHTNKWGETPLHTACRCGLAGLTAELLQQGANPNL 501

HSP 3 Score: 68.5514 bits (166), Expect = 4.526e-11
Identity = 96/421 (22.80%), Postives = 169/421 (40.14%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNII----SQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N  +    TPL  A       +   L   GA+PN+ +        +   + L  PL +A+ +   D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA +   +S     L  ++ D+NV+   G T+L LA+  +   V+  +       ++S+ D +G  P   A+E   +  A +++++   A       G   +  LH A+   N     FLI+   ++N   K               +PLHLA   G  E++++ L+  GAN+  +  E +  +HLA+ ++   II  L+ +     S +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  458 FLATHGAVVNHTNKWGETPLHTACRCGLAGLTAELLQQGANPNLQTQSALPDSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIKRQ-DSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICT--RGADMSVVDEKGDPPLWLALENGLEDIASTLVRHGCDATCWSTGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSPRKPGPNGEGDEEARDGQSPLHLASCWGL-EEVVQCLLEFGANVNAQDSEGRAPIHLAISNQHSVIIQLLISHPEIRLSLRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 856

HSP 4 Score: 67.0106 bits (162), Expect = 1.326e-10
Identity = 143/673 (21.25%), Postives = 251/673 (37.30%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGR--NKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKM-TPLLL---------ATE--KSNIDIVRILCLSGADPNITSN---IISQEGFIELNCP-----------------------LWVAL---------------------NNCRFD---IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGC------------TSLHLAVKFRHEAVLTHLLNPKYKL-----------NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAP--------------------------------EDLIRSLILAGANIANETIE----KQNLLHLAVIHERVYIISFLLENG------------ASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLK 3796
            P H A+K +   ++ L++   + +   K+N L N+  G+    L L   L S+   +           +++D +     SLLH A+++G+  A  FLI+    +N  ++  + TPL L         +TE       I   L  +GA+PN+ ++       E  +  N P                       LW+AL                     N   FD    A  L++ G++ D       D     L+ R  L   E AA FL + G              ++ N+   N +  G TPLH AC+ GL  +   LL     + N+Q  +              + LH+A+   H  V++ +L  K              + S++D    T    A+       A  +L       D + + G+  LH+A++  + ++  FL++  A++N+R ++    T L LAI +  P                                ED+  +L+  G +    +      +Q LLH A+         FL+ +G                 +    ++PLHLA   G  ++++ LL      + +++ +G   +H+  +N      VI  L++ H PE  +  +D  G T  F CA+   +      +LK
Sbjct:  203 PLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNN--GDLALDLALSRKLESIATTLVN-------NKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSTEVMSGMAHIAEALLKTGANPNMQNSRGRTPLHEAVLSGNEPVFNQLLQCKQLDLELKDHEGSTALWLALQYITVASDPSVNPFEDDVPVVNGTSFDENSFAARLIQRGSNPDA-----PDASGNCLMQRAALAGSEAAAIFLATHG--------------AVVNH--TNKW--GETPLHTACRCGLAGLTAELLQQGA-NPNLQTQSALPDSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSD-GQTLLHMAIKRQDSKSALFLLEHQADINVRTQEG--QTALQLAISNQLPLVVDAICTRGADMSVVDEKGDPPLWLALENGLEDIASTLVRHGCDATCWSTGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSPRKPGPNGEGDEEARDGQSPLHLASCWGLEEVVQCLL-EFGANVNAQDSEGRAPIHLAISNQHS---VIIQLLISH-PEIRLSLRDRQGMTP-FACAMTHKNNKAAEAILK 833

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Cavefish
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 388.652 bits (997), Expect = 4.566e-114
Identity = 234/630 (37.14%), Postives = 350/630 (55.56%), Query Frame = 2

Query: 2147 NSDKQLTIDLCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHH-----CRHCGRLV 3997
            +SD+   + L +P H+A+   +  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + D Q+LLH+A+K+ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     +++ ++G    + PLW+AL N   DIA  LV  G D   WS       +QTLLHR I E  E  A FLI  GCD  S      P     N E +    +G +PLH+A   GLE VV+ LL     +VN Q++ G   +HLA+  +H +V+  LL    ++ LS+RD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLENG   +  D      LHLAV  G ++ ++ LL  S+   ++ NL+G++ +H+L +  +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHH     C HC + V
Sbjct:  535 DSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLG-------SGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGAD----MSVVDEKG----DPPLWLALENGLEDIASTLVRHGCDATCWSTG-PGGCQQTLLHRAIDENNEVTACFLIRSGCDVNS------PRKPGPNGEGDEEARDGQSPLHLASCWGLEEVVQCLLEFGA-NVNAQDSEGRAPIHLAISNQH-SVIIQLLISHPEIRLSLRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDAAKLTPLHLAVQAGS-EIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLATICSVLLENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNIDAEAYNLRGQSPMHVLGHYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVNNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHWYVTACCHCFKTV 1139

HSP 2 Score: 218.009 bits (554), Expect = 4.430e-57
Identity = 169/580 (29.14%), Postives = 279/580 (48.10%), Query Frame = 2

Query:   62 ETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDN----FWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNI 1768
            + L KH  LL+QEY K+  K    + +   L   +   S+       F   L  IV  LY+  ++SD+ +K+ +  +  H+ +  A    W+ ++L++  E++L   +  +   +++W Y  EL  N++   L  LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  + A +   ++++++ +PLH+A+K  R+DVVFLY+ E  +QL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P     E ++ +  I   L++ GA+                 NM  N   RT L  A+LSGNE V   +L   +C  ++            + ++A+  A  +I+V   P          P        F D V +    +F        LI+  ++P       +GN ++      G E AAIF            L   G        ++VN TN + E+  H A    L  L   LLQ GA+PN+
Sbjct:   11 QKLQKHLALLRQEYVKMQQKLVETERRCSMLAAQASGHSSSSQPSDSFISRLLAIVSDLYQQDQYSDLKVKIGQQKLSAHKFVLAARSDIWSLANLASISELDLSEAKPEVAMAMLRWAYTDELEMNEDDTFLIDLMKLANRFQLQLLRERCEKGVMSSVNVRNCIRFYQTAEELDATTLMNYCGEIIASHWDDLRKEDFSTMSAQLLYKMIKSKTEFPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSRKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSTEVMSGMAHIAEALLKTGANP----------------NMQ-NSRGRTPLHEAVLSGNEPVFNQLL---QCKQLD------LELKDHEGSTALWLALQYITVASDP-------SVNP--------FEDDVPVVNGTSFDENSFAARLIQRGSNPDA--PDASGNCLMQRAALAGSEAAAIF------------LATHG--------AVVNHTNKWGETPLHTACRCGLAGLTAELLQQGANPNL 527

HSP 3 Score: 68.5514 bits (166), Expect = 5.491e-11
Identity = 96/421 (22.80%), Postives = 169/421 (40.14%), Query Frame = 2

Query: 2462 FLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNII----SQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            FL   G  +N  +    TPL  A       +   L   GA+PN+ +        +   + L  PL +A+ +   D+  +++E  A+          +     KD+ +QT+L   +       A  L+  G     TM                   +G T LHMA +   +S     L  ++ D+NV+   G T+L LA+  +   V+  +       ++S+ D +G  P   A+E   +  A +++++   A       G   +  LH A+   N     FLI+   ++N   K               +PLHLA   G  E++++ L+  GAN+  +  E +  +HLA+ ++   II  L+ +     S +D +  TP   A+   N    + +L       +  + KG N LH+   N
Sbjct:  484 FLATHGAVVNHTNKWGETPLHTACRCGLAGLTAELLQQGANPNLQTQSALPDSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLGSGAAINDTMS------------------DGQTLLHMAIKRQ-DSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICT--RGADMSVVDEKGDPPLWLALENGLEDIASTLVRHGCDATCWSTGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSPRKPGPNGEGDEEARDGQSPLHLASCWGL-EEVVQCLLEFGANVNAQDSEGRAPIHLAISNQHSVIIQLLISHPEIRLSLRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQN 882

HSP 4 Score: 67.0106 bits (162), Expect = 1.404e-10
Identity = 143/673 (21.25%), Postives = 251/673 (37.30%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGR--NKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKM-TPLLL---------ATE--KSNIDIVRILCLSGADPNITSN---IISQEGFIELNCP-----------------------LWVAL---------------------NNCRFD---IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGC------------TSLHLAVKFRHEAVLTHLLNPKYKL-----------NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAP--------------------------------EDLIRSLILAGANIANETIE----KQNLLHLAVIHERVYIISFLLENG------------ASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLK 3796
            P H A+K +   ++ L++   + +   K+N L N+  G+    L L   L S+   +           +++D +     SLLH A+++G+  A  FLI+    +N  ++  + TPL L         +TE       I   L  +GA+PN+ ++       E  +  N P                       LW+AL                     N   FD    A  L++ G++ D       D     L+ R  L   E AA FL + G              ++ N+   N +  G TPLH AC+ GL  +   LL     + N+Q  +              + LH+A+   H  V++ +L  K              + S++D    T    A+       A  +L       D + + G+  LH+A++  + ++  FL++  A++N+R ++    T L LAI +  P                                ED+  +L+  G +    +      +Q LLH A+         FL+ +G                 +    ++PLHLA   G  ++++ LL      + +++ +G   +H+  +N      VI  L++ H PE  +  +D  G T  F CA+   +      +LK
Sbjct:  229 PLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNN--GDLALDLALSRKLESIATTLVN-------NKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSTEVMSGMAHIAEALLKTGANPNMQNSRGRTPLHEAVLSGNEPVFNQLLQCKQLDLELKDHEGSTALWLALQYITVASDPSVNPFEDDVPVVNGTSFDENSFAARLIQRGSNPDA-----PDASGNCLMQRAALAGSEAAAIFLATHG--------------AVVNH--TNKW--GETPLHTACRCGLAGLTAELLQQGA-NPNLQTQSALPDSDRSHGVSLQSPLHMAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSLDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSD-GQTLLHMAIKRQDSKSALFLLEHQADINVRTQEG--QTALQLAISNQLPLVVDAICTRGADMSVVDEKGDPPLWLALENGLEDIASTLVRHGCDATCWSTGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSPRKPGPNGEGDEEARDGQSPLHLASCWGLEEVVQCLL-EFGANVNAQDSEGRAPIHLAISNQHS---VIIQLLISH-PEIRLSLRDRQGMTP-FACAMTHKNNKAAEAILK 859

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Cavefish
Match: ENSAMXT00000017800.2 (pep primary_assembly:Astyanax_mexicanus-2.0:16:21012912:21225385:-1 gene:ENSAMXG00000017269.2 transcript:ENSAMXT00000017800.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 137.502 bits (345), Expect = 7.307e-32
Identity = 138/524 (26.34%), Postives = 236/524 (45.04%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTME---NKNPSNSISNYESNNHYI---EGNTPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLLDSLSSEPN 3907
            + S +D       + LH+A   G  E V+ L+K G DIN +S N  TPL +A++++++D+VR L  +G + +  +    ++GF     PL +AL      +  IL+E      V + ++H     + T     +L+  +  A+     G   +       N N +  + N  +   +     G TPLH+A + G  ++V+ LL   ++ID   ++  G T LH A +  H+  +  LL  +    +  R   G +P H A +  + +  + +LQ H    D++       LHVA    +      L+   AN N R      +TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G V++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +    +   LL  GAS      +GFT     H++ ++    + KLL    + P+
Sbjct:   87 RGSSVDSATKKGNTALHIASLAGQAEVVKILVKQGADINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSTAT----EDGFT----PLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQ-NDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARQNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRD--GLTPLHCAARSGHDTAVELLL--ERGAPILARTKNGLSPLHMAAQGDHVECVKHLLQ-HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALLQNGFTPLHIACKKNRVK-VMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQVEVVRCLLRNGA-MVDARAREDQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQLDVASVLLEAGASHSLATKKGFTPL---HVASKYGSLDVAKLLLQRRAPPD 586

HSP 2 Score: 115.546 bits (288), Expect = 3.599e-25
Identity = 116/405 (28.64%), Postives = 177/405 (43.70%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLL-ANSSTTIKSKNLKGENILH 3631
            LH+A KK  ++ ++ L+K G  I   + + +TP+ +A    +++IV +L  +GA P++ SNI  +         L +A    + ++   L+  GA VD      +   +QT LH      K +    L+             +P  + +N         G TPLH++ + G   V   LL +     ++    G T LH+A K+    V   LL  +   + + ++  G TP H A    NQK A  +L           N G   LH+A +    E    L+Q  A  NI  K     TPLHLA   G   D+   L+  GA +   T      LHLA   +RV +   L++NGAS   Q     TPL +A   GN  ++  LL +N+S   K+KN  G   LH
Sbjct:  398 LHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDV-SNIRGETA-------LHMAARAGQVEVVRCLLRNGAMVDA-----RAREDQTPLHIASRLGKTEIVQLLLQ---------HMAHPDAATTN---------GYTPLHISAREGQLDVASVLLEAGA-SHSLATKKGFTPLHVASKYGSLDVAKLLLQRRAPPDSAGKN--GLTPLHVAAHYDNQKVALLLLDKGASPHATAKN-GYTPLHIAAKKNQMEIATTLLQYEAETNILTKQGV--TPLHLASQEGH-SDMAALLLQKGAQVNVPTKSGLTALHLAAQEDRVGVAEILVKNGASMDQQTKLGYTPLIVACHYGNAKMVNFLLKSNASVNAKTKN--GYTPLH 762

HSP 3 Score: 102.064 bits (253), Expect = 3.512e-21
Identity = 144/568 (25.35%), Postives = 245/568 (43.13%), Query Frame = 2

Query: 2189 HLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNI--TSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVD------MWSIHYKDNYEQTLLHRTILEMKEQA-ANFLISRGCDTISTMENKNPSNSIS---NYESNNHYI--EGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQY--HPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLA-NSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLL--KGASLGCFNNEGFT 3835
            H+A +  + K   L + +D      N  +   +G +P  +    G ++V   +  R    DF   +      +  + LH+A K+GN   V+ L+  G  I+ ++ + +TPL  A    +   V +L   GA P +  T N +S         PL +A      +    L++  A VD      + ++H   +     + + +L+ +    A  L+  G   +     KN    +     Y ++   I   G TP+H+A  MG  ++V  LL  N    +V N  G T+LH+A +     V+  LL     ++   R+ Q  TP H A  L   +  + +LQ+  HP AA      G   LH++ +    +    L++  A+ ++  K  F  TPLH+A   G+  D+ + L+   A   +        LH+A  ++   +   LL+ GAS         TPLH+A +   +++   LL   + T I +K  +G   LH+ S     +   + +L+L    +  V  K   G TAL L A +D  R+GVA +L   GAS+      G+T
Sbjct:  198 HIAARKDDTKSAALLLQNDH-----NADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARQ------NGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHDTAVELLLERGA-PILARTKNGLS---------PLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALLQNGFTPLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVL-LLLQNGASPDVSNIRGETALHMAARAGQVEVVRCLLRNGAMVDARAREDQ--TPLHIASRLGKTEIVQLLLQHMAHPDAAT---TNGYTPLHISAREGQLDVASVLLEAGASHSLATKKGF--TPLHVASKYGSL-DVAKLLLQRRAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYEAETNILTK--QGVTPLHLASQEGHSD---MAALLLQKGAQVNVPTKS--GLTALHLAAQED--RVGVAEILVKNGASMDQQTKLGYT 726

HSP 4 Score: 92.4337 bits (228), Expect = 3.423e-18
Identity = 112/447 (25.06%), Postives = 197/447 (44.07%), Query Frame = 2

Query: 2429 AVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYI----EGNT-------PLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLA------------IISGAPEDLIRSLILAGANIA-------------------NETIEKQN---LLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI 3634
            A + GNI+ V   +K G DI   + N +  L LA ++ ++D+V+ L   G+    + +  +++G    N  L +A    + ++  ILV+ GAD++  S   ++ +  T L+    E       +L+  G +  +  E+     +I+  + +N  +    E +T        LH+A +   ++    LL  N  + +VQ+ +G T LH+A  + +  V T LLN    ++ + R   G TP H A +  N    R +L    Q  D     G   LH A ++ +  AV  L++  A +  R K+    +PLH+A            +   AP D +    L   ++A                   N     QN    LH+A    RV ++  L++ GAS         TP+H+A   G+++++  LL N ++   S N++GE  LH+
Sbjct:   39 AARAGNIDKVLEYLKGGVDIGTSNQNGLNALHLAAKEGHMDLVQELLERGS----SVDSATKKG----NTALHIASLAGQAEVVKILVKQGADINAQS---QNGF--TPLYMASQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKD-DTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTAR-QNGITPLHVASKRGNTNMVRLLLDRGSQ-IDAKTRDGLTPLHCAARSGHDTAVELLLERGAPILARTKNGL--SPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALLQNGFTPLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVS-NIRGETALHM 466

HSP 5 Score: 78.1814 bits (191), Expect = 7.949e-14
Identity = 88/405 (21.73%), Postives = 161/405 (39.75%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWS------IHYKDNYEQTLLHRTILEMK----------------------EQAANFLISRGCDTISTMEN----------KNP---SNSISNYESNNHYI--EGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVK------------------------FRHEAVLTHLLNPKY-----KLNLSI--RDHQGHTPFHTAMELSNQKAARSILQY 3172
            TP H+A K   +K++ L + +      +       +G +P  +  + G +++   + +     D          I  ++ LH+A + G +E V+ L++ G  ++ R+    TPL +A+     +IV++L    A P+  +      G+     PL ++    + D+A +L+EAGA   + +      +H    Y    + + +L+ +                      ++ A  L+ +G    +T +N          KN    + ++  YE+  + +  +G TPLH+A Q G  S +  LL      VNV   +G T+LHLA +                        +    V  H  N K      K N S+  +   G+TP H A +  N      +LQY
Sbjct:  396 TPLHIACKKNRVKVMELLVKYGASIQAIT-----ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSN-------IRGETALHMAARAGQVEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATT----NGYT----PLHISAREGQLDVASVLLEAGASHSLATKKGFTPLHVASKYGSLDVAKLLLQRRAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYEAETNILTKQGVTPLHLASQEG-HSDMAALLLQKGAQVNVPTKSGLTALHLAAQEDRVGVAEILVKNGASMDQQTKLGYTPLIVACHYGNAKMVNFLLKSNASVNAKTKNGYTPLHQAAQQGNTHIINVLLQY 779

HSP 6 Score: 58.151 bits (139), Expect = 9.264e-8
Identity = 61/222 (27.48%), Postives = 99/222 (44.59%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEM-----KEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLS----SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHL 3058
            LH+A KK  +E    L++   + N+ +   +TPL LA+++ + D+  +L   GA  N+ +    + G   L+    +A    R  +A+ILV+ GA +D          +QT L  T L +       +  NFL+               SN+  N ++ N Y    TPLH A Q G   ++  LL      N I VN     G T+L +A +  + +V+  L
Sbjct:  629 LHIAAKKNQMEIATTLLQYEAETNILTKQGVTPLHLASQEGHSDMAALLLQKGAQVNVPT----KSGLTALH----LAAQEDRVGVAEILVKNGASMD----------QQTKLGYTPLIVACHYGNAKMVNFLLK--------------SNASVNAKTKNGY----TPLHQAAQQGNTHIINVLLQYGAKPNAITVN-----GNTALAIARRLGYISVVDTL 809

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1])

HSP 1 Score: 127.872 bits (320), Expect = 4.193e-29
Identity = 152/599 (25.38%), Postives = 255/599 (42.57%), Query Frame = 2

Query: 2135 GRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELN--CPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENK-NP-----------------SNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILS--NNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQ 3865
            G  VN+  Q   +  TP ++A +  +++++   + H   ++     +    G +P  + L  G     D++   L++ D K     K+ +     LH+A +K + ++   L++   + +V S +  TPL +A    NI++  +L   GA  +          F+  N   PL VA      ++  +L++ GA +D  +   KD    T LH       EQ    L+ RG   +S  +N  +P                  + +   +  N Y+   T LH+A   G   V K ++   K + N +   G T LH+A K     V+  LL  K+  +L      G TP H A  + ++   +  L +H  + +  +  G   LH+A +    + V +L+Q  A ++I+ KD    T LH+A   G  E +++ L+  GA  +  T      LHLAV        S LLE+GAS S    K  TPLH+A + G ++  K LL        +    G   LH+ +  +N R     +  L+LDH        K+  G T L + A K+   +G  LL  GA       +G +     H++ Q
Sbjct:  132 GANVNAQSQ---NGFTPLYMAAQENHLEVVRFLLEHGASQS-----IATEDGFTPLAVALQQG----HDQVVSLLLENDTK----GKVRL---PALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVD----------FMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKT---KDGL--TPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYL---TALHVAAHCGHYKVAK-VIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLL--KHGASLQAVTESGLTPIHVAAFMGHENIVKQ-LTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKD--DQTALHIASRLGKAE-IVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAK-LLLQKRAAPDTAGKTGLTPLHVAAHYDNQR-----VALLLLDHGASPHAAAKN--GYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPL---HLAAQ 675

HSP 2 Score: 122.094 bits (305), Expect = 2.719e-27
Identity = 136/510 (26.67%), Postives = 229/510 (44.90%), Query Frame = 2

Query: 2381 SEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIH---YKDNYEQTLL-----HRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLSSN-KIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTT-IKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF 3868
            + +D       + LH+A   G  + V+ L+  G ++N +S N  TPL +A +++++++VR L   GA    + +I +++GF     PL VAL      +  +L+E      V + ++H    KD+ +   L     H   +E K       I+      +   N N +  + N  +   ++  N  TPLH+A + G  ++VK LL    KID   ++  G T LH   +  HE V+  LL+    + LS +   G +P H A +  +    + +LQ H    D++ N     LHVA    + +    ++   AN N +  + F  TPLH+A      + ++  L+  GA++   T      +H+A       I+  L  +GAS +  + + ET LH+A R G  D+++ LL N +   IK+K+   +  LHI S   R     I  L+L              G T L L   + +      LL  GASL     +GFT     H++ ++
Sbjct:  100 ASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGA----SQSIATEDGF----TPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIA------AHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKD--GLTPLHCGARSGHEQVVEMLLDRGAPI-LS-KTKNGLSPLHMATQGDHLNCVQLLLQ-HDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGF--TPLHIACKKNRVK-VMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKD--DQTALHIAS---RLGKAEIVQLLLQKGAW--ASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPL---HVAAKY 577

HSP 3 Score: 116.316 bits (290), Expect = 1.474e-25
Identity = 124/488 (25.41%), Postives = 222/488 (45.49%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC-DTISTMENKNP---SNSISNYESNNHYIE-----------GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLI---RSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSST 3589
            +P H+A +  ++  + L + HD     V+ + NDY   +   +    G   V   I ++    + K        ++  + LH+A KK  ++ ++ L+K G  +   + + +TP+ +A    + +IV+ L   GA PN T+        +     L +A    + D+   L++ GA VD   I  KD  +QT LH      K +    L+ +G   + +T     P   +    + E+ +  +E           G TPLH+A + G     K LL   +   +    TG T LH+A  + ++ V   LL+     + + ++  G+TP H A + +  +   ++L++  +  + +   G + LH+A Q  + + V  L+  NAN+N+  K+    TPLHLA    A ED +     L+  GA +   T      LH+A  +  + ++SFLLEN A  + +     TPLH A + G+  +I  LL + ++
Sbjct:  338 SPLHMATQGDHLNCVQLLLQHDV---PVDDVTNDYL--TALHVAAHCGHYKVAKVIVDKKANPNAK-------ALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTN--------VRGETALHMAARAGQADVVRYLLQNGAKVD---IKAKD--DQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAK-LLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKN--GYTPLHIAAKKNQLEIGTTLLEFGAET-NAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGL--TPLHLA----AQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRAS 790

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Sea Lamprey
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 444.891 bits (1143), Expect = 3.282e-135
Identity = 258/647 (39.88%), Postives = 364/647 (56.26%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDE-GRNKVNWL-------MNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            TP HLA+   + +++ +F+       N VN L       + D   ++   L LW G+     KI  +L+ +    + I++   D Q+LLH A+ K N +   FL++   DIN+R+    TPL LA  +    +V  LC  GAD  +             + PLWVAL     DIA  LV  G D   W        +QTLLHR I E  E+ A FLI   CD         P       E      +G TPLH+A   GLE+VV+ LL   + +VN+Q+A G T LH+A+  +H+ ++  LL+   +L L  RD QG TPF  AM   N +AA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V+AN+N RV+D+   TPLHLA   G  E ++R+L+LAGAN+   T  +Q  LHLA   +   I S L+EN    S  D+     LHLAV  G +++++ LL  SS   ++ NL+G++ +H+L    +EN   IF L L+  PE+P+D+ D  G+T L L  +K N  L  A++  GA LG  N++G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C +CS  E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  544 TPLHLAIYHNHPEVVAVFLEQKANALNGVNNLQIIPDFSLKDSKEQTVLGLALWTGM----HKIAAQLLGSG---AAINERSSDGQTLLHAAILKRNSDGALFLLEHNADINIRTAEGQTPLQLAIRQQLPLVVDALCTRGADMTVRDPAG--------DPPLWVALQGGNDDIASTLVRHGCDSTCWGPG-PGGCQQTLLHRAIDENNEKIACFLIRSDCD------RDGPRRPGLKGEGQEEARDGQTPLHLAATWGLEAVVQCLLEY-RANVNMQDAEGRTPLHIAISNQHDVIIALLLS-HPELRLGARDRQGQTPFACAMTYKNNRAADAILKREPTAAEQVDNKGRNFLHVAVQNSDIESVLFLISVSANVNSRVQDSTGLTPLHLAT-QGGSEIIVRNLLLAGANVRELTKNRQTALHLAAQLDLPSICSVLIENSTDFSACDDNGNNALHLAVMHGRLNVVRVLLTESSIDAEAFNLRGQSPMHVLGQYGKENAAAIFELFLECMPEYPLDKPDIEGHTVLLLAYMKGNGNLCRAVVRAGARLGLTNSQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECAAKFGVTTRKHHCRHCGRLLCNRCSAKEIPIIKFDLNKPVRVCDICFDVLTLG 1165

HSP 2 Score: 198.749 bits (504), Expect = 9.053e-52
Identity = 101/325 (31.08%), Postives = 189/325 (58.15%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYE-ILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLAN 1039
            L KH  LL+QEY K+  K    + +  +L   SG     D+F   L   V  LY+ + +SD+ +KL++  +PGH+ +F A    W+ S +++ + ++L   ++ +   +++W+Y ++++     E  L +LMK+  ++ L  L+ R E   +S V+  NCI +Y+ A E    +L ++C+ +I ++W++ +  DF  + A +   + ++++++PLH+A+KA R+DVVFLY+ E  SQL + ++      +L L+LAL  +   +  TL+   A++   ++ G +LLH+AI R DEFS  FLI++G   N  +    +TP+ L+++
Sbjct:    9 LQKHLALLRQEYVKLQQKLTETERRCAHLAAASGQDERADDFISRLLAFVADLYRSELYSDLQVKLKEQAMPGHKFVFAARSDLWSMSSMASSDTLDLSGIDEEVAVAMLRWVYTEDVDTAGKGEAFLTELMKLGSQYKLTPLRERSEKAIMSSVTVRNCIRYYQTAEELGATSLLNYCAEIIASHWDDLRAEDFSSITAPLLYKMFKSKTDFPLHQAIKAEREDVVFLYLIEYDSQLPDKLDEADLAGKLPLELALERRLESIATTLVTHRADVERPNSEGCTLLHRAITRGDEFSAAFLIRHGAFANAATVLGQETPLHLVSS 333

HSP 3 Score: 77.0258 bits (188), Expect = 2.626e-14
Identity = 101/445 (22.70%), Postives = 175/445 (39.33%), Query Frame = 2

Query: 2414 SLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNI------------TSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADV--------DMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLG---RNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQ----------YTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGA-STSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNN 3646
            SLL  A   G+  A  FL+  G  IN  +    TPL  A       +   L   GA+PN             T +++  +  +    PL +A+ +   ++  + +E  A+          +     KD+ EQT+L   +     + A  L+  G                     N    +G T LH A           LL  N  D+N++ A G T L LA++ +   V+  L       ++++RD  G  P   A++  N   A +++++   +       G   +  LH A+   N +   FLI+ + + +   +   +           TPLHLA   G  E +++ L+   AN+  +  E +  LH+A+ ++   II+ LL +       +D + +TP   A+   N      +L    T  +  + KG N LH+   N
Sbjct:  458 SLLQRAAAAGSESATLFLVAHGASINHTNSRGETPLHTACHFGLAQLTAELLHRGANPNAQTGPAYAPSQSQTPSLVPSDDEMHAQTPLHLAIYHNHPEVVAVFLEQKANALNGVNNLQIIPDFSLKDSKEQTVLGLALWTGMHKIAAQLLGSGAAI------------------NERSSDGQTLLHAAILKRNSDGALFLLEHNA-DINIRTAEGQTPLQLAIRQQLPLVVDALCT--RGADMTVRDPAGDPPLWVALQGGNDDIASTLVRHGCDSTCWGPGPGGCQQTLLHRAIDENNEKIACFLIRSDCDRDGPRRPGLKGEGQEEARDGQTPLHLAATWGL-EAVVQCLLEYRANVNMQDAEGRTPLHIAISNQHDVIIALLLSHPELRLGARDRQGQTPFACAMTYKNNRAADAILKREPTAAEQVDNKGRNFLHVAVQN 880

HSP 4 Score: 67.781 bits (164), Expect = 1.887e-11
Identity = 115/459 (25.05%), Postives = 185/459 (40.31%), Query Frame = 2

Query: 2639 PLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQ-TLLHRTILEMKEQAANFLISRG--CDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAME-----------------------LSNQ-KAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGAN--------------------IANETIEKQNLLHLAVIHERVYIISFLLENGAST-------------SHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILH--ILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEG 3829
            PL +AL      IA  LV   ADV+      + N E  TLLHR I    E +A FLI  G   +  + +  + P + +S+  ++     G              ++ N L     + N Q+++G T LH A+   +EAV + LL  K +++L +R+  G T    A+                         S+Q  AAR I +     A +I   G + L  A    +  A  FL+   A++N    ++   TPLH A   G  + L   L+  GAN                     +++ +  Q  LHLA+ H    +++  LE  A+              S +D+K +T L LA+  G   +   LL  S   I  ++  G+ +LH  IL  N   +G +    +L+H  +  +  + A G T L L   +    +  AL  +GA +   +  G
Sbjct:  260 PLELALERRLESIATTLVTHRADVE------RPNSEGCTLLHRAITRGDEFSAAFLIRHGAFANAATVLGQETPLHLVSSRSAHEASGPGTV------------LIANALLEAGANPNTQDSSGRTPLHRAIVAENEAVFSLLLQCK-QIDLELRNRDGDTALWLALRCPVAEEPGWPEGQAGQHALNGDAFSSQCLAARLIARGSNADASDIKT-GNSLLQRAAAAGSESATLFLVAHGASIN--HTNSRGETPLHTACHFGLAQ-LTAELLHRGANPNAQTGPAYAPSQSQTPSLVPSDDEMHAQTPLHLAIYHNHPEVVAVFLEQKANALNGVNNLQIIPDFSLKDSKEQTVLGLALWTGMHKIAAQLLG-SGAAINERSSDGQTLLHAAILKRN--SDGAL---FLLEHNADINI--RTAEGQTPLQLAIRQQLPLVVDALCTRGADMTVRDPAG 687

HSP 5 Score: 59.6918 bits (143), Expect = 4.810e-9
Identity = 73/259 (28.19%), Postives = 106/259 (40.93%), Query Frame = 2

Query: 2891 IEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKA--------ARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLI----QVNANLNIRVKDAFQYTPLHLAIIS--GAPED----------------LIRSLILAGANIANETIEKQN-LLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLL 3574
            + G  PL +A +  LES+   L++ ++ DV   N+ GCT LH A+    E     L+      N +    Q  TP H     S  +A        A ++L+       + D+ GR  LH A+   N EAV+ L+    Q++  L  R  D   +  L   +    G PE                 L   LI  G+N     I+  N LL  A          FL+ +GAS +H +++ ETPLH A   G   L   LL
Sbjct:  255 LAGKLPLELALERRLESIATTLVT-HRADVERPNSEGCTLLHRAITRGDEFSAAFLIRHGAFANAATVLGQ-ETPLHLVSSRSAHEASGPGTVLIANALLEAGANPNTQ-DSSGRTPLHRAIVAEN-EAVFSLLLQCKQIDLELRNRDGDTALWLALRCPVAEEPGWPEGQAGQHALNGDAFSSQCLAARLIARGSNADASDIKTGNSLLQRAAAAGSESATLFLVAHGASINHTNSRGETPLHTACHFGLAQLTAELL 509

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 134.035 bits (336), Expect = 5.642e-32
Identity = 144/546 (26.37%), Postives = 247/546 (45.24%), Query Frame = 2

Query: 2270 LMNDYAGESPFTLCLWNGL--ISVCDKIFERLIKTDF--KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAG--ADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTI---STMENKNPSNSISNYESNNHYIE--GNTPLHMACQMGLESVVKNLLSSN-KIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF 3868
            LM+   G      C  NGL  + +  K     + T+   + +EID       + LH+A   G  + V+ L++ G +IN +S N  TPL +A ++++++IV+ L  +GA+     ++ +++GF     PL VAL      +  +L+E+     V + ++H     + T     +L+  E  A+     G   +   +   N N +  + N  +   +    G TPLH+A + G  ++VK LL    KID   ++  G T LH A +  HE V+  LL     +    ++  G +P H A +  +    + +L       D  +D L    LHVA    +      L+      N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + ++  LL+NGAS++  + + ETPLH+A R G ++++K LL  S   +  K  + +  LHI S   +   IV   L     P  P     A G+T L+  + + +  +   LL  GA +     +GFT     HI+ ++
Sbjct:   27 LMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGAN----QSVATEDGF----TPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQ-HEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRD--GLTPLHCAARSGHEKVIEMLLERDAPILAKTKN--GLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYL--TPLHVAAHCGHYRVAKLLLDRGGEPNARALNGF--TPLHIACKKNRIK-VMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLL-QSGARVGVKAREDQTPLHIASRLGKAE-IVQLLLQRGSDPNAPT----ASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPL---HIASKY 545

HSP 2 Score: 125.176 bits (313), Expect = 2.758e-29
Identity = 137/565 (24.25%), Postives = 230/565 (40.71%), Query Frame = 2

Query: 2132 KGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITS-------------------NIISQEGF------IELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLC 3751
            +G K+++    T D  TP H A ++ + K+I + +  D        L     G SP  +      ++    +  R        + +D + +D  + LH+A   G+    + L+  G + N R++N  TPL +A +K+ I ++ +L   GA  + T+                    ++ Q G       +    PL +A    + ++   L+++GA V +     K   +QT LH      K +    L+ RG D                   N     G+TPL+ A + G    V +LL  N  D++     G T LH+A K+    V T LL      +  +    G TP H A    +QK A  +L           N G   LH+A +    E    L+++ A  N+  +      PLHLA   G   D++  L+   A+I+  T      +HLA   ++V +   L ++ A  +       TPLH+A   GN+ ++  LL N +  + +K   G   LH      ++    + + +L H  E   +E  A GNTAL + 
Sbjct:  260 RGAKIDTK---TRDGLTPLHCAARSGHEKVIEMLLERD-----APILAKTKNGLSPLHMATQGEHLACVQLLLGR-------QAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGV-----KAREDQTPLHIASRLGKAEIVQLLLQRGSD------------------PNAPTASGSTPLYFASREG-HGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKN-GYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGV--APLHLAAQEGH-ADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRA-LVNAKTRNGYTPLH---QAAQQGHTHVVNALLQH--EASPNELTANGNTALAIA 775

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 132.494 bits (332), Expect = 1.836e-31
Identity = 143/553 (25.86%), Postives = 251/553 (45.39%), Query Frame = 2

Query: 2270 LMNDYAGESPFTLCLWNGL--ISVCDKIFERLIKTDF--KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAG--ADVDMWSIHYKDNYEQTLLHRTILEMKEQA---ANFLISRGCDTIST-------MENKNPSNSISNYESNNHYIE--GNTPLHMACQMGLESVVKNLLSSN-KIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF 3868
            LM+   G      C  NGL  + +  K     + T+   + +EID       + LH+A   G  + V+ L++ G +IN +S N  TPL +A ++++++IV+ L  +GA+     ++ +++GF     PL VAL      +  +L+E+     V + ++H     + T     +L+ +  A   +  ++++  ++  T         N N +  + N  +   +    G TPLH+A + G  ++VK LL    KID   ++  G T LH A +  HE V+  LL     +    ++  G +P H A +  +    + +L       D  +D L    LHVA    +      L+      N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + ++  LL+NGAS++  + + ETPLH+A R G ++++K LL  S   +  K  + +  LHI S   +   IV   L     P  P     A G+T L+  + + +  +   LL  GA +     +GFT     HI+ ++
Sbjct:   26 LMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGAN----QSVATEDGF----TPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRD--GLTPLHCAARSGHEKVIEMLLERDAPILAKTKN--GLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYL--TPLHVAAHCGHYRVAKLLLDRGGEPNARALNGF--TPLHIACKKNRIK-VMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLL-QSGARVGVKAREDQTPLHIASRLGKAE-IVQLLLQRGSDPNAPT----ASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPL---HIASKY 552

HSP 2 Score: 122.479 bits (306), Expect = 2.317e-28
Identity = 140/565 (24.78%), Postives = 233/565 (41.24%), Query Frame = 2

Query: 2132 KGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITS----------------NIIS---QEGF------IELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLC 3751
            +G K+++    T D  TP H A ++ + K+I + +  D        L     G SP  +      ++    +  R        + +D + +D  + LH+A   G+    + L+  G + N R++N  TPL +A +K+ I ++ +L   GA  + T+                N++    Q G       +    PL +A    + ++   L+++GA V +     K   +QT LH      K +    L+ RG D                   N     G+TPL+ A + G    V +LL  N  D++     G T LH+A K+    V T LL  KY  +   +   G TP H A    +QK A  +L           N G   LH+A +    E    L+++ A  N+  +      PLHLA   G   D++  L+   A+I+  T      +HLA   ++V +   L ++ A  +       TPLH+A   GN+ ++  LL N +  + +K   G   LH      ++    + + +L H  E   +E  A GNTAL + 
Sbjct:  267 RGAKIDTK---TRDGLTPLHCAARSGHEKVIEMLLERD-----APILAKTKNGLSPLHMATQGEHLACVQLLLGR-------QAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGV-----KAREDQTPLHIASRLGKAEIVQLLLQRGSD------------------PNAPTASGSTPLYFASREG-HGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLE-KYA-SADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKN-GYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGV--APLHLAAQEGH-ADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRA-LVNAKTRNGYTPLH---QAAQQGHTHVVNALLQH--EASPNELTANGNTALAIA 780

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.457 bits (267), Expect = 1.257e-23
Identity = 130/542 (23.99%), Postives = 231/542 (42.62%), Query Frame = 2

Query: 2171 DLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLK 3796
            D  TP H A ++ + +++ + +           L     G SP  +      +  C ++  +        + +D I +D  + LH+A   G+    + L+  G + NVR++N  TPL +A +K+ I ++ +L   GA    +   +++ G      P+ V+      +I  IL++ GA  +  ++  +          T L M  +A    + R     S + N    ++ +  E         TPLH+A ++G   +V+ LL  +    +   + G T LH+A +  HE V   LL  ++  +L++   +G TP H A +    + A  +LQ    + D     G   LHVA    N++    L+   A+ +   K+   YTPLH+A      E +  +L+  GA     T +    LHL        + S LL   A  +H      +PLHLA +   V++ + L+ + +    +  L G   L +    C    I + + +L H  +  V+ K   G T L   A + ++ + V LLLK
Sbjct:    5 DGLTPLHCAARSGHEQVVEILL-----EQGAPILAKTKNGLSPLHMATQGDHVE-CVQVLMQY------RAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGA----SIEAVTESGLT----PMHVSAFMGNLNIVLILLQGGASPNATNVRGE----------TALHMAARAGQTEVVR-----SLLRNGAQVDAKAREE--------QTPLHIAARLGKLEIVQ-LLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILL--EHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRF-ASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNG--YTPLHIAAKKDQLE-IATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKL-GYTPLIV---ACHYGNIKMVNFLLQHGAD--VNSKTKNGYTPLHQAAQQGHTHI-VNLLLK 489

HSP 2 Score: 88.1965 bits (217), Expect = 9.323e-18
Identity = 82/294 (27.89%), Postives = 136/294 (46.26%), Query Frame = 2

Query: 2999 GCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLIL---AGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF 3868
            G T LH A +  HE V+  LL     +    ++  G +P H A +  + +  + ++QY     D  +D L    LHVA    +      L+   AN N+R  + F  TPLH+A      ++ IR + L    GA+I   T      +H++     + I+  LL+ GAS +  + + ET LH+A R G  ++++ LL N +  + +K  + +  LHI +   R   + I  L+L H      D   + G T L + A + +  +   LL  GASL     +GFT     H++ ++
Sbjct:    6 GLTPLHCAARSGHEQVVEILLEQGAPILAKTKN--GLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYL--TALHVAAHCGHYRTAKVLLDKGANPNVRALNGF--TPLHIA----CKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQ-VDAKAREEQTPLHIAA---RLGKLEIVQLLLQHMAS--PDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPL---HVASKY 280

HSP 3 Score: 87.8113 bits (216), Expect = 1.233e-17
Identity = 93/349 (26.65%), Postives = 152/349 (43.55%), Query Frame = 2

Query: 2885 HYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPK---------YKLNLSIRDHQGH----------------------TPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLA-NSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            H  +G TPLH A + G E VV+ LL      +  +   G + LH+A +  H   +  L+  +         Y   L +  H GH                      TP H A + +  +    +L+Y   + + +   G   +HV+    N   V  L+Q  A+ N    +    T LH+A  +G  E ++RSL+  GA +  +  E+Q  LH+A    ++ I+  LL++ AS     +   TPLH+A R G+ D+   LL   +S  + +K  KG   LH+ S   +   + + SL+L  +     D     G T L + +  DN ++ + LL +GAS       G+T
Sbjct:    2 HRQDGLTPLHCAARSGHEQVVEILLEQGA-PILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYG-ASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPN--ATNVRGETALHMAARAGQTE-VVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTK--KGFTPLHVASKYGK---MEVASLLLQRFAS--PDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYT 338

HSP 4 Score: 55.8398 bits (133), Expect = 7.457e-8
Identity = 61/259 (23.55%), Postives = 108/259 (41.70%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNL 2956
            TP H+A    N K+  L +  D+G +      N Y   +P  +      + +   + E         +E + I     + LHL  ++G+ +    L+    D+N  + + ++PL LA ++  +++  IL   GA  N T+ +    G+     PL VA +     + + L++ GADV+  +   K+ Y  T LH+   +      N L+  G                     N+  + GNT L +A ++G  SVV  L
Sbjct:  305 TPLHVASHYDNQKVALLLL--DQGASPHATAKNGY---TPLHIAAKKDQLEIATTLLEY-------GAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKL----GYT----PLIVACHYGNIKMVNFLLQHGADVNSKT---KNGY--TPLHQAAQQGHTHIVNLLLKCGA------------------RPNDVTVNGNTALAIARRLGYISVVDTL 520

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 104.76 bits (260), Expect = 7.092e-23
Identity = 112/405 (27.65%), Postives = 173/405 (42.72%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAG-ANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILH 3631
            LH+A KK  I  ++ L+K G  I   + + +TP+ ++    N++IV IL   GA PN T+        +     L +A    + ++   L+  GA VD      K   EQT LH      K +    L+             +P  + SN         G TPLH+A + G E V   LL  +   + V    G T LH+A K+    V + LL      + + ++  G TP H A    NQK A  +L           N G   LH+A +    E    L++  A  N   +      PLHL    G  +  + SL+LA  A++ + T    + LHLA   ++V +   L+++GA  +       TPL +A   GN+ ++  LL + +  + SK   G   LH
Sbjct:   19 LHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATN--------VRGETALHMAARAGQTEVVRSLLRNGAQVDA-----KAREEQTPLHIAARLGKLEIVQLLLQ---------HMASPDAATSN---------GYTPLHVAAREGHEDVTAILL-EHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKN--GLTPLHVASHYDNQKVALLLLDQGASPHATAKN-GYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGV--APLHLGAQEGHAD--VASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGA-DVNSKTKNGYTPLH 383

HSP 2 Score: 93.2041 bits (230), Expect = 2.725e-19
Identity = 113/444 (25.45%), Postives = 194/444 (43.69%), Query Frame = 2

Query: 2465 LIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLK 3796
            L+  G + NVR++N  TPL +A +K+ I ++ +L   GA    +   +++ G      P+ V+      +I  IL++ GA  +  ++  +          T L M  +A    + R     S + N    ++ +  E         TPLH+A ++G   +V+ LL  +    +   + G T LH+A +  HE V   LL  ++  +L++   +G TP H A +    + A  +LQ    + D     G   LHVA    N++    L+   A+ +   K+   YTPLH+A      E +  +L+  GA     T +    LHL        + S LL   A  +H      +PLHLA +   V++ + L+ + +    +  L G   L +    C    I + + +L H  +  V+ K   G T L   A + ++ + V LLLK
Sbjct:    1 LLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGA----SIEAVTESGLT----PMHVSAFMGNLNIVLILLQGGASPNATNVRGE----------TALHMAARAGQTEVVR-----SLLRNGAQVDAKAREE--------QTPLHIAARLGKLEIVQ-LLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILL--EHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRF-ASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNG--YTPLHIAAKKDQLE-IATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKL-GYTPLIV---ACHYGNIKMVNFLLQHGAD--VNSKTKNGYTPLHQAAQQGHTHI-VNLLLK 399

HSP 3 Score: 89.3521 bits (220), Expect = 4.418e-18
Identity = 104/425 (24.47%), Postives = 170/425 (40.00%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVD------MWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLA 3436
            TP H++    N+ I+ + +      N  N       GE+   +    G   V   +     + D K  E       EQ+ LH+A + G +E VQ L++     +  + N  TPL +A  + + D+  IL   GA   +T    +++GF     PL VA    + ++A +L++  A  D      +  +H   +Y+            ++ A  L+ +G    +T +N                  G TPLH+A +     +   LL     + N     G   LHL  +  H  V + LL     +N + +   G +P H A +      A  IL  H    +    LG   L VA    N + V FL+Q  A++N + K+   YTPLH A   G    ++  L+  GA   + T+     L +A
Sbjct:   50 TPMHVSAFMGNLNIVLILLQGGASPNATN-----VRGETALHMAARAGQTEVVRSLLRNGAQVDAKARE-------EQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVT----TKKGFT----PLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDN-----------QKVALLLLDQGASPHATAKN------------------GYTPLHIAAKKDQLEIATTLLEYGA-ETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKS--GLSPLHLAAQEDKVNVAE-ILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNG--YTPLHQAAQQGH-THIVNLLLKCGARPNDVTVNGNTALAIA 418

HSP 4 Score: 78.1814 bits (191), Expect = 1.124e-14
Identity = 72/253 (28.46%), Postives = 121/253 (47.83%), Query Frame = 2

Query: 3080 NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLA-NSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            N ++R   G TP H A + +  +    +L+Y   + + +   G   +HV+    N   V  L+Q  A+ N    +    T LH+A  +G  E ++RSL+  GA +  +  E+Q  LH+A    ++ I+  LL++ AS     +   TPLH+A R G+ D+   LL   +S  + +K  KG   LH+ S   +   + + SL+L  +     D     G T L + +  DN ++ + LL +GAS       G+T
Sbjct:    7 NPNVRALNGFTPLHIACKKNRIRVMELLLKYG-ASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPN--ATNVRGETALHMAARAGQTE-VVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTK--KGFTPLHVASKYGK---MEVASLLLQRFAS--PDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYT 248

HSP 5 Score: 68.1662 bits (165), Expect = 1.439e-11
Identity = 59/205 (28.78%), Postives = 99/205 (48.29%), Query Frame = 2

Query: 3263 LIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRS---LILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF 3868
            L+   AN N+R  + F  TPLH+A      ++ IR    L+  GA+I   T      +H++     + I+  LL+ GAS +  + + ET LH+A R G  ++++ LL N +  + +K  + +  LHI +   R   + I  L+L H      D   + G T L + A + +  +   LL  GASL     +GFT     H++ ++
Sbjct:    1 LLDKGANPNVRALNGF--TPLHIA----CKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQ-VDAKAREEQTPLHIAA---RLGKLEIVQLLLQHMAS--PDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPL---HVASKY 190

HSP 6 Score: 55.4546 bits (132), Expect = 9.544e-8
Identity = 61/259 (23.55%), Postives = 108/259 (41.70%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNL 2956
            TP H+A    N K+  L +  D+G +      N Y   +P  +      + +   + E         +E + I     + LHL  ++G+ +    L+    D+N  + + ++PL LA ++  +++  IL   GA  N T+ +    G+     PL VA +     + + L++ GADV+  +   K+ Y  T LH+   +      N L+  G                     N+  + GNT L +A ++G  SVV  L
Sbjct:  215 TPLHVASHYDNQKVALLLL--DQGASPHATAKNGY---TPLHIAAKKDQLEIATTLLE-------YGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKL----GYT----PLIVACHYGNIKMVNFLLQHGADVNSKT---KNGY--TPLHQAAQQGHTHIVNLLLKCGA------------------RPNDVTVNGNTALAIARRLGYISVVDTL 430

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Yeast
Match: VPS27 (Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289])

HSP 1 Score: 74.3294 bits (181), Expect = 6.632e-14
Identity = 42/114 (36.84%), Postives = 58/114 (50.88%), Query Frame = 2

Query: 3743 FLCALKDNSRLG--VALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCF 4078
               A K++S+L     +  K  S G    E  TL NS          + DS +   +W+D + C  C  KFS+ NRKHHCR CG + C + S N +P+    I +PVRVC+ CF
Sbjct:  121 LYVAFKNDSQLNYVAKVYDKLISRGIKFPEKLTLSNS-------PTAMFDSKTPA-DWIDSDACMICSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSCF 226

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464])

HSP 1 Score: 65.855 bits (159), Expect = 3.508e-12
Identity = 51/153 (33.33%), Postives = 72/153 (47.06%), Query Frame = 2

Query: 2900 NTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNL-SIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD--EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGA 3349
            N PLH AC       V+ LL S    +  ++  G   LH +V F+   + + LL+    +NL    D  G TPFH A  + N +  +S+    P   D  +I N G   LH+AV     E   FLI+  A  ++R+KD F   PLH A   G+
Sbjct:    3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYD-RPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGA--SVRIKDKFNQIPLHRAASVGS 152

HSP 2 Score: 56.6102 bits (135), Expect = 4.222e-9
Identity = 51/190 (26.84%), Postives = 84/190 (44.21%), Query Frame = 2

Query: 3113 PFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIR-VKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNL--LHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGEN-ILHILSNNCRENGIVI 3670
            P H A   +     + +L   P    + D  GR  LH +V     E   FL+    N+N+    D   +TP H+A   G  E +++SL           I  Q +  LHLAV  +   +  FL+ENGAS   +D   + PLH A   G++ LI+ L     + +  ++ +G   + H L+    +  +++
Sbjct:    5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLE-VVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLL 193

HSP 3 Score: 56.225 bits (134), Expect = 6.413e-9
Identity = 50/182 (27.47%), Postives = 84/182 (46.15%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDY---AGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEA-GADVDM 2716
            P H +V  +  +I +  +   E  N     ++DY   +G +PF +    G + V   +++R +K D     ++KI     + LHLAV K   E  QFLI+ G  + ++      PL  A    ++ ++ +LC  G       N   ++G+     PL+ AL     D A +LVE  GA+ D+
Sbjct:   39 PLHWSVSFQAHEITSFLLSKMENVN-----LDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPD-----LNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKS---AVNWQDKQGW----TPLFHALAEGHGDAAVLLVEKYGAEYDL 203

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Yeast
Match: HOS4 (Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374])

HSP 1 Score: 53.1434 bits (126), Expect = 2.900e-7
Identity = 26/62 (41.94%), Postives = 41/62 (66.13%), Query Frame = 2

Query: 2414 SLLHLAVKKGNIEAVQFLIKIGCDINVRSINKM--TPLLLATEKSNIDIVRILCLSGADPNI 2593
            + LH A  +G+IE V+ LI+ G D+N++SI     TPL+ A+   ++D+V+ L  +GADP I
Sbjct:  366 TALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTI 427

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Nematostella
Match: EDO39873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8R8])

HSP 1 Score: 177.948 bits (450), Expect = 7.807e-48
Identity = 108/337 (32.05%), Postives = 181/337 (53.71%), Query Frame = 2

Query:   53 MTDET----LLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVN-VISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIP 1048
            M DE     L +H  LL++EY K+ NK   ++ KY ++   S     E++F   L K V  LY    +SDI++      I  H+ +  A    W   DL+   E+ L +   ++G  ++KW+Y  +    +    L  L+  ++++ LK L+ RCE   +S V+  NCI FY+ A +   + L+ +C+ +I  +W++ +  DF G+ A +  ++ +++S YPLH  ++ +R+DV+FL++ E  SQL   +N V     E+ L +ALS K   +  TL+    +++ VD+ G  LLHKAI   DEFS  FLI+NG  ++  +     TP+ L A+  P
Sbjct:    1 MADEGQVAKLERHLGLLREEYVKLQNKLVEMEHKY-SIAKASAGQGEENSFVSRLLKTVADLYDKDLYSDITVSFGGQKIKAHKFVLAARSDHWCSRDLNEVTELELSDVSVDVGLTLMKWVYTDKAQIPKEESFLINLVHASNKYRLKDLRLRCEKILMSSVTVSNCIKFYQTAEDIGAKELQKYCAEIISNHWHDLKTEDFVGISAPLLYEMFKSKSTYPLHLTIRHHREDVLFLFLIEFNSQLPGKLNEVDPTTGEVPLHIALSEKLDSIARTLVGHGCDVDMVDSSGNCLLHKAISHGDEFSSTFLIKNGARVSAANHAEKVTPLHLTASYRP 336

HSP 2 Score: 63.1586 bits (152), Expect = 4.099e-10
Identity = 60/208 (28.85%), Postives = 100/208 (48.08%), Query Frame = 2

Query: 2639 PLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTIST--MENKNPSNSISNYESNNHYIEGN--TPL---HMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAM-----ELSNQKAARSILQYHPQAADEIDNL-GRNFLH 3223
            PL +AL+     IA  LV  G DVDM      D+    LLH+ I    E ++ FLI  G    +    E   P +  ++Y     ++ G+  +P    HM    G+  +  +LL     + + Q+  G T LH A++ +++ V+  LLN + KLNL +RD QG  P   A+     +  ++++  + L  H  +AD ++ + G + LH
Sbjct:  260 PLHIALSEKLDSIARTLVGHGCDVDM-----VDSSGNCLLHKAISHGDEFSSTFLIKNGARVSAANHAEKVTPLHLTASYRP---WMAGSASSPAGANHMTSAEGMARIA-SLLIDKGANTDAQDLAGRTPLHRAIEAKNDKVMNILLN-RSKLNLELRDKQGRVPLWLALSCDSFDSMDEESLAAKLVKHGASADAVNTVTGDSLLH 457

HSP 3 Score: 52.373 bits (124), Expect = 9.461e-7
Identity = 59/207 (28.50%), Postives = 89/207 (43.00%), Query Frame = 2

Query: 3011 LHLAVKFRHEAVLTHLL---NPKY--KLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKG 3616
            LHL ++   E VL   L   N +   KLN  +    G  P H A+       AR+++  H    D +D+ G   LH A+   +  +  FLI+  A ++     A + TPLHL   S  P     +   AGAN            H+        I S L++ GA+T  QD    TPLH A+   N  ++  LL  S   ++ ++ +G
Sbjct:  222 LHLTIRHHREDVLFLFLIEFNSQLPGKLN-EVDPTTGEVPLHIALSEKLDSIARTLVG-HGCDVDMVDSSGNCLLHKAISHGDEFSSTFLIKNGARVSA-ANHAEKVTPLHLT-ASYRPWMAGSASSPAGAN------------HMTSAEGMARIASLLIDKGANTDAQDLAGRTPLHRAIEAKNDKVMNILLNRSKLNLELRDKQG 412

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Nematostella
Match: EDO39875 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8S0])

HSP 1 Score: 167.548 bits (423), Expect = 1.133e-47
Identity = 78/165 (47.27%), Postives = 109/165 (66.06%), Query Frame = 2

Query: 3611 KGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEP-NWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNGKF 4102
            +G+N LH+L+   ++N + IF +     PE+P++  DA GNTALFL  +   +RL   LL  G+SL   N  G ++FN+E  +++ +  LLD L   P  W DG+ C+ C  KFSIK+RKHHCRHCGRL+C KCS  ++PIIK+ + KPVRVC+VCF  L +G F
Sbjct:    9 RGQNPLHVLAQYAKDNAVAIFEIFRQSMPEYPMNAVDAEGNTALFLAYVNGAARLCRELLRGGSSLATVNKYGLSIFNAEVPTKKLLYTLLDVLQGYPICWSDGDSCYECGMKFSIKHRKHHCRHCGRLLCAKCSCKQIPIIKYELAKPVRVCDVCFEMLTSGAF 173

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Nematostella
Match: EDO44864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUJ2])

HSP 1 Score: 72.0182 bits (175), Expect = 1.933e-13
Identity = 30/64 (46.88%), Postives = 41/64 (64.06%), Query Frame = 2

Query: 3887 SLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCF 4078
            S  S P W +G++C  C  KF    R+HHCR+CG++ C KCS  E  I +F I+K VRVC+ C+
Sbjct:  154 SADSAPAWAEGDVCHMCRVKFGTFIRQHHCRNCGQVFCKKCSSKESIIPQFGIEKEVRVCDPCY 217

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Nematostella
Match: EDO48232 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKE8])

HSP 1 Score: 65.855 bits (159), Expect = 6.575e-11
Identity = 29/71 (40.85%), Postives = 43/71 (60.56%), Query Frame = 2

Query: 3902 PNWL-DGEI--CFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNGKFQ 4105
            P W+ D  +  C  C   F++ NR+HHCR CG++VCG CS N  P+   +  +  RVC++C+  L+ GK Q
Sbjct:  339 PVWIPDARVTMCMLCTDDFTVTNRRHHCRGCGKVVCGSCSDNLAPLTYLDYAQ-ARVCDMCYEVLLRGKEQ 408

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Nematostella
Match: EDO38501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCW3])

HSP 1 Score: 60.8474 bits (146), Expect = 5.808e-10
Identity = 28/63 (44.44%), Postives = 38/63 (60.32%), Query Frame = 2

Query: 3914 DGEICFSCL-CKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNGK 4099
            +   C SC+  KF+  NR+HHCR CG +VCG CS  +  ++     KP+RVC  C+N L N K
Sbjct:  156 EASTCMSCMKTKFTAINRRHHCRKCGAVVCGACSTKKF-LLPAQSSKPLRVCNSCYNTLSNTK 217

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Medaka
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:NCBI gene;Acc:101170537])

HSP 1 Score: 447.203 bits (1149), Expect = 2.733e-135
Identity = 256/650 (39.38%), Postives = 375/650 (57.69%), Query Frame = 2

Query: 2174 LCTPTHLAVKTKNIKIINLFI------FHDEGRNKV--NWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLN-PKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNG 4096
            L TP H+A+  K+  ++++ +       H     ++  ++ + D   ++   L LW G+ ++  ++           + I+  + + Q+LLH+A+++ + ++  FL++   DINVR+    T L LA       +V  +C  GAD     +++  +G    + PLW+AL N   DIA  LV  G D   WS        QTLLHR + E  E +A FLI  GCD  S      P     N E +    +G TPLH+A   GLE VV+ LL     +VN Q+A G T +H A+  +H  ++  L++ P  +LN  IRD QG TPF  AM   N KAA +IL+  P AA+++DN GRNFLHVAVQ  + E+V FLI V AN+N RV+DA + TPLHLA+ +G+ E ++R+L+LAGA +   T  +Q  LHLA   +   I S LLEN    + +D      LHLAV  G ++ ++ LL  S+   ++ NL+G++ +HIL +  +EN   IF L L+  PE+P+D+ D  GNT L L  +K N+ L  A++  GA LG  NN+G  +FN +  ++Q + +LLD LS EP W DG  C+ C  KF +  RKHHCRHCGRL+C KCS+ E+PIIKF++ KPVRVC++CF+ L  G
Sbjct:  540 LQTPLHMAISHKHPDVVSVILEQKANALHATNNLQIIPDFSLKDAMDQTVLGLALWTGMHNIAAQLLG-------SGASINDTMSNGQTLLHMAIQRQDSKSALFLLEHQADINVRTQEGQTALQLAISNKLPLVVDAICTRGAD----MSVVDDKG----DPPLWLALENGLEDIASTLVRHGCDSTCWSPG-PSGCMQTLLHRAVDENNEVSACFLIRSGCDVNS------PRRPGPNGEGDEEARDGQTPLHLASNWGLEEVVQCLLEFGA-NVNTQDAEGRTPIHAAISNQHNVIIQLLISHPDIRLN--IRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDAAKLTPLHLAVQAGS-EIIVRNLLLAGAKVNEVTKHRQTALHLAAQQDLATICSVLLENSIDFAAEDENGNNALHLAVMHGRLNNVRVLLTESNVDAEAFNLRGQSPMHILGHYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGITNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECAAKFGVTTRKHHCRHCGRLLCHKCSLKEIPIIKFDLNKPVRVCDICFDVLTLG 1163

HSP 2 Score: 227.639 bits (579), Expect = 3.791e-60
Identity = 171/585 (29.23%), Postives = 287/585 (49.06%), Query Frame = 2

Query:   68 LLKHFNLLQQEYHKINNKYQSLKTKYDNLILL-----SGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTF-------MLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPI 1786
            L KH  LL+QEY K+  K    + +   L        S  P+  D F   L +IV SLYK +++SD+++K+       H+ +  A    W+ ++L+   +++L + +  +   ++ W+Y  +L  +++   L  LMK+A+   L+ L+ RCE G +S V+  NCI FY+ A E     L ++C  +I ++W++ +  DF  + A +   ++++++ YPLH+A+K  R+DVVFLY+ E  SQL   +N +  + +L LDLALS K   +  TL+ + A+++ VD  GWSLLHKAIQR DEF+  FLI++   +N  +    +TP+ L+ +  P    A+ ++ +  I + L++ GA+                 NM  N   RT L  A++SGNE V + +L   +C  ++            + ++A+  A  +I+++  P          P        F D   +    +F        LI+  ++P    D+ T N ++      G E AA+F L  +  K                   VN  N   ES  H A  N L NL   LLQ GA+PN+  ++ +
Sbjct:    9 LQKHLALLRQEYVKMQQKLADTERRCAVLAAQTSSQGSPGPAAADTFISRLLEIVASLYKQEQYSDLTVKVAGEDFYAHKFVLAARSDIWSLANLATTSQLDLSDCKPEVAVAMLLWVYTDDLELSEDDAFLIDLMKLANRFQLQMLRERCEKGVMSSVNVRNCIRFYQTAEELDASTLMNYCGEIIASHWDDLRKEDFSTMSAQLLYKMIKSKTEYPLHKAIKIEREDVVFLYLIEMDSQLPGKLNQLDNNGDLPLDLALSRKLESIATTLVNNKADVDKVDQSGWSLLHKAIQRGDEFASIFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSAQVMSGMARIADALLKAGANP----------------NMQ-NSRGRTPLHEAVVSGNETVFQQLL---QCKQLD------MELKDHEGSTALWLALQYITLSSDP-------SVNP--------FEDDAVIVNGTSFDENGFAAELIKRGSNPDA-PDASTENCLMQRAAQAGNEAAALF-LATHGAK-------------------VNHVNKLGESSLHTACRNGLANLTAELLQQGANPNMQTQKAL 531

HSP 3 Score: 54.299 bits (129), Expect = 1.152e-6
Identity = 56/209 (26.79%), Postives = 95/209 (45.45%), Query Frame = 2

Query: 3011 LHLAVKF-RHEAVLTHLLNPKYKL--NLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENIL 3628
            LH A+K  R + V  +L+    +L   L+  D+ G  P   A+    +  A +++       D++D  G + LH A+Q  +  A  FLI+ +A +N     A + TPLHL + S +P+     ++   A IA+                       LL+ GA+ + Q+++  TPLH AV  GN  + + LL      ++ K+ +G   L
Sbjct:  227 LHKAIKIEREDVVFLYLIEMDSQLPGKLNQLDNNGDLPLDLALSRKLESIATTLVNNKADV-DKVDQSGWSLLHKAIQRGDEFASIFLIRHSAQVNAATVGAVE-TPLHL-VCSFSPKKHSAQVMSGMARIADA----------------------LLKAGANPNMQNSRGRTPLHEAVVSGNETVFQQLLQCKQLDMELKDHEGSTAL 410

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Medaka
Match: ENSORLT00000031565.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458])

HSP 1 Score: 135.576 bits (340), Expect = 1.858e-31
Identity = 143/540 (26.48%), Postives = 234/540 (43.33%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIH---YKDNYEQTLL-----HRTILEMKE--------------QAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLLDSLSSEPN 3907
            + + +D       + LH++   G  E V+ L+K G DIN +S N  TPL +A +++++D+VR L  +G +     +  +++GF     PL +AL      +  IL+E      V + ++H    KD+ +   L     H   ++ K                 A  L++RG     T  N                  G TPLH+A + G  ++V+ LL   ++ID   ++  G T LH A +  HEA +  LL  +    L  R   G +P H A +  + +  + +LQ H    D++       LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G  ++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +        LL  GAS      +GFT     H+  ++    + KLL    + P+
Sbjct:  102 RGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGN----QSTATEDGF----TPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN------------------GITPLHVASKRGNTNMVRLLLDRGSQIDAKTRD--GLTPLHCAARSGHEASVEVLL--EKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ-HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRVK-VMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGA-MVDARAREDQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPL---HVVSKYGSLDVAKLLLQRQAPPD 598

HSP 2 Score: 106.686 bits (265), Expect = 1.227e-22
Identity = 114/424 (26.89%), Postives = 179/424 (42.22%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDH 3691
            LH+A KK  ++ ++ L+K G  I   + + +TP+ +A    +++IV +L  +GA P++ SNI  +         L +A    + ++   L+  GA VD      +   +QT LH      K +    L+             +P  + +N         G TPLH++ + G       LL +     ++    G T LH+  K+    V   LL  +   + + ++  G TP H A    NQK A  +L           N G   LH+A +    +    L+Q  A  N   K     TPLHLA   G   D+   L+  GA I   T      LHLA   +RV +   L+ NGA+  HQ     TPL +A   GN  ++  LL N +    S N K +N    L    ++    I +++L H
Sbjct:  410 LHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDV-SNIRGE-------TSLHMAARAGQAEVVRCLLRNGAMVDA-----RAREDQTPLHIASRLGKTEIVQLLL---------QHMAHPDAATTN---------GYTPLHISAREGQLETASVLLEAGASH-SLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKN--GLTPLHVAAHYDNQKVALLLLDKGASPHTTAKN-GYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGV--TPLHLASQEGH-ADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGA----SVNAKTKNGYTPLHQAAQQGNTHIINVLLQH 791

HSP 3 Score: 99.7525 bits (247), Expect = 1.883e-20
Identity = 138/614 (22.48%), Postives = 252/614 (41.04%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGAD-PNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQY--HPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISG------------APEDLIR------------------SLILAGANIANETIEKQNL--LHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT-LFNSEHISEQFILKLLDSLSSEPNWL 3913
            TP H+A    N+ +  L +        V++   +  G +P  +    G  ++   + +R        S+ID    D  + LH A + G+  +V+ L++ G  +  R+ N ++PL +A +  +++ V+ L    A   ++T + ++          L VA +   + +  +L++  A+ +  +++       T LH    + + +    L+  G    +  E+                  G TP+H+A  MG  ++V  LL  N    +V N  G TSLH+A +     V+  LL     ++   R+ Q  TP H A  L   +  + +LQ+  HP AA      G   LH++ +    E    L++  A+ ++  K  F  TPLH+    G            AP D                     +L+L     +  T  K     LH+A    ++ I + LL+ GA T+    +  TPLHLA + G+ D+   LL +    I      G   LH+ +   +E+ + +  +++ +      D +   G T L +     N+++   LL  GAS+      G+T L  +       I+ +L    ++PN +
Sbjct:  243 TPLHIAAHYGNVNVATLLLNRGAA---VDFTARN--GITPLHVASKRGNTNMVRLLLDR-------GSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTA---------LHVAAHCGHYRVTKLLLDKRANPNARALNGF-----TPLHIACKKNRVKVMELLVKYGASIQAVTES------------------GLTPIHVAAFMGHLNIVL-LLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQ--TPLHIASRLGKTEIVQLLLQHMAHPDAAT---TNGYTPLHISAREGQLETASVLLEAGASHSLATKKGF--TPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAA-LLMSKGAQINVPTKSGLTALHLAA---QEDRVAVAEILVRNGANL--DHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAV 798

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Medaka
Match: ENSORLT00000039458.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458])

HSP 1 Score: 135.576 bits (340), Expect = 2.268e-31
Identity = 143/540 (26.48%), Postives = 234/540 (43.33%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE--AGADVDMWSIH---YKDNYEQTLL-----HRTILEMKE--------------QAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLS-SNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLLDSLSSEPN 3907
            + + +D       + LH++   G  E V+ L+K G DIN +S N  TPL +A +++++D+VR L  +G +     +  +++GF     PL +AL      +  IL+E      V + ++H    KD+ +   L     H   ++ K                 A  L++RG     T  N                  G TPLH+A + G  ++V+ LL   ++ID   ++  G T LH A +  HEA +  LL  +    L  R   G +P H A +  + +  + +LQ H    D++       LHVA    +      L+   AN N R  + F  TPLH+A      + ++  L+  GA+I   T      +H+A     + I+  LL+NGAS    + + ET LH+A R G  ++++ LL N +  + ++  + +  LHI S   R     I  L+L H      D     G T L + A +        LL  GAS      +GFT     H+  ++    + KLL    + P+
Sbjct:   87 RGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGN----QSTATEDGF----TPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN------------------GITPLHVASKRGNTNMVRLLLDRGSQIDAKTRD--GLTPLHCAARSGHEASVEVLL--EKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ-HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGF--TPLHIACKKNRVK-VMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGA-MVDARAREDQTPLHIAS---RLGKTEIVQLLLQHMAH--PDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPL---HVVSKYGSLDVAKLLLQRQAPPD 583

HSP 2 Score: 106.686 bits (265), Expect = 1.524e-22
Identity = 114/424 (26.89%), Postives = 179/424 (42.22%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDH 3691
            LH+A KK  ++ ++ L+K G  I   + + +TP+ +A    +++IV +L  +GA P++ SNI  +         L +A    + ++   L+  GA VD      +   +QT LH      K +    L+             +P  + +N         G TPLH++ + G       LL +     ++    G T LH+  K+    V   LL  +   + + ++  G TP H A    NQK A  +L           N G   LH+A +    +    L+Q  A  N   K     TPLHLA   G   D+   L+  GA I   T      LHLA   +RV +   L+ NGA+  HQ     TPL +A   GN  ++  LL N +    S N K +N    L    ++    I +++L H
Sbjct:  395 LHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDV-SNIRGE-------TSLHMAARAGQAEVVRCLLRNGAMVDA-----RAREDQTPLHIASRLGKTEIVQLLL---------QHMAHPDAATTN---------GYTPLHISAREGQLETASVLLEAGASH-SLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKN--GLTPLHVAAHYDNQKVALLLLDKGASPHTTAKN-GYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGV--TPLHLASQEGH-ADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGA----SVNAKTKNGYTPLHQAAQQGNTHIINVLLQH 776

HSP 3 Score: 99.3673 bits (246), Expect = 2.462e-20
Identity = 138/614 (22.48%), Postives = 252/614 (41.04%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGAD-PNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQY--HPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISG------------APEDLIR------------------SLILAGANIANETIEKQNL--LHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT-LFNSEHISEQFILKLLDSLSSEPNWL 3913
            TP H+A    N+ +  L +        V++   +  G +P  +    G  ++   + +R        S+ID    D  + LH A + G+  +V+ L++ G  +  R+ N ++PL +A +  +++ V+ L    A   ++T + ++          L VA +   + +  +L++  A+ +  +++       T LH    + + +    L+  G    +  E+                  G TP+H+A  MG  ++V  LL  N    +V N  G TSLH+A +     V+  LL     ++   R+ Q  TP H A  L   +  + +LQ+  HP AA      G   LH++ +    E    L++  A+ ++  K  F  TPLH+    G            AP D                     +L+L     +  T  K     LH+A    ++ I + LL+ GA T+    +  TPLHLA + G+ D+   LL +    I      G   LH+ +   +E+ + +  +++ +      D +   G T L +     N+++   LL  GAS+      G+T L  +       I+ +L    ++PN +
Sbjct:  228 TPLHIAAHYGNVNVATLLLNRGAA---VDFTARN--GITPLHVASKRGNTNMVRLLLDR-------GSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTA---------LHVAAHCGHYRVTKLLLDKRANPNARALNGF-----TPLHIACKKNRVKVMELLVKYGASIQAVTES------------------GLTPIHVAAFMGHLNIVL-LLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQ--TPLHIASRLGKTEIVQLLLQHMAHPDAAT---TNGYTPLHISAREGQLETASVLLEAGASHSLATKKGF--TPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAA-LLMSKGAQINVPTKSGLTALHLAA---QEDRVAVAEILVRNGANL--DHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAV 783

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Medaka
Match: ank1b (ankyrin-1 [Source:NCBI gene;Acc:101157380])

HSP 1 Score: 115.931 bits (289), Expect = 1.856e-25
Identity = 130/523 (24.86%), Postives = 242/523 (46.27%), Query Frame = 2

Query: 2384 EIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAG--ADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTI---STMENKNPSNSISNYESNNHYIEGN--TPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAAD-EIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIAN-ETIEKQNL--LHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQF----ILKLLDSLSSEPN 3907
            E++       + LH+A   G  + V  L+  G ++N +S    +PL +A +++++++V+ L  +GA+     ++ +++GF     PL VAL     ++  +L+  G    V + ++H     + T     +L+  +   + L   G   +   +  EN + +  + N  +N ++   N  TPLH+A + G   +V+ LL      ++ Q     T LH A +  H  ++  LL  ++   +  +   G +P H A +  +    R +LQY+ +  D  +D+L    LHVA    +      L+   A  N R  + F  TPLH+A      ++ +RS+ L   + A+ E + +  L  LH+A     + I+  LL+ GAS +  + K+ETPLH+A R G+ ++ + LL N++  + ++    +  LH  +   R     +  L+LDH      D     G+T L + A + +      LL  GA       +GFT     H++ ++    + +LL    + PN
Sbjct:   68 ELEATTKKGNTALHIAALAGQEKVVAELVNYGANVNAQSHKGFSPLYMAAQENHLEVVKFLLENGAN----QSLPTEDGF----TPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ-NDPNPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVMMVRLLLDRGA-QIDAQTKDELTPLHCAARNGHVRIIEILL--EHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHL--TPLHVAAHCGHHRMAKVLLDKGAKANARALNGF--TPLHIA----CKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKNLLQRGASPNASNVKVETPLHMASRAGHCEVAQFLLQNAA-QVDARAKDDQTPLHCAA---RMGHKELVKLLLDHKAN--PDSATTAGHTPLHIAAREGHIHTIRILLDAGAQQVKMTKKGFTPL---HVASKYGKVDVAELLLERGANPN 561

HSP 2 Score: 105.916 bits (263), Expect = 2.578e-22
Identity = 131/528 (24.81%), Postives = 225/528 (42.61%), Query Frame = 2

Query: 2138 RKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHD---EGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRIL----------CLSGADP----------NITSNIISQEGF------IELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYI---------------EGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNL-GRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSS 3586
            R    D Q T D  TP H A +  +++II + + H    + + K         G SP  +      +    ++ +         +EID I +D  + LH+A   G+    + L+  G   N R++N  TPL +A +K+++  + +L            SG  P          NI  N++ Q G       +++  PL +A      ++A  L++  A VD  +   KD+  QT LH       ++    L+    +  S     +    I+  E + H I               +G TPLH+A + G   V + LL     + N     G T LH+AV   +  V+  L++     + + R+  G+TP H A + +  + A  +LQ    A+   ++L G   LH+A Q    + V  LI   AN+N+  K+    TPLHL    G    +  +L+  GA++   +      LH+A  +  + ++ FLL+  A  + +     TPLH A + G+ D++  LL + +
Sbjct:  259 RGAQIDAQ-TKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTK--------NGLSPIHMAAQGDHMDCVRQLLQ-------YNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKNLL-QRGASPNASNVKVETPLHMASRAGHCEVAQFLLQNAAQVDARA---KDD--QTPLHCAARMGHKELVKLLLDHKANPDSATTAGHTPLHIAAREGHIHTIRILLDAGAQQVKMTKKGFTPLHVASKYGKVDVAELLLERGA-NPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSAHSTARN--GYTPLHIAAKQNQIEVASVLLQN--GASPNCESLQGITPLHLASQEGRPDMVAMLISKQANVNLGNKNGL--TPLHLVAQEGH-VGIADTLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNAKTRMGYTPLHQAAQQGHTDIVTLLLKHGA 756

HSP 3 Score: 103.605 bits (257), Expect = 1.014e-21
Identity = 130/493 (26.37%), Postives = 214/493 (43.41%), Query Frame = 2

Query: 2420 LHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVD------MWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSIS--------------NYESNNHYIEGNTPLHMACQMG-LESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            LH+A    N+   Q L+  G ++N    N +TPL +A+ + N+ +VR+L   GA        I  +   EL  PL  A  N    I +IL+E GA +       +  IH     +     R +L+   +          D I T+++  P +  +                ++N   + G TPLH+AC+   + S+  +LL  +   +     +G T LH+A    H  ++ +LL      N S  + +  TP H A    + + A+ +LQ   Q  D      +  LH A +  ++E V  L+   AN +        +TPLH+A   G     IR L+ AGA     T +    LH+A  + +V +   LLE GA+ +       TPLH+AV   N+D++K LL +   +  S    G   LHI +   ++N I + S++L +      + +   G T L L + +    +   L+ K A++   N  G T
Sbjct:  208 LHIAAHYENMSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVMMVRLLLDRGAQ-------IDAQTKDELT-PLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAE---------IDDI-TLDHLTPLHVAAHCGHHRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSM--DLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKNLLQRGASPNAS--NVKVETPLHMASRAGHCEVAQFLLQNAAQV-DARAKDDQTPLHCAARMGHKELVKLLLDHKANPDSATTAG--HTPLHIAAREGHIHT-IRILLDAGAQQVKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVK-LLVSKGGSAHSTARNGYTPLHIAA---KQNQIEVASVLLQNGAS--PNCESLQGITPLHLASQEGRPDMVAMLISKQANVNLGNKNGLT 668

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Medaka
Match: ankrd52a (serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C [Source:NCBI gene;Acc:101155432])

HSP 1 Score: 108.612 bits (270), Expect = 2.384e-23
Identity = 126/469 (26.87%), Postives = 203/469 (43.28%), Query Frame = 2

Query: 2486 INVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDT-------------ISTMENKNPSNSISNYESNNHYIE--GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI-----LSNNCRE--NGIVIFSLILDHYPE------FPVDEKDACGNTALFLCALKDNSRLGVALLLKGASL 3808
            + V +I    PL+ A    N + V++L     D N            E   PL  A       I D+L+E+GA V++     KD    T LHR      E+A + L+ RG +               S       + ++ ++ SN +  +  G T LH A Q G + +VK LL+    +++  +      +H A    H  V+  LL+     + S +D  G+TP H A    + +  + +L+   +  DE +  G   LH+A   M +EAV   + VN   N+   +   YTPLHLA +S      +  L+  GA++  ++ E ++ LH+A IH R      L++NG      D    TPLH+A + G+  LI  L+ N + T + + + G   LH+      S+ CR+  +   ++S++     E      F ++  D  G T L   A   N      LL  GA L
Sbjct:    1 MGVLNIADQPPLVQAIFSRNAEEVQLLLHKTEDVNALDQ--------ERRTPLHAAACVGDVHIIDLLIESGASVNV-----KDQVWLTPLHRAAASRNERAVSLLLRRGAEANARDKFWQTPLHVASANRATRCAEALLSHLSNLNIADRTGRTALHHAAQSGFQEMVKLLLNKGA-NLSAIDKKERQPIHCAAYLGHLEVVKLLLSRSN--DKSCKDKLGYTPLHAAAASGHIEIVKYLLRMGAEI-DEPNTFGNTALHMACY-MGQEAVATEL-VNHGANVNQPNKCGYTPLHLAAVSTNGALCLELLVNNGADVNQQSKEGKSPLHMAAIHGRFTRSQILIQNGGDIDCVDKYGNTPLHVAAKYGHELLISTLMTNGADTAR-RGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVSSMSKEHVLSAGFEINTPDNFGRTCLHAAASGGNVECLNLLLSSGADL 449

HSP 2 Score: 102.834 bits (255), Expect = 1.522e-21
Identity = 127/493 (25.76%), Postives = 207/493 (41.99%), Query Frame = 2

Query: 2375 KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNY------------ESNNHYIE---GNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIH------------ERVYII------SFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCA 3754
            KT +++ +  + ++ LH A   G++  +  LI+ G  +NV+    +TPL  A    N   V +L   GA+ N      +++ F +   PL VA  N     A+ L+       + +++  D   +T LH       ++    L+++G +  +  + +      + Y             SN+   +   G TPLH A   G   +VK LL     +++  N  G T+LH+A     EAV T L+N  +  N++  +  G+TP H A   +N      +L  +    ++    G++ LH+A           LIQ     +I   D +  TPLH+A   G  E LI +L+  GA+ A   I     LHLAV++             ++Y I        +L  G   +  DN   T LH A  GGNV+ +  LL +S   +  +++ G   LH  + N R    V             V+E D  G T L   A
Sbjct:   30 KTEDVNALDQERRTPLHAAACVGDVHIIDLLIESGASVNVKDQVWLTPLHRAAASRNERAVSLLLRRGAEAN------ARDKFWQ--TPLHVASANRATRCAEALLS-----HLSNLNIADRTGRTALHHAAQSGFQEMVKLLLNKGANLSAIDKKERQPIHCAAYLGHLEVVKLLLSRSNDKSCKDKLGYTPLHAAAASGHIEIVKYLLRMGA-EIDEPNTFGNTALHMACYMGQEAVATELVN--HGANVNQPNKCGYTPLHLAAVSTNGALCLELLVNNGADVNQQSKEGKSPLHMAAIHGRFTRSQILIQNGG--DIDCVDKYGNTPLHVAAKYGH-ELLISTLMTNGADTARRGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVSSMSKEHVLSAGFEINTPDNFGRTCLHAAASGGNVECLN-LLLSSGADLNKRDIMGRTPLHYAAANGRYQCTVTLV-----SAGAEVNESDQTGCTPLHYSA 497

HSP 3 Score: 88.1965 bits (217), Expect = 5.314e-17
Identity = 129/539 (23.93%), Postives = 221/539 (41.00%), Query Frame = 2

Query: 2180 TPTHLA-VKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNI----ISQEGFIELNCP-------LWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRG----------CDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAG-----ANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDE 3715
            TP HLA V T     + L +      N  +       G+SP  +   +G  +    + +          +ID +     + LH+A K G+   +  L+  G D   R I+ M PL LA      D  R L  SG   +I S++    +   GF E+N P       L  A +    +  ++L+ +GAD++      +D   +T LH      + Q    L+S G          C  +           +  + S NH  E         + G    +++LL S   D ++ N+ G +++H A    ++  L  LL   +     I      +P H A +  + +A R +L       D  D  GR+ L++A Q  +   V  L+   A+  +   +   +TP+H+A  +G   D +R +I  G      N+A++    Q  L LAV+      + FLLE  +S   QD +  T LH A   G+ D +  LL + ++ +  ++++G   LH  ++  R    ++ SL+       P D+
Sbjct:  274 TPLHLAAVSTNGALCLELLV-----NNGADVNQQSKEGKSPLHMAAIHGRFTRSQILIQ-------NGGDIDCVDKYGNTPLHVAAKYGHELLISTLMTNGADTARRGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVSSMSKEHVLSAGF-EINTPDNFGRTCLHAAASGGNVECLNLLLSSGADLNK-----RDIMGRTPLHYAAANGRYQCTVTLVSAGAEVNESDQTGCTPLHYSAASQAFGRVERHFSGNHQKEEEE------EKGSYFCLEHLLDSGA-DPSMVNSKGYSAVHYAAYHGNKQNLELLLEMSFNALGDIESSIPVSPLHLAADNGHWQALR-LLTETAAYVDMQDAAGRSVLYLAAQKGHVRCVEVLLAQGASCFLN-DNRLMWTPIHVAAANGH-SDCLRMMIDYGEEGDLTNVADKF--GQTPLMLAVLGGHTDCVRFLLERASSPDAQDKRGSTALHRAAVLGHDDCVTALLKHKASPL-CRDIQGRTPLHYAAS--RGQTEILSSLMQAAVAADPQDQ 779

HSP 4 Score: 87.0409 bits (214), Expect = 1.021e-16
Identity = 148/613 (24.14%), Postives = 253/613 (41.27%), Query Frame = 2

Query: 2183 PTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDI-VRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDT--------------------------ISTMENKNPSNSISNYESNNHYIEGNTP-------LHMACQMG-LESVVKNLLSSNKIDVNVQNATGCTSLHLAVK-FRHEAVLTHLLNPKYKLNLSIRDHQGHTPFH-TAMELSNQKAARSILQYHPQAADE--------------------IDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNK-METPLHLAVRGGNVDLIKPLLANSS----TTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            P H A    +++++ L +     ++       D  G +P      +G I    +I + L++     +EID+      + LH+A   G       L+  G ++N  +    TPL LA   +N  + + +L  +GAD N  S         E   PL +A  + RF  + IL++ G D+D       D Y  T LH       E   + L++ G DT                          +S+ +  +  +S+S     +   E NTP       LH A   G +E +  NLL S+  D+N ++  G T LH A    R++  +T L++   ++N S  D  G TP H +A   +  +  R     H +  +E                    +++ G + +H A    N++ +  L++++ N    ++ +   +PLHLA  +G  + L R L    A +  +    +++L+LA     V  +  LL  GAS    DN+ M TP+H+A   G+ D ++ ++        T +  K  +   +L +L  +      V F L     P    D +D  G+TAL   A+  +     ALL   AS  C + +G T
Sbjct:  176 PIHCAAYLGHLEVVKLLLSRSNDKS-----CKDKLGYTPLHAAAASGHI----EIVKYLLRMG---AEIDEPNTFGNTALHMACYMGQEAVATELVNHGANVNQPNKCGYTPLHLAAVSTNGALCLELLVNNGADVNQQSK--------EGKSPLHMAAIHGRFTRSQILIQNGGDIDCV-----DKYGNTPLHVAAKYGHELLISTLMTNGADTARRGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVSSMSKEHVLSAGFEINTPDNFGRTCLHAAASGGNVECL--NLLLSSGADLNKRDIMGRTPLHYAAANGRYQCTVT-LVSAGAEVNES--DQTGCTPLHYSAASQAFGRVERHFSGNHQKEEEEEKGSYFCLEHLLDSGADPSMVNSKGYSAVHYAAYHGNKQNLELLLEMSFNALGDIESSIPVSPLHLAADNGHWQAL-RLLTETAAYVDMQDAAGRSVLYLAAQKGHVRCVEVLLAQGASCFLNDNRLMWTPIHVAAANGHSDCLRMMIDYGEEGDLTNVADKFGQTPLMLAVLGGH---TDCVRFLLERASSP----DAQDKRGSTALHRAAVLGHDDCVTALLKHKASPLCRDIQGRT 750

HSP 5 Score: 78.1814 bits (191), Expect = 5.200e-14
Identity = 141/616 (22.89%), Postives = 239/616 (38.80%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIF--------------ERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANF----LISRGCDTISTMENKNPSNSI--SNYESNNHYIE----------GN-------TPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQA--ADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQD----NKMETPLHLAVRGGNVDLIKPLL---------ANSSTTIKSKNLKG-----ENIL-----HILSNNCRE-------------NGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGA 3802
            TP H+A K  +  +I+  +      N  +       G  P  L +  G    C K+               E ++   F+ +  D      ++ LH A   GN+E +  L+  G D+N R I   TPL  A           L  +GA+ N +     Q G      PL  +  +  F   +              H+  N+++        E +E+ + F    L+  G D   +M N    +++  + Y  N   +E          G+       +PLH+A   G    ++ LL+     V++Q+A G + L+LA +  H   +  LL       L+  +    TP H A    +    R ++ Y  +    +  D  G+  L +AV   + + V FL++  ++ +   +D    T LH A + G  +D + +L+   A+     I+ +  LH A    +  I+S L++   +   QD    NK  TPLH A   G+ D ++ LL          N  T +    + G     E +L     H++  NCR+               +    L+L H  E  ++  D  G +AL + A K +S   VA+LL  A
Sbjct:  341 TPLHVAAKYGHELLISTLM-----TNGADTARRGIHGMFPLHLAVLYGFSDCCRKLLSSGQLYSIVSSMSKEHVLSAGFEINTPDNF---GRTCLHAAASGGNVECLNLLLSSGADLNKRDIMGRTPLHYAAANGRYQCTVTLVSAGAEVNESD----QTGCT----PLHYSAASQAFGRVER-------------HFSGNHQKE-------EEEEKGSYFCLEHLLDSGAD--PSMVNSKGYSAVHYAAYHGNKQNLELLLEMSFNALGDIESSIPVSPLHLAADNGHWQALR-LLTETAAYVDMQDAAGRSVLYLAAQKGHVRCVEVLLAQGASCFLN-DNRLMWTPIHVAAANGHSDCLRMMIDYGEEGDLTNVADKFGQTPLMLAVLGGHTDCVRFLLERASSPD--AQDKRGSTALHRAAVLGH-DDCVTALLKHKASPLCRDIQGRTPLHYAASRGQTEILSSLMQAAVAADPQDQLLDNKQYTPLHWAAYKGHEDCLEVLLELKTFIHEEGNPFTPLHCALMNGHCSAAERLLESARVHVI--NCRDAKGRSPLHAAAFAEDVAGLQLVLRHGAE--INAVDNSGRSALMVAADKGHSGT-VAILLHRA 908

HSP 6 Score: 73.559 bits (179), Expect = 1.491e-12
Identity = 102/430 (23.72%), Postives = 172/430 (40.00%), Query Frame = 2

Query: 2414 SLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHY-----------------IEGNTPLHMACQMG----LESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLL----------NPKYKLNLSI----------------------RDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGA-------NIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETP 3523
            S LHLA   G+ +A++ L +    ++++     + L LA +K ++  V +L   GA   +  N +       +  P+ VA  N   D   ++++ G + D+ ++   D + QT L   +L        FL+ R   +    ++K  S ++       H                  I+G TPLH A   G    L S+++  ++++  D  + N    T LH A    HE  L  LL          NP   L+ ++                      RD +G +P H A   +   A   ++  H    + +DN GR+ L VA    +   V  L+   A  ++ + D  + T LHLA  S A E  + +L++ G        N  N  +  Q  LHLA  +    ++  LL  GA+    D +  TP
Sbjct:  581 SPLHLAADNGHWQALRLLTETAAYVDMQDAAGRSVLYLAAQKGHVRCVEVLLAQGASCFLNDNRL-------MWTPIHVAAANGHSDCLRMMIDYGEEGDLTNV--ADKFGQTPLMLAVLGGHTDCVRFLLERA--SSPDAQDKRGSTALHRAAVLGHDDCVTALLKHKASPLCRDIQGRTPLHYAASRGQTEILSSLMQAAVAADPQDQLLDNKQ-YTPLHWAAYKGHEDCLEVLLELKTFIHEEGNPFTPLHCALMNGHCSAAERLLESARVHVINCRDAKGRSPLHAAA-FAEDVAGLQLVLRHGAEINAVDNSGRSALMVAADKGHSGTVAILLH-RAKADLTLLDENKNTALHLAC-SKAHE--MCALLILGEIHSPTLINATNSAL--QMPLHLAARNGLATVVQALLSRGATVLAVDEEGHTP 991

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BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Planmine SMEST
Match: SMESG000033451.1 (SMESG000033451.1)

HSP 1 Score: 2509.18 bits (6502), Expect = 0.000e+0
Identity = 1308/1351 (96.82%), Postives = 1308/1351 (96.82%), Query Frame = 2

Query:   53 MTDETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVDNYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEAXXXXXXXXXXXXXXGAXXXXXXXXXXXXXKPL*INMAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYXXXXXXXXXXXLKKDSELTNHVNNEIYEQTQNXXXXXXXXXXXXXXXXMNPFKEYMKIENDDYHSLSLSLPMIRKSNANRGLLMDLALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNGKFQ 4105
            MTDETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCEEINLENEEQNIGEQIVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLA   K                       SLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEALTTINTITNLLIQNGADVNNVDNNDM                 TALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYSSCDSMHSYSSLKKDSELTNHVNNEIYEQTQNDSSDSVISSWSSKTDDMNPFKEYMKIENDDYHSLSLSLPMIRKSNANRGLLMDLALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNGKFQ
Sbjct:    1 MTDETLLKHFNLLQQEYHKINNKYQSLKTKYDNLILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCEEINLENEEQNIGEQIVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFCSNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFLYINENYSQLEELVNVISEDNELVLDLAFRVK-----------------------SLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPSHEDAEALTTINTITNLLIQNGADVNNVDNNDM-----------------TALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKSNSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFMLIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNNQGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVRRRPITANNSNSKDDIYSSCDSMHSYSSLKKDSELTNHVNNEIYEQTQNDSSDSVISSWSSKTDDMNPFKEYMKIENDDYHSLSLSLPMIRKSNANRGLLMDLALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFILKLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEMPIIKFNIKKPVRVCEVCFNFLVNGKFQ 1311

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Planmine SMEST
Match: SMESG000066578.1 (SMESG000066578.1)

HSP 1 Score: 141.739 bits (356), Expect = 3.424e-38
Identity = 85/97 (87.63%), Postives = 87/97 (89.69%), Query Frame = 2

Query:  212 IVRSLYKDKKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNR 502
            I   +  DKK SDISIKLQKSTI GHRIIFEANGCEWNGSDLSNCEEINL NEEQNIG+QIVKWIYLQELND QNY ILWKLMKVAHEHNLKYLKNR
Sbjct:    6 ICSLIISDKKVSDISIKLQKSTIQGHRIIFEANGCEWNGSDLSNCEEINLVNEEQNIGKQIVKWIYLQELNDTQNYGILWKLMKVAHEHNLKYLKNR 102

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Planmine SMEST
Match: SMESG000066578.1 (SMESG000066578.1)

HSP 1 Score: 138.272 bits (347), Expect = 6.761e-37
Identity = 82/89 (92.13%), Postives = 84/89 (94.38%), Query Frame = 2

Query:  236 KKFSDISIKLQKSTIPGHRIIFEANGCEWNGSDLSNCXXXXXXXXXXXXXXXXVKWIYLQELNDNQNYEILWKLMKVAHEHNLKYLKNR 502
            K+ SDISIKLQKSTI GHRIIFEANGCEWNGSDLSNCEEINL NEEQNIG+QIVKWIYLQELND QNY ILWKLMKVAHEHNLKYLKNR
Sbjct:   20 KEVSDISIKLQKSTIQGHRIIFEANGCEWNGSDLSNCEEINLVNEEQNIGKQIVKWIYLQELNDTQNYGILWKLMKVAHEHNLKYLKNR 108

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1)

HSP 1 Score: 126.716 bits (317), Expect = 9.715e-29
Identity = 144/564 (25.53%), Postives = 237/564 (42.02%), Query Frame = 2

Query: 2345 IFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE----------------------------AGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDT-ISTMENKNPSNSISNYESNN--------------HYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT-LFNSEHISEQFILKLLDSLSSEP 3904
            I + LIK   +   ID       S LH+A   G  E V+ L++ G ++N++S N  TPL +A +++++++V  L  +GAD  IT    +++GF     PL VAL      I  +L+E                              ++VD   ++++ +   T LH       E++A  LI +  D       N  P +  + +  +                  +G TPLH + + G   + + L+  N  DV  +   G TSLH+A +   E     LL  +  +N +  D    TP H      N+K AR +L           N G   LH+A +    + V  L++  A +    +     TPLH++   G+ E  +  L+  GANI   T+  +  LHLA  + +   +  LL+ GA    +  + +TPLH+A + GN++LI  L   S +            LH+ +   R   I   SL+LD   +   + K   G T L + A  D   +   LL K A+       G T L  + H + + + +LL    ++P
Sbjct:   59 IVKELIK---REPRIDATTKKGNSALHIASLAGKFEVVKILVENGANVNLQSTNGFTPLYMAAQENHLEVVTFLINNGADQTIT----TEDGF----TPLAVALQQGHERIVALLLENDNRSKQRLPALHIAVKKNDVNAVNLLLNSSEVD---VNHQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDSGALVSCRTRDGLTPLHCSARSGHAQLCEKLI-DNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFL--TPLHVTAHYGNEKVARVLLDRRCDPNARALN-GFTPLHIACKKHKIKIVELLLKYGALIEATTETGL--TPLHVSAFIGSKE-AVNMLLQKGANIEQGTMRGETALHLATRNNQTETVKLLLKAGAIPDAKARENQTPLHVATKIGNLELIT-LFLQSGSDPNVATRDNYTALHVAAKEGRSEAI---SLLLDSGAKIEAETKR--GFTPLHIAAKYDKVGVASILLQKKANPNATGKNGLTPLHVATHYNHEKVAQLLLDNKADP 595

HSP 2 Score: 120.168 bits (300), Expect = 8.968e-27
Identity = 146/570 (25.61%), Postives = 242/570 (42.46%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIG-CDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITS--NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPS---NSISNYES------------NNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            TP ++A +  +++++   I      N  +  +    G +P  + L  G     ++I   L++ D ++ +           LH+AVKK ++ AV  L+     D+N +S +  TPL +A    N    ++L    AD N  +  NI           PL VA    R  +  +L+++GA   + S   +D    T LH +      Q    LI  G D +S   N   S    +  ++E             N    +  TPLH+    G E V + LL   + D N +   G T LH+A K +H+  +  LL  KY   +      G TP H +  + +++A   +LQ      ++    G   LH+A +    E V  L++  A  + + ++    TPLH+A   G  E LI   + +G++    T +    LH+A    R   IS LL++GA    +  +  TPLH+A +   V +   LL   +    + N  G+N L  L      N   +  L+LD+  +     K+  G T L + A K+N  L + LL+  A     +  GF+
Sbjct:  112 TPLYMAAQENHLEVVTFLI-----NNGADQTITTEDGFTPLAVALQQG----HERIVALLLENDNRSKQ-------RLPALHIAVKKNDVNAVNLLLNSSEVDVNHQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNI----------TPLHVAAKWGRSGMVQLLIDSGA---LVSCRTRDGL--TPLHCSARSGHAQLCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLLD-RRCDPNARALNGFTPLHIACK-KHKIKIVELL-LKYGALIEATTETGLTPLHVSAFIGSKEAVNMLLQKGANI-EQGTMRGETALHLATRNNQTETVKLLLKAGAIPDAKARE--NQTPLHVATKIGNLE-LITLFLQSGSDPNVATRDNYTALHVAAKEGRSEAISLLLDSGAKIEAETKRGFTPLHIAAKYDKVGVASILLQKKA----NPNATGKNGLTPLHVATHYNHEKVAQLLLDNKADPKCKAKN--GYTPLHIAAKKNNQDLAIMLLVSDADSNAESRNGFS 637

HSP 3 Score: 110.923 bits (276), Expect = 5.565e-24
Identity = 127/494 (25.71%), Postives = 203/494 (41.09%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLM--NDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLI---RSLILAGANIANETIEKQNLLHLAV----IHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI 3634
            TP H+A K   IKI+ L +       K   L+      G +P  +  + G     + + +       K + I++  +  ++ LHLA +    E V+ L+K G   + ++    TPL +AT+  N++++ +   SG+DPN+ +                                            +DNY  T LH    E + +A + L+  G    +  +                   G TPLH+A +     V   LL   K + N     G T LH+A  + HE V   LL+   K +   +   G+TP H A + +NQ  A  +L     +  E  N G + L +A Q  + + V  L+Q  A++N + K+    T +HL     A ED +   R L+ AGA+I   T  +   LH A     I+   Y+IS + +N  +   Q     TPLHLA + G++ L+  LL  S      KN +G    HI
Sbjct:  373 TPLHIACKKHKIKIVELLL-------KYGALIEATTETGLTPLHVSAFIGSKEAVNMLLQ-------KGANIEQGTMRGETALHLATRNNQTETVKLLLKAGAIPDAKARENQTPLHVATKIGNLELITLFLQSGSDPNVAT--------------------------------------------RDNY--TALHVAAKEGRSEAISLLLDSGAKIEAETK------------------RGFTPLHIAAKYDKVGVASILL-QKKANPNATGKNGLTPLHVATHYNHEKVAQLLLD--NKADPKCKAKNGYTPLHIAAKKNNQDLAIMLLVSDADSNAESRN-GFSPLQLASQEGHTDVVSLLLQHKADVNHKAKNGL--TSMHLT----AQEDKVTVARILVHAGADITPTTTAEYTPLHTAAHFGQINMAKYLISLMDQNQINQKTQLGF--TPLHLAAQQGHLQLVN-LLLESRADPNIKNNQGWTAAHI 775

HSP 4 Score: 100.523 bits (249), Expect = 8.488e-21
Identity = 136/593 (22.93%), Postives = 240/593 (40.47%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFER----LIKT-------------DF---------KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC-DTISTMENKNP---SNSISNYESNNHYIE-GNTP----------LHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            TP H+A K     ++ L I  D G   V+    D  G +P      +G   +C+K+ +     + KT             DF         K + I++   D  + LH+    GN +  + L+   CD N R++N  TPL +A +K  I IV +L   GA    T+    + G   L+   ++       +  ++L++ GA+++  ++       +T LH      + +    L+  G        EN+ P   +  I N E    +++ G+ P          LH+A + G    +  LL S    +  +   G T LH+A K+    V + LL  K   N + ++  G TP H A   +++K A+ +L        +  N G   LH+A +  N++    L+  +A+ N   ++ F  +PL LA   G   D++  L+   A++ ++       +HL    ++V +   L+  GA  +       TPLH A   G +++ K L++                  ++  N                    +++K   G T L L A + + +L   LL   A     NN+G+T
Sbjct:  241 TPLHVAAKWGRSGMVQLLI--DSGA-LVSCRTRD--GLTPLHCSARSGHAQLCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLLDRRCDPNARALNGFTPLHIACKKHKIKIVELLLKYGALIEATT----ETGLTPLHVSAFIGSK----EAVNMLLQKGANIEQGTMRG-----ETALHLATRNNQTETVKLLLKAGAIPDAKARENQTPLHVATKIGNLELITLFLQSGSDPNVATRDNYTALHVAAKEGRSEAISLLLDSGA-KIEAETKRGFTPLHIAAKYDKVGVASILLQKKANPNATGKN--GLTPLHVATHYNHEKVAQLLLDNKADPKCKAKN-GYTPLHIAAKKNNQDLAIMLLVSDADSNAESRNGF--SPLQLASQEGH-TDVVSLLLQHKADVNHKAKNGLTSMHLTAQEDKVTVARILVHAGADITPTTTAEYTPLHTAAHFGQINMAKYLIS------------------LMDQN-------------------QINQKTQLGFTPLHLAAQQGHLQLVNLLLESRADPNIKNNQGWT 771

HSP 5 Score: 99.3673 bits (246), Expect = 1.639e-20
Identity = 127/463 (27.43%), Postives = 209/463 (45.14%), Query Frame = 2

Query: 2429 AVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRN---FLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASL 3808
            A + GN+  V   ++ G DIN  +   ++ L LA ++ +I IV+ L     +P I  +  +++G    N  L +A    +F++  ILVE GA+V++ S +       T L+    E   +   FLI+ G D   T E                  +G TPL +A Q G E +V  LL ++      ++     +LH+AVK      +  LLN   +++++ +   G TP H A    N+K+A+ +++   Q AD ++   +N    LHVA +      V  LI   A ++ R +D    TPLH +  SG  + L   LI  GA++ ++T      LH+A   +       LL   A+ +       TPLH+    GN  + + LL +      ++ L G   LHI    C+++ I I  L+L  Y    ++     G T L + A   +      LL KGA++
Sbjct:   18 AARAGNLSKVIDFLETGTDINTCNDIGLSALHLAAKEGHIVIVKELI--KREPRI--DATTKKG----NSALHIASLAGKFEVVKILVENGANVNLQSTNGF-----TPLYMAAQENHLEVVTFLINNGADQTITTE------------------DGFTPLAVALQQGHERIVALLLENDN-----RSKQRLPALHIAVKKNDVNAVNLLLN-SSEVDVNHQSSSGFTPLHIAAHYGNEKSAQLLIE---QKAD-VNFQAKNNITPLHVAAKWGRSGMVQLLIDSGALVSCRTRDGL--TPLHCSARSGHAQ-LCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLL-DRRCDPNARALNGFTPLHIA---CKKHKIKIVELLL-KYGAL-IEATTETGLTPLHVSAFIGSKEAVNMLLQKGANI 430

HSP 6 Score: 62.003 bits (149), Expect = 4.665e-9
Identity = 67/229 (29.26%), Postives = 108/229 (47.16%), Query Frame = 2

Query: 2873 ESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNL--LHLAVIHERVYIISFLLENG-ASTSHQDNKMETPLHLAVRGGN 3550
            +SN    E N     A + G  S V + L +   D+N  N  G ++LHLA K  H  ++  L+  + +++ + +  +G++  H A  L+ +     IL  +    +     G   L++A Q  + E V FLI   A+  I  +D F  TPL +A+  G   + I +L+L      N+   KQ L  LH+AV    V  ++ LL +     +HQ +   TPLH+A   GN
Sbjct:    3 KSNTENSESNHSFLRAARAGNLSKVIDFLETG-TDINTCNDIGLSALHLAAKEGHIVIVKELIKREPRIDATTK--KGNSALHIA-SLAGKFEVVKILVENGANVNLQSTNGFTPLYMAAQENHLEVVTFLINNGADQTITTEDGF--TPLAVALQQG--HERIVALLL-----ENDNRSKQRLPALHIAVKKNDVNAVNLLLNSSEVDVNHQSSSGFTPLHIAAHYGN 218

[Close]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1)

HSP 1 Score: 126.331 bits (316), Expect = 1.037e-28
Identity = 144/564 (25.53%), Postives = 237/564 (42.02%), Query Frame = 2

Query: 2345 IFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVE----------------------------AGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDT-ISTMENKNPSNSISNYESNN--------------HYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT-LFNSEHISEQFILKLLDSLSSEP 3904
            I + LIK   +   ID       S LH+A   G  E V+ L++ G ++N++S N  TPL +A +++++++V  L  +GAD  IT    +++GF     PL VAL      I  +L+E                              ++VD   ++++ +   T LH       E++A  LI +  D       N  P +  + +  +                  +G TPLH + + G   + + L+  N  DV  +   G TSLH+A +   E     LL  +  +N +  D    TP H      N+K AR +L           N G   LH+A +    + V  L++  A +    +     TPLH++   G+ E  +  L+  GANI   T+  +  LHLA  + +   +  LL+ GA    +  + +TPLH+A + GN++LI  L   S +            LH+ +   R   I   SL+LD   +   + K   G T L + A  D   +   LL K A+       G T L  + H + + + +LL    ++P
Sbjct:   59 IVKELIK---REPRIDATTKKGNSALHIASLAGKFEVVKILVENGANVNLQSTNGFTPLYMAAQENHLEVVTFLINNGADQTIT----TEDGF----TPLAVALQQGHERIVALLLENDNRSKQRLPALHIAVKKNDVNAVNLLLNSSEVD---VNHQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDSGALVSCRTRDGLTPLHCSARSGHAQLCEKLI-DNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFL--TPLHVTAHYGNEKVARVLLDRRCDPNARALN-GFTPLHIACKKHKIKIVELLLKYGALIEATTETGL--TPLHVSAFIGSKE-AVNMLLQKGANIEQGTMRGETALHLATRNNQTETVKLLLKAGAIPDAKARENQTPLHVATKIGNLELIT-LFLQSGSDPNVATRDNYTALHVAAKEGRSEAI---SLLLDSGAKIEAETKR--GFTPLHIAAKYDKVGVASILLQKKANPNATGKNGLTPLHVATHYNHEKVAQLLLDNKADP 595

HSP 2 Score: 120.168 bits (300), Expect = 8.952e-27
Identity = 146/570 (25.61%), Postives = 242/570 (42.46%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIG-CDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITS--NIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPS---NSISNYES------------NNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            TP ++A +  +++++   I      N  +  +    G +P  + L  G     ++I   L++ D ++ +           LH+AVKK ++ AV  L+     D+N +S +  TPL +A    N    ++L    AD N  +  NI           PL VA    R  +  +L+++GA   + S   +D    T LH +      Q    LI  G D +S   N   S    +  ++E             N    +  TPLH+    G E V + LL   + D N +   G T LH+A K +H+  +  LL  KY   +      G TP H +  + +++A   +LQ      ++    G   LH+A +    E V  L++  A  + + ++    TPLH+A   G  E LI   + +G++    T +    LH+A    R   IS LL++GA    +  +  TPLH+A +   V +   LL   +    + N  G+N L  L      N   +  L+LD+  +     K+  G T L + A K+N  L + LL+  A     +  GF+
Sbjct:  112 TPLYMAAQENHLEVVTFLI-----NNGADQTITTEDGFTPLAVALQQG----HERIVALLLENDNRSKQ-------RLPALHIAVKKNDVNAVNLLLNSSEVDVNHQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNI----------TPLHVAAKWGRSGMVQLLIDSGA---LVSCRTRDGL--TPLHCSARSGHAQLCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLLD-RRCDPNARALNGFTPLHIACK-KHKIKIVELL-LKYGALIEATTETGLTPLHVSAFIGSKEAVNMLLQKGANI-EQGTMRGETALHLATRNNQTETVKLLLKAGAIPDAKARE--NQTPLHVATKIGNLE-LITLFLQSGSDPNVATRDNYTALHVAAKEGRSEAISLLLDSGAKIEAETKRGFTPLHIAAKYDKVGVASILLQKKA----NPNATGKNGLTPLHVATHYNHEKVAQLLLDNKADPKCKAKN--GYTPLHIAAKKNNQDLAIMLLVSDADSNAESRNGFS 637

HSP 3 Score: 110.923 bits (276), Expect = 5.650e-24
Identity = 127/494 (25.71%), Postives = 203/494 (41.09%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLM--NDYAGESPFTLCLWNGLISVCDKIFERLIKTDFKTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLI---RSLILAGANIANETIEKQNLLHLAV----IHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHI 3634
            TP H+A K   IKI+ L +       K   L+      G +P  +  + G     + + +       K + I++  +  ++ LHLA +    E V+ L+K G   + ++    TPL +AT+  N++++ +   SG+DPN+ +                                            +DNY  T LH    E + +A + L+  G    +  +                   G TPLH+A +     V   LL   K + N     G T LH+A  + HE V   LL+   K +   +   G+TP H A + +NQ  A  +L     +  E  N G + L +A Q  + + V  L+Q  A++N + K+    T +HL     A ED +   R L+ AGA+I   T  +   LH A     I+   Y+IS + +N  +   Q     TPLHLA + G++ L+  LL  S      KN +G    HI
Sbjct:  373 TPLHIACKKHKIKIVELLL-------KYGALIEATTETGLTPLHVSAFIGSKEAVNMLLQ-------KGANIEQGTMRGETALHLATRNNQTETVKLLLKAGAIPDAKARENQTPLHVATKIGNLELITLFLQSGSDPNVAT--------------------------------------------RDNY--TALHVAAKEGRSEAISLLLDSGAKIEAETK------------------RGFTPLHIAAKYDKVGVASILL-QKKANPNATGKNGLTPLHVATHYNHEKVAQLLLD--NKADPKCKAKNGYTPLHIAAKKNNQDLAIMLLVSDADSNAESRN-GFSPLQLASQEGHTDVVSLLLQHKADVNHKAKNGL--TSMHLT----AQEDKVTVARILVHAGADITPTTTAEYTPLHTAAHFGQINMAKYLISLMDQNQINQKTQLGF--TPLHLAAQQGHLQLVN-LLLESRADPNIKNNQGWTAAHI 775

HSP 4 Score: 100.523 bits (249), Expect = 8.126e-21
Identity = 136/597 (22.78%), Postives = 238/597 (39.87%), Query Frame = 2

Query: 2180 TPTHLAVKTKNIKIINLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFER----LIKT-------------DF---------KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGC-DTISTMENKNP------------------SNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFT 3835
            TP H+A K     ++ L I  D G   V+    D  G +P      +G   +C+K+ +     + KT             DF         K + I++   D  + LH+    GN +  + L+   CD N R++N  TPL +A +K  I IV +L   GA    T+    + G   L+   ++       +  ++L++ GA+++  ++       +T LH      + +    L+  G        EN+ P                  S S  N  + ++Y    T LH+A + G    +  LL S    +  +   G T LH+A K+    V + LL  K   N + ++  G TP H A   +++K A+ +L        +  N G   LH+A +  N++    L+  +A+ N   ++ F  +PL LA   G   D++  L+   A++ ++       +HL    ++V +   L+  GA  +       TPLH A   G +++ K L++                  ++  N                    +++K   G T L L A + + +L   LL   A     NN+G+T
Sbjct:  241 TPLHVAAKWGRSGMVQLLI--DSGA-LVSCRTRD--GLTPLHCSARSGHAQLCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLLDRRCDPNARALNGFTPLHIACKKHKIKIVELLLKYGALIEATT----ETGLTPLHVSAFIGSK----EAVNMLLQKGANIEQGTMRG-----ETALHLATRNNQTETVKLLLKAGAIPDAKARENQTPLHVATKIGNLELITLFLQSGSDPNVATRDNY----TALHVAAKEGRSEAISLLLDSGA-KIEAETKRGFTPLHIAAKYDKVGVASILLQKKANPNATGKN--GLTPLHVATHYNHEKVAQLLLDNKADPKCKAKN-GYTPLHIAAKKNNQDLAIMLLVSDADSNAESRNGF--SPLQLASQEGH-TDVVSLLLQHKADVNHKAKNGLTSMHLTAQEDKVTVARILVHAGADITPTTTAEYTPLHTAAHFGQINMAKYLIS------------------LMDQN-------------------QINQKTQLGFTPLHLAAQQGHLQLVNLLLESRADPNIKNNQGWT 771

HSP 5 Score: 99.7525 bits (247), Expect = 1.569e-20
Identity = 127/463 (27.43%), Postives = 209/463 (45.14%), Query Frame = 2

Query: 2429 AVKKGNIEAVQFLIKIGCDINVRSINKMTPLLLATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFDIADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDTISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRN---FLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNLLHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLLANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDACGNTALFLCALKDNSRLGVALLLKGASL 3808
            A + GN+  V   ++ G DIN  +   ++ L LA ++ +I IV+ L     +P I  +  +++G    N  L +A    +F++  ILVE GA+V++ S +       T L+    E   +   FLI+ G D   T E                  +G TPL +A Q G E +V  LL ++      ++     +LH+AVK      +  LLN   +++++ +   G TP H A    N+K+A+ +++   Q AD ++   +N    LHVA +      V  LI   A ++ R +D    TPLH +  SG  + L   LI  GA++ ++T      LH+A   +       LL   A+ +       TPLH+    GN  + + LL +      ++ L G   LHI    C+++ I I  L+L  Y    ++     G T L + A   +      LL KGA++
Sbjct:   18 AARAGNLSKVIDFLETGTDINTCNDIGLSALHLAAKEGHIVIVKELI--KREPRI--DATTKKG----NSALHIASLAGKFEVVKILVENGANVNLQSTNGF-----TPLYMAAQENHLEVVTFLINNGADQTITTE------------------DGFTPLAVALQQGHERIVALLLENDN-----RSKQRLPALHIAVKKNDVNAVNLLLN-SSEVDVNHQSSSGFTPLHIAAHYGNEKSAQLLIE---QKAD-VNFQAKNNITPLHVAAKWGRSGMVQLLIDSGALVSCRTRDGL--TPLHCSARSGHAQ-LCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLL-DRRCDPNARALNGFTPLHIA---CKKHKIKIVELLL-KYGAL-IEATTETGLTPLHVSAFIGSKEAVNMLLQKGANI 430

HSP 6 Score: 62.003 bits (149), Expect = 4.357e-9
Identity = 67/229 (29.26%), Postives = 108/229 (47.16%), Query Frame = 2

Query: 2873 ESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKIDVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHTAMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQVNANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNL--LHLAVIHERVYIISFLLENG-ASTSHQDNKMETPLHLAVRGGN 3550
            +SN    E N     A + G  S V + L +   D+N  N  G ++LHLA K  H  ++  L+  + +++ + +  +G++  H A  L+ +     IL  +    +     G   L++A Q  + E V FLI   A+  I  +D F  TPL +A+  G   + I +L+L      N+   KQ L  LH+AV    V  ++ LL +     +HQ +   TPLH+A   GN
Sbjct:    3 KSNTENSESNHSFLRAARAGNLSKVIDFLETG-TDINTCNDIGLSALHLAAKEGHIVIVKELIKREPRIDATTK--KGNSALHIA-SLAGKFEVVKILVENGANVNLQSTNGFTPLYMAAQENHLEVVTFLINNGADQTITTEDGF--TPLAVALQQG--HERIVALLL-----ENDNRSKQRLPALHIAVKKNDVNAVNLLLNSSEVDVNHQSSSGFTPLHIAAHYGN 218

The following BLAST results are available for this feature:

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Human
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Celegans
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Fly
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Zebrafish
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Xenopus
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Mouse
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. UniProt/SwissProt
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. TrEMBL
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Cavefish
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Sea Lamprey
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Yeast
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Nematostella
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Medaka
BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Planmine SMEST

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANKFY1	1.893e-132	38.80	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ANKFY1	1.893e-132	38.80	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ANKFY1	5.617e-132	38.80	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ANKFY1	8.495e-131	38.74	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ANK2	2.927e-31	27.26	ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
F22G12.4	5.565e-60	30.18	pep chromosome:WBcel235:I:13155239:13159179:-1 gen...	[more]
F22G12.4	1.592e-59	30.18	pep chromosome:WBcel235:I:13155239:13159874:-1 gen...	[more]
F22G12.4	5.537e-59	30.18	pep chromosome:WBcel235:I:13155239:13161508:-1 gen...	[more]
unc-44	1.290e-27	25.77	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	1.290e-27	25.77	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG41099	2.694e-99	34.36	gene:FBgn0039955 transcript:FBtr0113991	[more]
CG41099	2.694e-99	34.36	gene:FBgn0039955 transcript:FBtr0344573	[more]
CG41099	3.101e-99	34.36	gene:FBgn0039955 transcript:FBtr0113989	[more]
CG41099	3.802e-99	34.36	gene:FBgn0039955 transcript:FBtr0113990	[more]
Ank2	2.458e-34	27.17	gene:FBgn0261788 transcript:FBtr0344224	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ankfy1	1.596e-133	38.49	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ankfy1	2.440e-133	38.49	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ankfy1	1.481e-130	38.33	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ankfy1	1.481e-130	38.33	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ank2b	6.777e-30	25.97	ankyrin 2b, neuronal [Source:ZFIN;Acc:ZDB-GENE-041...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cilp	6.573e-139	39.69	cartilage intermediate layer protein [Source:Xenba...	[more]
cilp	2.997e-138	39.69	cartilage intermediate layer protein [Source:Xenba...	[more]
cilp	3.028e-138	39.69	cartilage intermediate layer protein [Source:Xenba...	[more]
cilp	5.745e-138	39.69	cartilage intermediate layer protein [Source:Xenba...	[more]
ANK2	1.093e-31	26.85	ankyrin 2, neuronal [Source:NCBI gene;Acc:10049480...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ankfy1	8.493e-134	39.26	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
Ankfy1	8.677e-60	35.14	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
Ank2	1.425e-32	28.03	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]
Ank2	1.588e-32	28.03	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]
Ank2	2.342e-32	27.63	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q810B6\|ANFY1_MOUSE	5.940e-133	39.26	Rabankyrin-5 OS=Mus musculus OX=10090 GN=Ankfy1 PE...	[more]
sp\|Q9P2R3\|ANFY1_HUMAN	9.093e-132	38.80	Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=...	[more]
sp\|Q8C8R3\|ANK2_MOUSE	7.794e-32	28.03	Ankyrin-2 OS=Mus musculus OX=10090 GN=Ank2 PE=1 SV...	[more]
sp\|Q01484\|ANK2_HUMAN	1.060e-30	27.49	Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=...	[more]
sp\|O70511\|ANK3_RAT	5.210e-27	26.08	Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3Q0KLX9	5.240e-164	30.51	Ankyrin repeat and fyve domain containing,putative...	[more]
A0A4S2LAB3	1.013e-158	30.14	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A1L8H8C4	9.898e-139	39.31	Uncharacterized protein OS=Xenopus laevis OX=8355 ...	[more]
A0A1S3HUN5	1.176e-138	40.28	rabankyrin-5 OS=Lingula unguis OX=7574 GN=LOC10615...	[more]
A0A1L8HGA0	3.647e-138	39.91	Uncharacterized protein OS=Xenopus laevis OX=8355 ...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ankfy1	6.721e-138	39.06	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ankfy1	3.393e-114	37.14	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ankfy1	4.566e-114	37.14	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ENSAMXT00000017800.2	7.307e-32	26.34	pep primary_assembly:Astyanax_mexicanus-2.0:16:210...	[more]
ank3a	4.193e-29	25.38	ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ankfy1	3.282e-135	39.88	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ENSPMAT00000000095.1	5.642e-32	26.37	pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 g...	[more]
ENSPMAT00000000093.1	1.836e-31	25.86	pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 g...	[more]
ENSPMAT00000007446.1	1.257e-23	23.99	pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1...	[more]
ENSPMAT00000007449.1	7.092e-23	27.65	pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
VPS27	6.632e-14	36.84	Endosomal protein that forms a complex with Hse1p;...	[more]
NAS6	3.508e-12	33.33	Evolutionarily conserved 19S regulatory particle a...	[more]
HOS4	2.900e-7	41.94	Subunit of the Set3 complex; complex is a meiotic-...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39873	7.807e-48	32.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39875	1.133e-47	47.27	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44864	1.933e-13	46.88	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48232	6.575e-11	40.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38501	5.808e-10	44.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ankfy1	2.733e-135	39.38	ankyrin repeat and FYVE domain containing 1 [Sourc...	[more]
ENSORLT00000031565.1	1.858e-31	26.48	ankyrin 2 [Source:NCBI gene;Acc:101161458]	[more]
ENSORLT00000039458.1	2.268e-31	26.48	ankyrin 2 [Source:NCBI gene;Acc:101161458]	[more]
ank1b	1.856e-25	24.86	ankyrin-1 [Source:NCBI gene;Acc:101157380]	[more]
ankrd52a	2.384e-23	26.87	serine/threonine-protein phosphatase 6 regulatory ...	[more]

BLAST of Ankyrin repeat and FYVE domain containing 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000033451.1	0.000e+0	96.82	SMESG000033451.1	[more]
SMESG000066578.1	3.424e-38	87.63	SMESG000066578.1	[more]
SMESG000066578.1	6.761e-37	92.13	SMESG000066578.1	[more]
SMESG000000606.1	9.715e-29	25.53	SMESG000000606.1	[more]
SMESG000000606.1	1.037e-28	25.53	SMESG000000606.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30030576 ID=SMED30030576|Name=Ankyrin repeat and FYVE domain containing 1|organism=Schmidtea mediterranea sexual|type=transcript|length=4215bp
ATCTCGAAATTTGAATGTTAAATTTAAAATAAATTTATTAAATAATCAAA
TAATGACCGATGAAACTTTATTGAAACATTTTAATTTATTGCAACAAGAA
TATCATAAAATTAATAATAAATACCAATCATTGAAAACGAAGTACGACAA
TCTTATATTATTATCAGGAAATCCATCAACAGAAGACAATTTTTGGATTA
ATCTTAATAAAATAGTCCGAAGTCTTTATAAAGATAAAAAGTTCAGTGAT
ATTTCTATTAAACTTCAAAAAAGCACTATTCCAGGTCATCGAATTATTTT
TGAAGCAAACGGCTGTGAGTGGAATGGATCAGATCTAAGTAATTGTGAAG
AAATTAATTTAGAAAATGAAGAACAAAATATCGGCGAACAAATTGTCAAA
TGGATTTACTTACAAGAATTAAATGATAATCAAAATTATGAAATTTTATG
GAAATTAATGAAAGTTGCCCATGAGCATAATTTAAAATATCTAAAAAATC
GTTGTGAATCAGGATTTATCTCCAAAGTTTCAAAAGATAATTGCATTTAC
TTTTATAAGAAAGCATCTGAATTCTCTGTTGAAAATTTAAGAAGTTTTTG
TTCAAACCTGATTATTGCTAATTGGAATGAGTACCAACCTGCGGATTTCG
ATGGTTTGGAAGCCAGCATATTTCTTGATTTATTAGAAGCCCAATCAAAT
TATCCATTACATGAAGCTGTAAAAGCTAATCGAGATGATGTCGTTTTTTT
GTACATAAATGAAAATTATTCGCAGCTCGAAGAGCTAGTCAACGTTATCA
GTGAAGACAATGAACTTGTATTGGATTTAGCTCTTTCGAGTAAAAAGGTG
GAGCTATGTGAAACGCTTTTGAAAAGCTGTGCAAATTTGAATTCTGTTGA
TAATTACGGTTGGAGTCTGTTGCACAAAGCCATTCAAAGACAAGATGAAT
TTTCGTGTAGATTTCTAATTCAAAATGGCTGTCATCTAAATCCATTAAGC
CCAGATTTATCGCAAACTCCCATTCAATTACTTGCTAATTTAATACCTTC
TCATGAGGATGCAGAAGCTTTGACAACAATTAATACAATTACCAATCTTT
TGATTCAAAATGGGGCCGATGTGAATAATGTTGATAATAATGACATGTGA
GTAGTAAAACCATTGTAAATTAACATGGCATGGAATTATTTTTTTAGGAC
AGCTCTATGTCTTGCTATATTATCTGGTAATGAAATAGTAATGAAAGCAG
TTTTAGATAGTGGGCGTTGTAATTCAATTAACGGAGTCAATTCTTGGTGT
ACCAGCAAAACAAAATCGAAAAGTAATTCAGCAATACCCAGAGCCACTTC
CTTTATTAGTGTAACGCCTTTGCCATTATGGCTAGCTATTTGTAGAGAAT
ACCGGCCAGAACATTTGAAAATCTATAAGGATTTCAACGATAAAGTAGCA
ATGACTACAAGTCCAACTTTTATGCTCATTGAAAATGAGGCTGATCCTGG
AGTTTTATATGATTCTGAAACTGGAAACTCTATAATTATTGAGATGGTTT
CCCAGGGTTTGGAAGATGCTGCGATTTTTGTTTTAAATGCATATAATAAT
AAACAGAAATCAAAATTAAACAATCAGGGAATCACTGCAACATCATTTAC
AGAATCCTTAGTTAATGTGACAAACAATTTCAAAGAATCTGTGTTCCATG
TTGCTGTTGAAAACGAACTTTTTAATCTTTGTCGATTACTTTTACAGCTT
GGAGCAGATCCAAATATCGTCAGGCGGAGACCAATAACAGCCAATAATTC
CAATAGTAAAGATGACATTTACAGCAGTTGTGATAGTATGCACTCTTATT
CCTCTTTGAAAAAAGATTCCGAATTGACTAATCATGTCAACAATGAAATA
TACGAACAAACGCAGAATGATTCTTCAGATTCCGTCATTTCATCGTGGTC
ATCAAAAACAGATGATATGAATCCATTTAAAGAATATATGAAAATAGAAA
ATGATGATTACCATTCCTTATCGTTGTCTCTGCCAATGATTCGTAAATCA
AATGCAAATAGAGGTCTTTTAATGGATTTAGCACTTGGTAAAAAGCAAAA
TAAGGAAATTCTGAAGACCACTCACCGTTGTAAAGGTAGAAAAGTCAACT
CCGATAAGCAACTGACAATTGACCTTTGCACTCCAACGCACTTGGCTGTG
AAAACGAAGAATATTAAAATTATTAATTTATTTATCTTTCATGACGAGGG
TAGAAATAAAGTAAATTGGTTAATGAATGATTATGCTGGTGAGAGCCCCT
TCACTTTGTGTTTGTGGAATGGCTTGATATCAGTTTGTGACAAGATTTTC
GAAAGATTAATCAAAACGGATTTCAAAACTTCAGAGATTGATAAAATTGT
GATAGATGAGCAGAGTTTATTGCATTTAGCCGTCAAGAAAGGTAATATTG
AAGCGGTTCAGTTTCTGATTAAAATCGGATGTGATATCAATGTCAGATCT
ATCAATAAGATGACCCCATTGCTATTAGCTACAGAGAAATCTAATATTGA
TATTGTAAGAATTTTATGCCTTTCTGGCGCAGATCCGAATATTACATCCA
ACATTATTTCACAAGAAGGTTTCATAGAACTGAATTGTCCTCTCTGGGTC
GCATTAAACAATTGCAGATTTGATATAGCTGATATTTTGGTTGAAGCTGG
AGCCGATGTTGACATGTGGTCAATACATTATAAGGACAATTATGAACAAA
CTCTTTTACATAGAACAATTTTAGAAATGAAAGAACAAGCAGCTAATTTT
TTAATTTCTCGAGGCTGTGATACTATTTCAACGATGGAAAATAAAAATCC
TTCAAATTCCATATCCAATTATGAATCCAACAATCATTACATTGAGGGAA
ATACACCTTTACATATGGCCTGTCAAATGGGGCTTGAAAGTGTTGTTAAA
AATTTGCTATCCTCTAATAAAATTGACGTAAATGTTCAAAATGCCACCGG
ATGTACATCTTTACATTTGGCTGTTAAATTTCGACATGAAGCTGTTTTAA
CTCATTTACTCAATCCGAAATATAAATTAAATTTATCTATTCGTGATCAC
CAAGGCCATACACCATTCCATACCGCGATGGAACTCTCTAATCAAAAAGC
AGCTCGGTCAATTCTGCAGTATCACCCGCAAGCAGCAGATGAAATTGATA
ATTTAGGAAGAAATTTTCTCCATGTTGCCGTTCAAACAATGAATAGAGAA
GCGGTTTATTTCCTCATTCAAGTGAATGCAAATTTAAACATCCGTGTTAA
AGACGCCTTTCAATATACTCCGTTGCATTTAGCAATCATATCAGGGGCTC
CAGAAGACTTGATACGAAGCCTGATTCTTGCTGGTGCTAACATTGCAAAT
GAAACTATAGAAAAGCAAAACCTTCTTCATCTTGCTGTCATTCATGAAAG
AGTATATATTATTAGTTTCCTTTTGGAAAATGGAGCTTCTACAAGTCATC
AAGATAACAAAATGGAGACACCCCTTCACCTGGCTGTAAGAGGAGGTAAT
GTGGATCTGATTAAACCGTTATTGGCCAATTCATCTACAACAATTAAATC
TAAAAATTTAAAGGGCGAGAATATACTGCATATTTTATCCAATAATTGTA
GAGAAAATGGTATTGTGATATTTAGTCTGATTTTAGATCATTATCCTGAG
TTTCCTGTTGATGAAAAAGATGCTTGTGGAAATACAGCTTTATTCTTGTG
TGCACTGAAAGACAATTCAAGACTGGGGGTCGCTTTATTATTGAAAGGCG
CATCATTGGGATGTTTTAATAACGAAGGATTTACACTTTTTAATAGTGAG
CACATATCAGAACAATTCATTTTAAAGTTATTAGATTCTTTAAGCAGTGA
GCCTAATTGGTTAGATGGTGAAATTTGTTTCTCGTGTCTTTGCAAGTTTT
CAATAAAAAACAGAAAACATCATTGTCGTCATTGTGGCCGTTTAGTGTGT
GGGAAATGTTCTGTTAATGAAATGCCTATCATCAAATTCAACATTAAAAA
ACCAGTTCGTGTTTGCGAAGTTTGTTTTAATTTCTTGGTCAATGGAAAAT
TTCAATAAATAATAAAACCCAATGGAATCCTATGCAAAATTTATTCAGAA
ATCTCTGGACATTTTTTTTTAATTTCTGATTTATTTATGTGATTTTATAA
GTTGTACAGAAATAG

protein sequence of SMED30030576-orf-1

>SMED30030576-orf-1 ID=SMED30030576-orf-1|Name=SMED30030576-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=383bp
SRNLNVKFKINLLNNQIMTDETLLKHFNLLQQEYHKINNKYQSLKTKYDN
LILLSGNPSTEDNFWINLNKIVRSLYKDKKFSDISIKLQKSTIPGHRIIF
EANGCEWNGSDLSNCEEINLENEEQNIGEQIVKWIYLQELNDNQNYEILW
KLMKVAHEHNLKYLKNRCESGFISKVSKDNCIYFYKKASEFSVENLRSFC
SNLIIANWNEYQPADFDGLEASIFLDLLEAQSNYPLHEAVKANRDDVVFL
YINENYSQLEELVNVISEDNELVLDLALSSKKVELCETLLKSCANLNSVD
NYGWSLLHKAIQRQDEFSCRFLIQNGCHLNPLSPDLSQTPIQLLANLIPS
HEDAEALTTINTITNLLIQNGADVNNVDNNDM*

protein sequence of SMED30030576-orf-2

>SMED30030576-orf-2 ID=SMED30030576-orf-2|Name=SMED30030576-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=978bp
MAWNYFFRTALCLAILSGNEIVMKAVLDSGRCNSINGVNSWCTSKTKSKS
NSAIPRATSFISVTPLPLWLAICREYRPEHLKIYKDFNDKVAMTTSPTFM
LIENEADPGVLYDSETGNSIIIEMVSQGLEDAAIFVLNAYNNKQKSKLNN
QGITATSFTESLVNVTNNFKESVFHVAVENELFNLCRLLLQLGADPNIVR
RRPITANNSNSKDDIYSSCDSMHSYSSLKKDSELTNHVNNEIYEQTQNDS
SDSVISSWSSKTDDMNPFKEYMKIENDDYHSLSLSLPMIRKSNANRGLLM
DLALGKKQNKEILKTTHRCKGRKVNSDKQLTIDLCTPTHLAVKTKNIKII
NLFIFHDEGRNKVNWLMNDYAGESPFTLCLWNGLISVCDKIFERLIKTDF
KTSEIDKIVIDEQSLLHLAVKKGNIEAVQFLIKIGCDINVRSINKMTPLL
LATEKSNIDIVRILCLSGADPNITSNIISQEGFIELNCPLWVALNNCRFD
IADILVEAGADVDMWSIHYKDNYEQTLLHRTILEMKEQAANFLISRGCDT
ISTMENKNPSNSISNYESNNHYIEGNTPLHMACQMGLESVVKNLLSSNKI
DVNVQNATGCTSLHLAVKFRHEAVLTHLLNPKYKLNLSIRDHQGHTPFHT
AMELSNQKAARSILQYHPQAADEIDNLGRNFLHVAVQTMNREAVYFLIQV
NANLNIRVKDAFQYTPLHLAIISGAPEDLIRSLILAGANIANETIEKQNL
LHLAVIHERVYIISFLLENGASTSHQDNKMETPLHLAVRGGNVDLIKPLL
ANSSTTIKSKNLKGENILHILSNNCRENGIVIFSLILDHYPEFPVDEKDA
CGNTALFLCALKDNSRLGVALLLKGASLGCFNNEGFTLFNSEHISEQFIL
KLLDSLSSEPNWLDGEICFSCLCKFSIKNRKHHCRHCGRLVCGKCSVNEM
PIIKFNIKKPVRVCEVCFNFLVNGKFQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005768	endosome
GO:0005769	early endosome
GO:0005829	cytosol
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0030904	retromer complex
GO:0043231	intracellular membrane-bounded organelle
GO:0044354	macropinosome

Vocabulary: **biological process**
Term	Definition
GO:0016197	endosomal transport
GO:0034058	endosomal vesicle fusion
GO:0042147	retrograde transport, endosome to Golgi
GO:0048549	positive regulation of pinocytosis
GO:0090160	Golgi to lysosome transport

Vocabulary: **molecular function**
Term	Definition
GO:0017137	Rab GTPase binding
GO:1901981	phosphatidylinositol phosphate binding
GO:0046872	metal ion binding
GO:0005515	protein binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000136	whole organism

Vocabulary: **INTERPRO**
Term	Definition
IPR036770	Ankyrin_rpt-contain_sf
IPR000306	Znf_FYVE
IPR002110	Ankyrin_rpt
IPR020683	Ankyrin_rpt-contain_dom
IPR013083	Znf_RING/FYVE/PHD
IPR017455	Znf_FYVE-rel
IPR011011	Znf_FYVE_PHD
IPR011333	SKP1/BTB/POZ_sf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000306	FYVE zinc finger	SMART	SM00064	fyve_4	coord: 907..973 e-value: 1.1E-21 score: 88.0
IPR000306	FYVE zinc finger	PFAM	PF01363	FYVE	coord: 916..969 e-value: 2.1E-13 score: 50.2
IPR002110	Ankyrin repeat	SMART	SM00248	ANK_2a	coord: 813..845 e-value: 1600.0 score: 3.4 coord: 779..809 e-value: 0.42 score: 19.7 coord: 712..742 e-value: 1.7 score: 17.6 coord: 411..440 e-value: 1.3E-4 score: 31.3 coord: 6..37 e-value: 8.0 score: 15.4 coord: 851..880 e-value: 450.0 score: 7.6 coord: 169..198 e-value: 0.2 score: 20.8 coord: 746..775 e-value: 2.3 score: 17.2 coord: 677..706 e-value: 0.22 score: 20.6 coord: 643..672 e-value: 580.0 score: 6.8 coord: 608..637 e-value: 2.7 score: 17.0 coord: 574..604 e-value: 9.6E-5 score: 31.8 coord: 523..553 e-value: 1600.0 score: 3.5 coord: 371..400 e-value: 2200.0 score: 2.4 coord: 485..514 e-value: 170.0 score: 10.8 coord: 333..362 e-value: 10.0 score: 15.0 coord: 444..473 e-value: 0.0037 score: 26.5
IPR002110	Ankyrin repeat	PFAM	PF00023	Ank	coord: 575..606 e-value: 1.7E-5 score: 25.0
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 411..443 score: 12.129
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 677..709 score: 9.404
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 444..476 score: 10.606
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 779..811 score: 9.458
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 712..745 score: 9.778
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 746..778 score: 9.885
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 574..607 score: 10.606
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 2..221 e-value: 2.3E-10 score: 42.2
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 480..563 e-value: 2.8E-7 score: 32.2
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 564..909 e-value: 2.7E-61 score: 209.4
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 292..479 e-value: 2.6E-25 score: 91.0
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 4..206
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 263..476
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 667..888
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 411..706
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 910..972 e-value: 5.8E-21 score: 76.2
IPR020683	Ankyrin repeat-containing domain	PFAM	PF12796	Ank_2	coord: 391..474 e-value: 1.1E-10 score: 41.9 coord: 613..707 e-value: 5.9E-9 score: 36.4 coord: 717..804 e-value: 1.5E-10 score: 41.5
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 333..887 score: 80.541
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 163..201 score: 8.8
None	No IPR available	PANTHER	PTHR24123:SF86		coord: 332..469
None	No IPR available	PANTHER	PTHR24123	ANKYRIN	coord: 332..469 coord: 487..974
None	No IPR available	PANTHER	PTHR24123:SF86		coord: 487..974
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..18 score: 0.591
IPR017455	Zinc finger, FYVE-related	PROSITE	PS50178	ZF_FYVE	coord: 912..972 score: 12.503
IPR011011	Zinc finger, FYVE/PHD-type	SUPERFAMILY	SSF57903	FYVE/PHD zinc finger	coord: 912..971