histone h2a.z-1

Overview


Name	histone h2a.z-1 (AFJ24840.1)
Smed ID	SMED30030543
Length (bp)	528

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of histone h2a.z-1 (SMED30030543) t-SNE clustered cells

Violin plots show distribution of expression levels for histone h2a.z-1 (SMED30030543) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of histone h2a.z-1 (SMED30030543) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for histone h2a.z-1 (SMED30030543) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030543

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30030543	SMESG000020395.1	SmedASXL_006243	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
cephalic ganglia	SMED30030543	SMESG000020395.1	dd_Smed_v4_2614_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30030543	SMESG000020395.1	dd_Smed_v4_2614_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30030543	SMESG000020395.1	dd_Smed_v6_2614_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
X1 cell	SMED30030543	SMESG000020395.1	isotig05441	be_Smed_v2	PMID:22543868 Onal et al., 2012
zeta neoblast	SMED30030543	SMESG000020395.1	dd_Smed_v4_2614_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
neoblast	SMED30030543	SMESG000020395.1	SMED_03674_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30030543	SMESG000020395.1	SMED_03674_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Human
Match: H2AZ1 (H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741])

HSP 1 Score: 210.305 bits (534), Expect = 2.554e-70
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Human
Match: H2AZ2 (H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664])

HSP 1 Score: 208.379 bits (529), Expect = 1.540e-69
Identity = 103/124 (83.06%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Human
Match: H2AZ1 (H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741])

HSP 1 Score: 203.371 bits (516), Expect = 1.115e-67
Identity = 104/122 (85.25%), Postives = 114/122 (93.44%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIA GGVIPHIHKSL+GKK
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIA-GGVIPHIHKSLIGKK 121

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Human
Match: H2AZ2 (H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664])

HSP 1 Score: 184.882 bits (468), Expect = 2.484e-60
Identity = 91/114 (79.82%), Postives = 104/114 (91.23%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHI 399
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGG+  ++
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGMYYYL 114

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Human
Match: H2AZ2 (H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664])

HSP 1 Score: 181.03 bits (458), Expect = 5.789e-59
Identity = 90/108 (83.33%), Postives = 100/108 (92.59%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGG 381
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGG
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGG 108

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Celegans
Match: htz-1 (Histone H2A.V [Source:UniProtKB/Swiss-Prot;Acc:Q27511])

HSP 1 Score: 193.741 bits (491), Expect = 5.318e-64
Identity = 98/124 (79.03%), Postives = 110/124 (88.71%), Query Frame = 1

Query:   64 MAGGK--AGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            MAGGK  AGKD+   K+K +SRS R+GLQFPVGRIHRFLK  +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHL LAIRGDEELD LIKATIAGGGVIPHIH+ L+ KK
Sbjct:    1 MAGGKGKAGKDSGKSKSKVVSRSARAGLQFPVGRIHRFLKQRTTSSGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLHLAIRGDEELDTLIKATIAGGGVIPHIHRYLMNKK 124

[Close]

Query:   64 MAGGK--AGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            MAGGK  AGKD+   K+K +SRS R+GLQFPVGRIHRFLK  +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHL LAIRGDEELD LIKATIAGGGVIPHIH+ L+ KK
Sbjct:    1 MAGGKGKAGKDSGKSKSKVVSRSARAGLQFPVGRIHRFLKQRTTSSGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLHLAIRGDEELDTLIKATIAGGGVIPHIHRYLMNKK 124

[Close]

Query:   64 MAGGK--AGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            MAGGK  AGKD+   K+K +SRS R+GLQFPVGRIHRFLK  +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHL LAIRGDEELD LIKATIAGGGVIPHIH+ L+ KK
Sbjct:    1 MAGGKGKAGKDSGKSKSKVVSRSARAGLQFPVGRIHRFLKQRTTSSGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLHLAIRGDEELDTLIKATIAGGGVIPHIHRYLMNKK 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Celegans
Match: his-35 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:Q27485])

HSP 1 Score: 126.331 bits (316), Expect = 1.216e-37
Identity = 66/108 (61.11%), Postives = 82/108 (75.93%), Query Frame = 1

Query:  112 SRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIK-ATIAGGGVIPHIHKSLVGKKPEG 432
            SRS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYL AEVLELAGNA++D K  RI+PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK  G
Sbjct:   18 SRSSRAGLQFPVGRLHRILRKGNYAQ-RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLPKKTAG 124

[Close]

Query:  112 SRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIK-ATIAGGGVIPHIHKSLVGKKPEG 432
            SRS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYL AEVLELAGNA++D K  RI+PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK  G
Sbjct:   18 SRSSRAGLQFPVGRLHRILRKGNYAQ-RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLPKKTAG 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Fly
Match: His2Av (gene:FBgn0001197 transcript:FBtr0085062)

HSP 1 Score: 209.92 bits (533), Expect = 2.809e-70
Identity = 105/128 (82.03%), Postives = 116/128 (90.62%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD 441
            MAGGKAGKD+   KAK +SRS R+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK E + D
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQD 128

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Fly
Match: His2Av (gene:FBgn0001197 transcript:FBtr0334311)

HSP 1 Score: 209.92 bits (533), Expect = 2.809e-70
Identity = 105/128 (82.03%), Postives = 116/128 (90.62%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD 441
            MAGGKAGKD+   KAK +SRS R+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK E + D
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQD 128

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Fly
Match: His2A:CG33850 (gene:FBgn0053850 transcript:FBtr0091854)

HSP 1 Score: 127.102 bits (318), Expect = 6.585e-38
Identity = 67/107 (62.62%), Postives = 81/107 (75.70%), Query Frame = 1

Query:  112 SRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIK-ATIAGGGVIPHIHKSLVGKKPE 429
            SRS R+GLQFPVGRIHR L+  +  + R+GA A VY AA++EYL AEVLELAGNA++D K  RI PRHLQLAIR DEEL+ L+   TIA GGV+P+I   L+ KK E
Sbjct:   16 SRSNRAGLQFPVGRIHRLLRKGNYAE-RVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTE 121

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Fly
Match: His2A:CG33847 (gene:FBgn0053847 transcript:FBtr0091851)

HSP 1 Score: 127.102 bits (318), Expect = 6.585e-38
Identity = 67/107 (62.62%), Postives = 81/107 (75.70%), Query Frame = 1

Query:  112 SRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIK-ATIAGGGVIPHIHKSLVGKKPE 429
            SRS R+GLQFPVGRIHR L+  +  + R+GA A VY AA++EYL AEVLELAGNA++D K  RI PRHLQLAIR DEEL+ L+   TIA GGV+P+I   L+ KK E
Sbjct:   16 SRSNRAGLQFPVGRIHRLLRKGNYAE-RVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTE 121

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Fly
Match: His2A:CG33844 (gene:FBgn0053844 transcript:FBtr0091848)

HSP 1 Score: 127.102 bits (318), Expect = 6.585e-38
Identity = 67/107 (62.62%), Postives = 81/107 (75.70%), Query Frame = 1

Query:  112 SRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIK-ATIAGGGVIPHIHKSLVGKKPE 429
            SRS R+GLQFPVGRIHR L+  +  + R+GA A VY AA++EYL AEVLELAGNA++D K  RI PRHLQLAIR DEEL+ L+   TIA GGV+P+I   L+ KK E
Sbjct:   16 SRSNRAGLQFPVGRIHRLLRKGNYAE-RVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTE 121

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Zebrafish
Match: h2az2b (H2A.Z variant histone 2b [Source:ZFIN;Acc:ZDB-GENE-050506-24])

HSP 1 Score: 209.149 bits (531), Expect = 4.402e-70
Identity = 104/124 (83.87%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Zebrafish
Match: h2az2a (H2A.Z variant histone 2a [Source:NCBI gene;Acc:252913])

HSP 1 Score: 208.379 bits (529), Expect = 9.794e-70
Identity = 103/124 (83.06%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Zebrafish
Match: h2az2b (H2A.Z variant histone 2b [Source:ZFIN;Acc:ZDB-GENE-050506-24])

HSP 1 Score: 206.453 bits (524), Expect = 5.776e-69
Identity = 103/122 (84.43%), Postives = 114/122 (93.44%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
             AGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK
Sbjct:    1 QAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKK 122

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Zebrafish
Match: hist1h2a1 (histone cluster 1 H2A family member1 [Source:ZFIN;Acc:ZDB-GENE-121214-150])

HSP 1 Score: 131.339 bits (329), Expect = 1.998e-39
Identity = 73/121 (60.33%), Postives = 89/121 (73.55%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKKPE 429
            GGKA     +AK  SRS R+GLQFPVGRIHR L+  +  + R+GA A VY AA+LEYLTAE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK E
Sbjct:    8 GGKA-----RAKAKSRSSRAGLQFPVGRIHRLLRKGNYAQ-RVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTE 122

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Zebrafish
Match: hist1h2a5 (histone cluster 1 H2A family member 5 [Source:ZFIN;Acc:ZDB-GENE-131121-77])

HSP 1 Score: 130.954 bits (328), Expect = 2.595e-39
Identity = 73/124 (58.87%), Postives = 89/124 (71.77%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPEGLT 438
            G   GK   KAKT  RS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYLTAE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK E  T
Sbjct:    5 GKTGGKTRAKAKT--RSSRAGLQFPVGRVHRLLRKGNYAQ-RVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAT 125

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Xenopus
Match: arrdc2 (arrestin domain containing 2 [Source:Xenbase;Acc:XB-GENE-946088])

HSP 1 Score: 208.379 bits (529), Expect = 1.396e-69
Identity = 103/124 (83.06%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Xenopus
Match: h2a.zl (H2A.Z variant histone 1 [Source:NCBI gene;Acc:448675])

HSP 1 Score: 207.994 bits (528), Expect = 2.139e-69
Identity = 104/124 (83.87%), Postives = 114/124 (91.94%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAK--TISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKDT KAK  +I+RS R+GLQFPVGRIHR LK+ +++ GR+G TAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDTGKAKATSITRSSRAGLQFPVGRIHRLLKNRTTSHGRVGGTAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDALIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Xenopus
Match: h2a.zl (H2A.Z variant histone 1 [Source:NCBI gene;Acc:448675])

HSP 1 Score: 204.527 bits (519), Expect = 4.905e-68
Identity = 103/123 (83.74%), Postives = 113/123 (91.87%), Query Frame = 1

Query:   67 AGGKAGKDTCKAK--TISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            AGGKAGKDT KAK  +I+RS R+GLQFPVGRIHR LK+ +++ GR+G TAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    3 AGGKAGKDTGKAKATSITRSSRAGLQFPVGRIHRLLKNRTTSHGRVGGTAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDALIKATIAGGGVIPHIHKSLIGKKGQ 125

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Xenopus
Match: cited4 (Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 4 [Source:Xenbase;Acc:XB-GENE-946639])

HSP 1 Score: 133.65 bits (335), Expect = 4.434e-40
Identity = 74/129 (57.36%), Postives = 91/129 (70.54%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPEGLTD*FKC 453
            G + GK   KAKT  RS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYLTAE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK E     FK 
Sbjct:    5 GKQGGKTRAKAKT--RSSRAGLQFPVGRVHRLLRKGNYAE-RVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLPKKTESTKAYFKA 130

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Xenopus
Match: ENSXETT00000002762.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:125293331:125293968:-1 gene:ENSXETG00000000652.1 transcript:ENSXETT00000002762.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 133.65 bits (335), Expect = 4.434e-40
Identity = 74/129 (57.36%), Postives = 91/129 (70.54%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPEGLTD*FKC 453
            G + GK   KAKT  RS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYLTAE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK E     FK 
Sbjct:    5 GKQGGKTRAKAKT--RSSRAGLQFPVGRVHRLLRKGNYAE-RVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLPKKTESTKAYFKA 130

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Mouse
Match: H2az1 (H2A.Z variant histone 1 [Source:MGI Symbol;Acc:MGI:1888388])

HSP 1 Score: 210.305 bits (534), Expect = 1.753e-70
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Mouse
Match: H2az2 (H2A.Z histone variant 2 [Source:MGI Symbol;Acc:MGI:1924855])

HSP 1 Score: 208.379 bits (529), Expect = 1.057e-69
Identity = 103/124 (83.06%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Mouse
Match: H2az1 (H2A.Z variant histone 1 [Source:MGI Symbol;Acc:MGI:1888388])

HSP 1 Score: 152.91 bits (385), Expect = 3.286e-48
Identity = 83/124 (66.94%), Postives = 93/124 (75.00%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAE                       LAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAE-----------------------LAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 101

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Mouse
Match: H2ac1 (H2A clustered histone 1 [Source:MGI Symbol;Acc:MGI:2448285])

HSP 1 Score: 136.346 bits (342), Expect = 2.907e-41
Identity = 75/121 (61.98%), Postives = 91/121 (75.21%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPE 429
            GGKA     +AK  SRS R+GLQFPVGR+HR L+  +  + RIGA A VY AA+LEYLTAEVLELAGNA++D K  RI+PRHLQLAIR DEEL+ L+ + TIA GGV+P+I   L+ KK E
Sbjct:    8 GGKA-----RAKVKSRSSRAGLQFPVGRVHRLLRQGNYAQ-RIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTE 122

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Mouse
Match: H2ac20 (H2A clustered histone 20 [Source:MGI Symbol;Acc:MGI:2448316])

HSP 1 Score: 134.42 bits (337), Expect = 1.412e-40
Identity = 74/121 (61.16%), Postives = 90/121 (74.38%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPE 429
            G + GK   KAK  SRS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYLTAE+LELAGNA++D K  RI PRHLQLAIR DEEL+ L+ K TIA GGV+P+I   L+ KK E
Sbjct:    5 GKQGGKARAKAK--SRSSRAGLQFPVGRVHRLLRKGNYAE-RVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTE 122

[Close]

BLAST of histone h2a.z-1 vs. UniProt/SwissProt
Match: sp|Q6YNC8|H2AZ_SHEEP (Histone H2A.Z OS=Ovis aries OX=9940 GN=H2AZ1 PE=2 SV=3)

HSP 1 Score: 210.305 bits (534), Expect = 1.226e-69
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. UniProt/SwissProt
Match: sp|P0C0S7|H2AZ_RAT (Histone H2A.Z OS=Rattus norvegicus OX=10116 GN=H2az1 PE=1 SV=2)

HSP 1 Score: 210.305 bits (534), Expect = 1.226e-69
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. UniProt/SwissProt
Match: sp|Q5RC42|H2AZ_PONAB (Histone H2A.Z OS=Pongo abelii OX=9601 GN=H2AZ1 PE=2 SV=3)

HSP 1 Score: 210.305 bits (534), Expect = 1.226e-69
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. UniProt/SwissProt
Match: sp|P22647|H2AZ_ONCMY (Histone H2A.Z OS=Oncorhynchus mykiss OX=8022 GN=h2az1 PE=1 SV=4)

HSP 1 Score: 210.305 bits (534), Expect = 1.226e-69
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. UniProt/SwissProt
Match: sp|P0C0S6|H2AZ_MOUSE (Histone H2A.Z OS=Mus musculus OX=10090 GN=H2az1 PE=1 SV=2)

HSP 1 Score: 210.305 bits (534), Expect = 1.226e-69
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. TrEMBL
Match: I1ZII6 (Histone H2A OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 253.832 bits (647), Expect = 2.013e-84
Identity = 126/126 (100.00%), Postives = 126/126 (100.00%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD 441
            MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD
Sbjct:    1 MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD 126

[Close]

BLAST of histone h2a.z-1 vs. TrEMBL
Match: K9IQB8 (Histone H2A (Fragment) OS=Desmodus rotundus OX=9430 PE=2 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 2.861e-68
Identity = 107/128 (83.59%), Postives = 118/128 (92.19%), Query Frame = 1

Query:   46 SSTLF*MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            +S  F MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK
Sbjct:    1 ASAEFEMAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKK 128

[Close]

BLAST of histone h2a.z-1 vs. TrEMBL
Match: A0A1B3IQX3 (Histone H2A OS=Hydractinia echinata OX=35630 PE=2 SV=1)

HSP 1 Score: 213.001 bits (541), Expect = 3.266e-68
Identity = 106/121 (87.60%), Postives = 115/121 (95.04%), Query Frame = 1

Query:   64 MAGGKAGKDT-CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            MAGGKAGKD+  K K+ SRS R+GLQFPVGRIHR+LKS S+NKGR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELD+LIKATIAGGGVIPHIHKSL+GKK
Sbjct:    1 MAGGKAGKDSKPKTKSTSRSARAGLQFPVGRIHRYLKSRSTNKGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDLLIKATIAGGGVIPHIHKSLIGKK 121

[Close]

BLAST of histone h2a.z-1 vs. TrEMBL
Match: T2MHP0 (Histone H2A OS=Hydra vulgaris OX=6087 GN=H2AFZ PE=2 SV=1)

HSP 1 Score: 210.69 bits (535), Expect = 2.013e-67
Identity = 105/121 (86.78%), Postives = 114/121 (94.21%), Query Frame = 1

Query:   64 MAGGKAGKDT-CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            MAGGKAGKD+  K K+ SRS R+GLQFPVGRIHR+LKS S+NKGR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELD+LIKATIAGGGVIPHIHKSL+ KK
Sbjct:    1 MAGGKAGKDSKPKTKSTSRSARAGLQFPVGRIHRYLKSRSTNKGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDLLIKATIAGGGVIPHIHKSLMNKK 121

[Close]

BLAST of histone h2a.z-1 vs. TrEMBL
Match: H0W952 (Histone H2A OS=Cavia porcellus OX=10141 GN=H2AFZ PE=3 SV=1)

HSP 1 Score: 210.69 bits (535), Expect = 2.172e-67
Identity = 105/124 (84.68%), Postives = 116/124 (93.55%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ KAKT  +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKTKGVSRSQRAGLQFPVGRIHRLLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Cavefish
Match: H2AZ1 (histone H2A.Z [Source:NCBI gene;Acc:103038819])

HSP 1 Score: 209.149 bits (531), Expect = 3.571e-70
Identity = 104/124 (83.87%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Cavefish
Match: h2az2a (histone H2A.V [Source:NCBI gene;Acc:103037668])

HSP 1 Score: 208.379 bits (529), Expect = 8.301e-70
Identity = 103/124 (83.06%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Cavefish
Match: h2az2b (histone H2A.V [Source:NCBI gene;Acc:103039302])

HSP 1 Score: 207.994 bits (528), Expect = 9.061e-70
Identity = 103/124 (83.06%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Cavefish
Match: h2az2a (histone H2A.V [Source:NCBI gene;Acc:103037668])

HSP 1 Score: 204.912 bits (520), Expect = 2.216e-68
Identity = 102/122 (83.61%), Postives = 113/122 (92.62%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
             AGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK
Sbjct:    7 QAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKK 128

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Cavefish
Match: h2az2b (histone H2A.V [Source:NCBI gene;Acc:103039302])

HSP 1 Score: 194.512 bits (493), Expect = 1.830e-64
Identity = 94/112 (83.93%), Postives = 105/112 (93.75%), Query Frame = 1

Query:   94 CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
             KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    4 AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 115

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BLAST of histone h2a.z-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005338.1 (pep scaffold:Pmarinus_7.0:GL476820:708214:709027:-1 gene:ENSPMAG00000004859.1 transcript:ENSPMAT00000005338.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 128.642 bits (322), Expect = 4.091e-39
Identity = 70/119 (58.82%), Postives = 87/119 (73.11%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKK 423
            G   GK   KAK  SRS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK
Sbjct:    5 GKTGGKSRAKAK--SRSSRAGLQFPVGRVHRLLRKGNYAQ-RVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLMGGVTIAQGGVLPNIQAVLLPKK 120

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BLAST of histone h2a.z-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011253.1 (pep scaffold:Pmarinus_7.0:GL479154:926813:927238:-1 gene:ENSPMAG00000010226.1 transcript:ENSPMAT00000011253.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 128.642 bits (322), Expect = 5.263e-39
Identity = 71/119 (59.66%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKK 423
            GGKA     +AK  SRS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLAIR DEEL+ L+   TIA GGV+P+I   L+ KK
Sbjct:    8 GGKA-----RAKAKSRSSRAGLQFPVGRVHRLLRKGNYAE-RVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKK 120

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BLAST of histone h2a.z-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002388.1 (pep scaffold:Pmarinus_7.0:GL476925:193851:194294:1 gene:ENSPMAG00000002177.1 transcript:ENSPMAT00000002388.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.872 bits (320), Expect = 8.578e-39
Identity = 70/119 (58.82%), Postives = 87/119 (73.11%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKK 423
            G   GK   KAK  SRS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK
Sbjct:    5 GKTGGKSRAKAK--SRSSRAGLQFPVGRVHRLLRKGNYAQ-RVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLMGGVTIAQGGVLPNIQAVLLPKK 120

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BLAST of histone h2a.z-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011166.1 (pep scaffold:Pmarinus_7.0:GL476820:1027708:1028088:1 gene:ENSPMAG00000010139.1 transcript:ENSPMAT00000011166.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.102 bits (318), Expect = 1.400e-38
Identity = 72/120 (60.00%), Postives = 87/120 (72.50%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFL-KSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKK 423
            G   GK   KAK  SRS R+GLQFPVGR+HR L K N +   R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK
Sbjct:    5 GKTGGKSRAKAK--SRSSRAGLQFPVGRVHRLLCKGNYAQ--RVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLMGGVTIAQGGVLPNIQAVLLPKK 120

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BLAST of histone h2a.z-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011070.1 (pep scaffold:Pmarinus_7.0:GL476925:253954:254352:-1 gene:ENSPMAG00000010041.1 transcript:ENSPMAT00000011070.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 124.02 bits (310), Expect = 2.765e-37
Identity = 69/123 (56.10%), Postives = 88/123 (71.54%), Query Frame = 1

Query:   64 MAG-GKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKKP 426
            M+G GK G  + +AK  SRS R+GLQFPVGRIHR L+  +  + R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P        ++P
Sbjct:    1 MSGRGKTGGKS-RAKAKSRSSRAGLQFPVGRIHRLLRKGNYAQ-RVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLMGGVTIAQGGVLPTSRPCCCPRRP 121

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BLAST of histone h2a.z-1 vs. Ensembl Yeast
Match: HTZ1 (Histone variant H2AZ; exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin; Htz1p-containing nucleosomes facilitate RNA Pol II passage by affecting correct assembly and modification status of RNA Pol II elongation complexes and by favoring efficient nucleosome remodeling [Source:SGD;Acc:S000005372])

HSP 1 Score: 154.451 bits (389), Expect = 2.642e-49
Identity = 77/115 (66.96%), Postives = 99/115 (86.09%), Query Frame = 1

Query:   73 GKAG-KDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLV 414
            GK+G KD+   ++ S S R+GLQFPVGRI R+LK +++ + R+G+ AA+Y  A+LEYLTAEVLELAGNA+KDLKVKRI+PRHLQLAIRGD+ELD LI+ATIA GGV+PHI+K+L+
Sbjct:   10 GKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALL 124

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BLAST of histone h2a.z-1 vs. Ensembl Yeast
Match: HTA2 (Histone H2A; core histone protein required for chromatin assembly and chromosome function; one of two nearly identical (see also HTA1) subtypes; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p [Source:SGD;Acc:S000000099])

HSP 1 Score: 122.479 bits (306), Expect = 7.451e-37
Identity = 62/105 (59.05%), Postives = 81/105 (77.14%), Query Frame = 1

Query:  112 SRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKK 423
            SRS ++GL FPVGR+HR L+  +  + RIG+ A VY  A+LEYL AE+LELAGNA++D K  RI PRHLQLAIR D+EL+ L+   TIA GGV+P+IH++L+ KK
Sbjct:   18 SRSAKAGLTFPVGRVHRLLRRGNYAQ-RIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKK 121

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Yeast
Match: HTA1 (Histone H2A; core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p; N-terminally propionylated in vivo [Source:SGD;Acc:S000002633])

HSP 1 Score: 122.479 bits (306), Expect = 7.451e-37
Identity = 62/105 (59.05%), Postives = 81/105 (77.14%), Query Frame = 1

Query:  112 SRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKK 423
            SRS ++GL FPVGR+HR L+  +  + RIG+ A VY  A+LEYL AE+LELAGNA++D K  RI PRHLQLAIR D+EL+ L+   TIA GGV+P+IH++L+ KK
Sbjct:   18 SRSAKAGLTFPVGRVHRLLRRGNYAQ-RIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKK 121

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BLAST of histone h2a.z-1 vs. Ensembl Nematostella
Match: EDO46289 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RQH8])

HSP 1 Score: 205.297 bits (521), Expect = 4.636e-69
Identity = 102/121 (84.30%), Postives = 113/121 (93.39%), Query Frame = 1

Query:   64 MAGGKAGKDT-CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            MAGGKAGKD+  KAK +SRS R+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK
Sbjct:    1 MAGGKAGKDSKAKAKAVSRSARAGLQFPVGRIHRHLKNRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKK 121

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BLAST of histone h2a.z-1 vs. Ensembl Nematostella
Match: EDO34611 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7SNV0])

HSP 1 Score: 133.65 bits (335), Expect = 7.283e-41
Identity = 74/124 (59.68%), Postives = 92/124 (74.19%), Query Frame = 1

Query:   64 MAG-GKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKKPE 429
            M+G GK GK   K K  SRS R+GLQFPVGR+HRFL+  +  + R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK E
Sbjct:    1 MSGRGKGGKSRAKGK--SRSARAGLQFPVGRVHRFLRKGNYAE-RVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNRLLHGVTIAQGGVLPNIQAVLLPKKSE 121

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BLAST of histone h2a.z-1 vs. Ensembl Nematostella
Match: EDO31130 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7SYT5])

HSP 1 Score: 133.265 bits (334), Expect = 1.256e-40
Identity = 73/124 (58.87%), Postives = 92/124 (74.19%), Query Frame = 1

Query:   64 MAG-GKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKKPE 429
            M+G GK GK   K K  SRS R+GLQFPVGR+HRFL+  +  + R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ K+ E
Sbjct:    1 MSGRGKGGKSRAKGK--SRSARAGLQFPVGRVHRFLRKGNYAE-RVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKRSE 121

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BLAST of histone h2a.z-1 vs. Ensembl Nematostella
Match: EDO49641 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RFQ0])

HSP 1 Score: 133.65 bits (335), Expect = 1.262e-40
Identity = 72/121 (59.50%), Postives = 91/121 (75.21%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKK 423
            M+G   GK   K+K  +RS R+GLQFPVGRIHRFL+  +  + R+GA A VY AA+LEYLTAE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L++  TIA GGV+P+I   L+ KK
Sbjct:    1 MSGRGKGK-INKSKVKTRSSRAGLQFPVGRIHRFLRKGNYAE-RVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKSRIVPRHLQLAVRNDEELNKLLQGVTIAQGGVLPNIQAVLLPKK 119

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BLAST of histone h2a.z-1 vs. Ensembl Nematostella
Match: EDO46356 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RQF5])

HSP 1 Score: 132.494 bits (332), Expect = 2.388e-40
Identity = 73/124 (58.87%), Postives = 92/124 (74.19%), Query Frame = 1

Query:   64 MAG-GKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKA-TIAGGGVIPHIHKSLVGKKPE 429
            M+G GK GK   K K  SRS ++GLQFPVGR+HRFL+  +  K R+GA A VY AA+LEYL+AE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TI+ GGV+P+I   L+ KK E
Sbjct:    1 MSGRGKGGKSRAKGK--SRSAKAGLQFPVGRVHRFLRKGNYAK-RVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNRLLHGVTISQGGVLPNIQAVLLPKKSE 121

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BLAST of histone h2a.z-1 vs. Ensembl Medaka
Match: H2AFZ (histone H2A.Z [Source:NCBI gene;Acc:101172846])

HSP 1 Score: 208.764 bits (530), Expect = 4.984e-70
Identity = 105/124 (84.68%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKT--ISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+ K KT  ISRSQR+GLQFPVGRIHR LKS +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKTKTKAISRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

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BLAST of histone h2a.z-1 vs. Ensembl Medaka
Match: h2az2a (histone H2A.V [Source:NCBI gene;Acc:101170644])

HSP 1 Score: 208.379 bits (529), Expect = 8.249e-70
Identity = 103/124 (83.06%), Postives = 115/124 (92.74%), Query Frame = 1

Query:   64 MAGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
            MAGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    1 MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 124

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Medaka
Match: h2az2a (histone H2A.V [Source:NCBI gene;Acc:101170644])

HSP 1 Score: 204.527 bits (519), Expect = 8.340e-66
Identity = 102/121 (84.30%), Postives = 113/121 (93.39%), Query Frame = 1

Query:   67 AGGKAGKDT--CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKK 423
            AGGKAGKD+   KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK
Sbjct:  190 AGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKK 310

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Medaka
Match: h2az2a (histone H2A.V [Source:NCBI gene;Acc:101170644])

HSP 1 Score: 194.897 bits (494), Expect = 1.590e-64
Identity = 94/112 (83.93%), Postives = 105/112 (93.75%), Query Frame = 1

Query:   94 CKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPE 429
             KAK +SRSQR+GLQFPVGRIHR LK+ +++ GR+GATAAVY+AAILEYLTAEVLELAGNASKDLKVKRI+PRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKK +
Sbjct:    8 AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQ 119

[Close]

BLAST of histone h2a.z-1 vs. Ensembl Medaka
Match: ENSORLT00000043619.1 (pep primary_assembly:ASM223467v1:1:2176285:2181192:1 gene:ENSORLG00000022228.1 transcript:ENSORLT00000043619.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.568 bits (327), Expect = 3.990e-39
Identity = 72/121 (59.50%), Postives = 88/121 (72.73%), Query Frame = 1

Query:   70 GGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPE 429
            G   GK   KAKT  RS R+GLQFPVGR+HR L+  +  + R+GA A VY AA+LEYLTAE+LELAGNA++D K  RI PRHLQLA+R DEEL+ L+   TIA GGV+P+I   L+ KK E
Sbjct:    5 GKTGGKARAKAKT--RSSRAGLQFPVGRVHRLLRKGNYAE-RVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTE 122

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BLAST of histone h2a.z-1 vs. Planmine SMEST
Match: SMESG000020395.1 (SMESG000020395.1)

HSP 1 Score: 253.832 bits (647), Expect = 5.598e-88
Identity = 126/126 (100.00%), Postives = 126/126 (100.00%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD 441
            MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD
Sbjct:    1 MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKPEGLTD 126

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BLAST of histone h2a.z-1 vs. Planmine SMEST
Match: SMESG000074553.1 (SMESG000074553.1)

HSP 1 Score: 169.474 bits (428), Expect = 1.312e-54
Identity = 102/123 (82.93%), Postives = 111/123 (90.24%), Query Frame = 1

Query:   64 MAGGKAGKDTCKAKTISRS--QRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIKATIAGGGVIPHIHKSLVGKKP 426
            MA GKAGKD+ K+K+ S S   R+GLQFPVGRIHR LKS +++ GR+GATAAVY AAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELD LIKATIAGGGVIPHIHKSL+GKKP
Sbjct:    1 MAKGKAGKDSGKSKSKSISRSHRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYAAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDTLIKATIAGGGVIPHIHKSLIGKKP 123

[Close]

BLAST of histone h2a.z-1 vs. Planmine SMEST
Match: SMESG000006040.1 (SMESG000006040.1)

HSP 1 Score: 137.502 bits (345), Expect = 5.596e-42
Identity = 77/122 (63.11%), Postives = 94/122 (77.05%), Query Frame = 1

Query:   67 AGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPE 429
            A GKAGK T K+++ +RS R+GLQFPVGRIHR L+  +  + R+GA A VY AA+LEYL AEVLELAGNA++D K  RI PRHLQLAIR DEEL+ L+ K TIA GGV+P+I  SL+ KK E
Sbjct:    3 AKGKAGK-TTKSQSKTRSSRAGLQFPVGRIHRKLRKGNFAE-RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQISLLPKKAE 122

[Close]

BLAST of histone h2a.z-1 vs. Planmine SMEST
Match: SMESG000006040.1 (SMESG000006040.1)

HSP 1 Score: 137.117 bits (344), Expect = 5.750e-42
Identity = 77/122 (63.11%), Postives = 94/122 (77.05%), Query Frame = 1

Query:   67 AGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKKPE 429
            A GKAGK T K+++ +RS R+GLQFPVGRIHR L+  +  + R+GA A VY AA+LEYL AEVLELAGNA++D K  RI PRHLQLAIR DEEL+ L+ K TIA GGV+P+I  SL+ KK E
Sbjct:    3 AKGKAGK-TTKSQSKTRSSRAGLQFPVGRIHRKLRKGNFAE-RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQISLLPKKAE 122

[Close]

BLAST of histone h2a.z-1 vs. Planmine SMEST
Match: SMESG000018807.1 (SMESG000018807.1)

HSP 1 Score: 132.109 bits (331), Expect = 7.634e-40
Identity = 76/122 (62.30%), Postives = 90/122 (73.77%), Query Frame = 1

Query:   64 MAG-GKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAAVYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLI-KATIAGGGVIPHIHKSLVGKK 423
            M+G GK GK   KAK  SRS R+GLQFPVGRIHR L+  +  + R+GA A VY AA+LEYL AEVLELAGNA++D K  RI PRHLQLAIR DEEL+ L+   TIA GGV+P+I   L+ KK
Sbjct:    1 MSGRGKGGKSRNKAK--SRSVRAGLQFPVGRIHRMLRKGNYAE-RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLPKK 119

The following BLAST results are available for this feature:

BLAST of histone h2a.z-1 vs. Ensembl Human
BLAST of histone h2a.z-1 vs. Ensembl Celegans
BLAST of histone h2a.z-1 vs. Ensembl Fly
BLAST of histone h2a.z-1 vs. Ensembl Zebrafish
BLAST of histone h2a.z-1 vs. Ensembl Xenopus
BLAST of histone h2a.z-1 vs. Ensembl Mouse
BLAST of histone h2a.z-1 vs. UniProt/SwissProt
BLAST of histone h2a.z-1 vs. TrEMBL
BLAST of histone h2a.z-1 vs. Ensembl Cavefish
BLAST of histone h2a.z-1 vs. Ensembl Sea Lamprey
BLAST of histone h2a.z-1 vs. Ensembl Yeast
BLAST of histone h2a.z-1 vs. Ensembl Nematostella
BLAST of histone h2a.z-1 vs. Ensembl Medaka
BLAST of histone h2a.z-1 vs. Planmine SMEST

BLAST of histone h2a.z-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
H2AZ1	2.554e-70	84.68	H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HG...	[more]
H2AZ2	1.540e-69	83.06	H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HG...	[more]
H2AZ1	1.115e-67	85.25	H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HG...	[more]
H2AZ2	2.484e-60	79.82	H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HG...	[more]
H2AZ2	5.789e-59	83.33	H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of histone h2a.z-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
htz-1	5.318e-64	79.03	Histone H2A.V [Source:UniProtKB/Swiss-Prot;Acc:Q2...	[more]
htz-1	5.318e-64	79.03	Histone H2A.V [Source:UniProtKB/Swiss-Prot;Acc:Q2...	[more]
htz-1	5.318e-64	79.03	Histone H2A.V [Source:UniProtKB/Swiss-Prot;Acc:Q2...	[more]
his-35	1.216e-37	61.11	Histone H2A [Source:UniProtKB/TrEMBL;Acc:Q27485]	[more]
his-35	1.216e-37	61.11	Histone H2A [Source:UniProtKB/TrEMBL;Acc:Q27485]	[more]

BLAST of histone h2a.z-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
His2Av	2.809e-70	82.03	gene:FBgn0001197 transcript:FBtr0085062	[more]
His2Av	2.809e-70	82.03	gene:FBgn0001197 transcript:FBtr0334311	[more]
His2A:CG33850	6.585e-38	62.62	gene:FBgn0053850 transcript:FBtr0091854	[more]
His2A:CG33847	6.585e-38	62.62	gene:FBgn0053847 transcript:FBtr0091851	[more]
His2A:CG33844	6.585e-38	62.62	gene:FBgn0053844 transcript:FBtr0091848	[more]

BLAST of histone h2a.z-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
h2az2b	4.402e-70	83.87	H2A.Z variant histone 2b [Source:ZFIN;Acc:ZDB-GENE...	[more]
h2az2a	9.794e-70	83.06	H2A.Z variant histone 2a [Source:NCBI gene;Acc:252...	[more]
h2az2b	5.776e-69	84.43	H2A.Z variant histone 2b [Source:ZFIN;Acc:ZDB-GENE...	[more]
hist1h2a1	1.998e-39	60.33	histone cluster 1 H2A family member1 [Source:ZFIN;...	[more]
hist1h2a5	2.595e-39	58.87	histone cluster 1 H2A family member 5 [Source:ZFIN...	[more]

BLAST of histone h2a.z-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arrdc2	1.396e-69	83.06	arrestin domain containing 2 [Source:Xenbase;Acc:X...	[more]
h2a.zl	2.139e-69	83.87	H2A.Z variant histone 1 [Source:NCBI gene;Acc:4486...	[more]
h2a.zl	4.905e-68	83.74	H2A.Z variant histone 1 [Source:NCBI gene;Acc:4486...	[more]
cited4	4.434e-40	57.36	Cbp/p300-interacting transactivator, with Glu/Asp ...	[more]
ENSXETT00000002762.1	4.434e-40	57.36	pep primary_assembly:Xenopus_tropicalis_v9.1:3:125...	[more]

BLAST of histone h2a.z-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
H2az1	1.753e-70	84.68	H2A.Z variant histone 1 [Source:MGI Symbol;Acc:MGI...	[more]
H2az2	1.057e-69	83.06	H2A.Z histone variant 2 [Source:MGI Symbol;Acc:MGI...	[more]
H2az1	3.286e-48	66.94	H2A.Z variant histone 1 [Source:MGI Symbol;Acc:MGI...	[more]
H2ac1	2.907e-41	61.98	H2A clustered histone 1 [Source:MGI Symbol;Acc:MGI...	[more]
H2ac20	1.412e-40	61.16	H2A clustered histone 20 [Source:MGI Symbol;Acc:MG...	[more]

BLAST of histone h2a.z-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6YNC8\|H2AZ_SHEEP	1.226e-69	84.68	Histone H2A.Z OS=Ovis aries OX=9940 GN=H2AZ1 PE=2 ...	[more]
sp\|P0C0S7\|H2AZ_RAT	1.226e-69	84.68	Histone H2A.Z OS=Rattus norvegicus OX=10116 GN=H2a...	[more]
sp\|Q5RC42\|H2AZ_PONAB	1.226e-69	84.68	Histone H2A.Z OS=Pongo abelii OX=9601 GN=H2AZ1 PE=...	[more]
sp\|P22647\|H2AZ_ONCMY	1.226e-69	84.68	Histone H2A.Z OS=Oncorhynchus mykiss OX=8022 GN=h2...	[more]
sp\|P0C0S6\|H2AZ_MOUSE	1.226e-69	84.68	Histone H2A.Z OS=Mus musculus OX=10090 GN=H2az1 PE...	[more]

BLAST of histone h2a.z-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZII6	2.013e-84	100.00	Histone H2A OS=Schmidtea mediterranea OX=79327 PE=...	[more]
K9IQB8	2.861e-68	83.59	Histone H2A (Fragment) OS=Desmodus rotundus OX=943...	[more]
A0A1B3IQX3	3.266e-68	87.60	Histone H2A OS=Hydractinia echinata OX=35630 PE=2 ...	[more]
T2MHP0	2.013e-67	86.78	Histone H2A OS=Hydra vulgaris OX=6087 GN=H2AFZ PE=...	[more]
H0W952	2.172e-67	84.68	Histone H2A OS=Cavia porcellus OX=10141 GN=H2AFZ P...	[more]

BLAST of histone h2a.z-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
H2AZ1	3.571e-70	83.87	histone H2A.Z [Source:NCBI gene;Acc:103038819]	[more]
h2az2a	8.301e-70	83.06	histone H2A.V [Source:NCBI gene;Acc:103037668]	[more]
h2az2b	9.061e-70	83.06	histone H2A.V [Source:NCBI gene;Acc:103039302]	[more]
h2az2a	2.216e-68	83.61	histone H2A.V [Source:NCBI gene;Acc:103037668]	[more]
h2az2b	1.830e-64	83.93	histone H2A.V [Source:NCBI gene;Acc:103039302]	[more]

BLAST of histone h2a.z-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000005338.1	4.091e-39	58.82	pep scaffold:Pmarinus_7.0:GL476820:708214:709027:-...	[more]
ENSPMAT00000011253.1	5.263e-39	59.66	pep scaffold:Pmarinus_7.0:GL479154:926813:927238:-...	[more]
ENSPMAT00000002388.1	8.578e-39	58.82	pep scaffold:Pmarinus_7.0:GL476925:193851:194294:1...	[more]
ENSPMAT00000011166.1	1.400e-38	60.00	pep scaffold:Pmarinus_7.0:GL476820:1027708:1028088...	[more]
ENSPMAT00000011070.1	2.765e-37	56.10	pep scaffold:Pmarinus_7.0:GL476925:253954:254352:-...	[more]

BLAST of histone h2a.z-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
HTZ1	2.642e-49	66.96	Histone variant H2AZ; exchanged for histone H2A in...	[more]
HTA2	7.451e-37	59.05	Histone H2A; core histone protein required for chr...	[more]
HTA1	7.451e-37	59.05	Histone H2A; core histone protein required for chr...	[more]

BLAST of histone h2a.z-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46289	4.636e-69	84.30	Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RQH8]	[more]
EDO34611	7.283e-41	59.68	Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7SNV0]	[more]
EDO31130	1.256e-40	58.87	Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7SYT5]	[more]
EDO49641	1.262e-40	59.50	Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RFQ0]	[more]
EDO46356	2.388e-40	58.87	Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RQF5]	[more]

BLAST of histone h2a.z-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
H2AFZ	4.984e-70	84.68	histone H2A.Z [Source:NCBI gene;Acc:101172846]	[more]
h2az2a	8.249e-70	83.06	histone H2A.V [Source:NCBI gene;Acc:101170644]	[more]
h2az2a	8.340e-66	84.30	histone H2A.V [Source:NCBI gene;Acc:101170644]	[more]
h2az2a	1.590e-64	83.93	histone H2A.V [Source:NCBI gene;Acc:101170644]	[more]
ENSORLT00000043619.1	3.990e-39	59.50	pep primary_assembly:ASM223467v1:1:2176285:2181192...	[more]

BLAST of histone h2a.z-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000020395.1	5.598e-88	100.00	SMESG000020395.1	[more]
SMESG000074553.1	1.312e-54	82.93	SMESG000074553.1	[more]
SMESG000006040.1	5.596e-42	63.11	SMESG000006040.1	[more]
SMESG000006040.1	5.750e-42	63.11	SMESG000006040.1	[more]
SMESG000018807.1	7.634e-40	62.30	SMESG000018807.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30030543
GenBank	AFJ24840.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030543 ID=SMED30030543|Name=histone h2a.z-1|organism=Schmidtea mediterranea sexual|type=transcript|length=528bp
TAATTTTTTAACTATTATTATTGTTTATATAGGTTGATATTTTAAAGCTC
AACATTATTTTAAATGGCAGGTGGAAAAGCAGGAAAAGATACTTGTAAAG
CTAAAACTATTTCTAGATCACAAAGATCTGGATTACAATTTCCTGTTGGT
CGTATTCACAGGTTTTTGAAATCGAATTCATCCAACAAAGGACGTATTGG
AGCAACAGCTGCAGTTTACACTGCCGCTATACTTGAATATTTGACAGCTG
AAGTGTTGGAATTAGCTGGAAATGCCAGCAAAGATTTAAAAGTTAAACGT
ATTTCCCCTCGCCATTTGCAATTGGCAATCCGAGGAGATGAAGAACTTGA
CGTTTTAATTAAAGCCACTATTGCTGGCGGTGGAGTTATTCCTCATATTC
ATAAAAGTCTTGTTGGTAAAAAGCCAGAGGGTCTTACAGATTGATTTAAA
TGTATATAAAATAGAATTTAATGTTATTATATTGTTGTTAAATATGTATG
TGTATTTATAAATAAACAATGTTTTCCC

protein sequence of SMED30030543-orf-1

>SMED30030543-orf-1 ID=SMED30030543-orf-1|Name=SMED30030543-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=127bp
MAGGKAGKDTCKAKTISRSQRSGLQFPVGRIHRFLKSNSSNKGRIGATAA
VYTAAILEYLTAEVLELAGNASKDLKVKRISPRHLQLAIRGDEELDVLIK
ATIAGGGVIPHIHKSLVGKKPEGLTD*

Aliases

The feature 'histone h2a.z-1' has the following synonyms


Synonym
h2a.z-1

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000420	parapharyngeal region
PLANA:0000429	neoblast
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR002119	Histone_H2A
IPR007125	Histone_H2A/H2B/H3
IPR032454	Histone_H2A_C
IPR009072	Histone-fold

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0046982	protein heterodimerization activity

Vocabulary: **cellular component**
Term	Definition
GO:0000786	nucleosome
GO:0005634	nucleus
GO:0005694	chromosome

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002119	Histone H2A	PRINTS	PR00620	HISTONEH2A	coord: 14..36 score: 66.67 coord: 100..118 score: 52.33 coord: 44..59 score: 68.69 coord: 73..87 score: 64.51 coord: 59..72 score: 84.63
IPR002119	Histone H2A	SMART	SM00414	h2a4	coord: 3..123 e-value: 7.7E-67 score: 238.0
IPR002119	Histone H2A	CDD	cd00074	H2A	coord: 12..120 e-value: 2.07067E-57 score: 171.749
IPR009072	Histone-fold	GENE3D	G3DSA:1.10.20.10		coord: 2..125 e-value: 8.5E-51 score: 173.2
IPR009072	Histone-fold	SUPERFAMILY	SSF47113	Histone-fold	coord: 3..100
IPR007125	Histone H2A/H2B/H3	PFAM	PF00125	Histone	coord: 13..92 e-value: 1.6E-17 score: 64.1
IPR032454	Histone H2A, C-terminal domain	PFAM	PF16211	Histone_H2A_C	coord: 93..122 e-value: 1.1E-11 score: 44.3
None	No IPR available	PANTHER	PTHR23430	HISTONE H2A	coord: 4..121
None	No IPR available	PANTHER	PTHR23430:SF47	HISTONE H2A.Z	coord: 4..121