Neurogenic locus Notch protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030526 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: ERICH6 (glutamate rich 6 [Source:HGNC Symbol;Acc:HGNC:28602]) HSP 1 Score: 110.923 bits (276), Expect = 6.595e-25 Identity = 107/399 (26.82%), Postives = 175/399 (43.86%), Query Frame = 1 Query: 793 SNVDQSK-----LFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVII-----NMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNP-ILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPF---QPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKC 1947 SNVD S CC F++L+D+ E TKP K LI I PH +H + K +EK L+R+ +A + + E FS S ++L+ I+YQLS +I K+ + D++ N + + + D G + L+ ++Y +G F+ FP G I+YPSGNLAI V N C++ +D+ NP IL + ++G S H +G++ + + L G + G++ R W W + + PF +P+FL+LNR+IG+RI Q+ I + F ++ +Q I+VG K K+P + +L V + ++ LI I+ R+ +E C Sbjct: 137 SNVDVSSEPKGHASCCIAFQNLIDYIY-----EEQIKTKPP-KAELIAIDPHAAHGSEV--------DRLKAKEKALQRKQEQRMARHFA-------------------IISREQTHFSEDDS------KRLKTISYQLSV------------------DIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKVVRNELL---EKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVN-GFTCIVQEDMPT----NPAILAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNS--ITSSPFVSFKPVFLALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASLIKIR-RLFHKLEGC 467
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: ERICH6 (glutamate rich 6 [Source:HGNC Symbol;Acc:HGNC:28602]) HSP 1 Score: 110.923 bits (276), Expect = 1.224e-24 Identity = 107/399 (26.82%), Postives = 175/399 (43.86%), Query Frame = 1 Query: 793 SNVDQSK-----LFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVII-----NMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNP-ILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPF---QPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKC 1947 SNVD S CC F++L+D+ E TKP K LI I PH +H + K +EK L+R+ +A + + E FS S ++L+ I+YQLS +I K+ + D++ N + + + D G + L+ ++Y +G F+ FP G I+YPSGNLAI V N C++ +D+ NP IL + ++G S H +G++ + + L G + G++ R W W + + PF +P+FL+LNR+IG+RI Q+ I + F ++ +Q I+VG K K+P + +L V + ++ LI I+ R+ +E C Sbjct: 283 SNVDVSSEPKGHASCCIAFQNLIDYIY-----EEQIKTKPP-KAELIAIDPHAAHGSEV--------DRLKAKEKALQRKQEQRMARHFA-------------------IISREQTHFSEDDS------KRLKTISYQLSV------------------DIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKVVRNELL---EKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVN-GFTCIVQEDMPT----NPAILAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNS--ITSSPFVSFKPVFLALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASLIKIR-RLFHKLEGC 613
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: ERICH6B (glutamate rich 6B [Source:HGNC Symbol;Acc:HGNC:26523]) HSP 1 Score: 89.3521 bits (220), Expect = 8.921e-18 Identity = 48/155 (30.97%), Postives = 82/155 (52.90%), Query Frame = 1 Query: 1384 YPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSK--IPE 1842 YPN ++ ++FP G I+YPSGNLA+ I+ ++ D + + I + + +G +F + DI + + G+ +D +K +W+ HVHAPP QP+ L +N +I ++I +Q+ I F +QI +N+G + K IPE Sbjct: 480 YPNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILEDSL-----EGRIRALINNSGNATFYDENSDIWLNLSSNLGYYFPKDKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQIRSQDKIIFCFTYEQKQICLNLGTRYKFVIPE 629
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: ntn3 (netrin 3 [Source:Xenbase;Acc:XB-GENE-960264]) HSP 1 Score: 89.3521 bits (220), Expect = 3.997e-18 Identity = 60/219 (27.40%), Postives = 111/219 (50.68%), Query Frame = 1 Query: 1378 QYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDG----KPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKP-LIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAK 2019 ++Y G F++ FP G A I+YPSGN+A+ + + +I D + IL + ++G + H +G++ + + + G G K R+W W +P+V PF+P+F+SLN+ +GIRI +Q I+++F S+ +Q IN+ + + + Q R+ +V L I + L A K ++ ++ K + P +K P+ +A+ Sbjct: 217 KFYRTGQRFLITFPDGTAQIFYPSGNVAVVAIATNRK-DSVYIIQGDKDV---NADILAVFGSSGKATCYHPNGNVCL--NPVGGQYFDHTGMKLRRWRWKSTDLSEPYV---PFKPVFISLNQQVGIRICSQEQIYISFLSMGKQAKINIWTRHQT--KTQVRINELVNLNKWFIEELILFATKIKILSLLNKLEGYVNFPTNEQWDKLKAPPFLVAQ 424
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: ntn3 (netrin 3 [Source:Xenbase;Acc:XB-GENE-960264]) HSP 1 Score: 85.5001 bits (210), Expect = 3.996e-17 Identity = 48/162 (29.63%), Postives = 88/162 (54.32%), Query Frame = 1 Query: 1378 QYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDG----KPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQ 1851 ++Y G F++ FP G A I+YPSGN+A+ + + +I D + IL + ++G + H +G++ + + + G G K R+W W +P+V PF+P+F+SLN+ +GIRI +Q I+++F S+ +Q IN+ + + +V+ Sbjct: 151 KFYRTGQRFLITFPDGTAQIFYPSGNVAVVAIATNRK-DSVYIIQGDKDV---NADILAVFGSSGKATCYHPNGNVCL--NPVGGQYFDHTGMKLRRWRWKSTDLSEPYV---PFKPVFISLNQQVGIRICSQEQIYISFLSMGKQAKINIWTRHQTKTQVR 303
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Erich6b (glutamate rich 6B [Source:MGI Symbol;Acc:MGI:1922522]) HSP 1 Score: 101.293 bits (251), Expect = 8.200e-22 Identity = 63/172 (36.63%), Postives = 96/172 (55.81%), Query Frame = 1 Query: 1384 YPNGCLFMVIFPTGLASIYYPSGNLAISI-VREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQW-FWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFS-VSRQIHINVGVKSK-IPERVQRRMLAMVKLETD 1887 Y +G F V FP G IYYPSGNLA+ I + AE L I V+ D V + I G+ + +G +F G I + L G+ + G +++ W +W+ HVHAPPF + L LN++I ++I +Q+ + FF+ ++I +N+G K K I E V + ++ V LETD Sbjct: 360 YHSGKSFHVFFPNGTGQIYYPSGNLALLISCKGAEKLTYI-VLEDSV-----RTKIRGLVTNSGHATFYKEDGGIWLSLSKLLGYYFPK-GKQQKAWNWWNLDLHVHAPPFMCITLKLNKYIHVQIRSQDKVIFCFFTPKQKRICLNMGTKFKHINETVHQALMERVVLETD 524
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Erich6 (glutamate rich 6 [Source:MGI Symbol;Acc:MGI:3588212]) HSP 1 Score: 82.0333 bits (201), Expect = 1.143e-15 Identity = 58/186 (31.18%), Postives = 94/186 (50.54%), Query Frame = 1 Query: 1423 GLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNP-ILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGK-PHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI--PERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHP 1968 G + YPSGNLAI I + IC+I +D NP IL + ++G S H +G++ + + L G + G++ R W W P F+P+FL+LNR+IGIRI Q+ + +NF ++ +Q I++G K + PE V A+ L D ++ L+A ++ + K + P Sbjct: 493 GTILLTYPSGNLAI-IRLPNKTDGFICIIQEDTPT----NPTILALFDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRTWNWSSTMPSSSFVSFKPVFLALNRYIGIRILEQDKVSINFLAMGQQATISLGTKVMLHDPEEVP----ALWFLSGDDLL--LLANLIKIRRLFNKLEGCMNFP 667
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|Q5XI56|ERIP6_RAT (Glutamate-rich protein 6 OS=Rattus norvegicus OX=10116 GN=Erich6 PE=2 SV=1) HSP 1 Score: 112.464 bits (280), Expect = 1.578e-24 Identity = 104/391 (26.60%), Postives = 172/391 (43.99%), Query Frame = 1 Query: 820 CCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDG-KPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI--PERVQR-RMLA----MVKLETDKIMKPLIAIKARVNGIIEKCHEALGHP 1968 CC +F++L+D+ R LT S + LI ISPH +H + K +EK ++R+ +A R ++ +P EE+ T+ L+ I+YQLS + + EE+ ++ I N+ T D + G L+ + Y +G F+ FP G I+YPSGNLAI V + IC+I +D + + IL + ++G S H +G++ + + L G + G++ R W W KP F+P+ L+LNR+IGIRI Q+ + ++F ++ +Q I +G K + PE V R L+ ++ KI + ++ VN + K E L P Sbjct: 240 CCLQFQNLLDYITEER------LTTKSPEMELISISPHAAHGSDA--------DRLKAKEKAMQRKQERQMA------------RHFTIIPEQSPVGTEED-------------TKHLKTISYQLSGDYLQN---------VRTEEVDLQ------ITNISITCC--DSWKICGKVMGNELL---EKDYKHGSKFLTSFPDGTIQIFYPSGNLAIIRVPNKTD-GFICIIQEDTA---TSPAILALFDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRTWNWSSTKPTPAFVSFKPVLLALNRYIGIRILEQDKVSIHFLAMGQQATICLGTKVVLQDPEEVPTLRFLSGDDLLLLASLIKIRRLFSKMEGCVNFPVSKAWERLKQP 567
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|Q7L0X2|ERIP6_HUMAN (Glutamate-rich protein 6 OS=Homo sapiens OX=9606 GN=ERICH6 PE=2 SV=1) HSP 1 Score: 110.923 bits (276), Expect = 5.877e-24 Identity = 107/399 (26.82%), Postives = 175/399 (43.86%), Query Frame = 1 Query: 793 SNVDQSK-----LFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVII-----NMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNP-ILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPF---QPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKC 1947 SNVD S CC F++L+D+ E TKP K LI I PH +H + K +EK L+R+ +A + + E FS S ++L+ I+YQLS +I K+ + D++ N + + + D G + L+ ++Y +G F+ FP G I+YPSGNLAI V N C++ +D+ NP IL + ++G S H +G++ + + L G + G++ R W W + + PF +P+FL+LNR+IG+RI Q+ I + F ++ +Q I+VG K K+P + +L V + ++ LI I+ R+ +E C Sbjct: 283 SNVDVSSEPKGHASCCIAFQNLIDYIY-----EEQIKTKPP-KAELIAIDPHAAHGSEV--------DRLKAKEKALQRKQEQRMARHFA-------------------IISREQTHFSEDDS------KRLKTISYQLSV------------------DIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKVVRNELL---EKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVN-GFTCIVQEDMPT----NPAILAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNS--ITSSPFVSFKPVFLALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASLIKIR-RLFHKLEGC 613
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|Q5W0A0|ERI6B_HUMAN (Glutamate-rich protein 6B OS=Homo sapiens OX=9606 GN=ERICH6B PE=2 SV=1) HSP 1 Score: 89.3521 bits (220), Expect = 4.284e-17 Identity = 48/155 (30.97%), Postives = 82/155 (52.90%), Query Frame = 1 Query: 1384 YPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSK--IPE 1842 YPN ++ ++FP G I+YPSGNLA+ I+ ++ D + + I + + +G +F + DI + + G+ +D +K +W+ HVHAPP QP+ L +N +I ++I +Q+ I F +QI +N+G + K IPE Sbjct: 480 YPNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILEDSL-----EGRIRALINNSGNATFYDENSDIWLNLSSNLGYYFPKDKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQIRSQDKIIFCFTYEQKQICLNLGTRYKFVIPE 629
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|D3Z6S9|ERIP6_MOUSE (Glutamate-rich protein 6 OS=Mus musculus OX=10090 GN=Erich6 PE=3 SV=1) HSP 1 Score: 82.0333 bits (201), Expect = 7.999e-15 Identity = 58/186 (31.18%), Postives = 94/186 (50.54%), Query Frame = 1 Query: 1423 GLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNP-ILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGK-PHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI--PERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHP 1968 G + YPSGNLAI I + IC+I +D NP IL + ++G S H +G++ + + L G + G++ R W W P F+P+FL+LNR+IGIRI Q+ + +NF ++ +Q I++G K + PE V A+ L D ++ L+A ++ + K + P Sbjct: 493 GTILLTYPSGNLAI-IRLPNKTDGFICIIQEDTPT----NPTILALFDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRTWNWSSTMPSSSFVSFKPVFLALNRYIGIRILEQDKVSINFLAMGQQATISLGTKVMLHDPEEVP----ALWFLSGDDLL--LLANLIKIRRLFNKLEGCMNFP 667
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A267ETE8 (FAM194 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030731g3 PE=4 SV=1) HSP 1 Score: 203.756 bits (517), Expect = 1.001e-52 Identity = 151/506 (29.84%), Postives = 249/506 (49.21%), Query Frame = 1 Query: 403 QSSASSESLPVYPSRKIDDEFGIXXXXXXXXXXXXXXXXXXXTLINEDSNKKMPISNDEEIEN--------AIQKNIIFDAGLPTFLKASKELGNP--DIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIA------HRQNESNSLTKPSSKQNLIDISPH---KSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLP--MICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDG-------KPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI 1836 +S A ++P YP ++DDEFG+ L D + +++ +L+N S+K + + E A ++ G P L+ +E P + P +S D A +M G D C+FC +P+ +PS +Q + +Q L+CC EFR L++FA+ H+Q ++ S LID++PH S E+ + E + R KLL+++ A R S E+ M RQ+R INY LSS + +++GWT+R P+ + +S E + +MD I D+ +G++ + + + ++YPNG F+ +F +++YPSG LAI I R A+ P ++ ++ DD ++ +LG+ G G+ G IRI YD NG ++ + GSKKR W W PH+HAPPFQP+ L+LN+ +G+R++A++ I+++F + SR INVG + KI Sbjct: 111 RSRAGGLTIPAYPEPRVDDEFGVLLVQDDDSDLSDTNVKGD-SLVNSGSSKNAGLETVDTAEAVGVADEEPAADNGLLPSVGPPQILQYLRESQIPVEEAFPGLSLD-LGAVSMREG--DSCDFCGRPIQALPSREDQASRSPEQ--LYCCAEFRKLLEFALQYQTRLLHQQQQTES--------GLIDVAPHPHFGSRGKKSAQERERMREEAEKRRKLLQQERQRRAAEAAQATAQARKREQVS---------------------VEADMGRQMRTINYSLSSMRCLEEGWTLRAPSPLGDGVS---EWQIYDFDMDE---ITDLAAGLGITPRGTPTDLLEKFYPNGKKFVTMFADRTGNVFYPSGRLAILISRPADR-PNNLLHIVLDDKPPGRAR--LLGVFDNIGRGTAYFRDGGIRINYDRFNGLDLDQQGSKKRHWHWHSTGQPAAQAPHIHAPPFQPISLALNKTVGLRLAARDSIYLSFVTASRSCKINVGARIKI 572
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A267F7T6 (FAM194 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030731g1 PE=4 SV=1) HSP 1 Score: 202.986 bits (515), Expect = 2.039e-52 Identity = 151/506 (29.84%), Postives = 249/506 (49.21%), Query Frame = 1 Query: 403 QSSASSESLPVYPSRKIDDEFGIXXXXXXXXXXXXXXXXXXXTLINEDSNKKMPISNDEEIEN--------AIQKNIIFDAGLPTFLKASKELGNP--DIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIA------HRQNESNSLTKPSSKQNLIDISPH---KSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLP--MICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDG-------KPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI 1836 +S A ++P YP ++DDEFG+ L D + +++ +L+N S+K + + E A ++ G P L+ +E P + P +S D A +M G D C+FC +P+ +PS +Q + +Q L+CC EFR L++FA+ H+Q ++ S LID++PH S E+ + E + R KLL+++ A R S E+ M RQ+R INY LSS + +++GWT+R P+ + +S E + +MD I D+ +G++ + + + ++YPNG F+ +F +++YPSG LAI I R A+ P ++ ++ DD ++ +LG+ G G+ G IRI YD NG ++ + GSKKR W W PH+HAPPFQP+ L+LN+ +G+R++A++ I+++F + SR INVG + KI Sbjct: 111 RSRAGGLTIPAYPEPRVDDEFGVLLVQDDDSDLSDTNVKGD-SLVNSGSSKNAGLETVDTAEAVGVADEEPAADNGLLPSVGPPQILQYLRESQIPVEEAFPGLSLD-LGAVSMREG--DSCDFCGRPIQALPSREDQASRSPEQ--LYCCAEFRKLLEFALQYQTRLLHQQQQTES--------GLIDVAPHPHFGSRGKKSAQERERMREEAEKRRKLLQQERQRRAAEAAQATAQARKREQVS---------------------VEADMGRQMRTINYSLSSMRCLEEGWTLRAPSPLGDGVS---EWQIYDFDMDE---ITDLAAGLGITPRGTPTDLLEKFYPNGKKFVTMFADRTGNVFYPSGRLAILISRPADR-PNNLLHIVLDDKPPDRAR--LLGVFDNIGRGTAYFRDGGIRINYDRFNGLDLDQQGSKKRHWHWHSTGQPAAQAPHIHAPPFQPISLALNKTVGLRLAARDSIYLSFVTASRSCKINVGARIKI 572
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: V4BBD1 (FAM194 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_229951 PE=4 SV=1) HSP 1 Score: 190.66 bits (483), Expect = 6.683e-48 Identity = 118/382 (30.89%), Postives = 203/382 (53.14%), Query Frame = 1 Query: 736 CEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLER--QNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFS---IRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIIN--MDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFW-DGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI--PERVQ 1851 CEFC + P P++ +Q + +Q L+CC ++R+ V FA + + K + LIDI PH + + K ++ +++R++ +E+ Q A + + + G + +E+ ++ F S + ++ RQ++ INYQLSS K +++GWT R P ++ M DV I +D+T + S + + ++ Y NG F++IFP G S++YPSG LA+SI + + I V+HD+ S + I+G+ NG G H +G++R+ +D L+G E+ + G+KK++W W D + HVHAPPFQP+ + LNR IG+R+ +Q I V F + +R NVG + ++ PE ++ Sbjct: 231 CEFCELDIKPFPTIEQQQELPPEQ--LYCCDQYREFVQFATSTAFELEEEMQK---TKKLIDIKPHGHFGSKKARKAAKERAVQRMRDREMEKRKQEATGMNSYFAGASPSGEFGSATEVGGGRAGAGRNQGFKGNGPAPLSYKDMVARQMKTINYQLSSQKCLEEGWTKRAPTPQEDDGDMI----DVFIPEPLDFT---------LANSAKIRERELIQKNYENGKKFLMIFPDGTGSVFYPSGYLAVSICK-MDAGQFIYVVHDN----SSDSRIMGVFEPNGHGCCYHNNGNVRLYFDQLDGIELDKYGAKKKKWSWKDQETHVHAPPFQPICVGLNRSIGLRVMSQEHITVTFMAKNRSCRFNVGARLRLMKPENIK 589
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A267F005 (FAM194 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030731g2 PE=4 SV=1) HSP 1 Score: 182.956 bits (463), Expect = 4.749e-47 Identity = 122/387 (31.52%), Postives = 198/387 (51.16%), Query Frame = 1 Query: 730 DVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIA------HRQNESNSLTKPSSKQNLIDIS--PH-KSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLP--MICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGK-------PHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI 1836 D C+FC +P+ +PS +Q + +Q L+CC EFR L++FA+ H+Q ++ S LID++ PH S E+ + E + R KLL+++ A R S E+ M RQ+R INY LSS + +++GWT+R P+ + +S E + +MD I D+ +G++ + + + ++YPNG F+ +F +++YPSG LAI I R A+ P ++ ++ DD ++ +LG+ G G+ G IRI YD NG ++ + GSKKR W W PH+HAPPFQP+ L+LN+ +G+R++A++ I+++F + SR INVG + KI Sbjct: 5 DSCDFCGRPIQALPSREDQASRSPEQ--LYCCAEFRKLLEFALQYQTRLLHQQQQTES--------GLIDVAPHPHFGSRGKKSAQERERMREEAEKRRKLLQQERQRRAAEAAQATAQARKREQVS---------------------VEADMGRQMRTINYSLSSMRCLEEGWTLRAPSPLGDGVS---EWQIYDFDMDE---ITDLAAGLGITPRGTPTDLLEKFYPNGKKFVTMFADRTGNVFYPSGRLAILISRPADR-PNNLLHIVLDDKPPGRAR--LLGVFDNIGRGTAYFRDGGIRINYDRFNGLDLDQQGSKKRHWHWHSTGQPAAQAPHIHAPPFQPISLALNKTVGLRLAARDSIYLSFVTASRSCKINVGARIKI 351
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A1S3JRJ2 (glutamate-rich protein 6-like OS=Lingula unguis OX=7574 GN=LOC106175238 PE=4 SV=1) HSP 1 Score: 182.185 bits (461), Expect = 1.123e-44 Identity = 126/419 (30.07%), Postives = 201/419 (47.97%), Query Frame = 1 Query: 733 VCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKD----VIINMDYTSLIPDIYGQIGLSDQCSLIGVS-RQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNP-ILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFW-DGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHP 1968 VCEFC+K + P PS+ EQ DQ L+CC+E+R V FA+ N + IDI PH + + K ++ ++RE+ L R A Q + + + FF+ R ++ INYQLSS + +D+GWT+RPP+ + EE KD + ++D+T + + GL + GV+ +YY +G LF+V+FP G +YYPSGNLAI I ++ D ++ P +LG+ NG +G +R+ D + G E+ +G+KK++W W D HVHAPPFQP+ +LNR + +R Q+ I + F S + NVG K K+ V + + ++E +++ L K +V +++K + P Sbjct: 334 VCEFCQKTIKPFPSMEEQQTKPPDQ--LYCCEEYRQFVHFALF------NPMETEHKVDEKIDIKPHGPFGSKQARRAAKERAVLRMRERELARAQQVAAAQQAA------------------AGGGGVSNFFTF--------ARAMKTINYQLSSQRCLDEGWTVRPPS------PLWEEAKDPDVFSVEDVDFT-----MNAKEGLGWELRKRGVTLEKYYEDGSLFLVLFPDGTGHVYYPSGNLAIGISSTTPGKFTYVILED-----AAEEPQVLGVFEPNGHAGCYFHNGKLRLCLDQMGGIELDINGAKKKKWNWKDVTTHVHAPPFQPICFALNRCLSLRFLDQDNISLLFQSHKQSCKFNVGAKLKL---VNPEYIPVKEIEENEVF--LSECKTKVEFLLDKVANLMKFP 697
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: ENSAMXT00000019601.2 (glutamate-rich protein 6-like [Source:NCBI gene;Acc:107197653]) HSP 1 Score: 100.138 bits (248), Expect = 9.209e-22 Identity = 78/290 (26.90%), Postives = 140/290 (48.28%), Query Frame = 1 Query: 985 RKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVE--EENEFFSIRQSTESVMTR----QLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKI 1836 R + E ER L A +S E + E S +S ++ E F+ Q+ S+ T + I++QLS C +D+ + + ++ S +EE +V D + P +G L + I +++Y NG F+ F G A ++YPSGNLAI ++ + +CV+ D+++ S P+ + ++G + H +G + + D G + G++ R+W W + P +P+FLSLN+ +G+R+ + IFV+F ++ +Q +VG KI Sbjct: 111 RFVLELCEERPRGTLTAGDLSIGFEEQLKLGAGEWDSEESRLQQMEMERFYREAQTRPSMSTDTSLFHTKTISFQLSGCDPVDERLNL-----AVKKESSEEEKPEVWEWNDPSGSEPAGFGLNHLQEGARFI---QKFYSNGNKFLTGFSDGSAQVFYPSGNLAIIVLTNKKE--RVCVVRDNIT---SHCPVRALFQSSGRATCYHGNGRVWLNMDLWGGQSLDEAGARTRKWSWSDRAQT-PTPLRPIFLSLNKSVGVRVLGRQYIFVSFLALGQQAKFSVGSCVKI 386
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO33633 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRP5]) HSP 1 Score: 153.295 bits (386), Expect = 9.266e-39 Identity = 125/486 (25.72%), Postives = 220/486 (45.27%), Query Frame = 1 Query: 598 QKNIIFDAGLPTFLKASKE-----LGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNP-ILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFW-DGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERK 2034 ++ +I G P L+ KE L N ++ FL ++ G C FC++ ++P P++ E+I+S + +LFCC ++ + F + HR +ES+ + LIDI PH + T K ++ + RE+ +ERQ AA P Y+ +TRQ++ INY L+S K M++GWT++P + + E+ + +N + + + L ++Y +G F+++ P G YYPSGN+A+ ++ E ++++D F+ ++ L G G+ +G +R++ D G + G++K++W W + K HVHAPPFQP+ SL + + IR +QN I + + NVG K K ++ ++ D+ L +K +N ++++ AL PN +K PL P L K R+ Sbjct: 357 EETLIPSIGPPAILQYIKESQHPPLTNEELEERDIGGEFLKKSVFSG---PCMFCKEEVLPFPTI-EEIES-LSPEQLFCCPQYERFIKFELTHRGDESHI------RDELIDIKPHPPYGTKAARRAAKERAAERAREREMERQKAA-----------GNPTNFYA-------------------------LTRQMKTINYSLASTKCMEEGWTVKPRSPTPSIDGQGEDQFVIEVN------------PLQMQKRAFL----ERFYEDGQRFLLVLPDGTGCCYYPSGNIAV-LITSTERGKFNYLVYEDSDEFDIQHTGTLASFDPTGHGTCYFRNGAVRLVVDPFGGVLLDSSGTRKKKWLWHNHKTHVHAPPFQPITFSLTKQLAIRCLSQNKIVITYTHGKHTAKFNVGSKLKAVRNLK------PPIDRDEHELHLAEVKQFINILLDRTQNALRLPNYPRLDKIPL-PQRLQKTMRRE 771
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000035155.1 (SMESG000035155.1) HSP 1 Score: 1288.48 bits (3333), Expect = 0.000e+0 Identity = 655/662 (98.94%), Postives = 659/662 (99.55%), Query Frame = 1 Query: 73 MNELILTSIKEESAASYNINEFSPDNLTSPILPLQQVIEKAVQTDSDWLDQIKREIFDAITHETSIKEQIPQKPKSKAGTIRSQMTKTSVIKSKAKDDQALAEDYERENCQSSASSESLPVYPSRKIDDEFGIXXXXXXXXXXXXXXXXXXXTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV 2058 MNELILTSIKEESAASYNINEFSPDNLTSPIL LQQVIEKAVQTDSDWLDQIKREIFDAITHET+IKEQIPQKPKSKAGTIRSQMTKTSVIKSKAK DQALAEDYER+NC+SSASSESLPVYPSRKIDDEFGIELYDSSDDEDDSIDL KLSTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTLEELAEEKAKSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMIC+IHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV Sbjct: 1 MNELILTSIKEESAASYNINEFSPDNLTSPILSLQQVIEKAVQTDSDWLDQIKREIFDAITHETNIKEQIPQKPKSKAGTIRSQMTKTSVIKSKAKADQALAEDYERDNCESSASSESLPVYPSRKIDDEFGIELYDSSDDEDDSIDLAKLSTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTLEELAEEKAKSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICIIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV 662
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000035155.1 (SMESG000035155.1) HSP 1 Score: 1249.19 bits (3231), Expect = 0.000e+0 Identity = 641/662 (96.83%), Postives = 645/662 (97.43%), Query Frame = 1 Query: 73 MNELILTSIKEESAASYNINEFSPDNLTSPILPLQQVIEKAVQTDSDWLDQIKREIFDAITHETSIKEQIPQKPKSKAGTIRSQMTKTSVIKSKAKDDQALAEDYERENCQSSASSESLPVYPSRKIDDEFGIXXXXXXXXXXXXXXXXXXXTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV 2058 MNELILTSIKEESAASYNINEFSPDNLTSPIL LQQVIEKAVQTDSDWLDQIKREIFDAITHET+IKEQIPQKPKSKAGTIRSQMTKTSVIKSKAK DQALAEDYER+NC+SSASSESLPVYPSRKIDDEFGIELYDSSDDEDDSIDL KLSTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTLEELAEEKAKSERKIREKLLERQNAALLAAQMSRMK KSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMIC+IHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV Sbjct: 1 MNELILTSIKEESAASYNINEFSPDNLTSPILSLQQVIEKAVQTDSDWLDQIKREIFDAITHETNIKEQIPQKPKSKAGTIRSQMTKTSVIKSKAKADQALAEDYERDNCESSASSESLPVYPSRKIDDEFGIELYDSSDDEDDSIDLAKLSTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTLEELAEEKAKSERKIREKLLERQNAALLAAQMSRMK-------------TKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICIIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV 649
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000035155.1 (SMESG000035155.1) HSP 1 Score: 1236.48 bits (3198), Expect = 0.000e+0 Identity = 635/662 (95.92%), Postives = 639/662 (96.53%), Query Frame = 1 Query: 73 MNELILTSIKEESAASYNINEFSPDNLTSPILPLQQVIEKAVQTDSDWLDQIKREIFDAITHETSIKEQIPQKPKSKAGTIRSQMTKTSVIKSKAKDDQALAEDYERENCQSSASSESLPVYPSRKIDDEFGIXXXXXXXXXXXXXXXXXXXTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTXXXXXXXXXXSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPSAKSTVEEENEFFSIRQSTESVMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICVIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV 2058 MNELILTSIKEESAASYNINEFSPDNLTSPIL LQQVIEKAVQTDSDWLDQIKREIFDAITHET+IKEQIPQKPKSKAGTIRSQMTKTSVIKSKAK DQALAEDYER+NC+SSASSESLPVYPSRKIDDEFGIELYDSSDDEDDSIDL KLSTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTLEELAEEKAKSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPS VMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMIC+IHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV Sbjct: 1 MNELILTSIKEESAASYNINEFSPDNLTSPILSLQQVIEKAVQTDSDWLDQIKREIFDAITHETNIKEQIPQKPKSKAGTIRSQMTKTSVIKSKAKADQALAEDYERDNCESSASSESLPVYPSRKIDDEFGIELYDSSDDEDDSIDLAKLSTLINEDSNKKMPISNDEEIENAIQKNIIFDAGLPTFLKASKELGNPDIAPPMSADAFLASAMLPGREDVCEFCRKPLIPIPSVHEQIDSNVDQSKLFCCQEFRDLVDFAIAHRQNESNSLTKPSSKQNLIDISPHKSHKTLEELAEEKAKSERKIREKLLERQNAALLAAQMSRMKIEGPRRAYSEMPS--------------------VMTRQLRVINYQLSSCKFMDDGWTIRPPAISNEEISMKEELKDVIINMDYTSLIPDIYGQIGLSDQCSLIGVSRQYYPNGCLFMVIFPTGLASIYYPSGNLAISIVREAENLPMICIIHDDVSIFESKNPILGIASTNGFGSFSHTSGDIRILYDTLNGFEIHRDGSKKRQWFWDGKPHVHAPPFQPLFLSLNRFIGIRISAQNGIFVNFFSVSRQIHINVGVKSKIPERVQRRMLAMVKLETDKIMKPLIAIKARVNGIIEKCHEALGHPNLLLENKWPLKPYALAKITERKNTLSLSMV 642 The following BLAST results are available for this feature:
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 3
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 2
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030526 ID=SMED30030526|Name=Neurogenic locus Notch protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2148bpback to top protein sequence of SMED30030526-orf-1 >SMED30030526-orf-1 ID=SMED30030526-orf-1|Name=SMED30030526-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=663bp MNELILTSIKEESAASYNINEFSPDNLTSPILPLQQVIEKAVQTDSDWLDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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