peptidyl prolyl cis trans isomerase FKBP-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030477 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 15
Homology
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Human
Match: FKBP4 (FKBP prolyl isomerase 4 [Source:HGNC Symbol;Acc:HGNC:3720]) HSP 1 Score: 349.362 bits (895), Expect = 8.412e-116 Identity = 181/402 (45.02%), Postives = 266/402 (66.17%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGK 1302
DISP D+GVLK I EG G MP+ G +VFVHY G DG KFDSS DR+DKFSF LG+G+VIKAWDI +ATMK EVC + CKP YAYG + IP N+TL FE+ELF++KG+D++ +DG II+ I +G GY P E V+++++G + + FD+R++ FEIG+ + L G+E A ++M+K E SI + +YAFG++GK ++ IPPNA + YE+H+K FEK KES+ ++ ++EKL+ + K R T + G A Y++ +S++EY+S F++EE L L+ LNLA+C+LK IE C+KALEL+ +EK L+R+G+A + +D+E A++ F K+L P+N A+ Q+ +C +I+ L EKKLY +MF ++ +
Sbjct: 24 DISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLL----DGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMN-SEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Human
Match: FKBP5 (FKBP prolyl isomerase 5 [Source:HGNC Symbol;Acc:HGNC:3721]) HSP 1 Score: 317.005 bits (811), Expect = 3.252e-103 Identity = 179/408 (43.87%), Postives = 255/408 (62.50%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKAT-GSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTAD 1317
EDI+ D+GVLK + G GE P+ G KV+VHY G S +G+KFDSS DR + F F+LG+GQVIKAWDIGVATMKK E+C L+CKP YAYG + IP+N+TL FEIEL D+KG+D+ +DG II+ +G GY +P E V+I ++G FD RDV F +G+ + GI+ A +KM++ E+ I + Y FG GK ++ I PNA + YE+ +K FEK KES+ +D TKEKL+ A K + T + G A Y + +S++E + +++E + LL+ LNLA+CYLK + K +E CDKAL L+ A+EK LYR+G+A ++ +++E AK F K+L NP N A+ QI +C K KEH ++++Y +MF K + D +
Sbjct: 23 EDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS----NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMD-TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKE 423
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Human
Match: FKBP5 (FKBP prolyl isomerase 5 [Source:HGNC Symbol;Acc:HGNC:3721]) HSP 1 Score: 317.005 bits (811), Expect = 3.252e-103 Identity = 179/408 (43.87%), Postives = 255/408 (62.50%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKAT-GSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTAD 1317
EDI+ D+GVLK + G GE P+ G KV+VHY G S +G+KFDSS DR + F F+LG+GQVIKAWDIGVATMKK E+C L+CKP YAYG + IP+N+TL FEIEL D+KG+D+ +DG II+ +G GY +P E V+I ++G FD RDV F +G+ + GI+ A +KM++ E+ I + Y FG GK ++ I PNA + YE+ +K FEK KES+ +D TKEKL+ A K + T + G A Y + +S++E + +++E + LL+ LNLA+CYLK + K +E CDKAL L+ A+EK LYR+G+A ++ +++E AK F K+L NP N A+ QI +C K KEH ++++Y +MF K + D +
Sbjct: 23 EDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS----NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMD-TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKE 423
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Human
Match: FKBP5 (FKBP prolyl isomerase 5 [Source:HGNC Symbol;Acc:HGNC:3721]) HSP 1 Score: 317.005 bits (811), Expect = 3.252e-103 Identity = 179/408 (43.87%), Postives = 255/408 (62.50%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKAT-GSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTAD 1317
EDI+ D+GVLK + G GE P+ G KV+VHY G S +G+KFDSS DR + F F+LG+GQVIKAWDIGVATMKK E+C L+CKP YAYG + IP+N+TL FEIEL D+KG+D+ +DG II+ +G GY +P E V+I ++G FD RDV F +G+ + GI+ A +KM++ E+ I + Y FG GK ++ I PNA + YE+ +K FEK KES+ +D TKEKL+ A K + T + G A Y + +S++E + +++E + LL+ LNLA+CYLK + K +E CDKAL L+ A+EK LYR+G+A ++ +++E AK F K+L NP N A+ QI +C K KEH ++++Y +MF K + D +
Sbjct: 23 EDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS----NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMD-TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKE 423
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Human
Match: FKBP5 (FKBP prolyl isomerase 5 [Source:HGNC Symbol;Acc:HGNC:3721]) HSP 1 Score: 181.03 bits (458), Expect = 3.715e-53 Identity = 98/201 (48.76%), Postives = 131/201 (65.17%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKAT-GSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIF 696
EDI+ D+GVLK + G GE P+ G KV+VHY G S +G+KFDSS DR + F F+LG+GQVIKAWDIGVATMKK E+C L+CKP YAYG + IP+N+TL FEIEL D+KG+D+ +DG II+ +G GY +P E V+I ++G FD RDV F +G+ + GI+ A +KM++ E+ I
Sbjct: 23 EDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS----NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL 217
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Celegans
Match: fkb-6 (Peptidylprolyl isomerase [Source:UniProtKB/TrEMBL;Acc:O45418]) HSP 1 Score: 288.886 bits (738), Expect = 5.455e-93 Identity = 167/401 (41.65%), Postives = 237/401 (59.10%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISAN-YAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKV 1296
DI+P D GVLK I EG G P G V VHYVGT ++G KFDSSRDR D+FSF LG G VIK WD+GVATM K EV E + Y YGD + IP +TL FE+ELF+W +DISP +DG+I++TI+ +G P + V GT+ F R+V+F IG+ + GL +G+E A ++ + EKS EI + Y +GN + NIP NAT+ + I +K+FEKV ++ + T +EKLD A + K R T LQ GN+ A Y+R+ +EY+ + E+ R +L LNL+L K ++ ++ I+ CDK LE P + KALYRK AL+ ++ +A +F KI+ P N A QI +C I+E +KK ++++F+K+
Sbjct: 7 DITPKKDGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTL----ENGTKFDSSRDRGDQFSFNLGRGNVIKGWDLGVATMTKGEVAEFTIRSDYGYGDAGSPPKIPGGATLIFEVELFEWSAEDISPDRDGTILRTIIVEGSKNSFPNDTSKVLAHCVGTYQGTEFYNREVNFHIGEGSEEGLPEGVERALRRFQLGEKSKIEIRGHKYTYGNSPPAGSNIPVNATLEFTIFLKEFEKVPATWEM-TAEEKLDAAKQAKDRGTMYLQKGNLKLAYNKYKRAEEVLEYEKSTDPEKMAERETILNGAYLNLSLVCSKQNEQLECIKWCDKVLETKPGNVKALYRKATALLTMNEVRDAMKLFEKIVEVEPENKAAAQQIIVCRNTIREQNERDKKRFKNLFAKI 402 HSP 2 Score: 51.6026 bits (122), Expect = 7.987e-7 Identity = 40/125 (32.00%), Postives = 62/125 (49.60%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEG----------QVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIEL 441
EDISPD D +L+ II EG + P + +KV H VGT+ G E +RE +F +GEG + ++ + +G +K+++ K +Y A +IP N+TL+F I L
Sbjct: 123 EDISPDRDGTILRTIIVEGSKNSFPNDTSKVLAHCVGTYQGTE--------FYNRE--VNFHIGEGSEEGLPEGVERALRRFQLG----EKSKIEIRGHKYTYGNSPPAGSNIPVNATLEFTIFL 233
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Celegans
Match: fkb-6 (Peptidylprolyl isomerase [Source:UniProtKB/TrEMBL;Acc:O45418]) HSP 1 Score: 288.886 bits (738), Expect = 5.455e-93 Identity = 167/401 (41.65%), Postives = 237/401 (59.10%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISAN-YAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKV 1296
DI+P D GVLK I EG G P G V VHYVGT ++G KFDSSRDR D+FSF LG G VIK WD+GVATM K EV E + Y YGD + IP +TL FE+ELF+W +DISP +DG+I++TI+ +G P + V GT+ F R+V+F IG+ + GL +G+E A ++ + EKS EI + Y +GN + NIP NAT+ + I +K+FEKV ++ + T +EKLD A + K R T LQ GN+ A Y+R+ +EY+ + E+ R +L LNL+L K ++ ++ I+ CDK LE P + KALYRK AL+ ++ +A +F KI+ P N A QI +C I+E +KK ++++F+K+
Sbjct: 7 DITPKKDGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTL----ENGTKFDSSRDRGDQFSFNLGRGNVIKGWDLGVATMTKGEVAEFTIRSDYGYGDAGSPPKIPGGATLIFEVELFEWSAEDISPDRDGTILRTIIVEGSKNSFPNDTSKVLAHCVGTYQGTEFYNREVNFHIGEGSEEGLPEGVERALRRFQLGEKSKIEIRGHKYTYGNSPPAGSNIPVNATLEFTIFLKEFEKVPATWEM-TAEEKLDAAKQAKDRGTMYLQKGNLKLAYNKYKRAEEVLEYEKSTDPEKMAERETILNGAYLNLSLVCSKQNEQLECIKWCDKVLETKPGNVKALYRKATALLTMNEVRDAMKLFEKIVEVEPENKAAAQQIIVCRNTIREQNERDKKRFKNLFAKI 402 HSP 2 Score: 51.6026 bits (122), Expect = 7.987e-7 Identity = 40/125 (32.00%), Postives = 62/125 (49.60%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEG----------QVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIEL 441
EDISPD D +L+ II EG + P + +KV H VGT+ G E +RE +F +GEG + ++ + +G +K+++ K +Y A +IP N+TL+F I L
Sbjct: 123 EDISPDRDGTILRTIIVEGSKNSFPNDTSKVLAHCVGTYQGTE--------FYNRE--VNFHIGEGSEEGLPEGVERALRRFQLG----EKSKIEIRGHKYTYGNSPPAGSNIPVNATLEFTIFL 233
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Celegans
Match: fkb-2 (Peptidylprolyl isomerase [Source:UniProtKB/TrEMBL;Acc:Q9U2Q8]) HSP 1 Score: 84.3445 bits (207), Expect = 1.265e-19 Identity = 48/108 (44.44%), Postives = 61/108 (56.48%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKAT-GSIPANSTLKFEIELF 444
GV ++I+ EG P NG V HYV T ++G+K DSSRDR F F +G+G+VIK WD GVA M E +L YG + IPAN+TL FE+EL
Sbjct: 2 GVDRQILVEGDNVTKPKNGQTVTCHYVLTL----ENGKKIDSSRDRGTPFKFKIGKGEVIKGWDQGVAQMSVGEKSKLTISADLGYGPRGVPPQIPANATLVFEVELL 105
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Celegans
Match: fkb-1 (Peptidylprolyl isomerase [Source:UniProtKB/TrEMBL;Acc:Q20107]) HSP 1 Score: 80.1073 bits (196), Expect = 7.708e-18 Identity = 41/90 (45.56%), Postives = 54/90 (60.00%), Query Frame = 1
Query: 178 GAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDK-ATGSIPANSTLKFEIELF 444
G ++ +HY GT DG +FDSSR R ++F+FTLG+G VIK WD G+ M E L P YG++ A IP NS LKF++EL
Sbjct: 45 GDQLHMHYTGTLL----DGTEFDSSRTRNEEFTFTLGQGNVIKGWDQGLLNMCVGERRILTIPPHLGYGERGAPPKIPGNSVLKFDVELM 130
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Celegans
Match: fkb-1 (Peptidylprolyl isomerase [Source:UniProtKB/TrEMBL;Acc:Q20107]) HSP 1 Score: 80.1073 bits (196), Expect = 7.708e-18 Identity = 41/90 (45.56%), Postives = 54/90 (60.00%), Query Frame = 1
Query: 178 GAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDK-ATGSIPANSTLKFEIELF 444
G ++ +HY GT DG +FDSSR R ++F+FTLG+G VIK WD G+ M E L P YG++ A IP NS LKF++EL
Sbjct: 45 GDQLHMHYTGTLL----DGTEFDSSRTRNEEFTFTLGQGNVIKGWDQGLLNMCVGERRILTIPPHLGYGERGAPPKIPGNSVLKFDVELM 130
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Fly
Match: Fkbp59 (gene:FBgn0029174 transcript:FBtr0079872) HSP 1 Score: 280.026 bits (715), Expect = 1.786e-89 Identity = 166/405 (40.99%), Postives = 239/405 (59.01%), Query Frame = 1
Query: 103 ISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS---IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGD 1308
I D GVLK+I+ EG G P +G V +HY G DG +FDSS R + F F+LG+G VIKA+D+GVATMK E C L C P+YAYG A GS IP ++TL FE+E+ WKG+D+SP +DGSI +TI+ +P + VK I G+F+ F++RDV+F+ G+ + G+I G+EIA +KM E S +I A YAFG G E+ IPPNATV Y + + D K E + L + +E+L A +K + T + N A K+Y + + + N+E K + ++ N+ALC+ KS+D + +EC++ L L+ + KALYR+GQ + ++ E+A F K++ P N A NQ+ IC K+KE N EKKLY +MF+K+ D
Sbjct: 7 IDLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLV----DGTEFDSSLSRNEPFEFSLGKGNVIKAFDMGVATMKLGERCFLTCAPNYAYG--AAGSPPAIPPDATLIFELEMLGWKGEDLSPNQDGSIDRTILEASDKKRTPSDGAFVKAHISGSFEGRVFEDRDVEFDYGEGKAIGIIDGVEIALEKMNVGETSRIKIQAKYAFGAKGNEEFKIPPNATVEYTVKLVDCGKGLEEWKL-SDEERLAEAKVYKEKGTNYFKKENWALAIKMYTKCKNILPTTVHTNEEVK----KIKVATHSNIALCHQKSNDHFEAKQECNEVLALDKNNVKALYRRGQCNLTINELEDALEDFQKVIQLEPGNKAAANQVIICKQKLKESKNKEKKLYANMFTKLAAND 400 HSP 2 Score: 52.373 bits (124), Expect = 5.006e-7 Identity = 36/119 (30.25%), Postives = 56/119 (47.06%), Query Frame = 1
Query: 451 KGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTF-DNVSFD---ERDVDFEIGDAASFG---LIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHM 786
+G I DG +++ I+ +G G E+P V + G D FD R+ FE S G +I+ ++ MK E+ + NYA+G G S IPP+AT+ +E+ M
Sbjct: 3 EGNKIDLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEFDSSLSRNEPFEF----SLGKGNVIKAFDMGVATMKLGERCFLTCAPNYAYGAAG-SPPAIPPDATLIFELEM 116
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Fly
Match: Fkbp59 (gene:FBgn0029174 transcript:FBtr0342837) HSP 1 Score: 280.026 bits (715), Expect = 1.786e-89 Identity = 166/405 (40.99%), Postives = 239/405 (59.01%), Query Frame = 1
Query: 103 ISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS---IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGD 1308
I D GVLK+I+ EG G P +G V +HY G DG +FDSS R + F F+LG+G VIKA+D+GVATMK E C L C P+YAYG A GS IP ++TL FE+E+ WKG+D+SP +DGSI +TI+ +P + VK I G+F+ F++RDV+F+ G+ + G+I G+EIA +KM E S +I A YAFG G E+ IPPNATV Y + + D K E + L + +E+L A +K + T + N A K+Y + + + N+E K + ++ N+ALC+ KS+D + +EC++ L L+ + KALYR+GQ + ++ E+A F K++ P N A NQ+ IC K+KE N EKKLY +MF+K+ D
Sbjct: 7 IDLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLV----DGTEFDSSLSRNEPFEFSLGKGNVIKAFDMGVATMKLGERCFLTCAPNYAYG--AAGSPPAIPPDATLIFELEMLGWKGEDLSPNQDGSIDRTILEASDKKRTPSDGAFVKAHISGSFEGRVFEDRDVEFDYGEGKAIGIIDGVEIALEKMNVGETSRIKIQAKYAFGAKGNEEFKIPPNATVEYTVKLVDCGKGLEEWKL-SDEERLAEAKVYKEKGTNYFKKENWALAIKMYTKCKNILPTTVHTNEEVK----KIKVATHSNIALCHQKSNDHFEAKQECNEVLALDKNNVKALYRRGQCNLTINELEDALEDFQKVIQLEPGNKAAANQVIICKQKLKESKNKEKKLYANMFTKLAAND 400 HSP 2 Score: 52.373 bits (124), Expect = 5.006e-7 Identity = 36/119 (30.25%), Postives = 56/119 (47.06%), Query Frame = 1
Query: 451 KGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTF-DNVSFD---ERDVDFEIGDAASFG---LIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHM 786
+G I DG +++ I+ +G G E+P V + G D FD R+ FE S G +I+ ++ MK E+ + NYA+G G S IPP+AT+ +E+ M
Sbjct: 3 EGNKIDLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEFDSSLSRNEPFEF----SLGKGNVIKAFDMGVATMKLGERCFLTCAPNYAYGAAG-SPPAIPPDATLIFELEM 116
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Fly
Match: Fkbp12 (gene:FBgn0013954 transcript:FBtr0086515) HSP 1 Score: 103.605 bits (257), Expect = 1.715e-26 Identity = 53/102 (51.96%), Postives = 63/102 (61.76%), Query Frame = 1
Query: 142 INEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
I G G P NG KV VHY GT DG KFDSSRDR F FT+G+G+VI+ WD GVA + + +LIC P YAYG + G IP NSTL F++EL
Sbjct: 8 IAPGDGSTYPKNGQKVTVHYTGTLD----DGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQLSVGQRAKLICSPDYAYGSRGHPGVIPPNSTLTFDVELL 105
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Fly
Match: Fkbp14 (gene:FBgn0010470 transcript:FBtr0342897) HSP 1 Score: 83.5741 bits (205), Expect = 4.538e-18 Identity = 42/92 (45.65%), Postives = 56/92 (60.87%), Query Frame = 1
Query: 175 NGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFD 447
NG + +HY GT + DG+KFDSS DR+ F+F LG GQVIK WD G+ M E +L P YGD+ G+ IP +TL F++EL +
Sbjct: 43 NGDSLTMHYTGTL---QADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELIN 131
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Fly
Match: Fkbp14 (gene:FBgn0010470 transcript:FBtr0071703) HSP 1 Score: 83.5741 bits (205), Expect = 4.538e-18 Identity = 42/92 (45.65%), Postives = 56/92 (60.87%), Query Frame = 1
Query: 175 NGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFD 447
NG + +HY GT + DG+KFDSS DR+ F+F LG GQVIK WD G+ M E +L P YGD+ G+ IP +TL F++EL +
Sbjct: 43 NGDSLTMHYTGTL---QADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELIN 131
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Zebrafish
Match: fkbp4 (FKBP prolyl isomerase 4 [Source:ZFIN;Acc:ZDB-GENE-030131-514]) HSP 1 Score: 358.607 bits (919), Expect = 8.474e-120 Identity = 189/425 (44.47%), Postives = 278/425 (65.41%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS---IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKDKNEPVKLAENSTA 1362
EDI+P D GVLK + EG G +P+ G KVFVHYVGT DG +FDSSRDR +KFSF LG+GQVIKAWDIGVATMK E+C+L CKP YAYG A GS IP N+TL F++ELFD++G+DI+ +DG I + I+ +G GY P E V++ ++G+ ++ FDER++ FE+GD + GL G+E A + M++ E+++F I Y FG G ++NIPPNAT+ Y+I MK FEK KES+ ++T EKL+ + K + T+ + G A Y+R +S++E++S +++ L L+ LNLA+CYLK D +E CDKALEL+ +EKAL+R+G+AL++ +++ AK F +++ P+N A++QI IC ++E +K+LY +MF K + D + D+ + +N +A
Sbjct: 18 EDITPKKDGGVLKLVKKEGTGTELPMIGDKVFVHYVGTLL----DGSQFDSSRDRGEKFSFELGKGQVIKAWDIGVATMKIGEICQLTCKPEYAYG--AAGSPPKIPPNATLLFQVELFDFRGEDITDDEDGGITRRIITKGEGYTKPNEGATVEVWLEGSHEDRVFDERELKFEVGDGENLGLPLGVEKALQAMEQGEEALFTIKPKYGFGTAGSEKYNIPPNATLQYKIKMKAFEKAKESWEMNTI-EKLEQSVIVKEKGTQYFKEGKYKQAIVQYKRIVSWLEHESSMQPDDEEKAKALRLAAYLNLAMCYLKLQDANPALENCDKALELDANNEKALFRRGEALVVMKEFDMAKVDFQRVIELYPANKAAKSQISICQKHMREQHEKDKRLYANMFQKFAERDAKEADQEKEQDKKQNGSA 435 HSP 2 Score: 55.4546 bits (132), Expect = 8.446e-8 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 1
Query: 454 GKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGT-FDNVSFD-ERD----VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
G+DI+P KDG +++ + +G G E P V + GT D FD RD FE+G +I+ +I MK E YA+G G S IPPNAT+ +++ + DF
Sbjct: 17 GEDITPKKDGGVLKLVKKEGTGTELPMIGDKVFVHYVGTLLDGSQFDSSRDRGEKFSFELGKGQ---VIKAWDIGVATMKIGEICQLTCKPEYAYGAAG-SPPKIPPNATLLFQVELFDF 132
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Zebrafish
Match: fkbp4 (FKBP prolyl isomerase 4 [Source:ZFIN;Acc:ZDB-GENE-030131-514]) HSP 1 Score: 356.681 bits (914), Expect = 6.216e-119 Identity = 189/418 (45.22%), Postives = 276/418 (66.03%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS---IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT---ADKDKNE 1332
EDI+P D GVLK + EG G +P+ G KVFVHYVGT DG +FDSSRDR +KFSF LG+GQVIKAWDIGVATMK E+C+L CKP YAYG A GS IP N+TL F++ELFD++G+DI+ +DG I + I+ +G GY P E V++ ++G+ ++ FDER++ FE+GD + GL G+E A + M++ E+++F I Y FG G ++NIPPNAT+ Y+I MK FEK KES+ ++T EKL+ + K + T+ + G A Y+R +S++E++S +++ L L+ LNLA+CYLK D +E CDKALEL+ +EKAL+R+G+AL++ +++ AK F +++ P+N A++QI IC ++E +K+LY +MF K + D AD++K +
Sbjct: 18 EDITPKKDGGVLKLVKKEGTGTELPMIGDKVFVHYVGTLL----DGSQFDSSRDRGEKFSFELGKGQVIKAWDIGVATMKIGEICQLTCKPEYAYG--AAGSPPKIPPNATLLFQVELFDFRGEDITDDEDGGITRRIITKGEGYTKPNEGATVEVWLEGSHEDRVFDERELKFEVGDGENLGLPLGVEKALQAMEQGEEALFTIKPKYGFGTAGSEKYNIPPNATLQYKIKMKAFEKAKESWEMNTI-EKLEQSVIVKEKGTQYFKEGKYKQAIVQYKRIVSWLEHESSMQPDDEEKAKALRLAAYLNLAMCYLKLQDANPALENCDKALELDANNEKALFRRGEALVVMKEFDMAKVDFQRVIELYPANKAAKSQISICQKHMREQHEKDKRLYANMFQKFAERDAKKEADQEKEQ 428 HSP 2 Score: 55.4546 bits (132), Expect = 8.842e-8 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 1
Query: 454 GKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGT-FDNVSFD-ERD----VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
G+DI+P KDG +++ + +G G E P V + GT D FD RD FE+G +I+ +I MK E YA+G G S IPPNAT+ +++ + DF
Sbjct: 17 GEDITPKKDGGVLKLVKKEGTGTELPMIGDKVFVHYVGTLLDGSQFDSSRDRGEKFSFELGKGQ---VIKAWDIGVATMKIGEICQLTCKPEYAYGAAG-SPPKIPPNATLLFQVELFDF 132
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Zebrafish
Match: fkbp5 (FKBP prolyl isomerase 5 [Source:ZFIN;Acc:ZDB-GENE-030616-630]) HSP 1 Score: 295.819 bits (756), Expect = 2.797e-95 Identity = 162/404 (40.10%), Postives = 250/404 (61.88%), Query Frame = 1
Query: 103 ISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
++P+ D GV K + GV P+ G +VFVHY G G+KFDSS DR++ F F +G+GQVIKAWDI V +M+K EVC ++CKP YAYG + +P NSTL FEIEL +++G++++ +DG I++ I +G GY +P E V + ++G FD RDV F +G++ G+ G++ A +K++K E + + YAFG G+ E +I NA + YE+ +KDFEK KE++ +D KEKL+ A K + T+ + G YA Y+R ++++E + E+ LLL LNLALCYL+ + +T+E C+K +EL+P +EKALYR+G+A ++++++ A F ++L N N A++QI IC KI+EH +KK+Y +MF + + D
Sbjct: 25 VTPNGDSGVCKIVKQHGVEGERPMIGDRVFVHYTGRLL----SGKKFDSSLDRKEPFVFNVGKGQVIKAWDICVCSMQKGEVCLMLCKPEYAYGSAGSPPKVPPNSTLVFEIELLNFRGEELT--EDGGIVRRIKVKGEGYSNPNEGATVHVHLEGWCGGRLFDSRDVTFAVGESEDVGVPLGVDRAMEKLQKGECCLLYLKPKYAFGKEGRKEHDIGSNAELLYEVTLKDFEKAKETWEMD-LKEKLERAVLVKQKGTQYFKAGRYNYAVIQYQRIVNWLEMECGNGKEQLQAIQALLLVAHLNLALCYLRLREYSQTVENCNKVMELDPENEKALYRRGEARLLRNEFSLALMDFKQVLQVNSFNRAARSQILICQHKIREHHERDKKIYANMFQRFAEHDA 421
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Zebrafish
Match: fkbp5 (FKBP prolyl isomerase 5 [Source:ZFIN;Acc:ZDB-GENE-030616-630]) HSP 1 Score: 296.204 bits (757), Expect = 4.035e-95 Identity = 162/404 (40.10%), Postives = 250/404 (61.88%), Query Frame = 1
Query: 103 ISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
++P+ D GV K + GV P+ G +VFVHY G G+KFDSS DR++ F F +G+GQVIKAWDI V +M+K EVC ++CKP YAYG + +P NSTL FEIEL +++G++++ +DG I++ I +G GY +P E V + ++G FD RDV F +G++ G+ G++ A +K++K E + + YAFG G+ E +I NA + YE+ +KDFEK KE++ +D KEKL+ A K + T+ + G YA Y+R ++++E + E+ LLL LNLALCYL+ + +T+E C+K +EL+P +EKALYR+G+A ++++++ A F ++L N N A++QI IC KI+EH +KK+Y +MF + + D
Sbjct: 42 VTPNGDSGVCKIVKQHGVEGERPMIGDRVFVHYTGRLL----SGKKFDSSLDRKEPFVFNVGKGQVIKAWDICVCSMQKGEVCLMLCKPEYAYGSAGSPPKVPPNSTLVFEIELLNFRGEELT--EDGGIVRRIKVKGEGYSNPNEGATVHVHLEGWCGGRLFDSRDVTFAVGESEDVGVPLGVDRAMEKLQKGECCLLYLKPKYAFGKEGRKEHDIGSNAELLYEVTLKDFEKAKETWEMD-LKEKLERAVLVKQKGTQYFKAGRYNYAVIQYQRIVNWLEMECGNGKEQLQAIQALLLVAHLNLALCYLRLREYSQTVENCNKVMELDPENEKALYRRGEARLLRNEFSLALMDFKQVLQVNSFNRAARSQILICQHKIREHHERDKKIYANMFQRFAEHDA 438
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Zebrafish
Match: fkbp1aa (FKBP prolyl isomerase 1Aa [Source:ZFIN;Acc:ZDB-GENE-030131-7275]) HSP 1 Score: 93.5893 bits (231), Expect = 1.005e-22 Identity = 49/108 (45.37%), Postives = 62/108 (57.41%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
GV + I G G P G VHYVG+ + DG KFDSSRDR F F +G+ +VI+ WD GVA M + +L C P +AYG K G IP N+TL F++EL
Sbjct: 2 GVEVETITPGDGSTFPKKGQTCVVHYVGSLT----DGRKFDSSRDRGKPFKFKIGKQEVIRGWDEGVAQMSVGQRAKLTCTPDFAYGSKGHPGVIPPNATLIFDVELI 105
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Xenopus
Match: gcgr (glucagon receptor [Source:Xenbase;Acc:XB-GENE-5918476]) HSP 1 Score: 345.125 bits (884), Expect = 2.568e-114 Identity = 181/428 (42.29%), Postives = 274/428 (64.02%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT-------ADKDKNEPVKLAENST 1359
DI+P DQGVLK I EG GE P+ G KV VHY G + DG +FDSSRDR+DKF+F LG+G+VIKAWDI VATMK E+C+++CKP YAYG + IP N+ L FE+ELFD++G+D++ +DG II+ I +G GY P E V+I +KGT + FDER++ FE+G+ S G+ G+E A ++M+K EK+I + Y FG G ++ IPP A + Y+I +K FEK KES+ ++ +EKL+ K R T+ ++G AT Y++ I ++E++S + EE +L+L+ LNLA CYLK + ++ C+KALEL+P++EK L+R+G+A + +D E+A++ F K+L P+N A+ Q+ C +I++ EKK+Y +MF ++ + ++ +D + EP + EN +
Sbjct: 20 DITPKGDQGVLKLIKKEGTGENTPMIGDKVSVHYTGWLT----DGTQFDSSRDRKDKFTFDLGKGEVIKAWDIAVATMKVGEICQIVCKPEYAYGTSGSPPKIPPNAVLVFEVELFDFQGEDLTQDEDGGIIRRIQVKGEGYSKPNEGAVVEIHVKGTHEGRVFDERELKFEVGEGESIGIPPGVETAIQQMEKGEKAILYLKPKYGFGTTGSEKYQIPPGAELQYDIRLKSFEKAKESWEMN-AEEKLEQGCLVKERGTQYFKDGRYRQATIQYKKIIQWLEHESGLSKEEDAKAKSLILAASLNLAACYLKLGEHRAALDHCNKALELDPSNEKGLFRRGEAYMCTNDLEQARNDFTKVLQLYPANKAARAQLGQCQVRIRQQTEREKKIYANMFQRLAEKESKEVPPAPSDIEMKEPDENGENGS 442 HSP 2 Score: 55.4546 bits (132), Expect = 1.095e-7 Identity = 40/122 (32.79%), Postives = 61/122 (50.00%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVI---KAWDIGVATMKKNEVCELICKPSYAYGDKATGS----IPANSTLKFEIEL 441
ED++ D D G++++I +G G + P GA V +H GT +G FD E + F +GEG+ I + + M+K E L KP Y +G TGS IP + L+++I L
Sbjct: 136 EDLTQDEDGGIIRRIQVKGEGYSKPNEGAVVEIHVKGTH-----EGRVFD-----ERELKFEVGEGESIGIPPGVETAIQQMEKGEKAILYLKPKYGFG--TTGSEKYQIPPGAELQYDIRL 245
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Xenopus
Match: gcgr (glucagon receptor [Source:Xenbase;Acc:XB-GENE-5918476]) HSP 1 Score: 328.176 bits (840), Expect = 7.852e-108 Identity = 173/418 (41.39%), Postives = 266/418 (63.64%), Query Frame = 1
Query: 130 LKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT-------ADKDKNEPVKLAENST 1359
L+ I EG GE P+ G KV VHY G + DG +FDSSRDR+DKF+F LG+G+VIKAWDI VATMK E+C+++CKP YAYG + IP N+ L FE+ELFD++G+D++ +DG II+ I +G GY P E V+I +KGT + FDER++ FE+G+ S G+ G+E A ++M+K EK+I + Y FG G ++ IPP A + Y+I +K FEK KES+ ++ +EKL+ K R T+ ++G AT Y++ I ++E++S + EE +L+L+ LNLA CYLK + ++ C+KALEL+P++EK L+R+G+A + +D E+A++ F K+L P+N A+ Q+ C +I++ EKK+Y +MF ++ + ++ +D + EP + EN +
Sbjct: 23 LQLIKKEGTGENTPMIGDKVSVHYTGWLT----DGTQFDSSRDRKDKFTFDLGKGEVIKAWDIAVATMKVGEICQIVCKPEYAYGTSGSPPKIPPNAVLVFEVELFDFQGEDLTQDEDGGIIRRIQVKGEGYSKPNEGAVVEIHVKGTHEGRVFDERELKFEVGEGESIGIPPGVETAIQQMEKGEKAILYLKPKYGFGTTGSEKYQIPPGAELQYDIRLKSFEKAKESWEMN-AEEKLEQGCLVKERGTQYFKDGRYRQATIQYKKIIQWLEHESGLSKEEDAKAKSLILAASLNLAACYLKLGEHRAALDHCNKALELDPSNEKGLFRRGEAYMCTNDLEQARNDFTKVLQLYPANKAARAQLGQCQVRIRQQTEREKKIYANMFQRLAEKESKEVPPAPSDIEMKEPDENGENGS 435 HSP 2 Score: 55.4546 bits (132), Expect = 1.139e-7 Identity = 40/122 (32.79%), Postives = 61/122 (50.00%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVI---KAWDIGVATMKKNEVCELICKPSYAYGDKATGS----IPANSTLKFEIEL 441
ED++ D D G++++I +G G + P GA V +H GT +G FD E + F +GEG+ I + + M+K E L KP Y +G TGS IP + L+++I L
Sbjct: 129 EDLTQDEDGGIIRRIQVKGEGYSKPNEGAVVEIHVKGTH-----EGRVFD-----ERELKFEVGEGESIGIPPGVETAIQQMEKGEKAILYLKPKYGFG--TTGSEKYQIPPGAELQYDIRL 238
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Xenopus
Match: gcgr (glucagon receptor [Source:Xenbase;Acc:XB-GENE-5918476]) HSP 1 Score: 318.161 bits (814), Expect = 3.584e-104 Identity = 172/428 (40.19%), Postives = 258/428 (60.28%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT-------ADKDKNEPVKLAENST 1359
DI+P DQGVLK I EG GE P+ G KV VHY G + DG +FDSSRDR+DKF+F LG+G+VIKAWDI VATMK E+C+++CKP YAYG + IP N+ L FE+ELFD++G+D++ +DG II+ I +G GY P E V+I +KGT + FDER++ FE+G+ S G+ G+E A ++M+K EK+I + Y FG G ++ IPP A + Y+I +K FEK +G AT Y++ I ++E++S + EE +L+L+ LNLA CYLK + ++ C+KALEL+P++EK L+R+G+A + +D E+A++ F K+L P+N A+ Q+ C +I++ EKK+Y +MF ++ + ++ +D + EP + EN +
Sbjct: 20 DITPKGDQGVLKLIKKEGTGENTPMIGDKVSVHYTGWLT----DGTQFDSSRDRKDKFTFDLGKGEVIKAWDIAVATMKVGEICQIVCKPEYAYGTSGSPPKIPPNAVLVFEVELFDFQGEDLTQDEDGGIIRRIQVKGEGYSKPNEGAVVEIHVKGTHEGRVFDERELKFEVGEGESIGIPPGVETAIQQMEKGEKAILYLKPKYGFGTTGSEKYQIPPGAELQYDIRLKSFEK-----------------------------DGRYRQATIQYKKIIQWLEHESGLSKEEDAKAKSLILAASLNLAACYLKLGEHRAALDHCNKALELDPSNEKGLFRRGEAYMCTNDLEQARNDFTKVLQLYPANKAARAQLGQCQVRIRQQTEREKKIYANMFQRLAEKESKEVPPAPSDIEMKEPDENGENGS 414 HSP 2 Score: 55.4546 bits (132), Expect = 1.160e-7 Identity = 40/122 (32.79%), Postives = 61/122 (50.00%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVI---KAWDIGVATMKKNEVCELICKPSYAYGDKATGS----IPANSTLKFEIEL 441
ED++ D D G++++I +G G + P GA V +H GT +G FD E + F +GEG+ I + + M+K E L KP Y +G TGS IP + L+++I L
Sbjct: 136 EDLTQDEDGGIIRRIQVKGEGYSKPNEGAVVEIHVKGTH-----EGRVFD-----ERELKFEVGEGESIGIPPGVETAIQQMEKGEKAILYLKPKYGFG--TTGSEKYQIPPGAELQYDIRL 245
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Xenopus
Match: adam33 (ADAM metallopeptidase domain 33 [Source:Xenbase;Acc:XB-GENE-988107]) HSP 1 Score: 91.6633 bits (226), Expect = 1.518e-19 Identity = 73/283 (25.80%), Postives = 140/283 (49.47%), Query Frame = 1
Query: 478 DGSIIQTIVNQGIGYES-PKECVPVKISIKGTFD--NVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDS--EFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
+G + + I+ G G +S P++ V + +K + NV ++ + F +GD +IQ +++ + M+ E S+ A Y +G G+S +IPPN+ + E+ + D + + +L + +EKL+ AN+ + R Q + +A Y+ +++ + S EF+ EE+ ++ + NLA LK ++ C+ LE P + KAL+RKG+ L + +Y +A ++ K L P+N ++ + K + N+E +Y+ M G T
Sbjct: 71 NGILKKKILISGKGADSRPRKGQDVTVGLKSMLEDGNVVEEQETLTFTLGDG---DVIQALDLCVQLMEAEETSLIASDAKYCYGKEGRSP-DIPPNSNLNLEVALLDVQDGPDLENL-SGQEKLNLANKKRERGNFYYQQADYVFAINSYDIALNVVNSSSKVEFSLEEEASLLDVKIKCLNNLAASQLKLDHYEAALKSCNMVLEHQPENIKALFRKGKVLAQQGEYSDAITILRKALKLEPANKTIHAELSRLVKKHTDQRNVESAMYKKMLGNPGSAST 348
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Xenopus
Match: adam33 (ADAM metallopeptidase domain 33 [Source:Xenbase;Acc:XB-GENE-988107]) HSP 1 Score: 91.6633 bits (226), Expect = 1.561e-19 Identity = 73/283 (25.80%), Postives = 140/283 (49.47%), Query Frame = 1
Query: 478 DGSIIQTIVNQGIGYES-PKECVPVKISIKGTFD--NVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDS--EFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
+G + + I+ G G +S P++ V + +K + NV ++ + F +GD +IQ +++ + M+ E S+ A Y +G G+S +IPPN+ + E+ + D + + +L + +EKL+ AN+ + R Q + +A Y+ +++ + S EF+ EE+ ++ + NLA LK ++ C+ LE P + KAL+RKG+ L + +Y +A ++ K L P+N ++ + K + N+E +Y+ M G T
Sbjct: 70 NGILKKKILISGKGADSRPRKGQDVTVGLKSMLEDGNVVEEQETLTFTLGDG---DVIQALDLCVQLMEAEETSLIASDAKYCYGKEGRSP-DIPPNSNLNLEVALLDVQDGPDLENL-SGQEKLNLANKKRERGNFYYQQADYVFAINSYDIALNVVNSSSKVEFSLEEEASLLDVKIKCLNNLAASQLKLDHYEAALKSCNMVLEHQPENIKALFRKGKVLAQQGEYSDAITILRKALKLEPANKTIHAELSRLVKKHTDQRNVESAMYKKMLGNPGSAST 347
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Mouse
Match: Fkbp4 (FK506 binding protein 4 [Source:MGI Symbol;Acc:MGI:95543]) HSP 1 Score: 338.961 bits (868), Expect = 7.624e-112 Identity = 181/404 (44.80%), Postives = 263/404 (65.10%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS---IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGK 1302
DISP D+GVLK I EG G P+ G +VFVHY G DG KFDSS DR+DKFSF LG+G+VIKAWDI VATMK EVC + CKP YAYG A GS IP N+TL FE+ELF++KG+D++ +DG II+ I +G GY P + V+++++G + FD+R++ FE+G+ S L G+E A ++M+K E SI + +YAFG++GK + IPP+A + YE+ +K FEK KES+ + ++ EKL+ +N K R T + G A Y++ +S++EY+S F+ EE + L L+ LNLA+C+LK IE C+KALEL+ +EK L+R+G+A + +D++ A++ F K+L PSN A+ Q+ +C + + L EKKLY +MF ++ +
Sbjct: 24 DISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLL----DGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYG--AAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKSFEKAKESWEM-SSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERLAE 420 HSP 2 Score: 52.7582 bits (125), Expect = 6.905e-7 Identity = 39/121 (32.23%), Postives = 62/121 (51.24%), Query Frame = 1
Query: 451 KGKDISPGKDGSIIQTIVNQGIGYESPK--ECVPVKIS---IKGTFDNVSFDERD-VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
+G DISP +D +++ I +G G E+P + V V + + GT + S D +D F++G +I+ +IA MK E YA+G G S IPPNAT+ +E+ + +F
Sbjct: 21 EGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGE---VIKAWDIAVATMKVGEVCHITCKPEYAYGAAG-SPPKIPPNATLVFEVELFEF 137
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Mouse
Match: Fkbp5 (FK506 binding protein 5 [Source:MGI Symbol;Acc:MGI:104670]) HSP 1 Score: 318.546 bits (815), Expect = 5.504e-104 Identity = 182/419 (43.44%), Postives = 258/419 (61.58%), Query Frame = 1
Query: 58 NILSTTMEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
N +T EQ EDI+ D+GVLK + G + P+ G KV+VHY G S DG+KFDSS DR+ F+F+LG+GQVIKAWDIGV+TMKK E+C L+CKP YAYG IP+N+TL FEIEL D+KG+D+ +D +I+ I +G GY +P E VK+ ++G +FD RDV F +G+ + GI+ A KM++ E+ I + Y FG GK ++ I PNA + YE+ +K FEK KES+ +DT KEKL A K + T + G T A Y + +S++E + +++E + LL+ LNLA+CYLK + K +E CDKAL L+ A+EK LYR+G+A ++ +D+E AK F K+L NP N A+ QI +C K KEH ++++Y +MF K + D
Sbjct: 13 NPAATMTEQ---GEDITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLS----DGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLF--EDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKESWEMDT-KEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDRRVYANMFKKFAERDA 421
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Mouse
Match: Fkbp5 (FK506 binding protein 5 [Source:MGI Symbol;Acc:MGI:104670]) HSP 1 Score: 318.546 bits (815), Expect = 5.504e-104 Identity = 182/419 (43.44%), Postives = 258/419 (61.58%), Query Frame = 1
Query: 58 NILSTTMEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
N +T EQ EDI+ D+GVLK + G + P+ G KV+VHY G S DG+KFDSS DR+ F+F+LG+GQVIKAWDIGV+TMKK E+C L+CKP YAYG IP+N+TL FEIEL D+KG+D+ +D +I+ I +G GY +P E VK+ ++G +FD RDV F +G+ + GI+ A KM++ E+ I + Y FG GK ++ I PNA + YE+ +K FEK KES+ +DT KEKL A K + T + G T A Y + +S++E + +++E + LL+ LNLA+CYLK + K +E CDKAL L+ A+EK LYR+G+A ++ +D+E AK F K+L NP N A+ QI +C K KEH ++++Y +MF K + D
Sbjct: 13 NPAATMTEQ---GEDITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLS----DGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLF--EDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKESWEMDT-KEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDRRVYANMFKKFAERDA 421
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Mouse
Match: Fkbp5 (FK506 binding protein 5 [Source:MGI Symbol;Acc:MGI:104670]) HSP 1 Score: 318.546 bits (815), Expect = 5.504e-104 Identity = 182/419 (43.44%), Postives = 258/419 (61.58%), Query Frame = 1
Query: 58 NILSTTMEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
N +T EQ EDI+ D+GVLK + G + P+ G KV+VHY G S DG+KFDSS DR+ F+F+LG+GQVIKAWDIGV+TMKK E+C L+CKP YAYG IP+N+TL FEIEL D+KG+D+ +D +I+ I +G GY +P E VK+ ++G +FD RDV F +G+ + GI+ A KM++ E+ I + Y FG GK ++ I PNA + YE+ +K FEK KES+ +DT KEKL A K + T + G T A Y + +S++E + +++E + LL+ LNLA+CYLK + K +E CDKAL L+ A+EK LYR+G+A ++ +D+E AK F K+L NP N A+ QI +C K KEH ++++Y +MF K + D
Sbjct: 13 NPAATMTEQ---GEDITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLS----DGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLF--EDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKESWEMDT-KEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDRRVYANMFKKFAERDA 421
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Mouse
Match: Fkbp5 (FK506 binding protein 5 [Source:MGI Symbol;Acc:MGI:104670]) HSP 1 Score: 318.546 bits (815), Expect = 5.504e-104 Identity = 182/419 (43.44%), Postives = 258/419 (61.58%), Query Frame = 1
Query: 58 NILSTTMEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
N +T EQ EDI+ D+GVLK + G + P+ G KV+VHY G S DG+KFDSS DR+ F+F+LG+GQVIKAWDIGV+TMKK E+C L+CKP YAYG IP+N+TL FEIEL D+KG+D+ +D +I+ I +G GY +P E VK+ ++G +FD RDV F +G+ + GI+ A KM++ E+ I + Y FG GK ++ I PNA + YE+ +K FEK KES+ +DT KEKL A K + T + G T A Y + +S++E + +++E + LL+ LNLA+CYLK + K +E CDKAL L+ A+EK LYR+G+A ++ +D+E AK F K+L NP N A+ QI +C K KEH ++++Y +MF K + D
Sbjct: 13 NPAATMTEQ---GEDITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLS----DGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLF--EDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKESWEMDT-KEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDRRVYANMFKKFAERDA 421
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. UniProt/SwissProt
Match: sp|Q02790|FKBP4_HUMAN (Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3) HSP 1 Score: 349.362 bits (895), Expect = 4.040e-115 Identity = 181/402 (45.02%), Postives = 266/402 (66.17%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGK 1302
DISP D+GVLK I EG G MP+ G +VFVHY G DG KFDSS DR+DKFSF LG+G+VIKAWDI +ATMK EVC + CKP YAYG + IP N+TL FE+ELF++KG+D++ +DG II+ I +G GY P E V+++++G + + FD+R++ FEIG+ + L G+E A ++M+K E SI + +YAFG++GK ++ IPPNA + YE+H+K FEK KES+ ++ ++EKL+ + K R T + G A Y++ +S++EY+S F++EE L L+ LNLA+C+LK IE C+KALEL+ +EK L+R+G+A + +D+E A++ F K+L P+N A+ Q+ +C +I+ L EKKLY +MF ++ +
Sbjct: 24 DISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLL----DGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMN-SEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. UniProt/SwissProt
Match: sp|Q9TRY0|FKBP4_BOVIN (Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Bos taurus OX=9913 GN=FKBP4 PE=1 SV=4) HSP 1 Score: 346.28 bits (887), Expect = 7.342e-114 Identity = 184/408 (45.10%), Postives = 266/408 (65.20%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADK 1320
DISP D+GVLK I EG G P+ G +VFVHY G DG KFDSS DR+D+FSF LG+G+VIKAWDI VATMK EVC + CKP YAYG + IP N+TL FE+ELF++KG+D++ +DG II+ I +G GY P E V+++++G F + FD R++ FE+G+ S L G+E A ++M+K E SI + YAFG+ GK ++ IPPNA + YEIH+K FEK KES+ + +++EKL+ + K R T + G A Y++ +S++EY+S F+DE+ L L+ LNLA+C+LK IE C+KALEL+ +EK L+R+G+A + +D++ A++ F K+L PSN A+ Q+ +C +I++ L EKKLY +MF ++ + +T K
Sbjct: 24 DISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLL----DGTKFDSSLDRKDRFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGLAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYAKPNEGALVEVALEGYFKDQVFDRRELRFEVGEGESMDLPCGLEKAIQRMEKGEHSIVYLKPRYAFGSAGKEKFQIPPNAELKYEIHLKSFEKAKESWEM-SSEEKLEQSTIVKERGTVYFKEGKYKQAVLQYKKIVSWLEYESSFSDEDAEKAQALRLASHLNLAMCHLKLQAFSAAIENCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKAQLVVCQQRIRKQLEKEKKLYANMFERLAEEETKAK 426 HSP 2 Score: 51.9878 bits (123), Expect = 8.853e-6 Identity = 43/142 (30.28%), Postives = 67/142 (47.18%), Query Frame = 1
Query: 388 KATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKIS-----IKGTFDNVSFDERD-VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
KA S ++ L+ E G DISP +D +++ I +G G E+P V + + GT + S D +D F++G +I+ +IA MK E YA+G G S IPPNAT+ +E+ + +F
Sbjct: 7 KAAESGAQSAPLRLE-------GVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDRFSFDLGKGE---VIKAWDIAVATMKVGEVCHITCKPEYAYGLAG-SPPKIPPNATLVFEVELFEF 137
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. UniProt/SwissProt
Match: sp|P30416|FKBP4_MOUSE (Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Mus musculus OX=10090 GN=Fkbp4 PE=1 SV=5) HSP 1 Score: 338.961 bits (868), Expect = 5.333e-111 Identity = 181/404 (44.80%), Postives = 263/404 (65.10%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS---IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGK 1302
DISP D+GVLK I EG G P+ G +VFVHY G DG KFDSS DR+DKFSF LG+G+VIKAWDI VATMK EVC + CKP YAYG A GS IP N+TL FE+ELF++KG+D++ +DG II+ I +G GY P + V+++++G + FD+R++ FE+G+ S L G+E A ++M+K E SI + +YAFG++GK + IPP+A + YE+ +K FEK KES+ + ++ EKL+ +N K R T + G A Y++ +S++EY+S F+ EE + L L+ LNLA+C+LK IE C+KALEL+ +EK L+R+G+A + +D++ A++ F K+L PSN A+ Q+ +C + + L EKKLY +MF ++ +
Sbjct: 24 DISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLL----DGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYG--AAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKSFEKAKESWEM-SSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERLAE 420 HSP 2 Score: 52.7582 bits (125), Expect = 4.830e-6 Identity = 39/121 (32.23%), Postives = 62/121 (51.24%), Query Frame = 1
Query: 451 KGKDISPGKDGSIIQTIVNQGIGYESPK--ECVPVKIS---IKGTFDNVSFDERD-VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
+G DISP +D +++ I +G G E+P + V V + + GT + S D +D F++G +I+ +IA MK E YA+G G S IPPNAT+ +E+ + +F
Sbjct: 21 EGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGE---VIKAWDIAVATMKVGEVCHITCKPEYAYGAAG-SPPKIPPNATLVFEVELFEF 137
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. UniProt/SwissProt
Match: sp|Q9QVC8|FKBP4_RAT (Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Rattus norvegicus OX=10116 GN=Fkbp4 PE=1 SV=3) HSP 1 Score: 337.421 bits (864), Expect = 1.849e-110 Identity = 177/402 (44.03%), Postives = 263/402 (65.42%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGK 1302
DISP D+GVLK I EG G + G +VFVHY G DG KFDSS DR+DKFSF LG+G+VIKAWDI VATMK EVC + CKP YAYG + IP N+TL FE+ELF++KG+D++ +DG II+ I +G GY P + V+++++G +++ FD+R++ FE+G+ S L G+E A ++M+K E SI + +YAFG++GK + IPP+A + YE+H+K FEK K S+ ++ ++EKL+ +N K R T + G A Y++ +S++EY+S F+ EE + L L+ LNLA+C+LK IE C+KALEL+ +EK L+R+G+A + +D++ A++ F K+L PSN A+ Q+ +C + + L EKKLY +MF ++ +
Sbjct: 24 DISPKQDEGVLKVIKREGTGTETAMIGDRVFVHYTGWLL----DGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEDEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYYNDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVHLKSFEKAKASWEMN-SEEKLEQSNIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERLAE 420 HSP 2 Score: 51.9878 bits (123), Expect = 6.738e-6 Identity = 36/120 (30.00%), Postives = 60/120 (50.00%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIK---AWDIGVATMKKNEVCELICKPSYAYGD--KATGSIPANSTLKFEIEL 441
ED++ D D G++++I G G A P +GA V V G + + FD + + F +GEG+ + + + M+K E + KPSYA+G K IP ++ L++E+ L
Sbjct: 140 EDLTEDEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYY-----NDRLFD-----QRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVHL 249
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. UniProt/SwissProt
Match: sp|P27124|FKBP4_RABIT (Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Oryctolagus cuniculus OX=9986 GN=FKBP4 PE=1 SV=3) HSP 1 Score: 322.398 bits (825), Expect = 1.101e-104 Identity = 177/402 (44.03%), Postives = 263/402 (65.42%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGK 1302
DISP D+GVLK I EG G P+ G +VFVHY G DG KFDSS DR+DKFSF LG+G+VIKAWDI VATMK E+C + CKP YAYG + IP N+TL FE+ELF++KG+D++ +DG II+ I +G GY P + V+++++G + + FD+R++ FE+G+ S L G+E A ++M+K E SI + +YAFGN GK ++ IPP A + YE+H+K FEK KES+ + +++EKL+ + K R T + G A Y++ +S++EY+S F+ EE L L+ LNLA+C+LK +E C+KALEL+ +EK L+R+G+A + +D++ A++ F K+L PSN A+ Q+ +C +I++ + EKKLY +MF ++ +
Sbjct: 24 DISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLL----DGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGELCRITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTDDEDGGIIRRIRTRGEGYARPNDGAIVEVALEGYYKDRLFDQRELRFEVGEGESLDLPCGLEKAIQRMEKGEHSILYLKPSYAFGNAGKEKFQIPPYAELKYEVHLKSFEKAKESWEM-SSEEKLEQSAIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSSEEVQKAQALRLASHLNLAMCHLKLQAFSAAVESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKAQLAVCQQRIRKQIAREKKLYANMFERLAE 420 HSP 2 Score: 53.5286 bits (127), Expect = 2.880e-6 Identity = 38/121 (31.40%), Postives = 61/121 (50.41%), Query Frame = 1
Query: 451 KGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKIS-----IKGTFDNVSFDERD-VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
+G DISP +D +++ I +G G E+P V + + GT + S D +D F++G +I+ +IA MK E YA+G+ G S IPPNAT+ +E+ + +F
Sbjct: 21 EGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGE---VIKAWDIAVATMKVGELCRITCKPEYAYGSAG-SPPKIPPNATLVFEVELFEF 137 HSP 3 Score: 53.1434 bits (126), Expect = 3.746e-6 Identity = 41/120 (34.17%), Postives = 60/120 (50.00%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIK---AWDIGVATMKKNEVCELICKPSYAYGD--KATGSIPANSTLKFEIEL 441
ED++ D D G++++I G G A P +GA V V G + KD FD R F +GEG+ + + + M+K E L KPSYA+G+ K IP + LK+E+ L
Sbjct: 140 EDLTDDEDGGIIRRIRTRGEGYARPNDGAIVEVALEGYY----KD-RLFDQRELR-----FEVGEGESLDLPCGLEKAIQRMEKGEHSILYLKPSYAFGNAGKEKFQIPPYAELKYEVHL 249
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. TrEMBL
Match: I1ZI73 (Peptidylprolyl isomerase OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 841.647 bits (2173), Expect = 0.000e+0 Identity = 428/430 (99.53%), Postives = 430/430 (100.00%), Query Frame = 1
Query: 76 MEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKDKNEPVKLAENSTAH 1365
MEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHA+EFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVLRNNLLLSLRLNLALCYLKSSDCVKTIEECDKALEL+PASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKDKNEPVKLAENSTAH
Sbjct: 1 MEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHASEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVLRNNLLLSLRLNLALCYLKSSDCVKTIEECDKALELDPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKDKNEPVKLAENSTAH 430
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. TrEMBL
Match: A0A3Q3C5Q3 (Peptidylprolyl isomerase OS=Haplochromis burtoni OX=8153 PE=4 SV=1) HSP 1 Score: 366.311 bits (939), Expect = 2.863e-119 Identity = 192/424 (45.28%), Postives = 289/424 (68.16%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT---ADKDKNEPVKLAENS 1356
EDI+P D GVLK I EG G +P++G KVFVHYVGT DG FDSSRDR +KFSF LG+GQVIKAWDIGVATMK E+C+LICKP YAYG + IP ++TL FE+ELF+++G+DI+ +DG II+ I+ +G GY P E V++++ GT D+ FDER++ FEIGD SFGL G+E A M++ E+++F I Y FGN G +++NIP AT+ Y+I + FEK KES+ ++T+ EKL+ ++ K + T+ + G +A+ Y+R +S++E++S ++E+ L L+ LNLA+C+LK + K +E CDK++EL+ ++EKAL+R+G+AL +++E+A+ F K++ P+N A+NQ+ +C +IKE +K++Y +MF K + D+ A+K K+E V+ E++
Sbjct: 21 EDITPKKDGGVLKVIKREGTGTELPMSGDKVFVHYVGTLL----DGTHFDSSRDRGEKFSFELGKGQVIKAWDIGVATMKIGELCQLICKPEYAYGSAGSPPKIPPSATLVFEVELFEFRGEDITEEEDGGIIRRIITKGEGYSKPNEGAAVEVTVIGTCDDSVFDERELKFEIGDGESFGLPAGVEKAIMAMEQGEEAVFTIKPKYGFGNAGNAKFNIPGGATLQYKIKLTAFEKAKESWEMNTS-EKLEQSSIVKEKGTQYFKEGKYKHASVQYKRIVSWLEHESGLSEEDDKKAKALKLAAHLNLAMCFLKLQEPNKALEHCDKSMELDASNEKALFRRGEALFGMNEFEKARDDFQKVVQLYPANKAAKNQVLLCQKRIKEQHEKDKRIYANMFQKFAERDSKKEAEKGKSESVENGEDA 439
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. TrEMBL
Match: A0A3Q0T3L2 (Peptidylprolyl isomerase OS=Amphilophus citrinellus OX=61819 PE=4 SV=1) HSP 1 Score: 364.77 bits (935), Expect = 5.790e-119 Identity = 189/410 (46.10%), Postives = 276/410 (67.32%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKD 1323
EDI+P D GVLK + EG G P+ G KVFVHYVGT DG FDSSRDR +KFSF LG+GQVIKAWD+GVATMK E+C+LICKP YAYG + IP N+TL FE+ELF+++G+DI+ +DG II+ I+ +G GY P E V+++++GT + FDER++ FEIGD SF L G+E A M++ E+++F I Y FG+ G ++NIP AT+ Y+I + FEK KES+ ++TT EKL+ ++ K + T+ + G +A+ Y+R +S++E++S ++E++ L L+ LNLA+CYLK + K +E CDKALEL+ +SEKAL+R+G+AL +++E A+ F K++ P+N A+NQ+ +C +IKE +K++Y +MF K + D+ KD
Sbjct: 19 EDITPKKDGGVLKVVKREGTGTEQPMTGDKVFVHYVGTLL----DGTHFDSSRDRGEKFSFELGKGQVIKAWDVGVATMKIGELCQLICKPEYAYGSAGSPPKIPPNATLVFEVELFEFQGEDITEDEDGGIIRRIITKGEGYSKPNEGAAVEVTVQGTCNERVFDERELKFEIGDGESFNLPAGVEKAIMAMEQGEEALFTIKPKYGFGSAGNVQFNIPGGATLQYKIKLAAFEKAKESWEMNTT-EKLEQSSIVKEKGTQYFKEGRYKHASVQYKRIVSWLEHESGLSEEDEKKAKALQLAAHLNLAMCYLKLQEPNKALEHCDKALELDASSEKALFRRGEALFGMNEFERARDDFQKVVQLYPANKAAKNQVLLCQKRIKEQHEKDKRIYANMFQKFAERDSKVKD 423
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. TrEMBL
Match: A0A3Q4ICR2 (Peptidylprolyl isomerase OS=Neolamprologus brichardi OX=32507 PE=4 SV=1) HSP 1 Score: 364.77 bits (935), Expect = 9.851e-119 Identity = 190/424 (44.81%), Postives = 288/424 (67.92%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT---ADKDKNEPVKLAENS 1356
EDI+P D GVLK I EG G +P++G KVFVHYVGT DG FDSSRDR +KFSF LG+GQVIKAWDIGVATMK E+C+LICKP Y+YG + IP ++TL FE+ELF+++G+DI+ +DG II+ I+ +G GY P E V++++ GT D+ FDER++ FEIGD SFGL G+E A M++ E+++F I Y FGN G +++N+P A + Y+I + FEK KES+ ++T+ EKL+ ++ K + T+ + G +A+ Y+R +S++E++S ++E+ L L+ LNLA+C+LK + K +E CDK++EL+ ++EKAL+RKG+AL +++E+A+ F K++ P+N A+NQ+ +C +IKE +K++Y +MF K + D+ A+K K+E V+ E++
Sbjct: 21 EDITPKKDGGVLKVIKREGTGTELPMSGDKVFVHYVGTLL----DGTHFDSSRDRGEKFSFELGKGQVIKAWDIGVATMKTGELCQLICKPEYSYGSAGSPPKIPPSATLVFEVELFEFRGEDITEEEDGGIIRRIITKGEGYSKPNEGAAVEVTVIGTCDDSVFDERELKFEIGDGESFGLPAGVEKAIMAMEQGEEAVFTIKPKYGFGNAGNAKFNVPGGAILQYKIKLTAFEKAKESWEMNTS-EKLEQSSIVKEKGTQYFKEGKYKHASVQYKRIVSWLEHESGLSEEDDKKAKALQLAAHLNLAMCFLKLQEPNKALEHCDKSMELDASNEKALFRKGEALFGMNEFEKARDDFQKVVQLYPANKAAKNQVLLCQKRIKEQHEKDKRIYANMFQKFAERDSKKEAEKGKSESVENGEDA 439
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. TrEMBL
Match: A0A3P8RFF0 (Peptidylprolyl isomerase OS=Astatotilapia calliptera OX=8154 PE=4 SV=1) HSP 1 Score: 364.385 bits (934), Expect = 1.320e-118 Identity = 191/424 (45.05%), Postives = 288/424 (67.92%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT---ADKDKNEPVKLAENS 1356
EDI+P D GVLK I EG +P++G KVFVHYVGT DG FDSSRDR +KFSF LG+GQVIKAWDIGVATMK E+C+LICKP YAYG + IP ++TL FE+ELF+++G+DI+ +DG II+ I+ +G GY P E V++++ GT D+ FDER++ FEIGD SFGL G+E A M++ E+++F I Y FGN G +++NIP AT+ Y+I + FEK KES+ ++T+ EKL+ ++ K + T+ + G +A+ Y+R +S++E++S ++E+ L L+ LNLA+C+LK + K +E CDK++EL+ ++EKAL+R+G+AL +++E+A+ F K++ P+N A+NQ+ +C +IKE +K++Y +MF K + D+ A+K K+E V+ E++
Sbjct: 21 EDITPKKDGGVLKVIKREGTSTELPMSGDKVFVHYVGTLL----DGTHFDSSRDRGEKFSFELGKGQVIKAWDIGVATMKIGELCQLICKPEYAYGSAGSPPKIPPSATLVFEVELFEFRGEDITEEEDGGIIRRIITKGEGYSKPNEGAAVEVTVIGTCDDSVFDERELKFEIGDGESFGLPAGVEKAIMAMEQGEEAVFTIKPKYGFGNAGNAKFNIPGGATLQYKIKLTAFEKAKESWEMNTS-EKLEQSSIVKEKGTQYFKEGKYKHASVQYKRIVSWLEHESGLSEEDDKKAKALQLAAHLNLAMCFLKLQEPNKALEHCDKSMELDASNEKALFRRGEALFGMNEFEKARDDFQKVVQLYPANKAAKNQVLLCQKRIKEQHEKDKRIYANMFQKFAERDSKKEAEKGKSESVENGEDA 439
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Cavefish
Match: fkbp4 (FKBP prolyl isomerase 4 [Source:NCBI gene;Acc:103045630]) HSP 1 Score: 357.836 bits (917), Expect = 1.622e-119 Identity = 189/419 (45.11%), Postives = 273/419 (65.16%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS---IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT---ADKDKNEP 1335
EDI+P D GVLK + EG G +P+ G KVFVHYVGT DG +FDSSRDR +KFSF LG+GQVIKAWDIGVATM+ E+C+L CKP YAYG A GS IP NSTL F++ELF++ G+DI+ +DG I++ I+ +G GY P E V + ++G ++ FD+RD+ FE+GD + L G+E A + M++ E+S+F I Y FGN G +++NIPP AT+ Y+I + FEK KES+ ++T EKL+ + K + T+ ++G A Y+R +S++E++S E++ L L+ LNL++CYLK D +E CDKALEL+ +EKAL+R+G+AL + ++E AK F +++ PSN A++Q+ +C IKE +K+LY +MF K + D A++ K EP
Sbjct: 18 EDITPKKDGGVLKLVKKEGTGTELPMTGDKVFVHYVGTLL----DGTQFDSSRDRGEKFSFELGKGQVIKAWDIGVATMRIGEICQLFCKPEYAYG--AAGSPPKIPPNSTLIFQVELFEFHGEDITDEEDGGIVRRIITKGEGYTKPNEGASVDVHLEGQYEGRVFDDRDLKFEVGDGENLDLPPGVEKALQAMEQGEESLFTIKPKYGFGNTGYAKFNIPPGATLQYKIKLTAFEKAKESWEMNTC-EKLEQSTIVKEKGTQYFKDGKYKQAAVQYKRIVSWLEHESSLQGEDEEKAKALRLAAHLNLSMCYLKLHDPNPALENCDKALELSANNEKALFRRGEALFVMKEFERAKDDFQRVIQLYPSNKAAKSQVVLCQKHIKEQHEKDKRLYANMFQKFAERDAKKEAEQAKKEP 429 HSP 2 Score: 52.7582 bits (125), Expect = 5.363e-7 Identity = 37/120 (30.83%), Postives = 58/120 (48.33%), Query Frame = 1
Query: 454 GKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGT-FDNVSFD-ERD----VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
G+DI+P KDG +++ + +G G E P V + GT D FD RD FE+G +I+ +I M+ E YA+G G S IPPN+T+ +++ + +F
Sbjct: 17 GEDITPKKDGGVLKLVKKEGTGTELPMTGDKVFVHYVGTLLDGTQFDSSRDRGEKFSFELGKGQ---VIKAWDIGVATMRIGEICQLFCKPEYAYGAAG-SPPKIPPNSTLIFQVELFEF 132
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Cavefish
Match: fkbp5 (FKBP prolyl isomerase 5 [Source:ZFIN;Acc:ZDB-GENE-030616-630]) HSP 1 Score: 275.018 bits (702), Expect = 4.388e-87 Identity = 150/405 (37.04%), Postives = 238/405 (58.77%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
DI+P D+GV K + G P+ G +V+VHY G +G+KFDSS DR++ F F +G+GQVI+AWDIGV +M+K EVC L+CKP YAYG + +P NSTL FE+EL ++G++++ +DG I++ I +G GY +P E V + ++G + F RD+ F +G++ G+ G++ A +KM+K E + + Y FG GK+E+ I PNA + YE+ +KDF+K G +A Y+R ++++E + E++ + LLL LNLALCYL+ + +T+E C+K +EL+ +EKALYR+G+A ++++++ A F ++L NPSN A++QI IC KI+EH +K++Y +MF + + D
Sbjct: 65 DITPGKDRGVCKIVKRHGTEGERPMIGDRVYVHYTGKLL----NGKKFDSSYDRKEPFVFNVGKGQVIRAWDIGVCSMQKGEVCLLLCKPDYAYGSAGSPPKVPPNSTLLFEVELLSFRGEELT--EDGGILRRIKVKGEGYNNPNEGATVHVHLEGRCGDRLFQSRDITFVVGESEDKGIPLGVDRAMEKMQKGECCLLYLKPRYGFGKEGKAEYGIGPNAELLYEVTLKDFDKA-----------------------------GRYYHAVIQYQRIVTWLEMECGLGKEQQQAIHALLLVAYLNLALCYLRLQEYAQTVENCNKVMELDSKNEKALYRRGEARLLRNEFSLALVDFRQVLQVNPSNRAARSQIVICQRKIREHHEQDKRIYANMFQRFAEHDA 434 HSP 2 Score: 51.6026 bits (122), Expect = 1.039e-6 Identity = 35/126 (27.78%), Postives = 60/126 (47.62%), Query Frame = 1
Query: 439 LFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDN-----VSFDERD-VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFE 798
LF+ +G DI+PGKD + + + G E P V + G N S+D ++ F +G +I+ +I M+K E + +YA+G+ G S +PPN+T+ +E+ + F
Sbjct: 58 LFNSQGIDITPGKDRGVCKIVKRHGTEGERPMIGDRVYVHYTGKLLNGKKFDSSYDRKEPFVFNVGKGQ---VIRAWDIGVCSMQKGEVCLLLCKPDYAYGSAG-SPPKVPPNSTLLFEVELLSFR 179
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Cavefish
Match: fkbp1aa (peptidyl-prolyl cis-trans isomerase FKBP1A [Source:NCBI gene;Acc:103030299]) HSP 1 Score: 93.5893 bits (231), Expect = 8.104e-23 Identity = 49/108 (45.37%), Postives = 62/108 (57.41%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
GV + I G G P G VHYVG+ + DG KFDSSRDR F F +G+ +VI+ WD GVA M + +L C P +AYG K G IP N+TL F++EL
Sbjct: 2 GVEVETITPGDGSTFPKKGQTCVVHYVGSLT----DGRKFDSSRDRGKPFKFKIGKQEVIRGWDEGVAQMSVGQRAKLTCTPDFAYGSKGHPGIIPPNATLIFDVELL 105
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Cavefish
Match: fkbp1ab (peptidyl-prolyl cis-trans isomerase FKBP1A-like [Source:NCBI gene;Acc:103040235]) HSP 1 Score: 92.4337 bits (228), Expect = 2.302e-22 Identity = 47/108 (43.52%), Postives = 63/108 (58.33%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
GV + I G G P G VHYVG+ + DG KFDSSRDR+ F F +G+ +VI+ W+ GV M + +L C P +AYG+K G IP N+TL F++EL
Sbjct: 2 GVEIETITPGDGRTFPKKGQTCVVHYVGSLT----DGRKFDSSRDRDKPFKFKIGKQEVIRGWEEGVVQMSVGQRAKLTCSPDFAYGNKGHPGIIPPNATLIFDVELL 105
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Cavefish
Match: fkbp1b (FKBP prolyl isomerase 1B [Source:NCBI gene;Acc:103027308]) HSP 1 Score: 85.5001 bits (210), Expect = 3.129e-19 Identity = 45/109 (41.28%), Postives = 60/109 (55.05%), Query Frame = 1
Query: 121 QGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
GV + I+ G G P G VHY+G ++G+KFDSSRDR F F +G +VIK W+ GVA M + ++ C P AYG G IP N+TL F++EL
Sbjct: 58 MGVEVETISPGDGRTFPKKGQTCVVHYIGML----QNGKKFDSSRDRNKPFKFKIGRQEVIKGWEEGVAQMSLGQRAKITCTPDMAYGATGHPGVIPPNATLIFDVELL 162
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Sea Lamprey
Match: fkbp1aa (FKBP prolyl isomerase 1Aa [Source:ZFIN;Acc:ZDB-GENE-030131-7275]) HSP 1 Score: 94.7449 bits (234), Expect = 1.431e-23 Identity = 48/108 (44.44%), Postives = 63/108 (58.33%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
GV + I G G+ P G V VHY GT +DG+KFDSSRDR+ F F +G+ +VI+ W+ GVA M + L C P +AYG G IP N+TL F++EL
Sbjct: 27 GVQVETITPGDGQTFPKKGQTVVVHYTGTL----EDGKKFDSSRDRDKPFKFKIGKQEVIRGWEEGVAQMSVGQRARLTCSPDFAYGAIGHPGVIPPNATLLFDVELL 130
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Sea Lamprey
Match: fkbp1b (FKBP prolyl isomerase 1B [Source:ZFIN;Acc:ZDB-GENE-040426-1785]) HSP 1 Score: 77.7962 bits (190), Expect = 3.484e-18 Identity = 40/82 (48.78%), Postives = 51/82 (62.20%), Query Frame = 1
Query: 202 VGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
VGTF ++G+KFDSSRDR+ F FTLG+ QVIK W+ GV M + C P AYG+ G IP N+TL F++EL
Sbjct: 1 VGTF----RNGKKFDSSRDRKKPFRFTLGKQQVIKGWEEGVGQMSLGMRARITCTPDMAYGETGHPGVIPPNTTLIFDVELL 78
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004854.1 (pep scaffold:Pmarinus_7.0:GL501075:9618:21951:-1 gene:ENSPMAG00000004388.1 transcript:ENSPMAT00000004854.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 77.411 bits (189), Expect = 2.418e-17 Identity = 41/92 (44.57%), Postives = 52/92 (56.52%), Query Frame = 1
Query: 175 NGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDK-ATGSIPANSTLKFEIELFD 447
G + +HY GT +DG +FDSS R F FTLG GQVIK WD G+ M + E +L+ P YGD+ A IP +TL FE+EL
Sbjct: 49 KGDTLHMHYTGTL----EDGTEFDSSIPRNQPFIFTLGTGQVIKGWDQGLLGMCEGEKRKLVIPPELGYGDRGAPPKIPGGATLVFEVELLQ 136
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Sea Lamprey
Match: fkbp6 (FKBP prolyl isomerase 6 [Source:ZFIN;Acc:ZDB-GENE-050302-4]) HSP 1 Score: 73.559 bits (179), Expect = 1.134e-14 Identity = 70/293 (23.89%), Postives = 133/293 (45.39%), Query Frame = 1
Query: 478 DGSIIQTIVNQGIGYESPKECVPVKISIKG-------TFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFE---KVKESFSLDTTKEK-------LDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKG 1305
+G +++ ++ +G G P E V+++ +D+ + + + A ++ G+E+ M K E + F + ++YA+G +G IPPN+T+ E+ + F V + +++ + K L A +T Q G A Y +++ +E ++EE+ LL + LNLALCYL+ + T+ +AL + P + KA +R GQA +M DY ++ + P + +++K AK +E E+++ + MF G G
Sbjct: 36 NGGVLKIVLQKGSGDIVP-ELSAVRVNYNAYLEYSDEPYDSSHLRKEESRLWLSKGA---VMPGLEVGLLTMCKGELARFLVRSDYAYGALGCPP-RIPPNSTLLLEVELLGFIDCINVDDYYTMTPEERKRLKLEKVLRVAVNERTAGNAHFQAGRYDRAMHKYLKTLRILENAHLSSNEEQSQMEASLLKVLLNLALCYLRRNRPSSTVHYALRALRVQPNNVKACFRLGQAHLMLGDYVRSRYYLLRAQSMAPVHPVITHELKALEAKWQEFNRWEREMCRRMFKGTGGG 323 HSP 2 Score: 60.4622 bits (145), Expect = 2.075e-10 Identity = 40/110 (36.36%), Postives = 59/110 (53.64%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATG---SIPANSTLKFEIELF 444
GVLK ++ +G G+ +P A V V+Y E E +DSS R+++ L +G V+ ++G+ TM K E+ + + YAYG A G IP NSTL E+EL
Sbjct: 38 GVLKIVLQKGSGDIVPELSA-VRVNYNAYL---EYSDEPYDSSHLRKEESRLWLSKGAVMPGLEVGLLTMCKGELARFLVRSDYAYG--ALGCPPRIPPNSTLLLEVELL 141
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Sea Lamprey
Match: fkbp11 (FKBP prolyl isomerase 11 [Source:ZFIN;Acc:ZDB-GENE-030616-357]) HSP 1 Score: 63.5438 bits (153), Expect = 4.167e-12 Identity = 38/97 (39.18%), Postives = 50/97 (51.55%), Query Frame = 1
Query: 175 NGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDK-ATGSIPANSTLKFEIELFDWKGKD 462
G + VHY G KDG FD+S R D LG+ QVI W+ G+ M E +L+ P AYG + A SIPA++ L FE EL + K+
Sbjct: 48 QGDTLHVHYTGRL----KDGSVFDTSAMR-DPLQVELGKKQVIPGWEQGLLGMCVGEKRKLVIPPHLAYGKRGAPPSIPADAVLTFETELVSLRHKE 139
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Yeast
Match: FPR1 (Peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function; N-terminally propionylated in vivo; mutation is functionally complemented by human FKBP1A [Source:SGD;Acc:S000005079]) HSP 1 Score: 83.9593 bits (206), Expect = 3.668e-20 Identity = 44/102 (43.14%), Postives = 56/102 (54.90%), Query Frame = 1
Query: 142 INEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
I+ G G P G V +HY GT ++G+KFDSS DR F +G GQVIK WD+G+ + E L YAYG + G IP NSTL F++EL
Sbjct: 14 ISPGDGATFPKTGDLVTIHYTGTL----ENGQKFDSSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVGEKARLTIPGPYAYGPRGFPGLIPPNSTLVFDVELL 111
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Yeast
Match: FPR2 (Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking; relocalizes from nucleus to vacuole upon DNA replication stress; mutation is functionally complemented by human FKBP2 [Source:SGD;Acc:S000002927]) HSP 1 Score: 73.1738 bits (178), Expect = 3.994e-16 Identity = 48/116 (41.38%), Postives = 67/116 (57.76%), Query Frame = 1
Query: 112 DNDQGVLKKI-INEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKAT-GSIPANSTLKFEIELFDWK 453
D + G++K+I + + + +AMP G KV VHY G+ + G FDSS R +F LG G+VIK WD GVA M E +L S AYG++ G IP ++ L F++EL D K
Sbjct: 22 DLEIGIIKRIPVEDCLIKAMP--GDKVKVHYTGSL---LESGTVFDSSYSRGSPIAFELGVGRVIKGWDQGVAGMCVGEKRKLQIPSSLAYGERGVPGVIPPSADLVFDVELVDVK 132
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Yeast
Match: FPR3 (Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; affects expression of multiple genes via its role in nucleosome assembly; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; FPR3 has a paralog, FPR4, that arose from the whole genome duplication [Source:SGD;Acc:S000004539]) HSP 1 Score: 72.0182 bits (175), Expect = 3.999e-14 Identity = 39/93 (41.94%), Postives = 53/93 (56.99%), Query Frame = 1
Query: 175 NGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWK 453
GA+V + Y+G K+G+ FD + + F+F LG G+VIK WDIGVA M +I YAYG +A IPANS L F+++L K
Sbjct: 323 RGARVGMRYIGKL----KNGKVFDKNTSGK-PFAFKLGRGEVIKGWDIGVAGMSVGGERRIIIPAPYAYGKQALPGIPANSELTFDVKLVSMK 410
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Yeast
Match: FPR4 (Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers [Source:SGD;Acc:S000004441]) HSP 1 Score: 69.3218 bits (168), Expect = 2.438e-13 Identity = 38/92 (41.30%), Postives = 52/92 (56.52%), Query Frame = 1
Query: 178 GAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWK 453
G +V + YVG K+G+ FD + + F F LG+G+VIK WDIGVA M ++ YAYG +A IPANS L F+++L K
Sbjct: 306 GTRVGMRYVGKL----KNGKVFDKNT-KGKPFVFKLGQGEVIKGWDIGVAGMAVGGERRIVIPAPYAYGKQALPGIPANSELTFDVKLVSMK 392
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Nematostella
Match: EDO43207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZA5]) HSP 1 Score: 260.766 bits (665), Expect = 9.162e-82 Identity = 155/400 (38.75%), Postives = 233/400 (58.25%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKS-IFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKV 1296
DI+P D GV K+I++EG G M G V V YVG F +GE+FDS+ F F LGE VI+ WDIGVATMKK E L CKP YAYG + IP N+TL+F +EL DWKG +++ G + + I+ +G G+ P V + G++D F+ER+V+F G+ GL++G+E A M EKS IF Y G G + +PPNA +TY I +K FE KE++ L + EK+ A + K + T+ ++G A + Y I +E F++EE+ + + + LN+A C+LK + K I+ C+KAL+++ + KAL+R+G+AL+ DYE++K F ++L +P N +A+ Q+KI +K+H EKKLY ++F ++
Sbjct: 29 DITPKKDGGVRKRILSEGHGAEMANVGCTVVVRYVGKFL----NGEEFDSNTGGV-PFEFVLGESVVIQGWDIGVATMKKGEKALLTCKPEYAYGKQGGSKIPPNTTLQFIVELLDWKGINVT--NKGEVSKVILEKGEGHARPNTGAVVNAHVTGSYDGKVFEEREVEFTFGEGTEAGLLEGVEEAIGNMTNKEKSKIFIQPGKYGVGPEGNPQLGLPPNALITYIIDLKHFENFKEAWEL-SNDEKITTALKVKDKGTKFFKDGKYKIACRQYAVVIRVLE--GYFDEEEEKAVDPIKCAGHLNIAACHLKLGNNFKCIKACNKALDIDKENIKALFRRGKALLNLKDYEKSKEDFTQVLELDPKNREAREQLKIVNGMLKDHHQKEKKLYSNIFERL 418 HSP 2 Score: 60.077 bits (144), Expect = 8.234e-10 Identity = 49/170 (28.82%), Postives = 83/170 (48.82%), Query Frame = 1
Query: 454 GKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDN-VSFDERD----VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVT--YATKLY-ERSISY 939
G DI+P KDG + + I+++G G E V + G F N FD +F +G++ +IQG +I MKK EK++ YA+G G S+ IPPN T+ + + + D++ + + + +K L+ T + N +VT Y K++ ER + +
Sbjct: 27 GVDITPKKDGGVRKRILSEGHGAEMANVGCTVVVRYVGKFLNGEEFDSNTGGVPFEFVLGESV---VIQGWDIGVATMKKGEKALLTCKPEYAYGKQGGSK--IPPNTTLQFIVELLDWKGINVTNKGEVSKVILEKGEGHARPNTGAVVNAHVTGSYDGKVFEEREVEF 191
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Nematostella
Match: EDO31332 (Peptidyl-prolyl cis-trans isomerase [Source:UniProtKB/TrEMBL;Acc:A7SY88]) HSP 1 Score: 87.0409 bits (214), Expect = 5.362e-21 Identity = 46/90 (51.11%), Postives = 52/90 (57.78%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA 393
GV K + G G++ P G V VHY GT + DG+KFDSSRDR F F LG GQVIK WD GVA M + L C P YAYG K
Sbjct: 2 GVDVKTVQPGDGKSFPKAGQTVSVHYTGTLT----DGKKFDSSRDRGKPFQFKLGAGQVIKGWDEGVAQMSLGQKATLTCTPDYAYGPKG 87
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Nematostella
Match: EDO40282 (Peptidyl-prolyl cis-trans isomerase [Source:UniProtKB/TrEMBL;Acc:A7S7R3]) HSP 1 Score: 72.4034 bits (176), Expect = 1.609e-15 Identity = 39/92 (42.39%), Postives = 51/92 (55.43%), Query Frame = 1
Query: 172 INGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDK-ATGSIPANSTLKFEIELF 444
+ G + +HY G +DG +FDSS R + F FTLG GQVIK WD G+ M E +L+ YGD+ A IP +TL FE+EL
Sbjct: 36 VKGDSLHMHYTGKL----EDGTEFDSSIPRGEPFVFTLGTGQVIKGWDQGLLNMCAGEKRKLVIPSDMGYGDRGAPPKIPGGATLIFEVELL 123
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Nematostella
Match: EDO34418 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPD7]) HSP 1 Score: 74.3294 bits (181), Expect = 1.676e-15 Identity = 38/96 (39.58%), Postives = 57/96 (59.38%), Query Frame = 1
Query: 175 NGAKVFVHYVGTFSGGEKDGEKFDSSRDRE---DKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWK 453
N KV H V ++G +DG FD++RD F FT+G G VIK ++ GV M + +++ P+ AYG K +G +PAN+TL + +ELFD +
Sbjct: 16 NKTKVGDHVVVHYTGWMQDGSLFDTTRDHRKGYQPFEFTIGGGTVIKGFEQGVTGMCVGQKRKIVIPPALAYGKKGSGDVPANTTLTYNLELFDVR 111
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Nematostella
Match: EDO47498 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLX5]) HSP 1 Score: 70.4774 bits (171), Expect = 4.142e-14 Identity = 37/94 (39.36%), Postives = 54/94 (57.45%), Query Frame = 1
Query: 178 GAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATG-SIPANSTLKFEIELFDWKG 456
G + +HY G + +G KFDSS DR F FTLG+G VI+ W+ G+ M E +L P AYG+ G +IP ++TL ++EL + +G
Sbjct: 45 GDTLSMHYTGRLA----NGNKFDSSLDRGKTFDFTLGKGMVIQGWEQGLLDMCIGEKRKLTIPPHLAYGENGAGAAIPPHATLYMDVELVEIQG 134
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Medaka
Match: fkbp4 (FKBP prolyl isomerase 4 [Source:NCBI gene;Acc:101164056]) HSP 1 Score: 358.607 bits (919), Expect = 8.191e-120 Identity = 182/406 (44.83%), Postives = 275/406 (67.73%), Query Frame = 1
Query: 97 EDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
EDI+P D GVLK I EG G +P+ G KVFVHYVGT DG FDSSRDR +KFSF LG+GQVIKAWDIGVATMK E+C+L+CKP YAYG + IP NSTL FE+ELFD++G+DI+ +DG II+ I+ +G GY P E V+++++GT D FDER++ FEIGD SF L G+E A M++ E+++F I Y +GN G ++ NIP AT+ Y+I + FEK KES+ ++T EKL+ ++ K + T+ ++G A+ Y++ +S++E++S ++E++ L L+ LNLA+CYLK + + +E CDKALE++ ++EKAL+R+G+AL +++++A+ F +++ P+N A++Q+ +C ++KE +K++Y +MF K + D+
Sbjct: 19 EDITPKKDGGVLKVIKREGTGTELPMTGDKVFVHYVGTLL----DGTHFDSSRDRGEKFSFELGKGQVIKAWDIGVATMKVGELCQLVCKPEYAYGSAGSPPKIPPNSTLVFEVELFDFRGEDITEDEDGGIIRRIITKGEGYSKPNEGATVEVTVQGTHDERIFDERELKFEIGDGESFNLPAGLEKAIMAMEQGEEALFTIKPKYGYGNAGNAKLNIPAGATLQYKIKLTAFEKAKESWEMNTP-EKLEQSSIIKEKGTQYFKDGKYKQASVQYKKIVSWLEHESGLSEEDEKKAKTLRLAAHLNLAMCYLKLHEPNQALENCDKALEMDASNEKALFRRGEALFAMNEFDKARDDFQRVVQLYPANKAAKSQVMLCQKRLKEQHEKDKRIYANMFQKFAERDS 419 HSP 2 Score: 59.3066 bits (142), Expect = 4.447e-9 Identity = 41/120 (34.17%), Postives = 59/120 (49.17%), Query Frame = 1
Query: 454 GKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGT-FDNVSFD-ERD----VDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDF 795
G+DI+P KDG +++ I +G G E P V + GT D FD RD FE+G +I+ +I MK E YA+G+ G S IPPN+T+ +E+ + DF
Sbjct: 18 GEDITPKKDGGVLKVIKREGTGTELPMTGDKVFVHYVGTLLDGTHFDSSRDRGEKFSFELGKGQ---VIKAWDIGVATMKVGELCQLVCKPEYAYGSAG-SPPKIPPNSTLVFEVELFDF 133
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Medaka
Match: fkbp5 (peptidyl-prolyl cis-trans isomerase FKBP5 [Source:NCBI gene;Acc:101157675]) HSP 1 Score: 278.87 bits (712), Expect = 5.746e-88 Identity = 154/405 (38.02%), Postives = 241/405 (59.51%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKAT-GSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
D++P+ DQGV+K + G P+ G +V VHY G G+KFD SR+R++ FSF G+GQV+K+WDIGV +M++ EVC L+CKP YAYG IP N+++ FE+EL ++G+ ++ DG +++ I +G GY P + V + ++G D FD R+V F +G+A G+ G++ A KM+K E + + Y FG+ GK+E+ I P+ + YE+ +KDF + KES+ +D EK++ A K + + + G A Y+R IS++E + E+ +L+ LNLALC+L+ D ++ C+K LEL+ +EKA YR+G+A + ++++ AK F K+L NP+N A+ QI IC KIKEH +KK+Y +MF K + D
Sbjct: 64 DLTPNKDQGVIKVVQCPGFDVDRPMIGDRVTVHYTGRLL----TGKKFDCSRERKEPFSFNAGKGQVLKSWDIGVLSMQRGEVCTLLCKPEYAYGSAGNPDKIPPNASVVFEMELLSFEGESLT--DDGGVVRRIKIKGEGYSQPNDGASVDVYLEGRCDGRLFDSRNVSFIVGEAEDKGVPLGVDRAMDKMQKGECCLLYLKPKYGFGSKGKAEYKIGPDRDIVYEVTLKDFRRAKESWEMDIY-EKVNLAPGVKNKGNQYFKTGQYHQAVIQYQRIISWLEMECGTGIEQHQRIQEFVLTAHLNLALCFLRLKDFSHVVDNCNKVLELDENNEKAFYRRGEARLYRNEFGLAKEDFQKVLQVNPANQAARAQILICQNKIKEHHEQDKKIYANMFQKFAEQDA 461
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Medaka
Match: fkbp5 (peptidyl-prolyl cis-trans isomerase FKBP5 [Source:NCBI gene;Acc:101157675]) HSP 1 Score: 278.87 bits (712), Expect = 8.199e-88 Identity = 154/405 (38.02%), Postives = 241/405 (59.51%), Query Frame = 1
Query: 100 DISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDT 1311
D++P+ DQGV+K + G P+ G +V VHY G G+KFD SR+R++ FSF G+GQV+K+WDIGV +M++ EVC L+CKP YAYG IP N+++ FE+EL ++G+ ++ DG +++ I +G GY P + V + ++G D FD R+V F +G+A G+ G++ A KM+K E + + Y FG+ GK+E+ I P+ + YE+ +KDF + KES+ +D EK++ A K + + + G A Y+R IS++E + E+ +L+ LNLALC+L+ D ++ C+K LEL+ +EKA YR+G+A + ++++ AK F K+L NP+N A+ QI IC KIKEH +KK+Y +MF K + D
Sbjct: 77 DLTPNKDQGVIKVVQCPGFDVDRPMIGDRVTVHYTGRLL----TGKKFDCSRERKEPFSFNAGKGQVLKSWDIGVLSMQRGEVCTLLCKPEYAYGSAGNPDKIPPNASVVFEMELLSFEGESLT--DDGGVVRRIKIKGEGYSQPNDGASVDVYLEGRCDGRLFDSRNVSFIVGEAEDKGVPLGVDRAMDKMQKGECCLLYLKPKYGFGSKGKAEYKIGPDRDIVYEVTLKDFRRAKESWEMDIY-EKVNLAPGVKNKGNQYFKTGQYHQAVIQYQRIISWLEMECGTGIEQHQRIQEFVLTAHLNLALCFLRLKDFSHVVDNCNKVLELDENNEKAFYRRGEARLYRNEFGLAKEDFQKVLQVNPANQAARAQILICQNKIKEHHEQDKKIYANMFQKFAEQDA 474
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Medaka
Match: ENSORLT00000027603.1 (peptidyl-prolyl cis-trans isomerase FKBP1A [Source:NCBI gene;Acc:101166420]) HSP 1 Score: 101.679 bits (252), Expect = 9.808e-26 Identity = 53/108 (49.07%), Postives = 66/108 (61.11%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELF 444
GV + I G G+ P G VFVHYVGT +G+KFDSSRDR + F F LG G+VI+ WD GVA M ++ +L C P +AYG + IP NSTL FE+EL
Sbjct: 2 GVDVETIRPGDGKTFPQKGRTVFVHYVGTL----MNGKKFDSSRDRGEPFQFKLGAGEVIRGWDDGVARMSVGQLAKLTCSPDFAYGSRGYPPIIPPNSTLIFEVELL 105
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Medaka
Match: ENSORLT00000018301.2 (peptidyl-prolyl cis-trans isomerase FKBP1A [Source:NCBI gene;Acc:101168621]) HSP 1 Score: 94.3597 bits (233), Expect = 4.251e-23 Identity = 49/108 (45.37%), Postives = 63/108 (58.33%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELF 444
GV + + G G P G +V VHYVGT + DG+ FDSSR R F F +G +VI+ W+ GVA M + +LIC P YAYG K G IP N+TL F++EL
Sbjct: 2 GVEIETLTPGDGRTFPKKGQRVVVHYVGTLA----DGKVFDSSRSRGKPFKFKIGHQEVIRGWEEGVAQMSVGQRAKLICSPDYAYGSKGHPGVIPPNATLTFDVELL 105
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Planmine SMEST
Match: SMESG000026331.1 (SMESG000026331.1) HSP 1 Score: 841.647 bits (2173), Expect = 0.000e+0 Identity = 428/430 (99.53%), Postives = 430/430 (100.00%), Query Frame = 1
Query: 76 MEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHANEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVXXXXXXXXXXXXXXXCYLKSSDCVKTIEECDKALELNPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKDKNEPVKLAENSTAH 1365
MEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHA+EFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVLRNNLLLSLRLNLALCYLKSSDCVKTIEECDKALEL+PASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKDKNEPVKLAENSTAH
Sbjct: 1 MEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGSIPANSTLKFEIELFDWKGKDISPGKDGSIIQTIVNQGIGYESPKECVPVKISIKGTFDNVSFDERDVDFEIGDAASFGLIQGIEIACKKMKKCEKSIFEISANYAFGNIGKSEWNIPPNATVTYEIHMKDFEKVKESFSLDTTKEKLDHASEFKTRATEKLQNGNVTYATKLYERSISYIEYDSEFNDEEKVLRNNLLLSLRLNLALCYLKSSDCVKTIEECDKALELDPASEKALYRKGQALIMKSDYEEAKSMFGKILLNNPSNSQAQNQIKICLAKIKEHLNIEKKLYQSMFSKVGKGDTADKDKNEPVKLAENSTAH 430
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Planmine SMEST
Match: SMESG000062712.1 (SMESG000062712.1) HSP 1 Score: 101.679 bits (252), Expect = 7.763e-26 Identity = 56/112 (50.00%), Postives = 67/112 (59.82%), Query Frame = 1
Query: 121 QGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKA-TGSIPANSTLKFEIELFDWK 453
GV+ + I +G P G V VHYVGT + +G+KFDSSRDR + F F +G G VIK WD GV M K E +L C P YAYG K G IP NSTL FE+ L D+K
Sbjct: 1 MGVVVETIEQGDCVNYPKVGQNVTVHYVGTLT----NGKKFDSSRDRNEPFKFKIGTGSVIKGWDEGVLKMSKGEKAKLTCSPDYAYGSKGYPGLIPPNSTLVFEVLLIDFK 108
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Planmine SMEST
Match: SMESG000028286.1 (SMESG000028286.1) HSP 1 Score: 87.0409 bits (214), Expect = 1.472e-20 Identity = 49/111 (44.14%), Postives = 60/111 (54.05%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWK 453
GV + I G P G V VHY GT + +G+KFDSSRDR F +G G+VIK WD GVA + E +L C P YAYG + IP NS L F++EL K
Sbjct: 2 GVQIERIKPGDESTYPKKGQTVEVHYTGTLT----NGKKFDSSRDRNRPLKFKIGMGEVIKGWDEGVAQLSLGERAKLTCSPDYAYGSEGIQDVIPPNSVLIFDVELISIK 108
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Planmine SMEST
Match: SMESG000004790.1 (SMESG000004790.1) HSP 1 Score: 87.0409 bits (214), Expect = 1.472e-20 Identity = 49/111 (44.14%), Postives = 60/111 (54.05%), Query Frame = 1
Query: 124 GVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELFDWK 453
GV + I G P G V VHY GT + +G+KFDSSRDR F +G G+VIK WD GVA + E +L C P YAYG + IP NS L F++EL K
Sbjct: 2 GVQIERIKPGDESTYPKKGQTVEVHYTGTLT----NGKKFDSSRDRNRPLKFKIGMGEVIKGWDEGVAQLSLGERAKLTCSPDYAYGSEGIQDVIPPNSVLIFDVELISIK 108
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Planmine SMEST
Match: SMESG000026974.1 (SMESG000026974.1) HSP 1 Score: 77.7962 bits (190), Expect = 7.457e-17 Identity = 46/106 (43.40%), Postives = 58/106 (54.72%), Query Frame = 1
Query: 130 LKKIINEGVGEAMPINGAKVFVHYVGTFSGGEKDGEKFDSSRDREDKFSFTLGEGQVIKAWDIGVATMKKNEVCELICKPSYAYGDKATGS-IPANSTLKFEIELF 444
+KK IN+ +A +G + +HY GT DG KFDSS DR D FTLG GQVIK WD+G+ M E +L YGD + IP +TL FE+EL
Sbjct: 36 IKKRINDCTEKAK--DGDMIHMHYTGTLY---DDGSKFDSSLDRGDPLKFTLGTGQVIKGWDLGIQGMCVGEKRKLFIPSHLGYGDNGSPPKIPPKATLVFEVELM 136 The following BLAST results are available for this feature:
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 4
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of peptidyl prolyl cis trans isomerase FKBP-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030477 ID=SMED30030477|Name=peptidyl prolyl cis trans isomerase FKBP-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1405bpback to top protein sequence of SMED30030477-orf-1 >SMED30030477-orf-1 ID=SMED30030477-orf-1|Name=SMED30030477-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=431bp MEQYAGFEDISPDNDQGVLKKIINEGVGEAMPINGAKVFVHYVGTFSGGEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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