U1 small nuclear ribonucleoprotein 70 kDa

Overview
NameU1 small nuclear ribonucleoprotein 70 kDa
Smed IDSMED30030431
Length (bp)1299
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of U1 small nuclear ribonucleoprotein 70 kDa (SMED30030431) t-SNE clustered cells

Violin plots show distribution of expression levels for U1 small nuclear ribonucleoprotein 70 kDa (SMED30030431) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of U1 small nuclear ribonucleoprotein 70 kDa (SMED30030431) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for U1 small nuclear ribonucleoprotein 70 kDa (SMED30030431) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030431

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 15

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30030431h1SMcG0020473 SmedASXL_010862SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30030431h1SMcG0020473 Contig49433newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30030431h1SMcG0020473 Contig49433uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30030431h1SMcG0020473 dd_Smed_v4_633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gamma neoblastSMED30030431h1SMcG0020473 dd_Smed_v6_633_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30030431h1SMcG0020473 dd_Smed_v6_633_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Human
Match: SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150])

HSP 1 Score: 218.394 bits (555), Expect = 6.804e-66
Identity = 119/184 (64.67%), Postives = 144/184 (78.26%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Human
Match: SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150])

HSP 1 Score: 218.009 bits (554), Expect = 1.151e-65
Identity = 119/184 (64.67%), Postives = 144/184 (78.26%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Human
Match: SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150])

HSP 1 Score: 173.326 bits (438), Expect = 6.372e-52
Identity = 98/164 (59.76%), Postives = 123/164 (75.00%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNA 542
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+  + A
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSTTQLA 164
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Human
Match: SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150])

HSP 1 Score: 173.326 bits (438), Expect = 6.372e-52
Identity = 98/164 (59.76%), Postives = 123/164 (75.00%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNA 542
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+  + A
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSTTQLA 164
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Human
Match: SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150])

HSP 1 Score: 173.326 bits (438), Expect = 6.372e-52
Identity = 98/164 (59.76%), Postives = 123/164 (75.00%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNA 542
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+  + A
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSTTQLA 164
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Celegans
Match: rnp-7 (RNP (RRM RNA binding domain) containing [Source:UniProtKB/TrEMBL;Acc:Q09584])

HSP 1 Score: 198.364 bits (503), Expect = 9.645e-60
Identity = 104/184 (56.52%), Postives = 135/184 (73.37%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIER---PKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRT 599
            MTA+LPPNLLALF AR P+ +LPP +     K+ ++ P TG+AQY++LFEDP +TP    V T+ E +E KR++K E +AYKVEQ +A WNP E P  ++DPY+TLFV RINY+T+ESK+RREFE YG IK + M+ +    KPRGY FIEY  + +MH AYK ADG K+DG R++VD ER RT
Sbjct:    1 MTAFLPPNLLALFEARPPVQYLPPCQDLLVDKNAKRAPMTGVAQYIQLFEDPKDTPAKIPVVTKAEAKEEKRRQKDELLAYKVEQGIATWNPAENPRASEDPYRTLFVGRINYETSESKLRREFEAYGKIKKLTMVHDEA-GKPRGYAFIEYSDKAEMHTAYKKADGIKVDGKRLVVDYERGRT 183
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Celegans
Match: rnp-7 (RNP (RRM RNA binding domain) containing [Source:UniProtKB/TrEMBL;Acc:Q09584])

HSP 1 Score: 198.364 bits (503), Expect = 9.645e-60
Identity = 104/184 (56.52%), Postives = 135/184 (73.37%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIER---PKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRT 599
            MTA+LPPNLLALF AR P+ +LPP +     K+ ++ P TG+AQY++LFEDP +TP    V T+ E +E KR++K E +AYKVEQ +A WNP E P  ++DPY+TLFV RINY+T+ESK+RREFE YG IK + M+ +    KPRGY FIEY  + +MH AYK ADG K+DG R++VD ER RT
Sbjct:    1 MTAFLPPNLLALFEARPPVQYLPPCQDLLVDKNAKRAPMTGVAQYIQLFEDPKDTPAKIPVVTKAEAKEEKRRQKDELLAYKVEQGIATWNPAENPRASEDPYRTLFVGRINYETSESKLRREFEAYGKIKKLTMVHDEA-GKPRGYAFIEYSDKAEMHTAYKKADGIKVDGKRLVVDYERGRT 183
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Celegans
Match: cpf-2 (Cleavage and Polyadenylation Factor [Source:UniProtKB/TrEMBL;Acc:O45577])

HSP 1 Score: 55.8398 bits (133), Expect = 2.019e-8
Identity = 26/81 (32.10%), Postives = 44/81 (54.32%), Query Frame = 3 
Query:  339 GTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            G     +++FV  I+YD +E  IR  F   G + +I+M+ +    KP+GY FIE+   +    A +N +G ++ G  + VD
Sbjct:   12 GNDRSQRSVFVGNISYDVSEDTIRSIFSKAGNVLSIKMVHDRETGKPKGYGFIEFPDIQTAEVAIRNLNGYELSGRILRVD 92
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Celegans
Match: cpf-2 (Cleavage and Polyadenylation Factor [Source:UniProtKB/TrEMBL;Acc:O45577])

HSP 1 Score: 55.8398 bits (133), Expect = 2.019e-8
Identity = 26/81 (32.10%), Postives = 44/81 (54.32%), Query Frame = 3 
Query:  339 GTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            G     +++FV  I+YD +E  IR  F   G + +I+M+ +    KP+GY FIE+   +    A +N +G ++ G  + VD
Sbjct:   12 GNDRSQRSVFVGNISYDVSEDTIRSIFSKAGNVLSIKMVHDRETGKPKGYGFIEFPDIQTAEVAIRNLNGYELSGRILRVD 92
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Celegans
Match: rsp-4 (Probable splicing factor, arginine/serine-rich 4 [Source:UniProtKB/Swiss-Prot;Acc:Q09511])

HSP 1 Score: 46.9802 bits (110), Expect = 2.461e-6
Identity = 22/77 (28.57%), Postives = 42/77 (54.55%), Query Frame = 3 
Query:  360 TLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVER 590
            +L +  ++Y TT + +RR FE YG I  + + ++  + + +G+ F+ +   RD   A    DGK +DG  + V + +
Sbjct:   20 SLKIDNLSYQTTPNDLRRTFERYGDIGDVHIPRDKYSRQSKGFGFVRFYERRDAEHALDRTDGKLVDGRELRVTLAK 96
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Fly
Match: snRNP-U1-70K (gene:FBgn0016978 transcript:FBtr0331375)

HSP 1 Score: 228.409 bits (581), Expect = 7.005e-70
Identity = 121/183 (66.12%), Postives = 154/183 (84.15%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKL-PYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT YLPPNLLALFAAR+PI F+PP+++  H +K   Y G+A+++  FEDP +TP+P  VETR E+ ER+R+EKAEQ+AYK+E+++ALW+P EI N T+DP++TLF+ARINYDT+ESK+RREFE YGPIK I +I +  + KP+GY FIEYEHERDMHAAYK+ADGKKID  RVLVDVER+RTV
Sbjct:    1 MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTV 183
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Fly
Match: snRNP-U1-70K (gene:FBgn0016978 transcript:FBtr0079355)

HSP 1 Score: 228.409 bits (581), Expect = 7.005e-70
Identity = 121/183 (66.12%), Postives = 154/183 (84.15%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKL-PYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT YLPPNLLALFAAR+PI F+PP+++  H +K   Y G+A+++  FEDP +TP+P  VETR E+ ER+R+EKAEQ+AYK+E+++ALW+P EI N T+DP++TLF+ARINYDT+ESK+RREFE YGPIK I +I +  + KP+GY FIEYEHERDMHAAYK+ADGKKID  RVLVDVER+RTV
Sbjct:    1 MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTV 183
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089616)

HSP 1 Score: 60.8474 bits (146), Expect = 1.275e-10
Identity = 27/77 (35.06%), Postives = 45/77 (58.44%), Query Frame = 3 
Query:  357 KTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVE 587
            + + V  +N +T++ K+R  F  YGPI+ I+M+ +    + RG+CFI +E   D  AA  +  G ++DG R+ VD  
Sbjct:   12 RCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFS 88
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089615)

HSP 1 Score: 60.4622 bits (145), Expect = 3.597e-10
Identity = 27/77 (35.06%), Postives = 45/77 (58.44%), Query Frame = 3 
Query:  357 KTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVE 587
            + + V  +N +T++ K+R  F  YGPI+ I+M+ +    + RG+CFI +E   D  AA  +  G ++DG R+ VD  
Sbjct:   59 RCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFS 135
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089619)

HSP 1 Score: 60.4622 bits (145), Expect = 3.597e-10
Identity = 27/77 (35.06%), Postives = 45/77 (58.44%), Query Frame = 3 
Query:  357 KTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVE 587
            + + V  +N +T++ K+R  F  YGPI+ I+M+ +    + RG+CFI +E   D  AA  +  G ++DG R+ VD  
Sbjct:   59 RCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFS 135
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Zebrafish
Match: snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:ZFIN;Acc:ZDB-GENE-040825-2])

HSP 1 Score: 208.764 bits (530), Expect = 8.727e-62
Identity = 118/184 (64.13%), Postives = 139/184 (75.54%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI FLP + +  H  H   PY GIA +++ FEDP + P P + ETR+E+ ERKR+EK E+    VE +L LW+P+   N   D +KTLFVARINYDTTESK+RREFEVYGPIK I ++ N    KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPFLPQLGKLPHEKHHNQPYCGIAPFIRHFEDPRDAPPPTRAETREERLERKRREKMERRQVVVEGELKLWDPHNDANAQGDAFKTLFVARINYDTTESKLRREFEVYGPIKRIYIVYNKKTGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Zebrafish
Match: snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:ZFIN;Acc:ZDB-GENE-040825-2])

HSP 1 Score: 167.548 bits (423), Expect = 7.105e-50
Identity = 98/161 (60.87%), Postives = 118/161 (73.29%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAY 533
            MT +LPPNLLALFA RDPI FLP + +  H  H   PY GIA +++ FEDP + P P + ETR+E+ ERKR+EK E+    VE +L LW+P+   N   D +KTLFVARINYDTTESK+RREFEVYGPIK I ++ N    KPRGY FIEYEHERDMH+AY
Sbjct:    1 MTQFLPPNLLALFAPRDPIPFLPQLGKLPHEKHHNQPYCGIAPFIRHFEDPRDAPPPTRAETREERLERKRREKMERRQVVVEGELKLWDPHNDANAQGDAFKTLFVARINYDTTESKLRREFEVYGPIKRIYIVYNKKTGKPRGYAFIEYEHERDMHSAY 161
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Zebrafish
Match: snrnp35 (small nuclear ribonucleoprotein 35 (U11/U12) [Source:NCBI gene;Acc:569999])

HSP 1 Score: 79.337 bits (194), Expect = 1.221e-16
Identity = 41/99 (41.41%), Postives = 64/99 (64.65%), Query Frame = 3 
Query:  306 LALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            LA + PN    G  DP  TLFVAR+N  TTE K+R  F  +G I+ +R++++V+    + Y FIEY+ ER +  A+++A+   +D + +LVDVE+ RT+
Sbjct:   35 LARYKPNRGVCG--DPDLTLFVARLNPQTTEEKLRDVFSKFGDIRRLRLVRDVVTGFSKRYAFIEYKEERSLKRAWRDANKLILDQYELLVDVEQERTL 131
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Zebrafish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 55.4546 bits (132), Expect = 1.324e-8
Identity = 24/73 (32.88%), Postives = 41/73 (56.16%), Query Frame = 3 
Query:  363 LFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            LF+  ++YDTTE  +   F  YG I  + +I++    + RG+ F+ +E+  D   A    +GK++DG  + VD
Sbjct:    7 LFIGGLSYDTTEQSLEEAFSKYGTIAKVDVIRDRETDRSRGFGFVTFENPEDAKDAMAAMNGKQVDGRMIRVD 79
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Zebrafish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 55.0694 bits (131), Expect = 2.670e-8
Identity = 24/73 (32.88%), Postives = 41/73 (56.16%), Query Frame = 3 
Query:  363 LFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            LF+  ++YDTTE  +   F  YG I  + +I++    + RG+ F+ +E+  D   A    +GK++DG  + VD
Sbjct:   24 LFIGGLSYDTTEQSLEEAFSKYGTIAKVDVIRDRETDRSRGFGFVTFENPEDAKDAMAAMNGKQVDGRMIRVD 96
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Xenopus
Match: snrnp70 (small nuclear ribonucleoprotein, U1 70kDa subunit [Source:NCBI gene;Acc:493488])

HSP 1 Score: 215.698 bits (548), Expect = 1.567e-64
Identity = 117/184 (63.59%), Postives = 142/184 (77.17%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDP+ +LPP+++  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+    VE +L +W+P+   N   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ N  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPVPYLPPLDKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQDVENELKIWDPHNDQNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYNKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Xenopus
Match: snrnp70 (small nuclear ribonucleoprotein, U1 70kDa subunit [Source:NCBI gene;Acc:493488])

HSP 1 Score: 171.785 bits (434), Expect = 6.548e-48
Identity = 104/185 (56.22%), Postives = 133/185 (71.89%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNA-KPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDP+ +LPP+++  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+    VE +L +W+P+   N   D +KTLFVAR+NYDTTESK+RREFEVYGPIK + ++  +L A K  G     ++H   + AAYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPVPYLPPLDKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQDVENELKIWDPHNDQNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRVCILGGLLCACKLIGSVLPFWKHC--VTAAYKHADGKKIDGRRVLVDVERGRTV 183
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Xenopus
Match: adat1 (adenosine deaminase, tRNA-specific 1 [Source:Xenbase;Acc:XB-GENE-1002540])

HSP 1 Score: 70.8626 bits (172), Expect = 3.153e-13
Identity = 38/99 (38.38%), Postives = 60/99 (60.61%), Query Frame = 3 
Query:  306 LALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            LA + PN+   G  DP+ TL+VAR++  TTE K++  F  YG IK IR++++ +    +GY FIEY+ E  +  A+++A+   ID   + VD E  R +
Sbjct:   36 LARYVPNKGVIG--DPHLTLYVARLSQQTTEEKLKEVFSRYGDIKRIRLVRDFITGFSKGYAFIEYKQENAIMKAHRDANKLVIDQREIFVDFELERNL 132
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Xenopus
Match: mcm3ap (minichromosome maintenance complex component 3 associated protein [Source:Xenbase;Acc:XB-GENE-981006])

HSP 1 Score: 57.3806 bits (137), Expect = 2.479e-8
Identity = 23/76 (30.26%), Postives = 44/76 (57.89%), Query Frame = 3 
Query:  354 YKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
             +++FV  I Y+ TE +++  F   GP+ + R++ +    KP+GY F EY+ +    +A +N +G++  G  + VD
Sbjct:   15 LRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVD 90
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Xenopus
Match: mcm3ap (minichromosome maintenance complex component 3 associated protein [Source:Xenbase;Acc:XB-GENE-981006])

HSP 1 Score: 57.3806 bits (137), Expect = 2.579e-8
Identity = 23/76 (30.26%), Postives = 44/76 (57.89%), Query Frame = 3 
Query:  354 YKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
             +++FV  I Y+ TE +++  F   GP+ + R++ +    KP+GY F EY+ +    +A +N +G++  G  + VD
Sbjct:   15 LRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVD 90
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Mouse
Match: Snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:MGI Symbol;Acc:MGI:98341])

HSP 1 Score: 218.009 bits (554), Expect = 1.030e-65
Identity = 119/184 (64.67%), Postives = 144/184 (78.26%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Mouse
Match: Snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:MGI Symbol;Acc:MGI:98341])

HSP 1 Score: 174.866 bits (442), Expect = 1.283e-52
Identity = 98/161 (60.87%), Postives = 121/161 (75.16%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAY 533
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH  Y
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHCEY 161
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Mouse
Match: Snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:MGI Symbol;Acc:MGI:98341])

HSP 1 Score: 118.242 bits (295), Expect = 8.279e-32
Identity = 53/84 (63.10%), Postives = 66/84 (78.57%), Query Frame = 3 
Query:  291 KVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNA 542
            +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+  + A
Sbjct:   31 EVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSTTQLA 114
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Mouse
Match: Snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:MGI Symbol;Acc:MGI:98341])

HSP 1 Score: 91.2781 bits (225), Expect = 6.857e-22
Identity = 60/109 (55.05%), Postives = 78/109 (71.56%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVAR 377
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVAR 109
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Mouse
Match: Snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:MGI Symbol;Acc:MGI:98341])

HSP 1 Score: 86.2705 bits (212), Expect = 1.922e-20
Identity = 40/53 (75.47%), Postives = 45/53 (84.91%), Query Frame = 3 
Query:  444 IRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            I M+ +  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 IHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 53
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. UniProt/SwissProt
Match: sp|P17133|RU17_DROME (U1 small nuclear ribonucleoprotein 70 kDa OS=Drosophila melanogaster OX=7227 GN=snRNP-U1-70K PE=1 SV=2)

HSP 1 Score: 228.409 bits (581), Expect = 7.021e-69
Identity = 121/183 (66.12%), Postives = 154/183 (84.15%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKL-PYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT YLPPNLLALFAAR+PI F+PP+++  H +K   Y G+A+++  FEDP +TP+P  VETR E+ ER+R+EKAEQ+AYK+E+++ALW+P EI N T+DP++TLF+ARINYDT+ESK+RREFE YGPIK I +I +  + KP+GY FIEYEHERDMHAAYK+ADGKKID  RVLVDVER+RTV
Sbjct:    1 MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTV 183
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. UniProt/SwissProt
Match: sp|P08621|RU17_HUMAN (U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2)

HSP 1 Score: 218.009 bits (554), Expect = 5.530e-65
Identity = 119/184 (64.67%), Postives = 144/184 (78.26%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. UniProt/SwissProt
Match: sp|Q62376|RU17_MOUSE (U1 small nuclear ribonucleoprotein 70 kDa OS=Mus musculus OX=10090 GN=Snrnp70 PE=1 SV=2)

HSP 1 Score: 218.009 bits (554), Expect = 7.207e-65
Identity = 119/184 (64.67%), Postives = 144/184 (78.26%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. UniProt/SwissProt
Match: sp|Q1RMR2|RU17_BOVIN (U1 small nuclear ribonucleoprotein 70 kDa OS=Bos taurus OX=9913 GN=SNRNP70 PE=2 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 1.020e-64
Identity = 119/184 (64.67%), Postives = 144/184 (78.26%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI +LPP+E+  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L +W+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ +  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. UniProt/SwissProt
Match: sp|Q66II8|RU17_XENTR (U1 small nuclear ribonucleoprotein 70 kDa OS=Xenopus tropicalis OX=8364 GN=snrnp70 PE=2 SV=1)

HSP 1 Score: 215.698 bits (548), Expect = 8.299e-64
Identity = 117/184 (63.59%), Postives = 142/184 (77.17%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDP+ +LPP+++  H  H   PY GIA Y++ FEDP + P P + ETR+E+ ERKR+EK E+    VE +L +W+P+   N   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I M+ N  + KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPVPYLPPLDKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQDVENELKIWDPHNDQNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYNKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. TrEMBL
Match: A4V6K0 (SnRNP70K protein (Fragment) OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 322.013 bits (824), Expect = 5.581e-104
Identity = 197/210 (93.81%), Postives = 203/210 (96.67%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTVXXXXXXXXXXXXXXXXXXXXEQNSKYTT 686
            MTAYLPPNLLALFAARDPI F  PIERPKHHR LPYTGIAQYVKLFEDPSETPIPPKVETR+EKRERKRKEKAEQIAYKVEQDLALWNPNEIP+GTKDPYKTLFVARINYDTTE+KIRREFE YGPIKTIRM+KN +N KPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVER+RTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT
Sbjct:    6 MTAYLPPNLLALFAARDPIPFAIPIERPKHHRPLPYTGIAQYVKLFEDPSETPIPPKVETREEKRERKRKEKAEQIAYKVEQDLALWNPNEIPSGTKDPYKTLFVARINYDTTENKIRREFEGYGPIKTIRMVKNAMNNKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERARTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT 215
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. TrEMBL
Match: A0A0X3NZD7 (RRM domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR158543 PE=4 SV=1)

HSP 1 Score: 246.899 bits (629), Expect = 1.323e-76
Identity = 130/181 (71.82%), Postives = 154/181 (85.08%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRT 599
            MT YLPPNLLALFA RDPI FLPPIE+ KHHRKLPYTG+AQ++  FEDPSETP P ++ETR+E++ERKR+EK EQ  YK+EQDLALWNP + PN T +PY TLFVAR+NYDT+E K+RREF+VYGPIK I MIK+V   KPRGY FIE+EHERDMHAA K+A+ +KIDGHR+L D+ER RT
Sbjct:    1 MTQYLPPNLLALFAPRDPIPFLPPIEKHKHHRKLPYTGVAQFLGEFEDPSETPAPARIETREERKERKRREKQEQANYKLEQDLALWNPKKNPNATGNPYNTLFVARLNYDTSEHKLRREFDVYGPIKKISMIKDVSTGKPRGYAFIEFEHERDMHAANKDANNRKIDGHRILTDIERGRT 181
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. TrEMBL
Match: A0A0X3Q2F0 (RRM domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR158543 PE=4 SV=1)

HSP 1 Score: 248.825 bits (634), Expect = 3.323e-76
Identity = 130/181 (71.82%), Postives = 154/181 (85.08%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRT 599
            MT YLPPNLLALFA RDPI FLPPIE+ KHHRKLPYTG+AQ++  FEDPSETP P ++ETR+E++ERKR+EK EQ  YK+EQDLALWNP + PN T +PY TLFVAR+NYDT+E K+RREF+VYGPIK I MIK+V   KPRGY FIE+EHERDMHAA K+A+ +KIDGHR+L D+ER RT
Sbjct:    1 MTQYLPPNLLALFAPRDPIPFLPPIEKHKHHRKLPYTGVAQFLGEFEDPSETPAPARIETREERKERKRREKQEQANYKLEQDLALWNPKKNPNATGNPYNTLFVARLNYDTSEHKLRREFDVYGPIKKISMIKDVSTGKPRGYAFIEFEHERDMHAANKDANNRKIDGHRILTDIERGRT 181
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. TrEMBL
Match: I6T8W7 (U1 small nuclear ribonucleoprotein 70 kD OS=Spirometra erinaceieuropaei OX=99802 PE=2 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 6.144e-76
Identity = 129/181 (71.27%), Postives = 154/181 (85.08%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRT 599
            MT YLPPNLLALFA RDPI FLPPIE+ KHHRKLPYTG+AQ++  FEDPSETP P ++ETR+E++ERKR+EK EQ  YK+EQDLALWNP + PN T +PY TLFVAR+NYDT+E K+RREF+VYGPIK I MIK++   KPRGY FIE+EHERDMHAA K+A+ +KIDGHR+L D+ER RT
Sbjct:    1 MTQYLPPNLLALFAPRDPIPFLPPIEKHKHHRKLPYTGVAQFLGEFEDPSETPAPARIETREERKERKRREKQEQANYKLEQDLALWNPKKNPNATGNPYNTLFVARLNYDTSEHKLRREFDVYGPIKRISMIKDIATGKPRGYAFIEFEHERDMHAANKDANNRKIDGHRILTDIERGRT 181
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. TrEMBL
Match: A0A1I8IJB1 (RRM domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 244.202 bits (622), Expect = 7.825e-76
Identity = 122/182 (67.03%), Postives = 157/182 (86.26%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT YLPPNLLALFA RDP+ +LPP++RP+H+R LPYTG+AQ++  FEDP +TP+  KVE+RDE+RER+ KE+ EQ AYK+EQDLA+W+P++ PN T DP+ TLFVARI+YDTTE+K+RREFE YGPI+T+R++ +  N +PRGY FIEYEH+RDMH AYK+A+GKKIDG RVLVD ER+RT+
Sbjct:    1 MTQYLPPNLLALFAPRDPLNYLPPLDRPQHYRTLPYTGVAQFLGEFEDPKDTPVVAKVESRDERRERRNKERQEQAAYKLEQDLAMWDPHDNPNATSDPFNTLFVARIDYDTTEAKLRREFETYGPIRTVRIVHDKRNGRPRGYAFIEYEHDRDMHTAYKHAEGKKIDGRRVLVDAERARTI 182
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Cavefish
Match: ENSAMXT00000055483.1 (small nuclear ribonucleoprotein U1 subunit 70 [Source:NCBI gene;Acc:103033076])

HSP 1 Score: 216.468 bits (550), Expect = 1.161e-64
Identity = 120/184 (65.22%), Postives = 142/184 (77.17%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI FLP +E+  H  H   PY+GIA ++K FEDP + P P + ETR+E+ ERKR+EK E+    VE +L LW+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I ++ N    KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPFLPQLEKLPHEKHHNQPYSGIAPFIKHFEDPRDAPPPTRAETREERLERKRREKMERRQTVVETELKLWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIYIVYNKRTGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Cavefish
Match: ENSAMXT00000031735.1 (small nuclear ribonucleoprotein U1 subunit 70 [Source:NCBI gene;Acc:103033076])

HSP 1 Score: 164.851 bits (416), Expect = 1.500e-45
Identity = 101/184 (54.89%), Postives = 122/184 (66.30%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI FLP +E+  H  H   PY+GIA ++K FEDP + P P + ETR+E+ ERKR+EK E+    VE +L LW+P+  PN   D +KTLFVAR+ Y                     ++ N    KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPFLPQLEKLPHEKHHNQPYSGIAPFIKHFEDPRDAPPPTRAETREERLERKRREKMERRQTVVETELKLWDPHNDPNAQGDAFKTLFVARVIY---------------------IVYNKRTGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 163
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Cavefish
Match: snrnp35 (small nuclear ribonucleoprotein 35 (U11/U12) [Source:NCBI gene;Acc:569999])

HSP 1 Score: 75.0998 bits (183), Expect = 3.110e-15
Identity = 38/105 (36.19%), Postives = 60/105 (57.14%), Query Frame = 3 
Query:  303 DLALW---NPNEIPNG--TKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            D A+W   N    PN   T DP  TLFVAR+N  T+E  +   F  +G I+ +R++++ +    +GY FIEY+ ER +  A+++A+   +D   + VD E  RT+
Sbjct:   28 DRAIWRAMNARYRPNKAVTGDPQLTLFVARLNKQTSEEDLNNVFSTFGDIRRVRLVRDAVTGFSKGYAFIEYKEERSLMKAWRDANKMVVDQSELFVDFELERTL 132
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Cavefish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 56.9954 bits (136), Expect = 5.373e-9
Identity = 32/105 (30.48%), Postives = 52/105 (49.52%), Query Frame = 3 
Query:  282 IAYKVEQDLALWNPNEIPNG-----TKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            +++   Q L L+ P+  P         D  K LF+  ++YDTTE  +   F  YG I  + +I++    + RG+ F+ +E+  D   A    +GK IDG  + VD
Sbjct:   15 VSFSHSQQLRLFTPSRGPEKRNTRKMSDEGK-LFIGGLSYDTTEQSLEDAFSKYGTIAKVDVIRDRETDRSRGFGFVTFENPDDAKDAMVAMNGKSIDGRMIRVD 118
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Cavefish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 56.6102 bits (135), Expect = 6.343e-9
Identity = 32/105 (30.48%), Postives = 52/105 (49.52%), Query Frame = 3 
Query:  282 IAYKVEQDLALWNPNEIP-----NGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            +++   Q L L+ P+  P         D  K LF+  ++YDTTE  +   F  YG I  + +I++    + RG+ F+ +E+  D   A    +GK IDG  + VD
Sbjct:   15 VSFSHSQQLRLFTPSRGPEKRNTRKMSDEGK-LFIGGLSYDTTEQSLEDAFSKYGTIAKVDVIRDRETDRSRGFGFVTFENPDDAKDAMVAMNGKSIDGRMIRVD 118
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Sea Lamprey
Match: snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:ZFIN;Acc:ZDB-GENE-040825-2])

HSP 1 Score: 216.853 bits (551), Expect = 2.847e-69
Identity = 119/184 (64.67%), Postives = 147/184 (79.89%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHR--KLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT YLPPNLLALFA RDP+ FLPP+ +  H +  + PY+GIA YV LFEDP + P P + ET++E+ ERKR+EK E+ A ++E++L LW+ +   N   D +KTLFVARINYDT+ESK+RREFEVYGPI+ I MI N ++ KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER+RTV
Sbjct:    1 MTQYLPPNLLALFAPRDPVPFLPPLAKLPHEKVHRQPYSGIAVYVHLFEDPKDAPPPTRAETKEERMERKRREKIEKRAQEIEEELKLWDAHTDTNVQGDAFKTLFVARINYDTSESKLRREFEVYGPIRRITMIYNKVSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGKRVLVDVERARTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Sea Lamprey
Match: snrnp70 (small nuclear ribonucleoprotein 70 (U1) [Source:ZFIN;Acc:ZDB-GENE-040825-2])

HSP 1 Score: 204.912 bits (520), Expect = 1.137e-64
Identity = 116/183 (63.39%), Postives = 144/183 (78.69%), Query Frame = 3 
Query:   69 LPPNLLALFAARDPITFLPPIERPKHHR--KLPYTGIAQYVKLFE---DPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            LPPNLLALFA RDP+ FLPP+ +  H +  + PY+GIA YV LFE   DP + P P + ET++E+ ERKR+EK E+ A ++E++L LW+ +   N   D +KTLFVARINYDT+ESK+RREFEVYGPI+ I MI N ++ KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER+RTV
Sbjct:    1 LPPNLLALFAPRDPVPFLPPLAKLPHEKVHRQPYSGIAVYVHLFEEIGDPKDAPPPTRAETKEERMERKRREKIEKRAQEIEEELKLWDAHTDTNVQGDAFKTLFVARINYDTSESKLRREFEVYGPIRRITMIYNKVSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGKRVLVDVERARTV 183
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Sea Lamprey
Match: srsf2b (serine and arginine rich splicing factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-2420])

HSP 1 Score: 52.373 bits (124), Expect = 4.219e-8
Identity = 25/80 (31.25%), Postives = 41/80 (51.25%), Query Frame = 3 
Query:  351 PYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVER 590
            P + L V  + Y T+   +RR FE YG +  + + ++    + RG+ F+ +  +RD   A    DGK +DG  + V V R
Sbjct:    6 PSRALQVDNLTYRTSPEMLRRSFEKYGDVGDVYIPRDRFTRESRGFAFVRFYDKRDAEDAMDAMDGKMLDGRELRVQVAR 85
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Sea Lamprey
Match: rbm4.2 (RNA binding motif protein 4.2 [Source:ZFIN;Acc:ZDB-GENE-030131-3019])

HSP 1 Score: 50.8322 bits (120), Expect = 1.028e-7
Identity = 26/90 (28.89%), Postives = 44/90 (48.89%), Query Frame = 3 
Query:  327 EIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSR 596
            E  +G       ++V  +  D T  ++R +FE +GP+    ++K+        Y F+  E E D  AA +  DG +  G R+LV + RS+
Sbjct:   68 EPSHGRGSSTTKMYVGNVTPDCTNVELRAKFEEFGPVAECDIVKD--------YAFVHMEREDDARAAIRALDGSEFKGRRILVQLSRSK 149
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Sea Lamprey
Match: rbmx (RNA binding motif protein X-linked [Source:NCBI gene;Acc:321860])

HSP 1 Score: 51.6026 bits (122), Expect = 1.685e-7
Identity = 27/81 (33.33%), Postives = 44/81 (54.32%), Query Frame = 3 
Query:  339 GTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            G  DP K LFV  +N DTTE  +   F  YG +  + ++K+      RG+ F+ + +  D   A ++A+GK ++G  + VD
Sbjct:    2 GEADPGK-LFVGGLNIDTTEKALEATFSKYGRVADVLLMKDRETNLSRGFAFVTFANPEDAKEAERDANGKVLEGRAMRVD 81
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Yeast
Match: SNP1 (Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of the arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001323])

HSP 1 Score: 69.707 bits (169), Expect = 8.767e-14
Identity = 52/183 (28.42%), Postives = 88/183 (48.09%), Query Frame = 3 
Query:   72 PPNLLALFAARDPITFLPPIERPKHHRKLP--YTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPN-GTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNAD---GKKIDGHRVLVDVERSRTV 602
            P ++  LF  R P+++  P + P   R+     TG+A  +           P        +R    K    + A  +++ L  WNPN  P+    DPY+T+F+ R+ YD  E ++++ F  +G I+ IR++K+ +  K +GY FI ++       A+K      G +I     +VD+ER RTV
Sbjct:    9 PDDVSRLFKPRPPLSYKRPTDYPYAKRQTNPNITGVANLLSTSLKHYMEEFPEGSPNNHLQRYEDIKLSKIKNAQLLDRRLQNWNPNVDPHIKDTDPYRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDIERGRTV 191
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Yeast
Match: HRP1 (Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483])

HSP 1 Score: 50.8322 bits (120), Expect = 2.226e-7
Identity = 24/82 (29.27%), Postives = 43/82 (52.44%), Query Frame = 3 
Query:  363 LFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNA---DGKKIDGHRVLVDVERSRT 599
            +F+  +N+DTTE  +R  F  YG +  ++++K+    + RG+ F+ +E    +    K     DGK ID  R +   E+ +T
Sbjct:  161 MFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKTQHILDGKVIDPKRAIPRDEQDKT 242
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Yeast
Match: NOP13 (Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM); relative distribution to the nucleolus increases upon DNA replication stress [Source:SGD;Acc:S000005119])

HSP 1 Score: 48.521 bits (114), Expect = 1.146e-6
Identity = 23/72 (31.94%), Postives = 40/72 (55.56%), Query Frame = 3 
Query:  351 PYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGH 566
            P + LFV  +++D T+  +R+ F+  G I  IRM     + K +G+ FI++++E     A K+   +KI G 
Sbjct:  237 PSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNALKDKSCRKIAGR 308
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Yeast
Match: PUB1 (Poly (A)+ RNA-binding protein; abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; implicated in regulation of translation; carries Q/N-rich domain at C- terminus, identified as candidate prion; human homolog Tia1 is critical for normal synaptic plasticity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004961])

HSP 1 Score: 47.7506 bits (112), Expect = 1.923e-6
Identity = 27/95 (28.42%), Postives = 51/95 (53.68%), Query Frame = 3 
Query:  297 EQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            E D ++   N I  G +   + L+V  ++   TE  +++ F+V GPI  I+++ +  N K   Y F+EY    D + A +  +GK+I+ + V ++
Sbjct:   55 ENDPSVVPANAITGGRETSDRVLYVGNLDKAITEDILKQYFQVGGPIANIKIMID-KNNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKIN 148
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Yeast
Match: NSR1 (Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation [Source:SGD;Acc:S000003391])

HSP 1 Score: 47.7506 bits (112), Expect = 2.239e-6
Identity = 22/79 (27.85%), Postives = 44/79 (55.70%), Query Frame = 3 
Query:  360 TLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSR 596
            T+FV R+++   +  +++EFE  G +   R+I      + RGY ++++E++     A +   GK+IDG  +  D+  S+
Sbjct:  169 TIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSK 247
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Nematostella
Match: EDO36859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHB5])

HSP 1 Score: 213.386 bits (542), Expect = 6.410e-67
Identity = 112/184 (60.87%), Postives = 142/184 (77.17%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLP--YTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT YLPPNLLALFA RDP+ F PP+++P   +K P  Y+G+  ++ +FEDP +TP P   ETR+EK ERKR+EK E++A ++E+ +  W+P   PN   D +KTLF+ RINYDT+ESK+RRE E+YGPIK I M+ N   +KPRGY FIEYEHERDMHAAYK+ADGKKIDG R++VDVER RTV
Sbjct:    1 MTQYLPPNLLALFAPRDPLPFAPPLDKPSWLKKTPWLYSGVGSFLHVFEDPKDTPDPTFGETREEKIERKRREKQERVAQELEEKIGSWDPQTDPNAYGDAFKTLFIGRINYDTSESKLRREMEMYGPIKHISMVYNSKASKPRGYAFIEYEHERDMHAAYKHADGKKIDGRRIVVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Nematostella
Match: EDO27750 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T8D7])

HSP 1 Score: 68.1662 bits (165), Expect = 9.629e-15
Identity = 31/57 (54.39%), Postives = 42/57 (73.68%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLP--YTGIAQYVKLFEDPSETPIP 221
            MT YLPPNLLALFA RDP+ F PP+++P   +K P  Y+G+  ++ +FEDP +TP P
Sbjct:    2 MTQYLPPNLLALFAPRDPLPFAPPLDKPSWLKKTPWLYSGVGSFLHVFEDPKDTPDP 58
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Nematostella
Match: EDO42298 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1T6])

HSP 1 Score: 57.7658 bits (138), Expect = 1.429e-9
Identity = 32/111 (28.83%), Postives = 54/111 (48.65%), Query Frame = 3 
Query:  291 KVEQDLALW-------NPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            +V  D A+W        PN+   G  D   TLF+ R++ +T    +   F  YG ++  R++++ +    RGY F+E++   D   AY+      IDG  +LV+ E  R +
Sbjct:   27 QVPHDNAVWRAMQAKYKPNKQVAG--DAGCTLFIGRLSKETRAETLVEAFSKYGEVENCRLVRDFVTGFSRGYAFVEFKERWDAKTAYREISKCCIDGQEILVEFEAGRNL 135
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Nematostella
Match: EDO44802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUS7])

HSP 1 Score: 54.299 bits (129), Expect = 9.321e-9
Identity = 26/77 (33.77%), Postives = 44/77 (57.14%), Query Frame = 3 
Query:  351 PYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            P + L V  ++  TTE  +R  FE YGP++ I+++ +    + RG+ F+ YE  +D   A +   G ++DG R+ VD
Sbjct:   93 PSRCLGVFGLSLYTTERDLRPVFEKYGPVEAIQIVYDHQTGRSRGFGFVYYEDTKDAEVAKERTTGIELDGRRIRVD 169
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Nematostella
Match: EDO44931 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUM9])

HSP 1 Score: 48.521 bits (114), Expect = 1.406e-7
Identity = 22/72 (30.56%), Postives = 39/72 (54.17%), Query Frame = 3 
Query:  363 LFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLV 578
            L+VA +  +  +  ++  F VYG +KT+ +  +  N   RG+ ++EY    +   A K+ DG +IDG  + V
Sbjct:    3 LYVAHLTRNVNKDHVQEIFSVYGRVKTVDLPTDRTNNLSRGFAYVEYVDPEECEKALKHMDGGQIDGQEIAV 74
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Medaka
Match: snrnp70 (small nuclear ribonucleoprotein U1 subunit 70 [Source:NCBI gene;Acc:101174750])

HSP 1 Score: 216.468 bits (550), Expect = 5.603e-65
Identity = 119/184 (64.67%), Postives = 143/184 (77.72%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI FLP +E+  H  H   PY+GIA +++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L LW+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I ++ N    KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPFLPQLEKLPHEKHHNQPYSGIAPFIRHFEDPRDAPPPTRAETREERLERKRREKIERRQGEVETELKLWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIYIVYNKGTGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Medaka
Match: snrnp70 (small nuclear ribonucleoprotein U1 subunit 70 [Source:NCBI gene;Acc:101174750])

HSP 1 Score: 215.698 bits (548), Expect = 6.346e-65
Identity = 119/184 (64.67%), Postives = 143/184 (77.72%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKH--HRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            MT +LPPNLLALFA RDPI FLP +E+  H  H   PY+GIA +++ FEDP + P P + ETR+E+ ERKR+EK E+   +VE +L LW+P+  PN   D +KTLFVAR+NYDTTESK+RREFEVYGPIK I ++ N    KPRGY FIEYEHERDMH+AYK+ADGKKIDG RVLVDVER RTV
Sbjct:    1 MTQFLPPNLLALFAPRDPIPFLPQLEKLPHEKHHNQPYSGIAPFIRHFEDPRDAPPPTRAETREERLERKRREKIERRQGEVETELKLWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIYIVYNKGTGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV 184
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Medaka
Match: snrnp35 (small nuclear ribonucleoprotein U11/U12 subunit 35 [Source:NCBI gene;Acc:101171854])

HSP 1 Score: 75.8702 bits (185), Expect = 1.429e-15
Identity = 38/98 (38.78%), Postives = 63/98 (64.29%), Query Frame = 3 
Query:  309 ALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTV 602
            A + PN+   G  DP  T+FVAR+N  T+E K+++ F  YG IK +R++++++    +GY FIEY+ ER +  A ++A+   +D H + VD E+ RT+
Sbjct:   37 ARYKPNKGVVG--DPLLTVFVARLNPQTSEEKLQQIFSKYGDIKRLRLVRDIVTGFSKGYGFIEYKEERSLTRARRDANKLVVDQHELFVDFEQERTL 132
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Medaka
Match: tra2a (transformer 2a [Source:NCBI gene;Acc:100049284])

HSP 1 Score: 55.8398 bits (133), Expect = 2.547e-8
Identity = 26/81 (32.10%), Postives = 45/81 (55.56%), Query Frame = 3 
Query:  339 GTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
            G  DP   L V  ++  TTE  +R  F  YGP+  + ++ +  + + RG+ F+ +E+  D   A + A+G ++DG R+ VD
Sbjct:  109 GNPDPSCCLGVFGLSLYTTERDLREVFSKYGPLSEVNIVYDQQSRRSRGFAFVYFENSEDSKEAKEQANGMELDGRRIRVD 189
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Medaka
Match: cstf2 (cleavage stimulation factor subunit 2 [Source:NCBI gene;Acc:101163985])

HSP 1 Score: 53.1434 bits (126), Expect = 3.150e-7
Identity = 22/76 (28.95%), Postives = 43/76 (56.58%), Query Frame = 3 
Query:  354 YKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVD 581
             +++FV  I Y+ TE +++  F   G + + R++ +    KP+GY F EY+ +    +A +N +G++  G  + VD
Sbjct:   28 LRSVFVGNIPYEATEEQLKDIFSEVGLVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVD 103
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Planmine SMEST
Match: SMESG000010283.1 (SMESG000010283.1)

HSP 1 Score: 346.28 bits (887), Expect = 4.277e-117
Identity = 210/210 (100.00%), Postives = 210/210 (100.00%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTVXXXXXXXXXXXXXXXXXXXXEQNSKYTT 686
            MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPKVETRDEKRERKRKEKAEQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT
Sbjct:    1 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPKVETRDEKRERKRKEKAEQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSRTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT 210
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Planmine SMEST
Match: SMESG000010283.1 (SMESG000010283.1)

HSP 1 Score: 335.88 bits (860), Expect = 7.231e-113
Identity = 210/224 (93.75%), Postives = 210/224 (93.75%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDM--------------HAAYKNADGKKIDGHRVLVDVERSRTVXXXXXXXXXXXXXXXXXXXXEQNSKYTT 686
            MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPKVETRDEKRERKRKEKAEQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDM              HAAYKNADGKKIDGHRVLVDVERSRTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT
Sbjct:    1 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPKVETRDEKRERKRKEKAEQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHGKYNLNFIEEVCTHAAYKNADGKKIDGHRVLVDVERSRTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT 224
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Planmine SMEST
Match: SMESG000010283.1 (SMESG000010283.1)

HSP 1 Score: 334.724 bits (857), Expect = 1.902e-112
Identity = 210/226 (92.92%), Postives = 210/226 (92.92%), Query Frame = 3 
Query:   57 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPXXXXXXXXXXXXXXXXXXQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDM----------------HAAYKNADGKKIDGHRVLVDVERSRTVXXXXXXXXXXXXXXXXXXXXEQNSKYTT 686
            MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPKVETRDEKRERKRKEKAEQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDM                HAAYKNADGKKIDGHRVLVDVERSRTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT
Sbjct:    1 MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPSETPIPPKVETRDEKRERKRKEKAEQIAYKVEQDLALWNPNEIPNGTKDPYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHGKYNLNFIEEVMVCTHAAYKNADGKKIDGHRVLVDVERSRTVRNWRPRRLGGGLGNTRRGPPEQNSKYTT 226
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Planmine SMEST
Match: SMESG000063924.1 (SMESG000063924.1)

HSP 1 Score: 52.373 bits (124), Expect = 2.446e-7
Identity = 29/89 (32.58%), Postives = 47/89 (52.81%), Query Frame = 3 
Query:  339 GTKD---PYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSR 596
            GT+D   P  T+ +  ++  TTE  + + F+ YG I +++++ N    + RGY FIEYE       A K   GK +DG  + +D  R +
Sbjct:  146 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGK 234
[Close]
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Planmine SMEST
Match: SMESG000063924.1 (SMESG000063924.1)

HSP 1 Score: 51.9878 bits (123), Expect = 3.078e-7
Identity = 29/89 (32.58%), Postives = 47/89 (52.81%), Query Frame = 3 
Query:  339 GTKD---PYKTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYEHERDMHAAYKNADGKKIDGHRVLVDVERSR 596
            GT+D   P  T+ +  ++  TTE  + + F+ YG I +++++ N    + RGY FIEYE       A K   GK +DG  + +D  R +
Sbjct:  146 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGK 234
The following BLAST results are available for this feature:
BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNRNP706.804e-6664.67small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
SNRNP701.151e-6564.67small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
SNRNP706.372e-5259.76small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
SNRNP706.372e-5259.76small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
SNRNP706.372e-5259.76small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnp-79.645e-6056.52RNP (RRM RNA binding domain) containing [Source:U... [more]
rnp-79.645e-6056.52RNP (RRM RNA binding domain) containing [Source:U... [more]
cpf-22.019e-832.10Cleavage and Polyadenylation Factor [Source:UniPr... [more]
cpf-22.019e-832.10Cleavage and Polyadenylation Factor [Source:UniPr... [more]
rsp-42.461e-628.57Probable splicing factor, arginine/serine-rich 4 ... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snRNP-U1-70K7.005e-7066.12gene:FBgn0016978 transcript:FBtr0331375[more]
snRNP-U1-70K7.005e-7066.12gene:FBgn0016978 transcript:FBtr0079355[more]
tra21.275e-1035.06gene:FBgn0003742 transcript:FBtr0089616[more]
tra23.597e-1035.06gene:FBgn0003742 transcript:FBtr0089615[more]
tra23.597e-1035.06gene:FBgn0003742 transcript:FBtr0089619[more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snrnp708.727e-6264.13small nuclear ribonucleoprotein 70 (U1) [Source:ZF... [more]
snrnp707.105e-5060.87small nuclear ribonucleoprotein 70 (U1) [Source:ZF... [more]
snrnp351.221e-1641.41small nuclear ribonucleoprotein 35 (U11/U12) [Sour... [more]
cirbpb1.324e-832.88cold inducible RNA binding protein b [Source:ZFIN;... [more]
cirbpb2.670e-832.88cold inducible RNA binding protein b [Source:ZFIN;... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snrnp701.567e-6463.59small nuclear ribonucleoprotein, U1 70kDa subunit ... [more]
snrnp706.548e-4856.22small nuclear ribonucleoprotein, U1 70kDa subunit ... [more]
adat13.153e-1338.38adenosine deaminase, tRNA-specific 1 [Source:Xenba... [more]
mcm3ap2.479e-830.26minichromosome maintenance complex component 3 ass... [more]
mcm3ap2.579e-830.26minichromosome maintenance complex component 3 ass... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Snrnp701.030e-6564.67small nuclear ribonucleoprotein 70 (U1) [Source:MG... [more]
Snrnp701.283e-5260.87small nuclear ribonucleoprotein 70 (U1) [Source:MG... [more]
Snrnp708.279e-3263.10small nuclear ribonucleoprotein 70 (U1) [Source:MG... [more]
Snrnp706.857e-2255.05small nuclear ribonucleoprotein 70 (U1) [Source:MG... [more]
Snrnp701.922e-2075.47small nuclear ribonucleoprotein 70 (U1) [Source:MG... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P17133|RU17_DROME7.021e-6966.12U1 small nuclear ribonucleoprotein 70 kDa OS=Droso... [more]
sp|P08621|RU17_HUMAN5.530e-6564.67U1 small nuclear ribonucleoprotein 70 kDa OS=Homo ... [more]
sp|Q62376|RU17_MOUSE7.207e-6564.67U1 small nuclear ribonucleoprotein 70 kDa OS=Mus m... [more]
sp|Q1RMR2|RU17_BOVIN1.020e-6464.67U1 small nuclear ribonucleoprotein 70 kDa OS=Bos t... [more]
sp|Q66II8|RU17_XENTR8.299e-6463.59U1 small nuclear ribonucleoprotein 70 kDa OS=Xenop... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A4V6K05.581e-10493.81SnRNP70K protein (Fragment) OS=Dugesia japonica OX... [more]
A0A0X3NZD71.323e-7671.82RRM domain-containing protein OS=Schistocephalus s... [more]
A0A0X3Q2F03.323e-7671.82RRM domain-containing protein OS=Schistocephalus s... [more]
I6T8W76.144e-7671.27U1 small nuclear ribonucleoprotein 70 kD OS=Spirom... [more]
A0A1I8IJB17.825e-7667.03RRM domain-containing protein OS=Macrostomum ligna... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000055483.11.161e-6465.22small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
ENSAMXT00000031735.11.500e-4554.89small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
snrnp353.110e-1536.19small nuclear ribonucleoprotein 35 (U11/U12) [Sour... [more]
cirbpb5.373e-930.48cold inducible RNA binding protein b [Source:ZFIN;... [more]
cirbpb6.343e-930.48cold inducible RNA binding protein b [Source:ZFIN;... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snrnp702.847e-6964.67small nuclear ribonucleoprotein 70 (U1) [Source:ZF... [more]
snrnp701.137e-6463.39small nuclear ribonucleoprotein 70 (U1) [Source:ZF... [more]
srsf2b4.219e-831.25serine and arginine rich splicing factor 2b [Sourc... [more]
rbm4.21.028e-728.89RNA binding motif protein 4.2 [Source:ZFIN;Acc:ZDB... [more]
rbmx1.685e-733.33RNA binding motif protein X-linked [Source:NCBI ge... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
SNP18.767e-1428.42Component of U1 snRNP required for mRNA splicing v... [more]
HRP12.226e-729.27Subunit of cleavage factor I; cleavage factor I is... [more]
NOP131.146e-631.94Nucleolar protein found in preribosomal complexes;... [more]
PUB11.923e-628.42Poly (A)+ RNA-binding protein; abundant mRNP-compo... [more]
NSR12.239e-627.85Nucleolar protein that binds nuclear localization ... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO368596.410e-6760.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO277509.629e-1554.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO422981.429e-928.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448029.321e-933.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449311.406e-730.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snrnp705.603e-6564.67small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
snrnp706.346e-6564.67small nuclear ribonucleoprotein U1 subunit 70 [Sou... [more]
snrnp351.429e-1538.78small nuclear ribonucleoprotein U11/U12 subunit 35... [more]
tra2a2.547e-832.10transformer 2a [Source:NCBI gene;Acc:100049284][more]
cstf23.150e-728.95cleavage stimulation factor subunit 2 [Source:NCBI... [more]
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BLAST of U1 small nuclear ribonucleoprotein 70 kDa vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000010283.14.277e-117100.00SMESG000010283.1[more]
SMESG000010283.17.231e-11393.75SMESG000010283.1[more]
SMESG000010283.11.902e-11292.92SMESG000010283.1[more]
SMESG000063924.12.446e-732.58SMESG000063924.1[more]
SMESG000063924.13.078e-732.58SMESG000063924.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030431 ID=SMED30030431|Name=U1 small nuclear ribonucleoprotein 70 kDa|organism=Schmidtea mediterranea sexual|type=transcript|length=1299bp
TGTAAACATAATTTGTTTAAGTTTTAAGGTAATTTAAATACAATCGCCAT
TAAATAATGACTGCATATTTGCCGCCAAATTTATTGGCATTATTTGCAGC
TAGAGATCCCATAACTTTTTTGCCCCCAATAGAACGTCCTAAACATCATC
GCAAACTTCCCTATACAGGTATCGCACAATATGTAAAATTGTTCGAAGAT
CCTTCTGAAACTCCAATTCCACCGAAAGTCGAAACTAGAGATGAGAAACG
TGAAAGAAAAAGAAAAGAAAAAGCAGAACAAATTGCATATAAAGTCGAAC
AGGACTTAGCTCTGTGGAATCCTAATGAAATCCCAAATGGAACAAAAGAT
CCTTATAAGACACTGTTTGTTGCTAGAATTAATTACGATACAACTGAAAG
TAAAATTAGACGGGAATTTGAAGTCTATGGTCCAATTAAAACCATTAGAA
TGATAAAGAATGTACTTAATGCAAAACCTAGAGGGTACTGTTTCATTGAA
TATGAGCATGAAAGAGACATGCATGCGGCTTATAAGAATGCGGATGGCAA
AAAAATTGACGGCCATCGAGTTCTTGTTGATGTAGAAAGATCAAGAACTG
TTCGTAATTGGAGGCCTAGGAGACTTGGCGGTGGATTAGGTAATACTAGA
AGGGGTCCACCGGAACAGAATTCAAAATACACAACTCGAGATGAACCTCG
GGAAAGGGATTCGGAAAGGCGTAAACGAAGTAGGTCGAAAGATAAAGAAA
AAGACCGTAGAGATCGAGATAGGGAAAAGGAGAGAGATAGAGATCGTGTT
AAAGAGCGAGATAAAGACCGGGATAAGGATAAGGATAGAAAAAGGGAAAG
AGATAGAGATCAGGAAACTCGCAGTGACCGAACCAAGCGGAAAAGGAGTC
GGTCGAAGGAACATAGGAAACATCGGAGCAGGTCTCGAGGTAAGTCTAAG
GATAGATCGACAGATAAATCCAAAGACAAAAAACGCAAGAAAGAAAAAGA
AATAAAGAAAGAAAAGGATAGAGAAAATGGGGTCGTTTCTGCTGCAATTC
GACAGTATGGTGAGTATGGAGCAGACATGGAATAAAATTGTTTGTATAAT
TAAAATATTCAATATTGTTCATTTTTGATTTAAGCTTTACACTTTTGATG
GAAACGAGTTATTTACGATTTTATTGGTTATCGCAATGAATTAATTTTGT
TTTGATGTTTTCTATTTTTTGTGACTTGCTAGAAATCGATGTATTTTAGA
TAAAATTTAAATCGATTTTAATTTGTCAATATTATTATTAGAGTTTTGG
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protein sequence of SMED30030431-orf-1

>SMED30030431-orf-1 ID=SMED30030431-orf-1|Name=SMED30030431-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=343bp
MTAYLPPNLLALFAARDPITFLPPIERPKHHRKLPYTGIAQYVKLFEDPS
ETPIPPKVETRDEKRERKRKEKAEQIAYKVEQDLALWNPNEIPNGTKDPY
KTLFVARINYDTTESKIRREFEVYGPIKTIRMIKNVLNAKPRGYCFIEYE
HERDMHAAYKNADGKKIDGHRVLVDVERSRTVRNWRPRRLGGGLGNTRRG
PPEQNSKYTTRDEPRERDSERRKRSRSKDKEKDRRDRDREKERDRDRVKE
RDKDRDKDKDRKRERDRDQETRSDRTKRKRSRSKEHRKHRSRSRGKSKDR
STDKSKDKKRKKEKEIKKEKDRENGVVSAAIRQYGEYGADME*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000039gamma neoblast
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR040252SNRNP70
IPR034143snRNP70_RRM
IPR035979RBD_domain_sf
IPR000504RRM_dom
IPR022023U1snRNP70_N
IPR012677Nucleotide-bd_a/b_plait_sf
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
GO:0003723RNA binding
GO:0003729mRNA binding
GO:0005515protein binding
GO:0030619U1 snRNA binding
Vocabulary: cellular component
TermDefinition
GO:0000243commitment complex
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005681spliceosomal complex
GO:0005685U1 snRNP
GO:0016607nuclear speck
GO:0030529intracellular ribonucleoprotein complex
GO:0071004U2-type prespliceosome
GO:0071011precatalytic spliceosome
GO:0071013catalytic step 2 spliceosome
Vocabulary: biological process
TermDefinition
GO:0000381regulation of alternative mRNA splicing, via spliceosome
GO:0000398mRNA splicing, via spliceosome
GO:0006397mRNA processing
GO:0007283spermatogenesis
GO:0022008neurogenesis
GO:0043484regulation of RNA splicing
GO:0048025negative regulation of mRNA splicing, via spliceosome
GO:0048477oogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 302..322
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 184..327
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 277..295
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 205..276
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 296..326
NoneNo IPR availablePANTHERPTHR13952U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDcoord: 1..322
IPR000504RNA recognition motif domainSMARTSM00360rrm1_1coord: 102..175
e-value: 1.6E-20
score: 84.2
IPR000504RNA recognition motif domainPFAMPF00076RRM_1coord: 103..172
e-value: 1.7E-18
score: 66.2
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 101..179
score: 16.602
IPR022023U1 small nuclear ribonucleoprotein of 70kDa N-terminalPFAMPF12220U1snRNP70_Ncoord: 4..91
e-value: 6.3E-25
score: 87.6
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 88..213
e-value: 4.3E-33
score: 116.2
IPR040252U1 small nuclear ribonucleoprotein 70kDaPANTHERPTHR13952:SF5U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDAcoord: 1..322
IPR034143snRNP70, RNA recognition motifCDDcd12236RRM_snRNP70coord: 100..190
e-value: 4.08328E-54
score: 170.505
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 78..202