RBR-type E3 ubiquitin transferase

Overview
NameRBR-type E3 ubiquitin transferase
Smed IDSMED30030406
Length (bp)6982
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RBR-type E3 ubiquitin transferase (SMED30030406) t-SNE clustered cells

Violin plots show distribution of expression levels for RBR-type E3 ubiquitin transferase (SMED30030406) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RBR-type E3 ubiquitin transferase (SMED30030406) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RBR-type E3 ubiquitin transferase (SMED30030406) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030406

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
anterior sideSMED30030406SMESG000049136.1 dd_Smed_v4_16493_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30030406SMESG000049136.1 dd_Smed_v4_16493_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior sideSMED30030406SMESG000019889.1 SMESG000019888.1 dd_Smed_v4_12528_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30030406SMESG000019889.1 SMESG000019888.1 dd_Smed_v4_12528_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30030406SMESG000062924.1 dd_Smed_v4_4771_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30030406SMESG000062924.1 dd_Smed_v4_4771_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
enteric muscle cellSMED30030406SMESG000049136.1 dd_Smed_v4_16493_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Human
Match: RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13432])

HSP 1 Score: 235.728 bits (600), Expect = 2.346e-63
Identity = 130/318 (40.88%), Postives = 185/318 (58.18%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G    G   G ++  S + +++   +     DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSA-SGSHMDRIGAI----RDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 580

HSP 2 Score: 56.6102 bits (135), Expect = 6.448e-7
Identity = 41/126 (32.54%), Postives = 57/126 (45.24%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC+DC + Y+  RIE  E     SC  C+     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  146 DIMTCHHRSCVDCLRQYL--RIEISESRVNISCPECTERFNPHDIRLILSDDV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKLT-CG-REGCGTEFC-YHCKQIW 258
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Human
Match: RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13432])

HSP 1 Score: 235.728 bits (600), Expect = 2.346e-63
Identity = 130/318 (40.88%), Postives = 185/318 (58.18%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G    G   G ++  S + +++   +     DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSA-SGSHMDRIGAI----RDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 580

HSP 2 Score: 56.6102 bits (135), Expect = 6.448e-7
Identity = 41/126 (32.54%), Postives = 57/126 (45.24%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC+DC + Y+  RIE  E     SC  C+     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  146 DIMTCHHRSCVDCLRQYL--RIEISESRVNISCPECTERFNPHDIRLILSDDV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKLT-CG-REGCGTEFC-YHCKQIW 258
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Human
Match: RNF19B (ring finger protein 19B [Source:HGNC Symbol;Acc:HGNC:26886])

HSP 1 Score: 226.868 bits (577), Expect = 2.696e-62
Identity = 120/263 (45.63%), Postives = 163/263 (61.98%), Query Frame = 2 
Query: 5687 DITSMGSIKTSSSRTKFNYSTEPLQTEG--EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRT 6445
            D+      +T   RTK        Q  G  +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +AIPAM+IGIP+YVGRKIH   +  K    KR +A+ GGV  + I SPVIA  +  I               GVP++LAYVY V+PI+LCR   C     N    +++F + + P T     + + +P++G S ++G T     + S T
Sbjct:  252 DMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSIGESSIEGLTSVLSTSGSPT 499

HSP 2 Score: 53.9138 bits (128), Expect = 3.423e-6
Identity = 41/123 (33.33%), Postives = 55/123 (44.72%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            SC H SC DC + Y+  R+E  E     SC  CS  +  H+I  ++           L+ + E F L R L  DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  136 SCPHRSCRDCLRHYL--RLEISESRVPISCPECSERLNPHDIRLLLADP-------PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY-GCASCPKLT-CE-REGCQTEFC-YHCKQIW 245
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Human
Match: RNF19B (ring finger protein 19B [Source:HGNC Symbol;Acc:HGNC:26886])

HSP 1 Score: 228.409 bits (581), Expect = 1.195e-61
Identity = 120/263 (45.63%), Postives = 163/263 (61.98%), Query Frame = 2 
Query: 5687 DITSMGSIKTSSSRTKFNYSTEPLQTEG--EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRT 6445
            D+      +T   RTK        Q  G  +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +AIPAM+IGIP+YVGRKIH   +  K    KR +A+ GGV  + I SPVIA  +  I               GVP++LAYVY V+PI+LCR   C     N    +++F + + P T     + + +P++G S ++G T     + S T
Sbjct:  252 DMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSIGESSIEGLTSVLSTSGSPT 499

HSP 2 Score: 55.0694 bits (131), Expect = 1.807e-6
Identity = 41/123 (33.33%), Postives = 55/123 (44.72%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            SC H SC DC + Y+  R+E  E     SC  CS  +  H+I  ++           L+ + E F L R L  DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  136 SCPHRSCRDCLRHYL--RLEISESRVPISCPECSERLNPHDIRLLLADP-------PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY-GCASCPKLT-CE-REGCQTEFC-YHCKQIW 245
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Human
Match: RNF19B (ring finger protein 19B [Source:HGNC Symbol;Acc:HGNC:26886])

HSP 1 Score: 228.024 bits (580), Expect = 1.694e-61
Identity = 120/264 (45.45%), Postives = 163/264 (61.74%), Query Frame = 2 
Query: 5687 DITSMGSIKTSSSRTKFNYSTEPLQTEG---EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRT 6445
            D+      +T   RTK        Q  G   +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +AIPAM+IGIP+YVGRKIH   +  K    KR +A+ GGV  + I SPVIA  +  I               GVP++LAYVY V+PI+LCR   C     N    +++F + + P T     + + +P++G S ++G T     + S T
Sbjct:  252 DMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSIGESSIEGLTSVLSTSGSPT 500

HSP 2 Score: 55.0694 bits (131), Expect = 1.823e-6
Identity = 41/123 (33.33%), Postives = 55/123 (44.72%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            SC H SC DC + Y+  R+E  E     SC  CS  +  H+I  ++           L+ + E F L R L  DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  136 SCPHRSCRDCLRHYL--RLEISESRVPISCPECSERLNPHDIRLLLADP-------PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY-GCASCPKLT-CE-REGCQTEFC-YHCKQIW 245
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 215.698 bits (548), Expect = 1.655e-57
Identity = 94/192 (48.96%), Postives = 137/192 (71.35%), Query Frame = 2 
Query: 5726 RTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASAC 6301
            RT F+ S +     G++K CP+C TY++KM+DGSCNHMVC +C  EFCWLC+++I+D+HYLSP+GCTFWG++ W  +K+ LWQ+GTLIGAP+ I  +A L+IP ++ G+P++VGRK+H   K K+K ++R +     VG+ +VSPV+A                +AVG+GVP++LAYVY V+P++LCR   C
Sbjct:  239 RTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHMVCTMCNAEFCWLCLKEISDLHYLSPTGCTFWGKKPWTRKKKLLWQLGTLIGAPVGIALIAGLSIPGIVFGVPVFVGRKVHQRFKYKSKTKRRFLTATCVVGSLVVSPVMA---------------VMAVGVGVPIMLAYVYGVVPLSLCRNGGC 415
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 215.698 bits (548), Expect = 1.655e-57
Identity = 94/192 (48.96%), Postives = 137/192 (71.35%), Query Frame = 2 
Query: 5726 RTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASAC 6301
            RT F+ S +     G++K CP+C TY++KM+DGSCNHMVC +C  EFCWLC+++I+D+HYLSP+GCTFWG++ W  +K+ LWQ+GTLIGAP+ I  +A L+IP ++ G+P++VGRK+H   K K+K ++R +     VG+ +VSPV+A                +AVG+GVP++LAYVY V+P++LCR   C
Sbjct:  239 RTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHMVCTMCNAEFCWLCLKEISDLHYLSPTGCTFWGKKPWTRKKKLLWQLGTLIGAPVGIALIAGLSIPGIVFGVPVFVGRKVHQRFKYKSKTKRRFLTATCVVGSLVVSPVMA---------------VMAVGVGVPIMLAYVYGVVPLSLCRNGGC 415
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 215.698 bits (548), Expect = 1.679e-57
Identity = 94/192 (48.96%), Postives = 137/192 (71.35%), Query Frame = 2 
Query: 5726 RTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASAC 6301
            RT F+ S +     G++K CP+C TY++KM+DGSCNHMVC +C  EFCWLC+++I+D+HYLSP+GCTFWG++ W  +K+ LWQ+GTLIGAP+ I  +A L+IP ++ G+P++VGRK+H   K K+K ++R +     VG+ +VSPV+A                +AVG+GVP++LAYVY V+P++LCR   C
Sbjct:  239 RTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHMVCTMCNAEFCWLCLKEISDLHYLSPTGCTFWGKKPWTRKKKLLWQLGTLIGAPVGIALIAGLSIPGIVFGVPVFVGRKVHQRFKYKSKTKRRFLTATCVVGSLVVSPVMA---------------VMAVGVGVPIMLAYVYGVVPLSLCRNGGC 415
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 215.698 bits (548), Expect = 1.679e-57
Identity = 94/192 (48.96%), Postives = 137/192 (71.35%), Query Frame = 2 
Query: 5726 RTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASAC 6301
            RT F+ S +     G++K CP+C TY++KM+DGSCNHMVC +C  EFCWLC+++I+D+HYLSP+GCTFWG++ W  +K+ LWQ+GTLIGAP+ I  +A L+IP ++ G+P++VGRK+H   K K+K ++R +     VG+ +VSPV+A                +AVG+GVP++LAYVY V+P++LCR   C
Sbjct:  239 RTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHMVCTMCNAEFCWLCLKEISDLHYLSPTGCTFWGKKPWTRKKKLLWQLGTLIGAPVGIALIAGLSIPGIVFGVPVFVGRKVHQRFKYKSKTKRRFLTATCVVGSLVVSPVMA---------------VMAVGVGVPIMLAYVYGVVPLSLCRNGGC 415
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 214.927 bits (546), Expect = 1.750e-57
Identity = 94/192 (48.96%), Postives = 137/192 (71.35%), Query Frame = 2 
Query: 5726 RTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASAC 6301
            RT F+ S +     G++K CP+C TY++KM+DGSCNHMVC +C  EFCWLC+++I+D+HYLSP+GCTFWG++ W  +K+ LWQ+GTLIGAP+ I  +A L+IP ++ G+P++VGRK+H   K K+K ++R +     VG+ +VSPV+A                +AVG+GVP++LAYVY V+P++LCR   C
Sbjct:  209 RTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHMVCTMCNAEFCWLCLKEISDLHYLSPTGCTFWGKKPWTRKKKLLWQLGTLIGAPVGIALIAGLSIPGIVFGVPVFVGRKVHQRFKYKSKTKRRFLTATCVVGSLVVSPVMA---------------VMAVGVGVPIMLAYVYGVVPLSLCRNGGC 385
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Fly
Match: CG14238 (gene:FBgn0039429 transcript:FBtr0085014)

HSP 1 Score: 152.14 bits (383), Expect = 5.697e-38
Identity = 76/177 (42.94%), Postives = 114/177 (64.41%), Query Frame = 1 
Query: 1045 ISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFE 1575
            ++P+    +IEQFL+L LI  RWLLP+  +TR QLSQLLLV IG  ADI+E F+++K+  + +   L    L +W  SL+QF +  +AT+ R+ RG  S   +      +   C  C  ++W I  +V+LQD PFL  R+++I QY + +Y N+FFTCKN+LVI+LQ++R+ V+  E
Sbjct:  144 VTPDTWTTLIEQFLMLILIVGRWLLPKGDLTRDQLSQLLLVYIGTAADIIEFFDSYKDDSIAKIGFLVFLTLGIWSWSLMQFTIVLSATRGRRPRGSGSHHKEEHTDCCQ--NCC-CGIDVWGIVLNVILQDAPFLTFRLLIIFQYKIINYMNVFFTCKNSLVIILQLYRLYVVNAE 317

HSP 2 Score: 62.3882 bits (150), Expect = 4.394e-9
Identity = 45/135 (33.33%), Postives = 69/135 (51.11%), Query Frame = 1 
Query:  433 IVKLSVVIRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQ------------YQPIKNVSNPV-NKSIYPTTQNSSAV 798
            + K+   I+A++ R +F A   LA+W VV +KS+  YW L G  +    E ++    I I+K   ++  +WF P V L+L S  P IW++E+    +            Y P  N S PV N +I+ T+ NSS V
Sbjct:    1 MAKIISTIKAILTRIIFSAHSLLAIWQVVALKSDIIYWALCGPLLLLLLEGIF---TIMIKK---TQEWRWFCPSVFLYLSSIVPAIWLLELDKVARRVGNMTSTNSTVYSP-SNYSIPVGNTTIFITSTNSSGV 128
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Zebrafish
Match: rnf19b (ring finger protein 19B [Source:NCBI gene;Acc:562396])

HSP 1 Score: 228.024 bits (580), Expect = 6.491e-62
Identity = 119/272 (43.75%), Postives = 168/272 (61.76%), Query Frame = 2 
Query: 5705 SIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRTKLNKSTELPNTSADNLH 6496
            S++T S+ +  +Y+ E   T+ +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +A+PAM+IGIP+Y+GRKIH   +  K    +R +A+ GGV  + I +PVIA  +  I               GVP++LAYVY V+PI+LCR   C           +DF + + P T     + +  P+LG S ++G   G   T     L+ +   P    D  H
Sbjct:  250 SLRTHSNHSP-SYTAEQGHTD-DIKPCPRCGAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGITLIAGIAVPAMVIGIPVYIGRKIHSHYEGKKTSHHRRNLAITGGVALSIITAPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSRGKGRGVRIDFDEDDGPITVADAWRALKSPSLGESSLEGAASGLSTTSPSEGLSVA---PGGLGDTPH 501
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Zebrafish
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-030131-9414])

HSP 1 Score: 229.95 bits (585), Expect = 3.183e-61
Identity = 139/386 (36.01%), Postives = 205/386 (53.11%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTGGNESVHSFH*NKTQNKCNLHDKLRTLALVLSEITLSKL*INIYMQIMNNKILP*YL*MSSVFILNYQNKNSYNTFVDLHYR 6922
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR + +AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D      +   +P  G+ V  DT         T + ++ + P+    ++             L  SLSAS     +   +     EN  T  +            ++ S  G+  V+ F  N+ + + ++  +  +L+     ++L  +  N   + M   IL  YL M        ++ NS    VD+  +
Sbjct:  364 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLVIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDD------ENDMNPGTGAAVT-DT---------TSVAETRQNPSIGEGSVG-----------GLTGSLSASGSHMERIGAMRDNLSENASTMALAGA--------SITGSLSGSAMVNCF--NRLEVQADVQKERCSLSGESGTVSLGTISDNASTKAMAGSILNAYLPMD-------RDGNSVEVQVDVESK 690

HSP 2 Score: 55.8398 bits (133), Expect = 8.176e-7
Identity = 41/126 (32.54%), Postives = 56/126 (44.44%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC DC + Y+  RIE  E     SC  CS     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPK+  C  +  C ++ C   C   W
Sbjct:  213 DIMTCHHRSCADCLRQYL--RIEISESRVNISCPECSERFNPHDIRMILNDRV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKIT-CG-RDGCGTEFC-YHCKQLW 325
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Zebrafish
Match: si:ch211-278j3.3 (si:ch211-278j3.3 [Source:ZFIN;Acc:ZDB-GENE-041014-147])

HSP 1 Score: 179.489 bits (454), Expect = 2.366e-46
Identity = 97/210 (46.19%), Postives = 132/210 (62.86%), Query Frame = 2 
Query: 5729 TKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKL-RKRTIAVAGGV-GAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDV 6352
            T + ++ EP   E EIK CP+C  Y++K NDGSCN M C VC C+FCWLCM++ITD+HYLSPSGCTFWG++ W+  ++ LWQ+G L+GAP+ I  +A +AIP +++GIP+Y+GRK+HG  K  N    K  + VA GV  +  VSPVIA  T  +               GVPL+L YVY V+P++LCR   C      P    +   D+
Sbjct:  263 TLYVFNEEPGDAE-EIKPCPRCGAYIMKTNDGSCNRMNCTVCACQFCWLCMQEITDVHYLSPSGCTFWGKKPWSQTRKVLWQVGMLLGAPVVISLIAGIAIPVIIVGIPIYMGRKVHGRCKKNNTSGSKHYLTVASGVMMSVFVSPVIAAITVGV---------------GVPLMLTYVYGVVPMSLCRNGWCRPQSEPPEVRNIQLEDL 456

HSP 2 Score: 57.3806 bits (137), Expect = 2.137e-7
Identity = 40/124 (32.26%), Postives = 56/124 (45.16%), Query Frame = 2 
Query: 4988 TSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +SC H +C DC + Y+  RIE  E   G +C  C   +   ++  I+           L+ R E F L R L  DP+ R CP   C Y VI     + CPKL+ C  +  C ++ C   C   W
Sbjct:  128 SSCQHRACTDCLRQYL--RIEISESRVGIACPQCPEALALPDVRAILD-------DGALLERFEEFQLRRFLAADPDTRWCPAPDCSYAVIAY-GCAECPKLS-CG-REGCETEFC-YHCRQLW 238
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Zebrafish
Match: tmem26a (transmembrane protein 26a [Source:ZFIN;Acc:ZDB-GENE-101223-2])

HSP 1 Score: 129.798 bits (325), Expect = 5.860e-32
Identity = 111/382 (29.06%), Postives = 167/382 (43.72%), Query Frame = 1 
Query:  460 ALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVKLVIITLEFTLNVDSFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSXXXXXXXXXXXXXXIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLP-RAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCE-------TELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHR 1581
            A+I R+LF+    + VW V  VK+++ YWLL    +P   E      +I   K+   +  KWFSP +LLFL S  P+IWI+E+   HQ           NK+  P  +                 +DS+   K             SI+P    SN       L  L                      E+    +   + +  + Q LL+ LI  +WLLP   G+TR +LSQLLL+ +G  ADILE        V   +  L   IL++W  S+LQF L       R          + +D      GC  C        T++W I  S+ +QDGPFL++R+++++ + V     +FF  KN LV++L ++R+ VI  + R
Sbjct:    9 AIITRSLFILVSLIGVWRVKTVKNDNMYWLLTILYLPLVVE------MIITLKRRKGQDYKWFSPAILLFLISIIPSIWILELH--HQE----------NKASDPQCR----------------KLDSWDNVK-------------SILP----SNGTMGNATLKYL----------------------ESMLTSVCANDWILALHQVLLILLILGKWLLPLGGGVTRDELSQLLLIFVGTAADILEFTSETLSDVKENNHQLVYIILAVWTWSMLQFPLHLAVVTSRP---------ENTDEPKGGDGC--CNLILSRHSTDIWNIVESLFIQDGPFLVVRLIVMIYFDVFHQMLVFFAIKNFLVVVLNLYRLIVICQDFR 306
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Zebrafish
Match: tmem26b (transmembrane protein 26b [Source:ZFIN;Acc:ZDB-GENE-080204-66])

HSP 1 Score: 96.2857 bits (238), Expect = 1.107e-20
Identity = 58/174 (33.33%), Postives = 93/174 (53.45%), Query Frame = 1 
Query: 1072 IEQFLLLCLIFARWLLPRAG-ITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCE--TELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHRA 1584
            ++Q +L+ LI  +W+LP AG +TR ++SQLLL+ +G  ADILE        V  +       IL +W  S+LQF L  +    R      SQ            G L+    T++W I  S+ LQDGPF ++R+ +++ +       +FFT KN LV++L ++R+ VI  + ++
Sbjct:  141 LQQIVLILLIVGKWMLPIAGGVTRDEMSQLLLIFVGTAADILEFISETLSDVNEESLSFVCVILVVWTLSMLQFPLHFSVVNTRAEDVSVSQ-----------DGSLYSRYRTDIWNIGGSLFLQDGPFFVVRLTVMMVFSNFHQMLVFFTLKNFLVVMLNIYRLWVIWIDSKS 303

HSP 2 Score: 63.5438 bits (153), Expect = 9.372e-10
Identity = 34/85 (40.00%), Postives = 46/85 (54.12%), Query Frame = 1 
Query:  454 IRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEI 708
            I A++ RALF+    + VW V  VK+N  YW L    +P   E+      I   ++   K  KWFSP +L FL S  PTIWI+E+
Sbjct:    6 ICAIVTRALFILVSLIGVWRVTWVKNNPLYWFLTILYLPLVVEM------ILTLRRRKGKDYKWFSPAILFFLISIIPTIWILEL 84
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Xenopus
Match: znf654 (zinc finger protein 654 [Source:Xenbase;Acc:XB-GENE-948833])

HSP 1 Score: 233.417 bits (594), Expect = 8.556e-63
Identity = 131/313 (41.85%), Postives = 178/313 (56.87%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDF---TDVETPFTQRIFDPN-----LGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C           ++F    D+    T    D         +P  G+      T S +      E   T  DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  278 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGTGKGVRIEFDDENDINVGGTNTATDATSVAEARNNPSIGEGSVGAMTGSLSASGSHLERIGTIRDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 561
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Xenopus
Match: znf654 (zinc finger protein 654 [Source:Xenbase;Acc:XB-GENE-948833])

HSP 1 Score: 233.417 bits (594), Expect = 1.270e-62
Identity = 131/313 (41.85%), Postives = 178/313 (56.87%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDF---TDVETPFTQRIFDPN-----LGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C           ++F    D+    T    D         +P  G+      T S +      E   T  DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGTGKGVRIEFDDENDINVGGTNTATDATSVAEARNNPSIGEGSVGAMTGSLSASGSHLERIGTIRDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 580
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Xenopus
Match: znf654 (zinc finger protein 654 [Source:Xenbase;Acc:XB-GENE-948833])

HSP 1 Score: 233.032 bits (593), Expect = 1.383e-62
Identity = 131/313 (41.85%), Postives = 178/313 (56.87%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDF---TDVETPFTQRIFDPN-----LGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C           ++F    D+    T    D         +P  G+      T S +      E   T  DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  287 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGTGKGVRIEFDDENDINVGGTNTATDATSVAEARNNPSIGEGSVGAMTGSLSASGSHLERIGTIRDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 570
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Xenopus
Match: znf654 (zinc finger protein 654 [Source:Xenbase;Acc:XB-GENE-948833])

HSP 1 Score: 232.646 bits (592), Expect = 1.483e-62
Identity = 131/313 (41.85%), Postives = 178/313 (56.87%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDF---TDVETPFTQRIFDPN-----LGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C           ++F    D+    T    D         +P  G+      T S +      E   T  DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  283 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGTGKGVRIEFDDENDINVGGTNTATDATSVAEARNNPSIGEGSVGAMTGSLSASGSHLERIGTIRDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 566
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Xenopus
Match: znf654 (zinc finger protein 654 [Source:Xenbase;Acc:XB-GENE-948833])

HSP 1 Score: 232.646 bits (592), Expect = 1.774e-62
Identity = 131/313 (41.85%), Postives = 178/313 (56.87%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDF---TDVETPFTQRIFDPN-----LGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C           ++F    D+    T    D         +P  G+      T S +      E   T  DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  298 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGTGKGVRIEFDDENDINVGGTNTATDATSVAEARNNPSIGEGSVGAMTGSLSASGSHLERIGTIRDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 581
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Mouse
Match: Rnf19b (ring finger protein 19B [Source:MGI Symbol;Acc:MGI:1922484])

HSP 1 Score: 225.713 bits (574), Expect = 1.008e-64
Identity = 118/253 (46.64%), Postives = 160/253 (63.24%), Query Frame = 2 
Query: 5687 DITSMGSIKTSSSRTKFNYSTEPLQTEG--EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDT 6415
            D+      +T   RTK        Q  G  +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +AIPAM+IGIP+YVGRKIH   +  K    KR +A+ GGV  + I SPVIA  +  I               GVP++LAYVY V+PI+LCR   C     N    +++F + + P T     + + +P++G S ++G T
Sbjct:   68 DMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSIGESSIEGLT 305
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Mouse
Match: Rnf19b (ring finger protein 19B [Source:MGI Symbol;Acc:MGI:1922484])

HSP 1 Score: 228.794 bits (582), Expect = 1.581e-63
Identity = 118/254 (46.46%), Postives = 160/254 (62.99%), Query Frame = 2 
Query: 5687 DITSMGSIKTSSSRTKFNYSTEPLQTEG---EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDT 6415
            D+      +T   RTK        Q  G   +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +AIPAM+IGIP+YVGRKIH   +  K    KR +A+ GGV  + I SPVIA  +  I               GVP++LAYVY V+PI+LCR   C     N    +++F + + P T     + + +P++G S ++G T
Sbjct:   68 DMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSIGESSIEGLT 306
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Mouse
Match: Rnf19a (ring finger protein 19A [Source:MGI Symbol;Acc:MGI:1353623])

HSP 1 Score: 235.728 bits (600), Expect = 1.766e-63
Identity = 123/277 (44.40%), Postives = 166/277 (59.93%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G   +G   G   T S +      +   T  DNL  T +T       +  SLS S
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIDTTSVAEARHNPSIG---EGSVGGL--TGSLSASGSHMDRIGTIRDNLSETASTMALAGASITGSLSGS 553

HSP 2 Score: 56.6102 bits (135), Expect = 4.105e-7
Identity = 41/126 (32.54%), Postives = 57/126 (45.24%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC+DC + Y+  RIE  E     SC  C+     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  146 DIMTCHHRSCVDCLRQYL--RIEISESRVNISCPECTERFNPHDIRLILSDDV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKLT-CG-REGCGTEFC-YHCKQIW 258
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Mouse
Match: Rnf19a (ring finger protein 19A [Source:MGI Symbol;Acc:MGI:1353623])

HSP 1 Score: 226.868 bits (577), Expect = 8.639e-63
Identity = 106/195 (54.36%), Postives = 140/195 (71.79%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTD 6349
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDD 476

HSP 2 Score: 55.8398 bits (133), Expect = 6.546e-7
Identity = 41/126 (32.54%), Postives = 57/126 (45.24%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC+DC + Y+  RIE  E     SC  C+     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  146 DIMTCHHRSCVDCLRQYL--RIEISESRVNISCPECTERFNPHDIRLILSDDV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKLT-CG-REGCGTEFC-YHCKQIW 258
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Mouse
Match: Rnf19b (ring finger protein 19B [Source:MGI Symbol;Acc:MGI:1922484])

HSP 1 Score: 228.794 bits (582), Expect = 6.272e-62
Identity = 120/263 (45.63%), Postives = 163/263 (61.98%), Query Frame = 2 
Query: 5687 DITSMGSIKTSSSRTKFNYSTEPLQTEG--EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRT 6445
            D+      +T   RTK        Q  G  +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +AIPAM+IGIP+YVGRKIH   +  K    KR +A+ GGV  + I SPVIA  +  I               GVP++LAYVY V+PI+LCR   C     N    +++F + + P T     + + +P++G S ++G T     + S T
Sbjct:  249 DMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSIGESSIEGLTSVLSTSGSPT 496

HSP 2 Score: 55.0694 bits (131), Expect = 1.101e-6
Identity = 41/123 (33.33%), Postives = 55/123 (44.72%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            SC H SC DC + Y+  R+E  E     SC  CS  +  H+I  ++           L+ + E F L R L  DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  133 SCPHRSCRDCLRHYL--RLEISESRVPISCPECSERLNPHDIRLLLADP-------PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY-GCASCPKLT-CE-REGCQTEFC-YHCKQIW 242
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. UniProt/SwissProt
Match: sp|Q9NV58|RN19A_HUMAN (E3 ubiquitin-protein ligase RNF19A OS=Homo sapiens OX=9606 GN=RNF19A PE=1 SV=3)

HSP 1 Score: 235.728 bits (600), Expect = 1.127e-62
Identity = 130/318 (40.88%), Postives = 185/318 (58.18%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G    G   G ++  S + +++   +     DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSA-SGSHMDRIGAI----RDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 580

HSP 2 Score: 56.6102 bits (135), Expect = 3.096e-6
Identity = 41/126 (32.54%), Postives = 57/126 (45.24%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC+DC + Y+  RIE  E     SC  C+     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  146 DIMTCHHRSCVDCLRQYL--RIEISESRVNISCPECTERFNPHDIRLILSDDV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKLT-CG-REGCGTEFC-YHCKQIW 258
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. UniProt/SwissProt
Match: sp|P50636|RN19A_MOUSE (E3 ubiquitin-protein ligase RNF19A OS=Mus musculus OX=10090 GN=Rnf19a PE=1 SV=2)

HSP 1 Score: 235.728 bits (600), Expect = 1.235e-62
Identity = 123/277 (44.40%), Postives = 166/277 (59.93%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G   +G   G   T S +      +   T  DNL  T +T       +  SLS S
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIDTTSVAEARHNPSIG---EGSVGGL--TGSLSASGSHMDRIGTIRDNLSETASTMALAGASITGSLSGS 553

HSP 2 Score: 56.6102 bits (135), Expect = 2.872e-6
Identity = 41/126 (32.54%), Postives = 57/126 (45.24%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC+DC + Y+  RIE  E     SC  C+     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  146 DIMTCHHRSCVDCLRQYL--RIEISESRVNISCPECTERFNPHDIRLILSDDV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKLT-CG-REGCGTEFC-YHCKQIW 258
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. UniProt/SwissProt
Match: sp|Q2VJ60|RN19A_PIG (E3 ubiquitin-protein ligase RNF19A OS=Sus scrofa OX=9823 GN=RNF19A PE=2 SV=1)

HSP 1 Score: 235.728 bits (600), Expect = 1.365e-62
Identity = 130/318 (40.88%), Postives = 185/318 (58.18%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G    G   G ++  S + +++   +     DNL  T +T       +  SLS S       +++  F+       ++ + V K RYS  LS  +G
Sbjct:  297 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSA-SGSHMDRIGAI----RDNLSETASTMALAGASITGSLSGS-------AMVNCFN-----RLEVQADVQKERYS--LSGESG 580

HSP 2 Score: 56.6102 bits (135), Expect = 3.149e-6
Identity = 41/123 (33.33%), Postives = 56/123 (45.53%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +C H SC+DC + Y+  RIE  E     SC  C+     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  149 TCHHRSCVDCLRQYL--RIEISESRVNISCPECTERFNPHDIRLILSDDV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKLT-CG-REGCGTEFC-YHCKQIW 258
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. UniProt/SwissProt
Match: sp|Q1L8L6|RN19B_DANRE (E3 ubiquitin-protein ligase RNF19B OS=Danio rerio OX=7955 GN=rnf19b PE=3 SV=2)

HSP 1 Score: 228.794 bits (582), Expect = 2.683e-61
Identity = 119/272 (43.75%), Postives = 168/272 (61.76%), Query Frame = 2 
Query: 5705 SIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRTKLNKSTELPNTSADNLH 6496
            S++T S+ +  +Y+ E   T+ +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +A+PAM+IGIP+Y+GRKIH   +  K    +R +A+ GGV  + I +PVIA  +  I               GVP++LAYVY V+PI+LCR   C           +DF + + P T     + +  P+LG S ++G   G   T     L+ +   P    D  H
Sbjct:  249 SLRTHSNHSP-SYTAEQGHTD-DIKPCPRCGAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGITLIAGIAVPAMVIGIPVYIGRKIHSHYEGKKTSHHRRNLAITGGVALSIITAPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSRGKGRGVRIDFDEDDGPITVADAWRALKSPSLGESSLEGAASGLSTTSPSEGLSVA---PGGLGDTPH 500
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. UniProt/SwissProt
Match: sp|A2A7Q9|RN19B_MOUSE (E3 ubiquitin-protein ligase RNF19B OS=Mus musculus OX=10090 GN=Rnf19b PE=1 SV=2)

HSP 1 Score: 228.409 bits (581), Expect = 6.224e-61
Identity = 120/264 (45.45%), Postives = 163/264 (61.74%), Query Frame = 2 
Query: 5687 DITSMGSIKTSSSRTKFNYSTEPLQTEG---EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKT-KNKLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRT 6445
            D+      +T   RTK        Q  G   +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +AIPAM+IGIP+YVGRKIH   +  K    KR +A+ GGV  + I SPVIA  +  I               GVP++LAYVY V+PI+LCR   C     N    +++F + + P T     + + +P++G S ++G T     + S T
Sbjct:  249 DMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPSIGESSIEGLTSVLSTSGSPT 497

HSP 2 Score: 55.4546 bits (132), Expect = 7.579e-6
Identity = 41/123 (33.33%), Postives = 55/123 (44.72%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            SC H SC DC + Y+  R+E  E     SC  CS  +  H+I  ++           L+ + E F L R L  DP+ R CP   C Y VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  133 SCPHRSCRDCLRHYL--RLEISESRVPISCPECSERLNPHDIRLLLADP-------PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY-GCASCPKLT-CE-REGCQTEFC-YHCKQIW 242
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. TrEMBL
Match: F7CYE5 (RBR-type E3 ubiquitin transferase OS=Ornithorhynchus anatinus OX=9258 GN=RNF19A PE=3 SV=2)

HSP 1 Score: 237.269 bits (604), Expect = 5.085e-64
Identity = 134/321 (41.74%), Postives = 185/321 (57.63%), Query Frame = 2 
Query: 5762 TEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTG 6679
            T  +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G    G   G ++  S + +++   +     DNL  T +T       +  SLS S       +++  F   N    Q D  V K RYS  LS  +G
Sbjct:    2 TADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSA-SGSHMDRIGAI----RDNLSETASTMALAGASITGSLSGS-------AMVNCF---NRLEVQAD--VQKERYS--LSGESG 288
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. TrEMBL
Match: Q4SX57 (RBR-type E3 ubiquitin transferase (Fragment) OS=Tetraodon nigroviridis OX=99883 GN=GSTENG00011114001 PE=3 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 2.002e-63
Identity = 99/195 (50.77%), Postives = 133/195 (68.21%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTD 6349
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +A+PAM+IGIP+Y+GRKIH     K   R KR +A+ GGV  + I +PV+A  +  I                VP++LAYVY V+P++LCR   C           +DF +
Sbjct:    3 DIKPCPRCGAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGITLIAGIAVPAMVIGIPVYIGRKIHAHYDLKKSSRHKRNLAITGGVALSIITAPVVAAVSVGI---------------SVPIMLAYVYGVVPVSLCRGGGCGVSRGKGRGVRIDFDE 182
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. TrEMBL
Match: G3UB45 (RBR-type E3 ubiquitin transferase OS=Loxodonta africana OX=9785 GN=RNF19A PE=3 SV=1)

HSP 1 Score: 234.572 bits (597), Expect = 4.456e-63
Identity = 121/271 (44.65%), Postives = 168/271 (61.99%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR +A+AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D         T   +   +P++G    G   G ++  S + +++   +     DNL  T +T       +  SLS S
Sbjct:  133 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDERADDPVNTTSVAEARHNPSIGEGSVGGLTGSLSA-SGSHMDRIGAI----RDNLSETASTMALAGASITGSLSGS 383
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. TrEMBL
Match: G3NBA8 (RBR-type E3 ubiquitin transferase OS=Gasterosteus aculeatus OX=69293 PE=3 SV=1)

HSP 1 Score: 235.343 bits (599), Expect = 1.382e-62
Identity = 131/306 (42.81%), Postives = 179/306 (58.50%), Query Frame = 2 
Query: 5711 KTSSSRTKFNYSTEPLQTEG---EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDT--DGFIATHSRTKLNKS-TELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVE 6604
            +  S  T  N+S   +Q +G   +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +A+PAM+IGIP+YVGRKIH   + K   R +R +A+ GGV  + I +PVIA  +  I               GVP++LAYVY V+PI+LCR   C           +DF +   P T       L SP  G++  DG ++  S T  ++  +  P T  D  H        F+     +L A   R SK S +E  + E
Sbjct:   74 RAQSLHTHSNHSPSYIQEQGPADDIKPCPRCGAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGITLIAGIAVPAMVIGIPVYVGRKIHAHYELKKASRHRRNLAITGGVALSIITAPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSRGKGRGVRIDFDEDNGPITVADAWRALKSPSLGESSLDGALSGLSTTSPSEGLSGAPGTLGDAHH--------FNTLAGGTLGA---RSSKYSRLEGQAGE 353
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. TrEMBL
Match: G3NHJ4 (RBR-type E3 ubiquitin transferase OS=Gasterosteus aculeatus OX=69293 PE=3 SV=1)

HSP 1 Score: 233.032 bits (593), Expect = 1.413e-62
Identity = 120/271 (44.28%), Postives = 167/271 (61.62%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDF------TDVETPFTQRIFDPNLGSPVK-GDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+  + KR + +AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F       D  +    R+ +P+LG     G   G   + S + + +   + +T  DN+    +T       +  SLS S
Sbjct:  151 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLVIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENENIDTTSVAETRLNNPSLGDGASVGGLTGLSLSVSGSHMERCG-MSSTQRDNMSDNASTTALAGTSITGSLSGS 405
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Cavefish
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:NCBI gene;Acc:103022576])

HSP 1 Score: 230.335 bits (586), Expect = 6.486e-62
Identity = 121/277 (43.68%), Postives = 162/277 (58.48%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR + +AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G   +G   G   T S +      E      DNL    +T       +  SLS S
Sbjct:  272 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPIGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLVIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDMNVGSGAPATDTTSVAETRNNPSIG---EGSVGGL--TGSLSASGSHMERIGAMRDNLSENASTMALAGASITGSLSGS 528

HSP 2 Score: 55.4546 bits (132), Expect = 8.530e-7
Identity = 41/126 (32.54%), Postives = 56/126 (44.44%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC DC + Y+  RIE  E     SC  CS     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPK+  C  +  C ++ C   C   W
Sbjct:  121 DIMTCHHRSCADCLRQYL--RIEISESRVNISCPECSERFNPHDIRMILGDRV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKIT-CG-RDGCGTEFC-YHCKQLW 233
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Cavefish
Match: rnf19b (ring finger protein 19B [Source:NCBI gene;Acc:103021791])

HSP 1 Score: 227.254 bits (578), Expect = 9.923e-62
Identity = 115/251 (45.82%), Postives = 163/251 (64.94%), Query Frame = 2 
Query: 5705 SIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIAT 6433
            S++T S+ +  +Y+ E   T+ +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +A+PAM+IGIP+YVGRKI+   + K   + +R +A+ GGV  + I +PVIA  +  I               GVP++LAYVY V+PI+LCR   C           +DF + + P T     + +  P+LG S ++G   G   T
Sbjct:  255 SLRTHSTHSP-SYTAEQGPTD-DIKPCPRCGAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGITLIAGIAVPAMVIGIPVYVGRKIYAHYEGKKTSQHRRNLAITGGVALSIITAPVIAAVSVGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSRGKGRGVRIDFDEDDGPITVADAWRALKSPSLGESSLEGGASGLSTT 488
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Cavefish
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:NCBI gene;Acc:103022576])

HSP 1 Score: 230.335 bits (586), Expect = 2.257e-61
Identity = 121/277 (43.68%), Postives = 162/277 (58.48%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVE-------------TPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR + +AGGV  + IVSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F D               T   +   +P++G   +G   G   T S +      E      DNL    +T       +  SLS S
Sbjct:  363 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPIGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLVIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDMNVGSGAPATDTTSVAETRNNPSIG---EGSVGGL--TGSLSASGSHMERIGAMRDNLSENASTMALAGASITGSLSGS 619

HSP 2 Score: 55.0694 bits (131), Expect = 9.465e-7
Identity = 41/126 (32.54%), Postives = 56/126 (44.44%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SC DC + Y+  RIE  E     SC  CS     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPK+  C  +  C ++ C   C   W
Sbjct:  212 DIMTCHHRSCADCLRQYL--RIEISESRVNISCPECSERFNPHDIRMILGDRV-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKIT-CG-RDGCGTEFC-YHCKQLW 324
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Cavefish
Match: si:ch211-278j3.3 (E3 ubiquitin-protein ligase RNF19B-like [Source:NCBI gene;Acc:103027424])

HSP 1 Score: 184.111 bits (466), Expect = 5.212e-48
Identity = 106/257 (41.25%), Postives = 147/257 (57.20%), Query Frame = 2 
Query: 5717 SSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGV-GAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTS 6481
            + + T + +S EP     EIK CP+C  Y++K NDGSCN M C VC C+FCWLCM++ITD+HYLSPSGCTFWG++ W+  ++ LWQ+G L+GAP+ I  +A +AIP +++GIP+Y+GRK+H   K  N    K  + VA GV  +  VSPVIA  T  +               GVPL+L YVY V+P++LCR   C      P   ++   D+ T       D   G P     D  +   S   + +   LP+TS
Sbjct:  257 ADASTLYVFSEEPGGDAEEIKACPRCGAYIMKTNDGSCNRMNCTVCACQFCWLCMQEITDVHYLSPSGCTFWGKKPWSQTRKVLWQVGMLLGAPVVISLIAGIAIPVIIVGIPIYMGRKVHSRCKKNNISGSKHYLTVASGVMTSVFVSPVIAATTVAV---------------GVPLMLTYVYGVVPMSLCRNGWCRPQTEPPETRKIQLEDLAT-----FSDHWTGEPKPPVNDAAVQEVS-VNMEEVAALPSTS 492

HSP 2 Score: 58.5362 bits (140), Expect = 7.286e-8
Identity = 53/191 (27.75%), Postives = 73/191 (38.22%), Query Frame = 2 
Query: 4988 TSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISDQNPDFLISPTNKIRSSKSDHIDKLDTQNNVPFSINEPKRNGNSINLLTRC 5560
            +SC H +C DC + Y+  RIE  E   G +C  C   +   ++  I+           L+ R E F L R L  DP+ R CP   C Y VI     + CPKL+ C  +  C ++ C   C   W                DQ  D       + R  ++ H    D      FS  EP  +   I    RC
Sbjct:  127 SSCPHRACADCLRQYL--RIEISESRVGIACPQCPEALAPPDVRAILD-------DGALLERFEEFQLRRFLASDPDTRWCPAPDCSYAVIAY-GCAECPKLS-CG-REGCDTEFC-YHCRQLWH--------------PDQTCD-------QARRQRARHTSGADASTLYVFS-EEPGGDAEEIKACPRC 282
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Cavefish
Match: ENSAMXT00000044825.1 (pep primary_assembly:Astyanax_mexicanus-2.0:6:129973:131566:1 gene:ENSAMXG00000036480.1 transcript:ENSAMXT00000044825.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 136.346 bits (342), Expect = 2.550e-35
Identity = 69/167 (41.32%), Postives = 108/167 (64.67%), Query Frame = 1 
Query: 1072 IEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILF 1572
            +EQ +L+ L+  RWL+P+  ++R QLSQLL+V +G+GADIL++F+ FKEP V+   ++ +  LSL+  +L+QF L  T T         +Q     D       C  C +E+W++  +V LQDGPFL+ R+ L+++  V +   IFFTCKN L++LL+++RIGV+ F
Sbjct:   35 LEQTMLIVLVLGRWLMPKGDMSRDQLSQLLMVYVGLGADILDIFDTFKEPEVKTKRIVIIVGLSLFSWALMQFPLVLTQTSPTTPAQAETQHPADGDRTGTSTSC--CSSEVWSLLLTVGLQDGPFLVYRLYLMIRENVLNQLMIFFTCKNILIVLLELYRIGVVHF 199
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Sea Lamprey
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-030131-9414])

HSP 1 Score: 219.55 bits (558), Expect = 3.338e-60
Identity = 106/217 (48.85%), Postives = 148/217 (68.20%), Query Frame = 2 
Query: 5705 SIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRT-IAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTD 6349
            SI+++S+    +YS +    + +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +A+PAM+IGIP+YVGRK H    + +  +  T +A+ GGV  + IVSPVIA  T  I               GVP++LAYVY V+P++LCR+  C     N     ++F D
Sbjct:  257 SIQSASA----SYSQDGAHAD-DIKPCPRCAAYIMKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGVAVPAMIIGIPVYVGRKPHTQPPSPSITKLLTHLAITGGVALSVIVSPVIAAVTVGI---------------GVPIMLAYVYGVVPVSLCRSGGCGVSTGNGRGVRIEFDD 453

HSP 2 Score: 60.4622 bits (145), Expect = 4.117e-9
Identity = 41/123 (33.33%), Postives = 57/123 (46.34%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            SC H SC+DC + Y+  RIE  E      C  C+  +  H+I  I+   T       L+ + E F L R L+ DP+ R CP   C + VI     + CPKL  C  +  C ++ C   C   W
Sbjct:  127 SCPHRSCLDCLRQYL--RIEISESRVNICCPECAERLNPHDIQRILADAT-------LMGKYEEFMLRRFLVADPDCRWCPAPDCGFAVIAT-GCASCPKLT-CE-REGCGTEFC-YHCKAMW 236
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005989.1 (pep scaffold:Pmarinus_7.0:GL479500:25802:30764:-1 gene:ENSPMAG00000005417.1 transcript:ENSPMAT00000005989.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.0922 bits (170), Expect = 2.710e-14
Identity = 44/112 (39.29%), Postives = 65/112 (58.04%), Query Frame = 1 
Query: 1255 ILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSN--IFFTCKNTLVILLQMFRIGVILFEHRA 1584
            I+++W  SL+QF L      V  + G  SQ    +  W  L       T+LWAI  SV +QDGPFL++R++L++ + V       IFFT KN LV++LQ +R+ VI  ++RA
Sbjct:   10 IMAVWTWSLMQFPLVIKDHDVTALPG--SQEQAPARGWRTL--VRVYSTDLWAIVISVFIQDGPFLVVRLLLLIHFGVLDQMQMLIFFTIKNVLVLMLQAYRLVVIYGDYRA 117
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005990.1 (pep scaffold:Pmarinus_7.0:GL479500:25802:30764:-1 gene:ENSPMAG00000005417.1 transcript:ENSPMAT00000005990.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.781 bits (164), Expect = 1.404e-13
Identity = 45/112 (40.18%), Postives = 66/112 (58.93%), Query Frame = 1 
Query: 1255 ILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSN--IFFTCKNTLVILLQMFRIGVILFEHRA 1584
            I+++W  SL+QF L     KV +   G SQ    +  W  L       T+LWAI  SV +QDGPFL++R++L++ + V       IFFT KN LV++LQ +R+ VI  ++RA
Sbjct:   10 IMAVWTWSLMQFPLV---IKVHQALPG-SQEQAPARGWRTL--VRVYSTDLWAIVISVFIQDGPFLVVRLLLLIHFGVLDQMQMLIFFTIKNVLVLMLQAYRLVVIYGDYRA 115
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005994.1 (pep scaffold:Pmarinus_7.0:GL479500:25820:30764:-1 gene:ENSPMAG00000005417.1 transcript:ENSPMAT00000005994.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.6178 bits (148), Expect = 1.776e-11
Identity = 37/106 (34.91%), Postives = 62/106 (58.49%), Query Frame = 1 
Query: 1255 ILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSN--IFFTCKNTLVILLQMFRIGVI 1566
            I+++W  SL+QF L     +++ +        +   + +R+       T+LWAI  SV +QDGPFL++R++L++ + V       IFFT KN LV++LQ +R+ VI
Sbjct:   10 IMAVWTWSLMQFPLVIKVMQLKVVCVSSVSARRFRRTLVRVYS-----TDLWAIVISVFIQDGPFLVVRLLLLIHFGVLDQMQMLIFFTIKNVLVLMLQAYRLVVI 110
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Nematostella
Match: EDO40847 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Z5])

HSP 1 Score: 127.487 bits (319), Expect = 3.022e-32
Identity = 74/169 (43.79%), Postives = 107/169 (63.31%), Query Frame = 1 
Query: 1066 RMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTAT--KVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVI 1566
            ++ E  L++ +I  RWLLPR  ITR QLS LLL  +G  ADILELFE F+EP V  +  +T ++L ++  SLLQF L  TAT  K  KIR     + K S   + L G      +++ I T + +QDGPFL+LR+VLI++Y + S  ++FFTCKN + + L M+R+ ++
Sbjct:  111 KLCELGLIIMIILGRWLLPRGEITRDQLSALLLGYVGTAADILELFEVFEEPQVGSELQITTAVLGVYSWSLLQFTLVTTATTGKDNKIR---IASNKISRREMLLHG------DIFGILTGIFMQDGPFLVLRLVLIIKYNLYSEMHLFFTCKNAIALSLLMYRLCIL 270
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Nematostella
Match: EDO47924 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKK6])

HSP 1 Score: 112.079 bits (279), Expect = 6.345e-27
Identity = 70/190 (36.84%), Postives = 106/190 (55.79%), Query Frame = 1 
Query: 1012 IFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLT-----VSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVI 1566
            IF+ + + +K    E  +  +EQ L+L L+  RWLLP+  I+R QLSQLLLV +GM ADI+E  E  KE  +R+  +L       +++  W  SL QF LT + T+         +T + ++             EL ++   +L+QDGPFLI+R++ I  Y V   +  F T KN LVI+LQ++RI V+
Sbjct:   94 IFQALGSVYKSQDDEAVLYTLEQALVLILVIGRWLLPKGSISRDQLSQLLLVYVGMAADIMEFTEIIKEDEIRKVNMLNNNHFVNAVILFWSMSLFQFTLTISGTE---------RTAQLNEY-----------IELVSLLVPMLMQDGPFLIIRLIAIAYYEVNHDTLYFLTVKNALVIMLQIYRIFVL 263
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Nematostella
Match: EDO40016 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S878])

HSP 1 Score: 107.457 bits (267), Expect = 2.037e-25
Identity = 63/174 (36.21%), Postives = 96/174 (55.17%), Query Frame = 1 
Query: 1045 ISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVI 1566
            +  E    +IEQ  LL +I  RWLLP+  +TR+ LSQLLLVN+ M ADI+E F+  K    +Q   +T++IL LW  SL+QF +  TA      + G  +T       + L G +           ++ +QDGPFL  R+ +I +Y    Y  +F T KN L++ LQ++++ V+
Sbjct:  104 VDGEVLTDLIEQTTLLMMILGRWLLPKGSLTRESLSQLLLVNLAMSADIIEFFDILKLKEAQQSHDVTLAILCLWTISLMQFPVNATA------KLGTEETAPKHRVTMDLIGTVM----------ALFMQDGPFLTFRLFMIAKYSAFGYMIVFLTVKNALLLTLQVYKLCVM 261
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Nematostella
Match: EDO32760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU47])

HSP 1 Score: 102.064 bits (253), Expect = 2.702e-23
Identity = 70/184 (38.04%), Postives = 108/184 (58.70%), Query Frame = 1 
Query: 1021 KVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQT--LKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVI 1566
            +V+ A KK+         E  +++ +I  RWLLPR  +TR QLS LLL  IGMGADILELF A  EP V  +  +T + L+L+  S+ QFC+  TAT      GG  ++  +    S +      F + +  A   ++ +QDGPFL+LR+ L++ Y V+S  +IFFT KN L +++ ++R+ ++
Sbjct:  125 QVDTAAKKVC--------ELGVVVIIIVGRWLLPRGRMTRDQLSNLLLCYIGMGADILELFAALTEPEVMHNASVTYATLALFSWSMFQFCVVATATV-----GGSEESPDITHQPSEVSTSIVDFKKKKHLA---ALFMQDGPFLLLRLSLLIGYGVSSEIHIFFTAKNALTVVIMLYRLYIL 292
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Nematostella
Match: EDO48561 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIS6])

HSP 1 Score: 95.9005 bits (237), Expect = 2.979e-21
Identity = 62/165 (37.58%), Postives = 97/165 (58.79%), Query Frame = 1 
Query: 1084 LLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADIL-ELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTAT---KVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVI 1566
            L+L +I ARWLLPR  +TR QLS LLLV +   ADI+ EL     +  +    L  VS+L  +    +QF L  TAT   +  ++    +   K+ +  +RL G      +L++I T +L+QDGPFL+LR+V++VQ+ V S  ++FFT KN + + +  +R+ V+
Sbjct:  133 LILVIIVARWLLPRGELTRDQLSTLLLVYVANAADIMGELSAEVPQAQLAAKTLYLVSVLVTYTWCFMQFTLVFTATAKSEPDEVTKQVTSKTKSQEKKLRLHG------DLYSILTIMLMQDGPFLVLRLVMLVQFRVDSEMHLFFTGKNAMALAVLFYRLLVL 291
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Medaka
Match: ENSORLT00000035803.1 (ring finger protein 19B [Source:NCBI gene;Acc:101169466])

HSP 1 Score: 233.802 bits (595), Expect = 9.682e-64
Identity = 123/273 (45.05%), Postives = 166/273 (60.81%), Query Frame = 2 
Query: 5711 KTSSSRTKFNYSTEPLQTEG---EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVGAFIV-SPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRTKLNKSTELPNTSADNLH 6496
            +  S  T  N+S    Q +G   +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +A+PAM+IGIP+Y+GRKIH   + K   R KR +A+ GGV   IV +PVIA  +  I               GVP++LAYVY V+PI+LCR   C           +DF + + P T     + +  P+LG S ++G   G   T     L+ +   P T  D  H
Sbjct:  267 RAQSLHTHSNHSPSFTQEQGPADDIKPCPRCGAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGITLIAGIAVPAMVIGIPVYIGRKIHAHYELKKSSRHKRNLAITGGVALSIVTAPVIAAVSIGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSRGKGRGVRIDFDEDDGPITVADAWRALKSPSLGESSLEGAVSGLSTTTPSEGLSVA---PGTLGDTPH 521

HSP 2 Score: 53.1434 bits (126), Expect = 4.235e-6
Identity = 35/127 (27.56%), Postives = 57/127 (44.88%), Query Frame = 2 
Query: 4955 VQMNSRECCNYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLC 5335
            V++   +      C+H SC+ C + Y+  RIE  E     SC  C+  +    + +I+  T        L+ + E F L R L  DP+ R CP   C + VI +   + CP+L     +  C ++ C
Sbjct:  133 VRLPPEQLPELLGCSHRSCLCCLRQYL--RIEITESRVQLSCPECAERLAPRQVADILDDTA-------LLEKYEEFLLRRCLASDPDCRWCPAPDCGFAVIAS-GCASCPRLV--CRREGCGAEFC 247
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Medaka
Match: ENSORLT00000003495.2 (E3 ubiquitin-protein ligase RNF19A [Source:NCBI gene;Acc:101158540])

HSP 1 Score: 231.106 bits (588), Expect = 2.233e-62
Identity = 121/279 (43.37%), Postives = 166/279 (59.50%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDF-------------TDVETPFTQRIFDPNLG--SPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKIH   + K+    KR + +AGGV  + +VSPV+A  T  I               GVP++LAYVY V+PI+LCR+  C     N     ++F             TD  +    R+ +P+LG  + V G T   ++     +   ST       DN+    +T       +  SLS S
Sbjct:  284 DIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDINKHKRNLVIAGGVTLSVLVSPVVAAVTVGI---------------GVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDNIGSGAAATDTTSVAETRLNNPSLGDAASVGGLTGLSVSGTHMERCGVST----AQRDNMSDNASTTALAGTSITGSLSGS 543

HSP 2 Score: 54.299 bits (129), Expect = 1.906e-6
Identity = 41/123 (33.33%), Postives = 55/123 (44.72%), Query Frame = 2 
Query: 4991 SCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +C H SC DC + Y+  RIE  E     SC  CS     H+I  I+           L+ + E F L R L+ +P+ R CP   C Y VI     + CPK+  C  K  C ++ C   C   W
Sbjct:  136 TCHHRSCADCLRQYL--RIEISESRVNISCPECSERFNPHDIQMILGDRA-------LMEKYEEFMLRRWLVAEPDCRWCPAPDCGYAVIAF-GCASCPKIT-CGRK-GCGTEFC-YHCKQLW 245
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Medaka
Match: ENSORLT00000009229.2 (ring finger protein 19B [Source:NCBI gene;Acc:101169466])

HSP 1 Score: 214.157 bits (544), Expect = 6.339e-60
Identity = 110/236 (46.61%), Postives = 146/236 (61.86%), Query Frame = 2 
Query: 5813 MNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLR-KRTIAVAGGVGAFIV-SPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFT-----QRIFDPNLG-SPVKGDTDGFIATHSRTKLNKSTELPNTSADNLH 6496
            MNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTLIGAP+ I  +A +A+PAM+IGIP+Y+GRKIH   + K   R KR +A+ GGV   IV +PVIA  +  I               GVP++LAYVY V+PI+LCR   C           +DF + + P T     + +  P+LG S ++G   G   T     L+ +   P T  D  H
Sbjct:    1 MNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGITLIAGIAVPAMVIGIPVYIGRKIHAHYELKKSSRHKRNLAITGGVALSIVTAPVIAAVSIGI---------------GVPIMLAYVYGVVPISLCRGGGCGVSRGKGRGVRIDFDEDDGPITVADAWRALKSPSLGESSLEGAVSGLSTTTPSEGLSVA---PGTLGDTPH 218
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Medaka
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:NCBI gene;Acc:101163998])

HSP 1 Score: 224.557 bits (571), Expect = 7.104e-60
Identity = 116/272 (42.65%), Postives = 161/272 (59.19%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTD--------VETPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKI+   + K+    KR + +AGGV  + IVSPV+A  T  I               GVP++LAYVY V+P +LCR+  C     +     ++F D          T     +   +  +P  G+      T S +      +   ++ DNL  T +T       +  SLS S
Sbjct:  281 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIYNRYEGKDMSTHKRNLVIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPFSLCRSGGCGVSAGSGKGVRIEFDDENDMNAGSAGTATDVTLVADSRNNPSIGEGSVGGMTGSLSASGSHMDHLGSNRDNLSDTASTMALAGASITGSLSGS 537

HSP 2 Score: 59.6918 bits (143), Expect = 4.404e-8
Identity = 43/126 (34.13%), Postives = 58/126 (46.03%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SCIDC + Y+  RIE  E     SC  CS     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPK+ KC  +  C ++ C   C   W
Sbjct:  130 DIMTCYHRSCIDCLRQYL--RIEILESRVNISCPECSERFNPHDICMILGDRL-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKI-KCG-REGCGTEFC-YHCKQLW 242
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Medaka
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:NCBI gene;Acc:101163998])

HSP 1 Score: 224.557 bits (571), Expect = 9.380e-60
Identity = 116/272 (42.65%), Postives = 161/272 (59.19%), Query Frame = 2 
Query: 5771 EIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKN-KLRKRTIAVAGGVG-AFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTD--------VETPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSAS 6556
            +IK CP+C  Y++KMNDGSCNHM CAVCGCEFCWLCM++I+D+HYLSPSGCTFWG++ W+ +K+ LWQ+GTL+GAP+ I  +A +AIPAM+IGIP+YVGRKI+   + K+    KR + +AGGV  + IVSPV+A  T  I               GVP++LAYVY V+P +LCR+  C     +     ++F D          T     +   +  +P  G+      T S +      +   ++ DNL  T +T       +  SLS S
Sbjct:  307 DIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIYNRYEGKDMSTHKRNLVIAGGVTLSVIVSPVVAAVTVGI---------------GVPIMLAYVYGVVPFSLCRSGGCGVSAGSGKGVRIEFDDENDMNAGSAGTATDVTLVADSRNNPSIGEGSVGGMTGSLSASGSHMDHLGSNRDNLSDTASTMALAGASITGSLSGS 563

HSP 2 Score: 59.6918 bits (143), Expect = 4.380e-8
Identity = 43/126 (34.13%), Postives = 58/126 (46.03%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFW 5359
            +  +C H SCIDC + Y+  RIE  E     SC  CS     H+I  I+           L+ + E F L R L+ DP+ R CP   C Y VI     + CPK+ KC  +  C ++ C   C   W
Sbjct:  156 DIMTCYHRSCIDCLRQYL--RIEILESRVNISCPECSERFNPHDICMILGDRL-------LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF-GCASCPKI-KCG-REGCGTEFC-YHCKQLW 268
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Planmine SMEST
Match: SMESG000062924.1 (SMESG000062924.1)

HSP 1 Score: 1139.79 bits (2947), Expect = 0.000e+0
Identity = 556/575 (96.70%), Postives = 556/575 (96.70%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISDQNPDFLISPTNKIRSSKSDHIDKLDTQNNVPFSINEPKRNGNSINLLTRCFPWRRTNRHDESKFRKLRNDKSKNETDKSPSKVPMASHTDMDDITSMGSIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTGGNESVHSFH 6706
            NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISDQNPDFLISPTNKIRSSKSDHIDKL TQNNVPFSINEPKRNGNS NLLTRCFPWRRTNRHDESKFRKLRNDKSKNETDKSPSKVPMASHTDMDDITSMGSIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIA                VAVGLGVPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSR KLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTGGNESVHSFH
Sbjct:  141 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISDQNPDFLISPTNKIRSSKSDHIDKLGTQNNVPFSINEPKRNGNSRNLLTRCFPWRRTNRHDESKFRKLRNDKSKNETDKSPSKVPMASHTDMDDITSMGSIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAA---------------VAVGLGVPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSRAKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTGGNESVHSFH 700

HSP 2 Score: 280.411 bits (716), Expect = 9.699e-80
Identity = 143/159 (89.94%), Postives = 145/159 (91.19%), Query Frame = 1 
Query: 4564 MANISNTKSIEDLTKKYINKKSDENYSSTKKKNSTMSFVERRKNVSGKSPPNPFMSRINISSFLDLMMSDKNDQSYSKSRKTNEFPLFLNQTKSTKETIQSMNSIVPDQSSGIVSDHPAESILNNKVCPVCANELPGML*LYKLCPFFMH*LLAVLCYQ 5040
            MANISNTKSIEDLTKKYINKKSDENYSSTKKKNSTMSFVERRKNVSGKSPPNPFMSRINISSFLDLMMSDKNDQSYSKSRKTNEFPLFLNQTKSTKETIQSMNSIVPDQSSGIVSDHPAE ILNNKVCPVCANELPGML  Y  C  F      + C+Q
Sbjct:    1 MANISNTKSIEDLTKKYINKKSDENYSSTKKKNSTMSFVERRKNVSGKSPPNPFMSRINISSFLDLMMSDKNDQSYSKSRKTNEFPLFLNQTKSTKETIQSMNSIVPDQSSGIVSDHPAEFILNNKVCPVCANELPGMLYNYTSCAHFS----CIDCWQ 155
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Planmine SMEST
Match: SMESG000062924.1 (SMESG000062924.1)

HSP 1 Score: 1117.84 bits (2890), Expect = 0.000e+0
Identity = 546/565 (96.64%), Postives = 546/565 (96.64%), Query Frame = 2 
Query: 4982 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISDQNPDFLISPTNKIRSSKSDHIDKLDTQNNVPFSINEPKRNGNSINLLTRCFPWRRTNRHDESKFRKLRNDKSKNETDKSPSKVPMASHTDMDDITSMGSIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAGNTNFIFRHVPFXXXXXXXXXXXPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRST 6676
            NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISDQNPDFLISPTNKIRSSKSDHIDKL TQNNVPFSINEPKRNGNS NLLTRCFPWRRTNRHDESKFRKLRNDKSKNETDKSPSKVPMASHTDMDDITSMGSIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIA                VAVGLGVPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSR KLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRST
Sbjct:  141 NYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYHNIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVIINPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISDQNPDFLISPTNKIRSSKSDHIDKLGTQNNVPFSINEPKRNGNSRNLLTRCFPWRRTNRHDESKFRKLRNDKSKNETDKSPSKVPMASHTDMDDITSMGSIKTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGCEFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIGFLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSPVIAA---------------VAVGLGVPLILAYVYVVMPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTDGFIATHSRAKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRKSKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRST 690

HSP 2 Score: 280.411 bits (716), Expect = 1.052e-79
Identity = 143/159 (89.94%), Postives = 145/159 (91.19%), Query Frame = 1 
Query: 4564 MANISNTKSIEDLTKKYINKKSDENYSSTKKKNSTMSFVERRKNVSGKSPPNPFMSRINISSFLDLMMSDKNDQSYSKSRKTNEFPLFLNQTKSTKETIQSMNSIVPDQSSGIVSDHPAESILNNKVCPVCANELPGML*LYKLCPFFMH*LLAVLCYQ 5040
            MANISNTKSIEDLTKKYINKKSDENYSSTKKKNSTMSFVERRKNVSGKSPPNPFMSRINISSFLDLMMSDKNDQSYSKSRKTNEFPLFLNQTKSTKETIQSMNSIVPDQSSGIVSDHPAE ILNNKVCPVCANELPGML  Y  C  F      + C+Q
Sbjct:    1 MANISNTKSIEDLTKKYINKKSDENYSSTKKKNSTMSFVERRKNVSGKSPPNPFMSRINISSFLDLMMSDKNDQSYSKSRKTNEFPLFLNQTKSTKETIQSMNSIVPDQSSGIVSDHPAEFILNNKVCPVCANELPGMLYNYTSCAHFS----CIDCWQ 155
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Planmine SMEST
Match: SMESG000049136.1 (SMESG000049136.1)

HSP 1 Score: 1004.2 bits (2595), Expect = 0.000e+0
Identity = 509/514 (99.03%), Postives = 511/514 (99.42%), Query Frame = 1 
Query:  202 MNVWSSDLIGSSISQWDNYNRLWIYHYGFIAVNCAQIIPALLTHWQSQIPQVVSVRFTMSNRGLKKERKFYILCWKAIVKLSVVIRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVKLVIITLEFTLNVDSFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSXXXXXXXXXXXXXXIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHRAADVEYNEELSCHKSRRSTSMFGDTASDVIQKQVSTSSLGVYPTTSIHSLFHKK 1743
            MNVWSSDLIGSSI QWDNYNRL IYHYGFIAVN AQIIPALLTHWQSQIPQVVSVRFTMSNRGLKKERKFYILCWKAIVKLSVVIRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVK+VIITLEFTLNV+SFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSEEKRMIERENRRREIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHRAADVEYNEELSCHKSRRSTSMFGDTASDVIQKQVSTSSLGVYPTTSIHSLFHKK
Sbjct:    1 MNVWSSDLIGSSIIQWDNYNRLSIYHYGFIAVNSAQIIPALLTHWQSQIPQVVSVRFTMSNRGLKKERKFYILCWKAIVKLSVVIRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVKMVIITLEFTLNVESFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSEEKRMIERENRRREIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHRAADVEYNEELSCHKSRRSTSMFGDTASDVIQKQVSTSSLGVYPTTSIHSLFHKK 514
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BLAST of RBR-type E3 ubiquitin transferase vs. Planmine SMEST
Match: SMESG000049136.1 (SMESG000049136.1)

HSP 1 Score: 891.338 bits (2302), Expect = 0.000e+0
Identity = 454/460 (98.70%), Postives = 458/460 (99.57%), Query Frame = 1 
Query:  364 VRFTMSNRGLKKERKFYILCWKAIVKLSVVIRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVKLVIITLEFTLNVDSFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSXXXXXXXXXXXXXXIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHRAADVEYNEELSCHKSRRSTSMFGDTASDVIQKQVSTSSLGVYPTTSIHSLFHKK 1743
            + + MSNRGLKKERKFYILCWKAIVKLSVVIRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVK+VIITLEFTLNV+SFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSEEKRMIERENRRREIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHRAADVEYNEELSCHKSRRSTSMFGDTASDVIQKQVSTSSLGVYPTTSIHSLFHKK
Sbjct:   14 INYIMSNRGLKKERKFYILCWKAIVKLSVVIRALIVRALFVAFIFLAVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVKMVIITLEFTLNVESFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSEEKRMIERENRRREIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVILFEHRAADVEYNEELSCHKSRRSTSMFGDTASDVIQKQVSTSSLGVYPTTSIHSLFHKK 473
[Close]
BLAST of RBR-type E3 ubiquitin transferase vs. Planmine SMEST
Match: SMESG000079787.1 (SMESG000079787.1)

HSP 1 Score: 228.409 bits (581), Expect = 8.032e-65
Identity = 154/368 (41.85%), Postives = 197/368 (53.53%), Query Frame = 1 
Query:  610 IEKKDSSKIGKWFSPVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKS---------IYPTTQNSSAVKLV-----------IITLEFTL-------------------------NVDSFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVLNVLASSXXXXXXXXXXXXXXIFEKVENAWKKISPENRVRMIEQFLLLCLIFARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTVSILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKT---SDSWIRLPGCLFCETELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMFRIGVIL 1569
            ++ K  SK+ KWFSPVV LFL  ACP IWI+E++I         + N  ++          + PTT  S+ +  V             TL  TL                         NV   +     S  +  P  + S I  + +SNR  K +  +VL                   +K+E+    +    R  ++EQ LLL LI  RWLLPR GITR QLSQLLLVNIGM ADILELFEA KE VVR   +L + IL LWQ SL QF LTKT TK RK+R G+ +   T   +++ +++  C+ C TELWAI+TS+LLQD PF  LR+ LIV + V SYSNIFFTCKN+LVILLQ+FR  VIL
Sbjct:    1 MDVKPKSKVNKWFSPVVFLFLMCACPPIWIMELTIASNVTGHSEILNLTSREATISHFRPQLLPTTFQSANLTQVQSTKSPISVVSTSTLNITLSDIIENNSTNLTSVSYGENSTLNETNVPMSKNVSEISTVLQQPTTVISKINLSTNSNRVIKQKGTDVL-------------------KKIESMLAYLDIPYRTTILEQVLLLTLIICRWLLPRGGITRDQLSQLLLVNIGMAADILELFEALKEKVVRHHLILNIIILVLWQMSLFQFSLTKTVTKARKVRLGYFEDYSTKSNTENNLQITNCICCRTELWAIATSLLLQDIPFFCLRITLIVDFDVLSYSNIFFTCKNSLVILLQLFRSYVIL 349
The following BLAST results are available for this feature:
BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RNF19A2.346e-6340.88ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
RNF19A2.346e-6340.88ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
RNF19B2.696e-6245.63ring finger protein 19B [Source:HGNC Symbol;Acc:HG... [more]
RNF19B1.195e-6145.63ring finger protein 19B [Source:HGNC Symbol;Acc:HG... [more]
RNF19B1.694e-6145.45ring finger protein 19B [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
C17H11.61.655e-5748.96RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.61.655e-5748.96RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.61.679e-5748.96RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.61.679e-5748.96RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.61.750e-5748.96RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG142385.697e-3842.94gene:FBgn0039429 transcript:FBtr0085014[more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf19b6.491e-6243.75ring finger protein 19B [Source:NCBI gene;Acc:5623... [more]
rnf19a3.183e-6136.01ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
si:ch211-278j3.32.366e-4646.19si:ch211-278j3.3 [Source:ZFIN;Acc:ZDB-GENE-041014-... [more]
tmem26a5.860e-3229.06transmembrane protein 26a [Source:ZFIN;Acc:ZDB-GEN... [more]
tmem26b1.107e-2033.33transmembrane protein 26b [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
znf6548.556e-6341.85zinc finger protein 654 [Source:Xenbase;Acc:XB-GEN... [more]
znf6541.270e-6241.85zinc finger protein 654 [Source:Xenbase;Acc:XB-GEN... [more]
znf6541.383e-6241.85zinc finger protein 654 [Source:Xenbase;Acc:XB-GEN... [more]
znf6541.483e-6241.85zinc finger protein 654 [Source:Xenbase;Acc:XB-GEN... [more]
znf6541.774e-6241.85zinc finger protein 654 [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rnf19b1.008e-6446.64ring finger protein 19B [Source:MGI Symbol;Acc:MGI... [more]
Rnf19b1.581e-6346.46ring finger protein 19B [Source:MGI Symbol;Acc:MGI... [more]
Rnf19a1.766e-6344.40ring finger protein 19A [Source:MGI Symbol;Acc:MGI... [more]
Rnf19a8.639e-6354.36ring finger protein 19A [Source:MGI Symbol;Acc:MGI... [more]
Rnf19b6.272e-6245.63ring finger protein 19B [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9NV58|RN19A_HUMAN1.127e-6240.88E3 ubiquitin-protein ligase RNF19A OS=Homo sapiens... [more]
sp|P50636|RN19A_MOUSE1.235e-6244.40E3 ubiquitin-protein ligase RNF19A OS=Mus musculus... [more]
sp|Q2VJ60|RN19A_PIG1.365e-6240.88E3 ubiquitin-protein ligase RNF19A OS=Sus scrofa O... [more]
sp|Q1L8L6|RN19B_DANRE2.683e-6143.75E3 ubiquitin-protein ligase RNF19B OS=Danio rerio ... [more]
sp|A2A7Q9|RN19B_MOUSE6.224e-6145.45E3 ubiquitin-protein ligase RNF19B OS=Mus musculus... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
F7CYE55.085e-6441.74RBR-type E3 ubiquitin transferase OS=Ornithorhynch... [more]
Q4SX572.002e-6350.77RBR-type E3 ubiquitin transferase (Fragment) OS=Te... [more]
G3UB454.456e-6344.65RBR-type E3 ubiquitin transferase OS=Loxodonta afr... [more]
G3NBA81.382e-6242.81RBR-type E3 ubiquitin transferase OS=Gasterosteus ... [more]
G3NHJ41.413e-6244.28RBR-type E3 ubiquitin transferase OS=Gasterosteus ... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf19a6.486e-6243.68ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
rnf19b9.923e-6245.82ring finger protein 19B [Source:NCBI gene;Acc:1030... [more]
rnf19a2.257e-6143.68ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
si:ch211-278j3.35.212e-4841.25E3 ubiquitin-protein ligase RNF19B-like [Source:NC... [more]
ENSAMXT00000044825.12.550e-3541.32pep primary_assembly:Astyanax_mexicanus-2.0:6:1299... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
rnf19a3.338e-6048.85ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
ENSPMAT00000005989.12.710e-1439.29pep scaffold:Pmarinus_7.0:GL479500:25802:30764:-1 ... [more]
ENSPMAT00000005990.11.404e-1340.18pep scaffold:Pmarinus_7.0:GL479500:25802:30764:-1 ... [more]
ENSPMAT00000005994.11.776e-1134.91pep scaffold:Pmarinus_7.0:GL479500:25820:30764:-1 ... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO408473.022e-3243.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO479246.345e-2736.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO400162.037e-2536.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO327602.702e-2338.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO485612.979e-2137.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000035803.19.682e-6445.05ring finger protein 19B [Source:NCBI gene;Acc:1011... [more]
ENSORLT00000003495.22.233e-6243.37E3 ubiquitin-protein ligase RNF19A [Source:NCBI ge... [more]
ENSORLT00000009229.26.339e-6046.61ring finger protein 19B [Source:NCBI gene;Acc:1011... [more]
rnf19a7.104e-6042.65ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
rnf19a9.380e-6042.65ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
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BLAST of RBR-type E3 ubiquitin transferase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000062924.19.699e-8096.70SMESG000062924.1[more]
SMESG000062924.11.052e-7996.64SMESG000062924.1[more]
SMESG000049136.10.000e+099.03SMESG000049136.1[more]
SMESG000049136.10.000e+098.70SMESG000049136.1[more]
SMESG000079787.18.032e-6541.85SMESG000079787.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030406 ID=SMED30030406|Name=RBR-type E3 ubiquitin transferase|organism=Schmidtea mediterranea sexual|type=transcript|length=6982bp
CTTTCATTACTCTTATAACAGTTTACCAAGCCTTTCTTGGCTTTCATCAA
TTTTCTCATAATGTATATATATATATATAGAAAAATACGATCGCAATAAT
CTCAAACCAATTATAAGAAATTAATTTATTAATTATTTAATTAATTAACG
GATTATCGAGAACAAATACAAACAAAAGTCCAAGTATAGTAAAATGAATA
TATGAATGTCTGGTCTAGCGATTTGATTGGTTCTTCGATCAGCCAATGGG
ATAATTATAATCGATTGTGGATTTATCATTATGGATTTATTGCCGTGAAC
TGCGCCCAGATTATCCCAGCACTCCTCACTCACTGGCAATCACAAATTCC
TCAAGTTGTCTCCGTTAGATTCACAATGTCGAACCGCGGCCTGAAGAAGG
AAAGGAAGTTTTATATTTTATGTTGGAAGGCGATTGTGAAGCTATCTGTC
GTCATAAGAGCTTTGATTGTTCGAGCACTGTTTGTAGCATTCATATTTCT
TGCCGTATGGAATGTGGTAATTGTCAAATCCAATGACTTCTATTGGCTGC
TGCTTGGATGCGCGATTCCGTTCGCCGCTGAGGTTCTCTATGCTTGCAAA
GTCATTTTTATCGAGAAAAAGGATTCTTCAAAAATCGGGAAATGGTTTTC
TCCTGTGGTTTTGTTGTTTCTCTGCTCAGCCTGTCCGACAATATGGATCA
TAGAAATATCCATTTGGCACCAATACCAACCTATAAAGAATGTTTCTAAC
CCTGTGAATAAAAGTATTTATCCGACTACTCAAAACTCTTCGGCAGTCAA
ATTGGTCATTATTACGCTTGAATTCACACTCAATGTGGATAGCTTCCAAC
AAAGAAAACCGACGTCCCCTGCAATTACAACTCCGGAGTTTTTAACTTCC
ATCATTCCTTCTACATTTCATTCGAACAGAAGAAAGAAAACTCGGGTCTT
GAATGTTCTGGCATCATCGGAAGAAAAGCGAATGATCGAGAGAGAAAACC
GAAGAAGAGAAATATTTGAAAAGGTTGAGAATGCATGGAAAAAGATTTCT
CCAGAAAATCGAGTTCGGATGATTGAGCAATTCCTTCTGTTGTGTTTGAT
CTTTGCTCGCTGGCTTCTGCCACGGGCGGGCATTACTAGGCAACAGTTAT
CCCAACTATTGCTAGTAAACATTGGAATGGGGGCCGATATTCTAGAGCTG
TTTGAGGCATTCAAGGAGCCAGTTGTCAGGCAGGATTTCCTGCTAACAGT
GTCTATTCTCAGTCTCTGGCAAGCGAGTTTATTGCAGTTCTGCTTGACAA
AAACTGCGACAAAAGTCAGAAAGATTCGAGGCGGTTTTTCACAAACTTTG
AAAACATCTGATTCCTGGATCCGTTTGCCAGGCTGTTTATTTTGTGAAAC
TGAATTATGGGCAATCAGCACCAGTGTCCTTCTACAGGATGGACCTTTTC
TTATTCTCAGAGTCGTTCTTATCGTTCAATATTACGTTGCGAGTTATTCG
AATATATTTTTCACCTGCAAAAATACTCTTGTGATACTTCTACAAATGTT
CCGAATCGGAGTGATTCTGTTTGAGCACAGAGCCGCAGATGTCGAGTATA
ATGAAGAGCTGAGTTGTCACAAATCGAGAAGGTCAACAAGCATGTTTGGT
GATACCGCTTCAGACGTTATTCAGAAACAAGTTTCTACTAGTAGTCTTGG
AGTTTATCCAACTACCTCAATACATAGCTTATTCCACAAAAAGAATAATA
ATAATAATAACAATAACTCCCCGAACTCTGGTGTCATTCTGGACGTGCTG
GGGGCCCTAGCTACAGTGAGGAGGTATTGTGAGGCCAATGGACTCGAGCT
AGGTTTGCTGCAGCAGCTTGAGAAGCAGATTGCCGTCAGCGAATTGCACA
GATTGAGCCAGTGATCCTCATCTCCATTCTTATCATTATTTTTGAGTTTG
TGAAAATAAATTTCTCTATCATTTTCACCGGCGAGTTCTGAGGAGCAAGT
CGCATTGTTATGAACTGAAAGTCTGAGAATATCACCATAAATTATATCAA
CATTAATTCATATTTATATAGTTGTTGATTCCTTTCCAATGTTTGGCACC
ATACACAAGCCGTATTGCCCTGTTTCTGCGGTTTAGGTGGGGGGGGGGGG
CAGTGCACGATTCTCGAGCCTTCGGTCGGTTTATTGAGACAAAGGCAAAA
ATAGAAATTTAAATCAAAATTCTCAAATCATAAATTGTGTGCAGCACAAA
TTTATTGAATAAAAATATTGTTTGCACAGTTTATCCGCTTTCAGTTCATA
TCAGCAACTGATTTCCAAATCGAGCACTTATGTATGCCACTTGTCGCTTT
TTATCTTTCCCTTATTTTATTATCTATTATTATTATTATTATTTCTATTA
TTCATTATTCATTATTGTTAATATATCTTGGTTCTAAGTTCATGTTCATG
ACCATGATACCAACGTTTTGTGGCTCTTATGACATTTTGATCTTTTATCA
ATTAATATTTTCCTTGTACTGAAATACATTTATTTTAATATCAACTTTCT
TTATGGTTAAATACTTTTAAAGTATTTTCGTATAACATTAGTTCATATTT
TCATGCTTACAGGATGTGAGAGAAACTACGATTTAAAGACTAAGGAAATG
TTATTTAAATTTAAATTAACGTTTGTTTTCATGAAATTTTTATTGTAATG
ATATAAATCATAATAAATAACTTTTGTTTTCATTAGGACTATATTAATCA
AAGTTAATTGTGCTGTCTAACACTAATCTGATCTTTTGAAATCATGAAAA
TAAACCAAAAACCGATCAAATGTGAACAAAAAAAATTATTTTTTTACTAA
TATGATAATTTATCATAAATAACAGTTGAATTTCTTTCATTTTTTGGAAA
TAACATATTTTTATTAGTTGGAAAAATTCGGCTAACATTAAAAGAAAGAA
AATCACTATTACTTTTATATTAAAGAATTCAAGCAAAGAAGGAAATAAGT
GGAGAAATTTTTATCCATGTTTCTAATTGCGTGATTTACGCATGAAAATA
ATTTAATAAGCGTTCTCGACTAAATACATCTTTTATAGCATTAATTTATA
TGATAAATGATATCTTATTTTATTATTCACTATTTAATAAGTTAGTCGTA
TAAACGAGCTGTTCATGTGCTTACTTATAAACATTTGTTTGACAAGATTA
ATGCGTTTATTGTTTTAATTTATTTTAATGTAAATTAAAACAAGCTTTCT
AGTTTTCTAATCATCTTCGAATTTTCTAGTTATATAAATTATCAAAATTC
AAATAACTTGATATATAATGTTAAATTTTATTTGAGGAAAATATATTAAA
TTTCAATTTATCATGAATTTTGGTGTGGGCAATTATAATAGATTAAATTA
AAAAATAATAAGATTATGGAATGTATTTTAAAATTATTTCTAAATTTGTG
AAAGGAATAAATTTTCTCACTTGTGAACAGAATGAGTATTTCTGTTGCGT
GTTTAAATAGGCGTCAGTGAATGAATCCGTTTAATTGATGTGGAAAGATT
TTCCTTCAAATCCATTTTTAAGAAAAAACAATTTGCTATGTGATCTAAAT
TTGCTTTGATTTATTTTTTGATACAATGTATTTTCCAAAGTTTCTAATTT
AAAACGATCACTTTTACATTTCAACTACATTTGTTGGTATCATGTAAGTG
TATCATAAGTGTGGGCCAGTCATTTTTGGAGTCATTTGGGTTCATATTTT
TCATTTAGAGATTTTAAATGCTTCCTGTTTGCATAAAAAGCGAAATATTA
AATTTATTTAAAATGAAATTATAATTATTTTTTGGAACTGTCGAGTTTTT
TATCTATGATTATTTGTTTTATTAAGCCATATACGGTGAAATGTAAATTT
CGCGCTTGGTCAAACACTCACCTGACGATGTGTGTTTATGTGGGCATAAA
GTGTTTTTCTGTATACAATCTTAATGTCATTTTATTTATTTAAAATCCTA
ATTCAGTTACAGCATTTATTATTTCCATATCAGTTTTCAATTATAATAAT
AATCCCAATCAATTTCTAACATAAAATTTAATTTGTGTTTGTCTGTATCT
AACAATGGCAGGCGACAACATTAAAAACATTGTTATGATGCAATTATATT
AAATAAAACAAATAATTAGTTGATACAACTAGTGTTAATGTGAAATTTTA
ATTTTTTTGTTATATACTGTACATTCTTACATTCTTACATTCTTACAAAA
TATTTCATAAAGCTTTATGTATAAAAGCCATCTATTTATTAGCTTTATTT
ATTATAAGTTATATTAAAATGTATGAAAATTCTAATTTAGTAAGACATGA
AATATAATTTATATAATTATAATAATCATTCTGTATAACTAATTTTATAA
CTAAAATTGTTGATCATCTCTCAATTTTCACGGATGCGCATATCAATAAC
TTAATAGAATTAATTTTTGAGAATTAAATAAGAACTTAAATCTAATCTTT
TTATAATTAATATTAATAAATTTTAATTTTTTTAGTTTTAATAATCAAAT
GACATTATAAACTATGGCAAACATAAGCAACACCAAATCAATTGAAGATT
TAACGAAAAAATATATTAACAAGAAATCCGATGAAAATTATAGTTCAACG
AAAAAGAAAAACTCTACTATGAGCTTTGTGGAAAGACGCAAAAATGTTTC
CGGAAAATCACCACCAAACCCTTTTATGTCCCGTATTAATATATCTTCAT
TTTTGGATTTAATGATGTCAGATAAAAACGATCAATCTTATTCTAAAAGT
AGAAAGACAAATGAATTTCCGTTGTTTTTGAACCAAACGAAATCTACAAA
AGAAACAATTCAATCCATGAATAGCATAGTGCCCGATCAGAGCTCAGGAA
TTGTCTCTGATCATCCTGCTGAATCCATTCTAAATAACAAAGTCTGCCCT
GTCTGTGCAAATGAACTCCCGGGAATGTTGTAATTATACAAGTTGTGCCC
ATTTTTCATGCATTGATTGCTGGCAGTGTTATGTTATCAGTCGAATTGAG
AACTATGAAATCGGGTTTGGATTTTCTTGTCTAACTTGTAGCAGTGAGAT
ACCCTATCACAATATTATTGAGATTATCAAGCAAACAACTGATGAAGAGT
ATTCTGCCAAACTTATTTTCAGATTGGAAAATTTCTATCTAGAAAGATCT
CTTCTGCAAGATCCAAATTTCAGGCGTTGTCCAAATCGAGGATGCGAGTA
TGGTGTCATTATAAATCCCGATTTTTCTGGTTGTCCAAAATTAGCCAAAT
GTTCTTTAAAACCGAATTGTTCTAGTCAGCTTTGTGGTGGTCAGTGTTCA
TTATTTTGGAAATTGACAGCTTCTCATGATTGTAAATATGAATCAAATGA
AATATCAGATCAAAATCCAGATTTCTTAATTTCTCCTACAAATAAAATAA
GATCTTCGAAATCAGATCACATTGACAAATTAGACACTCAAAATAATGTT
CCCTTTTCAATCAATGAGCCAAAAAGAAATGGAAATTCTATAAACTTGCT
TACTCGTTGCTTTCCGTGGAGACGGACCAATCGTCACGATGAATCAAAAT
TTCGAAAGTTACGAAATGACAAAAGTAAGAATGAAACTGATAAATCCCCA
TCCAAAGTGCCAATGGCTTCTCATACTGATATGGATGATATCACATCAAT
GGGATCCATAAAAACCTCTTCTAGCAGAACAAAATTTAATTATTCAACTG
AACCGTTACAAACCGAAGGTGAAATAAAAATGTGCCCAAAATGTCACACA
TATGTGCTGAAAATGAATGATGGGAGCTGTAATCATATGGTCTGTGCCGT
TTGTGGCTGTGAATTTTGCTGGCTTTGTATGAGGCAAATAACCGATATGC
ATTATTTAAGTCCATCGGGGTGCACTTTTTGGGGAAGAAGACAATGGAAT
GTGGAGAAACGTGCTCTTTGGCAAATGGGGACATTGATTGGTGCTCCATT
AGCCATTGGGTTTTTAGCTGCTTTAGCAATACCCGCAATGCTTATTGGAA
TTCCGCTTTATGTCGGTCGCAAGATTCATGGTGCTTTAAAAACTAAAAAC
AAACTAAGAAAAAGAACAATAGCTGTAGCTGGTGGTGTTGGAGCATTCAT
TGTTTCTCCTGTAATTGCAGGTAACACAAATTTCATTTTCCGACATGTCC
CATTTGTTTTATAAGCCGTGGCAGTTGGATTAGGTGTTCCTTTGATTTTG
GCCTATGTTTATGTCGTTATGCCTATTGCATTATGCAGAGCATCAGCATG
CAGTTGTGATGAAAATAATCCCCCTCAAGAAGAAGTCGATTTCACTGATG
TTGAAACTCCTTTCACACAACGAATTTTCGACCCGAATTTAGGCTCCCCA
GTCAAAGGTGACACTGATGGATTTATTGCAACACATTCAAGAACTAAACT
CAATAAATCTACAGAACTACCAAACACTTCAGCAGATAATTTGCATCGAA
CAGTCGCTACAAAATTCAAATTCGATGTGAAGCTGCGGAATTCTCTATCA
GCGTCTAAAAAGCGGAAATCTAAAACCAGCCTAATTGAATCATTTTCTGT
GGAAAATTTGCGGACTTGTCAAATCGATTCAGTAGTGTATAAAACTCGAT
ACAGTGATCCGTTAAGTAGATCGACAGGTGGGAACGAAAGTGTGCATTCG
TTTCATTAAAACAAAACACAAAATAAATGCAACCTTCATGATAAACTCAG
AACTCTTGCCTTAGTTTTGAGCGAGATTACGCTTTCTAAATTATAGATAA
ATATTTATATGCAGATAATGAATAATAAAATTCTGCCGTAGTATCTGTAA
ATGAGTTCTGTTTTTATTTTAAATTATCAAAACAAAAATTCATACAACAC
ATTCGTAGATTTACATTATCGCTCTTTAATTGATGCTAGACAGCGTGAAT
CGCCGAGTCCTCATCTATTCATATCTCAAGGC
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protein sequence of SMED30030406-orf-1

>SMED30030406-orf-1 ID=SMED30030406-orf-1|Name=SMED30030406-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=418bp
MNSRECCNYTSCAHFSCIDCWQCYVISRIENYEIGFGFSCLTCSSEIPYH
NIIEIIKQTTDEEYSAKLIFRLENFYLERSLLQDPNFRRCPNRGCEYGVI
INPDFSGCPKLAKCSLKPNCSSQLCGGQCSLFWKLTASHDCKYESNEISD
QNPDFLISPTNKIRSSKSDHIDKLDTQNNVPFSINEPKRNGNSINLLTRC
FPWRRTNRHDESKFRKLRNDKSKNETDKSPSKVPMASHTDMDDITSMGSI
KTSSSRTKFNYSTEPLQTEGEIKMCPKCHTYVLKMNDGSCNHMVCAVCGC
EFCWLCMRQITDMHYLSPSGCTFWGRRQWNVEKRALWQMGTLIGAPLAIG
FLAALAIPAMLIGIPLYVGRKIHGALKTKNKLRKRTIAVAGGVGAFIVSP
VIAGNTNFIFRHVPFVL*
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protein sequence of SMED30030406-orf-2

>SMED30030406-orf-2 ID=SMED30030406-orf-2|Name=SMED30030406-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=571bp
MNVWSSDLIGSSISQWDNYNRLWIYHYGFIAVNCAQIIPALLTHWQSQIP
QVVSVRFTMSNRGLKKERKFYILCWKAIVKLSVVIRALIVRALFVAFIFL
AVWNVVIVKSNDFYWLLLGCAIPFAAEVLYACKVIFIEKKDSSKIGKWFS
PVVLLFLCSACPTIWIIEISIWHQYQPIKNVSNPVNKSIYPTTQNSSAVK
LVIITLEFTLNVDSFQQRKPTSPAITTPEFLTSIIPSTFHSNRRKKTRVL
NVLASSEEKRMIERENRRREIFEKVENAWKKISPENRVRMIEQFLLLCLI
FARWLLPRAGITRQQLSQLLLVNIGMGADILELFEAFKEPVVRQDFLLTV
SILSLWQASLLQFCLTKTATKVRKIRGGFSQTLKTSDSWIRLPGCLFCET
ELWAISTSVLLQDGPFLILRVVLIVQYYVASYSNIFFTCKNTLVILLQMF
RIGVILFEHRAADVEYNEELSCHKSRRSTSMFGDTASDVIQKQVSTSSLG
VYPTTSIHSLFHKKNNNNNNNNSPNSGVILDVLGALATVRRYCEANGLEL
GLLQQLEKQIAVSELHRLSQ*
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protein sequence of SMED30030406-orf-3

>SMED30030406-orf-3 ID=SMED30030406-orf-3|Name=SMED30030406-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=140bp
MANISNTKSIEDLTKKYINKKSDENYSSTKKKNSTMSFVERRKNVSGKSP
PNPFMSRINISSFLDLMMSDKNDQSYSKSRKTNEFPLFLNQTKSTKETIQ
SMNSIVPDQSSGIVSDHPAESILNNKVCPVCANELPGML*
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protein sequence of SMED30030406-orf-4

>SMED30030406-orf-4 ID=SMED30030406-orf-4|Name=SMED30030406-orf-4|organism=Schmidtea mediterranea sexual|type=polypeptide|length=147bp
MPIALCRASACSCDENNPPQEEVDFTDVETPFTQRIFDPNLGSPVKGDTD
GFIATHSRTKLNKSTELPNTSADNLHRTVATKFKFDVKLRNSLSASKKRK
SKTSLIESFSVENLRTCQIDSVVYKTRYSDPLSRSTGGNESVHSFH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000101muscle cell
PLANA:0000140anterior region of the whole animal
PLANA:0000142posterior region of the whole animal
PLANA:0002056medial muscle cell
PLANA:0003104enteric muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR002867IBR_dom
IPR019169Transmembrane_26
Vocabulary: cellular component
TermDefinition
GO:0000151ubiquitin ligase complex
GO:0005737cytoplasm
GO:0005813centrosome
GO:0005815microtubule organizing center
GO:0005856cytoskeleton
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0000209protein polyubiquitination
GO:0016567protein ubiquitination
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Vocabulary: molecular function
TermDefinition
GO:0004842ubiquitin-protein transferase activity
GO:0008270zinc ion binding
GO:0016740transferase activity
GO:0031624ubiquitin conjugating enzyme binding
GO:0046872metal ion binding
GO:0061630ubiquitin protein ligase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 17..53