Bifunctional glutamate/proline--tRNA ligase

Query:   66 ILNWKNFSKNILKNND-LKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            I +W  FS   L + D    ++N LN  ++ RTYLV +SLS AD  ++ TL  N  +Q  LK    P++V R++  L+     +++ T  + S  K  V  EK              ++ GKFV L     G V VRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF+ ++KY E+LI+   AY D+T A QMK ERE++  SK R   +E+NL+ W  MK G++ G   C+R K+DM+SNNGCMRDPT+YRCK + H RTG KY VYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ I++ L +RKP I +YSRL L NTVLSKRKLT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY AL    + ++ V + +  E +++ V +HPKN  +G K VW++P VF+E  DA  F+E   VTFINWGN+ ITKIHKN++  I S+DAKLNL ++D+KKT KVTW+     +      IPV  + Y++LITK VLGKD+DFK ++N++SK EE ++GD  LK+LKKGDIIQLQR+G+FICD+ Y+     + K+ P VLI IP+G++KE  T G K+K++ +
Sbjct:   78 IDHWLEFSATKLSSCDSFTSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWFGFLEAQQAFQSVGTKWDVSTTKARVAPEKK-------------QDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVAL--LKKEVIPVNVPEAQEEMKE-VAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNLNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWL----AETTHALPIPVICVTYEHLITKPVLGKDEDFKQYVNKNSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVE 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRD--GKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKP-KYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+Y+DI GCYIL P    IWE I++  +  I+  GV+ C FP F+S+S+L KEK H+ADF+PEVAWVT +G   L EPIAIRPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGH+A++   +A EEV QILDLYA VYE+LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQG TSHHLGQNFSKMF+I FE     G+++F +QNSWG+TTRTIG++ MVHGD+ GLVLPPRVA  QVVI+PCG+T   +E++ EA++ KC     RL +  IRV ADL  + SPG+KFN+WELKGVPIR+E+GP+++ +   V   R  G K ++ +   E  ++  LE I   +F +A  +L  H  VA TMED    L+   ++  PFCG+  CED IK  +A +  +E GAPSMGAKSLCIPF+  C L  G KC+   C   P KY+T+FGRSY
Sbjct: 1009 KKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCV---CGKNPAKYYTLFGRSY 1512          

Query:   66 ILNWKNFSKNILKNND-LKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFN-------KKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            I +W  FS   L + D    ++N LN  ++ RTYLV +SLS AD  ++ TL  N  +Q  LK    P++V R++  L+     +++ T  + S  K  V  EK              ++ GKFV L     G V VRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF+ ++KY E+LI+   AY D+T A QMK ERE++  SK R   +E+NL+ W  MK G++ G   C+R K+DM+SNNGCMRDPT+YRCK + H RTG KY VYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ I++ L +RKP I +YSRL L NTVLSKRKLT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFN       KKVIDP+APRY AL    + ++ V + +  E +++ V +HPKN  +G K VW++P VF+E  DA  F+E   VTFINWGN+ ITKIHKN++  I S+DAKLNL ++D+KKT KVTW+     +      IPV  + Y++LITK VLGKD+DFK ++N++SK EE ++GD  LK+LKKGDIIQLQR+G+FICD+ Y+     + K+ P VLI IP+G++KE  T G K+K++ +
Sbjct:   78 IDHWLEFSATKLSSCDSFTSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWFGFLEAQQAFQSVGTKWDVSTTKARVAPEKK-------------QDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKLRALCKKVIDPVAPRYVAL--LKKEVIPVNVPEAQEEMKE-VAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNLNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWL----AETTHALPIPVICVTYEHLITKPVLGKDEDFKQYVNKNSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVE 729          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTF--INWGN----------ILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKR-EECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKE-----NCSITGKQYP 1979
            + G V  RFPPE +G LHIGHAKA   N  Y     G   +RFDDTNP KE  +F   I + V  LG +    +Y+SD+FD L  +  ELI+   AY  +    ++K        S  R++ +EE+L  +  M+ G     +  +R+K+ M   +G M DP  YR K   H RTG K+ +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L   V+SKRK+  +V  G V  WDDPR+ T+  + R G   E +  F    G   A   ME   L A  + V++  APR  A+  S R  V++      + ++  V   P +E  G   V F P VF+ER    DF E     F  + WG           I +  + K     + S++     +D   K    + W+  PL    R+ +         + +   ++       F + LN  S    +  + D  +   K  D  Q +R GYF  D +  +     N ++T K+ P
Sbjct:  115 TGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGH--NTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVME--DGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLR--VIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIER---TDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYER-------LFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDP 627          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTF--INWGN----------ILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKR-EECLIGDVELKNLKKGDIIQLQRKGYFICDEE 1940
            + G V  RFPPE +G LHIGHAKA   N  Y     G   +RFDDTNP KE  +F   I + V  LG +    +Y+SD+FD L  +  ELI+   AY  +    ++K        S  R++ +EE+L  +  M+ G     +  +R+K+ M   +G M DP  YR K   H RTG K+ +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L   V+SKRK+  +V  G V  WDDPR+ T+  + R G   E +  F    G   A   ME   L A  + V++  APR  A+  S R  V++      + ++  V   P +E  G   V F P VF+ER    DF E     F  + WG           I +  + K     + S++     +D   K    + W+  PL    R+ +         + +   ++       F + LN  S    +  + D  +   K  D  Q +R GYF  D +
Sbjct:  204 TGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGH--NTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVME--DGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLR--VIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIER---TDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYER-------LFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDPD 698          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTF--INWGN----------ILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKR-EECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKE-----NCSITGKQYP 1979
            + G V  RFPPE +G LHIGHAKA   N  Y     G   +RFDDTNP KE  +F   I + V  LG +    +Y+SD+FD L  +  ELI+   AY  +    ++K        S  R++ +EE+L  +  M+ G     +  +R+K+ M   +G M DP  YR K   H RTG K+ +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L   V+SKRK+  +V  G V  WDDPR+ T+  + R G   E +  F    G   A   ME   L A  + V++  APR  A+  S R  V++      + ++  V   P +E  G   V F P VF+ER    DF E     F  + WG           I +  + K     + S++     +D   K    + W+  PL    R+ +         + +   ++       F + LN  S    +  + D  +   K  D  Q +R GYF  D +  +     N ++T K+ P
Sbjct:  260 TGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGH--NTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVME--DGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLR--VIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIER---TDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYER-------LFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDP 772          

Query:  429 FVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERA 2024
            FV L    KG VVVRFPPEASGYLHIGHAKAAL+NQ+Y+  + G+LIMRFDDTNPAKE   FE +I ED+  L +  D +++SSDHF++L+  CE+L+K   A+ D+TD   M+ ERE++  S+ R+ T E+NL+ W  MK G+ +GL  C+R+K+DM SNNG MRDPTIYRCKPE HVRTG KYKVYPTYDFTCPIVDS+EGVTH LRT+EY+DR++Q++ I D L LR+P I +Y+RL + NTV+SKRKLT+ V+EG+V+GWDDPR+PTVRG++R G+T+EGLK+F++AQG  R+ V+MEWDK+WAFNKKVIDP+APRYTAL  S   LV + + D +     +V  HPKN  IG K V     + +E+ DA    E   VTF+NWGNI I KI K    VIT I A L L + D+KKT KVTW  LG         IPV    YD++I+K ++GKD+D+K F+N DS     ++G+  +KN+KKGDIIQ+QRKG++I D+ Y     ++G + PL+LI IP+G++ + A
Sbjct:  183 FVELPGAEKGKVVVRFPPEASGYLHIGHAKAALLNQYYQQAFEGQLIMRFDDTNPAKENAHFEHVIKEDLSMLNIVPDRWTHSSDHFEMLLTMCEKLLKEGKAFVDDTDTETMRNEREQRQDSRNRSNTPEKNLQLWEEMKKGSPKGLTCCVRMKIDMKSNNGAMRDPTIYRCKPEEHVRTGLKYKVYPTYDFTCPIVDSVEGVTHALRTTEYHDRDDQYYFICDALGLRRPHIWEYARLNMTNTVMSKRKLTWFVDEGHVEGWDDPRLPTVRGVMRRGLTVEGLKQFIVAQGGSRSVVMMEWDKIWAFNKKVIDPVAPRYTALD-STSPLVSIELTDSISDDTSNVSLHPKNAEIGSKDVHKGKKLLLEQVDAAALKEGEIVTFVNWGNIKIGKIEKKGA-VITKISATLQLDNTDYKKTTKVTW--LGDVKAEAGKTIPVVTADYDHIISKAIIGKDEDWKQFINFDSVHYTKMVGEPAIKNVKKGDIIQIQRKGFYIVDQPYNPKSELSGVETPLLLIAIPDGHTGKEA 710          

Query:  429 FVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERA 2024
            FV L    KG VVVRFPPEASGYLHIGHAKAAL+NQ+Y+  + G+LIMRFDDTNPAKE   FE +I ED+  L +  D +++SSDHF++L+  CE+L+K   A+ D+TD   M+ ERE++  S+ R+ T E+NL+ W  MK G+ +GL  C+R+K+DM SNNG MRDPTIYRCKPE HVRTG KYKVYPTYDFTCPIVDS+EGVTH LRT+EY+DR++Q++ I D L LR+P I +Y+RL + NTV+SKRKLT+ V+EG+V+GWDDPR+PTVRG++R G+T+EGLK+F++AQG  R+ V+MEWDK+WAFNKKVIDP+APRYTAL  S   LV + + D +     +V  HPKN  IG K V     + +E+ DA    E   VTF+NWGNI I KI K    VIT I A L L + D+KKT KVTW  LG         IPV    YD++I+K ++GKD+D+K F+N DS     ++G+  +KN+KKGDIIQ+QRKG++I D+ Y     ++G + PL+LI IP+G++ + A
Sbjct:  183 FVELPGAEKGKVVVRFPPEASGYLHIGHAKAALLNQYYQQAFEGQLIMRFDDTNPAKENAHFEHVIKEDLSMLNIVPDRWTHSSDHFEMLLTMCEKLLKEGKAFVDDTDTETMRNEREQRQDSRNRSNTPEKNLQLWEEMKKGSPKGLTCCVRMKIDMKSNNGAMRDPTIYRCKPEEHVRTGLKYKVYPTYDFTCPIVDSVEGVTHALRTTEYHDRDDQYYFICDALGLRRPHIWEYARLNMTNTVMSKRKLTWFVDEGHVEGWDDPRLPTVRGVMRRGLTVEGLKQFIVAQGGSRSVVMMEWDKIWAFNKKVIDPVAPRYTALD-STSPLVSIELTDSISDDTSNVSLHPKNAEIGSKDVHKGKKLLLEQVDAAALKEGEIVTFVNWGNIKIGKIEKKGA-VITKISATLQLDNTDYKKTTKVTW--LGDVKAEAGKTIPVVTADYDHIISKAIIGKDEDWKQFINFDSVHYTKMVGEPAIKNVKKGDIIQIQRKGFYIVDQPYNPKSELSGVETPLLLIAIPDGHTGKEA 710          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCN-LGDKCINSECSMKPKYFTMFGRSY 3758
            KK T LG+   K+DN+SEWY +VITK E+I+YYD+ GCY+L P +  +WE IQ   ++ I+  GVK C FP F+S ++L +EK HIADF+PEVAWVT AG+  + EPIAIRPTSET MYP Y K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++N  DA +EV QILDLYA VY DLLAIPVVKGRK+EKEKFAG DFTTT E Y+  +GR IQGATSHHLGQNFSKMFDI +E  +++G++ F +QNSWG++TRTIG +VM+HGDD+GLVLPPRVA  QV++VP G       +  +++ +   K+   L    ++   DL  + + G+KFN+WELKGVPIR E+GP +LA N V    R+NG K+ +  E L + V+  L+ IH AM+ K   + D+H      +E+    L+ K +I +PFCG   CE+ IK  S  E    EGA  MGAK+LCIP +QP   L  KC+   C+   K F +FGRSY
Sbjct:   84 KKQTLLGVGTKKDDNYSEWYSEVITKAEMIEYYDVSGCYVLRPWSFAVWESIQEWFDSGIKKLGVKNCYFPMFVSNAALEREKTHIADFAPEVAWVTRAGNSEMAEPIAIRPTSETVMYPSYKKWVQSHRDLPIKLNQWCNVVRWEFKHPTPFLRTREFLWQEGHTAFANPADAEKEVFQILDLYAGVYTDLLAIPVVKGRKSEKEKFAGGDFTTTVEAYVACNGRGIQGATSHHLGQNFSKMFDISYEDPAKEGERAFAWQNSWGLSTRTIGAMVMIHGDDKGLVLPPRVAAVQVIVVPVGFKT----ENKQSLFDAVDKVTKDLVADGVKAEHDLRENYNAGWKFNHWELKGVPIRFEVGPNDLAKNQVTAVIRHNGEKKQLSLEGLSKTVKSLLDEIHTAMYNKVLAQRDSHLKSTTCIEEFKKLLDEKCIILSPFCGRPDCEEEIKKASTRED--GEGA-QMGAKTLCIPLDQPKQELPSKCLFPSCTYNAKAFALFGRSY 581          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCN-LGDKCINSECSMKPKYFTMFGRSY 3758
            KK T LG+   K+DN+SEWY +VITK E+I+YYD+ GCY+L P +  +WE IQ   ++ I+  GVK C FP F+S ++L +EK HIADF+PEVAWVT AG+  + EPIAIRPTSET MYP Y K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++N  DA +EV QILDLYA VY DLLAIPVVKGRK+EKEKFAG DFTTT E Y+  +GR IQGATSHHLGQNFSKMFDI +E  +++G++ F +QNSWG++TRTIG +VM+HGDD+GLVLPPRVA  QV++VP G       +  +++ +   K+   L    ++   DL  + + G+KFN+WELKGVPIR E+GP +LA N V    R+NG K+ +  E L + V+  L+ IH AM+ K   + D+H      +E+    L+ K +I +PFCG   CE+ IK  S  E    EGA  MGAK+LCIP +QP   L  KC+   C+   K F +FGRSY
Sbjct:   84 KKQTLLGVGTKKDDNYSEWYSEVITKAEMIEYYDVSGCYVLRPWSFAVWESIQEWFDSGIKKLGVKNCYFPMFVSNAALEREKTHIADFAPEVAWVTRAGNSEMAEPIAIRPTSETVMYPSYKKWVQSHRDLPIKLNQWCNVVRWEFKHPTPFLRTREFLWQEGHTAFANPADAEKEVFQILDLYAGVYTDLLAIPVVKGRKSEKEKFAGGDFTTTVEAYVACNGRGIQGATSHHLGQNFSKMFDISYEDPAKEGERAFAWQNSWGLSTRTIGAMVMIHGDDKGLVLPPRVAAVQVIVVPVGFKT----ENKQSLFDAVDKVTKDLVADGVKAEHDLRENYNAGWKFNHWELKGVPIRFEVGPNDLAKNQVTAVIRHNGEKKQLSLEGLSKTVKSLLDEIHTAMYNKVLAQRDSHLKSTTCIEEFKKLLDEKCIILSPFCGRPDCEEEIKKASTRED--GEGA-QMGAKTLCIPLDQPKQELPSKCLFPSCTYNAKAFALFGRSY 581          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANN 3353
            KK T LG+   K+DN+SEWY +VITK E+I+YYD+ GCY+L P +  +WE IQ   ++ I+  GVK C FP F+S ++L +EK HIADF+PEVAWVT AG+  + EPIAIRPTSET MYP Y K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++N  DA +EV QILDLYA VY DLLAIPVVKGRK+EKEKFAG DFTTT E Y+  +GR IQGATSHHLGQNFSKMFDI +E  +++G++ F +QNSWG++TRTIG +VM+HGDD+GLVLPPRVA  QV++VP G       +  +++ +   K+   L    ++   DL  + + G+KFN+WELKGVPIR E+GP +LA N
Sbjct:   84 KKQTLLGVGTKKDDNYSEWYSEVITKAEMIEYYDVSGCYVLRPWSFAVWESIQEWFDSGIKKLGVKNCYFPMFVSNAALEREKTHIADFAPEVAWVTRAGNSEMAEPIAIRPTSETVMYPSYKKWVQSHRDLPIKLNQWCNVVRWEFKHPTPFLRTREFLWQEGHTAFANPADAEKEVFQILDLYAGVYTDLLAIPVVKGRKSEKEKFAGGDFTTTVEAYVACNGRGIQGATSHHLGQNFSKMFDISYEDPAKEGERAFAWQNSWGLSTRTIGAMVMIHGDDKGLVLPPRVAAVQVIVVPVGFKT----ENKQSLFDAVDKVTKDLVADGVKAEHDLRENYNAGWKFNHWELKGVPIRFEVGPNDLAKN 448          

Query:   66 ILNWKNFSKNILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMK 2039
            I +W +FS  +   +D+  +L++L+ SIA  TYLV + L+ AD  ++  +++   F   L A  +P +V R+Y+ +     I+ +L       K   VK      KE+      + ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQ+Y   + G LIMRFDDTNPAKET EFE +IL D++ L +  D F+++S++FDL++ YC  LIK   AY D+T   QMK ERE++  S  R+ +VE+NL  W  M  G+E+G +YC+R K+DM+S NGCMRDPTIYRCK E H RTG KYKVYPTYDF CPIVD+IE VTHTLRT+EY+DR++QF+  +D L LRKP I  YSRL + NTVLSKRKLT+ V+ G VDGWDDPR PTVRGI+R GMT+EGLKEF++AQG  ++ V M WDK+WAFNKKVIDPIAPRYTAL    R +V V    ++E ++ SV  HPK+E++G+K+V   P ++++  DA    E  N TFINWGNILI K++K++   ITS+DA LNL ++DFKKT K+TW+ +  +      + P   +++DN+I+K VLGKD+DFK F+   ++ E  ++GD ELK  KKGDIIQLQR+G+F  D  Y      T    P+VL +IP+G++K+  T G+K
Sbjct:   80 IDHWLSFS--LTCEDDISWALSFLDKSIAPVTYLVANKLTIADFALFNEMHSRYEF---LAAKGIPQHVQRWYDLITAQPLIQKVLQSLPEDAK---VKRSPQSSKEQTPAKTGERKQEGKFVDLPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQYYALAFQGTLIMRFDDTNPAKETVEFENVILGDLEQLQIKPDVFTHTSNYFDLMLDYCVRLIKESKAYVDDTPPEQMKLEREQRVESANRSNSVEKNLSLWEEMVKGSEKGQKYCVRAKIDMSSPNGCMRDPTIYRCKNEPHPRTGTKYKVYPTYDFACPIVDAIENVTHTLRTTEYHDRDDQFYWFIDALKLRKPYIWSYSRLNMTNTVLSKRKLTWFVDSGLVDGWDDPRFPTVRGIIRRGMTVEGLKEFIIAQGSSKSVVFMNWDKIWAFNKKVIDPIAPRYTALEKEKRVIVNVAGA-KVERIQVSV--HPKDESLGKKTVLLGPRIYIDYVDAEALKEGENATFINWGNILIRKVNKDASGNITSVDAALNLENKDFKKTLKLTWLAVEDD---PSAYPPTFCVYFDNIISKAVLGKDEDFKQFIGHKTRDEVPMLGDPELKKCKKGDIIQLQRRGFFKVDVAYAPPSGYTNVPSPIVLFSIPDGHTKDVPTSGLK 723          

Query: 2208 KTVENQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRDGKQ-EFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNLG--DKCINSECSMKPKYFTMFGRSY 3758
            K V+ +  A     +KK TRLGLE +KEDN  +WY QVITKGE+I+YYD+ GCYIL   +  IW+ I+   +  I   GVK C FP F+SK+ L KEK HIADF+PEVAWVT +GD +L EPIA+RPTSET MYP Y+K ++S+RDLP++ NQW +VVRWEFK P PFLR+REFLWQEGHTA+++K +A +EV  ILDLYA VY  LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I +E  + +Q ++V+QNSWG+TTRTIG+++MVH D++GLVLPP VA  Q ++VPCG+T+   + E   +++ C+ L  RL    +R   D   + SPG+KFN+WELKGVP+R+E+GPK+L    +V   R    K +I    +E+ +   LE IHE+M  KA+ ++ +H        D    L +K ++ APFCG+ +CED+IK  SA     E GAP+MGAKSLCIPF+QP  +   DKCIN  C+ KPK++T+FGRSY
Sbjct: 1195 KPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDPETQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEEAEPGAPAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY 1714          

Query: 2208 KTVENQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRDGKQ-EFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNLG--DKCINSECSMKPKYFTMFGRSY 3758
            K V+ +  A     +KK TRLGLE +KEDN  +WY QVITKGE+I+YYD+ GCYIL   +  IW+ I+   +  I   GVK C FP F+SK+ L KEK HIADF+PEVAWVT +GD +L EPIA+RPTSET MYP Y+K ++S+RDLP++ NQW +VVRWEFK P PFLR+REFLWQEGHTA+++K +A +EV  ILDLYA VY  LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I +E  + +Q ++V+QNSWG+TTRTIG+++MVH D++GLVLPP VA  Q ++VPCG+T+   + E   +++ C+ L  RL    +R   D   + SPG+KFN+WELKGVP+R+E+GPK+L    +V   R    K +I    +E+ +   LE IHE+M  KA+ ++ +H        D    L +K ++ APFCG+ +CED+IK  SA     E GAP+MGAKSLCIPF+QP  +   DKCIN  C+ KPK++T+FGRSY
Sbjct:  477 KPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDPETQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEEAEPGAPAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY 996          

Query:  456 GNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNG-TEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDD 1547
            G V  RFPPE +G LHIGHAKA  IN  Y   + G   +R+DDTNP KE E+F   I E V+ LG      +YSSD+F  L ++   LI    AY  +  A ++K    +   S  R + +EE+L+ +  MK G  +EG      ++M +    G M DP  YR K   H RTG  + +YPTYD+T  + DS+E +TH+L T E+  R   ++ + + L +  P   +Y RL +   ++SKRK+  ++ E  V  WDDPR+ T+  + R G   E +  F    G   A + ++   L A  + V++  APR   +    +  V ++       V+  V   P+N   G   +     +++E+ D
Sbjct:  265 GKVHTRFPPEPNGILHIGHAKAININFGYAAAHDGVCYLRYDDTNPEKEEEKFFLAIKEMVEWLGYKPFKITYSSDNFQQLYEWAVVLINKGLAYVCHQKAEELKGFNPKP--SPWRERPIEESLRLFEDMKRGKIDEG---AATLRMKVTLEEGKM-DPVAYRIKFISHHRTGSDWCIYPTYDYTHCLCDSLEDITHSLCTKEFQSRRSSYYWLCNALGIYCPVQWEYGRLNMNYALVSKRKIAKLITEQIVHDWDDPRLFTLTALRRRGFPAEAINNFCAQMGVTGAQIAVDPAMLEAAVRDVLNVTAPRRLVVLEPLK--VTIKNFPHAAPVQLEVPDFPQNPQQGTHKITLDKVIYIEQGD 621          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFS---------YSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTIS--------KCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKM-----------------DMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLA-LQNTVLSKRK 1181
            +   V VRF P  +GYLH+G  + AL N  Y  H  GK ++R +DT+  +      + ++ED+   G+  D              S   ++  K  EEL+ +  AY       ++   R+E   +        KCR+ T  E     +L+  GT     YCIR K+                 +++ N G   DP +             K   +PTY F   + D + G+TH LR  E+     +   +      + P+      L     T LSKR+
Sbjct:   17 AHSQVRVRFAPSPTGYLHLGGLRTALYNFLYARHLGGKFLLRIEDTDQTRLVPGASERLVEDLLWAGIEIDEGPGFGGQLGPYVQSQRTEIYSKAIEELLHNGTAYRCFCTERRLDLLRKEALRTRQVPRYDNKCRHLTTSE---VDSLLAKGTP----YCIRFKLTDHEEPLDDLIYGKVHHNVSDNEG---DPVV------------MKSDQFPTYHFANVVDDHLMGITHVLRGVEWQISTTKHLLLYKAFGWQPPKFGHLPLLVNADGTKLSKRQ 273          

Query:   42 LMDQASILILNWKNFS-KNILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQT---LDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTKP 2060
            +M+Q  +   +W  FS + +   +DL  +L  L+ ++A RT+LV  S++ AD  I+  L  N   Q   K  S P ++ R+++ L +      + +    K S+ K  +V+ +K              ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF  +++  E+L++   AY D+T    MK+ERE++  S+ RN +VE+N++ W  MK GTE G   C+R K+DMNSNNGC+RDP ++RCK   H RTG  YKVYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ +++ L LRKP I +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT++GLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APR+TAL  S    V+   V + +     V +HPKN ++G K VW+ P VF+E  DA  F E   VTFINWGNI+ITKIH++S   I S+D  LNL + D+KKT K+TW  L  + R    F+P   + Y +LITK VLGKDDDFK+++N++SK EE +IGD  LK+LKKGDIIQLQR+G++ICD+ Y+     + ++ P VL+ IP+G++KE  T G K KS+++P
Sbjct:   71 MMEQTEVD--HWLEFSARRLCGQSDLSSALADLDKALALRTFLVGRSVTLADLCIWAALKGNGESQ--AKPSSHP-HLCRWFSFLSSQVPFSSVGSKWASKVSASKAASVEKDKK-------------QDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTILRMGEKLLQEGKAYIDDTPPDIMKQEREQRAESRNRNNSVEKNMQMWEEMKKGTEFGQTCCMRAKIDMNSNNGCLRDPALFRCKNAAHPRTGTTYKVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVIEALGLRKPYIWEYARLNLNNTVLSKRKLTWFVDKGYVDGWDDPRFPTVRGVLRRGMTVDGLKQFIAAQGGSRSVVNMEWDKIWAFNKKVIDPVAPRFTALLSSQ---VIPVCVSEAKETMKEVPKHPKNADVGLKQVWYGPKVFIEGADAETFTEGEIVTFINWGNIIITKIHRDSSGAILSLDGHLNLENTDYKKTTKITW--LAESSRAS--FVPTVCVNYQHLITKPVLGKDDDFKDYINKNSKIEEKMIGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCRESPCVLLYIPDGHTKEMPTAGSKDKSKSQP 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+YYD+ GCY+L P +  IW+ I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA VYE+L+AIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFS+MF+I FE   + G+++  +QNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QV+I+PCG+T    E E + ++++C K   RL+ A+IRV ADL  + SPG+KFN+WELKGVPIR E+GPK+L     V   R  G K ++ +   E+ +   LE I   +F +A ++L+ H  VA TME     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF+   NL  G  C++ +     +Y+T+FGRSY
Sbjct: 1180 KKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWDAIKEFFDREIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSRMFEIVFEDPKKPGEKQLAYQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACLQVIIIPCGITATLPEAEKDLLLDQCSKYLSRLQKADIRVKADLRDNYSPGWKFNHWELKGVPIRFEVGPKDLKQGQFVAVRRDTGEKITVKEADAEKKIPNLLEEIQNNLFKRASDDLNKHMVVADTMEQFQKDLDQGRIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFKPLKNLQAGQMCVSGKEPA--QYYTLFGRSY 1683          

Query:   42 LMDQASILILNWKNFS-KNILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQT---LDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTKP 2060
            +M+Q  +   +W  FS + +   +DL  +L  L+ ++A RT+LV  S++ AD  I+  L  N   Q   K  S P ++ R+++ L +      + +    K S+ K  +V+ +K              ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF  +++  E+L++   AY D+T    MK+ERE++  S+ RN +VE+N++ W  MK GTE G   C+R K+DMNSNNGC+RDP ++RCK   H RTG  YKVYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ +++ L LRKP I +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT++GLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APR+TAL  S    V+   V + +     V +HPKN ++G K VW+ P VF+E  DA  F E   VTFINWGNI+ITKIH++S   I S+D  LNL + D+KKT K+TW+   S       F+P   + Y +LITK VLGKDDDFK+++N++SK EE +IGD  LK+LKKGDIIQLQR+G++ICD+ Y+     + ++ P VL+ IP+G++KE  T G K KS+++P
Sbjct:   71 MMEQTEVD--HWLEFSARRLCGQSDLSSALADLDKALALRTFLVGRSVTLADLCIWAALKGNGESQ--AKPSSHP-HLCRWFSFLSSQVPFSSVGSKWASKVSASKAASVEKDKK-------------QDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTILRMGEKLLQEGKAYIDDTPPDIMKQEREQRAESRNRNNSVEKNMQMWEEMKKGTEFGQTCCMRAKIDMNSNNGCLRDPALFRCKNAAHPRTGTTYKVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVIEALGLRKPYIWEYARLNLNNTVLSKRKLTWFVDKGYVDGWDDPRFPTVRGVLRRGMTVDGLKQFIAAQGGSRSVVNMEWDKIWAFNKKVIDPVAPRFTALLSSQ---VIPVCVSEAKETMKEVPKHPKNADVGLKQVWYGPKVFIEGADAETFTEGEIVTFINWGNIIITKIHRDSSGAILSLDGHLNLENTDYKKTTKITWLAESSRAS----FVPTVCVNYQHLITKPVLGKDDDFKDYINKNSKIEEKMIGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCRESPCVLLYIPDGHTKEMPTAGSKDKSKSQP 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+YYD+ GCY+L P +  IW+ I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA VYE+L+AIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFS+MF+I FE   + G+++  +QNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QV+I+PCG+T    E E + ++++C K   RL+ A+IRV ADL  + SPG+KFN+WELKGVPIR E+GPK+L     V   R  G K ++ +   E+ +   LE I   +F +A ++L+ H  VA TME     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF+   NL  G  C++ +     +Y+T+FGRSY
Sbjct: 1095 KKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWDAIKEFFDREIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSRMFEIVFEDPKKPGEKQLAYQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACLQVIIIPCGITATLPEAEKDLLLDQCSKYLSRLQKADIRVKADLRDNYSPGWKFNHWELKGVPIRFEVGPKDLKQGQFVAVRRDTGEKITVKEADAEKKIPNLLEEIQNNLFKRASDDLNKHMVVADTMEQFQKDLDQGRIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFKPLKNLQAGQMCVSGKEPA--QYYTLFGRSY 1598          

Query:  456 GNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTA-LSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDD 1547
            G V  RFPPE +G LHIGHAKA   N  +     G   +R+DDTNP KE E++   I + V+ LG      +++SD+F  L     +LI+  +AY  +    ++K        S  R + VEE+L  +  M+ G     +  +R+KM M   +G M DP  YR K   H RTG  + +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L  TV+SKRK+  +V  G V  WDDPR+ T+  + R G   + +  F    G   A   ME   L A  ++V++  APR  A L     +++ +    Q E+    V   P NE  G   V F+ T+F+E+ D
Sbjct:  261 GQVRTRFPPEPNGILHIGHAKAINFNFGFAKANNGICFLRYDDTNPEKEEEKYFTAIKDMVEWLGYEPYAVTHASDNFQRLYNLAVDLIRRGHAYVCHQRGEELKGHNVPS--SPWRERPVEESLVLFEHMRKGMFAEGEATLRMKMVME--DGKM-DPVAYRIKYTPHHRTGDTWCIYPTYDYTHCLCDSIENITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLTYTVVSKRKIIKLVETGVVRDWDDPRLFTLTALRRRGFPPQAINNFCARVGVTVAQTTMEPHLLEACVREVLNDTAPRAMAILEPLKVTIINLPTNAQKEL---RVPDFPANEARGSHVVPFSKTIFIEQSD 617          

Query:  456 GNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTC 1013
            G V  RFPPE +G LHIGHAKA   N  +     G   +R+DDTNP KE E++   I + V+ LG      +++SD+F  L     +LI+  +AY  +    ++K        S  R + VEE+L  +  M+ G     +  +R+KM M   +G M DP  YR K   H RTG  +++   YD T 
Sbjct:  261 GQVRTRFPPEPNGILHIGHAKAINFNFGFAKANNGICFLRYDDTNPEKEEEKYFTAIKDMVEWLGYEPYAVTHASDNFQRLYNLAVDLIRRGHAYVCHQRGEELKGHNVPS--SPWRERPVEESLVLFEHMRKGMFAEGEATLRMKMVM--EDGKM-DPVAYRIKYTPHHRTGDTWRIQERYDQTS 441          

Query:  888 IKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYN 1070
            +K +M   +G M DP  YR K   H RTG  + +YPTYD+T  + DSIE +TH+L T E+ 
Sbjct:  164 VKNEMVMEDGKM-DPVAYRIKYTPHHRTGDTWCIYPTYDYTHCLCDSIENITHSLCTKEFQ 223          

Query:   66 ILNWKNFSKN-ILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLE-IVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            + +W  FS+  +++  +    L  LN  ++ RTYLV ++L+ AD  ++  L  +  +Q L++    P+NV R+Y+ L+      +   +K  S KK                     ++ GKFV L     G V+VRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHFD ++KY E+LI+   AY D+T A QMK ERE++  SK R+ TV +N++ W  MK GTE G   C+R K+DMNSNNGCMRDPT++RCK + H RTG KY +YPTYDF CPIVDS+EGVTH LRT+EY+DR+EQF+ I+D L +RKP I +YSRL L NTVLSKR+LT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY+AL  S    V V I D  E +VE  V +HPKN  +GQK VW+ P V +E  DA   +E   VTFINWGN++ITKIH++    I S+DAKLNL ++D+KKT K+TW+     +  +  FIP S + YD+LITK VLGK++DFK ++NR SK+EE ++GD  LK+LKKGD+IQLQR+G++ICDE Y+     + K+ P VLI IP+G++KE  T G K+KS+T+
Sbjct:  128 VSHWMEFSQTKLMQKGEFSTGLQELNHCLSLRTYLVGNALTLADICVFSALEASSEWQALVQKGQTPVNVRRWYSFLEPQLGFWSRTNNKVPSEKK---------------------QDVGKFVELPGAEMGKVIVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVSMLQIKPDQFTYTSDHFDTIMKYAEKLIQEGKAYVDDTPAEQMKSEREQRIESKHRSNTVAKNMEMWEDMKKGTEYGQTCCLRAKIDMNSNNGCMRDPTLFRCKNQPHPRTGSKYNIYPTYDFACPIVDSVEGVTHALRTTEYHDRDEQFYWIIDALGIRKPYIWEYSRLNLNNTVLSKRRLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYSALLKSQ--AVAVNIPDAKEGMVE--VAKHPKNAEVGQKPVWYGPKVLIEGADAETLSEGETVTFINWGNLIITKIHRDQSGKIQSLDAKLNLENKDYKKTTKITWL----AETPKAPFIPTSCVNYDHLITKPVLGKEEDFKQYVNRSSKQEEVMLGDPCLKDLKKGDLIQLQRRGFYICDEPYEPISPHSCKEAPCVLIYIPDGHTKEMPTSGSKEKSKTE 764          

Query: 2220 NQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            + S A +    KK TRLGLE  KE+N  +WY QVITK E+I+YYD+ GCY+L P    IWE I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++   +A EEV QILDLYA VYEDLLAIPVVKGRKTEKEKFAG D+TTT E +I +S RAIQGATSHHLGQNFSKMF+I FE     G +++ +QNSWG++TRTIG + MVH D+ G+VLPPRVA  QV+I+PCG+T   +E++ +A+++KC +   RL   ++R  AD+  + SPG+KFN+WELKGVPIR+E+GP+++ N   V   R NG K++I +++ E  ++E LE IH  ++ +A ++L ++  VA TMED    L +  ++  PFCG+  CED IK V+A +  +E GAPSMGAKSLCIPF+    L    KC+  + +   K++T+FGRSY
Sbjct: 1194 DNSAAGESQGPKKQTRLGLEAKKEENLPDWYSQVITKSEMIEYYDVSGCYVLRPWAFAIWEAIKEFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATYEEAAEEVLQILDLYARVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASSRAIQGATSHHLGQNFSKMFEIVFEDPKTPGLKQYAYQNSWGLSTRTIGAMTMVHADNIGMVLPPRVACVQVIIIPCGITNTLSEEDKDALLKKCDQYLKRLLNVDVRARADVRDNYSPGWKFNHWELKGVPIRLEVGPRDMKNKQFVAVRRDNGEKQTISEDQAETRLKEILEEIHTNLYNRALSDLTSNMVVANTMEDFQKNLEKGRIVQIPFCGEIECEDWIKKVTARDQDLEPGAPSMGAKSLCIPFKPLSELQPSAKCVCEKNAA--KFYTLFGRSY 1708          

Query:   66 ILNWKNFSKN-ILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLE-IVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            + +W  FS+  +++  +    L  LN  ++ RTYLV ++L+ AD  ++  L  +  +Q L++    P+NV R+Y+ L+      +   +K  S KK                     ++ GKFV L     G V+VRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHFD ++KY E+LI+   AY D+T A QMK ERE++  SK R+ TV +N++ W  MK GTE G   C+R K+DMNSNNGCMRDPT++RCK + H RTG KY +YPTYDF CPIVDS+EGVTH LRT+EY+DR+EQF+ I+D L +RKP I +YSRL L NTVLSKR+LT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY+AL  S    V V I D  E +VE  V +HPKN  +GQK VW+ P V +E  DA   +E   VTFINWGN++ITKIH++    I S+DAKLNL ++D+KKT K+TW+     +  +  FIP S + YD+LITK VLGK++DFK ++NR SK+EE ++GD  LK+LKKGD+IQLQR+G++ICDE Y+     + K+ P VLI IP+G++KE  T G K+KS+T+
Sbjct:  128 VSHWMEFSQTKLMQKGEFSTGLQELNHCLSLRTYLVGNALTLADICVFSALEASSEWQALVQKGQTPVNVRRWYSFLEPQLGFWSRTNNKVPSEKK---------------------QDVGKFVELPGAEMGKVIVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVSMLQIKPDQFTYTSDHFDTIMKYAEKLIQEGKAYVDDTPAEQMKSEREQRIESKHRSNTVAKNMEMWEDMKKGTEYGQTCCLRAKIDMNSNNGCMRDPTLFRCKNQPHPRTGSKYNIYPTYDFACPIVDSVEGVTHALRTTEYHDRDEQFYWIIDALGIRKPYIWEYSRLNLNNTVLSKRRLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYSALLKSQ--AVAVNIPDAKEGMVE--VAKHPKNAEVGQKPVWYGPKVLIEGADAETLSEGETVTFINWGNLIITKIHRDQSGKIQSLDAKLNLENKDYKKTTKITWL----AETPKAPFIPTSCVNYDHLITKPVLGKEEDFKQYVNRSSKQEEVMLGDPCLKDLKKGDLIQLQRRGFYICDEPYEPISPHSCKEAPCVLIYIPDGHTKEMPTSGSKEKSKTE 764          

Query: 2220 NQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            + S A +    KK TRLGLE  KE+N  +WY QVITK E+I+YYD+ GCY+L P    IWE I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++   +A EEV QILDLYA VYEDLLAIPVVKGRKTEKEKFAG D+TTT E +I +S RAIQGATSHHLGQNFSKMF+I FE     G +++ +QNSWG++TRTIG + MVH D+ G+VLPPRVA  QV+I+PCG+T   +E++ +A+++KC +   RL   ++R  AD+  + SPG+KFN+WELKGVPIR+E+GP+++ N   V   R NG K++I +++ E  ++E LE IH  ++ +A ++L ++  VA TMED    L +  ++  PFCG+  CED IK V+A +  +E GAPSMGAKSLCIPF+    L    KC+  + +   K++T+FGRSY
Sbjct: 1119 DNSAAGESQGPKKQTRLGLEAKKEENLPDWYSQVITKSEMIEYYDVSGCYVLRPWAFAIWEAIKEFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATYEEAAEEVLQILDLYARVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASSRAIQGATSHHLGQNFSKMFEIVFEDPKTPGLKQYAYQNSWGLSTRTIGAMTMVHADNIGMVLPPRVACVQVIIIPCGITNTLSEEDKDALLKKCDQYLKRLLNVDVRARADVRDNYSPGWKFNHWELKGVPIRLEVGPRDMKNKQFVAVRRDNGEKQTISEDQAETRLKEILEEIHTNLYNRALSDLTSNMVVANTMEDFQKNLEKGRIVQIPFCGEIECEDWIKKVTARDQDLEPGAPSMGAKSLCIPFKPLSELQPSAKCVCEKNAA--KFYTLFGRSY 1633          

Query:   66 ILNWKNFSKN-ILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLE-IVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            + +W  FS+  +++  +    L  LN  ++ RTYLV ++L+ AD  ++  L  +  +Q L++    P+NV R+Y+ L+      +   +K  S KK                     ++ GKFV L     G V+VRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHFD ++KY E+LI+   AY D+T A QMK ERE++  SK R+ TV +N++ W  MK GTE G   C+R K+DMNSNNGCMRDPT++RCK + H RTG KY +YPTYDF CPIVDS+EGVTH LRT+EY+DR+EQF+ I+D L +RKP I +YSRL L NTVLSKR+LT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY+AL  S    V V I D  E +VE  V +HPKN  +GQK VW+ P V +E  DA   +E   VTFINWGN++ITKIH++    I S+DAKLNL ++D+KKT K+TW+     +  +  FIP S + YD+LITK VLGK++DFK ++NR SK+EE ++GD  LK+LKKGD+IQLQR+G++ICDE Y+     + K+ P VLI IP+G++KE  T G K+KS+T+
Sbjct:  128 VSHWMEFSQTKLMQKGEFSTGLQELNHCLSLRTYLVGNALTLADICVFSALEASSEWQALVQKGQTPVNVRRWYSFLEPQLGFWSRTNNKVPSEKK---------------------QDVGKFVELPGAEMGKVIVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVSMLQIKPDQFTYTSDHFDTIMKYAEKLIQEGKAYVDDTPAEQMKSEREQRIESKHRSNTVAKNMEMWEDMKKGTEYGQTCCLRAKIDMNSNNGCMRDPTLFRCKNQPHPRTGSKYNIYPTYDFACPIVDSVEGVTHALRTTEYHDRDEQFYWIIDALGIRKPYIWEYSRLNLNNTVLSKRRLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYSALLKSQ--AVAVNIPDAKEGMVE--VAKHPKNAEVGQKPVWYGPKVLIEGADAETLSEGETVTFINWGNLIITKIHRDQSGKIQSLDAKLNLENKDYKKTTKITWL----AETPKAPFIPTSCVNYDHLITKPVLGKEEDFKQYVNRSSKQEEVMLGDPCLKDLKKGDLIQLQRRGFYICDEPYEPISPHSCKEAPCVLIYIPDGHTKEMPTSGSKEKSKTE 764          

Query: 2220 NQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            + S A +    KK TRLGLE  KE+N  +WY QVITK E+I+YYD+ GCY+L P    IWE I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++   +A EEV QILDLYA VYEDLLAIPVVKGRKTEKEKFAG D+TTT E +I +S RAIQGATSHHLGQNFSKMF+I FE     G +++ +QNSWG++TRTIG + MVH D+ G+VLPPRVA  QV+I+PCG+T   +E++ +A+++KC +   RL   ++R  AD+  + SPG+KFN+WELKGVPIR+E+GP+++ N   V   R NG K++I +++ E  ++E LE IH  ++ +A ++L ++  VA TMED    L +  ++  PFCG+  CED IK V+A +  +E GAPSMGAKSLCIPF+    L    KC+  + +   K++T+FGRSY
Sbjct: 1152 DNSAAGESQGPKKQTRLGLEAKKEENLPDWYSQVITKSEMIEYYDVSGCYVLRPWAFAIWEAIKEFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATYEEAAEEVLQILDLYARVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASSRAIQGATSHHLGQNFSKMFEIVFEDPKTPGLKQYAYQNSWGLSTRTIGAMTMVHADNIGMVLPPRVACVQVIIIPCGITNTLSEEDKDALLKKCDQYLKRLLNVDVRARADVRDNYSPGWKFNHWELKGVPIRLEVGPRDMKNKQFVAVRRDNGEKQTISEDQAETRLKEILEEIHTNLYNRALSDLTSNMVVANTMEDFQKNLEKGRIVQIPFCGEIECEDWIKKVTARDQDLEPGAPSMGAKSLCIPFKPLSELQPSAKCVCEKNAA--KFYTLFGRSY 1666          

Query:   66 ILNWKNFSKN-ILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFN-------KKVIDPIAPRYTALSGSDRSLVLVRIVDQLE-IVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            + +W  FS+  +++  +    L  LN  ++ RTYLV ++L+ AD  ++  L  +  +Q L++    P+NV R+Y+ L+      +   +K  S KK                     ++ GKFV L     G V+VRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHFD ++KY E+LI+   AY D+T A QMK ERE++  SK R+ TV +N++ W  MK GTE G   C+R K+DMNSNNGCMRDPT++RCK + H RTG KY +YPTYDF CPIVDS+EGVTH LRT+EY+DR+EQF+ I+D L +RKP I +YSRL L NTVLSKR+LT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFN       KKVIDP+APRY+AL  S    V V I D  E +VE  V +HPKN  +GQK VW+ P V +E  DA   +E   VTFINWGN++ITKIH++    I S+DAKLNL ++D+KKT K+TW+     +  +  FIP S + YD+LITK VLGK++DFK ++NR SK+EE ++GD  LK+LKKGD+IQLQR+G++ICDE Y+     + K+ P VLI IP+G++KE  T G K+KS+T+
Sbjct:  128 VSHWMEFSQTKLMQKGEFSTGLQELNHCLSLRTYLVGNALTLADICVFSALEASSEWQALVQKGQTPVNVRRWYSFLEPQLGFWSRTNNKVPSEKK---------------------QDVGKFVELPGAEMGKVIVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVSMLQIKPDQFTYTSDHFDTIMKYAEKLIQEGKAYVDDTPAEQMKSEREQRIESKHRSNTVAKNMEMWEDMKKGTEYGQTCCLRAKIDMNSNNGCMRDPTLFRCKNQPHPRTGSKYNIYPTYDFACPIVDSVEGVTHALRTTEYHDRDEQFYWIIDALGIRKPYIWEYSRLNLNNTVLSKRRLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKLRAICKKVIDPVAPRYSALLKS--QAVAVNIPDAKEGMVE--VAKHPKNAEVGQKPVWYGPKVLIEGADAETLSEGETVTFINWGNLIITKIHRDQSGKIQSLDAKLNLENKDYKKTTKITWL----AETPKAPFIPTSCVNYDHLITKPVLGKEEDFKQYVNRSSKQEEVMLGDPCLKDLKKGDLIQLQRRGFYICDEPYEPISPHSCKEAPCVLIYIPDGHTKEMPTSGSKEKSKTE 771          

Query: 2220 NQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            + S A +    KK TRLGLE  KE+N  +WY QVITK E+I+YYD+ GCY+L P    IWE I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++   +A EEV QILDLYA VYEDLLAIPVVKGRKTEKEKFAG D+TTT E +I +S RAIQGATSHHLGQNFSKMF+I FE     G +++ +QNSWG++TRTIG + MVH D+ G+VLPPRVA  QV+I+PCG+T   +E++ +A+++KC +   RL   ++R  AD+  + SPG+KFN+WELKGVPIR+E+GP+++ N   V   R NG K++I +++ E  ++E LE IH  ++ +A ++L ++  VA TMED    L +  ++  PFCG+  CED IK V+A +  +E GAPSMGAKSLCIPF+    L    KC+  + +   K++T+FGRSY
Sbjct: 1201 DNSAAGESQGPKKQTRLGLEAKKEENLPDWYSQVITKSEMIEYYDVSGCYVLRPWAFAIWEAIKEFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATYEEAAEEVLQILDLYARVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASSRAIQGATSHHLGQNFSKMFEIVFEDPKTPGLKQYAYQNSWGLSTRTIGAMTMVHADNIGMVLPPRVACVQVIIIPCGITNTLSEEDKDALLKKCDQYLKRLLNVDVRARADVRDNYSPGWKFNHWELKGVPIRLEVGPRDMKNKQFVAVRRDNGEKQTISEDQAETRLKEILEEIHTNLYNRALSDLTSNMVVANTMEDFQKNLEKGRIVQIPFCGEIECEDWIKKVTARDQDLEPGAPSMGAKSLCIPFKPLSELQPSAKCVCEKNAA--KFYTLFGRSY 1715          

Query:   66 ILNWKNFSKN-ILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFN-------KKVIDPIAPRYTALSGSDRSLVLVRIVDQLE-IVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            + +W  FS+  +++  +    L  LN  ++ RTYLV ++L+ AD  ++  L  +  +Q L++    P+NV R+Y+ L+      +   +K  S KK                     ++ GKFV L     G V+VRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHFD ++KY E+LI+   AY D+T A QMK ERE++  SK R+ TV +N++ W  MK GTE G   C+R K+DMNSNNGCMRDPT++RCK + H RTG KY +YPTYDF CPIVDS+EGVTH LRT+EY+DR+EQF+ I+D L +RKP I +YSRL L NTVLSKR+LT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFN       KKVIDP+APRY+AL  S    V V I D  E +VE  V +HPKN  +GQK VW+ P V +E  DA   +E   VTFINWGN++ITKIH++    I S+DAKLNL ++D+KKT K+TW+     +  +  FIP S + YD+LITK VLGK++DFK ++NR SK+EE ++GD  LK+LKKGD+IQLQR+G++ICDE Y+     + K+ P VLI IP+G++KE  T G K+KS+T+
Sbjct:  128 VSHWMEFSQTKLMQKGEFSTGLQELNHCLSLRTYLVGNALTLADICVFSALEASSEWQALVQKGQTPVNVRRWYSFLEPQLGFWSRTNNKVPSEKK---------------------QDVGKFVELPGAEMGKVIVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVSMLQIKPDQFTYTSDHFDTIMKYAEKLIQEGKAYVDDTPAEQMKSEREQRIESKHRSNTVAKNMEMWEDMKKGTEYGQTCCLRAKIDMNSNNGCMRDPTLFRCKNQPHPRTGSKYNIYPTYDFACPIVDSVEGVTHALRTTEYHDRDEQFYWIIDALGIRKPYIWEYSRLNLNNTVLSKRRLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKLRAICKKVIDPVAPRYSALLKS--QAVAVNIPDAKEGMVE--VAKHPKNAEVGQKPVWYGPKVLIEGADAETLSEGETVTFINWGNLIITKIHRDQSGKIQSLDAKLNLENKDYKKTTKITWL----AETPKAPFIPTSCVNYDHLITKPVLGKEEDFKQYVNRSSKQEEVMLGDPCLKDLKKGDLIQLQRRGFYICDEPYEPISPHSCKEAPCVLIYIPDGHTKEMPTSGSKEKSKTE 771          

Query: 2220 NQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            + S A +    KK TRLGLE  KE+N  +WY QVITK E+I+YYD+ GCY+L P    IWE I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++   +A EEV QILDLYA VYEDLLAIPVVKGRKTEKEKFAG D+TTT E +I +S RAIQGATSHHLGQNFSKMF+I FE     G +++ +QNSWG++TRTIG + MVH D+ G+VLPPRVA  QV+I+PCG+T   +E++ +A+++KC +   RL   ++R  AD+  + SPG+KFN+WELKGVPIR+E+GP+++ N   V   R NG K++I +++ E  ++E LE IH  ++ +A ++L ++  VA TMED    L +  ++  PFCG+  CED IK V+A +  +E GAPSMGAKSLCIPF+    L    KC+  + +   K++T+FGRSY
Sbjct: 1201 DNSAAGESQGPKKQTRLGLEAKKEENLPDWYSQVITKSEMIEYYDVSGCYVLRPWAFAIWEAIKEFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATYEEAAEEVLQILDLYARVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASSRAIQGATSHHLGQNFSKMFEIVFEDPKTPGLKQYAYQNSWGLSTRTIGAMTMVHADNIGMVLPPRVACVQVIIIPCGITNTLSEEDKDALLKKCDQYLKRLLNVDVRARADVRDNYSPGWKFNHWELKGVPIRLEVGPRDMKNKQFVAVRRDNGEKQTISEDQAETRLKEILEEIHTNLYNRALSDLTSNMVVANTMEDFQKNLEKGRIVQIPFCGEIECEDWIKKVTARDQDLEPGAPSMGAKSLCIPFKPLSELQPSAKCVCEKNAA--KFYTLFGRSY 1715          

Query:   66 ILNWKNFSKNILKNND-LKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            I +W  FS   L + D L  ++N LN  ++ RTYLV +SL+ AD  ++ TL  +  +Q  LK +   ++V R++  L+     +++ T  + SG + TV  +K              ++ GKFV L     G V VRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF+ ++KY E+LI+   AY D+T A QMK ERE++T SK R  +VE+NL+ W  MK G++ G   C+R K+DM+SNNGCMRDPT+YRCK + H RTG KY VYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ I++ L +RKP I +YSRL L NTVLSKRKLT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY AL    + +V V ++D  E +++ V RHPKN ++G K VW++P VF+E  DA  F+E   VTFINWGNI ITKIHKN++  ITS+DAKLNL ++D+KKT K+TW+     +      IP   + Y++LITK VLGKD+DFK ++N+DSK EE ++GD  LK+LKKGDIIQLQR+G+FICD+ Y+     + ++ P +LI IP+G++KE  T G K+K++ +
Sbjct:   78 IDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWDVSGNRATVAPDKK-------------QDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRTESKHRKNSVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVAL--LKKEVVPVNVLDAQEEMKE-VARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWL----AESTHALSIPAVCVTYEHLITKPVLGKDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCREAPCILIYIPDGHTKEMPTSGSKEKTKVE 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKP-KYFTMFGRSY 3758
            KK TRLGLE  KE+N +EWY QVITK E+I+YYD+ GCYIL P +  IWE I++  +  I+  GV+ C FP F+S+++L KEK+HI DF+PEVAWVT +G   L EPIAIRPTSET MYP Y+K ++SHRDLP++ NQWC+VVRWEFKHP PFLR+REFLWQEGH+A++   +A +EV QIL+LYA VYE+LLAIPVV+GRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKM +I FE     G+++F +Q SWG+TTRTIG++VMVHGD+ GLVLPPRVA  QVV++PCG+T   +E++ EA+M KC +   RL  A IRV  DL  + SPG+KFN+WELKGVP+R+E+GP+++ +   V   R  G K +I ++  E  +E+ LE I   +F +A  +L  H  V+ T+ED    L+   +   PFCG+  CED IK ++A +  VE GAPSMGAKSLCIPF   C L  G  C+   C   P K++T+FGRSY
Sbjct: 1009 KKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLEKVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQDVEPGAPSMGAKSLCIPFNPLCELQPGAMCV---CGKNPAKFYTLFGRSY 1512          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVD--------FAENTNVTFINWGNIL-ITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDS-KREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKE-----NCSITGKQYP 1979
            + G V  RFPPE +G LHIGHAKA   N  Y     G   +RFDDTNP KE  +F   I + V  LG +    +Y+SD+FD L  +  ELI    AY  +    ++K        S  R++  EE+L  +  M+ G     +  +R+K+ M   +G M DP  YR K   H RTG K+ +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L   V+SKRK+  +V  G V  WDDPR+ T+  + R G   E +  F    G   A   ME   L A  + V++  APR  A++  +   V++      + ++  V   P +E  G   V F  TVF+ER D  +         A    V   + G ++ +  I + S   +  ++     +D   K    + W+  PL    R+ +         + +   ++ +     F + LN  S +  E  + D  +   K  D  Q +R GYF  D +  +     N ++T K+ P
Sbjct:  236 TGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVTWLGYTPYKVTYASDYFDQLYAWAVELIHGGLAYVCHQRVEELKGH--NPLPSPWRDRPKEESLLLFEAMRKGKFAEGEATLRMKLVME--DGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALKVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDAAPR--AMAVLEPLQVVITNFPAPKPLDIRVPNFPADETKGFHQVPFASTVFIERSDFKEESEPGYKRLASGQPVGLRHTGYVIELQNIVRGSSGCVERLEVTCRRADAGEKPKAFIHWVSQPLVCEIRLYE-------CLFQHKNPEDPVEVPGGFLSDLNPASLQVVEGALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGQIVFNRTVTLKEDP 748          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVD--------FAENTNVTFINWGNIL-ITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDS-KREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKE-----NCSITGKQYP 1979
            + G V  RFPPE +G LHIGHAKA   N  Y     G   +RFDDTNP KE  +F   I + V  LG +    +Y+SD+FD L  +  ELI    AY  +    ++K        S  R++  EE+L  +  M+ G     +  +R+K+ M   +G M DP  YR K   H RTG K+ +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L   V+SKRK+  +V  G V  WDDPR+ T+  + R G   E +  F    G   A   ME   L A  + V++  APR  A++  +   V++      + ++  V   P +E  G   V F  TVF+ER D  +         A    V   + G ++ +  I + S   +  ++     +D   K    + W+  PL    R+ +         + +   ++ +     F + LN  S +  E  + D  +   K  D  Q +R GYF  D +  +     N ++T K+ P
Sbjct:  260 TGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVTWLGYTPYKVTYASDYFDQLYAWAVELIHGGLAYVCHQRVEELKGH--NPLPSPWRDRPKEESLLLFEAMRKGKFAEGEATLRMKLVME--DGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALKVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDAAPR--AMAVLEPLQVVITNFPAPKPLDIRVPNFPADETKGFHQVPFASTVFIERSDFKEESEPGYKRLASGQPVGLRHTGYVIELQNIVRGSSGCVERLEVTCRRADAGEKPKAFIHWVSQPLVCEIRLYE-------CLFQHKNPEDPVEVPGGFLSDLNPASLQVVEGALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGQIVFNRTVTLKEDP 772          

Query:  894 MDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEF 1292
            M +   +G M DP  YR K   H RTG K+ +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L   V+SKRK+  +V  G V  WDDPR+ T+  + R G   E +  F
Sbjct:    2 MKLVMEDGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALKVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNF 133          

Query:  456 GNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSL 647
            G V  RFPPE +G LHIGHAKA   N  Y     G   +RFDDTNP KE  +F   I + V  L
Sbjct:   52 GQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVIHL 115          

Query:   66 ILNWKNFSKNILKNND-LKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            I +W  FS   L + D L  ++N LN  ++ RTYLV +SL+ AD  ++ TL  +  +Q  LK +   ++V R++  L+     +++ T  + SG + TV  +K              ++ GKFV L     G V VRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF+ ++KY E+LI+   AY D+T A QMK ERE++T SK R  +VE+NL+ W  MK G++ G   C+R K+DM+SNNGCMRDPT+YRCK + H RTG KY VYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ I++ L +RKP I +YSRL L NTVLSKRKLT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY AL    + +V V ++D  E +++ V RHPKN ++G K VW++P VF+E  DA  F+E   VTFINWGNI ITKIHKN++  ITS+DAKLNL ++D+KKT K+TW+     +      IP   + Y++LITK VLGKD+DFK ++N+DSK EE ++GD  LK+LKKGDIIQLQR+G+FICD+ Y+     + ++ P +LI IP+G++KE  T G K+K++ +
Sbjct:   78 IDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWDVSGNRATVAPDKK-------------QDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRTESKHRKNSVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVAL--LKKEVVPVNVLDAQEEMKE-VARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWL----AESTHALSIPAVCVTYEHLITKPVLGKDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCREAPCILIYIPDGHTKEMPTSGSKEKTKVE 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKP-KYFTMFGRSY 3758
            KK TRLGLE  KE+N +EWY QVITK E+I+YYD+ GCYIL P +  IWE I++  +  I+  GV+ C FP F+S+++L KEK+HI DF+PEVAWVT +G   L EPIAIRPTSET MYP Y+K ++SHRDLP++ NQWC+VVRWEFKHP PFLR+REFLWQEGH+A++   +A +EV QIL+LYA VYE+LLAIPVV+GRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKM +I FE     G+++F +Q SWG+TTRTIG++VMVHGD+ GLVLPPRVA  QVV++PCG+T   +E++ EA+M KC +   RL  A IRV  DL  + SPG+KFN+WELKGVP+R+E+GP+++ +   V   R  G K +I ++  E  +E+ LE I   +F +A  +L  H  V+ T+ED    L+   +   PFCG+  CED IK ++A +  VE GAPSMGAKSLCIPF   C L  G  C+   C   P K++T+FGRSY
Sbjct: 1009 KKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLEKVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQDVEPGAPSMGAKSLCIPFNPLCELQPGAMCV---CGKNPAKFYTLFGRSY 1512          

Query:   66 ILNWKNFSKNILKN-NDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTKP 2060
            I +W  FS   L +   L  +L  LN  ++ RTYLV +SL+ AD  ++ TL  N  +Q  L+ +   ++V R++  L+     +++ T  + S  K  V  +K              ++ GKFV L     G V VRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF+ ++KY E+LI+   AY D+T A QMK ERE++  SK R  +VE+NL+ W  MK G+  G   C+R K+DM+SNNGCMRDPT+YRCK + H RTG KY VYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ I++ L +RKP I +YSRL L NTVLSKRKLT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY AL    + +V V + +  E +++ V RHPKN ++G K VW++P VF+E  DA  F+E   VTFINWGNI ITKIHKN++  ITS+DAKLNL ++D+KKT K+TW+     +      IP   + Y++LITK VLGKD+DFK ++N+DSK EE ++GD  LK+LKKGDIIQLQR+G+FICD+ Y+     + K+ P +LI IP+G++KE  T G K+K++ +P
Sbjct:   78 IDHWLEFSATKLSSCAALTSALTELNHCLSLRTYLVGNSLTLADLCVWATLKGNAAWQEQLEQNKTLVHVKRWFGFLEAQQAFRSVGTKWDVSENKARVVPDKK-------------QDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRAESKHRQNSVEKNLQMWEEMKKGSPFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVAL--LKKEVVPVNVPEAQEEMKE-VARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWL----AETTHALPIPAICVTYEHLITKPVLGKDEDFKQYVNKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTKAEP 723          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKP-KYFTMFGRSY 3758
            KK TRLGLE  KE+N +EWY QVITK E+I+YYD+ GCYIL P +  IWE I++  +T I+  GV+ C FP F+S+++L KEK HI DF+PEVAWVT +G   L EPIAIRPTSET MYP Y+K ++SHRDLP++ NQWC+VVRWEFKHP PFLR+REFLWQEGH+A++   +A +EV QIL+LYA VYE+LLAIPVV+GRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKM +I FE     G+++F FQ SWG+TTRTIG+++MVHGD+ GLVLPPRVA  QVV++PCG+T   +E++ EA+M KC +   RL    IRV  DL  + SPG+KFN+WELKGVP+R+E+GP+++ +   V   R  G K +I ++  E  ++E LE I   +F +A  +L  H  V+ T+ED    L+   +   PFCG+  CED IK  +A +  VE GAPSMGAKSLCIPF   C L  G  C+   C   P K++T+FGRSY
Sbjct: 1008 KKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDTEIKKLGVENCYFPIFVSQAALEKEKSHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVMQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAFQCSWGLTTRTIGVMIMVHGDNMGLVLPPRVACVQVVVIPCGITNALSEEDREALMAKCNEYRKRLLGVNIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAESKLQEILEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDSGKIAQIPFCGEIDCEDWIKKTTARDQDVEPGAPSMGAKSLCIPFTPLCELQPGAMCV---CGKNPAKFYTLFGRSY 1511          

Query:   66 ILNWKNFSKNILKNND-LKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            I +W  FS   L + D    ++N LN  ++ RTYLV +SLS AD  ++ TL  N  +Q  LK    P++V R++  L+     +++ T  + S  K  V  EK              ++ GKFV L     G V VRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF+ ++KY E+LI+   AY D+T A QMK ERE++  SK R   +E+NL+ W  MK G++ G   C+R K+DM+SNNGCMRDPT+YRCK + H RTG KY VYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ I++ L +RKP I +YSRL L NTVLSKRKLT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY AL    + ++ V + +  E +++ V +HPKN  +G K VW++P VF+E  DA  F+E   VTFINWGN+ ITKIHKN++  I S+DAKLNL ++D+KKT KVTW+     +      IPV  + Y++LITK VLGKD+DFK ++N++SK EE ++GD  LK+LKKGDIIQLQR+G+FICD+ Y+     + K+ P VLI IP+G++KE  T G K+K++ +
Sbjct:   78 IDHWLEFSATKLSSCDSFTSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWFGFLEAQQAFQSVGTKWDVSTTKARVAPEKK-------------QDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVAL--LKKEVIPVNVPEAQEEMKE-VAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNLNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWL----AETTHALPIPVICVTYEHLITKPVLGKDEDFKQYVNKNSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVE 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRD--GKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKP-KYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+Y+DI GCYIL P    IWE I++  +  I+  GV+ C FP F+S+S+L KEK H+ADF+PEVAWVT +G   L EPIAIRPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGH+A++   +A EEV QILDLYA VYE+LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQG TSHHLGQNFSKMF+I FE     G+++F +QNSWG+TTRTIG++ MVHGD+ GLVLPPRVA  QVVI+PCG+T   +E++ EA++ KC     RL +  IRV ADL  + SPG+KFN+WELKGVPIR+E+GP+++ +   V   R  G K ++ +   E  ++  LE I   +F +A  +L  H  VA TMED    L+   ++  PFCG+  CED IK  +A +  +E GAPSMGAKSLCIPF+  C L  G KC+   C   P KY+T+FGRSY
Sbjct: 1009 KKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAKCV---CGKNPAKYYTLFGRSY 1512          

Query:   66 ILNWKNFSKNILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMK 2039
            I +W +FS  +   +D+  +L++L+ SIA  TYLV + L+ AD  ++  +++   F   L A  +P +V R+Y+ +     I+ +L       K   VK      KE+      + ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQ+Y   + G LIMRFDDTNPAKET EFE +IL D++ L +  D F+++S++FDL++ YC  LIK   AY D+T   QMK ERE++  S  R+ +VE+NL  W  M  G+E+G +YC+R K+DM+S NGCMRDPTIYRCK E H RTG KYKVYPTYDF CPIVD+IE VTHTLRT+EY+DR++QF+  +D L LRKP I  YSRL + NTVLSKRKLT+ V+ G VDGWDDPR PTVRGI+R GMT+EGLKEF++AQG  ++ V M WDK+WAFNKKVIDPIAPRYTAL    R +V V    ++E ++ SV  HPK+E++G+K+V   P ++++  DA    E  N TFINWGNILI K++K++   ITS+DA LNL ++DFKKT K+TW+ +  +      + P   +++DN+I+K VLGKD+DFK F+   ++ E  ++GD ELK  KKGDIIQLQR+G+F  D  Y      T    P+VL +IP+G++K+  T G+K
Sbjct:   80 IDHWLSFS--LTCEDDISWALSFLDKSIAPVTYLVANKLTIADFALFNEMHSRYEF---LAAKGIPQHVQRWYDLITAQPLIQKVLQSLPEDAK---VKRSPQSSKEQTPAKTGERKQEGKFVDLPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQYYALAFQGTLIMRFDDTNPAKETVEFENVILGDLEQLQIKPDVFTHTSNYFDLMLDYCVRLIKESKAYVDDTPPEQMKLEREQRVESANRSNSVEKNLSLWEEMVKGSEKGQKYCVRAKIDMSSPNGCMRDPTIYRCKNEPHPRTGTKYKVYPTYDFACPIVDAIENVTHTLRTTEYHDRDDQFYWFIDALKLRKPYIWSYSRLNMTNTVLSKRKLTWFVDSGLVDGWDDPRFPTVRGIIRRGMTVEGLKEFIIAQGSSKSVVFMNWDKIWAFNKKVIDPIAPRYTALEKEKRVIVNVAGA-KVERIQVSV--HPKDESLGKKTVLLGPRIYIDYVDAEALKEGENATFINWGNILIRKVNKDASGNITSVDAALNLENKDFKKTLKLTWLAVEDD---PSAYPPTFCVYFDNIISKAVLGKDEDFKQFIGHKTRDEVPMLGDPELKKCKKGDIIQLQRRGFFKVDVAYAPPSGYTNVPSPIVLFSIPDGHTKDVPTSGLK 723          

Query: 2208 KTVENQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRDGKQ-EFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNLG--DKCINSECSMKPKYFTMFGRSY 3758
            K V+ +  A     +KK TRLGLE +KEDN  +WY QVITKGE+I+YYD+ GCYIL   +  IW+ I+   +  I   GVK C FP F+SK+ L KEK HIADF+PEVAWVT +GD +L EPIA+RPTSET MYP Y+K ++S+RDLP++ NQW +VVRWEFK P PFLR+REFLWQEGHTA+++K +A +EV  ILDLYA VY  LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I +E  + +Q ++V+QNSWG+TTRTIG+++MVH D++GLVLPP VA  Q ++VPCG+T+   + E   +++ C+ L  RL    +R   D   + SPG+KFN+WELKGVP+R+E+GPK+L    +V   R    K +I    +E+ +   LE IHE+M  KA+ ++ +H        D    L +K ++ APFCG+ +CED+IK  SA     E GAP+MGAKSLCIPF+QP  +   DKCIN  C+ KPK++T+FGRSY
Sbjct: 1195 KPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDPETQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEEAEPGAPAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY 1714          

Query: 2250 LKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFES---RDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEG-----APSMGAKSLCIPFEQPC-NLGDKCINSECSMKPKYFTMFGRSY 3758
            L+    +G+ V K  +F  WY Q++TKGE++DYYD+ GCYIL P +  IWE IQ   +  I+A GV+   FP F+S   L KEKDH+  F+PEVAWVT AG   LEEPIAIRPTSET MYP+Y+K ++S+RDLPLK NQW SVVRWEFKHP PFLR+REFLWQEGHTA+    DA EEV QILD YA VYE+LLA+PVVKGRKTEKEKFAG DFTTT E YI  +GR IQGATSHHLGQNFSKMF++  E+    D  + F +QNSWG++TR IG++VM+H D++GLV+PPRV++ Q V++P G+T K +E++ + + E  + +  RLK   IR + D + + +PG+KF+ +ELKG+PIRIE+GPK++  N VV+  R +  K  +  + LE  + E LE +   +F KAK   D HR +       +  LN+K +I AP+CG   CE+ IK  SA +   EE      APSMGAKSLCIPF+QP  N G KCI  +C      + MFGRSY
Sbjct:  179 LEDAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCYILRPPSYAIWENIQKWFDDKIKAIGVQNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPYYAKWVQSYRDLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHTAHLTAKDAEEEVLQILDFYAGVYEELLAVPVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPLGSDHPKIFAYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQRKHIHETARSVESRLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQVVVVRRNDSKKYVVSFDELEARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVMECEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPFDQPVLNEGQKCI--KCERIAVNYCMFGRSY 688          

Query:  414 EEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEE-LIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSL------RKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTA--LSGSDRSLVLVRIVDQLEIVE--------DSVGRHPKNENIGQKS-VWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKN-SENVITSIDAKLNLSDRDFKKTQKVTWMP---LGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREEC-LIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLQNENKTVENQSEASKKTELKKVTRLGLEVSK-EDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAK--GVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRDG-KQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLK---------------------TAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIM----------DERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKI-VSAGEAVVEEGAPSMGAKSLCIPFEQP-----CNLGDKCINSECSMKPKYFTMFGRSY 3758
            ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+  + G+LI+RFDDTNPAKE E+FEK+ILED+  L +  D F+Y+SDHFD ++  CE  ++K   AY D+T+  +++ ERE+K  S  RN ++E+NL+ W  M  GTE GL+ C+R K+DM S NGC+RDPTIYRCKPE H RTG KYKVYPTYDF CPIVDS EGVTH LRT+EY DR+ Q++   D L L       +P +  YSRL + NTVLSKRKLT+ V +G+VDGWDDPRMPTVRG+ R GM +E LK+F++AQG  R    M+WDK+W+ N+ ++D IAPR+TA  LS S++   ++       +VE        D+V +HPKN  +G K+ VW  P + ++  DA         TFINWGN+LI +I +N + N I  I A  +L + DFK T KVTW+P      ++ +    +P+  +++D+LI+K VL KDDDFK +LN ++ R E  +IGD ELK+LKKGD+IQLQR+GYFICD  Y+     +GK+  LVL NIP+G+ K   T+ +   +                                            +K   + EN  V   S  + K    KVT+LGLEV K  +N  EWY QV+ KGE+I+YYD+ GCY+L P    IWE IQ   +  I+ K   ++ C FP F+S+ +L +EK+HIADF+PEVAWVT +G+ +L EPIAIRPTSET MYP ++K I+S+RDLPLK NQW SVVRWEFKHP PFLR+REFLWQEGH AY+ + +A  +V   L  Y  VY+++LA+PV+KG+KTEKEKFAG  FTTT E Y+ SSGRAIQGATSH+LG NF+KMFD+ FE  D  K+ FV Q S+GMTTRTIG++VMVHGDDRGLVLPPR+A  QV+IVPCG+ +K + +  + +   C  + +RLK                     +  IR   DL  + SPG+KFN+WELKGVP+R+E+GPK+L+ N ++   R NG K +I           ++++   + E L  I + M+ KA+ E+  +  +     +    L  K L+  PFCG   CED IK   +  +   + GA +MGAKSLC+PFEQP         D+CI+ +C      FT+FGRSY
Sbjct:    9 KQQGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQLAFNGRLILRFDDTNPAKEKEDFEKVILEDIDMLKIKPDTFTYTSDHFDQMLDICENGMLKEGLAYVDDTNGDEIRLEREKKIESINRNNSIEKNLELWKQMVLGTEIGLKCCVRAKIDMQSANGCLRDPTIYRCKPEHHPRTGDKYKVYPTYDFACPIVDSFEGVTHCLRTTEYTDRDAQYYWFCDALKLGTRSNETRPYVWSYSRLNMTNTVLSKRKLTWFVEQGHVDGWDDPRMPTVRGVFRRGMQVEALKQFIVAQGSSRTVTAMQWDKIWSLNRSIVDSIAPRHTALLLSNSNKENAVLSYPPVEVVVENVEKPYKIDNVPKHPKNVQLGLKNCVWAAPKILIDYSDAELLEAGRRATFINWGNLLINRIERNQNNNNIERIYAVSDLENTDFKSTVKVTWLPKIDYSESEEVLPILVPIVCVYFDHLISKAVLAKDDDFKQYLNTENSRWELQMIGDSELKDLKKGDVIQLQRRGYFICDSTYQPYSIHSGKEMSLVLFNIPDGHRKSITTIPLPISTSN----------------------------------------IKDKKLKKKENIAVATDSSINAK----KVTKLGLEVQKVSENLGEWYSQVLVKGEMIEYYDVSGCYVLRPWAYRIWELIQEWFDARIKRKPLNIQNCYFPMFVSQGALEREKEHIADFAPEVAWVTKSGETDLAEPIAIRPTSETGMYPAFAKWIQSYRDLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHNAYATREEAERDVLITLGYYEYVYKNMLAVPVIKGKKTEKEKFAGGIFTTTCEAYVASSGRAIQGATSHYLGTNFAKMFDVHFEHPDTHKKSFVHQISFGMTTRTIGVMVMVHGDDRGLVLPPRIASIQVIIVPCGVGVKTSNEVKDNLTRTCLDVCNRLKGDSLIESDDENDNSVIQHRNSSLIIRADTDLRDNYSPGWKFNHWELKGVPLRLEIGPKDLSRNQIIAVRRDNGDKLTIPLEGRPKDDGGNDKMVIRITELLNQIQQDMYNKAEQEMKENVVICRKWSECAAHLAAKHLLLIPFCGRPICEDNIKQDTTLDDGTADLGASTMGAKSLCVPFEQPKGADILKSNDQCIHPKCGHPAGSFTLFGRSY 1143          

Query:  411 FEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLQNENKTVENQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE-SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAG--EAVVEEG----APSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
             E+GG+FV L    KG+VVVRFPPEASGYLHIGHAKAAL+NQ Y+D Y GKLI+RFDDTNP KE   FE+IILEDVK L L+ D +S +SD+FD L+ Y E +IK   AY DNT   +M++ R +K  S  R+ +V+ NL  W  +K G E    +C+R K+D  S NGC+RDPTIYR  P+ H  +G KY VYPTYDF CPIVDSIEGVTH LRTSEY+DR+ Q+   LD L+LRKP I +YSRL+ Q TVLSKRKLT +V+   VDGWDDPRMPT+RG++R G+T+  LKEF+LAQGF ++ V M+ DKLWAFNK+ ++PI+PR   L G D  LV   I   +      +   PK+E  G ++++F   + +E  D+    +   VT INWGN  +     + E     I   L   + D+  T K++W  L +   +E+  IP+  + Y NL+ K+VL  +DDF+ ++N++SK     +G+    NLK+G+I+Q+ RKG++  D ++       GK   L L+ +P G    +           KP+ +      K+ K  K       +++  K  +    + K+ K+   +  + +  + +  KKT+L      GL VSKE +FS+WY +VITK ELIDYY I GCY++ P    IWE +Q   +  ++  G++ C FP F+ +S+L KEKDHI DF+PEVAWVT AG  +L EPIAIRPTSET +YP  +K I+SHRDLPLK NQWC+VVRWEFKHP PF+R+REFLWQEGHT Y+++ DAV+EV+QILDLY  +Y +LLAIPVVKG K+E EKFAGA+FTTT E YI + GR +QGATSHHLGQNFSKMFDI FE S   +++FVFQNS+G++TR +G LVMVHGDD+GLVLPPRVA  QVVI+PCG++   TE+    + E  Q LA  LK  ++RV+ D   + +PG+K+N+WE+KGVP+R+E+GPK+L+ +TV +  R  G K S+  E   + + E LE I  +M+ KA  +L  +  +    +  IN LN K +I +PFCGDK CE+ ++  S    E V E+G      SMGAK+LCIP  QP  L  G+KCI   C    K + +FGRS+
Sbjct:  169 LEDGGRFVELPGAVKGSVVVRFPPEASGYLHIGHAKAALLNQFYRDRYEGKLILRFDDTNPVKEKCHFEEIILEDVKLLELTPDMYSKTSDYFDSLLNYAEVMIKRGLAYCDNTPTDEMRQLRTQKAPSMYRDTSVDMNLARWEQLKAGKET--DWCLRAKIDYASENGCLRDPTIYRYCPDPHPTSGQKYHVYPTYDFACPIVDSIEGVTHALRTSEYHDRDPQYLWFLDQLTLRKPVIFEYSRLSFQYTVLSKRKLTKVVDSHIVDGWDDPRMPTIRGLIRRGLTLGALKEFILAQGFSKSVVNMQTDKLWAFNKRFLEPISPRLIGLIGDD--LVKAEITSDIPNTSKEISLVPKDETKGGRTIYFGRHILIEGSDSRLLKDGDIVTLINWGNAKVNIAADSKE-----IQLVLMPKNNDYSNTLKISW--LNNESDVEN--IPLQIVTYQNLLNKSVLTPEDDFELYINKNSKSVTKGVGEPYFMNLKRGNIVQIMRKGFYRVDNDF-------GKDKILFLVELPSGTENIK-----------KPDVNVVKKTEKEVKKEKNANVHSKDSREVKKTEKTKSSNKTTKIADVSSGQKLACKPDKMKKTKL------GLSVSKEIDFSQWYTEVITKSELIDYYTISGCYVIRPHAFSIWEAVQTFFDAEMKKLGIQNCYFPIFVPESALTKEKDHINDFAPEVAWVTRAGSTDLAEPIAIRPTSETVIYPTIAKWIQSHRDLPLKLNQWCNVVRWEFKHPTPFIRTREFLWQEGHTVYADREDAVKEVYQILDLYERIYTELLAIPVVKGTKSEAEKFAGAEFTTTVEGYISACGRGLQGATSHHLGQNFSKMFDIGFEDSATCERKFVFQNSFGISTRVVGALVMVHGDDKGLVLPPRVAPIQVVIIPCGISATTTEEMKLKIYEFSQSLALNLKKRDVRVFLDNRENVTPGWKYNHWEMKGVPLRVEVGPKDLSTSTVTIARRDTGEKTSVSIEIFGKSISETLEQIQISMYGKALQDLSNNTVICEDWDSFINNLNSKKVIYSPFCGDKLCEEEVRKTSTSTHEEVNEKGETVTVVSMGAKTLCIPSFQPKKLQPGEKCIRKNCKNDAKCYALFGRSF 1256          

Query:   66 ILNWKNFSKNILKNND-LKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            I +W  FS   L + D L  ++N LN  ++ RTYLV +SL+ AD  ++ TL  +  +Q  LK +   ++V R++  L+     +++ T  + SG + TV  +K              ++ GKFV L     G V VRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF+ ++KY E+LI+   AY D+T A QMK ERE++T SK R  +VE+NL+ W  MK G++ G   C+R K+DM+SNNGCMRDPT+YRCK + H RTG KY VYPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ I++ L +RKP I +YSRL L NTVLSKRKLT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY AL    + +V V ++D  E +++ V RHPKN ++G K VW++P VF+E  DA  F+E   VTFINWGNI ITKIHKN++  ITS+DAKLNL ++D+KKT K+TW+     +      IP   + Y++LITK VLGKD+DFK ++N+DSK EE ++GD  LK+LKKGDIIQLQR+G+FICD+ Y+     + ++ P +LI IP+G++KE  T G K+K++ +
Sbjct:   78 IDHWLEFSATKLSSCDGLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWDVSGSRATVAPDKK-------------QDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRTESKHRKNSVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVAL--LKKEVVPVNVLDAQEEMKE-VARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWL----AESTHALPIPAVCVTYEHLITKPVLGKDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCREAPCILIYIPDGHTKEMPTSGSKEKTKVE 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKP-KYFTMFGRSY 3758
            KK TRLGLE  KE+N +EWY QVITK E+I+YYD+ GCYIL P +  IWE I++  +  I+  GV+ C FP F+S+++L KEK+HI DF+PEVAWVT +G   L EPIAIRPTSET MYP Y+K ++SHRDLP++ NQWC+VVRWEFKHP PFLR+REFLWQEGH+A++   +A +EV QIL+LYA VYE+LLAIPVV+GRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKM +I FE     G+++F +Q SWG+TTRTIG++VMVHGD+ GLVLPPRVA  QVV++PCG+T   +E++ EA+M KC +   RL  A IRV  DL  + SPG+KFN+WELKGVP+R+E+GP+++ +   V   R  G K +I ++  E  +E+ LE I   +F +A  +L  H  V+ T+ED    L+   +   PFCG+  CED IK ++A +  VE GAPSMGAKSLCIPF   C L  G  C+   C   P K++T+FGRSY
Sbjct: 1009 KKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLEKVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQDVEPGAPSMGAKSLCIPFNPLCELQPGAMCV---CGKNPAKFYTLFGRSY 1512          

Query:   66 ILNWKNFSKN-ILKNNDLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLE-IVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            + +W  FS+  +++  +    L  LN  ++ RTYLV ++L+ AD  ++  L  +  +Q L++    P+NV R+Y+ L+      +   +K  S KK                     ++ GKFV L     G V+VRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHFD ++KY E+LI+   AY D+T A QMK ERE++  SK R+ TV +N++ W  MK GTE G   C+R K+DMNSNNGCMRDPT++RCK + H RTG KY +YPTYDF CPIVDS+EGVTH LRT+EY+DR+EQF+ I+D L +RKP I +YSRL L NTVLSKR+LT+ VNEG VDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APRY+AL  S    V V I D  E +VE  V +HPKN  +GQK VW+ P V +E  DA   +E   VTFINWGN++ITKIH++    I S+DAKLNL ++D+KKT K+TW+     +  +  FIP S + YD+LITK VLGK++DFK ++NR SK+EE ++GD  LK+LKKGD+IQLQR+G++ICDE Y+     + K+ P VLI IP+G++KE  T G K+KS+T+
Sbjct:  128 VSHWMEFSQTKLMQKGEFSTGLQELNHCLSLRTYLVGNALTLADICVFSALEASSEWQALVQKGQTPVNVRRWYSFLEPQLGFWSRTNNKVPSEKK---------------------QDVGKFVELPGAEMGKVIVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVSMLQIKPDQFTYTSDHFDTIMKYAEKLIQEGKAYVDDTPAEQMKSEREQRIESKHRSNTVAKNMEMWEDMKKGTEYGQTCCLRAKIDMNSNNGCMRDPTLFRCKNQPHPRTGSKYNIYPTYDFACPIVDSVEGVTHALRTTEYHDRDEQFYWIIDALGIRKPYIWEYSRLNLNNTVLSKRRLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYSALLKSQ--AVAVNIPDAKEGMVE--VAKHPKNAEVGQKPVWYGPKVLIEGADAETLSEGETVTFINWGNLIITKIHRDQSGKIQSLDAKLNLENKDYKKTTKITWL----AETPKAPFIPTSCVNYDHLITKPVLGKEEDFKQYVNRSSKQEEVMLGDPCLKDLKKGDLIQLQRRGFYICDEPYEPISPHSCKEAPCVLIYIPDGHTKEMPTSGSKEKSKTE 764          

Query: 2220 NQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            + S A +    KK TRLGLE  KE+N  +WY QVITK E+I+YYD+ GCY+L P    IWE I+   +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++   +A EEV QILDLYA VYEDLLAIPVVKGRKTEKEKFAG D+TTT E +I +S RAIQGATSHHLGQNFSKMF+I FE     G +++ +QNSWG++TRTIG + MVH D+ G+VLPPRVA  QV+I+PCG+T   +E++ +A+++KC +   RL   ++R  AD+  + SPG+KFN+WELKGVPIR+E+GP+++ N   V   R NG K++I +++ E  ++E LE IH  ++ +A ++L ++  VA TMED    L +  ++  PFCG+  CED IK V+A +  +E GAPSMGAKSLCIPF+    L    KC+  + +   K++T+FGRSY
Sbjct: 1194 DNSAAGESQGPKKQTRLGLEAKKEENLPDWYSQVITKSEMIEYYDVSGCYVLRPWAFAIWEAIKEFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATYEEAAEEVLQILDLYARVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASSRAIQGATSHHLGQNFSKMFEIVFEDPKTPGLKQYAYQNSWGLSTRTIGAMTMVHADNIGMVLPPRVACVQVIIIPCGITNTLSEEDKDALLKKCDQYLKRLLNVDVRARADVRDNYSPGWKFNHWELKGVPIRLEVGPRDMKNKQFVAVRRDNGEKQTISEDQAETRLKEILEEIHTNLYNRALSDLTSNMVVANTMEDFQKNLEKGRIVQIPFCGEIECEDWIKKVTARDQDLEPGAPSMGAKSLCIPFKPLSELQPSAKCVCEKNAA--KFYTLFGRSY 1708          

Query:   57 SILILNWKNFSKNILKNNDLKV-SLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKAD--SVP--LNVLRYYNHLQTLDEIKTI---LTHKNSSGKKDXXXX-------XXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTAL----------SGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGN-SKERATVGMKQKSQTK 2057
            S+ +LNW  F    L N+  +  ++  L  S+AH T+LV D  S AD  +   L  +E FQ L+ ++  + P    V RYYNHL +++++K +   L+ +     K    +        ++    +   ++++FE GGKF  L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+D + G+LI+RFDDTNP+KE   FE+ IL D+  +G+ +D  S++SDHFDLLI  CE++++   AY DNTD   M+ ERE +  S CR  T ++NL +W  MK GTE GL+ C+R K+DMNSNNG MRDPTIYRCKPE HVRTG KY VYP YDF CP+VDS+EGVTH LRTSEYNDRN+Q+     +L LR P + DYSRLALQNT+LSKRKLT+ V EG VDGWDDPRMPTV GILR GMT EGL++F+LAQG  R++  MEWDK+WAFNKKVIDPIAPR+T L            +   LV VRI  Q EI E SV  HPKNE++G + +  +P V+VE  DA  F E  NVTFINWGN  I KIH+ SE  IT++D +LNL D D+KKT K+TW+P    +       PV+ + YD+L+TK +LGKD+DFK ++NR+SK E+CL+GD +L+NLKKG+IIQLQR+GY+I D  Y+  C  TG + P VLI IPEG  SK          SQ K
Sbjct:   37 SVHVLNWVRFVPAYLMNSKKRSWAMEQLEKSLAHATFLVGDDFSVADLAVLCFLECDEEFQKLVVSEEWNSPKFCQVRRYYNHLSSMEQLKELKAKLSERPKLAVKPAEALEGTCGDNAEADISGKTVAADMRFEMGGKFGELPGAKVGEVVVRFPPEASGYLHIGHAKAALLNQHYRDTFKGRLILRFDDTNPSKEKANFEESILCDLPRIGVKWDVRSHTSDHFDLLINLCEQMLREGKAYVDNTDTETMRTERENRKPSACRENTTQQNLAWWEEMKKGTEFGLKCCVRAKIDMNSNNGAMRDPTIYRCKPESHVRTGTKYNVYPIYDFACPVVDSVEGVTHALRTSEYNDRNDQYAWFCQVLGLRCPMVIDYSRLALQNTILSKRKLTWFVEEGLVDGWDDPRMPTVSGILRRGMTAEGLRQFILAQGSSRSSAQMEWDKIWAFNKKVIDPIAPRFTGLLLDPSVPQPSPSTPIGLVPVRIHGQSEIQEKSVAVHPKNESLGHRKIMVSPLVYVEHADATCFKEGENVTFINWGNCRIVKIHR-SEAYITAVDGELNLQDTDYKKTLKITWLP--ELEGKSPALCPVTCLIYDHLLTKGILGKDEDFKPYVNRNSKVEQCLLGDPDLRNLKKGEIIQLQRRGYYIVDVPYEAKCKATGFESPCVLIQIPEGTMSKTTTDTAGSATSQAK 726          

Query: 2220 NQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESR-DGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLK--TAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCN---------LGDKCINS-ECSMKPKYFTMFGRSY 3758
            +Q E SKK   KK TRL LE +KE  FSEWY Q+ITK EL++YYDI GCYI+ P    +W+ IQ  ++  + A GV+   FP F+SK +L +EK+H++DF+PEVAWVT +GD +L EP+A+RPTSET MYP ++K I+SHRDLPL+ NQW +VVRWEFKHP PFLR+REFLWQEGHTAY+ K DA  EV  IL+LYA VY+DLLA+PV+KGRKTE+EKFAGAD+TTT E YI  +GRAIQGATSHHLGQNFS+MF++ ++    GK  FV+QNSWG+TTRT+G+LVMVHGD +GLVLPPR+A HQ+V+VPCG+T K+++++ E ++     +   LK  +++ RV+ D   H SPG+KFN+WE+KGVP+R+E+GP+E+A  +  L  R+NG+K ++    +   + + LE IH  +F KA  EL AH     +++ L + L+ K L  APFCGD  CE+ I+  SA   VVE GAPSMGAKSLCIPF  P N          G KC N   CS     +T+FGRSY
Sbjct:  838 DQVELSKKEGAKKQTRLALEATKESEFSEWYSQLITKAELLEYYDISGCYIIRPWAYSLWQTIQRFLDERLHAMGVENAYFPMFVSKGALEREKNHVSDFAPEVAWVTKSGDSDLAEPVAVRPTSETIMYPAFAKWIQSHRDLPLRLNQWSNVVRWEFKHPQPFLRTREFLWQEGHTAYAEKPDAEAEVLAILNLYAQVYQDLLAVPVIKGRKTEREKFAGADYTTTIEAYISGTGRAIQGATSHHLGQNFSRMFEVTYDHPVTGKPAFVYQNSWGLTTRTLGVLVMVHGDSKGLVLPPRIAPHQIVVVPCGITNKSSQEDRENLLSYALLVTRTLKKDSSQFRVHCDDRTHVSPGWKFNHWEMKGVPVRLEVGPQEMAKQSTCLVLRHNGIKLTVPLADICARMPQILEDIHNDLFRKATGELAAHVVQVGSLDQLCSALDAKSLALAPFCGDSDCEEIIRRESARNVVVEPGAPSMGAKSLCIPFSCPFNDKLVCGSPAAGTKCFNQPHCSRVATAYTLFGRSY 1363          

Query:   42 LMDQASILILNWKNFSKNILKNN-DLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTI-------LTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQ 2051
            +M+Q  +   +W  FS   L     L  +   L+ ++A RT+LV   L+ AD  ++  L  +  +Q          +V R+Y+ L +      +       +T   +SG+K+                    ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF  + +  E+L++   AY D+T    MK+ERE++  S+ RN +VE+N++ W  MK G+E G   C+R K+DM SNNGCMRDPT+YRCK   H RTG  YK+YPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ +++ L LRKP I +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APR++AL    + +V + I +  E ++++  +HPKN ++G KSVW+ P VFVE  DA  F E   VTFINWGNI+I+KI+K+S   ITS++ +LNL + D+KKT K+TW+     D  +   IP   + Y +LI+K VL KDD+FK+F+N+ SK EE ++GD  LK+LKKGDIIQLQR+G++ICD+ Y+     + K+ P VL+ IP+G++KE  T G K KS+
Sbjct:   71 MMEQTEVD--HWLEFSARRLSGQTGLAPAFGELDAALALRTFLVGRGLTLADLCVWAALKGSGEWQAAQAKPGAFPHVSRWYSFLSSQVPFSEVGSKWASKVTASQTSGEKEKS------------------KDVGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTIQRLAEQLLQEGKAYIDDTPPDVMKQEREQRVESRHRNNSVEKNMQMWEEMKAGSEYGQTCCMRAKIDMGSNNGCMRDPTLYRCKNAPHPRTGSTYKIYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVINALRLRKPYIWEYARLNLNNTVLSKRKLTWFVDQGYVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGGSRSVVNMEWDKIWAFNKKVIDPVAPRFSAL--LKQQVVPISIPEAKEEMKEA-AKHPKNADVGMKSVWYGPKVFVEGADAETFTEGETVTFINWGNIIISKINKDSSGAITSLEGRLNLENTDYKKTTKITWL----TDTPKAPLIPTVCVTYQHLISKPVLSKDDNFKDFINKQSKTEEMMLGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCKESPCVLLYIPDGHTKEMPTAGSKDKSK 721          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KEDN ++WY QVITK E+I+YYD+ GCY+L P    IWE I++  +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA VYE+L+AIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I FE   + G+++F +QNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QV+++PCG+T    E E + ++++C K   RL+  ++RV ADL  + SPG+KFN+WELKGVPIR+E+GPK+L     V   R  G K  +    +E  +++ LE I E +F +A  +L  H   A TM+     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF+    L  G  CI+ +     +++T+FGRSY
Sbjct: 1085 KKQTRLGLEAKKEDNLADWYSQVITKSEMIEYYDVSGCYVLRPWAFSIWESIKDFFDKEIKKLGVENCYFPMFVSQAALEKEKSHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEAAEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIIFEDPKKPGEKQFAYQNSWGLTTRTIGVLTMVHGDNMGLVLPPRVACLQVIVIPCGITASLPESEKDLLLDQCSKYLSRLQKIDVRVKADLRDNYSPGWKFNHWELKGVPIRLEVGPKDLKQGQCVAVRRDTGEKLVLPGGTVETRIKQLLEDIQENLFKRASADLKEHMVAADTMDQFQKDLDQGKIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFQPLKTLKEGQMCISGKEPA--QFYTLFGRSY 1588          

Query:   42 LMDQASILILNWKNFSKNILKNN-DLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQT---LDEIKT-----ILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQ 2051
            +M+Q  +   +W  FS   L     L  +   L+ ++A RT+LV   L+ AD  ++  L  +  +Q          +V R+Y+ L +     E+ +     +   + +SG+K+                    ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF  + +  E+L++   AY D+T    MK+ERE++  S+ RN +VE+N++ W  MK G+E G   C+R K+DM SNNGCMRDPT+YRCK   H RTG  YK+YPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ +++ L LRKP I +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFNKKVIDP+APR++AL    + +V + I +  E ++++  +HPKN ++G KSVW+ P VFVE  DA  F E   VTFINWGNI+I+KI+K+S   ITS++ +LNL + D+KKT K+TW+     D  +   IP   + Y +LI+K VL KDD+FK+F+N+ SK EE ++GD  LK+LKKGDIIQLQR+G++ICD+ Y+     + K+ P VL+ IP+G++KE  T G K KS+
Sbjct:   71 MMEQTEVD--HWLEFSARRLSGQTGLAPAFGELDAALALRTFLVGRGLTLADLCVWAALKGSGEWQAAQAKPGAFPHVSRWYSFLSSQVPFSEVGSKWASKVTASQTASGEKEKS------------------KDVGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTIQRLAEQLLQEGKAYIDDTPPDVMKQEREQRVESRHRNNSVEKNMQMWEEMKAGSEYGQTCCMRAKIDMGSNNGCMRDPTLYRCKNAPHPRTGSTYKIYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVINALRLRKPYIWEYARLNLNNTVLSKRKLTWFVDQGYVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGGSRSVVNMEWDKIWAFNKKVIDPVAPRFSAL--LKQQVVPISIPEAKEEMKEA-AKHPKNADVGMKSVWYGPKVFVEGADAETFTEGETVTFINWGNIIISKINKDSSGAITSLEGRLNLENTDYKKTTKITWL----TDTPKAPLIPTVCVTYQHLISKPVLSKDDNFKDFINKQSKTEEMMLGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCKESPCVLLYIPDGHTKEMPTAGSKDKSK 722          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KEDN ++WY QVITK E+I+YYD+ GCY+L P    IWE I++  +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA VYE+L+AIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I FE   + G+++F +QNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QV+++PCG+T    E E + ++++C K   RL+  ++RV ADL  + SPG+KFN+WELKGVPIR+E+GPK+L     V   R  G K  +    +E  +++ LE I E +F +A  +L  H   A TM+     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF+    L  G  CI+ +     +++T+FGRSY
Sbjct: 1174 KKQTRLGLEAKKEDNLADWYSQVITKSEMIEYYDVSGCYVLRPWAFSIWESIKDFFDKEIKKLGVENCYFPMFVSQAALEKEKSHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEAAEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIIFEDPKKPGEKQFAYQNSWGLTTRTIGVLTMVHGDNMGLVLPPRVACLQVIVIPCGITASLPESEKDLLLDQCSKYLSRLQKIDVRVKADLRDNYSPGWKFNHWELKGVPIRLEVGPKDLKQGQCVAVRRDTGEKLVLPGGTVETRIKQLLEDIQENLFKRASADLKEHMVAADTMDQFQKDLDQGKIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFQPLKTLKEGQMCISGKEPA--QFYTLFGRSY 1677          

Query:   42 LMDQASILILNWKNFSKNILKNN-DLKVSLNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQT---LDEIKT-----ILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFN-------KKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQ 2051
            +M+Q  +   +W  FS   L     L  +   L+ ++A RT+LV   L+ AD  ++  L  +  +Q          +V R+Y+ L +     E+ +     +   + +SG+K+                    ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+ ++ GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+Y+SDHF  + +  E+L++   AY D+T    MK+ERE++  S+ RN +VE+N++ W  MK G+E G   C+R K+DM SNNGCMRDPT+YRCK   H RTG  YK+YPTYDF CPIVDSIEGVTH LRT+EY+DR+EQF+ +++ L LRKP I +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+WAFN       KKVIDP+APR++AL    + +V + I +  E ++++  +HPKN ++G KSVW+ P VFVE  DA  F E   VTFINWGNI+I+KI+K+S   ITS++ +LNL + D+KKT K+TW+     D  +   IP   + Y +LI+K VL KDD+FK+F+N+ SK EE ++GD  LK+LKKGDIIQLQR+G++ICD+ Y+     + K+ P VL+ IP+G++KE  T G K KS+
Sbjct:   71 MMEQTEVD--HWLEFSARRLSGQTGLAPAFGELDAALALRTFLVGRGLTLADLCVWAALKGSGEWQAAQAKPGAFPHVSRWYSFLSSQVPFSEVGSKWASKVTASQTASGEKEKS------------------KDVGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTIQRLAEQLLQEGKAYIDDTPPDVMKQEREQRVESRHRNNSVEKNMQMWEEMKAGSEYGQTCCMRAKIDMGSNNGCMRDPTLYRCKNAPHPRTGSTYKIYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVINALRLRKPYIWEYARLNLNNTVLSKRKLTWFVDQGYVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGGSRSVVNMEWDKIWAFNKKLPVSCKKVIDPVAPRFSAL--LKQQVVPISIPEAKEEMKEA-AKHPKNADVGMKSVWYGPKVFVEGADAETFTEGETVTFINWGNIIISKINKDSSGAITSLEGRLNLENTDYKKTTKITWL----TDTPKAPLIPTVCVTYQHLISKPVLSKDDNFKDFINKQSKTEEMMLGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCKESPCVLLYIPDGHTKEMPTAGSKDKSK 729          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KEDN ++WY QVITK E+I+YYD+ GCY+L P    IWE I++  +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC+VVRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA VYE+L+AIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I FE   + G+++F +QNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QV+++PCG+T    E E + ++++C K   RL+  ++RV ADL  + SPG+KFN+WELKGVPIR+E+GPK+L     V   R  G K  +    +E  +++ LE I E +F +A  +L  H   A TM+     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF+    L  G  CI+ +     +++T+FGRSY
Sbjct: 1181 KKQTRLGLEAKKEDNLADWYSQVITKSEMIEYYDVSGCYVLRPWAFSIWESIKDFFDKEIKKLGVENCYFPMFVSQAALEKEKSHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEAAEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIIFEDPKKPGEKQFAYQNSWGLTTRTIGVLTMVHGDNMGLVLPPRVACLQVIVIPCGITASLPESEKDLLLDQCSKYLSRLQKIDVRVKADLRDNYSPGWKFNHWELKGVPIRLEVGPKDLKQGQCVAVRRDTGEKLVLPGGTVETRIKQLLEDIQENLFKRASADLKEHMVAADTMDQFQKDLDQGKIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFQPLKTLKEGQMCISGKEPA--QFYTLFGRSY 1684          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAE--------NTNVTFINWGNIL-ITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNL-ITKNVLGKDDDFKNFL---NRDS-KREECLIGDVELKNLKKGDIIQLQRKGYFICDEE 1940
            + G V  RFPPE +G LHIGHAKA   N  Y     G   +R+DDTNP KE E++   I + V+ LG +    +++SD+F  L +   ELI+  +AY  +    ++K        S  R++ +EE+L  +  MKNG     +  +R+KM M   +G M DP  YR K   H R+G  + +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L  TV+SKRK+  +V  G V  WDDPR+ T+  + R G   + +  F    G   A   ME   L A  ++V++  APR  A+    +  V +  +      E  +   P +E  G   V F+ T+++E+ D  +  E        + +V   + G I+ + ++ K+    +  ++     SD   K    + W+  PL    R+           Y+ L + KN     +    FL   N +S +  E  + D  +   K  D  Q +R GYF  D +
Sbjct:  239 TGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRYDDTNPEKEEEKYFTAIKDMVEWLGYTPYAITHASDNFQCLYELAVELIRRGHAYICHQRGEELKGHNAPP--SPWRDRPIEESLVLFERMKNGMFAEGEATLRMKMVME--DGKM-DPVAYRIKYTPHHRSGDAWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLTYTVVSKRKIIKLVETGTVRDWDDPRLFTLTALRRRGFPPQAINNFCARVGVTVAQTTMEPHLLEACVREVLNDTAPRIMAVLEPLK--VTITNLPANAQTEVRIPDFPADETKGSHVVPFSKTIYIEQSDFREVMEKGYKRLTPDQSVGLRHAGYIISVQRVIKDGSGKVVELEVTCATSDSAEKPKAFIHWVSQPLKCEVRL-----------YERLFLHKNPEDSAEVPGGFLSDINPNSLQVVESALVDRSVSKAKVFDKFQFERVGYFSVDPD 733          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAE--------NTNVTFINWGNIL-ITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNL-ITKNVLGKDDDFKNFL---NRDS-KREECLIGDVELKNLKKGDIIQLQRKGYFICDEE 1940
            + G V  RFPPE +G LHIGHAKA   N  Y     G   +R+DDTNP KE E++   I + V+ LG +    +++SD+F  L +   ELI+  +AY  +    ++K        S  R++ +EE+L  +  MKNG     +  +R+KM M   +G M DP  YR K   H R+G  + +YPTYD+T  + DSIE +TH+L T E+  R   +F + + L +  P   +Y RL L  TV+SKRK+  +V  G V  WDDPR+ T+  + R G   + +  F    G   A   ME   L A  ++V++  APR  A+    +  V +  +      E  +   P +E  G   V F+ T+++E+ D  +  E        + +V   + G I+ + ++ K+    +  ++     SD   K    + W+  PL    R+           Y+ L + KN     +    FL   N +S +  E  + D  +   K  D  Q +R GYF  D +
Sbjct:  260 TGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRYDDTNPEKEEEKYFTAIKDMVEWLGYTPYAITHASDNFQCLYELAVELIRRGHAYICHQRGEELKGHNAPP--SPWRDRPIEESLVLFERMKNGMFAEGEATLRMKMVME--DGKM-DPVAYRIKYTPHHRSGDAWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLTYTVVSKRKIIKLVETGTVRDWDDPRLFTLTALRRRGFPPQAINNFCARVGVTVAQTTMEPHLLEACVREVLNDTAPRIMAVLEPLK--VTITNLPANAQTEVRIPDFPADETKGSHVVPFSKTIYIEQSDFREVMEKGYKRLTPDQSVGLRHAGYIISVQRVIKDGSGKVVELEVTCATSDSAEKPKAFIHWVSQPLKCEVRL-----------YERLFLHKNPEDSAEVPGGFLSDINPNSLQVVESALVDRSVSKAKVFDKFQFERVGYFSVDPD 754          

Query: 2196 QNENKTVENQSEASKKTELKK-VTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETA-MYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQ 2939
            + E K  E + +  KK E KK V  LG+EV K +NFSEWY QVITK EL++YYD+ GCYIL P    IWE IQ   N  I   GV+ C FP  +S+++L +EK HIADF+PEVAWVT +G  +L EP+AIRPTSETA MYP ++K ++SHRDLP+K NQWCSVVRWEFKHP PFLR+REFLWQEGHTAY+N  DA  EV QILDLYA VYE LLAIPVV+G+KTEKEKFAGAD+TTT E +I +SGRAIQ
Sbjct:   71 KQEPKKQEPKKQEPKKQEPKKEVLPLGMEVKKLENFSEWYSQVITKSELVEYYDVSGCYILRPWAYSIWEAIQQFFNAEIMKLGVENCYFPMLVSQAALEREKSHIADFAPEVAWVTRSGKTDLAEPVAIRPTSETAVMYPAFAKWVQSHRDLPIKLNQWCSVVRWEFKHPQPFLRTREFLWQEGHTAYANAKDAKIEVRQILDLYADVYEKLLAIPVVRGQKTEKEKFAGADYTTTVEAFISASGRAIQ 320          

Query: 3129 QVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNLGDK----CINSECSMKPKYFTMFGRSY 3758
            QVVI+ CG+T+   E E +A+ EKC++   RL+ A +R  AD   + SPG+KFN+WELKGVP+R+E+GP+++ N   V   R +G K    +E+   F++E LE I  +++ KA  +L +H  VA +M +L   +++  +   PFC +  CED IK ++A +A VE GAPSMGAKSLCIPF     + D     C+   C+   K +T+FGRSY
Sbjct:    1 QVVIISCGVTVNLAEGERKALYEKCEEYLRRLRDAGVRARADTRDNYSPGWKFNHWELKGVPVRVELGPRDVRNCEFVAVRRDSGEKLVRKEEQAVDFIKELLENIQSSLYAKASTDLHSHMVVADSMAELQKAIDQGKVAQVPFCLEMDCEDEIKKITARDADVEPGAPSMGAKSLCIPFNPLKKMDDASKPPCVG--CNKPAKAYTLFGRSY 212          

Query: 2250 LKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFES---RDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEG-----APSMGAKSLCIPFEQPC-NLGDKCINSECSMKPKYFTMFGRSY 3758
            L+    +G+ V K  +F  WY Q++TKGE++DYYD+ GCYIL P +  IWE IQ   +  I+A GV+   FP F+S   L KEKDH+  F+PEVAWVT AG   LEEPIAIRPTSET MYP+Y+K ++S+RDLPLK NQW SVVRWEFKHP PFLR+REFLWQEGHTA+    DA EEV QILD YA VYE+LLA+PVVKGRKTEKEKFAG DFTTT E YI  +GR IQGATSHHLGQNFSKMF++  E+    D  + F +QNSWG++TR IG++VM+H D++GLV+PPRV++ Q V++P G+T K +E++ + + E  + +  RLK   IR + D + + +PG+KF+ +ELKG+PIRIE+GPK++  N VV+  R +  K  +  + LE  + E LE +   +F KAK   D HR +       +  LN+K +I AP+CG   CE+ IK  SA +   EE      APSMGAKSLCIPF+QP  N G KCI  +C      + MFGRSY
Sbjct:  179 LEDAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCYILRPPSYAIWENIQKWFDDKIKAIGVQNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPYYAKWVQSYRDLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHTAHLTAKDAEEEVLQILDFYAGVYEELLAVPVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPLGSDHPKIFAYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQRKHIHETARSVESRLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQVVVVRRNDSKKYVVSFDELEARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVMECEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPFDQPVLNEGQKCI--KCERIAVNYCMFGRSY 688          

Query:   66 ILNWKNFSKN--ILKN-NDLKVSLNYLNDSIAHRTYLVND-SLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEI---------KTILTHKNSS--GKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLK-YWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQ-KVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNS 2012
            +  W N ++   ++KN   L  SL  L+  +  RT+++     S AD   +  L +N    +++K + V +NV R+Y  L+ +D I         K++L  K S+  GKK             K T    FE     + L +   G VV RFPPE SGYLHIGHAKAAL+NQ++   Y GKLI+RFDDTNP+KE EEF+  ILED+  LG+  D  +YSSD+F  +  YC ++IK   AY D+T   +M++ER +   S  R+++VEENL+ +   MKNGTEEGL+ C+R K+D  + N  +RDP IYRC    H RTG  +K+YPTYDF  PIVD+IEGVTH LRT EY DRN Q+  +L  L LRK  I D++R+    T+LSKRKL ++V++  V  WDDPR PTVRG+ R GMT+EGL+ FVL+QG  R  + +EW+ +WAFNKKVIDPIAPR+TA+    +  +      Q   +E    +H KN  +G+K V +   + V++DDA     +  VT ++WGN++ITK  KN +    S+ AKLNL + DFKKT+ K+TW+    +       +PV  + +D+LITK+ L +D+ F++FL   ++     I D+ +K++K GDIIQ +RKGY+  D   K+     GK  P V   IP+G S
Sbjct:   75 VAKWVNLAQKELVIKNFAKLSQSLETLDSQLNLRTFILGGLKYSAADVACWGALRSNGMCGSIIK-NKVDVNVSRWYTLLE-MDPIFGEAHDFLSKSLLELKKSANVGKK-------------KETHKANFE-----IDLPDAKMGEVVTRFPPEPSGYLHIGHAKAALLNQYFAQAYKGKLIIRFDDTNPSKEKEEFQDSILEDLDLLGIKGDRITYSSDYFQEMYDYCVQMIKDGKAYCDDTPTEKMREERMDGVASARRDRSVEENLRIFTEEMKNGTEEGLKNCVRAKIDYKALNKTLRDPVIYRCNLTPHHRTGSTWKIYPTYDFCVPIVDAIEGVTHALRTIEYRDRNAQYDWMLQALRLRKVHIWDFARINFVRTLLSKRKLQWMVDKDLVGNWDDPRFPTVRGVRRRGMTVEGLRNFVLSQGPSRNVINLEWNLIWAFNKKVIDPIAPRHTAIVNPVKIHLEGSEAPQEPKIE-MKPKHKKNPAVGEKKVIYYKDIVVDKDDADVINVDEEVTLMDWGNVIITK--KNDDG---SMVAKLNL-EGDFKKTKHKLTWLADTKD------VVPVDLVDFDHLITKDRLEEDESFEDFLTPQTEFHTDAIADLNVKDMKIGDIIQFERKGYYRLDALPKD-----GK--PYVFFTIPDGKS 700          

Query:  456 GNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKERE---------EKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVED----------SVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTN 1574
            G V  RFPPE +GYLHIGH+KA ++N  Y  ++ G   +RFDDTNP KE  E+ + I   V  LG      +YSSD+FD L +  E LIK+  AY  +  A ++K+ R          E+   K R+Q++E+NL+ +  M++G  +  +  +R+K D+NS +  M D   YR     H RTG K+++YPTYDFT  +VDS+E +TH+L T+E+    E +  + D + + +P   +Y RL +  TVLSKRK+  +V+E +V GWDDPR+ T+  I R G+    +  F+   G   +   ++  +  +  +K ++   PR            L+ ++D +E+V D          ++   P     G+++V FT   ++ER    DF+EN +
Sbjct:  250 GKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPR------------LMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERS---DFSENVD 626          

Query:  462 VVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLI-KYCEELIKSENAYA---------DNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPT---IYRCKPEFHVRTGYKYKVY-----------PTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTV----LSKRKLTF--------------IVNEGYVDGWDDPR 1232
            V  RF P  +G+LH+G  + AL N     +  G+ ++R +DT+  +  E  E+ I E +K   ++YD          L+  KY + L+ S  AY          D   +    K     +  +C     EE +      K+   +G+ + +R K          R PT   +   +     +  +  K Y           PTY     + D + G+TH +R  E+     +   + +      P+   +  + L  TV    LSKRK                 ++N   + GW  PR
Sbjct:   45 VRTRFAPSPTGFLHLGSLRTALYNYLLARNTNGQFLLRLEDTDQKRLIEGAEENIYEILKWCNINYDETPIKQSERKLIYDKYVKILLSSGKAYRCFCSKERLNDLRHSAMELKPPSMASYDRCCAHLGEEEI------KSKLAQGIPFTVRFK-------SPERYPTFTDLLHGQINLQPQVNFNDKRYDDLILVKSDKLPTYHLANVVDDHLMGITHVIRGEEWLPSTPKHIALYNAFGWACPK---FIHIPLLTTVGDKKLSKRKGDMSISDLKRQGVLPEALINFCALFGWSPPR 327          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAEN--------TNVTFINWGNIL-ITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLIT-KNVLGKDDDFKNFLNRDSKREECLIG----DVELKNLKKGDIIQLQRKGYFICDEEYKEN 1952
            +KG V  RFPPE +G LHIGHAKA  IN  Y   + G   +R+DDTNP KE E+F   IL+ VK LG      +++SD+FD L +Y  ELIK  +AY  +    ++K        S  R + +EE+L+ +  MK G  +  Q  +R+K  +        DP  YR K   H R+G K+ +YPTYDFT  + DSIE +TH+L T E+  R   ++ + + L +  P   +Y RL L  TV+SKRK+  ++NEG V  WDDPR+ T+  + R G   E + +F    G   A  V++   L A  +  ++  A R  A+    +  +     D+  ++E  V   P + + G   V F   +++E  D  +  E          +V   + G ++ + K+ KN+   ++ ++    L+    K    + W        +    +P     YD L   KN    ++    F++  +K    +I     D+  K        Q +R+GYF  D +  +N
Sbjct:  260 TKGRVQTRFPPEPNGILHIGHAKAININFGYAKAHNGVCYLRYDDTNPEKEEEKFFTGILDMVKWLGFEPWKITHASDNFDKLYEYAVELIKRGDAYVCHQQYEEIKGYNPPP--SPWRERPIEESLRLFEDMKKGKLDEGQATLRMKTTLEDGKA---DPVAYRIKFTPHHRSGDKWCIYPTYDFTHCLCDSIEDITHSLCTKEFQSRRSSYYWLCNALDIYCPVQWEYGRLNLSYTVVSKRKIGKLINEGIVRNWDDPRLFTLTALRRRGFPAEAINKFCSKVGVTMAQTVIDPLMLEACVRDELNLTATRVMAVLEPLKVTITNFPSDKAMMIE--VPNLPMDASKGNHKVPFDRVLYIESSDFRETMEKGYRRLTPEQSVGLRHAGYVIKVKKVIKNASGEVSELEVTCELTSSTDKPKAFIHW--------VASTAVPCEIRLYDRLFKHKNPEDPEEVPGGFVSDCNKDSLTVIPNALVDITAKGAAPFTKFQFERQGYFCVDPDSSKN 759          

Query: 1695 KVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEG 2006
            K+TW+     D      IP   + +DNLI+K ++ K DDFK F+N++SK E  L G+ EL ++KKGD+IQLQR+G+FICD+ Y+          P VL ++P+G
Sbjct:    1 KLTWL----ADTPTAPTIPAVMVNFDNLISKGIITKTDDFKQFVNKNSKTEVILAGEPELASVKKGDVIQLQRRGFFICDQPYEPT-------SPCVLFSVPDG 93          

Query: 3237 IRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMF 3461
            IR   D + H SPG+KFN+WELKGVPIRIE+GP+++ NN  VL  R++  K +I  E     ++E LE I   MF
Sbjct:  156 IRAKGDFNEHHSPGWKFNHWELKGVPIRIEVGPRDVKNNKFVLVRRHDRSKHTIQHEGFVGSIQETLEVIQNEMF 230          

Query:   72 NWKNFSKNILKNNDLKVS-LNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            +W  FS   L +     S L  L+ +++ RT+LV   L+ AD +++  L    +     K  S+P +V R+++ L +      +  +K +S K +                + + ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+++SDHF  +++  E+L+    AY DNT   QMK+ERE++  SKCR+ TVE+N+K W  MK GTE G   C+R K+DMNSNNGC+RDP +YRCK   H RTG  YKVYPTYDF CPIVDS+EGVTH LRT+EY+DR++QF+ I++ L LRKP + +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+W+FNKKVIDP+APR+TALSGS   +V V I +  E +++ V +HPKN  +G K VW+ P V VE  DA  F E   VTFINWGN++ITKI+K ++  + S++A+LNL ++DFKKT K+TW+     D      +P   + Y  LI+K VLGKDDDFK ++N+++K EE ++GD  LK+LKKGDIIQLQR+G++ICD+ Y+     + K+ P VLI IP+G++KE  T G K KS+++
Sbjct:   79 HWLEFSARRLADPSSSTSALAELDKALSLRTFLVGHGLTLADLSVWAALKATNDLSG--KGGSLP-HVSRWFSFLSSQVPFSAV-GNKFASKKPEPKTTNS----------DKKKQDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIQPDQFTFTSDHFPTIMRMAEKLLAEGKAYIDNTPPEQMKQEREQRIESKCRSNTVEQNMKMWEEMKAGTEYGQTCCMRAKIDMNSNNGCLRDPALYRCKNAPHPRTGDTYKVYPTYDFACPIVDSLEGVTHALRTTEYHDRDDQFYWIINALQLRKPHVWEYARLNLNNTVLSKRKLTWFVDQGYVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGGSRSVVNMEWDKIWSFNKKVIDPVAPRFTALSGS--YVVPVSIPEAKEEMKE-VAKHPKNPEVGVKEVWYGPKVLVEGADAETFKEGEVVTFINWGNLIITKINKGADGKVASLEARLNLDNKDFKKTTKITWL----ADTTSAPTMPAVCVSYQPLISKAVLGKDDDFKQYINKNTKMEEKMVGDPCLKSLKKGDIIQLQRRGFYICDQPYEPISPNSCKESPCVLIYIPDGHTKEMPTAGSKDKSKSQ 720          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+YYD+ GCY+L P +  IWE I++  +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC++VRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA +YE+LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I FE   R G+++  FQNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QVVI+PCG+T    EQE EA++ +C K   RL  A +RV +D   + SPG+KFN+WELKGVP+R+E+GPK++     V   R  G K ++ +  +E+ +   LE I  ++F KA ++L +H   A TME     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF     L  G  C++ + +   +Y+T+FGRSY
Sbjct: 1164 KKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWEAIKDFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNIVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVMQILDLYARIYEELLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVFEDPKRPGEKQLAFQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACVQVVIIPCGITASLPEQEKEALLAQCSKYLKRLLDAGVRVKSDFRDNYSPGWKFNHWELKGVPVRLEVGPKDMQQKQCVAVRRDTGAKITLPEGEVEKRLVAMLEEIQGSLFKKASDDLRSHMVTADTMEQFQKELDQGRIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFSPLKTLQPGQMCVSGKEAA--QYYTLFGRSY 1667          

Query:   72 NWKNFSKNILKNNDLKVS-LNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            +W  FS   L +     S L  L+ +++ RT+LV   L+ AD +++  L    +     K  S+P +V R+++ L +      +    +   K+D                       GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+++SDHF  +++  E+L+    AY DNT   QMK+ERE++  SKCR+ TVE+N+K W  MK GTE G   C+R K+DMNSNNGC+RDP +YRCK   H RTG  YKVYPTYDF CPIVDS+EGVTH LRT+EY+DR++QF+ I++ L LRKP + +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+W+FNKKVIDP+APR+TALSGS   +V V I +  E +++ V +HPKN  +G K VW+ P V VE  DA  F E   VTFINWGN++ITKI+K ++  + S++A+LNL ++DFKKT K+TW+     D      +P   + Y  LI+K VLGKDDDFK ++N+++K EE ++GD  LK+LKKGDIIQLQR+G++ICD+ Y+     + K+ P VLI IP+G++KE  T G K KS+++
Sbjct:   80 HWLEFSARRLADPSSSTSALAELDKALSLRTFLVGHGLTLADLSVWAALKATNDLSG--KGGSLP-HVSRWFSFLSSQVPFSAVGNKFSDKKKQDL----------------------GKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIQPDQFTFTSDHFPTIMRMAEKLLAEGKAYIDNTPPEQMKQEREQRIESKCRSNTVEQNMKMWEEMKAGTEYGQTCCMRAKIDMNSNNGCLRDPALYRCKNAPHPRTGDTYKVYPTYDFACPIVDSLEGVTHALRTTEYHDRDDQFYWIINALQLRKPHVWEYARLNLNNTVLSKRKLTWFVDQGYVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGGSRSVVNMEWDKIWSFNKKVIDPVAPRFTALSGS--YVVPVSIPEAKEEMKE-VAKHPKNPEVGVKEVWYGPKVLVEGADAETFKEGEVVTFINWGNLIITKINKGADGKVASLEARLNLDNKDFKKTTKITWL----ADTTSAPTMPAVCVSYQPLISKAVLGKDDDFKQYINKNTKMEEKMVGDPCLKSLKKGDIIQLQRRGFYICDQPYEPISPNSCKESPCVLIYIPDGHTKEMPTAGSKDKSKSQ 710          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+YYD+ GCY+L P +  IWE I++  +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC++VRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA +YE+LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I FE   R G+++  FQNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QVVI+PCG+T    EQE EA++ +C K   RL  A +RV +D   + SPG+KFN+WELKGVP+R+E+GPK++     V   R  G K ++ +  +E+ +   LE I  ++F KA ++L +H   A TME     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF     L  G  C++ + +   +Y+T+FGRSY
Sbjct:  995 KKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWEAIKDFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNIVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVMQILDLYARIYEELLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVFEDPKRPGEKQLAFQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACVQVVIIPCGITASLPEQEKEALLAQCSKYLKRLLDAGVRVKSDFRDNYSPGWKFNHWELKGVPVRLEVGPKDMQQKQCVAVRRDTGAKITLPEGEVEKRLVAMLEEIQGSLFKKASDDLRSHMVTADTMEQFQKELDQGRIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFSPLKTLQPGQMCVSGKEAA--QYYTLFGRSY 1498          

Query:   72 NWKNFSKNILKNNDLKVS-LNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNK-------KVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            +W  FS   L +     S L  L+ +++ RT+LV   L+ AD +++  L    +     K  S+P +V R+++ L +      +  +K +S K +                + + ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+++SDHF  +++  E+L+    AY DNT   QMK+ERE++  SKCR+ TVE+N+K W  MK GTE G   C+R K+DMNSNNGC+RDP +YRCK   H RTG  YKVYPTYDF CPIVDS+EGVTH LRT+EY+DR++QF+ I++ L LRKP + +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+W+FNK       KVIDP+APR+TALSGS   +V V I +  E +++ V +HPKN  +G K VW+ P V VE  DA  F E   VTFINWGN++ITKI+K ++  + S++A+LNL ++DFKKT K+TW+     D      +P   + Y  LI+K VLGKDDDFK ++N+++K EE ++GD  LK+LKKGDIIQLQR+G++ICD+ Y+     + K+ P VLI IP+G++KE  T G K KS+++
Sbjct:   79 HWLEFSARRLADPSSSTSALAELDKALSLRTFLVGHGLTLADLSVWAALKATNDLSG--KGGSLP-HVSRWFSFLSSQVPFSAV-GNKFASKKPEPKTTNS----------DKKKQDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIQPDQFTFTSDHFPTIMRMAEKLLAEGKAYIDNTPPEQMKQEREQRIESKCRSNTVEQNMKMWEEMKAGTEYGQTCCMRAKIDMNSNNGCLRDPALYRCKNAPHPRTGDTYKVYPTYDFACPIVDSLEGVTHALRTTEYHDRDDQFYWIINALQLRKPHVWEYARLNLNNTVLSKRKLTWFVDQGYVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGGSRSVVNMEWDKIWSFNKKLPVSCLKVIDPVAPRFTALSGS--YVVPVSIPEAKEEMKE-VAKHPKNPEVGVKEVWYGPKVLVEGADAETFKEGEVVTFINWGNLIITKINKGADGKVASLEARLNLDNKDFKKTTKITWL----ADTTSAPTMPAVCVSYQPLISKAVLGKDDDFKQYINKNTKMEEKMVGDPCLKSLKKGDIIQLQRRGFYICDQPYEPISPNSCKESPCVLIYIPDGHTKEMPTAGSKDKSKSQ 727          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+YYD+ GCY+L P +  IWE I++  +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC++VRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA +YE+LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I FE   R G+++  FQNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QVVI+PCG+T    EQE EA++ +C K   RL  A +RV +D   + SPG+KFN+WELKGVP+R+E+GPK++     V   R  G K ++ +  +E+ +   LE I  ++F KA ++L +H   A TME     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF     L  G  C++ + +   +Y+T+FGRSY
Sbjct: 1088 KKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWEAIKDFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNIVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVMQILDLYARIYEELLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVFEDPKRPGEKQLAFQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACVQVVIIPCGITASLPEQEKEALLAQCSKYLKRLLDAGVRVKSDFRDNYSPGWKFNHWELKGVPVRLEVGPKDMQQKQCVAVRRDTGAKITLPEGEVEKRLVAMLEEIQGSLFKKASDDLRSHMVTADTMEQFQKELDQGRIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFSPLKTLQPGQMCVSGKEAA--QYYTLFGRSY 1591          

Query:   72 NWKNFSKNILKNNDLKVS-LNYLNDSIAHRTYLVNDSLSDADKNIYLTLYNNENFQNLLKADSVPLNVLRYYNHLQTLDEIKTILTHKNSSGKKDXXXXXXXXXXXXXXXXNVQFEEGGKFVGLKNGSKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNK-------KVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTK 2057
            +W  FS   L +     S L  L+ +++ RT+LV   L+ AD +++  L    +     K  S+P +V R+++ L +      +  +K +S K +                + + ++ GKFV L     G VVVRFPPEASGYLHIGHAKAAL+NQHY+  + GKLIMRFDDTNP KE E+FEK+ILEDV  L +  D F+++SDHF  +++  E+L+    AY DNT   QMK+ERE++  SKCR+ TVE+N+K W  MK GTE G   C+R K+DMNSNNGC+RDP +YRCK   H RTG  YKVYPTYDF CPIVDS+EGVTH LRT+EY+DR++QF+ I++ L LRKP + +Y+RL L NTVLSKRKLT+ V++GYVDGWDDPR PTVRG+LR GMT+EGLK+F+ AQG  R+ V MEWDK+W+FNK       KVIDP+APR+TALSGS   +V V I +  E +++ V +HPKN  +G K VW+ P V VE  DA  F E   VTFINWGN++ITKI+K ++  + S++A+LNL ++DFKKT K+TW+     D      +P   + Y  LI+K VLGKDDDFK ++N+++K EE ++GD  LK+LKKGDIIQLQR+G++ICD+ Y+     + K+ P VLI IP+G++KE  T G K KS+++
Sbjct:   79 HWLEFSARRLADPSSSTSALAELDKALSLRTFLVGHGLTLADLSVWAALKATNDLSG--KGGSLP-HVSRWFSFLSSQVPFSAV-GNKFASKKPEPKTTNS----------DKKKQDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIQPDQFTFTSDHFPTIMRMAEKLLAEGKAYIDNTPPEQMKQEREQRIESKCRSNTVEQNMKMWEEMKAGTEYGQTCCMRAKIDMNSNNGCLRDPALYRCKNAPHPRTGDTYKVYPTYDFACPIVDSLEGVTHALRTTEYHDRDDQFYWIINALQLRKPHVWEYARLNLNNTVLSKRKLTWFVDQGYVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGGSRSVVNMEWDKIWSFNKKLPVSCLKVIDPVAPRFTALSGS--YVVPVSIPEAKEEMKE-VAKHPKNPEVGVKEVWYGPKVLVEGADAETFKEGEVVTFINWGNLIITKINKGADGKVASLEARLNLDNKDFKKTTKITWL----ADTTSAPTMPAVCVSYQPLISKAVLGKDDDFKQYINKNTKMEEKMVGDPCLKSLKKGDIIQLQRRGFYICDQPYEPISPNSCKESPCVLIYIPDGHTKEMPTAGSKDKSKSQ 727          

Query: 2253 KKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFE--SRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNL--GDKCINSECSMKPKYFTMFGRSY 3758
            KK TRLGLE  KE+N ++WY QVITK E+I+YYD+ GCY+L P +  IWE I++  +  I+  GV+ C FP F+S+++L KEK HIADF+PEVAWVT +G   L EPIA+RPTSET MYP Y+K ++SHRDLP+K NQWC++VRWEFKHP PFLR+REFLWQEGHTA++ K +A EEV QILDLYA +YE+LLAIPVVKGRKTEKEKFAG D+TTT E +I +SGRAIQGATSHHLGQNFSKMF+I FE   R G+++  FQNSWG+TTRTIG+L MVHGD+ GLVLPPRVA  QVVI+PCG+T    EQE EA++ +C K   RL  A +RV +D   + SPG+KFN+WELKGVP+R+E+GPK++     V   R  G K ++ +  +E+ +   LE I  ++F KA ++L +H   A TME     L++  ++  PFCG   CED IK  +A +  +E GAPSMGAKSLCIPF     L  G  C++ + +   +Y+T+FGRSY
Sbjct: 1171 KKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWEAIKDFFDKEIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNIVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVMQILDLYARIYEELLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVFEDPKRPGEKQLAFQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACVQVVIIPCGITASLPEQEKEALLAQCSKYLKRLLDAGVRVKSDFRDNYSPGWKFNHWELKGVPVRLEVGPKDMQQKQCVAVRRDTGAKITLPEGEVEKRLVAMLEEIQGSLFKKASDDLRSHMVTADTMEQFQKELDQGRIVQIPFCGGIECEDWIKKTTAKDQDLEPGAPSMGAKSLCIPFSPLKTLQPGQMCVSGKEAA--QYYTLFGRSY 1674          

Query:  456 GNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAEN--------TNVTFINWGNIL-ITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWM--PLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREEC-----LIGDVELKNLKKGDIIQLQRKGYFICDEEYKEN 1952
            G +  RFPPE +G LHIGHAKA   N  Y     G   +R+DDTNP KE E++   I + V+ LG +    +++SDHF  L     +LI+  +AY  +    ++K        S  R++ +EE+L  +  MK G     +  +R+KM M   +G M DP  YR K   H RTG ++ +YPTYD+T  + DSIE +TH+L T E+  R   ++ + + L L  P   +Y RL L  TV+SKRK+  +V  G V  WDDPR+ T+  + R G   E +  F    G   +    E   L A  + V++  APR  A++  +   V +  + +    +  V   P NE  G  +V FT T+F+E+ D  +  E           V   + G ++ I KI K++E  +  ++     S+   K    + W+  PL    R+           YD L          +  N    D            + D  +K  K  D  Q +R GYF  D +   N
Sbjct:  240 GQIRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRYDDTNPEKEEEKYFTAIKDMVEWLGYTPYDVTHASDHFQKLYDLAVDLIRRGHAYVCHQKGEELKGHNVPP--SPWRDRPIEESLVLFERMKKGLFAEGEATLRMKMVME--DGKM-DPVAYRIKYTPHHRTGDEWCIYPTYDYTHCLCDSIENITHSLCTKEFQARRSSYYWLCNALDLYCPVQWEYGRLNLTYTVVSKRKIIKLVETGVVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVSQTTTEPHLLEACVRDVLNESAPR--AMAVLEPLKVTITNLPENAKSDVRVPDFPANEAKGSHTVPFTRTIFIEQSDFREVMEKGYKRLTPEQPVGLRHAGYVISIQKIIKDAEGKVAELEVTCCSSETAEKPKAFIHWVSKPLACEVRL-----------YDKLFLHKHPEDPSEVPNGFLSDINPHSLEVIRNALVDTSVKTAKVFDKFQFERVGYFSLDPDSTAN 736          

Query:  570 MRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCSITGKQYPLVLINIPEGNSKERATVGMKQKSQTKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLQNENKTVENQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRDGKQEFVFQNSWGMTTRTIGILVMVHGDDRGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQKLADRLKTAEIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNLGDKCINSECSMKPKYFTMFGRSY 3758
            MRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIV+DSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENC ITGKQYPLVLINIPEGNSKERATVGMKQKSQTKPEKSGDDSNSKKDKTSKKEKTEKVENKNKKTEKVENKNKKSEKVELQNENKT ENQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRDGKQEFVFQNSWGMTTRTIGILVMVHGDD+GLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQ+LADRLKTA IRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNLGDKCINSECSMKPKYFTMFGRSY
Sbjct:    1 MRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLVLVRIVDQLEIVQDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTFINWGNILITKIHKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVELKNLKKGDIIQLQRKGYFICDEEYKENCPITGKQYPLVLINIPEGNSKERATVGMKQKSQTKPEKSGDDSNSKKDKTSKKEKTEKVENKNKKTEKVENKNKKSEKVELQNENKTAENQSEASKKTELKKVTRLGLEVSKEDNFSEWYIQVITKGELIDYYDIKGCYILLPETMEIWEKIQNHINTTIRAKGVKACNFPTFISKSSLMKEKDHIADFSPEVAWVTMAGDKNLEEPIAIRPTSETAMYPFYSKRIRSHRDLPLKYNQWCSVVRWEFKHPIPFLRSREFLWQEGHTAYSNKNDAVEEVHQILDLYASVYEDLLAIPVVKGRKTEKEKFAGADFTTTTEVYIGSSGRAIQGATSHHLGQNFSKMFDIRFESRDGKQEFVFQNSWGMTTRTIGILVMVHGDDKGLVLPPRVAEHQVVIVPCGLTIKATEQETEAMMEKCQQLADRLKTAGIRVYADLDPHRSPGFKFNNWELKGVPIRIEMGPKELANNTVVLCYRYNGVKESIMDERLERFVEEKLEAIHEAMFVKAKNELDAHRSVAFTMEDLINGLNRKMLITAPFCGDKACEDRIKIVSAGEAVVEEGAPSMGAKSLCIPFEQPCNLGDKCINSECSMKPKYFTMFGRSY 1063          

Query:  450 SKGNVVVRFPPEASGYLHIGHAKAALINQHYKDHYAGKLIMRFDDTNPAKETEEFEKIILEDVKSLGLSYDHFSYSSDHFDLLIKYCEELIKSENAYADNTDAVQMKKEREEKTISKCRNQTVEENLKYWNLMKNGTEEGLQYCIRIKMDMNSNNGCMRDPTIYRCKPEFHVRTGYKYKVYPTYDFTCPIVDSIEGVTHTLRTSEYNDRNEQFFRILDLLSLRKPEIADYSRLALQNTVLSKRKLTFIVNEGYVDGWDDPRMPTVRGILRHGMTIEGLKEFVLAQGFGRANVVMEWDKLWAFNKKVIDPIAPRYTALSGSDRSLV---LVRIVDQLEIVEDSVGRHPKNENIGQKSVWFTPTVFVERDDAVDFAENTNVTF----------INWGNILITKI---HKNSENVITSIDAKLNLSDRDFKKTQKVTWMPLGSNDRIEDYFIPVSAIFYDNLITKNVLGKDDDFKNFLNRDSKREECLIGDVEL--KNLKKGDI---IQLQRKGYFICDEE 1940
            + G VV RFPPE +G LHIGHAKA   N  Y     G   +R+DDTNP KE E+F   I + V+ LG      +Y+SD+F  L +Y  +LIK   AY  +    +++       +S  R++ +EE+LK +  MKNG  E  +  +R+K+ M        DP  YR K   H RTG  + +YPTYDFT  I DSIE ++H+L + E+  R   ++ + + L +  P   +Y RL +  TV+SKRK+  +V++G V  WDDPR+ T+  + R G   E + +F    G  +   V++   L A  +  ++  APR  A+    + ++      I  QLE+ +      P  E+ G   +  +  +F+ER    DF+E+    +          + +  I+IT       N    + +I+A     D+  K    + W+       I +Y    S +F +    ++  G    +   +NRDS     L+    L  + + K  +    Q +R GYF+ D++
Sbjct:   45 TGGKVVTRFPPEPNGVLHIGHAKAIHFNFGYAKKNNGICYLRYDDTNPEKEEEKFFLAIKDMVEWLGFEPYAVTYASDNFSKLYEYARKLIKVNQAYICHQPLEEIRGF--NPPLSPWRDRPIEESLKIFEDMKNGKIEEGKATLRMKLIMEDGKP---DPVAYRIKFVPHHRTGNDWCIYPTYDFTHCICDSIENISHSLCSKEFQSRRSAYYWLCNALDIYCPVQWEYGRLNMWYTVMSKRKILQLVDKGIVGNWDDPRLFTLTALRRRGFPAESIGDFCEKIGVTQTQTVIDPAMLEACVRNTLNLKAPRTMAVVEPIKIVISNFPDSIPSQLEVFD-----FPGEESRGSHKISTSNVIFIERS---DFSESPMKGYRRLTPEQPVGLRYLGIVITVTSIDRDNQSGAVIAINATCCGVDQCKKPKAFIHWVANPIACEIRNY----SRLFSEKFPEEHPQG----YLACINRDS----LLVNGGALIDRYITKPAVYTRFQFERTGYFVVDQD 537