Homocysteine S-methyltransferase 1-like Protein

Overview
NameHomocysteine S-methyltransferase 1-like Protein
Smed IDSMED30030357
Length (bp)1683
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Homocysteine S-methyltransferase 1-like Protein (SMED30030357) t-SNE clustered cells

Violin plots show distribution of expression levels for Homocysteine S-methyltransferase 1-like Protein (SMED30030357) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Homocysteine S-methyltransferase 1-like Protein (SMED30030357) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Homocysteine S-methyltransferase 1-like Protein (SMED30030357) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030357

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30030357h1SMcG0013979 dd_Smed_v4_9368_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30030357h1SMcG0013979 dd_Smed_v4_9368_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Celegans
Match: T13G4.4 (pep chromosome:WBcel235:X:1188453:1190752:-1 gene:WBGene00020491.1 transcript:T13G4.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T13G4.4)

HSP 1 Score: 75.0998 bits (183), Expect = 1.496e-14
Identity = 60/191 (31.41%), Postives = 87/191 (45.55%), Query Frame = 2 
Query:  347 ASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSL--TRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNR---DKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPL-WIEGGADWIGGCC 901
             S+G       D SEY G Y+D++   +    Y + I +L   R+    L FETIP+  E  + +++++E+P   A IS    +     HGE +  V        S  V+G G NC  P     N V    ++L      ++FV YPN G+      SK+L      +N F + L   WIE G   IGGCC
Sbjct:  105 GSVGTLATMYHDLSEYTGAYMDQSEAKKTAYDYFKIILTLFHNRSSIRKLIFETIPSADEGSVALDVLQEFPEFEAVISFTFKEHGCLRHGEKITSVAQQMK--QSPQVLGIGINCTDP-----NNVLPALNELQPFAFSEVFV-YPNKGD------SKFLEEGIDESNVFTKTLVTSWIEKGVTAIGGCC 281
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Fly
Match: CG10621 (gene:FBgn0032726 transcript:FBtr0081191)

HSP 1 Score: 120.168 bits (300), Expect = 1.186e-29
Identity = 88/282 (31.21%), Postives = 140/282 (49.65%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY--ENKKSLIT-----PILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIM-KEYPNVPAWISVNSCDGMKTAHGENLKGVVDN-FNLFSSENV----IGFGFNC-----VIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQS 949
            F++   ++I + +YQ+S         L  E++ +L+ ++V LA     +Y  E  ++ ++     P++ A SIGPFGAHL DGSEY G Y D     +I +++  +I +   A  D LA ETIP Q E E ++E++  +YP+V  W++    D    AHGE      +  ++L +  N     +  G NC     V PL +  N   ++  Q+      V+YPN+GE+ D  V+ W           Y  +P W + GA  IGGCCR  A  +  + E I+ 
Sbjct:   50 FLQNGADIILTNTYQSSVDGYMEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIA-SIGPFGAHLHDGSEYTGSYADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCKDENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVGEQIP----LVVYPNSGEVYD-VVNGWQGREHCVPLANY--VPEWAQLGAKVIGGCCRTYARDIRHIGEAIRD 323
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Fly
Match: CG10621 (gene:FBgn0032726 transcript:FBtr0342926)

HSP 1 Score: 120.168 bits (300), Expect = 1.186e-29
Identity = 88/282 (31.21%), Postives = 140/282 (49.65%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY--ENKKSLIT-----PILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIM-KEYPNVPAWISVNSCDGMKTAHGENLKGVVDN-FNLFSSENV----IGFGFNC-----VIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQS 949
            F++   ++I + +YQ+S         L  E++ +L+ ++V LA     +Y  E  ++ ++     P++ A SIGPFGAHL DGSEY G Y D     +I +++  +I +   A  D LA ETIP Q E E ++E++  +YP+V  W++    D    AHGE      +  ++L +  N     +  G NC     V PL +  N   ++  Q+      V+YPN+GE+ D  V+ W           Y  +P W + GA  IGGCCR  A  +  + E I+ 
Sbjct:   50 FLQNGADIILTNTYQSSVDGYMEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIA-SIGPFGAHLHDGSEYTGSYADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCKDENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVGEQIP----LVVYPNSGEVYD-VVNGWQGREHCVPLANY--VPEWAQLGAKVIGGCCRTYARDIRHIGEAIRD 323
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Fly
Match: CG10621 (gene:FBgn0032726 transcript:FBtr0342927)

HSP 1 Score: 120.168 bits (300), Expect = 1.186e-29
Identity = 88/282 (31.21%), Postives = 140/282 (49.65%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY--ENKKSLIT-----PILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIM-KEYPNVPAWISVNSCDGMKTAHGENLKGVVDN-FNLFSSENV----IGFGFNC-----VIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQS 949
            F++   ++I + +YQ+S         L  E++ +L+ ++V LA     +Y  E  ++ ++     P++ A SIGPFGAHL DGSEY G Y D     +I +++  +I +   A  D LA ETIP Q E E ++E++  +YP+V  W++    D    AHGE      +  ++L +  N     +  G NC     V PL +  N   ++  Q+      V+YPN+GE+ D  V+ W           Y  +P W + GA  IGGCCR  A  +  + E I+ 
Sbjct:   50 FLQNGADIILTNTYQSSVDGYMEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIA-SIGPFGAHLHDGSEYTGSYADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCKDENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVGEQIP----LVVYPNSGEVYD-VVNGWQGREHCVPLANY--VPEWAQLGAKVIGGCCRTYARDIRHIGEAIRD 323
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Fly
Match: CG10623 (gene:FBgn0032727 transcript:FBtr0344844)

HSP 1 Score: 116.316 bits (290), Expect = 2.285e-28
Identity = 82/281 (29.18%), Postives = 132/281 (46.98%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY------ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIE-IMKEYPNVPAWISVNSCDGMKTAHGENL-KGVVDNFNLFSSEN----VIGFGFNCVIPLLEVKNTVHKIRSQLNRDKI-FVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSHRIK 961
            F++   ++I + +YQ+S         ++ E   +L+  SV LAK    +Y      E + +L    L   SIGP+GA+L DGSEY G Y D+ S  ++R +++ +I     A  D LA ET+P   E E + E ++  +P+   W+S+   D    A GEN  +  +  + L  S      ++G G NCV PL  V   +  +      D+I  V+Y N GE+ D     W            + +P WI+ G   +GGCCR+    +  + + +    IK
Sbjct:   58 FLRNGADIILTNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAESALP---LIMGSIGPYGAYLHDGSEYTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLF-VTPLLSSLTKVAGSDRIPLVVYSNRGEIYDVEQGDWTG----TGEEVVKFVPEWIQLGVRIVGGCCRVYPTDVLAIRKYVDGLNIK 330
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Fly
Match: CG10623 (gene:FBgn0032727 transcript:FBtr0344845)

HSP 1 Score: 116.316 bits (290), Expect = 2.285e-28
Identity = 82/281 (29.18%), Postives = 132/281 (46.98%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY------ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIE-IMKEYPNVPAWISVNSCDGMKTAHGENL-KGVVDNFNLFSSEN----VIGFGFNCVIPLLEVKNTVHKIRSQLNRDKI-FVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSHRIK 961
            F++   ++I + +YQ+S         ++ E   +L+  SV LAK    +Y      E + +L    L   SIGP+GA+L DGSEY G Y D+ S  ++R +++ +I     A  D LA ET+P   E E + E ++  +P+   W+S+   D    A GEN  +  +  + L  S      ++G G NCV PL  V   +  +      D+I  V+Y N GE+ D     W            + +P WI+ G   +GGCCR+    +  + + +    IK
Sbjct:   58 FLRNGADIILTNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAESALP---LIMGSIGPYGAYLHDGSEYTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLF-VTPLLSSLTKVAGSDRIPLVVYSNRGEIYDVEQGDWTG----TGEEVVKFVPEWIQLGVRIVGGCCRVYPTDVLAIRKYVDGLNIK 330
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Zebrafish
Match: zgc:172121 (zgc:172121 [Source:ZFIN;Acc:ZDB-GENE-030131-9545])

HSP 1 Score: 147.902 bits (372), Expect = 1.061e-39
Identity = 89/272 (32.72%), Postives = 144/272 (52.94%), Query Frame = 2 
Query:  146 INH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY--ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPL-WIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            +++ +++   +VIT+ +YQAS         +  EEA+ +M  +V LAK+ + ++  ++  S     L A S+GP+G+ L DGSEY G Y D+ ++ ++++++  QI  L +A  DL+A ETIP   E E ++E++KE+P   AW+S +  D    + G      V+      S  ++  G NC  P L VK  +   +S    D  +V+YPN+GE  D +   W         T +  L L W   GA WIGGCCR+   R   ++E+ Q H
Sbjct:   44 VHYRYLQSGSDVITTATYQASIEGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFISQSPMSDRREPLVAGSVGPYGSFLHDGSEYTGAYEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIPGLKEAEALVEVLKEFPETKAWLSFSCKDNNSISSGRRFSEAVE--MACRSTQLVAVGVNCC-PALLVKPLLESAKSHKRADLSWVVYPNSGEGWDVTTG-W----KTEMRTSFANLSLEWKAQGALWIGGCCRV---RPADITELKQLH 304
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Zebrafish
Match: zgc:172121 (zgc:172121 [Source:ZFIN;Acc:ZDB-GENE-030131-9545])

HSP 1 Score: 147.902 bits (372), Expect = 1.061e-39
Identity = 89/272 (32.72%), Postives = 144/272 (52.94%), Query Frame = 2 
Query:  146 INH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY--ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPL-WIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            +++ +++   +VIT+ +YQAS         +  EEA+ +M  +V LAK+ + ++  ++  S     L A S+GP+G+ L DGSEY G Y D+ ++ ++++++  QI  L +A  DL+A ETIP   E E ++E++KE+P   AW+S +  D    + G      V+      S  ++  G NC  P L VK  +   +S    D  +V+YPN+GE  D +   W         T +  L L W   GA WIGGCCR+   R   ++E+ Q H
Sbjct:   44 VHYRYLQSGSDVITTATYQASIEGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFISQSPMSDRREPLVAGSVGPYGSFLHDGSEYTGAYEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIPGLKEAEALVEVLKEFPETKAWLSFSCKDNNSISSGRRFSEAVE--MACRSTQLVAVGVNCC-PALLVKPLLESAKSHKRADLSWVVYPNSGEGWDVTTG-W----KTEMRTSFANLSLEWKAQGALWIGGCCRV---RPADITELKQLH 304
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Zebrafish
Match: zgc:172121 (zgc:172121 [Source:ZFIN;Acc:ZDB-GENE-030131-9545])

HSP 1 Score: 147.902 bits (372), Expect = 1.061e-39
Identity = 89/272 (32.72%), Postives = 144/272 (52.94%), Query Frame = 2 
Query:  146 INH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY--ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPL-WIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            +++ +++   +VIT+ +YQAS         +  EEA+ +M  +V LAK+ + ++  ++  S     L A S+GP+G+ L DGSEY G Y D+ ++ ++++++  QI  L +A  DL+A ETIP   E E ++E++KE+P   AW+S +  D    + G      V+      S  ++  G NC  P L VK  +   +S    D  +V+YPN+GE  D +   W         T +  L L W   GA WIGGCCR+   R   ++E+ Q H
Sbjct:   44 VHYRYLQSGSDVITTATYQASIEGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFISQSPMSDRREPLVAGSVGPYGSFLHDGSEYTGAYEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIPGLKEAEALVEVLKEFPETKAWLSFSCKDNNSISSGRRFSEAVE--MACRSTQLVAVGVNCC-PALLVKPLLESAKSHKRADLSWVVYPNSGEGWDVTTG-W----KTEMRTSFANLSLEWKAQGALWIGGCCRV---RPADITELKQLH 304
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Xenopus
Match: MGC75760 (uncharacterized protein mgc75760 [Source:NCBI gene;Acc:394486])

HSP 1 Score: 148.288 bits (373), Expect = 1.061e-39
Identity = 83/265 (31.32%), Postives = 141/265 (53.21%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            F+K   EV+++ +YQAS         LSI+E  +L    V LAK+   + ++ ++    IL A SIGP+GA L+DGSEY G Y+   S+ ++++++  Q+  L  A  +L A ETIP Q E E ++E+++E+PN  AW+S +  D   T++G+  +  V   +   S+ ++  G NC  P   V + +         D  +++YPN+G++ D ++    +  G    T  E    W+  GA WIGGCC    + +  +   ++ H
Sbjct:   48 FLKSGAEVLSTATYQASVKGFQEHLGLSIDEVAELFHVGVRLAKEAAAEIKDNRN----ILIAGSIGPYGAFLSDGSEYTGNYLRNMSVEELKDWHRLQMQCLASAGIELFALETIPGQKEAEALLELLREFPNTNAWLSYSCRDMSSTSYGDAFEKAVGIAH--KSKQLVAVGMNCCPPTF-VSSLLTSANKNRGLDIGWIVYPNSGKIWDHNLG---WQGGGTEKTLSEYALEWVNLGAKWIGGCCTTTPSAIATLLHTLRPH 302
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Xenopus
Match: MGC75760 (uncharacterized protein mgc75760 [Source:NCBI gene;Acc:394486])

HSP 1 Score: 139.813 bits (351), Expect = 1.269e-36
Identity = 80/246 (32.52%), Postives = 133/246 (54.07%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGG 895
            F+K   EV+++ +YQAS         LSI+E  +L    V LAK+   + ++ ++    IL A SIGP+GA L+DGSEY G Y+   S+ ++++++  Q+  L  A  +L A ETIP Q E E ++E+++E+PN  AW+S +  D   T++G+  +  V   +   S+ ++  G NC  P   V + +         D  +++YPN+G++ D ++    +  G    T  E    W+  GA WIGG
Sbjct:   48 FLKSGAEVLSTATYQASVKGFQEHLGLSIDEVAELFHVGVRLAKEAAAEIKDNRN----ILIAGSIGPYGAFLSDGSEYTGNYLRNMSVEELKDWHRLQMQCLASAGIELFALETIPGQKEAEALLELLREFPNTNAWLSYSCRDMSSTSYGDAFEKAVGIAH--KSKQLVAVGMNCCPPTF-VSSLLTSANKNRGLDIGWIVYPNSGKIWDHNLG---WQGGGTEKTLSEYALEWVNLGAKWIGG 283
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. UniProt/SwissProt
Match: sp|Q9SDL7|HMT1_ARATH (Homocysteine S-methyltransferase 1 OS=Arabidopsis thaliana OX=3702 GN=HMT-1 PE=1 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 1.789e-41
Identity = 94/275 (34.18%), Postives = 156/275 (56.73%), Query Frame = 2 
Query:  143 KINH*FVKCIKEVITSLSYQAS-PSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLIT-----PILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYP-NVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQ 946
            +++  +++   +++ + SYQA+ P  LS    LSIEE+E L+  SV LA +   ++  K S ++       L AASIG +GA+LADGSEY+G Y +  S+ ++++++ +++  L  A PDLLAFETIP + E +  +E+++E    +PAWI   S DG K   GE+ +  ++  N   S N+   G NC  P   ++N + K  ++L + K  V+YPN+GE+ D    +WL      ++ F      W + GA  IGGCCR   + +  +S  ++
Sbjct:   57 RVHMEYLEAGADIVVTSSYQATIPGFLSR--GLSIEESESLLQKSVELAVEARDRFWEKVSKVSGHSYNRALVAASIGSYGAYLADGSEYSGHYGENVSLDKLKDFHRRRLQVLVEAGPDLLAFETIPNKLEAQACVELLEEEKVQIPAWICFTSVDGEKAPSGESFEECLEPLN--KSNNIYAVGINCAPPQF-IENLIRKF-AKLTK-KAIVVYPNSGEVWDGKAKQWLPSQCFGDDEFEMFATKWRDLGAKLIGGCCRTTPSTINAISRDLK 324
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. UniProt/SwissProt
Match: sp|A4ZGQ8|HMT1_BRAOT (Homocysteine S-methyltransferase 1 OS=Brassica oleracea var. italica OX=36774 GN=HMT1 PE=1 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 4.119e-41
Identity = 96/275 (34.91%), Postives = 153/275 (55.64%), Query Frame = 2 
Query:  143 KINH*FVKCIKEVITSLSYQAS-PSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLIT-----PILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEY-PNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQ 946
            +++  +++   +V+ + SYQA+ P  LS    LS+EE+E L+  SV LA +   ++ +K S  +       L AASIG +GA+LADGSEY+G Y +  S+ ++++++ ++I  L  A PDLLAFETIP + E +  +E+++E    +PAWI   S DG     GE+ +  ++  N   S N+   G NC  P   + N + K  S+L + K  V+YPN+GE+ D    KWL      +  F      W + GA  IGGCCR   + +  +S  ++
Sbjct:   57 RVHMEYLEAGADVVVTSSYQATIPGFLSR--GLSMEESESLLQKSVKLAVEARDRFWDKVSKTSGHSYNRALVAASIGSYGAYLADGSEYSGSYGEDVSLDKLKDFHRRRIQVLVEASPDLLAFETIPNKLEAQACVELLEEENVQIPAWICFTSVDGENAPSGESFQECLETLN--KSNNICAVGINCAPPQF-MDNLIRKF-SKLTQ-KAIVVYPNSGEVWDGKAKKWLPSQCFGDAEFEMFATKWRDLGAKLIGGCCRTTPSTIKAISRDLK 324
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. UniProt/SwissProt
Match: sp|Q9FUN0|HMT1_MAIZE (Homocysteine S-methyltransferase 1 OS=Zea mays OX=4577 GN=HMT-1 PE=2 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 1.080e-40
Identity = 94/272 (34.56%), Postives = 149/272 (54.78%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQAS-PSTLSTCFNLSIEEAEQLMADSVLLA---KDEIRKYENKKS--LITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYP-NVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            +++   +VI S SYQA+ P  ++    +S+ EAE L+  SV LA   +DE  K   +KS  +    L AASIG +GA+LADGSEY+G Y    +  ++++++ +++  L  A PDL+AFE IP Q E + ++E+++E    +P+WI  +S DG     GE+    +   N  +SE V   G NC  P   ++  + + R Q    K   +YPN+GE+ D    +WL    + + +F      W E GA  IGGCCR   + +  VS+I++  
Sbjct:   56 YLEAGADVIISSSYQATIPGFIAR--GMSVAEAEDLLRTSVKLANEARDEFWKSTLRKSKPIYNRALVAASIGSYGAYLADGSEYSGSYGADITAEKLKDFHRRRLQVLASAGPDLIAFEAIPNQMEAQALVELLEEEKVQIPSWICFSSVDGKNLCSGESFADCLKILN--ASEKVAVVGVNCTPPQF-IEGIICEFRKQTK--KAIAVYPNSGEVWDGRAKRWLPVECLGHKSFDALAKRWQEAGASLIGGCCRTTPSTIRAVSKILKGR 320
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. UniProt/SwissProt
Match: sp|Q8LAX0|HMT3_ARATH (Homocysteine S-methyltransferase 3 OS=Arabidopsis thaliana OX=3702 GN=HMT3 PE=1 SV=2)

HSP 1 Score: 141.739 bits (356), Expect = 3.541e-36
Identity = 92/297 (30.98%), Postives = 154/297 (51.85%), Query Frame = 2 
Query:   98 LISPNICVGVLVYYMKINH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENK------------KSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYP-NVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSS-ENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQ 946
            + SP++   V + Y++           +I + SYQA+         LS+ EAE L+  SV +  +    + N+            K+   PIL AAS+G +GA+LADGSEY+G Y D  S   +++++ +++  L ++  DL+AFETIP + E E   ++++E   ++PAW S  S DG+    G++   VV+   +  S +NV+  G NC  P   +   +  +R Q+ R  I V+YPN+GE+ D    KW+   G +   F   +  W + GA   GGCCR   N +  +++++ 
Sbjct:   52 ITSPHLVTKVHLDYLESG-------ANIIITASYQATIQGF-VAKGLSVGEAENLLRRSVEITYEAREIFYNRCTKGSWDFAYAGKASRRPILVAASVGSYGAYLADGSEYSGIYGDSVSKETLKDFHRRRVQILAKSGADLIAFETIPNKLEAEAYADLLEEEDIDIPAWFSFTSKDGVSVPRGDS---VVECAKVADSCKNVVAIGINCTAPRY-IHALIISLR-QMTRKPI-VVYPNSGEVYDGLNKKWIKSEGESEEDFVSYVSKWRDAGASLFGGCCRTTPNTIRAIAKVLS 334
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. UniProt/SwissProt
Match: sp|Q9FUM9|HMT2_MAIZE (Homocysteine S-methyltransferase 2 OS=Zea mays OX=4577 GN=HMT-2 PE=2 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 4.357e-36
Identity = 89/283 (31.45%), Postives = 150/283 (53.00%), Query Frame = 2 
Query:  143 KINH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDE----IRKYENKKSLIT-PILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYP-NVPAWISVNSCDGMKTAHGENL---KGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSHRIKQ 964
            K++  +++    +I + SYQA+     +    S E++E L+  SV +A +     ++++  K + I  P+L AAS+G +GA+LADGSEY+G+Y +  +   +++++ +++  L  A PDL+AFETIP + E E  +E+++E   N+PAW S NS DG+    G++L     + D         V   G NC  P   +   +  IR     DK  ++YPN+GE  D    +W+   G+++  F   +  W + GA  IGGCCR   N +  +   +     KQ
Sbjct:   60 KVHMDYLEAGANIIITASYQATIQGFES-KGFSKEQSENLLTKSVEIALEAREMFLKEHLEKSTPIQHPVLVAASLGSYGAYLADGSEYSGDYGEAGTKEFLKDFHRRRLQVLAEAGPDLIAFETIPNKLEAEAYVELLEECNINIPAWFSFNSKDGVHIVSGDSLIECTTIADK-----CAKVGAVGINCTPPRF-IHGLILSIRKVT--DKPILIYPNSGERYDGEKKEWVESTGVSDGDFVSYVNEWCKDGAVLIGGCCRTTPNTIRAIHRTLNKSPNKQ 333
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. TrEMBL
Match: D1ZZE7 (Homocysteine S-methyltransferase 1-like Protein OS=Tribolium castaneum OX=7070 GN=TcasGA2_TC007465 PE=4 SV=1)

HSP 1 Score: 165.622 bits (418), Expect = 8.671e-43
Identity = 97/277 (35.02%), Postives = 156/277 (56.32%), Query Frame = 2 
Query:  140 MKINH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPI--LCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSC--DGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNR--DKIFVLYPNNGEMLDKSVSKWLFPPGINNN--TFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQ 946
            ++++  ++K   ++I + SYQAS        NLS EE+  L+  SV+LAK  I + + +  L      L A S+GP+GA+L DGSEYNG Y DR S  +  +Y++ +I +L     DLLA ETIP++ E EII++++KEYP++ AW+S  SC  +G  TAHG+N K    +    + + ++  G NC+ P        H +   L    D   ++Y N+GE  D  +       G +NN     E +P+W+  G  +IGGCCR+  N +T++++ ++
Sbjct:   46 IRVHLDYIKAGCDIIETNSYQASVPGFMKYLNLSKEESYNLVKKSVVLAKTAIERAQKEGILQGDAKPLIAGSVGPYGAYLHDGSEYNGYYTDRISREEFVDYHKSRIDALIEGGVDLLAIETIPSKKEAEIIVQLIKEYPDIKAWLSF-SCQTEGACTAHGDNFKDAATSCYKLNPDQILAVGVNCIAP--------HAVEPLLKEITDIPLIVYANSGEKYDPDL-------GWDNNCEKLEEYVPVWLNLGVKYIGGCCRVCDNYITKIADEVR 306
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. TrEMBL
Match: A0A328E7M7 (Hcy-binding domain-containing protein OS=Cuscuta australis OX=267555 GN=DM860_007426 PE=4 SV=1)

HSP 1 Score: 161.77 bits (408), Expect = 3.866e-41
Identity = 98/272 (36.03%), Postives = 149/272 (54.78%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQAS-PSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY-----ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEY-PNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            +++   +V+ + SYQA+ P  L+  F  S+EE E L+  SV LA     K+      N K      L AASIG +GA+LADGSEY G Y    S+ ++++++ +++  L  A PDLLAFETIP + E +  IE+++E    +P+WI  +S DG     GEN K  +D  N   S  V   G NC  P   V   +HK +     +K  V+YPN+GE+ D    +WL     ++  F E+  LW E GA+ IGGCCR   + +  ++ +++ +
Sbjct:   62 YLEAGADVLVTSSYQATLPGFLARGF--SLEEGESLLKGSVHLAIQARDKFWETARRNGKRGYNRALVAASIGSYGAYLADGSEYRGNYGPEVSLEKLKDFHRRRLQVLVEAGPDLLAFETIPNKLEAQACIELLEEENVEIPSWICFSSVDGENAPSGENFKDCLDVTN--KSIRVAAVGVNCAPPQF-VLPLIHKFKQMT--EKAIVVYPNSGEIWDGIQKQWLHSKCFDDERFGEDALLWREAGANLIGGCCRTTPSTIEAIARVLKKN 326
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. TrEMBL
Match: A0A484NK72 (Hcy-binding domain-containing protein OS=Cuscuta campestris OX=132261 GN=CCAM_LOCUS43501 PE=4 SV=1)

HSP 1 Score: 160.999 bits (406), Expect = 5.440e-41
Identity = 97/274 (35.40%), Postives = 150/274 (54.74%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQAS-PSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY-----ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEY-PNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSHRI 958
            +++   +V+ + SYQA+ P  L+  F  S+EE E L+  SV LA     K+      N K      L AASIG +GA+LADGSEY G Y    S+ ++++++ +++  L  A PDLLAFETIP + E +  IE+++E    +P+WI  +S DG     GEN K  +D  N   S  V   G NC  P   V   +H+ +     +K  V+YPN+GE+ D    +WL     ++  F E+  LW E GA+ IGGCCR   + +  ++ +++  ++
Sbjct:   62 YLEAGADVLVTSSYQATLPGFLARGF--SLEEGESLLKGSVHLAIQARDKFWETARRNGKRGYNRALVAASIGSYGAYLADGSEYRGNYGPEVSLEKLKDFHRRRLQVLVEAGPDLLAFETIPNKLEAQACIELLEEENVEIPSWICFSSVDGENAPSGENFKDCLDVIN--KSIRVAAVGINCAPPQF-VLPLIHRFKQMT--EKAIVVYPNSGEIWDGIQKQWLHSRCFDDERFGEDALLWREAGANLIGGCCRTTPSTIEAIAIVLKEQQL 328
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. TrEMBL
Match: A0A1J6KCJ8 (Homocysteine s-methyltransferase 1 OS=Nicotiana attenuata OX=49451 GN=HMT1 PE=4 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 7.684e-41
Identity = 92/270 (34.07%), Postives = 152/270 (56.30%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQAS-PSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKY-----ENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEY-PNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQ 946
            +++   +++ + SYQA+ P  LS    LSIEEAE L+  SV LA +   K+      N +      L AASIG +GA+LADGSEY+G+Y    S+ ++++++  ++  L  A PD+LAFETIP + E +  +E+++E    +P+WI  +S DG     GE+ K  +D  N   S+ V  FG NC  P   ++  + +++      K  ++YPN+GE+ D    +WL     ++  F +  P+W + GA  IGGCCR   + +  +S+ ++
Sbjct:   62 YLEAGADILVTSSYQATIPGFLSR--GLSIEEAESLLEKSVKLAVEARDKFWNVVKRNPRQSYNRALVAASIGSYGAYLADGSEYSGDYGPHVSLDKLKDFHRHRLQVLVDAGPDILAFETIPNKLEAQACVELLEEENVQIPSWICFSSVDGKNAPSGESFKDCLDVIN--RSDKVSAFGINCAPPHF-IQTLIQELKELTA--KAIIVYPNSGEIWDGISKRWLPSKCFDDEKFEQFAPIWRDAGAKLIGGCCRTTPSTIQAISKALK 324
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. TrEMBL
Match: A0A2K1K6B5 (Hcy-binding domain-containing protein OS=Physcomitrella patens subsp. patens OX=3218 GN=PHYPA_011216 PE=4 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 1.433e-40
Identity = 95/295 (32.20%), Postives = 163/295 (55.25%), Query Frame = 2 
Query:  113 ICVGVLVYYMKINH*-FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEI----RKYENK-------KSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIM-KEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIP--LLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            +C+  + + ++  H  +++    VI++ SYQA+     +   LS +EAE L+  SV +A++E     ++Y+NK         L    L AAS+G +GA+LADGSEY+G+Y    ++ ++++++ +++  L  A PDL+A ETIP + E + ++E++ +E   VPAWIS NS DG     G++L   V   +      V   G NC  P  +L++   V K+      +K+ V+YPN+GE  D  + +W+   G+++  F   +  W   GA  IGGCCR   N +  +S+ ++ H
Sbjct:   57 LCLITMPHLIRTVHKEYLQAGASVISTASYQATIQGFQS-RGLSTKEAEDLLQTSVRIAQEERDSFWKEYQNKVRAGTAHAGLYQRALAAASVGSYGAYLADGSEYSGDYGPSMTVDKLKDFHRRRLMVLADAGPDLIALETIPCKLETQALVELLAEENLRVPAWISFNSKDGTNVVSGDSLSDCVALAD--KCTQVRAVGINCTPPRFILDLIQAVRKV-----TNKLIVVYPNSGEYYDPEIKQWVESTGVSDTDFVSYVHEWRNAGAQLIGGCCRTTPNTIEAISKALREH 343
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Cavefish
Match: zgc:172121 (homocysteine S-methyltransferase YbgG-like [Source:NCBI gene;Acc:103040478])

HSP 1 Score: 143.28 bits (360), Expect = 3.727e-38
Identity = 87/264 (32.95%), Postives = 135/264 (51.14%), Query Frame = 2 
Query:  146 INH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPI--LCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRV 931
            +++ F++   +VIT+ +YQA+         L  E+AE+L+   V +AKD    +    +       L A S+GP+GA L DGSEY G Y  + S+ ++++++  Q+  L  AE DL+A ETIP   EVE ++ +++E+PN  AW+S +  D    + G      V+      S  ++  G NC  P L V   +   +SQ   +  +V+YPN+GE  D     W         +F E    W E GA WIGGCCR G   +T +
Sbjct:   44 VHYRFLQSGSDVITTATYQATLEGFFKHLKLKPEQAEELLISGVQIAKDTAALFTTNCTAADRAVPLVAGSVGPYGAFLNDGSEYTGNYQSQMSVEELKDWHRPQVRCLVAAEADLIALETIPCLKEVEALVGLLREFPNTKAWMSFSCKDTQCISGGNKFSQAVELAA--RSTQLVAVGVNCSAPSL-VTPLLESAKSQKAPNMSWVVYPNSGEEWDPK-KGW----KSKRMSFTELSAEWKEQGALWIGGCCRTGPADITEL 299
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Yeast
Match: SAM4 (S-adenosylmethionine-homocysteine methyltransferase; functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio; SAM4 has a paralog, YMR321C, that arose from a single-locus duplication [Source:SGD;Acc:S000006194])

HSP 1 Score: 65.855 bits (159), Expect = 3.523e-12
Identity = 64/270 (23.70%), Postives = 120/270 (44.44%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNL-SIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEP-DLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHG---ENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            F+    E++ + +YQ S  ++S    + ++ E   L+   V  +++ I +    K LI        IGP+GAH+    E+ G+Y           Y++ Q+ +  + +  DL+ FETIP   E++ I+   +   + P +I ++  +      G   E +  V+ +     + N    G NCV    +  + +  +   L  +   + YPN+GE+ D     WL P     N++   +  +I  GA  IGGCCR     +  +S  ++ +
Sbjct:   69 FLNAGAEILMTTTYQTSYKSVSENTPIRTLSEYNNLLNRIVDFSRNCIGE---DKYLI------GCIGPWGAHIC--REFTGDYGAEPENIDFYQYFKPQLENFNKNDKLDLIGFETIPNIHELKAILSWDESILSRPFYIGLSVHEHGVLRDGTTMEEIAQVIKDLGDKINPNFSFLGINCV-SFNQSPDILESLHQAL-PNMALLAYPNSGEVYDTEKKIWL-PNSDKLNSWDTVVKQYISSGARIIGGCCRTSPKDIQEISAAVKKY 324
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Yeast
Match: MHT1 (S-methylmethionine-homocysteine methyltransferase; functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio [Source:SGD;Acc:S000003985])

HSP 1 Score: 62.003 bits (149), Expect = 5.335e-11
Identity = 59/266 (22.18%), Postives = 118/266 (44.36%), Query Frame = 2 
Query:  179 VITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTR-AEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENL-------KGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSH 952
            ++ +++YQA+  ++S   ++    A +   D ++    E    E  + LI       SIGP+ AH++   EY G+Y           +++ Q+ +  +  + DL+ FETIP   E++ I+   ++  + P +I ++  D      G  L       KG+ +  N    +N++  G NCV         + K+  +       ++YPN+GE+ +     W  P     + +   +  +++ GA  IGGCCR     +  ++  +  +
Sbjct:   75 ILMTITYQANFQSISENTSIKTLAAYKRFLDKIVSFTREFIGEE--RYLI------GSIGPWAAHVS--CEYTGDYGPHPENIDYYGFFKPQLENFNQNRDIDLIGFETIPNFHELKAILSWDEDIISKPFYIGLSVDDNSLLRDGTTLEEISVHIKGLGNKIN----KNLLLMGVNCV--SFNQSALILKMLHEHLPGMPLLVYPNSGEIYNPKEKTWHRPTN-KLDDWETTVKKFVDNGARIIGGCCRTSPKDIAEIASAVDKY 323
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Nematostella
Match: EDO40315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7I8])

HSP 1 Score: 138.272 bits (347), Expect = 3.848e-37
Identity = 81/255 (31.76%), Postives = 142/255 (55.69%), Query Frame = 2 
Query:  143 KINH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNG-EMLDKSVSKWL----FPPGINNNTFYEELPLWIEGGADWIG 892
            +++  F+    ++IT+ +YQAS S       ++ +EA +L+   V +A++ + ++ +K S    +  A S+ P+G   +DGSEY+G Y+D  +I  + +++  QI +L     DLLAFETIP Q E E +++++KE+P   AW+S +  DG  T+H E+    +    +  SE +I  G NC  P+  V + + +++ +       V+YPN G E +D+  S+W      PP +   ++ +E   WI+ GA WIG
Sbjct:   23 QVHKSFLTHGSDIITTATYQASISGFCKHLGVTADEARKLIQRGVHIARESVDEFWDKHSNSPQV--AGSVCPYGTCQSDGSEYHGNYVDTMTIKNLMDWHRPQIQALVETGLDLLAFETIPAQKEGEALVQLLKEFPGTKAWLSYSCKDGSHTSHNEDFVSAI-MAAVADSEQIIAVGNNCCSPVY-VTSLIRRLKPKTTLP--IVIYPNKGEEWIDRRYSEWQDTGNVPPVV---SYLDE---WIDSGAQWIG 265
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Nematostella
Match: EDO27759 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T8D2])

HSP 1 Score: 67.781 bits (164), Expect = 1.802e-13
Identity = 44/169 (26.04%), Postives = 76/169 (44.97%), Query Frame = 2 
Query:  431 IRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSE 937
            + +++  QI +L     DLLAFETIP Q E E +++++KE+P   AW+S +  DG  T+H E+    +                               + +  + +++   + + G +          PP +   ++ +E   WI+ GA WIGGCCR     +T +SE
Sbjct:   23 LMDWHRPQIQALVETGLDLLAFETIPAQKEGEALVQLLKEFPGTKAWLSYSCKDGSHTSHNEDFVSAI-------------------------------MAAVADSEQVRYGWQDTGNV----------PPVV---SYLDE---WIDSGAQWIGGCCR---TSLTDISE 141
[Close]
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Medaka
Match: zgc:172121 (homocysteine S-methyltransferase [Source:NCBI gene;Acc:101164391])

HSP 1 Score: 121.709 bits (304), Expect = 2.956e-30
Identity = 81/266 (30.45%), Postives = 144/266 (54.14%), Query Frame = 2 
Query:  149 NH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQ 946
            +H F+    +VIT+ +YQAS     T   +S E A++L+   V LA++ ++ + +     T  L A SIG +GA+L D SEY G + ++ ++ ++++++  Q+  L  A  DLLAFETIP+  E + ++E+++E+P+  AW+S +  D  + + G      V   +   S  ++  G NC  P + V+  +    SQL+ D  +V+YPN+G   D S   W    G ++    E    W++ GA  IGGCC +    +  + ++++
Sbjct:   56 HHRFLLSGADVITTATYQASVQGFVTHLGMSAERAKELLMSGVHLAREVVKNFGSGN---TGPLVAGSIGSYGAYLHDTSEYTGTFAEKMTVDELKDWHRPQVEGLLAAGADLLAFETIPSIKEADAVVELLREFPDSSAWLSFSVKDETRISDGSPFAEAVRVAS--RSAQLLAVGVNCCSPTV-VEPLLDSASSQLSPDMSWVVYPNSGWEYD-SQQGWQ-ARGESSIWIPELSRRWVKQGAALIGGCCCISPAEIAELRKVLK 313
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Medaka
Match: zgc:172121 (homocysteine S-methyltransferase [Source:NCBI gene;Acc:101164391])

HSP 1 Score: 112.079 bits (279), Expect = 7.277e-27
Identity = 78/248 (31.45%), Postives = 134/248 (54.03%), Query Frame = 2 
Query:  149 NH*FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIG 892
            +H F+    +VIT+ +YQAS     T   +S E A++L+   V LA++ ++ + +     T  L A SIG +GA+L D SEY G + ++ ++ ++++++  Q+  L  A  DLLAFETIP+  E + ++E+++E+P+  AW+S +  D  + + G      V   +   S  ++  G NC  P + V+  +    SQL+ D  +V+YPN+G   D S   W    G ++    E    W++ GA  IG
Sbjct:   56 HHRFLLSGADVITTATYQASVQGFVTHLGMSAERAKELLMSGVHLAREVVKNFGSGN---TGPLVAGSIGSYGAYLHDTSEYTGTFAEKMTVDELKDWHRPQVEGLLAAGADLLAFETIPSIKEADAVVELLREFPDSSAWLSFSVKDETRISDGSPFAEAVRVAS--RSAQLLAVGVNCCSPTV-VEPLLDSASSQLSPDMSWVVYPNSGWEYD-SQQGWQ-ARGESSIWIPELSRRWVKQGAALIG 295
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Planmine SMEST
Match: SMESG000036460.1 (SMESG000036460.1)

HSP 1 Score: 548.125 bits (1411), Expect = 0.000e+0
Identity = 264/269 (98.14%), Postives = 265/269 (98.51%), Query Frame = 2 
Query:  158 FVKCIKEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSHRIKQ 964
            F+    EVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSHRIKQ
Sbjct:    5 FLHAGAEVITSLSYQASPSTLSTCFNLSIEEAEQLMADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYIDRTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNVPAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVKNTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPLWIEGGADWIGGCCRMGANRMTRVSEIIQSHRIKQ 273
The following BLAST results are available for this feature:
BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
T13G4.41.496e-1431.41pep chromosome:WBcel235:X:1188453:1190752:-1 gene:... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG106211.186e-2931.21gene:FBgn0032726 transcript:FBtr0081191[more]
CG106211.186e-2931.21gene:FBgn0032726 transcript:FBtr0342926[more]
CG106211.186e-2931.21gene:FBgn0032726 transcript:FBtr0342927[more]
CG106232.285e-2829.18gene:FBgn0032727 transcript:FBtr0344844[more]
CG106232.285e-2829.18gene:FBgn0032727 transcript:FBtr0344845[more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
zgc:1721211.061e-3932.72zgc:172121 [Source:ZFIN;Acc:ZDB-GENE-030131-9545][more]
zgc:1721211.061e-3932.72zgc:172121 [Source:ZFIN;Acc:ZDB-GENE-030131-9545][more]
zgc:1721211.061e-3932.72zgc:172121 [Source:ZFIN;Acc:ZDB-GENE-030131-9545][more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
MGC757601.061e-3931.32uncharacterized protein mgc75760 [Source:NCBI gene... [more]
MGC757601.269e-3632.52uncharacterized protein mgc75760 [Source:NCBI gene... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9SDL7|HMT1_ARATH1.789e-4134.18Homocysteine S-methyltransferase 1 OS=Arabidopsis ... [more]
sp|A4ZGQ8|HMT1_BRAOT4.119e-4134.91Homocysteine S-methyltransferase 1 OS=Brassica ole... [more]
sp|Q9FUN0|HMT1_MAIZE1.080e-4034.56Homocysteine S-methyltransferase 1 OS=Zea mays OX=... [more]
sp|Q8LAX0|HMT3_ARATH3.541e-3630.98Homocysteine S-methyltransferase 3 OS=Arabidopsis ... [more]
sp|Q9FUM9|HMT2_MAIZE4.357e-3631.45Homocysteine S-methyltransferase 2 OS=Zea mays OX=... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
D1ZZE78.671e-4335.02Homocysteine S-methyltransferase 1-like Protein OS... [more]
A0A328E7M73.866e-4136.03Hcy-binding domain-containing protein OS=Cuscuta a... [more]
A0A484NK725.440e-4135.40Hcy-binding domain-containing protein OS=Cuscuta c... [more]
A0A1J6KCJ87.684e-4134.07Homocysteine s-methyltransferase 1 OS=Nicotiana at... [more]
A0A2K1K6B51.433e-4032.20Hcy-binding domain-containing protein OS=Physcomit... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
zgc:1721213.727e-3832.95homocysteine S-methyltransferase YbgG-like [Source... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
SAM43.523e-1223.70S-adenosylmethionine-homocysteine methyltransferas... [more]
MHT15.335e-1122.18S-methylmethionine-homocysteine methyltransferase;... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO403153.848e-3731.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO277591.802e-1326.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
zgc:1721212.956e-3030.45homocysteine S-methyltransferase [Source:NCBI gene... [more]
zgc:1721217.277e-2731.45homocysteine S-methyltransferase [Source:NCBI gene... [more]
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BLAST of Homocysteine S-methyltransferase 1-like Protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000036460.10.000e+098.14SMESG000036460.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030357 ID=SMED30030357|Name=Homocysteine S-methyltransferase 1-like Protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1683bp
TCCGATCTATTTTCTACTTTAAAAAAATTTGATCGAAGTCTCAAAGTTTT
GGATGGTGGATCTGGATTTGAAGCACAAGAATTGTGTGCGAATAAAATTG
ATATCTCCAAATATCTGTGTTGGAGTTCTTGTTTATTATATGAAAATCAA
CCATTAGTTCGTGAAATGTATAAAAGAAGTGATAACTTCTCTAAGTTATC
AAGCAAGCCCCTCAACTTTGTCAACCTGTTTTAATTTATCAATAGAAGAA
GCAGAACAGTTAATGGCCGATTCTGTTTTATTAGCAAAAGATGAAATTAG
AAAATATGAAAATAAAAAATCATTGATCACACCAATTCTTTGTGCAGCAT
CGATTGGACCATTTGGTGCACATTTAGCTGATGGGTCAGAATATAATGGG
GAGTACATAGATCGAACATCGATTTGGCAAATCAGAAATTATTATGAGCA
ACAAATATCGAGTTTAACGAGAGCTGAGCCAGATTTGTTAGCGTTTGAGA
CGATTCCAACACAAGCTGAAGTGGAAATAATAATTGAAATAATGAAGGAA
TACCCTAATGTACCAGCATGGATTTCAGTGAATAGTTGTGACGGGATGAA
AACTGCGCACGGCGAAAATTTGAAAGGAGTAGTAGATAATTTTAATCTAT
TTTCATCTGAAAATGTAATTGGATTTGGGTTCAACTGTGTAATTCCTTTG
TTAGAGGTCAAAAATACAGTTCATAAGATTCGGTCTCAACTAAATCGAGA
TAAAATATTTGTTCTCTATCCTAATAATGGGGAAATGTTGGATAAATCTG
TTTCTAAATGGTTATTTCCTCCGGGAATAAATAATAATACATTCTATGAA
GAATTGCCGTTATGGATTGAAGGCGGAGCTGATTGGATTGGTGGATGTTG
TCGCATGGGTGCTAATAGAATGACTCGAGTTAGTGAAATTATACAATCTC
ATAGAATAAAACAGTAAAGATTTAAAATTTTTGAAACTGAATTCAAACAA
ATTAATTAATAGAACAACTTGACTTAAATTTTGCATGTAAGAAAGACTTT
CCAATATTATCCCACTTATTTAGTTATTATATGAATTTAATTTAGTTTAT
TTTCTCAATTTATTTTATTCTTTAGTAATTTTCTTTTACTTGTAAATTAA
TAATTGTAAAAATAAATGTAATTGCTACTGTTATTATTGATGTGATTTGT
GCAATATAGAATATGATCTAAAATTTATTCTATATAAAATATAAATTGAT
TTCGTTATCTAATTACCAAACACCCCATAATTTTACACCTTACTGCTATG
TAGTGGTGAGTAAAACCACGTTGATACTGTACATAACAGCCGAACATTCC
CCAGGCAGGTGAGCACTGTTTCCAATACTACTCCATGAGAAATCGTCGTT
TACGGGTTCTTGGCAGCTGCTAGAATGTCTTACGTTATTAATTCCTCGTT
GTATTAAGACGCCCCGTGATTATTCCATGCATACGCCGGACCGTACTCCT
CATCGACATTCGGTTGTGATTTCCGCCTTCTGTCATTCACTGGACCCAAT
AGCTCAGTGCTTCTCATCATGTTATGTTCTATGTCCCTAACAATAGAGTT
TAACAGTCAAATTGCCCCAGTTATTGAATTAATTAACAAATTTCGATTTT
GCTTTTATATTAATACCTTGATTTAATATATCT
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protein sequence of SMED30030357-orf-1

>SMED30030357-orf-1 ID=SMED30030357-orf-1|Name=SMED30030357-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=235bp
MADSVLLAKDEIRKYENKKSLITPILCAASIGPFGAHLADGSEYNGEYID
RTSIWQIRNYYEQQISSLTRAEPDLLAFETIPTQAEVEIIIEIMKEYPNV
PAWISVNSCDGMKTAHGENLKGVVDNFNLFSSENVIGFGFNCVIPLLEVK
NTVHKIRSQLNRDKIFVLYPNNGEMLDKSVSKWLFPPGINNNTFYEELPL
WIEGGADWIGGCCRMGANRMTRVSEIIQSHRIKQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0047150betaine-homocysteine S-methyltransferase activity
GO:0008168methyltransferase activity
GO:0016740transferase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0009086methionine biosynthetic process
GO:0032259methylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR036589HCY_dom_sf
IPR003726HCY_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036589Homocysteine-binding domain superfamilyGENE3DG3DSA:3.20.20.330coord: 1..225
e-value: 5.7E-47
score: 162.4
IPR036589Homocysteine-binding domain superfamilySUPERFAMILYSSF82282Homocysteine S-methyltransferasecoord: 24..230
IPR003726Homocysteine-binding domainPFAMPF02574S-methyl_transcoord: 3..225
e-value: 1.3E-34
score: 120.2
IPR003726Homocysteine-binding domainPROSITEPS50970HCYcoord: 1..227
score: 24.081
NoneNo IPR availablePANTHERPTHR46015FAMILY NOT NAMEDcoord: 3..229