Regulator of G protein signaling 12a

Overview


Name	Regulator of G protein signaling 12a
Smed ID	SMED30030346
Length (bp)	2643

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Regulator of G protein signaling 12a (SMED30030346) t-SNE clustered cells

Violin plots show distribution of expression levels for Regulator of G protein signaling 12a (SMED30030346) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Regulator of G protein signaling 12a (SMED30030346) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Regulator of G protein signaling 12a (SMED30030346) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030346

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30030346	h1SMcG0004754	Contig4561	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30030346	h1SMcG0006764	Contig4561	GPL15192	PMID:23079596 Forsthoefel et al., 2012
Smed sexual biotype	SMED30030346	h1SMcG0006764	Contig38706	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30030346	h1SMcG0006764	Contig38706	newmark_ests	PMID:29674431 Fincher et al., 2018
nervous system	SMED30030346	h1SMcG0006764	dd_Smed_v4_5751_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30030346	h1SMcG0006764	dd_Smed_v4_5751_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30030346	h1SMcG0006764	dd_Smed_v4_5751_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30030346	h1SMcG0006764	dd_Smed_v4_5751_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Human
Match: RGS3 (regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999])

HSP 1 Score: 77.411 bits (189), Expect = 1.002e-15
Identity = 40/104 (38.46%), Postives = 59/104 (56.73%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  FQ F+  EFS ENL+FW     F K+  + KM  +A +IF  Y+  ++  + VNL++Y  E  +  L +     FD+A   ++  M+ DSY RFL+S LY
Sbjct:   53 GLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQA-CKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLY 155

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Human
Match: RGS8 (regulator of G protein signaling 8 [Source:HGNC Symbol;Acc:HGNC:16810])

HSP 1 Score: 77.411 bits (189), Expect = 1.343e-15
Identity = 39/104 (37.50%), Postives = 58/104 (55.77%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK L  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK L  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK L  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Human
Match: RGS3 (regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999])

HSP 1 Score: 77.411 bits (189), Expect = 1.696e-15
Identity = 40/104 (38.46%), Postives = 59/104 (56.73%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  FQ F+  EFS ENL+FW     F K+  + KM  +A +IF  Y+  ++  + VNL++Y  E  +  L +     FD+A   ++  M+ DSY RFL+S LY
Sbjct:   77 GLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQA-CKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLY 179

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Celegans
Match: egl-10 (Regulator of G-protein signaling egl-10 [Source:UniProtKB/Swiss-Prot;Acc:P49809])

HSP 1 Score: 73.559 bits (179), Expect = 4.290e-13
Identity = 38/104 (36.54%), Postives = 57/104 (54.81%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G +  Q F+ +E+S ENL+FW EV    K      +      I+N ++D  +    VN++  ++E     L NP    FD A++H+Y  MKNDSY RFL+S +Y
Sbjct:  431 GRETLQKFLDKEYSGENLRFWWEVQKLRKC-SSRMVPVMVTEIYNEFIDTNAATSPVNVDCKVMEVTEDNLKNPNRWSFDEAADHIYCLMKNDSYQRFLRSEIY 533

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Celegans
Match: egl-10 (Regulator of G-protein signaling egl-10 [Source:UniProtKB/Swiss-Prot;Acc:P49809])

HSP 1 Score: 73.1738 bits (178), Expect = 4.445e-13
Identity = 38/104 (36.54%), Postives = 57/104 (54.81%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G +  Q F+ +E+S ENL+FW EV    K      +      I+N ++D  +    VN++  ++E     L NP    FD A++H+Y  MKNDSY RFL+S +Y
Sbjct:  431 GRETLQKFLDKEYSGENLRFWWEVQKLRKC-SSRMVPVMVTEIYNEFIDTNAATSPVNVDCKVMEVTEDNLKNPNRWSFDEAADHIYCLMKNDSYQRFLRSEIY 533

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Celegans
Match: egl-10 (Regulator of G-protein signaling egl-10 [Source:UniProtKB/Swiss-Prot;Acc:P49809])

HSP 1 Score: 73.1738 bits (178), Expect = 4.858e-13
Identity = 38/104 (36.54%), Postives = 57/104 (54.81%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G +  Q F+ +E+S ENL+FW EV    K      +      I+N ++D  +    VN++  ++E     L NP    FD A++H+Y  MKNDSY RFL+S +Y
Sbjct:  431 GRETLQKFLDKEYSGENLRFWWEVQKLRKC-SSRMVPVMVTEIYNEFIDTNAATSPVNVDCKVMEVTEDNLKNPNRWSFDEAADHIYCLMKNDSYQRFLRSEIY 533

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Celegans
Match: rgs-2 (Regulator of G-protein signaling rgs-2 [Source:UniProtKB/Swiss-Prot;Acc:P49808])

HSP 1 Score: 66.2402 bits (160), Expect = 2.021e-12
Identity = 37/110 (33.64%), Postives = 59/110 (53.64%), Query Frame = 2

Query: 1037 CGLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEA---YRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDS 1357
             G KYF  F+  E+S EN+ FWQ      +  + EK++++A   Y  F + + PK     V+L++ + E     +  P  + FD A N +Y  M+ DSY RFL S++Y +
Sbjct:   45 AGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDFISILSPKE----VSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKT 150

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Celegans
Match: rgs-2 (Regulator of G-protein signaling rgs-2 [Source:UniProtKB/Swiss-Prot;Acc:P49808])

HSP 1 Score: 66.2402 bits (160), Expect = 2.988e-12
Identity = 37/110 (33.64%), Postives = 59/110 (53.64%), Query Frame = 2

Query: 1037 CGLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEA---YRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDS 1357
             G KYF  F+  E+S EN+ FWQ      +  + EK++++A   Y  F + + PK     V+L++ + E     +  P  + FD A N +Y  M+ DSY RFL S++Y +
Sbjct:   64 AGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDFISILSPKE----VSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKT 169

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Fly
Match: RSG7 (gene:FBgn0024941 transcript:FBtr0074350)

HSP 1 Score: 76.2554 bits (186), Expect = 6.226e-14
Identity = 39/112 (34.82%), Postives = 70/112 (62.50%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMN---MFDIASNHVYQTMKNDSYTRFLKSSLYDSWRN 1366
            G + F  F+ +E+S ENLKFW+ V    K L + ++K+   +I+  ++ P++    VN+++  +E AR+ + +P       FD+A++HVY  MK+DSY+R+L+S +Y  + N
Sbjct:  521 GREQFTKFLEKEYSGENLKFWESVQEM-KALPQSEIKEAIQKIWQEFLAPEAP-CPVNVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKDYLN 630

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Fly
Match: RSG7 (gene:FBgn0024941 transcript:FBtr0307538)

HSP 1 Score: 76.2554 bits (186), Expect = 6.226e-14
Identity = 39/112 (34.82%), Postives = 70/112 (62.50%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMN---MFDIASNHVYQTMKNDSYTRFLKSSLYDSWRN 1366
            G + F  F+ +E+S ENLKFW+ V    K L + ++K+   +I+  ++ P++    VN+++  +E AR+ + +P       FD+A++HVY  MK+DSY+R+L+S +Y  + N
Sbjct:  521 GREQFTKFLEKEYSGENLKFWESVQEM-KALPQSEIKEAIQKIWQEFLAPEAP-CPVNVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKDYLN 630

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Fly
Match: CG42450 (gene:FBgn0259927 transcript:FBtr0310343)

HSP 1 Score: 62.3882 bits (150), Expect = 2.042e-9
Identity = 34/105 (32.38%), Postives = 56/105 (53.33%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQ-TMKNDSYTRFLKSSLY 1351
            GL+ F  F+ +E+S EN++FW  VN   +    +  +K    I+  ++ P +  + +N++   +E   K L NP    FD AS H+Y   +K D Y RF++S  Y
Sbjct:  511 GLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVARK-VNEIYEEFLKPGAPCE-INIDGKTMESVLKGLKNPSRFTFDSASEHIYMLLLKKDCYPRFIRSEHY 613

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Fly
Match: CG42450 (gene:FBgn0259927 transcript:FBtr0300218)

HSP 1 Score: 62.3882 bits (150), Expect = 2.063e-9
Identity = 34/105 (32.38%), Postives = 56/105 (53.33%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQ-TMKNDSYTRFLKSSLY 1351
            GL+ F  F+ +E+S EN++FW  VN   +    +  +K    I+  ++ P +  + +N++   +E   K L NP    FD AS H+Y   +K D Y RF++S  Y
Sbjct:  511 GLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVARK-VNEIYEEFLKPGAPCE-INIDGKTMESVLKGLKNPSRFTFDSASEHIYMLLLKKDCYPRFIRSEHY 613

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Fly
Match: loco (gene:FBgn0020278 transcript:FBtr0084273)

HSP 1 Score: 61.2326 bits (147), Expect = 4.334e-9
Identity = 33/106 (31.13%), Postives = 55/106 (51.89%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDS 1357
            G++ F  F+ +EFS+EN+ FW     +  +  E     +A  IF  ++   S D  VN+++       +KL +   ++F  A   ++  MK DSY RF++S LY S
Sbjct:  837 GMQTFSEFLKKEFSAENIYFWTACERYRLLESEADRVAQAREIFAKHLANNSSD-PVNVDSQARSLTEEKLADAAPDIFAPAQKQIFSLMKFDSYQRFIRSDLYKS 941

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Zebrafish
Match: rgs3b (regulator of G protein signaling 3b [Source:ZFIN;Acc:ZDB-GENE-060531-24])

HSP 1 Score: 80.1073 bits (196), Expect = 1.497e-16
Identity = 43/112 (38.39%), Postives = 63/112 (56.25%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEIR 1375
            GL  F+ F+  EFS ENL FW     F KI    KM   A +IF  Y+  +S  + VNL++Y  E  ++ + N C + FD+A + ++  M+ DSY RFL+S +Y    N+ R
Sbjct:   79 GLAVFRSFLQTEFSEENLDFWLACEEFKKIKSLSKMTSRAKKIFTEYISIQSCKE-VNLDSYTREHIKENMENICADCFDLAQSRIFGLMERDSYPRFLRSDIYMELTNQKR 189

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Zebrafish
Match: rgs3b (regulator of G protein signaling 3b [Source:ZFIN;Acc:ZDB-GENE-060531-24])

HSP 1 Score: 81.6481 bits (200), Expect = 2.746e-15
Identity = 43/112 (38.39%), Postives = 63/112 (56.25%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEIR 1375
            GL  F+ F+  EFS ENL FW     F KI    KM   A +IF  Y+  +S  + VNL++Y  E  ++ + N C + FD+A + ++  M+ DSY RFL+S +Y    N+ R
Sbjct:  748 GLAVFRSFLQTEFSEENLDFWLACEEFKKIKSLSKMTSRAKKIFTEYISIQSCKE-VNLDSYTREHIKENMENICADCFDLAQSRIFGLMERDSYPRFLRSDIYMELTNQKR 858

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Zebrafish
Match: RGS13 (si:ch211-117l17.5 [Source:ZFIN;Acc:ZDB-GENE-110914-230])

HSP 1 Score: 74.7146 bits (182), Expect = 3.021e-15
Identity = 37/106 (34.91%), Postives = 60/106 (56.60%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDS 1357
            GL  F+ F+  EFS EN++FW     +  I    KM  +A +IF  +++ +S  + +N++    E+ ++K+ +P    FD A   VY  M+ DSY RFL+S +Y S
Sbjct:   38 GLATFRTFLKSEFSDENIEFWLTCEDYKTITSSHKMSSKARKIFEQFVEAESPKE-INIDYQTREEIKRKMKSPTAQCFDEAQKIVYGLMERDSYPRFLRSEMYKS 142

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Zebrafish
Match: BX936311.1 (si:ch211-117l17.5 [Source:NCBI gene;Acc:792554])

HSP 1 Score: 74.3294 bits (181), Expect = 6.759e-15
Identity = 37/106 (34.91%), Postives = 60/106 (56.60%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDS 1357
            GL  F+ F+  EFS EN++FW     +  I    KM  +A +IF  +++ +S  + +N++    E+ ++K+ +P    FD A   VY  M+ DSY RFL+S +Y S
Sbjct:   53 GLATFRTFLKSEFSDENIEFWLTCEDYKTITSSHKMSSKARKIFEQFVEAESPKE-INIDYQTREEIKRKMKSPTAQCFDEAQKIVYGLMERDSYPRFLRSEMYKS 157

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Zebrafish
Match: RGS13 (si:ch211-117l17.5 [Source:ZFIN;Acc:ZDB-GENE-110914-230])

HSP 1 Score: 74.3294 bits (181), Expect = 9.406e-15
Identity = 37/106 (34.91%), Postives = 60/106 (56.60%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDS 1357
            GL  F+ F+  EFS EN++FW     +  I    KM  +A +IF  +++ +S  + +N++    E+ ++K+ +P    FD A   VY  M+ DSY RFL+S +Y S
Sbjct:   67 GLATFRTFLKSEFSDENIEFWLTCEDYKTITSSHKMSSKARKIFEQFVEAESPKE-INIDYQTREEIKRKMKSPTAQCFDEAQKIVYGLMERDSYPRFLRSEMYKS 171

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Xenopus
Match: cipc (CLOCK-interacting pacemaker [Source:Xenbase;Acc:XB-GENE-5806252])

HSP 1 Score: 70.8626 bits (172), Expect = 4.681e-13
Identity = 35/105 (33.33%), Postives = 60/105 (57.14%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYD 1354
            G   F+ F+  EFS ENL+FW     + K     K+  +A+ IF  ++D ++  + VNL+    E  ++ L +P ++ FD+A   ++  M+ DSY RFL+S +Y+
Sbjct:  102 GRTMFRAFLQTEFSEENLEFWVACEEYRKTRSLNKLPAKAHHIFQEFIDVQAPRE-VNLDYPTRELTKRNLLHPTLSCFDLAQLRIHSLMERDSYPRFLRSKMYN 205

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Xenopus
Match: cipc (CLOCK-interacting pacemaker [Source:Xenbase;Acc:XB-GENE-5806252])

HSP 1 Score: 69.707 bits (169), Expect = 4.729e-13
Identity = 35/104 (33.65%), Postives = 59/104 (56.73%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G   F+ F+  EFS ENL+FW     + K     K+  +A+ IF  ++D ++  + VNL+    E  ++ L +P ++ FD+A   ++  M+ DSY RFL+S +Y
Sbjct:   62 GRTMFRAFLQTEFSEENLEFWVACEEYRKTRSLNKLPAKAHHIFQEFIDVQAPRE-VNLDYPTRELTKRNLLHPTLSCFDLAQLRIHSLMERDSYPRFLRSKMY 164

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Xenopus
Match: rgs18 (regulator of G-protein signaling 18 [Source:NCBI gene;Acc:493454])

HSP 1 Score: 70.4774 bits (171), Expect = 7.831e-13
Identity = 40/106 (37.74%), Postives = 59/106 (55.66%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTY--MDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G++ F+ F+  EFS ENL+FW E   + K    ++M  +A  ++  Y  MD   E   VNL+    E  +K +  P +  FD+A   +Y  M+ DSY RFLKSS+Y
Sbjct:   94 GIEAFKKFLKMEFSDENLEFWLECEEYKKCQTNKQMDDKAKSLYEKYIQMDSPRE---VNLDFATKEMTKKSIEQPELTSFDLAQTKIYSLMEKDSYPRFLKSSVY 196

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Xenopus
Match: nhlrc3 (NHL repeat containing 3 [Source:Xenbase;Acc:XB-GENE-988782])

HSP 1 Score: 70.0922 bits (170), Expect = 1.375e-12
Identity = 34/105 (32.38%), Postives = 59/105 (56.19%), Query Frame = 2

Query: 1037 CGLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            CGL  F+ F+  E+S EN+ FW     + K+   EK+ ++A +I+  ++  ++  + VNL++   E+    +  P  + FD A + ++  M+ DSY RFLKS  Y
Sbjct:  110 CGLAAFRAFLQSEYSEENIDFWLACENYKKVKTPEKLLEKAQKIYEDFISVEA-TREVNLDSATREETSNNIIQPTHSTFDEAQHRIFILMEKDSYRRFLKSKFY 213

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Xenopus
Match: ENSXETT00000026168.1 (regulator of G-protein signaling 14 [Source:NCBI gene;Acc:100490892])

HSP 1 Score: 70.4774 bits (171), Expect = 8.208e-12
Identity = 39/107 (36.45%), Postives = 61/107 (57.01%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKIL--DEEKMKKEAYRIFNTYMDPKSEDQT-VNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G++YF  F+ +E+S+EN+ FW+    F  I   D EK+ +E++RI+N Y+   S     ++ +  I ED    L  P  ++F      ++  MK DSY RF+KSSLY
Sbjct:   61 GVEYFTEFLKKEYSAENIYFWKACEKFQSISNDDSEKLLQESHRIYNEYLSSSSLCPVNIDQQALITEDM---LETPSPDLFKAQQLQIFNLMKFDSYARFVKSSLY 164

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BLAST of Regulator of G protein signaling 12a vs. Ensembl Mouse
Match: Rgs3 (regulator of G-protein signaling 3 [Source:MGI Symbol;Acc:MGI:1354734])

HSP 1 Score: 77.411 bits (189), Expect = 2.411e-16
Identity = 39/104 (37.50%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL+ FQ F+  EFS ENL+FW     F K+  + KM  +A +IF  ++  ++  + VNL++Y  E  ++ L +     FD+A   ++  M+ DSY RFL+S LY
Sbjct:   11 GLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKKIFAEFIAIQA-CKEVNLDSYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDLY 113

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Mouse
Match: Rgs8 (regulator of G-protein signaling 8 [Source:MGI Symbol;Acc:MGI:108408])

HSP 1 Score: 76.2554 bits (186), Expect = 2.145e-15
Identity = 38/104 (36.54%), Postives = 58/104 (55.77%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK +  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK +  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK +  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Mouse
Match: Rgs3 (regulator of G-protein signaling 3 [Source:MGI Symbol;Acc:MGI:1354734])

HSP 1 Score: 76.6406 bits (187), Expect = 2.169e-15
Identity = 39/104 (37.50%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL+ FQ F+  EFS ENL+FW     F K+  + KM  +A +IF  ++  ++  + VNL++Y  E  ++ L +     FD+A   ++  M+ DSY RFL+S LY
Sbjct:   77 GLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKKIFAEFIAIQA-CKEVNLDSYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDLY 179

[Close]

BLAST of Regulator of G protein signaling 12a vs. UniProt/SwissProt
Match: sp|P57771|RGS8_HUMAN (Regulator of G-protein signaling 8 OS=Homo sapiens OX=9606 GN=RGS8 PE=1 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 6.449e-15
Identity = 39/104 (37.50%), Postives = 58/104 (55.77%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK L  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

BLAST of Regulator of G protein signaling 12a vs. UniProt/SwissProt
Match: sp|P49804|RGS8_RAT (Regulator of G-protein signaling 8 OS=Rattus norvegicus OX=10116 GN=Rgs8 PE=1 SV=2)

HSP 1 Score: 76.2554 bits (186), Expect = 1.458e-14
Identity = 38/104 (36.54%), Postives = 58/104 (55.77%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK +  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

BLAST of Regulator of G protein signaling 12a vs. UniProt/SwissProt
Match: sp|Q8BXT1|RGS8_MOUSE (Regulator of G-protein signaling 8 OS=Mus musculus OX=10090 GN=Rgs8 PE=1 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 1.501e-14
Identity = 38/104 (36.54%), Postives = 58/104 (55.77%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK +  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   66 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 168

[Close]

BLAST of Regulator of G protein signaling 12a vs. UniProt/SwissProt
Match: sp|Q95K68|RGS8_MACFA (Regulator of G-protein signaling 8 OS=Macaca fascicularis OX=9541 GN=RGS8 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.081e-14
Identity = 38/104 (36.54%), Postives = 58/104 (55.77%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  F+ F+  EFS ENL+FW     F K     K+  +A+RIF  ++D ++  + VN++    E  RK +  P +  FD A   V+  M+ DSY RFL+S +Y
Sbjct:   82 GVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE-VNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMY 184

[Close]

BLAST of Regulator of G protein signaling 12a vs. UniProt/SwissProt
Match: sp|P49796|RGS3_HUMAN (Regulator of G-protein signaling 3 OS=Homo sapiens OX=9606 GN=RGS3 PE=1 SV=2)

HSP 1 Score: 78.9518 bits (193), Expect = 1.498e-13
Identity = 40/104 (38.46%), Postives = 59/104 (56.73%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  FQ F+  EFS ENL+FW     F K+  + KM  +A +IF  Y+  ++  + VNL++Y  E  +  L +     FD+A   ++  M+ DSY RFL+S LY
Sbjct: 1083 GLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKE-VNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLY 1185

[Close]

BLAST of Regulator of G protein signaling 12a vs. TrEMBL
Match: A0A2P6MVJ3 (Regulator of G-protein signaling 21 OS=Planoprotostelium fungivorum OX=1890364 GN=PROFUN_09138 PE=4 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 3.342e-14
Identity = 42/111 (37.84%), Postives = 69/111 (62.16%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEI 1372
            G+ YF+ F+  EFS ENL F+  V  +  I DE   K +A  IFN+Y+ P +  Q +N++  I+ED RKK+ +P + +FD   + ++  M++DS+ RFLKS ++   +N +
Sbjct:  206 GVNYFRTFLKTEFSVENLNFYLAVERYRAITDESTRKTKAEEIFNSYIKPNA-PQELNIDQSILEDIRKKMDHPTVQLFDPVQSAIHVLMRDDSFPRFLKSGIFHRLQNRV 315

[Close]

BLAST of Regulator of G protein signaling 12a vs. TrEMBL
Match: A0A2P6N4X4 (Uncharacterized protein OS=Planoprotostelium fungivorum OX=1890364 GN=PROFUN_13252 PE=4 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 4.052e-14
Identity = 42/111 (37.84%), Postives = 69/111 (62.16%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEI 1372
            G+ YF+ F+  EFS ENL F+  V  +  I DE   K +A  IFN+Y+ P +  Q +N++  I+ED RKK+ +P + +FD   + ++  M++DS+ RFLKS ++   +N +
Sbjct:  730 GVNYFRTFLKTEFSVENLNFYLAVERYRAITDESTRKTKAEEIFNSYIKPNAP-QELNIDQSILEDIRKKMDHPTVQLFDPVQSAIHVLMRDDSFPRFLKSGIFHRLQNRV 839

[Close]

BLAST of Regulator of G protein signaling 12a vs. TrEMBL
Match: A0A3M7QPA7 (Regulator of G-signaling 14-like isoform X1 (Fragment) OS=Brachionus plicatilis OX=10195 GN=BpHYR1_041925 PE=4 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 5.207e-14
Identity = 43/104 (41.35%), Postives = 66/104 (63.46%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F  F+ +E+S EN+ FW     F KI D ++MKKEA  I+ TY+D  S+ Q +N++N    + ++ + NP   MF++A + ++  MK DSY+RFLKS +Y
Sbjct:  363 GLNIFTDFLKKEYSEENIDFWVRCEKFKKISDLDEMKKEAEDIWQTYLDTSSQCQ-INVDNKTRSNCKEGMQNPHCKMFELAQSQIFTLMKYDSYSRFLKSQMY 465

[Close]

BLAST of Regulator of G protein signaling 12a vs. TrEMBL
Match: A0A2I0T5P5 (RGS domain-containing protein OS=Limosa lapponica baueri OX=1758121 GN=llap_20580 PE=4 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 5.275e-14
Identity = 43/104 (41.35%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     F KI  + KM  +A +IF  Y+  +S  + VNL++Y  E  ++ L N   + FD+A   +Y  M+ DSY RFL+S LY
Sbjct:    4 GLAAFRAFLRTEFSEENLEFWLACEEFKKIKSQSKMVSKAKKIFAEYIAIQS-CKEVNLDSYTREHTKENLQNITRSCFDLAQKRIYGLMEKDSYPRFLRSDLY 106

[Close]

BLAST of Regulator of G protein signaling 12a vs. TrEMBL
Match: A0A091KUV7 (Regulator of G-protein signaling 3 (Fragment) OS=Chlamydotis macqueenii OX=187382 GN=N324_06703 PE=4 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 7.130e-14
Identity = 43/104 (41.35%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     F KI  + KM  +A +IF  Y+  +S  + VNL++Y  E  ++ L N   + FD+A   +Y  M+ DSY RFL+S LY
Sbjct:   24 GLAAFRAFLRTEFSEENLEFWLACEEFKKIKSQSKMVSKAKKIFTEYIAIQS-CKEVNLDSYTREHTKENLQNITRSCFDLAQKRIYGLMEKDSYPRFLRSDLY 126

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Cavefish
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 79.337 bits (194), Expect = 1.299e-16
Identity = 42/104 (40.38%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  E  ++ L N   + FD+A   +Y  M+ DSY RFL+S LY
Sbjct:   58 GLAAFRAFLRTEFSEENLEFWLACEDYKKIKSQSKMASKAKKIFAEYIAIQS-CKEVNLDSYTREHTKENLQNITRSCFDLAQRRIYGLMEKDSYPRFLRSELY 160

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Cavefish
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 78.9518 bits (193), Expect = 2.348e-16
Identity = 42/104 (40.38%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  E  ++ L N   + FD+A   +Y  M+ DSY RFL+S LY
Sbjct:   72 GLAAFRAFLRTEFSEENLEFWLACEDYKKIKSQSKMASKAKKIFAEYIAIQS-CKEVNLDSYTREHTKENLQNITRSCFDLAQRRIYGLMEKDSYPRFLRSELY 174

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Cavefish
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 81.2629 bits (199), Expect = 1.778e-15
Identity = 42/104 (40.38%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  E  ++ L N   + FD+A   +Y  M+ DSY RFL+S LY
Sbjct:  391 GLAAFRAFLRTEFSEENLEFWLACEDYKKIKSQSKMASKAKKIFAEYIAIQSCKE-VNLDSYTREHTKENLQNITRSCFDLAQRRIYGLMEKDSYPRFLRSELY 493

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Cavefish
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 81.2629 bits (199), Expect = 2.007e-15
Identity = 42/104 (40.38%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  E  ++ L N   + FD+A   +Y  M+ DSY RFL+S LY
Sbjct:  438 GLAAFRAFLRTEFSEENLEFWLACEDYKKIKSQSKMASKAKKIFAEYIAIQSCKE-VNLDSYTREHTKENLQNITRSCFDLAQRRIYGLMEKDSYPRFLRSELY 540

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Cavefish
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 81.2629 bits (199), Expect = 2.017e-15
Identity = 42/104 (40.38%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  E  ++ L N   + FD+A   +Y  M+ DSY RFL+S LY
Sbjct:  472 GLAAFRAFLRTEFSEENLEFWLACEDYKKIKSQSKMASKAKKIFAEYIAIQSCKE-VNLDSYTREHTKENLQNITRSCFDLAQRRIYGLMEKDSYPRFLRSELY 574

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006812.1 (pep scaffold:Pmarinus_7.0:GL476397:246833:248901:1 gene:ENSPMAG00000006145.1 transcript:ENSPMAT00000006812.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 6.840e-16
Identity = 38/104 (36.54%), Postives = 57/104 (54.81%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  FQ F+  EFS EN+ FW     + K     K+  +A +IF+ Y+  +S ++ VNL++   E     L  P  + FD+A   ++  M+ DSY RFL+S LY
Sbjct:   48 GLAAFQAFLRTEFSEENINFWLACEDYKKTKSAAKLTSKARKIFSEYIAIQSPNE-VNLDSCTRELTAANLAKPTADAFDVAQKRIFGLMEKDSYPRFLRSQLY 150

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Sea Lamprey
Match: RGS7 (regulator of G protein signaling 7 [Source:HGNC Symbol;Acc:HGNC:10003])

HSP 1 Score: 72.0182 bits (175), Expect = 2.041e-13
Identity = 37/105 (35.24%), Postives = 60/105 (57.14%), Query Frame = 2

Query: 1037 CGLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
             G   F  F+  EFSSENL+FWQ V    +    E + +   RI+  ++ P + + ++NL+++  E   + +  PC   F+ A  H+Y+ MK+DSY RFL+S +Y
Sbjct:  346 AGQDRFLRFLQSEFSSENLEFWQAVQELKRRPLRE-VPEHVQRIWEEFLAPGALN-SINLDSHSFERTAQNICEPCRYTFEDAQEHIYKLMKSDSYGRFLRSPIY 448

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010442.1 (pep scaffold:Pmarinus_7.0:GL482357:13581:16779:-1 gene:ENSPMAG00000009454.1 transcript:ENSPMAT00000010442.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.0106 bits (162), Expect = 2.816e-13
Identity = 37/104 (35.58%), Postives = 56/104 (53.85%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G + F  F+  EFSSENL+FW  V    + L   K+   A  I+  +++P + + T+NL+++  E     +  P    F  A  H+Y  MK DSY RFL+S+ Y
Sbjct:   26 GQEQFLRFLQSEFSSENLQFWVAVQELKR-LPLRKVADRAREIWQEFLEPGAPN-TINLDSHSFERTAHNVREPGRFAFQDAQEHIYMLMKTDSYARFLRSNNY 127

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010441.1 (pep scaffold:Pmarinus_7.0:GL482357:13581:16779:-1 gene:ENSPMAG00000009454.1 transcript:ENSPMAT00000010441.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.2402 bits (160), Expect = 1.021e-12
Identity = 38/104 (36.54%), Postives = 56/104 (53.85%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G + F  F+  EFSSENL+FW  V    K L   K+   A  I+  +++P + + T+NL+++  E     +  P    F  A  H+Y  MK DSY RFL+S+ Y
Sbjct:   26 GQEQFLRFLQSEFSSENLQFWVAVQEL-KRLPLRKVADRAREIWQEFLEPGAPN-TINLDSHSFERTAHNVREPGRFAFQDAQEHIYMLMKTDSYARFLRSNNY 127

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010444.1 (pep scaffold:Pmarinus_7.0:GL482357:14059:16996:-1 gene:ENSPMAG00000009454.1 transcript:ENSPMAT00000010444.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.855 bits (159), Expect = 1.423e-12
Identity = 38/105 (36.19%), Postives = 56/105 (53.33%), Query Frame = 2

Query: 1037 CGLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
             G + F  F+  EFSSENL+FW  V    K L   K+   A  I+  +++P + + T+NL+++  E     +  P    F  A  H+Y  MK DSY RFL+S+ Y
Sbjct:   45 VGQEQFLRFLQSEFSSENLQFWVAVQEL-KRLPLRKVADRAREIWQEFLEPGAPN-TINLDSHSFERTAHNVREPGRFAFQDAQEHIYMLMKTDSYARFLRSNNY 147

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Nematostella
Match: EDO43126 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZM8])

HSP 1 Score: 81.6481 bits (200), Expect = 8.298e-16
Identity = 42/104 (40.38%), Postives = 60/104 (57.69%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+ +EFS EN+ FW     F  I D +K+K  A  IF T++ P +    VN+++  ++ A + L NP  +M+ +    VY  MK DSY RFLKS LY
Sbjct:  667 GLHCFEEFLKKEFSEENIVFWIACEEFRSISDPKKLKSAASTIFETHLSPNAL-MPVNIDSSAVKVAEEHLLNPTNHMYRVPQQQVYTLMKFDSYPRFLKSDLY 769

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Nematostella
Match: EDO34351 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPN2])

HSP 1 Score: 71.633 bits (174), Expect = 3.946e-13
Identity = 39/104 (37.50%), Postives = 59/104 (56.73%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G KYF  F+ +EFS+ENL FW       K    +++ ++A  I+  Y+   S    +N++    E+    L  P   MFD A +H++Q MK+DSY+RFL+S LY
Sbjct:  286 GRKYFTRFLEKEFSAENLAFWLACERL-KATPIKQVPEKAQEIYTEYLSEHS-TSPINVDCKTHEEVEMNLEKPGRYMFDAAQDHIFQLMKSDSYSRFLRSELY 387

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Nematostella
Match: EDO32804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU35])

HSP 1 Score: 62.7734 bits (151), Expect = 1.852e-11
Identity = 33/104 (31.73%), Postives = 55/104 (52.88%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G+  FQ F+  ++  ENL FW  V  + ++ D E  +  A  I+  Y+   S  + ++L+  I     K +++P  N FD A +H+Y  M +D + RF+KS  Y
Sbjct:   55 GVNQFQEFLRSQYGEENLCFWLAVEDYRRLEDRESRRDMARMIYEDYVSTLSPTE-ISLDAKIRATVDKSMSDPDQNTFDPAQDHIYTLMYHDCFPRFIKSKHY 157

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Nematostella
Match: EDO37370 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFZ6])

HSP 1 Score: 58.151 bits (139), Expect = 7.344e-10
Identity = 34/110 (30.91%), Postives = 55/110 (50.00%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNE 1369
            G++ F  F+  E+S ENL FW  V    K  +   +K  A  I+N Y+  +S  + V++++   +    +++ P    F  A  HVY  M  D Y RFL SS + + + E
Sbjct:   46 GIRVFHEFLKSEYSEENLLFWLAVERLKKETEPASVKNLAQTIYNDYVSTESPKE-VSIDHKTRQVIDDEISQPTKETFSKAQQHVYYVMYQDCYPRFLSSSTFKTLQQE 154

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Medaka
Match: rgs14a (regulator of G protein signaling 14 [Source:NCBI gene;Acc:101156505])

HSP 1 Score: 80.4925 bits (197), Expect = 3.044e-15
Identity = 45/108 (41.67%), Postives = 65/108 (60.19%), Query Frame = 2

Query: 1037 CGLKYFQIFVSREFSSENLKFWQEVNTFSKILDE--EKMKKEAYRIFNTYMDPKSEDQTVNLENYI-IEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            CG++YF  F+  E S+EN+ FWQE   F KI     EK+K EA  I+ TY+   S   +VN+++   IE+  K L  P  +MF+ A   +++ MK DSY RF++S LY
Sbjct:   67 CGVRYFTGFLKSEVSAENILFWQECEKFRKIPATSLEKLKVEARSIYKTYLS-DSAPYSVNIDDTAKIEE--KDLEQPTPDMFNKAQTQIFKLMKMDSYRRFVRSPLY 171

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Medaka
Match: rgs14a (regulator of G protein signaling 14 [Source:NCBI gene;Acc:101156505])

HSP 1 Score: 80.1073 bits (196), Expect = 4.249e-15
Identity = 45/108 (41.67%), Postives = 65/108 (60.19%), Query Frame = 2

Query: 1037 CGLKYFQIFVSREFSSENLKFWQEVNTFSKILDE--EKMKKEAYRIFNTYMDPKSEDQTVNLENYI-IEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            CG++YF  F+  E S+EN+ FWQE   F KI     EK+K EA  I+ TY+   S   +VN+++   IE+  K L  P  +MF+ A   +++ MK DSY RF++S LY
Sbjct:   98 CGVRYFTGFLKSEVSAENILFWQECEKFRKIPATSLEKLKVEARSIYKTYLS-DSAPYSVNIDDTAKIEE--KDLEQPTPDMFNKAQTQIFKLMKMDSYRRFVRSPLY 202

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Medaka
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 77.411 bits (189), Expect = 3.085e-14
Identity = 40/104 (38.46%), Postives = 60/104 (57.69%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  +  +  L N   + F++A   +Y  M+ DSY RFL+S LY
Sbjct:  479 GLAAFRAFLRTEFSEENLEFWLACEEYKKIKSQSKMASKAKKIFAEYIAIQSCKE-VNLDSYTRDHTKDNLQNVTRSCFELAQRRIYGLMEKDSYPRFLRSELY 581

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Medaka
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 77.0258 bits (188), Expect = 3.148e-14
Identity = 40/104 (38.46%), Postives = 60/104 (57.69%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  +  +  L N   + F++A   +Y  M+ DSY RFL+S LY
Sbjct:  403 GLAAFRAFLRTEFSEENLEFWLACEEYKKIKSQSKMASKAKKIFAEYIAIQSCKE-VNLDSYTRDHTKDNLQNVTRSCFELAQRRIYGLMEKDSYPRFLRSELY 505

[Close]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Medaka
Match: rgs3a (regulator of G protein signaling 3a [Source:ZFIN;Acc:ZDB-GENE-040801-150])

HSP 1 Score: 77.0258 bits (188), Expect = 3.166e-14
Identity = 40/104 (38.46%), Postives = 60/104 (57.69%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F+ F+  EFS ENL+FW     + KI  + KM  +A +IF  Y+  +S  + VNL++Y  +  +  L N   + F++A   +Y  M+ DSY RFL+S LY
Sbjct:  408 GLAAFRAFLRTEFSEENLEFWLACEEYKKIKSQSKMASKAKKIFAEYIAIQSCKE-VNLDSYTRDHTKDNLQNVTRSCFELAQRRIYGLMEKDSYPRFLRSELY 510

[Close]

BLAST of Regulator of G protein signaling 12a vs. Planmine SMEST
Match: SMESG000055292.1 (SMESG000055292.1)

HSP 1 Score: 1420.22 bits (3675), Expect = 0.000e+0
Identity = 766/770 (99.48%), Postives = 767/770 (99.61%), Query Frame = 2

Query:   83 MSSLNFKNVYSPILEDSHVCESIEVVSNFIINYIQTITGAQNGILSAKSLVSQKKKQFEKIYNPVSCKITKFKENRTVKIAIRRINSPNENLLNVLNVDMDEKNSQYLYLEACDDSGHNRVHIFNVINENNLKEIQLTLPSFGTKENKAQLHYFVPTNMSELVCCIHTFYLPDLGKHVSIMKEQMSDQIMNVFNKLTRKPTVLTRISNSIKLKDSFIRPKQPNSFVKFQTRSISPRFGRKNTNLERSEFKSVSIENLLSLSHDLNKQNMSLSKLDQKYSSNNALSKCYSTHSSLNGNDIDSSTXXXXXXXXXXXXXXXCGLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEIRXXXXXXXXXXXXPNKKKTFKMNIFXXXXXXXXXXXXXXXXLTTDSDVSGGNSNSPNVCEITMAYDNNKLHIVNIEPNXXXXXXXXXXXXXXXXXNFVALNLMNNEVVNFSENLSNVFHRQFIVDKSSLVRIGFVSNSLDSKLYEDFYFVVKSRNSMYLFDIVGLLSKYLPKYVGKLCLLQENNPKSVLNLCALIQDFHHSSLLIMELDLFGRAKFYGKPLRDSYETLWKRIMNDNSFQNNLPFDKNNVLDSRSDLFKKHKMNPRQVGFETINERLYRDNGNMFDDQRGLCTEDQLATPEFLKETYTNDPSKVQPEFSFSDNDTYSDVSPTQYELISDFD 2392
            MSSLNFKNVYSPILEDSHVCESIEVVSNFIINYIQTITGAQNGILSAKSLVSQKKKQFEKIYNPVSCKITKFKENRTVKIAIRRINSPNENLLNVLNVDMDEKNSQYLYLEACDDSGHNRVHIFNVINENNLKEIQLTLPSFGTKENKAQLHYFVPTNMSELVCCIHTFYLPDLGKHVSIMKEQMSDQIMNVFNKLTRKPTVLTRISNSIKLKDSFIRPKQPNSFVKFQTRSISPRFGRKNTNLERSEFKSVSIENLLSLSHDLNKQNMSLSKLDQKYSSNNALSKCYSTHSSLNGNDIDSSTEELNFFKFENFLNDE GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPC NMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEIRSLKSTKSSYSLSPNKKKTFKMNIFKSGRKSSSEISRKSSILTTDSDVSGGNSNSPNVCEITMAYDNNKLHIVNIEPNKKLIYYLKKIDKKITDINFVALNLMNNE+VNFSENLSNVFHRQFIVDKSSLVRIGFVSNSLDSKLYEDFYFVVKSRNSMYLFDIVGLLSKYLPKYVGKLCLLQENNPKSVLNLCALIQDFHHSSLLIMELDLFGRAKFYGKPLRDSYE LWKRIMNDNSFQNNLPFDKNNVLDSRSDLFKKHKMNPRQVGFETINERLYRDNGNMFDDQRGLCTEDQLATPEFLKETYTNDPSKVQPEFSFSDNDTYSDVSPTQYELISDFD
Sbjct:    1 MSSLNFKNVYSPILEDSHVCESIEVVSNFIINYIQTITGAQNGILSAKSLVSQKKKQFEKIYNPVSCKITKFKENRTVKIAIRRINSPNENLLNVLNVDMDEKNSQYLYLEACDDSGHNRVHIFNVINENNLKEIQLTLPSFGTKENKAQLHYFVPTNMSELVCCIHTFYLPDLGKHVSIMKEQMSDQIMNVFNKLTRKPTVLTRISNSIKLKDSFIRPKQPNSFVKFQTRSISPRFGRKNTNLERSEFKSVSIENLLSLSHDLNKQNMSLSKLDQKYSSNNALSKCYSTHSSLNGNDIDSSTEELNFFKFENFLNDERGLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCRNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEIRSLKSTKSSYSLSPNKKKTFKMNIFKSGRKSSSEISRKSSILTTDSDVSGGNSNSPNVCEITMAYDNNKLHIVNIEPNKKLIYYLKKIDKKITDINFVALNLMNNEIVNFSENLSNVFHRQFIVDKSSLVRIGFVSNSLDSKLYEDFYFVVKSRNSMYLFDIVGLLSKYLPKYVGKLCLLQENNPKSVLNLCALIQDFHHSSLLIMELDLFGRAKFYGKPLRDSYEALWKRIMNDNSFQNNLPFDKNNVLDSRSDLFKKHKMNPRQVGFETINERLYRDNGNMFDDQRGLCTEDQLATPEFLKETYTNDPSKVQPEFSFSDNDTYSDVSPTQYELISDFD 770

[Close]

BLAST of Regulator of G protein signaling 12a vs. Planmine SMEST
Match: SMESG000072045.1 (SMESG000072045.1)

HSP 1 Score: 70.8626 bits (172), Expect = 2.308e-12
Identity = 38/104 (36.54%), Postives = 61/104 (58.65%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            G   FQ F+ +EFS+ENL+FW  VN   K     K+++ A RI+  ++   +  + +N+++  +    K+L NP    F+ A +H+Y  +KNDSY RFL+S  Y
Sbjct:  320 GRIRFQQFLEKEFSAENLRFWATVNAH-KFGPMRKIEESAKRIYTEFLGNNATSE-INVDSRTMAATEKELKNPSRFTFEEAQDHIYTLVKNDSYVRFLRSDDY 421

[Close]

BLAST of Regulator of G protein signaling 12a vs. Planmine SMEST
Match: SMESG000048981.1 (SMESG000048981.1)

HSP 1 Score: 69.3218 bits (168), Expect = 7.335e-12
Identity = 37/134 (27.61%), Postives = 70/134 (52.24%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLYDSWRNEIRXXXXXXXXXXXXPNKKKTFKMN 1441
            GL  F  ++  E+S EN++FW     F  I + +KM   A +I   ++  ++  + VN+++   +   + + +P  NMFD+A   +   M+ DSY RFL+S +Y +   +I+     +   +  P+ K T K++
Sbjct:  360 GLALFHDYLKSEYSEENIEFWIACEEFKTITNPKKMASRAQKIIKDFVTTQAPKE-VNIDSKTRQITLESIQHPNANMFDMAQKRIQSLMEIDSYQRFLRSEMYQALMQDIKKASIPEPVPNSLPSMKPTSKIH 492

[Close]

BLAST of Regulator of G protein signaling 12a vs. Planmine SMEST
Match: SMESG000053355.1 (SMESG000053355.1)

HSP 1 Score: 64.6994 bits (156), Expect = 1.382e-11
Identity = 36/104 (34.62%), Postives = 58/104 (55.77%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL YF  F+  E+S ENL FW     F  I   +K+ + A  I+  Y+   SE++ VNL+  +  +  +++ +P   +F++A + ++  M  DSY RFLKS  Y
Sbjct:   76 GLYYFNEFLKSEYSVENLNFWLACEKFKTIQSRKKLDEIANSIYQEYIAIGSENE-VNLDAKLRRNIIEQMNSPNKKLFELAQSSIFILMAKDSYCRFLKSKCY 178

[Close]

BLAST of Regulator of G protein signaling 12a vs. Planmine SMEST
Match: SMESG000027589.1 (SMESG000027589.1)

HSP 1 Score: 66.2402 bits (160), Expect = 3.560e-11
Identity = 33/104 (31.73%), Postives = 57/104 (54.81%), Query Frame = 2

Query: 1040 GLKYFQIFVSREFSSENLKFWQEVNTFSKILDEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDIASNHVYQTMKNDSYTRFLKSSLY 1351
            GL  F  F+  E+S ENL+FW    ++  +  ++K+ KEA +I++ ++  ++  + VNL++         L  P    FD A   ++  M+ DSY RFL+S +Y
Sbjct:  222 GLALFNAFLKTEYSDENLEFWMACESYKSLSGQKKLYKEAQKIYSQHLSVQAP-REVNLDSKTRLQTISSLGTPSKMTFDSAQKRIFALMEKDSYPRFLRSDIY 324

The following BLAST results are available for this feature:

BLAST of Regulator of G protein signaling 12a vs. Ensembl Human
BLAST of Regulator of G protein signaling 12a vs. Ensembl Celegans
BLAST of Regulator of G protein signaling 12a vs. Ensembl Fly
BLAST of Regulator of G protein signaling 12a vs. Ensembl Zebrafish
BLAST of Regulator of G protein signaling 12a vs. Ensembl Xenopus
BLAST of Regulator of G protein signaling 12a vs. Ensembl Mouse
BLAST of Regulator of G protein signaling 12a vs. UniProt/SwissProt
BLAST of Regulator of G protein signaling 12a vs. TrEMBL
BLAST of Regulator of G protein signaling 12a vs. Ensembl Cavefish
BLAST of Regulator of G protein signaling 12a vs. Ensembl Sea Lamprey
BLAST of Regulator of G protein signaling 12a vs. Ensembl Yeast
BLAST of Regulator of G protein signaling 12a vs. Ensembl Nematostella
BLAST of Regulator of G protein signaling 12a vs. Ensembl Medaka
BLAST of Regulator of G protein signaling 12a vs. Planmine SMEST

BLAST of Regulator of G protein signaling 12a vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RGS3	1.002e-15	38.46	regulator of G protein signaling 3 [Source:HGNC Sy...	[more]
RGS8	1.343e-15	37.50	regulator of G protein signaling 8 [Source:HGNC Sy...	[more]
RGS8	1.343e-15	37.50	regulator of G protein signaling 8 [Source:HGNC Sy...	[more]
RGS8	1.343e-15	37.50	regulator of G protein signaling 8 [Source:HGNC Sy...	[more]
RGS3	1.696e-15	38.46	regulator of G protein signaling 3 [Source:HGNC Sy...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egl-10	4.290e-13	36.54	Regulator of G-protein signaling egl-10 [Source:U...	[more]
egl-10	4.445e-13	36.54	Regulator of G-protein signaling egl-10 [Source:U...	[more]
egl-10	4.858e-13	36.54	Regulator of G-protein signaling egl-10 [Source:U...	[more]
rgs-2	2.021e-12	33.64	Regulator of G-protein signaling rgs-2 [Source:Un...	[more]
rgs-2	2.988e-12	33.64	Regulator of G-protein signaling rgs-2 [Source:Un...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RSG7	6.226e-14	34.82	gene:FBgn0024941 transcript:FBtr0074350	[more]
RSG7	6.226e-14	34.82	gene:FBgn0024941 transcript:FBtr0307538	[more]
CG42450	2.042e-9	32.38	gene:FBgn0259927 transcript:FBtr0310343	[more]
CG42450	2.063e-9	32.38	gene:FBgn0259927 transcript:FBtr0300218	[more]
loco	4.334e-9	31.13	gene:FBgn0020278 transcript:FBtr0084273	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rgs3b	1.497e-16	38.39	regulator of G protein signaling 3b [Source:ZFIN;A...	[more]
rgs3b	2.746e-15	38.39	regulator of G protein signaling 3b [Source:ZFIN;A...	[more]
RGS13	3.021e-15	34.91	si:ch211-117l17.5 [Source:ZFIN;Acc:ZDB-GENE-110914...	[more]
BX936311.1	6.759e-15	34.91	si:ch211-117l17.5 [Source:NCBI gene;Acc:792554]	[more]
RGS13	9.406e-15	34.91	si:ch211-117l17.5 [Source:ZFIN;Acc:ZDB-GENE-110914...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cipc	4.681e-13	33.33	CLOCK-interacting pacemaker [Source:Xenbase;Acc:XB...	[more]
cipc	4.729e-13	33.65	CLOCK-interacting pacemaker [Source:Xenbase;Acc:XB...	[more]
rgs18	7.831e-13	37.74	regulator of G-protein signaling 18 [Source:NCBI g...	[more]
nhlrc3	1.375e-12	32.38	NHL repeat containing 3 [Source:Xenbase;Acc:XB-GEN...	[more]
ENSXETT00000026168.1	8.208e-12	36.45	regulator of G-protein signaling 14 [Source:NCBI g...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rgs3	2.411e-16	37.50	regulator of G-protein signaling 3 [Source:MGI Sym...	[more]
Rgs8	2.145e-15	36.54	regulator of G-protein signaling 8 [Source:MGI Sym...	[more]
Rgs8	2.145e-15	36.54	regulator of G-protein signaling 8 [Source:MGI Sym...	[more]
Rgs8	2.145e-15	36.54	regulator of G-protein signaling 8 [Source:MGI Sym...	[more]
Rgs3	2.169e-15	37.50	regulator of G-protein signaling 3 [Source:MGI Sym...	[more]

BLAST of Regulator of G protein signaling 12a vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P57771\|RGS8_HUMAN	6.449e-15	37.50	Regulator of G-protein signaling 8 OS=Homo sapiens...	[more]
sp\|P49804\|RGS8_RAT	1.458e-14	36.54	Regulator of G-protein signaling 8 OS=Rattus norve...	[more]
sp\|Q8BXT1\|RGS8_MOUSE	1.501e-14	36.54	Regulator of G-protein signaling 8 OS=Mus musculus...	[more]
sp\|Q95K68\|RGS8_MACFA	3.081e-14	36.54	Regulator of G-protein signaling 8 OS=Macaca fasci...	[more]
sp\|P49796\|RGS3_HUMAN	1.498e-13	38.46	Regulator of G-protein signaling 3 OS=Homo sapiens...	[more]

BLAST of Regulator of G protein signaling 12a vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2P6MVJ3	3.342e-14	37.84	Regulator of G-protein signaling 21 OS=Planoprotos...	[more]
A0A2P6N4X4	4.052e-14	37.84	Uncharacterized protein OS=Planoprotostelium fungi...	[more]
A0A3M7QPA7	5.207e-14	41.35	Regulator of G-signaling 14-like isoform X1 (Fragm...	[more]
A0A2I0T5P5	5.275e-14	41.35	RGS domain-containing protein OS=Limosa lapponica ...	[more]
A0A091KUV7	7.130e-14	41.35	Regulator of G-protein signaling 3 (Fragment) OS=C...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rgs3a	1.299e-16	40.38	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]
rgs3a	2.348e-16	40.38	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]
rgs3a	1.778e-15	40.38	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]
rgs3a	2.007e-15	40.38	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]
rgs3a	2.017e-15	40.38	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000006812.1	6.840e-16	36.54	pep scaffold:Pmarinus_7.0:GL476397:246833:248901:1...	[more]
RGS7	2.041e-13	35.24	regulator of G protein signaling 7 [Source:HGNC Sy...	[more]
ENSPMAT00000010442.1	2.816e-13	35.58	pep scaffold:Pmarinus_7.0:GL482357:13581:16779:-1 ...	[more]
ENSPMAT00000010441.1	1.021e-12	36.54	pep scaffold:Pmarinus_7.0:GL482357:13581:16779:-1 ...	[more]
ENSPMAT00000010444.1	1.423e-12	36.19	pep scaffold:Pmarinus_7.0:GL482357:14059:16996:-1 ...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Regulator of G protein signaling 12a vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO43126	8.298e-16	40.38	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34351	3.946e-13	37.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32804	1.852e-11	31.73	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37370	7.344e-10	30.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Regulator of G protein signaling 12a vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rgs14a	3.044e-15	41.67	regulator of G protein signaling 14 [Source:NCBI g...	[more]
rgs14a	4.249e-15	41.67	regulator of G protein signaling 14 [Source:NCBI g...	[more]
rgs3a	3.085e-14	38.46	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]
rgs3a	3.148e-14	38.46	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]
rgs3a	3.166e-14	38.46	regulator of G protein signaling 3a [Source:ZFIN;A...	[more]

BLAST of Regulator of G protein signaling 12a vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000055292.1	0.000e+0	99.48	SMESG000055292.1	[more]
SMESG000072045.1	2.308e-12	36.54	SMESG000072045.1	[more]
SMESG000048981.1	7.335e-12	27.61	SMESG000048981.1	[more]
SMESG000053355.1	1.382e-11	34.62	SMESG000053355.1	[more]
SMESG000027589.1	3.560e-11	31.73	SMESG000027589.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030346 ID=SMED30030346|Name=Regulator of G protein signaling 12a|organism=Schmidtea mediterranea sexual|type=transcript|length=2643bp
AAAGAATTTTATTTTATGAAATATTATACTTTTTACTTAAAAATGTATCC
GATTTATTAAATTAGAAAATTGTTAATTATTTATGAGTTCTCTTAATTTT
AAAAATGTCTATTCGCCTATTTTGGAAGATAGTCATGTTTGTGAATCAAT
AGAAGTGGTCTCAAACTTCATTATTAACTATATTCAAACAATTACAGGAG
CCCAAAATGGTATACTATCTGCCAAATCTTTAGTTAGTCAAAAGAAAAAA
CAATTTGAAAAAATATACAATCCTGTAAGCTGCAAAATTACAAAATTTAA
AGAAAACAGAACAGTTAAAATTGCTATACGTAGAATTAATTCTCCAAATG
AAAATTTATTAAATGTATTAAATGTCGATATGGATGAAAAAAACTCACAA
TACTTATATCTGGAAGCTTGTGACGATTCAGGTCATAATCGCGTACACAT
TTTCAACGTCATTAATGAAAATAACTTGAAGGAAATCCAACTAACATTGC
CTTCCTTTGGAACAAAAGAAAATAAAGCACAGCTTCATTATTTTGTACCT
ACCAATATGTCGGAACTTGTGTGTTGTATTCATACATTTTATCTACCAGA
TTTAGGGAAGCATGTTTCGATAATGAAAGAACAAATGTCTGATCAAATTA
TGAATGTGTTTAATAAATTAACCCGTAAGCCAACAGTGCTAACACGAATT
TCAAATTCCATTAAATTAAAAGATTCTTTCATCAGACCGAAACAACCTAA
TAGTTTTGTGAAATTTCAAACTCGCTCTATAAGTCCTAGATTTGGACGAA
AAAATACAAATTTGGAAAGATCAGAGTTTAAATCTGTAAGCATTGAAAAT
TTGTTATCACTCAGTCATGATTTAAATAAACAAAATATGAGTTTATCGAA
ATTGGATCAAAAATACAGCAGTAACAACGCATTATCGAAATGCTATTCGA
CCCATTCATCATTGAATGGTAACGACATTGACTCATCTACTGAGGAATTG
AATTTTTTTAAATTCGAAAACTTTCTCAATGATGAATGTGGATTAAAATA
TTTCCAAATTTTCGTTTCCAGGGAATTTAGTTCAGAAAATTTAAAATTTT
GGCAAGAAGTTAATACATTTTCTAAAATCCTTGATGAAGAAAAGATGAAA
AAAGAAGCTTATCGGATTTTTAATACTTATATGGATCCTAAAAGTGAAGA
TCAGACTGTAAATCTGGAGAATTATATTATAGAAGATGCTAGAAAGAAAT
TAACGAATCCTTGCATGAATATGTTTGATATTGCTAGCAACCATGTCTAT
CAAACAATGAAAAATGATTCATATACCAGATTTTTGAAATCATCACTATA
TGATTCCTGGAGAAATGAAATAAGAAGTCTGAAATCCACTAAATCTTCTT
ACTCGTTATCTCCAAATAAAAAGAAAACATTTAAAATGAATATTTTTAAA
AGTGGACGTAAATCGAGTTCAGAAATATCAAGGAAATCATCAATTTTGAC
AACTGATTCTGATGTGAGTGGCGGCAATTCAAATTCGCCCAACGTCTGTG
AGATTACTATGGCTTATGATAATAATAAATTGCACATTGTTAATATCGAA
CCAAATAAAAAACTGATTTATTATCTGAAAAAAATCGATAAAAAAATCAC
CGACATTAATTTTGTGGCTTTGAACTTGATGAACAATGAAGTAGTAAATT
TTTCTGAAAACTTATCCAATGTTTTTCATCGGCAATTTATTGTTGATAAA
TCTTCTCTTGTCAGAATTGGTTTCGTTTCAAATTCGCTCGATTCTAAATT
GTACGAAGATTTTTATTTCGTCGTTAAATCCAGAAATTCTATGTATCTAT
TTGATATTGTTGGATTACTGAGCAAATATTTACCGAAATATGTTGGTAAA
TTATGTCTTTTACAGGAAAATAATCCAAAGTCCGTATTAAATTTATGTGC
ATTAATTCAAGATTTTCATCATTCTTCATTGCTTATCATGGAATTAGATT
TATTTGGAAGAGCAAAATTCTATGGTAAGCCCCTGAGGGACTCATATGAA
ACATTGTGGAAAAGAATTATGAATGATAATTCTTTCCAAAATAATTTACC
ATTTGATAAGAATAATGTTTTAGATTCACGGTCTGATCTTTTTAAGAAAC
ATAAAATGAATCCGAGACAAGTTGGATTTGAAACAATAAATGAAAGATTG
TATCGAGATAATGGAAATATGTTTGATGATCAGCGTGGCCTGTGTACTGA
AGATCAATTGGCAACTCCCGAATTTCTGAAAGAAACTTATACAAATGATC
CGAGTAAAGTTCAGCCAGAATTTAGTTTTTCTGATAACGATACGTACTCT
GATGTTTCTCCAACTCAATATGAATTGATAAGTGATTTTGATTAAAAACT
TTATTCATTGAGATAGTGTGTTTTACTGGTGTCTTTCTCTCAGAAATAAT
TCGTTGTGCAATATCGGTTTCAGTTGTAATTTTGTTGTCTTGGTTAAACC
TGCCATGTTAAATTAGCCATGTCATTTCAATTTACTGATTTTCTATTTGT
TTCAATTTCCTACTGCTGTTTACCAGATAGATATACGATACAATATATTT
TCTTTATACTCTTTTCTAATAAACTTTATTAATTGAAAAAAAA

protein sequence of SMED30030346-orf-1

>SMED30030346-orf-1 ID=SMED30030346-orf-1|Name=SMED30030346-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=771bp
MSSLNFKNVYSPILEDSHVCESIEVVSNFIINYIQTITGAQNGILSAKSL
VSQKKKQFEKIYNPVSCKITKFKENRTVKIAIRRINSPNENLLNVLNVDM
DEKNSQYLYLEACDDSGHNRVHIFNVINENNLKEIQLTLPSFGTKENKAQ
LHYFVPTNMSELVCCIHTFYLPDLGKHVSIMKEQMSDQIMNVFNKLTRKP
TVLTRISNSIKLKDSFIRPKQPNSFVKFQTRSISPRFGRKNTNLERSEFK
SVSIENLLSLSHDLNKQNMSLSKLDQKYSSNNALSKCYSTHSSLNGNDID
SSTEELNFFKFENFLNDECGLKYFQIFVSREFSSENLKFWQEVNTFSKIL
DEEKMKKEAYRIFNTYMDPKSEDQTVNLENYIIEDARKKLTNPCMNMFDI
ASNHVYQTMKNDSYTRFLKSSLYDSWRNEIRSLKSTKSSYSLSPNKKKTF
KMNIFKSGRKSSSEISRKSSILTTDSDVSGGNSNSPNVCEITMAYDNNKL
HIVNIEPNKKLIYYLKKIDKKITDINFVALNLMNNEVVNFSENLSNVFHR
QFIVDKSSLVRIGFVSNSLDSKLYEDFYFVVKSRNSMYLFDIVGLLSKYL
PKYVGKLCLLQENNPKSVLNLCALIQDFHHSSLLIMELDLFGRAKFYGKP
LRDSYETLWKRIMNDNSFQNNLPFDKNNVLDSRSDLFKKHKMNPRQVGFE
TINERLYRDNGNMFDDQRGLCTEDQLATPEFLKETYTNDPSKVQPEFSFS
DNDTYSDVSPTQYELISDFD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction
GO:0050790	regulation of catalytic activity
GO:0000188	inactivation of MAPK activity
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0009968	negative regulation of signal transduction
GO:0043547	positive regulation of GTPase activity

Vocabulary: **molecular function**
Term	Definition
GO:0030695	GTPase regulator activity
GO:0005096	GTPase activator activity
GO:0005515	protein binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036305	RGS_sf
IPR016137	RGS
IPR024066	RGS_subdom1/3

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR016137	RGS domain	PRINTS	PR01301	RGSPROTEIN	coord: 401..420 score: 51.85 coord: 329..347 score: 41.99 coord: 307..328 score: 28.75
IPR016137	RGS domain	SMART	SM00315	RGS_3	coord: 310..427 e-value: 3.5E-33 score: 126.2
IPR016137	RGS domain	PFAM	PF00615	RGS	coord: 311..425 e-value: 8.3E-27 score: 93.8
IPR016137	RGS domain	PROSITE	PS50132	RGS	coord: 310..427 score: 31.604
None	No IPR available	GENE3D	G3DSA:1.20.58.1850		coord: 289..430 e-value: 3.7E-31 score: 109.6
None	No IPR available	PANTHER	PTHR45945	FAMILY NOT NAMED	coord: 238..475
IPR036305	RGS domain superfamily	SUPERFAMILY	SSF48097	Regulator of G-protein signaling, RGS	coord: 308..424

Main menu

Regulator of G protein signaling 12a

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Owlery

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