Leucine-rich repeat and WD repeat-containing protein 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030320 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Human
Match: LRWD1 (leucine rich repeats and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21769]) HSP 1 Score: 204.527 bits (519), Expect = 2.428e-54 Identity = 137/427 (32.08%), Postives = 209/427 (48.95%), Query Frame = 1
Query: 4483 PNPQCKGISVNGK-----TPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMA--GGH--YINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLT-------KLMCPRAHLNPVLNLVVMPSYDA-LITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPC---FDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWS 5703
P+ Q +G V G +PLHF++CH+++N+P D T++W CAFEP T+ VATCGGE VC+IDC+TG V+ ++K+ EEF++VAWT + + GH ++LAAAG +RLLH C ++ H++ IA + F P + T LF+ +++WDIG+P+ QLLT +CP V DA L+ GCE G W + R +P + + E E DGLA ++E K G I ++ Q + R Q+ + V+ +L+W T+ Y +++A + G V CGD EG +WLYD+S + + P +IL WP+ + V K ++N V ++ TYL A+TD+N+V IW
Sbjct: 252 PSAQVEGSPVAGSDGSQPAVKLEPLHFLQCHSKNNSPQDLETQLWACAFEPAWEEG--ATSQTVATCGGEAVCVIDCQTGIVLHKYKAPGEEFFSVAWTALMVVTQAGHKKRWSVLAAAGLRGLVRLLHVRAGFCCGVIRAHKKAIATLCFSPAHETHLFTASYDKRIILWDIGVPNQDYEFQASQLLTLDTTSIPLRLCP-----------VASCPDARLLAGCEGGCCCW---DVRLDQPQKRRVCEVEFVFSEGSEASGRRVDGLAFVNEDIVASKGSGLGTICLWSWRQT---WGGR--GSQSTVAVVVLARLQWSSTELAYFSLSACPDKGIVLCGDEEGNVWLYDVSNILKQPPLLPAALQAPTQILKWPQPWALG-----------QVVTKT-MVNTVVANASFTYLTALTDSNIVAIWG 645
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Human
Match: LRWD1 (leucine rich repeats and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21769]) HSP 1 Score: 74.7146 bits (182), Expect = 8.782e-14 Identity = 72/269 (26.77%), Postives = 112/269 (41.64%), Query Frame = 1
Query: 4957 VLMWDIGIPSAPEYTTHYQLLTK-------LMCPRAHLNPVLNLVVMPSYDA-LITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPC---FDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKF---------KCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWS 5703
+++WDIG+P+ QLLT +CP A DA L+ GCE G W + R +P + + E E DGLA ++E K G I ++ Q + R Q+ + V+ +L+W T+ Y +++A + G V CGD EG +WLYD+S + + P +IL WP+ + V K ++N V ++ TYL A+TD+N+V IW
Sbjct: 3 IILWDIGVPNQDYEFQASQLLTLDTTSIPLRLCPVASCP-----------DARLLAGCEGGCCCW---DVRLDQPQKRRVCEVEFVFSEGSEASGRRVDGLAFVNEDIVASKGSGLGTICLWSW---RQTWGGR--GSQSTVAVVVLARLQWSSTELAYFSLSACPDKGIVLCGDEEGNVWLYDVSNILKQPPLLPAALQAPTQPSPPLSPHQILKWPQPWALG-----------QVVTKT-MVNTVVANASFTYLTALTDSNIVAIWG 240
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Human
Match: EED (embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188]) HSP 1 Score: 57.3806 bits (137), Expect = 1.840e-7 Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 112 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 220
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Human
Match: EED (embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188]) HSP 1 Score: 56.9954 bits (136), Expect = 3.097e-7 Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 112 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 220
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Human
Match: EED (embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188]) HSP 1 Score: 56.6102 bits (135), Expect = 3.334e-7 Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 112 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 220
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Fly
Match: escl (gene:FBgn0032391 transcript:FBtr0342581) HSP 1 Score: 57.7658 bits (138), Expect = 7.313e-8 Identity = 39/128 (30.47%), Postives = 62/128 (48.44%), Query Frame = 1
Query: 4630 NPYLETTS--VVATCGGECVCLIDCR--TG-------KVMKRFKS--REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
NP+L+ V AT G + V + +C TG ++++ + +E FYT AW+ + G +LAAAG IR+ +P + C GH I + FHP P +L SG ++ +W+I
Sbjct: 117 NPFLDRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSYDSVTGD---PVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNI 241
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Fly
Match: escl (gene:FBgn0032391 transcript:FBtr0080286) HSP 1 Score: 57.7658 bits (138), Expect = 7.313e-8 Identity = 39/128 (30.47%), Postives = 62/128 (48.44%), Query Frame = 1
Query: 4630 NPYLETTS--VVATCGGECVCLIDCR--TG-------KVMKRFKS--REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
NP+L+ V AT G + V + +C TG ++++ + +E FYT AW+ + G +LAAAG IR+ +P + C GH I + FHP P +L SG ++ +W+I
Sbjct: 117 NPFLDRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSYDSVTGD---PVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNI 241
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Zebrafish
Match: lrwd1 (leucine-rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:327124]) HSP 1 Score: 203.756 bits (517), Expect = 1.588e-53 Identity = 119/400 (29.75%), Postives = 211/400 (52.75%), Query Frame = 1
Query: 4537 PLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPY--LETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMA--GGHY--INILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVWLFP----EFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
PLH ++CH+R N+P D +T++W CAFEP ++ + +ATCGGE +C+I+C +G V+K++K E+F+++AW+TV M+ GG NILAA GK ++L+HP + + E + + I+ M F+PR PT LF+G + +WDIG + +++ ++KL+ P L+L ++PS L++GC++G++ + ++++ +I P ++ + DGL+ LS+ K +G I+ ++ + +RK + A ++ +L+W TD Y+++ G V CGD +G +W+Y ++ + EN + K ++L WP + + + P IN M YLVA+TD N+V +W
Sbjct: 380 PLHVLQCHSRQNDPDDFSTQLWACAFEPQQDDSIDISGGSQTIATCGGETLCVINCESGLVLKKYKVPGEDFFSLAWSTVLMSRTGGSARPCNILAAGGKRGCVKLIHPRVNLAFGEFRVSRRAISIMRFNPRKPTFLFTGTYDKKIFLWDIG---GLDQDYNFK-ISKLLTLETSSTP-LHLALLPSSPDTHLLSGCDEGLYCFDVQLSKNTLKRNEEIEIVFPIYKKNDKKNNYRTIDGLSFLSDDVVASKSHMQGSIYLWSWSATRASWNSRK----KEVPAVILAELQWSSTDIPYLSLGTCPGYGYVVCGDEQGRLWMYHITDTMMENFKSGK-TISATEVLQWPSPI-----------RAGKGALEGPSINSTAMDPGLHYLVALTDKNMVVVW 758
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Zebrafish
Match: lrwd1 (leucine-rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:327124]) HSP 1 Score: 203.756 bits (517), Expect = 1.662e-53 Identity = 119/400 (29.75%), Postives = 211/400 (52.75%), Query Frame = 1
Query: 4537 PLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPY--LETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMA--GGHY--INILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVWLFP----EFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
PLH ++CH+R N+P D +T++W CAFEP ++ + +ATCGGE +C+I+C +G V+K++K E+F+++AW+TV M+ GG NILAA GK ++L+HP + + E + + I+ M F+PR PT LF+G + +WDIG + +++ ++KL+ P L+L ++PS L++GC++G++ + ++++ +I P ++ + DGL+ LS+ K +G I+ ++ + +RK + A ++ +L+W TD Y+++ G V CGD +G +W+Y ++ + EN + K ++L WP + + + P IN M YLVA+TD N+V +W
Sbjct: 385 PLHVLQCHSRQNDPDDFSTQLWACAFEPQQDDSIDISGGSQTIATCGGETLCVINCESGLVLKKYKVPGEDFFSLAWSTVLMSRTGGSARPCNILAAGGKRGCVKLIHPRVNLAFGEFRVSRRAISIMRFNPRKPTFLFTGTYDKKIFLWDIG---GLDQDYNFK-ISKLLTLETSSTP-LHLALLPSSPDTHLLSGCDEGLYCFDVQLSKNTLKRNEEIEIVFPIYKKNDKKNNYRTIDGLSFLSDDVVASKSHMQGSIYLWSWSATRASWNSRK----KEVPAVILAELQWSSTDIPYLSLGTCPGYGYVVCGDEQGRLWMYHITDTMMENFKSGK-TISATEVLQWPSPI-----------RAGKGALEGPSINSTAMDPGLHYLVALTDKNMVVVW 763
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Zebrafish
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550463]) HSP 1 Score: 54.6842 bits (130), Expect = 9.264e-7 Identity = 35/112 (31.25%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + + H +LA AG IR+++ + C GH I + FHPR P +L S + +W+I
Sbjct: 114 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-FDCSSSH--PLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 222
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Xenopus
Match: lrwd1 (leucine-rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:100145159]) HSP 1 Score: 194.897 bits (494), Expect = 6.400e-51 Identity = 135/410 (32.93%), Postives = 208/410 (50.73%), Query Frame = 1
Query: 4534 DPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS--VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGG----HYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEP-------CFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKC----KPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
+PLHF++CH+++N+ D T++W CAFEP L+++S VATCGG+ VC+IDC TGKVMK++K EEF+T+ WTT+ M G IN+LAA GK +R++H + +CY E+K H++ I+ M F P+ T LF+G +++WDIG+P QLLT + L + ++PS + L+ CEDG F W + R K + + E+ P ++E D LA L+E +K + I+ + L + R+ +I+ + + + + Y + V CGD +G IW+YD+ + + + R C +P KIL WP + E V K +IN V + YLVA+TD N+V IW I
Sbjct: 311 EPLHFLQCHSKNNSCEDFKTQLWACAFEP-----ILDSSSPKAVATCGGDSVCIIDCETGKVMKKYKVTGEEFFTLVWTTLTMIGKDEQKRKINVLAAGGKHGVVRIIHAKVSLCYGEIKAHKKAISIMCFSPKQDTFLFTGSYDKRIILWDIGVPDCDYNFRPSQLLT-----LDTTSVPLRMCLVPSCPDEFLVAACEDGCFAW---DIRLDKKQGRRSYEVELNFPIYKEERKDNDFHVIDSLAFLNEDIIDMKRNMQKYIYIYIYIHTLLN---RENANTKKIIKIIFTKKNFTSKEAPYPYRSQTRERYCVFCGDEDGKIWIYDL--DSCKADLQRGKLCSVVKEPTKILSWP-----------ILFSPKEKVEKT-LINVVTVDPTMEYLVALTDINIVSIWKI 690
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Xenopus
Match: lrwd1 (leucine-rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:100145159]) HSP 1 Score: 189.119 bits (479), Expect = 3.185e-49 Identity = 128/405 (31.60%), Postives = 201/405 (49.63%), Query Frame = 1
Query: 4528 DYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS--VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGG----HYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKC----KPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
+ +PLHF++CH+++N+ D T++W CAFEP L+++S VATCGG+ VC+IDC TGKVMK++K EEF+T+ WTT+ M G IN+LAA GK +R++H + +CY E+K H++ I+ M F P+ T LF+G +++WDIG+P QLLT + L + ++PS + L+ CEDG F W ++++ Q + + R + + V +G ++ + L A ++ +++ T +I T + V CGD +G IW+YD+ + + + R C +P KIL WP + E V K +IN V + YLVA+TD N+V IW I
Sbjct: 309 NIEPLHFLQCHSKNNSCEDFKTQLWACAFEP-----ILDSSSPKAVATCGGDSVCIIDCETGKVMKKYKVTGEEFFTLVWTTLTMIGKDEQKRKINVLAAGGKHGVVRIIHAKVSLCYGEIKAHKKAISIMCFSPKQDTFLFTGSYDKRIILWDIGVPDCDYNFRPSQLLT-----LDTTSVPLRMCLVPSCPDEFLVAACEDGCFAW------------------DIRLDKKQGRRYIYINRRVQK---ISKVVQGFVYLCHTCVNLD--------------AMLLALFKFKSTLMSFIFFTERY---CVFCGDEDGKIWIYDL--DSCKADLQRGKLCSVVKEPTKILSWP-----------ILFSPKEKVEKT-LINVVTVDPTMEYLVALTDINIVSIWKI 651
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Xenopus
Match: lrwd1 (leucine-rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:100145159]) HSP 1 Score: 171.785 bits (434), Expect = 2.111e-43 Identity = 85/208 (40.87%), Postives = 127/208 (61.06%), Query Frame = 1
Query: 4528 DYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS--VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGG----HYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVW 5127
+ +PLHF++CH+++N+ D T++W CAFEP L+++S VATCGG+ VC+IDC TGKVMK++K EEF+T+ WTT+ M G IN+LAA GK +R++H + +CY E+K H++ I+ M F P+ T LF+G +++WDIG+P QLLT + L + ++PS + L+ CEDG F W
Sbjct: 344 NIEPLHFLQCHSKNNSCEDFKTQLWACAFEP-----ILDSSSPKAVATCGGDSVCIIDCETGKVMKKYKVTGEEFFTLVWTTLTMIGKDEQKRKINVLAAGGKHGVVRIIHAKVSLCYGEIKAHKKAISIMCFSPKQDTFLFTGSYDKRIILWDIGVPDCDYNFRPSQLLT-----LDTTSVPLRMCLVPSCPDEFLVAACEDGCFAW 541
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Xenopus
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550079]) HSP 1 Score: 57.7658 bits (138), Expect = 1.587e-7 Identity = 35/110 (31.82%), Postives = 53/110 (48.18%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTG---KVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C ++++ + +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 116 VFATVGSNRVTLYECHPQGEIRLLQSYVDADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 222
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Xenopus
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550079]) HSP 1 Score: 57.3806 bits (137), Expect = 1.812e-7 Identity = 35/110 (31.82%), Postives = 53/110 (48.18%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTG---KVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C ++++ + +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 117 VFATVGSNRVTLYECHPQGEIRLLQSYVDADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 223
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Mouse
Match: Lrwd1 (leucine-rich repeats and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:1918985]) HSP 1 Score: 206.453 bits (524), Expect = 3.993e-55 Identity = 136/400 (34.00%), Postives = 208/400 (52.00%), Query Frame = 1
Query: 4534 DPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS-VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWT--TVEMAGGH--YINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDD--IQHPDF----EVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
+PLHF++CH+R+N+P D T++W CAFEP + TS VATCGGE VC+IDC+TG V+ ++K EEF++VAWT TV GH N+LAAAG +RLLH C + ++ H++ IA + F P + T LF+ +++WDIG+P+ QLLT L C L L V D L+ GCE G + W + R +P + +F + KV + DGLA ++E K +G I+ ++ Q + R Q+ + ++ +L+W T+ Y +++ V CGD EG++W+YD+ + E + P +IL WP+ + + V K +IN V ++ TYL A+TD+N+V IW
Sbjct: 273 EPLHFLQCHSRNNSPKDLETQLWACAFEPAREEGHSRATSQTVATCGGEAVCVIDCQTGLVLHKYKVPGEEFFSVAWTALTVVTQAGHKKRWNMLAAAGLRGMVRLLHVRAGFCCSVIRAHKKAIATLCFSPSHETHLFTASYDKRIILWDIGVPNQDYKFQASQLLT-LNCGSVPLR--LCPVATCPDDFLLAGCEGGCYCW---DVRLDQPQKQRVCEVNFIFSEDSKVSGQR---VDGLAFVNEDVVASKGSGQGTIYLWSWSQT---WAGR--GRQSVLPVVILVRLQWSPTNLAYFSLSTCPGKNLVLCGDEEGSVWIYDVEHLLKEPPQATTLQ-PPTQILKWPQPTALG-----------QPVTKT-MINTVVANAAFTYLTALTDSNIVSIW 645
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286]) HSP 1 Score: 56.6102 bits (135), Expect = 5.816e-8 Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 61 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 169
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286]) HSP 1 Score: 56.6102 bits (135), Expect = 2.289e-7 Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 112 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 220
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286]) HSP 1 Score: 56.6102 bits (135), Expect = 2.289e-7 Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 112 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 220
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Mouse
Match: Eed (embryonic ectoderm development [Source:MGI Symbol;Acc:MGI:95286]) HSP 1 Score: 56.225 bits (134), Expect = 3.334e-7 Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 171 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDSNTSH--PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 279
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q6GM71|LRWD1_XENLA (Leucine-rich repeat and WD repeat-containing protein 1 OS=Xenopus laevis OX=8355 GN=lrwd1 PE=2 SV=1) HSP 1 Score: 237.269 bits (604), Expect = 4.056e-64 Identity = 144/409 (35.21%), Postives = 220/409 (53.79%), Query Frame = 1
Query: 4534 DPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGG----HYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQE----PCF---DGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKC----KPAKILDWP-ECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
+PLHF++CH+++N+ D T++W CAFEPN ++ VATCGG+ +C+IDC TGKVMK++K EEF+T+ WTT+ M G IN+LAA GK +R++H + +CY E+K H++ I+ M F P+ T LF+G +++WDIG+P QLLT + L + V+PS + L+ CEDG F W + K + + E P ++E CF D LA L+E K V +G I+ ++ + L K+RK ++ A ++ Q++W ++ Y+ ++ V CGD +G IW+YD+ + + + R C +P KIL WP CS Q +TV+K +IN V + YLVA+TD N+V IW I
Sbjct: 341 EPLHFLQCHSKNNSCEDFKTQLWACAFEPNLDS---SCPKAVATCGGDSICIIDCETGKVMKKYKVTGEEFFTLVWTTLTMIGKDGQKRKINVLAAGGKYGVVRMIHAKGSLCYGEIKAHKKAISIMCFSPKQETFLFTGSYDKRIILWDIGVPDCDYNFRPSQLLT-----LDTTSVPLRMCVVPSCPDEFLVAACEDGCFAW---DIGLDKKQGRRSHEVEFNFPLYKEERKDKCFHIIDSLAFLNEDIIASKSVMQGSIYLWSWEKTL---KSRKNKNVKKLDAVILSQMKWSSSETPYLVLSTSPERDCVFCGDEDGKIWIYDL--DSCKADLQRGKLCSTVKEPTKILSWPLLCS-----------QKEKTVDKT-LINVVTVDPTMEYLVALTDINIVSIWKI 721
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. UniProt/SwissProt
Match: sp|B0JZ65|LRWD1_XENTR (Leucine-rich repeat and WD repeat-containing protein 1 OS=Xenopus tropicalis OX=8364 GN=lrwd1 PE=2 SV=1) HSP 1 Score: 231.106 bits (588), Expect = 3.286e-62 Identity = 141/412 (34.22%), Postives = 218/412 (52.91%), Query Frame = 1
Query: 4528 DYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS--VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGG----HYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEP-------CFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKC----KPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
+ +PLHF++CH+++N+ D T++W CAFEP L+++S VATCGG+ VC+IDC TGKVMK++K EEF+T+ WTT+ M G IN+LAA GK +R++H + +CY E+K H++ I+ M F P+ T LF+G +++WDIG+P QLLT + L + ++PS + L+ CEDG F W + R K + + E+ P ++E D LA L+E K V +G I+ ++ + L K RK ++ A ++ Q++W ++ Y+ ++ V CGD +G IW+YD+ + + + R C +P KIL WP + E V K +IN V + YLVA+TD N+V IW I
Sbjct: 309 NIEPLHFLQCHSKNNSCEDFKTQLWACAFEP-----ILDSSSPKAVATCGGDSVCIIDCETGKVMKKYKVTGEEFFTLVWTTLTMIGKDEQKRKINVLAAGGKHGVVRIIHAKVSLCYGEIKAHKKAISIMCFSPKQDTFLFTGSYDKRIILWDIGVPDCDYNFRPSQLLT-----LDTTSVPLRMCLVPSCPDEFLVAACEDGCFAW---DIRLDKKQGRRSYEVELNFPIYKEERKDNDFHVIDSLAFLNEDIIASKSVMQGSIYLWSWEKTL---KTRKTKNVKKLDAVILAQMKWSSSETPYLVLSTSPERYCVFCGDEDGKIWIYDL--DSCKADLQRGKLCSVVKEPTKILSWP-----------ILFSPKEKVEKT-LINVVTVDPTMEYLVALTDINIVSIWKI 690
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q8BUI3|LRWD1_MOUSE (Leucine-rich repeat and WD repeat-containing protein 1 OS=Mus musculus OX=10090 GN=LRWD1 PE=2 SV=1) HSP 1 Score: 206.453 bits (524), Expect = 2.793e-54 Identity = 136/400 (34.00%), Postives = 208/400 (52.00%), Query Frame = 1
Query: 4534 DPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS-VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWT--TVEMAGGH--YINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDD--IQHPDF----EVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
+PLHF++CH+R+N+P D T++W CAFEP + TS VATCGGE VC+IDC+TG V+ ++K EEF++VAWT TV GH N+LAAAG +RLLH C + ++ H++ IA + F P + T LF+ +++WDIG+P+ QLLT L C L L V D L+ GCE G + W + R +P + +F + KV + DGLA ++E K +G I+ ++ Q + R Q+ + ++ +L+W T+ Y +++ V CGD EG++W+YD+ + E + P +IL WP+ + + V K +IN V ++ TYL A+TD+N+V IW
Sbjct: 273 EPLHFLQCHSRNNSPKDLETQLWACAFEPAREEGHSRATSQTVATCGGEAVCVIDCQTGLVLHKYKVPGEEFFSVAWTALTVVTQAGHKKRWNMLAAAGLRGMVRLLHVRAGFCCSVIRAHKKAIATLCFSPSHETHLFTASYDKRIILWDIGVPNQDYKFQASQLLT-LNCGSVPLR--LCPVATCPDDFLLAGCEGGCYCW---DVRLDQPQKQRVCEVNFIFSEDSKVSGQR---VDGLAFVNEDVVASKGSGQGTIYLWSWSQT---WAGR--GRQSVLPVVILVRLQWSPTNLAYFSLSTCPGKNLVLCGDEEGSVWIYDVEHLLKEPPQATTLQ-PPTQILKWPQPTALG-----------QPVTKT-MINTVVANAAFTYLTALTDSNIVSIW 645
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9UFC0|LRWD1_HUMAN (Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2) HSP 1 Score: 204.527 bits (519), Expect = 1.166e-53 Identity = 137/427 (32.08%), Postives = 209/427 (48.95%), Query Frame = 1
Query: 4483 PNPQCKGISVNGK-----TPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMA--GGH--YINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLT-------KLMCPRAHLNPVLNLVVMPSYDA-LITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPC---FDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWS 5703
P+ Q +G V G +PLHF++CH+++N+P D T++W CAFEP T+ VATCGGE VC+IDC+TG V+ ++K+ EEF++VAWT + + GH ++LAAAG +RLLH C ++ H++ IA + F P + T LF+ +++WDIG+P+ QLLT +CP V DA L+ GCE G W + R +P + + E E DGLA ++E K G I ++ Q + R Q+ + V+ +L+W T+ Y +++A + G V CGD EG +WLYD+S + + P +IL WP+ + V K ++N V ++ TYL A+TD+N+V IW
Sbjct: 252 PSAQVEGSPVAGSDGSQPAVKLEPLHFLQCHSKNNSPQDLETQLWACAFEPAWEEG--ATSQTVATCGGEAVCVIDCQTGIVLHKYKAPGEEFFSVAWTALMVVTQAGHKKRWSVLAAAGLRGLVRLLHVRAGFCCGVIRAHKKAIATLCFSPAHETHLFTASYDKRIILWDIGVPNQDYEFQASQLLTLDTTSIPLRLCP-----------VASCPDARLLAGCEGGCCCW---DVRLDQPQKRRVCEVEFVFSEGSEASGRRVDGLAFVNEDIVASKGSGLGTICLWSWRQT---WGGR--GSQSTVAVVVLARLQWSSTELAYFSLSACPDKGIVLCGDEEGNVWLYDVSNILKQPPLLPAALQAPTQILKWPQPWALG-----------QVVTKT-MVNTVVANASFTYLTALTDSNIVAIWG 645
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. UniProt/SwissProt
Match: sp|B0R160|LRWD1_DANRE (Leucine-rich repeat and WD repeat-containing protein 1 OS=Danio rerio OX=7955 GN=lrwd1 PE=1 SV=1) HSP 1 Score: 203.756 bits (517), Expect = 1.198e-52 Identity = 119/400 (29.75%), Postives = 211/400 (52.75%), Query Frame = 1
Query: 4537 PLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPY--LETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMA--GGHY--INILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVFVWLFP----EFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
PLH ++CH+R N+P D +T++W CAFEP ++ + +ATCGGE +C+I+C +G V+K++K E+F+++AW+TV M+ GG NILAA GK ++L+HP + + E + + I+ M F+PR PT LF+G + +WDIG + +++ ++KL+ P L+L ++PS L++GC++G++ + ++++ +I P ++ + DGL+ LS+ K +G I+ ++ + +RK + A ++ +L+W TD Y+++ G V CGD +G +W+Y ++ + EN + K ++L WP + + + P IN M YLVA+TD N+V +W
Sbjct: 380 PLHVLQCHSRQNDPDDFSTQLWACAFEPQQDDSIDISGGSQTIATCGGETLCVINCESGLVLKKYKVPGEDFFSLAWSTVLMSRTGGSARPCNILAAGGKRGCVKLIHPRVNLAFGEFRVSRRAISIMRFNPRKPTFLFTGTYDKKIFLWDIG---GLDQDYNFK-ISKLLTLETSSTP-LHLALLPSSPDTHLLSGCDEGLYCFDVQLSKNTLKRNEEIEIVFPIYKKNDKKNNYRTIDGLSFLSDDVVASKSHMQGSIYLWSWSATRASWNSRK----KEVPAVILAELQWSSTDIPYLSLGTCPGYGYVVCGDEQGRLWMYHITDTMMENFKSGK-TISATEVLQWPSPI-----------RAGKGALEGPSINSTAMDPGLHYLVALTDKNMVVVW 758
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. TrEMBL
Match: A0A0X3PNS6 (WD_REPEATS_REGION domain-containing protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR146077 PE=4 SV=1) HSP 1 Score: 600.127 bits (1546), Expect = 1.968e-176 Identity = 265/405 (65.43%), Postives = 319/405 (78.77%), Query Frame = 1
Query: 4495 CKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSD-KINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
C + G+ DYDPLHFIRCHARDN+PLDC+TKVWRCAFEPNP +P TT+VVATCGGECVCLIDCRTGKVMKRFK EEFYTVAWTTVEMA GH N+LAAAGKM++IRLLHPEQLVCYAEM+GH+ E+ACM FHP PT+LFSGD+ A +L+WDIGIPSAPEY+T +QLL +L+CPRA+LNPVLNL MP+YD L+ GCEDGVF W +FRK K D + P E+KVPT +EPCFDGLARLSE+ F+VKCVEEGE++ I+F Q+L K R + + A+++GQLRWQ T+EIYINVT++ LG+V CGDNEGTIWLYD+ V +KFK KP KIL+WPECSV + D ++ + + KNP+IN ++SSDG YLVAVTDNNLVCIW+
Sbjct: 1652 CPSLLQLGEIVDYDPLHFIRCHARDNDPLDCSTKVWRCAFEPNPLDPKNSTTTVVATCGGECVCLIDCRTGKVMKRFKHIGEEFYTVAWTTVEMATGHQTNLLAAAGKMREIRLLHPEQLVCYAEMRGHKDEVACMLFHPYRPTILFSGDSKAFILVWDIGIPSAPEYSTKHQLLMRLVCPRANLNPVLNLAFMPNYDTLLAGCEDGVFAWTLQDFRKEKAGDERPPTMEIKVPTRREPCFDGLARLSENLFVVKCVEEGELYIIDFSQLLLR-KKRTTAAKKVVPAEILGQLRWQTTEEIYINVTSRPGLGAVVCGDNEGTIWLYDLQANVRSQKDGKKFKLKPVKILEWPECSVGGNREDDVQLKESITSGFKNPVINATDISSDGAYLVAVTDNNLVCIWNF 2055 HSP 2 Score: 226.098 bits (575), Expect = 2.328e-55 Identity = 166/483 (34.37%), Postives = 249/483 (51.55%), Query Frame = 1
Query: 1774 KRDL--QLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFEL----QIRDEIPRLQAMLDGNPSEVE--------------QAMEYMRETSAVNGR-----------------------FLPTQRTRHQP-LSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVT-------VPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
+R+L +L SEE A++ AA + ++ IKPKSDCT E Q D R +++ PS Q ++ +RE +A+ GR ++P R+ P L+PY+VA NEAA +L LLT R+ L + A+KVVR SG F H D+ LY + + ELDLS A ++L D LE L S + P E T + ++N+ CE +NI++E IY +GTD LKKVRIL+LA+CSFT L+P+ +N+C NLVELNL NN + LPRCL+LP L +LN++ N + PL+EQF +L S+ELD + L ++L++ CP L+ IN ++F S++ A+ + +++ S+WE+DL ++KK + + +V+ETLVL + V +E F + K ++ARR+AE FL
Sbjct: 700 RRELAYKLAASEEEALRLAAISVLSDIPSMDIKPKSDCTNIERACWEQAVDLSARADSLIAAEPSSAAAGPNAVANLLVNDAQRVDSVREMAALYGRTVLSGTAAAVAAQQQQQQQLLNPYIPPPRSPSLPVLTPYEVACNEAAAYLAAGQPALLTRRRDLVELARKVVRNSGFQFPHTPNMDRGSGGPGGYRLYCADQLMELDLSAAEQLLLDPLERTELEDNPQS-YSPASESTEGECP----------------------SLNLSCEEHNNIIDEVAIYAASGTDSLKKVRILNLADCSFTGLIPLHLNFCINLVELNLSNNCLHALPRCLYLPKLRRLNIRGNPMLARFCHLEGPPLVEQFARLVSLELDPDLKDLLKPQALAYLCPHLSSINGEEFHEEASEDTIKAAQSAKQELAALIHSKWEDDLVGFYKKSIPHRDLIRVLETLVLHAVNQSVAVDEPFSHCKAILARRIAEEFL 1159 HSP 3 Score: 158.688 bits (400), Expect = 9.414e-35 Identity = 143/506 (28.26%), Postives = 232/506 (45.85%), Query Frame = 1
Query: 142 ETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVIS-------------NTTNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENK------LAVTDNE-EQIQG-----EQFLISEYPTT--TPNVFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISG-INEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPIN----DDTSQQEPVDNNEE-----EYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQN-------SEADDPAALWGPSELSKEEYAAIREQSRSVA-----AGFENNNDLPAVQPYSEALGSLTAYQELVGLVERYK--SKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLY 1506
E G+ LVK+ +D+NN + S YA+++ ++M GE TL IDE+GK LV + S + + +N ++ + + S++ +G Q+ +++ S V + + E +A T NE E I EQ+ I+E + V + D+ G + +K G +GE +++EL G Y + G I+ D T + + ++ + Q + G ++ + Q E N E ++ +TE I DG+ Q V L +LD+K G G+ ++L + +YV GP E GEPI T ++ D+E ++ E Q+ SEA AA W P LS+E YA++R ++ ++ + E + +PY LG AYQE+V LV+ YK + E MLR ++K++ + P AR LT E NE AAQ+CR+ P LLFHKR L+
Sbjct: 42 ENGQELVKLMFMDENN-ETSGYALVSTEDAKKIMTGEATLQNVIDEEGKQVLTLVPVEQDLSAAEDGVNPTMTADGAGGAPAAATAAGADDFAASESTAVG-----QKAPESVPAPKSPVDGNSTTTALVKTEGTHVAVADVAATSNEAEAIAATDENVEQYTITEQTAILDGQTIRMVSLVDTAGNVLDQKHGQVGEQVVIELHGQAFVYEMRGPIDGDEPITSTLLVSAAEAEEEAEGASS----QQTSAGDGGAVHAQWTAEGQQSETAAENSEVPAGQQFTLTEAVAIVDGKTMQTVILEDDKGNVLDQKQGHAGEHAIIELNGHSLDYVFLGPSETGEPITTVLVV--AADEEGQDGEMQDGGSLVSESEAGMTAANWCPQGLSQELYASLRLKAEAIVNERLQSRIELSYPHSRPEPYHRKLGPYAAYQEMVELVKTYKAGASQGETLERYEMLRTYAKIFRSSGPQARPLTVFEMVVNEVAAQLCRFKPGLLFHKRELF 535 HSP 4 Score: 72.7886 bits (177), Expect = 1.313e-8 Identity = 37/69 (53.62%), Postives = 48/69 (69.57%), Query Frame = 1
Query: 3247 DEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPVXXXXXXXXXXSSYLVSASNKKSAIDGTTG 3453
DEPLD+L+N++G AL+ GKTV+YSV+RTAARQP G+LIPV SS SA N ++ DG +G
Sbjct: 1281 DEPLDKLSNIIGMALQHGKTVIYSVIRTAARQPNGELIPV---------GSSLSGSAVNGLASADGKSG 1340
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. TrEMBL
Match: W6UV15 (Leucine-rich repeat and WD repeat-containing protein OS=Echinococcus granulosus OX=6210 GN=EGR_02969 PE=4 SV=1) HSP 1 Score: 592.038 bits (1525), Expect = 2.219e-174 Identity = 266/401 (66.33%), Postives = 319/401 (79.55%), Query Frame = 1
Query: 4516 GKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKE-VNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVN---KNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
G+ DYDPLHFIRCHARDN+PLDC+TKVWRCAFEPNP +P TTSVVATCGGECVCLIDC+TGKV+KRFK EEFY VAWTTVEMA GH N+LAAAGK+K+IRLLHPEQLVCYAEMKGH +EIACM FHP PT+LFSGD+ A V +WD+G+PSAPEY T + LL +L+CPR HLNPVLNLV MP+YD L+ GCEDGVF W+ +FRK + D + P E+K+PT++EPCFDGLARLSE+ +VKCVEEGEI+ +F Q+L K R + + A+V+GQLRWQ TDEIYINVTA+ LG+V CGDNEGTIW+YD+ + VNE N T KFK KP KIL+WPECSV + D Q E++N KNP++N ++SSDG++LVAVTDNNLVCIW+
Sbjct: 1536 GEVVDYDPLHFIRCHARDNDPLDCSTKVWRCAFEPNPTDPR-STTSVVATCGGECVCLIDCQTGKVLKRFKHVGEEFYAVAWTTVEMASGHPTNLLAAAGKLKEIRLLHPEQLVCYAEMKGHREEIACMVFHPTKPTILFSGDSKACVCVWDVGVPSAPEYRTKHHLLMRLICPRPHLNPVLNLVFMPNYDTLLAGCEDGVFAWIIQDFRKQRFADDRVPTMEIKIPTNREPCFDGLARLSENLVVVKCVEEGEIYVFDFAQLLLSRK-RAASSKKMVTAEVLGQLRWQTTDEIYINVTARPGLGAVVCGDNEGTIWVYDLQEHVVNEENST-KFKVKPVKILEWPECSVGGNREEDP--QVKESINSGFKNPVVNATDISSDGSFLVAVTDNNLVCIWNF 1931 HSP 2 Score: 174.096 bits (440), Expect = 1.858e-39 Identity = 152/502 (30.28%), Postives = 226/502 (45.02%), Query Frame = 1
Query: 142 ETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKP----------QFMLVEANES------------ESDSINTLNKVISNT--TNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPN--VFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNE----------EEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVA-AGFENNNDL----PAVQPYSEALGSLTAYQELVGLVERYK--SKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAV 1518
E G LVK+ +D+N+ + S YA+++ R+M GE TL IDEDGK QF L EA S D++ + V++ T + K DE +++D ++V D++ K D + + T + EQF I+E N + V + DS G I +K G G ++++L G +Y I G E G + + E QT+ L P + + SQ + + + ++Y +TE + DG+ Q V L I+D+K G G+ V ++L ++ +YV GP ENGEP+ T ++ + DD +E SEA AA W P LS + Y IR S ++ N +L A +PY LGS AYQE+V L + Y + E LR H+K+Y P AR LT E NE A+Q+CR+ P LLFHKR LY A+
Sbjct: 46 ENGNELVKLLFMDEND-ESSGYALVSPEDAKRIMNGEATLQNVIDEDGKQVLTLVPVEQDQFGLQEAAGSGEGGKSEPAPPPSEDNVKSSEDVVAPPFETETSTDKKTDEEATEAISKED--SVVPDIAPTKE------DVEVASAGPATTSAGAENAEQFTITEQSALLDNQPIQMVSLLDSAGNVIDQKHGQTGAQVVMQLHGQAFAYEIRGPTETGEPLTSTLLLSV----------ESAEEQTVSQLVNAPESSENSQVQWLASESKQAESDIPAGQQYTLTEATATVDGKSVQTVVLEDDKGNIMDQKQGNIGEHVIIELNGQSLDYVFLGPSENGEPVQTVLVVTQ-DDGSGDE-----SEAGLTAANWCPVGLSHDLYTTIRRHSEAIVHERLSNRPELSFPNAASEPYQRKLGSYAAYQEMVELAKTYAVGASQGETLERYETLRGHAKIYR-CGPQARPLTVNEMVINEVASQLCRFKPGLLFHKRELYQLAL 521 HSP 3 Score: 147.902 bits (372), Expect = 1.851e-31 Identity = 101/247 (40.89%), Postives = 145/247 (58.70%), Query Frame = 1
Query: 2389 IYRPREFRD-SELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVR------------ILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVT-------VPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
+ R RE + + L ++++ CE EHNIL++ IY TGTD LKK + L +CSFT +MPI +N C NLVELNL NN + LPRCL LP L +LNL KN + PL+EQFP+L SVELD ++ L +SL++ CP L IN ++F +++ T A+ + ++V S+WE+DL +FKK V + VIETLVL + + +E F + K ++AR++AE FL
Sbjct: 806 LTRRRELAELAHKLMSLDLSCE-EHNILDDIAIYTVTGTDTLKKTTDYFPMYISKFNFLPSLPDCSFTGIMPIHLNQCVNLVELNLSNNCLHGLPRCLHLPKLKRLNLSKNPLLVRFARENGPPLIEQFPRLISVELDPELKEMLKPQSLAYLCPLLNSINGEEFNVEATEDTIKTAQAAKQELAALVHSKWEDDLVEFFKKSVPHRDLICVIETLVLHAVNQSLTVDEPFKHCKAVLARQIAEEFL 1051 HSP 4 Score: 67.0106 bits (162), Expect = 7.251e-7 Identity = 29/41 (70.73%), Postives = 36/41 (87.80%), Query Frame = 1
Query: 3238 LLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLI 3360
LL DEPLDRL+ ++G A++ GKTVVYSV+R+AARQP GDLI
Sbjct: 1158 LLPDEPLDRLSGIIGTAMQHGKTVVYSVIRSAARQPNGDLI 1198
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. TrEMBL
Match: A0A068WGD1 (DEAD box ATP dependent RNA helicase OS=Echinococcus granulosus OX=6210 GN=EgrG_001027400 PE=4 SV=1) HSP 1 Score: 592.038 bits (1525), Expect = 2.935e-174 Identity = 266/401 (66.33%), Postives = 319/401 (79.55%), Query Frame = 1
Query: 4516 GKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKE-VNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVN---KNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
G+ DYDPLHFIRCHARDN+PLDC+TKVWRCAFEPNP +P TTSVVATCGGECVCLIDC+TGKV+KRFK EEFY VAWTTVEMA GH N+LAAAGK+K+IRLLHPEQLVCYAEMKGH +EIACM FHP PT+LFSGD+ A V +WD+G+PSAPEY T + LL +L+CPR HLNPVLNLV MP+YD L+ GCEDGVF W+ +FRK + D + P E+K+PT++EPCFDGLARLSE+ +VKCVEEGEI+ +F Q+L K R + + A+V+GQLRWQ TDEIYINVTA+ LG+V CGDNEGTIW+YD+ + VNE N T KFK KP KIL+WPECSV + D Q E++N KNP++N ++SSDG++LVAVTDNNLVCIW+
Sbjct: 1552 GEVVDYDPLHFIRCHARDNDPLDCSTKVWRCAFEPNPTDPR-STTSVVATCGGECVCLIDCQTGKVLKRFKHVGEEFYAVAWTTVEMASGHPTNLLAAAGKLKEIRLLHPEQLVCYAEMKGHREEIACMVFHPTKPTILFSGDSKACVCVWDVGVPSAPEYRTKHHLLMRLICPRPHLNPVLNLVFMPNYDTLLAGCEDGVFAWIIQDFRKQRFADDRVPTMEIKIPTNREPCFDGLARLSENLVVVKCVEEGEIYVFDFAQLLLSRK-RAASSKKMVTAEVLGQLRWQTTDEIYINVTARPGLGAVVCGDNEGTIWVYDLQEHVVNEENST-KFKVKPVKILEWPECSVGGNREEDP--QVKESINSGFKNPVVNATDISSDGSFLVAVTDNNLVCIWNF 1947 HSP 2 Score: 217.624 bits (553), Expect = 8.248e-53 Identity = 174/479 (36.33%), Postives = 244/479 (50.94%), Query Frame = 1
Query: 1774 KRDL--QLNNSEETAIKNAAERLQEEL-YQYPIKPKSDCTAFELQIRDEIPRLQAMLD------GNPSEVEQAM-------EYMRETSAVNGRFLPTQRTRHQP------------------------LSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVT-------VPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
KRDL +L+ SE A++ AA +L +KPKSDCT E D L A+ +P V + + +RE++A+ GR P Q T P L+PY+ A NEAA +L LLT R+ LA+ A+KVVR GC F H D+ ++ + V ELDLS A ++L D LE L + S + D +L+ ++++ CE EHNIL++ IY TGTD LKKVRIL L +CSFT +MPI +N C NLVELNL NN + LPRCL LP L +LNL KN + PL+EQFP+L SVELD ++ L +SL++ CP L IN ++F +++ T A+ + ++V S+WE+DL +FKK V + VIETLVL + + +E F + K ++AR++AE FL
Sbjct: 627 KRDLTYKLSASEMEALRLAAINALTDLPTTLEVKPKSDCTNIERASWDRATELAALRSESAIDTTDPHAVASLLVNDTTRVDSVRESAALYGR-TPLQSTSSGPSANVISPPYPVASQLATAARSSPLLTPYETACNEAAAYLAAGQPALLTRRRELAELARKVVRNCGCQFTHAPSLDRG--------YFSVDQVMELDLSAAEQLLHDPLERLDLNDSLESDSL---------------------------DDKLM-SLDLSCE-EHNILDDIAIYTVTGTDTLKKVRILSLPDCSFTGIMPIHLNQCVNLVELNLSNNCLHGLPRCLHLPKLKRLNLSKNPLLVRFARENGPPLIEQFPRLISVELDPELKEMLKPQSLAYLCPLLNSINGEEFNVEATEDTIKTAQAAKQELAALVHSKWEDDLVEFFKKSVPHRDLICVIETLVLHAVNQSLTVDEPFKHCKAVLARQIAEEFL 1067 HSP 3 Score: 173.711 bits (439), Expect = 2.347e-39 Identity = 152/502 (30.28%), Postives = 226/502 (45.02%), Query Frame = 1
Query: 142 ETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKP----------QFMLVEANES------------ESDSINTLNKVISNT--TNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPN--VFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNE----------EEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVA-AGFENNNDL----PAVQPYSEALGSLTAYQELVGLVERYK--SKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAV 1518
E G LVK+ +D+N+ + S YA+++ R+M GE TL IDEDGK QF L EA S D++ + V++ T + K DE +++D ++V D++ K D + + T + EQF I+E N + V + DS G I +K G G ++++L G +Y I G E G + + E QT+ L P + + SQ + + + ++Y +TE + DG+ Q V L I+D+K G G+ V ++L ++ +YV GP ENGEP+ T ++ + DD +E SEA AA W P LS + Y IR S ++ N +L A +PY LGS AYQE+V L + Y + E LR H+K+Y P AR LT E NE A+Q+CR+ P LLFHKR LY A+
Sbjct: 16 ENGNELVKLLFMDEND-ESSGYALVSPEDAKRIMNGEATLQNVIDEDGKQVLTLVPVEQDQFGLQEAAGSGEGGKSEPAPPPSEDNVKSSEDVVAPPFETETSTDKKTDEEATEAISKED--SVVPDIAPTKE------DVEVASAGPATTSAGAENAEQFTITEQSALLDNQPIQMVSLLDSAGNVIDQKHGQTGAQVVMQLHGQAFAYEIRGPTETGEPLTSTLLLSV----------ESAEEQTVSQLVNAPESSENSQVQWLASESKQAESDIPAGQQYTLTEATATVDGKSVQTVVLEDDKGNIMDQKQGNIGEHVIIELNGQSLDYVFLGPSENGEPVQTVLVVTQ-DDGSGDE-----SEAGLTAANWCPVGLSHDLYTTIRRHSEAIVHERLSNRPELSFPNAASEPYQRKLGSYAAYQEMVELAKTYAVGASQGETLERYETLRGHAKIY-RCGPQARPLTVNEMVINEVASQLCRFKPGLLFHKRELYQLAL 491 HSP 4 Score: 66.6254 bits (161), Expect = 7.446e-7 Identity = 29/41 (70.73%), Postives = 36/41 (87.80%), Query Frame = 1
Query: 3238 LLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLI 3360
LL DEPLDRL+ ++G A++ GKTVVYSV+R+AARQP GDLI
Sbjct: 1174 LLPDEPLDRLSGIIGTAMQHGKTVVYSVIRSAARQPNGDLI 1214
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. TrEMBL
Match: A0A4E0RDR1 (Leucine-rich repeat and WD repeat-containing protein 1 OS=Fasciola hepatica OX=6192 GN=D915_004183 PE=4 SV=1) HSP 1 Score: 594.349 bits (1531), Expect = 6.124e-174 Identity = 261/407 (64.13%), Postives = 323/407 (79.36%), Query Frame = 1
Query: 4483 PNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSD-KINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
P P + +S G DYDPLHFIRCHARDN+PLDC TKVWRCAFEP+ N+P+ ET++VVATCGGECVCLIDCR+G+VMKRFK EEFYT+AWTTVEM+ GH N+LAAAGK+++IRLLHPEQLVCYAEM+GH+ +IACM FHP PTVLFSGD+ A +L+WDIGIPSAPEY T +QLL +L+CPRA+LNPVLNLV +P +DAL+ GCEDGVF W P+FRK K ++ + D E+K+PT EPCFDGLA+L+E +VKCVEEGEI+ +F Q+LQ K R + + ++ GQLRWQ TDEIYINVTA+ L +V CGDNEGTIWLYD+ K+V E+ +R+FK KP KIL+WPECSV T D D ++ ++ + KNP++N ++S DG YLVAVTDNNLVCIW
Sbjct: 1727 PKPGARSLSELGSVVDYDPLHFIRCHARDNDPLDCETKVWRCAFEPSVNDPHNETSTVVATCGGECVCLIDCRSGRVMKRFKHFGEEFYTLAWTTVEMSTGHKTNLLAAAGKLREIRLLHPEQLVCYAEMRGHKDDIACMIFHPTKPTVLFSGDSKACILVWDIGIPSAPEYRTRHQLLMRLVCPRANLNPVLNLVFLPKFDALVAGCEDGVFSWTLPDFRKEKLNEERTADLELKIPTRCEPCFDGLAKLTEQLIVVKCVEEGEIYVFDFAQVLQRAK-RLTSGKKHVTVELRGQLRWQTTDEIYINVTARPGLNAVVCGDNEGTIWLYDLQKQVTED--SRRFKSKPVKILEWPECSVGGTKDEDSQLKENITSGFKNPVVNTTDISHDGQYLVAVTDNNLVCIW 2130 HSP 2 Score: 221.861 bits (564), Expect = 5.339e-54 Identity = 172/478 (35.98%), Postives = 244/478 (51.05%), Query Frame = 1
Query: 1774 KRDL--QLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQ--------AMLDGNPSEV---------EQAMEYMRETSAV-----------NGRFLPTQRTRHQP-LSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLE--DGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGN---VNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXX----------XXAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
KRD +L +E ++K AA L EL Y +KPK DCT EL ++ +L A LD + E + +RE++A+ NG + R+ P L PY+VA NEAA +L LLT R+ LA+ AKKVVR SGC F T DK Y + +PELDLS A +L+D L+ D P + S P E + N + + CE +N++++ IY TGTD LKKVRIL+L++C FT L+P+ +N C NL+ELNL N++ PRCL LP L +LNL+ V PL+EQFP+L S+ELD K+A L ++SL++ CP L IN + F SDE + + I ++ S+WE+D++ ++KKG+ K +A +VIETLVL +R +F + ++ARRVAE FL
Sbjct: 690 KRDAMNKLTIQQEESLKTAALDLLYELPHYDLKPKVDCTNIELACWEQARQLSSETLSLDTAALDSAHASHASFNALLCNEARLNGVRESAALYGRQAGFMQPPNGTGVGIARSPTVPVLIPYEVACNEAAAYLAAAMPNLLTHRRDLAELAKKVVRNSGCLFT-TTAADKIAATGGGYRFYCTDQLPELDLSAADHLLTDPLDRSDSPDSGCCVS-------------------------PTETETDGVTVNFQTLALSCEECNNVVDDVTIYTTTGTDSLKKVRILNLSDCGFTGLIPMYVNQCSNLIELNLSGNALYGFPRCLHLPKLKRLNLRGNPRLLRPNPSTGTVEPPLVEQFPRLVSLELDPKLAELLCRQSLAYLCPYLKLINGEDFTEEPSDETMKIIQATKHQISGLIYSKWEDDIAGFYKKGLPKRDAIRVIETLVLHSVKRTDDLARQFSHCTSILARRVAEDFL 1141 HSP 3 Score: 190.66 bits (483), Expect = 1.728e-44 Identity = 149/510 (29.22%), Postives = 243/510 (47.65%), Query Frame = 1
Query: 142 ETGETLVKVNIVDDNNPDEST-YAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVISNTTNLHSISKAD--------------EMGILIDNQQDIKNIVGD---VSHVKNRESLELDQQFENKLAVTDNEEQI--QGEQFLISEYPTTTPN--VFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTN-----EVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNE-----EEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEV-------EESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGF--ENNNDLPAV--QPYSEALGSLTAYQELVGLVERY--KSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRT 1536
E+G+ LVK+ +D+N DE+T YA++ +++ GE L +D++GK L + D +N + TT S+S AD G +D ++ + D V N S + + E+ ++ + I EQF++SE N + V + DS G+ + +K G+ GE ++LE+ SY + G ++ G + + + D T+ E +PR P DDTS D +E +++ +TE + +G P Q V L ++ +LD+K G G+ V ++++ + EYV GP E+GEPI TT ++ + E +H+ SEA AA W PS L E Y+ + Q+ ++ A ++ + P +PY LG L YQ +V +V Y + E +LR ++K+Y P+ P++R LT E A NEAAAQ+CRY P LLFHKR L+ A V+++
Sbjct: 19 ESGQVLVKLVFMDEN--DEATGYALVAPEDAKKILSGEAALQNVVDDEGKQVLTLAPVVPEDQDDLNQ-HPEDDATTCASSVSVADVAEPPKATSVPDESNSGNEVDVSPAVQPMKADEKTTGIVTNSTSEDGNAGVESAPVENESLQTIPENVEQFVLSEQTAMVNNKPIQVVTLMDSQGQVLDQKQGETGEQVVLEIFRQMFSYELQGPSDTGEPITSTLLVSAGNADDTDTAVPEERTSEVPRTATAP----NWTDDTSASRGYDQSEVTPAGQQFTLTEAMALVNGDPMQTVILTDENGNVLDQKQGHTGEHVIIEMSGNSLEYVFLGPTESGEPITTTLVVTTDPEAADVAQADAVESDQHECSEAVGTAADWCPSGLPPEFYSVLCRQAEAIVALRIPQSADGTPTYRPEPYHRKLGPLATYQSMVEVVNSYLLGASRGETLAGYEVLRNYAKIYRPSGPHSRALTKYELALNEAAAQICRYHPGLLFHKRELFHLAKETVEQS 521 HSP 4 Score: 69.707 bits (169), Expect = 1.012e-7 Identity = 33/43 (76.74%), Postives = 37/43 (86.05%), Query Frame = 1
Query: 3238 LLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPV 3366
LL DE DRL NVVGQALR GKTVVY+V+RTA+RQP G+LIPV
Sbjct: 1234 LLPDESPDRLVNVVGQALRHGKTVVYAVIRTASRQPNGELIPV 1276
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. TrEMBL
Match: A0A504Z8L4 (Leucine rich repeat and WD repeat containing (Fragment) OS=Fasciola gigantica OX=46835 GN=FGIG_10467 PE=4 SV=1) HSP 1 Score: 592.423 bits (1526), Expect = 8.324e-174 Identity = 261/407 (64.13%), Postives = 323/407 (79.36%), Query Frame = 1
Query: 4483 PNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSD-KINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
P P + +S G DYDPLHFIRCHARDN+PLDC TKVWRCAFEP+ N+P+ ET++VVATCGGECVCLIDCR+G+VMKRFK EEFYT+AWTTVEM+ GH N+LAAAGK+++IRLLHPEQLVCYAEM+GH+ +IACM FHP PTVLFSGD+ A +L+WDIGIPSAPEY T +QLL +L+CPRA+LNPVLNLV +P +DAL+ GCEDGVF W P+FRK K ++ + D E+K+PT EPCFDGLA+L+E +VKCVEEGEI+ +F Q+LQ K R + + ++ GQLRWQ TDEIYINVTA+ L +V CGDNEGTIWLYD+ K+V E+ +R+FK KP KIL+WPECSV T D D ++ ++ + KNP++N ++S DG YLVAVTDNNLVCIW
Sbjct: 1644 PKPGARSLSELGSVVDYDPLHFIRCHARDNDPLDCETKVWRCAFEPSVNDPHNETSTVVATCGGECVCLIDCRSGRVMKRFKHFGEEFYTLAWTTVEMSTGHKTNLLAAAGKLREIRLLHPEQLVCYAEMRGHKDDIACMIFHPTKPTVLFSGDSKACILVWDIGIPSAPEYRTRHQLLMRLVCPRANLNPVLNLVFLPKFDALVAGCEDGVFSWNLPDFRKEKLNEERTADLELKIPTRCEPCFDGLAKLTEQLIVVKCVEEGEIYVFDFAQVLQRAK-RLTSGKKHVTVELRGQLRWQTTDEIYINVTARPGLNAVVCGDNEGTIWLYDLQKQVTED--SRRFKAKPVKILEWPECSVGGTKDEDSQLKENITSGFKNPVVNTTDISHDGQYLVAVTDNNLVCIW 2047 HSP 2 Score: 221.861 bits (564), Expect = 4.846e-54 Identity = 172/478 (35.98%), Postives = 244/478 (51.05%), Query Frame = 1
Query: 1774 KRDL--QLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQ--------AMLDGNPSEV---------EQAMEYMRETSAV-----------NGRFLPTQRTRHQP-LSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLE--DGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGN---VNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXX----------XXAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
KRD +L +E ++K AA L EL Y +KPK DCT EL ++ +L A LD + E + +RE++A+ NG + R+ P L PY+VA NEAA +L LLT R+ LA+ AKKVVR SGC F T DK Y + +PELDLS A +L+D L+ D P + S P E + N + + CE +N++++ IY TGTD LKKVRIL+L++C FT L+P+ +N C NL+ELNL N++ PRCL LP L +LNL+ V PL+EQFP+L S+ELD K+A L ++SL++ CP L IN + F SDE + + I ++ S+WE+D++ ++KKG+ K +A +VIETLVL +R +F + ++ARRVAE FL
Sbjct: 607 KRDAMNKLTIQQEESLKTAALDLLYELPHYDLKPKVDCTNIELACWEQARQLSSETLSLDTAALDSAHASHASLNALLCNEARLNGVRESAALYGRQAGFMQPPNGTGVGIARSPTVPVLIPYEVACNEAAAYLAAAMPNLLTHRRDLAELAKKVVRNSGCLFT-TTAADKIAATGGGYRFYCTDQLPELDLSAADHLLTDPLDRSDSPDSGCCVS-------------------------PTETETDGVTVNFQTLALSCEECNNVVDDVTIYTTTGTDSLKKVRILNLSDCGFTGLIPMYVNQCSNLIELNLSGNALYGFPRCLHLPKLKRLNLRGNPRLLRPNPSTGTVEPPLVEQFPRLVSLELDPKLAELLCRQSLAYLCPYLKLINGEDFTEVPSDETMKIIQATKHQISGLIYSKWEDDIAGFYKKGLPKRDAIRVIETLVLHSVKRTDDLARQFSHCTSILARRVAEDFL 1058 HSP 3 Score: 175.637 bits (444), Expect = 7.136e-40 Identity = 116/356 (32.58%), Postives = 182/356 (51.12%), Query Frame = 1
Query: 544 EQFLISEYPTTTPN--VFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTN-----EVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNE-----EEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLIN-------RGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGF--ENNNDLPAV--QPYSEALGSLTAYQELVGLVERY--KSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRT 1536
EQF++SE N + V + DS G+ + +K G+ GE ++LE+ SY + G ++ G + + + D T+ E +PR P DDTS D +E +++ +TE + +G+P Q V L ++ +LD+K G G+ V ++++ + EYV GP E+GEPI TT ++ D VE +H+ SEA AA W PS L E Y+ + Q+ ++ A ++ + P +PY LG L YQ +V +V Y + E +LR ++K+Y P+ P++R LT E A NEAAAQ+CRY P LLFHKR L+ A V+++
Sbjct: 87 EQFVLSEQTAMVNNKPIQVVTLMDSQGQVLDQKQGETGEQVVLEIFRQMFSYELQGPSDTGEPITSTLLVSAGNADDTDTAVPEERTSEVPRTATAP----NWTDDTSASRGYDQSEVTPAGQQFTLTEAMALVNGEPMQTVILTDENGNVLDQKQGHTGEHVIIEMSGNSLEYVFLGPTESGEPITTTLVVTTDPDAADVAQADAVESDQHECSEAVGTAADWCPSGLPPEFYSVLCRQAEAIVALRIPQSADGTPTYRPEPYHRKLGPLATYQSMVEVVNSYLLGASRGETLASYEVLRNYAKIYRPSGPHSRALTKYELALNEAAAQICRYHPGLLFHKRELFHLAKETVEQS 438 HSP 4 Score: 71.633 bits (174), Expect = 2.426e-8 Identity = 40/138 (28.99%), Postives = 74/138 (53.62%), Query Frame = 1
Query: 814 LEQGPINDDTSQQEPVDNNEEEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAG 1227
+E P+ +++ Q P N E++V++EQ+ + + +P Q VTL +LD+K G G+ V L++ + F Y +QGP + GEPI +T L++ G+ D+ + + + ++ P P+ + +QS AG
Sbjct: 69 VESAPVENESLQTIP--ENVEQFVLSEQTAMVNNKPIQVVTLMDSQGQVLDQKQGETGEQVVLEIFRQMFSYELQGPSDTGEPITSTLLVSAGNADDTDTAVPEERTSEVPRTATAPNWTDDTSASRGYDQSEVTPAG 204 HSP 5 Score: 69.707 bits (169), Expect = 1.057e-7 Identity = 33/43 (76.74%), Postives = 37/43 (86.05%), Query Frame = 1
Query: 3238 LLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPV 3366
LL DE DRL NVVGQALR GKTVVY+V+RTA+RQP G+LIPV
Sbjct: 1151 LLPDESPDRLVNVVGQALRHGKTVVYAVIRTASRQPNGELIPV 1193
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Cavefish
Match: lrwd1 (leucine rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:103025579]) HSP 1 Score: 208.379 bits (529), Expect = 4.315e-55 Identity = 126/399 (31.58%), Postives = 209/399 (52.38%), Query Frame = 1
Query: 4537 PLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLET-TSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMA--GG--HYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSY--DALITGCEDGVF---VWLFPEFRKHKPD-DIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
PLH ++CH++ N+P D +T++W CAFEP NN VATCGGE VC+IDC +G V+K++K EEFY++AWTT+ M+ GG +ILAA GK ++L+HP + Y E + + I+ + F P + + LF+G ++MWDIG + H++ ++L+ P L+L ++PS LI GC+ G++ + L +K + +I P ++ K +++ DGL+ L++ K +G I+ ++ +K +K + A ++ +L+W TD Y+++ G + CGD G +W Y ++ + N + K ++L+WP + V K P IN V M D YLVA++D N+V +W
Sbjct: 389 PLHVLQCHSKQNSPDDFSTQLWACAFEPVQNNGDATGWQQTVATCGGESVCVIDCESGHVLKKYKVPGEEFYSLAWTTLLMSREGGCARSCSILAAGGKRGIVKLIHPRVSMAYGEFRASRRAISALRFSPSHTSFLFTGAYDNKIVMWDIG---GLDRDYHFK-TSQLLVLETGSTP-LHLCLLPSSPNTHLIAGCDSGLYSFDIQLSKNTQKRSEEMEIVFPVYKKKDKSNEYRTIDGLSFLTDDIVASKSHMQGSIYLWSWSGTRDLWKGKK----KEVPAVILAELQWSSTDIPYLSLNTCPGFGYIVCGDENGRLWTYHITDLMKANFKSGKV-IPSTEVLEWP----------SPVRPGVGPV-KGPSINSVAMDPDLHYLVALSDKNMVVVW 766
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Cavefish
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:103041188]) HSP 1 Score: 54.299 bits (129), Expect = 9.058e-7 Identity = 35/112 (31.25%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + + H +LA AG IR+++ + C GH I + FHPR P +L S + +W+I
Sbjct: 112 VFATVGSNRVTLYECHSHGEIRLLQSYVDADADENFYTCAWT-YDTSTSH--PLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 220
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Cavefish
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:103041188]) HSP 1 Score: 53.9138 bits (128), Expect = 1.193e-6 Identity = 35/112 (31.25%), Postives = 53/112 (47.32%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + + H +LA AG IR+++ + C GH I + FHPR P +L S + +W+I
Sbjct: 112 VFATVGSNRVTLYECHSHGEIRLLQSYVDADADENFYTCAWT-YDTSTSH--PLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 220
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Sea Lamprey
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:550463]) HSP 1 Score: 53.9138 bits (128), Expect = 1.569e-7 Identity = 35/112 (31.25%), Postives = 52/112 (46.43%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +L AG IR+++P + C GH I + FHPR P +L S + +W+I
Sbjct: 109 VFATVGSNRVTLYECHSQGEVRLMQSYVDVEADENFYTCAWT-YDRNTSH--PLLGIAGSRGIIRIINPITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 217
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Yeast
Match: TAF5 (Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000000402]) HSP 1 Score: 51.2174 bits (121), Expect = 1.755e-6 Identity = 46/178 (25.84%), Postives = 75/178 (42.13%), Query Frame = 1
Query: 4597 VWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVF-VW 5127
V+ +F +P+N YL + S T V L T + +K + V+++ + GHY A A + RL + + GH ++ C++FHP +F+G + T MWD+ + +L H PV+++ V P L TG EDG+ VW
Sbjct: 528 VYSTSF--SPDNKYLLSGSEDKT-----VRLWSMDTHTALVSYKGHNHPVWDVSFSPL----GHY---FATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPN-GCYVFTGSSDKTCRMWDVSTGDS----------VRLFL--GHTAPVISIAVCPDGRWLSTGSEDGIINVW 678
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Nematostella
Match: EDO47466 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM96]) HSP 1 Score: 179.874 bits (455), Expect = 5.426e-47 Identity = 122/395 (30.89%), Postives = 191/395 (48.35%), Query Frame = 1
Query: 4531 YDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEM---AGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEV-NENNHTRKFKC-KPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
++ H ++ H+ +NNP D T+VW C FEP+ NNP +TTS+ ATCGG+ VC IDC TG+V+K++K E FY +AW+TV N+LAA G + I+++ P QLVC ++ G + + + FHP T L A T+ +W+IG+PS Y T +LL L V P ++ C+DG ++W + D + P ++ P + D + LS+S K V+EG I + H ++ +V V W+ T+ ++ + + + GD++G +WLYDM + +RK++ + +IL P NDS K+ C S D Y+VAV D N+VC+W
Sbjct: 264 FEVSHLLQTHSLNNNPDDRKTQVWGCQFEPDINNPG-KTTSICATCGGDSVCFIDCSTGQVLKKYKQPGETFYCIAWSTVTADINGNKRKANLLAAGGSDRTIKIIEPTQLVCIEDIPGIKGVLESLLFHPCNSTWLGCA-ADDTITIWEIGLPSGLGYGTKSKLLLTL----KSRTIVRFFAFAPHGMVVVGACDDGCYLWKLADMDPTN-DKPRIPFGSLEFPGKRSVPLDCVQCLSDSLIATKRVQEGSI-------CIWHSESNMMKNDFSLVLKV----PWRKTETPFLKFSFILECEVLVAGDDQGCVWLYDMMRFTPYTEKQSRKYEVMEQTQILLCP-------NDSTKVFNQV----------CANTSLD--YIVAVADTNVVCMW 621
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Medaka
Match: lrwd1 (leucine rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:101163993]) HSP 1 Score: 192.586 bits (488), Expect = 4.069e-50 Identity = 115/401 (28.68%), Postives = 198/401 (49.38%), Query Frame = 1
Query: 4537 PLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS-VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYIN-----ILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQL-LTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVW-----LFPEFRKHKPD-DIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
PLH ++CH++ ++ D TT++W CAF P ++ S +VATCGG+ VC+IDC TG VMK++K EEF+++AW+TV M+ G + +LAA GK ++L+HP + Y E + + ++ + FH + LF+G ++MWDIG + Y + +L+ + P+ + S + L+ CEDG+F + + D +I P +E + H+ DG++ L++ K I+ ++ + + RK ++ A ++ +L+W TD Y+ + G + CGD +G IW Y + + +N + P +L+WP + + P IN V M + TY+VA++D N+V IW
Sbjct: 356 PLHVLQCHSKQDSSEDFTTQLWACAFHPALDSSDSGGGSRLVATCGGDSVCVIDCETGMVMKKYKVPGEEFFSLAWSTVLMSRGSKASAQPCAVLAAGGKRGLVKLIHPRNNLAYGEFRASRKALSVLRFHRQKENFLFTGSYDNKIVMWDIG-----GIDSQYNFKVVQLLALESRTTPLHICLPPTSNNLLLVACEDGLFCYNTQLGTSSTTKSRSMDMEITFPIYEKEDEDHEYHTVDGMSFLNDDLVASKNYMHSCIYLWSWSRTVAQRPDRK---SRKVCAVIVAELQWAKTDIPYLALNTCPGRGYIVCGDEKGRIWTYHAA-NLQKNGYQTGKPIPPTDVLEWPAPRRKGLGSLE-----------GPSINSVAMDPELTYMVALSDKNMVIIW 736
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Medaka
Match: lrwd1 (leucine rich repeats and WD repeat domain containing 1 [Source:NCBI gene;Acc:101163993]) HSP 1 Score: 192.586 bits (488), Expect = 4.069e-50 Identity = 115/401 (28.68%), Postives = 198/401 (49.38%), Query Frame = 1
Query: 4537 PLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTS-VVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYIN-----ILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQL-LTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVW-----LFPEFRKHKPD-DIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIW 5700
PLH ++CH++ ++ D TT++W CAF P ++ S +VATCGG+ VC+IDC TG VMK++K EEF+++AW+TV M+ G + +LAA GK ++L+HP + Y E + + ++ + FH + LF+G ++MWDIG + Y + +L+ + P+ + S + L+ CEDG+F + + D +I P +E + H+ DG++ L++ K I+ ++ + + RK ++ A ++ +L+W TD Y+ + G + CGD +G IW Y + + +N + P +L+WP + + P IN V M + TY+VA++D N+V IW
Sbjct: 356 PLHVLQCHSKQDSSEDFTTQLWACAFHPALDSSDSGGGSRLVATCGGDSVCVIDCETGMVMKKYKVPGEEFFSLAWSTVLMSRGSKASAQPCAVLAAGGKRGLVKLIHPRNNLAYGEFRASRKALSVLRFHRQKENFLFTGSYDNKIVMWDIG-----GIDSQYNFKVVQLLALESRTTPLHICLPPTSNNLLLVACEDGLFCYNTQLGTSSTTKSRSMDMEITFPIYEKEDEDHEYHTVDGMSFLNDDLVASKNYMHSCIYLWSWSRTVAQRPDRK---SRKVCAVIVAELQWAKTDIPYLALNTCPGRGYIVCGDEKGRIWTYHAA-NLQKNGYQTGKPIPPTDVLEWPAPRRKGLGSLE-----------GPSINSVAMDPELTYMVALSDKNMVIIW 736
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Medaka
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:100049503]) HSP 1 Score: 53.1434 bits (126), Expect = 2.165e-6 Identity = 35/112 (31.25%), Postives = 52/112 (46.43%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++ + C GH I + FHPR P +L S + +W+I
Sbjct: 115 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDTNTSH--PLLAVAGSRGIIRVINHITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 223
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Medaka
Match: eed (embryonic ectoderm development [Source:NCBI gene;Acc:100049503]) HSP 1 Score: 52.7582 bits (125), Expect = 2.309e-6 Identity = 35/112 (31.25%), Postives = 52/112 (46.43%), Query Frame = 1
Query: 4654 VVATCGGECVCLIDCRTGKVMKRFKS-----REEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDI 4974
V AT G V L +C + ++ +S +E FYT AWT + H +LA AG IR+++ + C GH I + FHPR P +L S + +W+I
Sbjct: 109 VFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWT-YDTNTSH--PLLAVAGSRGIIRVINHITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNI 217
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Planmine SMEST
Match: SMESG000061887.1 (SMESG000061887.1) HSP 1 Score: 3596.98 bits (9326), Expect = 0.000e+0 Identity = 1863/1869 (99.68%), Postives = 1865/1869 (99.79%), Query Frame = 1
Query: 106 MDMDEGEIYFEKETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVISNTTNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPNVFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNEEEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGFENNNDLPAVQPYSEALGSLTAYQELVGLVERYKSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRTGLYPIDTGRNEARDELVDETIGYSDVSAQIDEXXXXXXXXXXRSYPPTTLIAGSGGGYMNTDMSSSHPFGQGGVFSNFGKRDLQLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSTKSRYQRKNEFDNQTVEKDQILLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPVXXXXXXXXXXSSYLVSASNKKSAIDGTTGTGEESKKDRFSEPTRTRPGPASFKKRVYGITQSPPPETDDDIFTKETVQKVIDDVLQKVENFNTNVKRRVGRPKTIKTNMEKPKEKVLKENVEMQKRDLFKIPKSMQDNSDWTNDNDNMDVVREKRPNSPVSQDILRKVAEIVRDCTTPIPPSKLREMAGIGTRGRPPRFIKEASDRTYIKLNKTIPETPTKQKLPIGEDDSLGILIDESILNLTPHRPPPQTLQVTTRDSNRMKRFNPYGVRESNESVTNFSSDNEELRNSPGEVREGNDDYEYAXXXXXXXXXXXXXXXXXLRTNSDQSDFNSESSFINELKRNQYEKEKHKILQKXXXXXXXXXXXXXFKPNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSIPT 5712
MDMDEGEIYFEKETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVISNTTNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPNVFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNEEEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGFENNNDLPAVQPYSEALGSLTAYQELVGLVERYKSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRTGLYPIDTGRNEARDELVDETIGYSDVSAQIDESHVVSVG SGRSYPPTTLIAGSGGGYMNTDMSSSHPFGQGGVFSNFGKRDLQLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSDNDDDDDEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCLFLPNLIKLNLKKNAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTL+EARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVFNEEKFFNFKDLVARRVAESFLDSKIIDDDDDEELKDKYNDENEDDDDEEQSEISRSTKSRYQRKNEFDNQTVEKDQILLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPVGGGDNNQNNNSSYLVSASNKKS IDGTTGTGEESKKDRFSEPTRTRPGPASFKKRVYGITQSPPPETDDDIFTKETVQKVIDDVLQKVENFNTNVKRRVGRPKTIKTNMEKPKEKVLKENVEMQKRDLFKIPKSMQDNSDWTNDNDNMDVVREKRPNSPVSQDILRKVAEIVRDCTTPIPPSKLREMAGIGTRGRPPRFIKEASDRTYIK NKTIPETPTKQKLPIGEDDSLGILIDESILNLTPHRPPPQTLQVTTRDSNRMKRFNPYGVRESNESVTNFSSDNEELRNSPGEVREG DDYEYAPSPKQSKSTSISPTKSSLRTNSDQSDFNSESSFINELKRNQYEKEKHKILQKSSSVIVSLPASSIFKPNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTND+DKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSIPT
Sbjct: 1 MDMDEGEIYFEKETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVISNTTNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPNVFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNEEEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGFENNNDLPAVQPYSEALGSLTAYQELVGLVERYKSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRTGLYPIDTGRNEARDELVDETIGYSDVSAQIDESHVVSVGVSGRSYPPTTLIAGSGGGYMNTDMSSSHPFGQGGVFSNFGKRDLQLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSDNDDDDDEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCLFLPNLIKLNLKKNAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLVEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVFNEEKFFNFKDLVARRVAESFLDSKIIDDDDDEELKDKYNDENEDDDDEEQSEISRSTKSRYQRKNEFDNQTVEKDQILLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPVGGGDNNQNNNSSYLVSASNKKSTIDGTTGTGEESKKDRFSEPTRTRPGPASFKKRVYGITQSPPPETDDDIFTKETVQKVIDDVLQKVENFNTNVKRRVGRPKTIKTNMEKPKEKVLKENVEMQKRDLFKIPKSMQDNSDWTNDNDNMDVVREKRPNSPVSQDILRKVAEIVRDCTTPIPPSKLREMAGIGTRGRPPRFIKEASDRTYIKHNKTIPETPTKQKLPIGEDDSLGILIDESILNLTPHRPPPQTLQVTTRDSNRMKRFNPYGVRESNESVTNFSSDNEELRNSPGEVREGYDDYEYAPSPKQSKSTSISPTKSSLRTNSDQSDFNSESSFINELKRNQYEKEKHKILQKSSSVIVSLPASSIFKPNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDNDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSIPT 1869
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Planmine SMEST
Match: SMESG000061887.1 (SMESG000061887.1) HSP 1 Score: 3561.54 bits (9234), Expect = 0.000e+0 Identity = 1849/1869 (98.93%), Postives = 1851/1869 (99.04%), Query Frame = 1
Query: 106 MDMDEGEIYFEKETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVISNTTNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPNVFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNEEEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGFENNNDLPAVQPYSEALGSLTAYQELVGLVERYKSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRTGLYPIDTGRNEARDELVDETIGYSDVSAQIDEXXXXXXXXXXRSYPPTTLIAGSGGGYMNTDMSSSHPFGQGGVFSNFGKRDLQLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSTKSRYQRKNEFDNQTVEKDQILLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPVXXXXXXXXXXSSYLVSASNKKSAIDGTTGTGEESKKDRFSEPTRTRPGPASFKKRVYGITQSPPPETDDDIFTKETVQKVIDDVLQKVENFNTNVKRRVGRPKTIKTNMEKPKEKVLKENVEMQKRDLFKIPKSMQDNSDWTNDNDNMDVVREKRPNSPVSQDILRKVAEIVRDCTTPIPPSKLREMAGIGTRGRPPRFIKEASDRTYIKLNKTIPETPTKQKLPIGEDDSLGILIDESILNLTPHRPPPQTLQVTTRDSNRMKRFNPYGVRESNESVTNFSSDNEELRNSPGEVREGNDDYEYAXXXXXXXXXXXXXXXXXLRTNSDQSDFNSESSFINELKRNQYEKEKHKILQKXXXXXXXXXXXXXFKPNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSIPT 5712
MDMDEGEIYFEKETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVISNTTNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPNVFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNEEEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGFENNNDLPAVQPYSEALGSLTAYQELVGLVERYKSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRTGLYPIDTGRNEARDELVDETIGYSDVSAQIDESHVVSVG SGRSYPPTTLIAGSGGGYMNTDMSSSHPFGQGGVFSNFGKRDLQLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSDNDDDDDEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCLFLPNLIKLNLKKNAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTL+EARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVFNEEKFFNFKDLVARRVAESFLDSKIIDDDDDEELKDKYNDENEDDDDEEQSEISRSTKSRYQRKNEFDNQTVEKDQILLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPVGGGDNNQNNNSSYLVSASNKKS IDGTTGTGEESKKDRFSEPTRTRPGPASFKKRVYGITQSPPPETDDDIFTKETVQKVIDDVLQKVENFNTNVKRRVGRPKTIKTNMEKPKEKVLKENVEMQKRDLFKIPKSMQDNSDWTNDNDNMDVVREKRPNSPVSQDILRKVAEIVRDCTTPIPPSKLREMAGIGTRGRPPRFIKEASDRTYIK NKTIPETPTKQKLPIGEDDSLGILIDESILNLTPHRPPPQTLQVTTRDSNRMKRFNPYG NEELRNSPGEVREG DDYEYAPSPKQSKSTSISPTKSSLRTNSDQSDFNSESSFINELKRNQYEKEKHKILQKSSSVIVSLPASSIFKPNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTND+DKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSIPT
Sbjct: 1 MDMDEGEIYFEKETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECTLSKYIDEDGKPQFMLVEANESESDSINTLNKVISNTTNLHSISKADEMGILIDNQQDIKNIVGDVSHVKNRESLELDQQFENKLAVTDNEEQIQGEQFLISEYPTTTPNVFTVVITDSNGENIFEKDGDLGETIILELLGHTISYVISGINEDGSTRETNVFFDSSETDKTNEVNEGIPRQTLMPLEQGPINDDTSQQEPVDNNEEEYVITEQSVINDGQPKQKVTLAGKSRVILDEKYGLKGDSVKLQLTDKAFEYVIQGPMENGEPIVTTFLINRGDDDEVEESEHQNSEADDPAALWGPSELSKEEYAAIREQSRSVAAGFENNNDLPAVQPYSEALGSLTAYQELVGLVERYKSKDEERKNDLMMLRRHSKLYIPARPNARRLTPLEYARNEAAAQVCRYVPALLFHKRRLYDCAVMAVDRTGLYPIDTGRNEARDELVDETIGYSDVSAQIDESHVVSVGVSGRSYPPTTLIAGSGGGYMNTDMSSSHPFGQGGVFSNFGKRDLQLNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSDNDDDDDEEIYRPREFRDSELLGNVNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCLFLPNLIKLNLKKNAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLVEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVFNEEKFFNFKDLVARRVAESFLDSKIIDDDDDEELKDKYNDENEDDDDEEQSEISRSTKSRYQRKNEFDNQTVEKDQILLQDEPLDRLTNVVGQALRSGKTVVYSVMRTAARQPGGDLIPVGGGDNNQNNNSSYLVSASNKKSTIDGTTGTGEESKKDRFSEPTRTRPGPASFKKRVYGITQSPPPETDDDIFTKETVQKVIDDVLQKVENFNTNVKRRVGRPKTIKTNMEKPKEKVLKENVEMQKRDLFKIPKSMQDNSDWTNDNDNMDVVREKRPNSPVSQDILRKVAEIVRDCTTPIPPSKLREMAGIGTRGRPPRFIKEASDRTYIKHNKTIPETPTKQKLPIGEDDSLGILIDESILNLTPHRPPPQTLQVTTRDSNRMKRFNPYG--------------NEELRNSPGEVREGYDDYEYAPSPKQSKSTSISPTKSSLRTNSDQSDFNSESSFINELKRNQYEKEKHKILQKSSSVIVSLPASSIFKPNPQCKGISVNGKTPDYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNHTRKFKCKPAKILDWPECSVESTNDNDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSIPT 1855
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Planmine SMEST
Match: SMESG000073045.1 (SMESG000073045.1) HSP 1 Score: 419.468 bits (1077), Expect = 7.468e-124 Identity = 206/406 (50.74%), Postives = 268/406 (66.01%), Query Frame = 1
Query: 4528 DYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPE-YTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKV-------PTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNE--NNHTRKFKCKPAKILDWPECSV---ESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
DYDPLHFIRCHA+DN PLD TKVWRC FEPNPN P +TT +VATCGGECVCLIDC+ GKVMKRFK +EEF T+AWTT+E+ G +NILAAAGK+K+IRLL P+ + Y +M+GH+++I+ + FHP P +LFSGD A+V +WDIG PSA + YQLL +L CPR +NPVLNLV + Y L+ GCEDG+F W E+R K + + PD E+K+ T +DGLA+LS + + K V + +F L+ K Q + D+ G L WQ T++ YINVTA+ NLG+V CGD+ G IW+YD+ + E +R F C P K+L+WPEC+V E IN E K+P+IN V++SSDG Y++AVTDNNLVCIW +
Sbjct: 680 DYDPLHFIRCHAKDNAPLDQDTKVWRCVFEPNPNQPN-QTTHIVATCGGECVCLIDCKVGKVMKRFKREDEEFMTLAWTTLEIEPGKRLNILAAAGKLKEIRLLFPD-FLHYCDMRGHQEDISALVFHPSMPQILFSGDTKASVFIWDIGTPSANQSRLMRYQLLMRLRCPRLDVNPVLNLVFLDHYSYLVAGCEDGIFAWKITEYRSEKRE--REPDMELKLFVDDKIDVTLDSISYDGLAQLSRTALVFKIVHNPNLLVFDFGTTLERRKGL----QKVVPIDICGTLTWQKTEDFYINVTARQNLGAVLCGDSVGNIWIYDLDPFIEECPERISRDFVCSPYKVLEWPECNVTGNERQISEQGINTSPEL--KSPVINTVDLSSDGLYIIAVTDNNLVCIWQL 1075 HSP 2 Score: 135.576 bits (340), Expect = 1.638e-31 Identity = 117/433 (27.02%), Postives = 214/433 (49.42%), Query Frame = 1
Query: 1789 LNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGNVN----IECEAEH--NILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
L E +I NAA + ++ +K S C E + + R+ + ++ Y+R+ S ++GRF PL+PY++ VNEAA L++ LLT +++L+D A++VV+ SG K++ S++ PE LS R G + +NS + + V SD+ + E+ R D +L ++N IE + E ILNE I ++ + L +VR+L + ++T + ++ C L EL+ N +S PR L LP L L + N F+ PL+EQFP L + D K + +N +++SFFCP+L +IN + FE +++ F+ ++EA+ ++ +++++WE + + + E +I+ +V +++R + ++ +KDL+ + E +L
Sbjct: 11 LTEEEVDSIANAA--MNVKIPSVELKESSKCNILENYLHSDAERICGF---DQKALDDQFPYIRDVSVIHGRFANGPINPRCPLTPYEMGVNEAAAWLIRRAPALLTHQRLLSDLARQVVKNSGLNL--------KQFKSSSQQSNQFYQTPERRLSSNARSGIHYRLQGQYRNSVNS-----LMDADVISDDITMINRELSR----NDVTILNSMNDDIRIEMQLEEVDKILNEEEILKYSSSTKLDEVRVLKIPCNNYTVIESRNLAKCVRLRELDFSENLLSEFPRDLNLPKLKYLEMTGNRFMQQPLIEQFPNLVVLNFDEKFKQNMNFQAMSFFCPKLKFINGEYFEEPINEYFHTYIMEAKMALDPIIRNKWESEFADRCPNILNNQERMSLIDEMVQQLKDRNLLIDDNLSKYKDLLIFKFTEEYL 421
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Planmine SMEST
Match: SMESG000073045.1 (SMESG000073045.1) HSP 1 Score: 419.853 bits (1078), Expect = 7.482e-124 Identity = 206/406 (50.74%), Postives = 268/406 (66.01%), Query Frame = 1
Query: 4528 DYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPE-YTTHYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKV-------PTHQEPCFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNE--NNHTRKFKCKPAKILDWPECSV---ESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
DYDPLHFIRCHA+DN PLD TKVWRC FEPNPN P +TT +VATCGGECVCLIDC+ GKVMKRFK +EEF T+AWTT+E+ G +NILAAAGK+K+IRLL P+ + Y +M+GH+++I+ + FHP P +LFSGD A+V +WDIG PSA + YQLL +L CPR +NPVLNLV + Y L+ GCEDG+F W E+R K + + PD E+K+ T +DGLA+LS + + K V + +F L+ K Q + D+ G L WQ T++ YINVTA+ NLG+V CGD+ G IW+YD+ + E +R F C P K+L+WPEC+V E IN E K+P+IN V++SSDG Y++AVTDNNLVCIW +
Sbjct: 681 DYDPLHFIRCHAKDNAPLDQDTKVWRCVFEPNPNQPN-QTTHIVATCGGECVCLIDCKVGKVMKRFKREDEEFMTLAWTTLEIEPGKRLNILAAAGKLKEIRLLFPD-FLHYCDMRGHQEDISALVFHPSMPQILFSGDTKASVFIWDIGTPSANQSRLMRYQLLMRLRCPRLDVNPVLNLVFLDHYSYLVAGCEDGIFAWKITEYRSEKRE--REPDMELKLFVDDKIDVTLDSISYDGLAQLSRTALVFKIVHNPNLLVFDFGTTLERRKGL----QKVVPIDICGTLTWQKTEDFYINVTARQNLGAVLCGDSVGNIWIYDLDPFIEECPERISRDFVCSPYKVLEWPECNVTGNERQISEQGINTSPEL--KSPVINTVDLSSDGLYIIAVTDNNLVCIWQL 1076 HSP 2 Score: 135.576 bits (340), Expect = 1.545e-31 Identity = 117/433 (27.02%), Postives = 214/433 (49.42%), Query Frame = 1
Query: 1789 LNNSEETAIKNAAERLQEELYQYPIKPKSDCTAFELQIRDEIPRLQAMLDGNPSEVEQAMEYMRETSAVNGRFLPTQRTRHQPLSPYDVAVNEAAYHLVKNNIGLLTFRKVLADFAKKVVRASGCTFRHNTMGDKKEYNSANLWLYNQENVPELDLSPAVRVLSDSLEDGPLTSLMNSTFVPIIEETAVKSXXXXXXXEEIYRPREFRDSELLGNVN----IECEAEH--NILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
L E +I NAA + ++ +K S C E + + R+ + ++ Y+R+ S ++GRF PL+PY++ VNEAA L++ LLT +++L+D A++VV+ SG K++ S++ PE LS R G + +NS + + V SD+ + E+ R D +L ++N IE + E ILNE I ++ + L +VR+L + ++T + ++ C L EL+ N +S PR L LP L L + N F+ PL+EQFP L + D K + +N +++SFFCP+L +IN + FE +++ F+ ++EA+ ++ +++++WE + + + E +I+ +V +++R + ++ +KDL+ + E +L
Sbjct: 12 LTEEEVDSIANAA--MNVKIPSVELKESSKCNILENYLHSDAERICGF---DQKALDDQFPYIRDVSVIHGRFANGPINPRCPLTPYEMGVNEAAAWLIRRAPALLTHQRLLSDLARQVVKNSGLNL--------KQFKSSSQQSNQFYQTPERRLSSNARSGIHYRLQGQYRNSVNS-----LMDADVISDDITMINRELSR----NDVTILNSMNDDIRIEMQLEEVDKILNEEEILKYSSSTKLDEVRVLKIPCNNYTVIESRNLAKCVRLRELDFSENLLSEFPRDLNLPKLKYLEMTGNRFMQQPLIEQFPNLVVLNFDEKFKQNMNFQAMSFFCPKLKFINGEYFEEPINEYFHTYIMEAKMALDPIIRNKWESEFADRCPNILNNQERMSLIDEMVQQLKDRNLLIDDNLSKYKDLLIFKFTEEYL 422
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Planmine SMEST
Match: SMESG000066671.1 (SMESG000066671.1) HSP 1 Score: 355.525 bits (911), Expect = 6.927e-104 Identity = 174/403 (43.18%), Postives = 248/403 (61.54%), Query Frame = 1
Query: 4528 DYDPLHFIRCHARDNNPLDCTTKVWRCAFEPNPNNPYLETTSVVATCGGECVCLIDCRTGKVMKRFKSREEEFYTVAWTTVEMAGGHYINILAAAGKMKDIRLLHPEQLVCYAEMKGHEQEIACMTFHPRYPTVLFSGDAMATVLMWDIGIPSAPEYT-THYQLLTKLMCPRAHLNPVLNLVVMPSYDALITGCEDGVFVWLFPEFRKHKPDDIQHPDFEVKVPTHQEP-------CFDGLARLSESTFLVKCVEEGEIFTINFPQILQHYKARKFDEQNRIVADVIGQLRWQITDEIYINVTAQMNLGSVTCGDNEGTIWLYDMSKEVNENNH--TRKFKCKPAKILDWPECSVESTNDSDKINQDTETVNKNPIINCVEMSSDGTYLVAVTDNNLVCIWSI 5706
DYDPLHFIRCHA+D+ P D TKVWRC F P+ P TT VATCGGE VC+IDC GKV+ R+K E+F +AWT++E+ G +INILAA GK K+IRL ++ + ++KGH ++++ + FHP P +LFSGDA A++ +WDIG+PS + + +Q+L +L CPR LNPV+NLV + Y LI GC+D +F W +F+ K + + PD E++ + +DGLA++ + + + V+ F I+F IL+ K Q I + G L W +D+ YIN++++ NLG+V GD+ G IW+YD+ + EN T F C P ++LDWPEC++ D E K P+IN V+MSSDG ++V VTDNNLVCIW +
Sbjct: 467 DYDPLHFIRCHAKDSAPNDQETKVWRCGFAPSTKVPG-TTTHFVATCGGEVVCVIDCDCGKVVNRYKREGEDFIALAWTSLEIEPGLFINILAAGGKSKEIRLFFSDR-ESFLDLKGHPEDVSSLIFHPSVPQILFSGDAKASIFVWDIGMPSKHQTSLVRFQMLMRLRCPRPDLNPVMNLVFLDHYSYLIAGCDDAMFAWKITDFKGDKKE--REPDMELRFTESNKAGIPIDSISYDGLAQIGRTALVFRVVDNQNFFVIDFGTILERRKGL----QKTIPIETCGTLDWLRSDDFYINISSRNNLGAVLSGDSMGRIWIYDLDPYIEENPEKVTNGFHCLPCRVLDWPECNIGGPTD--------ENSPKLPVINTVDMSSDGLFVVGVTDNNLVCIWKL 853 HSP 2 Score: 88.5817 bits (218), Expect = 3.379e-17 Identity = 60/212 (28.30%), Postives = 118/212 (55.66%), Query Frame = 1
Query: 2434 VNIECEAEHNILNECVIYCHTGTDDLKKVRILDLANCSFTSLMPIDINYCYNLVELNLFNNSISYLPRCXXXXXXXXXXXXXXAFVTVPLLEQFPKLYSVELDNKVARKLNKESLSFFCPELTYINEKKFEGYLSDEFNNTLIEARTYIESMVQSRWEEDLSMYFKKGVAKSEAQKVIETLVLSIRERKVXXXXXXXXXXDLVARRVAESFL 3069
+++ E I++E I T L +V + L S+T + D++ CYNL EL+L N ++ R + LPNL L++ +N F PL+EQFP L + +D+ + +N +++++FCP L IN +KFE + D F N + A +E++++++WE +++ + + +I+ +V +++R + +E ++DL+ ++ E +L
Sbjct: 18 IDMTVEEVDKIIDEEEILYITKATSLNEVFEIKLPGKSYTLINSTDLSRCYNLRELDLSGNLLTEFSRSINLPNLKVLDISQNNFSQKPLVEQFPNLIVLVVDHNMKLNMNTDAVAYFCPNLKIINGEKFEVTVPDHFMNYITNASRALETIIRNKWENEIAERCYDILDNDHRRALIDEMVRQLKDRNLLIDEHLSKYRDLLIFKLTEKYL 229 The following BLAST results are available for this feature:
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of Leucine-rich repeat and WD repeat-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030320 ID=SMED30030320|Name=Leucine-rich repeat and WD repeat-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=5881bpback to top protein sequence of SMED30030320-orf-1 >SMED30030320-orf-1 ID=SMED30030320-orf-1|Name=SMED30030320-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1870bp MDMDEGEIYFEKETGETLVKVNIVDDNNPDESTYAMINKVCYDRLMKGECback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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