ABC transporter domain-containing protein

Overview
NameABC transporter domain-containing protein
Smed IDSMED30030306
Length (bp)2992
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ABC transporter domain-containing protein (SMED30030306) t-SNE clustered cells

Violin plots show distribution of expression levels for ABC transporter domain-containing protein (SMED30030306) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ABC transporter domain-containing protein (SMED30030306) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ABC transporter domain-containing protein (SMED30030306) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30030306

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30030306h1SMcG0013719 SmedASXL_016389SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30030306h1SMcG0013719 SmedASXL_016388SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30030306h1SMcG0013719 dd_Smed_v4_4225_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30030306h1SMcG0013719 dd_Smed_v4_4225_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30030306h1SMcG0013719 dd_Smed_v4_4225_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30030306h1SMcG0013719 dd_Smed_v4_4225_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30030306h1SMcG0013719 dd_Smed_v4_4225_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30030306h1SMcG0013719 dd_Smed_v4_4225_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of ABC transporter domain-containing protein vs. Ensembl Human
Match: ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group) [Source:HGNC Symbol;Acc:HGNC:74])

HSP 1 Score: 323.939 bits (829), Expect = 1.168e-138
Identity = 206/509 (40.47%), Postives = 302/509 (59.33%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISC---YVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RGVSGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A G++++HG +  A L YF + GYH E +NNPADF++DI+NG+           ++ +R      E   + +E+    +  SK  +P          +IEKL   +  S  +KE + +L+      +       +     I+Y TS+ +Q++W+  R+  NLL NPQ S  Q+ V +     +G +YFGLK + S   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYF  KLL D++P+++ P+I+F  I YFM GL+  A AFF     L++   +  S+A  ++A  SV  +A ++  I +VFMM+FSG  +N+++I SWL W QY S  R+    L  NE   Q  C  L    N  C     TG  +L + G   L PW LWKN + L  + + FL + Y++L  + KY
Sbjct:  181 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEA-LGYFESAGYHCEAYNNPADFFLDIINGD--------STAVALNR------EEDFKATEI----IEPSKQDKP----------LIEKLAEIYVNSSFYKETKAELHQLSGGEKKKKITVFK----EISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKND-STGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGI-DLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 654          

HSP 2 Score: 191.815 bits (486), Expect = 1.168e-138
Identity = 92/149 (61.74%), Postives = 118/149 (79.19%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK--YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K  T+G+++SFH+I Y+ K K    P  K V K IL+N+NG+M PG+NAI+GPTG GKSS+LDVLA RKDP  L G VLI+G P+P NFKC SGYVVQDD+VMGTLTVRENL+FSAALRL+T +T ++++ ++  +I+ELGL  VADSK
Sbjct:   29 KAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSK 177          
BLAST of ABC transporter domain-containing protein vs. Ensembl Human
Match: ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group) [Source:HGNC Symbol;Acc:HGNC:74])

HSP 1 Score: 323.939 bits (829), Expect = 1.168e-138
Identity = 206/509 (40.47%), Postives = 302/509 (59.33%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISC---YVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RGVSGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A G++++HG +  A L YF + GYH E +NNPADF++DI+NG+           ++ +R      E   + +E+    +  SK  +P          +IEKL   +  S  +KE + +L+      +       +     I+Y TS+ +Q++W+  R+  NLL NPQ S  Q+ V +     +G +YFGLK + S   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYF  KLL D++P+++ P+I+F  I YFM GL+  A AFF     L++   +  S+A  ++A  SV  +A ++  I +VFMM+FSG  +N+++I SWL W QY S  R+    L  NE   Q  C  L    N  C     TG  +L + G   L PW LWKN + L  + + FL + Y++L  + KY
Sbjct:  181 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEA-LGYFESAGYHCEAYNNPADFFLDIINGD--------STAVALNR------EEDFKATEI----IEPSKQDKP----------LIEKLAEIYVNSSFYKETKAELHQLSGGEKKKKITVFK----EISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKND-STGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGI-DLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 654          

HSP 2 Score: 191.815 bits (486), Expect = 1.168e-138
Identity = 92/149 (61.74%), Postives = 118/149 (79.19%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK--YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K  T+G+++SFH+I Y+ K K    P  K V K IL+N+NG+M PG+NAI+GPTG GKSS+LDVLA RKDP  L G VLI+G P+P NFKC SGYVVQDD+VMGTLTVRENL+FSAALRL+T +T ++++ ++  +I+ELGL  VADSK
Sbjct:   29 KAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSK 177          
BLAST of ABC transporter domain-containing protein vs. Ensembl Human
Match: ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group) [Source:HGNC Symbol;Acc:HGNC:74])

HSP 1 Score: 274.248 bits (700), Expect = 6.080e-124
Identity = 168/404 (41.58%), Postives = 249/404 (61.63%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMV 2271
            + +RGVSGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A G++++HG +  A L YF + GYH E +NNPADF++DI+NG+           ++ +R      E   + +E+    +  SK  +P          +IEKL   +  S  +KE + +L+      +       +     I+Y TS+ +Q++W+  R+  NLL NPQ S  Q+ V +     +G +YFGLK + S   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYF  KLL D++P+++ P+I+F  I YFM GL+  A AFF     L++   +  S+A  ++A  SV  +A ++  I +VFMMV
Sbjct:  181 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEA-LGYFESAGYHCEAYNNPADFFLDIINGD--------STAVALNR------EEDFKATEI----IEPSKQDKP----------LIEKLAEIYVNSSFYKETKAELHQLSGGEKKKKITVFK----EISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKND-STGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMV 550          

HSP 2 Score: 192.586 bits (488), Expect = 6.080e-124
Identity = 92/149 (61.74%), Postives = 118/149 (79.19%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK--YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K  T+G+++SFH+I Y+ K K    P  K V K IL+N+NG+M PG+NAI+GPTG GKSS+LDVLA RKDP  L G VLI+G P+P NFKC SGYVVQDD+VMGTLTVRENL+FSAALRL+T +T ++++ ++  +I+ELGL  VADSK
Sbjct:   29 KAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSK 177          
BLAST of ABC transporter domain-containing protein vs. Ensembl Human
Match: ABCG4 (ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884])

HSP 1 Score: 142.51 bits (358), Expect = 1.211e-49
Identity = 114/430 (26.51%), Postives = 206/430 (47.91%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGL 2364
            +SGG+RKR  I +EL+ +P V+F DEPT+GLD+ +   V+  ++ L++ G+TII +IHQP   ++++FD+  I+++G+ I+ G   +  + Y   LG H   ++NPADF I++                           +SGEY ++  ML    + G       ++KK   EK         N           +V   +           S T+ATS   Q   L  RT +++LR+   + ++   ++     +G++Y  +  +AS    N   LFF     +    +  +  F  E  +F+ E+ + +Y + +Y+ +K + D VP +V   +V+  I Y+M G   +   F  F  +   T     S+   + A+ +   +A  V P+  + +++FSG+F++  +I ++LQW  YLS  R+   G+
Sbjct:  201 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNL-IPYLKGLGLHCPTYHNPADFIIEV---------------------------ASGEYGDLNPMLFRAVQNGLCA---MAEKKSSPEK---------NEVPAPCPPCPPEVDPIE-----------SHTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMAD-VPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGV 578          

HSP 2 Score: 76.2554 bits (186), Expect = 1.211e-49
Identity = 46/142 (32.39%), Postives = 85/142 (59.86%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLP-GVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQP-QPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSKN 1063
            I F  +SY  +     W K   K +L  ++G      +  IMGP+G+GKS+ +++LAG ++   ++G++L++G+P + + F+ MS Y++QDD+++  LTV E +  SA L+LS +  +  +   VT I+  LGL + + ++ 
Sbjct:   61 IEFVELSYSVREGP-CWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG-MKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRT 198          
BLAST of ABC transporter domain-containing protein vs. Ensembl Human
Match: ABCG4 (ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884])

HSP 1 Score: 142.51 bits (358), Expect = 1.211e-49
Identity = 114/430 (26.51%), Postives = 206/430 (47.91%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGL 2364
            +SGG+RKR  I +EL+ +P V+F DEPT+GLD+ +   V+  ++ L++ G+TII +IHQP   ++++FD+  I+++G+ I+ G   +  + Y   LG H   ++NPADF I++                           +SGEY ++  ML    + G       ++KK   EK         N           +V   +           S T+ATS   Q   L  RT +++LR+   + ++   ++     +G++Y  +  +AS    N   LFF     +    +  +  F  E  +F+ E+ + +Y + +Y+ +K + D VP +V   +V+  I Y+M G   +   F  F  +   T     S+   + A+ +   +A  V P+  + +++FSG+F++  +I ++LQW  YLS  R+   G+
Sbjct:  201 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNL-IPYLKGLGLHCPTYHNPADFIIEV---------------------------ASGEYGDLNPMLFRAVQNGLCA---MAEKKSSPEK---------NEVPAPCPPCPPEVDPIE-----------SHTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMAD-VPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGV 578          

HSP 2 Score: 76.2554 bits (186), Expect = 1.211e-49
Identity = 46/142 (32.39%), Postives = 85/142 (59.86%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLP-GVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQP-QPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSKN 1063
            I F  +SY  +     W K   K +L  ++G      +  IMGP+G+GKS+ +++LAG ++   ++G++L++G+P + + F+ MS Y++QDD+++  LTV E +  SA L+LS +  +  +   VT I+  LGL + + ++ 
Sbjct:   61 IEFVELSYSVREGP-CWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG-MKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRT 198          
BLAST of ABC transporter domain-containing protein vs. Ensembl Celegans
Match: wht-8 (WHiTe (Drosophila) related ABC transporter [Source:UniProtKB/TrEMBL;Acc:Q9U2D0])

HSP 1 Score: 155.992 bits (393), Expect = 5.314e-56
Identity = 123/460 (26.74%), Postives = 208/460 (45.22%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLS-RSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLA-NVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK-DQCYTLKTFPNISCYVTGN 2439
            +G+SGGE KR     E+I +P +IF DEPTTGLD+  +  V+KTL++++   GKTII +IHQP   ++++FD+   +A+G+I +HG    A +++F + GY +  H NPAD++ID L                      A+  S  E  + +                        ++L   +E+S   + L +       + +   D     P  S TY       +  L +R  ++ +RNP     +L   LF    +G +++GL+ +       +  LF++ +        G       + P  + E     Y +S+Y+ +K +C  +PI     I+ +  +YF+ G   D G F       +       ++   V A+   + +A  V  P++ VF +   G F NI+ + +W+ W QYLS FR+    L VN+ + DQ      F NI+C    N
Sbjct:  173 KGISGGEMKRLAFATEMINNPPIIFCDEPTTGLDSHMSLQVVKTLEQMALEKGKTIICTIHQPSSEVFEIFDKVVFLAQGRIAFHGAIDEA-IHHFSSCGYQVPDHTNPADYFIDTL----------------------AIKPSEAEACKSR-----------------------CQELCDKFEKSFYNERLTK-------LMDQTKDVRAMTPHHSATYPV----LLYALFYRYMLDNIRNPAIMKAKLIQKLFMGLFIGTLFYGLETDQDGLASYKGALFYYISELTYSTIFGIQAFMPADYPPLVREYDDRIYPISAYYIAK-ICSFLPIFTVDGIILVVSSYFLVGFPSDFGVFLRQIFTCMAIEWNVAALGIAVCATAPSYAIAVTVTGPLLTVFSLT-GGLFTNIAEMPAWINWVQYLSWFRYGYESLVVNQFQHDQ------FANITCNANMN 567          

HSP 2 Score: 82.8037 bits (203), Expect = 5.314e-56
Identity = 45/119 (37.82%), Postives = 75/119 (63.03%), Query Frame = 2
Query:  710 KIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKY-LEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +++LN V+G  +PG V A+MG +G+GK+++L+ L  R      +EG++L++GQ   K    +S YV Q+D+ MGTLTV+E+L+  A LRL    +   R+ +V  ++ E+ L    DS+
Sbjct:   47 RVLLNGVSGCAVPGEVIALMGASGAGKTTLLNTLLQRNLRGLQVEGEILVNGQNIGKGVTSVSAYVQQEDLFMGTLTVKEHLDIQAKLRLPPGTSTTARATRVNEVMNEMLLEKPRDSR 165          
BLAST of ABC transporter domain-containing protein vs. Ensembl Celegans
Match: wht-5 (WHiTe (Drosophila) related ABC transporter [Source:UniProtKB/TrEMBL;Acc:Q19585])

HSP 1 Score: 129.413 bits (324), Expect = 2.004e-46
Identity = 103/429 (24.01%), Postives = 191/429 (44.52%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLN--FKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSI------FSWLQWCQY 2331
            + +S GERKR     E++TDP ++F DEPT+GLD+F +  VIK L++L+  GKT+I +IHQP  S+Y + D+  ++++G + Y G +      +F   GY I    +  D ++ +++ +                      E+  +Y+  KR+                 +K+++E      E+S +      RR+                 P +   T+  +W+ Q  ++  R+++ L R      ++L   L  +  +G  Y+GL+++       +   F    +  +   + A+ +F K+ P+ + E  +  Y  S+Y+ +K   D +   VFP ++F  I   M  L         + +I +L +   CSV    +A          V PI+ V +MVF G+ +   +I      F+W+ W +Y
Sbjct:  242 KSLSRGERKRLAFACEILTDPPILFCDEPTSGLDSFMSHQVIKALRQLTIEGKTVICTIHQPSTSVYHMADQLILLSQGHVAYAGPAKQVD-AFFGRCGYPIPKFVSSPDHFMRVISHK--------------------SFETEDDYN--KRI-----------------EKIVLEHDIMKKEQSTHSTLSSSRRE----------------HPETAPFTFPRTWTAQFFFIFQRSSIQLWRERSVLLVKLIQTLIMSIMIGSTYYGLEIDKKSLPSFKGFAFVSVQMMHMLFMMPAMTVFWKDYPVVVREFQANMYSPSAYYLAKTTADSIQYLVFP-VIFSGILLGMTSLPYSVVIITNYLIINILLSLNACSVGQSFAAMCGHLATGMTVLPIVCVPLMVFGGFMITYEAIPWYFLPFAWVSWYKY 613          

HSP 2 Score: 77.411 bits (189), Expect = 2.004e-46
Identity = 60/202 (29.70%), Postives = 106/202 (52.48%), Query Frame = 2
Query:  479 PTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTP----TKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLE--GKVLIDGQPQPKN-FKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            P  +  N +PV   I+     +KE  +++E F++  ++    + +  + P    T    + F +I      KK      V + IL  ++GV  PG +  IMG +G+GK+++L++L GR + K +E  G ++I+G+    N  K +S YV QDD+ +GTLTVRE L F+A LR  + +   +  + V  ++  + L    ++K
Sbjct:   43 PIPVLINDTPVASEIEQV---EKELAHSSERFRKPKTLSVTNDTESARIPSQVKTNAKKLVFQNIQAVVLKKK-----GVRQEILKKIDGVARPGELTFIMGSSGAGKTTLLNILTGR-NLKNIETDGDIMINGRNMISNEMKKLSAYVQQDDVFIGTLTVRETLRFAAKLRSPSALGATELDSIVDELLVMMSLKKCENTK 235          
BLAST of ABC transporter domain-containing protein vs. Ensembl Celegans
Match: wht-4 (WHiTe (Drosophila) related ABC transporter [Source:UniProtKB/TrEMBL;Acc:O16574])

HSP 1 Score: 139.813 bits (351), Expect = 3.085e-46
Identity = 112/443 (25.28%), Postives = 203/443 (45.82%), Query Frame = 1
Query: 1066 LRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLG--YHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEES-LNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKD 2385
            ++G+S GE+KR     E++TDP ++F DEPT+GLDAF A+ V++ L  L+  GKTII+ +HQP  +++++F +   MA GK +YHG        +F  LG  + +    NPADF +  ++   + E+E                       +V R                      IE L ++++ S +  + L++   A D       D +         Y +++  Q + L  R+     R+P    ++    L  A  +GIV + ++++          ++  A          ++ +   E P+F+ E+ S  Y V +YF +K L ++    + P +++  I Y+MAGL     +F  F  + +  T    S+A+  +  F   GL     P+  + M+VF G+++N +SI  + Q+  ++S F+     L  N+ K+
Sbjct:  176 MKGISIGEKKRLAFACEILTDPKILFCDEPTSGLDAFMASEVVRALLDLANKGKTIIVVLHQPSSTVFRMFHKVCFMATGKTVYHGAVDRL-CPFFDKLGPDFRVPESYNPADFVMSEISISPETEQE-----------------------DVTR----------------------IEYLIHEYQNSDIGTQMLKKTRTAVDEFGGYGDDEDDGESR----YNSTFGTQFEILLKRSLRTTFRDPLLLRVRFAQILATAILVGIVNWRVELKGPTIQNLEGVMYNCARDMTFLFYFPSVNVITSELPVFLREHKSNIYSVEAYFLAKSLAELPQYTILP-MIYGTIIYWMAGLVASVTSFLVFVFVCITLTWVAVSIAYVGACIFGDEGLVVTFMPMFVLPMLVFGGFYVNANSIPVYYQYVSFVSWFKHGFEALEANQWKE 567          

HSP 2 Score: 66.2402 bits (160), Expect = 3.085e-46
Identity = 52/172 (30.23%), Postives = 91/172 (52.91%), Query Frame = 2
Query:  590 VDSLYNVDHRKTPTKGSIISFHSISYKAKSKK-YPWSKSVTKI---------ILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLA--GRKDPKYLEGKVLIDGQPQPKN-FKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSKN 1063
            + SL     R   +K ++I+  +     K +K   WS  V  +         ++ NV+GV  PG V A+MG +G+GK++++++LA       +YL G V ++G+   K   + M  YV Q D+  GTLTVRE L ++A +R+    T   +  +V N+++++ L+   D +N
Sbjct:    1 MQSLTTASMRDATSKSTMITVDTGDGSEKGRKTIAWSGLVATVPQAGGGRKEVIRNVSGVAEPGEVLALMGGSGAGKTTLMNILAHLDTNGVEYL-GDVTVNGKKITKQKMRQMCAYVQQVDLFCGTLTVREQLTYTAHMRMKNA-TVQQKMERVENVLRDMNLT---DCQN 167          
BLAST of ABC transporter domain-containing protein vs. Ensembl Celegans
Match: wht-6 (WHiTe (Drosophila) related ABC transporter [Source:UniProtKB/TrEMBL;Acc:Q22802])

HSP 1 Score: 133.65 bits (335), Expect = 4.418e-44
Identity = 109/437 (24.94%), Postives = 203/437 (46.45%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFI-KERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNE 2376
            +G+SGGE +R     E++++PS++F DEPTTGLD+F A SVI+ L+ ++++G+TII +IHQP   +Y++F R   +A G   + G    + +++F   G+ +    NP+++ I  L  +   EK+  D+                                             I+K+   +E+S + K +  QL+        D   +I PP +   +  +   Q+  L  R  +++ R PQ +  ++   + F   +G++Y     +A     N  G  FF A + ++    AI  F+  E P+   E   G Y + +Y+F++ +  ++P+     ++ L I Y++ GL           +I +L + A  +    +S  F    +  V+     V   +F G + N ++  + ++W Q++S +RFA  GL VN+
Sbjct:  172 KGISGGEARRLTFACEMLSNPSLLFADEPTTGLDSFMAESVIQILKGIAKTGRTIICTIHQPSSQLYQMFHRVIYLANGSTAFQGTPQES-ISFFEKCGHRVPDEYNPSEWIIYKLAVQPGQEKQSNDR---------------------------------------------IQKIVEQYEDSDHQKRVMEQLS--------DVSEKIPPPEM---HRANVFTQIFALSTRCGIDVWRAPQLTLAKVIQKILFGLFIGLLYLRTPYDAR-GIHNINGALFFLAGEYIYSTAYAIMFFLNNEFPLVAREYHDGLYNLWTYYFARCI-SLIPLFSTDGLILLFIVYWLIGLNTSVMQVIVASIITVLASQAASAFGIAMSCIFPTAQMTAVMASPPLVLFRLFGGLYGNTNTFPAAIRWLQWISMYRFAFEGLVVNQ 549          

HSP 2 Score: 65.4698 bits (158), Expect = 4.418e-44
Identity = 41/120 (34.17%), Postives = 73/120 (60.83%), Query Frame = 2
Query:  710 KIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYL--EGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +++L NV+G    G + A+MG +G+GK+++L++L  R + K L  EG + ++G         +SG+  Q+++ +GTLTV+E L   A LR++   +K  R  +VT+++ +L L    DSK
Sbjct:   48 RLLLKNVSGYAKSGELLALMGASGAGKTTLLNMLMCR-NLKGLSTEGTITVNGNEMAHKISSISGFAQQEELFVGTLTVKEYLMIQAKLRING--SKKLREDRVTDVLHQLKLWKCRDSK 164          
BLAST of ABC transporter domain-containing protein vs. Ensembl Celegans
Match: wht-1 (WHiTe (Drosophila) related ABC transporter [Source:UniProtKB/TrEMBL;Acc:A0A2K5ATT2])

HSP 1 Score: 166.392 bits (420), Expect = 1.846e-42
Identity = 138/512 (26.95%), Postives = 240/512 (46.88%), Query Frame = 1
Query: 1000 IRQGDKHY----QRVRI--------IRSC-----G*QELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKD-----QCY--TLKTFPNISCYVTGNVFLDRNGF 2463
            +R GD++Y    +++R+        ++ C     G    L+G+S GE+KR +   E++T P ++F DEPT+GLDAF A  V++ L+ L+ +G T+I++IHQP   +Y LF+   +MA G++IY G  G   +  F   GY    + NPAD  I                      R +AV++S    S                  +K+  K+    L+ D  +S+       +L A   +T  DT  + +    +  Y  S+  Q   L WR+ + ++R+P   +++L   L  AF  GIV+F   +  +        +F         +    + +   E PI + EN++G YR S+YF +K + ++    + P I++  I Y+M+GL  +   + F  L+ +L T    S+++ V+  F+   +A  + PI  V +M F G+F+   +I S+ +W   LS F++    L +NE        +C+  ++  F   SC   G+  L+   F
Sbjct:  168 LRMGDQYYSDHERQLRVEQVLTQMGLKKCADTVIGIPNQLKGLSCGEKKRLSFASEILTCPKILFCDEPTSGLDAFMAGHVVQALRSLADNGMTVIITIHQPSSHVYSLFNNVCLMACGRVIYLGP-GDQAVPLFEKCGYPCPAYYNPADHLI----------------------RTLAVIDSDRATS------------------MKTISKIRQGFLSTDLGQSVLAIGNANKLRAASFVTGSDTSEKTK-TFFNQDYNASFWTQFLALFWRSWLTVIRDPNLLSVRLLQILITAFITGIVFFQTPVTPATIISINGIMFNHIRNMNFMLQFPNVPVITAELPIVLRENANGVYRTSAYFLAKNIAELPQYIILP-ILYNTIVYWMSGLYPNFWNYCFASLVTILITNVAISISYAVATIFANTDVAMTILPIFVVPIMAFGGFFITFDAIPSYFKWLSSLSYFKYGYEALAINEWDSIKVIPECFNSSMTAFALDSCPKNGHQVLESIDF 636          

HSP 2 Score: 72.0182 bits (175), Expect = 1.332e-12
Identity = 42/118 (35.59%), Postives = 76/118 (64.41%), Query Frame = 2
Query:  716 ILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKY-LEGKVLIDGQPQPK-NFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTR-ITKNDRSAKVTNIIKELGLSAVADS 1057
            IL+NV+G+   G + AI+G +G+GK+++++VL  R      ++G +LIDG+   K   + MS +V Q D+ +GT+T RE+L+F A LR+  +  + ++R  +V  ++ ++GL   AD+
Sbjct:   82 ILHNVSGMAESGKLLAILGSSGAGKTTLMNVLTSRNLTNLDVQGSILIDGRRANKWKIREMSAFVQQHDMFVGTMTAREHLQFMARLRMGDQYYSDHERQLRVEQVLTQMGLKKCADT 199          
BLAST of ABC transporter domain-containing protein vs. Ensembl Fly
Match: w (gene:FBgn0003996 transcript:FBtr0070490)

HSP 1 Score: 189.119 bits (479), Expect = 2.536e-65
Identity = 140/472 (29.66%), Postives = 226/472 (47.88%), Query Frame = 1
Query: 1066 LRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKD------QCYTLKTFPNISCYVTGNVFLDRNGF 2463
            ++G+SGGERKR     E +TDP ++  DEPT+GLD+FTA SV++ L++LS+ GKT+IL+IHQP   +++LFD+  +MA+G++ + G    A +++F  +G     + NPADFY+ +L   V   +EI       SR  IA +  +           ++SKV R                  D E+ L  K L + L                 P    TY  +W  Q + + WR+ +++L+ P    ++L      A  +G+++ G ++           +F F            I +F  E P+F+ E  S  YR  +YF  K + ++ P+ +   +VF  I Y M GLR     FF    ++ L      S  + +S + S   +A  V P + +  ++F G+F+N  S+  +L+W  YLS FR+A  GL +N+  D       C    T  N +C  +G V L+   F
Sbjct:  238 VKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPSEA-VDFFSYVGAQCPTNYNPADFYVQVL--AVVPGREI------ESRDRIAKICDN----------FAISKVAR------------------DMEQLLATKNLEKPLEQ---------------PENGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAEL-PLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEPGEISC----TSSNTTCPSSGKVILETLNF 652          

HSP 2 Score: 81.2629 bits (199), Expect = 2.536e-65
Identity = 48/117 (41.03%), Postives = 73/117 (62.39%), Query Frame = 2
Query:  710 KIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLE----GKVLIDGQP-QPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLS 1042
            K +L NV GV  PG + A+MG +G+GK+++L+ LA R  P+ ++    G  L++GQP   K  +    YV QDD+ +G+LT RE+L F A +R+   +T   R A+V  +I+EL LS
Sbjct:  110 KHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFR-SPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLS 225          
BLAST of ABC transporter domain-containing protein vs. Ensembl Fly
Match: CG3164 (gene:FBgn0025683 transcript:FBtr0078155)

HSP 1 Score: 121.709 bits (304), Expect = 2.132e-44
Identity = 118/456 (25.88%), Postives = 213/456 (46.71%), Query Frame = 1
Query: 1063 LLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLN---------AYDVITEDDTDAEIR-PPSISIT-------------YATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGG 2361
            + R +SGG++KR +I +EL+++P ++F DEPT+GLD+ T    I  L+ L+  G+T+I +IHQP   ++++FD+   +A G+ +Y G S    + +   L      ++NPA + I++  GE  +    L   I   +R +    SS +Y+ +K     + KV   K+ L  +    +    Y+   +LN   L   +N         +  V T +  DA I    S++ T             Y TS  +Q   +  RT +   R+     ++L  +L   F +G +Y+ +  + +    N   LFF     +       I  F  E P+ + EN + +Y + SY+ +  + D+ P +    ++++ I Y+      +   F  F    LL +    SV   V A+ +V      + P++ V  ++FSG+F++  +I  +L+W  YLS  R+   G
Sbjct:  182 MTRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQG-STKQLVPFLSTLNLECPSYHNPASYVIEVSCGEHGDHTRKLVDAIDNGKRDV---RSSADYAGLKARN-DLVKVQNLKAILDKNDASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEEITSPERYPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKVLSNLGFLFFNMLFLMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADL-PFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAAMNVQN-GVFLAPVMSVPFLLFSGFFVSFDAIPVYLRWITYLSYIRYGFEG 630          

HSP 2 Score: 78.9518 bits (193), Expect = 2.132e-44
Identity = 46/135 (34.07%), Postives = 86/135 (63.70%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQ-PKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLS 1042
            ++FH+++Y+ K      ++S  K IL  V+G +  G + AIMGP+G+GKS++L++L+G K    +EG V ++G  +    F+ +S Y++QD+ + G LTV+E +  +  L+LS + +K ++ + + +I+  L LS
Sbjct:   47 LAFHNLTYRVKEG----NRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSS-IEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSLS 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Fly
Match: CG3164 (gene:FBgn0025683 transcript:FBtr0078153)

HSP 1 Score: 121.709 bits (304), Expect = 2.132e-44
Identity = 118/456 (25.88%), Postives = 213/456 (46.71%), Query Frame = 1
Query: 1063 LLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLN---------AYDVITEDDTDAEIR-PPSISIT-------------YATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGG 2361
            + R +SGG++KR +I +EL+++P ++F DEPT+GLD+ T    I  L+ L+  G+T+I +IHQP   ++++FD+   +A G+ +Y G S    + +   L      ++NPA + I++  GE  +    L   I   +R +    SS +Y+ +K     + KV   K+ L  +    +    Y+   +LN   L   +N         +  V T +  DA I    S++ T             Y TS  +Q   +  RT +   R+     ++L  +L   F +G +Y+ +  + +    N   LFF     +       I  F  E P+ + EN + +Y + SY+ +  + D+ P +    ++++ I Y+      +   F  F    LL +    SV   V A+ +V      + P++ V  ++FSG+F++  +I  +L+W  YLS  R+   G
Sbjct:  182 MTRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQG-STKQLVPFLSTLNLECPSYHNPASYVIEVSCGEHGDHTRKLVDAIDNGKRDV---RSSADYAGLKARN-DLVKVQNLKAILDKNDASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEEITSPERYPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKVLSNLGFLFFNMLFLMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADL-PFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAAMNVQN-GVFLAPVMSVPFLLFSGFFVSFDAIPVYLRWITYLSYIRYGFEG 630          

HSP 2 Score: 78.9518 bits (193), Expect = 2.132e-44
Identity = 46/135 (34.07%), Postives = 86/135 (63.70%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQ-PKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLS 1042
            ++FH+++Y+ K      ++S  K IL  V+G +  G + AIMGP+G+GKS++L++L+G K    +EG V ++G  +    F+ +S Y++QD+ + G LTV+E +  +  L+LS + +K ++ + + +I+  L LS
Sbjct:   47 LAFHNLTYRVKEG----NRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSS-IEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSLS 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Fly
Match: CG3164 (gene:FBgn0025683 transcript:FBtr0078154)

HSP 1 Score: 121.709 bits (304), Expect = 2.710e-44
Identity = 118/456 (25.88%), Postives = 213/456 (46.71%), Query Frame = 1
Query: 1063 LLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLN---------AYDVITEDDTDAEIR-PPSISIT-------------YATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGG 2361
            + R +SGG++KR +I +EL+++P ++F DEPT+GLD+ T    I  L+ L+  G+T+I +IHQP   ++++FD+   +A G+ +Y G S    + +   L      ++NPA + I++  GE  +    L   I   +R +    SS +Y+ +K     + KV   K+ L  +    +    Y+   +LN   L   +N         +  V T +  DA I    S++ T             Y TS  +Q   +  RT +   R+     ++L  +L   F +G +Y+ +  + +    N   LFF     +       I  F  E P+ + EN + +Y + SY+ +  + D+ P +    ++++ I Y+      +   F  F    LL +    SV   V A+ +V      + P++ V  ++FSG+F++  +I  +L+W  YLS  R+   G
Sbjct:  181 MTRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQG-STKQLVPFLSTLNLECPSYHNPASYVIEVSCGEHGDHTRKLVDAIDNGKRDV---RSSADYAGLKARN-DLVKVQNLKAILDKNDASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEEITSPERYPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKVLSNLGFLFFNMLFLMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADL-PFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAAMNVQN-GVFLAPVMSVPFLLFSGFFVSFDAIPVYLRWITYLSYIRYGFEG 629          

HSP 2 Score: 78.5666 bits (192), Expect = 2.710e-44
Identity = 46/135 (34.07%), Postives = 86/135 (63.70%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQ-PKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLS 1042
            ++FH+++Y+ K      ++S  K IL  V+G +  G + AIMGP+G+GKS++L++L+G K    +EG V ++G  +    F+ +S Y++QD+ + G LTV+E +  +  L+LS + +K ++ + + +I+  L LS
Sbjct:   46 LAFHNLTYRVKEG----NRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSS-IEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSLS 175          
BLAST of ABC transporter domain-containing protein vs. Ensembl Fly
Match: CG3164 (gene:FBgn0025683 transcript:FBtr0100379)

HSP 1 Score: 121.709 bits (304), Expect = 2.710e-44
Identity = 118/456 (25.88%), Postives = 213/456 (46.71%), Query Frame = 1
Query: 1063 LLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLN---------AYDVITEDDTDAEIR-PPSISIT-------------YATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGG 2361
            + R +SGG++KR +I +EL+++P ++F DEPT+GLD+ T    I  L+ L+  G+T+I +IHQP   ++++FD+   +A G+ +Y G S    + +   L      ++NPA + I++  GE  +    L   I   +R +    SS +Y+ +K     + KV   K+ L  +    +    Y+   +LN   L   +N         +  V T +  DA I    S++ T             Y TS  +Q   +  RT +   R+     ++L  +L   F +G +Y+ +  + +    N   LFF     +       I  F  E P+ + EN + +Y + SY+ +  + D+ P +    ++++ I Y+      +   F  F    LL +    SV   V A+ +V      + P++ V  ++FSG+F++  +I  +L+W  YLS  R+   G
Sbjct:  181 MTRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQG-STKQLVPFLSTLNLECPSYHNPASYVIEVSCGEHGDHTRKLVDAIDNGKRDV---RSSADYAGLKARN-DLVKVQNLKAILDKNDASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEEITSPERYPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKVLSNLGFLFFNMLFLMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADL-PFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAAMNVQN-GVFLAPVMSVPFLLFSGFFVSFDAIPVYLRWITYLSYIRYGFEG 629          

HSP 2 Score: 78.5666 bits (192), Expect = 2.710e-44
Identity = 46/135 (34.07%), Postives = 86/135 (63.70%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQ-PKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLS 1042
            ++FH+++Y+ K      ++S  K IL  V+G +  G + AIMGP+G+GKS++L++L+G K    +EG V ++G  +    F+ +S Y++QD+ + G LTV+E +  +  L+LS + +K ++ + + +I+  L LS
Sbjct:   46 LAFHNLTYRVKEG----NRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSS-IEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSLS 175          
BLAST of ABC transporter domain-containing protein vs. Ensembl Zebrafish
Match: abcg2d (ATP-binding cassette, sub-family G (WHITE), member 2d [Source:ZFIN;Acc:ZDB-GENE-050517-38])

HSP 1 Score: 285.419 bits (729), Expect = 2.508e-126
Identity = 192/543 (35.36%), Postives = 290/543 (53.41%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKV---GRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPI--FIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMM----------VFSGYFMNISSIFSWLQWCQYLSAFRFALGG-------LCVNEMKDQCYTLKTFPNIS----------------CYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            +++RG+SGGERKR +IGMELI DPSV+FLDEPTTGLDA TA SV+  L+R++  G+TII+SIHQP++SIY+LFD  T++A GK +YHG +  A L+YF N+GY  E HNNPADF++D++NG                                     SV+K+   G  + D+ +  +  +E    +   S +F    R    + + T+D + + +     SITY++S+  Q++W+ WRT  NL+ NPQTS  QL V    A  +G +++G+K     DDQ+                       I+ R +  F HE +SGYYRVS +F SK+L D++  +  P+++F  + YFM GL+  A AFF F L ++L +    ++A  +SA  SV  +AN++  + ++FMM          +FSG  +N+ SI  WL W +YLS  R+ L          C +E  +Q   +  F  +S                   TG   L   G  Y   W LW+N + L +++L FLI+ Y++LR ++K+ 
Sbjct:  184 QIIRGISGGERKRTSIGMELIIDPSVLFLDEPTTGLDASTAHSVLLLLKRMAGQGRTIIMSIHQPRFSIYRLFDSLTLLANGKQVYHGPAQDA-LDYFSNIGYACEAHNNPADFFLDVINGS------------------------------------SVTKIQNNGDAECDVSAVSRQSVEDQLMEKYRSCSFARAVRAELDHIIQTKDSSSSSVAAECHSITYSSSFCQQLRWVLWRTFWNLMLNPQTSVAQLAVTTLMAAIVGAIFYGVK-----DDQSG----------------------IQNRRVDHFYHEYTSGYYRVSVFFLSKILSDIITQRTIPSVLFSCVVYFMIGLKPTASAFFIFMLTVILVSCTAAAMAMAISADQSVVAVANILMTVSFIFMMASSHLVTTQNIFSGLLVNLKSIMDWLSWLKYLSIPRYGLEEHPGFQLMRCFDEYLEQALEINEFVGLSFCGNVSESLASPAAHVLMCTGEQHLTFQGIDY-SSWGLWQNHVALTVMTLIFLIIAYIKLRFISKFS 661          

HSP 2 Score: 189.119 bits (479), Expect = 2.508e-126
Identity = 91/144 (63.19%), Postives = 115/144 (79.86%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKKYPWSK--SVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            G+ +SFHSI Y+ + K  P  +  +V K IL ++NG+M PG+NAI+GPTGSGKSS LDVLAGRKDP  L G+VL++G  QP NFKC+SGYVVQDDIVMGTLTVRENL FSAALRLS+ ++  ++ A+V ++I ELGL+ VADSK
Sbjct:   37 GATVSFHSIRYRVEQKTGPVCRRTTVQKEILLDLNGIMRPGLNAILGPTGSGKSSFLDVLAGRKDPAGLSGEVLVNGALQPANFKCLSGYVVQDDIVMGTLTVRENLSFSAALRLSSHVSPREKEARVNHLISELGLNKVADSK 180          
BLAST of ABC transporter domain-containing protein vs. Ensembl Zebrafish
Match: abcg2d (ATP-binding cassette, sub-family G (WHITE), member 2d [Source:ZFIN;Acc:ZDB-GENE-050517-38])

HSP 1 Score: 276.944 bits (707), Expect = 7.050e-124
Identity = 177/483 (36.65%), Postives = 264/483 (54.66%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKV---GRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPI--FIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMM----------VFSGYFMNISSIFSWLQWCQYLSAFRFALGG-------LCVNEMKDQCYTLKTFPNISCYVTGNV 2442
            +++RG+SGGERKR +IGMELI DPSV+FLDEPTTGLDA TA SV+  L+R++  G+TII+SIHQP++SIY+LFD  T++A GK +YHG +  A L+YF N+GY  E HNNPADF++D++NG                                     SV+K+   G  + D+ +  +  +E    +   S +F    R    + + T+D + + +     SITY++S+  Q++W+ WRT  NL+ NPQTS  QL V    A  +G +++G+K     DDQ+                       I+ R +  F HE +SGYYRVS +F SK+L D++  +  P+++F  + YFM GL+  A AFF F L ++L +    ++A  +SA  SV  +AN++  + ++FMM          +FSG  +N+ SI  WL W +YLS  R+ L          C +E  +Q   +  F  +S    GNV
Sbjct:  184 QIIRGISGGERKRTSIGMELIIDPSVLFLDEPTTGLDASTAHSVLLLLKRMAGQGRTIIMSIHQPRFSIYRLFDSLTLLANGKQVYHGPAQDA-LDYFSNIGYACEAHNNPADFFLDVINGS------------------------------------SVTKIQNNGDAECDVSAVSRQSVEDQLMEKYRSCSFARAVRAELDHIIQTKDSSSSSVAAECHSITYSSSFCQQLRWVLWRTFWNLMLNPQTSVAQLAVTTLMAAIVGAIFYGVK-----DDQSG----------------------IQNRRVDHFYHEYTSGYYRVSVFFLSKILSDIITQRTIPSVLFSCVVYFMIGLKPTASAFFIFMLTVILVSCTAAAMAMAISADQSVVAVANILMTVSFIFMMASSHLVTTQNIFSGLLVNLKSIMDWLSWLKYLSIPRYGLEEHPGFQLMRCFDEYLEQALEINEFVGLS--FCGNV 600          

HSP 2 Score: 189.119 bits (479), Expect = 7.050e-124
Identity = 91/144 (63.19%), Postives = 115/144 (79.86%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKKYPWSK--SVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            G+ +SFHSI Y+ + K  P  +  +V K IL ++NG+M PG+NAI+GPTGSGKSS LDVLAGRKDP  L G+VL++G  QP NFKC+SGYVVQDDIVMGTLTVRENL FSAALRLS+ ++  ++ A+V ++I ELGL+ VADSK
Sbjct:   37 GATVSFHSIRYRVEQKTGPVCRRTTVQKEILLDLNGIMRPGLNAILGPTGSGKSSFLDVLAGRKDPAGLSGEVLVNGALQPANFKCLSGYVVQDDIVMGTLTVRENLSFSAALRLSSHVSPREKEARVNHLISELGLNKVADSK 180          
BLAST of ABC transporter domain-containing protein vs. Ensembl Zebrafish
Match: abcg2b (ATP-binding cassette, sub-family G (WHITE), member 2b [Source:ZFIN;Acc:ZDB-GENE-050517-36])

HSP 1 Score: 330.872 bits (847), Expect = 1.151e-123
Identity = 203/505 (40.20%), Postives = 300/505 (59.41%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            E +RGVSGGERKRC+IGMELIT P+++FLDEPTTGLD+ TA S+I  L RLSR G+TII SIHQP+YSI++LFD  T+M KG+ +Y G +G A ++YF +LGY  +  NNPADF++DI NGE                                             + + ++K      L   + ES     +  +L      ++  ++A+ + PS    Y TS+S Q+K +CWRT +N++RNPQTS  Q+ + + FA  +G+VY+ + +      QNR G FFF  + +VF NL A+E+FI ER IF+HENS GYYR S YF SK+  D++P ++ P ++F  I+Y+M GL     +F  F L + L + AG S+AF VSAS S F +AN++  + +VFMMVF G+ +N++S+ +WL W +++S F++ L  + +NEMK          + +  + G ++L+  G  Y   W  W+N + L  I L  +   Y+QLRR+N++K
Sbjct:  173 EFIRGVSGGERKRCSIGMELITSPTLLFLDEPTTGLDSNTANSIIALLHRLSRGGRTIIFSIHQPRYSIFRLFDYLTLMHKGETVYAGPAGKA-IDYFQSLGYERDAFNNPADFFLDITNGETA-------------------------------------------TSMPTEKS-----LAELYRESQFCTAVDEELKCITGPSDSLSEAKSKAPS----YVTSFSYQLKVVCWRTGLNVVRNPQTSYAQIAMNILFALLIGLVYYQMPLTLPEALQNRIGAFFFLIINMVFGNLSAVELFINERAIFVHENSGGYYRTSVYFLSKVFVDLLPNRIVPILIFSSISYYMMGLNPAFTSFLCFALTMSLVSLAGVSLAFLVSASVSTFAMANILVVLPFVFMMVFGGFLVNLNSMLNWLSWLKWISIFKYGLDAVTINEMKGL-----VLYSGNATLPGELYLESQGIDY-SVWGFWQNEVALLGIVLVCMTFAYIQLRRINRWK 618          

HSP 2 Score: 134.42 bits (337), Expect = 1.151e-123
Identity = 76/152 (50.00%), Postives = 104/152 (68.42%), Query Frame = 2
Query:  614 HRKTPTKGSIISFHSISYKAK-SKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLE-GKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRL-STRITKNDRSAKVTNIIKELGLSAVADSK 1060
            H K P  G I+++ +I Y  + S+     K+  + IL NV+G+M  G+NAIMG TGSGK+S+LDV+AGRKDP+ L  G+VL+D +    + + MS YVVQDD++MGTLTVRENL FS  LRL   + +  D+  KV +II+ELGL   AD+K
Sbjct:   20 HVKVP--GPILTYQNIHYCIRESRGLCCKKAPERDILKNVSGIMKTGLNAIMGATGSGKTSLLDVMAGRKDPRGLRSGQVLVDNKLVTSDLRLMSAYVVQDDVLMGTLTVRENLLFSGNLRLPREQFSSADKKKKVESIIEELGLEDCADTK 169          
BLAST of ABC transporter domain-containing protein vs. Ensembl Zebrafish
Match: abcg2b (ATP-binding cassette, sub-family G (WHITE), member 2b [Source:ZFIN;Acc:ZDB-GENE-050517-36])

HSP 1 Score: 330.872 bits (847), Expect = 1.151e-123
Identity = 203/505 (40.20%), Postives = 300/505 (59.41%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            E +RGVSGGERKRC+IGMELIT P+++FLDEPTTGLD+ TA S+I  L RLSR G+TII SIHQP+YSI++LFD  T+M KG+ +Y G +G A ++YF +LGY  +  NNPADF++DI NGE                                             + + ++K      L   + ES     +  +L      ++  ++A+ + PS    Y TS+S Q+K +CWRT +N++RNPQTS  Q+ + + FA  +G+VY+ + +      QNR G FFF  + +VF NL A+E+FI ER IF+HENS GYYR S YF SK+  D++P ++ P ++F  I+Y+M GL     +F  F L + L + AG S+AF VSAS S F +AN++  + +VFMMVF G+ +N++S+ +WL W +++S F++ L  + +NEMK          + +  + G ++L+  G  Y   W  W+N + L  I L  +   Y+QLRR+N++K
Sbjct:  173 EFIRGVSGGERKRCSIGMELITSPTLLFLDEPTTGLDSNTANSIIALLHRLSRGGRTIIFSIHQPRYSIFRLFDYLTLMHKGETVYAGPAGKA-IDYFQSLGYERDAFNNPADFFLDITNGETA-------------------------------------------TSMPTEKS-----LAELYRESQFCTAVDEELKCITGPSDSLSEAKSKAPS----YVTSFSYQLKVVCWRTGLNVVRNPQTSYAQIAMNILFALLIGLVYYQMPLTLPEALQNRIGAFFFLIINMVFGNLSAVELFINERAIFVHENSGGYYRTSVYFLSKVFVDLLPNRIVPILIFSSISYYMMGLNPAFTSFLCFALTMSLVSLAGVSLAFLVSASVSTFAMANILVVLPFVFMMVFGGFLVNLNSMLNWLSWLKWISIFKYGLDAVTINEMKGL-----VLYSGNATLPGELYLESQGIDY-SVWGFWQNEVALLGIVLVCMTFAYIQLRRINRWK 618          

HSP 2 Score: 134.42 bits (337), Expect = 1.151e-123
Identity = 76/152 (50.00%), Postives = 104/152 (68.42%), Query Frame = 2
Query:  614 HRKTPTKGSIISFHSISYKAK-SKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLE-GKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRL-STRITKNDRSAKVTNIIKELGLSAVADSK 1060
            H K P  G I+++ +I Y  + S+     K+  + IL NV+G+M  G+NAIMG TGSGK+S+LDV+AGRKDP+ L  G+VL+D +    + + MS YVVQDD++MGTLTVRENL FS  LRL   + +  D+  KV +II+ELGL   AD+K
Sbjct:   20 HVKVP--GPILTYQNIHYCIRESRGLCCKKAPERDILKNVSGIMKTGLNAIMGATGSGKTSLLDVMAGRKDPRGLRSGQVLVDNKLVTSDLRLMSAYVVQDDVLMGTLTVRENLLFSGNLRLPREQFSSADKKKKVESIIEELGLEDCADTK 169          
BLAST of ABC transporter domain-containing protein vs. Ensembl Zebrafish
Match: abcg2c (ATP-binding cassette, sub-family G (WHITE), member 2c [Source:ZFIN;Acc:ZDB-GENE-050517-37])

HSP 1 Score: 323.168 bits (827), Expect = 1.417e-123
Identity = 211/503 (41.95%), Postives = 302/503 (60.04%), Query Frame = 1
Query: 1066 LRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            LRGVSGGE+KRC+IGMELIT PS++FLDEPTTGLDA TA S+++ LQ +S+ GKT+I SIHQP+YSI++ FD  T+M KG+IIY G +  A + YF +LGY  EP NNPADF++D+ NG ++  K         S  +I+   SS E                   D ++   V+  K  Y       F +L+ +L        D  D E+      I YAT +  Q+  +  RT  N+LRNPQTS  QL + +FF   +G++Y+ +        QNR G FFF  + +VF NL A+E+F+ ER +FIHENSSG+YR S+YF SK+  D++P ++ P  +F  I YFM GL+ +  AFF + + + + + +  S+AF VSAS   F +AN++  + YVFMMVF G+ +N++S+ S L W ++ S FR+    L +NE+KDQ +T     N++  VTG+++LD         W  W+N + L  I    LIL YVQL R+N++K
Sbjct:  176 LRGVSGGEKKRCSIGMELITSPSLLFLDEPTTGLDANTANSIMELLQNISKKGKTVIFSIHQPRYSIFRQFDHLTLMNKGEIIYAGAADKAII-YFEDLGYKCEPFNNPADFFLDVTNGTIRPHK---------SSNNISEKCSSSE----------------EMVDNENPLAVMYRKSPY-------FTKLKDRLTE----ISDGLDPEVTKGD-KIGYATPFYYQLLLVSGRTIRNILRNPQTSYAQLFLNIFFGILVGLIYYQIPHTLPEALQNRTGAFFFLVINMVFGNLSAVELFVSERELFIHENSSGFYRTSAYFLSKVFADLIPNRILPVFIFSAIPYFMMGLKPEVEAFFLYCVTMSMVSLSAVSLAFLVSASVGSFAMANILIALPYVFMMVFGGFLVNLNSMLSGLSWLKWASIFRYGYNALAINELKDQVFT----DNLT-RVTGDMYLDHQEIDR-SAWGFWENQVALAGIMFVCLILAYVQLCRINRWK 634          

HSP 2 Score: 142.124 bits (357), Expect = 1.417e-123
Identity = 77/147 (52.38%), Postives = 106/147 (72.11%), Query Frame = 2
Query:  629 TKGSIISFHSISYKAKSKKYPWS-KSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLE-GKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTR-ITKNDRSAKVTNIIKELGLSAVADSK 1060
            T G  ++FH I Y+ K +   +S +   K IL +V+G+M PG+NAIMGPTGSGK+S+LDV+AGRKDPK L+ G+VL+D      + +  S YVVQ+DI+MGTLTVRENL FSA LRLS +  + +D+  +V ++I+ELGL   AD+K
Sbjct:   24 TPGPTVTFHQIRYRIKERLGMFSCQWREKDILKDVSGIMNPGMNAIMGPTGSGKTSLLDVIAGRKDPKGLKSGQVLVDNTIVTSDLRLCSAYVVQNDILMGTLTVRENLAFSANLRLSLKEYSSSDKEMRVNSVIQELGLKDCADTK 170          
BLAST of ABC transporter domain-containing protein vs. Ensembl Xenopus
Match: cib1 (calcium and integrin binding 1 [Source:Xenbase;Acc:XB-GENE-970951])

HSP 1 Score: 325.865 bits (834), Expect = 4.349e-138
Identity = 198/486 (40.74%), Postives = 286/486 (58.85%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKT-----FPNISCYVTGNVFLDRNGFYYLQPWDLWKN 2496
            + +RGVSGGERKR NIGMELITDP ++FLDEPTTGLDA TA +V+  L+R+SR GKTII SIHQP+YSI++LFD  T++A G++++HG S  A L+YF  LGY  E HNNPADF++DI+NG+            + +   +  +E   E  EV                  +  K ++E L+  +  +  + E + +L    +  +  ++   R     ITY TS+ +Q+KW+C R+  NLLRNPQ S  Q+ V L  A  +G ++FG+K + S   QNR G  FF      F ++ AIE+FI E+ IFIHE  SGYYR+S+YFF+KL  D++P++  P+I+F  + YFM G +  AGAFF     L++      S+A  V+A   V  +AN++  I +VFM++FSG  +N++S+  W+ W +Y S  R+ L  L +NE  +   C  L T     F  +S   TG  +L   G  +   W LW+N
Sbjct:  180 QFIRGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLLLKRMSRQGKTIIFSIHQPRYSIFRLFDSLTLLAGGRLLFHGPSRDA-LDYFTGLGYECESHNNPADFFLDIINGD----------STAVALNKLEDVELENEQKEVN----------------DNGSKTVVENLSEQFCTTSYYLETKAELEKMSLGKKIKSNFFAR----QITYNTSFLHQLKWVCKRSFKNLLRNPQASIAQVMVTLVLALIVGAIFFGVKEDVS-GIQNRVGSLFFVTTNQCFSSVSAIELFIVEKKIFIHEYISGYYRLSAYFFAKLFTDLLPMRTLPSIIFTSVLYFMIGFKATAGAFFTMMFTLMMIAYTAASMALAVAAGQDVVAVANLLMTICFVFMIIFSGLLVNLTSVMDWISWLKYFSIPRYGLTALQINEFTNLNFCNGLNTTIQVIFGLLSFRCTGEEYLTVQGIDF-STWGLWQN 632          

HSP 2 Score: 188.348 bits (477), Expect = 4.349e-138
Identity = 89/149 (59.73%), Postives = 119/149 (79.87%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K    G+++SF++I+YK K K      + VT ++ILN+VNG+M PG+NAI+GPTGSGKSS+LDVLA RKDP  L G+VL+DG+PQP NFKC+SGYVVQDD+VMGTL++RENL+FSAALRL   + + ++  ++  +IKELGL+ VADSK
Sbjct:   28 KKTLSGAVLSFYNINYKVKVKSGLICRRKVTERVILNDVNGIMRPGLNAILGPTGSGKSSLLDVLAARKDPNGLSGQVLVDGEPQPSNFKCLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERINQVIKELGLTKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Xenopus
Match: cib1 (calcium and integrin binding 1 [Source:Xenbase;Acc:XB-GENE-970951])

HSP 1 Score: 325.094 bits (832), Expect = 5.867e-138
Identity = 198/486 (40.74%), Postives = 291/486 (59.88%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKT-----FPNISCYVTGNVFLDRNGFYYLQPWDLWKN 2496
            + +RGVSGGERKR NIGMELITDP ++FLDEPTTGLDA TA +V+  L+R+SR GKTII SIHQP+YSI++LFD  T++A G++++HG S  A L+YF  LGY  E HNNPADF++DI+NG+            + +   +  +E+  + +E K +           +D  +  K ++E L+  +  +  + E + +L    +  +  ++   R     ITY TS+ +Q+KW+C R+  NLLRNPQ S  Q+ V L  A  +G ++FG+K + S   QNR G  FF      F ++ AIE+FI E+ IFIHE  SGYYR+S+YFF+KL  D++P++  P+I+F  + YFM G +  AGAFF     L++      S+A  V+A   V  +AN++  I +VFM++FSG  +N++S+  W+ W +Y S  R+ L  L +NE  +   C  L T     F  +S   TG  +L   G  +   W LW+N
Sbjct:  179 QFIRGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLLLKRMSRQGKTIIFSIHQPRYSIFRLFDSLTLLAGGRLLFHGPSRDA-LDYFTGLGYECESHNNPADFFLDIINGD----------STAVALNKLEDVEAPCQQNEQKEV-----------ND--NGSKTVVENLSEQFCTTSYYLETKAELEKMSLGKKIKSNFFAR----QITYNTSFLHQLKWVCKRSFKNLLRNPQASIAQVMVTLVLALIVGAIFFGVKEDVS-GIQNRVGSLFFVTTNQCFSSVSAIELFIVEKKIFIHEYISGYYRLSAYFFAKLFTDLLPMRTLPSIIFTSVLYFMIGFKATAGAFFTMMFTLMMIAYTAASMALAVAAGQDVVAVANLLMTICFVFMIIFSGLLVNLTSVMDWISWLKYFSIPRYGLTALQINEFTNLNFCNGLNTTIQVIFGLLSFRCTGEEYLTVQGIDF-STWGLWQN 634          

HSP 2 Score: 188.348 bits (477), Expect = 5.867e-138
Identity = 89/149 (59.73%), Postives = 119/149 (79.87%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K    G+++SF++I+YK K K      + VT ++ILN+VNG+M PG+NAI+GPTGSGKSS+LDVLA RKDP  L G+VL+DG+PQP NFKC+SGYVVQDD+VMGTL++RENL+FSAALRL   + + ++  ++  +IKELGL+ VADSK
Sbjct:   27 KKTLSGAVLSFYNINYKVKVKSGLICRRKVTERVILNDVNGIMRPGLNAILGPTGSGKSSLLDVLAARKDPNGLSGQVLVDGEPQPSNFKCLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERINQVIKELGLTKVADSK 175          
BLAST of ABC transporter domain-containing protein vs. Ensembl Xenopus
Match: cib1 (calcium and integrin binding 1 [Source:Xenbase;Acc:XB-GENE-970951])

HSP 1 Score: 320.472 bits (820), Expect = 1.997e-136
Identity = 200/487 (41.07%), Postives = 286/487 (58.73%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLES-SGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKT-----FPNISCYVTGNVFLDRNGFYYLQPWDLWKN 2496
            + +RGVSGGERKR NIGMELITDP ++FLDEPTTGLDA TA +V+  L+R+SR GKTII SIHQP+YSI++LFD  T++A G++++HG S  A L+YF  LGY  E HNNPADF++DI+NG+           ++ ++     LES   + + +++   + S     K++L        EK++   +   NF    RQ                      ITY TS+ +Q+KW+C R+  NLLRNPQ S  Q+ V L  A  +G ++FG+K + S   QNR G  FF      F ++ AIE+FI E+ IFIHE  SGYYR+S+YFF+KL  D++P++  P+I+F  + YFM G +  AGAFF     L++      S+A  V+A   V  +AN++  I +VFM++FSG  +N++S+  W+ W +Y S  R+ L  L +NE  +   C  L T     F  +S   TG  +L   G  +   W LW+N
Sbjct:  180 QFIRGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLLLKRMSRQGKTIIFSIHQPRYSIFRLFDSLTLLAGGRLLFHGPSRDA-LDYFTGLGYECESHNNPADFFLDIINGD--------STAVALNKLEDVELESFLHQSTNLQKQFCTTSYYLETKAEL--------EKMSLGKKIKSNF--FARQ----------------------ITYNTSFLHQLKWVCKRSFKNLLRNPQASIAQVMVTLVLALIVGAIFFGVKEDVS-GIQNRVGSLFFVTTNQCFSSVSAIELFIVEKKIFIHEYISGYYRLSAYFFAKLFTDLLPMRTLPSIIFTSVLYFMIGFKATAGAFFTMMFTLMMIAYTAASMALAVAAGQDVVAVANLLMTICFVFMIIFSGLLVNLTSVMDWISWLKYFSIPRYGLTALQINEFTNLNFCNGLNTTIQVIFGLLSFRCTGEEYLTVQGIDF-STWGLWQN 623          

HSP 2 Score: 188.348 bits (477), Expect = 1.997e-136
Identity = 89/149 (59.73%), Postives = 119/149 (79.87%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K    G+++SF++I+YK K K      + VT ++ILN+VNG+M PG+NAI+GPTGSGKSS+LDVLA RKDP  L G+VL+DG+PQP NFKC+SGYVVQDD+VMGTL++RENL+FSAALRL   + + ++  ++  +IKELGL+ VADSK
Sbjct:   28 KKTLSGAVLSFYNINYKVKVKSGLICRRKVTERVILNDVNGIMRPGLNAILGPTGSGKSSLLDVLAARKDPNGLSGQVLVDGEPQPSNFKCLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERINQVIKELGLTKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Xenopus
Match: cib1 (calcium and integrin binding 1 [Source:Xenbase;Acc:XB-GENE-970951])

HSP 1 Score: 318.161 bits (814), Expect = 7.878e-136
Identity = 194/490 (39.59%), Postives = 287/490 (58.57%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCY------TLKTFPNIS-----CYVTGNVFLDRNGFYYLQPWDLWKN 2496
            + +RGVSGGERKR NIGMELITDP ++FLDEPTTGLDA TA +V+  L+R+SR GKTII SIHQP+YSI++LFD  T++A G++++HG S  A L+YF  LGY  E HNNPADF++DI+NG+                                   ++++K+    +D  +  K ++E L+  +  +  + E + +L    +  +  ++   R     ITY TS+ +Q+KW+C R+  NLLRNPQ S  Q+ V L  A  +G ++FG+K + S   QNR G  FF      F ++ AIE+FI E+ IFIHE  SGYYR+S+YFF+KL  D++P++  P+I+F  + YFM G +  AGAFF     L++      S+A  V+A   V  +AN++  I +VFM++FSG  +N++S+  W+ W +Y S  R+ L  L +NE  +  +      T++  PN +        TG  +L   G  +   W LW+N
Sbjct:  158 QFIRGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLLLKRMSRQGKTIIFSIHQPRYSIFRLFDSLTLLAGGRLLFHGPSRDA-LDYFTGLGYECESHNNPADFFLDIINGD--------------------------------STAVALNKLEDEVND--NGSKTVVENLSEQFCTTSYYLETKAELEKMSLGKKIKSNFFAR----QITYNTSFLHQLKWVCKRSFKNLLRNPQASIAQVMVTLVLALIVGAIFFGVKEDVS-GIQNRVGSLFFVTTNQCFSSVSAIELFIVEKKIFIHEYISGYYRLSAYFFAKLFTDLLPMRTLPSIIFTSVLYFMIGFKATAGAFFTMMFTLMMIAYTAASMALAVAAGQDVVAVANLLMTICFVFMIIFSGLLVNLTSVMDWISWLKYFSIPRYGLTALQINEFTNLNFCNGLNTTIQGNPNCTGSSPFGTCTGEEYLTVQGIDF-STWGLWQN 606          

HSP 2 Score: 188.348 bits (477), Expect = 7.878e-136
Identity = 89/149 (59.73%), Postives = 119/149 (79.87%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K    G+++SF++I+YK K K      + VT ++ILN+VNG+M PG+NAI+GPTGSGKSS+LDVLA RKDP  L G+VL+DG+PQP NFKC+SGYVVQDD+VMGTL++RENL+FSAALRL   + + ++  ++  +IKELGL+ VADSK
Sbjct:    6 KKTLSGAVLSFYNINYKVKVKSGLICRRKVTERVILNDVNGIMRPGLNAILGPTGSGKSSLLDVLAARKDPNGLSGQVLVDGEPQPSNFKCLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERINQVIKELGLTKVADSK 154          
BLAST of ABC transporter domain-containing protein vs. Ensembl Xenopus
Match: cib1 (calcium and integrin binding 1 [Source:Xenbase;Acc:XB-GENE-970951])

HSP 1 Score: 316.62 bits (810), Expect = 4.299e-135
Identity = 198/492 (40.24%), Postives = 285/492 (57.93%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNE--KEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCY------TLKTFPNIS-----CYVTGNVFLDRNGFYYLQPWDLWKN 2496
            + +RGVSGGERKR NIGMELITDP ++FLDEPTTGLDA TA +V+  L+R+SR GKTII SIHQP+YSI++LFD  T++A G++++HG S  A L+YF  LGY  E HNNPADF++DI+NG+       ++ D ++ Y  +         +Y  +     + S     K++L        EK++   +   NF    RQ                      ITY TS+ +Q+KW+C R+  NLLRNPQ S  Q+ V L  A  +G ++FG+K + S   QNR G  FF      F ++ AIE+FI E+ IFIHE  SGYYR+S+YFF+KL  D++P++  P+I+F  + YFM G +  AGAFF     L++      S+A  V+A   V  +AN++  I +VFM++FSG  +N++S+  W+ W +Y S  R+ L  L +NE  +  +      T++  PN +        TG  +L   G  +   W LW+N
Sbjct:  179 QFIRGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLLLKRMSRQGKTIIFSIHQPRYSIFRLFDSLTLLAGGRLLFHGPSRDA-LDYFTGLGYECESHNNPADFFLDIINGDSTAVALNKLEDVELVYPGK---------QYINLSEQFCTTSYYLETKAEL--------EKMSLGKKIKSNF--FARQ----------------------ITYNTSFLHQLKWVCKRSFKNLLRNPQASIAQVMVTLVLALIVGAIFFGVKEDVS-GIQNRVGSLFFVTTNQCFSSVSAIELFIVEKKIFIHEYISGYYRLSAYFFAKLFTDLLPMRTLPSIIFTSVLYFMIGFKATAGAFFTMMFTLMMIAYTAASMALAVAAGQDVVAVANLLMTICFVFMIIFSGLLVNLTSVMDWISWLKYFSIPRYGLTALQINEFTNLNFCNGLNTTIQGNPNCTGSSPFGTCTGEEYLTVQGIDF-STWGLWQN 626          

HSP 2 Score: 187.578 bits (475), Expect = 4.299e-135
Identity = 89/149 (59.73%), Postives = 119/149 (79.87%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K    G+++SF++I+YK K K      + VT ++ILN+VNG+M PG+NAI+GPTGSGKSS+LDVLA RKDP  L G+VL+DG+PQP NFKC+SGYVVQDD+VMGTL++RENL+FSAALRL   + + ++  ++  +IKELGL+ VADSK
Sbjct:   27 KKTLSGAVLSFYNINYKVKVKSGLICRRKVTERVILNDVNGIMRPGLNAILGPTGSGKSSLLDVLAARKDPNGLSGQVLVDGEPQPSNFKCLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERINQVIKELGLTKVADSK 175          
BLAST of ABC transporter domain-containing protein vs. Ensembl Mouse
Match: Abcg2 (ATP binding cassette subfamily G member 2 (Junior blood group) [Source:MGI Symbol;Acc:MGI:1347061])

HSP 1 Score: 323.553 bits (828), Expect = 6.715e-138
Identity = 199/511 (38.94%), Postives = 295/511 (57.73%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISCY-----VTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RG+SGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A GK+++HG +  A L YF + GYH EP+NNPADF++D++NG+  +   +L+++   +  +     S GE                         K +IE L+  +  S  + E + +L+      E    +  + P     Y TS+ +Q++W+  R+  NLL NPQ S  QL V +     +G +YF LK +A+   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYFF K++ D++P++  P+++F  I YFM GL+    AFF     L++      S+A  ++   SV  +A ++  I +VFMM+FSG  +N+ +I  WL W QY S  R+    L  NE   Q  C       N +C       TGN +L   G   L PW LWKN + L  + + FL + Y++L  + KY
Sbjct:  180 QFIRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLVFHGPAQKA-LEYFASAGYHCEPYNNPADFFLDVINGD--SSAVMLNREEQDNEANKTEEPSKGE-------------------------KPVIENLSEFYINSAIYGETKAELDQLPGAQEKKGTSAFKEP----VYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGAIYFDLKYDAA-GMQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKVMSDLLPMRFLPSVIFTCILYFMLGLKKTVDAFFIMMFTLIMVAYTASSMALAIATGQSVVSVATLLMTIAFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQYNEFLGQEFCPGFNVTDNSTCVNSYAICTGNEYLINQGI-ELSPWGLWKNHVALACMIIIFLTIAYLKLLFLKKY 656          

HSP 2 Score: 189.504 bits (480), Expect = 6.715e-138
Identity = 91/148 (61.49%), Postives = 117/148 (79.05%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +T  +G ++SFH I+Y+ K K  +   K+V K IL+++NG+M PG+NAI+GPTG GKSS+LDVLA RKDPK L G VLI+G PQP +FKC SGYVVQDD+VMGTLTVRENL+FSAALRL T +  ++++ ++  IIKELGL  VADSK
Sbjct:   29 RTLAEGDVLSFHHITYRVKVKSGFLVRKTVEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPKGLSGDVLINGAPQPAHFKCCSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMKNHEKNERINTIIKELGLEKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Mouse
Match: Abcg2 (ATP binding cassette subfamily G member 2 (Junior blood group) [Source:MGI Symbol;Acc:MGI:1347061])

HSP 1 Score: 323.553 bits (828), Expect = 6.715e-138
Identity = 199/511 (38.94%), Postives = 295/511 (57.73%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISCY-----VTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RG+SGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A GK+++HG +  A L YF + GYH EP+NNPADF++D++NG+  +   +L+++   +  +     S GE                         K +IE L+  +  S  + E + +L+      E    +  + P     Y TS+ +Q++W+  R+  NLL NPQ S  QL V +     +G +YF LK +A+   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYFF K++ D++P++  P+++F  I YFM GL+    AFF     L++      S+A  ++   SV  +A ++  I +VFMM+FSG  +N+ +I  WL W QY S  R+    L  NE   Q  C       N +C       TGN +L   G   L PW LWKN + L  + + FL + Y++L  + KY
Sbjct:  180 QFIRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLVFHGPAQKA-LEYFASAGYHCEPYNNPADFFLDVINGD--SSAVMLNREEQDNEANKTEEPSKGE-------------------------KPVIENLSEFYINSAIYGETKAELDQLPGAQEKKGTSAFKEP----VYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGAIYFDLKYDAA-GMQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKVMSDLLPMRFLPSVIFTCILYFMLGLKKTVDAFFIMMFTLIMVAYTASSMALAIATGQSVVSVATLLMTIAFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQYNEFLGQEFCPGFNVTDNSTCVNSYAICTGNEYLINQGI-ELSPWGLWKNHVALACMIIIFLTIAYLKLLFLKKY 656          

HSP 2 Score: 189.504 bits (480), Expect = 6.715e-138
Identity = 91/148 (61.49%), Postives = 117/148 (79.05%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +T  +G ++SFH I+Y+ K K  +   K+V K IL+++NG+M PG+NAI+GPTG GKSS+LDVLA RKDPK L G VLI+G PQP +FKC SGYVVQDD+VMGTLTVRENL+FSAALRL T +  ++++ ++  IIKELGL  VADSK
Sbjct:   29 RTLAEGDVLSFHHITYRVKVKSGFLVRKTVEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPKGLSGDVLINGAPQPAHFKCCSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMKNHEKNERINTIIKELGLEKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Mouse
Match: Abcg2 (ATP binding cassette subfamily G member 2 (Junior blood group) [Source:MGI Symbol;Acc:MGI:1347061])

HSP 1 Score: 276.174 bits (705), Expect = 6.623e-124
Identity = 162/405 (40.00%), Postives = 244/405 (60.25%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVF 2274
            + +RG+SGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A GK+++HG +  A L YF + GYH EP+NNPADF++D++NG+  +   +L+++   +  +     S GE                         K +IE L+  +  S  + E + +L+      E    +  + P     Y TS+ +Q++W+  R+  NLL NPQ S  QL V +     +G +YF LK +A+   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYFF K++ D++P++  P+++F  I YFM GL+    AFF     L++      S+A  ++   SV  +A ++  I +VFMMV 
Sbjct:  180 QFIRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLVFHGPAQKA-LEYFASAGYHCEPYNNPADFFLDVINGD--SSAVMLNREEQDNEANKTEEPSKGE-------------------------KPVIENLSEFYINSAIYGETKAELDQLPGAQEKKGTSAFKEP----VYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGAIYFDLKYDAA-GMQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKVMSDLLPMRFLPSVIFTCILYFMLGLKKTVDAFFIMMFTLIMVAYTASSMALAIATGQSVVSVATLLMTIAFVFMMVL 551          

HSP 2 Score: 190.274 bits (482), Expect = 6.623e-124
Identity = 91/148 (61.49%), Postives = 117/148 (79.05%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +T  +G ++SFH I+Y+ K K  +   K+V K IL+++NG+M PG+NAI+GPTG GKSS+LDVLA RKDPK L G VLI+G PQP +FKC SGYVVQDD+VMGTLTVRENL+FSAALRL T +  ++++ ++  IIKELGL  VADSK
Sbjct:   29 RTLAEGDVLSFHHITYRVKVKSGFLVRKTVEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPKGLSGDVLINGAPQPAHFKCCSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMKNHEKNERINTIIKELGLEKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Mouse
Match: Abcg3 (ATP binding cassette subfamily G member 3 [Source:MGI Symbol;Acc:MGI:1351624])

HSP 1 Score: 227.254 bits (578), Expect = 1.257e-96
Identity = 164/504 (32.54%), Postives = 258/504 (51.19%), Query Frame = 1
Query: 1090 RKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEV-KRMLLSVSKVGR--PKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISCY----VTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            RKR +I MEL+T+  ++FLD+PTTGLD  T   VI  L+R+S+ G+TII SI+QP+YSI+K FD  T++A GK+++HG +  A L YF + GY+ E HNNPADF++D++NG   N   ILD +               +Y E+ +R      K+     +S L S+ + I+++L    E+ L                        R  ++  T  T + +Q+KW+  ++  N    P  + IQ  + +  A ++G  +  LK +  ++ Q R GL +   +     ++ A E+F+ +R  F+HE++SGYYRVSSYFF KLL +++P ++ P+ VF  ITY +AG+++    FF     +++   +  S+   + A  +   +  ++  I +VFM+ FSG  +   S    L W QY S   +    L  NE   Q  C    T     C+     TG  FL   G   L  W  W+N L L    +  L + YVQL +V   +
Sbjct:  184 RKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVILVLRRMSKKGRTIIFSINQPQYSIFKFFDSLTLVASGKVMFHGPAQDA-LEYFRSAGYNYESHNNPADFFLDVINGGFSN---ILDTEEDG--------HEDDKYEELFERQYQVTGKLANMYAQSPLYSETRAILDQLL--GEQKLE-----------------------RSSAVETTCVTPFCHQLKWIICQSFKNFKGFPWVTVIQAIITVILATAVGTAFRVLKNDC-IEVQMRAGLLYLLTIFQCITSVSAGELFVIDRVRFLHEHTSGYYRVSSYFFGKLLAELIPRRLLPSTVFSLITYVIAGVKMSMKCFFTMICTIMVLAYSASSLPLSIGAGENAVAVPTLLVTIYFVFMLFFSGLSLYSGSFLPKLSWIQYFSIPHYGFRALLHNEFLGQNFCPEHNTEEVSRCHNYVICTGEEFLMIQGI-DLSSWGFWENHLALVCTMIILLTITYVQLLQVKNIR 648          

HSP 2 Score: 147.902 bits (372), Expect = 1.257e-96
Identity = 71/147 (48.30%), Postives = 106/147 (72.11%), Query Frame = 2
Query:  605 NVDHRKTPTKGSIISFHSISYKAKSKK-YPWSKSVTKII-LNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGL 1039
            N    KT T+ +++SFH+ISY+   +  +P  K    I  L+N++G+M PG+NAIMGP    +S +LDVLA R+DP+ L G +LI+G+P+P NFKC SGYV Q+D+V+GT+TVR+NLEFSAALRL   IT++++  ++  +++ L L
Sbjct:   24 NTSDLKTLTEEAVLSFHNISYQETVQSGFPLRKKAYVIERLSNISGIMKPGLNAIMGPQDGSRSLLLDVLAARRDPRGLSGDILINGKPRPANFKCTSGYVPQNDVVLGTVTVRDNLEFSAALRLPVTITRDEKRRRINEVLELLHL 170          
BLAST of ABC transporter domain-containing protein vs. Ensembl Mouse
Match: Abcg3 (ATP binding cassette subfamily G member 3 [Source:MGI Symbol;Acc:MGI:1351624])

HSP 1 Score: 200.29 bits (508), Expect = 1.192e-88
Identity = 137/438 (31.28%), Postives = 219/438 (50.00%), Query Frame = 1
Query: 1090 RKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEV-KRMLLSVSKVGR--PKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCY 2394
            RKR +I MEL+T+  ++FLD+PTTGLD  T   VI  L+R+S+ G+TII SI+QP+YSI+K FD  T++A GK+++HG +  A L YF + GY+ E HNNPADF++D++NG   N   ILD +               +Y E+ +R      K+     +S L S+ + I+++L    E+ L                        R  ++  T  T + +Q+KW+  ++  N    P  + IQ  + +  A ++G  +  LK +                          IE+ ++      HE++SGYYRVSSYFF KLL +++P ++ P+ VF  ITY +AG+++    FF     +++   +  S+   + A  +   +  ++  I +VFM+ FSG  +   S    L W QY S   +    L  NE   Q +
Sbjct:  184 RKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVILVLRRMSKKGRTIIFSINQPQYSIFKFFDSLTLVASGKVMFHGPAQDA-LEYFRSAGYNYESHNNPADFFLDVINGGFSN---ILDTEEDG--------HEDDKYEELFERQYQVTGKLANMYAQSPLYSETRAILDQLL--GEQKLE-----------------------RSSAVETTCVTPFCHQLKWIICQSFKNFKGFPWVTVIQAIITVILATAVGTAFRVLKND-------------------------CIEVQMR------HEHTSGYYRVSSYFFGKLLAELIPRRLLPSTVFSLITYVIAGVKMSMKCFFTMICTIMVLAYSASSLPLSIGAGENAVAVPTLLVTIYFVFMLFFSGLSLYSGSFLPKLSWIQYFSIPHYGFRALLHNEFLGQNF 553          

HSP 2 Score: 148.673 bits (374), Expect = 1.192e-88
Identity = 71/147 (48.30%), Postives = 106/147 (72.11%), Query Frame = 2
Query:  605 NVDHRKTPTKGSIISFHSISYKAKSKK-YPWSKSVTKII-LNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGL 1039
            N    KT T+ +++SFH+ISY+   +  +P  K    I  L+N++G+M PG+NAIMGP    +S +LDVLA R+DP+ L G +LI+G+P+P NFKC SGYV Q+D+V+GT+TVR+NLEFSAALRL   IT++++  ++  +++ L L
Sbjct:   24 NTSDLKTLTEEAVLSFHNISYQETVQSGFPLRKKAYVIERLSNISGIMKPGLNAIMGPQDGSRSLLLDVLAARRDPRGLSGDILINGKPRPANFKCTSGYVPQNDVVLGTVTVRDNLEFSAALRLPVTITRDEKRRRINEVLELLHL 170          
BLAST of ABC transporter domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UNQ0|ABCG2_HUMAN (Broad substrate specificity ATP-binding cassette transporter ABCG2 OS=Homo sapiens OX=9606 GN=ABCG2 PE=1 SV=3)

HSP 1 Score: 323.939 bits (829), Expect = 5.159e-138
Identity = 206/509 (40.47%), Postives = 302/509 (59.33%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISC---YVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RGVSGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A G++++HG +  A L YF + GYH E +NNPADF++DI+NG+           ++ +R      E   + +E+    +  SK  +P          +IEKL   +  S  +KE + +L+      +       +     I+Y TS+ +Q++W+  R+  NLL NPQ S  Q+ V +     +G +YFGLK + S   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYF  KLL D++P+++ P+I+F  I YFM GL+  A AFF     L++   +  S+A  ++A  SV  +A ++  I +VFMM+FSG  +N+++I SWL W QY S  R+    L  NE   Q  C  L    N  C     TG  +L + G   L PW LWKN + L  + + FL + Y++L  + KY
Sbjct:  181 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEA-LGYFESAGYHCEAYNNPADFFLDIINGD--------STAVALNR------EEDFKATEI----IEPSKQDKP----------LIEKLAEIYVNSSFYKETKAELHQLSGGEKKKKITVFK----EISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKND-STGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGI-DLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 654          

HSP 2 Score: 191.815 bits (486), Expect = 5.159e-138
Identity = 92/149 (61.74%), Postives = 118/149 (79.19%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK--YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K  T+G+++SFH+I Y+ K K    P  K V K IL+N+NG+M PG+NAI+GPTG GKSS+LDVLA RKDP  L G VLI+G P+P NFKC SGYVVQDD+VMGTLTVRENL+FSAALRL+T +T ++++ ++  +I+ELGL  VADSK
Sbjct:   29 KAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSK 177          
BLAST of ABC transporter domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5MB13|ABCG2_MACMU (Broad substrate specificity ATP-binding cassette transporter ABCG2 OS=Macaca mulatta OX=9544 GN=ABCG2 PE=2 SV=1)

HSP 1 Score: 326.25 bits (835), Expect = 7.019e-138
Identity = 206/511 (40.31%), Postives = 307/511 (60.08%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSI--SITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISC---YVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RGVSGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A G++++HG +  A L YF + GYH E +NNPADF++DI+NG+           ++ +R      E   + +E+    +  SK  +P          ++EKL   + +S  +KE + +L+         +  E +  ++   I+Y TS+ +Q++W+  R+  NLL NPQ S  Q+ V +     +G +YFGL  + S   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYFF KLL D++P+++ P+I+F  I YFM GL+  A AFF     L++   +  S+A  ++A  SV  +A ++  I +VFMM+FSG  +N+++I SWL W QY S  R+    L  NE   Q  C  L    N +C     TG  +L + G   L PW LWKN + L  + + FL + Y++L  + KY
Sbjct:  181 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEA-LGYFESAGYHCEAYNNPADFFLDIINGD--------STAVALNR------EEDFKATEI----IEPSKRDKP----------LVEKLAEIYVDSSFYKETKAELHQL-------SGGEKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVILGLVIGAIYFGLNND-STGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPTADAFFIMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATVNNTCNYATCTGEEYLAKQGI-DLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 653          

HSP 2 Score: 189.119 bits (479), Expect = 7.019e-138
Identity = 93/150 (62.00%), Postives = 117/150 (78.00%), Query Frame = 2
Query:  617 RKTPTKGSIISFHSISY--KAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            RK  T+G+++SFH+I Y  K KS   P  K V K IL+N+NG+M PG+NAI+GPTG GKSS+LDVLA RKDP  L G VLI+G  +P NFKC SGYVVQDD+VMGTLTVRENL+FSAALRL T +T ++++ ++  +I+ELGL  VADSK
Sbjct:   28 RKAFTEGAVLSFHNICYRVKVKSGFLPGRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGALRPTNFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMTNHEKNERINRVIQELGLDKVADSK 177          
BLAST of ABC transporter domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4GZT4|ABCG2_BOVIN (Broad substrate specificity ATP-binding cassette transporter ABCG2 OS=Bos taurus OX=9913 GN=ABCG2 PE=3 SV=2)

HSP 1 Score: 326.25 bits (835), Expect = 2.863e-137
Identity = 206/509 (40.47%), Postives = 301/509 (59.14%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISC---YVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RGVSGGERKR +I MELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A G++++HG +  A L YF  +G+  EP+NNPADF++DI+NG+           +  +R  I   + + E  E        SK   P          +IEKL   +  S  FKE + +L+ +      D   +  P    +TYATS+ +Q+KW+  R+  NLL NPQ S  QL V +F    +G +++ LK + +   QNR G+ FF      F ++ A+E+ + E+ +FIHE  SGYYRVSSYFF KLL D++P+++ P+I+F  ITYF+ GL+    AFF   L L++   +  S+A  ++A  SV  +A ++  I +VFMM+FSG  +N+ ++  WL W QYLS  R+    L  NE   Q  C  L    N +C     TG  FL   G   + PW LWKN + L  + + FL + Y++L  + K+
Sbjct:  180 QFIRGVSGGERKRTSIAMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEA-LGYFGAIGFRCEPYNNPADFFLDIINGD--------SSAVVLNREDIG--DEANETEE-------PSKKDTP----------LIEKLAEFYVNSSFFKETKVELDKFS----GDQRRKKLPSYKEVTYATSFCHQLKWISRRSFKNLLGNPQASIAQLIVTVFLGLVIGAIFYDLKNDPA-GIQNRAGVLFFLTTNQCFSSVSAVELLVVEKKLFIHEYISGYYRVSSYFFGKLLSDLLPMRMLPSIIFTCITYFLLGLKPKVEAFFIMMLTLMMVAYSASSMALAIAAGQSVVSIATLLMTISFVFMMIFSGLLVNLKTVVPWLSWLQYLSIPRYGYAALQHNEFLGQNFCPGLNVTTNNTCSYAICTGEEFLTNQGI-DISPWGLWKNHVALACMIVIFLTIAYLKLLFLKKF 654          

HSP 2 Score: 187.193 bits (474), Expect = 2.863e-137
Identity = 90/149 (60.40%), Postives = 116/149 (77.85%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK--YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +T T+G+++SFH+I Y+ K K       K++ K IL N+NGVM PG+NAI+GPTG GKSS+LD+LA RKDP  L G VLI+G P+P NFKC SGYVVQDD+VMGTLTVRENL+FSAALRL T +T  +++ ++  +I+ELGL  VADSK
Sbjct:   28 QTLTEGAVLSFHNICYRVKVKTGFLLCRKTIEKEILANINGVMKPGLNAILGPTGGGKSSLLDILAARKDPHGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMTSYEKNERINKVIQELGLDKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7TMS5|ABCG2_MOUSE (Broad substrate specificity ATP-binding cassette transporter ABCG2 OS=Mus musculus OX=10090 GN=Abcg2 PE=1 SV=1)

HSP 1 Score: 322.783 bits (826), Expect = 6.858e-137
Identity = 198/511 (38.75%), Postives = 295/511 (57.73%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISCY-----VTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            + +RG+SGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A GK+++HG +  A L YF + GYH EP+NNPADF++D++NG+  +   +L+++   +  +     S GE                         K +IE L+  +  S  + E + +L+      E    +  + P     Y TS+ +Q++W+  R+  NLL NPQ S  QL V +     +G +YF LK +A+   QNR G+ FF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYFF K++ D++P++  P+++F  + YFM GL+    AFF     L++      S+A  ++   SV  +A ++  I +VFMM+FSG  +N+ +I  WL W QY S  R+    L  NE   Q  C       N +C       TGN +L   G   L PW LWKN + L  + + FL + Y++L  + KY
Sbjct:  180 QFIRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLVFHGPAQKA-LEYFASAGYHCEPYNNPADFFLDVINGD--SSAVMLNREEQDNEANKTEEPSKGE-------------------------KPVIENLSEFYINSAIYGETKAELDQLPGAQEKKGTSAFKEP----VYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGAIYFDLKYDAA-GMQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKVMSDLLPMRFLPSVIFTCVLYFMLGLKKTVDAFFIMMFTLIMVAYTASSMALAIATGQSVVSVATLLMTIAFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQYNEFLGQEFCPGFNVTDNSTCVNSYAICTGNEYLINQGI-ELSPWGLWKNHVALACMIIIFLTIAYLKLLFLKKY 656          

HSP 2 Score: 189.119 bits (479), Expect = 6.858e-137
Identity = 91/148 (61.49%), Postives = 117/148 (79.05%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +T  +G ++SFH I+Y+ K K  +   K+V K IL+++NG+M PG+NAI+GPTG GKSS+LDVLA RKDPK L G VLI+G PQP +FKC SGYVVQDD+VMGTLTVRENL+FSAALRL T +  ++++ ++  IIKELGL  VADSK
Sbjct:   29 RTLAEGDVLSFHHITYRVKVKSGFLVRKTVEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPKGLSGDVLINGAPQPAHFKCCSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMKNHEKNERINTIIKELGLEKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80W57|ABCG2_RAT (Broad substrate specificity ATP-binding cassette transporter ABCG2 OS=Rattus norvegicus OX=10116 GN=Abcg2 PE=1 SV=1)

HSP 1 Score: 325.479 bits (833), Expect = 2.198e-136
Identity = 205/511 (40.12%), Postives = 295/511 (57.73%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISCY-----VTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            +  RG+SGGERKR +IGMELITDPS++FLDEPTTGLD+ TA +V+  L+R+S+ G+TII SIHQP+YSI+KLFD  T++A GK+++HG +  A L YF + GYH EP+NNPADF++D++NG+                   AV+ + GE           SK  +P          IIE L   +  S  + E + +L+   V  +    +  R P     Y TS+ +Q++W+  R+  NLL NPQ S  QL V +     +G +YFGLK + +   QNR G+FFF      F ++ A+E+F+ E+ +FIHE  SGYYRVSSYFF KL+ D++P++  P++++  I YFM GL+    AFF     L++      S+A  ++A  SV  +A ++  I +VFMM+FSG  +N+ +I  WL W QY S  R+    L  NE   Q  C  L    N +C       TGN +L   G   L PW LW+N + L  + + FL + Y++L  + KY
Sbjct:  180 QFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKA-LEYFASAGYHCEPYNNPADFFLDVINGDSS-----------------AVMLNRGEQDHEANKTEEPSKREKP----------IIENLAEFYINSTIYGETKAELDQLPVAQKKKGSSAFREP----VYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGALYFGLKNDPT-GMQNRAGVFFFLTTNQCFTSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKLVSDLLPMRFLPSVIYTCILYFMLGLKRTVEAFFIMMFTLIMVAYTASSMALAIAAGQSVVSVATLLMTISFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQHNEFLGQEFCPGLNVTMNSTCVNSYTICTGNDYLINQGI-DLSPWGLWRNHVALACMIIIFLTIAYLKLLFLKKY 656          

HSP 2 Score: 184.882 bits (468), Expect = 2.198e-136
Identity = 89/148 (60.14%), Postives = 115/148 (77.70%), Query Frame = 2
Query:  620 KTPTKGSIISFHSISYKAKSKK-YPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +T  +G ++SFH I+Y+ K K  +   K+  K IL+++NG+M PG+NAI+GPTG GKSS+LDVLA RKDP+ L G VLI+G PQP NFKC SGYVVQDD+VMGTLTVRENL+FSAALRL   +  ++++ ++  IIKELGL  VADSK
Sbjct:   29 RTLAEGDVLSFHHITYRVKVKSGFLVRKTAEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPRGLSGDVLINGAPQPANFKCSSGYVVQDDVVMGTLTVRENLQFSAALRLPKAMKTHEKNERINTIIKELGLDKVADSK 176          
BLAST of ABC transporter domain-containing protein vs. TrEMBL
Match: A0A4E0R840 (Placenta-specific ATP-binding cassette transporter OS=Fasciola hepatica OX=6192 GN=D915_006162 PE=4 SV=1)

HSP 1 Score: 409.838 bits (1052), Expect = 1.550e-170
Identity = 259/515 (50.29%), Postives = 340/515 (66.02%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPP----SISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKT------FPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            +L+RGVSGGERKR NIGMELITDPSV+FLDEPTTGLDAF A  V+KTL+ LSR G+TII SIHQPKYSIYKLFD  T++ +G+++YHG +   P+ YF NLGY  E HNNP DF++DIL+GE               +R +  ++ +    E ++M L                  + E+L  +W++S   + + ++ NA      + ++   +P     +  I+YA  +  Q+  +CWRT++NLLR+P  S +Q  VYLFFA SMG VYF +        QNR GLFFF+ LQVVFVNLG+IE+FIKER +FIHENSSGYYRVS YFFSK++CD++P KV P +VF+PI Y+MAGLR DA AFFFFELIL LTT A  ++A F+SA+F++FG+ANVV  I+YVFMMVF GY +N+ S+ +WL W +YLS FR++LGGL V EM    +   T       P+      G  +L      Y  PWDLW N  G  +I+L F +LCY+QLRR+ KYK
Sbjct:  404 DLIRGVSGGERKRTNIGMELITDPSVLFLDEPTTGLDAFMAGQVVKTLKTLSRRGRTIIFSIHQPKYSIYKLFDSLTLVYRGRLVYHGPARHHPIRYFINLGYECENHNNPPDFFMDILHGEAP-------------QRAMDGVDLNHIIEEPEQMHL------------------VGERLVREWDQSAECQSVLKEANAIASGLSESSNNLHKPKRRKNASEISYAVPFCRQLNQVCWRTSVNLLRDPLASIVQTVVYLFFAISMGTVYFKMNKSLESGIQNRAGLFFFSTLQVVFVNLGSIELFIKERVLFIHENSSGYYRVSVYFFSKIMCDILPTKVLPVLVFMPICYWMAGLRTDAAAFFFFELILSLTTLAAAAIALFISATFTLFGIANVVVSIVYVFMMVFGGYLINLKSMGAWLSWLRYLSIFRYSLGGLMVMEMNPLQFCPATNTSTPQLPDTRQCQPGTQYLYDQDIGYETPWDLWMNVFGQIMITLGFYVLCYIQLRRIKKYK 887          

HSP 2 Score: 222.246 bits (565), Expect = 1.550e-170
Identity = 102/151 (67.55%), Postives = 128/151 (84.77%), Query Frame = 2
Query:  608 VDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            + HR T   G+ +SFH I Y+ K KK PWS++VT+ +L++V+G++ PGVNAIMGPTGSGKSS+LDVLAGRKDP++L G+VL+DG PQPKNFKC+SGYVVQDDIVMGTLTVRENL FSAALR++ + +K +R  KV  II+ELGL+AVADSK
Sbjct:  251 ISHRTT-INGATLSFHHIRYEVKMKKMPWSRAVTRTVLDDVSGILRPGVNAIMGPTGSGKSSLLDVLAGRKDPRFLSGQVLVDGAPQPKNFKCVSGYVVQDDIVMGTLTVRENLYFSAALRMTLKCSKAERKQKVNEIIEELGLAAVADSK 400          
BLAST of ABC transporter domain-containing protein vs. TrEMBL
Match: A0A504YX08 (Placenta-specific ATP-binding cassette transporter OS=Fasciola gigantica OX=46835 GN=FGIG_08034 PE=4 SV=1)

HSP 1 Score: 407.912 bits (1047), Expect = 5.870e-170
Identity = 259/515 (50.29%), Postives = 340/515 (66.02%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTD----AEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKT------FPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            +L+RGVSGGERKR NIGMELITDPSV+FLDEPTTGLDAF A  V+KTL+ LSR G+TII SIHQPKYSIYKLFD  T++ +G+++YHG +   P+ YF NLGY  E HNNP DF++DIL+GE               +R +  ++ +    E ++M L                  + E+L  +W++S   + + ++ NA      + ++     + R  +  I+YA  +  Q+  +CWRT++NLLR+P  S +Q  VYLFFA SMG VYF +        QNR GLFFF+ LQVVFVNLG+IE+FIKER +FIHENSSGYYRVS YFFSK++CD++P KV P +VF+PI Y+MAGLR DA AFFFFELIL LTT A  ++A F+SA+F++FG+ANVV  I+YVFMMVF GY +N+ S+ +WL W +YLS FR++LGGL V EM    +   T       P+      G  +L      Y  PWDLW N  G  +I+L F +LCY+QLRR+ KYK
Sbjct:  404 DLIRGVSGGERKRTNIGMELITDPSVLFLDEPTTGLDAFMAGQVVKTLKTLSRRGRTIIFSIHQPKYSIYKLFDSLTLVYRGRLVYHGPARHHPIRYFINLGYECENHNNPPDFFMDILHGEAP-------------QRAMDGVDLNHTIEEPEQMHL------------------VGERLVREWDQSAECQSVLKEANAIASGLSESSNNLHKTKRRKNASEISYAVPFCRQLNQVCWRTSVNLLRDPLASIVQTVVYLFFAVSMGTVYFKMNKSLESGIQNRAGLFFFSTLQVVFVNLGSIELFIKERVLFIHENSSGYYRVSVYFFSKIMCDILPTKVLPVLVFMPICYWMAGLRADAAAFFFFELILSLTTLAAAAIALFISATFTLFGIANVVVSIVYVFMMVFGGYLINLKSMGAWLSWLRYLSIFRYSLGGLMVMEMNPLQFCPATNTSTPQLPDTRQCQPGTQYLYDQDIGYETPWDLWMNVFGQIMITLGFYVLCYIQLRRIKKYK 887          

HSP 2 Score: 222.246 bits (565), Expect = 5.870e-170
Identity = 102/151 (67.55%), Postives = 128/151 (84.77%), Query Frame = 2
Query:  608 VDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            + HR T   G+ +SFH I Y+ K KK PWS++VT+ +L++V+G++ PGVNAIMGPTGSGKSS+LDVLAGRKDP++L G+VL+DG PQPKNFKC+SGYVVQDDIVMGTLTVRENL FSAALR++ + +K +R  KV  II+ELGL+AVADSK
Sbjct:  251 ISHRTT-INGATLSFHHIRYEVKMKKMPWSRAVTRTVLDDVSGILRPGVNAIMGPTGSGKSSLLDVLAGRKDPRFLSGQVLVDGAPQPKNFKCVSGYVVQDDIVMGTLTVRENLYFSAALRMTLKCSKAERKQKVNEIIEELGLAAVADSK 400          
BLAST of ABC transporter domain-containing protein vs. TrEMBL
Match: A0A4V3SGC8 (ABC transporter domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002408 PE=4 SV=1)

HSP 1 Score: 404.831 bits (1039), Expect = 3.728e-169
Identity = 252/522 (48.28%), Postives = 338/522 (64.75%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDK----KVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPP-------SISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCY------TLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            +L+RGVSGGERKR NIGMELITDP V+FLDEPTTGLDAF A  VIKTL+ LSR G+TII SIHQPKYSIYKLFD  T++ +G+++YHG++  AP+ YF  LGY  E HNNP+DF++DIL+GE  +                                      G P SD   D+     ++ E+L  +W+ES  ++ + +++ A       D      PP       +  ++YA  +  Q+  +CWRT++NLLR+P  S +Q  VYLFFA SMG VYF +        QNR GLFFF+ LQVVFVNLG+IE+FIKER +FIHENSSGYYR+S+YF SK+LCD++P KV P ++F+PI Y+M GL  + GAFF+FEL+L +TT A  ++A F+SA+F++FG+ANVV  I++VFMMVF GY +N+ S+ +WL W +YLS FR+++GGL   EM+   +      ++   P+     +G ++L      Y   WDLW N  G  LI +FF ILCYVQLRR+NKYK
Sbjct:  178 DLIRGVSGGERKRTNIGMELITDPPVLFLDEPTTGLDAFMAGQVIKTLKNLSRRGRTIIFSIHQPKYSIYKLFDSLTMVFRGRLVYHGRAKYAPIEYFLKLGYVCENHNNPSDFFMDILHGEAPHRP-----------------------------------TGGPDSDTPLDEPEHIHLVGERLVKEWDESAEYELILKEVAAIAKRLHPDGAG---PPGNGKSAITTDVSYAVPFCRQLNQVCWRTSLNLLRDPLASVVQTLVYLFFALSMGTVYFQMDTSLESGIQNRAGLFFFSTLQVVFVNLGSIELFIKERVLFIHENSSGYYRISAYFLSKILCDILPTKVLPVLLFMPICYWMVGLLPEVGAFFYFELLLSITTLAAAAIALFMSATFTLFGIANVVVSILFVFMMVFGGYLINLKSMAAWLSWLRYLSIFRYSMGGLLTAEMRSLTFCPVTNTSVPGAPDNRQCQSGTLYLRDQDLPYATAWDLWSNVFGQVLIMIFFYILCYVQLRRINKYK 661          

HSP 2 Score: 222.631 bits (566), Expect = 3.728e-169
Identity = 104/152 (68.42%), Postives = 128/152 (84.21%), Query Frame = 2
Query:  605 NVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +V  + T   GS +SFH ISY+ K KK PWS+ VTK +LN+V+G++ PG+NAIMGPTGSGKSS+LDVLAGRKDP++L G+VL+DG PQPKNFKC+SGYVVQDDIVMGTLTVRENL FSAALR++ R +K +R  KV  II+ELGL++VADSK
Sbjct:   23 SVTSQTTYLSGSTLSFHHISYEVKLKKMPWSRPVTKTVLNDVSGLLRPGLNAIMGPTGSGKSSLLDVLAGRKDPRFLSGQVLVDGVPQPKNFKCISGYVVQDDIVMGTLTVRENLHFSAALRMTVRCSKAERRRKVDEIIEELGLTSVADSK 174          
BLAST of ABC transporter domain-containing protein vs. TrEMBL
Match: A0A4S2M6N0 (ABC transporter domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002408 PE=4 SV=1)

HSP 1 Score: 404.06 bits (1037), Expect = 4.290e-169
Identity = 252/522 (48.28%), Postives = 338/522 (64.75%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDK----KVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPP-------SISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCY------TLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            +L+RGVSGGERKR NIGMELITDP V+FLDEPTTGLDAF A  VIKTL+ LSR G+TII SIHQPKYSIYKLFD  T++ +G+++YHG++  AP+ YF  LGY  E HNNP+DF++DIL+GE  +                                      G P SD   D+     ++ E+L  +W+ES  ++ + +++ A       D      PP       +  ++YA  +  Q+  +CWRT++NLLR+P  S +Q  VYLFFA SMG VYF +        QNR GLFFF+ LQVVFVNLG+IE+FIKER +FIHENSSGYYR+S+YF SK+LCD++P KV P ++F+PI Y+M GL  + GAFF+FEL+L +TT A  ++A F+SA+F++FG+ANVV  I++VFMMVF GY +N+ S+ +WL W +YLS FR+++GGL   EM+   +      ++   P+     +G ++L      Y   WDLW N  G  LI +FF ILCYVQLRR+NKYK
Sbjct:  481 DLIRGVSGGERKRTNIGMELITDPPVLFLDEPTTGLDAFMAGQVIKTLKNLSRRGRTIIFSIHQPKYSIYKLFDSLTMVFRGRLVYHGRAKYAPIEYFLKLGYVCENHNNPSDFFMDILHGEAPHRP-----------------------------------TGGPDSDTPLDEPEHIHLVGERLVKEWDESAEYELILKEVAAIAKRLHPDGAG---PPGNGKSAITTDVSYAVPFCRQLNQVCWRTSLNLLRDPLASVVQTLVYLFFALSMGTVYFQMDTSLESGIQNRAGLFFFSTLQVVFVNLGSIELFIKERVLFIHENSSGYYRISAYFLSKILCDILPTKVLPVLLFMPICYWMVGLLPEVGAFFYFELLLSITTLAAAAIALFMSATFTLFGIANVVVSILFVFMMVFGGYLINLKSMAAWLSWLRYLSIFRYSMGGLLTAEMRSLTFCPVTNTSVPGAPDNRQCQSGTLYLRDQDLPYATAWDLWSNVFGQVLIMIFFYILCYVQLRRINKYK 964          

HSP 2 Score: 223.402 bits (568), Expect = 4.290e-169
Identity = 104/152 (68.42%), Postives = 128/152 (84.21%), Query Frame = 2
Query:  605 NVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +V  + T   GS +SFH ISY+ K KK PWS+ VTK +LN+V+G++ PG+NAIMGPTGSGKSS+LDVLAGRKDP++L G+VL+DG PQPKNFKC+SGYVVQDDIVMGTLTVRENL FSAALR++ R +K +R  KV  II+ELGL++VADSK
Sbjct:  326 SVTSQTTYLSGSTLSFHHISYEVKLKKMPWSRPVTKTVLNDVSGLLRPGLNAIMGPTGSGKSSLLDVLAGRKDPRFLSGQVLVDGVPQPKNFKCISGYVVQDDIVMGTLTVRENLHFSAALRMTVRCSKAERRRKVDEIIEELGLTSVADSK 477          
BLAST of ABC transporter domain-containing protein vs. TrEMBL
Match: A0A267EIC8 (ABC transporter domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010405g1 PE=4 SV=1)

HSP 1 Score: 419.853 bits (1078), Expect = 4.472e-169
Identity = 267/520 (51.35%), Postives = 337/520 (64.81%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEV---KNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDL-----KSDKKVIIEKLTYDWEESLNFKELRRQLNA-YDVITEDDTDAEIRPPSIS----ITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK--DQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            EL+RGVSGGERKR NIGMELITDPSV+FLDEPTTGLDAFTA SV++TL+ L+ +G+TI+ SIHQPKYSIY+LFD  T++  G+IIYHG +G  PL YF N+GYH E HN+P DF++DI++GEV       E     +          +   E   +++  +  ++V +  S +     KS    I ++L   W++      + +Q+   Y          E     +     + Y T   NQ+ W+ WRTA+NL RNPQ+S IQL VYLFF  S+G V+FGL        QNR GLFFF  LQ+VFVNLGAIE+FIKER IFIHENSSG+YRVS YF +K+ CDM+PIK  P ++F+PI YFM+ L+LDAGAFFF+EL L+L T A C VAFFVSAS SVFG+AN+   IIYVFMMVF G+ MNISS+  WL WC+Y S F +A  GL VNE    D C    T        +G V L      Y   WDLW N  G+ LI++FFL LCY+QLRR+ KYK
Sbjct:  491 ELIRGVSGGERKRTNIGMELITDPSVLFLDEPTTGLDAFTAGSVLRTLRNLANAGRTIVFSIHQPKYSIYRLFDNLTLVVAGRIIYHGPAGDMPLRYFANIGYHCEAHNSPPDFFMDIVHGEVPVTNAGGEGGRAALISGGGSGGDFDDCNELPMIRQNFVPTAQVTKRDSVIDTDIQKSHSAAIGQQLIERWQQCPMAHRVEQQVEEIYQQSLRMGNGGEGSHVKVKKGAWVGYPTGLWNQVVWVSWRTALNLFRNPQSSIIQLVVYLFFGISIGTVFFGLDTSLESGIQNRQGLFFFLILQMVFVNLGAIEVFIKERVIFIHENSSGFYRVSVYFLAKIFCDMLPIKTLPVVLFMPIVYFMSRLKLDAGAFFFYELNLVLATCAACGVAFFVSASVSVFGIANIFISIIYVFMMVFGGFLMNISSMGDWLAWCKYFSVFNYAYAGLSVNEFVGLDFCPMRNTTNVTRTCKSGYVVLSDQQIAYKTGWDLWSNEFGMLLITMFFLALCYIQLRRIKKYK 1010          

HSP 2 Score: 207.223 bits (526), Expect = 4.472e-169
Identity = 95/142 (66.90%), Postives = 120/142 (84.51%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            GS+I+F +I+Y    K+YPWSK+  +++L +V+G+M PG+NAIMGPTGSGKSS+LDVLAGRKDP++L G+VL+DG  QP+NFKC+SGYVVQDDIVMGTLTVRENL FSAALRL   +T  +R  KV ++I+ELGLS VADSK
Sbjct:  346 GSVITFRNINYTVLVKRYPWSKAEKRVVLQSVSGIMRPGLNAIMGPTGSGKSSLLDVLAGRKDPQFLRGEVLVDGAEQPENFKCVSGYVVQDDIVMGTLTVRENLRFSAALRLPGSVTDLERRRKVESVIEELGLSKVADSK 487          
BLAST of ABC transporter domain-containing protein vs. Ensembl Cavefish
Match: abcg2d (ATP-binding cassette sub-family G member 2 [Source:NCBI gene;Acc:103045074])

HSP 1 Score: 325.865 bits (834), Expect = 4.867e-140
Identity = 209/512 (40.82%), Postives = 295/512 (57.62%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSE-VKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK--DQCYTLKT-----FPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            EL+RG+SGGERKR NIGMELI DPSV+FLDEPTTGLDA TA SV+  L+R++ +G+TII+SIHQP+YSIY+LFD  T++  G+++YHG + +A L+YF N+GY  E HNNPADF++D++NG+      I               E SG+  + ++  L+   K      D  ++   II+   Y                             IRP S  ITY + + +Q  W+  RT  NL+ NPQTS  QLGV +F A  +G +++ +K   S   QNRFG  FF      F  L A E+FI ER +FIHE +SGYYRVS YF +K+L D++ ++  PAI+F  ++YFM G +  A AFF F   + L +    ++   +SA  SV  +AN+   I +VFMM+FSG  +N+ S+ +WL W +Y S  R+AL  L +NE    + C    T        I+C  TG   L   G  Y   W LW+N L L ++++ FLI+ Y++LR + K+
Sbjct:  184 ELIRGISGGERKRTNIGMELIIDPSVLFLDEPTTGLDASTANSVLHLLKRMANNGRTIIMSIHQPRYSIYRLFDSLTLLVSGRLVYHGPAQNA-LDYFSNIGYACEAHNNPADFFLDVINGD-----SIAATMAKLQNAEAIEFEESGDRRQSIEARLVEEYKNSSYAQDTNTELARIIQGKEYS----------------------------IRPKSRVITYNSGFCHQFNWVLKRTFRNLMLNPQTSVAQLGVTVFLALIVGAIFYKVKDNQS-GIQNRFGALFFITTNQCFSTLSAAELFITERKLFIHEYTSGYYRVSVYFLTKILSDIITLRTIPAILFTCVSYFMIGFKPTAAAFFIFMFTVTLVSYTATAMTMAISADQSVVAVANIFMTISFVFMMIFSGLLVNLESVMAWLNWLKYFSIPRYALTALEINEFVGLNFCGNFTTRLANDTQGITC--TGEQHLKSQGIDY-STWGLWQNHLALIIMTIIFLIIAYIKLRFIRKF 657          

HSP 2 Score: 193.741 bits (491), Expect = 4.867e-140
Identity = 92/145 (63.45%), Postives = 114/145 (78.62%), Query Frame = 2
Query:  632 KGSIISFHSISYKAKSKKYPWSKS--VTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            +GS +SFH+I Y  K K  P  K   +TK IL ++NG+M PG+NAI+GPTG GKSS LDVLA RKDP  L G+VLIDG PQP NFKC+SGYVVQDD+VMGTLTVRENL FSAALRLS+ + + ++ A+V ++I ELGLS VAD++
Sbjct:   36 RGSTVSFHNIQYSVKMKSGPLCKKKVITKDILQDLNGIMKPGLNAILGPTGGGKSSFLDVLAARKDPSGLSGEVLIDGAPQPPNFKCLSGYVVQDDVVMGTLTVRENLRFSAALRLSSSVRQKEKEARVNDLITELGLSKVADAR 180          
BLAST of ABC transporter domain-containing protein vs. Ensembl Cavefish
Match: abcg2a (ATP-binding cassette sub-family G member 2-like [Source:NCBI gene;Acc:103035202])

HSP 1 Score: 334.339 bits (856), Expect = 1.382e-137
Identity = 215/509 (42.24%), Postives = 298/509 (58.55%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK-----DQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            +L+RG+SGGERKR NIGMELI DP V+FLDEPTTGLDA TA SV+  L+R+S  G+TIILSIHQP+YSIY+LFD  T++A G+ +YHG + SA L YF  +G+  EPHNNPADF++D++NG+                   AV+ +S +  E                   S ++ I ++L  +++    +KE + +L           +   +P S +ITY TS+  Q KW+  RT  NL+ NPQTS  Q+GV LF A  +G ++FG+    S   QNR G  FF      F  L + E+FI ER +F+HE  SGYYRVS YF SK+L D++ ++ FPAI+F  + Y+M G R DAGAFFFF   + +T     ++   +SA  SV  +AN+   I +VFMM+FSG  +N+ SI  WLQW +YLS  R+ L  L VNE       D         NI+C  TG  FL   G  Y   W +W+N + L  +++ FL + Y++LR + K+
Sbjct:  182 QLIRGISGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLSLLKRMSNHGRTIILSIHQPRYSIYRLFDSLTLLAGGRQVYHGPAQSA-LEYFSEIGFACEPHNNPADFFLDVINGD-----------------STAVIRNSHQDDE-----------ELDTQQCNSSRQSIEQRLVEEYKSWSYYKETKEELEK----IMQGQNYSGKPKSRTITYNTSFCYQFKWVLKRTFRNLMLNPQTSFAQIGVTLFLALIVGAIFFGVS-NGSSGIQNRMGSLFFITTNQCFSALSSAELFITERKLFLHEYVSGYYRVSVYFLSKILSDILTLRTFPAIIFSCVAYWMIGYRADAGAFFFFMFSVAMTAYTATAMTMAISADQSVVAIANIFMTISFVFMMIFSGLLVNLPSIVDWLQWFKYLSIPRYGLTALEVNEFVGLQFCDSRPDASGALNITCS-TGEEFLTEQGIDY-STWGMWQNIVALGCMTIIFLSIAYLKLRFIKKF 654          

HSP 2 Score: 177.178 bits (448), Expect = 1.382e-137
Identity = 87/144 (60.42%), Postives = 110/144 (76.39%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            G+ +SFH I Y  + +  +   + VT K IL ++NG+M PG+NAI+G TGSGKSS LDVLA RKDPK L G+VLIDG PQP NFKC+SGYVVQDD+VMGTLTVREN  FSAALRL   +++ ++  KV  +I+ELGL+ VADS+
Sbjct:   35 GATVSFHKIHYAVEMRSGFLCKRKVTHKDILIDLNGIMKPGMNAILGATGSGKSSFLDVLAARKDPKGLTGEVLIDGAPQPPNFKCLSGYVVQDDVVMGTLTVRENFRFSAALRLPMSVSQKEKEEKVQRLIEELGLTKVADSR 178          
BLAST of ABC transporter domain-containing protein vs. Ensembl Cavefish
Match: abcg2a (ATP-binding cassette sub-family G member 2-like [Source:NCBI gene;Acc:103035202])

HSP 1 Score: 325.479 bits (833), Expect = 6.566e-135
Identity = 209/516 (40.50%), Postives = 297/516 (57.56%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK--DQCYTLK----------TFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            +L+RG+SGGERKR NIGMELI DP V+FLDEPTTGLDA TA SV+  L+R+S  G+TIILSIHQP+YSIY+LFD  T++A G+ +YHG + SA L YF  +G+  EPHNNPADF++D++NG+                   AV+ +S +  E                   S ++ I ++L  +++    +KE + +L           +   +P S +ITY TS+  Q KW+  RT  NL+ NPQTS  Q+GV LF A  +G ++FG+    S   QNR G  FF      F  L + E+FI ER +F+HE  SGYYRVS YF SK+L D++ ++ FPAI+F  + Y+M G R DAGAFFFF   + +T     ++   +SA  SV  +AN+   I +VFMM+FSG  +N+ SI  WLQW +YLS   + L  L  +E    + C T            +  +++   +G  FL   G  Y   W +WKN + L  +++  L + Y++LR + K+
Sbjct:  182 QLIRGISGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLSLLKRMSNHGRTIILSIHQPRYSIYRLFDSLTLLAGGRQVYHGPAQSA-LEYFSEIGFACEPHNNPADFFLDVINGD-----------------STAVIRNSHQDDE-----------ELDTQQCNSSRQSIEQRLVEEYKSWSYYKETKEELEK----IMQGQNYSGKPKSRTITYNTSFCYQFKWVLKRTFRNLMLNPQTSFAQIGVTLFLALIVGAIFFGVS-NGSSGIQNRMGSLFFITTNQCFSALSSAELFITERKLFLHEYVSGYYRVSVYFLSKILSDILTLRTFPAIIFSCVAYWMIGYRADAGAFFFFMFSVAMTAYTATAMTMAISADQSVVAIANIFMTISFVFMMIFSGLLVNLPSIVDWLQWIKYLSIPHYGLTALEASEFVGLEFCDTRSVSSGRPGFNASRESVTICTSGEEFLTEQGIDY-STWGMWKNIVALGCMTIILLSITYLKLRFIKKF 662          

HSP 2 Score: 177.178 bits (448), Expect = 6.566e-135
Identity = 87/144 (60.42%), Postives = 110/144 (76.39%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            G+ +SFH I Y  + +  +   + VT K IL ++NG+M PG+NAI+G TGSGKSS LDVLA RKDPK L G+VLIDG PQP NFKC+SGYVVQDD+VMGTLTVREN  FSAALRL   +++ ++  KV  +I+ELGL+ VADS+
Sbjct:   35 GATVSFHKIHYAVEMRSGFLCKRKVTHKDILIDLNGIMKPGMNAILGATGSGKSSFLDVLAARKDPKGLTGEVLIDGAPQPPNFKCLSGYVVQDDVVMGTLTVRENFRFSAALRLPMSVSQKEKEEKVQRLIEELGLTKVADSR 178          
BLAST of ABC transporter domain-containing protein vs. Ensembl Cavefish
Match: abcg2a (ATP-binding cassette sub-family G member 2-like [Source:NCBI gene;Acc:103035202])

HSP 1 Score: 304.679 bits (779), Expect = 1.225e-128
Identity = 208/516 (40.31%), Postives = 299/516 (57.95%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK--DQCYTLK----------TFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            +L+RG+SGGERKR NIGMELI DP V+FLDEPTTGLDA TA SV+  L+R+S  G+TIILSIHQP+YSIY+LFD  T++A G+ +YHG + SA L YF  +G+  EPHNNPADF++D++NG+                   AV+ +S +  E                   S ++ I ++L  +++    +KE + +L           +   +P S +ITY TS+  Q KW+  RT  NL+ NPQTS  Q+GV LF A  +G ++FG+    S   QNR G  FF      F  L + E+FI ER +F+HE  SGYYRVS Y  SK+LCD++ ++ FPAI+F  ITY+M G + +AGAFFFF L + +T     ++   +SA  SV  +AN+   I ++FM++FSG  +N+ SI  WLQW +YLS   + L  L  +E    + C T            +  +++   +G  FL   G  Y   W +WKN + L  +++  L + Y++LR + K+
Sbjct:  182 QLIRGISGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLSLLKRMSNHGRTIILSIHQPRYSIYRLFDSLTLLAGGRQVYHGPAQSA-LEYFSEIGFACEPHNNPADFFLDVINGD-----------------STAVIRNSHQDDE-----------ELDTQQCNSSRQSIEQRLVEEYKSWSYYKETKEELEK----IMQGQNYSGKPKSRTITYNTSFCYQFKWVLKRTFRNLMLNPQTSFAQIGVTLFLALIVGAIFFGVS-NGSSGIQNRMGSLFFITTNQCFSALSSAELFITERKLFLHEYVSGYYRVSVYLLSKILCDVLTLRTFPAIIFGCITYWMIGYKAEAGAFFFFMLSIAMTAYTATAMTMAISADQSVMDIANIFISISFIFMIIFSGLLVNLPSIVDWLQWIKYLSIPHYGLTALEASEFVGLEFCDTRSVSSGRPGFNASRESVTICTSGEEFLTEQGIDY-STWGMWKNIVALGCMTIILLSITYLKLRFIKKF 662          

HSP 2 Score: 177.178 bits (448), Expect = 1.225e-128
Identity = 87/144 (60.42%), Postives = 110/144 (76.39%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            G+ +SFH I Y  + +  +   + VT K IL ++NG+M PG+NAI+G TGSGKSS LDVLA RKDPK L G+VLIDG PQP NFKC+SGYVVQDD+VMGTLTVREN  FSAALRL   +++ ++  KV  +I+ELGL+ VADS+
Sbjct:   35 GATVSFHKIHYAVEMRSGFLCKRKVTHKDILIDLNGIMKPGMNAILGATGSGKSSFLDVLAARKDPKGLTGEVLIDGAPQPPNFKCLSGYVVQDDVVMGTLTVRENFRFSAALRLPMSVSQKEKEEKVQRLIEELGLTKVADSR 178          
BLAST of ABC transporter domain-containing protein vs. Ensembl Cavefish
Match: abcg2a (ATP-binding cassette sub-family G member 2-like [Source:NCBI gene;Acc:103035202])

HSP 1 Score: 301.212 bits (770), Expect = 1.449e-127
Identity = 206/516 (39.92%), Postives = 301/516 (58.33%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK--DQCYTLK----------TFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            +L+RG+SGGERKR NIGMELI DP V+FLDEPTTGLDA TA SV+  L+R+S  G+TIILSIHQP+YSIY+LFD  T++A G+ +YHG + SA L YF  +G+  EPHNNPADF++D++NG+                    + ES  EY E+             + D K+ ++ I ++L  +++    +KE + +L           +   +P   +ITY TS+ +Q KW+  RT  NL+ NPQT   Q+GV LF A +MG ++FG+  ++S   QNR G F F         L + E+FI    +F+HE  SGYYRVS Y  SK+LCD++ ++ FPAI+F  ITY+M G + +AGAFFFF L + +T     ++   +SA  SV  +AN+   I ++FM++FSG  +N+ SI  WLQW +YLS   + L  L  +E    + C T            +  +++   +G  FL   G  Y   W +WKN + L  +++  L + Y++LR + K+
Sbjct:  182 QLIRGISGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLSLLKRMSNHGRTIILSIHQPRYSIYRLFDSLTLLAGGRQVYHGPAQSA-LEYFSEIGFVCEPHNNPADFFLDVINGDST----------------AVIRESLQEYVELD-----------TEHD-KTSRQSIEQRLVEEYKSWSYYKETKEELEK----IMQGQNYSGKPKFHTITYNTSFCHQFKWVLKRTFRNLMLNPQTFYAQIGVSLFIALAMGAIFFGVSGDSS-GIQNRMGSFSFIITNQCLNALSSAELFITGHQLFLHEYVSGYYRVSVYLLSKILCDVLTLRTFPAIIFGCITYWMIGYKAEAGAFFFFMLSIAMTAYTATAMTMAISADQSVMDIANIFISISFIFMIIFSGLLVNLPSIVDWLQWIKYLSIPHYGLTALEASEFVGLEFCDTRSVSSGRPGFNASRESVTICTSGEEFLTEQGIDY-STWGMWKNIVALGCMTIILLSITYLKLRFIKKF 662          

HSP 2 Score: 177.178 bits (448), Expect = 1.449e-127
Identity = 87/144 (60.42%), Postives = 110/144 (76.39%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKK-YPWSKSVT-KIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            G+ +SFH I Y  + +  +   + VT K IL ++NG+M PG+NAI+G TGSGKSS LDVLA RKDPK L G+VLIDG PQP NFKC+SGYVVQDD+VMGTLTVREN  FSAALRL   +++ ++  KV  +I+ELGL+ VADS+
Sbjct:   35 GATVSFHKIHYAVEMRSGFLCKRKVTHKDILIDLNGIMKPGMNAILGATGSGKSSFLDVLAARKDPKGLTGEVLIDGAPQPPNFKCLSGYVVQDDVVMGTLTVRENFRFSAALRLPMSVSQKEKEEKVQRLIEELGLTKVADSR 178          
BLAST of ABC transporter domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007046.1 (pep scaffold:Pmarinus_7.0:GL476378:635185:650905:-1 gene:ENSPMAG00000006281.1 transcript:ENSPMAT00000007046.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 335.88 bits (860), Expect = 7.167e-143
Identity = 216/518 (41.70%), Postives = 306/518 (59.07%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEES----LNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQ--CYTLKTFPNISC---------YVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNK 2568
            EL+RGVSGGERKR NIGMELI DPSV+FLDEPTTGLDA TA +V+  L+R+SR G+TII SIHQP+YSI+KLFD  T++A G ++YHG S +A L+YF NLGY  EP+NNPADF++DI+NG+      + ++  S    H           EVK                + + + I E+L   +  S     N +ELR+      +     + A I   + S+TYATS+ +Q+ W+  R+  NL RNPQ S  QL V L     +G ++FG +++ S   QNR G  FF      F ++ AIE+FI+E+ IF HE  SGYYRVS+YF +K++ D++P++  PA VF  +TY+M G R  AG FF F L ++L +    S+A  +SA  SV  +AN++  I +VFM++FSG  +N+ S+  WL W +Y S  R+ L GL VNE +    C +  T  + +C           TG  +L R G      W LW+N + L  +++ FL + Y++LR + K
Sbjct:  184 ELIRGVSGGERKRTNIGMELINDPSVLFLDEPTTGLDASTANAVLLLLKRMSRKGRTIIFSIHQPRYSIFKLFDSLTLLASGSLVYHGPSKTA-LSYFQNLGYECEPYNNPADFFLDIINGDSTAVAAMRNENHSGEIEH---------EEEVK----------------QGEHRTIAEQLQEAYHNSDVYRANDEELRK------IFASVGSKASISIKTQSVTYATSFFHQLLWVTKRSVTNLSRNPQVSIAQLVVTLVLGLIVGAIFFGARLDPS-GIQNRVGSLFFITTNQCFSSVSAIELFIREKKIFTHEYISGYYRVSAYFLAKVMSDLIPMRTLPAAVFSIVTYWMIGNRATAGHFFIFMLTVVLVSYTATSMALAISAGQSVVAVANLLITICFVFMIIFSGLLVNLPSVMGWLNWLKYFSIPRYGLTGLQVNEFRGLMFCGSNHTSASFTCNSTSASTGAICTGEDYLCRQGI-GTNDWALWENLVALGCMTIIFLAITYLKLRFMRK 667          

HSP 2 Score: 191.045 bits (484), Expect = 7.167e-143
Identity = 104/187 (55.61%), Postives = 128/187 (68.45%), Query Frame = 2
Query:  506 PVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKK-YPWS-KSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            PV   ++M+P  D +NV    S   R S   L          +GSI+SFH+I+Y  K K   P   K + K IL N+NG+M PG+NAI+GPTG GKSS+LDVLA RKDP  LEG VL+DG PQP NFKC+SGYVVQDD+VMGTLTVREN EFSAALRL   I++ ++  +V  II+ELGL+  ADSK
Sbjct:    7 PVMAIVNMEP--DLDNVIK-RSISTRTSQRFL----------QGSILSFHNINYSVKQKSGLPCRRKVIVKEILKNINGIMKPGMNAILGPTGGGKSSLLDVLAARKDPNGLEGIVLVDGAPQPPNFKCVSGYVVQDDVVMGTLTVRENFEFSAALRLPQSISQQEKKERVNQIIQELGLAKCADSK 180          
BLAST of ABC transporter domain-containing protein vs. Ensembl Sea Lamprey
Match: abcg2b (ATP-binding cassette, sub-family G (WHITE), member 2b [Source:ZFIN;Acc:ZDB-GENE-050517-36])

HSP 1 Score: 227.639 bits (579), Expect = 5.080e-98
Identity = 143/352 (40.62%), Postives = 211/352 (59.94%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAG 2115
            +++RGVSGGERKRCNIGMELIT PSV+FLDEPTTGLDA TA ++I+ L RLSR+G+T+I SIHQP+YSI++ FDR T+M  G++++HG S  A + YF ++G +   H  P  F+        KN        ++  ++H     S  +  +V+R   S+ K G               +L   +    ++ + +R+L       E   +    P  I   YAT +  Q+  +C RT  N+LRNPQTS +Q  +   FA  +G++Y+ +  E     QNR G+FFF  + +VF NL A+E+F+ ER +F+HE+SSGYYR S+YF SK+  D++P ++ P ++F  I+YFM G
Sbjct:  159 DMIRGVSGGERKRCNIGMELITSPSVLFLDEPTTGLDANTATAIIRLLYRLSRNGRTVIFSIHQPRYSIFQNFDRLTLMHHGEVVFHGPSLDA-VPYFSSIGTNCGCH-LPLCFF----PARTKN--------MNRGKKHNG---SCDDDDDVERGEDSMEKGGS-------------LELAKAYRSCHHWADTQRRL-------EGIGNVAAVPVLIRSHYATRFHYQLYIVCGRTVKNMLRNPQTSFMQYFINTLFAVLVGLIYWQISDEPPAAIQNRMGVFFFLIINLVFANLSAVELFLYERVLFMHESSSGYYRTSAYFLSKVFADLLPNRIVPIVIFAAISYFMIG 473          

HSP 2 Score: 149.828 bits (377), Expect = 5.080e-98
Identity = 79/147 (53.74%), Postives = 106/147 (72.11%), Query Frame = 2
Query:  635 GSIISFHSISYKA-KSKKYPWS-KSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLE-GKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITK-----NDRSAKVTNIIKELGLSAVA 1051
            GS +S+  I Y   +   +P   K  TK+IL + +G+MLPG+NAIMGPTGSGK+S+LDVLAGRKDPK L+ G VL+DG P    F+ +SGYVVQDD++MGTL+VREN+EFSA LRL+ +  K      ++  +V N+I+ELGL+  A
Sbjct:    6 GSTLSYQGIIYSVNEGCGFPCRRKHETKMILRDHSGIMLPGMNAIMGPTGSGKTSLLDVLAGRKDPKGLKGGTVLLDGHPMDSGFRLISGYVVQDDVIMGTLSVRENIEFSANLRLAQQGAKRSDWEQEKQQRVDNVIRELGLTESA 152          
BLAST of ABC transporter domain-containing protein vs. Ensembl Sea Lamprey
Match: abcb10 (ATP-binding cassette, sub-family B (MDR/TAP), member 10 [Source:ZFIN;Acc:ZDB-GENE-040525-2])

HSP 1 Score: 48.521 bits (114), Expect = 4.139e-12
Identity = 24/83 (28.92%), Postives = 51/83 (61.45%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHG 1323
            +SGG+++R  I   ++ +P+++ LDE T+ LD+ + + V + L RL  +G+T+++  H  + S  +  DR  ++ +G++   G
Sbjct:  494 LSGGQKQRIAIARAILKNPNILLLDEATSALDSESESLVQEALDRL-MTGRTVLVIAH--RLSTIQGADRIAVLERGRVAQAG 573          

HSP 2 Score: 40.817 bits (94), Expect = 4.139e-12
Identity = 28/75 (37.33%), Postives = 45/75 (60.00%), Query Frame = 2
Query:  752 VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQ----PQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAA 964
            V A++GP+G GKS++L +L    DP+  +G+VLIDGQ      P   +   G V Q+ I+  + ++ EN+ + AA
Sbjct:  382 VTAVVGPSGCGKSTLLSLLLRLYDPQ--KGQVLIDGQDVREVNPSWLRSQIGTVSQEPILF-SCSIAENIAYGAA 453          
BLAST of ABC transporter domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001786.1 (pep scaffold:Pmarinus_7.0:GL477870:201625:214977:-1 gene:ENSPMAG00000001622.1 transcript:ENSPMAT00000001786.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.595 bits (109), Expect = 5.777e-10
Identity = 27/83 (32.53%), Postives = 45/83 (54.22%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHG 1323
            +SGG+++R  I   L+ DP V+ LDE T+ LDA +   V   L++ ++ G+T I+  H  + S  +  D   ++  G I   G
Sbjct:  384 LSGGQKQRVAIARALLRDPRVLLLDEATSALDAESEKVVQDALEK-AQQGRTCIVIAH--RLSTVRAADVIAVLQDGDICELG 463          

HSP 2 Score: 35.4242 bits (80), Expect = 5.777e-10
Identity = 30/113 (26.55%), Postives = 58/113 (51.33%), Query Frame = 2
Query:  716 ILNNVNGVMLPGVN-AIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDG----QPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTR--ITKNDRSAKVTNIIKEL 1033
            +L  V+  + PG   A++GP+GSGKS+I+ +L    D     G++L++G    Q      +   G V Q+ ++ G  ++ EN+ +    R  +R  +    R+A + + ++ L
Sbjct:  260 VLRGVSLRVAPGQTLALVGPSGSGKSTIMQLLLRFYDSS--AGQLLLNGVEVRQLNLGWLRRQLGVVSQEPVLFGC-SIAENIAYGDVSRAVSRDEVVAAARAANLHDFVESL 369          
BLAST of ABC transporter domain-containing protein vs. Ensembl Sea Lamprey
Match: ABCB1 (ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40])

HSP 1 Score: 44.2838 bits (103), Expect = 1.139e-9
Identity = 22/59 (37.29%), Postives = 37/59 (62.71%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQ 1251
            +SGG+++R  I   LI +P ++ LDE T+ LD  + A V + L + +R G+T I+  H+
Sbjct:  317 LSGGQKQRIAIARALIRNPKLLLLDEATSALDGESEAIVQEALDK-AREGRTTIVIAHR 374          

HSP 2 Score: 36.965 bits (84), Expect = 1.139e-9
Identity = 28/106 (26.42%), Postives = 56/106 (52.83%), Query Frame = 2
Query:  680 KKYPWSKSVTKIILNNVNGV-MLPGVN---------AIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQ----PQPKNFKCMSGYVVQDDIVMGTLTVRENLEF 955
            K+  W +  T  ++N++    +L GVN         A++G +G GKS+ + +L    DP+  +G +++DG+       ++ + + G V Q+ ++  T T+ EN+ F
Sbjct:  176 KRCTWFREHT--LVNSIAFCQVLKGVNLQVKSGQTVALVGSSGCGKSTTIQLLQRFYDPQ--QGTIMVDGRDVRTLNLRSLRQLIGVVSQEPVLFAT-TIAENIRF 276          

HSP 3 Score: 49.6766 bits (117), Expect = 4.072e-6
Identity = 26/83 (31.33%), Postives = 46/83 (55.42%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHG 1323
            +SGG+++R  I   L+  P ++ LDE T+ LD  +   V + L R +R G+T I+  H  + S  +  D+  ++  G++I  G
Sbjct:  959 LSGGQKQRIAIARALVRQPKILLLDEATSALDTESEKIVQEALDR-AREGRTCIVIAH--RLSTVQTADKIAVIQNGQVIEQG 1038          
BLAST of ABC transporter domain-containing protein vs. Ensembl Yeast
Match: ADP1 (Putative ATP-dependent permease of the ABC transporter family [Source:SGD;Acc:S000000604])

HSP 1 Score: 149.443 bits (376), Expect = 1.195e-53
Identity = 116/382 (30.37%), Postives = 194/382 (50.79%), Query Frame = 1
Query: 1057 QELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRS-GKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDIL-----NGEVKNEKEILDQQISYSRR------HIAVLESS------------GEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYD-WEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISI-TYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRL 2124
             E  RG+SGGE++R +I  EL+T P V+FLDEPT+GLDA  A +VI+ L RLS    +T++LSIHQP+ +I+ LFD+  +++KG+++Y G +      +  N GY    + N AD+ IDI       G+ +  + I D +            H     SS                E++ +L     V        + +  +  KL +D +++S+ + EL +++   +V++E D ++ +    +     +  +  Q+  L  R+  N+ RNP+       + +  +  +G +Y+ +  + S   QNR GLFFF      FV    +  F  ER IFI E S+ YY   +Y+ SK++ ++VP++V P I+   I Y M GL +
Sbjct:  524 NEFDRGISGGEKRRVSIACELVTSPLVLFLDEPTSGLDASNANNVIECLVRLSSDYNRTLVLSIHQPRSNIFYLFDKLVLLSKGEMVYSGNAKKVS-EFLRNEGYICPDNYNIADYLIDITFEAGPQGKRRRIRNISDLEAGTDTNDIDNTIHQTTFTSSDGTTQREWAHLAAHRDEIRSLLRDEEDVEGTDGRRGATEIDLNTKLLHDKYKDSVYYAELSQEIE--EVLSEGDEESNVLNGDLPTGQQSAGFLQQLSILNSRSFKNMYRNPKLLLGNYLLTILLSLFLGTLYYNVSNDIS-GFQNRMGLFFFILTYFGFVTFTGLSSFALERIIFIKERSNNYYSPLAYYISKIMSEVVPLRVVPPILLSLIVYPMTGLNM 901          

HSP 2 Score: 79.337 bits (194), Expect = 1.195e-53
Identity = 46/134 (34.33%), Postives = 83/134 (61.94%), Query Frame = 2
Query:  638 SIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQP-KNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKEL 1033
            + +SF +I+Y   S     S  V + +LN ++G++ PG + AIMG +G+GK+++LD+LA ++   ++ G + ++G     K+F  + G+V QDD ++ TLTV E +  SA LRL   ++   + A+V  +++EL
Sbjct:  382 ATLSFENITYSVPSIN---SDGVEETVLNEISGIVKPGQILAIMGGSGAGKTTLLDILAMKRKTGHVSGSIKVNGISMDRKSFSKIIGFVDQDDFLLPTLTVFETVLNSALLRLPKALSFEAKKARVYKVLEEL 512          
BLAST of ABC transporter domain-containing protein vs. Ensembl Yeast
Match: YOL075C_mRNA (Putative ABC transporter [Source:SGD;Acc:S000005435])

HSP 1 Score: 118.627 bits (296), Expect = 4.326e-45
Identity = 53/130 (40.77%), Postives = 92/130 (70.77%), Query Frame = 1
Query: 1057 QELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSR-SGKTIILSIHQPKYSIYKLFDRYTIMAK-GKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEK 1440
             E ++G+SGGE++R  +G++L+ DP ++ LDEPT+GLD+FT+A++++ L++L R  GKTII++IHQP+  ++K F    ++AK G+  ++G S    + YF  LGY+     N ADF++D+++   +NE+
Sbjct:  833 NEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLCREQGKTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNG-SPDEMIAYFTELGYNCPSFTNVADFFLDLISVNTQNEQ 961          

HSP 2 Score: 81.2629 bits (199), Expect = 4.326e-45
Identity = 50/119 (42.02%), Postives = 74/119 (62.18%), Query Frame = 2
Query:  707 TKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLE-----GKVLI-DGQPQPKNFKCMSGYVVQ-DDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGL 1039
            TK IL +VN +  PG +NAIMGP+GSGKSS+L++++GR            G ++  D Q     FK +  YV Q DD ++  LTV+E L+++AALRL   +T+ +R  +  N+I+ LGL
Sbjct:  706 TKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSIMFNDIQVSELMFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLH-HLTEAERMERTDNLIRSLGL 823          

HSP 3 Score: 130.954 bits (328), Expect = 3.581e-41
Identity = 64/155 (41.29%), Postives = 105/155 (67.74%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRS-GKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKE----------ILDQQISYSRRHIAVLESS 1500
            RG+SGGE++R +IG ++I++PS++FLDEPTTGLDA++A  VIKTL++L++  G+T I+SIHQP+  I  L D+  I++KG ++Y  K  +  + YF ++GYH+    NPAD++ID+ + + +++KE          ++D    Y R H+ +   S
Sbjct:  184 RGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKLAKEDGRTFIMSIHQPRSDILFLLDQVCILSKGNVVYCDKMDNT-IPYFESIGYHVPQLVNPADYFIDLSSVDSRSDKEEAATQSRLNSLIDHWHDYERTHLQLQAES 337          

HSP 4 Score: 55.8398 bits (133), Expect = 3.581e-41
Identity = 44/139 (31.65%), Postives = 69/139 (49.64%), Query Frame = 2
Query:  707 TKIILNNVNGVMLPG--VNAIMGPTGSGKSSILDVLAGR-------------------KDPKYLEGK-VLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADS 1057
            T   L N   + LP   V A+MG +GSGK+++L+VLA +                    +P   E K   +DGQ  P     +  Y+ Q D++   LT RE L+F+A L+L++  ++  +   V  +I+ELGL   AD+
Sbjct:   40 TNTTLVNTFSMDLPSGSVMAVMGGSGSGKTTLLNVLASKISGGLTHNGSIRYVLEDTGSEPNETEPKRAHLDGQDHPIQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNS--SERTKKLMVEQLIEELGLKDCADT 176          
BLAST of ABC transporter domain-containing protein vs. Ensembl Yeast
Match: PDR5 (Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth; PDR5 has a paralog, PDR15, that arose from the whole genome duplication [Source:SGD;Acc:S000005679])

HSP 1 Score: 88.5817 bits (218), Expect = 1.073e-37
Identity = 48/121 (39.67%), Postives = 76/121 (62.81%), Query Frame = 2
Query:  698 KSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADS 1057
            K+ T+ ILNNV+G + PG + A+MG +G+GK+++LD LA R     + G +L++G P+ K+F    GY  Q D+ + T TVRE+L FSA LR    ++  +++  V  +IK L +   AD+
Sbjct:  881 KAETRRILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITGDILVNGIPRDKSFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQPAEVSIEEKNRYVEEVIKILEMEKYADA 1001          

HSP 2 Score: 86.2705 bits (212), Expect = 1.073e-37
Identity = 45/123 (36.59%), Postives = 76/123 (61.79%), Query Frame = 1
Query: 1072 GVSGGERKRCNIGMELITDPSV-IFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAK-GKIIYHGKSGSAP---LNYFHNLGYHIEPHN-NPADFYIDILNG 1422
            G++  +RKR  IG+EL   P + +FLDEPT+GLD+ TA S+ + +++L+  G+ I+ +IHQP   + + FDR   M + GK +Y G  G      ++YF + G H  P + NPA++ ++++  
Sbjct: 1009 GLNVEQRKRLTIGVELTAKPKLLVFLDEPTSGLDSQTAWSICQLMKKLANHGQAILCTIHQPSAILMQEFDRLLFMQRGGKTVYFGDLGEGCKTMIDYFESHGAHKCPADANPAEWMLEVVGA 1131          

HSP 3 Score: 65.4698 bits (158), Expect = 3.684e-11
Identity = 39/119 (32.77%), Postives = 60/119 (50.42%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSR-SGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDI 1413
            +++RGVSGGERKR +I    I        D  T GLD+ TA   I+ L+  +  S  +  ++I+Q     Y LF++  ++  G  IY+G +  A   YF ++GY        ADF   +
Sbjct:  304 DIVRGVSGGERKRVSIAEVSICGSKFQCWDNATRGLDSATALEFIRALKTQADISNTSATVAIYQCSQDAYDLFNKVCVLDDGYQIYYGPADKAK-KYFEDMGYVCPSRQTTADFLTSV 421          
BLAST of ABC transporter domain-containing protein vs. Ensembl Yeast
Match: PDR12 (Plasma membrane ATP-binding cassette (ABC) transporter; weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity [Source:SGD;Acc:S000005979])

HSP 1 Score: 87.0409 bits (214), Expect = 2.150e-36
Identity = 45/124 (36.29%), Postives = 80/124 (64.52%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVI-FLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAK-GKIIYHGKSG---SAPLNYFH-NLGYHIEPHNNPADFYIDILNG 1422
            RG++  +RK+ +IG+EL+  PS++ FLDEPT+GLD+ +A S+++ ++ L+ SG++I+ +IHQP  ++++ FDR  ++ K GK++Y G  G      L YF    G       NPA++ ++ +  
Sbjct:  981 RGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSILCTIHQPSATLFEQFDRLLLLKKGGKMVYFGDIGPNSETLLKYFERQSGMKCGVSENPAEYILNCIGA 1104          

HSP 2 Score: 83.5741 bits (205), Expect = 2.150e-36
Identity = 49/152 (32.24%), Postives = 87/152 (57.24%), Query Frame = 2
Query:  605 NVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADS 1057
            NVD  K   +  + +++ + Y       P+  + T+ +L++V G + PG + A+MG +G+GK+++L+VLA R +   + G +L++ +P P +F    GYV Q D  M  L+VRE+L F+A LR  + +   ++   V  II  LG+   A++
Sbjct:  829 NVDLEKVIAEKDVFTWNHLDYTI-----PYDGA-TRKLLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGVITGDMLVNAKPLPASFNRSCGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEA 974          

HSP 3 Score: 70.0922 bits (170), Expect = 1.364e-12
Identity = 51/155 (32.90%), Postives = 80/155 (51.61%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTA---ASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSE 1515
            + +RGVSGGERKR ++      + S+   D  T GLDA TA   A  I+T   +  +  + I++I+Q   +IY+LFD+ T++  G+ IY G +  A + YF  +G+        A+F   +    V  E   LD +  Y  +   V +SS E+ E
Sbjct:  291 DFVRGVSGGERKRVSLVEAQAMNASIYSWDNATRGLDASTALEFAQAIRTATNMVNN--SAIVAIYQAGENIYELFDKTTVLYNGRQIYFGPADKA-VGYFQRMGWVKPNRMTSAEFLTSV---TVDFENRTLDIKPGYEDK---VPKSSSEFEE 436          
BLAST of ABC transporter domain-containing protein vs. Ensembl Yeast
Match: PDR10 (ATP-binding cassette (ABC) transporter; multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p [Source:SGD;Acc:S000005855])

HSP 1 Score: 88.5817 bits (218), Expect = 3.015e-36
Identity = 52/159 (32.70%), Postives = 87/159 (54.72%), Query Frame = 1
Query: 1072 GVSGGERKRCNIGMELITDPSV-IFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAK-GKIIYHGKSGSAP---LNYFHNLGYH-IEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRML 1530
            G++  +RKR  IG+EL   P + +FLDEPT+GLD+ TA S  + +++L+  G+ I+ +IHQP   + + FDR   + + G+ +Y G+ G      +NYF   G H   P  NPA++ ++I+                 S+ + A+   S EY E+++ L
Sbjct: 1063 GLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLDSQTAWSTCQLMKKLASRGQAILCTIHQPSALLMQEFDRLLFLQEGGQTVYFGELGKGCKTMINYFEAHGAHKCPPDANPAEWMLEIVGAAPGTHA---------SQDYFAIWRDSEEYREMQKEL 1212          

HSP 2 Score: 81.6481 bits (200), Expect = 3.015e-36
Identity = 44/121 (36.36%), Postives = 75/121 (61.98%), Query Frame = 2
Query:  698 KSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADS 1057
            K+  + IL+NV+G + PG + A++G +G+GK+++LD LA R     + G V +DG+P+ ++F    GY  Q D+ + T TVRE+L FSA LR +  ++  ++   V  +I+ L +   AD+
Sbjct:  935 KNGKRRILDNVDGWVKPGTLTALIGASGAGKTTLLDCLAERTTMGLITGDVFVDGRPRDQSFPRSIGYCQQQDLHLKTATVRESLRFSAYLRQADDVSIEEKDKYVEEVIEVLEMKLYADA 1055          

HSP 3 Score: 68.9366 bits (167), Expect = 3.492e-12
Identity = 85/362 (23.48%), Postives = 146/362 (40.33%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQ---RLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILN-GEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIF--IKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLD 2127
            + +RGVSGGERKR +I    I        D  T GLD+ TA   IK L+    +++S  T+  +I+Q     Y LFD+  ++  G  I+ G S  A   YF  +GY        AD+   I +  E   +K+++   I   +    + +   +  E K++ + V+K       L +D                   + R Q+    +  +       RP S    Y  S+  Q+K++  R    +  +P      +  +   A  +G +++ + M ++      +         +       +EIF   + RPI     +   YR S+  F+    D VP K+  A+ F    YF+  L+ D
Sbjct:  324 DFVRGVSGGERKRVSIAEVSICGSKFQCWDNATRGLDSATALEFIKALKTQATITKSAATV--AIYQCSKDAYDLFDKVCVLYDGYQIFFGPSKQAK-KYFQRMGYVCPERQTTADYLTSITSPSERIKDKDMVKHGIMIPQTAYEMNQYWIQSEEYKQLQVQVNK------HLDTDS-----------------SQQREQIKNAHIAKQSK---RARPSS---PYTVSFFLQVKYILIRDIWRIKNDPSIQLFTVLSHAAMALILGSMFYEV-MLSTTTTTFYYRGAAIFFAILFNAFSSLLEIFSLYETRPITEKHKTYSLYRPSADAFASTFSD-VPTKLATAVTFNIPYYFLINLKRD 651          
BLAST of ABC transporter domain-containing protein vs. Ensembl Nematostella
Match: EDO42968 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S071])

HSP 1 Score: 262.692 bits (670), Expect = 1.072e-117
Identity = 172/432 (39.81%), Postives = 256/432 (59.26%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFAL 2355
            E +RGVSGGERKR +IGMELIT PSV+FLDEPTTGLDA TA +VI+ L  L R GKTII SIHQP+YSI+KLFD   +++ G ++Y G +  A L YF  +GY  E HNNP DF++D++N    N+  +                         +     S+  RPK+          + + + +++       + +   + +I E  + +  +   I ++Y+ S + Q +++  R   NL R+      Q+   + FA  +G +Y+  + +     QNR G FFF  + +VF NL A+E+FIKER IF+HE++ GYYRVS+YF +K+LCD++P+++ P   F  I YFM G + +   FF F L L+LT+   C ++FFVSAS   F +AN++  + YVFMMVFSG  +N+ S+ +WL W +Y+S FR+A+
Sbjct:  150 EFIRGVSGGERKRTSIGMELITSPSVLFLDEPTTGLDASTACTVIRLLHTLGRRGKTIIFSIHQPRYSIFKLFDSMILLSVGDMVYQGLASDA-LVYFDKIGYSCEAHNNPPDFFMDVINA---NQGAV--------------------SGSTGKPGGGGSEPARPKN----------QSVPHLFKD-------KTKTTCHCLINERKSFSNPKKSQIKMSYSQSLAVQTRFIRTRGDKNLPRS------QMFTMVIFAVIVGAIYYN-QTDGPSGLQNRVGAFFFIVMNMVFGNLSAVELFIKERKIFMHESAGGYYRVSAYFLAKVLCDIIPMRLIPISGFSAIVYFMIGFKREVLKFFIFLLTLVLTSLCACGLSFFVSASVETFAIANLLIALPYVFMMVFSGVLVNLGSVGAWLSWIKYISIFRYAV 533          

HSP 2 Score: 181.03 bits (458), Expect = 1.072e-117
Identity = 86/142 (60.56%), Postives = 110/142 (77.46%), Query Frame = 2
Query:  635 GSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            GS+ISFH ISY  ++  +     + K ILN ++G+M PGVNAI+GPTGSGK+++LDVLAGRKDP  L G VLIDG+ QP+NFKC+SGYVVQDD+VMGTLT+RENL FSA LRL   ++K DR  +V   +++LGL+ VAD K
Sbjct:    7 GSVISFHEISYTVRT--FHNGLKIDKDILNQISGIMKPGVNAILGPTGSGKTTLLDVLAGRKDPHCLTGTVLIDGRLQPENFKCISGYVVQDDVVMGTLTIRENLNFSACLRLPRTLSKKDREQRVNETVRDLGLTEVADQK 146          
BLAST of ABC transporter domain-containing protein vs. Ensembl Nematostella
Match: EDO41448 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4C3])

HSP 1 Score: 145.976 bits (367), Expect = 2.197e-54
Identity = 142/506 (28.06%), Postives = 231/506 (45.65%), Query Frame = 1
Query: 1033 RIIRSCG*QELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLS-RSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSIS--------------------ITYATSWSNQMKWLCWRTAMNLLRNPQT-STIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKD----QCYTLKTFPNI--SCYVTGNVFLDRNGFY 2466
            + + +C    + RG+SGGE+KR NIG ELI +PS+IFLDEPT+GLD+  A ++IKTLQ    +  KTI+ SIHQP   IY LFD+  ++  G++ Y+GK+ S  L +F ++     PH NPADF              IL++  + S     ++ES  +  E K ++   S      S L     VI        +  +  ++L R  +    +T++ T    +  ++S                      + TS+  Q   L  RT       P+  S +        +  +G+++F +             +FF      +     A+  F  ER I   E ++GYYR+S+Y+F+KL  ++ P+ V   I F+ + Y+M GL  ++ AF     +LLLT+    S+   +SAS   F     V  I  + MM+  G++     I  WL+W +YLS   +   G  + E       +C  +  + +     ++TG   L   G +
Sbjct:  132 KCLHTCIGSPMERGLSGGEKKRANIGCELIINPSLIFLDEPTSGLDSSNAMNLIKTLQDYCLKEKKTIVTSIHQPSSQIYHLFDKLLLLCNGQMAYYGKA-SKVLEFFESINLICAPHFNPADF--------------ILEKVTAGSEVENRIVESWAKRREKKNLMNEASPDTHTSSKLNG---VINGSAIKQEDHKVKNRDLHRPNSHSKKLTDEVTLVSFKKTAVSDVKLNVDDDNDDDDDYTDVHTGWVTSFWTQFTVLTERTFKQ--SKPEILSKLNFIQTFVLSIIVGLIWFRIPYTEETIRDRYAVVFFVIVYWNLNPMFSALVSFPAERTIINKERAAGYYRLSAYYFAKLFSEL-PLVVCQPIGFMLVAYWMCGLN-ESVAFLTHLSVLLLTSITAQSIGLCISASIMDFKKCITVAAIFGLTMMLLGGFYQQ--HIPWWLEWFEYLSFMTYTYRGCVIAEFATSPPFRCSEVSAYASCKNGTWITGTEVLHELGIH 613          

HSP 2 Score: 86.2705 bits (212), Expect = 2.197e-54
Identity = 52/112 (46.43%), Postives = 72/112 (64.29%), Query Frame = 2
Query:  716 ILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGR--KDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLS 1042
            IL  +NG + PG + A+MGP+GSGK+++L+VLAGR  KD     G VLI+G+   K  K   GYV+Q+DI    LT++E L +SA LRL   ++K  +  KV  I+K L LS
Sbjct:   24 ILKTINGKVRPGEMLALMGPSGSGKTTLLNVLAGRMAKDA----GDVLINGKHMNKKLKKRIGYVMQEDIFFSHLTLKETLTYSAMLRLPDTLSKAQKLQKVDEIVKILDLS 131          
BLAST of ABC transporter domain-containing protein vs. Ensembl Nematostella
Match: EDO43923 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX93])

HSP 1 Score: 122.479 bits (306), Expect = 2.590e-44
Identity = 55/129 (42.64%), Postives = 86/129 (66.67%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQ 1455
            RG+SGGE+KR +   E++TDPS++F DEPT+GLD+F A SV+ TLQ+L+  G+TII +IHQP   +Y +F    ++A+G+  Y G +    + +F +LGY   P+ NPAD+++  L     + +  LD+
Sbjct:  124 RGISGGEQKRLSFASEILTDPSILFADEPTSGLDSFMAQSVVATLQKLAAQGRTIICTIHQPSSEVYNMFSSLLLVAEGRTAYFGLTRDV-IPHFSSLGYPCPPNYNPADYFVHTLAVVPDDRQNCLDR 251          

HSP 2 Score: 76.2554 bits (186), Expect = 2.590e-44
Identity = 46/115 (40.00%), Postives = 71/115 (61.74%), Query Frame = 2
Query:  719 LNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRK-DPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADS 1057
            L +V+G + PG + A+MG +GSGK+++++VLA R     ++ G V  + +        +S Y+ Q+D+ +GTLTVRE+L+F A LR+   I   +R  KV  +I ELGL   ADS
Sbjct:    1 LLSVSGKVNPGELVAVMGASGSGKTTLINVLAHRNIGSMHVSGVVKANNKTLGLAINSISAYIQQEDLFIGTLTVREHLKFQALLRIDKHIPDRERMEKVEEVISELGLVKCADS 115          

HSP 3 Score: 67.3958 bits (163), Expect = 1.404e-11
Identity = 57/221 (25.79%), Postives = 101/221 (45.70%), Query Frame = 1
Query: 1714 SITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNE 2376
            +I Y  SW  Q K + WR+ ++  R+     I++   +F     G+VY    ++A         LFF               +F  E P+F+ ++ +G YR   YF  K L ++ PI +    +   I Y+M GL+ +   F    ++L+L T    S+ + +S        A  + P I V  ++F G+F+  +SI  +  W +Y S F+++   L +N+
Sbjct:  277 TIPYKASWWRQFKTVMWRSWLSNRRDVLMFRIRILQSIFMGLLAGLVYLQTNIDADSIQNISGALFFLITTLAFSSLQAVYFVFPIELPVFLRDHKNGMYRTDVYFLCKTLTEL-PIFIISPFLISVIPYWMIGLQSEFTRFLICFVVLMLVTNTAVSIGYMISTMMKSTAAAGAIGPPILVPFLLFGGFFLKSTSIPVYFVWIEYTSFFKYSFELLSINQ 496          
BLAST of ABC transporter domain-containing protein vs. Ensembl Nematostella
Match: EDO42362 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1R2])

HSP 1 Score: 117.087 bits (292), Expect = 6.974e-41
Identity = 52/120 (43.33%), Postives = 82/120 (68.33%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGK-TIILSIHQPKYSIYKLFDRYTIMA-KGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNG 1422
            RG+SGG+RKR NIGMEL+ DP+++FLDEPT+GLD+ ++ SV+  L+ ++  G+ TI+  IHQP++ I+++F     +   G+ ++ G    A   YF  LG+    + NPADFY+D++ G
Sbjct:  129 RGISGGQRKRVNIGMELVVDPTLLFLDEPTSGLDSTSSLSVLNALRAVAERGRLTIVCVIHQPRFEIFRMFHNLLFLGPGGRTVFQGSVDKAE-EYFQRLGFEKPLNVNPADFYMDVIGG 247          

HSP 2 Score: 70.0922 bits (170), Expect = 6.974e-41
Identity = 40/120 (33.33%), Postives = 73/120 (60.83%), Query Frame = 2
Query:  710 KIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPK--NFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K +L  V G +  G V A+MGP+G+GK++ L+ L+G+       G++ I+G+ +     ++ ++G+V Q+D++   LTV+E L + A LRLS+ + K  +  ++  II+ L L  + DS+
Sbjct:    3 KTVLMGVTGKIKSGEVTAVMGPSGAGKTTFLNTLSGKAYYGTRGGEIFINGKKEDDLDMYRTITGFVPQEDVMHRNLTVKEVLRYQAELRLSSIVKKAMKEERIHQIIELLELERIQDSQ 122          
BLAST of ABC transporter domain-containing protein vs. Ensembl Nematostella
Match: EDO49953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7REQ2])

HSP 1 Score: 114.39 bits (285), Expect = 8.177e-38
Identity = 51/118 (43.22%), Postives = 81/118 (68.64%), Query Frame = 1
Query: 1069 RGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGK-TIILSIHQPKYSIYKLFDRYTIMA-KGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDIL 1416
            RG+SGG+RKR NIGMEL+ DP+++FLDEPT+GLD+ ++ SV+  L+ ++  G+ TI+  IHQP++ I+++F     +   G+ ++ G    A   YF  LG+    + NPADFY+D++
Sbjct:  127 RGISGGQRKRVNIGMELVVDPTLLFLDEPTSGLDSTSSLSVLNALRAVAEKGRLTIVCVIHQPRFEIFRMFHNLLFLGPGGRTVFQGSVDEAE-EYFQCLGFEKPLNVNPADFYMDVI 243          

HSP 2 Score: 62.7734 bits (151), Expect = 8.177e-38
Identity = 40/120 (33.33%), Postives = 70/120 (58.33%), Query Frame = 2
Query:  710 KIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPK--NFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            K +L  V G +  G V A+MGP+G+GK++ L+ L+G+       G + I+G  +     ++ ++G+V Q+D++   LTV+E L + A LRLS+    + +  +V  II+ L L  + DS+
Sbjct:    1 KKVLAGVTGKINSGEVTAVMGPSGAGKTTFLNTLSGKAYYGNRGGDIFINGVKESDFDKYRTITGFVPQEDVMHRNLTVKEVLRYQAELRLSSSTKSSKKHERVQQIIELLQLERIQDSQ 120          
BLAST of ABC transporter domain-containing protein vs. Ensembl Medaka
Match: abcg2d (ATP-binding cassette sub-family G member 2-like [Source:NCBI gene;Acc:101170649])

HSP 1 Score: 318.161 bits (814), Expect = 5.232e-134
Identity = 206/522 (39.46%), Postives = 298/522 (57.09%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLK---SDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEM------KDQCYTLKTFPN--ISCYV-------TGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            ++ RG+SGGERKR +IGMELI DP+V+FLDEPTTGLDA TA SV+  L+R++  G+TII+SIHQP+YSIY+LFD  T++  GK++YHG + +A L+YF N+GY  EPHNNPADF++D++NG+                   A   + G  SE              + D +   S ++ I E L  ++  S    + R +L       E ++  + R     ITY +S++ Q++W+  RT  NL+ NPQTS  QL V +F AF +G ++FG+K + S   QNR G  FF      F  + A E+FI ER +F+HE  SGYYRVS YF SK+L D + ++   +++F  I YF+ GL+    AF  F L + L      ++   +SA  SV  LAN++  I +VFMM+FSG  +N+ SI  WL W +Y S  R+ L  L +NE       ++    L       I+C V       TG  +LD  G  Y   W LW+N + L ++ + FLI+ Y++LR + K+
Sbjct:  184 QMTRGISGGERKRTSIGMELIIDPAVLFLDEPTTGLDASTANSVLLLLKRMASHGRTIIMSIHQPRYSIYRLFDSLTLLVSGKMVYHGPAPNA-LDYFANIGYSCEPHNNPADFFLDVINGDFT-----------------ATTSTKGHNSE--------------ELDFEMWSSARRNIKEHLVAEYRSSSYCSDTRAELKRISQNKECNSQTKSRI----ITYNSSFAQQLRWVLQRTFQNLMLNPQTSVAQLTVNIFLAFIVGAIFFGVKDDQS-GIQNRMGALFFITTNQCFSTVSAAELFISERKLFVHEYISGYYRVSVYFLSKILSD-ITMRTVTSLIFSLIVYFIIGLKSTVAAFLIFTLTVTLVAYTATAMTMAISADQSVVALANILMTITFVFMMIFSGLLVNLPSIMDWLAWLKYFSIPRYGLAALKINEFVGLKFCEEHIIQLANSSAGIINCTVTTAGQTCTGEQYLDYLGIEY-SSWGLWENHVALTVMMVIFLIVAYLKLRFIQKF 666          

HSP 2 Score: 181.415 bits (459), Expect = 5.232e-134
Identity = 90/152 (59.21%), Postives = 114/152 (75.00%), Query Frame = 2
Query:  611 DHRKTPTKGSIISFHSISYKAKSKKYPWS--KSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            D  + P  GS +SFH++ YK + K  P    K     IL ++NG+M PG+NAI+GPTGSGKSS LD+LA RKDP  L G+VLIDG PQP NFKC+SGYVVQ+DIVMGTLTVRENL FSAALRL   +++ ++  +V +++KELGL+ VADSK
Sbjct:   30 DWNQQPC-GSTVSFHNVHYKVQLKSGPICQRKMNPMQILMDLNGIMRPGLNAILGPTGSGKSSFLDILAARKDPIGLSGEVLIDGAPQPPNFKCLSGYVVQEDIVMGTLTVRENLRFSAALRLPGSVSQREKEVRVNHLLKELGLTKVADSK 180          
BLAST of ABC transporter domain-containing protein vs. Ensembl Medaka
Match: abcg2c (ATP-binding cassette sub-family G member 2 [Source:NCBI gene;Acc:101164130])

HSP 1 Score: 345.51 bits (885), Expect = 2.774e-130
Identity = 220/506 (43.48%), Postives = 306/506 (60.47%), Query Frame = 1
Query: 1060 ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDD-TDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            E LRGVSGGERKRC+IGMELIT PS++FLDEPTTGLD+ TA  +I  L +L+R GKT+I SIHQP+YSI+K FD  T+M KG+++Y G +  A L+YF NLGY IE  NNPADF++DI NGE+           S +  HI      GE S+                          + L+  + +S  +K ++ +L   +   E+D  D E         YATS+  QM+ +C RT  N+LRNPQTS  QL + +FFA  +G++Y+ + +      QNR G FFF  + +VF NL A+E+FI ER IFIHENSSGYYR S YF SK+  D++P ++ P +VF  I Y+M GL+     F  F LI+ L + AG  +AF VSAS S F +AN++  + +VFMMVF GY +N++++  WL W +++S FR+ L    +NEMK Q +    + N + +  G ++L   G  Y   W  W+N + L  I +  +IL YVQLRR+N++K
Sbjct:  168 EFLRGVSGGERKRCSIGMELITSPSLLFLDEPTTGLDSNTANCIIGLLHKLARRGKTVIFSIHQPRYSIFKQFDHLTLMHKGEVVYAGAAAQA-LDYFTNLGYQIEAFNNPADFFMDITNGEIT----------STAALHI------GEKSQ--------------------------KSLSEKYRQSQLYKIMKEELEHINKSIENDGVDKE------KAGYATSFLYQMRVVCGRTVRNILRNPQTSYAQLALQIFFAILVGLIYYQMPLTLPEALQNRSGAFFFLIINMVFGNLSAVELFINERAIFIHENSSGYYRTSVYFLSKIFADLIPNRIIPILVFSAIAYYMMGLKPAFENFICFALIMSLVSLAGVGLAFLVSASVSTFAMANILIALPFVFMMVFGGYLVNLNAMLDWLSWLKWISIFRYGLNAAFINEMKGQVF----YSNNTIF-PGELYLVSLGLDY-SVWGFWQNIVALLGIIIICMILAYVQLRRINRWK 618          

HSP 2 Score: 141.739 bits (356), Expect = 2.774e-130
Identity = 77/158 (48.73%), Postives = 107/158 (67.72%), Query Frame = 2
Query:  593 DSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYL-EGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTR-ITKNDRSAKVTNIIKELGLSAVADSK 1060
            D + ++D   +  +G  I+F ++ Y  + K +       K IL +V+G+M PG+NAIMG TGSGK+S+LDV+AGRKDP  L +G+VL+DGQ      +  S YVVQDDI+MGTLTVRENL FSA LRL+ +  +  D++ +V  II ELGL+  AD+K
Sbjct:    7 DRVTSIDEESSHERGPTITFSNLHYSVQEKTFCRKTGPEKHILKDVSGIMKPGMNAIMGATGSGKTSLLDVIAGRKDPAGLRQGQVLVDGQVVTSELRLSSAYVVQDDILMGTLTVRENLLFSANLRLNPKHHSSTDKNNRVNIIINELGLTDCADTK 164          
BLAST of ABC transporter domain-containing protein vs. Ensembl Medaka
Match: abcg2a (ATP-binding cassette sub-family G member 2-like [Source:NCBI gene;Acc:101167488])

HSP 1 Score: 317.005 bits (811), Expect = 1.559e-95
Identity = 219/535 (40.93%), Postives = 310/535 (57.94%), Query Frame = 1
Query: 1003 RQGDKHYQRV-------RIIRSCG*QELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMK--DQCYTLK---TFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKY 2571
            ++ DK   RV       R+  S    +L+RG+SGGERKR NIGMELI DP V+FLDEPTTGLDA TA SV+  L+R+  +G+ IILSIHQP+YSIY+LFD  T++  GK +YHG + SA L+YF ++G+  E HNNPADF++D++NG+  +    L+   S         E      +++R   SVS            +K I +KL  ++  S ++++ + +L   D I +      +   S +ITY T +  Q KW+  RT  NL  NPQTS  Q+ V LF A  +G ++F +K + S   QNR G  FF      F +L A E+FI ER +F HE  SGYYRVS YF SK+L D++ ++  PAIVF  + YFM GL+  A AFF F   + +      ++A  +SA  +V  +AN+   I  VFMM+F+G  +N+ SI SWL W +YLS  R+    L  NE    + C  L    T P ++C  TG  FLD+ G  +   W LW+N L L +++L FL + Y++LR + K+
Sbjct:  149 KEKDKMVDRVIQELGLGRVADSKVGTQLIRGISGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLLLLKRMGNNGRNIILSIHQPRYSIYRLFDSLTLLVNGKQVYHGPARSA-LDYFSDMGFTCEAHNNPADFFLDVINGD--STAVALNNADS---------EDPDPDPDLRRDPDSVSM----------SRKGIEDKLVEEYRSSQHYRQTKAEL---DRIVQGKQGMTV-SRSRTITYNTGFLTQFKWVLKRTFRNLALNPQTSVAQVAVTLFLALIVGALFFDVKEDQS-GIQNRAGALFFIVTNQCFSSLSAAELFITERKLFTHEYISGYYRVSVYFLSKILSDILVMRTIPAIVFSCVAYFMIGLKPTAEAFFTFLFSVAMVAYTATAMAMAISADQTVVAIANIFMTIACVFMMIFAGLLVNLPSIASWLAWLKYLSIPRYGYSALQGNEFTGLNFCQGLNSSITPPGLAC--TGEEFLDQQGVLH-DSWGLWQNHLALGVMTLVFLAIAYLKLRFIRKF 653          

HSP 2 Score: 178.718 bits (452), Expect = 1.390e-46
Identity = 88/144 (61.11%), Postives = 107/144 (74.31%), Query Frame = 2
Query:  635 GSIISFHSISYKAK--SKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            G+ +SFH+I YK +       W K  +K IL ++NG+M PG+NAIMG TGSGKSS LD+LA RKDP  L G+VLIDG PQP NFKC+SGYVVQDD+VMGTLTVRENL FSAALRL + +   ++   V  +I+ELGL  VADSK
Sbjct:   28 GATVSFHNIHYKVRLGGGCLCWKKGPSKDILIDLNGMMKPGLNAIMGATGSGKSSFLDILAARKDPSGLSGEVLIDGAPQPPNFKCLSGYVVQDDVVMGTLTVRENLRFSAALRLPSSVKDKEKDKMVDRVIQELGLGRVADSK 171          
BLAST of ABC transporter domain-containing protein vs. Ensembl Medaka
Match: abcg1 (ATP binding cassette subfamily G member 1 [Source:NCBI gene;Acc:101161134])

HSP 1 Score: 147.132 bits (370), Expect = 2.047e-54
Identity = 115/433 (26.56%), Postives = 216/433 (49.88%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVN 2373
            +SGG+RKR  I +EL+ +P V+F DEPT+GLD+ +   V+  L+ L+R G+T++ +IHQP   +++LFD+  ++++G+ IY G+  S  + Y   LG     ++NPADF +++ +GE        DQ +   +   AV +S  E                 ++D   D K++ +++    EES                    +D          +++ S   Q   L  RT +++LR+   + +++  ++     +G++Y G+  EA     N   LFF     +    +  +  F  E  +F+ E+ + +Y + +Y+ +K + DM P +V   +V+  I Y+M     DA  FF F  + +LT+    S+   + A+ +   +A  V P+  + +++FSG+F++  +I  +LQW  Y+S  R+   G+ ++
Sbjct:  195 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSSSCFQVVSLLKALARGGRTVVCTIHQPSAKLFELFDKLYVLSQGQCIYRGRV-SRLVPYLQGLGLSCPTYHNPADFVMEVASGEYG------DQMVRLVK---AVQDSKWE---------------EHQTDADGDPKLLWQRVE---EES------------------SSSDG-------CHSFSASCLTQFSILFQRTFLSILRDSVLTHLRISSHIGIGVLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADM-PFQVAFPLVYCSIVYWMTAQPPDAARFFLFLSLGVLTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPWYLQWISYVSYVRYGFEGVILS 573          

HSP 2 Score: 87.0409 bits (214), Expect = 2.047e-54
Identity = 49/134 (36.57%), Postives = 86/134 (64.18%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQ-PKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGL 1039
            I F  +SY  +   + W K   K +LN ++G    G + AIMGP+G+GKS+++++LAG ++   ++G++LI+GQP+  ++F+ +S Y++QDD+++  LTV E +  SA L+L  ++    R   V  I++ LGL
Sbjct:   55 IEFRDVSYSIREGPW-WRKKGFKTLLNGISGKFTSGDLVAIMGPSGAGKSTLMNILAGYRETG-MKGQILINGQPRDLRSFRKVSCYIMQDDMLLPHLTVHEAMMVSANLKLQEKV--EARREMVQEILRALGL 184          
BLAST of ABC transporter domain-containing protein vs. Ensembl Medaka
Match: abcg1 (ATP binding cassette subfamily G member 1 [Source:NCBI gene;Acc:101161134])

HSP 1 Score: 113.62 bits (283), Expect = 1.494e-44
Identity = 47/121 (38.84%), Postives = 82/121 (67.77%), Query Frame = 1
Query: 1075 VSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNE 1437
            +SGG+RKR  I +EL+ +P V+F DEPT+GLD+ +   V+  L+ L+R G+T++ +IHQP   +++LFD+  ++++G+ IY G+  S  + Y   LG     ++NPADF +++ +GE  ++
Sbjct:  195 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSSSCFQVVSLLKALARGGRTVVCTIHQPSAKLFELFDKLYVLSQGQCIYRGRV-SRLVPYLQGLGLSCPTYHNPADFVMEVASGEYGDQ 314          

HSP 2 Score: 87.4261 bits (215), Expect = 1.494e-44
Identity = 49/142 (34.51%), Postives = 89/142 (62.68%), Query Frame = 2
Query:  644 ISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQ-PKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSKN 1063
            I F  +SY  +   + W K   K +LN ++G    G + AIMGP+G+GKS+++++LAG ++   ++G++LI+GQP+  ++F+ +S Y++QDD+++  LTV E +  SA L+L  ++    R   V  I++ LGL   + ++ 
Sbjct:   55 IEFRDVSYSIREGPW-WRKKGFKTLLNGISGKFTSGDLVAIMGPSGAGKSTLMNILAGYRETG-MKGQILINGQPRDLRSFRKVSCYIMQDDMLLPHLTVHEAMMVSANLKLQEKV--EARREMVQEILRALGLLDCSQTRT 192          
BLAST of ABC transporter domain-containing protein vs. Planmine SMEST
Match: SMESG000058880.1 (SMESG000058880.1)

HSP 1 Score: 915.22 bits (2364), Expect = 0.000e+0
Identity = 510/534 (95.51%), Postives = 514/534 (96.25%), Query Frame = 1
Query: 1000 IRQGDKHYQRVRIIRSCG*Q---------ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            I + D+  +   II+  G           ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK
Sbjct:  307 ITKNDRSAKVTNIIKELGLSAVADSKIGTELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK 840          

HSP 2 Score: 686.026 bits (1769), Expect = 0.000e+0
Identity = 331/332 (99.70%), Postives = 332/332 (100.00%), Query Frame = 2
Query:   65 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIQVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHI+VRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK
Sbjct:    1 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIEVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 332          
BLAST of ABC transporter domain-containing protein vs. Planmine SMEST
Match: SMESG000058880.1 (SMESG000058880.1)

HSP 1 Score: 894.804 bits (2311), Expect = 0.000e+0
Identity = 502/534 (94.01%), Postives = 507/534 (94.94%), Query Frame = 1
Query: 1000 IRQGDKHYQRVRIIRSCG*Q---------ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            I + D+  +   II+  G           ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKR       +GRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK
Sbjct:  307 ITKNDRSAKVTNIIKELGLSAVADSKIGTELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKR-------IGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK 833          

HSP 2 Score: 685.256 bits (1767), Expect = 0.000e+0
Identity = 331/332 (99.70%), Postives = 332/332 (100.00%), Query Frame = 2
Query:   65 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIQVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHI+VRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK
Sbjct:    1 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIEVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 332          
BLAST of ABC transporter domain-containing protein vs. Planmine SMEST
Match: SMESG000058880.1 (SMESG000058880.1)

HSP 1 Score: 888.641 bits (2295), Expect = 0.000e+0
Identity = 500/534 (93.63%), Postives = 505/534 (94.57%), Query Frame = 1
Query: 1000 IRQGDKHYQRVRIIRSCG*Q---------ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            I + D+  +   II+  G           ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQ+         LESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK
Sbjct:  307 ITKNDRSAKVTNIIKELGLSAVADSKIGTELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQM---------LESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK 831          

HSP 2 Score: 685.641 bits (1768), Expect = 0.000e+0
Identity = 331/332 (99.70%), Postives = 332/332 (100.00%), Query Frame = 2
Query:   65 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIQVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHI+VRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK
Sbjct:    1 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIEVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 332          
BLAST of ABC transporter domain-containing protein vs. Planmine SMEST
Match: SMESG000058880.1 (SMESG000058880.1)

HSP 1 Score: 868.226 bits (2242), Expect = 0.000e+0
Identity = 492/534 (92.13%), Postives = 498/534 (93.26%), Query Frame = 1
Query: 1000 IRQGDKHYQRVRIIRSCG*Q---------ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPXXXXXXXXXXXXXCYVQLRRVNKYK 2574
            I + D+  +   II+  G           ELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQ+         LESSGEYSEVKR       +GRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK
Sbjct:  307 ITKNDRSAKVTNIIKELGLSAVADSKIGTELLRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQM---------LESSGEYSEVKR-------IGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELILLLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNGFYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK 824          

HSP 2 Score: 686.026 bits (1769), Expect = 0.000e+0
Identity = 331/332 (99.70%), Postives = 332/332 (100.00%), Query Frame = 2
Query:   65 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIQVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 1060
            MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHI+VRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK
Sbjct:    1 MSAFSTQRDLKKHGNKYEYMEKPDQKPFDVKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFSGSYTNYAQSSQENVRKTMRPIPDDNKNNHIEVRDNRVKSDSSGVIKKHSTGRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSLYNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPGVNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVADSK 332          
BLAST of ABC transporter domain-containing protein vs. Planmine SMEST
Match: SMESG000060675.1 (SMESG000060675.1)

HSP 1 Score: 157.147 bits (396), Expect = 1.716e-52
Identity = 122/466 (26.18%), Postives = 215/466 (46.14%), Query Frame = 1
Query: 1066 LRGVSGGERKRCNIGMELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKYSIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYIDILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPKSDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPSISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYFGLKMEASVDDQN-RXXXXXXXXXXXXXXXXGAIEIFIKERPIFIHENSSGYYRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRL-DXXXXXXXXXXXXXXXXXGCXXXXXXXXXXXXXGL---ANVVCPIIYVFMMVFSGYFMNISSIFSWLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNIS----CYVTG 2436
            ++G+SGGE KR +   EL+ +P ++FLDEPT+GLD++ A +++  L++++R  KTII +IHQP   +Y +FD   +M +G  +Y G    A +N+F + G     + NPAD Y+  +                   R  AV+  S +    +               LK+++   ++K   +   +++   L +    Y++I+                Y   W NQ++ L WR  +N++R+     +++G  +F +  + +++F           N     F    L    +    +  F  + PIF  E+S+G YRV +YF S+ + D++   V P I    ++ F+ GL + D     F  LIL       CSV+     S +   +     +  PI+Y+FM+  SGY +N+ SI    ++ QY S  R+    L +N+  D       +PN++    C+  G
Sbjct:  239 VKGISGGEMKRLSFASELLINPPIMFLDEPTSGLDSYMAENILHILKKMARKNKTIICTIHQPNSEVYTMFDDILLMGEGSTVYMGSPKGA-VNFFKSCGMPCPINYNPADHYVHCI-----------------GTRDDAVVNCSVQELATRY--------------LKTEEHAKVQKSITEANCTMDNSLLEQ---TYEIISNSK-------------YKVRWCNQLRGLLWRHWINIVRDKNLFLVRVGQTVFLSIMISLIFFQQNYNDPRSQFNLNGAHFLQTTLMTYNIFYTVLNAFPSDLPIFFREHSAGMYRVDAYFISRNITDLLIFVVMPVI----LSCFVFGLVMTDHSIEKFIILILTDIAVCKCSVSLAYLLSTATVDIDFSLAITPPILYLFMLC-SGYLINLESILVPFKYIQYFSWLRYGFENLVINQWIDVHNVTCVYPNLTTKSPCFSEG 651          

HSP 2 Score: 70.0922 bits (170), Expect = 1.716e-52
Identity = 35/104 (33.65%), Postives = 66/104 (63.46%), Query Frame = 2
Query:  707 TKIILNNVNGVMLPG-VNAIMGPTGSGKSSILDVLAGRKDPKYL-EGKVLIDGQPQPKNFKCMSGYVVQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKV 1012
            T+ ++ +++G+  PG + AI+GP+G GK+++L+VL  R   + L EG+V  +GQ      K +S YV + D+ +G L V+E++ F A +++    + +DR A++
Sbjct:  113 TRQLITSLSGIAYPGRILAILGPSGCGKTTLLNVLNDRNLGELLVEGEVKTNGQALGSGIKTVSAYVQESDVFIGNLKVKEHIWFYALMKMDNHFSIDDREARI 216          
The following BLAST results are available for this feature:
BLAST of ABC transporter domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCG21.168e-13840.47ATP binding cassette subfamily G member 2 (Junior ... [more]
ABCG21.168e-13840.47ATP binding cassette subfamily G member 2 (Junior ... [more]
ABCG26.080e-12441.58ATP binding cassette subfamily G member 2 (Junior ... [more]
ABCG41.211e-4926.51ATP binding cassette subfamily G member 4 [Source:... [more]
ABCG41.211e-4926.51ATP binding cassette subfamily G member 4 [Source:... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wht-85.314e-5626.74WHiTe (Drosophila) related ABC transporter [Sourc... [more]
wht-52.004e-4624.01WHiTe (Drosophila) related ABC transporter [Sourc... [more]
wht-43.085e-4625.28WHiTe (Drosophila) related ABC transporter [Sourc... [more]
wht-64.418e-4424.94WHiTe (Drosophila) related ABC transporter [Sourc... [more]
wht-11.846e-4226.95WHiTe (Drosophila) related ABC transporter [Sourc... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
w2.536e-6529.66gene:FBgn0003996 transcript:FBtr0070490[more]
CG31642.132e-4425.88gene:FBgn0025683 transcript:FBtr0078155[more]
CG31642.132e-4425.88gene:FBgn0025683 transcript:FBtr0078153[more]
CG31642.710e-4425.88gene:FBgn0025683 transcript:FBtr0078154[more]
CG31642.710e-4425.88gene:FBgn0025683 transcript:FBtr0100379[more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcg2d2.508e-12635.36ATP-binding cassette, sub-family G (WHITE), member... [more]
abcg2d7.050e-12436.65ATP-binding cassette, sub-family G (WHITE), member... [more]
abcg2b1.151e-12340.20ATP-binding cassette, sub-family G (WHITE), member... [more]
abcg2b1.151e-12340.20ATP-binding cassette, sub-family G (WHITE), member... [more]
abcg2c1.417e-12341.95ATP-binding cassette, sub-family G (WHITE), member... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cib14.349e-13840.74calcium and integrin binding 1 [Source:Xenbase;Acc... [more]
cib15.867e-13840.74calcium and integrin binding 1 [Source:Xenbase;Acc... [more]
cib11.997e-13641.07calcium and integrin binding 1 [Source:Xenbase;Acc... [more]
cib17.878e-13639.59calcium and integrin binding 1 [Source:Xenbase;Acc... [more]
cib14.299e-13540.24calcium and integrin binding 1 [Source:Xenbase;Acc... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Abcg26.715e-13838.94ATP binding cassette subfamily G member 2 (Junior ... [more]
Abcg26.715e-13838.94ATP binding cassette subfamily G member 2 (Junior ... [more]
Abcg26.623e-12440.00ATP binding cassette subfamily G member 2 (Junior ... [more]
Abcg31.257e-9632.54ATP binding cassette subfamily G member 3 [Source:... [more]
Abcg31.192e-8831.28ATP binding cassette subfamily G member 3 [Source:... [more]
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BLAST of ABC transporter domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9UNQ0|ABCG2_HUMAN5.159e-13840.47Broad substrate specificity ATP-binding cassette t... [more]
sp|Q5MB13|ABCG2_MACMU7.019e-13840.31Broad substrate specificity ATP-binding cassette t... [more]
sp|Q4GZT4|ABCG2_BOVIN2.863e-13740.47Broad substrate specificity ATP-binding cassette t... [more]
sp|Q7TMS5|ABCG2_MOUSE6.858e-13738.75Broad substrate specificity ATP-binding cassette t... [more]
sp|Q80W57|ABCG2_RAT2.198e-13640.12Broad substrate specificity ATP-binding cassette t... [more]
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BLAST of ABC transporter domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0R8401.550e-17050.29Placenta-specific ATP-binding cassette transporter... [more]
A0A504YX085.870e-17050.29Placenta-specific ATP-binding cassette transporter... [more]
A0A4V3SGC83.728e-16948.28ABC transporter domain-containing protein OS=Opist... [more]
A0A4S2M6N04.290e-16948.28ABC transporter domain-containing protein OS=Opist... [more]
A0A267EIC84.472e-16951.35ABC transporter domain-containing protein OS=Macro... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcg2d4.867e-14040.82ATP-binding cassette sub-family G member 2 [Source... [more]
abcg2a1.382e-13742.24ATP-binding cassette sub-family G member 2-like [S... [more]
abcg2a6.566e-13540.50ATP-binding cassette sub-family G member 2-like [S... [more]
abcg2a1.225e-12840.31ATP-binding cassette sub-family G member 2-like [S... [more]
abcg2a1.449e-12739.92ATP-binding cassette sub-family G member 2-like [S... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007046.17.167e-14341.70pep scaffold:Pmarinus_7.0:GL476378:635185:650905:-... [more]
abcg2b5.080e-9840.63ATP-binding cassette, sub-family G (WHITE), member... [more]
abcb104.139e-1228.92ATP-binding cassette, sub-family B (MDR/TAP), memb... [more]
ENSPMAT00000001786.15.777e-1032.53pep scaffold:Pmarinus_7.0:GL477870:201625:214977:-... [more]
ABCB11.139e-937.29ATP binding cassette subfamily B member 1 [Source:... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
ADP11.195e-5330.37Putative ATP-dependent permease of the ABC transpo... [more]
YOL075C_mRNA4.326e-4540.77Putative ABC transporter [Source:SGD;Acc:S00000543... [more]
PDR51.073e-3739.67Plasma membrane ATP-binding cassette (ABC) transpo... [more]
PDR122.150e-3636.29Plasma membrane ATP-binding cassette (ABC) transpo... [more]
PDR103.015e-3632.70ATP-binding cassette (ABC) transporter; multidrug ... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO429681.072e-11739.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414482.197e-5428.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO439232.590e-4442.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO423626.974e-4143.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO499538.177e-3843.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ABC transporter domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcg2d5.232e-13439.46ATP-binding cassette sub-family G member 2-like [S... [more]
abcg2c2.774e-13043.48ATP-binding cassette sub-family G member 2 [Source... [more]
abcg2a1.559e-9540.93ATP-binding cassette sub-family G member 2-like [S... [more]
abcg12.047e-5426.56ATP binding cassette subfamily G member 1 [Source:... [more]
abcg11.494e-4438.84ATP binding cassette subfamily G member 1 [Source:... [more]
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BLAST of ABC transporter domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000058880.10.000e+095.51SMESG000058880.1[more]
SMESG000058880.10.000e+094.01SMESG000058880.1[more]
SMESG000058880.10.000e+093.63SMESG000058880.1[more]
SMESG000058880.10.000e+092.13SMESG000058880.1[more]
SMESG000060675.11.716e-5226.18SMESG000060675.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030306 ID=SMED30030306|Name=ABC transporter domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2992bp
CCGATCTTTATATTTCATCATTAATAAGAAATTGGCGTTGTCAAGTAAAC
ATTCGTATTTAAAAATGTCTGCTTTTAGTACGCAGAGAGATTTGAAGAAA
CACGGAAATAAATATGAATACATGGAAAAACCTGATCAAAAACCATTTGA
CGTAAAACTTACTGCTCACAAAATCGTTGAAAAGCTTCATGTGCCTATAA
ACCATTTTGTACATCAACCCCGTGATGAGCAATTAATTGATGATGATTTT
TTAAGTAGAAGTAAGTCAAATTGCGGAACAATTGAAAATGGTGGATTTTC
TGGTTCTTACACAAATTATGCTCAATCGTCTCAAGAAAATGTCAGAAAAA
CTATGAGACCAATTCCGGATGATAACAAAAATAATCACATACAAGTCAGA
GATAACCGCGTTAAATCTGATTCGTCTGGTGTTATTAAAAAGCATTCAAC
TGGACGACATAAACAAGTATCTTCATATCCAACCCAAATTTCAAATAATC
GTTCCCCTGTATTTGATAATATCGACATGAAACCTGTAAACGACAAGGAA
AATGTTTACAATAATGAATCCTTCCAAAGACGGGTGAGCGTGGACTCTCT
TTACAATGTTGATCATCGTAAAACACCGACCAAGGGTTCAATAATATCAT
TCCATAGCATCAGTTATAAAGCCAAGTCAAAAAAGTATCCTTGGAGTAAA
TCAGTGACCAAAATAATATTGAACAATGTTAATGGAGTCATGTTGCCAGG
AGTTAATGCTATCATGGGTCCAACTGGAAGTGGGAAATCCTCGATCCTCG
ACGTTTTAGCCGGAAGGAAGGATCCAAAATATCTTGAAGGGAAAGTATTG
ATTGATGGCCAACCACAACCGAAAAATTTCAAGTGCATGTCGGGTTATGT
TGTGCAGGATGACATTGTTATGGGAACATTGACTGTTAGAGAAAATCTAG
AGTTTTCAGCAGCTCTTCGGTTGTCAACGAGAATAACTAAAAATGATCGA
TCCGCCAAGGTGACAAACATTATCAAAGAGTTAGGATTATCCGCAGTTGC
GGATAGCAAGAACTTTTAAGAGGAGTTTCAGGTGGTGAACGAAAACGTTG
CAATATTGGAATGGAACTTATCACTGATCCCAGCGTTATCTTCTTGGATG
AACCTACAACCGGTTTAGATGCATTTACAGCTGCTTCTGTGATAAAAACT
TTGCAAAGACTGTCTCGAAGTGGTAAAACTATCATCCTTTCAATACATCA
ACCTAAATATTCTATCTATAAACTTTTTGATCGGTACACGATCATGGCTA
AAGGTAAAATCATCTATCATGGGAAATCTGGATCAGCACCTTTGAATTAT
TTCCATAATTTAGGATATCATATTGAACCCCATAATAATCCTGCTGACTT
CTATATAGATATTTTAAATGGAGAAGTTAAAAATGAAAAAGAAATCTTAG
ACCAACAGATTTCGTATTCAAGGCGCCATATAGCAGTGCTGGAATCTTCA
GGTGAATACAGTGAAGTGAAACGGATGCTGTTGTCCGTGAGCAAGGTTGG
ACGCCCCAAGTCAGATTTAAAAAGCGATAAAAAGGTTATCATCGAAAAGT
TGACATACGATTGGGAAGAAAGTCTCAATTTCAAAGAATTGCGGCGGCAA
TTGAATGCGTATGATGTTATAACCGAAGATGACACCGACGCGGAAATAAG
ACCGCCATCAATATCGATCACTTATGCAACATCCTGGTCCAATCAAATGA
AATGGCTTTGTTGGAGAACCGCTATGAATTTGTTGCGCAACCCACAGACA
TCGACAATTCAATTGGGAGTGTATTTATTTTTTGCATTCTCAATGGGAAT
TGTGTATTTCGGCCTGAAAATGGAGGCTTCTGTTGATGATCAGAATCGAT
TCGGTTTATTTTTCTTTGCTGCACTCCAGGTTGTTTTTGTCAATCTGGGA
GCCATTGAAATCTTCATAAAGGAAAGGCCAATATTTATACATGAAAATTC
CAGTGGATATTATCGGGTTTCCAGTTATTTTTTCTCTAAACTTCTATGTG
ACATGGTACCAATTAAAGTGTTTCCAGCTATTGTTTTCCTTCCTATTACT
TATTTCATGGCCGGTCTAAGACTTGATGCCGGTGCATTTTTCTTCTTTGA
ATTAATATTACTACTGACAACTGCTGCAGGATGTAGCGTCGCCTTTTTCG
TCAGTGCCTCGTTCAGTGTGTTCGGCTTAGCAAACGTTGTTTGTCCAATC
ATCTATGTATTCATGATGGTTTTCAGTGGATATTTCATGAATATCAGTTC
AATTTTTTCTTGGCTCCAATGGTGCCAATATTTGTCTGCGTTTAGATTTG
CACTTGGTGGTCTGTGTGTCAATGAGATGAAGGATCAATGCTATACTTTG
AAAACTTTTCCAAATATCTCATGTTATGTCACGGGAAATGTGTTTCTCGA
CCGCAATGGTTTCTATTACCTACAACCGTGGGATTTATGGAAAAATCCTC
TTGGATTATTTCTCATTTCTTTATTTTTTTTGATATTATGTTATGTGCAA
CTTCGTCGAGTGAATAAATACAAATAGACCATATCATCAAATGGAATCTT
TAACTCAGGATTCCATTTCATATCTTGCCACTCGATCTTAATGAGCACCC
TTACAATGTGGCGCTGCCTCCGTCTTACTCATTCTCATACGCATCAGGTT
TGGACCTAACAATTATAGATGACTTCTTGATCTCATCAAACAATTGCGGT
TGCAGCACTCCAGCACCAGCAGCCTTATTATTGTTATTATCATTATTATT
ATTATTACGTGATTGCTTTTGCTAATCTATCTCAATCTTTATCAAAATCC
GCTCAAATCCTTCATTTGTTATTGTTGAATTACTTCTTCATTTCAGCTTT
AATTTATTGACAATATGATTTTATTATTATTATCCCAGATTTAAATTCCC
ATATTAAATGTTATTAAATTGATTTATTTAATTGAAAAAAAA
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protein sequence of SMED30030306-orf-1

>SMED30030306-orf-1 ID=SMED30030306-orf-1|Name=SMED30030306-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=356bp
RSLYFIINKKLALSSKHSYLKMSAFSTQRDLKKHGNKYEYMEKPDQKPFD
VKLTAHKIVEKLHVPINHFVHQPRDEQLIDDDFLSRSKSNCGTIENGGFS
GSYTNYAQSSQENVRKTMRPIPDDNKNNHIQVRDNRVKSDSSGVIKKHST
GRHKQVSSYPTQISNNRSPVFDNIDMKPVNDKENVYNNESFQRRVSVDSL
YNVDHRKTPTKGSIISFHSISYKAKSKKYPWSKSVTKIILNNVNGVMLPG
VNAIMGPTGSGKSSILDVLAGRKDPKYLEGKVLIDGQPQPKNFKCMSGYV
VQDDIVMGTLTVRENLEFSAALRLSTRITKNDRSAKVTNIIKELGLSAVA
DSKNF*
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protein sequence of SMED30030306-orf-2

>SMED30030306-orf-2 ID=SMED30030306-orf-2|Name=SMED30030306-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=489bp
MELITDPSVIFLDEPTTGLDAFTAASVIKTLQRLSRSGKTIILSIHQPKY
SIYKLFDRYTIMAKGKIIYHGKSGSAPLNYFHNLGYHIEPHNNPADFYID
ILNGEVKNEKEILDQQISYSRRHIAVLESSGEYSEVKRMLLSVSKVGRPK
SDLKSDKKVIIEKLTYDWEESLNFKELRRQLNAYDVITEDDTDAEIRPPS
ISITYATSWSNQMKWLCWRTAMNLLRNPQTSTIQLGVYLFFAFSMGIVYF
GLKMEASVDDQNRFGLFFFAALQVVFVNLGAIEIFIKERPIFIHENSSGY
YRVSSYFFSKLLCDMVPIKVFPAIVFLPITYFMAGLRLDAGAFFFFELIL
LLTTAAGCSVAFFVSASFSVFGLANVVCPIIYVFMMVFSGYFMNISSIFS
WLQWCQYLSAFRFALGGLCVNEMKDQCYTLKTFPNISCYVTGNVFLDRNG
FYYLQPWDLWKNPLGLFLISLFFLILCYVQLRRVNKYK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR027417P-loop_NTPase
IPR013525ABC_2_trans
IPR003439ABC_transporter-like
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0016887ATPase activity
GO:0005524ATP binding
GO:0000166nucleotide binding
GO:0042626ATPase activity, coupled to transmembrane movement of substances
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013525ABC-2 type transporterPFAMPF01061ABC2_membranecoord: 212..422
e-value: 2.5E-35
score: 121.8
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1..82
e-value: 2.7E-17
score: 64.9
NoneNo IPR availablePANTHERPTHR19241:SF480coord: 1..487
NoneNo IPR availablePANTHERPTHR19241ATP-BINDING CASSETTE TRANSPORTERcoord: 1..487
NoneNo IPR availableTMHMMTMhelixcoord: 264..286
NoneNo IPR availableTMHMMTMhelixcoord: 230..252
NoneNo IPR availableTMHMMTMhelixcoord: 371..393
NoneNo IPR availableTMHMMTMhelixcoord: 342..364
NoneNo IPR availableTMHMMTMhelixcoord: 459..481
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 2..74