Cytochrome P450, family 1, subfamily D, polypeptide 1

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPS--------LEKNIQKSINFYCDELIRNPDNSGKGVF-PFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTD--RSDIMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            L+ PPGPW  P  G+    G N  +   RM +    +YG+++ +  G+TP+V ++      +AL  + G    GR  + T  ++S  +   F  + GP+W    R  + G+    +           LE+++ K        L      +G G F P+        N + +I  GR +    ++ + L +      +++      ++IP  RYLP   +    + + K  + + K V +  K    G  R+  D++IE+     +  +L     V L+D  I  I  D+  A ++ +     W +  L ++P++Q +I+ ++  +  + +   P+   ++ LPY++A   E FR SS V     H   +  +L G++IPKG  + VNQ+ INHD + W NP    PERFL   GA        ++ FGMG R C G +I +   FL L  L
Sbjct:   37 LKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQ----QYGDVLQIRIGSTPVVVLSGLDTIRQAL-VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTL--QELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEH----CQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSR--RPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474          

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPS--------LEKNIQKSINFYCDELIRNPDNSGKGVF-PFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTD--RSDIMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            L+ PPGPW  P  G+    G N  +   RM +    +YG+++ +  G+TP+V ++      +AL  + G    GR  + T  ++S  +   F  + GP+W    R  + G+    +           LE+++ K        L      +G G F P+        N + +I  GR +    ++ + L +      +++      ++IP  RYLP   +    + + K  + + K V +  K    G  R+  D++IE+     +  +L     V L+D  I  I  D+  A ++ +     W +  L ++P++Q +I+ ++  +  + +   P+   ++ LPY++A   E FR SS V     H   +  +L G++IPKG  + VNQ+ INHD + W NP    PERFL   GA        ++ FGMG R C G +I +   FL L  L
Sbjct:   37 LKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQ----QYGDVLQIRIGSTPVVVLSGLDTIRQAL-VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTL--QELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEH----CQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSR--RPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474          

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPS--------LEKNIQKSINFYCDELIRNPDNSGKGVF-PFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTD--RSDIMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            L+ PPGPW  P  G+    G N  +   RM +    +YG+++ +  G+TP+V ++      +AL  + G    GR  + T  ++S  +   F  + GP+W    R  + G+    +           LE+++ K        L      +G G F P+        N + +I  GR +    ++ + L +      +++      ++IP  RYLP   +    + + K  + + K V +  K    G  R+  D++IE+     +  +L     V L+D  I  I  D+  A ++ +     W +  L ++P++Q +I+ ++  +  + +   P+   ++ LPY++A   E FR SS V     H   +  +L G++IPKG  + VNQ+ INHD + W NP    PERFL   GA        ++ FGMG R C G +I +   FL L  L
Sbjct:   37 LKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQ----QYGDVLQIRIGSTPVVVLSGLDTIRQAL-VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTL--QELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEH----CQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSR--RPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474          

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNS----------GKGVF-PFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVT------EKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR---SDIMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            L+ PP PW  P  G+    G N  +   RM +    +YG+++ +  G+TP++ ++      +AL  + G    GR  + T  ++++ +   F  + GP+W    R  +  ++    T S+  +   S + Y +E +     +          G G F P+++      N + ++  G+ F    ++ + L  +  +  +       +++ P  RYLP   ++R    + +    L K V +  +    +N+  +I   L + ++     +      EK VNL +        DI  A ++ +     W +  L   P+IQ +I+ ++  +  +++   P+   + +LPY++A   E FR SS +     H   +  TL G++IPK C + VNQ+ +NHD E WE+P   +PERFL + G   ++     +M FGMG R C G  + K   FL L  L
Sbjct:   39 LKSPPEPWGWPLLGHVLTLGKNPHLALSRMSQ----RYGDVLQIRIGSTPVLVLSRLDTIRQAL-VRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALN----TFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQ-DFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVN--------DIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRER--RPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAIL 475          

Query:  108 LPPGPWALPFWGNY---------------------RGFNGAMIYKR-MVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTP-SLEKNIQKSINFYCDELIRNPDNSGKGVF-PFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSE--FVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIE-YLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNY 1418
            +PPGP   P  GN+                      G + ++I  + ++ +    YG++ + F G+  +V ++D+    EAL  +  +  + R  V    IV++E+  +F + YGP+W++  +     +   GL   SLE  I +   +   E+ ++    G+  F PF        N + S+  G+ F   + ++  +     +  +I   S+   VN  P+  YLP    + L +    + + L K + D ++    R NP + I+ YLL   E  K       + ++ ++  I  D+  A  +    + +W +  + L+P +QE++  +I ++    +   P    K ++PY +A   E  R + +V +   H   ++  L GY IPKG LI  N ++++ D   WE PE   P RFLD  G    +   +PFG+G R+C G  + K   FL+  +L  ++
Sbjct:   59 IPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREAL-VQQAEVFSDRPRVPLISIVTKEKGVVFAH-YGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKH----GEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQE-SLDRENPQDFIDMYLLHMEEERK--NNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANR--APSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511          

Query:   57 VGLLSVFVILKFIERLRLPPGPWALPFWGNYRGFNGAMIYK-----RMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSL-EKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLS-IVIGRTFTLEDEDYIILQDSRRQVFDI-MDKSEFVNWIPFGRYLPLKCIRRL----FEQSTKLNNLLAKFVS-DARKMGR------YRNNPDNIIE----YLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSE 1439
            V ++S     +F++  RLPPGP++LP  GN     G  +++      M+ +++ +YG++ TL+ G  P V I +Y+L+ E    KN    A +      D V +     F N  G  W+E+ R   L +   G+   L E+ I   ++  C E I      G  V   +E + L+  ++++ +++G  F    +   +   + + +FD  MDK       P    LP+  +++     F    K    +  +VS DA K  R      Y  +P+N+ +    +LL+  +N K     + NL     + +  D+     E    T +        +PQ+ + ++ ++ K+ +           K E PY+ A   E  R +SI+ I  +    +   +GG+ +  GCLIA    A++ + + +ENPE   PERF+ +          +PFG+G R C G S+ +   +L++ NL L Y  + S +
Sbjct:    8 VSIISFLTARQFLKAKRLPPGPFSLPLIGNAHQV-GYQLWRTGGVTNMLNHFRKEYGDIFTLWLGPIPHVNITNYELSHEVFV-KNSTKYADKHVSPMIDYVRKGNGVFFSN--GDKWQELRRFSMLTMRNMGMGRDLMEEKILSELDARCAE-INEKSIDGTTVLQVNEFFDLTVGSIINNMLLGFRFDERTKSRFL---TMKHMFDEGMDK-----MTPLFFTLPVWALQKFLAKDFNSIIKDQFEIIDYVSVDAIKRSRDFMNGDYEIDPNNVEDIVDAFLLKMKQNPKSDVYDENNL-----KMLITDLWITGQETTTTTLVSAFIQFLNNPQVMDTVQKELIKVTNGGSRQL-SLRDKTETPYLNATIAEVQRHASILNINFWRINNEPTVIGGHPVDSGCLIASQLSALHTNEKIFENPEKFNPERFIRNENLM---QQTIPFGIGKRSCLGESLARAELYLIIGNLLLRYNFESSGK 469          

Query:   63 LLSVFVILKFIERLRLPPGPWALPFWGN------YRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPS-LEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVL-SIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFE---------QSTKLNNLLAKFVS--DARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHI---RQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELV 1460
            LL   ++ ++ +  RLPPGP +LP  GN      Y    G ++    ++ ++ +YGN+ TL+ G  P V I DY+ + E      GK+     +    D+ ++    +   N G  W+EM R         G+    +E  I + ++  C ++ +   N G  +    E + L+  +++ SI++G+ F  ED  +  L+     + + MD S F  + PF    P+  ++  F+         Q T  N   A+ +   ++ K G+Y  + +N+ +Y    T+   L  +K+    D +I   + +  D+     E    T I     L LHP++  + R +I K+           + +   PY+ AV  E  R +SI+ +  +    +   +GG+ +  G L+     A++ +   ++NP+   PERF+           ++PFG+G R C G S+ K   +L+  NL L YK +   +   TEL+
Sbjct:   10 LLGYLIVRQYQKVSRLPPGPISLPLIGNLPQIIYYLWSTGGIV--STLDLFRKRYGNIFTLWVGPIPHVSIADYETSHEVFVKNAGKYADKFHAPVMRDVRND--IGVLITN-GDHWQEMRRFSLQAFRNMGVGKDIMETRIMEELDARCSDIDKLATN-GVTITHASEFFDLTVGSIINSILVGKRFE-EDTKHEFLK-----IKETMDAS-FETFSPFDMTAPVWFLKTFFKHRYDKIWSAQETAKNFAAAEAIKRVESIKSGKYVIDENNLQDY----TDAFLLKIQKEGESKDFNIETLKTMIIDLWMTGQETTTTTLISGFNQLLLHPEVMIKAREEILKITENGSRHLSLTD-RTSTPYVNAVIGEIQRHASILNVSFWKINKEFTYMGGHPVDAGALVTSQLSALHVNETVFKNPQEFNPERFIRDGKLL---QKVIPFGVGKRNCLGESLAKAELYLIFGNLLLRYKFEQHGKLSTTELM 476          

Query:   63 LLSVFVILKFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMV----EYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSL-EKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVL-SIVIGRTFTLED-EDYIILQDSRRQVFDIMDKSEFVNWIPFGR-YLPLKCIR--RLFEQSTKLNNLLAKFVSDARKMGRYRNN---PDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTP-KFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTE 1454
             L+V +I ++ +  +LPPGP +LP  GN       +  ++ V    + ++ KYG++ T++ G  P V I +Y+ + E    KNG     R        VS     +F  N GP+  EM +   L     G+   L E+ I   +N  C E+  +  N GK +    E + L+  +V+ S+++G+ F  ED +D++ ++    +  D+    + V  + F + + P +  R   +FE++    +  A    +  K G Y  N   P + +E  L + E  +L  +         ++ +  D+  A  +    T +     L  +P+I  + R +I ++   +  S P + + + E  Y+ A   E  R +SI+ +  +    +  T+ G+ +  G +I     A++ + + ++NP+   PERF+++       S I+PFG+G R C G +I K   +L++ NL L Y IK       TE
Sbjct:   10 FLAVLIIRQYQKARKLPPGPVSLPLIGNIHQLVYHIWNEKGVVPAFDLFRKKYGDVFTIWLGPIPHVSICNYETSQEVFV-KNGNKYKDRFLPPVYLHVSNNL-GLFTAN-GPVCAEMRKFTLLAFRNMGVGRDLMEQRILDELNTRCAEIDADAVN-GKTIVHTTEFFDLTVGSVINSLLVGKRFEAEDKDDFLEIKRLMAEAADLFTMFDLVVPVWFLKSFFPSRFERVVAIFEKALNYLSREALARYEKLKTGEYSVNAEDPQDFVEAYLAKMEQERL-RDSDTPYTMECLKFVIGDLWLAGQDTTSTTLVAGFNHLVKNPEIVRKCREEILRIT--ENGSRPLQLKDRAESHYLNATIAEIQRHASILNVNFWRLVHEPTTVQGHPVDSGSVICAQLGALHVNDDLFKNPDKFYPERFIENEQLL---SQIIPFGIGKRSCVGENIAKSELYLMIGNLILRYDIKPHGSEPSTE 477          

Query:  105 RLPPGPWALPFWGNYRGF--NGAMIYKRMVEY--YKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSL-EKNIQKSINFYCDELIRNPDNSGK-----GVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDS---RRQVFDIMD--------KSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRY---RNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIK 1427
            RLP GP  LP  GN+  F   G  +   +  Y  ++  YG + T++ G  P V+I+DY +A E+   K     + R +  T + + E R  I  N  G  W++  R     +   GL  +L E+ I +  N+   +  R    +G      G F FD    L  + +  ++I   F   D+++  ++ S     + F I+D         S  + W     + P   I   +E S +  NL  +   +A K G +       D +  Y+L+  ++         NL +  I  +F D+  A  E    T  W    L  HP + +++R ++ KL    +        + + PY+ AV  E  R +SI+ I  F    +   + G  +  GC++      ++ D E ++NP   +PERFL+++   T    ++PFG+G R CPG S+ +   +L+L N+ L+ +I+
Sbjct:   24 RLPKGPTPLPLIGNFHQFIYYGIKLGSAVAVYHEFEKTYGKVFTIWMGPLPSVYISDYDVAHES-HIKRANIFSTRFAHGTTNYIREGRGIIAAN--GDFWQDHRRFALTTLRNFGLGRNLMEEKIMEEYNYRISDYKRTHLKNGAIEIHAGTF-FD---LLVGSIINQLLISERFEQGDQEFEKIKTSLALSLENFGIIDIFFPTAILDSPLMKWRQKKIFEPFDFI---YEVSKR--NLTKRM--EAVKSGDHVIEDGGRDFVDAYILKIQKDENSGAPSTFNL-ETMIIDVF-DLWQAGQETTSTTLTWAFCCLLNHPNVVKKLRAELMKLTGGNRHV--GLNDRADTPYLNAVCNEVQRIASILNINLFRKIEQDTEIAGQPLASGCVVTTQMSMLHTDVEVYKNPTEFRPERFLENN---TLEKKLIPFGIGKRSCPGESLARAELYLILSNVILDVEIE 467          

Query:  105 RLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYG--PLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPF-DESYWLSDNTVLSIVIGRTFTLEDEDYII-LQDSRRQVFDIMDKSEF-VNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYL-LQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYK 1421
            R PPGP  +  +GN    N     +  +EY +  YG + TL     P + + +YK   EAL  KNG+  +GR S ++  + + +R N  G        WK+M   +   ++K    P  E  +  +    C E         K +    D       N +  I IGR +  +D+++   L+D    V +IM    F VN  P+ RYLP   +R+          L   F +   +    R+  D +   + LQE+        K+    D+ I     D+     E    T  W +  L  +P++Q + +++I  +     +  P     N+ PY++A   E  R ++++     H  ++   +GGY IP    I     A+  D   +E+P+  KPERFLD  G +    +  PFG+G R+C G  I +   +L+  +L  N++
Sbjct:   91 RYPPGPPPMAVFGNSPFVNILTPEQTFLEY-REIYGPIFTLHLSQ-PTIILAEYKTIQEAL-VKNGQQTSGRSSAESFVLFTGDRLNGDGVILAMRQKWKDMRHEISRFMNKWYGAPMDELVLHHT---RCLEQELAKIAETKSLIDLRDPLAGAIANVIQQITIGRNYMYQDQEFQTQLRDINAVVKEIMTAEVFFVNCYPWLRYLPEGILRKWTNYKRSGFRLQQWFRTILEEHHVNRHQGDFMSHMIDLQES--------KQEQFRDLSIILTCGDMWTGGMETTVTTLRWGIIYLLNNPEVQAKCQMEILDVFG---NDIPDMGKMNQTPYVRATLSEIQRLANVLPWAIPHKTIEECNIGGYDIPVNTEIIPALGAVLFDPNVFESPKQFKPERFLDEEGKYRVMEEFRPFGLGPRVCLGERIARTELYLIFASLLQNFR 518          

Query:    6 FYLFGLKMWQDILTGAGVGLLSVF------------VILKFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFG--NNYGPLWKEMIRALKLGVSKCGLT--PSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLP-LKCIRRLFEQSTKLNNLLAKF------VSDARKMGRYRNNPDNIIEYLLQETENSKLV-TEKKVNLNDVH---IRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKI 1424
            F L  L++ QD   G    LL VF            ++  + E  +LPPGPW LP  G Y  F G+  + R +E  K +YG+L +   G+   V ++DYK+  E    +      GR      D    +  N +G  N+ G LWK+  R L   + + G+T   + ++ +QK I     E I +   S     P D S  +S    N + S+++   F+++D  +      RR  F I +       I    Y+P ++C   +     K+    A+       V D  K     NN  +++++ L E E +K   T+ ++     H   + Q+  D+  A  E I  T +W    +  +P+   R++ ++ ++  + +   P  E    LP  ++   E  R SSIV +   H   + V L GY IP G  +     +++ D   WE PE  +P RF+D+ G        +PFG+G RMC G  + +   FL   +    + I
Sbjct:   10 FVLRQLQVQQD---GDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIG-YLLFMGSEKHTRFMELAK-QYGSLFSTRLGSQLTVVMSDYKMIRECFRREE---FTGRP-----DTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQ--PVDMSPVISVAVSNVICSLMMSTRFSIDDPKF------RRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHR--LPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDI 489          

Query:    6 FYLFGLKMWQDILTGAGVGLLSVF------------VILKFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFG--NNYGPLWKEMIRALKLGVSKCGLT--PSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLP-LKCIRRLFEQSTKLNNLLAKF------VSDARKMGRYRNNPDNIIEYLLQETENSKLV-TEKKVNLNDVH---IRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKI 1424
            F L  L++ QD   G    LL VF            ++  + E  +LPPGPW LP  G Y  F G+  + R +E  K +YG+L +   G+   V ++DYK+  E    +      GR      D    +  N +G  N+ G LWK+  R L   + + G+T   + ++ +QK I     E I +   S     P D S  +S    N + S+++   F+++D  +      RR  F I +       I    Y+P ++C   +     K+    A+       V D  K     NN  +++++ L E E +K   T+ ++     H   + Q+  D+  A  E I  T +W    +  +P+   R++ ++ ++  + +   P  E    LP  ++   E  R SSIV +   H   + V L GY IP G  +     +++ D   WE PE  +P RF+D+ G        +PFG+G RMC G  + +   FL   +    + I
Sbjct:   10 FVLRQLQVQQD---GDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIG-YLLFMGSEKHTRFMELAK-QYGSLFSTRLGSQLTVVMSDYKMIRECFRREE---FTGRP-----DTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQ--PVDMSPVISVAVSNVICSLMMSTRFSIDDPKF------RRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHR--LPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDI 489          

Query:   72 VFVILKFIERL------RLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGN-----NYGPLWKEMIRALKLGVSKCGLT---PSLEKNIQKSINFYCDELIRNPDNSGKG-----VFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLP--LKCIRRLFEQSTKLNNLLAKFV-----------------SDARKMGRYRN--------------------------------NPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV 1526
            V VIL   ER         PPGPW LPF G Y  F  A    + ++    +YG +  L  G  P V ++D  L  +            R+ V T        H I G          +W+   R     +   G+T     L   +++ I    DE +R  D   K      V P    +    N +  +V G T+  +D D++ LQ  + +   ++  S  VN++P+ R+LP  ++ IR L E   K + +  + V                  + +++ R                                    P+ I+E+ L   +     T+ ++  +D  +R +  D+  A  +    T  W++  L    + Q R+   +  L       +P  E    L Y++A   E  R  S+V +   H   ++  +G Y I  G +I  +++AI+ D   +  PE  +PERFL + GA+      +PF  G RMCPG  + +    L    +   + ++  S  E    VD    + +   P  ++L  +K+
Sbjct:   30 VLVILYLCERQCNDLMGAPPPGPWGLPFLG-YLPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFF----------RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRD-----TDSQLYCDD-QLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELLLPL-----GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTE----VDMAGESGITLTPTPHMLRFTKL 558          

Query:   72 VFVILKFIERL------RLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGN-----NYGPLWKEMIRALKLGVSKCGLT---PSLEKNIQKSINFYCDELIRNPDNSGKG-----VFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLP--LKCIRRLFEQSTKLNNLLAKFV-----------------SDARKMGRYRN--------------------------------NPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV 1526
            V VIL   ER         PPGPW LPF G Y  F  A    + ++    +YG +  L  G  P V ++D  L  +            R+ V T        H I G          +W+   R     +   G+T     L   +++ I    DE +R  D   K      V P    +    N +  +V G T+  +D D++ LQ  + +   ++  S  VN++P+ R+LP  ++ IR L E   K + +  + V                  + +++ R                                    P+ I+E+ L   +     T+ ++  +D  +R +  D+  A  +    T  W++  L    + Q R+   +  L       +P  E    L Y++A   E  R  S+V +   H   ++  +G Y I  G +I  +++AI+ D   +  PE  +PERFL + GA+      +PF  G RMCPG  + +    L    +   + ++  S  E    VD    + +   P  ++L  +K+
Sbjct:   30 VLVILYLCERQCNDLMGAPPPGPWGLPFLG-YLPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFF----------RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRD-----TDSQLYCDD-QLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELLLPL-----GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTE----VDMAGESGITLTPTPHMLRFTKL 558          

Query:  108 LPPGPWALPFWGNYRGF---NGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLT---PSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDN-TVLSIVIGRTFTLEDEDYIILQD--SRRQVFDIM--------------DKSEFVNWIPFGRYL--PLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDI-MPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNIS 1520
             PPGP  +P +G+Y      N   ++K  +   +    +++ L  G  P+  ++      E L N+              D   + R   F +  GPLWKE  R +   +   G       LE  IQ+ +N   D LIRN        +P +     S    VL  ++   F+     YI+  +  SR ++  ++              D  + ++ IP+ R++        +L E +  +    A FV       +Y ++ +  +E    +   +++        N   +     D  F ++  IG+     +  L L+P +  R++ +I ++    +   P  E +  LP+ +A   E  R  ++V     H AL+   L GY IPK  ++  + YA + DA  W +PE  +PERFLD+ G    + D+ +PFG G R+C G +  +   FL+   +C ++       +   +L  +    ++   P D+ L + 
Sbjct:   29 FPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQD--GPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLD-LIRNGPK-----YPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVD------KYLDSYEEGVERNFMDVYIAEMRRGPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGR--LPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLII--SPPDFWLQLQ 507          

Query:   57 VGLLSVFVILKFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDK--SEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSE 1439
            + +L VF++++       PPGP  LP +GN   FN A   K   E +  KYGN+ +L+ G+ P VF+N + +  EAL NK  +  +GR        ++E +  +  + YGPLWK+  R   + +   GL   S+E+ I   I+     L +N    GK V P    + ++ N +  ++ GR F    E          ++  I++   +   + +PF R LPL   ++ F+    L  +  K + D  K  R    P + I+  L E +  K    +    ++  +     D+ FA  +    T +     L  HP++Q + + +I  +   K   +  +E ++ +PY  AV +E  R ++ V +  FHC  +   L GY IPKG LI  N   +  +  +W+ P    P  FL+  G F      +PF  G R+C G  + +   FL+   L   YK  W  +
Sbjct:   10 ICILLVFLLIRIQRPKNFPPGPSPLPIFGNLLHFNLANPLKDF-ERFAEKYGNIFSLYTGSRPAVFLNSFAVIKEALVNK-AQDFSGRPQDFMISHLTECKGVVLAD-YGPLWKDHRRFALMTLRNFGLGKQSMEERILGEISHVVCYLDKN---IGKTVDPQVMFHNVASNVISLVLFGRRFDYNSETLQCYIQLITEISKILNGPWNMIYDTLPFLRILPLP-FKKGFDHVKVLKGMNLKLI-DEHKSTRVPGKPRDFIDCYLDELDKRK---NEVSTFSEDQLLMYILDLYFAGTDTTSNTLLTAFLYLMNHPEVQVKCQQEIDDVLEGKDQVS--YEDRDNMPYTLAVIHEVQRVANTVPLSVFHCTTRDTELMGYSIPKGTLIIPNLTIVLKEEGQWKFPHEFNPANFLNEQGQFEKPEAFIPFSTGPRVCLGEGLARMELFLVFVTLLRRYKFVWPRD 460          

Query:   57 VGLLSVFVILKFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDK--SEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSE 1439
            + +L VF++++       PPGP  LP +GN   FN A   K   E +  KYGN+ +L+ G+ P VF+N + +  EAL  K  +  +GR        ++E +  +  + YGPLWK+  R   + +   GL   S+E+ I   I+     L +N    GK V P    + ++ N +  ++ GR F    E          ++  I++   +   + +PF R LPL   ++ F+    L  +  K + D  K  R    P + I+  L E +  K    +    ++  +     D+ FA  +    T +     L  HP++Q + + +I  +   K   +  +E ++ +PY  AV +E  R ++ V +  FHC  +   L GY IPKG LI  N   +  +  +W+ P    P  FL+  G F      +PF  G R+C G  + +   FL+   L   YK  W  +
Sbjct:   10 ICILLVFLLIRIQRPKNFPPGPSPLPIFGNLLHFNLANPLKEF-ERFAEKYGNIFSLYTGSRPAVFLNSFAVIKEALVTK-AQDFSGRPQDFMISHLTECKGVVLAD-YGPLWKDHRRFALMTLRNFGLGKQSMEERILGEISHVVGYLDKN---IGKTVDPQVMFHNVASNVISLVLFGRRFDYNSETLQCYIQLITEISKILNGPWNMIYDTLPFLRILPLP-FKKGFDHVKVLKGMNLKLI-DEHKSTRVPGKPRDFIDCYLDELDKRK---NEVSTFSEDQLLMYILDLYFAGTDTTSNTLLTAFLYLMNHPEVQVKCQQEIDDVLEGKDQVS--YEDRDNMPYTLAVIHEVQRVANTVPLSVFHCTTRDTELMGYSIPKGTLIIPNLTIVLKEEGQWKFPHEFNPANFLNEQGQFEKPEAFIPFSTGPRVCLGEGLARMELFLVFVTLLRRYKFVWPRD 460          

Query:  204 KYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTEL 1457
            +YG L  L+ G    + +++  L  E L  + G+  AGR  + T D++++   +I   +Y PLWK   R +    +  G  +  L+  +Q++ +  C+EL      S       D S  L     N +  +V   ++   D +   +      +   + +   V+  P+ R  P K ++RL E  +  + LL K + + +K       P ++++ LL   +      +   ++ + H+     +   A  E    T +W +A L  HPQ+QER++ ++ +      D  P    +  LP + AV  E  R   +  IL  H A++  +LGG+ +PKG  + VN +AI+HD + W+ PE   PERFL+ SG    +S  +PFG G R+C G S+ +   FL +  L   +     SE    +L
Sbjct:   66 QYGPLFGLYAGPHLTLVVSEIGLVREVLLQR-GREFAGRPKMVTTDLLTQGGKDIAFADYSPLWKNHRRLVHSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSS------DLSVVLMRAVTNVICRLVFSSSYQPSDPELQTVIQYNDGIVQTIARGGLVDIFPWLRIFPNKDLKRLKECVSIRDQLLYKKLLEHKK-SLTPGEPRDLLDALLIGQQRGSGGAD---DITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQLQERVQAELDECVGV--DRPPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQPEQFNPERFLEPSGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVSRLLQRFSFSCPSEASLPDL 474          

Query:   63 LLSVFVILKFIERLR-LPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLE--KNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKF----VSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTD--RSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSS 1436
            LLS+ V L  + R R L PGP++ P  GN    G      + RM +    KYG++  +  G+  +V +N    AI+    K     AGR    +   VS  +   FGN Y P WK + R +     +   T +++  +  +K I     ELIR   N  +    F    +L     NT+ ++  G  +  +D ++  +     Q    +     V+ +P+ +Y P   IR LF+Q  +LN     F    VS+ RK       R+  D  I  L     +  L     V+L+   +     DI  AS + +     W + LL  +P+IQ+R++ D+ ++  + +   P    +  LPY+ A  YE  RF+S   +   H   K  ++ GY IPK  +I VNQ+++NHD  +W+ PE   P+RFLD  G+      ++++ F +G R C G  ++K   FL    L      K  S
Sbjct:   20 LLSLMVCLMLMFRRRQLVPGPFSWPVIGNAAQLGNTPHFYFSRMAQ----KYGDVFQIKLGSRNVVVLNGD--AIKEALVKKATDFAGRPDFASFRFVSNGKSMAFGN-YTPWWK-LHRKVAQSTVRNFSTANIQTKQTFEKHIVSEIGELIRLFLNKSREQQFFQPHRYLVVSVANTMSAVCFGNRYAYDDAEFQQVVGRNDQFTKTVGAGSMVDVMPWMQYFP-NPIRTLFDQFKELNKEFCAFIELKVSEHRKTISPSHVRDMTDAFIVAL-----DKGLSGGSGVSLDKEFVPPTISDIFGASQDTLSTALQWIILLLVRYPEIQKRLQEDVDRVVDRSR--LPTIADQPHLPYLMAFIYEVMRFTSFTPLTIPHSTTKDTSINGYPIPKDTVIFVNQWSLNHDPTKWDQPEVFNPQRFLDEDGSLNKDLTTNVLIFSLGKRRCIGEDVSKIQLFLFTSVLVHQCSFKAES 478          

Query:   63 LLSVFVILKFIERLR-LPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLE--KNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKF----VSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTD--RSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSS 1436
            LLS+ V L  + R R L PGP++ P  GN    G      + RM +    KYG++  +  G+  +V +N    AI+    K     AGR    +   VS  +   FGN Y P WK + R +     +   T +++  +  +K I     ELIR   N  +    F    +L     NT+ ++  G  +  +D ++  +     Q    +     V+ +P+ +Y P   IR LF+Q  +LN     F    VS+ RK       R+  D  I  L     +  L     V+L+   +     DI  AS + +     W + LL  +P+IQ+R++ D+ ++  + +   P    +  LPY+ A  YE  RF+S   +   H   K  ++ GY IPK  +I VNQ+++NHD  +W+ PE   P+RFLD  G+      ++++ F +G R C G  ++K   FL    L      K  S
Sbjct:   20 LLSLMVCLMLMFRRRQLVPGPFSWPVIGNAAQLGNTPHFYFSRMAQ----KYGDVFQIKLGSRNVVVLNGD--AIKEALVKKATDFAGRPDFASFRFVSNGKSMAFGN-YTPWWK-LHRKVAQSTVRNFSTANIQTKQTFEKHIVSEIGELIRLFLNKSREQQFFQPHRYLVVSVANTMSAVCFGNRYAYDDAEFQQVVGRNDQFTKTVGAGSMVDVMPWMQYFP-NPIRTLFDQFKELNKEFCAFIELKVSEHRKTISPSHVRDMTDAFIVAL-----DKGLSGGSGVSLDKEFVPPTISDIFGASQDTLSTALQWIILLLVRYPEIQKRLQEDVDRVVDRSR--LPTIADQPHLPYLMAFIYEVMRFTSFTPLTIPHSTTKDTSINGYPIPKDTVIFVNQWSLNHDPTKWDQPEVFNPQRFLDEDGSLNKDLTTNVLIFSLGKRRCIGEDVSKIQLFLFTSVLVHQCSFKAES 478          

Query:   36 DILTGAGVGLL--SVFVILKFIERLR------LPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTP-SLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDK--SEFVNWIPFGRYLPLKCIRRL---FEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFK---DILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLL 1511
            +IL    V L+  + F++L  I+ +R      LPPGP  LPF GN+    G  ++K ++E+ K KYG + T+  G  P+V +  + +  EAL N NG     R  +   + +S   H +  +N G  WK++ R   + +   G+   S+E+ IQ+  +F  +E         KG  P D +++ S    N + S+V G  F  ED +++ L     QVF        +  N  P       K + +L        K  N L +F+     M +   +P +  +++  +    K+  EK V   + H++       D+  A  E +  T  + + +L  HP I+ERI+ +I  +  + +   P  E ++ +PY  AV +E  RF  I+ +   H   + +   GY IPKG  +     ++ HD ++++ P+   P  F+D +G F      MPF  G R+C G  + +   FL +  +  NY ++   + E  +L   PE +     P+ Y L
Sbjct:    2 EILGATAVLLVICAFFLLLNTIQVIRRQGKGKLPPGPTPLPFLGNFLQLRGEEVFKSLLEFGK-KYGPVYTIHLGMEPVVVLCSFDIVKEAL-NDNGDEFGARGHMPLLEKISHGGHGVVASN-GERWKQLRRFSLMTLRNFGMGKRSIEERIQEEAHFLTNEF-----KYTKGQ-PVDPTFYFSKAVSNVICSVVFGDRFEYEDTEFLRLLGLLNQVFRGFSSVWGQLYNIFP-------KVMGKLPGPHNMIFKSVNSLQEFIMQRINMHQETLDPSSPRDFI--DCFLIKMQQEKDVPQTEFHMQGALNTTFDMFGAGTETVSTTLRYGLLILLKHPDIEERIQKEIDSVIGRNR--APCIEDRSRMPYTDAVIHEIQRFVDIIPMGIPHKVTRDIQFQGYFIPKGTTVYPMLSSVLHDPKQFKYPDIFNPGHFIDENGKFCKNDGFMPFSSGKRICVGEGLARMELFLFITTILQNYTLRSPVDTEDLDLT--PELSGFGNIPRPYKL 491          

Query:   51 AGVGLLSVFVILKFIERLRLPPG------PWALPFWGNYRGF--NGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDN--SGKGVF-PFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            A +    VF++++  +R++LPPG      P   P  GN      N  +   +M E     YG++  +  G  P++ ++  +   +AL  +     AGR  + T  +V + +   F ++ G +W+   R    ALK   +    T S    ++++I    + LIR        KG F P+        N +  +  G+ +  +DE+ + + +   +           ++IP  +YLP   ++   E + K    + KF  +  K    +N+  +I + L+Q ++  ++     + L++  I  I  D+  A ++ I     W +  L  HP IQ+RI+ ++ ++  +++   P+   + +LPY +A   E FR SS +     HC  K   L GY IPKG  + +NQ+ +NHD   W++P    PERFL++ G   ++++   +M FG+G R C G +I +   FL L  +
Sbjct:   23 ASIVFAIVFLVIR-SQRVKLPPGTKKLPGPMPYPVIGNLLSLSKNPHLSLTKMSE----TYGDVFQIQIGTKPMLVLSGLETLRQALI-RQSDEFAGRPDLFTFRLVGDGQSMTFSSDSGEVWRARRRLAQNALKTFATSPSPTSSNSCLVEENIITEAEYLIRKFKELIDDKGEFDPYRYVVVSVANVICGMCFGKRYNHDDEELLNVVNLTDEFGAAAASGNPADFIPILQYLPNSSMKAFKEINQKFLAFMQKFTKEHYKTFD-KNHIRDITDSLIQHSQEKRVDENSNIQLSNEKIVNIVNDLFGAGFDTITTALSWSLMYLVAHPNIQQRIQDELDQVIGRER--RPRLSDRAQLPYTEAFILEMFRHSSFMPFTIPHCTTKDTMLNGYFIPKGICVLINQWQVNHDPNLWQDPFKFCPERFLNNDGTMVNKTEMEKVMIFGLGKRRCVGEAIGRMEVFLFLTTM 483          

Query:   87 KFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR-----ALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSD---NTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKS--EFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDIL---FASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLN 1514
            K   +  LPPGP  +P +GN        + K ++E  K KYG++ TL++G +P+V +  Y+   EAL ++  +  +GR ++ + D   +    +F N  G  WK + R         G+ K G+    E+ I++   F   E+    +       PFD +  L     N + S+V G  F   ++D+  L    + VF     S  + +N +P          + +     KL + + + V +  K     N+P ++I+  L      K+  E K   +  H++ +   IL   FA  E +  T      +L +HP+I+ +++ +I ++  + +  +P  E +N++PY  AV +E  R S ++ +   H   K     GY IPKG  I     A+  D E+++ P    P  FLD  G F      MPF  G R+C G  + +   FL L N+  N+K+   SE+  TE    P+      +P  Y L+
Sbjct:   26 KMYRKRNLPPGPTPIPLFGNVMQIKRGEMVKSLIELGK-KYGDIYTLYFGPSPVVILCSYRAIKEALIDQ-AEEFSGRGAIPSFDQYFQGYGVVFTN--GEEWKNLRRFSLSTLRNFGMGKRGI----EERIKEEAQFLVAEIKSYKEK------PFDPTNILVQCVSNVICSVVFGNRFEYANKDFQNLLSLFQSVFQETSSSWGQLLNMLPAVMNHVPGPHKNIIRDMNKLEDFVLQRVKENEKTVD-PNSPRDLIDSFL-----IKMQQENKNPTSPFHMKNLIATILSIFFAGTETVSTTLRHGFLILLIHPEIEAKLQEEIDRVVGQNR--SPTIEDRNKMPYTDAVIHEIQRLSDVIPMNVPHLVTKDTKFRGYTIPKGTNIYPLLCAVLRDPEQFDTPSKFNPNHFLDDKGCFKSNDGFMPFSTGKRICLGEGLARMELFLFLTNILQNFKLH--SESGLTEDNIAPKMKGFANYPTSYQLS 490          

Query:   87 KFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTP-SLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSD---NTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKS--EFVNWIP-FGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDIL---FASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDY 1505
            K   +  LPPGP  +P +GN        + K ++E  K KYG + TL++G +P++ + DY+   EAL N   +  +GR  + + D   +     F N  G  WK++ R     +   G+    +E+ IQ+   F   E+      S KG  PFD +  L     N + S+V G+ +   ++D+  L    + VF+    +  + +  +P    ++P    + +  +  K+N+ + + V +  K     N+P + I+  L + +      EK   +   H + +   I+   FA  E +  T      +L +HP+I+E++  +I ++  +  D +P  E ++++PY  AV +E  RFS ++ +   H  +K     GY IPKG  +     A   D +++  P    P+ FLD +G F   +  +PF  G R+C G  + +   FL L N+  N+K+   SEN+F E    P+      +P  Y
Sbjct:   26 KMYRKRNLPPGPTPIPLFGNVLQIKRGEMVKSLLELGK-KYGPVYTLYFGPSPVIILCDYQSIKEAL-NDQAEEFSGRGKIPSWDQFFQGYGESFSN--GDEWKQLRRFSLTTLRNFGMGKRGIEERIQEEAQFLVAEI-----KSYKGK-PFDPTKILVQCVSNVICSVVFGQRYEYSNKDFHKLLYMFQAVFEDTSSTLGQLMTLLPNIMNHIP-GPHKTVVNKLNKVNDFILQRVKENEKTLD-PNSPRHFIDSFLIQMQK-----EKDNPVTKFHWKNLLCTIMNLFFAGTETVSTTLRHGFLMLLIHPEIEEKLHEEIDRVVGQ--DRSPTIEDRSKMPYTDAVIHEIQRFSDVLPMSLPHLVMKDTQFRGYTIPKGTDVYPLICAALRDPKQFATPNKFNPQHFLDDNGLFKSSNAFLPFSTGKRICLGEGLARMELFLFLTNILQNFKLH--SENQFAEDDIAPKMNGFANYPLSY 487          

Query:   39 ILTGAGVGLLSVFVILKFIERLRLP-PGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFY-CDE---LIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR--SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEF 1448
            +L  A +  L+V +++  + + R   PGPWA+P  GN+    G  I+  + +  + +YG++  +  G  PIV ++  +     L  K G++ A R +  +  + S      F   YG  WK   + +K  +       +   N    +  Y C E   L++   +       FD S  +     N V ++  G+ +   D++++ L D    +          ++IP  R++P   ++ L +     ++ +AK V D        NN  +I + L+Q  +  K   +K   L+D  I     DI  A ++ I    +W +  L  +P+ Q++I  +I +     +   P+F  + +L Y +A   E  R SS V     HC      L GY +PKG  +  N Y +NHD   W++ +   PERFLD +G         ++ FGMGVR C G  + +   F+++  +    K+  S+++E 
Sbjct:   15 MLLKASISFLTVLLVMSILWKKRNSLPGPWAVPIVGNFFQL-GDQIHITLTDM-RNRYGDVFQIKLGLMPIVVVSGLETVKRVLL-KEGENFADRPNFYSFSLFSNGSSMTFSEKYGESWKIHKKIMKNALRNLSNESTNSSNCSCRLEEYVCAEASDLVQELTDLSAEKVAFDPSSLIVITVANVVCALSFGKRYDHHDKEFLTLIDFNNDLRKAAGGGLLADFIPILRFIPSSSVKALKKFVQSFHSFIAKCVKDHFATFE-ENNIRDITDALIQLCKERK-SEDKNQLLSDDQIISTVNDIFGAGFDTITSALLWAIFYLLRYPEFQDKIHKEIEEKIGCNR--APRFNDRKDLHYTEAFINEVLRHSSFVPFGLPHCTTMDTKLNGYFLPKGTCVFTNLYQVNHDNTVWKDADMFMPERFLDQNGQIIKSLTEKVLVFGMGVRKCLGEDVARNEMFVIMTIMMQRLKLVKSTKHEL 487          

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALK--------LGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR--SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWS 1433
            L+ PPGPW LPF G+    G N  +   R+ +    +YG+++ +  G+TP+V ++      +AL  + G    GR  + +  +++  +   F  + GP+W    R    ALK           S C     LE+++ K  N+   +L +     G     FD   +L     N + +I  G+ +  +D++ + + +   +  ++       ++IP  RYLP   +    + + K  + + K + +  +    G  R+  D++IE+     ++ KL     V L+D  +  I  D+  A ++ +     W +  L  +P++Q +I+ ++  +  +  D  P+   + +LPY++A   E FR SS V     H   +  +L G++IPKGC + VNQ+ +NHD E W +P   +PERFL  SG    R    +  FG+G R C G +I +   FL L  L    + K S
Sbjct:   41 LKTPPGPWGLPFIGHMLTVGKNPHLSLTRLSQ----QYGDVLQIRIGSTPVVVLSGLNTIKQAL-VRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSC----YLEEHVSKEANYLVSKLQKVMAEVGH----FDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPVLRYLPNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEH----CQDRKLDENANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGR--DRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFKVS 487          

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALK--------LGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR--SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWS 1433
            L+ PPGPW LPF G+    G N  +   R+ +    +YG+++ +  G+TP+V ++      +AL  + G    GR  + +  +++  +   F  + GP+W    R    ALK           S C     LE+++ K  N+   +L +     G     FD   +L     N + +I  G+ +  +D++ + + +   +  ++       ++IP  RYLP   +    + + K  + + K + +  +    G  R+  D++IE+     ++ KL     V L+D  +  I  D+  A ++ +     W +  L  +P++Q +I+ ++  +  +  D  P+   + +LPY++A   E FR SS V     H   +  +L G++IPKGC + VNQ+ +NHD E W +P   +PERFL  SG    R    +  FG+G R C G +I +   FL L  L    + K S
Sbjct:   41 LKTPPGPWGLPFIGHMLTVGKNPHLSLTRLSQ----QYGDVLQIRIGSTPVVVLSGLNTIKQAL-VRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSC----YLEEHVSKEANYLVSKLQKVMAEVGH----FDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPVLRYLPNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEH----CQDRKLDENANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGR--DRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFKVS 487          

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPS--------LEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSK----LVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            L+ PPGPW LPF G+    G N  +   R+ +    +YG+++ +  G+TP+V ++      +AL  + G    GR  + +  +++  +   F  + GP+W    R  +  +    +           LE+++ K  N    +L +     G    P  +      N + ++  G+ F  + E+ + + ++ +   + +     V++ P  RYLP   ++R    +      L K V +  +    +N+  +I   L + +EN K    L+ E+K       I  I  DI  A ++ +     W + LL   P +Q +I  ++  +  +  D  P+   + +LPY++A   E +R++S V     H   +  +L G+HIPK   I +NQ+ +NHD ++W++P   +PERFL ++ +  D++    +M FG+G R C G    K   FL L  L
Sbjct:   38 LKNPPGPWGLPFIGHMLTVGKNPHLSLTRLSQ----QYGDVLQIRIGSTPVVVLSGLNTIKQALV-RQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSASSCYLEEHVSKEANHLVSKLQKAMAEVGH-FEPVSQVVESVANVIGAMCFGKNFPRKSEEMLNIVNNSKDFVENVTSGNAVDFFPVLRYLPNPALKRFKTFNDNFVLFLQKTVQEHYQ-DFNKNSIQDITSALFKHSENYKDNGGLIPEEK-------IVNIVNDIFGAGFDTVTTAITWSILLLVTWPNVQRKIHEELDTVVGR--DRQPRLSDRPQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKERCIYINQWQVNHDEKQWKDPFVFRPERFLTNNNSAIDKTQSEKVMLFGLGKRRCIGEIPAKWEVFLFLAIL 473          

Query:  111 PPGPWALPFWGNYRGFNGAMIYKRM-VEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNN-----YGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSD---NTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFV---NWIP-FGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIK 1427
            PPGPW LPF GN   F+  + +  + ++ +  KYGNL++L +G  P V I+   L  EAL    G++   R        +   R +IF NN      G  WKE  R   + +   GL   SLE+ IQ   +   + +    +  G+   PFD  + +++   N + SI IG  F  ED  +  L     +    ++ S+ +   N  P   +YLP    ++LF    KL  L    V D+ +     + P + I+  L  TE +K   +   + N+ ++     D+ FA  E       W +  + ++P++QE++  +I ++  + +   P  + ++ +PY  AV +E  R  +I+ +         +TL G+H+PKG ++  N  A++ D + W  P+   PE FL+ +G F  R   +PF +G R CPG  + +   F     L   +  K
Sbjct:   44 PPGPWRLPFVGNLFQFDLDVSHLHLGIQPFVKKYGNLISLDFGTIPSVIISGEPLIKEALTCM-GQNFLKRP-------ILAARQHIFKNNGIISSSGQTWKEQRRFTLMILKNFGLGKKSLEQRIQDEAHHLVEAIA---EEKGR---PFDPHFMINNAVSNIICSITIGERFEYEDNQFQELLKLADETL-CLEASKVLMLYNVFPSIFKYLP-GPHQKLFSNWEKLK-LFFSHVMDSHRKDWNPSAPRDFIDAFL--TEMAKYSDKTTTSFNEENLICTTLDLFFAGTETTSTALRWALLYITVNPEVQEKVHSEIDRVIGQGRH--PTIDDRDSMPYTNAVIHEVLRMGNIIPLNVPREVEADITLAGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLE-NGQFKKRESFLPFSVGKRGCPGEQLARSELFTFFTALMQKFTFK 474          

Query:  111 PPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSD---NTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIM-----DKSEFVNWIPF-GRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNY 1418
            PPGPW LPF GN    +    +  +    K KYGN+ +L  G+   V I    L  EAL       +    SV  E I S +   IF +  G +WKE  R   + +   GL   SLE+ +Q+  + +  E IR  +  GK   PF+  + +++   N + S+  G  F   D  +   Q+  R + ++M       S+  N  P+  +Y+P    +++F    KL   ++  + D RK     + P + I+  L+E        EK  + N+ ++     D+ FA  E    T  W +  + L+P++QE+++ +I ++  +K+ +  +   +  +PY  AV +E  R  +I+ +           L G+H+PKG ++  N  A++ D + W  P+   PE FL+ +G F  R   +PF MG R C G  + +   F+   +L   +
Sbjct:   44 PPGPWGLPFVGNIFQLDFGQPHLSIQPLVK-KYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERI-SNKNGLIFSS--GQIWKEQRRFALMTLRNFGLGKKSLEERMQEEAS-HLVEAIR--EEEGK---PFNPHFSINNAVSNIICSVTFGERFDYHDSRF---QEMLRLLDEVMYLETTMISQLYNIFPWIMKYIP-GSHQKVFRNWEKLKLFVSCMIDDHRK-DWNPDEPRDFIDAFLKEMTK---YPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAA--RLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLE-NGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKF 468          

Query:  102 LRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALK--------LGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKM---GRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR--SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWS 1433
            L+ PPGPW LPF G+    G N  +   R+ +    +YG+++ +  G+TP+V ++      +AL  + G    GR  + +  +++  +   F  + GP+W    R    ALK           S C     LE+++ K  N+   +L +     G     FD   +L     N + +I  G+ +  +D++ + + +   +  ++       ++IP  RYLP   +    + + K  + + K + +  +    G  R+  D++IE+     ++ KL     V L+D  +  I  D+  A ++ +     W +  L  +P++Q +I+ ++  +  +  D  P+   + +LPY++A   E FR SS V     H   +  +L G++IPKGC + VNQ+ +NHD E W +P   +PERFL  SG    R    +  FG+G R C G +I +   FL L  L    + K S
Sbjct:   41 LKTPPGPWGLPFIGHMLTVGKNPHLSLTRLSQ----QYGDVLQIRIGSTPVVVLSGLNTIKQAL-VRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSC----YLEEHVSKEANYLVSKLQKVMAEVGH----FDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPVLRYLPNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEH----CQDRKLDENANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGR--DRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFKVS 487          

Query:   51 AGVGLLSVFVILKFI-----ERLRLPPGPWALPFWGNYRGF--NGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKE----MIRALKLGVSKCGLTP----SLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            A V L  V++I+K++     E L+  PGP  LP  GN      N  +    M E    +YG++  +  G  P+V ++  +   +AL  K G+  AGR  + +   +++ +   F  +   +W+      + AL+   +  G TP    +LE+++ K   +   +L    D SG    PF        N +  +  GR ++ +D++ + L +   +   ++      ++IP  RYLP + ++R  + + + NN + K VS+  +    ++N  +I + L+   E+ KL     + ++D  I  I  D+  A ++ I     W +  L  +P+ QER+  ++ +     +  TP+   K  LP ++A   E FR SS +     HC +K  +L GY IPK   + +NQ+ +NHD E W+ P +  P+RFL + G   ++ +   ++ FGMG R C G +I +   +L L  L
Sbjct:   20 AMVTLCLVYMIMKYMHTEIPEGLKRLPGPKPLPIIGNMLEVHNNPHLSLTAMSE----RYGSVFQIQIGMRPVVVLSGNETVRQAL-IKQGEDFAGRSDLYSFKFINDGKSLAFSTDKAGVWRARRKLAMSALRSFATLEGTTPEYSCALEEHVLKEGEYLVKQLTSVMDVSG-SFDPFRHIVVSVANVICGMCFGRRYSHDDQELLGLVNMSDEFGQVVGSGNPADFIPILRYLPNRTMKRFMDINDRFNNFVQKIVSEHYE-SYDKDNIRDITDSLIDHCEDRKLDENANIQVSDEKIVGIVNDLFGAGFDTISTALSWAVVYLVAYPETQERLHQELKEKVGMIR--TPRLSDKINLPLLEAFILEIFRHSSFLPFTIPHCTIKDTSLNGYFIPKDTCVFINQWQVNHDPELWKEPSSFNPDRFLSADGTELNKLEGEKVLVFGMGKRRCIGEAIGRNEVYLFLAIL 480          

Query:   72 VFVILKFI-----ERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALKLGVSKCGLTPS----LEKNIQKSINFYCDELIRNPDNSGKGVF-PFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            V++ILKF      E LR  PGP  LP  GN     G+  Y  +    K +YGN+  +  G  P+V ++  +   +AL  K G   AGR  + +   ++E +   F  +   +W+   +    AL+   +  G TP     LE+++ K   +   +L  N   +  G F PF        N +  +  GR +  +D++ + L     +   ++      ++IP  +YLP   ++     + +    + K V++       ++N  +I + L+   E+ KL     V ++D  I  I  D+  A ++ +     W +  L  HP+IQER+  +I        D  P    K  LP+++A   E  R SS +     HC  K  +L GY IPK   + +NQ+ INHD E W++P +  P+RFL + G+  ++ D   +M FGMG R C G  I +   +L L  L
Sbjct:   27 VYLILKFFQTEIPEGLRRLPGPKPLPIIGNVLEM-GSRPYLSLTAMSK-RYGNVFQIQIGMRPVVVLSGSETVRQAL-IKQGDDFAGRPDLYSFRFINEGKSLAFSTDKAGIWRARRKLAYSALRSFATLEGTTPEYSCVLEEHVCKEGEYLIKQL--NTAMTADGSFDPFRHIVVSVANVICGMCFGRRYDHDDQELVGLVTLSDEFGRVVGSGNPADFIPILQYLPSATMKNFLRINGRFTEFVQKIVTEHYTTFD-KDNIRDITDSLIDHCEDRKLDENSNVQMSDEKIVGIVNDLFGAGFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGL--DRMPLLSDKPNLPFLEAFILEILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPEMWKDPSSFNPDRFLSADGSEVNKLDGEKVMAFGMGKRRCIGEVIARNEVYLFLAIL 480          

Query:   51 AGVGLLSVFVILKF-----IERLRLPPGPWALPFWGNYRGF--NGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKE----MIRALKLGVSKCGLTP----SLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            A V L  V++++K+      E L+  PGP  LP  GN      N  +    M E    +YG++  +  G  P+V ++  +   +AL  K G+  AGR  + +   +++ +   F  +   +W+      + AL+   +  G TP    +LE+++ K   +   +L    D SG    PF        N +  +  GR ++ +D++ + L +   +   ++      ++IP  RYLP + ++R  + + + NN + K VS+  +    ++N  +I + L+   E+ KL     + ++D  I  I  D+  A ++ I     W +  L  +P+IQER+  ++ +     +  TP+   K  LP ++A   E FR SS +     HC +K  +L GY IPK   + +NQ+ +NHD E W+ P +  P+RFL + G   ++ +   ++ FGM  R C G +I +   +L L  L
Sbjct:   20 AIVTLCLVYMLMKYKHTEIPEGLKRLPGPKPLPIIGNVLEVYNNPHLSLTAMSE----RYGSVFQIQIGMRPVVVLSGNETVRQAL-IKQGEDFAGRPDLYSFKFINDGKSLAFSTDKAGVWRARRKLAMSALRSFATLEGTTPEYSCALEEHVCKEGEYLVKQLTSVMDVSG-SFDPFRHIVVSVANVICGMCFGRRYSHDDQELLGLVNMSDEFGQVVGSGNPADFIPILRYLPNRTMKRFMDINDRFNNFVQKIVSEHYE-SYDKDNIRDITDSLIDHCEDRKLDENANIQVSDEKIVGIVNDLFGAGFDTISTALSWAVVYLVAYPEIQERLHQELKEKVGMIR--TPRLSDKINLPLLEAFILEIFRHSSFLPFTIPHCTIKDTSLNGYFIPKDTCVFINQWQVNHDPELWKEPSSFNPDRFLSADGTELNKLEGEKVLVFGMDKRRCIGEAIGRNEVYLFLAIL 480          

Query:   51 AGVGLLSVFVILKFI-----ERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNL 1406
            A V +  V++I+K       E L   PGP  LP  GN     G+  Y  + E  K +YGN+  +  G  P+V ++  +   +AL  K G   AGR  + +   +SE +   F  +   +W+   +    AL+   +  G TP     +++ I+   + LI+  D   K    FD   ++     N +  +  GR +   D + + L +   +   ++      ++IP  +YLP K +++    + +  + + K VS+       ++N  +I + L+   E+ KL     V ++D  +  I  D+  A  + I     W +  L  +P+IQER+  ++ +  +   D TP    +N LP ++A   E FR SS +     HC  K  +L GY+IPK   + +NQ+ INHD E W+ P +  P+RFL + G   ++ D   +M FG+G R C G  I +   ++ L  L
Sbjct:   20 ALVTVCLVYLIIKSFQANIPEGLSRLPGPKPLPIIGNVLEV-GSRPYLSLTEMSK-RYGNVFQIQIGMRPVVVLSGNETVRQAL-IKQGDEFAGRPDLYSFRFISEGKSLAFSTDQAGVWRARRKLAYSALRSFSTLEGTTPEYSCVLEEHISKEAEYLIKQLDTVMKADGSFDPFRYIVVSVANVICGMCFGRRYDHHDRELLSLVNLSDEFGQVVGSGNPADFIPILQYLPNKTMKKFVNINDRFISFVQKIVSEHYATFN-KDNIRDITDSLIDHCEDRKLDENANVQMSDEKVVGIVNDLFGAGLDTISTALSWSVMYLVAYPEIQERLYQELKE--NVGLDRTPVLSDRNNLPLLEAFILEIFRHSSFLPFTIPHCTTKDTSLNGYYIPKDTCVFINQWQINHDPELWKEPSSFNPDRFLSADGTEVNKVDGEKVMVFGLGKRRCIGEVIARNEVYMFLAIL 480          

Query:   27 MWQDILTGAGVGLLSVFVILKFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVN-LNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR-SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNY 1418
            MW   +T   V L+    +  +++R R+PPGP+  P  GN   F+G M Y    +  K KYG++ +L  G T +V +N      EA   K G   AGR  + + DI SE   +I   +Y P WK   +     +    L  +L+  + +S+     E  +     G+ V   D  Y L  N + S   G  +T++DE++  L    +   +I+ +    +  P  R+LP   +  + + + +   ++ + + + R+     N  D I +++++  ++++    + +N L D H+RQ   DI     +    T  W +  L +HP+IQE++  ++  +  +  D  P+   +   PY +A   E  R  SI  +   H      TL GY IPKG  +  N +A++ D + W +P+  +PERFLD +G    + + +MPF  G R CPG ++ K   FLLL  L  N+
Sbjct:    1 MWLMTITVGLVTLVLATWLRDYVKRWRMPPGPFFWPIIGNIYFFSGRM-YTTCTDLAK-KYGDVFSLKMGMTDVVVLNSLDTVKEAF-VKKGVDFAGRPKILSMDIFSEGGKDIAFTDYSPTWKLHRKLFHGAIRGYALGENLQTRVHESLEDTIAEFTKM---EGQAVNIEDYIYQLVYNVICSAAFGVRYTMDDEEFNTLMKINKDTEEIVGQGLLADVYPSLRFLPSPTLTNIRKMTKQYVGIMQRHLEEHRETFDPSNLRD-ITDHMIKAQKDAEEEGIQDINSLTDTHLRQTISDIFGGGTDTTIFTLRWAILYLAVHPEIQEKVAAELDSVVGR--DRLPELSDREATPYTEATILEVMRMGSIAPLSLPHATTVDTTLRGYQIPKGTWVVPNLWALHRDPDTWGDPDVFRPERFLDENGKPVPKPAALMPFSAGRRACPGEAVGKADTFLLLGGLVQNF 457          

Query:   48 GAGVGLLSVFVILK-FIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLP-----LKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVN-LNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR-SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYK 1421
             AG+  L +   L+ +++R R+PPGP+  P  GN    NG M Y   ++  + KYG++ +L  G T +V +N      EA   K G   AGR  + + +I++E   +I   +Y P WK + R L  GV+  G   +L+  + +S+    D +       G+ V      Y L  N + S   G  + ++DED+I L    + + + + +    +  P  R+LP     L   R++ EQS     +L + + + R+     N  D I +++++  ++++    + +N L D H+RQ   D+     +    T  W    L  HP+IQE++  ++  +  +  D  P+   +  +PY +A  +E  R  SI  +   H      TL GY IPKG  I  N +A++HD + W +P+  +PERFLD  G    + + +MPF  G R CPG ++ K   +LLL  L  N++
Sbjct:    4 AAGIVTLLLLTWLRDYMKRWRMPPGPFFWPIIGNIY-CNGRM-YITFIDLAQ-KYGDVFSLKMGMTDVVVLNSLDAVKEAF-VKKGVDFAGRPKILSNEILTEGGKDIAFTDYSPTWK-LHRKLFHGVTHWG--QNLQTKVHESLE---DTIAEFSKMEGQAVDLEGYIYKLVYNVICSTAFGVRYNMDDEDFITLMKISKDMTETLGQGLLADVYPSLRFLPSPGESLTAFRKMTEQSL---TILQRHLEEHRETFDPSNLRD-ITDHMIKAQKDAEEEGIQDINSLTDTHLRQTMNDVFAGGTDTTIWTLRWANLYLAAHPEIQEKVAAELDSVVGR--DRLPEMSDREAMPYTEATIHEIMRMGSIAPLSLPHATTVDTTLSGYQIPKGTWIMPNLWALHHDPDTWGDPDVFRPERFLDEDGKPIPKPAALMPFSAGRRACPGDAVAKAVTYLLLGGLVQNFR 453          

Query:   27 MWQDILTGAGVGLLSVFVILKFIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDAR-KMGRYR-----NNPDNIIEYLLQETENSKLVTEKKVN-LNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRS-DIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVL 1484
            MW   L+ + + ++ V  ++ +I+R R+PPGP+  P  GN   F+G   +   ++  K KYG++ +L  G T +V +N      EAL  K+    AGR  +Q+ +I+SE R ++   +Y P WK+  + +K  + +C     LE     ++    DEL+     +       +   +   N V  I  G  F LE+ED+  L  +     D    S   +  P  R+LP +         T L  L   FV   + ++ R+R     +NP ++ +++++  + ++      +  L D H+RQI  D+     E       W +     HP+IQE++  ++  +  +  D  P    +   PY +A   E  R      +       +  +L GYHIPKG ++  N +A++HD + W +P T +PERFLD SG    +    MPF +G R CPG  +     +LLL  L  N+   +    E  +  D P   V+
Sbjct:    1 MWLITLSVSLLVVMFVNWLMDYIKRWRMPPGPFPWPIIGNLSMFSGKS-HLTFIDLAK-KYGDVFSLKRGMTDVVVLNSVDAVREALVEKSVA-FAGRPHLQSTEIMSEGRRDMAYTDYSPAWKQHRKLIKSALRECASDKKLETQAHAALRDIIDELVSVESQAVDLHMHINNLVY---NVVCPIAFGVRFDLENEDFQHLAGTEE---DTYSNSPVGDIYPSLRFLPNRA-------KTNLQKLTGPFVEYFKHQVDRHRQEFNPDNPRDVTDHMIKAQKEAEEDGAHDITALTDTHLRQIVVDVFSGGTETTTHALRWAIQFFAAHPEIQEKVAAELDSVVGR--DRLPGLGDRQNTPYTEATVNEVLRMGIPDPLSLPRATTQDTSLRGYHIPKGTMVLPNLWALHHDPDIWGDPHTFRPERFLDESGKLMPKPFAWMPFCVGRRACPGEKMGMADTYLLLGGLVQNFHFSFPG-GERPDDADAPYKVVV 475          

Query:   90 FIERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVN-LNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD-IMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDY 1505
            ++ R R+PPGP+  P +GN   F G   Y   ++  K KYG++ +L  G T +V +N      EA   K G   AGR +  + DI +E   +I   +Y P WK   +     +       +L+  + +S+     E  +     G+ V   D  Y L  N + S   G  + ++D+D+  L    +   ++  +    +  P  R+LP   I  + +      +++   +   R+     NN  +I +++++  ++++    + +N L D H+RQ   DI     +   +T  W +  L  HP+IQE++  ++  +  +  D  P+   +   PY +A  +E  R  SI      H      TL G+ IP+G  I  N +A++HD + W +P+  +PERFLD +G    +   +MPF  G R CPG ++ K   FLLL  L  N+           +L  D +   +   P  Y
Sbjct:   22 YVRRWRMPPGPFFWPIFGNLSLFAGK-FYLTFIDLAK-KYGDVFSLKQGMTDVVVLNSLDAIREAF-VKKGVEFAGRPTFVSADIFTEGGKDIAFTDYSPTWKLHRKLFHTAIRGYASGENLQNKVHESLEETIAEFSKM---EGQAVDLEDYIYKLVYNVICSAAFGVRYNMDDKDFNTLMKVSKDSAEVFGEGILADVFPSLRFLPTPGITAIQKIVRPFLDIMQHHLDQHRETFD-PNNLRDITDHMIKAQKDAEEEGMQDINSLTDTHLRQTIADIFGGGTDTTILTLRWAVLFLSAHPEIQEKVAAELDSVVGR--DRLPELSDREATPYTEATIHEVMRMGSIAPSSLPHTTTVDTTLRGHRIPQGTWIMPNLWAVHHDPDTWGDPDVFRPERFLDENGKPIPKPPALMPFSAGRRACPGEAVGKADTFLLLGGLVQNFCFSIPEGEGPPDLTPDEKGGGVTSLPSPY 486          

Query:  207 YGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVN-LNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR-SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYK 1421
            YG++ +L  G T +V +N      EA   K G+  AGR  + + DI SE   +I   +Y P WK   +     +       +L+  + +S+    D +       G+ V   D  Y L  N + S   G  + ++DED+  L    +   +   +    +  P  R+LP   +    + + +L  ++ + +   R+     NN  +I +++++  ++++    + ++ L D H+RQ+  DI FA      +T  W +  L +HP+IQE++  ++  +  +  D  P+   +   PY +A+ +E  R +S+  +   H      TL GY IPKG  I  N +A++HD + W +P+  +PERFLD SG    + + +MPFG+G R CPG ++ K   FLLL  L  N++
Sbjct:   11 YGDVFSLKMGMTDVVVLNSLDAVKEAF-VKKGEDFAGRPKMLSTDISSEGGKDIAFADYSPTWKLHRKLFHSAIRGYASAQNLQSKVHESLE---DTIAVFSKMEGQAVDLEDYIYQLVYNVICSAAFGTRYNMDDEDFNTLMKISKDTTETFGQGLLADVYPLLRFLPSSSVTANRKMTHQLMEIMQRHLEQHRE-SFDPNNLRDITDHMIKAQKDAEEEGIQDIDSLTDTHLRQLIGDIFFAGTISTILTLRWAILYLAVHPEIQEKVAAELDSVVGR--DRLPELSDREATPYTEAIFHEVMRMASMDPVSLPHATTVDTTLRGYQIPKGTWILPNLWALHHDPDTWGDPDVFRPERFLDESGKPIPKPAALMPFGVGRRACPGEALGKADTFLLLGGLVQNFR 410          

Query:   51 AGVGLLSVFVIL-----KFIERLRLPPGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALKLGVSKCGLTP----SLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSS 1436
            A V +  V+++L     K  E L+  PGP +LP  GN    G+N  +    M E    ++G++  +  G+ P+V ++  +   +AL  K G   AGR  + +   +++ +   F  +   +W+   +    AL+   +  G TP    +LE++I K    Y  E +R    +     PF        N +  +  GR ++ + E+ + L +   +   ++      ++IPF R LP K +++  + + + N  + K + +  +    +NN  +I + L+   E+ KL     V ++D  I  I  D+  A ++ I     W +  L  +P+I E++  ++ +     +  TP+   K  LPY+     E FR SS +     HC  K  +L GY IPK   + +NQ+ INHD ++W+ P    P+RFL   G   ++++   +M FG+G R C G  I +   FL L    L  ++K+SS
Sbjct:   20 AMVTICIVYILLQKSRVKIPEGLKQLPGPHSLPIIGNLMELGWNPHLSLTAMSE----RFGHVFKIHIGSRPVVVLSGSETVRQAL-IKQGDEFAGRPDLYSFQYINDGQSLAFSTDQAGVWRHRRKLAQNALRSFATLKGQTPEYSCALEEHISKE-GLYLVERLRKVTKADGCFDPFRHIVVSVANVICGMCFGRRYSHDHEELVSLVNLSDEFGQVVSSGNPADFIPFLRLLPSKTMKKFVDINNRFNKFVQKILREHYETYD-KNNIRDITDSLIDHCEDRKLDENSNVQVSDEKIVGIVNDLFGAGFDTISTALSWSVMYLVAYPKIHEKLYQEMMEKIGTGR--TPQLSDKTNLPYLDCFITEVFRHSSFLPFTIPHCTSKDTSLNGYFIPKDTCVFINQWQINHDPDQWKEPSMFNPDRFLSEDGVEINKTEAEKVMVFGLGKRRCIGEYIGRSEVFLFLT--ILIQRLKFSS 488          

Query:   51 AGVGLLSVFVILKFIERLRLP------PGPWALPFWGNYR--GFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIR----ALKLGVSKCGLTP----SLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSS 1436
            A V + +V+++++ + R R+P      PGP ++P  GN    G N  +    M +    ++GN+  +  G  P+V ++  +   +AL  K G   AGR  + +   ++  +   F  +   +W+   +    AL+   +  G TP    +LE++I K    Y  E +R    +     PF        N +  +  GR ++ + E+ + L +   +   +       ++IPF R+LP K +    + + + N  + + V +  +    +NN  +I + L+   E+ KL     V ++D  I  I  D+  A ++ +     W +  L  +P+IQE++  ++ +      D  P    KN LP +++   E FR SS +     HC  K  +L GY IPK   + +NQ+ INHD ++W+ P    P+RFL   G   ++++   +M FG+G R C G  I +   FL L    L  ++K+SS
Sbjct:   20 AMVAICTVYLLVQ-LSRERIPAGLKLLPGPQSIPIIGNVMELGLNPHLSLTTMSK----RFGNVFKIHIGTRPVVVLSGGETVRQAL-IKQGDDFAGRPDLFSFQYINNGKSLAFSTDQAGVWRHRRKLAQNALRSFSTLEGQTPEYSCALEEHISKE-GLYLVERLRKVTKAEGCFDPFRHIVVSVANVICGMCFGRRYSHDHEELVSLVNLSDEFGQVAGNGNPADFIPFLRFLPSKTMETFVDINRRFNKFVQRIVREHYETYD-KNNIRDITDSLIDHCEDRKLDENSNVQVSDEKIVGIVNDLFGAGFDTVSTALSWSVMYLVAYPEIQEKLHQELMEKVGN--DRKPCLTDKNNLPLLESFITEMFRHSSFMPFTIPHCTTKDTSLNGYFIPKNTCVFINQWQINHDPDQWKEPSMFNPDRFLSEDGVEINKTEAEKVMVFGLGKRRCIGEYIGRSEVFLFLA--ILIQRLKFSS 488          

Query:   45 TGAGVGLLSVFVILKFIERLRL-------PPGPWALPFWGNYRGF-NGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYI----ILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKW 1430
            T  G+ L+   V L  +E LRL       PPGP  L F GN   F    M + R +    PKYG + +L+ G  P + +N  ++A EA   +NG   +GR S+     V++  + I    YG  W++  R     +   GL   S+E+ + +  +F   E+++     GK  +P         N + SIV G  F  +D  +     I+ ++ R  F     ++  N +P  +Y P    ++++     L   +++ V   RK     N  D I  YL+   E +K  + +    ++ ++ +   D+  A  E    T  W +  +  HP +QER   +I ++     D  P  + + +LPY  A  +E  R+++IV +   H   +   L GYHIP G  I  N  AI  D + W+ P+T  PE FLD  G F      +PF +G R+C G ++ +   F+   +L    K  W
Sbjct:   11 TSVGLALVGGLVSLVLLEILRLNSSRSRSPPGPKPLLFVGNMPQFIKDKMGFIRSM----PKYGEISSLYLGRKPTIILNTMQVAKEAFV-QNGTIFSGRPSLPLVRWVNKG-YGIVMATYGNSWRQQRRFALHTLRDFGLGKKSVEERVAEEAHFLIKEMLKQ---EGKAFYPIHPIMNSVSNIICSIVFGDRFEYDDRRFAKLLEIINENIR--FSGSPVAQIFNLVPIIKYFP-GPHQKIWHNLQSLRKFMSEEVEKHRKSLDPENLRDFIDAYLV---EMNKQESNEDSTFHEENMLRSTTDLFIAGTETTANTLRWGLIYMMEHPDVQERCHEEIVRVLGF--DRFPSMDDRAQLPYTHATVHEIQRYANIVPLGVVHQTTQPTKLRGYHIPAGTNIMSNLTAILTDKDHWKYPDTFNPENFLDEKGQFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQQLKFSW 468          

Query:  111 PPGPWALPFWGN-YRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDK--SEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKW 1430
            PPGP +LP+ GN  + F   M   R +E     YG +  LF G  P++ +N  ++  EA  N NG   +GR  V   + V+     I    YG  WK+  R     +   GL   S+E+ + +   +  +E++++    GK  FP         N + SIV G  F  ED+ +  L     +   +      +  N  PF ++ P    +++   +  L   + + V + RK     N  D I  YL++ T+  K + E   +  ++ I     D+  A  +    T  W +  +  HP +QER   +I ++     D +P  + + +LPY  A  +E  R S+I+ I   H   +S  L GYHIP G  I  N  AI  D   W++P+   PE FLD  G F      +PF MG R+C G S+ +   F+   +L    K  W
Sbjct:   40 PPGPKSLPYVGNVMQLFKEPMDLIRSME----NYGEMSCLFLGRKPMIVLNKMEIVKEAFVN-NGSVFSGRPQVPLLEWVTNGL-GIVMAPYGNSWKQQRRFALHTLRDFGLGKKSVEERVAEEARYLVEEMLKH---EGKAFFPIHPIMNSVSNIICSIVFGDRFDYEDKRFAHLLKLLNEYVGLPGSMIGQIFNLAPFIKHFP-GPHQKVLRNANSLKGFIREIVEEHRKTLDPENLRDFIDAYLVEMTKQ-KAMEESTFHEENMIIST--TDLFLAGTDTTATTLRWGLIYMMDHPDVQERCHNEIVRVLGF--DRSPCMDDRAQLPYTHATIHEILRCSNIIPIGPPHETTQSTQLHGYHIPAGTQILANSTAIMTDRNHWKHPDVFNPENFLDEKGQFCKNDFFLPFSMGQRVCLGESLARTELFIFFTSLIQRLKFSW 468          

Query:   30 WQDILTGAGVGLLSVFVILKF---IERLRLPPGPWALPFWGNYRGFN-GAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNP-DNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDI--MDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKW 1430
            W  +      G+LS+F++  F     R + PPGP  LPF GN       AM + R +     KYG+L  L+  N P++ +N   +  E    +NG   AGR  V   D V+   + I    YG  WK+  R     +   GL    ++N+++ +      LIR    + GK   P  +      N + SIV G  F  +D+ +  L +   +   +     +  V  +PF R+ P    +++++    L   + + V + RK     N  D I  YL+   E SK  + +    N+ ++     D+  A  +    T  W +  +  HP +QER   +I ++     D +P  + + +LPY QA  +E  R + I+  +  H   +   LG YH PKG  I  N      D + W++P+T  PE FLD  G        +P+ +G RMC G ++TK   F+   +L    K  W
Sbjct:   10 WMSVGLALLAGVLSLFLLEIFRLNSSRRQNPPGPKPLPFVGNLPQLKKDAMAFVRSMA----KYGDLSCLYLANKPVIVVNSLPMVKETFV-QNGGAFAGRSPVPILDFVTNG-YGIIMAPYGISWKQQRRFALHTLRNFGLG---KRNVEERVAEEAQYLIRELLTHEGKSFCPIHKIMNAVSNIICSIVFGDRFEYDDKRFSKLLEIINENIQLSGAPATRMVYVVPFIRHFP-GPHQKVWQNVKSLKEFIREAVEEHRKTLHPENPRDFIDAYLV---EMSKQQSNEDSTFNEENMIMSTSDLFLAGTDTTASTLKWGLIYMMDHPDVQERCHEEIVRVLGF--DRSPCMDDRAKLPYTQATIHEIQRCADIIP-MAIHETTQPTQLGEYHFPKGTKIMPNLAIFLADRKHWKHPDTFNPENFLDEKGQSCKSEYFLPYSLGSRMCVGETLTKAELFIFFTSLIHRLKFSW 467          

Query:   30 WQDILTGAGVGLLSVFVILKFIER------------LRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSD---NTVLSIVIGRTFTLED---EDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRF---PKDYLLNI 1517
            W   L    +  L++F I+  + R            L  PPGP  +PF GN   F    +    ++    +YG + ++  G   +VF++ Y+   E L ++ G   A R +      V+     IF   YG  W +  R     +   GL   S+E+ IQ  + F    LI      G     FD  Y L+    N + S+V G+ +   D   +D++ L ++  Q+   +  +   N  PF    P    + +F+   K    +   +S+ R   R    P  +I+  L + E          + ++  +  +  D+  A  E    T  W +  + +HP+IQ +   +I K+     D  P  E ++ LPY+ AV +E  RFS+IV     H     V    Y IPKG +I VN  ++  D   W+ P    PE FLD  G F      +PF  G R+C G ++ K   FL   +L  +++  W       +LV  P    + +    PK Y L +
Sbjct:   15 WSSFLGHQALISLAIFCIIFLVLRAILQEVKATKRPLDFPPGPKVIPFLGNVSLFKKPDV---ALDEVTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQ-GHEFADRPNTPFNKKVNGGLGIIFAP-YGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGF----LIEAFKQKGSA---FDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLGT-LCNIFPFLMDFP-GPQQIIFKSMAKSKQFIRDIISE-RHATRDPIKPMCLIDAYLSQLEKED---NPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGS--DRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFLDEDGKFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWP------DLVSAPTLGYILQITKAPKSYKLGL 506          

Query:  114 PGPWALPFWGNYRGF--NGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKN----IQKSINFYCDELIRNPDNSGK---GVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSD---ARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR---SDIMPFGMGVRMCPGTSITKGYGFLLLCNLC--LNYKIKWSSENEFTELVDDPENAVLFRFPK 1499
            PGP   P  GN      +  +   RM +    +YG++  +  G+ P+V ++  +    AL  KNG   AGR    +  +V       F   Y   WK   R  +  +      P+  +     +++ +    + L+      G    G  P         N + ++V G+ +   D  ++ +     +   +      V++ PF R++P   +R L   S +L   +   + +   + + G  R+  D +I  +  E E++     ++V L+D  +     DI  A ++ I     W +  L +HP +Q +++ +I +  +  +D TP+FE +  L  ++A   E FR S+ V     H   + V L G  IP+   + VN + +NHD   W +PE   P+RFL   G   ++     +  FG+G R C G  + +   F++L  L   L++++   +          P++A++ + P+
Sbjct:   59 PGPVRWPIVGNILQLWPDPHLKLTRMCD----RYGDVFRVHLGSVPVVVLSGLETIKRAL-VKNGDAFAGRPPFYSLSLVGNGDTLTFTRAYDGCWKAHKRLARSALRNFCAAPARREGYACLLEECVCEEAERLLLACKGGGAQPGGFDPVPSITCAVANVMCALVFGKRYPHGDPTFLQIVGFNEEASQLSGAGNLVDFFPFLRHVPNAQLRALKVLSARLLAFMEGHIKEHYSSYQKGHVRDITDALIA-MCAEQEHAL----REVGLSDERVVATALDIFGAGFDTIITGLTWCLLYLCIHPDVQHKLQREIDE--TIGRDRTPRFEDRANLRRVEAFLTEMFRHSAFVPFTIPHSTTQDVVLNGMFIPRDTCVFVNLHQVNHDPTVWSDPERFDPDRFLSHDGKEVNKEMVEKVQIFGLGKRRCLGDMVARQELFVVLVTLLQGLSFRVPPGTPTPSVA----PQHALVMKPPR 521          

Query:  114 PGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNI--FGNNYGPLWKEMIRALKL------GVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSD---NTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFV--NWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKW 1430
            PGP  LP  GN   F+    +  M E  K KYG + T+  G+TP+V ++ Y+   E L N+ G   A R       + ++  HNI      YG  WK+  R   L      G  K  +T  +    +  I  +  E              FD  + L+    N + S++ G  +   +E +  L      +  +  +   +  N  PF   LP    +++F   TKL  LL   VS+ R   + ++NP ++I+  L   +  K       +  D  +  +  ++     E    T  W +  + ++P IQ R   +I K+   ++   P  + +  LPY+ AV +E  RF +I+     H   K V    Y  PKG  + VN  +  +D   W+ P    P+ FLD  G        +PF  G  +C G S+ K   FL   +L  +++  W
Sbjct:   36 PGPKPLPLLGNITAFSCKNPHIGMQELAK-KYGEVCTIMLGSTPVVLVSGYQAVKEVLVNR-GHEFADRP---ITPLFTKLTHNIGIALAPYGDTWKQQ-RGFALSTLRNFGFGKATITDKISIEARYLIETFKQETSE-----------FDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVFPFLIKLP-GPWQKVFHIHTKLQCLLKDIVSEHRAT-KDQHNPRDLIDSYLAHIDKEK--DNPNRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQR--PPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFLDKDGQCIKSDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFEFYW 464          

Query:  204 KYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNI--FGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFV--NWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKW 1430
            KYG + T+  G+TP+V ++ Y+   E L N+ G   A R       I ++   NI      YG  WK+  R     +   G     +  I   I+     LI           P         N +  ++    +  ++E +  L      +  +  +   +  N  PF   LP    +++F   +KL  LL   VS+ R   + ++NP ++I+  L + +  K       +     + QI  ++     E    T  W +  + ++P IQ R   +I ++   ++   P    +  LPY+ AV +E  RF +++ +   H   K V    Y  PKG  + VN  +  HD   W+ P    P+ FLD  G        +PF  G R+C G S+ K   FL   +L  +++  W
Sbjct:   69 KYGEVCTIMLGSTPVVLVSGYEAVKEVLVNR-GHEFADRP---ITPIFTKLTQNIGIALAPYGDPWKQQRRFALSTLRNFGFG---KATIADKISIEAKYLIETFKQETSAFDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFPFLLKLP-GPWQKVFHIHSKLQCLLNDIVSEHRAT-KDQHNPRDLIDSYLAQIDKEK--DNPNSSFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSER--PPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFLDKDGQCIQSDAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYW 468          

Query:  567 NTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMD--KSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQ-ERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKW 1430
            N + SIV G  F  +D+ +  L     + F I    + +   ++P+    P    + +F  + K+N    + + + R+  R    P ++I+  L E E  K   + +    D ++  +  D+  A  E    T  W +  +  +PQIQ ER + +I ++     D +P    +  LPY  AV +E  R +++  +   H     V   GY+IPKG  + +N  ++ HD  +W+ P    P+ FLD++G F      + F  G R+C G ++ +   FL   +L   +K  W
Sbjct:   16 NIICSIVFGNRFDYDDKRFRNLLHLFAENFRIEGGWRGKICIFMPWLEDWP-GPHQLIFRNADKVNLFFQERIREHRQT-REAGQPRDLIDAYLDEME--KESQDPESTFTDGNLLNVVGDLFIAGTETSSTTLRWALLYMMAYPQIQAERCQREIDEVIGG--DRSPNTTDRANLPYTDAVIHEAQRMANVAPLGVLHSTTTDVKFRGYNIPKGTKVLLNLTSVLHDETQWKTPNEFNPDHFLDNTGQFVKPDAFLAFSAGPRVCLGENLARMELFLFFTSLLQRFKFHW 300          

Query:  927 LFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTS 1367
            LFAS +       W   ++   P +  +IR +   + +    +    +   ++ Y   V  E  R+   V ++ +           Y  PKG ++    Y   HD E +ENP+   PER+++ S A   + + + FG G  +C G +
Sbjct:  334 LFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQT 480          

Query:  381 YGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDE-SYWLSDNTVLSIVIGRTFTLEDEDYIILQDS----RRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHP-QIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGG-YHIPKGCLIAVNQYAINHDAERW-ENPETIKPERFLDSSGAF-------TDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTE 1454
            YG +W+    A+  G+      P     I K+    C  LI+N    G+   P    S  ++ + +  + +G  F     +     +     ++Q+F       F    PF   LP+   ++ F+       LL K V D   +  Y+          L    N++++  K++  N V        IL A +E   +     + LL  +  + QE++R ++  +   K  +        +LP + A  +E  R    +  +   C  K+  LG    IPKG  +  N +  +HD + W    +  KPER+               +R  +  F  G R C G  +      + L  +   +  +WS + E+ E
Sbjct:  123 YGAVWRNYRNAVTNGLQHFDDAP-----IFKNAKILCT-LIKNRLLEGQTSIPMGPLSQRMALDNISQVALGFDFGALTHEKNAFHEHLIRIKKQIF-----HPFFLTFPFLDVLPIPSRKKAFKDVVSFRELLVKRVQD-ELVNNYKFEQTTFAASDLIRAHNNEIIDYKQLTDNIV-------IILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGLA--------DLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQF--RWSLDPEWEE 466          

Query:  114 PGPWALPFWGNYRGFNGA--MIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVS-----KCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAK--------FVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD--IMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWS 1433
            PGP  LP  GN    +    +   R+   Y P Y    TL  G+   V +N Y++A EAL  K G   AGR         S     +   NY P  +   + +   V      K G   +L++ I   +++ CD  +    +  +   P  +  + + N V  I  G  FT+E+E++  L DS +   + +  + F++  P  RY P   ++R+       +++L K           D   + + ++    +IE   Q+T  +   ++  + L D H+     D + A  E   M  +W +     +P +Q R    I K+ S  +  T  +E +  LPY++A   E  R  SI+ +   H A+  + L GYHI KG  + VN +A+ HD + W+ P   +PERFLDS G F+  S     P+GMG+R CPG  + +   FL    L   ++ + S
Sbjct:    1 PGPLPLPLIGNLHLLSSKPHLDLARLGNIYGPIY----TLNMGSQLAVVLNSYEIAKEAL-MKRGNAFAGRPHHFVGSKFSRGGKGVGFQNYTPTLRRQQKTIMKTVKYFETLKTG--ENLQEIITNEVDYLCDLFV---SHGCQDFDPRRDMTFAAGNVVGRITFGERFTVENEEFWQLMDSLKIFVEGLTATSFIDAFPLLRYFPFSLVKRVQTAVKLRDDVLNKRFREHQDRLRGDGMVLAKSKDLTYALIEEANQKTSRTDSQSDTLI-LTDDHVMMTMNDTIMAGSETPTMLLLWNIYFFVKYPDVQARAFKQIDKVISPDQPIT--WEDRKRLPYLEAFIAEVMRIISIMPLAVPHLAMVDMVLAGYHISKGTTVIVNLWAMGHDPKVWDAPMEFRPERFLDSRGGFSTASSEGFTPYGMGLRSCPGEQLARMELFLFTVRLLRMFEFRAS 444          

Query:  111 PPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLV--TLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDAR---KMGRYRNNPDNIIEYLLQETENSKLVTEKKVNL-NDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKI 1424
            PPGP   PF GN+    G +++K +    K +YG  V      G    V I++ KLA + L  KNG+ +A R S    D +S    ++    Y P WK   R +   +   G     LE  I + ++  CD    +         P   S     N + ++V G+ + L+D ++  +  +   +  +      + ++P+ R+ PL+ ++++ E  T  + L+ + +++ R   K G  R+    + + LL+  E++K      ++L  + H+     D+  A +E       W    +  +P++Q RI  ++  + S  +D  P    +  LPY++A   E  R S +  ++    A K + +GGY IP+   + VN +AI+HD   W +P   +P RFL+ + + +  S ++PFG GVR+C G S+ K   FL +  L   +K+
Sbjct:   29 PPGPPLYPFVGNFPQI-GPVLHKSLTSLGK-QYGRGVFQVQLLGKR-FVIIDNIKLARQVLLKKNGRDVADRTSAYVIDAISRNGCSVIFGKYSPTWKLQRRVVHSALRMYGSGVRILEALILQEVDNLCDIFANSQGAPVDTKLPLTLSVM---NVICALVFGKRYGLDDAEFTDIVATTESMAKLASPENPLIYMPWLRFFPLQVVKKMKETVTARDRLIQRKITEHRETYKEGEIRD----LTDALLKSLEDAKQEDNNAMSLLTEDHLLIAINDVFMAGFETTTTALRWIFLYVAAYPEVQARIHQELDDVISFGRD--PLIADRKSLPYLEATILEVLRISPVFPLIR-RKARKQLNIGGYCIPEETFVYVNLWAIHHDEAEWVDPYKFRPSRFLEGTNSASAYS-MLPFGAGVRVCVGESLAKMELFLFVSRLLHRFKL 459          

Query:   87 KFIERLRLPPGPWALPFWGNYRGFNGAM--IYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLT---PSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIIL----QDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVS---DARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDV-HIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDP-------ENAVLFRFP 1496
            ++ E   LPPGP   P  GN     G+   ++ ++ E  K  YG++ TL+      V +   K A E L  +    +AGR    T D V+    NI  +++ P +      LK  +++  +    P +E  +   +    + L R     G    P      ++ N V S+  G  +TL+D ++++L     DS R +  +      ++  PF  +LP++  + L   +  +N    K V    D+      R+  D  I+ L +  +    V E    +N + HI  +  D++    E    T  W +A L ++P++Q R+   +  +  + K++    + ++ LPY++AV  E  R S+ V +   H A    T+ GY IPK   +  N + ++ D   W +P    P RFLD  G F     ++PFG G R+CPG  I K   FL+   L  +         EFT  +D P       + + L++ P
Sbjct:   21 RYTEPSNLPPGPRPYPLIGNTPLLIGSFSSLHVKLTELAK-IYGSVYTLYLNGQRSVIVCSAKAAREGLVERKDA-IAGRPYSFTLDYVTNGSKNITFSDFCPTF-----LLKKRIAQSSMRRYYPQVEDKVNNQLE---EVLARIKALDGTAFDPHHLLSLVTLNLVTSMTFGTNYTLDDPEFLLLVQMIDDSTRSIGSM----STLDMFPFLMHLPIRTSKLLKSITKTVNEYFMKQVQRHIDSNDGKSIRDLTDGYIKGLTEAEKEDASVHE----VNSIEHIAMVMADMIVPGSETSSTTMGWMIAYLAVYPEVQARLHQQLDDVIGRDKNTVITLKDRDRLPYVEAVIAETMRISTAVPLAIPHKATCDTTINGYFIPKDTTVIFNLWGVHLDPTEWADPHVFNPARFLDEDGKFIKSEKLLPFGAGRRVCPGEKIAKMQLFLMTSRLLRHL--------EFTPPLDGPPPSLQGMKGSALYKLP 484          

Query:  207 YGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPD-NSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSD---ARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDI--MPFGMGVRMCPGTSITKGYGFLLLCNLCLNYK 1421
            YG +  L  G+  IV +N  + A EAL  +     AGR  + T  ++S    +I   ++GPLWK+     K+  S   +  S  K +++ I    DELI+      G+   P D+      N + S V G  + ++D ++  + D   Q       +  V++ P+ R+LP K +R++ E     + +L K   +     + G  R+  D ++       E S  +      + + HI     DI  A  E    + +W +  L  +P++QE++   I ++  +  D  P+   +  LP I+A   E  R SS+V +L  H       L GY +PK  ++  N + ++HD +RW NP+   P RFLD  G F   + +  +PF  G R+C   S+ K   FL +  L   ++
Sbjct:   19 YGEVFRLKVGSHRIVVVNSIEAAREAL-VRRANDFAGRPMLYTASLISRNGTDIAFGDFGPLWKQQ---RKIAHSALRMFGSGLKPLEEKITVEADELIKRLSLVEGRAHNPKDDVNLAVLNIICSFVFGSRYDMDDPEFHTVVDYTEQFVQGFRAASLVDYFPWLRHLPNKGLRQIKEACQNRDVVLQKKYQEHLVTYEHGVIRDLTDALLSANKASQEESAYLP-----MTEDHIIMTMNDIFSAGLETTATSILWSLVYLIRNPKVQEQLHQQIDEVVGR--DRAPELSDRENLPLIEATIAEVLRSSSLVPLLFPHSTTTDTHLRGYEVPKDTIVLFNVWNMHHDPQRWSNPDEFDPTRFLDDKGKFICPATLSYLPFSAGRRVCLAESLGKMQLFLFISRLLHKFR 418          

Query:  207 YGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVS-----KCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLV-----TEKKVN---------LNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTP-KFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD--IMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWS 1433
            YG + TL  G+   V +N Y +A EAL  K G   AGR         S +   +   NY P  +   + +   V      K G   SL++ I K +++ C  L+   D S     P  E  + + N V  I  G  +   ++++  L +S     + +  + F++  PF +Y+P   ++R+ E++ KL +     ++D     ++R++  N+    +  T N  L         K N         L   H+     D++ A  E   MT +W +  L  +P +Q R +  +  +    ++  P  +E +  LPY++A   E  R + ++ +   H A+    L GYHIPKG  + VN +A+ HD + W+ P   +PERFLDS G F+  S     P+GMG+R CPG  + +   FL    L   ++ + S
Sbjct:   60 YGPIYTLNMGSQLAVVLNSYDIAKEAL-MKRGNAFAGRPHHFVGSKFSRDGKGVGFQNYTPTLRRQQKTIMKTVKFFDTLKTG--ESLQEIITKEVDYLCKRLLIFGDQSFD---PRHEVTFAAGNVVGRITFGERYKGGNKEFWQLMESLTIFVEGLTATSFIDAFPFLKYVPFSMVKRV-EKAVKLRD---DVLND-----KFRDHLKNLQNSTISTTTNRDLTYALIDEANKTNCFANSQSDALTIDHVIMTMNDMIMAGSETPTMTLLWILYFLVKYPDVQVRAQEQVDDVS---RNVQPLAWEGRKRLPYLEAFIAEVLRITGVMPLAIQHLAMADTALAGYHIPKGTTVIVNLWAMGHDPKVWDAPMEFRPERFLDSRGGFSTASTEGFTPYGMGLRSCPGEQLARMELFLFTVRLLRMFEFRAS 472          

Query:  108 LPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPK--YGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTP-SLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDK--SEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETE-NSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSE 1439
             PPGP +LP  GN    N   +   +V++ K K  YGN+ + F G+ P V +N  +   EA+  K        + +   D+   +R  +   +YG +W++  R   + +   GL   S+E+ I + I F   +L    +N GK + P    +  + N +  ++    +  ED     +     ++  I +   +   +  P+ R  PL   +        LN  LAK + +  KM R    P + ++  L E E N K  +E+++      +R  F D+  A  +    T +     L ++P IQE+ + +I ++  +K   +  FE ++++PY+QAV +E  RF++IV +  FHC  K   L GY IPKG LI  N  ++  +  +W+ P    PE FL+  G F      MPF  G RMC G  + +   F+++  L   +K  W  +
Sbjct:   27 FPPGPLSLPVLGNLLHLN---LKNPLVDFEKMKESYGNVYSFFIGSRPAVVVNGLQAMKEAIMIKATDFSGRPQDMFVSDLT--QRKGVILVDYGSVWRDHRRFALMTLRNFGLGKISMEERIHEEIQFTISKL---EENIGKTLSPKFMFHNAASNIICKVLFNTRYDYEDGKISEIVQGFVEMLQIANGPWAMMYDAFPWIRSFPLPFNKAFRNMENFLN--LAKRLVNEHKMSRVAGEPRDFVDSYLDELEKNKKDFSEQQL------LRMTF-DLYIAGTDTTSNTMLAGFLYLMVYPHIQEKCQREIDQMLERKDRVS--FEDRHKMPYMQAVIHEVQRFANIVPLSVFHCTTKDSELSGYTIPKGTLIIQNMVSVLREEGQWKFPHEFNPENFLNDQGEFIKPEAFMPFSAGPRMCLGEGLARMELFIIMVTLLRKFKFTWPED 457          

Query:  129 LPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGL-TPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENS-KLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITK 1376
            LP  G+     G +    +      +YG+L  LF G    V +N ++ A E L  + G+  AGR S+ T ++++    +I  ++Y PLWK   R +    +  G  T  L+  +  +++  C EL+    N  +G  P         N V ++V   T+   D +   +      + + + +   V+  P+ +  P   +R+L E     + LL + + +  K      +P ++++ LL+  +   K    +   + D H+     +   A  E    T +W +A L  HP++Q+R++ ++ +  +   D       +  LPY+  V  E  R   +  +L  H A+   ++GG+ + +G  + VN ++I+HD + W+ P+  +PERFLD  G     S  MPFG G R+C G S+ +
Sbjct:   56 LPILGSLPWLGGGLPPHLLFTKLAHRYGSLFGLFLGPHYTVVVNSHQHAKEVLLQR-GRDFAGRPSMVTTELLTRGGKDIAFSDYSPLWKLHRRLVHNSFTLFGEGTSRLQDVVFSAVDSLCSELM---SNGSRGFDPSAAVTRAVTNVVCTLVFSSTYRHGDAELQEVISYNNGIVETIARGGLVDIYPWMKVFPNSSLRKLKECIAVRDRLLTRKLEE-HKASLAEGDPSDLLDALLKGKKGGPKSHGLEGEGITDDHVLMTAAEAFGAGVETTSTTLLWILAYLLHHPEVQQRVQKELDE--NVGADRAANLSDRGHLPYLDCVINEGMRIRPVSPVLIPHTAMTDSSIGGHAVRRGTRVLVNMWSIHHDPQNWDKPDLFQPERFLDDQGNRATPSCFMPFGAGPRVCVGESLAR 466          

Query:   72 VFVILKFIER-----LRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWK-------EMIRALK-LGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRY-RNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLC 1400
            V+++LK   +     LR  PGP  LP  GN     G+  Y  + E  K ++G++  +  G  P+V ++  +   +AL  K G   +GR  + +   +++ +   F  +   +W+         +R+   L  S    +  LE++I K       E+ +     GK    FD   ++     N +  +  GR +   D++ + L +       +       ++IP  RYLP K +++  E + +    + K V++      Y ++N  +I + L+   E+ KL     + ++D  +  I  D+  A ++ I     W +  L  +P I++R+  +I +     ++  P    ++ LP  +A   E FR SS +     HC  +  +L GY+IPK   + +NQ+ INHD + W++P +  P+RFL   G+  +R D   +M FG+G R C G  I +   FL L 
Sbjct:   27 VYLLLKHFNKEIPGGLRQLPGPTPLPIIGNLLEL-GSKPYLSLTEMSK-RFGDVFQIQIGMRPVVVLSGNETVRQAL-IKQGDDFSGRPDLYSFQFINDGKSLAFSTDQAGVWRARRKLAYSALRSFSSLEGSNAEYSCMLEEHICKETEHLVKEIEKVMKTEGK----FDPYRYIVVSVANVICGMCFGRRYDHHDQELVGLVNLSEDFVQVTGSGNPADFIPALRYLPSKAMKKFVEINNRFQCFVQKIVNE--HYATYDKDNIRDITDSLIDHCEDRKLDENSNIQMSDEKVVGIVNDLFGAGFDTISTALSWAVGYLVAYPDIEKRLFEEIKENIGLNRN--PTISDRSNLPLTEAFILEIFRHSSFLPFTIPHCTTRDTSLNGYYIPKDTCVFINQWQINHDPKLWQDPSSFNPDRFLSEDGSEVNRLDGEKVMVFGLGKRRCIGEVIARNEVFLFLA 478          

Query:  102 LRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWK-------EMIRALK-LGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLS---DNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRY-RNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD---IMPFGMGVRMCPGTSITKGYGFLLLC 1400
            LR  PGP  LP  GN     G+  Y  + E  K ++G++  +  G  P+V ++  +   +AL  K G   +GR  + +   +++ +   F  +   +W+         +R+   L  S    +  LE++I K       E+ +     GK    FD   ++     N +  +  GR +   D++ + L +       +       ++IP  RYLP K +++  E + +    + K V++      Y ++N  +I + L+   E+ KL     + ++D  +  I  D+  A ++ I     W +  L  +P I++R+  +I +     ++  P    ++ LP  +A   E FR SS +     HC  +  +L GY+IPK   + +NQ+ INHD + W++P +  P+RFL   G+  +R D   +M FG+G R C G  I +   FL L 
Sbjct:   14 LRQLPGPTPLPIIGNLLEL-GSKPYLSLTEMSK-RFGDVFQIQIGMRPVVVLSGNETVRQAL-IKQGDDFSGRPDLYSFQFINDGKSLAFSTDQAGVWRARRKLAYSALRSFSSLEGSNAEYSCMLEEHICKETEHLVKEIEKVMKTEGK----FDPYRYIVVSVANVICGMCFGRRYDHHDQELVGLVNLSEDFVQVTGSGNPADFIPALRYLPSKAMKKFVEINNRFQCFVQKIVNE--HYATYDKDNIRDITDSLIDHCEDRKLDENSNIQMSDEKVVGIVNDLFGAGFDTISTALSWAVGYLVAYPDIEKRLFEEIKENIGLNRN--PTISDRSNLPLTEAFILEIFRHSSFLPFTIPHCTTRDTSLNGYYIPKDTCVFINQWQINHDPKLWQDPSSFNPDRFLSEDGSEVNRLDGEKVMVFGLGKRRCIGEVIARNEVFLFLA 450          

Query:  198 KPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLW-------KEMIRALKLGVSK-CGLTPSLEKNIQKSINFYCDELIRN-----------PDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRY-RNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDR--SDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIK 1427
            + K+G++  L  G+ P+V ++ Y    +AL  + G+  AGR  + T   V++     F   +GP W       K  +R+      +  G T  LE+++         E+IR             D + KGV P         N V ++  G+ +   D++++ + +   +V  +       ++ P  RY P   ++ L +   ++N  + + + +   M  + +N   +I + L+   E+ +   E  + L+D  I     DI  A ++ I     W +  L   P +Q RI  +I +     +   P F  K+++P+ +A  YE FR ++ V     HC  +  TL GY IPK   + +NQY +NHD + W +PE   P+RFL  SG         ++ FGMG R C G    +   F+ L  L    +I+
Sbjct:   86 RAKHGDVFKLRLGSLPVVVLSGYNTIRQAL-VRQGEDFAGRPELFTFSAVADGTSMTFSEKFGPAWLLHKKLCKNALRSFSQAAPRGSGATCLLEEHVCAEAAEML-EMIREQSAKVELDSEMTDGASKGVDPVKPLVTSVANVVCALCFGKRYDHNDKEFLTIVNINNEVLKLFAAGNLADFFPVFRYFPSLSLKELVQYIRRMNGFMERRIEE--HMHTFDKNYIRDITDALIALCEDREKSKEMSL-LSDTQIIHSVIDIFGAGFDTIIAGLQWSLLYLIKFPDVQRRIHQEIDEHIGSAR--MPNFSDKSKMPFTEAFIYEVFRHAAYVPFTIPHCTTRHTTLNGYFIPKDTCVFINQYQVNHDKDLWGDPEQFCPDRFLGHSGQLNKELTEKVLIFGMGKRRCLGDGFARLEMFVFLATLLHGLRIE 510          

Query:  168 MIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV 1526
            MIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD+MPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV
Sbjct:    1 MIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDLMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV 453          

Query:  183 MVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV 1526
            MVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSD+MPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV
Sbjct:    1 MVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAFTDRSDLMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFRFPKDYLLNISKV 448          

Query:   93 IERLRLPPGPWALPFWGNYRGFNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIFGNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDESYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKK---VNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSG-AFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFR 1490
            I   +LPPGP       ++   N  +IY+++V+ Y PKYG + TL+   TP+VFIND +   E    K  K ++GR +   E I+S  R+NI  ++YGPLWK + R L  G+  C     L + + K  + + + +     +   G+   ++ +W++DN +  ++    F   D DY   Q +   +    ++ +F N  P  +    K + +L +   +L  +L   + + RK G Y+    +I +++L   E   L  + K   + L D+H++    D++FAS EG+G + +W   LL L+P IQE IR +I K      +      WK+++PY  AV  E  R++S     DFH  +  + +G Y IPK  LI +N YAI+HD ++W+NP+ I P+ FL   G +F  R D +P+G+G+R C G + ++   F+L+  +  NYK+ W  +N+  E++DD +NAV  R
Sbjct:    5 ISSYKLPPGPNRNSDEADFI-INEKLIYQKIVQKYIPKYGPICTLYKDGTPVVFINDIETGYEVFVRKLSKQVSGRSASYGEKILSGNRNNILNSDYGPLWKTLQRNLHKGLRHCANLDRLNEIMYKCFDKFKETVEYRRGSKNGGIEVDNDLFWMADNVITMLLFNEIFN--DVDYKKYQGAIEVIPQYAEECDFPNDKP-SKKSDFKSVEKLQKVFNQLIEVLQIRIDEHRKKGDYKIACFDITDFVLLAVEEYHLDPKSKKLGIKLTDLHVKHSLIDVIFASQEGLGNSFVWVFGLLALYPNIQENIRTEINKF-RDDNNVEVTLHWKSKMPYTNAVLCEIQRYASADTFTDFHSTMDDINIGPYEIPKDSLIVLNLYAIHHDKKQWKNPDIIDPQNFLSEDGRSFKRRKDFVPYGLGLRTCVGNTFSENVLFVLIMLVVDNYKMVW-GKNKSQEIIDD-KNAVFIR 467          

Query:   66 LSVFVILK--FIERLRLPPGPWALPFWGNYRG-FNGAMIYKRMVEYYKPKYGNLVTLFWGNTPIVFINDYKLAIEALGNKNGKHLAGRKSVQTEDIVSEERHNIF-GNNYGPLWKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRNPDNSGKGVFPFDE-SYWLSDNTVLSIVIGRTFTLEDEDYIILQDSRRQVFDIMDKSEFVNWIPFGRYLPLKCI-----RRLFEQSTKLNNLLAKFVSDARKMGRYRNNPDNIIEYLLQETENSKLVTEKKVNL---NDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWK--NELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFLDSSGAF-TDRSDIMPFGMGVRMCPGTSIT-KGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVLFR 1490
            +  ++I K  F ++  LPPGP A P  G+    ++  + YKR++E +K KYG ++         V+++DYKL  +A        LAGR  + + D +S    NIF   +    W E+ + + + + K      + +    +   +   +    +    G F  ++  YW+  N ++ +        ++ +Y   QD+   +  +M K   V  + F    PL C+      ++ E S  L++ + K + + +  G Y+ NP   I+Y ++  +N K   EK   L    D  I  +  DI FA  +  G+   W + LL  HP +Q+ IR ++ K      ++   F +K  ++L Y+ AV  E  R  S+     FH A+  V +G Y IPK  +IA+N Y  ++D + W+NP    P+RF+++ G F + +   MPFG+G R C     T K   F+    +C ++KI WSS+N+  ++ +D EN   FR
Sbjct:   17 IVAYIIYKWHFPKKHNLPPGPKAWPIIGSIPDPYSSPLSYKRLIEDWKEKYGEIILFKRMGMNFVYVSDYKLGYQAFVKDYSNELAGR-PLNSVDRLSVGNENIFFTRSLDAGWTELRKQIMIMLRKVAEPQKMTEISNNAYELFATHIREKKELVSDGGFYVEQLCYWVGHNILVQVFWEDAVEFDNPNY---QDTISVIGKLMAK---VGNLAFFDITPLNCLPHPGKNKILEYSKYLSDKVQKHIKERKSDGNYKVNPKYFIDYCIEIQDNQKEQKEKYGQLPMLTDWFISNLSLDIYFAGMDAFGIGFSWTIGLLATHPHVQDNIRKELQK---NDIENVESFNYKMMDKLHYLNAVVNEVMRIHSLSSFTSFHRAMSDVKVGEYDIPKDTIIALNIYGAHYDPKYWKNPNEFNPDRFINADGKFQSPKEGFMPFGVGRRTCVAERYTVKESHFIFTGRICQDFKITWSSKNKTDKVEEDLENT-FFR 497          

Query:  393 WKEMIRALKLGVSKCGLTPSLEKNIQKSINFYCDELIRN-PDNSGKGVFPFDESYWLSDNTVLS-IVIGRTFTLEDEDYIILQD---SRRQVFDIMDKSEFVNWIPFGRYLPLKCIRRLF-----EQSTKL-NNLLAKFVSDARKMGRYRNNPDNIIEYLLQET----ENSKLVTEKKVNLNDVHIRQIFKDILFASYEGIGMTNIWYMALLGLHPQIQERIRLDITKLCSKKKDSTPKFEWKNELPYIQAVEYEFFRFSSIVGILDFHCALKSVTLGGYHIPKGCLIAVNQYAINHDAERWENPETIKPERFL----DSSGAFTDRSDIMPFGMGVRMCPGTSITKGYGFLLLCNLCLNYKIKWSSENEFTELVDDPENAVL 1484
            W  + R+L L V K  +  S E+ + + +N  C  L+++  D  GK +    E +  S   +LS I+I   F  E ++Y IL +      Q+ +++ K+  +   P+   LP K +R LF     +++ K+ N+   + + + ++     N  +N+I+  L+E     EN++++      + D  + +   ++   ++E I     W M L+  H +IQERI  +I +L  +  D  P    K  LPY QAV  E FR+SS+V I   H   + + L  Y I K  L+ VN YA++ D + WE P+   PE FL    +    +T R ++MPFG+G   C G   TK   F++L ++  N+KIK+       E+ ++  N++L
Sbjct:   51 WWTIRRSLILKVLKNFI--SKEQKLIEIVNEECLILLKDIKDVCGKEINT-KELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLL--FPWLEKLP-KFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIID----GITDWQLIRNGIELFIVAFEKIRTLLSWSMVLMARHSEIQERIHEEIIQLIGR--DKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRR-----EITEENSNSIL 416