Cilia- and flagella-associated protein 73

Overview
NameCilia- and flagella-associated protein 73
Smed IDSMED30030217
Length (bp)1189
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cilia- and flagella-associated protein 73 (SMED30030217) t-SNE clustered cells

Violin plots show distribution of expression levels for Cilia- and flagella-associated protein 73 (SMED30030217) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cilia- and flagella-associated protein 73 (SMED30030217) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cilia- and flagella-associated protein 73 (SMED30030217) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030217

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30030217SMESG000073880.1 Contig33509newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30030217SMESG000073880.1 Contig33509uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Human
Match: CCDC42 (coiled-coil domain containing 42 [Source:HGNC Symbol;Acc:HGNC:26528])

HSP 1 Score: 119.783 bits (299), Expect = 2.772e-30
Identity = 101/283 (35.69%), Postives = 155/283 (54.77%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEK---------YRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFED 903
            L K+P  E  S + +  LLEK++E   + +    +K+ F+ +ME+   R  +L  KE QL   + +  +F++EN+ K+ RA++KA  ERE    K + + ELTK      +KQE + L+LE          Y  +  Y+E V+E SE F EI EVI R+ TL S   DL++  +  Q ++   K  L +  E ++ +I+Q NN   +LQ+  DR +S  +   + W  + ++AA+KTL  G IKMAT NL+ I  K   K++    L D  KQLD IQ F +D
Sbjct:   27 LQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKEREL---KCQHMQELTK------RKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMRHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQQNNELARLQMRFDRARSNVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHL-KEVTEVALEDTHKQLDMIQQFIQD 298
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Human
Match: CFAP73 (cilia and flagella associated protein 73 [Source:HGNC Symbol;Acc:HGNC:37100])

HSP 1 Score: 108.227 bits (269), Expect = 5.176e-26
Identity = 86/276 (31.16%), Postives = 156/276 (56.52%), Query Frame = 1 
Query:   88 KIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 915
            K+PE+  D +    RLLEKR+E+ + D+A Q QKE F+ K  + +QR   LE+KE +L  S +RF+KFL+++E+++NRA+++A  ER     +  E L L   L + +++   L+ +L++       +E  +E+   F E+ E++ RF  L  T   L  R+R    +L   +  L QL++    +++    R+ QLQ  L+  +  TL+  ++W  + ++AA+KTL  G+ +MA  NL+ +  +  G+   +  + D   QL+ ++ F +DL+ +
Sbjct:   20 KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQP-PTLDIEDTEGQLEHVKLFMQDLSAM 294
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Human
Match: CCDC42 (coiled-coil domain containing 42 [Source:HGNC Symbol;Acc:HGNC:26528])

HSP 1 Score: 48.9062 bits (115), Expect = 4.797e-6
Identity = 27/58 (46.55%), Postives = 35/58 (60.34%), Query Frame = 1 
Query:  730 WNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFED 903
            W  + ++AA+KTL  G IKMAT NL+ I  K   K++    L D  KQLD IQ F +D
Sbjct:  168 WAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHL-KEVTEVALEDTHKQLDMIQQFIQD 224
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Zebrafish
Match: cfap73 (cilia and flagella associated protein 73 [Source:ZFIN;Acc:ZDB-GENE-060526-194])

HSP 1 Score: 94.7449 bits (234), Expect = 1.450e-21
Identity = 87/261 (33.33%), Postives = 146/261 (55.94%), Query Frame = 1 
Query:  109 DSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEE----KHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLD 879
            D  T A +LLE R +   +  A + QKEE +MK ES ++R+ +++K+E +L  SLL++NKFL+EN++++ RAI+KA  ER   R K  EI +L         ++E L  ++ K + YQ ++E   +MS +F    +VIDR   L+S  ++LLE    NQ  L +E    K  LMQ    +   ++ YNN+  QLQ +LD ++    +   +     ++AA++TL + ++K    N+Y +    + +++ S    D  KQL+
Sbjct:   31 DMKTTAMQLLEAREQSACVSRALEVQKEEMQMKQESLKEREENIKKEEEKLKNSLLQYNKFLQENDARRLRAIKKAEAERAQTRLKELEIQKLKTENDVLLARKELLEERVGKAKCYQEFLERAAKMSRKFENPCQVIDRIQALQSINKELLE----NQTVLEKERERTKLELMQYINKQRTALLHYNNQLHQLQTQLDNIRIEAYKWEIKLKHFQTTAAKETLEFAQLKTTVRNIYQMIITHYIRRV-SEHTEDTFKQLE 286
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Xenopus
Match: klhl13 (kelch like family member 13 [Source:Xenbase;Acc:XB-GENE-923144])

HSP 1 Score: 190.274 bits (482), Expect = 7.549e-57
Identity = 124/280 (44.29%), Postives = 187/280 (66.79%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLV-DILKQLDKIQNFFEDLNYI 915
            L+K+P++E+D LT ATRLLEKRREM E+++A   QKEEF+MK ES QQR+ +LE KE +L +SL +F+KFLKEN+SK+ RA+ KA  ER+   +K +E L L        +++ TL  + EK   YQ Y++ V+E ++EF E++E+IDRF+TL +T   LL+RD  NQ     EK  L+  +E    QI++ NN+  QLQ EL+R++++  +  + W  + ++AA+ TL  G+I+M+T NL+  IS++    ++K+   V D   QL+KIQ  FEDL+ I
Sbjct:   18 LVKMPDREDDFLTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRAELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQLAAHKEREALRLQAENTQLMQRKGTLLERQEKNSKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQEETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLFQTISKQM---RLKTEISVEDTEAQLEKIQICFEDLSAI 294
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Xenopus
Match: klhl13 (kelch like family member 13 [Source:Xenbase;Acc:XB-GENE-923144])

HSP 1 Score: 179.104 bits (453), Expect = 7.979e-53
Identity = 109/242 (45.04%), Postives = 165/242 (68.18%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY 807
            L+K+P++E+D LT ATRLLEKRREM E+++A   QKEEF+MK ES QQR+ +LE KE +L +SL +F+KFLKEN+SK+ RA+ KA  ER+   +K +E L L        +++ TL  + EK   YQ Y++ V+E ++EF E++E+IDRF+TL +T   LL+RD  NQ     EK  L+  +E    QI++ NN+  QLQ EL+R++++  +  + W  + ++AA+ TL  G+I+M+T NL+
Sbjct:   18 LVKMPDREDDFLTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRAELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQLAAHKEREALRLQAENTQLMQRKGTLLERQEKNSKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQEETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLF 259
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Xenopus
Match: cfap73 (cilia and flagella associated protein 73 [Source:Xenbase;Acc:XB-GENE-5779653])

HSP 1 Score: 58.151 bits (139), Expect = 7.510e-9
Identity = 47/175 (26.86%), Postives = 90/175 (51.43%), Query Frame = 1 
Query:  409 QKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMA------TNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 915
             KK+   + +++KY  +  Y+E V++ SE+F +I +++ RF TL +    L + ++ +Q   ++  H +    E ++  I+Q +N   +L + L++ +    E    WN L+  AA+K L  G I+ A      T +   +  K FG++       DI++QL+ I+   +DL  I
Sbjct:  106 HKKRTKTKAQVQKYEKFYRYLEKVVKASEKFQDIPDLMSRFHTLVNY---LPQEEQKSQESRSQRSHCM----EEKSDSIVQLSNEIHRLYIRLEKAKKKRRESELRWNQLLKMAARKNLLLGTIQAAVLDICQTTSSQGLGSKSFGEE-------DIVEQLETIREDIKDLTDI 266
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Mouse
Match: Ccdc42 (coiled-coil domain containing 42 [Source:MGI Symbol;Acc:MGI:3045254])

HSP 1 Score: 138.272 bits (347), Expect = 2.696e-37
Identity = 101/279 (36.20%), Postives = 167/279 (59.86%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 915
            L K P  E  S + + +LLEK++E   + EA +++KE F+ +ME+   R  +L  KE QL   + +F +F++EN+ K+ RA++KA  ERE +R + +E+ +  + +   + + + L +KL+ Y  +  Y+E V+E SE F EI EVI R+ TL S + DL++  +  Q ++   K  L +  E ++ +I+Q+NN   +LQ+  DR +S  +   + W  + ++AA+KTL  G IKMAT NL+ I+S++   K+     L D  KQLD IQ F +DL+ I
Sbjct:   27 LQKFPNVEEQSDSPSIQLLEKKKEAKIMQEAMEHKKEAFQRRMETLNLRWEELGIKEEQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRLRLRELAKAKQEMMALRLEHQKLSVKLQDYAIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQHNNELARLQMRFDRARSDVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKQL--KESTQVSLEDTHKQLDMIQQFIQDLSDI 302
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Mouse
Match: Ccdc42 (coiled-coil domain containing 42 [Source:MGI Symbol;Acc:MGI:3045254])

HSP 1 Score: 88.5817 bits (218), Expect = 1.920e-20
Identity = 54/141 (38.30%), Postives = 84/141 (59.57%), Query Frame = 1 
Query:  496 EFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 915
            +F EI EVI R+ TL S + DL++  +  Q ++   K  L +  E ++ +I+Q+NN   +LQ+  DR +S  +   + W  + ++AA+KTL  G IKMAT NL+ I+S++   K+     L D  KQLD IQ F +DL+ I
Sbjct:   17 QFEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQHNNELARLQMRFDRARSDVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKQL--KESTQVSLEDTHKQLDMIQQFIQDLSDI 155
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Mouse
Match: Cfap73 (cilia and flagella associated protein 73 [Source:MGI Symbol;Acc:MGI:3779542])

HSP 1 Score: 83.5741 bits (205), Expect = 1.394e-17
Identity = 73/271 (26.94%), Postives = 151/271 (55.72%), Query Frame = 1 
Query:   97 EKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLN 909
            E+  D  +V   +LEK+ E+   D   Q QK+E++  +ES  QR  +LE+K  +L  S++ ++KFLKE E++  RA +KAI ER+   N   E+  L   L + + ++  L+ K+++       ++  +E    F E+ +++ RF TL ST   L   ++   +++   +  L+ L+  +  +++  N ++ QL  +L+  +    +  ++W  +++SA++KTL  G+ +MA  NLY + +   G++ ++  + D+  QL++++ F  +++
Sbjct:   23 EQTGDDSSVLQLILEKKEELAVADLGLQAQKKEYRSTIESVNQRWRELEQKGQELQGSVISYDKFLKEVEAR--RAARKAIEERKITGNLDAELRRLRTQLKELRLQRARLQRKVQRLEPCARILKRALEKRPVFEEVSDLVARFETLVSTKAALKLEEQKRLVEMESTRAQLLSLQSEKQDEMLNLNQQRTQLVEQLEAAREHRQQWESKWTEILNSASEKTLLLGRARMAVLNLYHLVRLQQGRR-QTLDVRDVEGQLEEVKRFIMNIS 290
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Mouse
Match: Ccdc42 (coiled-coil domain containing 42 [Source:MGI Symbol;Acc:MGI:3045254])

HSP 1 Score: 60.077 bits (144), Expect = 7.434e-10
Identity = 48/139 (34.53%), Postives = 85/139 (61.15%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEE 498
            L K P  E  S + + +LLEK++E   + EA +++KE F+ +ME+   R  +L  KE QL   + +F +F++EN+ K+ RA++KA  ERE +R + +E+ +  + +   + + + L +KL+ Y  +  Y+E V+E SEE
Sbjct:   23 LQKFPNVEEQSDSPSIQLLEKKKEAKIMQEAMEHKKEAFQRRMETLNLRWEELGIKEEQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRLRLRELAKAKQEMMALRLEHQKLSVKLQDYAIFNKYLEKVVENSEE 161

HSP 2 Score: 48.9062 bits (115), Expect = 4.164e-6
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 1 
Query:  730 WNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 915
            W  + ++AA+KTL  G IKMAT NL+ I+S++   K+     L D  KQLD IQ F +DL+ I
Sbjct:  164 WAHIQNTAAKKTLLLGTIKMATLNLFQIVSKQL--KESTQVSLEDTHKQLDMIQQFIQDLSDI 224
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. UniProt/SwissProt
Match: sp|A7S8T5|CCD42_NEMVE (Coiled-coil domain-containing protein 42 homolog OS=Nematostella vectensis OX=45351 GN=v1g187067 PE=3 SV=1)

HSP 1 Score: 230.335 bits (586), Expect = 1.100e-71
Identity = 137/280 (48.93%), Postives = 201/280 (71.79%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDIL-KQLDKIQNFFEDLNYIA 918
            L+K+PE+E+D LT ATRLLEKRREM E+++A   QKEEF+MKMES QQR+ +LE+KE QL ESLL+F+KFLKEN+SK+ RA++KA  ER+ +R K  EI  L +      K ++ ++ +LEKY  YQ Y+E V+E +EEF EIRE+I R+ TL +T++DLLER+  NQ +  +EK  L++  E +N +I+ YNN+   LQ +L++ QS+ ++  ++W  + ++AA+KTL  G+IKMAT+NL+++  +  G+    T +VD+  KQLDKIQ F +DL  I 
Sbjct:   18 LVKMPEREDDHLTPATRLLEKRREMSEVEQALGAQKEEFQMKMESLQQRREELERKEYQLRESLLKFDKFLKENDSKRARALKKAQEERDMRRAKDCEIARLKEDTSGLMKGRDKVQHRLEKYIIYQQYLEKVLENAEEFQEIREIIARYDTLTATHQDLLERELKNQEKYEKEKARLIKFTEEKNNEILNYNNQLANLQTKLEKTQSVAVKWESQWTHIKNTAAKKTLLLGRIKMATHNLFMLVNRHLGQ----TGMVDMTDKQLDKIQVFIQDLTQIT 293
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. UniProt/SwissProt
Match: sp|B0BMJ2|CC42M_XENTR (Coiled-coil domain-containing protein 42 like-2 OS=Xenopus tropicalis OX=8364 GN=TNeu058c09.1 PE=2 SV=2)

HSP 1 Score: 190.274 bits (482), Expect = 3.999e-56
Identity = 124/280 (44.29%), Postives = 187/280 (66.79%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLV-DILKQLDKIQNFFEDLNYI 915
            L+K+P++E+D LT ATRLLEKRREM E+++A   QKEEF+MK ES QQR+ +LE KE +L +SL +F+KFLKEN+SK+ RA+ KA  ER+   +K +E L L        +++ TL  + EK   YQ Y++ V+E ++EF E++E+IDRF+TL +T   LL+RD  NQ     EK  L+  +E    QI++ NN+  QLQ EL+R++++  +  + W  + ++AA+ TL  G+I+M+T NL+  IS++    ++K+   V D   QL+KIQ  FEDL+ I
Sbjct:   18 LVKMPDREDDFLTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRAELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQLAAHKEREALRLQAENTQLMQRKGTLLERQEKNSKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQEETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLFQTISKQM---RLKTEISVEDTEAQLEKIQICFEDLSAI 294
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. UniProt/SwissProt
Match: sp|Q6NTM6|CC42M_XENLA (Coiled-coil domain-containing protein 42 like-2 OS=Xenopus laevis OX=8355 PE=2 SV=2)

HSP 1 Score: 185.267 bits (469), Expect = 3.433e-54
Identity = 121/283 (42.76%), Postives = 182/283 (64.31%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPL 927
            L+K+P++E+D +T ATRLLEKRREM E+++A   QKEEF+MK ES QQR+ +LE KE +L +SL +F+KFLKEN+SK+ RA+ KA  ER+    K ++ L L        +++  L  + EK   YQ Y++ V+E ++EF E++E+IDRF+TL +T   LL+R+  NQ     EK  L+  +E    QI++ NN+  QLQ EL+R +++  +  + W  + ++AA+ TL  G+++MAT NL+  IS++   K   S +  D   QL+KIQ  FEDL  I   L
Sbjct:   18 LVKMPDREDDFMTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRSELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQMAAQKERDALRLQAENTQLMQRKHILLQRQEKNSIYQRYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRELKNQEHAEMEKARLLHYQEETRSQILELNNQIAQLQGELERARAVAFQWESRWAQIQNTAAENTLRLGRVRMATLNLFQTISKQMRLKTDISVE--DTEAQLEKIQICFEDLAAIHKDL 298
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. UniProt/SwissProt
Match: sp|A6QQM8|CCD42_BOVIN (Coiled-coil domain-containing protein 42 OS=Bos taurus OX=9913 GN=CCDC42 PE=2 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 4.045e-38
Identity = 102/279 (36.56%), Postives = 167/279 (59.86%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 915
            L K P  E+ S + + RLLEK++E   +  A + +KE F+ +ME+   R  +L  KE QL   + +F +F++EN+ K+ RA++KA  ERE +R + +E+ +  + +   + + + L  KL++Y  +  Y+E V+E SE F EI EVI R+ TL S + DL++  +  Q ++   K  L + KE ++ +I+Q+NN   +LQ+  DR +S  +   + W  + ++AA+KTL  G IKMAT NL+ I+S++   K+     L D  KQLD IQ F +DL+ I
Sbjct:   27 LQKFPSIEDQSDSPSVRLLEKKKEAKIMHHAMEQKKETFQRRMETLNLRWEELGIKEAQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRQRMRELAKAKQEMAVLRLEHQRLSAKLQEYSIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYKEEKDDEILQHNNELARLQMRFDRARSDVIIWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKQL--KEATFVSLEDTHKQLDMIQQFIQDLSDI 302
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. UniProt/SwissProt
Match: sp|Q5SV66|CCD42_MOUSE (Coiled-coil domain-containing protein 42 OS=Mus musculus OX=10090 GN=Ccdc42 PE=2 SV=2)

HSP 1 Score: 138.272 bits (347), Expect = 1.886e-36
Identity = 101/279 (36.20%), Postives = 167/279 (59.86%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLY-IISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 915
            L K P  E  S + + +LLEK++E   + EA +++KE F+ +ME+   R  +L  KE QL   + +F +F++EN+ K+ RA++KA  ERE +R + +E+ +  + +   + + + L +KL+ Y  +  Y+E V+E SE F EI EVI R+ TL S + DL++  +  Q ++   K  L +  E ++ +I+Q+NN   +LQ+  DR +S  +   + W  + ++AA+KTL  G IKMAT NL+ I+S++   K+     L D  KQLD IQ F +DL+ I
Sbjct:   27 LQKFPNVEEQSDSPSIQLLEKKKEAKIMQEAMEHKKEAFQRRMETLNLRWEELGIKEEQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRLRLRELAKAKQEMMALRLEHQKLSVKLQDYAIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQHNNELARLQMRFDRARSDVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKQL--KESTQVSLEDTHKQLDMIQQFIQDLSDI 302
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. TrEMBL
Match: A0A1S3H6L6 (coiled-coil domain-containing protein 42 homolog OS=Lingula unguis OX=7574 GN=LOC106152551 PE=4 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 1.130e-69
Identity = 136/282 (48.23%), Postives = 208/282 (73.76%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPL 927
            L+K+PE+E+D LT ATRLLEKRREM E+++A   QKEEF+MKMES QQR+ +LE+KE QL E+LL+F+KFLKEN+SK++RA++KA  E + ++ K K+I +L +   ++ K++E L+ KLEK+  +Q Y++ V+E SEEFSEIREVI R++TL +T+EDLLERD+ NQ ++ + + +LM+  E+++ +I+ YNNR   LQ  LD+ QS  ++  ++W  + ++AA+KTL  G+IKMAT+NL+++  K   K+ ++    D  +QL+KIQ F +DL  I   +
Sbjct:   18 LVKMPEREDDHLTPATRLLEKRREMAEVEQALAAQKEEFQMKMESLQQRREELERKEFQLKEALLKFDKFLKENDSKRSRAVKKANDEIDLRKQKEKDIDKLREETSEFAKQREKLQTKLEKHVIFQKYLDKVLETSEEFSEIREVIARYATLTATHEDLLERDQANQEKIEKMRQDLMKYTEDKHNEILGYNNRLSSLQTRLDKAQSAAVKWESKWTHIKNTAAKKTLILGQIKMATHNLFMLVNK-HQKQGQTEMTEDTNEQLNKIQTFIQDLTQITTEI 298
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. TrEMBL
Match: A0A2B4SQU4 (Coiled-coil domain-containing protein 42A OS=Stylophora pistillata OX=50429 GN=Ccdc42 PE=4 SV=1)

HSP 1 Score: 228.409 bits (581), Expect = 1.556e-68
Identity = 134/282 (47.52%), Postives = 201/282 (71.28%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPL 927
            L+K+PE+E+D LT ATRLLEKRREM E+++A   QKEEF+MKMES QQR+ +L++KE QL ESLL+F+KFLKEN+SK+ RA++KA  ERE +R K +EI  L +      K+++ ++ KLE+   YQ Y+E V+E +EEF EIREVI R+ TL +T++DLLER+  NQ +  +EK  L++  E +N +I+ YNN+   LQ +L+R QS+ ++  ++W  + ++AA+KTL  G+IKMAT+NL+++  +      ++T +    KQL+KIQ F +DL  I + +
Sbjct:   18 LVKMPEREDDHLTPATRLLEKRREMSEVEQALAAQKEEFQMKMESLQQRREELDRKEYQLKESLLKFDKFLKENDSKRARALKKAAEEREMRRAKDREIARLKEETATLMKERDHIQYKLERNVIYQQYLEKVLESAEEFQEIREVIARYDTLTATHQDLLERETKNQEKYEKEKGRLVKFTEEKNNEILNYNNQLAHLQTQLERAQSVAVKWESQWTHIQNTAAKKTLLLGRIKMATHNLFMLVNRHLK---QNTVIEHTEKQLEKIQVFIQDLTQITSEI 296
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. TrEMBL
Match: A0A3M6URY7 (DUF4200 domain-containing protein OS=Pocillopora damicornis OX=46731 GN=pdam_00019253 PE=4 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 4.977e-66
Identity = 133/282 (47.16%), Postives = 199/282 (70.57%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPL 927
            L+K+PE+E+D LT ATRLLEKRREM E+++A   QKEEF+MKMES QQR+ +L++KE QL ESLL+F+KFLKEN+SK+ RA++KA  ER+ +R K +EI  L +      K+++ ++ KLE+   YQ Y+E V+E +EEF EIREVI R+ TL +T++DLLER+  NQ +  +EK  L++  E +N +I+ YNN     Q +L+R QS+ ++  ++W  + ++AA+KTL  G+IKMAT+NL+++  +      ++T +    KQL+KIQ F +DL  I N +
Sbjct:   18 LVKMPEREDDHLTPATRLLEKRREMSEVEQALAAQKEEFQMKMESLQQRREELDRKEYQLKESLLKFDKFLKENDSKRARALKKAAEERDMRRAKDREIARLKEETATLMKERDHIQYKLERNVIYQQYLEKVLESAEEFQEIREVIARYDTLTATHQDLLERETKNQEKYEKEKGRLVKFTEEKNNEILNYNN-----QTQLERAQSVAVKWESQWTHIQNTAAKKTLLLGRIKMATHNLFMLVNRHLK---QNTVIEHTEKQLEKIQVFIQDLTQITNEI 291
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. TrEMBL
Match: H2Y4L5 (DUF4200 domain-containing protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 218.779 bits (556), Expect = 9.004e-65
Identity = 141/289 (48.79%), Postives = 198/289 (68.51%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEIL-------ELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPL 927
            L+K+PE+E+D LT ATRLLEKRREM E+++A   QKEEF+MKMES QQR+ +LE+KE QL ESLL+F+KFLKEN+SK+ RAI+KA  ERE +R+K K+I         L+K  G YQK       KLEK   +Q Y+E V E ++EFSEIRE+I R+ TL +T+ DL++RD  NQ  + EEK  L++  E +N +I+ YNN+  QLQ  LD+ QS  ++  ++W  + ++AA+KTL  G+IK+AT+NL+ +  K   K+  +  L +   QLDKIQ F +DL+ I   +
Sbjct:   18 LVKMPEREDDHLTPATRLLEKRREMAEVEQALTAQKEEFQMKMESLQQRREELERKEHQLKESLLKFDKFLKENDSKRARAIKKAQDERELRRSKEKDIGRLQDDIERLSKERGRYQK-------KLEKNSIFQKYMERVQESTDEFSEIREIIGRYDTLVATHVDLMKRDLKNQDAIEEEKGRLVKFTEEKNNEILSYNNQLAQLQTRLDQAQSKAVKWESKWTHIQNTAAKKTLLLGRIKIATHNLFQLVNKHL-KQQATVPLENTALQLDKIQMFIQDLSQITTEI 298
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. TrEMBL
Match: A0A2C9K6J4 (DUF4200 domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106053244 PE=4 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 2.241e-63
Identity = 132/282 (46.81%), Postives = 199/282 (70.57%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPL 927
            L+K+PE+E+D LT ATRLLEKRREM E+++A   QKEEF+MKMES QQR+ +LE+KE QL ESLL+F+KFLKEN+SK+ RA++KA  ERE ++ K KEI  + +    YQK++E L+ K+EKY  + +Y++ V+E  E+F EIR++I R+ TL +T++DLLERD+ N  ++ +++ +LM+  E +  Q++ YNN+   LQ  LD  QS  ++  ++W  + ++AA+KTL  G+IKMAT+NLY   Q     + +   + D  +QL +IQ F +DLN I + +
Sbjct:   18 LVKMPEREDDHLTPATRLLEKRREMAEVEQALAAQKEEFQMKMESLQQRREELERKEFQLKESLLKFDKFLKENDSKRARAVKKANDERELKKQKDKEIERVKEETEAYQKQKEMLQKKVEKYVIFHNYMDKVLEAGEDFHEIRDIITRWDTLTATHQDLLERDQLNHEKVEKQRQDLMKYMEEKENQVLNYNNQLSTLQTRLDAAQSEAVKWESKWTHIKNTAAKKTLLLGRIKMATHNLY---QLVRSHQNQLDDVEDTTEQLIQIQLFVQDLNQITSEI 296
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Cavefish
Match: cfap73 (coiled-coil domain-containing protein 42 homolog [Source:NCBI gene;Acc:103032501])

HSP 1 Score: 136.346 bits (342), Expect = 8.640e-37
Identity = 94/269 (34.94%), Postives = 161/269 (59.85%), Query Frame = 1 
Query:   91 IPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFF 897
            +P  E D  T  TR+L+KRRE+  +D+  + QKEEF+ K +S +QR+ +L KKE +L +SLL FNK+LK+N++K+ R ++KA  E+   R + KE+ +L + +     K+E ++ ++ + R Y  ++++V++ S++F +I + I RF TL    E LL+R    + +   E   L +    R+  ++ YNN   QLQ ELD + S  L   + WN + ++AA++TL  G+IK+ T NLY ++ +      +   + D L QLD+++  F
Sbjct:   20 VPMPEEDLRTGTTRILDKRREIKYMDDVLRNQKEEFEAKKKSLEQRRDELRKKEEKLKDSLLNFNKYLKDNDAKQARGLKKAEAEKALVREREKEVQQLQRHIAALLTKKEKMQKRVSQKRIYWSFLDSVLKSSKKFEDIGKFIGRFETLVCMREQLLKRQSTVESEREREAVQLRRYVSERSSALLHYNNTLSQLQTELDTILSQALRWESTWNHIQATAAKETLLLGQIKIVTLNLYHMTGR-VTSGAEGFNVDDTLDQLDRVRKLF 287
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Cavefish
Match: cfap73 (coiled-coil domain-containing protein 42 homolog [Source:NCBI gene;Acc:103032501])

HSP 1 Score: 135.961 bits (341), Expect = 1.324e-36
Identity = 95/270 (35.19%), Postives = 162/270 (60.00%), Query Frame = 1 
Query:   91 IPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFE 900
            +P  E D  T  TR+L+KRRE+  +D+  + QKEEF+ K +S +QR+ +L KKE +L +SLL FNK+LK+N++K+ R ++KA  E+   R + KE+ +L + +     K+E ++ ++ + R Y  ++++V++ S++F +I + I RF TL    E LL+R    + +   E   L +    R+  ++ YNN   QLQ ELD + S  L   + WN + ++AA++TL  G+IK+ T NLY ++ +      +   + D L QLD+IQ + +
Sbjct:   20 VPMPEEDLRTGTTRILDKRREIKYMDDVLRNQKEEFEAKKKSLEQRRDELRKKEEKLKDSLLNFNKYLKDNDAKQARGLKKAEAEKALVREREKEVQQLQRHIAALLTKKEKMQKRVSQKRIYWSFLDSVLKSSKKFEDIGKFIGRFETLVCMREQLLKRQSTVESEREREAVQLRRYVSERSSALLHYNNTLSQLQTELDTILSQALRWESTWNHIQATAAKETLLLGQIKIVTLNLYHMTGRVTS-GAEGFNVDDTLDQLDRIQLYIQ 288
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Cavefish
Match: cfap73 (coiled-coil domain-containing protein 42 homolog [Source:NCBI gene;Acc:103032501])

HSP 1 Score: 103.605 bits (257), Expect = 3.780e-25
Identity = 76/219 (34.70%), Postives = 130/219 (59.36%), Query Frame = 1 
Query:   91 IPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLIS 747
            +P  E D  T  TR+L+KRRE+  +D+  + QKEEF+ K +S +QR+ +L KKE +L +SLL FNK+LK+N++K+ R ++KA  E+   R + KE+ +L + +     K+E ++ ++ + R Y  ++++V++ S++F +I + I RF TL    E LL+R    + +   E   L +    R+  ++ YNN   QLQ ELD +    L ++  W   +S
Sbjct:   20 VPMPEEDLRTGTTRILDKRREIKYMDDVLRNQKEEFEAKKKSLEQRRDELRKKEEKLKDSLLNFNKYLKDNDAKQARGLKKAEAEKALVREREKEVQQLQRHIAALLTKKEKMQKRVSQKRIYWSFLDSVLKSSKKFEDIGKFIGRFETLVCMREQLLKRQSTVESEREREAVQLRRYVSERSSALLHYNNTLSQLQTELDTI----LSQALRWVQPVS 234
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Cavefish
Match: ENSAMXT00000003941.2 (pep primary_assembly:Astyanax_mexicanus-2.0:3:67849880:67853480:-1 gene:ENSAMXG00000003857.2 transcript:ENSAMXT00000003941.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 7.782e-10
Identity = 51/160 (31.87%), Postives = 84/160 (52.50%), Query Frame = 1 
Query:  415 KQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELD--RLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQ 888
            K+E L+ ++ + R Y   +++V++ S+EF +  ++I RF TL  T E LL+R    + +   E   L Q    R   +  Y N   QLQ EL+  R Q+  LE + +   +  + A++TL  G+I +AT NLY ++        +   + D L QLD+IQ
Sbjct:   51 KKEKLQKRVSQDRIYWSLLDSVLKSSDEFEDFGKLIGRFKTLVRTKEQLLKRQSTMESEREREAVQLRQYVSERRSLLQHYENTLSQLQTELNTTRSQARRLESTEK--HIQKTDAKRTLLLGRIHVATRNLYQMTGGVTS-GAEGFNVKDTLDQLDRIQ 207
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Cavefish
Match: si:ch1073-416d2.4 (si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121-564])

HSP 1 Score: 57.3806 bits (137), Expect = 9.391e-9
Identity = 53/197 (26.90%), Postives = 105/197 (53.30%), Query Frame = 1 
Query:  127 TRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSE------IREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRL 699
            T LL+K+ ++ E++   + ++ EF+ +M+  ++R+ +L + + +      +F KF++ENE K+ RA++K  +ER+    K KE  EL +     Q  Q  L+ ++EKY+ Y+ Y+  ++++  E+ E         +I R  TL  T + L++       +L + + NL  LK+  N   +  N    +LQ + D++
Sbjct:   35 TLLLKKQLKVDEVNTELKQKQLEFRARMQILEKRRAELLQTKDRAV----KFEKFVEENEVKRRRALKKYQVERKQNEQKEKEKSELCEHFDQLQIHQ-YLKQRVEKYKMYEEYLRKILDLLPEYLEYGSDSLAMPIIRRHETLSITQQTLVQHLTGLSEELEQGQRNLDSLKQEHNTSKLMINKEMSELQTQWDQI 226
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Nematostella
Match: EDO39885 (Coiled-coil domain-containing protein 42 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7S8T5])

HSP 1 Score: 230.335 bits (586), Expect = 4.508e-73
Identity = 137/280 (48.93%), Postives = 201/280 (71.79%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDIL-KQLDKIQNFFEDLNYIA 918
            L+K+PE+E+D LT ATRLLEKRREM E+++A   QKEEF+MKMES QQR+ +LE+KE QL ESLL+F+KFLKEN+SK+ RA++KA  ER+ +R K  EI  L +      K ++ ++ +LEKY  YQ Y+E V+E +EEF EIRE+I R+ TL +T++DLLER+  NQ +  +EK  L++  E +N +I+ YNN+   LQ +L++ QS+ ++  ++W  + ++AA+KTL  G+IKMAT+NL+++  +  G+    T +VD+  KQLDKIQ F +DL  I 
Sbjct:   18 LVKMPEREDDHLTPATRLLEKRREMSEVEQALGAQKEEFQMKMESLQQRREELERKEYQLRESLLKFDKFLKENDSKRARALKKAQEERDMRRAKDCEIARLKEDTSGLMKGRDKVQHRLEKYIIYQQYLEKVLENAEEFQEIREIIARYDTLTATHQDLLERELKNQEKYEKEKARLIKFTEEKNNEILNYNNQLANLQTKLEKTQSVAVKWESQWTHIKNTAAKKTLLLGRIKMATHNLFMLVNRHLGQ----TGMVDMTDKQLDKIQVFIQDLTQIT 293
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Nematostella
Match: EDO38155 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDR1])

HSP 1 Score: 52.373 bits (124), Expect = 1.333e-7
Identity = 49/169 (28.99%), Postives = 92/169 (54.44%), Query Frame = 1 
Query:  277 RFNKFLKENESKKNRAIQK--AILERENQRNKSKEIL--ELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIE-MSEEFSEIRE-----VIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSI---TLEKSAEWNSLI 744
            +F KF+KENE+K+ RA+QK    L+ ++Q++K +EIL  EL +L    + ++ +L  K+ KY  Y+ Y+  V++ + E++ E  +     ++ RF TL +T   L++   +    + + +  L+ +  N    ++  N+       EL  LQ I   T +K+AE + L+
Sbjct:   48 KFEKFIKENEAKRRRAVQKYQTELKLKDQKSKEEEILAAELQQL----KARKHSLEAKIAKYSVYEKYLLKVLDFLPEDYLEASDSMLMGIMMRFRTLSATNHTLMQMLSDKADGVEQSQQKLLDMNNNHTQHLVLINS-------ELAHLQQILEETSQKNAELDQLL 205
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BLAST of Cilia- and flagella-associated protein 73 vs. Planmine SMEST
Match: SMESG000073880.1 (SMESG000073880.1)

HSP 1 Score: 533.102 bits (1372), Expect = 0.000e+0
Identity = 298/299 (99.67%), Postives = 299/299 (100.00%), Query Frame = 1 
Query:   37 MDMXXXXXXXXXXXXLIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 933
            MDMSKKSFFNFEEKFLIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAA+KTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA
Sbjct:    1 MDMSKKSFFNFEEKFLIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAARKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 299
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BLAST of Cilia- and flagella-associated protein 73 vs. Planmine SMEST
Match: SMESG000073880.1 (SMESG000073880.1)

HSP 1 Score: 531.946 bits (1369), Expect = 0.000e+0
Identity = 283/284 (99.65%), Postives = 284/284 (100.00%), Query Frame = 1 
Query:   82 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 933
            LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAA+KTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA
Sbjct:   14 LIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAARKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 297
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BLAST of Cilia- and flagella-associated protein 73 vs. Planmine SMEST
Match: SMESG000073880.1 (SMESG000073880.1)

HSP 1 Score: 460.685 bits (1184), Expect = 7.549e-163
Identity = 246/248 (99.19%), Postives = 248/248 (100.00%), Query Frame = 1 
Query:  190 EEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 933
            +EFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAA+KTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA
Sbjct:   91 QEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAARKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 338
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Planmine SMEST
Match: SMESG000073880.1 (SMESG000073880.1)

HSP 1 Score: 457.988 bits (1177), Expect = 2.595e-162
Identity = 246/248 (99.19%), Postives = 248/248 (100.00%), Query Frame = 1 
Query:  190 EEFKMKMESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 933
            +EFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAA+KTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA
Sbjct:   54 QEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAARKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 301
[Close]
BLAST of Cilia- and flagella-associated protein 73 vs. Planmine SMEST
Match: SMESG000073880.1 (SMESG000073880.1)

HSP 1 Score: 448.358 bits (1152), Expect = 1.600e-159
Identity = 241/242 (99.59%), Postives = 242/242 (100.00%), Query Frame = 1 
Query:  208 MESFQQRKFDXXXXXXXXXXXXXRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 933
            MESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAA+KTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA
Sbjct:    1 MESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAARKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA 242
The following BLAST results are available for this feature:
BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CCDC422.772e-3035.69coiled-coil domain containing 42 [Source:HGNC Symb... [more]
CFAP735.176e-2631.16cilia and flagella associated protein 73 [Source:H... [more]
CCDC424.797e-646.55coiled-coil domain containing 42 [Source:HGNC Symb... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cfap731.450e-2133.33cilia and flagella associated protein 73 [Source:Z... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
klhl137.549e-5744.29kelch like family member 13 [Source:Xenbase;Acc:XB... [more]
klhl137.979e-5345.04kelch like family member 13 [Source:Xenbase;Acc:XB... [more]
cfap737.510e-926.86cilia and flagella associated protein 73 [Source:X... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Ccdc422.696e-3736.20coiled-coil domain containing 42 [Source:MGI Symbo... [more]
Ccdc421.920e-2038.30coiled-coil domain containing 42 [Source:MGI Symbo... [more]
Cfap731.394e-1726.94cilia and flagella associated protein 73 [Source:M... [more]
Ccdc427.434e-1034.53coiled-coil domain containing 42 [Source:MGI Symbo... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A7S8T5|CCD42_NEMVE1.100e-7148.93Coiled-coil domain-containing protein 42 homolog O... [more]
sp|B0BMJ2|CC42M_XENTR3.999e-5644.29Coiled-coil domain-containing protein 42 like-2 OS... [more]
sp|Q6NTM6|CC42M_XENLA3.433e-5442.76Coiled-coil domain-containing protein 42 like-2 OS... [more]
sp|A6QQM8|CCD42_BOVIN4.045e-3836.56Coiled-coil domain-containing protein 42 OS=Bos ta... [more]
sp|Q5SV66|CCD42_MOUSE1.886e-3636.20Coiled-coil domain-containing protein 42 OS=Mus mu... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3H6L61.130e-6948.23coiled-coil domain-containing protein 42 homolog O... [more]
A0A2B4SQU41.556e-6847.52Coiled-coil domain-containing protein 42A OS=Stylo... [more]
A0A3M6URY74.977e-6647.16DUF4200 domain-containing protein OS=Pocillopora d... [more]
H2Y4L59.004e-6548.79DUF4200 domain-containing protein OS=Ciona savigny... [more]
A0A2C9K6J42.241e-6346.81DUF4200 domain-containing protein OS=Biomphalaria ... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cfap738.640e-3734.94coiled-coil domain-containing protein 42 homolog [... [more]
cfap731.324e-3635.19coiled-coil domain-containing protein 42 homolog [... [more]
cfap733.780e-2534.70coiled-coil domain-containing protein 42 homolog [... [more]
ENSAMXT00000003941.27.782e-1031.88pep primary_assembly:Astyanax_mexicanus-2.0:3:6784... [more]
si:ch1073-416d2.49.391e-926.90si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO398854.508e-7348.93Coiled-coil domain-containing protein 42 homolog ... [more]
EDO381551.333e-728.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cilia- and flagella-associated protein 73 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cilia- and flagella-associated protein 73 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000073880.10.000e+099.67SMESG000073880.1[more]
SMESG000073880.10.000e+099.65SMESG000073880.1[more]
SMESG000073880.17.549e-16399.19SMESG000073880.1[more]
SMESG000073880.12.595e-16299.19SMESG000073880.1[more]
SMESG000073880.11.600e-15999.59SMESG000073880.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030217 ID=SMED30030217|Name=Cilia- and flagella-associated protein 73|organism=Schmidtea mediterranea sexual|type=transcript|length=1189bp
CCGATCTGATTTCCCAATTTTAAAAATCCAAATCCCATGGATATGTCAAA
GAAAAGTTTTTTTAACTTTGAGGAAAAATTTTTAATAAAGATTCCTGAAA
AAGAAAATGATTCTTTAACAGTGGCAACAAGGCTATTGGAAAAAAGACGA
GAAATGCATGAAATCGACGAAGCATTTCAATACCAGAAAGAAGAATTCAA
AATGAAAATGGAGAGTTTTCAACAAAGAAAGTTTGATTTGGAGAAAAAAG
AATTACAATTATCAGAATCACTATTGAGATTTAATAAATTTCTCAAAGAA
AATGAATCAAAGAAAAACCGAGCTATACAGAAAGCAATTTTGGAAAGAGA
AAATCAAAGAAATAAATCCAAGGAGATTTTAGAACTCACAAAATTATTGG
GAGATTATCAGAAAAAGCAAGAAACTTTGAGATTGAAATTAGAAAAATAT
CGGTGGTATCAGCATTATATTGAAAATGTTATTGAAATGTCTGAAGAGTT
TTCTGAAATTAGAGAAGTTATTGATAGATTTTCAACTCTGCGTTCAACAT
ATGAAGATTTGTTGGAAAGAGATAGAAACAATCAAATGCAGCTTAATGAA
GAGAAACATAATCTCATGCAACTAAAAGAGAATAGAAATGGCCAAATTAT
TCAGTATAACAATAGACAAGGGCAGCTACAACTAGAGCTTGACCGTCTCC
AGTCAATAACTCTGGAAAAGTCAGCAGAATGGAATTCACTTATTAGTAGT
GCAGCACAGAAAACTCTAAGTTATGGAAAAATTAAAATGGCAACGAATAA
TTTGTACATTATATCACAAAAGTTTTTTGGAAAAAAAATTAAATCGACAA
AGCTTGTTGATATATTAAAACAATTGGATAAAATTCAAAATTTTTTTGAG
GATTTAAACTATATAGCTAATCCGTTGGAAGCTTAGAATAAAGAAAAGTT
CGAAAACTTTGATCTCAAATATTTGAAAGATAAATTATTTTACAATTTAA
ATTTTTGTGAATATTATTTTTAAAGTTAGAATTTGTAATGTCTGACAATA
TAAAGTCAATGTTACTTTGGAATTAAAATAATGAAATAATAATTTTTGTG
AATTGTTTGATGTTTTATATAATTTGATGATATTATTATGATTTCTTTTA
TTTTTGATCTGAAAATTTCGTATTTTGCAAATTAGCTTG
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protein sequence of SMED30030217-orf-1

>SMED30030217-orf-1 ID=SMED30030217-orf-1|Name=SMED30030217-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=300bp
MDMSKKSFFNFEEKFLIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQ
KEEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKA
ILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIE
MSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENR
NGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAAQKTLSYGKIK
MATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYIANPLEA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0003341cilium movement
GO:0036159inner dynein arm assembly
GO:0048870cell motility
GO:2000574regulation of microtubule motor activity
GO:0007286spermatid development
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0070840dynein complex binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005856cytoskeleton
GO:0005929cilium
GO:0031514motile cilium
GO:0042995cell projection
GO:0097545axonemal outer doublet
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR025252DUF4200
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 185..205
NoneNo IPR availableCOILSCoilCoilcoord: 60..80
NoneNo IPR availablePANTHERPTHR21683UNCHARACTERIZEDcoord: 20..305
NoneNo IPR availablePANTHERPTHR21683:SF2CILIA AND FLAGELLA-ASSOCIATED PROTEIN 73coord: 20..305
IPR025252Domain of unknown function DUF4200PFAMPF13863DUF4200coord: 42..159
e-value: 5.0E-27
score: 94.7