G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview
NameG_PROTEIN_RECEP_F1_2 domain-containing protein
Smed IDSMED30030212
Length (bp)1225
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30030212) t-SNE clustered cells

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30030212) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30030212) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30030212) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030212

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30030212h1SMcG0006038 Contig2266newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030212h1SMcG0006038 Contig2266uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030212h1SMcG0016546 Contig2266newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30030212h1SMcG0016546 Contig2266uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
parapharyngeal regionSMED30030212h1SMcG0006038 SmedASXL_006942SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
muscle cellSMED30030212h1SMcG0006038 dd_Smed_v4_22525_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
enteric muscle cellSMED30030212h1SMcG0006038 dd_Smed_v4_22525_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: dmsr-8 (DroMyoSuppressin Receptor related [Source:UniProtKB/TrEMBL;Acc:Q18475])

HSP 1 Score: 118.242 bits (295), Expect = 5.286e-29
Identity = 95/342 (27.78%), Postives = 160/342 (46.78%), Query Frame = 2 
Query:  143 LTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITT--EKRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITVFKHKYHWFVIKEGFQKEED----------------IQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAAL--AQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            +T  +T Y  IH Y+S ILC+ G   NI+  IVL + +M + +N LL  IAL D++ M S  ++  +  L          +   W  F+  HS   +  H TS  L V+LA  R +++   T+   + + N+ +    V  F +  + ++PN+   +I +      W   K     E+D                I F+  G + K +  ++L                    L   I+ V    K++     ++  N  R P    + +LV V+  F+  ELPQG+++   A+   + F D +YI++GD+MD+L L+NS++NFI+YC MS++FR  F  +F
Sbjct:   20 VTNINTAYAHIHPYVSVILCLAGTAMNIVTVIVLTRPSMRSAVNSLLCAIALCDILVMTSVLVFVTHFLLFAGYRCDPTDYNIYWAYFLYYHSQATVIFHATSIWLTVLLAQIRVFSIRRATSVAGESVTNQMTCIIAVTTFIVVCLLNVPNMLTFEI-IETPASLWLQCKANETAEDDMLVYLVAPSDHCGLLNIAFWTNGVLFKVVPCLLLTFSIVA--------------LVSIIRDVGKRRKQL-----AQVMNKKRMPRDHTTPMLVAVLSIFLFAELPQGVLHVFNAIFTKETFYDKIYIHLGDVMDVLSLLNSAVNFIIYCAMSRKFRAVFIQIF 341
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: dmsr-7 (DroMyoSuppressin Receptor related [Source:UniProtKB/TrEMBL;Acc:O16548])

HSP 1 Score: 78.5666 bits (192), Expect = 1.168e-15
Identity = 47/132 (35.61%), Postives = 71/132 (53.79%), Query Frame = 2 
Query:  104 PNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMIN-PINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTL 496
            PN N ++      L  F  WY+ IHGY+  ++C+ G+ TN ++  VL +  M N  +N +L  +A+ D+  M SY IY ++  L    S C+   T+ W+ F+L H  + I  HTTS  L V +A  R  TL
Sbjct:   12 PNSNSTQA-FLRKLAHFQRWYQPIHGYVCVLICVFGIFTNFVHVAVLSRPNMRNSAVNCILTAVAVCDIGTMASYLIYIIHFVLRRNNS-CTPTFTHSWLQFLLWHVVLSITLHTTSLWLAVAMAFIRRMTL 141

HSP 2 Score: 75.0998 bits (183), Expect = 1.847e-14
Identity = 33/72 (45.83%), Postives = 54/72 (75.00%), Query Frame = 2 
Query:  884 KASMLLVTVVICFVLTELPQGIINTTAALAQCFLDS-VYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTF 1096
            + +++LV +++ F++TE PQGII+   A+    +   +Y YIGD++DLL L+NSS+NF+LYC+MS ++R TF
Sbjct:  285 RTTLMLVVILLVFLITEFPQGIISILCAIFTTDVHRYLYFYIGDVLDLLSLVNSSVNFVLYCVMSSRYRQTF 356
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: dmsr-1 (DroMyoSuppressin Receptor related [Source:UniProtKB/TrEMBL;Acc:Q8MQ19])

HSP 1 Score: 77.411 bits (189), Expect = 3.067e-15
Identity = 52/153 (33.99%), Postives = 83/153 (54.25%), Query Frame = 2 
Query:  161 WYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPH-TYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKN--KHSYFAXXXXXXXXXXXXLPNLFFQQI 610
            +Y  IH YLS  LC+ G + N  N +VL ++TM  P+N++L  +A  D V + S  IYT + + V A   C   H +Y W  F++ H+ + +  H++S  L VMLA  R  TL +      ++   +HSY+A+ +  S+  V + PN    +I
Sbjct:   29 FYHPIHAYLSIFLCVLGTIANFCNIVVLTRRTMRTPVNMILTAMASCDTVVLFSNLIYTTHYSFV-AFKFCHPKHWSYSWALFLIAHAHLSLVAHSSSVWLSVMLALVRYVTLRSRGNMGGMQVTLRHSYYAVAVTVSLVAVLNAPNFLNYKI 180

HSP 2 Score: 62.7734 bits (151), Expect = 1.703e-10
Identity = 36/107 (33.64%), Postives = 57/107 (53.27%), Query Frame = 2 
Query:  791 NGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAAL-AQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            NG   S+     E +   GS      R    + + +L+ +V   ++TELPQGI+   + + ++ F   +Y  +GDI+DL  L  S  +FI+YC MS QFR+ F  +F
Sbjct:  274 NGQRLSISVAGNEKLGRNGSLRGRGER--VDRTTHMLLAIVAVMLVTELPQGIMAVLSGMCSEEFRIYIYNNLGDILDLFSLCGSCCSFIIYCSMSGQFRNEFHRVF 378
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: dmsr-1 (DroMyoSuppressin Receptor related [Source:UniProtKB/TrEMBL;Acc:Q8MQ19])

HSP 1 Score: 77.0258 bits (188), Expect = 5.149e-15
Identity = 52/153 (33.99%), Postives = 83/153 (54.25%), Query Frame = 2 
Query:  161 WYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPH-TYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKN--KHSYFAXXXXXXXXXXXXLPNLFFQQI 610
            +Y  IH YLS  LC+ G + N  N +VL ++TM  P+N++L  +A  D V + S  IYT + + V A   C   H +Y W  F++ H+ + +  H++S  L VMLA  R  TL +      ++   +HSY+A+ +  S+  V + PN    +I
Sbjct:   29 FYHPIHAYLSIFLCVLGTIANFCNIVVLTRRTMRTPVNMILTAMASCDTVVLFSNLIYTTHYSFV-AFKFCHPKHWSYSWALFLIAHAHLSLVAHSSSVWLSVMLALVRYVTLRSRGNMGGMQVTLRHSYYAVAVTVSLVAVLNAPNFLNYKI 180

HSP 2 Score: 62.3882 bits (150), Expect = 2.621e-10
Identity = 36/107 (33.64%), Postives = 57/107 (53.27%), Query Frame = 2 
Query:  791 NGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAAL-AQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            NG   S+     E +   GS      R    + + +L+ +V   ++TELPQGI+   + + ++ F   +Y  +GDI+DL  L  S  +FI+YC MS QFR+ F  +F
Sbjct:  274 NGQRLSISVAGNEKLGRNGSLRGRGER--VDRTTHMLLAIVAVMLVTELPQGIMAVLSGMCSEEFRIYIYNNLGDILDLFSLCGSCCSFIIYCSMSGQFRNEFHRVF 378
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: dmsr-5 (DroMyoSuppressin Receptor related [Source:UniProtKB/TrEMBL;Acc:Q9XXD5])

HSP 1 Score: 67.781 bits (164), Expect = 3.852e-12
Identity = 47/128 (36.72%), Postives = 68/128 (53.12%), Query Frame = 2 
Query:  113 NDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTM-INPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWT 493
            N+S    F  L  F+  Y  +H YL   +C  GVL N L+  VL +K M +  IN LL  +++ D++ M SY IY +   +   PS     ++Y W+ F++ H T  I  HTTS  L V++A  R WT
Sbjct:   13 NNSTIYFFDQLIAFNQVYTVLHRYLCLFVCFFGVLLNSLHFYVLTRKAMRVYIINALLCAMSICDIITMTSYFIYILRFRIFDTPSTI-IGYSYPWLIFLITHVTSSIALHTTSLYLSVIMAYIR-WT 138

HSP 2 Score: 58.9214 bits (141), Expect = 2.436e-9
Identity = 24/78 (30.77%), Postives = 54/78 (69.23%), Query Frame = 2 
Query:  884 KASMLLVTVVICFVLTELPQGIINTTAALAQCFLDS-VYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCH 1114
            + +++L+ +++ F+ TE+PQG+++  +A+    + + +Y+ +G+++DL+ LIN   +FI+YC+MS  +R T  ++ C 
Sbjct:  301 RTTLMLIIMLVVFLCTEMPQGLLSILSAIYPTHVHTMIYVNVGEVLDLMSLINCLTSFIVYCVMSTTYRATVKSVLCR 378
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: CG13229 (gene:FBgn0033579 transcript:FBtr0330602)

HSP 1 Score: 103.605 bits (257), Expect = 4.354e-24
Identity = 107/335 (31.94%), Postives = 172/335 (51.34%), Query Frame = 2 
Query:  164 YKDIHGYLSAILCICGVLTNILNSIVLMKKTMIN-PINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTE-KRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITV--------FKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXL---NGPIKSV------ETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIIN-TTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            Y  IHGY+S ++CI G + NILN +VL +K M   PIN +L  +A++DM  ML Y  YT Y  +   P       +Y W   +L+H       HT S  L V LA +R   + +           HS  AI++ F +S +  LP  F  Q+           +  YH +  K+         F+I+  ++K L   +L++++  ++ V+  +S+R+ +L   N P K        ET  K+  P R  R ++       + ++LLV V++ F++TE PQG++   +  + +CF    Y   G++MDLL LIN+++ F+LY +MS+QFR TF +LF
Sbjct:   72 YNSIHGYVSLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVADMFVMLEYIPYTSYQYIYMGPGEKDL--SYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAIRHPNGGCANFLLAHSREAILLPFILSPILCLPTYFVFQVRETYDVDKVNSEAMYHVYFDKDSVLYR--FNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKYAIQLNLNETKSKK--PPRCDRRND-------RTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCYPPFGELMDLLALINAAVGFVLYGLMSKQFRTTFRSLF 393
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: CG13229 (gene:FBgn0033579 transcript:FBtr0330603)

HSP 1 Score: 103.605 bits (257), Expect = 4.354e-24
Identity = 107/335 (31.94%), Postives = 172/335 (51.34%), Query Frame = 2 
Query:  164 YKDIHGYLSAILCICGVLTNILNSIVLMKKTMIN-PINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTE-KRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITV--------FKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXL---NGPIKSV------ETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIIN-TTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            Y  IHGY+S ++CI G + NILN +VL +K M   PIN +L  +A++DM  ML Y  YT Y  +   P       +Y W   +L+H       HT S  L V LA +R   + +           HS  AI++ F +S +  LP  F  Q+           +  YH +  K+         F+I+  ++K L   +L++++  ++ V+  +S+R+ +L   N P K        ET  K+  P R  R ++       + ++LLV V++ F++TE PQG++   +  + +CF    Y   G++MDLL LIN+++ F+LY +MS+QFR TF +LF
Sbjct:   72 YNSIHGYVSLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVADMFVMLEYIPYTSYQYIYMGPGEKDL--SYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAIRHPNGGCANFLLAHSREAILLPFILSPILCLPTYFVFQVRETYDVDKVNSEAMYHVYFDKDSVLYR--FNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKYAIQLNLNETKSKK--PPRCDRRND-------RTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCYPPFGELMDLLALINAAVGFVLYGLMSKQFRTTFRSLF 393
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: CG13229 (gene:FBgn0033579 transcript:FBtr0088206)

HSP 1 Score: 103.605 bits (257), Expect = 4.354e-24
Identity = 107/335 (31.94%), Postives = 172/335 (51.34%), Query Frame = 2 
Query:  164 YKDIHGYLSAILCICGVLTNILNSIVLMKKTMIN-PINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTE-KRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITV--------FKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXL---NGPIKSV------ETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIIN-TTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            Y  IHGY+S ++CI G + NILN +VL +K M   PIN +L  +A++DM  ML Y  YT Y  +   P       +Y W   +L+H       HT S  L V LA +R   + +           HS  AI++ F +S +  LP  F  Q+           +  YH +  K+         F+I+  ++K L   +L++++  ++ V+  +S+R+ +L   N P K        ET  K+  P R  R ++       + ++LLV V++ F++TE PQG++   +  + +CF    Y   G++MDLL LIN+++ F+LY +MS+QFR TF +LF
Sbjct:   72 YNSIHGYVSLMICIFGTIANILNIMVLTRKEMAKTPINNILKWLAVADMFVMLEYIPYTSYQYIYMGPGEKDL--SYTWAVCLLVHMHFTQILHTISIGLTVTLAVWRYVAIRHPNGGCANFLLAHSREAILLPFILSPILCLPTYFVFQVRETYDVDKVNSEAMYHVYFDKDSVLYR--FNFWIHSVLIKLLPCGILIVISAVLMHVLCEASRRRLKLRDYNNPAKYAIQLNLNETKSKK--PPRCDRRND-------RTTLLLVAVLVLFLITEFPQGLLGLLSGVMEKCFFAHCYPPFGELMDLLALINAAVGFVLYGLMSKQFRTTFRSLF 393
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: MsR1 (gene:FBgn0035331 transcript:FBtr0330187)

HSP 1 Score: 86.6557 bits (213), Expect = 5.151e-18
Identity = 47/126 (37.30%), Postives = 71/126 (56.35%), Query Frame = 2 
Query:  113 NDSKCPIF--PMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFR 484
            N+   P++    +  F T YK++HGY+S ++CI G + N LN IVL ++ M +P N +L G+A++D+  ML Y  YT++  ++T   P     +Y W  FI  HS      HT S  L V LA +R
Sbjct:    5 NNETEPLYCGSGMDNFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWR 130

HSP 2 Score: 70.0922 bits (170), Expect = 1.218e-12
Identity = 35/62 (56.45%), Postives = 43/62 (69.35%), Query Frame = 2 
Query:  926 LTELPQGIINT-TAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            +TE PQGI+    A L   F    Y+ + D+MD+L LINSSINFILYC MS+QFR TF+ LF
Sbjct:  363 ITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTLLF 424
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: MsR1 (gene:FBgn0035331 transcript:FBtr0072887)

HSP 1 Score: 85.8853 bits (211), Expect = 6.540e-18
Identity = 47/126 (37.30%), Postives = 71/126 (56.35%), Query Frame = 2 
Query:  113 NDSKCPIF--PMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFR 484
            N+   P++    +  F T YK++HGY+S ++CI G + N LN IVL ++ M +P N +L G+A++D+  ML Y  YT++  ++T   P     +Y W  FI  HS      HT S  L V LA +R
Sbjct:    5 NNETEPLYCGSGMDNFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWR 130

HSP 2 Score: 69.707 bits (169), Expect = 1.280e-12
Identity = 35/62 (56.45%), Postives = 43/62 (69.35%), Query Frame = 2 
Query:  926 LTELPQGIINT-TAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLF 1108
            +TE PQGI+    A L   F    Y+ + D+MD+L LINSSINFILYC MS+QFR TF+ LF
Sbjct:  363 ITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTLLF 424
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0R3S8I5 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS466 PE=4 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 1.294e-53
Identity = 130/353 (36.83%), Postives = 193/353 (54.67%), Query Frame = 2 
Query:  104 PNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITVFK---------HKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETGVKEMIP---LRGSRHHNSV----RDPY--HKASMLLVTVVICFVLTELPQGIINTTAALA-QCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNL 1105
            P+ + S C  +P L  FD  Y+ IH YLS  +C+ G+LTN LN++VL    M +P NLLL  IAL+D V ML Y    +YL+ +T+P P + PH    I F+L  +   I  H  ST++ VMLA FR+W L     + ++  KH  F I+I   +S V  +  +  +++               Y+WF + EG    E  +F IYGC  K  S+I++   T  I+V M+++  R   L    ++     K   P     G++   ++    R+    H+ +++LV VV+ FV+TE PQG++ T  A+A  CF   VY  IGD++D+LVL+N+S NFILYC MS QFR +F  L
Sbjct:   10 PDPDLSHCTDYPGLHTFDQHYRTIHAYLSLSICLLGILTNALNAVVLTYSRMRSPTNLLLTSIALADSVTMLGYGGRDIYLHFITSPDPIATPHGQAGIYFLLFTNFTTIAAHIFSTIMTVMLAIFRSWVLYR--PQCQVLYKHIKFTIIIASILSAVMFVLCISTERVGKIDSSTLPSDRTEDYYWFAVGEGLDNLERAKFIIYGCFSKLASSILITFFTALILVAMEKARIRYLNLKHRSQNARKEGKSDKPNGDADGNKDQQNLTQKKRESRSNHRTTVMLVAVVVSFVITEAPQGVLITMTAIADDCFTYKVYAPIGDLIDILVLLNASTNFILYCAMSAQFRKSFQEL 360
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0R3TQ48 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9642 PE=4 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 3.550e-51
Identity = 126/354 (35.59%), Postives = 187/354 (52.82%), Query Frame = 2 
Query:  104 PNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITVFK---------HKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETGVKEMIPLRGSRHHNSVRD----------PYHKASMLLVTVVICFVLTELPQGIINTTAALA-QCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNL 1105
            P+ + S C  +P L  FD  YK IH YLS  +C+ G+ TN LN++VL    M +P NLLL  IA++D + ML Y    +YL+ VT+P P + PH    I F+L  +   I  H  ST++ VMLA FR+W L     + ++  KH    I+I   +S    +  +  +++               Y WF + EG    E   F IYGC  K  S+I++   T  I++ M+++  R  +L    +S     K    L    + N+ +             H+ +++LV VV+ FV+TE PQG++ T  A+A +CF   VY  IGD++D+LVL+N+S NFILYC MS QFR +F  L
Sbjct:   10 PDPDLSDCTDYPGLHTFDQHYKTIHAYLSLSICLLGIFTNALNAVVLTYSRMRSPTNLLLTSIAIADSITMLGYGGRDIYLHFVTSPDPKTAPHGQAGIYFLLFTNFTTIAAHIASTIMTVMLAIFRSWVLYR--PQCQVLYKHIKVTIIIASMLSAAMFILCISTERVGKIDSSTLQSDGTEDYFWFGVGEGLDNLERANFIIYGCFSKLASSILITFFTALILIAMEKARIRYMKLKHRPQSARKDRKND-KLDDDAYENNDQQYVAQKKRESRGNHRTTVMLVAVVVSFVITEAPQGVLITMTAIADECFTYKVYAPIGDLIDILVLLNASTNFILYCAMSAQFRKSFQEL 360
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0X3PEE5 (Serpentine type 7TM GPCR chemoreceptor Srw OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS3015 PE=4 SV=1)

HSP 1 Score: 184.882 bits (468), Expect = 3.571e-50
Identity = 128/371 (34.50%), Postives = 196/371 (52.83%), Query Frame = 2 
Query:  125 CPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITVF-------KHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNG--------PIKSVETGVKEMIPLRGS-----------------------RHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINT-TAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHFC 1120
            C  +P L +FD  YK IH YLS  +C+ G  TN+LN+IVL ++TM +P N+LL  IAL+D + M+ Y +  VYL+ +T+P P    H    I F+L+ + ++I  H  +T++ VML++FR W L N    +++  +      +     SF+ ++P  F   +            +  WF ++ G +  E   F IYGC++K  ++  + + T  I+  M+R+ +R   L          P  +VE   KE   L G                        R   +      + +++LV VV+ FV+TE PQG+INT  A +  CFL +VY+ IGD++DLLVL+NSS NFILYC MSQQFR +F +L  + C
Sbjct:   22 CTRYPFLEDFDRHYKPIHAYLSLSICLFGTATNLLNAIVLTQRTMRSPTNMLLTIIALADSITMIGYLLKDVYLHFITSPMPEGADHGRAAIYFVLISNFVIIGGHIVATIVTVMLSAFRCWILYN--PRRQITYREIAITSLCAILASFILTIPGFFSYTVVAVAAGGGNSSEQNWWFEVRNGTEYLESANFAIYGCIIKLAASFFIALFTGLILGTMRRARQRYLNLQRVSRQSIAPPGVAVENKDKEGPRLAGDGEQAAQDTADGTERLLIQKDAERRREGAKMRSNQRTTIMLVAVVVSFVITEAPQGVINTLVAKMGNCFLYTVYVPIGDLLDLLVLLNSSTNFILYCAMSQQFRASFRHLMENTC 390
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: U6IXQ6 (Neuropeptide F-like receptor OS=Echinococcus granulosus OX=6210 GN=EGR_07920 PE=4 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 7.624e-50
Identity = 125/349 (35.82%), Postives = 189/349 (54.15%), Query Frame = 2 
Query:  104 PNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKNKHSYFAXXXX----------XXXXXXXXLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXL----NGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQ-CFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNL 1105
            P  + S C  +P L  FD  YK IH YLS  +C  G+ TN LN+++L    M +P NLLL  IA++D V M++Y    VYL+ +T+P P + PH    I F+LL +   I  H  ST++ VMLA+FR W L     +   K+     A+  V           ++      P +  + +T     Y+WF ++EG    +   F IYGC  K  S++++   T  I+  M+++ +R  +L    +GP K++ +  ++ +   G           H+ +++LV VV+ F++TE PQG+I T  A+   CFL + Y  IGD++DLLVL+NSS NFILYC MS QFR +F  L
Sbjct:   10 PEPDLSNCTRYPGLEAFDLHYKTIHAYLSLGICFFGIFTNTLNAVILTHNHMRSPTNLLLTSIAIADSVTMIAYVAKDVYLHFITSPDPITIPHGRGGIYFVLLTNFTAIGAHIFSTIMTVMLAAFRCWVLYRPQCQVSYKHIKQTVAVAAVLSFAMFVLGISTLVVGKLAPPIVPKNVT---KDYYWFAVREGLDYVDRANFVIYGCFSKLASSLLIAFFTGLILAAMEKARRRYLKLKHGPSGPKKTLMS--EQTMDTEGKDVGKHESRGNHRTTVMLVAVVVSFIITETPQGVITTVVAIQDYCFLYTFYAPIGDLLDLLVLLNSSTNFILYCAMSAQFRKSFKEL 353
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A068Y740 (Neuropeptide receptor OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000818600 PE=4 SV=1)

HSP 1 Score: 182.185 bits (461), Expect = 1.057e-49
Identity = 125/346 (36.13%), Postives = 188/346 (54.34%), Query Frame = 2 
Query:  104 PNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKN-KHSYFAXXXXXXXXXXXXLPNLFFQQITVF------KHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXL----NGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQ-CFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNL 1105
            P  + S C  +P L  FD  YK IH YLS  +C  G+ TN LN+++L    M +P NLLL  IA++D V M++Y    VYL+ +T+P P + PH    I F+LL +   I  H  ST+  VMLA+FR W L     +   K+ K +     ++    FV  +  L   ++            Y+WF ++EG    +   F IYGC  K  S++++   T  I+  M+++ +R  +L    +GP K++ +  ++ +   G           H+ +++LV VV+ F++TE PQG+I T  A+   CFL + Y  IGD++DLLVL+NSS NFILYC MS QFR +F  L
Sbjct:   10 PEPDLSNCTRYPGLEAFDLHYKTIHAYLSLGICFFGIFTNTLNAVILTHNHMRSPTNLLLTSIAIADSVTMIAYVAKDVYLHFITSPDPITIPHGRGGIYFVLLTNFTAIGAHIFSTITTVMLAAFRCWVLYRPQCQVSYKHIKQTVAVAALLSFAMFVLGISTLVVGKLAPLIVPKNVTKDYYWFAVREGLDYVDRANFVIYGCFSKLASSLLIAFFTGLILAAMEKARRRYLKLKHGPSGPKKTLMS--EQTMDTEGKDVGKRESRGNHRTTVMLVAVVVSFIITEAPQGVITTVVAIQDYCFLYAFYAPIGDLLDLLVLLNSSTNFILYCAMSAQFRKSFKEL 353
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000046883.1 (SMESG000046883.1)

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 361/362 (99.72%), Postives = 362/362 (100.00%), Query Frame = 2 
Query:   41 MYVNNDSVHDLNSCMKFFSNKPNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHFCLK 1126
            MYVNNDSVHDLNSCMKFFSNKPNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVV+LASFRAWTLTNITTEKRLKNKHSYFAIVIVFSISFVFSLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKSLSTIVLVILTTFIIVVMKRSSKRKRRLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHFCLK
Sbjct:    1 MYVNNDSVHDLNSCMKFFSNKPNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVLLASFRAWTLTNITTEKRLKNKHSYFAIVIVFSISFVFSLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKSLSTIVLVILTTFIIVVMKRSSKRKRRLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHFCLK 362
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000046875.1 (SMESG000046875.1)

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 361/362 (99.72%), Postives = 362/362 (100.00%), Query Frame = 2 
Query:   41 MYVNNDSVHDLNSCMKFFSNKPNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHFCLK 1126
            MYVNNDSVHDLNSCMKFFSNKPNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVV+LASFRAWTLTNITTEKRLKNKHSYFAIVIVFSISFVFSLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKSLSTIVLVILTTFIIVVMKRSSKRKRRLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHFCLK
Sbjct:    1 MYVNNDSVHDLNSCMKFFSNKPNINDSKCPIFPMLTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVLLASFRAWTLTNITTEKRLKNKHSYFAIVIVFSISFVFSLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKSLSTIVLVILTTFIIVVMKRSSKRKRRLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHFCLK 362
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000010008.1 (SMESG000010008.1)

HSP 1 Score: 122.865 bits (307), Expect = 2.939e-31
Identity = 103/357 (28.85%), Postives = 180/357 (50.42%), Query Frame = 2 
Query:  143 LTEFDTWYKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYL----NLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKN-KHSYFAXXXXXXXXXXXXLPNLFFQQI---------------------TVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETG-----VKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAA-LAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHF 1117
            + +F T YK+IH  L  I+C  GV++NI+N I+L +K M +P N LL  +A++D   M  Y  + +Y      L+ +P        YLW  +++++  I    H  S  ++V LA+FR   +  +     L N   +Y ++  +  I+ + ++P+    +I                     T   +  ++ V     QK   + F++    +K L  +++ IL+  II+ +K  +K+ ++L    K+ +       +K   PL   R   +V     + + +L+ +V+ F+LT LPQ I+ +    L +CF D VY  +GD++D+L L NS INF+LYC+MS+QFR+ F  +FCH 
Sbjct:   14 MRQFQTQYKNIHENLCLIICPLGVISNIMNVIILNQKVMRSPTNFLLTVLAITDGFLMALYIPFALYFLKKNYLLGSP--------YLWALYMMVYVIIQNILHVISIGIIVALAAFRVLYIRCLVRCNELCNITRAYISVASIVLIAVLLTIPSAIAHKIRPMCMLPNSTDIQEIDPDSDLTCVNYVNYYRVNYVDNQKIRRLLFWVSAIFIKLLPVVLVTILSIIIIMAIKSRAKKMKKLKSNSKNTKGSRDNIEMKSNQPLVEKRTVKTVDKDGIRTTRMLLVIVLIFMLTYLPQAILLSLGGILGRCFTDEVYDRLGDVLDMLTLTNSGINFVLYCLMSRQFREAFIKIFCHL 362
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000046994.1 (SMESG000046994.1)

HSP 1 Score: 97.0561 bits (240), Expect = 4.307e-22
Identity = 96/331 (29.00%), Postives = 171/331 (51.66%), Query Frame = 2 
Query:  164 YKDIHGYLSAILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTI----YTVYLNLVTAPSPC-SYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKN-KHSYFAXXXXXXXXXXXXLPNLFFQQIT-----VFKHK---YHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCH 1114
            +  I GY SA++CI G+LTN+ N IVL + TM +P N +L  +A++D++ M+ Y      Y ++ N++    P  S     +W  + L   + V+ +H  +    V+LA  R   L+  T   ++ N +++  +I IV  +S +F++PN+   ++       F  +   +H F   +   K E I F+I   + K + + VL +LT  +I+ M              + +     ++I    SR  +  +   ++ +++L+ VV+ F++ ELP  I+  ++  +Q  L+ +Y  +GD++D L L+N SINFILY  MS+QFR  F   FC 
Sbjct:   23 FYTIFGYGSALMCIIGILTNLANIIVLSQPTMRSPTNWVLTWLAIADLLTMVVYLPNVCHYYIFNNIIL---PLFSVTSNKIWAYYRLTIISFVLISHAAAVWFTVVLAVIRYLHLSLPTIGPQIANIENTTISIAIVSVLSLIFTIPNMMINEVNRCVGFTFDKQSKAFHTFYEIKSINKLE-INFWIQSIIFKIVPSFVLSVLTILLILKM--------------QHIGKRRNKLI----SRSDSQKKKKENRVTLMLLMVVVLFLIVELPHAILMLSSNFSQTCLE-IYETLGDLIDFLTLVNESINFILYTTMSKQFRRVFIMTFCR 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000077726.1 (SMESG000077726.1)

HSP 1 Score: 80.1073 bits (196), Expect = 2.108e-16
Identity = 83/309 (26.86%), Postives = 135/309 (43.69%), Query Frame = 2 
Query:  209 GVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTVYLNLVTAPSPCSYPHTYL--WIT-FILLHSTIVICTHTTSTLLVVMLASFRAWTLTNITTEKRLKNKHSYFAXXXXXXXXXXXXLPNLFFQQITVFKHKYHWFVIKEGFQKEEDIQFFIYGCVVKXXXXXXXXXXXXXXXXXMXXXXXXXXXLNGPIKSVETGVKEMIPLR---GSRHHNSVRDPYHKASMLLVTVVICFVLTELPQGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRDTFSNLFCHF 1117
            G++ ++ N ++L  K M+ P   +L  I + D+  M+ Y  Y +Y ++    +PC      +  W   F+ ++  IV  +H TS  L +ML+ FR   L N+     L  K   F   IV                +T F    ++F I     K+ D     YG V     TI +       I  +         L+    ++   +K  I L    G + H S        +  LV +V+ F+  E PQGII   +A    F   +Y  +GD++DL+ +I +  NF +YCIM +++R+TF N+ C F
Sbjct:   44 GLILSVFNIVILNIKNMLTPTTYMLTRIGVMDIFTMVIYIPYVLYFHIF---NPCDIYRGIVKRWAAYFLFIYIIIVNLSHCTSIWLAIMLSGFRLRCLRNLNFNIVLAWKQVRFLSWIVLV--------------VTCFISILNYFTINLIKYKDPD-----YGTV----YTIKMTKHYLIGIQALIVKIIPSITLSVLAGAITFELKRFIRLGKCIGKQRHIS------NTTYTLVALVLLFIFLESPQGIIIFISAFNMLFFTEIYNPLGDMLDLMTIIRTIANFCMYCIMDRRYRNTFVNIICPF 320
The following BLAST results are available for this feature:
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dmsr-85.286e-2927.78DroMyoSuppressin Receptor related [Source:UniProt... [more]
dmsr-71.168e-1535.61DroMyoSuppressin Receptor related [Source:UniProt... [more]
dmsr-13.067e-1533.99DroMyoSuppressin Receptor related [Source:UniProt... [more]
dmsr-15.149e-1533.99DroMyoSuppressin Receptor related [Source:UniProt... [more]
dmsr-53.852e-1236.72DroMyoSuppressin Receptor related [Source:UniProt... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG132294.354e-2431.94gene:FBgn0033579 transcript:FBtr0330602[more]
CG132294.354e-2431.94gene:FBgn0033579 transcript:FBtr0330603[more]
CG132294.354e-2431.94gene:FBgn0033579 transcript:FBtr0088206[more]
MsR15.151e-1837.30gene:FBgn0035331 transcript:FBtr0330187[more]
MsR16.540e-1837.30gene:FBgn0035331 transcript:FBtr0072887[more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3S8I51.294e-5336.83G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A0R3TQ483.550e-5135.59G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A0X3PEE53.571e-5034.50Serpentine type 7TM GPCR chemoreceptor Srw OS=Schi... [more]
U6IXQ67.624e-5035.82Neuropeptide F-like receptor OS=Echinococcus granu... [more]
A0A068Y7401.057e-4936.13Neuropeptide receptor OS=Echinococcus multilocular... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000046883.10.000e+099.72SMESG000046883.1[more]
SMESG000046875.10.000e+099.72SMESG000046875.1[more]
SMESG000010008.12.939e-3128.85SMESG000010008.1[more]
SMESG000046994.14.307e-2229.00SMESG000046994.1[more]
SMESG000077726.12.108e-1626.86SMESG000077726.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030212 ID=SMED30030212|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1225bp
GAAATCTTGCTTTCAAACATAGTTATTATCAATACAAGAAATGTATGTCA
ACAATGATTCTGTCCATGATCTGAATTCATGTATGAAGTTCTTTAGCAAT
AAACCCAACATCAATGACTCAAAATGTCCAATATTCCCAATGCTTACAGA
GTTTGACACATGGTATAAAGACATCCACGGCTACCTTAGTGCCATTCTTT
GTATTTGTGGTGTTCTGACGAACATTTTAAATTCGATAGTACTTATGAAG
AAAACTATGATAAATCCTATCAACTTACTTCTGCTTGGAATTGCTCTTTC
GGACATGGTTAAAATGCTCAGCTATACAATTTATACGGTCTATTTAAATC
TCGTTACTGCTCCCAGTCCATGTTCGTATCCCCATACATATTTATGGATA
ACTTTCATTCTTCTTCACTCAACTATCGTGATTTGCACTCACACCACTTC
GACACTTCTCGTCGTCATGTTAGCGAGTTTTCGAGCTTGGACATTGACAA
ATATAACAACAGAAAAACGTTTAAAAAATAAACATTCATATTTTGCAATT
GTAATTGTATTTTCGATTTCGTTTGTGTTTTCATTGCCGAATCTGTTTTT
CCAACAAATTACGGTTTTCAAACACAAATATCATTGGTTTGTGATCAAGG
AAGGATTTCAGAAAGAAGAAGACATCCAGTTCTTTATTTACGGATGCGTA
GTCAAGTCATTGTCAACGATTGTTTTGGTGATTTTGACAACGTTTATTAT
CGTGGTCATGAAAAGGTCGAGCAAACGAAAACGGAGATTAAATGGACCGA
TTAAAAGCGTCGAAACCGGTGTTAAAGAAATGATACCTTTGAGGGGTTCA
CGGCATCATAATTCTGTTCGAGATCCCTATCATAAGGCATCGATGCTCCT
TGTAACGGTTGTCATTTGTTTTGTGTTGACTGAGTTACCGCAAGGAATAA
TTAACACAACTGCTGCATTAGCACAGTGTTTTTTAGACAGTGTTTACATT
TATATTGGTGATATAATGGATCTGCTTGTTTTAATTAACTCTTCAATTAA
TTTCATTCTATATTGCATCATGTCCCAGCAATTTCGTGATACCTTCAGTA
ATTTATTCTGTCATTTTTGTTTGAAGTAAAAGTACAATTTGTAAACTAGT
CAAACTGGTGAACATTTTTCTTTATTCATCATTTAAACAAGAATTTATTT
GTACGTATTTTTAAAAACAAATATT
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protein sequence of SMED30030212-orf-1

>SMED30030212-orf-1 ID=SMED30030212-orf-1|Name=SMED30030212-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=363bp
MYVNNDSVHDLNSCMKFFSNKPNINDSKCPIFPMLTEFDTWYKDIHGYLS
AILCICGVLTNILNSIVLMKKTMINPINLLLLGIALSDMVKMLSYTIYTV
YLNLVTAPSPCSYPHTYLWITFILLHSTIVICTHTTSTLLVVMLASFRAW
TLTNITTEKRLKNKHSYFAIVIVFSISFVFSLPNLFFQQITVFKHKYHWF
VIKEGFQKEEDIQFFIYGCVVKSLSTIVLVILTTFIIVVMKRSSKRKRRL
NGPIKSVETGVKEMIPLRGSRHHNSVRDPYHKASMLLVTVVICFVLTELP
QGIINTTAALAQCFLDSVYIYIGDIMDLLVLINSSINFILYCIMSQQFRD
TFSNLFCHFCLK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000420parapharyngeal region
PLANA:0003104enteric muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR0194277TM_GPCR_serpentine_rcpt_Srw
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0008528G-protein coupled peptide receptor activity
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 77..98
score: 20.87
coord: 165..186
score: 20.88
coord: 283..307
score: 22.75
coord: 323..349
score: 27.11
coord: 45..69
score: 20.06
IPR0194277TM GPCR, serpentine receptor class w (Srw)PFAMPF103247TM_GPCR_Srwcoord: 50..357
e-value: 9.1E-32
score: 110.6
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 34..362
e-value: 1.3E-41
score: 144.6
NoneNo IPR availablePANTHERPTHR46273FAMILY NOT NAMEDcoord: 33..357
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 45..352
e-value: 8.67519E-44
score: 151.246
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 33..360
NoneNo IPR availableTMHMMTMhelixcoord: 45..67
NoneNo IPR availableTMHMMTMhelixcoord: 214..239
NoneNo IPR availableTMHMMTMhelixcoord: 319..341
NoneNo IPR availableTMHMMTMhelixcoord: 122..144
NoneNo IPR availableTMHMMTMhelixcoord: 80..102
NoneNo IPR availableTMHMMTMhelixcoord: 285..304
NoneNo IPR availableTMHMMTMhelixcoord: 165..187
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 60..341
score: 17.523