ATP-dependent zinc metalloprotease FtsH

Overview
NameATP-dependent zinc metalloprotease FtsH
Smed IDSMED30030149
Length (bp)3141
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ATP-dependent zinc metalloprotease FtsH (SMED30030149) t-SNE clustered cells

Violin plots show distribution of expression levels for ATP-dependent zinc metalloprotease FtsH (SMED30030149) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ATP-dependent zinc metalloprotease FtsH (SMED30030149) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ATP-dependent zinc metalloprotease FtsH (SMED30030149) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030149

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30030149SMESG000077945.1 SMESG000077944.1 dd_Smed_v4_3475_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30030149SMESG000077945.1 SMESG000077944.1 dd_Smed_v4_3475_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Human
Match: SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:HGNC Symbol;Acc:HGNC:11237])

HSP 1 Score: 459.144 bits (1180), Expect = 2.050e-148
Identity = 220/452 (48.67%), Postives = 331/452 (73.23%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSF-QVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRH+ +D P L+ER+E+F  +L K+ +  Q S    S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERV+AG+  K++ LS+ E+K+ A+HE+GH LVGWML++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+++F+ +TSGA++DL+KV+++A++MV+++GM+  +G  SF +  E     G  PFS+  Q +++ EA  ++  AY+  E V++ N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  170 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHL-KSLKLTQSST-FYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 617
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Human
Match: SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:HGNC Symbol;Acc:HGNC:11237])

HSP 1 Score: 459.914 bits (1182), Expect = 2.097e-148
Identity = 220/452 (48.67%), Postives = 331/452 (73.23%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSF-QVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRH+ +D P L+ER+E+F  +L K+ +  Q S    S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERV+AG+  K++ LS+ E+K+ A+HE+GH LVGWML++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+++F+ +TSGA++DL+KV+++A++MV+++GM+  +G  SF +  E     G  PFS+  Q +++ EA  ++  AY+  E V++ N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  192 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHL-KSLKLTQSST-FYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 639
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Human
Match: SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:HGNC Symbol;Acc:HGNC:11237])

HSP 1 Score: 460.299 bits (1183), Expect = 1.191e-147
Identity = 220/452 (48.67%), Postives = 331/452 (73.23%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSF-QVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRH+ +D P L+ER+E+F  +L K+ +  Q S    S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERV+AG+  K++ LS+ E+K+ A+HE+GH LVGWML++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+++F+ +TSGA++DL+KV+++A++MV+++GM+  +G  SF +  E     G  PFS+  Q +++ EA  ++  AY+  E V++ N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  262 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHL-KSLKLTQSST-FYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 709
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Human
Match: SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:HGNC Symbol;Acc:HGNC:11237])

HSP 1 Score: 459.529 bits (1181), Expect = 7.669e-147
Identity = 219/452 (48.45%), Postives = 331/452 (73.23%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHS-GNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRH+ +D P L+ER+E+F  +L K+ +  Q S    S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERV+AG+  K++ LS+ E+K+ A+HE+GH LVGWML++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+++F+ +TSGA++DL+KV+++A++MV+++GM+  +G  SF   ++     G  PFS+  Q +++ EA  ++  AY+  E V++ N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  306 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHL-KSLKLTQSST-FYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 753
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Human
Match: SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:HGNC Symbol;Acc:HGNC:11237])

HSP 1 Score: 446.432 bits (1147), Expect = 6.556e-142
Identity = 219/452 (48.45%), Postives = 326/452 (72.12%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSF-QVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL       KLGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRH+ +D P L+ER+E+F  +L K+ +  Q S    S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERV+AG+  K++ LS+ E+K+ A+HE+GH LVGWML++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+++F+ +TSGA++DL+KV+++A++MV+++GM+  +G  SF +  E     G  PFS+  Q +++ EA  ++  AY+  E V++ N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  306 VSFKDVAGMHEAKLEVREFVDYL-------KLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHL-KSLKLTQSST-FYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 746
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Celegans
Match: ppgn-1 (ParaPleGiN AAA protease family; Paraplegin [Source:UniProtKB/TrEMBL;Acc:G5EDB6])

HSP 1 Score: 446.047 bits (1146), Expect = 1.000e-142
Identity = 228/452 (50.44%), Postives = 312/452 (69.03%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDED--------QTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            FKD+AG   AK+EI+EF+ YL NP +F KLGA+LP+GA+L GPPGCGKTLL KALA+E+ VPF   +G +F+++ GG  A+++R +F++A S AP II+IDEIDAIG+ R   +G             QTLNQLLVEMDGM S  GV+V A+TNR D+LDKAL+RPGRFDRHI +D P + ERK++F LY+ K +  +  + +  S RL+  TPG TGADI N+CNE+A+ A+      VT++  + AL+RV+AGSE ++R L E ER++ AYHEAGH LVGWML++ D +LKV+IIPRT   LGF Q   ++K+L + D L D + ++LGGR AE++ F   TSGA++DL+KV+K A+  V+ +GMS  VG  SF  TE  +     P+SK   +  + EA  I+  A +   ++IK N +KLE IA  LLK+E L +ED++ LIG   FG
Sbjct:  284 FKDVAGCSEAKVEIREFVDYLKNPGRFTKLGAKLPRGALLTGPPGCGKTLLAKALAAESTVPFISMNGSEFVEVIGGLGASRIRGLFKEARSRAPCIIYIDEIDAIGRKRSEGAGAGGGFGGGSGEEEQTLNQLLVEMDGMGSGNGVVVLASTNRADVLDKALLRPGRFDRHISIDLPTVLERKDMFELYMRKIK--LDHAPQEYSQRLAALTPGFTGADIMNVCNESAIRAASNKCHVVTHKDMEYALDRVLAGSEKRSRSLVEEEREVVAYHEAGHALVGWMLEHTDALLKVTIIPRTSAALGFAQYSPRDKHLFSKDELFDRMCMMLGGRCAENLKFGRATSGAQDDLQKVTKSAYAQVKLYGMSSIVGPLSFPNTEGFQIK---PYSKKFASTFDQEATLIVAKANEATTDLIKNNMDKLETIAQALLKREVLNYEDVKKLIGTPKFG 730
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Celegans
Match: ppgn-1 (ParaPleGiN AAA protease family; Paraplegin [Source:UniProtKB/TrEMBL;Acc:G5EDB6])

HSP 1 Score: 446.047 bits (1146), Expect = 1.000e-142
Identity = 228/452 (50.44%), Postives = 312/452 (69.03%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDED--------QTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            FKD+AG   AK+EI+EF+ YL NP +F KLGA+LP+GA+L GPPGCGKTLL KALA+E+ VPF   +G +F+++ GG  A+++R +F++A S AP II+IDEIDAIG+ R   +G             QTLNQLLVEMDGM S  GV+V A+TNR D+LDKAL+RPGRFDRHI +D P + ERK++F LY+ K +  +  + +  S RL+  TPG TGADI N+CNE+A+ A+      VT++  + AL+RV+AGSE ++R L E ER++ AYHEAGH LVGWML++ D +LKV+IIPRT   LGF Q   ++K+L + D L D + ++LGGR AE++ F   TSGA++DL+KV+K A+  V+ +GMS  VG  SF  TE  +     P+SK   +  + EA  I+  A +   ++IK N +KLE IA  LLK+E L +ED++ LIG   FG
Sbjct:  284 FKDVAGCSEAKVEIREFVDYLKNPGRFTKLGAKLPRGALLTGPPGCGKTLLAKALAAESTVPFISMNGSEFVEVIGGLGASRIRGLFKEARSRAPCIIYIDEIDAIGRKRSEGAGAGGGFGGGSGEEEQTLNQLLVEMDGMGSGNGVVVLASTNRADVLDKALLRPGRFDRHISIDLPTVLERKDMFELYMRKIK--LDHAPQEYSQRLAALTPGFTGADIMNVCNESAIRAASNKCHVVTHKDMEYALDRVLAGSEKRSRSLVEEEREVVAYHEAGHALVGWMLEHTDALLKVTIIPRTSAALGFAQYSPRDKHLFSKDELFDRMCMMLGGRCAENLKFGRATSGAQDDLQKVTKSAYAQVKLYGMSSIVGPLSFPNTEGFQIK---PYSKKFASTFDQEATLIVAKANEATTDLIKNNMDKLETIAQALLKREVLNYEDVKKLIGTPKFG 730
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Celegans
Match: spg-7 (AFG3-like protein spg-7 [Source:UniProtKB/Swiss-Prot;Acc:Q9N3T5])

HSP 1 Score: 416.387 bits (1069), Expect = 4.570e-131
Identity = 214/447 (47.87%), Postives = 308/447 (68.90%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAI---GKTRGFHSGESDEDQTLNQLLVEMDGMES-VAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F D+AG   AKIEI EF+ +L NP ++  LGA++PKGA+L GPPG GKTLL KA A EANVPF   SG +F++M  G   A++R++F  A  ++P I+FIDEIDA+      +G   G S+++ TLNQLLVEMDG  +  + VIV AATNRVDILD AL+RPGRFDR I V  P ++ R  +F ++L   +  +  ++  LS +L+  TPG +GADISN+CNEAA+IA+R     ++N+ F+ A+ERV+AG E KT+ L + E+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL + D L+D + + LGGR AE I F  IT+GA++DL+KV+++A++ V ++GMSEKVG  SF+     E + + P+S+ T  LI+ E   ++++A ++  +++   R  +E++A+ LL+KE L  ED+  L+G RPF
Sbjct:  292 FADVAGCEEAKIEIMEFVNFLKNPQQYKDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDMFSMARKNSPCILFIDEIDAVGRKRGGKGGMGGHSEQENTLNQLLVEMDGFTTDESSVIVIAATNRVDILDSALLRPGRFDRQIYVPVPDIKGRASIFRVHLGPLRTSLDKTV--LSRKLAAHTPGFSGADISNVCNEAALIAARDANHEISNKHFEQAIERVVAGMEKKTQVLQKEEKKTVAYHEAGHAIAGWFLQHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYSKDQLLDRMCMTLGGRVAEEIFFGRITTGAQDDLQKVTQMAYSQVVKFGMSEKVGPLSFETPAPGEMAFDKPYSEATAQLIDQEVRDLVMNALRRTRDLLLEKRSDIERVALRLLEKEILNREDMIELVGKRPF 735
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Celegans
Match: ymel-1 (ATP-dependent zinc metalloprotease YME1 homolog [Source:UniProtKB/Swiss-Prot;Acc:P54813])

HSP 1 Score: 327.791 bits (839), Expect = 1.700e-98
Identity = 186/447 (41.61%), Postives = 274/447 (61.30%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAG-SESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKY---TQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLI 3120
            + TF D+ G+  AK+E++E + YL +P K+ +LG RLPKG +L+GPPG GKTLL +A+A EA VPFF+ +G +F ++  GQ A ++R++F KA + AP IIFIDEID++G  R  +S     +QT+NQLL EMDG     G+IV AATNRVD LDKAL+RPGRFD  + V  P L  R ++F  YLSK   H  G    +   L+  + G TGADI N+ N+AA+ A+  +   VT    D A +RV+ G + +  R   E   +  AYHEAGH LV    K A P+ KV+IIPR   L        ++ Y      ++  + V++GGR AE + F  D +T+GA +DL K ++LA  MV+ +GMS+KVG   F  T QD  S     S     T  LI+ E N+++  +YK+A+ +++  +++ + +A  LL+ E+L+ ++++ +I
Sbjct:  244 QVTFDDVRGMDEAKLEVEEIVDYLKDPEKYSRLGGRLPKGVLLVGPPGTGKTLLARAIAGEAQVPFFHTAGSEFDEVLVGQGARRVRDLFDKAKARAPCIIFIDEIDSVGSKRVSNSIHPYANQTINQLLSEMDGFTRNEGIIVIAATNRVDDLDKALLRPGRFDVRVTVPKPDLAGRVDIFNFYLSK-IVHSGGIDPKV---LAKGSTGFTGADIENMVNQAALKAATDNAVEVTMAYLDEARDRVLMGPARTGGRIPDEEANRNTAYHEAGHTLVSLYTKDATPLHKVTIIPRGQSLGHTAMLPEKDSYQLTKAQMLATLDVMMGGRVAEELIFGDDKVTTGAADDLSKATQLAVQMVKVFGMSDKVGLRDF--TAQDNESALVKVSDLAPQTAELIDAEINRVLQESYKRAKVILETKKKEHQLLAEALLEYETLSADEVKRVI 684
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Celegans
Match: ymel-1 (ATP-dependent zinc metalloprotease YME1 homolog [Source:UniProtKB/Swiss-Prot;Acc:P54813])

HSP 1 Score: 327.791 bits (839), Expect = 1.700e-98
Identity = 186/447 (41.61%), Postives = 274/447 (61.30%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAG-SESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKY---TQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLI 3120
            + TF D+ G+  AK+E++E + YL +P K+ +LG RLPKG +L+GPPG GKTLL +A+A EA VPFF+ +G +F ++  GQ A ++R++F KA + AP IIFIDEID++G  R  +S     +QT+NQLL EMDG     G+IV AATNRVD LDKAL+RPGRFD  + V  P L  R ++F  YLSK   H  G    +   L+  + G TGADI N+ N+AA+ A+  +   VT    D A +RV+ G + +  R   E   +  AYHEAGH LV    K A P+ KV+IIPR   L        ++ Y      ++  + V++GGR AE + F  D +T+GA +DL K ++LA  MV+ +GMS+KVG   F  T QD  S     S     T  LI+ E N+++  +YK+A+ +++  +++ + +A  LL+ E+L+ ++++ +I
Sbjct:  244 QVTFDDVRGMDEAKLEVEEIVDYLKDPEKYSRLGGRLPKGVLLVGPPGTGKTLLARAIAGEAQVPFFHTAGSEFDEVLVGQGARRVRDLFDKAKARAPCIIFIDEIDSVGSKRVSNSIHPYANQTINQLLSEMDGFTRNEGIIVIAATNRVDDLDKALLRPGRFDVRVTVPKPDLAGRVDIFNFYLSK-IVHSGGIDPKV---LAKGSTGFTGADIENMVNQAALKAATDNAVEVTMAYLDEARDRVLMGPARTGGRIPDEEANRNTAYHEAGHTLVSLYTKDATPLHKVTIIPRGQSLGHTAMLPEKDSYQLTKAQMLATLDVMMGGRVAEELIFGDDKVTTGAADDLSKATQLAVQMVKVFGMSDKVGLRDF--TAQDNESALVKVSDLAPQTAELIDAEINRVLQESYKRAKVILETKKKEHQLLAEALLEYETLSADEVKRVI 684
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Fly
Match: Spg7 (gene:FBgn0024992 transcript:FBtr0070502)

HSP 1 Score: 449.899 bits (1156), Expect = 3.442e-143
Identity = 218/454 (48.02%), Postives = 324/454 (71.37%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRG----FHSGESDE-DQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNF------PFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F+D+AGL  AK E++EF+ YL +P K+ +LGA++P+GA+LLGPPGCGKTLL KA+A+EA VPF   +G +FI+M GG  AA++R++F++    AP II+IDEIDAIG+ R        G S E +QTLNQLLVEMDGM +  GV++ A+TNR DILDKAL+RPGRFDRHIL+D P L ERKE+F  +LS  +  ++      S RL+  TPG +GADI+N+CNEAA+ A+R     V+++  + A+ER++ G+E ++  LS +ERK+ AYHE+GH LVGWML  +D +LKV+I+PRT   LGF Q     ++L + + L D++ + LGGRAAE++ F+ IT+GA+NDL+KV+K+A++ ++++GM++ +G    +  ++ E  G        PFS+  +++I+ EA  ++ SAY+  E ++  +R+KLEK+A  LL+KE+L ++ +  LIGP P+
Sbjct:  340 FRDVAGLSEAKQEVKEFVDYLKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQVPFLSMNGSEFIEMIGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMATKEGVLMLASTNRADILDKALLRPGRFDRHILIDLPTLAERKEIFEKHLSSVK--LESPPTTFSQRLARLTPGFSGADIANVCNEAALHAARNTQMEVSSKNLEYAVERLVGGTEKRSHALSLAERKVIAYHESGHALVGWMLPNSDILLKVTIVPRTSLALGFAQYTPSEQHLYSKEELFDKMCMALGGRAAENLVFNRITTGAQNDLEKVTKIAYSQIKKFGMNDTLGPIYVRDADETEGGGAMGSGGKKPFSRAMESMIDNEARHVVASAYQTTEGILTTHRDKLEKLAEALLEKETLDYDQVVQLIGPPPY 791
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Fly
Match: Spg7 (gene:FBgn0024992 transcript:FBtr0345716)

HSP 1 Score: 449.899 bits (1156), Expect = 3.442e-143
Identity = 218/454 (48.02%), Postives = 324/454 (71.37%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRG----FHSGESDE-DQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNF------PFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F+D+AGL  AK E++EF+ YL +P K+ +LGA++P+GA+LLGPPGCGKTLL KA+A+EA VPF   +G +FI+M GG  AA++R++F++    AP II+IDEIDAIG+ R        G S E +QTLNQLLVEMDGM +  GV++ A+TNR DILDKAL+RPGRFDRHIL+D P L ERKE+F  +LS  +  ++      S RL+  TPG +GADI+N+CNEAA+ A+R     V+++  + A+ER++ G+E ++  LS +ERK+ AYHE+GH LVGWML  +D +LKV+I+PRT   LGF Q     ++L + + L D++ + LGGRAAE++ F+ IT+GA+NDL+KV+K+A++ ++++GM++ +G    +  ++ E  G        PFS+  +++I+ EA  ++ SAY+  E ++  +R+KLEK+A  LL+KE+L ++ +  LIGP P+
Sbjct:  340 FRDVAGLSEAKQEVKEFVDYLKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQVPFLSMNGSEFIEMIGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMATKEGVLMLASTNRADILDKALLRPGRFDRHILIDLPTLAERKEIFEKHLSSVK--LESPPTTFSQRLARLTPGFSGADIANVCNEAALHAARNTQMEVSSKNLEYAVERLVGGTEKRSHALSLAERKVIAYHESGHALVGWMLPNSDILLKVTIVPRTSLALGFAQYTPSEQHLYSKEELFDKMCMALGGRAAENLVFNRITTGAQNDLEKVTKIAYSQIKKFGMNDTLGPIYVRDADETEGGGAMGSGGKKPFSRAMESMIDNEARHVVASAYQTTEGILTTHRDKLEKLAEALLEKETLDYDQVVQLIGPPPY 791
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Fly
Match: CG6512 (gene:FBgn0036702 transcript:FBtr0075252)

HSP 1 Score: 426.017 bits (1094), Expect = 1.173e-135
Identity = 216/446 (48.43%), Postives = 308/446 (69.06%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHS--GESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKN-LSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            FKD+AG   AKIEI EF+ +L NP ++I LGA++PKGAML GPPG GKTLL KA A EANVPF   SG +F++M  G   +++R++F  A   AP I+FIDEIDA+G+ RG  +  G S+++ TLNQLLVEMDG  +   V+V AATNRVDILDKAL+RPGRFDR I V  P ++ R  +F ++L   +  +    KN LS +++  TPG TGADI+N+CNEAA+IA+R    ++  + F+ A+ERVIAG E KT  L+  E++  A+HEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   ++ YL + + L D + + LGGR AE + F+ IT+GA++DLKK++ +A++ V  +GM+EKVG  SF V +  +   + P+S+ T  LI+ E   II  A++   +++  ++E ++K+A  LL+ E L+ +D+  L+GPRPF
Sbjct:  198 FKDVAGCEEAKIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKTSLD---KNELSRKMAALTPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERVIAGMEKKTNVLAPEEKRTVAHHEAGHAVAGWFLEHADPLLKVSIIPRGKG-LGYAQYLPKDHYLLSKEQLFDRMCMTLGGRVAEELFFNRITTGAQDDLKKITDIAYSQVVRFGMNEKVGQVSFDVGQAGDPVFSKPYSEDTAQLIDNEVRSIIKCAHEATTSLLTKHKENVQKVAERLLQNEVLSRDDMIELLGPRPF 639
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Fly
Match: CG6512 (gene:FBgn0036702 transcript:FBtr0075251)

HSP 1 Score: 426.787 bits (1096), Expect = 2.270e-134
Identity = 216/446 (48.43%), Postives = 308/446 (69.06%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHS--GESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKN-LSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            FKD+AG   AKIEI EF+ +L NP ++I LGA++PKGAML GPPG GKTLL KA A EANVPF   SG +F++M  G   +++R++F  A   AP I+FIDEIDA+G+ RG  +  G S+++ TLNQLLVEMDG  +   V+V AATNRVDILDKAL+RPGRFDR I V  P ++ R  +F ++L   +  +    KN LS +++  TPG TGADI+N+CNEAA+IA+R    ++  + F+ A+ERVIAG E KT  L+  E++  A+HEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   ++ YL + + L D + + LGGR AE + F+ IT+GA++DLKK++ +A++ V  +GM+EKVG  SF V +  +   + P+S+ T  LI+ E   II  A++   +++  ++E ++K+A  LL+ E L+ +D+  L+GPRPF
Sbjct:  327 FKDVAGCEEAKIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKTSLD---KNELSRKMAALTPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERVIAGMEKKTNVLAPEEKRTVAHHEAGHAVAGWFLEHADPLLKVSIIPRGKG-LGYAQYLPKDHYLLSKEQLFDRMCMTLGGRVAEELFFNRITTGAQDDLKKITDIAYSQVVRFGMNEKVGQVSFDVGQAGDPVFSKPYSEDTAQLIDNEVRSIIKCAHEATTSLLTKHKENVQKVAERLLQNEVLSRDDMIELLGPRPF 768
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Fly
Match: YME1L (gene:FBgn0034792 transcript:FBtr0071906)

HSP 1 Score: 327.02 bits (837), Expect = 4.851e-98
Identity = 178/441 (40.36%), Postives = 274/441 (62.13%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLI 3120
            TF+D+ G   AK E++E +++L +P KF  LG +LPKG +L+GPPG GKTLL +A+A EA VPFF+ +GP+F ++  GQ A ++R++F+ A + AP +IFIDEID++G  R         +QT+NQLL EMDG    AGVIV  ATNR D LD+AL+RPGRFD  ++V  P    RKE+ +LYL+K    I     +L D L+  T G TGAD+ N+ N+AA+ A+    +TV+ +  + A ++V+ G E K R   E    I AYHE GH +V +  K + P+ KV+I+PR   L        + +Y      L+  +  ++GGRAAE + F  D ITSGA +DLK+ + +A +MVR+WGMS+KVG  + + + +   +G+      T   ++ E  +I+  +Y++A+ +++ +  + + +A  LLK E+L  +DI+ ++
Sbjct:  298 TFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLYLTK----ILHDEIDL-DMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMGPERKARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTAYIPEKERYHVTKAQLLAMMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTIEAS-KGLGTGD-TLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAIL 731
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Zebrafish
Match: AL954648.3 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:NCBI gene;Acc:794740])

HSP 1 Score: 456.833 bits (1174), Expect = 2.121e-147
Identity = 218/451 (48.34%), Postives = 325/451 (72.06%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+  AK+E++EF+ YL NP ++++LGA++PKG++LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF + E  E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ERKE+F  +L   +        +L  RL+  TPG +GADI+NICNEAA+ A+R  +K++    F+ A+ERVIAGS  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+ITF+ +T+GA++DL+KV+++A++MV+++GM + VG  SF  +E     G  PFS+  Q  +++EA  +I  AY+  E ++  NR+KL  +A  LL++E + + DIE L+GP PFG
Sbjct:  198 VSFKDVAGMREAKMEVKEFVDYLKNPDRYLQLGAKVPKGSLLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTNMSGFSNTE--EEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERKEIFEQHLKILKLTQPADFYSL--RLAELTPGFSGADIANICNEAALHAAREGFKSIDTFSFEYAVERVIAGSVKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPRDQFLFTKEQLFERMCMALGGRASEAITFNKVTTGAQDDLRKVTRVAYSMVKQYGMVDSVGQVSFPDSENQSGIGRRPFSQGLQQQMDLEAKMLIAKAYRHTEKLLLDNRDKLILLANALLEREVVNYNDIEALLGPPPFG 644
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Zebrafish
Match: AL954648.2 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:NCBI gene;Acc:794740])

HSP 1 Score: 456.833 bits (1174), Expect = 2.121e-147
Identity = 218/451 (48.34%), Postives = 325/451 (72.06%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+  AK+E++EF+ YL NP ++++LGA++PKG++LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF + E  E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ERKE+F  +L   +        +L  RL+  TPG +GADI+NICNEAA+ A+R  +K++    F+ A+ERVIAGS  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+ITF+ +T+GA++DL+KV+++A++MV+++GM + VG  SF  +E     G  PFS+  Q  +++EA  +I  AY+  E ++  NR+KL  +A  LL++E + + DIE L+GP PFG
Sbjct:  198 VSFKDVAGMREAKMEVKEFVDYLKNPDRYLQLGAKVPKGSLLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTNMSGFSNTE--EEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERKEIFEQHLKILKLTQPADFYSL--RLAELTPGFSGADIANICNEAALHAAREGFKSIDTFSFEYAVERVIAGSVKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPRDQFLFTKEQLFERMCMALGGRASEAITFNKVTTGAQDDLRKVTRVAYSMVKQYGMVDSVGQVSFPDSENQSGIGRRPFSQGLQQQMDLEAKMLIAKAYRHTEKLLLDNRDKLILLANALLEREVVNYNDIEALLGPPPFG 644
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Zebrafish
Match: spg7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:ZFIN;Acc:ZDB-GENE-030131-5391])

HSP 1 Score: 456.447 bits (1173), Expect = 5.223e-146
Identity = 218/451 (48.34%), Postives = 325/451 (72.06%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+  AK+E++EF+ YL NP ++++LGA++PKG++LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF + E  E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ERKE+F  +L   +        +L  RL+  TPG +GADI+NICNEAA+ A+R  +K++    F+ A+ERVIAGS  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+ITF+ +T+GA++DL+KV+++A++MV+++GM + VG  SF  +E     G  PFS+  Q  +++EA  +I  AY+  E ++  NR+KL  +A  LL++E + + DIE L+GP PFG
Sbjct:  297 VSFKDVAGMREAKMEVKEFVDYLKNPDRYLQLGAKVPKGSLLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTNMSGFSNTE--EEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERKEIFEQHLKILKLTQPADFYSL--RLAELTPGFSGADIANICNEAALHAAREGFKSIDTFSFEYAVERVIAGSVKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPRDQFLFTKEQLFERMCMALGGRASEAITFNKVTTGAQDDLRKVTRVAYSMVKQYGMVDSVGQVSFPDSENQSGIGRRPFSQGLQQQMDLEAKMLIAKAYRHTEKLLLDNRDKLILLANALLEREVVNYNDIEALLGPPPFG 743
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Zebrafish
Match: afg3l2 (AFG3-like AAA ATPase 2 [Source:ZFIN;Acc:ZDB-GENE-070912-46])

HSP 1 Score: 414.846 bits (1065), Expect = 5.071e-130
Identity = 208/453 (45.92%), Postives = 303/453 (66.89%), Query Frame = 1 
Query: 1783 FRPKHETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
             R + +  FKD+AG   AK+EI EF+ +L NP ++  LGA++PKGA+L GPPG GKTLL KA A EANVPF   +G +F++M  G   A++R++F  A  +AP I+FIDEIDA+G+ RG     G+S+++ TLNQLLVEMDG  +   V+V A TNR DILD AL+RPGRFDR I +  P ++ R  +F ++L   +   +   + L+ +++  TPG +GADI+N+CNEAA+IA+R     +  + F+ A+ERVI G E KT+ L   E+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL   + L+D + + LGGR +E I F  IT+GA++DLKKV++ A+  + ++GM+EKVG  SF +  Q E     P+S+ T  LI+ E   +I +AY++ + ++   + ++EK+A+ LL+KE L   D+  L+G RPF
Sbjct:  294 LRDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDLFVLARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTATNVVVLAGTNRPDILDPALMRPGRFDRQIYIGPPDIKGRASIFKVHLRPLKLEAELDKEALARKMAALTPGFSGADIANVCNEAALIAARHLSDAINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWFLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLKKVTQSAYAQIVQFGMNEKVGQVSFDLPRQGELVLEKPYSEATARLIDTEVRNLISTAYERTQQLLSDKKPEVEKVALRLLEKEVLDKNDMVELLGKRPF 745
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Zebrafish
Match: si:ch1073-174d20.2 (si:ch1073-174d20.2 [Source:ZFIN;Acc:ZDB-GENE-121214-51])

HSP 1 Score: 412.149 bits (1058), Expect = 1.291e-129
Identity = 208/448 (46.43%), Postives = 299/448 (66.74%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            E  FKD+AG   AK+EI EF+ +L NP ++  LGA++PKGA+L GPPG GKTLL KA A EANVPF   +G +F++M  G   A++R++F  A  +AP I+FIDEIDA+GK RG     G S+++ TLNQLLVEMDG  S   V+V A TNR D+LD AL+RPGRFDR I +  P ++ R  +F ++L   +         ++ +++  TPG TGADI+N+CNEAA+IA+R   ++V+ + F+ A++RVI G E KT+ L  +E+K  AYHEAGH +VGW L++ADP+LKVSIIPR  G LG+ Q   + +YL   + L D + ++LGGR AE + F+ IT+GA +DLKKV++ A+  + ++GMSE+VG  SF +  Q E     P+S+ T  LI+ E   ++  AY++   ++   RE+++ +   LL+KE L   D+  L+G RPF
Sbjct:  256 EVKFKDVAGCEEAKVEIMEFVNFLKNPQQYQDLGAKIPKGAVLSGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDMFALARKNAPCILFIDEIDAVGKKRGGGNFGGNSEQENTLNQLLVEMDGFNSSTNVVVLAGTNRPDVLDPALMRPGRFDRQIYLGPPDIKGRASIFKVHLRPLKLDPSVDRDAIARKMAAATPGFTGADIANVCNEAALIAARYLNESVSVKHFEQAIDRVIGGLEKKTQVLQPTEKKTVAYHEAGHAVVGWFLQHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTREQLFDRMCMMLGGRVAEQVFFNKITTGAHDDLKKVTQSAYAQIVQFGMSERVGQVSFDLPRQGETVLEKPYSEATAELIDEEVRDLVDRAYRRTLELVTEKREQVDMVGKRLLEKEVLDKADMLELLGARPF 702
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Xenopus
Match: tspan31 (tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512])

HSP 1 Score: 461.07 bits (1185), Expect = 9.685e-149
Identity = 214/448 (47.77%), Postives = 325/448 (72.54%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGE---SDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            +FKD+AG+H AK+E++EF+ YL +P ++++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R  +      ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ER+E+F  +L   +    GS    S RL+  TPG +GADI+NICNEAA+ A+R  Y+++    F+ A+ERVIAG+  K++ +S+ ER++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   + +YL   + L++ + + LGGR +E+ITF+ +T+GA++DL+KV+++A+ MV+++GM   +G  SF  +E     G  PFS+  Q +++ EA  ++ +AY++ E ++  NR+KL  +   LL++E + ++DIE LIGP PFG
Sbjct:  209 SFKDVAGMHEAKLEVKEFVDYLKSPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARTRAPCIVYIDEIDAVGKKRSTNMSSFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKSLKLTQPGSF--YSQRLAELTPGFSGADIANICNEAALHAAREGYQSIDTFNFEYAVERVIAGTAKKSKIMSKEERRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLYTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLRKVTRIAYAMVKQYGMVPSIGQVSFPDSESTPGIGRRPFSQGLQEMMDREAQLLVSTAYRRTEKLLLDNRDKLILLTNALLEREVINYDDIEHLIGPPPFG 654
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Xenopus
Match: tspan31 (tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512])

HSP 1 Score: 460.685 bits (1184), Expect = 4.070e-148
Identity = 214/448 (47.77%), Postives = 325/448 (72.54%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGE---SDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            +FKD+AG+H AK+E++EF+ YL +P ++++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R  +      ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ER+E+F  +L   +    GS    S RL+  TPG +GADI+NICNEAA+ A+R  Y+++    F+ A+ERVIAG+  K++ +S+ ER++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   + +YL   + L++ + + LGGR +E+ITF+ +T+GA++DL+KV+++A+ MV+++GM   +G  SF  +E     G  PFS+  Q +++ EA  ++ +AY++ E ++  NR+KL  +   LL++E + ++DIE LIGP PFG
Sbjct:  238 SFKDVAGMHEAKLEVKEFVDYLKSPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARTRAPCIVYIDEIDAVGKKRSTNMSSFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKSLKLTQPGSF--YSQRLAELTPGFSGADIANICNEAALHAAREGYQSIDTFNFEYAVERVIAGTAKKSKIMSKEERRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLYTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLRKVTRIAYAMVKQYGMVPSIGQVSFPDSESTPGIGRRPFSQGLQEMMDREAQLLVSTAYRRTEKLLLDNRDKLILLTNALLEREVINYDDIEHLIGPPPFG 683
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Xenopus
Match: tspan31 (tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512])

HSP 1 Score: 460.685 bits (1184), Expect = 4.148e-148
Identity = 214/448 (47.77%), Postives = 325/448 (72.54%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGE---SDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            +FKD+AG+H AK+E++EF+ YL +P ++++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R  +      ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ER+E+F  +L   +    GS    S RL+  TPG +GADI+NICNEAA+ A+R  Y+++    F+ A+ERVIAG+  K++ +S+ ER++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   + +YL   + L++ + + LGGR +E+ITF+ +T+GA++DL+KV+++A+ MV+++GM   +G  SF  +E     G  PFS+  Q +++ EA  ++ +AY++ E ++  NR+KL  +   LL++E + ++DIE LIGP PFG
Sbjct:  239 SFKDVAGMHEAKLEVKEFVDYLKSPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARTRAPCIVYIDEIDAVGKKRSTNMSSFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKSLKLTQPGSF--YSQRLAELTPGFSGADIANICNEAALHAAREGYQSIDTFNFEYAVERVIAGTAKKSKIMSKEERRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLYTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLRKVTRIAYAMVKQYGMVPSIGQVSFPDSESTPGIGRRPFSQGLQEMMDREAQLLVSTAYRRTEKLLLDNRDKLILLTNALLEREVINYDDIEHLIGPPPFG 684
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Xenopus
Match: tspan31 (tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512])

HSP 1 Score: 460.299 bits (1183), Expect = 1.271e-147
Identity = 214/448 (47.77%), Postives = 325/448 (72.54%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGE---SDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            +FKD+AG+H AK+E++EF+ YL +P ++++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R  +      ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ER+E+F  +L   +    GS    S RL+  TPG +GADI+NICNEAA+ A+R  Y+++    F+ A+ERVIAG+  K++ +S+ ER++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   + +YL   + L++ + + LGGR +E+ITF+ +T+GA++DL+KV+++A+ MV+++GM   +G  SF  +E     G  PFS+  Q +++ EA  ++ +AY++ E ++  NR+KL  +   LL++E + ++DIE LIGP PFG
Sbjct:  269 SFKDVAGMHEAKLEVKEFVDYLKSPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARTRAPCIVYIDEIDAVGKKRSTNMSSFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKSLKLTQPGSF--YSQRLAELTPGFSGADIANICNEAALHAAREGYQSIDTFNFEYAVERVIAGTAKKSKIMSKEERRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLYTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLRKVTRIAYAMVKQYGMVPSIGQVSFPDSESTPGIGRRPFSQGLQEMMDREAQLLVSTAYRRTEKLLLDNRDKLILLTNALLEREVINYDDIEHLIGPPPFG 714
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Xenopus
Match: tspan31 (tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512])

HSP 1 Score: 460.685 bits (1184), Expect = 1.383e-147
Identity = 214/448 (47.77%), Postives = 325/448 (72.54%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGE---SDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            +FKD+AG+H AK+E++EF+ YL +P ++++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R  +      ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ER+E+F  +L   +    GS    S RL+  TPG +GADI+NICNEAA+ A+R  Y+++    F+ A+ERVIAG+  K++ +S+ ER++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   + +YL   + L++ + + LGGR +E+ITF+ +T+GA++DL+KV+++A+ MV+++GM   +G  SF  +E     G  PFS+  Q +++ EA  ++ +AY++ E ++  NR+KL  +   LL++E + ++DIE LIGP PFG
Sbjct:  280 SFKDVAGMHEAKLEVKEFVDYLKSPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARTRAPCIVYIDEIDAVGKKRSTNMSSFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKSLKLTQPGSF--YSQRLAELTPGFSGADIANICNEAALHAAREGYQSIDTFNFEYAVERVIAGTAKKSKIMSKEERRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLYTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLRKVTRIAYAMVKQYGMVPSIGQVSFPDSESTPGIGRRPFSQGLQEMMDREAQLLVSTAYRRTEKLLLDNRDKLILLTNALLEREVINYDDIEHLIGPPPFG 725
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Mouse
Match: Spg7 (SPG7, paraplegin matrix AAA peptidase subunit [Source:MGI Symbol;Acc:MGI:2385906])

HSP 1 Score: 459.144 bits (1180), Expect = 2.466e-148
Identity = 219/457 (47.92%), Postives = 329/457 (71.99%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQG-----SIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSF-QVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +F+D+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR D+LD AL+RPGR DRH+ +D P L+ER+E+F       +QH++G          S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERVIAG+  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF+Q   +++YL   + L + + + LGGRAAE+I+F  +TSGA++DL+KV+++A++MV+++GM+  +G  SF +  E     G  PFS+  Q +++ EA  ++  AY+  E V+  N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  201 VSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIF-------EQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLMGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 648
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Mouse
Match: Spg7 (SPG7, paraplegin matrix AAA peptidase subunit [Source:MGI Symbol;Acc:MGI:2385906])

HSP 1 Score: 458.373 bits (1178), Expect = 8.885e-147
Identity = 218/457 (47.70%), Postives = 329/457 (71.99%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQG-----SIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHS-GNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +F+D+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR D+LD AL+RPGR DRH+ +D P L+ER+E+F       +QH++G          S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERVIAG+  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF+Q   +++YL   + L + + + LGGRAAE+I+F  +TSGA++DL+KV+++A++MV+++GM+  +G  SF   ++     G  PFS+  Q +++ EA  ++  AY+  E V+  N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  306 VSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIF-------EQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLMGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 753
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Mouse
Match: Afg3l1 (AFG3-like AAA ATPase 1 [Source:MGI Symbol;Acc:MGI:1928277])

HSP 1 Score: 417.542 bits (1072), Expect = 3.783e-131
Identity = 215/445 (48.31%), Postives = 294/445 (66.07%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKT--RGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F D+AG   AK+EI EF+ +L NP ++  LGA++PKGAML GPPG GKTLL KA A EANVPF   +G +F++M  G   A++R++F  A   AP I+FIDEIDAIG+   RG   G+S+++ TLNQ+LVEMDG  S   V+V A TNR DILD AL RPGRFDR I +  P ++ R  +F ++L   +     S   LS +L+  TPG TGADISN+CNEAA+IA+R    +V    F+ A+ERVI G E KT+ L  SE+   AYHEAGH +VGW L++ADP+LKVSIIPR  G LG+ Q   + ++L   + L D + ++LGGR AE + F  IT+GA++DL+KV++ A+  + ++GMSEK+G  SF    Q E     P+S+ T  LI+ E   ++ SAY +   ++   RE++EK+   LL+KE L   D+  L+GPRPF
Sbjct:  299 FADVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDMFAMARKHAPCILFIDEIDAIGRKRGRGHLGGQSEQENTLNQMLVEMDGFNSSTNVVVLAGTNRPDILDPALTRPGRFDRQIYIGPPDIKGRSSIFKVHLRPLKLDGSLSKDALSRKLAALTPGFTGADISNVCNEAALIAARHLSPSVQERHFEQAIERVIGGLEKKTQVLQPSEKTTVAYHEAGHAVVGWFLEHADPLLKVSIIPRGKG-LGYAQYLPREQFLYTREQLFDRMCMMLGGRVAEQLFFGQITTGAQDDLRKVTQSAYAQIVQFGMSEKLGQVSFDFPRQGETMVEKPYSEATAQLIDEEVRCLVRSAYNRTLELLTQCREQVEKVGRRLLEKEVLEKADMIELLGPRPF 742
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Mouse
Match: Afg3l2 (AFG3-like AAA ATPase 2 [Source:MGI Symbol;Acc:MGI:1916847])

HSP 1 Score: 408.297 bits (1048), Expect = 2.044e-127
Identity = 205/448 (45.76%), Postives = 297/448 (66.29%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            +  FKD+AG   AK+EI EF+ +L NP ++  LGA++PKGA+L GPPG GKTLL KA A EANVPF   SG +F++M  G   A++R++F  A  +AP I+FIDEIDA+G+ RG     G+S+++ TLNQLLVEMDG  +   V++ A TNR DILD AL+RPGRFDR I +  P ++ R  +F ++L   +         L+ +L+  TPG +GAD++N+CNEAA+IA+R     +  + F+ A+ERVI G E KT+ L   E+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL   + L+D + + LGGR +E I F  IT+GA++DL+KV++ A+  + ++GM+EKVG  SF +  Q +     P+S+ T  +I+ E   +I  AY++   ++   +  +EK+A+ LL+KE L   D+  L+GPRPF
Sbjct:  303 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISDAYRRTVALLTEKKADVEKVALLLLEKEVLDKNDMVQLLGPRPF 749
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Mouse
Match: Spg7 (SPG7, paraplegin matrix AAA peptidase subunit [Source:MGI Symbol;Acc:MGI:2385906])

HSP 1 Score: 399.823 bits (1026), Expect = 5.954e-125
Identity = 197/457 (43.11%), Postives = 301/457 (65.86%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQG-----SIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHS-GNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +F+D+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR D+LD AL+RPGR DRH+ +D P L+ER+E+F       +QH++G          S RL+  TPG +                                     G+  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF+Q   +++YL   + L + + + LGGRAAE+I+F  +TSGA++DL+KV+++A++MV+++GM+  +G  SF   ++     G  PFS+  Q +++ EA  ++  AY+  E V+  N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  306 VSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIF-------EQHLKGLKLTQPSSFYSQRLAELTPGFS-------------------------------------GTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLMGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 716
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. UniProt/SwissProt
Match: sp|Q9UQ90|SPG7_HUMAN (Paraplegin OS=Homo sapiens OX=9606 GN=SPG7 PE=1 SV=2)

HSP 1 Score: 459.529 bits (1181), Expect = 3.683e-146
Identity = 219/452 (48.45%), Postives = 331/452 (73.23%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHS-GNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRH+ +D P L+ER+E+F  +L K+ +  Q S    S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERV+AG+  K++ LS+ E+K+ A+HE+GH LVGWML++ + ++KVSI PRT   LGF Q   ++++L   + L + + + LGGRA+E+++F+ +TSGA++DL+KV+++A++MV+++GM+  +G  SF   ++     G  PFS+  Q +++ EA  ++  AY+  E V++ N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  306 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHL-KSLKLTQSST-FYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 753
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. UniProt/SwissProt
Match: sp|Q3ULF4|SPG7_MOUSE (Paraplegin OS=Mus musculus OX=10090 GN=Spg7 PE=1 SV=1)

HSP 1 Score: 458.373 bits (1178), Expect = 6.215e-146
Identity = 218/457 (47.70%), Postives = 329/457 (71.99%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQG-----SIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHS-GNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +F+D+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR D+LD AL+RPGR DRH+ +D P L+ER+E+F       +QH++G          S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERVIAG+  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF+Q   +++YL   + L + + + LGGRAAE+I+F  +TSGA++DL+KV+++A++MV+++GM+  +G  SF   ++     G  PFS+  Q +++ EA  ++  AY+  E V+  N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  306 VSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIF-------EQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLMGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 753
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. UniProt/SwissProt
Match: sp|Q7TT47|SPG7_RAT (Paraplegin OS=Rattus norvegicus OX=10116 GN=Spg7 PE=2 SV=2)

HSP 1 Score: 458.373 bits (1178), Expect = 7.679e-146
Identity = 219/457 (47.92%), Postives = 329/457 (71.99%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQG-----SIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSF-QVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +F+D+AG+H AK+E++EF+ YL +P +F++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +GP+F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR D+LD AL+RPGR DRH+ +D P L+ER+E+F       +QH++G          S RL+  TPG +GADI+NICNEAA+ A+R  + +V    F+ A+ERVIAG+  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF+Q   +++YL   + L + + + LGGRAAE+I+F  +TSGA++DL+KV+++A++MV+++GM+  +G  SF +  E     G  PFS+  Q +++ EA  ++  AY+  E V+  N +KL+ +A  LL+KE + +EDIE LIGP P G
Sbjct:  306 VSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSN--TEEEQTLNQLLVEMDGMGTADHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIF-------EQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLVGIGRRPFSQGLQQMMDHEARLLVARAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHG 753
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. UniProt/SwissProt
Match: sp|D0MGU8|FTSH_RHOM4 (ATP-dependent zinc metalloprotease FtsH OS=Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) OX=518766 GN=ftsH PE=3 SV=1)

HSP 1 Score: 445.662 bits (1145), Expect = 4.296e-142
Identity = 222/453 (49.01%), Postives = 316/453 (69.76%), Query Frame = 1 
Query: 1795 HETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRG--FHSGESDE-DQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNF--PFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            H  TFKD+AGL  AK E+ E +++L NP KF +LG +LPKG +L+GPPG GKTLL KA+A EA VPFF  SG DF++M  G  AA++R++FR+A   AP IIFIDEIDAIG++RG     G +DE + TLNQLLVEMDG  +  GVI+ AATNR D+LD AL+RPGRFDR IL+D P   ER E+F ++    +  I G   +L + L+ QTPG  GA+I+N+CNEAA++A+R   + V  E F+ A++RVIAG E K + +S  ER+I AYHEAGH +VGW L+Y DP++KVSI+PR +  LG+ Q   + +YL   + L+D +++ +GGR AE + F  I++GA+NDL++++++A+ MV ++GMSE+VG+ SF ++ Q      F  P+S+ T  LI+ E  +II    ++A  +++  R+KLE +A  LL+KE L   D+  ++GPRP+G
Sbjct:  206 HRVTFKDVAGLDEAKEEVAEIVEFLKNPKKFTRLGGKLPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAARVRDLFRQAKEKAPCIIFIDEIDAIGRSRGRGIMMGANDERENTLNQLLVEMDGFNTDKGVIIMAATNRPDVLDPALLRPGRFDRQILIDKPDRRERLEIFKVH---TRDLILGDDVDL-EVLAGQTPGFAGAEIANVCNEAALLAARKGKEAVEMEDFEQAIDRVIAGLEKKNKIISPEEREIVAYHEAGHAIVGWFLRYTDPVVKVSIVPRGLAALGYAQYLPEERYLYTKEALLDRMTMAIGGRVAEELVFGRISTGAQNDLERITRMAYAMVVDYGMSERVGYVSFNLSGQYGEQAFFDKPYSEETARLIDEEVRRIINEVRERARRILEEKRDKLEALARRLLEKEVLGPRDLVEILGPRPYG 654
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. UniProt/SwissProt
Match: sp|P40341|YTA12_YEAST (Mitochondrial respiratory chain complexes assembly protein YTA12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YTA12 PE=1 SV=2)

HSP 1 Score: 437.187 bits (1123), Expect = 2.706e-137
Identity = 226/446 (50.67%), Postives = 305/446 (68.39%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR--GFHSGESDE-DQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            FKD+AG   AK EI EF+ +L  PS++ K+GA++P+GA+L GPPG GKTLL KA A EA VPF++ SG +F++M  G  AA++R++F+ A  +APSI+FIDEIDAIGK R  G  SG +DE + TLNQ+LVEMDG      V+V A TNR DILDKAL+RPGRFDRHI +D P LE RK +F ++L  +   + G I +L +RL+  TPG +GADI+N+CNEAA+IA+R D   V    F+ A+ERVI G E K++ LS  E+K+ AYHEAGH + GW LKYADP+LKVSIIPR  G LG+ Q    + +L     L D +++ LGGR +E + F  +TSGA +D KKV+ +A  MV E GMS+K+G  ++Q  ++D+     PFS  T  +I+ E  +I+   + +   ++K   E +EKIA  LLKKE LT ED+  L+G RPF
Sbjct:  347 FKDVAGCDEAKEEIMEFVSFLKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFYFVSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDEIDAIGKARQKGNFSGANDERENTLNQMLVEMDGFTPADHVVVLAGTNRPDILDKALLRPGRFDRHINIDKPELEGRKAIFAVHL--HHLKLAGEIFDLKNRLAALTPGFSGADIANVCNEAALIAARSDEDAVKLNHFEQAIERVIGGVERKSKLLSPEEKKVVAYHEAGHAVCGWYLKYADPLLKVSIIPRGQGALGYAQYLPGDIFLLTEQQLKDRMTMSLGGRVSEELHFPSVTSGASDDFKKVTSMATAMVTELGMSDKIGWVNYQ--KRDDSDLTKPFSDETGDIIDSEVYRIVQECHDRCTKLLKEKAEDVEKIAQVLLKKEVLTREDMIDLLGKRPF 788
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. TrEMBL
Match: T1G263 (AAA domain-containing protein OS=Helobdella robusta OX=6412 GN=20215161 PE=4 SV=1)

HSP 1 Score: 480.715 bits (1236), Expect = 1.740e-155
Identity = 232/450 (51.56%), Postives = 331/450 (73.56%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRG---FHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNF-PFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR 3141
            TF+D+AGLH AKIEI EF+ YL NP  +  LGA++P+GA+LLGPPGCGKTLL KA+A+EA VPF   +G +F++M GG  AA++R++F++A S +P I++IDEIDAIG+ R    +  G S+E+ TLNQLLVEMDG+ +  GVIV  +TNR ++LDKAL+R GRFDRHIL+D+P L+ER E+F +YL   +  ++   +  S+ L+  +PGM+GADI+NICNEAA+ A+R+ +K V    FD A+ERV AG   K+R LSE E+K+ +YHEAGH LVGW+L++ + +LKVSIIPRT  +LGF     Q+++L + + L  ++S+LLGGR AES+TF+ +TSGAE+DLKKV+K+A++ VR  GM+E+VG  SF  +       +  PFSK T  +I+ EA  ++   YK  E ++  N+EKL+++A  LL+KE+L++ D+E L+GP PFG+
Sbjct:   14 TFQDVAGLHEAKIEIMEFVDYLKNPKSYQSLGAKIPRGALLLGPPGCGKTLLAKAVATEAKVPFLAMAGSEFVEMLGGLGAARVRDLFKEARSRSPCIVYIDEIDAIGRKRSGDNWSPGSSEEEHTLNQLLVEMDGIGTKEGVIVLGSTNRAEVLDKALLRAGRFDRHILIDFPTLKERLEIFEIYLKTLK--LKQPPRAYSENLAQMSPGMSGADIANICNEAALHAARLGHKNVDFSDFDYAVERVTAGVAKKSRVLSELEKKVVSYHEAGHALVGWLLEHTNCLLKVSIIPRTNHVLGFAHYIPQDRHLFSSEALFQQMSLLLGGRVAESLTFNSVTSGAEDDLKKVTKMAYDQVRVMGMNERVGLVSFPTSSSSSSEYSLKPFSKETARMIDHEARLLVAKVYKFTEKLLTENKEKLKRVAEALLEKETLSYSDMEQLVGPPPFGK 461
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. TrEMBL
Match: A0A0B7A7D2 (AAA domain-containing protein OS=Arion vulgaris OX=1028688 GN=ORF101974 PE=3 SV=1)

HSP 1 Score: 484.952 bits (1247), Expect = 4.038e-153
Identity = 232/448 (51.79%), Postives = 328/448 (73.21%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQ-TLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR 3141
             TFKD+AGL  AKIE+ EF+ YL NP +F+ LGA+ P+GA+LLGPPGCGKTLL +ALA+EA VPF   +G +F++M GG  AA++R +F++A + AP II++DEIDAIG++RG  +    ED+ TLNQLLVEMDG+ +  GVI+ AATNR DILDKAL+RPGRFDRHI++D P L ER+E+F +YLSK +     S+   +  LS  TPGM+GADISN+CNEAA+ A+R     V  E F+ A+ER IAG+E +TR L+ SE+K+ AYHE+GH LVGWMLKY D +L++SI+PRT  +LGF Q    ++ L + D L + + + LGGRAAES+ F+++++GA +DLK+V+K+A++ +  +GM+ ++GH SF   + +E SG  P+S+   A I+ EA  ++  A+   ++V++ ++EKL K+A  LL+KE L + DIE LIGP  FG+
Sbjct:  348 VTFKDVAGLREAKIEVMEFVDYLTNPQRFMSLGAKTPRGALLLGPPGCGKTLLARALATEAKVPFLAMAGSEFVEMIGGVGAARIRSLFKEARNKAPCIIYVDEIDAIGRSRGGSASVGGEDEHTLNQLLVEMDGIGTQEGVIMLAATNRADILDKALLRPGRFDRHIMIDLPTLIEREEIFNVYLSKLKLSQPTSV--YAKPLSKLTPGMSGADISNVCNEAAIHAARFQKPLVEREDFEYAVERAIAGTEKRTRLLAPSEKKVVAYHESGHALVGWMLKYTDALLRISIVPRTNSVLGFAQYLPSDQKLYSQDELFERMCMALGGRAAESLIFNHVSTGAHDDLKRVTKMAYDQICSFGMNARIGHLSF--PKDEESSGTKPYSQKLAAAIDEEARMLVTRAFLHTQSVLQEHKEKLHKLATTLLEKEVLNYNDIENLIGPPLFGK 791
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. TrEMBL
Match: A0A0N4UJ61 (AAA domain-containing protein OS=Dracunculus medinensis OX=318479 GN=DME_LOCUS10111 PE=4 SV=1)

HSP 1 Score: 477.248 bits (1227), Expect = 1.034e-152
Identity = 240/452 (53.10%), Postives = 322/452 (71.24%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRG-----FHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNF---PFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            FKD+AGLH AK+EI EF+ YL NP+K+  LGA+LPKGA+L GPPGCGKTLL KALA E++ PF   +G +F+++ GG  A+++R +F++A + AP II+IDEIDAIG+ R         G S+E+QTLNQLLVEMDGM+S   VIV A+TNR DILDKAL+RPGRFDRHIL+D+P   ER+E+F LYL K +  +       S RL+  TPGMTGADISN+ NEAA+ A+    K VT E  D AL+R++ GSE +   L + ER++ AYHEAGH +VGW+L+Y D +LK+SI+PRT  LLGF Q    ++ + + D L D + +LLGGRAAE++ F  IT+GAE+DLKKV+K A+  +  +GM+EKVG  SF  T  D +  NF   PFS   Q L++ EA+Q++  AY   E ++K N+E LEK+A +LL+KE L +E+I+ LIGP  +G
Sbjct:  158 FKDVAGLHEAKVEISEFVDYLKNPTKYSNLGAKLPKGALLTGPPGCGKTLLAKALAVESSAPFIAVNGTEFVEIIGGLGASRIRNLFKEAKARAPCIIYIDEIDAIGRKRSGNQGRLDGGSSEEEQTLNQLLVEMDGMDSTKSVIVLASTNRADILDKALLRPGRFDRHILIDHPTASERQEIFNLYLKKIR--LDNDPIYYSKRLAQMTPGMTGADISNVVNEAAIRAATTSKKIVTVEELDYALQRILGGSEKRNSALLKEEREVVAYHEAGHAIVGWLLEYTDALLKISIVPRTNALLGFAQYSPSDRKILSKDELFDRMCMLLGGRAAENVIFGKITTGAEDDLKKVTKSAYAQIMLYGMNEKVGPLSFAST--DANILNFYEKPFSSRLQKLMDEEASQLVSRAYFFTEQLLKNNKEMLEKLAKKLLEKEVLNYEEIKELIGPPKYG 605
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. TrEMBL
Match: A0A443SN24 (Paraplegin-like protein OS=Leptotrombidium deliense OX=299467 GN=B4U80_11580 PE=3 SV=1)

HSP 1 Score: 478.789 bits (1231), Expect = 3.350e-152
Identity = 230/456 (50.44%), Postives = 330/456 (72.37%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR--GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQG-----SIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHS----GNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR 3141
            F+D+AGL  AK+E+ EF+ YL N  K+ KLGA++PKGA+LLGPPGCGKTLL KA+A+EANVPF   +GP+F++M GG  AA++R++F++A   AP I++IDEIDAIG+ R  G  +   +E+QTLNQLLVEMDGM     VI+ A+TNR D+LDKAL+RPGRFDRHIL+DYP L+ERKE+F       +QH++G        N S R+S  TPG +GADI+N+CNEAA+ A++   K +++   + A+ERVI G+E K+  +S+ E+K+ AYHE GH LVGW+LK+ D +LKV+I+PRT  +LGF Q    ++ L + D L +++ + LGGR +ES+TF+ I+SGA +DL+KV+K+A+  +R++GM   VGH SF   ++ E +    G  P+SK    +++++A  +I +AYKK E ++  N++KL+ +A ELLK E+L + DIE LIGP PFG+
Sbjct:  216 FEDVAGLREAKVEVMEFVDYLKNQEKYSKLGAKVPKGALLLGPPGCGKTLLAKAVATEANVPFLAMAGPEFVEMIGGLGAARVRDLFKEAKKRAPCIVYIDEIDAIGRKRSSGATNMSGEEEQTLNQLLVEMDGMAERQNVILLASTNRADVLDKALLRPGRFDRHILIDYPTLQERKEIF-------EQHLKGLKLEKKPANYSARMSQLTPGFSGADIANVCNEAALNAAKHQKKQISDVDLEYAVERVIGGTEKKSHAMSQEEKKVVAYHECGHALVGWLLKHTDALLKVTIVPRTSNVLGFAQYLPSDQKLYSKDELFEKMCMALGGRVSESLTFNRISSGAVDDLQKVTKMAYAQIRQYGMDPVVGHLSFPSEQEMEANKMIVGKRPYSKKLTNIMDIQARNLIANAYKKTETILLENKDKLKTLAEELLKSETLNYSDIEKLIGPPPFGK 664
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. TrEMBL
Match: R7T3G8 (AAA domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_150049 PE=3 SV=1)

HSP 1 Score: 473.781 bits (1218), Expect = 2.044e-151
Identity = 232/450 (51.56%), Postives = 322/450 (71.56%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHS---GESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNF-PFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR 3141
            TFKD+AGLH AK+EI EF+ YL  P KF  +GAR+PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G DF++M GG  A+++R++F+ A  ++P I++IDEIDAIG++RG  +   G  + +QTLNQLLVEMDGM S  GVI+ A+TNR DILDKAL+RPGRFDRHIL+D P L+ER+E F LYL K +        N  + L+  +PGM+GADI+NICNEAA+ A+R   K +    FD A+ERVIAG   K+  LS+ E+KI AYHEAGH LVGW+L++ D +LKV+I+PRT   LGF Q   +   L + D L D++ + +GGR AES+TF+ ++ GA++DL +++K+A+  +RE GM++KVG  S+ V    E+  N  P+S Y   +I+ EA  +I  +YK  E +++ N+EKL  I+  LL+KE L+++D+E L+GP  FG+
Sbjct:  163 TFKDVAGLHEAKVEIMEFVDYLKRPEKFKSIGARIPKGALLLGPPGCGKTLLAKAVANEAEVPFLAMAGSDFVEMIGGLGASRVRDLFKDARENSPCIVYIDEIDAIGRSRGGQNVAEGSGEGEQTLNQLLVEMDGMGSTQGVIMLASTNRADILDKALLRPGRFDRHILIDLPTLQERRETFDLYLKKLKT--ASPAVNYIENLAQLSPGMSGADIANICNEAALYAARHKKKAIDVSDFDYAVERVIAGVAKKSTVLSQMEKKILAYHEAGHALVGWLLEHTDVLLKVTIVPRTSKALGFAQYMPKENVLYSKDELFDKMCMAMGGRVAESLTFNTVSQGAQDDLSRITKMAYLQIRELGMNDKVGPVSYGV----ENEANVKPYSMYLGQVIDEEARILIAKSYKATEKILRENKEKLRVISEALLEKECLSYKDMEELVGPPTFGK 606
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Cavefish
Match: spg7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:NCBI gene;Acc:103029937])

HSP 1 Score: 463.381 bits (1191), Expect = 2.571e-148
Identity = 222/451 (49.22%), Postives = 327/451 (72.51%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL NP ++++LGA++PKG++LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A S AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ERKE+F  +L   +      + +L  RL+  TPG +GADI+NICNEAA+ A+R  +K++    F+ A+ERVIAGS  K++ LS+ E+++ A+HE+GH LVGW+L++ + ++KVSI PRT   LGF Q   +++YL   + L + + + LGGRA+E+ITF+ +T+GA++DL+KV+++A+ MV+++GM   VGH SF  +E     G  PFS+  Q  ++ EA  +I  AY+K E ++  NR+KL  +A  LL++E + +EDIE L+GP P G
Sbjct:  321 VSFKDVAGMHEAKMEVKEFVDYLKNPERYLQLGAKVPKGSLLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARSRAPCIVYIDEIDAVGKKRSNNMSGFTN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERKEIFEQHLKILKLSQPADVYSL--RLAELTPGFSGADIANICNEAALHAAREGHKSIDTFNFEYAVERVIAGSVKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPKDQYLFTKEQLFERMCMALGGRASEAITFNKVTTGAQDDLRKVTRVAYAMVKQYGMVPSVGHVSFPESEVQGPLGRRPFSQGLQQKMDHEAKMLIAHAYRKTEKLLLDNRDKLAVLANALLEREVVNYEDIEALLGPPPHG 767
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Cavefish
Match: ENSAMXT00000029966.1 (pep primary_assembly:Astyanax_mexicanus-2.0:18:6368815:6385310:-1 gene:ENSAMXG00000003503.2 transcript:ENSAMXT00000029966.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 416.001 bits (1068), Expect = 1.764e-131
Identity = 210/453 (46.36%), Postives = 299/453 (66.00%), Query Frame = 1 
Query: 1783 FRPKHETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F+    T F+D+AG   AK+EI EF+ +L NP ++ +LGA++PKGA+L GPPG GKTLL KA A EA VPF   SG +F++M  G  AA++R++F  A   AP IIFIDEIDA+GK RG     G+ +++ TLNQLLVEMDG  S   V+V AATNRVD+LD AL+RPGRFDR I +  P ++ R  +F ++L   +     +   L+ +L+  TPG TGADI+N+CNEAA+IA+R     V+   F+ A+ERVI G E KT+ L  +E+   AYHEAGH +VGW L++ADP+LKVSI+PR  G LG+ Q   + ++L   + L D + ++LGGR AE + F  IT+GA++DL+KV++ A+  + ++GMSE+VG  +F   +Q       P+S+ T  LI+ E   +I  A+++   +I   R  +E++   LL+KE L   D+  L+GPRPF
Sbjct:  217 FKNNISTRFRDVAGCEEAKVEIMEFVNFLKNPKQYKELGAKIPKGAVLSGPPGTGKTLLAKATAGEAGVPFITVSGSEFLEMFVGVGAARVRDMFAMARKLAPCIIFIDEIDAVGKKRGAGNFGGQGEQENTLNQLLVEMDGFNSSTNVVVLAATNRVDVLDPALLRPGRFDRQIYIGPPDIKGRASIFKVHLRPLKLDSSLTSDALARKLAALTPGFTGADIANVCNEAALIAARHLSPAVSGVHFEQAVERVIGGLEKKTQVLQPAEKTTVAYHEAGHAVVGWFLEHADPLLKVSIVPRGKG-LGYAQYLPKEQFLFTREQLFDRMCMMLGGRVAEQVFFGRITTGAQDDLRKVTQSAYAQIVQFGMSEQVGQMAFDWPQQGGVMSEKPYSEATAQLIDQEVRSLISKAFQRTHQLITDKRGLVEQVGKRLLEKEVLEKADMMELLGPRPF 668
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Cavefish
Match: ENSAMXT00000003575.2 (pep primary_assembly:Astyanax_mexicanus-2.0:18:6368815:6385454:-1 gene:ENSAMXG00000003503.2 transcript:ENSAMXT00000003575.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 416.387 bits (1069), Expect = 2.400e-131
Identity = 210/453 (46.36%), Postives = 299/453 (66.00%), Query Frame = 1 
Query: 1783 FRPKHETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F+    T F+D+AG   AK+EI EF+ +L NP ++ +LGA++PKGA+L GPPG GKTLL KA A EA VPF   SG +F++M  G  AA++R++F  A   AP IIFIDEIDA+GK RG     G+ +++ TLNQLLVEMDG  S   V+V AATNRVD+LD AL+RPGRFDR I +  P ++ R  +F ++L   +     +   L+ +L+  TPG TGADI+N+CNEAA+IA+R     V+   F+ A+ERVI G E KT+ L  +E+   AYHEAGH +VGW L++ADP+LKVSI+PR  G LG+ Q   + ++L   + L D + ++LGGR AE + F  IT+GA++DL+KV++ A+  + ++GMSE+VG  +F   +Q       P+S+ T  LI+ E   +I  A+++   +I   R  +E++   LL+KE L   D+  L+GPRPF
Sbjct:  240 FKNNISTRFRDVAGCEEAKVEIMEFVNFLKNPKQYKELGAKIPKGAVLSGPPGTGKTLLAKATAGEAGVPFITVSGSEFLEMFVGVGAARVRDMFAMARKLAPCIIFIDEIDAVGKKRGAGNFGGQGEQENTLNQLLVEMDGFNSSTNVVVLAATNRVDVLDPALLRPGRFDRQIYIGPPDIKGRASIFKVHLRPLKLDSSLTSDALARKLAALTPGFTGADIANVCNEAALIAARHLSPAVSGVHFEQAVERVIGGLEKKTQVLQPAEKTTVAYHEAGHAVVGWFLEHADPLLKVSIVPRGKG-LGYAQYLPKEQFLFTREQLFDRMCMMLGGRVAEQVFFGRITTGAQDDLRKVTQSAYAQIVQFGMSEQVGQMAFDWPQQGGVMSEKPYSEATAQLIDQEVRSLISKAFQRTHQLITDKRGLVEQVGKRLLEKEVLEKADMMELLGPRPF 691
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Cavefish
Match: afg3l2 (AFG3-like AAA ATPase 2 [Source:ZFIN;Acc:ZDB-GENE-070912-46])

HSP 1 Score: 414.846 bits (1065), Expect = 5.275e-130
Identity = 209/453 (46.14%), Postives = 305/453 (67.33%), Query Frame = 1 
Query: 1783 FRPKHETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
             R + +  FKD+AG   AK+EI EF+ +L NP ++  LGA++PKGA+L GPPG GKTLL KA A EANVPF   +G +F++M  G   A++R++F  A  +AP I+FIDEIDA+G+ RG     G+S+++ TLNQLLVEMDG  +   V+V A TNR DILD AL+RPGRFDR I +  P ++ R  +F ++L   +   +   ++L+ +++  TPG +GADI+N+CNEAA+IA+R     +T + F+ ++ERVI G E KT+ L   E+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL   + L+D + + LGGR AE I F  IT+GA++DLKKV++ A+  + ++GM+EKVG  SF++  Q E     P+S+ T  LI+ E   +I +AY++   ++   + ++EK+A+ LL+KE L   D+  L+G RPF
Sbjct:  297 LRDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDLFVLARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTATNVVVLAGTNRPDILDPALMRPGRFDRQIYIGPPDIKGRASIFKVHLRPLKLDAELDKESLARKMAALTPGFSGADIANVCNEAALIAARHLSDAITQKHFEQSIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVAEQIFFGRITTGAQDDLKKVTQSAYAQIVQFGMNEKVGQVSFEMPRQGEMVLEKPYSEATAFLIDTEVRDLINTAYERTLKLLSEKKPEVEKVALRLLEKEVLDKNDMLELLGQRPF 748
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Cavefish
Match: afg3l2 (AFG3-like AAA ATPase 2 [Source:ZFIN;Acc:ZDB-GENE-070912-46])

HSP 1 Score: 414.075 bits (1063), Expect = 1.503e-129
Identity = 209/453 (46.14%), Postives = 305/453 (67.33%), Query Frame = 1 
Query: 1783 FRPKHETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
             R + +  FKD+AG   AK+EI EF+ +L NP ++  LGA++PKGA+L GPPG GKTLL KA A EANVPF   +G +F++M  G   A++R++F  A  +AP I+FIDEIDA+G+ RG     G+S+++ TLNQLLVEMDG  +   V+V A TNR DILD AL+RPGRFDR I +  P ++ R  +F ++L   +   +   ++L+ +++  TPG +GADI+N+CNEAA+IA+R     +T + F+ ++ERVI G E KT+ L   E+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL   + L+D + + LGGR AE I F  IT+GA++DLKKV++ A+  + ++GM+EKVG  SF++  Q E     P+S+ T  LI+ E   +I +AY++   ++   + ++EK+A+ LL+KE L   D+  L+G RPF
Sbjct:  317 LRDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDLFVLARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTATNVVVLAGTNRPDILDPALMRPGRFDRQIYIGPPDIKGRASIFKVHLRPLKLDAELDKESLARKMAALTPGFSGADIANVCNEAALIAARHLSDAITQKHFEQSIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVAEQIFFGRITTGAQDDLKKVTQSAYAQIVQFGMNEKVGQVSFEMPRQGEMVLEKPYSEATAFLIDTEVRDLINTAYERTLKLLSEKKPEVEKVALRLLEKEVLDKNDMLELLGQRPF 768
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Sea Lamprey
Match: spg7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:ZFIN;Acc:ZDB-GENE-030131-5391])

HSP 1 Score: 424.091 bits (1089), Expect = 8.718e-136
Identity = 208/430 (48.37%), Postives = 312/430 (72.56%), Query Frame = 1 
Query: 1876 PSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSG---ESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIK------NLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            P ++++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R  ++G    ++E+QTLNQLLVEMDGM     VIV A+TNR DILD AL+RPGRFDRHI +D P L+ER+E+F       +QH++ S+K      + S RL+  TPG +GADI+N+CNEAA+ A+R + K+V  + F+ A+ERVIAG+  K++ LS+ ER+I A+HE+GH + GW+L++ D +LKVSI PRT   LGF Q   +++YL + + L + + + LGGR AE+ITF+ +T+GAE+DL+KV++LA+NM+R +GM+E VGH SF   +++   G  P+S+  Q +++ EA + +  AY++ E ++  NR+KL  +A  LL+ E ++++DI  L+GP   G
Sbjct:  223 PERYLQLGAKVPKGALLLGPPGCGKTLLGKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSRNTGGFANTEEEQTLNQLLVEMDGMGPKDHVIVLASTNRADILDGALMRPGRFDRHIYIDLPTLQERREIF-------EQHLK-SLKLAQLETHYSQRLAELTPGFSGADIANVCNEAALHAARENSKSVGVDDFEYAVERVIAGTAKKSKILSKEERRIVAFHESGHAVTGWLLQHTDAVLKVSIAPRTNAALGFAQILPRDQYLHSTEELFERMCMALGGRVAEAITFNKVTNGAEDDLRKVTRLAYNMIRSFGMNEVVGHVSFPSADEEGVPGRRPYSRALQEVMDHEARKTVAQAYRRTEKLLLENRDKLILLAEALLEHEVVSYDDIVKLLGPPTHG 644
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Sea Lamprey
Match: yme1l1b (YME1-like 1b [Source:ZFIN;Acc:ZDB-GENE-070410-25])

HSP 1 Score: 305.449 bits (781), Expect = 1.033e-90
Identity = 172/444 (38.74%), Postives = 273/444 (61.49%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNEC-FDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPR--TMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLI 3120
            TF+ + G   AK E+Q+ +Q+L NP KF  LG +LPKG +L+GPPG GKTL+ +A+A EA+VPF+Y SG +F +M  G  A+++R +FR+A ++AP +IFIDE+D++G  R          QT+NQLL EMDG +   GVIV  ATN  + LD AL+RPGRFD  + V  P ++ R E+  LYLSK +  ++  +  ++  ++  T G TGA++ N+ N+AA+ A+ MD K V +    + A ++++ G+E ++  +    + I AYHE GH LV +  K A PI K +I+PR  T+G +    +D  +++ +    L+ ++ V +GGR AE I F  D IT+GA +D +  +K+A  MV  +GMSEK+G   ++  E+         S  TQ+ IE E   ++  +Y++A N++K +  + + +A  LLK E+L   +I +++
Sbjct:  290 TFEQVKGADEAKEELQDVVQFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLMARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIVIGATNFPEALDNALVRPGRFDMQVTVPRPDVKGRTEILKLYLSKVK--MESGVDPMT--IARGTVGFTGAELENLVNQAALKAA-MDGKEVVSMVELEYAKDKILMGTERRSAEIDLKNKTITAYHEGGHALVAFYTKDAMPINKATIMPRGPTLGHVSLLPED--DRWSETKAQLLAQMDVSMGGRVAEEIIFGLDNITTGASSDFETATKIASLMVTRFGMSEKLGVMIYKDQEK--------LSPETQSAIETEVRALLRDSYERARNILKAHSREHKLLAEALLKYETLDAREIRSVL 718
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Sea Lamprey
Match: si:ch1073-174d20.2 (si:ch1073-174d20.2 [Source:ZFIN;Acc:ZDB-GENE-121214-51])

HSP 1 Score: 270.396 bits (690), Expect = 3.231e-83
Identity = 135/286 (47.20%), Postives = 197/286 (68.88%), Query Frame = 1 
Query: 2050 KLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGH 2901
            ++R++F+ A  +AP I+FIDEIDA+G+ RG     G+S+++ TLNQLLVEMDG  +   V V A TNR DILD AL+RPGRFDR I V  P ++ R  +F ++L   +  +      +S +L+  TPG TGADI+N+CNEAA+IA+R   + ++ + F+ A+ERVI G E KT+ L   E++  AYHE+GH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL + + L D + + LGGR AE + F  IT+GA++DL+KV++ A+  + ++GM+EKVG 
Sbjct:    3 QVRDMFQLARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNV-VLAGTNRPDILDPALLRPGRFDRQIFVGAPDIKGRASIFKVHLKPLKTELALDKAAISRKLAALTPGFTGADIANVCNEAALIAARHLNEAISEKHFEQAIERVIGGLEKKTQVLQPEEKRTVAYHESGHAVAGWYLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYSQEQLFDRMCMTLGGRVAEQLFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQ 286
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Sea Lamprey
Match: vcp (valosin containing protein [Source:NCBI gene;Acc:327197])

HSP 1 Score: 168.703 bits (426), Expect = 2.972e-45
Identity = 94/231 (40.69%), Postives = 134/231 (58.01%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQY-LNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR--GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASR 2484
             T++DI GL + K E+QE +QY + +P KF+K G    KG +  GPPGCGKTLL KA+A+E    F    GP+ + M  G++ A +R+VF KA  ++P+++F+DE+D+I K R  G   G    D+ +NQ+L EMDGM     V +  ATNR DI+D A++RPGR D+ I +  P  + R  +    L K+       I  LS      T G +GAD+  IC  A  +A R
Sbjct:  114 VTWEDIGGLESVKRELQELVQYPVEHPEKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDVFDKARQASPTVLFLDELDSIAKARGGGVGDGGGAADRVINQILTEMDGMGVNKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRTAILKANLRKSPIAKDVDIGYLSK----TTNGFSGADLMEICQRACKLAIR 340
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Sea Lamprey
Match: psmc5 (proteasome 26S subunit, ATPase 5 [Source:ZFIN;Acc:ZDB-GENE-030131-6547])

HSP 1 Score: 166.007 bits (419), Expect = 9.362e-45
Identity = 97/257 (37.74%), Postives = 148/257 (57.59%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQY-LNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR--GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESK 2559
            ++T++ I GL     EI+E ++  + +P  F  LG   PKG +L GPPG GKTLL +A+A      F   SG + +    G+ +  +RE+F  A   APSIIF+DEID+IG +R  G   G+S+  +T+ +LL ++DG E+   + V  ATNR+DILD AL+RPGR DR I  ++P   E   L  L +   + ++   I NL  +++   PG +GA++  +C EA + A R     VT E F++A+ +V+     K
Sbjct:  149 DSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKI--EFPPPNEEARLDILKIHSRKMNLTRGI-NLR-KIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEK 401
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Yeast
Match: YTA12 (Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation [Source:SGD;Acc:S000004695])

HSP 1 Score: 437.187 bits (1123), Expect = 3.897e-139
Identity = 226/446 (50.67%), Postives = 305/446 (68.39%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR--GFHSGESDE-DQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            FKD+AG   AK EI EF+ +L  PS++ K+GA++P+GA+L GPPG GKTLL KA A EA VPF++ SG +F++M  G  AA++R++F+ A  +APSI+FIDEIDAIGK R  G  SG +DE + TLNQ+LVEMDG      V+V A TNR DILDKAL+RPGRFDRHI +D P LE RK +F ++L  +   + G I +L +RL+  TPG +GADI+N+CNEAA+IA+R D   V    F+ A+ERVI G E K++ LS  E+K+ AYHEAGH + GW LKYADP+LKVSIIPR  G LG+ Q    + +L     L D +++ LGGR +E + F  +TSGA +D KKV+ +A  MV E GMS+K+G  ++Q  ++D+     PFS  T  +I+ E  +I+   + +   ++K   E +EKIA  LLKKE LT ED+  L+G RPF
Sbjct:  347 FKDVAGCDEAKEEIMEFVSFLKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFYFVSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDEIDAIGKARQKGNFSGANDERENTLNQMLVEMDGFTPADHVVVLAGTNRPDILDKALLRPGRFDRHINIDKPELEGRKAIFAVHL--HHLKLAGEIFDLKNRLAALTPGFSGADIANVCNEAALIAARSDEDAVKLNHFEQAIERVIGGVERKSKLLSPEEKKVVAYHEAGHAVCGWYLKYADPLLKVSIIPRGQGALGYAQYLPGDIFLLTEQQLKDRMTMSLGGRVSEELHFPSVTSGASDDFKKVTSMATAMVTELGMSDKIGWVNYQ--KRDDSDLTKPFSDETGDIIDSEVYRIVQECHDRCTKLLKEKAEDVEKIAQVLLKKEVLTREDMIDLLGKRPF 788
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Yeast
Match: AFG3 (Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant [Source:SGD;Acc:S000000819])

HSP 1 Score: 433.335 bits (1113), Expect = 1.688e-138
Identity = 224/454 (49.34%), Postives = 308/454 (67.84%), Query Frame = 1 
Query: 1804 TFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRG---FHSGESDE-DQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQH--IQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNF----PFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            +FK++AG   AK EI EF+ +L NP K+ KLGA++P+GA+L GPPG GKTLL KA A EANVPF   SG +F++M  G  A+++R++F +A S APSIIFIDEIDAIGK RG      G +DE + TLNQLLVEMDG  +   V+V A TNR D+LD AL+RPGRFDRHI +D P +  R++++ ++L +      +   + NLS +L+  TPG TGADI+N CNEAA+IA+R +   +T   F+ A+ERVIAG E KTR LS+ E++  AYHEAGH + GW LKYADP+LKVSIIPR  G LG+ Q    ++YL + +     + + LGGR +E + F  +TSGA +D KKV+++A  MV   GMS K+G+ SF     D++ GNF    PFS  T   I++E   I+  A++    ++  N +K++ +A ELL+KE++T ED+  L+GPRPF
Sbjct:  286 SFKNVAGCDEAKQEIMEFVHFLKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEMFVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALGGANDEREATLNQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDPLLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERVIAGLEKKTRVLSKEEKRSVAYHEAGHAVCGWFLKYADPLLKVSIIPRGQGALGYAQYLPPDQYLISEEQFRHRMIMALGGRVSEELHFPSVTSGAHDDFKKVTQMANAMVTSLGMSPKIGYLSF-----DQNDGNFKVNKPFSNKTARTIDLEVKSIVDDAHRACTELLTKNLDKVDLVAKELLRKEAITREDMIRLLGPRPF 734
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Yeast
Match: YME1 (Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant [Source:SGD;Acc:S000006228])

HSP 1 Score: 272.322 bits (695), Expect = 7.339e-79
Identity = 159/451 (35.25%), Postives = 261/451 (57.87%), Query Frame = 1 
Query: 1792 KHETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQ--QHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDE----ISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLI 3120
            K    F D+ G   A+ E++E + +L +P+K+  LG +LPKG +L GPPG GKTLL +A A EA V FF+ SG +F ++  G  A ++R++F +A S AP+IIFIDE+DAIG  R     ++   QTLNQLLVE+DG    +G+I+  ATN  + LDKAL RPGRFD+ + VD P +  R ++   ++ K     ++  +I      ++  TPG++GA+++N+ N+AAV A + +  +V    F+ A ++++ G+E KT  L+++ RK  A+HEAGH ++      A P+ K +I+PR    LG T   FQ   +   D+   E    + V +GG+ AE + +  D  TSG  +DL+  +  A  MV ++GMS+ VG     ++E  E      +S   + + + E  +++  + ++A  ++     +L ++A  L++ E+L   +IE + 
Sbjct:  275 KTNVKFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRN-PKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTI------IARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRA-LGIT---FQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVG--PVNLSENWES-----WSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVC 707
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Yeast
Match: RPT6 (ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003016])

HSP 1 Score: 166.007 bits (419), Expect = 6.473e-45
Identity = 92/251 (36.65%), Postives = 147/251 (58.57%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQY-LNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR--GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVI 2541
            ++T+  + GL     EI+E ++  + +P  F  LG   PKG +L GPPG GKTLL +A+A   +  F   SG + +    G+ +  +RE+F  A   APSIIF+DEID+IG TR  G   G+S+  +T+ +LL ++DG E+   + +  ATNR+DILD AL+RPGR DR I    P +  R E+  ++  K       +++ ++++++    G +GAD+  +C EA + A R     VT E F++A+ +V+
Sbjct:  144 DSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGINLRKVAEKMN----GCSGADVKGVCTEAGMYALRERRIHVTQEDFELAVGKVM 390
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Yeast
Match: AFG2 (ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; releases Rlp24p from purified pre-60S particles in vitro; target of the ribosomal biosynthesis inhibitor diazaborine; may be involved in degradation of aberrant mRNAs [Source:SGD;Acc:S000004389])

HSP 1 Score: 170.244 bits (430), Expect = 4.258e-44
Identity = 101/251 (40.24%), Postives = 140/251 (55.78%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQY-LNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSK-NQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEA--AVIASRMDYKTVTNECFDIALERVIAG 2547
            + DI G    K +++E +Q  L     F +LG   PKG +L GPPGC KTL  KALA+E+ + F    GP+  +   G++   +RE+FRKA S+APSIIF DEIDA+   R   S  S  +  L  LL E+DG+E + GV++ AATNR D +D AL+RPGR DRHI V  P +  R E+      K N +     +  L+DR    T G +GA++  +C EA  A I   +D   V    F+ A + +  G
Sbjct:  515 WSDIGGQEELKTKMKEMIQLPLEASETFARLGISAPKGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESERAIREIFRKARSAAPSIIFFDEIDALSPDRD-GSSTSAANHVLTSLLNEIDGVEELKGVVIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLEILKKCTKKFNTEESGVDLHELADR----TEGYSGAEVVLLCQEAGLAAIMEDLDVAKVELRHFEKAFKGIARG 760

HSP 2 Score: 137.117 bits (344), Expect = 1.681e-33
Identity = 82/225 (36.44%), Postives = 126/225 (56.00%), Query Frame = 1 
Query: 1810 KDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSK--NQQHIQGS--IKNLSDRLSLQTPGMTGADISNICNEAAV 2472
            K+I  L +A IEI      L+ P+ F   G   P+G +L GPPG GKT+L++ +A+ +N      +GP  +    G+  A LR++F +A    PSIIFIDEID+I   R        E + +  LL  MDGM +   V+V AATNR + +D AL RPGRFD+ + +  P ++ R ++ T   S+  + +H+  S  IK ++ +    T G  GAD++ +C E+ +
Sbjct:  252 KEIESLKSA-IEIP-----LHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVANTSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEIDSIAPNRANDDSGEVESRVVATLLTLMDGMGAAGKVVVIAATNRPNSVDPALRRPGRFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIKYIASK----THGYVGADLTALCRESVM 466
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Nematostella
Match: EDO31422 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXY8])

HSP 1 Score: 449.514 bits (1155), Expect = 1.274e-145
Identity = 217/449 (48.33%), Postives = 318/449 (70.82%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFH---SGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            + FKD+AG+  AK+E+ EF+ YL +  ++ +LGA++PKGA+L+GPPG GKTLL KA+A+EA+VPF   +G DF++M  G  +A++R++F +A   AP I++IDE+DAIG++R       G ++++ TLNQLLVEMDGM ++ GVI+ A+TNR DILD AL+RPGRFDRHI +D P L ER E+F ++L K    ++ SI   + RL+  TPG +GADI+NICNEAA+ A+R++ K V  + F+ A+ERVIAG E +T  +S  ER+I AYHEAGH LVGWML++ +P+LKVSI+PRT   LG+ Q    ++ L   + L D + + LGGRAAE   F  IT+GAE+DL+KV+ +A+  +  +GM+++VG+ SF V +  E  G  P+S +   LI+ E   +I  A+   +N++  + +KL+ +A EL+KKE L ++DI +LIGP P+G
Sbjct:  174 SMFKDVAGMQEAKMEVMEFVDYLKSAGRYTQLGAKIPKGALLVGPPGTGKTLLAKAVATEADVPFLSMAGSDFVEMFAGVGSARVRDLFTRARKLAPCIVYIDEVDAIGRSRKSSRSMGGHNEQENTLNQLLVEMDGMNTLDGVIMLASTNRADILDNALLRPGRFDRHIAIDLPTLPERMEIFEVHLKKLT--LKRSIDQYTKRLAELTPGHSGADIANICNEAALHAARLNKKNVDTKNFEYAVERVIAGMEKRTHTMSPDERRIVAYHEAGHALVGWMLEHTEPLLKVSIVPRTNASLGYAQYLPSDQKLYTTEQLFDRMCMALGGRAAEGKIFRRITTGAEDDLRKVTDMAYRQIITYGMNDRVGNISFPVKKSQEF-GKKPYSDHLSHLIDEEVRLLISRAFDATDNILTKHSDKLKVLAEELIKKEVLNYDDISSLIGPCPYG 619
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Nematostella
Match: EDO40553 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S706])

HSP 1 Score: 414.461 bits (1064), Expect = 2.264e-132
Identity = 209/446 (46.86%), Postives = 304/446 (68.16%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF---HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            FKD+AG   AK+EI EF+ +L NP ++ +LGA++PKGA+L GPPG GKTLL KA+A EA VPF   SG +F++M  G   A++R++F +A  +AP IIFIDEIDA+G+ RG      G  + + TLNQLLVEMDG  S   V+V + TNR D+LD AL+RPGRFDR I +  P ++ R  +F ++L   ++++    + L+ +++  TPG TGADI+N+CNEAA+IA+R     V  + F+ A+ERVI G E KT+ L   E+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL   + L+D + + LGGR +E + F  IT+GA++DL KV+K A+  V  +GM+ K+G+ SF +  + E S + P+S+ T  LI+ +A ++I SAY +   +++ +++ +EK+A  LL+KE L  ED+  L+GPRPF
Sbjct:  145 FKDVAGCEEAKLEIMEFVNFLKNPQQYHELGAKIPKGAILSGPPGTGKTLLAKAVAGEAGVPFLSISGSEFLEMFVGVGPARVRDLFAQARKNAPCIIFIDEIDAVGRARGRGGQFGGHDERENTLNQLLVEMDGFSSSTNVVVLSGTNRPDVLDPALLRPGRFDRQIHLPAPDIKGRCSIFKVHLKPIKKNVDE--EKLARKMAALTPGFTGADIANVCNEAALIAARYLAPFVEEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWFLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTTEQLLDRMCMTLGGRVSEQLFFQKITTGAQDDLSKVTKSAYAQVVTYGMNSKLGNVSFDLPREGEPSFDKPYSEATAQLIDEQARELINSAYGRTTELLEKHKDDVEKVAKRLLEKEVLDREDMIDLLGPRPF 587
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Nematostella
Match: EDO49472 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG54])

HSP 1 Score: 312.383 bits (799), Expect = 1.102e-95
Identity = 180/449 (40.09%), Postives = 268/449 (59.69%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSD--RLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR 3141
            F+D+ G+  AK E+QE +++L NP KF +LG +LP G +L+G PG GKTLL KA+A EA VPFF+ SG +F +M  G  AA++R +F  A   AP I+F+DE+DAIG +R  H  +     TLNQLLVE+DG E   G++V  ATN  ++LDKAL+RPGRFD  I V  P +  R  +  ++L KN      +I N  D   L+  T G +GAD++N+ N+AA+ A+     +V N+  + A +++I G E K+  ++   RKI AYHE GH LV +  + + P+ K +I+PR   L   +Q   +++       L+  I V + GR AE I F  + IT+GA +D +  + LA  MV  +GMSEKVG  + QV E +        S  T+ LIE E   ++  AY++A+N+++   ++ +++A  LLK E+L  E+I  +I   P  R
Sbjct:   64 FEDVQGVDEAKEELQEVVEFLRNPEKFKRLGGKLPTGVLLIGSPGTGKTLLAKAVAGEAGVPFFFCSGSEFDEMFVGVGAARVRNLFAAAKEHAPCIVFVDELDAIGGSRVVHDHQPYSRMTLNQLLVELDGFEKSEGIVVIGATNFPEVLDKALVRPGRFDTKINVPMPDVRARLNILKVHL-KNV-----TISNEVDIEVLARGTSGFSGADLANLVNQAALKAATSGDSSVMNKHLEYAKDKIIMGPERKSAVINSENRKIVAYHEGGHALVAFYTEGSLPLHKATIMPRGQALGMVSQLPEKDELQWTKKQLLARIDVSMAGRVAEEIIFGKENITTGASSDFQAATNLAKAMVTTYGMSEKVG--TVQVKEDE------TLSPDTRLLIENEVKHLLAEAYERAKNILQSQAKEHKRLAEALLKYETLNAEEIGRVIRGEPINR 498
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Nematostella
Match: EDO39006 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBC8])

HSP 1 Score: 182.57 bits (462), Expect = 1.006e-48
Identity = 106/288 (36.81%), Postives = 162/288 (56.25%), Query Frame = 1 
Query: 1645 LNALRSATKYHDLPQTKKLEKPSQNDLYYPTILKEMKERMDGEYNNFRPKH---------ETTFKDIAGLHNAKIEIQEFLQY-LNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIA 2478
            L A + +   HD   ++ LE   Q D      L    E M   +   RP           +  + D+ G    K +++E +++ L +P  F +LG R P+G ++ GPPGC KTL+ +ALA+E+ + F    GP+      G++   +REVF KA ++APSI+F DE+DAI   R    G    D+ L QLL E+DG+E++  VI  AATNR D++DKAL+RPGR DR I V  P  + R+ +  ++L++     +GS+ +L D L  +T G +GA+I+ +C EAA+ A
Sbjct:  247 LYAFKRSLHNHDNGSSQSLE---QRDARIKRELLVSSEDMRAAFRCVRPSAMREVALEVPKVHWSDVGGNEMIKRKLKEAVEWPLKHPEAFQRLGIRPPRGILMYGPPGCSKTLIARALATESGLNFIAIKGPELFSKWVGESEKAVREVFLKARATAPSIVFFDELDAIAGQRNSTGGSDVNDRVLTQLLTELDGVETLKDVIFIAATNRPDMIDKALMRPGRVDRLIYVPLPCWDTRRHILEIHLARTP--CEGSL-DLED-LVERTEGYSGAEIAAVCREAALAA 527

HSP 2 Score: 147.132 bits (370), Expect = 6.823e-37
Identity = 90/237 (37.97%), Postives = 131/237 (55.27%), Query Frame = 1 
Query: 1792 KHETTFKDIAGLHNAKIEIQEFLQY-LNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAG---VIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDR----LSLQTPGMTGADISNICNEAAVIA 2478
            K   +F+ I GL      ++E ++  L NP  F   G   P+G +L GP G GKT++ +A+A+E  V FF  +GP+ +    G+  A+LRE+F +A + +PSI+FIDE+DA+   R     E  E + +  LL  MDGM   +    V+V AATNR D LD AL RPGRFDR I +  P + +R+++    L KN  H      +L D     L+    G  GAD++  C EA++ A
Sbjct:   21 KKGVSFQSIGGLKTQIQAVREMIEMPLTNPELFTAYGVPPPRGILLYGPSGTGKTMIARAVANETGVHFFCINGPEVLSRYYGETEARLREIFTEAQNKSPSIVFIDELDALCPRRDKVQNEF-ERRVVATLLTLMDGMHMKSTDTYVMVLAATNRPDALDPALRRPGRFDREIEIGIPSVTDRRDILVTLL-KNVPH------SLHDEDISSLAESAHGYVGADLAAACKEASLYA 249
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Nematostella
Match: EDO49524 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGH4])

HSP 1 Score: 169.859 bits (429), Expect = 8.065e-46
Identity = 96/257 (37.35%), Postives = 148/257 (57.59%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQY-LNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR--GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESK 2559
            ++T++ + GL     EI+E ++  + +P  F  LG   PKG +L GPPG GKTLL +A+A      F   SG + +    G+ A  +RE+F  A   APSIIF+DEID+IG +R  G   G+S+  +T+ +LL ++DG E+   + V  ATNR+DILD AL+RPGR DR I    P  E R+++  ++  K       ++K +++ +    PG +GA+I  +C EA + A R     VT E F++A+ +V+     K
Sbjct:  137 DSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIDQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARQDILKIHSRKMNLTRGINLKKIAELM----PGASGAEIKGVCTEAGMYALRERRVHVTQEDFEMAVTKVMQKDSEK 389
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Medaka
Match: spg7 (SPG7 matrix AAA peptidase subunit, paraplegin [Source:NCBI gene;Acc:101169593])

HSP 1 Score: 460.299 bits (1183), Expect = 3.087e-147
Identity = 220/451 (48.78%), Postives = 325/451 (72.06%), Query Frame = 1 
Query: 1801 TTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTR-----GFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
             +FKD+AG+H AK+E++EF+ YL +P ++++LGA++PKGA+LLGPPGCGKTLL KA+A+EA VPF   +G +F+++ GG  AA++R +F++A + AP I++IDEIDA+GK R     GF +  ++E+QTLNQLLVEMDGM +   VIV A+TNR DILD AL+RPGR DRHI +D P L+ERKE+F  +L   +        +L  RL+  TPG +GADI+NICNEAA+ A+R   K++    F+ A+ERVIAGS  K++ LS+ E+++ A+HE+GH LVGW+L++ + +LKVSI PRT   LGF Q   +++YL   + L + + + LGGR AE+ITF+ +T+GA++DL+KV+++A++MV+++GM + VG  SF  TE+    G  PFS+  Q  ++ EA  +I  AY+  E ++  NR+KL  +A  LL++E + ++DIE L+GP P G
Sbjct:  319 VSFKDVAGMHEAKMEVKEFVDYLKSPERYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTNMSGFSN--TEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERKEIFEQHLKMLKLTQPADFYSL--RLAELTPGFSGADIANICNEAALHAAREGLKSIDTFNFEYAVERVIAGSVKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVLKVSIAPRTNAALGFAQMLPRDQYLFTKEQLFERMCMALGGRTAEAITFNKVTTGAQDDLRKVTRVAYSMVKQYGMCDSVGQVSFPETEEQGAVGRRPFSQGLQEQMDHEAKMLIARAYRHTEKLLLDNRDKLTLLANALLEREVVNYDDIEALLGPPPHG 765
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Medaka
Match: si:ch1073-174d20.2 (AFG3-like protein 1 [Source:NCBI gene;Acc:101157690])

HSP 1 Score: 419.083 bits (1076), Expect = 3.738e-132
Identity = 212/448 (47.32%), Postives = 299/448 (66.74%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            +  FKD+AG   AK+EI EF+ +L NP +++ LGA++PKGA+L GPPG GKTLL KA A EANVPF   +G +F++M  G   A++R++F  A  +AP I+FIDEIDA+G+ RG     G+S+++ TLNQLLVEMDG  +   V+V A TNR DILD AL+RPGRFDR I +  P ++ R  +F ++L   +         L+ R++  TPG TGADI+N+CNEAA+IASR    +V  + F+ A++RVI G E KT+ L  SE+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL + + L D + ++LGGR AE + F  IT+GA++DLKKV++ A+  V ++GMS+KVG  SF +  Q E     P+S+ T  LI+ E   ++  AY+    +I+  R+ +E +   LL+KE L   D+  L+GPRPF
Sbjct:  269 DVKFKDVAGCEEAKLEIMEFVNFLKNPQQYLDLGAKIPKGAVLSGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDMFALARKNAPCILFIDEIDAVGRKRGGGNFGGQSEQENTLNQLLVEMDGFNTATNVVVLAGTNRPDILDPALMRPGRFDRQIYIGPPDIKGRASIFKVHLRPIKVEPSLDKDALARRMAAATPGFTGADIANVCNEAALIASRYLEPSVNGKHFEQAIDRVIGGLEKKTQVLQPSEKKTVAYHEAGHAVTGWFLQHADPLLKVSIIPRGKG-LGYAQYLPREQYLYSKEQLFDRMCMMLGGRVAEQVFFGRITTGAQDDLKKVTQSAYAQVVQFGMSDKVGQVSFDLPRQGETVLEKPYSEATAELIDQEVRGLVDRAYEHTLQLIQHKRDLVEMVGKRLLEKEVLVKADMLELLGPRPF 715
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Medaka
Match: afg3l2 (AFG3 like matrix AAA peptidase subunit 2 [Source:NCBI gene;Acc:101168241])

HSP 1 Score: 406.757 bits (1044), Expect = 5.801e-127
Identity = 204/448 (45.54%), Postives = 298/448 (66.52%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            +  FKD+AG   AK+EI EF+ +L NP ++  LGA++PKGA+L GPPG GKTLL KA A EANVPF   +G +F++M  G   A++R++F  A  +AP I+FIDEIDA+G+ RG     G+S+++ TLNQLLVEMDG  + + V+V A TNR DILD AL+RPGRFDR I +  P ++ R  +F ++L   +         L+ +++  TPG +GADI+N+CNEAA+IA+R     +  + F+ A+ERVI G E KT+ L   E+K  AYHEAGH + GW L++ADP+LKVSIIPR  G LG+ Q   + +YL   + L+D + + LGGR +E I F  IT+GA++DL+KV++ A+  + ++GM++KVG  SF +  Q E     P+S+ T  LI+ E   +I  AY++ + +++  + ++E +A  LL+KE L   D+  L+G RPF
Sbjct:  301 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDLFVMARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTASNVVVLAGTNRPDILDPALMRPGRFDRQIYIGPPDIKGRASIFKVHLRPLKLATDMDKDALARKMAALTPGFSGADIANVCNEAALIAARHLSDNINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWFLEHADPLLKVSIIPRGKG-LGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNQKVGQVSFDLPRQGEMVLEKPYSEATARLIDTEVRILISEAYERTKQLLQDKKGEVEMVAQRLLEKEVLDKNDMVELLGKRPF 747
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Medaka
Match: ENSORLT00000011850.2 (AFG3-like protein 1 [Source:NCBI gene;Acc:101159734])

HSP 1 Score: 389.037 bits (998), Expect = 7.851e-121
Identity = 195/445 (43.82%), Postives = 289/445 (64.94%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F+D+AG  +AK+EI E + +L +P ++  LGA+ PKGA+L GPPG GKTLL KA A E +VPF   +G +F ++  G   A++R++F KA S AP I+FIDEIDA+G+ RG   +  +S+++ TLNQLLVEMDG  S   V+V A+TNR DILD AL+RPGRFDRHI +  P L+ R  +F ++L   +      ++ L   L+  TP  TGA+I+ +CNEAA+IA+R   + +  E F++A+ER+I G E K + L   E+   AYH+AGH + GW LK+ADPI K+SI+PR   L   +Q   + ++L + D L D + ++LGGR +E I F  ITSGA +DL++ ++LA+  + ++GM++ VG  SF   +Q       PF + T  LI++E   +I +A+ +   ++   +E +EK+A  LL+KE L   D+  L+GPRPF
Sbjct:  280 FEDVAGCEDAKLEIMELVNFLKHPHQYRDLGAKTPKGALLTGPPGTGKTLLAKATAGEVDVPFISVNGSEFQEVFVGVGPARIRDLFVKAHSMAPCILFIDEIDAVGRKRGSGNYMNQSEQENTLNQLLVEMDGFNSSTNVVVLASTNRADILDPALMRPGRFDRHIYLGPPDLKGRASIFKVHLRPLKLCTGIDVETLCRHLAALTPSFTGAEIAGVCNEAALIAARHLNQCINTEHFELAVERIIGGVEKKMQILQLEEKTTVAYHQAGHAVTGWFLKHADPIFKLSIVPRGRSLSS-SQYLCKEQHLFSQDQLFDRMCMMLGGRVSEHIFFHRITSGAHDDLRRATELAYAQIVQFGMNKAVGPVSFDRPQQGNTLCERPFGESTAQLIDLEVRSLIDAAFHRTHQLLVDKKEMVEKVAKCLLEKEILDRTDLVKLLGPRPF 723
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Medaka
Match: ENSORLT00000038203.1 (AFG3-like protein 1 [Source:NCBI gene;Acc:101159734])

HSP 1 Score: 389.423 bits (999), Expect = 1.036e-120
Identity = 195/445 (43.82%), Postives = 289/445 (64.94%), Query Frame = 1 
Query: 1807 FKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGF--HSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPF 3135
            F+D+AG  +AK+EI E + +L +P ++  LGA+ PKGA+L GPPG GKTLL KA A E +VPF   +G +F ++  G   A++R++F KA S AP I+FIDEIDA+G+ RG   +  +S+++ TLNQLLVEMDG  S   V+V A+TNR DILD AL+RPGRFDRHI +  P L+ R  +F ++L   +      ++ L   L+  TP  TGA+I+ +CNEAA+IA+R   + +  E F++A+ER+I G E K + L   E+   AYH+AGH + GW LK+ADPI K+SI+PR   L   +Q   + ++L + D L D + ++LGGR +E I F  ITSGA +DL++ ++LA+  + ++GM++ VG  SF   +Q       PF + T  LI++E   +I +A+ +   ++   +E +EK+A  LL+KE L   D+  L+GPRPF
Sbjct:  305 FEDVAGCEDAKLEIMELVNFLKHPHQYRDLGAKTPKGALLTGPPGTGKTLLAKATAGEVDVPFISVNGSEFQEVFVGVGPARIRDLFVKAHSMAPCILFIDEIDAVGRKRGSGNYMNQSEQENTLNQLLVEMDGFNSSTNVVVLASTNRADILDPALMRPGRFDRHIYLGPPDLKGRASIFKVHLRPLKLCTGIDVETLCRHLAALTPSFTGAEIAGVCNEAALIAARHLNQCINTEHFELAVERIIGGVEKKMQILQLEEKTTVAYHQAGHAVTGWFLKHADPIFKLSIVPRGRSLSS-SQYLCKEQHLFSQDQLFDRMCMMLGGRVSEHIFFHRITSGAHDDLRRATELAYAQIVQFGMNKAVGPVSFDRPQQGNTLCERPFGESTAQLIDLEVRSLIDAAFHRTHQLLVDKKEMVEKVAKCLLEKEILDRTDLVKLLGPRPF 748
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Planmine SMEST
Match: SMESG000077944.1 (SMESG000077944.1)

HSP 1 Score: 841.647 bits (2173), Expect = 0.000e+0
Identity = 407/407 (100.00%), Postives = 407/407 (100.00%), Query Frame = 1 
Query: 1921 MLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR 3141
            MLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR
Sbjct:    1 MLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFGR 407
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Planmine SMEST
Match: SMESG000006323.1 (SMESG000006323.1)

HSP 1 Score: 426.017 bits (1094), Expect = 1.795e-136
Identity = 212/450 (47.11%), Postives = 311/450 (69.11%), Query Frame = 1 
Query: 1798 ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHS--GESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSDR-LSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESITFDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLIGPRPFG 3138
            +T F D+AG   AKIEI EF+ +L NP K+  LGA++P+GA+L GPPG GKTLL KA A EANVPF   SG +F+++  G   +++R++F +A + AP I+F+DEIDAIG+ R   S  G S+++ TLNQLLVEMDG ++   V+V AATNR+DILD AL+RPGRFDR + V  P ++ R  LF ++L+  + ++    KN + R L+ +TPG +GAD++N+CNEAA+IA+R + + VT + FD A+ERVIAG E KT+ L   E+KI AYHEAGH + GW L++ DP+LKVSIIPR    LG+ Q   ++ YL   D ++D + + L GRA+E I F+   SGA++DL+KV+K A++ + + G SEKVGH SF + +  ++  + P+S+ T  LI+ EA  ++  +Y++   ++K  ++ +EK+A+ LL KE +   D+  L+GPRPF 
Sbjct:  155 KTKFSDVAGCEEAKIEIIEFVNFLKNPDKYAALGAKIPRGAILKGPPGTGKTLLAKATAGEANVPFLSISGSEFLELFVGVGPSRVRDMFSQARAHAPCILFVDEIDAIGRKRSGKSFGGHSEQESTLNQLLVEMDGFKTCENVVVLAATNRIDILDPALLRPGRFDRQVYVSLPNIKGRASLFKVHLAPIKTNVD---KNETSRKLAARTPGFSGADVANVCNEAALIAARENAEGVTFKHFDAAIERVIAGLEQKTQVLQPDEKKIVAYHEAGHAVAGWFLRHCDPLLKVSIIPRGKS-LGYAQYMPRDVYLMTQDQMLDSMGMTLAGRASEQIFFEKFGSGAQDDLQKVTKNAYSQIVQLGFSEKVGHLSFDLPQSRDYPMSKPYSEQTAQLIDEEARLMVKQSYERILELLKSKKDLVEKVALRLLDKEQIEKSDLLELLGPRPFA 600
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Planmine SMEST
Match: SMESG000026563.1 (SMESG000026563.1)

HSP 1 Score: 291.967 bits (746), Expect = 1.191e-86
Identity = 174/458 (37.99%), Postives = 266/458 (58.08%), Query Frame = 1 
Query: 1777 NNFRPKH--ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSD----RLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQ--KDFQNKYLKNYDMLVDEISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLI 3120
            N F+P     TTF DI G   AK +++  + +L NP KF +LGA LP+G +L+GPPG GKT L +A+A EA VPF Y S  +F +M  G  A+++RE+F  A + +P +IFIDE+DAI   +   S    + QTL+QLL+E+DG +S  G+IV +ATN  + LDKALIRPGRFD  + +  P  E RK LF LY+        G +K++ D    +L+  + G TGA+I N+ N+AA+IA   + K V +E    A +R++ G   K     E+ R I A+HEAGH L  ++   ++ I KV+IIPR    LGFT    D +  ++     L   I  LL G+ AE + +  D +T+G  +DLK+ + +A NMV   GMS+ +   ++  +       N   S   +++I+ E ++I+  ++++   ++  N EKL+ +A  LLK E+L   ++  +I
Sbjct:  117 NRFKPVKNISTTFCDIQGCDEAKQDLENLIHFLRNPEKFNELGATLPRGVILVGPPGVGKTSLARAVAGEAKVPFIYASASEFDEMYVGVGASRVRELFESAKAHSPCVIFIDELDAISNKKVDASLRQSQSQTLSQLLIELDGFQSTQGIIVLSATNNKEALDKALIRPGRFDLEVELVPPDFEGRKALFKLYV--------GKVKSIGDIDYEKLAKGSVGFTGAEIKNMVNQAALIAGMNNEKHVQSEDLWKARDRILMGVARKKVPDDETNR-ITAFHEAGHALTAFLTPDSEKIHKVTIIPRNHS-LGFTSFLGDKERHHM-TRSQLQARIDSLLAGKIAEELIYGPDKVTTGGSDDLKRATAIAQNMVMNLGMSQNMKFRTYSSSISGFQDSN--LSSQARSMIDEEVDRILHESHERVRKLLVENTEKLKTLAENLLKHETLDNSEVSEII 561
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Planmine SMEST
Match: SMESG000026563.1 (SMESG000026563.1)

HSP 1 Score: 291.967 bits (746), Expect = 1.939e-86
Identity = 174/458 (37.99%), Postives = 266/458 (58.08%), Query Frame = 1 
Query: 1777 NNFRPKH--ETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLGARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAAKLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMDGMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTLYLSKNQQHIQGSIKNLSD----RLSLQTPGMTGADISNICNEAAVIASRMDYKTVTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYADPILKVSIIPRTMGLLGFTQ--KDFQNKYLKNYDMLVDEISVLLGGRAAESITF--DYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFPFSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTFEDIETLI 3120
            N F+P     TTF DI G   AK +++  + +L NP KF +LGA LP+G +L+GPPG GKT L +A+A EA VPF Y S  +F +M  G  A+++RE+F  A + +P +IFIDE+DAI   +   S    + QTL+QLL+E+DG +S  G+IV +ATN  + LDKALIRPGRFD  + +  P  E RK LF LY+        G +K++ D    +L+  + G TGA+I N+ N+AA+IA   + K V +E    A +R++ G   K     E+ R I A+HEAGH L  ++   ++ I KV+IIPR    LGFT    D +  ++     L   I  LL G+ AE + +  D +T+G  +DLK+ + +A NMV   GMS+ +   ++  +       N   S   +++I+ E ++I+  ++++   ++  N EKL+ +A  LLK E+L   ++  +I
Sbjct:  148 NRFKPVKNISTTFCDIQGCDEAKQDLENLIHFLRNPEKFNELGATLPRGVILVGPPGVGKTSLARAVAGEAKVPFIYASASEFDEMYVGVGASRVRELFESAKAHSPCVIFIDELDAISNKKVDASLRQSQSQTLSQLLIELDGFQSTQGIIVLSATNNKEALDKALIRPGRFDLEVELVPPDFEGRKALFKLYV--------GKVKSIGDIDYEKLAKGSVGFTGAEIKNMVNQAALIAGMNNEKHVQSEDLWKARDRILMGVARKKVPDDETNR-ITAFHEAGHALTAFLTPDSEKIHKVTIIPRNHS-LGFTSFLGDKERHHM-TRSQLQARIDSLLAGKIAEELIYGPDKVTTGGSDDLKRATAIAQNMVMNLGMSQNMKFRTYSSSISGFQDSN--LSSQARSMIDEEVDRILHESHERVRKLLVENTEKLKTLAENLLKHETLDNSEVSEII 592
[Close]
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Planmine SMEST
Match: SMESG000077945.1 (SMESG000077945.1)

HSP 1 Score: 278.1 bits (710), Expect = 1.699e-85
Identity = 147/148 (99.32%), Postives = 147/148 (99.32%), Query Frame = 1 
Query: 1375 VHKVQLLSYFGRTFSKCSAVVYLQNDANRSYQEICIINEHPSVIRSKIDRIERDLKVNRKEAIPIQYSITNXXXXXXXXXXXXXRFRSRGLNALRSATKYHDLPQTKKLEKPSQNDLYYPTILKEMKERMDGEYNNFRPKHETTFKDI 1818
            VHKVQLLSYFGRTFSKCSAVVYLQNDANRSYQEICIINEHPSVIRSKIDRIERDLKVNRKEAIPIQYSITNLVLFVAVVLTAFTRFRSRGLNALRSATKYHDLPQTKKLEKPSQNDLYYPTILKEMKERMDGEYNNFRPKHETTFK I
Sbjct:  116 VHKVQLLSYFGRTFSKCSAVVYLQNDANRSYQEICIINEHPSVIRSKIDRIERDLKVNRKEAIPIQYSITNLVLFVAVVLTAFTRFRSRGLNALRSATKYHDLPQTKKLEKPSQNDLYYPTILKEMKERMDGEYNNFRPKHETTFKVI 263
The following BLAST results are available for this feature:
BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SPG72.050e-14848.67SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
SPG72.097e-14848.67SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
SPG71.191e-14748.67SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
SPG77.669e-14748.45SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
SPG76.556e-14248.45SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ppgn-11.000e-14250.44ParaPleGiN AAA protease family; Paraplegin [Sourc... [more]
ppgn-11.000e-14250.44ParaPleGiN AAA protease family; Paraplegin [Sourc... [more]
spg-74.570e-13147.87AFG3-like protein spg-7 [Source:UniProtKB/Swiss-P... [more]
ymel-11.700e-9841.61ATP-dependent zinc metalloprotease YME1 homolog [... [more]
ymel-11.700e-9841.61ATP-dependent zinc metalloprotease YME1 homolog [... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Spg73.442e-14348.02gene:FBgn0024992 transcript:FBtr0070502[more]
Spg73.442e-14348.02gene:FBgn0024992 transcript:FBtr0345716[more]
CG65121.173e-13548.43gene:FBgn0036702 transcript:FBtr0075252[more]
CG65122.270e-13448.43gene:FBgn0036702 transcript:FBtr0075251[more]
YME1L4.851e-9840.36gene:FBgn0034792 transcript:FBtr0071906[more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AL954648.32.121e-14748.34SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
AL954648.22.121e-14748.34SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
spg75.223e-14648.34SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
afg3l25.071e-13045.92AFG3-like AAA ATPase 2 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
si:ch1073-174d20.21.291e-12946.43si:ch1073-174d20.2 [Source:ZFIN;Acc:ZDB-GENE-12121... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan319.685e-14947.77tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512][more]
tspan314.070e-14847.77tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512][more]
tspan314.148e-14847.77tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512][more]
tspan311.271e-14747.77tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512][more]
tspan311.383e-14747.77tetraspanin 31 [Source:Xenbase;Acc:XB-GENE-942512][more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Spg72.466e-14847.92SPG7, paraplegin matrix AAA peptidase subunit [Sou... [more]
Spg78.885e-14747.70SPG7, paraplegin matrix AAA peptidase subunit [Sou... [more]
Afg3l13.783e-13148.31AFG3-like AAA ATPase 1 [Source:MGI Symbol;Acc:MGI:... [more]
Afg3l22.044e-12745.76AFG3-like AAA ATPase 2 [Source:MGI Symbol;Acc:MGI:... [more]
Spg75.954e-12543.11SPG7, paraplegin matrix AAA peptidase subunit [Sou... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9UQ90|SPG7_HUMAN3.683e-14648.45Paraplegin OS=Homo sapiens OX=9606 GN=SPG7 PE=1 SV... [more]
sp|Q3ULF4|SPG7_MOUSE6.215e-14647.70Paraplegin OS=Mus musculus OX=10090 GN=Spg7 PE=1 S... [more]
sp|Q7TT47|SPG7_RAT7.679e-14647.92Paraplegin OS=Rattus norvegicus OX=10116 GN=Spg7 P... [more]
sp|D0MGU8|FTSH_RHOM44.296e-14249.01ATP-dependent zinc metalloprotease FtsH OS=Rhodoth... [more]
sp|P40341|YTA12_YEAST2.706e-13750.67Mitochondrial respiratory chain complexes assembly... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1G2631.740e-15551.56AAA domain-containing protein OS=Helobdella robust... [more]
A0A0B7A7D24.038e-15351.79AAA domain-containing protein OS=Arion vulgaris OX... [more]
A0A0N4UJ611.034e-15253.10AAA domain-containing protein OS=Dracunculus medin... [more]
A0A443SN243.350e-15250.44Paraplegin-like protein OS=Leptotrombidium deliens... [more]
R7T3G82.044e-15151.56AAA domain-containing protein OS=Capitella teleta ... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
spg72.571e-14849.22SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
ENSAMXT00000029966.11.764e-13146.36pep primary_assembly:Astyanax_mexicanus-2.0:18:636... [more]
ENSAMXT00000003575.22.400e-13146.36pep primary_assembly:Astyanax_mexicanus-2.0:18:636... [more]
afg3l25.275e-13046.14AFG3-like AAA ATPase 2 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
afg3l21.503e-12946.14AFG3-like AAA ATPase 2 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
spg78.718e-13648.37SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
yme1l1b1.033e-9038.74YME1-like 1b [Source:ZFIN;Acc:ZDB-GENE-070410-25][more]
si:ch1073-174d20.23.231e-8347.20si:ch1073-174d20.2 [Source:ZFIN;Acc:ZDB-GENE-12121... [more]
vcp2.972e-4540.69valosin containing protein [Source:NCBI gene;Acc:3... [more]
psmc59.362e-4537.74proteasome 26S subunit, ATPase 5 [Source:ZFIN;Acc:... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
YTA123.897e-13950.67Mitochondrial inner membrane m-AAA protease compon... [more]
AFG31.688e-13849.34Mitochondrial inner membrane m-AAA protease compon... [more]
YME17.339e-7935.25Catalytic subunit of i-AAA protease complex; compl... [more]
RPT66.473e-4536.65ATPase of the 19S regulatory particle of the 26S p... [more]
AFG24.258e-4440.24ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO314221.274e-14548.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO405532.264e-13246.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494721.102e-9540.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO390061.006e-4836.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495248.065e-4637.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
spg73.087e-14748.78SPG7 matrix AAA peptidase subunit, paraplegin [Sou... [more]
si:ch1073-174d20.23.738e-13247.32AFG3-like protein 1 [Source:NCBI gene;Acc:10115769... [more]
afg3l25.801e-12745.54AFG3 like matrix AAA peptidase subunit 2 [Source:N... [more]
ENSORLT00000011850.27.851e-12143.82AFG3-like protein 1 [Source:NCBI gene;Acc:10115973... [more]
ENSORLT00000038203.11.036e-12043.82AFG3-like protein 1 [Source:NCBI gene;Acc:10115973... [more]
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BLAST of ATP-dependent zinc metalloprotease FtsH vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000077944.10.000e+0100.00SMESG000077944.1[more]
SMESG000006323.11.795e-13647.11SMESG000006323.1[more]
SMESG000026563.11.191e-8637.99SMESG000026563.1[more]
SMESG000026563.11.939e-8637.99SMESG000026563.1[more]
SMESG000077945.11.699e-8599.32SMESG000077945.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030149 ID=SMED30030149|Name=ATP-dependent zinc metalloprotease FtsH|organism=Schmidtea mediterranea sexual|type=transcript|length=3141bp
GTATTATTATTAATAATTCTATGAAGAAAAGATGAGACAAGAAGAACAAT
GCATTTATTTATTACCATACATAATGAGCGGTGAACAGAGCTCGCGTCTA
TAAGTAAGATATAACGACCGTGCTACCCTCAAAGTGAGGTCAAAGTGTCT
GGTATAATCATAGTTTTCATTTTAACATCACAATAGCTAAATCATCGAAG
AATGGTGTCATTTAAACTGTGATGTTACGTGAATAATTATGCAAATAATT
ATTATAACAAAAGTTAACGATGACGTTATTTGACATTGACGTCACGTAAC
ATATGACGAAACAACGTTGAACCATGTCGTAATAGGTAGTGTGGTTGCGT
AACCATATGTGCTACATAGAGTCCGGCGATTTCATAATCATCACATAACC
AAATATGCTATGTAAAACACGAGGGCTACGTATTAACGTGTGTAATTACA
TCACCATTTCCAGTCTGAGCGTTATGTAATACATAACCCTCACCTTATAG
GGCTACACTCCTTATAGTGTAGTACTGATGAAACAGGTGAAGCTATGTTA
AAGGTATGTTAGACTATTTGGAAGATTGGAATATCAAACACCGGATTCAG
GCAATGGCAGTCGATACAACTAGTAACATCACTGGTAGGAATCTTGTTGA
TTGTATCCTCATCGAGTCAATGATCGGAAGAAACCTGCTGCATCTTGCAT
GCCACCATCACATCATGGCTATAATTTCTGAAAAGCCTTTTGCTGTATGT
GATATGCGGTATACTGGACCTGACATTCTCTTGTTCAAGCGTTTCCAGCA
AAAATGGAAATTTGTAGACAAGGAAGCTATTGGTGACTACATTATAGACA
AGGAAGATATAATTATGTTCTGCAAATTGCAACTGGCAATTACTCAAGCA
CACAGCGACTACCGTGTGTTTCTAAAATTGATCATTGTCTCTCTTGGTGG
CATTCCTCCAATAGAAATCCGATTCCTGCATCCTGTGGTATTCCATTGAG
CTAGATGGATGTCTAGCGTAATCTATTCGATCAAAATAATTCTCTTCCTT
GTTCAGCTAATCGAACTCTGAGATTTGACATTTGTATAGTTTTGCAGCTT
ACTGAATATTACTAACATTATTTATAATTCTGTGGCTTCAATACATAATT
TTATACGAGTTTTCTTTCTACGAAACGAGGAACATTAACACAGTTATTTT
TATTCATTCTCACTTGAACATATCCTAAACTTTCGATCTCAGAAAGGAAA
TTTGATTTGTAAATAGTTTCATGAGATGCCGTGTTCCTACAATAACAAAA
CTAAAAAATTATTTTAATTAAATATCGATCATATCTGTCATTTATCTTTG
AAGTTGTATTATTATATTTTATAGGTTCATAAAGTTCAATTACTCAGTTA
TTTTGGACGTACTTTTTCTAAATGTAGTGCAGTAGTGTATTTGCAAAATG
ACGCCAATCGAAGCTATCAGGAAATCTGTATTATTAACGAACACCCATCA
GTAATAAGATCTAAAATCGACAGAATAGAGCGTGATTTAAAAGTAAACCG
AAAAGAAGCTATTCCAATTCAATATAGTATAACAAACTTGGTTTTGTTTG
TGGCAGTCGTTCTAACAGCATTTACACGCTTTCGTTCTCGTGGACTTAAT
GCACTCAGATCTGCCACAAAGTATCATGATTTGCCTCAAACGAAGAAATT
AGAGAAACCATCACAAAATGATTTATATTACCCAACAATTTTGAAGGAAA
TGAAGGAACGCATGGATGGTGAATATAATAACTTTCGACCGAAACATGAA
ACTACATTTAAGGATATAGCCGGACTTCATAATGCCAAAATAGAAATTCA
AGAATTTCTCCAATATTTGAATAATCCAAGTAAATTTATTAAATTGGGTG
CTCGCCTTCCAAAAGGAGCTATGCTTCTCGGACCTCCTGGTTGTGGAAAA
ACACTATTGGTCAAAGCATTGGCAAGTGAGGCAAATGTTCCATTTTTTTA
TAAATCTGGCCCCGATTTTATTGATATGAGAGGTGGACAAGCTGCTGCTA
AATTAAGAGAAGTGTTTAGGAAAGCTAGTTCTAGTGCTCCGTCAATTATT
TTCATCGATGAAATTGATGCCATTGGTAAAACGCGCGGATTTCATTCGGG
TGAAAGTGATGAGGATCAAACTTTAAATCAGTTATTGGTTGAAATGGATG
GAATGGAATCTGTTGCTGGAGTAATTGTATTCGCTGCTACCAACAGAGTT
GATATACTTGATAAAGCTTTAATAAGGCCTGGGAGATTTGACCGTCATAT
TCTCGTAGACTATCCCGTTCTAGAAGAAAGGAAGGAATTGTTCACTTTAT
ATCTATCAAAAAATCAACAACATATTCAAGGGTCTATTAAAAATCTGAGC
GACAGATTAAGTCTTCAAACACCTGGCATGACAGGTGCTGATATTTCTAA
TATTTGCAATGAAGCTGCTGTCATAGCATCTAGAATGGATTACAAAACTG
TTACAAATGAATGTTTTGACATTGCTTTAGAACGTGTTATTGCGGGATCT
GAATCTAAAACAAGATTTTTATCAGAATCCGAAAGGAAAATAAATGCATA
CCACGAAGCTGGACATGTTCTAGTTGGTTGGATGTTAAAATATGCTGACC
CTATTTTAAAAGTATCCATCATCCCAAGAACTATGGGATTGTTGGGGTTC
ACACAAAAAGATTTTCAAAATAAATATTTGAAAAATTATGATATGTTGGT
AGATGAAATTTCAGTACTTCTTGGAGGCAGAGCTGCCGAGTCAATTACTT
TTGATTATATTACATCCGGAGCAGAAAATGATCTTAAAAAAGTCTCCAAA
TTGGCATTTAATATGGTTCGAGAATGGGGTATGAGTGAAAAAGTTGGACA
TTTTAGTTTTCAGGTAACGGAGCAAGATGAGCATTCAGGTAATTTTCCGT
TTAGTAAATATACCCAAGCGCTAATAGAAATGGAAGCTAATCAAATTATA
GTATCTGCTTACAAGAAAGCTGAAAATGTAATCAAAGGAAACCGTGAAAA
ATTAGAGAAAATCGCAGTGGAACTGTTGAAGAAAGAATCGCTTACATTTG
AAGATATTGAAACCCTCATAGGTCCTAGACCGTTTGGTAGA
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protein sequence of SMED30030149-orf-1

>SMED30030149-orf-1 ID=SMED30030149-orf-1|Name=SMED30030149-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=464bp
MKERMDGEYNNFRPKHETTFKDIAGLHNAKIEIQEFLQYLNNPSKFIKLG
ARLPKGAMLLGPPGCGKTLLVKALASEANVPFFYKSGPDFIDMRGGQAAA
KLREVFRKASSSAPSIIFIDEIDAIGKTRGFHSGESDEDQTLNQLLVEMD
GMESVAGVIVFAATNRVDILDKALIRPGRFDRHILVDYPVLEERKELFTL
YLSKNQQHIQGSIKNLSDRLSLQTPGMTGADISNICNEAAVIASRMDYKT
VTNECFDIALERVIAGSESKTRFLSESERKINAYHEAGHVLVGWMLKYAD
PILKVSIIPRTMGLLGFTQKDFQNKYLKNYDMLVDEISVLLGGRAAESIT
FDYITSGAENDLKKVSKLAFNMVREWGMSEKVGHFSFQVTEQDEHSGNFP
FSKYTQALIEMEANQIIVSAYKKAENVIKGNREKLEKIAVELLKKESLTF
EDIETLIGPRPFGR
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protein sequence of SMED30030149-orf-2

>SMED30030149-orf-2 ID=SMED30030149-orf-2|Name=SMED30030149-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=148bp
MLDYLEDWNIKHRIQAMAVDTTSNITGRNLVDCILIESMIGRNLLHLACH
HHIMAIISEKPFAVCDMRYTGPDILLFKRFQQKWKFVDKEAIGDYIIDKE
DIIMFCKLQLAITQAHSDYRVFLKLIIVSLGGIPPIEIRFLHPVVFH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0016887ATPase activity
GO:0005524ATP binding
GO:0004222metalloendopeptidase activity
GO:0016714oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0000166nucleotide binding
GO:0008233peptidase activity
GO:0008237metallopeptidase activity
GO:0008270zinc ion binding
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0030163protein catabolic process
GO:0006508proteolysis
GO:0055114oxidation-reduction process
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
Vocabulary: INTERPRO
TermDefinition
IPR037219Peptidase_M41-like
IPR005936FtsH
IPR041569AAA_lid_3
IPR003593AAA+_ATPase
IPR003959ATPase_AAA_core
IPR000642Peptidase_M41
IPR027417P-loop_NTPase
IPR003960ATPase_AAA_CS
IPR019774Aromatic-AA_hydroxylase_C
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003593AAA+ ATPase domainSMARTSM00382AAA_5coord: 53..190
e-value: 8.2E-20
score: 81.8
IPR037219Peptidase M41-likeGENE3DG3DSA:1.20.58.760coord: 273..461
e-value: 6.3E-61
score: 207.5
IPR037219Peptidase M41-likeSUPERFAMILYSSF140990FtsH protease domain-likecoord: 274..458
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 9..188
e-value: 1.9E-60
score: 205.6
NoneNo IPR availableGENE3DG3DSA:1.10.8.60coord: 189..270
e-value: 4.2E-15
score: 57.3
NoneNo IPR availablePANTHERPTHR43655FAMILY NOT NAMEDcoord: 16..463
NoneNo IPR availablePANTHERPTHR43655:SF8PARAPLEGINcoord: 16..463
NoneNo IPR availableCDDcd00009AAAcoord: 32..188
e-value: 1.21661E-23
score: 94.5203
IPR005936Peptidase, FtsHTIGRFAMTIGR01241TIGR01241coord: 15..457
e-value: 2.7E-156
score: 519.1
IPR041569AAA ATPase, AAA+ lid domainPFAMPF17862AAA_lid_3coord: 218..256
e-value: 7.8E-9
score: 35.2
IPR003959ATPase, AAA-type, corePFAMPF00004AAAcoord: 58..187
e-value: 6.3E-40
score: 136.7
IPR000642Peptidase M41PFAMPF01434Peptidase_M41coord: 273..455
e-value: 3.8E-54
score: 183.4
IPR003960ATPase, AAA-type, conserved sitePROSITEPS00674AAAcoord: 158..176
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 16..263