Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030132 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: SCYL2 (SCY1 like pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:19286]) HSP 1 Score: 208.379 bits (529), Expect = 1.432e-61 Identity = 119/455 (26.15%), Postives = 248/455 (54.51%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LGN L + IK +KL D+E K+G+ Q+++ L +LH+S +++H N+ P +++ +SG WK+ G F S+TN +E++ +W P + P+ +Y+APE L + DM+SLG ++ + GK + NK ++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + + D+ ++ + T ++++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTNIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFV-NPDMVPFVLPNVLLIAEECTKEEYVKLILPELGPVFKQQE--PIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYK 551 HSP 2 Score: 50.0618 bits (118), Expect = 1.432e-61 Identity = 26/88 (29.55%), Postives = 47/88 (53.41%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G + WKI++ + + ++F+F+K++ +K K + ++I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQII-DSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: SCYL2 (SCY1 like pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:19286]) HSP 1 Score: 207.994 bits (528), Expect = 2.040e-61 Identity = 119/455 (26.15%), Postives = 248/455 (54.51%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LGN L + IK +KL D+E K+G+ Q+++ L +LH+S +++H N+ P +++ +SG WK+ G F S+TN +E++ +W P + P+ +Y+APE L + DM+SLG ++ + GK + NK ++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + + D+ ++ + T ++++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTNIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFV-NPDMVPFVLPNVLLIAEECTKEEYVKLILPELGPVFKQQE--PIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYK 551 HSP 2 Score: 50.0618 bits (118), Expect = 2.040e-61 Identity = 27/88 (30.68%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G + WKI++ + + ++F+F+K++ +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQK-FEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: SCYL2 (SCY1 like pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:19286]) HSP 1 Score: 206.838 bits (525), Expect = 4.027e-61 Identity = 120/459 (26.14%), Postives = 250/459 (54.47%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTII----LQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LGN L + IK +KL D+E K+G+ Q+++ L +LH+S +++H N+ P +++ +SG WK+ G F S+TN +E++ +W P + P+ +Y+APE L + DM+SLG ++ + GK + NK ++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + + D+ ++ + T ++++ + P + + + + I S +I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTNIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFV-NPDMVPFVLPNVLLIAEECTKEEYVKLILPELGPVFKQQE--PIQASNMILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYK 555 HSP 2 Score: 50.0618 bits (118), Expect = 4.027e-61 Identity = 27/88 (30.68%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G + WKI++ + + ++F+F+K++ +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQK-FEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: SCYL2 (SCY1 like pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:19286]) HSP 1 Score: 50.8322 bits (120), Expect = 1.685e-7 Identity = 23/76 (30.26%), Postives = 41/76 (53.95%), Query Frame = 3
Query: 690 VIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDM 911
++H N+ P +++ +SG WK+ G F S+TN +E++ +W P + P+ +Y+APE L + DM
Sbjct: 1 MVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDM 76
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: AURKA (aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393]) HSP 1 Score: 51.6026 bits (122), Expect = 4.584e-6 Identity = 40/162 (24.69%), Postives = 70/162 (43.21%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQ----PDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQ 1115
I +L + L Y H S++VIH ++ P +L+ +G K I D WS P + LDY+ PE+ G +D++SLG+L C + GK AN +E +K S + P + E ++++ +++ P+ +
Sbjct: 237 ITELANALSYCH-SKRVIHRDIKPENLLLGSAGELK-----------------IADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVL-CYEFLVGKPPFEAN--------TYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: ZC581.9 (pep chromosome:WBcel235:I:6665077:6673840:-1 gene:WBGene00022635.1 transcript:ZC581.9b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC581.9) HSP 1 Score: 162.54 bits (410), Expect = 3.917e-41 Identity = 110/378 (29.10%), Postives = 193/378 (51.06%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS--NTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGG--PITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFL--QSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSL 1583
+IL + H +EE + ++FATE+I G+L N++ ++ L LEIK G+ Q+ D + YLH S +++H N+ P + +T + WK+ G F + NC W+ K P QPDLD++APE G +T++ D+FSLG+LIC Y GGK LI+A L Y + +L I++ L L + + K+L+ ++ RP QL SL+K+FDD L ++ + + + + S Q+L IP + + +R+ P F ++E ++Y + L ++ + MKP I ++ A N + + IL+ + LF ++++E ++ K + +++ + SE Q +A+ L
Sbjct: 97 RILHMEHSLEETKDYISFATEQIFGNLENVVTDE--------------SLDRLEIKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEPNC----YPCYPWTKKLPPCLQPDLDFLAPENLAPGQTTVTSAADVFSLGVLICWIYAGGKRLIDAKSNLETYHIVVGQLDAALQCISNELGPNLKDSMAKVLSLDVEVRPTVQLLSLIKHFDDPCLSALRQLDDIAQVFDPSQKSHFLSQTLNVAIPHISESVWFNRVLPRFNEQLLELPEMYYPITKPLFHILEHCE-SHNIHKMKPWIRKLMEAAPHNKLLRA-FILENMSALFRRLSDEFVEDKCLDVIILSLKSEDTSLQSSAVRGL 454
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: ZC581.9 (pep chromosome:WBcel235:I:6665077:6673602:-1 gene:WBGene00022635.1 transcript:ZC581.9d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC581.9) HSP 1 Score: 162.54 bits (410), Expect = 4.385e-41 Identity = 110/378 (29.10%), Postives = 193/378 (51.06%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS--NTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGG--PITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFL--QSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSL 1583
+IL + H +EE + ++FATE+I G+L N++ ++ L LEIK G+ Q+ D + YLH S +++H N+ P + +T + WK+ G F + NC W+ K P QPDLD++APE G +T++ D+FSLG+LIC Y GGK LI+A L Y + +L I++ L L + + K+L+ ++ RP QL SL+K+FDD L ++ + + + + S Q+L IP + + +R+ P F ++E ++Y + L ++ + MKP I ++ A N + + IL+ + LF ++++E ++ K + +++ + SE Q +A+ L
Sbjct: 110 RILHMEHSLEETKDYISFATEQIFGNLENVVTDE--------------SLDRLEIKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEPNC----YPCYPWTKKLPPCLQPDLDFLAPENLAPGQTTVTSAADVFSLGVLICWIYAGGKRLIDAKSNLETYHIVVGQLDAALQCISNELGPNLKDSMAKVLSLDVEVRPTVQLLSLIKHFDDPCLSALRQLDDIAQVFDPSQKSHFLSQTLNVAIPHISESVWFNRVLPRFNEQLLELPEMYYPITKPLFHILEHCE-SHNIHKMKPWIRKLMEAAPHNKLLRA-FILENMSALFRRLSDEFVEDKCLDVIILSLKSEDTSLQSSAVRGL 467
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: ZC581.9 (pep chromosome:WBcel235:I:6665077:6673807:-1 gene:WBGene00022635.1 transcript:ZC581.9c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC581.9) HSP 1 Score: 162.54 bits (410), Expect = 5.271e-41 Identity = 113/404 (27.97%), Postives = 207/404 (51.24%), Query Frame = 3
Query: 399 LDEKRSFVIFFEKKFFSYKVLII---QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS--NTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGG--PITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFL--QSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSL 1583
L + +++ +F K+ + +++ + +IL + H +EE + ++FATE+I G+L N++ ++ L LEIK G+ Q+ D + YLH S +++H N+ P + +T + WK+ G F + NC W+ K P QPDLD++APE G +T++ D+FSLG+LIC Y GGK LI+A L Y + +L I++ L L + + K+L+ ++ RP QL SL+K+FDD L ++ + + + + S Q+L IP + + +R+ P F ++E ++Y + L ++ + MKP I ++ A N + + IL+ + LF ++++E ++ K + +++ + SE Q +A+ L
Sbjct: 116 LGKSKTYSMFDLIKYETQQLMGLIHPRILHMEHSLEETKDYISFATEQIFGNLENVVTDE--------------SLDRLEIKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEPNC----YPCYPWTKKLPPCLQPDLDFLAPENLAPGQTTVTSAADVFSLGVLICWIYAGGKRLIDAKSNLETYHIVVGQLDAALQCISNELGPNLKDSMAKVLSLDVEVRPTVQLLSLIKHFDDPCLSALRQLDDIAQVFDPSQKSHFLSQTLNVAIPHISESVWFNRVLPRFNEQLLELPEMYYPITKPLFHILEHCE-SHNIHKMKPWIRKLMEAAPHNKLLRA-FILENMSALFRRLSDEFVEDKCLDVIILSLKSEDTSLQSSAVRGL 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: ZC581.9 (pep chromosome:WBcel235:I:6665077:6670409:-1 gene:WBGene00022635.1 transcript:ZC581.9a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC581.9) HSP 1 Score: 162.155 bits (409), Expect = 5.745e-41 Identity = 113/404 (27.97%), Postives = 207/404 (51.24%), Query Frame = 3
Query: 399 LDEKRSFVIFFEKKFFSYKVLII---QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS--NTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGG--PITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFL--QSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSL 1583
L + +++ +F K+ + +++ + +IL + H +EE + ++FATE+I G+L N++ ++ L LEIK G+ Q+ D + YLH S +++H N+ P + +T + WK+ G F + NC W+ K P QPDLD++APE G +T++ D+FSLG+LIC Y GGK LI+A L Y + +L I++ L L + + K+L+ ++ RP QL SL+K+FDD L ++ + + + + S Q+L IP + + +R+ P F ++E ++Y + L ++ + MKP I ++ A N + + IL+ + LF ++++E ++ K + +++ + SE Q +A+ L
Sbjct: 109 LGKSKTYSMFDLIKYETQQLMGLIHPRILHMEHSLEETKDYISFATEQIFGNLENVVTDE--------------SLDRLEIKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEPNC----YPCYPWTKKLPPCLQPDLDFLAPENLAPGQTTVTSAADVFSLGVLICWIYAGGKRLIDAKSNLETYHIVVGQLDAALQCISNELGPNLKDSMAKVLSLDVEVRPTVQLLSLIKHFDDPCLSALRQLDDIAQVFDPSQKSHFLSQTLNVAIPHISESVWFNRVLPRFNEQLLELPEMYYPITKPLFHILEHCE-SHNIHKMKPWIRKLMEAAPHNKLLRA-FILENMSALFRRLSDEFVEDKCLDVIILSLKSEDTSLQSSAVRGL 492
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: bma (gene:FBgn0085385 transcript:FBtr0331579) HSP 1 Score: 213.386 bits (542), Expect = 4.884e-74 Identity = 157/541 (29.02%), Postives = 267/541 (49.35%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLG--------------------------NDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS-NTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVL--LSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRR-KLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEM--XXXXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFE 1994
+IL++ H +EE+ +TLAFA+E I SL+N+L L Q A A K++ D+E+K+G QLT+ L YLH S VIH NV PS++LIT+ G WK+ G +V N N I WS + KM QP+LD++APE Q + DMFSLG++IC + G+ LI A + SNY K++E L + LP AL E +M +++ RP +QL L+KYF D + L +VN ++ + + + +L E +P P++L I+P I + ++ + +M +Q +TL ++ M + I K SI S IL+ + + K ED+ +MP+L + ++ Q AA+ ++ ID+ ++ ++LPK+K + + K+ + L + ++ +E + ++DEV+P L I+ D +I+M ++ Y ++ + ++ L+ H NP L +++L +LE +D +Q + +
Sbjct: 103 RILQIYHTVEESADTLAFASEPIFASLSNVLAFHESKTYEATNVAPAAGGAAASQAQAAANTLPQRPAHA-KEYNFLDMELKYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLAGMEYVERMNENDLNSSIPCPPWSNRVSKMAQPNLDFMAPETQSTSKCSLLSDMFSLGMVICAVFNNGRPLIQAGNSTSNYAKQMETLDDLVHKLMPRLPIALQEATSRMASRDATARPTAQLLQLIKYFIDTPINALKFLDVVNMKDTQQKSQF-YKTTLIEAMPMIPRKLWWQNIWPMLKSEI-NNNEVLAAVLQPVMLFVQEATLTEYDTLMSATMKVIYNTPK--SIQASVTILENLHLIIEKTKPEDVTTDIMPMLFYSFDGSTIQVQSAAVVAVANVFDSIDELSIRRMVLPKVKQVFEKNITDPKIVQNVLMCIERVMDRMERAQVMDEVLPLLANIRIPDPDIIMRTVRIYHKLFVDKTYGLTVETMATNVLPLLIPHTVNPSLNFEQYCYLLEVLQQMLEAIDRQQRNKLK 638 HSP 2 Score: 86.2705 bits (212), Expect = 4.884e-74 Identity = 41/89 (46.07%), Postives = 56/89 (62.92%), Query Frame = 2
Query: 206 TNVTSLNIGQSW--NNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
TNV + Q+ NP+++ F + K G E+ W+I+DA R D +CS+FIFEK+IAEKLHKPRRKE I + L+ V L+ F H
Sbjct: 13 TNVAASTATQAVADGNPITQYFEIGKPVACAGPELVWRIHDAYRKSDNKECSVFIFEKKIAEKLHKPRRKETITELLKSSVKTLERFRH 101
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: bma (gene:FBgn0085385 transcript:FBtr0331577) HSP 1 Score: 213.001 bits (541), Expect = 5.962e-74 Identity = 157/541 (29.02%), Postives = 267/541 (49.35%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLG--------------------------NDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS-NTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVL--LSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRR-KLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEM--XXXXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFE 1994
+IL++ H +EE+ +TLAFA+E I SL+N+L L Q A A K++ D+E+K+G QLT+ L YLH S VIH NV PS++LIT+ G WK+ G +V N N I WS + KM QP+LD++APE Q + DMFSLG++IC + G+ LI A + SNY K++E L + LP AL E +M +++ RP +QL L+KYF D + L +VN ++ + + + +L E +P P++L I+P I + ++ + +M +Q +TL ++ M + I K SI S IL+ + + K ED+ +MP+L + ++ Q AA+ ++ ID+ ++ ++LPK+K + + K+ + L + ++ +E + ++DEV+P L I+ D +I+M ++ Y ++ + ++ L+ H NP L +++L +LE +D +Q + +
Sbjct: 103 RILQIYHTVEESADTLAFASEPIFASLSNVLAFHESKTYEATNVAPAAGGAAASQAQAAANTLPQRPAHA-KEYNFLDMELKYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLAGMEYVERMNENDLNSSIPCPPWSNRVSKMAQPNLDFMAPETQSTSKCSLLSDMFSLGMVICAVFNNGRPLIQAGNSTSNYAKQMETLDDLVHKLMPRLPIALQEATSRMASRDATARPTAQLLQLIKYFIDTPINALKFLDVVNMKDTQQKSQF-YKTTLIEAMPMIPRKLWWQNIWPMLKSEI-NNNEVLAAVLQPVMLFVQEATLTEYDTLMSATMKVIYNTPK--SIQASVTILENLHLIIEKTKPEDVTTDIMPMLFYSFDGSTIQVQSAAVVAVANVFDSIDELSIRRMVLPKVKQVFEKNITDPKIVQNVLMCIERVMDRMERAQVMDEVLPLLANIRIPDPDIIMRTVRIYHKLFVDKTYGLTVETMATNVLPLLIPHTVNPSLNFEQYCYLLEVLQQMLEAIDRQQRNKLK 638 HSP 2 Score: 86.2705 bits (212), Expect = 5.962e-74 Identity = 41/89 (46.07%), Postives = 56/89 (62.92%), Query Frame = 2
Query: 206 TNVTSLNIGQSW--NNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
TNV + Q+ NP+++ F + K G E+ W+I+DA R D +CS+FIFEK+IAEKLHKPRRKE I + L+ V L+ F H
Sbjct: 13 TNVAASTATQAVADGNPITQYFEIGKPVACAGPELVWRIHDAYRKSDNKECSVFIFEKKIAEKLHKPRRKETITELLKSSVKTLERFRH 101
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: bma (gene:FBgn0085385 transcript:FBtr0331578) HSP 1 Score: 213.001 bits (541), Expect = 5.962e-74 Identity = 157/541 (29.02%), Postives = 267/541 (49.35%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLG--------------------------NDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS-NTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVL--LSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRR-KLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEM--XXXXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFE 1994
+IL++ H +EE+ +TLAFA+E I SL+N+L L Q A A K++ D+E+K+G QLT+ L YLH S VIH NV PS++LIT+ G WK+ G +V N N I WS + KM QP+LD++APE Q + DMFSLG++IC + G+ LI A + SNY K++E L + LP AL E +M +++ RP +QL L+KYF D + L +VN ++ + + + +L E +P P++L I+P I + ++ + +M +Q +TL ++ M + I K SI S IL+ + + K ED+ +MP+L + ++ Q AA+ ++ ID+ ++ ++LPK+K + + K+ + L + ++ +E + ++DEV+P L I+ D +I+M ++ Y ++ + ++ L+ H NP L +++L +LE +D +Q + +
Sbjct: 103 RILQIYHTVEESADTLAFASEPIFASLSNVLAFHESKTYEATNVAPAAGGAAASQAQAAANTLPQRPAHA-KEYNFLDMELKYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLAGMEYVERMNENDLNSSIPCPPWSNRVSKMAQPNLDFMAPETQSTSKCSLLSDMFSLGMVICAVFNNGRPLIQAGNSTSNYAKQMETLDDLVHKLMPRLPIALQEATSRMASRDATARPTAQLLQLIKYFIDTPINALKFLDVVNMKDTQQKSQF-YKTTLIEAMPMIPRKLWWQNIWPMLKSEI-NNNEVLAAVLQPVMLFVQEATLTEYDTLMSATMKVIYNTPK--SIQASVTILENLHLIIEKTKPEDVTTDIMPMLFYSFDGSTIQVQSAAVVAVANVFDSIDELSIRRMVLPKVKQVFEKNITDPKIVQNVLMCIERVMDRMERAQVMDEVLPLLANIRIPDPDIIMRTVRIYHKLFVDKTYGLTVETMATNVLPLLIPHTVNPSLNFEQYCYLLEVLQQMLEAIDRQQRNKLK 638 HSP 2 Score: 86.2705 bits (212), Expect = 5.962e-74 Identity = 41/89 (46.07%), Postives = 56/89 (62.92%), Query Frame = 2
Query: 206 TNVTSLNIGQSW--NNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
TNV + Q+ NP+++ F + K G E+ W+I+DA R D +CS+FIFEK+IAEKLHKPRRKE I + L+ V L+ F H
Sbjct: 13 TNVAASTATQAVADGNPITQYFEIGKPVACAGPELVWRIHDAYRKSDNKECSVFIFEKKIAEKLHKPRRKETITELLKSSVKTLERFRH 101
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: CG1951 (gene:FBgn0039623 transcript:FBtr0085342) HSP 1 Score: 197.208 bits (500), Expect = 7.902e-57 Identity = 126/453 (27.81%), Postives = 236/453 (52.10%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTE--EQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
+L V HP+EE+ ++LAFATE + SLAN++G+++R + KL D+EI+HG+ QL D L++LH +++H N++ T++I ++ WK+FG F +N T+ +++ + QP L+Y APEL L T D+FSLG+LI T Y G K L S++ + +L++ + +P L E ++ +L+ RP + YF D+ + ++ + + + + +K F + LP+IIP P + I P+ + S + + +L+ + S+ ++ DH+ P + I + I I +Q ++ L E+++ V+P+L + + ++ + Q L L F ID + N +LP+IK + + + V+ + L ++ L+ L+ +++DE++PFL +I++ + I+M +I YK
Sbjct: 99 HVLTVQHPLEESRDSLAFATEPVFASLANVVGDNVR---------SEKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGFDFCIANQPATDGTPHWPFREYTTSLHVLAQPSLEYTAPELALNSVNTPDSDLFSLGVLIFTIYAG-KPLKMFGSDYSSFRRYANDLNQRKYPPMNAVPSELTESLKALLHPSANLRPKLHELKQIAYFQDVGVKTLSYLDSLYQWDNLQKSKFYKGLPQIIPTLPHRVNLHSILPYLVKEFVNSPMIPFVLPNVLLIA-EMSSQREYCDHILPHLKPIFKL--TDPIQILLIFMQKMDLLLKLTPAEEVKQSVLPLLYRSLECDMPQIQDLCLAVLPTFSTLIDYNAMKNSVLPRIKKLCLQSSNVSVKVNCLISIGKLLENLDKWLVLDEILPFLQQIQSREPAIIMGIIGIYK 538 HSP 2 Score: 44.669 bits (104), Expect = 7.902e-57 Identity = 28/88 (31.82%), Postives = 48/88 (54.55%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
V V++L+ G N ++R + V +Q + GV + WK+Y+ + + S+F+FEK+ E+ K R E + + LR+ V QL H
Sbjct: 12 VQTVSTLS-GVLPGNNVTREYEVLEQVCTAGVGLMWKVYNGHKKSTKQEVSVFVFEKKSLERWSKDDR-ETMLETLRRGVQQLTKIRH 97
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: aurB (gene:FBgn0024227 transcript:FBtr0080180) HSP 1 Score: 49.6766 bits (117), Expect = 6.224e-6 Identity = 43/174 (24.71%), Postives = 71/174 (40.80%), Query Frame = 3
Query: 594 QAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQ----PDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYR 1103
+ H+ + YQ+ + L Y H + VIH ++ P +L+T + + ++ D WSA P + LDY+ PE+ G S+D + LG+L C + G +N T S Y K + + S S L + E + +L KE + R
Sbjct: 143 RGAPNHRFDEPRSAKYTYQVANALNYCHLNN-VIHRDLKPENILLTST-----------------DDLKLADFGWSAHTPNNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGIL-CYEFVVGCPPFESNSTESTYSK----IRRMEISYPSHLSKGCKELIGGLLRKESKGR 293
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: SCYL2 (si:ch211-244b2.1 [Source:ZFIN;Acc:ZDB-GENE-041210-205]) HSP 1 Score: 200.675 bits (509), Expect = 1.698e-60 Identity = 118/455 (25.93%), Postives = 243/455 (53.41%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCT--EEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG L IK +KL D+E K+G+ Q+++ L +LH+ +++H N+ +++ +SG WK+ G F S++N + E + +W P + P+ +Y+APE L ++ DM+SLG+LI + GK + NK ++ +++++L + S +P+ + + V+ +L+ RP++ + + +FDD+ +++ + ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P +T + + + I LQ ++ L K ED++ V+P++ + + + V+ Q L+ + F I+ ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGQWDNLPSPVPTDIKDYKLYDVETKYGLLQVSEGLSFLHSGVKMVHGNLCSENIILNKSGAWKIMGFDFSISSSNPSDAEPKYVCKEWDPNLPPLCLPNPEYVAPEYILSVSCDSASDMYSLGVLIHAVFNEGKPVFKVNKQDIFKSFSRQLDQLSHLSPGVLSQIPEEVRQHVKMLLSVTSNVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVVVYRILPALMSEFVNP-DMVPFILPNVLLIAEECTKEEYVRLVLPDLTPVFKMQE--PVQILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRAVEAPSVQIQELCLNIIPTFANLIEYPSMKNSLIPRIKSTCLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGILGIYK 551 HSP 2 Score: 53.9138 bits (128), Expect = 1.698e-60 Identity = 28/88 (31.82%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G M W+IY+ + + ++F+F+K++ ++ K K+ I D L+K + QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFEVGKHIASGGPGMSWRIYNGTKKSTKQEVAVFVFDKKVIDRYQK-FEKDQIIDSLKKGIQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: SCYL2 (si:ch211-244b2.1 [Source:ZFIN;Acc:ZDB-GENE-041210-205]) HSP 1 Score: 200.675 bits (509), Expect = 1.698e-60 Identity = 118/455 (25.93%), Postives = 243/455 (53.41%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCT--EEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG L IK +KL D+E K+G+ Q+++ L +LH+ +++H N+ +++ +SG WK+ G F S++N + E + +W P + P+ +Y+APE L ++ DM+SLG+LI + GK + NK ++ +++++L + S +P+ + + V+ +L+ RP++ + + +FDD+ +++ + ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P +T + + + I LQ ++ L K ED++ V+P++ + + + V+ Q L+ + F I+ ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGQWDNLPSPVPTDIKDYKLYDVETKYGLLQVSEGLSFLHSGVKMVHGNLCSENIILNKSGAWKIMGFDFSISSSNPSDAEPKYVCKEWDPNLPPLCLPNPEYVAPEYILSVSCDSASDMYSLGVLIHAVFNEGKPVFKVNKQDIFKSFSRQLDQLSHLSPGVLSQIPEEVRQHVKMLLSVTSNVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVVVYRILPALMSEFVNP-DMVPFILPNVLLIAEECTKEEYVRLVLPDLTPVFKMQE--PVQILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRAVEAPSVQIQELCLNIIPTFANLIEYPSMKNSLIPRIKSTCLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGILGIYK 551 HSP 2 Score: 53.9138 bits (128), Expect = 1.698e-60 Identity = 28/88 (31.82%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G M W+IY+ + + ++F+F+K++ ++ K K+ I D L+K + QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFEVGKHIASGGPGMSWRIYNGTKKSTKQEVAVFVFDKKVIDRYQK-FEKDQIIDSLKKGIQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: scyl1 (SCY1-like, kinase-like 1 [Source:ZFIN;Acc:ZDB-GENE-030131-8915]) HSP 1 Score: 53.5286 bits (127), Expect = 1.136e-6 Identity = 60/232 (25.86%), Postives = 98/232 (42.24%), Query Frame = 3
Query: 603 KKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLD-YIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLF-----SLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFP 1280
+K +DLE+ G++Q+ L +L + H+N+ V + +G WK+ G VTS + IT PK+ PDL+ Y PE G + D++ LG LI + G SL A+ S L KI P+ LV +++ + RPN F S + ++ + S + + K EK F Q L E + +P++ ++ P
Sbjct: 107 EKGGASDLEVSWGLHQIVKALSFLVNDCHLNHNNLGMWAVFVDRAGEWKLGGLDHVTSEQG---DSIT-----LPPPKVINPDLERYDPPESPNSGGEKWTGDVWRLGCLIWEVFNG--SLPRASSLRS--LGKI--------------PKQLVPHYCELVGANPKIRPNPARFLLNCRSPGGFMNNSFVESCLFLEEIQIKEPAEKQQFFQDLSENLDSFPEDFCKHKVLP 312
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: aurka (aurora kinase A [Source:ZFIN;Acc:ZDB-GENE-040801-161]) HSP 1 Score: 51.2174 bits (121), Expect = 3.398e-6 Identity = 41/163 (25.15%), Postives = 70/163 (42.94%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDL----DYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQL 1118
I +L D LRY H S+ VIH ++ P +L+ +G E +I D WS P + L DY+ PE+ G +D++SLG+L C + G+ K EE +++ S + P + ++N+ +++ P +L
Sbjct: 242 IMELADALRYCH-SKAVIHRDIKPENLLLGANG-----------------ELKIADFGWSVHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVL-CYEFLVGRPPFET--------KSHEETYRKISRVEFTYPAHVSNGSRDLINRLLKHNPMHRL 377
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: gatad2b (GATA zinc finger domain containing 2B [Source:Xenbase;Acc:XB-GENE-5995517]) HSP 1 Score: 201.445 bits (511), Expect = 3.144e-60 Identity = 118/455 (25.93%), Postives = 247/455 (54.29%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDM--QWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG+ L I++HKL D E K+G+ Q+++ L +LH+S ++IH+N+ P +++ +SG WK+ G F TN ++++ + +W P + P+ +Y+APE L + DM+SLG++I Y GK++ NK ++ +++++L + ++ +P+ + E V+ +LN RP++ + + +FDD+ ++++ + ++ + +K F + LP+++ + PK ++ RI P + D+ ++ + T +++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGSWDNLPSPLPPEIREHKLFDAEAKYGLLQVSEGLSFLHSSVKMIHANLTPENIILNKSGAWKIMGFDFCNPATNPSDQEAKFVCKEWDPNLPPLCLPNPEYLAPEYILSVSCDPASDMYSLGVIIHAVYNKGKTIFEVNKQDIYKSFSRQLDQLSRLNPNVLVNIPEEVKEHVKLLLNVTSTVRPDADQMTKIPFFDDVGVVTLQYFDSLFQQDNLQKSQFFKELPKVLQKLPKRVVVQRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYTKLILPDLGPVFRQQE--PIQILLIFLQKMDLLLTKTPPDEIRNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDELLPFLQQIPSREPAVLMGILGIYK 551 HSP 2 Score: 52.7582 bits (125), Expect = 3.144e-60 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G + WKI++ + + ++F+F+K+I +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGKHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKIIDKYQK-YEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: gatad2b (GATA zinc finger domain containing 2B [Source:Xenbase;Acc:XB-GENE-5995517]) HSP 1 Score: 201.06 bits (510), Expect = 3.930e-60 Identity = 118/455 (25.93%), Postives = 247/455 (54.29%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDM--QWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG+ L I++HKL D E K+G+ Q+++ L +LH+S ++IH+N+ P +++ +SG WK+ G F TN ++++ + +W P + P+ +Y+APE L + DM+SLG++I Y GK++ NK ++ +++++L + ++ +P+ + E V+ +LN RP++ + + +FDD+ ++++ + ++ + +K F + LP+++ + PK ++ RI P + D+ ++ + T +++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGSWDNLPSPLPPEIREHKLFDAEAKYGLLQVSEGLSFLHSSVKMIHANLTPENIILNKSGAWKIMGFDFCNPATNPSDQEAKFVCKEWDPNLPPLCLPNPEYLAPEYILSVSCDPASDMYSLGVIIHAVYNKGKTIFEVNKQDIYKSFSRQLDQLSRLNPNVLVNIPEEVKEHVKLLLNVTSTVRPDADQMTKIPFFDDVGVVTLQYFDSLFQQDNLQKSQFFKELPKVLQKLPKRVVVQRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYTKLILPDLGPVFRQQE--PIQILLIFLQKMDLLLTKTPPDEIRNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDELLPFLQQIPSREPAVLMGILGIYK 551 HSP 2 Score: 52.7582 bits (125), Expect = 3.930e-60 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G + WKI++ + + ++F+F+K+I +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGKHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKIIDKYQK-YEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: gatad2b (GATA zinc finger domain containing 2B [Source:Xenbase;Acc:XB-GENE-5995517]) HSP 1 Score: 201.06 bits (510), Expect = 4.382e-60 Identity = 119/459 (25.93%), Postives = 249/459 (54.25%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDM--QWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTII----LQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG+ L I++HKL D E K+G+ Q+++ L +LH+S ++IH+N+ P +++ +SG WK+ G F TN ++++ + +W P + P+ +Y+APE L + DM+SLG++I Y GK++ NK ++ +++++L + ++ +P+ + E V+ +LN RP++ + + +FDD+ ++++ + ++ + +K F + LP+++ + PK ++ RI P + D+ ++ + T +++ + P + + + + I S +I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGSWDNLPSPLPPEIREHKLFDAEAKYGLLQVSEGLSFLHSSVKMIHANLTPENIILNKSGAWKIMGFDFCNPATNPSDQEAKFVCKEWDPNLPPLCLPNPEYLAPEYILSVSCDPASDMYSLGVIIHAVYNKGKTIFEVNKQDIYKSFSRQLDQLSRLNPNVLVNIPEEVKEHVKLLLNVTSTVRPDADQMTKIPFFDDVGVVTLQYFDSLFQQDNLQKSQFFKELPKVLQKLPKRVVVQRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYTKLILPDLGPVFRQQE--PIQASNMILLIFLQKMDLLLTKTPPDEIRNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDELLPFLQQIPSREPAVLMGILGIYK 555 HSP 2 Score: 52.373 bits (124), Expect = 4.382e-60 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G + WKI++ + + ++F+F+K+I +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGKHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKIIDKYQK-YEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: gatad2b (GATA zinc finger domain containing 2B [Source:Xenbase;Acc:XB-GENE-5995517]) HSP 1 Score: 200.675 bits (509), Expect = 5.348e-60 Identity = 119/459 (25.93%), Postives = 249/459 (54.25%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDM--QWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTII----LQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG+ L I++HKL D E K+G+ Q+++ L +LH+S ++IH+N+ P +++ +SG WK+ G F TN ++++ + +W P + P+ +Y+APE L + DM+SLG++I Y GK++ NK ++ +++++L + ++ +P+ + E V+ +LN RP++ + + +FDD+ ++++ + ++ + +K F + LP+++ + PK ++ RI P + D+ ++ + T +++ + P + + + + I S +I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGSWDNLPSPLPPEIREHKLFDAEAKYGLLQVSEGLSFLHSSVKMIHANLTPENIILNKSGAWKIMGFDFCNPATNPSDQEAKFVCKEWDPNLPPLCLPNPEYLAPEYILSVSCDPASDMYSLGVIIHAVYNKGKTIFEVNKQDIYKSFSRQLDQLSRLNPNVLVNIPEEVKEHVKLLLNVTSTVRPDADQMTKIPFFDDVGVVTLQYFDSLFQQDNLQKSQFFKELPKVLQKLPKRVVVQRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYTKLILPDLGPVFRQQE--PIQASNMILLIFLQKMDLLLTKTPPDEIRNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDELLPFLQQIPSREPAVLMGILGIYK 555 HSP 2 Score: 52.7582 bits (125), Expect = 5.348e-60 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G + WKI++ + + ++F+F+K+I +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGKHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKIIDKYQK-YEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: gatad2b (GATA zinc finger domain containing 2B [Source:Xenbase;Acc:XB-GENE-5995517]) HSP 1 Score: 200.675 bits (509), Expect = 6.001e-60 Identity = 119/459 (25.93%), Postives = 249/459 (54.25%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDM--QWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTII----LQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG+ L I++HKL D E K+G+ Q+++ L +LH+S ++IH+N+ P +++ +SG WK+ G F TN ++++ + +W P + P+ +Y+APE L + DM+SLG++I Y GK++ NK ++ +++++L + ++ +P+ + E V+ +LN RP++ + + +FDD+ ++++ + ++ + +K F + LP+++ + PK ++ RI P + D+ ++ + T +++ + P + + + + I S +I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGSWDNLPSPLPPEIREHKLFDAEAKYGLLQVSEGLSFLHSSVKMIHANLTPENIILNKSGAWKIMGFDFCNPATNPSDQEAKFVCKEWDPNLPPLCLPNPEYLAPEYILSVSCDPASDMYSLGVIIHAVYNKGKTIFEVNKQDIYKSFSRQLDQLSRLNPNVLVNIPEEVKEHVKLLLNVTSTVRPDADQMTKIPFFDDVGVVTLQYFDSLFQQDNLQKSQFFKELPKVLQKLPKRVVVQRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYTKLILPDLGPVFRQQE--PIQASNMILLIFLQKMDLLLTKTPPDEIRNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDELLPFLQQIPSREPAVLMGILGIYK 555 HSP 2 Score: 52.7582 bits (125), Expect = 6.001e-60 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G + WKI++ + + ++F+F+K+I +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGKHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKIIDKYQK-YEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Scyl2 (SCY1-like 2 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1289172]) HSP 1 Score: 209.149 bits (531), Expect = 5.466e-62 Identity = 120/455 (26.37%), Postives = 248/455 (54.51%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LGN L S + IK +KL D+E K+G+ Q+++ L +LH+S +++H NV P V++ +SG WK+ G F S++N +E++ +W P + P+ +Y+APE L + DM+SLG ++ + G+ + NK ++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNVTPENVILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNQGRPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTSIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNP-DMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQE--PIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYK 551 HSP 2 Score: 50.0618 bits (118), Expect = 5.466e-62 Identity = 27/88 (30.68%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G + WKI++ + + ++F+F+K++ +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQK-FEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Scyl2 (SCY1-like 2 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1289172]) HSP 1 Score: 209.149 bits (531), Expect = 6.241e-62 Identity = 120/455 (26.37%), Postives = 248/455 (54.51%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LGN L S + IK +KL D+E K+G+ Q+++ L +LH+S +++H NV P V++ +SG WK+ G F S++N +E++ +W P + P+ +Y+APE L + DM+SLG ++ + G+ + NK ++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNVTPENVILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNQGRPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTSIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNP-DMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQE--PIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYK 551 HSP 2 Score: 50.0618 bits (118), Expect = 6.241e-62 Identity = 27/88 (30.68%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G + WKI++ + + ++F+F+K++ +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQK-FEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Scyl2 (SCY1-like 2 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1289172]) HSP 1 Score: 79.337 bits (194), Expect = 9.133e-16 Identity = 55/274 (20.07%), Postives = 142/274 (51.82%), Query Frame = 3
Query: 987 NYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVI 1808
++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++
Sbjct: 2 SFSRQLDQLSRLGSSSLTSIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNP-DMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQE--PIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGIL 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 55.0694 bits (131), Expect = 4.087e-8 Identity = 39/163 (23.93%), Postives = 76/163 (46.63%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPD----LDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQL 1118
I +L+D L Y H ++VIH ++ P +L+ +G E +I+D WS P + + LDY+ PE+ P +D++ +G+L C GK ++ + Y ++I ++ +F P ++ + +++K +RY P+ +L
Sbjct: 28 IQELSDALTYCH-EKKVIHRDIKPENLLLGLNG-----------------EVKISDFGWSVHTPSLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVL-CYELLVGKPPFESSTSSETY-RRIRQVDFKF-------PSSVPAGAQDLISKLLRYHPSERL 163
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 54.6842 bits (130), Expect = 1.822e-7 Identity = 51/224 (22.77%), Postives = 96/224 (42.86%), Query Frame = 3
Query: 486 HPMEENNETLAFATERIIGSLANLLGNDLRL--------SQSAAQAIKKHKLTDLEIKHGIYQ-LTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPD----LDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQL 1118
H + E A R I L N +D R+ + +++H+ D + I Q L+D L Y H ++VIH ++ P +L+ +G E +I+D WS P + + LDY+ PE+ P +D++ +G+L C GK ++ + Y ++I ++ +F P ++ + +++K +RY P+ +L
Sbjct: 59 HQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCH-EKKVIHRDIKPENLLLGLNG-----------------EVKISDFGWSVHTPSLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVL-CYELLVGKPPFESSTSSETY-RRIRQVDFKF-------PSSVPAGAQDLISKLLRYHPSERL 255
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8CFE4|SCYL2_MOUSE (SCY1-like protein 2 OS=Mus musculus OX=10090 GN=Scyl2 PE=1 SV=1) HSP 1 Score: 209.149 bits (531), Expect = 3.819e-61 Identity = 120/455 (26.37%), Postives = 248/455 (54.51%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LGN L S + IK +KL D+E K+G+ Q+++ L +LH+S +++H NV P V++ +SG WK+ G F S++N +E++ +W P + P+ +Y+APE L + DM+SLG ++ + G+ + NK ++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNVTPENVILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNQGRPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTSIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNP-DMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQE--PIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYK 551 HSP 2 Score: 50.0618 bits (118), Expect = 3.819e-61 Identity = 27/88 (30.68%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G + WKI++ + + ++F+F+K++ +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQK-FEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6P3W7|SCYL2_HUMAN (SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1) HSP 1 Score: 207.994 bits (528), Expect = 9.046e-61 Identity = 119/455 (26.15%), Postives = 248/455 (54.51%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQ--ITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LGN L + IK +KL D+E K+G+ Q+++ L +LH+S +++H N+ P +++ +SG WK+ G F S+TN +E++ +W P + P+ +Y+APE L + DM+SLG ++ + GK + NK ++ +++++L + SS + +P+ + E V+ +LN RP++ + + +FDD+ +++ ++ + +K F + LP+++P+ PK ++ RI P + + D+ ++ + T ++++ + P + + + + I I LQ ++ L K ++++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ ++D+++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTNIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFV-NPDMVPFVLPNVLLIAEECTKEEYVKLILPELGPVFKQQE--PIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYK 551 HSP 2 Score: 50.0618 bits (118), Expect = 9.046e-61 Identity = 27/88 (30.68%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G + WKI++ + + ++F+F+K++ +K K K+ I D L++ V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQK-FEKDQIIDSLKRGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9P7X5|PPK32_SCHPO (Protein kinase domain-containing protein ppk32 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ppk32 PE=1 SV=1) HSP 1 Score: 142.51 bits (358), Expect = 8.131e-35 Identity = 120/467 (25.70%), Postives = 224/467 (47.97%), Query Frame = 3
Query: 471 ILKVLHPMEENNETLAFATERIIGSLANLL----GNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPEL---QLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPN--SQLFSLLK--YFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESR---DLYEICFELLMATIQASTLDQ--FLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALIT--ILENSVIIDEVIPFLNEIKTNDVEILMCVIQNY 1817
+L+V+ P+EE+ +++F T RI L + + G SA + L ++EI+ G+ Q+ D L +LH S +VIH N+ PS+V++ G WK+ G F + + + D + P Q +D++APE ++ GP + D+FS G LI + + +S+INAN L +Y K+I L+ + LP E ++ +L + + P + +F L + YF + ++ + +F EK EK+SF++SL + + +P + S +I P H+ + + L FE+ + LD F + I I++ A I Q+++ L K+ + + K++P + C + + Q ++ L ID T+ + I PK+ + L V+ + L + I L++ I+D+++P L ++KT + ++M ++ Y
Sbjct: 93 LLQVVEPLEESKSSMSFVTRRIQSMLQDFIKSSNGGFSNYGSSANGKSSGNALEEVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFSF-SQSVESARYEFNDYDFGI--PSSLQQSMDFLAPEYITHEIAGPES---DVFSFGCLIYSIFNKNQSIINANNHLLSYEKEITSLNSPTFIESKNLPS---ENLKSLLKETLAVDPKQRASMFELERSPYFTGSAIAALRFLESFPEKLPSEKVSFMESLSKNLTTFPYRIQSQKILPTLLDHLNDQKLVPSLLPCIFEI------SKGLDSSIFSSKVFTAIFPIISAANSYPERVPLCIFQYMDCLKSKLPSGEFLSKIVPFIYGCFENSSLNVQTTSIQILGTLLDIIDVTTVKSSICPKLYHSFSVTNQLDVKVAILDTFNVFINQKFLDSFAIVDKLLPVLEKVKTREPTVVMGMVTVY 544 HSP 2 Score: 28.8758 bits (63), Expect = 8.131e-35 Identity = 16/60 (26.67%), Postives = 26/60 (43.33%), Query Frame = 2
Query: 305 PWKIYDAVRLVDGMDCSLFIFEKRIAEKLHK------PRRKEVICDFLRKEVFQLQSFNH 466
PW +Y A + + S+F F+K+ L K + + + LRK+V L H
Sbjct: 31 PWTVYSASKKGTNEEVSVFTFDKKNLSTLLKRGSIDSNLKTNYVLELLRKDVSSLSRLRH 90
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q55BQ3|SCY2_DICDI (Probable inactive serine/threonine-protein kinase scy2 OS=Dictyostelium discoideum OX=44689 GN=scy2 PE=3 SV=1) HSP 1 Score: 100.523 bits (249), Expect = 1.435e-28 Identity = 104/493 (21.10%), Postives = 220/493 (44.62%), Query Frame = 3
Query: 471 ILKVLHPMEENNETLAFATERIIGSLANLLG-------NDLRLSQSAAQAIKKHKLT--DLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTS-------NTNCTEEQITDMQWSAKKPKMTQ--------PDLDYIAPELQLGGPITASIDMFSLGLLI---------------CTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVE--ILMCVIQNYKEM 1826
IL+V+ MEE + FATE I+ +L +LLG + + S + + KK T +LE+K GI+Q+ D L +L+ + +++H N++P ++ IT+ WK+ G GF S +N + + + + Q+ + P LDY+APE + D+FS+G LI + +I+ T+ +++ ++ + S A + L +P+ R + + F +F D++ ++ + N +K E K+ F + L I+ ++ + ++ I P I R +Y + ++ + + F + P I++IL ++K + +L+ + L K + + ++ ++PI + + E L + + D + ++ ++P++ + + +R A+ + L+ +E +I+D ++P L +I D IL +++ Y+ +
Sbjct: 96 ILQVVSVMEETKTHIHFATEPILATLEDLLGYYRQRKKSTVDQSSQSEEGYKKKDFTFEELELKAGIFQILDGLLFLNQTAKLLHRNISPESIFITKDLKWKLGGLGFTCSIETKEPPISNLSLQDLREYQYISGGGGGESSNNSNYILPQLDYLAPEFISQRKFETNSDLFSIGRLIFELSINLEQKALDSHLISQLPKLGVISYYNTMIEQVRRQSTMNTQRSDSAKVCTILLGDPM---------LRGDLENFIRSSFFQDVLTKTLLYLANISQKEDESKLQFFRGLLRIVQQFSPRIQNNYILPVLLSEISNDRIIYVLLPNIMSISANHVKKETFQSKVLPAISNIL-QSKEPKPEVLSCVLENLPMLLQKCSLDQIKKILLPICLGSMCGPTNEIIFQCLSTAQPIAKFFDTDMISVAVIPRLTNLCVGGFPVHIRTKAIQWFTLLVPSIEKKIIVDSLLPNLEKILAGDNSPVILQSLVETYEAL 578 HSP 2 Score: 49.6766 bits (117), Expect = 1.435e-28 Identity = 23/53 (43.40%), Postives = 32/53 (60.38%), Query Frame = 2
Query: 308 WKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
WKIY + + +CSLF+FEK++ EK+ K + VI FL+KE LQ H
Sbjct: 42 WKIYQSTKKTTNTECSLFVFEKKLYEKVSKSNLENVIT-FLKKEATTLQRLRH 93
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P53009|SCY1_YEAST (Protein kinase-like protein SCY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SCY1 PE=1 SV=1) HSP 1 Score: 108.997 bits (271), Expect = 5.983e-23 Identity = 79/279 (28.32%), Postives = 139/279 (49.82%), Query Frame = 3
Query: 471 ILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGF---VTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIA-----SILPQALVEPVEKMLNKEIRYR-PNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFP 1280
IL ++ P+EE+++ F TE + SL + Q+ Q H ++ ++ GI QL + L ++H +H N+ P + I E+ WK+ G G+ + TN +E + Q+ + P L+Y APE+ +T D FSLGLLI Y GK L + + S Y + + + S+++ S +PQ L + K++N++I R N L ++F D ++ +++ + + K++EEK FL+ L ++PE+P LL + P
Sbjct: 99 ILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQNFLQG---HVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLP--QYDPRVPPFMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYT-GKDLFRSENSTSEYKLEYNKFESKISTMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNFLDDLPTKNNEEKYVFLEGLVNLLPEFPPALLQKKFLP 371
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267ELE3 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022417g1 PE=4 SV=1) HSP 1 Score: 312.768 bits (800), Expect = 6.961e-103 Identity = 176/506 (34.78%), Postives = 301/506 (59.49%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEII--PEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXX--XXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDV 1973
++L++ HP+EE NE LAFATE + GSLAN LGN R++Q +K+ TDLEIKHGI+Q+ + L+YLH++Q+VIH N+N +VLIT+ G WK+ G GFV +++ + + QW+ K PKM QPDLD++AP+LQ+ G T + D+FSLGL+I + GG SL++A ++ Y +++EEL + LP L + +EKML+++ ++RP++QL S+ KYF D +LL+++G+ E K+ E+K F L + + ++PK +L R+ P ++ + DL L+ S ++F H++ + +L R K + S ++++ + L K+ +E+++ ++P++ + S Q AAL+S + + ID+ TL +ILPK K + R L +R +AL + L+ L+ I+++++PFL +I +D +I M VI YK M+ K +++ L+ + NP L+R RC ++ L+ + +++
Sbjct: 99 KLLQIWHPVEECNENLAFATEPVWGSLANFLGNHERIAQPVPSELKE-GFTDLEIKHGIHQVNEALKYLHSTQKVIHGNLNLGSVLITKRGCWKLSGLGFVEKSSS-SHDSFNFTQWTPKLPKMAQPDLDFMAPDLQIHGKATQACDIFSLGLVIHAVFNGGVSLLDARRSCQQYHRRVEELPVNLPKALTQLPCELSDLLEKMLDRDPKHRPSAQLLSMNKYFQDPLLLALEGLTTCEAKTMEQKKEFFGLLMQTMMREQFPKSILFKRVCPLIAENLQVAADLTPYVLPCLLRAAMQSGPEEFRLHLREPLLAVLRRPK--TAQTSVVLVEHTDVLVEKLDDEEIRGDLLPLVFSTLESSSATGQEAALNSFSVLQDHIDNATLRKLILPKAKSVFQRSSSLMMRMNALACLEQLMDRLDKMTILEDLLPFLLDISFSDPDIYMAVINIYKRMLTDKKFGLTYNVIATKVLPHLIPYTVNPNLRRDDFRCVMETLNAMWSRLET 600 HSP 2 Score: 93.5893 bits (231), Expect = 6.961e-103 Identity = 40/74 (54.05%), Postives = 56/74 (75.68%), Query Frame = 2
Query: 245 NPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
NP+ + F +++QTGS G E WK+ DAVR DG +CS+FIF+K+IAEKLHKP+RKE + + LR+E+ L+ F H
Sbjct: 24 NPICKLFQLRRQTGSAGQEQLWKVIDAVRHDDGKECSIFIFDKKIAEKLHKPKRKETVSEVLRREIRYLERFKH 97
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A210PE94 (SCY1-like protein 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT08501 PE=4 SV=1) HSP 1 Score: 301.597 bits (771), Expect = 5.832e-98 Identity = 169/514 (32.88%), Postives = 295/514 (57.39%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXXXXXX--XXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNS 2003
++L +LHP+EE++ +LAFATE + SLAN+LG R+ A I+ H+ D EI++GI Q+T+ L YLH +Q++H NV+P ++LIT+ G WK+ F + + + I WS K PKM QPDL+YIAPE Q DMF+LG++ICT + G LI A + YLK+++++ ++FS +A +P LVEPVEKM+NK+IRYRP +Q F LLKYF+D +L + + N + ++ + +IIP PK++L +FP + D L+ I +T +++++ + P I+ K + + IL ++ + K ++++ +V+P + + S ++AQ AAL+++ + K +DD + N++LP+ K + ++ ++V+ +AL+ + L+ L +I+DEV+PFL +I +D +I+M V+ YK M++ K +++ L+ H NP L +++L +LE++D ++ + + +
Sbjct: 92 RLLGILHPLEESHNSLAFATEPLFASLANVLGRYDRIPTPAPPEIRDHEFLDYEIQYGILQITEALCYLHAVEQMVHKNVSPQSILITKRGTWKLAALCFAETVRDGKDSVICH-PWSTKVPKMAQPDLNYIAPETQNSKYCYFLSDMFALGMVICTIFNTGVPLIEAEHNTTTYLKQLDQIPEKFSDVAHKMPLPLVEPVEKMINKDIRYRPTAQFFCLLKYFNDPILRGLQQLDNIDIMEYCQRAEVYSFVAQIIPSIPKKILYRHVFPALCLEC-STADTITSALSPLLTLIDFATREEYVEKILPFFRLIMNSPK--PVQATVYILDKLDTVLMKSPADEIRSEVLPFVFNSLESNSLQAQEAALNAIGIIKEYLDDGVMRNMVLPRAKALYHKGSNVRVKLNALSCIDYLLDSLNKMIILDEVLPFLTDITGHDPDIVMAVVGIYKHMLSDKKFGLTHNLIATKVMPPLIPHTVNPGLSMEKFGALMEVLREMLEQIDRKRRNKMQEET 601 HSP 2 Score: 88.1965 bits (217), Expect = 5.832e-98 Identity = 40/75 (53.33%), Postives = 55/75 (73.33%), Query Frame = 2
Query: 242 NNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
+NP+++ F + +QTGS G EM WKIYDAVR D + S+ IFEK+IA+KLHKPRR+E + + LR+ V L+ F H
Sbjct: 16 SNPITKYFEIGRQTGSYGPEMVWKIYDAVRKEDKKEASVCIFEKKIADKLHKPRRRETVSEILRQGVQLLEKFKH 90
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: V4BF47 (Protein kinase domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_127669 PE=4 SV=1) HSP 1 Score: 298.901 bits (764), Expect = 1.594e-95 Identity = 173/526 (32.89%), Postives = 298/526 (56.65%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIK-----------------KHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMV---LLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXXXXXX--XXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQ 1979
+I+ + H +EE +++LAFATE I SL+N+LGN R+ + Q +K H+ D+EIK+GI+Q+T+ L +LH+S+ +IH NV P ++LIT+ G WK+ GFV + W+ K PKM QPDL++IAPE+QL T DMFSLG++IC Y GKSLI+A+ Y+K+++++H+ F +A +P LVEPVEKM+N++ RYRP +QLFS+LKYF D V L +D V + K ++ +L ++IP P+++L +FP + ++ I + D ++D + P +I++ +K + + IL ++ + K E+++ +V+P++ ++S+ ++AQ AAL + + K +DD + ++LP+ K + R +++R +ALT + ++ L +I+DEV+PFL +I D +++M V+ YK M++ K +++ SL+ H NP L +++L +LE++D ++
Sbjct: 87 KIISIQHGVEECHDSLAFATEPIFASLSNILGNYERMPANIPQELKIMQKRNIFGMRRVPFTGDHEFIDMEIKYGIFQITEALSFLHSSEHLIHRNVCPQSILITKRGAWKLASLGFVEKTKEGKKSSCQ--SWTTKIPKMAQPDLNFIAPEVQLEKICTPLSDMFSLGMVICAIYNSGKSLISADHLPGLYVKQLDQMHETFGIVAHRMPLQLVEPVEKMINRDTRYRPTAQLFSMLKYFTDPVVSGLQLLDAAVAADRKDPVQRAEAYANLSQVIPIMPRKILYRNVFPTLCQDCKSGESMV-FALPAMLTMIDFAPRDDYIDIILPEFRNIMSSSK--PVQATVYILNKLDIILSKTPLEEIKSEVLPLVFNTLDSQSLQAQEAALSAFSVIKEYLDDNIIRKMVLPRAKSLFYRSTNVRLRINALTCIDHMLDSLGKMLILDEVLPFLTDITCQDADVVMAVVGVYKHMLSDKKFGLTHNLIATKVMPSLIPHTVNPGLSMEQFGDLMEVLREMLEQIDRQR 607 HSP 2 Score: 82.8037 bits (203), Expect = 1.594e-95 Identity = 34/75 (45.33%), Postives = 54/75 (72.00%), Query Frame = 2
Query: 242 NNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
+NP+ + + +++Q G+ G E WKI++A+RL D + S+F FEK++A+KLHKPRR+E + + LRK+V QL H
Sbjct: 11 SNPILKHYDLQRQVGTAGPENVWKIFEAIRLEDSKEASVFWFEKKVADKLHKPRRRETVSEILRKDVTQLSRIRH 85
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A2R2MIZ9 (SCY1-like protein 2 isoform X6 OS=Lingula unguis OX=7574 GN=LOC106168470 PE=4 SV=1) HSP 1 Score: 297.745 bits (761), Expect = 2.536e-95 Identity = 179/529 (33.84%), Postives = 301/529 (56.90%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFL-QSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXX--XXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEI 2045
QIL+V HP+EE +++AFA+E ++ SLANLLGN R+ I+ ++EIK+GI Q+T+ L YLH ++ +H NV PS++LI++ G WK+ G GF+ + E + + W+ K KM QPDLDYIAPE+Q+ DM+S+G+ IC + GG+SL+N+ + Y K I+ L F AS LP LVEPVEKM+N++IRYRP ++LFSLLK+F D V+ + + + +K + E +F ++L + IP+ PK++L +FPF + D L+A +Q ++ +++ + I +L K + + +L+ ++ + +K E +++V+PIL ++S A+ AA+++L K +D++++ ++LP+ K I N +KV+ +AL + L+ ++ SVI D VIPFL +I+ D EI+M + ++ M+ K +Q++ SLL H N LL +D+L + + +D + + + + ET S+ I
Sbjct: 92 QILQVYHPIEECYDSVAFASEPVLASLANLLGNQERMPTPIPPEIRDFAFHEMEIKYGILQITEALSYLHNTETCLHGNVCPSSILISKRGAWKLAGMGFLQVARDGKESFMAN-PWTNKASKMVQPDLDYIAPEVQVDKRCFYVSDMYSMGITICAIHNGGRSLVNSMYNPAEYTKGIQLLSISFGDAASKLPIQLVEPVEKMINRDIRYRPTARLFSLLKFFSDSVVSCLSFLDSLPQKDAGEVTTFYTKTLVDTIPKIPKKILYQHVFPFIRDELYTESDKLVHVIPPLIAIVQNASREEYRLKLMTEINKLLAMPKNALV--TIALLEKLDIILFKTPVEAHKIQVLPILYNTLDSNNSLAREAAMNALGAIKQHLDEDSIKKMVLPRAKAIFNNANNVKVKMNALMCIDRLLDRMDKSVISDNVIPFLTKIEPEDPEIVMAITGIFRHMMTDKRCGLTHALLALQVMPSLLPHTTNALLTMEEFGVLMDLLRDMFDAIDRNRRNKMKLEAMHDDETIRGSAPNI 617 HSP 2 Score: 83.1889 bits (204), Expect = 2.536e-95 Identity = 38/78 (48.72%), Postives = 54/78 (69.23%), Query Frame = 2
Query: 245 NPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHSNPQ 478
NP+++ F + + S G EM WKIYDAVR D + S+FIF+K++A+KL+KP+RKE + + LRK V L+ F H PQ
Sbjct: 17 NPITQHFDIGRHVASAGPEMVWKIYDAVRKSDQKEASVFIFDKKVADKLYKPKRKEAVSEVLRKCVKNLERFQH--PQ 92
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A2R2MIJ0 (SCY1-like protein 2 isoform X4 OS=Lingula unguis OX=7574 GN=LOC106168470 PE=4 SV=1) HSP 1 Score: 297.745 bits (761), Expect = 2.778e-95 Identity = 179/529 (33.84%), Postives = 301/529 (56.90%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFL-QSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXX--XXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEI 2045
QIL+V HP+EE +++AFA+E ++ SLANLLGN R+ I+ ++EIK+GI Q+T+ L YLH ++ +H NV PS++LI++ G WK+ G GF+ + E + + W+ K KM QPDLDYIAPE+Q+ DM+S+G+ IC + GG+SL+N+ + Y K I+ L F AS LP LVEPVEKM+N++IRYRP ++LFSLLK+F D V+ + + + +K + E +F ++L + IP+ PK++L +FPF + D L+A +Q ++ +++ + I +L K + + +L+ ++ + +K E +++V+PIL ++S A+ AA+++L K +D++++ ++LP+ K I N +KV+ +AL + L+ ++ SVI D VIPFL +I+ D EI+M + ++ M+ K +Q++ SLL H N LL +D+L + + +D + + + + ET S+ I
Sbjct: 92 QILQVYHPIEECYDSVAFASEPVLASLANLLGNQERMPTPIPPEIRDFAFHEMEIKYGILQITEALSYLHNTETCLHGNVCPSSILISKRGAWKLAGMGFLQVARDGKESFMAN-PWTNKASKMVQPDLDYIAPEVQVDKRCFYVSDMYSMGITICAIHNGGRSLVNSMYNPAEYTKGIQLLSISFGDAASKLPIQLVEPVEKMINRDIRYRPTARLFSLLKFFSDSVVSCLSFLDSLPQKDAGEVTTFYTKTLVDTIPKIPKKILYQHVFPFIRDELYTESDKLVHVIPPLIAIVQNASREEYRLKLMTEINKLLAMPKNALV--TIALLEKLDIILFKTPVEAHKIQVLPILYNTLDSNNSLAREAAMNALGAIKQHLDEDSIKKMVLPRAKAIFNNANNVKVKMNALMCIDRLLDRMDKSVISDNVIPFLTKIEPEDPEIVMAITGIFRHMMTDKRCGLTHALLALQVMPSLLPHTTNALLTMEEFGVLMDLLRDMFDAIDRNRRNKMKLEAMHDDETIRGSAPNI 617 HSP 2 Score: 83.1889 bits (204), Expect = 2.778e-95 Identity = 36/74 (48.65%), Postives = 52/74 (70.27%), Query Frame = 2
Query: 245 NPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
NP+++ F + + S G EM WKIYDAVR D + S+FIF+K++A+KL+KP+RKE + + LRK V L+ F H
Sbjct: 17 NPITQHFDIGRHVASAGPEMVWKIYDAVRKSDQKEASVFIFDKKVADKLYKPKRKEAVSEVLRKCVKNLERFQH 90
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-244b2.1 (SCY1 like pseudokinase 2 [Source:NCBI gene;Acc:103035475]) HSP 1 Score: 207.608 bits (527), Expect = 2.014e-62 Identity = 119/455 (26.15%), Postives = 245/455 (53.85%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCT--EEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG L IK +KL D+E K+G+ Q+++ L +LH+ +++H N+ P +++ +SG WK+ G F S++N + E + +W P + P+ +Y+APE L ++ DM+SLG+++ + GK + NK ++ +++++L + + S +P + E V+ +L+ RP++ + + +FDD+ +++ + ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P +T + + + I I LQ ++ L K ED++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGQWDNLPSPVPTDIKDYKLYDVETKYGLLQISEGLSFLHSGVKMVHGNLCPENIILNKSGAWKIMGFDFSISSSNPSDAEPKYVCKEWDPNSPPLCLPNPEYVAPEYILSVSCDSASDMYSLGVVVHAVFNEGKPVFRVNKQDIFKSFSRQLDQLSRLSPGVLSKIPDEVREHVKMLLSVTANVRPDADQMTKIPFFDDVGAVTLQYFDSLFQRDNLQKSQFYKGLPKVLPKLPKRVVVYRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYVRLILPDLTPVFKQQE--PIQILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRALEAPSIQIQELCLNIIPSFANLIDYPSMKNALIPRIKSACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGILGIYK 551 HSP 2 Score: 53.1434 bits (126), Expect = 2.014e-62 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G M W+IY+ + + ++F+F+K+I ++ K K+ I D L+K V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFEVGRHIASGGPGMCWRIYNGTKKSTKQEVAVFVFDKKIVDRYQK-FEKDQIIDSLKKGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-244b2.1 (SCY1 like pseudokinase 2 [Source:NCBI gene;Acc:103035475]) HSP 1 Score: 206.838 bits (525), Expect = 2.949e-62 Identity = 120/459 (26.14%), Postives = 247/459 (53.81%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCT--EEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTII----LQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SLAN+LG L IK +KL D+E K+G+ Q+++ L +LH+ +++H N+ P +++ +SG WK+ G F S++N + E + +W P + P+ +Y+APE L ++ DM+SLG+++ + GK + NK ++ +++++L + + S +P + E V+ +L+ RP++ + + +FDD+ +++ + ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P +T + + + I S +I LQ ++ L K ED++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGQWDNLPSPVPTDIKDYKLYDVETKYGLLQISEGLSFLHSGVKMVHGNLCPENIILNKSGAWKIMGFDFSISSSNPSDAEPKYVCKEWDPNSPPLCLPNPEYVAPEYILSVSCDSASDMYSLGVVVHAVFNEGKPVFRVNKQDIFKSFSRQLDQLSRLSPGVLSKIPDEVREHVKMLLSVTANVRPDADQMTKIPFFDDVGAVTLQYFDSLFQRDNLQKSQFYKGLPKVLPKLPKRVVVYRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYVRLILPDLTPVFKQQE--PIQASNMILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRALEAPSIQIQELCLNIIPSFANLIDYPSMKNALIPRIKSACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGILGIYK 555 HSP 2 Score: 53.1434 bits (126), Expect = 2.949e-62 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G M W+IY+ + + ++F+F+K+I ++ K K+ I D L+K V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFEVGRHIASGGPGMCWRIYNGTKKSTKQEVAVFVFDKKIVDRYQK-FEKDQIIDSLKKGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-244b2.1 (SCY1 like pseudokinase 2 [Source:NCBI gene;Acc:103035475]) HSP 1 Score: 204.912 bits (520), Expect = 1.356e-61 Identity = 117/451 (25.94%), Postives = 243/451 (53.88%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCT--EEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT--LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVI 1808
++L V HP+EE+ + LAF TE + SLAN+LG L IK +KL D+E K+G+ Q+++ L +LH+ +++H N+ P +++ +SG WK+ G F S++N + E + +W P + P+ +Y+APE L ++ DM+SLG+++ + GK + NK ++ +++++L + + S +P + E V+ +L+ RP++ + + +FDD+ +++ + ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P +T + + + I I LQ ++ L K ED++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLANVLGQWDNLPSPVPTDIKDYKLYDVETKYGLLQISEGLSFLHSGVKMVHGNLCPENIILNKSGAWKIMGFDFSISSSNPSDAEPKYVCKEWDPNSPPLCLPNPEYVAPEYILSVSCDSASDMYSLGVVVHAVFNEGKPVFRVNKQDIFKSFSRQLDQLSRLSPGVLSKIPDEVREHVKMLLSVTANVRPDADQMTKIPFFDDVGAVTLQYFDSLFQRDNLQKSQFYKGLPKVLPKLPKRVVVYRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYVRLILPDLTPVFKQQE--PIQILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRALEAPSIQIQELCLNIIPSFANLIDYPSMKNALIPRIKSACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGIL 547 HSP 2 Score: 53.1434 bits (126), Expect = 1.356e-61 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V + S G M W+IY+ + + ++F+F+K+I ++ K K+ I D L+K V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFEVGRHIASGGPGMCWRIYNGTKKSTKQEVAVFVFDKKIVDRYQK-FEKDQIIDSLKKGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: aurka (aurora kinase C-like [Source:NCBI gene;Acc:103034578]) HSP 1 Score: 51.9878 bits (123), Expect = 1.584e-6 Identity = 41/163 (25.15%), Postives = 70/163 (42.94%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDL----DYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQL 1118
I +L D L Y H S++VIH ++ P +L+ +G E +I D WS P + L DY+ PE+ G +D++SLG+L C + G+ K EE +++ S + P + E ++N +++ P +L
Sbjct: 212 IMELADALHYCH-SKKVIHRDIKPENLLLGANG-----------------ELKIADFGWSVHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVL-CYEFLVGRPPFET--------KSHEETYRKISRVEFTYPAHVSEGSRNLINGLLKHNPMHRL 347
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: aurka (aurora kinase C-like [Source:NCBI gene;Acc:103034578]) HSP 1 Score: 51.2174 bits (121), Expect = 2.919e-6 Identity = 41/163 (25.15%), Postives = 70/163 (42.94%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDL----DYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQL 1118
I +L D L Y H S++VIH ++ P +L+ +G E +I D WS P + L DY+ PE+ G +D++SLG+L C + G+ K EE +++ S + P + E ++N +++ P +L
Sbjct: 258 IMELADALHYCH-SKKVIHRDIKPENLLLGANG-----------------ELKIADFGWSVHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVL-CYEFLVGRPPFET--------KSHEETYRKISRVEFTYPAHVSEGSRNLINGLLKHNPMHRL 393
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003368.1 (pep scaffold:Pmarinus_7.0:GL479057:9948:36045:-1 gene:ENSPMAG00000003073.1 transcript:ENSPMAT00000003368.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 192.2 bits (487), Expect = 1.445e-57 Identity = 113/456 (24.78%), Postives = 239/456 (52.41%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQI--TDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKT---LSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SL+N+LG L I+ H+L D+E K+G+ QL + L +LH +++H N+ P +++ ++G WK+ G F S++N +E ++ T +W P M QP ++++APE L + DM+SLG+L+ + G+ + + T ++ + +++L S+ +P+ + + ++ +LN RP++ + + YFDD+ +++ + + ++ + +K F + L +++ + PK ++ R+ P + D+ ++ + T ++++ + P + + + I I LQ ++ L K ED++ V+P++ + + + + Q L + F I+ ++ N ++P+IK + L VR +AL + L+ ++ ++DE++PFL +I + + +LM ++ YK
Sbjct: 103 RLLTVQHPIEESRDCLAFCTEPVFASLSNVLGQHENLPCPVPLEIRDHQLHDVETKYGLLQLAEGLSFLHNGVKMVHGNLTPENIVLNKNGAWKIMGFDFCISSSNPSEREVAFTCKEWVPDLPPMCQPRIEFLAPEYILSVSCDVASDMYSLGMLMYAVFNKGQPIFQMDGTHDMFKSFSRHLDKLSNLGPSVMQKVPEDVRDHLKMLLNVTPTVRPDADQLAKIPYFDDVGAMTLQYLDSLFQRDNLQKSQFFKGLSKVLSKLPKRVVQQRVLPSLTTEFVNP-DMVPFVLPNVLLIAEDCTKEEYVRMVLPDLIPVFKLQE--PIQVLLIFLQKMDLLLTKTPAEDIKQHVLPMIFRALEAPSTQIQELCLGIIPTFANLIEYPSMKNALIPRIKNSCLQTTSLAVRVNALVCLGKLLEHMDKWYVLDEILPFLQQIPSKEPAVLMGILGIYK 555 HSP 2 Score: 49.6766 bits (117), Expect = 1.445e-57 Identity = 26/91 (28.57%), Postives = 48/91 (52.75%), Query Frame = 2
Query: 194 TGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
T VT+ S+ +G NP++R F + + S G + WKIY + + ++F+FEK+ ++L + R+ + + L++ V QL H
Sbjct: 16 TADVTSAVSVVLG----NPVTREFEITRHVASGGPALSWKIYHGFKKSTKQEVAVFVFEKKQVDRLGRTEREHAV-EVLKRGVQQLTRLRH 101
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: SCY1 (Putative kinase; suppressor of GTPase mutant; similar to bovine rhodopsin kinase; may have a role in intracellular sterol transport [Source:SGD;Acc:S000003051]) HSP 1 Score: 108.997 bits (271), Expect = 8.616e-25 Identity = 79/279 (28.32%), Postives = 139/279 (49.82%), Query Frame = 3
Query: 471 ILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGF---VTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIA-----SILPQALVEPVEKMLNKEIRYR-PNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFP 1280
IL ++ P+EE+++ F TE + SL + Q+ Q H ++ ++ GI QL + L ++H +H N+ P + I E+ WK+ G G+ + TN +E + Q+ + P L+Y APE+ +T D FSLGLLI Y GK L + + S Y + + + S+++ S +PQ L + K++N++I R N L ++F D ++ +++ + + K++EEK FL+ L ++PE+P LL + P
Sbjct: 99 ILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQNFLQG---HVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLP--QYDPRVPPFMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYT-GKDLFRSENSTSEYKLEYNKFESKISTMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNFLDDLPTKNNEEKYVFLEGLVNLLPEFPPALLQKKFLP 371
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 48.521 bits (114), Expect = 2.764e-6 Identity = 35/115 (30.43%), Postives = 55/115 (47.83%), Query Frame = 3
Query: 660 CLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWS-AKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINAN--KTLSNYL 995
L YLH S+ +I+ ++ P +L+ ++GH K+ GF + + D+ ++ P DYIAPE+ P S+D +S G+LI G N+N KT N L
Sbjct: 198 ALEYLH-SKDIIYRDLKPENILLDKNGHIKITDFGFA--------KYVPDVTYTLCGTP-------DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENIL 296
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: SWE1 (Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate [Source:SGD;Acc:S000003723]) HSP 1 Score: 48.9062 bits (115), Expect = 3.416e-6 Identity = 34/111 (30.63%), Postives = 54/111 (48.65%), Query Frame = 3
Query: 603 KKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLIC 935
KK +L D I I +L+ LR++H S ++H ++ P+ V+IT G+ K+ G T + D + + D +YIAPE+ D+FSLGL+I
Sbjct: 546 KKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGM------ATHLPLEDKSFE------NEGDREYIAPEIISDCTYDYKADIFSLGLMIV 644
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 47.3654 bits (111), Expect = 6.581e-6 Identity = 34/114 (29.82%), Postives = 55/114 (48.25%), Query Frame = 3
Query: 660 CLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWS-AKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLK 998
L YLH S+ +I+ ++ P +L+ ++GH K+ GF + + D+ ++ P DYIAPE+ P SID +S G+LI G ++N T+ Y K
Sbjct: 197 ALEYLH-SKDIIYRDLKPENILLDKNGHIKITDFGFA--------KYVPDVTYTLCGTP-------DYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSN-TMKTYEK 293
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO42744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0J5]) HSP 1 Score: 182.57 bits (462), Expect = 8.508e-56 Identity = 117/460 (25.43%), Postives = 237/460 (51.52%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQIT--DMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEE---LHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFEL--LMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTII-LQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKE 1823
++L + H MEE+ + LAFATE I SL+N+LG + ++ D+E +G+YQL + L +LH +++ N++P ++IT++G WK+ G F +S E Q T +W + + QPDL+Y APE L S DM+SLG LI Y G + ++ + + +E+ + K +S+ S+ P +L V +L+ RP+ + + +F+++ L++ + + ++ K F +SL +++P+ P+ ++ R+ P ++ +L I F L ++ + T +++ + P + + KV + TII LQ ++ L K + ++ V+P++ + + + ++ Q L+ + F +D ++ N ++P+IK + + L VR + L ++ L+ ++I++++PFL +I + + LM ++ +K+
Sbjct: 88 RLLLIQHAMEESRDCLAFATEPIFASLSNVLGRHDNMPSPPPPEFANFEMYDVERVYGLYQLVEGLMFLHNDAKILQGNLSPENIVITKNGQWKIAGL-FFSSTPTIVEGQSTYSGCEWEPRLYPLAQPDLNYAAPEFILSRTCDTSSDMYSLGALIHAVYNKGAPPYQCDNNMTAFKRNVEQVCLMSKSHASLGSV-PGSLKSQVHSLLSMTPSLRPDCHQMAKIPFFENVAALTLQYLDSLMQRDDVAKTQFFKSLYKVMPKLPRRVVMQRVLP---QLCLQLSNLQVIPFVLPNILLITEDCTAEEYTKLILPELKPVF---KVQEPVQVTIIFLQKLDLLLSKTPKDSVRDDVLPMVFRALEASSIQIQEMVLNVIPKFASMVDYPSMKNAVIPRIKTLCLQTSSLSVRVNCLVCFGKILEHLDKYLVIEDILPFLAQIPSREAPTLMAILGIFKQ 539 HSP 2 Score: 54.299 bits (129), Expect = 8.508e-56 Identity = 24/80 (30.00%), Postives = 43/80 (53.75%), Query Frame = 2
Query: 227 IGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
+G NPL++ + V K S G + WK+++ G + SL +FEKR+ + + K R ++V+ + ++K QL H
Sbjct: 8 VGALVGNPLTKDYEVGKHVASFGPNLAWKVFEGKAKTTGQEASLVVFEKRLLDTVDK-RDRDVVLELMKKGAVQLTRLRH 86
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO35437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLH0]) HSP 1 Score: 51.9878 bits (123), Expect = 5.152e-7 Identity = 41/163 (25.15%), Postives = 68/163 (41.72%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQ----PDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQL 1118
I QL D L Y H S++VIH ++ P +L+ G K I D WS P + LDY+ PE+ G +D++S+G+L C + GK A E ++ S + P + +++K +++ PN++L
Sbjct: 152 IRQLADALAYCH-SKKVIHRDIKPENLLLNYKGDIK-----------------IADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGKEHDEKVDLWSIGVL-CYEFLVGKPPFEAEGH--------NETYRRISRVDLRFPSHVSPGARDLISKLLQHNPNNRL 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO39421 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA30]) HSP 1 Score: 48.9062 bits (115), Expect = 4.361e-6 Identity = 42/138 (30.43%), Postives = 67/138 (48.55%), Query Frame = 3
Query: 615 LTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYI-------APELQLGGP-ITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKI 1004
L D+ ++ +YQL +++H S VIH ++ PS +L+ K+ G S +N T+E A P +T DY+ APE+ L P T +DM+S+G ++ GK L + TL N ++KI
Sbjct: 109 LKDIHKRYIMYQLLKATKFIH-SGNVIHRDLKPSNLLLDSECFAKICDFGLARSVSNITQE--------AGDPSLT----DYVATRGILRAPEILLASPRYTKGVDMWSIGCILGELLL-GKPLFPGSSTL-NQIEKI 231
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: si:ch211-244b2.1 (SCY1 like pseudokinase 2 [Source:NCBI gene;Acc:101171295]) HSP 1 Score: 202.601 bits (514), Expect = 2.048e-60 Identity = 116/455 (25.49%), Postives = 246/455 (54.07%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCT--EEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANK--TLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SL+N+LG L + IK++KL D+E K+G+ Q+++ L +LH+ +++H N+ P +++ +SG WK+ G F S+TN + E + T +W P + P+ +Y+APE L ++ DM+SLG+++ + GK + NK ++ +++++L ++ +P+ + E + +L+ RP++ + + +FDD+ +++ + ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P ++ + + + I LQ ++ L K ED++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLSNVLGQWDNLPSPVPKDIKEYKLYDVETKYGLLQISEGLSFLHSGVKMVHGNLCPENIILNKSGAWKIMGFDFSISSTNPSDAEPKYTCKEWEPNLPPLCLPNPEYLAPEYILSVSCDSASDMYSLGVVMHAVFNEGKPVFQVNKHDIFKSFSRQLDQLSSMSPTVLGKIPEEVREHAKMLLSVTPNVRPDADQITKIPFFDDVGAVTLQYFDSLFQRDNLQKSQFYKGLPKVLPKLPKRVVVYRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYVRLIMPDLSPVFKLQE--PVQILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRAVEAPSIQIQELCLNIIPSFANLIDYPSMKNSLIPRIKSACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGILGIYK 551 HSP 2 Score: 51.6026 bits (122), Expect = 2.048e-60 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G + W+IY+ + + ++F+F+K++ +K K K+ I D L+K V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFEVGKHIASGGPGLCWRIYNGTKKSTKQEVAVFVFDKKMIDKYQK-FDKDQIIDSLKKGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: si:ch211-244b2.1 (SCY1 like pseudokinase 2 [Source:NCBI gene;Acc:101171295]) HSP 1 Score: 201.83 bits (512), Expect = 3.049e-60 Identity = 117/459 (25.49%), Postives = 248/459 (54.03%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCT--EEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANK--TLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTII----LQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYK 1820
++L V HP+EE+ + LAF TE + SL+N+LG L + IK++KL D+E K+G+ Q+++ L +LH+ +++H N+ P +++ +SG WK+ G F S+TN + E + T +W P + P+ +Y+APE L ++ DM+SLG+++ + GK + NK ++ +++++L ++ +P+ + E + +L+ RP++ + + +FDD+ +++ + ++ + +K F + LP+++P+ PK ++ RI P + D+ ++ + T ++++ + P ++ + + + S +I LQ ++ L K ED++ V+P++ + + + ++ Q L+ + F ID ++ N ++P+IK + L VR ++L + ++ L+ +IDE++PFL +I + + +LM ++ YK
Sbjct: 100 RLLTVQHPLEESRDCLAFCTEPVFASLSNVLGQWDNLPSPVPKDIKEYKLYDVETKYGLLQISEGLSFLHSGVKMVHGNLCPENIILNKSGAWKIMGFDFSISSTNPSDAEPKYTCKEWEPNLPPLCLPNPEYLAPEYILSVSCDSASDMYSLGVVMHAVFNEGKPVFQVNKHDIFKSFSRQLDQLSSMSPTVLGKIPEEVREHAKMLLSVTPNVRPDADQITKIPFFDDVGAVTLQYFDSLFQRDNLQKSQFYKGLPKVLPKLPKRVVVYRILPALTSEFVNP-DMVPFVLPNVLLIAEECTKEEYVRLIMPDLSPVFKLQE--PVQASNMILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRAVEAPSIQIQELCLNIIPSFANLIDYPSMKNSLIPRIKSACLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGILGIYK 555 HSP 2 Score: 51.6026 bits (122), Expect = 3.049e-60 Identity = 29/88 (32.95%), Postives = 46/88 (52.27%), Query Frame = 2
Query: 203 VTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNH 466
VT VT+ NP++R F V K S G + W+IY+ + + ++F+F+K++ +K K K+ I D L+K V QL H
Sbjct: 12 VTKVTADVTSAVMGNPVTREFEVGKHIASGGPGLCWRIYNGTKKSTKQEVAVFVFDKKMIDKYQK-FDKDQIIDSLKKGVQQLTRLRH 98
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: aurka (aurora kinase A [Source:NCBI gene;Acc:101165631]) HSP 1 Score: 50.8322 bits (120), Expect = 4.657e-6 Identity = 39/138 (28.26%), Postives = 62/138 (44.93%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDL----DYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASI 1043
I +L D L Y HT ++VIH ++ P +L+ +G E +I D WS P + L DY+ PE+ G +D++SLG+L C + GK A KT ++I + + + A+I
Sbjct: 273 IMELADALHYCHT-KKVIHRDIKPENLLLGANG-----------------ELKIADFGWSVHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVL-CYEFLVGKPPFEA-KTNDETYRRISRVEYTYPAHAAI 390
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: aurka (aurora kinase A [Source:NCBI gene;Acc:101165631]) HSP 1 Score: 50.447 bits (119), Expect = 5.333e-6 Identity = 39/138 (28.26%), Postives = 62/138 (44.93%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDL----DYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASI 1043
I +L D L Y HT ++VIH ++ P +L+ +G E +I D WS P + L DY+ PE+ G +D++SLG+L C + GK A KT ++I + + + A+I
Sbjct: 226 IMELADALHYCHT-KKVIHRDIKPENLLLGANG-----------------ELKIADFGWSVHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVL-CYEFLVGKPPFEA-KTNDETYRRISRVEYTYPAHAAI 343
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: aurka (aurora kinase A [Source:NCBI gene;Acc:101165631]) HSP 1 Score: 50.0618 bits (118), Expect = 8.089e-6 Identity = 39/138 (28.26%), Postives = 62/138 (44.93%), Query Frame = 3
Query: 642 IYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDL----DYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASI 1043
I +L D L Y HT ++VIH ++ P +L+ +G E +I D WS P + L DY+ PE+ G +D++SLG+L C + GK A KT ++I + + + A+I
Sbjct: 262 IMELADALHYCHT-KKVIHRDIKPENLLLGANG-----------------ELKIADFGWSVHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVL-CYEFLVGKPPFEA-KTNDETYRRISRVEYTYPAHAAI 379
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000078112.1 (SMESG000078112.1) HSP 1 Score: 1261.13 bits (3262), Expect = 0.000e+0 Identity = 679/681 (99.71%), Postives = 681/681 (100.00%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGXXXXXXXXXXXXXRIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRXXXXXXXXXXXXXXXXXXGKNLKIIPRNIVFSALAQSQITDE 2510
+ILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFEEKSSEEKMSFLQSLPEIIPEYPKELLSSRIFPFFFHH+MESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMINKKIKITKEQIIQIIHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGSFEEDNEFESEIERIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRLSGQQLPSSTSSSYRLNSGKNLKIIPRNIVFSALAQSQITDE
Sbjct: 51 KILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFEEKSSEEKMSFLQSLPEIIPEYPKELLSSRIFPFFFHHLMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMINKKIKITKEQIIQIIHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGSFEEDNEFESEIERIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRLSGQQLPSSTSSSYRLNSGKNLKIIPRNIVFSALAQSQITDE 731 HSP 2 Score: 90.5077 bits (223), Expect = 2.293e-18 Identity = 41/41 (100.00%), Postives = 41/41 (100.00%), Query Frame = 2
Query: 347 DCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS 469
DCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS
Sbjct: 10 DCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS 50
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000078112.1 (SMESG000078112.1) HSP 1 Score: 1259.97 bits (3259), Expect = 0.000e+0 Identity = 679/681 (99.71%), Postives = 681/681 (100.00%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGXXXXXXXXXXXXXRIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRXXXXXXXXXXXXXXXXXXGKNLKIIPRNIVFSALAQSQITDE 2510
+ILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFEEKSSEEKMSFLQSLPEIIPEYPKELLSSRIFPFFFHH+MESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMINKKIKITKEQIIQIIHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGSFEEDNEFESEIERIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRLSGQQLPSSTSSSYRLNSGKNLKIIPRNIVFSALAQSQITDE
Sbjct: 96 KILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFEEKSSEEKMSFLQSLPEIIPEYPKELLSSRIFPFFFHHLMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMINKKIKITKEQIIQIIHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGSFEEDNEFESEIERIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRLSGQQLPSSTSSSYRLNSGKNLKIIPRNIVFSALAQSQITDE 776 HSP 2 Score: 206.068 bits (523), Expect = 2.663e-55 Identity = 95/95 (100.00%), Postives = 95/95 (100.00%), Query Frame = 2
Query: 185 MLKTGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS 469
MLKTGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS
Sbjct: 1 MLKTGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS 95
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000078112.1 (SMESG000078112.1) HSP 1 Score: 1259.97 bits (3259), Expect = 0.000e+0 Identity = 679/681 (99.71%), Postives = 681/681 (100.00%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXXXXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGXXXXXXXXXXXXXRIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRXXXXXXXXXXXXXXXXXXGKNLKIIPRNIVFSALAQSQITDE 2510
+ILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFEEKSSEEKMSFLQSLPEIIPEYPKELLSSRIFPFFFHH+MESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMINKKIKITKEQIIQIIHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGSFEEDNEFESEIERIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRLSGQQLPSSTSSSYRLNSGKNLKIIPRNIVFSALAQSQITDE
Sbjct: 96 KILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQITDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFEEKSSEEKMSFLQSLPEIIPEYPKELLSSRIFPFFFHHLMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMINKKIKITKEQIIQIIHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSFESNSEQKSETNEMSSIEICDKTTGSFEEDNEFESEIERIQINLSPRFNGSDRNSSMRSSFTLGSPAMRKVSAPILRVNKNLSTAINLKSSEKSIKATAFIIGSTKEENSDYKKTSFNHHRRQTIDASMGLRLSGQQLPSSTSSSYRLNSGKNLKIIPRNIVFSALAQSQITDE 776 HSP 2 Score: 206.068 bits (523), Expect = 3.344e-55 Identity = 95/95 (100.00%), Postives = 95/95 (100.00%), Query Frame = 2
Query: 185 MLKTGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS 469
MLKTGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS
Sbjct: 1 MLKTGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFNHS 95
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000028722.1 (SMESG000028722.1) HSP 1 Score: 273.863 bits (699), Expect = 3.393e-89 Identity = 180/511 (35.23%), Postives = 293/511 (57.34%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKH-KLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQI-TDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXX-XXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSF 1991
+ILK+++ +EE ++ +AFATE + GSL+NLL + S+S A K+ +LT+LE K GIYQ+T+ LRYLHTSQ IH N+ P ++LIT++G WK+ G F+ + I W+ K P + QPDLDY+APE G +S DMFSLG+LI + Y GKSLI++N L+ Y +I++LH+ F+ + +P+ LVEPVEKM+NK+IRYRP+SQLFSLLKYF+D +L+++ + + KS EEK SL II ++ + L + ++P F + +Y + + A I+ + P IT H T+I K T +++ ++PI V C++ I+EAQI A++++ + +++ + +PKIK ++ +K KV+ A+ +++ L+ IL +I E + ++ + +IL C+++ Y+EM+N + I + II SLL N L ++LH++L+++ E+ S
Sbjct: 110 KILKIMYSIEETSDEIAFATEPLRGSLSNLLNSTTYQSKSKASNQKEVIELTELEKKLGIYQITEGLRYLHTSQLYIHGNITPKSILITKNGDWKLAGLNFMDRIFPGQMDNIPKGSSWNPKIPNLCQPDLDYLAPECIGIGSSNSSSDMFSLGILILSIYNDGKSLIHSNNNLNEYHVQIDKLHESFNRVVDKIPKELVEPVEKMINKDIRYRPSSQLFSLLKYFNDRRILTLESLSTMDNKSFEEKRDLFISLSGIIDQFEERFLVNHLYPVLFEKLQTCNVVYGEIVDSIAAIIKYQYM--------PWIT-----------HGKTVI--------SKSTEKEIYQDIIPIWVSCLDFVILEAQICAIENVSHYLPYLEEIFIREKFIPKIKSMIVNKKSTKVQSIAIHSINQLLPILSPQIINQEFLVIFKDLNLENPDILKCILELYQEMLNIQNILSAQTLATDIIQSLLPQTLNSQLNFETFNLLFEVLHIMLDRISCERGQSL 593 HSP 2 Score: 75.485 bits (184), Expect = 3.393e-89 Identity = 33/71 (46.48%), Postives = 47/71 (66.20%), Query Frame = 2
Query: 251 LSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFN 463
L R F + Q G+ G+E+ WKIY A R+ +CSLF+F+KR KLHK + +++I D R++V LQSFN
Sbjct: 37 LERYFRISDQIGTYGLELYWKIYQAYRVESNEECSLFVFDKRQVAKLHKAKHRDLIIDVARQDVLYLQSFN 107
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000028722.1 (SMESG000028722.1) HSP 1 Score: 273.863 bits (699), Expect = 4.281e-89 Identity = 180/511 (35.23%), Postives = 293/511 (57.34%), Query Frame = 3
Query: 468 QILKVLHPMEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKH-KLTDLEIKHGIYQLTDCLRYLHTSQQVIHSNVNPSTVLITESGHWKMFGTGFVTSNTNCTEEQI-TDMQWSAKKPKMTQPDLDYIAPELQLGGPITASIDMFSLGLLICTAYCGGKSLINANKTLSNYLKKIEELHKEFSSIASILPQALVEPVEKMLNKEIRYRPNSQLFSLLKYFDDMVLLSIDGIVNFXXXXXXXXMSFLQSLPEIIPEYPKELLSSRIFPFFFHHIMESRDLYEICFELLMATIQASTLDQFLDHMKPGITDILTRAKVNSIHESTIILQFVEPLFYKMTNEDMQLKVMPILVQCINSEIVEAQIAALDSLRLFKCCIDDETLNNIILPKIKFILNRRKLLKVRCSALTAMSALITILENSVIIDEVIPFLNEIKTNDVEILMCVIQNYKEMXX-XXXXXXXXXXXXXXHSLLNHLKNPLLKRPHIRCTVDILHLLLEKVDVEQMDSF 1991
+ILK+++ +EE ++ +AFATE + GSL+NLL + S+S A K+ +LT+LE K GIYQ+T+ LRYLHTSQ IH N+ P ++LIT++G WK+ G F+ + I W+ K P + QPDLDY+APE G +S DMFSLG+LI + Y GKSLI++N L+ Y +I++LH+ F+ + +P+ LVEPVEKM+NK+IRYRP+SQLFSLLKYF+D +L+++ + + KS EEK SL II ++ + L + ++P F + +Y + + A I+ + P IT H T+I K T +++ ++PI V C++ I+EAQI A++++ + +++ + +PKIK ++ +K KV+ A+ +++ L+ IL +I E + ++ + +IL C+++ Y+EM+N + I + II SLL N L ++LH++L+++ E+ S
Sbjct: 110 KILKIMYSIEETSDEIAFATEPLRGSLSNLLNSTTYQSKSKASNQKEVIELTELEKKLGIYQITEGLRYLHTSQLYIHGNITPKSILITKNGDWKLAGLNFMDRIFPGQMDNIPKGSSWNPKIPNLCQPDLDYLAPECIGIGSSNSSSDMFSLGILILSIYNDGKSLIHSNNNLNEYHVQIDKLHESFNRVVDKIPKELVEPVEKMINKDIRYRPSSQLFSLLKYFNDRRILTLESLSTMDNKSFEEKRDLFISLSGIIDQFEERFLVNHLYPVLFEKLQTCNVVYGEIVDSIAAIIKYQYM--------PWIT-----------HGKTVI--------SKSTEKEIYQDIIPIWVSCLDFVILEAQICAIENVSHYLPYLEEIFIREKFIPKIKSMIVNKKSTKVQSIAIHSINQLLPILSPQIINQEFLVIFKDLNLENPDILKCILELYQEMLNIQNILSAQTLATDIIQSLLPQTLNSQLNFETFNLLFEVLHIMLDRISCERGQSL 593 HSP 2 Score: 75.485 bits (184), Expect = 4.281e-89 Identity = 33/71 (46.48%), Postives = 47/71 (66.20%), Query Frame = 2
Query: 251 LSRSFSVKKQTGSCGVEMPWKIYDAVRLVDGMDCSLFIFEKRIAEKLHKPRRKEVICDFLRKEVFQLQSFN 463
L R F + Q G+ G+E+ WKIY A R+ +CSLF+F+KR KLHK + +++I D R++V LQSFN
Sbjct: 37 LERYFRISDQIGTYGLELYWKIYQAYRVESNEECSLFVFDKRQVAKLHKAKHRDLIIDVARQDVLYLQSFN 107 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 4
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 4
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030132 ID=SMED30030132|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2512bpback to top protein sequence of SMED30030132-orf-1 >SMED30030132-orf-1 ID=SMED30030132-orf-1|Name=SMED30030132-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=107bp MLKTGFVTNVTSLNIGQSWNNPLSRSFSVKKQTGSCGVEMPWKIYDAVRLback to top protein sequence of SMED30030132-orf-2 >SMED30030132-orf-2 ID=SMED30030132-orf-2|Name=SMED30030132-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=673bp MEENNETLAFATERIIGSLANLLGNDLRLSQSAAQAIKKHKLTDLEIKHGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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