Insulinoma-associated protein 1

Overview
NameInsulinoma-associated protein 1
Smed IDSMED30030122
Length (bp)823
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Insulinoma-associated protein 1 (SMED30030122) t-SNE clustered cells

Violin plots show distribution of expression levels for Insulinoma-associated protein 1 (SMED30030122) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030122

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30030122SMESG000047651.1 dd_Smed_v4_82867_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30030122SMESG000047651.1 dd_Smed_v4_82867_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30030122SMESG000047651.1 dd_Smed_v4_64330_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30030122SMESG000047651.1 dd_Smed_v4_64330_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30030122SMESG000047651.1 dd_Smed_v4_64330_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30030122SMESG000047651.1 dd_Smed_v6_82867_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Human
Match: INSM2 (INSM transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:17539])

HSP 1 Score: 89.7373 bits (221), Expect = 1.303e-19
Identity = 44/107 (41.12%), Postives = 61/107 (57.01%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSK------SFIKSESSLTSFNIESIINIQTNQRISDK 710
            +G F C+LC   Y     LA HRC +I+R+E+RCP+C K+F+CPANLASHRRWHKP+P           D K      S  +   ++ SF  E   N +  +R +D+
Sbjct:  260 LGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRI-ERTADQ 365
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Human
Match: INSM1 (INSM transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:6090])

HSP 1 Score: 81.2629 bits (199), Expect = 8.039e-17
Identity = 32/55 (58.18%), Postives = 42/55 (76.36%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHK 572
            +G F C+LC   Y     LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHK
Sbjct:  264 LGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHK 318
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Celegans
Match: egl-46 (C2H2 zinc finger protein EGL-46 [Source:UniProtKB/TrEMBL;Acc:G5EFY4])

HSP 1 Score: 98.5969 bits (244), Expect = 4.848e-24
Identity = 47/121 (38.84%), Postives = 68/121 (56.20%), Query Frame = 3 
Query:  234 RNKLPRLNEKLASHKSNQYSFMSNKDKIKSKNHHG------NKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK 578
            + KL +LNE   +       F+  +  +KS           ++     +VT E   ++ +IPN IG   C+LC   Y    +LA H+CP+I   E++CPDC K+F+CPANLASHRRWHKP+
Sbjct:  113 KTKLRKLNEDTVTSSPVSGMFIKEEADVKSVEELQKEADLLDETAAYVEVTEESRQKIDEIPNVIGDCICRLCKVKYEDVFKLAQHKCPRIAHEEYKCPDCDKVFSCPANLASHRRWHKPR 233
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Fly
Match: nerfin-2 (gene:FBgn0041105 transcript:FBtr0082177)

HSP 1 Score: 108.227 bits (269), Expect = 3.269e-26
Identity = 57/152 (37.50%), Postives = 81/152 (53.29%), Query Frame = 3 
Query:  360 KVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHL-LNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDH-LLD 809
            ++T E    L+ I N+IG + C+LC T+Y  A  LA HRCP+I+ IE++C +C K+FNCPANLASHRRWHKPK     +N  ++ +                +E+   +Q   R  D   D    + CH+C K       L+ H   H +LD
Sbjct:  437 EITEEAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPKAEAAGVNPAKKRV----------------VETGDLVQEATRSGDDASD--GIYPCHICGKTFRRQAYLKKHQASHQMLD 570
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Fly
Match: nerfin-2 (gene:FBgn0041105 transcript:FBtr0330083)

HSP 1 Score: 107.842 bits (268), Expect = 4.273e-26
Identity = 57/152 (37.50%), Postives = 81/152 (53.29%), Query Frame = 3 
Query:  360 KVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHL-LNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDH-LLD 809
            ++T E    L+ I N+IG + C+LC T+Y  A  LA HRCP+I+ IE++C +C K+FNCPANLASHRRWHKPK     +N  ++ +                +E+   +Q   R  D   D    + CH+C K       L+ H   H +LD
Sbjct:  437 EITEEAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPKAEAAGVNPAKKRV----------------VETGDLVQEATRSGDDASD--GIYPCHICGKTFRRQAYLKKHQASHQMLD 570
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Fly
Match: nerfin-1 (gene:FBgn0028999 transcript:FBtr0072592)

HSP 1 Score: 93.5893 bits (231), Expect = 1.946e-21
Identity = 51/148 (34.46%), Postives = 69/148 (46.62%), Query Frame = 3 
Query:  357 FKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDH 800
             ++T E   +L+ I N IG + C+LC   +  A  LA HRC  I+ +E+RCP+C K FNCPANLASHRRWHKP+      EN                      +  N    Q+  +K  + +  F C  C K       L  H + H
Sbjct:  230 VEITEETKAELAAIKNVIGDYVCRLCKIKFEDAFGLARHRCACIVLLEYRCPECGKQFNCPANLASHRRWHKPRKEASKKEN---------------------RNTTNQPEKQQQVEKKSEEELAFDCQECGKKFKRAAYLRKHQLTH 356
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Zebrafish
Match: INSM2 (INSM transcriptional repressor 2 [Source:NCBI gene;Acc:792891])

HSP 1 Score: 88.1965 bits (217), Expect = 2.014e-19
Identity = 35/79 (44.30%), Postives = 55/79 (69.62%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSES 644
            +G F C+LC   Y     LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHKP+     +  + ++++++  K+ S
Sbjct:  180 LGEFICQLCKEEYPDPFSLAQHKCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRTLSTADTKKSQLEARNLEKTSS 258
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Zebrafish
Match: insm1a (insulinoma-associated 1a [Source:NCBI gene;Acc:402941])

HSP 1 Score: 87.4261 bits (215), Expect = 2.156e-19
Identity = 35/57 (61.40%), Postives = 44/57 (77.19%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK 578
            +G F C+LC   Y     LA H+C +I+RIE+RCP+C K+F+CPANLASHRRWHKPK
Sbjct:  178 LGEFVCQLCREAYADPFSLAQHKCSRIVRIEYRCPECDKLFSCPANLASHRRWHKPK 234
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Zebrafish
Match: insm1a (insulinoma-associated 1a [Source:NCBI gene;Acc:402941])

HSP 1 Score: 87.4261 bits (215), Expect = 2.862e-19
Identity = 35/57 (61.40%), Postives = 44/57 (77.19%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK 578
            +G F C+LC   Y     LA H+C +I+RIE+RCP+C K+F+CPANLASHRRWHKPK
Sbjct:  178 LGEFVCQLCREAYADPFSLAQHKCSRIVRIEYRCPECDKLFSCPANLASHRRWHKPK 234
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Zebrafish
Match: insm1b (insulinoma-associated 1b [Source:NCBI gene;Acc:323882])

HSP 1 Score: 86.2705 bits (212), Expect = 8.218e-19
Identity = 33/57 (57.89%), Postives = 45/57 (78.95%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK 578
            +G F C+LC   Y+    LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHKP+
Sbjct:  221 LGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECEKVFSCPANLASHRRWHKPR 277
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Xenopus
Match: hoxa10 (homeobox A10 [Source:Xenbase;Acc:XB-GENE-478888])

HSP 1 Score: 92.4337 bits (228), Expect = 8.707e-21
Identity = 37/64 (57.81%), Postives = 49/64 (76.56%), Query Frame = 3 
Query:  390 SKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKP 581
            S  P  +G F C+LC   Y+    LA H+C +I+R+E+RCP+CHK+F+CPANLASHRRWHKP+P
Sbjct:  221 SSGPRPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECHKVFSCPANLASHRRWHKPRP 284
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Xenopus
Match: pfkfb3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Source:Xenbase;Acc:XB-GENE-963652])

HSP 1 Score: 85.1149 bits (209), Expect = 2.146e-18
Identity = 39/71 (54.93%), Postives = 51/71 (71.83%), Query Frame = 3 
Query:  372 ECHNQ--LSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK 578
            EC ++  L K P  +G F C+LC   Y     LA H+C +I+R+E+RCP+C KIF+CPANLASHRRWHKP+
Sbjct:  157 ECKSRSPLGKRPP-LGEFICQLCKEQYPDPFALAQHKCSRIVRVEYRCPECDKIFSCPANLASHRRWHKPR 226
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Xenopus
Match: stk31 (serine/threonine kinase 31 [Source:Xenbase;Acc:XB-GENE-983236])

HSP 1 Score: 52.7582 bits (125), Expect = 2.860e-7
Identity = 65/265 (24.53%), Postives = 104/265 (39.25%), Query Frame = 3 
Query:   57 SPQISYPIQSQLQVAMNWFRLIHQIRSIPQTTHIPQLSSTVELVD-KRIKHKSLKILYQNRNKLPRLNEKLASHKSNQYSFMSNKDKIKSKNHHGNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSF-IKSESSLTSF----------NIESIINIQTNQRI--SDKPLDMKADFLCHLCSKPLVNLEELENHMIDHLLD 809
             PQI + ++  +++A                 H P+LS +V  +D   +   SL++  Q ++        LA+ +  Q  F +  + +      G +   T  +T +C  Q + I  R  PFEC  C   Y   I L  H+    +     C  C K F+  ANL  H+R H  K   + NE  +    KSF +K + S T             + S  ++ T+ +I   +KP      F C  C K       L +HM  H  +
Sbjct:    2 GPQIGHSVEECVRLAQ----------------HKPRLSRSVTHIDWLDVGKASLRMDTQGKD--------LANKECGQ-DFGTEPNPLT-----GTECGETSSLTKDCQGQRN-ISTRKKPFECTKCGKGYVSRIALLTHQKSHTVGKPFTCTKCGKSFHRKANLLCHQRVHSKKKPFICNECGKRFSQKSFLVKHQKSHTGERNVTCPECGKTLSSSGSLHTHLKIHTGEKP------FTCTECGKGFTQKNNLVSHMYIHTGE 229
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Xenopus
Match: stk31 (serine/threonine kinase 31 [Source:Xenbase;Acc:XB-GENE-983236])

HSP 1 Score: 51.2174 bits (121), Expect = 9.495e-7
Identity = 48/171 (28.07%), Postives = 68/171 (39.77%), Query Frame = 3 
Query:  336 GNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSF-IKSESSLTSF----------NIESIINIQTNQRI--SDKPLDMKADFLCHLCSKPLVNLEELENHMIDHLLD 809
            G +   T  +T +C  Q + I  R  PFEC  C   Y   I L  H+    +     C  C K F+  ANL  H+R H  K   + NE  +    KSF +K + S T             + S  ++ T+ +I   +KP      F C  C K       L +HM  H  +
Sbjct:   26 GTECGETSSLTKDCQGQRN-ISTRKKPFECTKCGKGYVSRIALLTHQKSHTVGKPFTCTKCGKSFHRKANLLCHQRVHSKKKPFICNECGKRFSQKSFLVKHQKSHTGERNVTCPECGKTLSSSGSLHTHLKIHTGEKP------FTCTECGKGFTQKNNLVSHMYIHTGE 189
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Xenopus
Match: stk31 (serine/threonine kinase 31 [Source:Xenbase;Acc:XB-GENE-983236])

HSP 1 Score: 51.2174 bits (121), Expect = 1.019e-6
Identity = 48/171 (28.07%), Postives = 68/171 (39.77%), Query Frame = 3 
Query:  336 GNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSF-IKSESSLTSF----------NIESIINIQTNQRI--SDKPLDMKADFLCHLCSKPLVNLEELENHMIDHLLD 809
            G +   T  +T +C  Q + I  R  PFEC  C   Y   I L  H+    +     C  C K F+  ANL  H+R H  K   + NE  +    KSF +K + S T             + S  ++ T+ +I   +KP      F C  C K       L +HM  H  +
Sbjct:  174 GTECGETSSLTKDCQGQRN-ISTRKKPFECTKCGKGYVSRIALLTHQKSHTVGKPFTCTKCGKSFHRKANLLCHQRVHSKKKPFICNECGKRFSQKSFLVKHQKSHTGERNVTCPECGKTLSSSGSLHTHLKIHTGEKP------FTCTECGKGFTQKNNLVSHMYIHTGE 337
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Mouse
Match: Insm2 (insulinoma-associated 2 [Source:MGI Symbol;Acc:MGI:1930787])

HSP 1 Score: 87.8113 bits (216), Expect = 3.130e-19
Identity = 36/65 (55.38%), Postives = 47/65 (72.31%), Query Frame = 3 
Query:  387 LSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKP 581
            L  +   +G F C+LC   Y     LA HRC +I+R+E+RCP+C K+F+CPANLASHRRWHKP+P
Sbjct:  193 LGGVRTPLGEFICQLCKHQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP 257
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Mouse
Match: Insm1 (insulinoma-associated 1 [Source:MGI Symbol;Acc:MGI:1859980])

HSP 1 Score: 81.6481 bits (200), Expect = 5.251e-17
Identity = 32/55 (58.18%), Postives = 42/55 (76.36%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHK 572
            +G F C+LC   Y     LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHK
Sbjct:  269 LGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHK 323
[Close]
BLAST of Insulinoma-associated protein 1 vs. UniProt/SwissProt
Match: sp|A7UKY7|INSM1_XENLA (Insulinoma-associated protein 1 OS=Xenopus laevis OX=8355 GN=insm1 PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 2.004e-20
Identity = 41/88 (46.59%), Postives = 57/88 (64.77%), Query Frame = 3 
Query:  390 SKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHL--LNENEEEIDSKSFIKSESS 647
            S  P  +G F C+LC   Y+    LA H+C +I+R+E+RCP+CHK+F+CPANLASHRRWHKP+P  +  +   EE +  +     ES 
Sbjct:  213 SSGPRPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECHKVFSCPANLASHRRWHKPRPPAVPAVQPKEEALSDRDTPSPESG 300
[Close]
BLAST of Insulinoma-associated protein 1 vs. UniProt/SwissProt
Match: sp|A4IHR5|INSM1_XENTR (Insulinoma-associated protein 1 OS=Xenopus tropicalis OX=8364 GN=insm1 PE=2 SV=2)

HSP 1 Score: 92.4337 bits (228), Expect = 4.524e-20
Identity = 37/64 (57.81%), Postives = 49/64 (76.56%), Query Frame = 3 
Query:  390 SKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKP 581
            S  P  +G F C+LC   Y+    LA H+C +I+R+E+RCP+CHK+F+CPANLASHRRWHKP+P
Sbjct:  221 SSGPRPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECHKVFSCPANLASHRRWHKPRP 284
[Close]
BLAST of Insulinoma-associated protein 1 vs. UniProt/SwissProt
Match: sp|Q96T92|INSM2_HUMAN (Insulinoma-associated protein 2 OS=Homo sapiens OX=9606 GN=INSM2 PE=1 SV=3)

HSP 1 Score: 89.7373 bits (221), Expect = 6.259e-19
Identity = 44/107 (41.12%), Postives = 61/107 (57.01%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSK------SFIKSESSLTSFNIESIINIQTNQRISDK 710
            +G F C+LC   Y     LA HRC +I+R+E+RCP+C K+F+CPANLASHRRWHKP+P           D K      S  +   ++ SF  E   N +  +R +D+
Sbjct:  260 LGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRI-ERTADQ 365
[Close]
BLAST of Insulinoma-associated protein 1 vs. UniProt/SwissProt
Match: sp|Q6P0F9|INS1A_DANRE (Insulinoma-associated protein 1a OS=Danio rerio OX=7955 GN=insm1a PE=2 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 2.161e-18
Identity = 35/57 (61.40%), Postives = 44/57 (77.19%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK 578
            +G F C+LC   Y     LA H+C +I+RIE+RCP+C K+F+CPANLASHRRWHKPK
Sbjct:  178 LGEFVCQLCREAYADPFSLAQHKCSRIVRIEYRCPECDKLFSCPANLASHRRWHKPK 234
[Close]
BLAST of Insulinoma-associated protein 1 vs. UniProt/SwissProt
Match: sp|Q9JMC2|INSM2_MOUSE (Insulinoma-associated protein 2 OS=Mus musculus OX=10090 GN=Insm2 PE=1 SV=2)

HSP 1 Score: 87.8113 bits (216), Expect = 2.189e-18
Identity = 36/65 (55.38%), Postives = 47/65 (72.31%), Query Frame = 3 
Query:  387 LSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKP 581
            L  +   +G F C+LC   Y     LA HRC +I+R+E+RCP+C K+F+CPANLASHRRWHKP+P
Sbjct:  193 LGGVRTPLGEFICQLCKHQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP 257
[Close]
BLAST of Insulinoma-associated protein 1 vs. TrEMBL
Match: V4B5U2 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_96643 PE=4 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 6.757e-26
Identity = 62/150 (41.33%), Postives = 80/150 (53.33%), Query Frame = 3 
Query:  360 KVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDHLLD 809
            +VT E   +L +I NRIG + C+LC   Y  A QLA HRC +I+ +E+RCP+C K+FNCPANLASHRRWHKPKP   +N N                      S I+++T Q  SD        F C  C K       L+ HM+ H+ D
Sbjct:   71 EVTPEARAELERIENRIGDYICQLCKEYYEDAFQLAQHRCSRIVHVEYRCPECDKVFNCPANLASHRRWHKPKPNKSINNNN--------------------NSAIDLRTTQ--SD-----DGHFDCQTCGKKFKRPAYLKKHMLTHVND 193
[Close]
BLAST of Insulinoma-associated protein 1 vs. TrEMBL
Match: B4N9M2 (Uncharacterized protein OS=Drosophila willistoni OX=7260 GN=Dwil\GK10878 PE=4 SV=2)

HSP 1 Score: 113.235 bits (282), Expect = 2.122e-24
Identity = 59/149 (39.60%), Postives = 84/149 (56.38%), Query Frame = 3 
Query:  360 KVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDHLL 806
            ++T E    L+ I N+IG + C+LC T+Y  A  LA HRCP+I+ IE++C +C K+FNCPANLASHRRWHKPK            DS S  +S+   ++ N    +N ++N R++D   D    + CH C K       L+ H   H +
Sbjct:  421 EITEEAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPK-----------TDSASGAQSKKRASTSNEVQNVNEESN-RVTDDASD--GIYPCHDCGKTFRRHAYLKKHQASHQM 555
[Close]
BLAST of Insulinoma-associated protein 1 vs. TrEMBL
Match: A0A4Y2ESR0 (Insulinoma-associated protein 1b OS=Araneus ventricosus OX=182803 GN=insm1b PE=4 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 3.613e-24
Identity = 67/179 (37.43%), Postives = 92/179 (51.40%), Query Frame = 3 
Query:  348 LTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK---------------PRHLLNENEEEI---DSKSFIKSES----SLTSFNIESIIN-----IQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDHL 803
            L    +T E   +L+KI N+IG + C+LC   Y  A  LA HRC +I+ +E+RCP+C K+FNCPANLASHRRWHKP+               P+ L N  E+ +   D+K  +K  S    S    + ESI +     + +N+R S    D   D  CHLC K          H++ HL
Sbjct:  264 LNVVVITDEARAELAKIENKIGDYVCQLCKEHYDDAFGLAQHRCSRIVHVEYRCPECDKVFNCPANLASHRRWHKPRPPPGMKNGAANSKNPPKLLSNSTEKTVAKADTKIPVKEGSHQGFSTDPSDTESIRDASSPELSSNRRYSTSSEDK--DLECHLCCKKFSQYFYFRKHLLSHL 440
[Close]
BLAST of Insulinoma-associated protein 1 vs. TrEMBL
Match: A0A2A3EAP5 (Insulinoma-associated protein OS=Apis cerana cerana OX=94128 GN=APICC_09487 PE=4 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 5.485e-24
Identity = 44/73 (60.27%), Postives = 57/73 (78.08%), Query Frame = 3 
Query:  360 KVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK 578
            +VT E   +L+KI NR+GP++CKLC  L+  A QLA HRC +I  +E+RCP+C K F+CPANLASHRRWHKP+
Sbjct: 1627 EVTEEARAELAKIENRLGPYQCKLCRQLHEDAFQLAQHRCSRIAHVEYRCPECDKRFSCPANLASHRRWHKPR 1699
[Close]
BLAST of Insulinoma-associated protein 1 vs. TrEMBL
Match: A0A0L0CLH0 (Uncharacterized protein OS=Lucilia cuprina OX=7375 GN=FF38_03643 PE=4 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 5.851e-24
Identity = 64/149 (42.95%), Postives = 80/149 (53.69%), Query Frame = 3 
Query:  360 KVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKAD--FLCHLCSKPLVNLEELENHMIDH 800
            +VT E    L+ I N+IG + C+LC TLY  A +LA HRCP+I+ IE++C +C K+FNCPANLASHRRWHKPK   L N       SK    +E            N QT    SDK +D   D  F C+ C K       L+ H   H
Sbjct:  478 EVTEEAKAILASIDNKIGAYLCQLCRTLYDDAFKLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPKSEILANSQ-----SKKRAHAER-----------NSQTGSNSSDK-IDDGVDGIFPCNQCGKTFRRHAYLKKHQASH 609
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Cavefish
Match: insm1a (insulinoma-associated 1a [Source:NCBI gene;Acc:402941])

HSP 1 Score: 92.4337 bits (228), Expect = 4.628e-21
Identity = 49/150 (32.67%), Postives = 73/150 (48.67%), Query Frame = 3 
Query:  357 FKVTSECHNQLSKIPNR--IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDH 800
             K   E H++   +  +  +G F C+LC   Y     LA HRC +I+R+E+RCP+C K+F+CPANLASHRRWHKPKP       E+        K+ SS +  +         +  +S+   +      C  C +       L  H++ H
Sbjct:  178 IKEAPEGHDEGRAVQQKQSLGEFVCQLCREAYADPFALAQHRCSRIVRVEYRCPECEKVFSCPANLASHRRWHKPKPPSAGQGQEQGGHVGQGSKTSSSESDRDT-------VSPGLSESGSEEDGACECQHCGRRFKRHAYLRKHVLAH 320
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Cavefish
Match: insm1b (insulinoma-associated 1b [Source:NCBI gene;Acc:323882])

HSP 1 Score: 85.8853 bits (211), Expect = 1.043e-18
Identity = 38/84 (45.24%), Postives = 52/84 (61.90%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSF 659
            +G F C+LC   Y     LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHKP+ +        E       K  S+L +F
Sbjct:  254 LGEFICQLCKEEYADPFSLAQHKCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRAQAQAGTKGSEAS-----KPSSALRAF 332
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Cavefish
Match: ENSAMXT00000025908.2 (insulinoma-associated protein 1a-like [Source:NCBI gene;Acc:103046881])

HSP 1 Score: 83.9593 bits (206), Expect = 3.877e-18
Identity = 35/69 (50.72%), Postives = 49/69 (71.01%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEI 614
            +G F C+LC   Y   + LA+H+C +I+R+E+RC +C K F+CPANLASHRRWHKPK    L++ E  +
Sbjct:  197 LGEFMCQLCKERYPDPLSLAHHKCSRIVRVEYRCDECDKAFSCPANLASHRRWHKPKGAAGLSDAESRL 265
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Sea Lamprey
Match: insm1b (insulinoma-associated 1b [Source:NCBI gene;Acc:323882])

HSP 1 Score: 88.1965 bits (217), Expect = 3.370e-20
Identity = 34/57 (59.65%), Postives = 44/57 (77.19%), Query Frame = 3 
Query:  411 GPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKP 581
            G + C+LC   Y     LA HRC +I+R+E+RCP+C K+F+CPANLASHRRWHKP+P
Sbjct:  211 GGYVCQLCKEEYGDPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP 267
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Nematostella
Match: EDO35669 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKS6])

HSP 1 Score: 70.0922 bits (170), Expect = 6.034e-15
Identity = 40/131 (30.53%), Postives = 65/131 (49.62%), Query Frame = 3 
Query:  417 FECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDHLLD 809
            F C+LC+ +Y+    LA H+C  I   EHRCP+C K+F+CPANLASHRR         +  ++ +     F+ +  + T F  ++ +    N    D+P      + C  C K   +L     H+++H + 
Sbjct:    4 FICQLCSEVYSDPFSLAQHKCSGIQHTEHRCPECDKVFSCPANLASHRR--------PVGSSQGQ-----FVCTVCNKT-FRRKAYLRKHMNNHTDDRP------YPCQYCGKVFRSLTNRAKHVLNHAVG 114
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Medaka
Match: insm1a (INSM transcriptional repressor 1 [Source:NCBI gene;Acc:101163626])

HSP 1 Score: 90.1225 bits (222), Expect = 3.801e-20
Identity = 35/59 (59.32%), Postives = 46/59 (77.97%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPR 584
            +G F C+LC   Y     LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHKPKP+
Sbjct:  218 LGEFVCQLCREAYADPFSLAQHKCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPKPQ 276
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Medaka
Match: INSM2 (INSM transcriptional repressor 2 [Source:NCBI gene;Acc:101159149])

HSP 1 Score: 88.9669 bits (219), Expect = 1.208e-19
Identity = 49/144 (34.03%), Postives = 76/144 (52.78%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQ-------TNQRISDKP----LDMKADFLCHLCSKPLVNLEELENHMIDHLL 806
            +G F C+LC   Y     LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHKP+P  ++++  E    ++     SSL   N +             T+  +S+ P    L  +  + C  C K       L+ H++ H +
Sbjct:  282 LGEFICQLCKEEYPDPFSLAQHKCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP--VISQGVETNRMRAADSPPSSLLLRNGDPHERADVLPPPSLTHPHLSNPPFIQALTEEEVYECRYCGKKFRRQAYLKKHLVTHEM 423
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Medaka
Match: insm1b (insulinoma-associated protein 1b [Source:NCBI gene;Acc:101161355])

HSP 1 Score: 86.6557 bits (213), Expect = 3.938e-19
Identity = 42/131 (32.06%), Postives = 62/131 (47.33%), Query Frame = 3 
Query:  408 IGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDH 800
            +G F C+LC   Y     LA H+C +I+R+E+RCP+C K+F+CPANLASHRRWHKP                   ++ S   S   + + + +T      +       + C  C K       L  H++ H
Sbjct:  176 LGEFVCQLCKEAYADPFSLAQHKCSRIVRVEYRCPECDKMFSCPANLASHRRWHKP-------------------RTTSGAPSDEAKDMSDRETPSPGPSESGSEDGSYDCQYCGKRFKRQAYLRKHIMGH 287
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Medaka
Match: ZNF574 (zinc finger protein 574 [Source:NCBI gene;Acc:101174294])

HSP 1 Score: 48.1358 bits (113), Expect = 5.540e-6
Identity = 40/157 (25.48%), Postives = 65/157 (41.40%), Query Frame = 3 
Query:  372 ECHNQLSKIPNRIG---------PFECKLCATLYTGAIQLANHRCPQILRIE----HRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDHL 803
            E  +++  + NR+G         P +C+LC+ ++T   +LA H+     R+     H CP+C K+F    +L +H R H    R+L       +D           T F  E  + +     ++D PL       C  CSK   N+ +   H   HL
Sbjct:  337 ETSDKMEGMRNRVGGKRGGAWAKPLQCELCSRIFTSVNRLAAHK-----RVHEQGTHECPECGKVFKKATSLQTHMRTHSGVARYLC------VDCG---------TGFTTEMTLIMHRKSHVAD-PLHK-----CQFCSKTFTNMTKYLYHRRTHL 467
[Close]
BLAST of Insulinoma-associated protein 1 vs. Ensembl Medaka
Match: ZNF574 (zinc finger protein 574 [Source:NCBI gene;Acc:101174294])

HSP 1 Score: 48.1358 bits (113), Expect = 5.540e-6
Identity = 40/157 (25.48%), Postives = 65/157 (41.40%), Query Frame = 3 
Query:  372 ECHNQLSKIPNRIG---------PFECKLCATLYTGAIQLANHRCPQILRIE----HRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDHL 803
            E  +++  + NR+G         P +C+LC+ ++T   +LA H+     R+     H CP+C K+F    +L +H R H    R+L       +D           T F  E  + +     ++D PL       C  CSK   N+ +   H   HL
Sbjct:  337 ETSDKMEGMRNRVGGKRGGAWAKPLQCELCSRIFTSVNRLAAHK-----RVHEQGTHECPECGKVFKKATSLQTHMRTHSGVARYLC------VDCG---------TGFTTEMTLIMHRKSHVAD-PLHK-----CQFCSKTFTNMTKYLYHRRTHL 467
[Close]
BLAST of Insulinoma-associated protein 1 vs. Planmine SMEST
Match: SMESG000047651.1 (SMESG000047651.1)

HSP 1 Score: 465.307 bits (1196), Expect = 3.228e-168
Identity = 228/228 (100.00%), Postives = 228/228 (100.00%), Query Frame = 3 
Query:    3 WHNSTVCNINSNFPILNNSPQISYPIQSQLQVAMNWFRLIHQIRSIPQTTHIPQLSSTVELVDKRIKHKSLKILYQNRNKLPRLNEKLASHKSNQYSFMSNKDKIKSKNHHGNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQ 686
            WHNSTVCNINSNFPILNNSPQISYPIQSQLQVAMNWFRLIHQIRSIPQTTHIPQLSSTVELVDKRIKHKSLKILYQNRNKLPRLNEKLASHKSNQYSFMSNKDKIKSKNHHGNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQ
Sbjct:    2 WHNSTVCNINSNFPILNNSPQISYPIQSQLQVAMNWFRLIHQIRSIPQTTHIPQLSSTVELVDKRIKHKSLKILYQNRNKLPRLNEKLASHKSNQYSFMSNKDKIKSKNHHGNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQ 229
[Close]
BLAST of Insulinoma-associated protein 1 vs. Planmine SMEST
Match: SMESG000041297.1 (SMESG000041297.1)

HSP 1 Score: 104.76 bits (260), Expect = 2.961e-26
Identity = 62/174 (35.63%), Postives = 86/174 (49.43%), Query Frame = 3 
Query:  324 KNHHGNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTGAIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPK---------------PRHLLNENEEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCSKPLVNLEELENHMIDH 800
            KN      +    +T +   +L+KI N++G + C+LC   Y  A  LA H CP+I  +E+RC +C K+FNCPANLASH+RWHKPK               P  +    + E  +  F K+ ++     I  I    T    SD  L       CH+C   L + E LE+HMIDH
Sbjct:  130 KNVQSGASVPVINITEKARKELAKIQNKLGNYTCQLCHETYADAFLLAQHHCPRIRHVEYRCSECDKVFNCPANLASHKRWHKPKSPDWGVQKKPIQKISPYSIDALIDHESKTPPFFKTSNAKKFSTIPQITTSSTTVSASDLLLS------CHICGDVLPSQELLESHMIDH 297
The following BLAST results are available for this feature:
BLAST of Insulinoma-associated protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
INSM21.303e-1941.12INSM transcriptional repressor 2 [Source:HGNC Symb... [more]
INSM18.039e-1758.18INSM transcriptional repressor 1 [Source:HGNC Symb... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
egl-464.848e-2438.84C2H2 zinc finger protein EGL-46 [Source:UniProtKB... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
nerfin-23.269e-2637.50gene:FBgn0041105 transcript:FBtr0082177[more]
nerfin-24.273e-2637.50gene:FBgn0041105 transcript:FBtr0330083[more]
nerfin-11.946e-2134.46gene:FBgn0028999 transcript:FBtr0072592[more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
INSM22.014e-1944.30INSM transcriptional repressor 2 [Source:NCBI gene... [more]
insm1a2.156e-1961.40insulinoma-associated 1a [Source:NCBI gene;Acc:402... [more]
insm1a2.862e-1961.40insulinoma-associated 1a [Source:NCBI gene;Acc:402... [more]
insm1b8.218e-1957.89insulinoma-associated 1b [Source:NCBI gene;Acc:323... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hoxa108.707e-2157.81homeobox A10 [Source:Xenbase;Acc:XB-GENE-478888][more]
pfkfb32.146e-1854.936-phosphofructo-2-kinase/fructose-2,6-biphosphatas... [more]
stk312.860e-724.53serine/threonine kinase 31 [Source:Xenbase;Acc:XB-... [more]
stk319.495e-728.07serine/threonine kinase 31 [Source:Xenbase;Acc:XB-... [more]
stk311.019e-628.07serine/threonine kinase 31 [Source:Xenbase;Acc:XB-... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Insm23.130e-1955.38insulinoma-associated 2 [Source:MGI Symbol;Acc:MGI... [more]
Insm15.251e-1758.18insulinoma-associated 1 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Insulinoma-associated protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A7UKY7|INSM1_XENLA2.004e-2046.59Insulinoma-associated protein 1 OS=Xenopus laevis ... [more]
sp|A4IHR5|INSM1_XENTR4.524e-2057.81Insulinoma-associated protein 1 OS=Xenopus tropica... [more]
sp|Q96T92|INSM2_HUMAN6.259e-1941.12Insulinoma-associated protein 2 OS=Homo sapiens OX... [more]
sp|Q6P0F9|INS1A_DANRE2.161e-1861.40Insulinoma-associated protein 1a OS=Danio rerio OX... [more]
sp|Q9JMC2|INSM2_MOUSE2.189e-1855.38Insulinoma-associated protein 2 OS=Mus musculus OX... [more]
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BLAST of Insulinoma-associated protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V4B5U26.757e-2641.33Uncharacterized protein (Fragment) OS=Lottia gigan... [more]
B4N9M22.122e-2439.60Uncharacterized protein OS=Drosophila willistoni O... [more]
A0A4Y2ESR03.613e-2437.43Insulinoma-associated protein 1b OS=Araneus ventri... [more]
A0A2A3EAP55.485e-2460.27Insulinoma-associated protein OS=Apis cerana ceran... [more]
A0A0L0CLH05.851e-2442.95Uncharacterized protein OS=Lucilia cuprina OX=7375... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
insm1a4.628e-2132.67insulinoma-associated 1a [Source:NCBI gene;Acc:402... [more]
insm1b1.043e-1845.24insulinoma-associated 1b [Source:NCBI gene;Acc:323... [more]
ENSAMXT00000025908.23.877e-1850.72insulinoma-associated protein 1a-like [Source:NCBI... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
insm1b3.370e-2059.65insulinoma-associated 1b [Source:NCBI gene;Acc:323... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO356696.034e-1530.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Insulinoma-associated protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
insm1a3.801e-2059.32INSM transcriptional repressor 1 [Source:NCBI gene... [more]
INSM21.208e-1934.03INSM transcriptional repressor 2 [Source:NCBI gene... [more]
insm1b3.938e-1932.06insulinoma-associated protein 1b [Source:NCBI gene... [more]
ZNF5745.540e-625.48zinc finger protein 574 [Source:NCBI gene;Acc:1011... [more]
ZNF5745.540e-625.48zinc finger protein 574 [Source:NCBI gene;Acc:1011... [more]
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BLAST of Insulinoma-associated protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000047651.13.228e-168100.00SMESG000047651.1[more]
SMESG000041297.12.961e-2635.63SMESG000041297.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030122 ID=SMED30030122|Name=Insulinoma-associated protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=823bp
TGTGGCATAACAGTACGGTTTGCAATATCAATTCCAATTTTCCTATTTTA
AACAATTCTCCTCAAATATCATATCCAATACAGTCTCAATTACAAGTAGC
TATGAACTGGTTCCGACTGATTCATCAGATCCGATCAATTCCTCAGACAA
CTCACATTCCACAATTATCATCAACTGTTGAGCTTGTGGATAAAAGAATC
AAACACAAATCATTGAAAATATTATACCAAAACCGAAACAAGTTACCACG
TTTAAATGAAAAATTAGCATCCCACAAATCAAATCAGTATTCCTTTATGT
CTAATAAAGATAAAATCAAATCAAAAAATCATCACGGAAATAAATTTTTA
ACTACTTTCAAAGTCACATCGGAATGTCACAATCAGCTGTCAAAAATACC
CAATCGGATCGGTCCTTTTGAATGCAAACTCTGCGCAACGCTTTACACTG
GTGCAATCCAGTTGGCAAATCATCGTTGCCCGCAGATTTTAAGAATAGAG
CACAGATGTCCCGACTGTCATAAAATTTTTAATTGCCCTGCAAATCTTGC
GTCTCATAGACGATGGCACAAACCAAAACCTAGACATCTATTGAATGAAA
ACGAAGAAGAGATTGATAGTAAATCGTTCATCAAATCTGAGAGTTCTCTG
ACATCTTTCAACATAGAATCCATAATTAATATACAAACAAATCAAAGAAT
ATCAGACAAACCTCTAGACATGAAAGCAGATTTCTTGTGTCATCTCTGCT
CGAAACCTTTAGTGAACTTGGAGGAGCTGGAAAATCATATGATAGATCAT
TTATTAGACATTTGTTATCCTAG
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protein sequence of SMED30030122-orf-1

>SMED30030122-orf-1 ID=SMED30030122-orf-1|Name=SMED30030122-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=273bp
WHNSTVCNINSNFPILNNSPQISYPIQSQLQVAMNWFRLIHQIRSIPQTT
HIPQLSSTVELVDKRIKHKSLKILYQNRNKLPRLNEKLASHKSNQYSFMS
NKDKIKSKNHHGNKFLTTFKVTSECHNQLSKIPNRIGPFECKLCATLYTG
AIQLANHRCPQILRIEHRCPDCHKIFNCPANLASHRRWHKPKPRHLLNEN
EEEIDSKSFIKSESSLTSFNIESIINIQTNQRISDKPLDMKADFLCHLCS
KPLVNLEELENHMIDHLLDICYP
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0003676nucleic acid binding
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR015880Znf_C2H2-like
IPR013087Znf_C2H2_type
IPR007087Znf_C2H2