Potassium voltage-gated channel protein Shab

Overview


Name	Potassium voltage-gated channel protein Shab
Smed ID	SMED30030120
Length (bp)	815

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030120

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30030120	h1SMcG0018142	dd_Smed_v4_14610_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30030120	h1SMcG0018142	dd_Smed_v4_14610_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30030120	h1SMcG0018142	dd_Smed_v4_14610_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
body wall musculature	SMED30030120	h1SMcG0018142	dd_Smed_v4_14610_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Human
Match: KCNB1 (potassium voltage-gated channel subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:6231])

HSP 1 Score: 112.079 bits (279), Expect = 3.550e-27
Identity = 57/160 (35.62%), Postives = 86/160 (53.75%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

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Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Human
Match: KCNB2 (potassium voltage-gated channel subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:6232])

HSP 1 Score: 105.531 bits (262), Expect = 6.627e-25
Identity = 54/160 (33.75%), Postives = 84/160 (52.50%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            +NVGG   +V W+  L R    RL +L    T + +L+ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    C   R ++WDL+E P  S +A++ 
Sbjct:   39 INVGGLNHEVLWRT-LDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTC--CPDKRKKLWDLLEKPNSSVAAKIL 195

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Human
Match: KCNS1 (potassium voltage-gated channel modifier subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:6300])

HSP 1 Score: 98.9821 bits (245), Expect = 7.462e-23
Identity = 52/173 (30.06%), Postives = 89/173 (51.45%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIH-----------GRCAKLRSQIWDLMENPEKSKSAQLFK 555
             +NVGG   ++S +  L R    RL RL +A + +Q  + CDD+     E++FDRHP FF S+LH  + G  +  + +CV +   + +YWG+ +N ++ CC   Y L+  +++       +   + ++  P+ I             RC +LR ++W  MENP  S  ++LF 
Sbjct:   53 RVNVGGVRRQLSARA-LARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARY-LERRLTQPHAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFS 223

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Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIH-----------GRCAKLRSQIWDLMENPEKSKSAQLFK 555
             +NVGG   ++S +  L R    RL RL +A + +Q  + CDD+     E++FDRHP FF S+LH  + G  +  + +CV +   + +YWG+ +N ++ CC   Y L+  +++       +   + ++  P+ I             RC +LR ++W  MENP  S  ++LF 
Sbjct:   53 RVNVGGVRRQLSARA-LARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARY-LERRLTQPHAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFS 223

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Celegans
Match: shw-1 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q8I4L3])

HSP 1 Score: 67.0106 bits (162), Expect = 2.042e-12
Identity = 43/175 (24.57%), Postives = 80/175 (45.71%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCA--------------KLRSQIWDLMENPEKSKSAQLFK 555
            LNVGG +   ++  +LK+  + RL RL   +          ++   + EYFFDRHP  F+ IL+  + G  +    +C     ++ E+WG+D N +  CC+  Y    D +++    ++++ L+      E I  +                +L+ ++W L + P  SK A++  
Sbjct:  105 LNVGG-IRHETYSHVLKKIPATRLSRLTPNLA---------NYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRD-TQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVIS 268

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Celegans
Match: shw-1 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q8I4L3])

HSP 1 Score: 66.6254 bits (161), Expect = 2.766e-12
Identity = 43/173 (24.86%), Postives = 80/173 (46.24%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCA--------------KLRSQIWDLMENPEKSKSAQL 549
            LNVGG +   ++  +LK+  + RL RL   +          ++   + EYFFDRHP  F+ IL+  + G  +    +C     ++ E+WG+D N +  CC+  Y    D +++    ++++ L+      E I  +                +L+ ++W L + P  SK A++
Sbjct:  105 LNVGG-IRHETYSHVLKKIPATRLSRLTPNLA---------NYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRD-TQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARV 266

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Celegans
Match: shw-1 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q8I4L3])

HSP 1 Score: 66.6254 bits (161), Expect = 2.879e-12
Identity = 43/173 (24.86%), Postives = 80/173 (46.24%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCA--------------KLRSQIWDLMENPEKSKSAQL 549
            LNVGG +   ++  +LK+  + RL RL   +          ++   + EYFFDRHP  F+ IL+  + G  +    +C     ++ E+WG+D N +  CC+  Y    D +++    ++++ L+      E I  +                +L+ ++W L + P  SK A++
Sbjct:   32 LNVGG-IRHETYSHVLKKIPATRLSRLTPNLA---------NYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRD-TQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARV 193

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Celegans
Match: shw-1 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q8I4L3])

HSP 1 Score: 66.6254 bits (161), Expect = 2.978e-12
Identity = 43/173 (24.86%), Postives = 80/173 (46.24%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCA--------------KLRSQIWDLMENPEKSKSAQL 549
            LNVGG +   ++  +LK+  + RL RL   +          ++   + EYFFDRHP  F+ IL+  + G  +    +C     ++ E+WG+D N +  CC+  Y    D +++    ++++ L+      E I  +                +L+ ++W L + P  SK A++
Sbjct:   29 LNVGG-IRHETYSHVLKKIPATRLSRLTPNLA---------NYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRD-TQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARV 190

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Celegans
Match: shw-1 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q8I4L3])

HSP 1 Score: 66.6254 bits (161), Expect = 2.997e-12
Identity = 43/173 (24.86%), Postives = 80/173 (46.24%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCA--------------KLRSQIWDLMENPEKSKSAQL 549
            LNVGG +   ++  +LK+  + RL RL   +          ++   + EYFFDRHP  F+ IL+  + G  +    +C     ++ E+WG+D N +  CC+  Y    D +++    ++++ L+      E I  +                +L+ ++W L + P  SK A++
Sbjct:   26 LNVGG-IRHETYSHVLKKIPATRLSRLTPNLA---------NYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRD-TQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARV 187

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Fly
Match: Shab (gene:FBgn0262593 transcript:FBtr0305208)

HSP 1 Score: 117.472 bits (293), Expect = 2.176e-29
Identity = 58/160 (36.25%), Postives = 96/160 (60.00%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            ++NVGG   +V W+  L+R    RL RL    T + I++ CDD+     EYFFDRHPK F+SIL+  + G  +  + MCV++ +DD EYWG+D+  + +CC + Y+ + +   EE  K +   L + + + E   G+CA+ +  +W+L+E P  S +A++
Sbjct:  310 SINVGGVRHEVLWRT-LERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRK-EAESLRQRD-EEEFGEGKCAEYQKYLWELLEKPNTSFAARV 466

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Fly
Match: Shab (gene:FBgn0262593 transcript:FBtr0305201)

HSP 1 Score: 117.472 bits (293), Expect = 2.184e-29
Identity = 58/160 (36.25%), Postives = 96/160 (60.00%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            ++NVGG   +V W+  L+R    RL RL    T + I++ CDD+     EYFFDRHPK F+SIL+  + G  +  + MCV++ +DD EYWG+D+  + +CC + Y+ + +   EE  K +   L + + + E   G+CA+ +  +W+L+E P  S +A++
Sbjct:  310 SINVGGVRHEVLWRT-LERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRK-EAESLRQRD-EEEFGEGKCAEYQKYLWELLEKPNTSFAARV 466

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Fly
Match: Shab (gene:FBgn0262593 transcript:FBtr0305209)

HSP 1 Score: 117.472 bits (293), Expect = 2.197e-29
Identity = 58/160 (36.25%), Postives = 96/160 (60.00%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            ++NVGG   +V W+  L+R    RL RL    T + I++ CDD+     EYFFDRHPK F+SIL+  + G  +  + MCV++ +DD EYWG+D+  + +CC + Y+ + +   EE  K +   L + + + E   G+CA+ +  +W+L+E P  S +A++
Sbjct:  310 SINVGGVRHEVLWRT-LERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRK-EAESLRQRD-EEEFGEGKCAEYQKYLWELLEKPNTSFAARV 466

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Fly
Match: Shab (gene:FBgn0262593 transcript:FBtr0305203)

HSP 1 Score: 117.472 bits (293), Expect = 2.198e-29
Identity = 58/160 (36.25%), Postives = 96/160 (60.00%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            ++NVGG   +V W+  L+R    RL RL    T + I++ CDD+     EYFFDRHPK F+SIL+  + G  +  + MCV++ +DD EYWG+D+  + +CC + Y+ + +   EE  K +   L + + + E   G+CA+ +  +W+L+E P  S +A++
Sbjct:  310 SINVGGVRHEVLWRT-LERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRK-EAESLRQRD-EEEFGEGKCAEYQKYLWELLEKPNTSFAARV 466

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Fly
Match: Shab (gene:FBgn0262593 transcript:FBtr0305202)

HSP 1 Score: 117.472 bits (293), Expect = 2.200e-29
Identity = 58/160 (36.25%), Postives = 96/160 (60.00%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            ++NVGG   +V W+  L+R    RL RL    T + I++ CDD+     EYFFDRHPK F+SIL+  + G  +  + MCV++ +DD EYWG+D+  + +CC + Y+ + +   EE  K +   L + + + E   G+CA+ +  +W+L+E P  S +A++
Sbjct:  310 SINVGGVRHEVLWRT-LERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRK-EAESLRQRD-EEEFGEGKCAEYQKYLWELLEKPNTSFAARV 466

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Zebrafish
Match: kcnb1 (potassium voltage-gated channel, Shab-related subfamily, member 1 [Source:ZFIN;Acc:ZDB-GENE-090831-3])

HSP 1 Score: 108.227 bits (269), Expect = 4.385e-26
Identity = 53/165 (32.12%), Postives = 90/165 (54.55%), Query Frame = 1

Query:   58 FQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            ++   LNVGG   +V W+  L R    RL +L    T + +++ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWG+D+  + +CC   Y+ K +   EE  +      ++   + +N    C++ R ++WDL+E P  S +A++ 
Sbjct:   33 YRRVKLNVGGLPHEVLWRT-LDRLPRTRLGKLRDCKTHESLMEVCDDYNLEDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELKREADTLKDREGEEFDNTC--CSEKRKKLWDLLEKPGSSVAAKIL 194

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Zebrafish
Match: kcnb1 (potassium voltage-gated channel, Shab-related subfamily, member 1 [Source:ZFIN;Acc:ZDB-GENE-090831-3])

HSP 1 Score: 108.227 bits (269), Expect = 4.395e-26
Identity = 53/165 (32.12%), Postives = 90/165 (54.55%), Query Frame = 1

Query:   58 FQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            ++   LNVGG   +V W+  L R    RL +L    T + +++ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWG+D+  + +CC   Y+ K +   EE  +      ++   + +N    C++ R ++WDL+E P  S +A++ 
Sbjct:   29 YRRVKLNVGGLPHEVLWRT-LDRLPRTRLGKLRDCKTHESLMEVCDDYNLEDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELKREADTLKDREGEEFDNTC--CSEKRKKLWDLLEKPGSSVAAKIL 190

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Zebrafish
Match: kcnb1 (potassium voltage-gated channel, Shab-related subfamily, member 1 [Source:ZFIN;Acc:ZDB-GENE-090831-3])

HSP 1 Score: 108.227 bits (269), Expect = 4.402e-26
Identity = 53/165 (32.12%), Postives = 90/165 (54.55%), Query Frame = 1

Query:   58 FQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            ++   LNVGG   +V W+  L R    RL +L    T + +++ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWG+D+  + +CC   Y+ K +   EE  +      ++   + +N    C++ R ++WDL+E P  S +A++ 
Sbjct:   33 YRRVKLNVGGLPHEVLWRT-LDRLPRTRLGKLRDCKTHESLMEVCDDYNLEDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELKREADTLKDREGEEFDNTC--CSEKRKKLWDLLEKPGSSVAAKIL 194

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Zebrafish
Match: kcnb1 (potassium voltage-gated channel, Shab-related subfamily, member 1 [Source:ZFIN;Acc:ZDB-GENE-090831-3])

HSP 1 Score: 108.227 bits (269), Expect = 4.402e-26
Identity = 53/165 (32.12%), Postives = 90/165 (54.55%), Query Frame = 1

Query:   58 FQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            ++   LNVGG   +V W+  L R    RL +L    T + +++ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWG+D+  + +CC   Y+ K +   EE  +      ++   + +N    C++ R ++WDL+E P  S +A++ 
Sbjct:   33 YRRVKLNVGGLPHEVLWRT-LDRLPRTRLGKLRDCKTHESLMEVCDDYNLEDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELKREADTLKDREGEEFDNTC--CSEKRKKLWDLLEKPGSSVAAKIL 194

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Zebrafish
Match: kcnb2 (potassium voltage-gated channel, Shab-related subfamily, member 2 [Source:ZFIN;Acc:ZDB-GENE-070912-170])

HSP 1 Score: 107.071 bits (266), Expect = 1.052e-25
Identity = 54/160 (33.75%), Postives = 85/160 (53.12%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            +NVGG + +V W+  L R    RL +L    T + +++ CDD+  +  EYFFDRHP  F+SIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  +       K   Q +   G C   R ++WDL+E P  S +A++ 
Sbjct:   38 INVGGLVHEVLWRT-LDRLPRTRLGKLRDCNTHETLMEICDDYSLNDNEYFFDRHPGAFSSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETLREKEGDQVDT--GCCPDKRQKLWDLLEKPSSSVAAKVL 194

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Xenopus
Match: KCNB2 (potassium channel, voltage gated Shab related subfamily B, member 2 [Source:NCBI gene;Acc:100489419])

HSP 1 Score: 102.834 bits (255), Expect = 3.815e-24
Identity = 54/160 (33.75%), Postives = 85/160 (53.12%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            +NVGG   +V W+  L R    RL +L    T + +L+ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    C + R ++WDL+E P  S +A++ 
Sbjct:   39 INVGGLNHEVLWRT-LDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETLREREGEEFDNTC--CPEKRKKLWDLLEKPNSSVAAKIL 195

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Xenopus
Match: crisp1.6 (cysteine-rich secretory protein 1 gene 6 [Source:Xenbase;Acc:XB-GENE-5838744])

HSP 1 Score: 85.8853 bits (211), Expect = 1.935e-18
Identity = 52/174 (29.89%), Postives = 88/174 (50.57%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLK------------YDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLFK 555
            N+NVGG   ++S  I L +    RL RL S  + + IL+ CDD+    +E++FDR+P  F  +L+  + G  +  + +C  S + + EYWGI +  + +CC Y Y+ +             D S  E +  +    N+     +N+  +C  LR ++W  MENP  S  +++F 
Sbjct:   20 NINVGGMKKRIS-PITLLQFPDTRLGRLLSCESEESILQICDDYDLVSKEFYFDRNPGLFPYVLYFYETGKLHMMDDLCAFSFSQEIEYWGISEFFLDSCCSYRYHERKLESRRRNWDEDSDASSIETSVDEISDFNQDIMYFDNV--QCGNLRKRLWLTMENPGYSIPSKIFS 190

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Xenopus
Match: KCNS2 (potassium voltage-gated channel, modifier subfamily S, member 2 [Source:NCBI gene;Acc:101732753])

HSP 1 Score: 83.1889 bits (204), Expect = 1.552e-17
Identity = 51/193 (26.42%), Postives = 96/193 (49.74%), Query Frame = 1

Query:   25 LNGLLNSFYMHFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIY--------------NLKYDISKEEYNKVQTIYLN--KLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLFK 555
            L GL ++ +   +I+ +NVGG   ++ +  +L R    RLC+L +  + + IL+ CDD+     E++FDR+P+ F  +LH    G  +    +CV S   + EYWGI++  + +CC Y Y              N + + +   ++++   Y +  K + QP         +R ++W  ++NP  S  +++F 
Sbjct:    6 LMGLPDTGFEDTEIS-INVGGYKKRLRYDTLL-RFPETRLCKLLACRSKESILELCDDYDDTKNEFYFDRNPELFPYVLHFYNTGKLHVMGELCVFSFCQEIEYWGINEFFIDSCCSYSYHGRKVEPEQDQWEENSERESTTSSFDEILAFYHDAAKFDRQP------LGNIRRRLWLALDNPGYSILSRIFS 190

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Xenopus
Match: sv2b (synaptic vesicle glycoprotein 2B [Source:Xenbase;Acc:XB-GENE-6041859])

HSP 1 Score: 82.0333 bits (201), Expect = 4.519e-17
Identity = 55/175 (31.43%), Postives = 88/175 (50.29%), Query Frame = 1

Query:   61 QIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEE--YNKVQTIYLNKLNYQPENIHGR---------CAKLRSQIWDLMENPEKSKSAQLF 552
            ++  LNVGG    V  K +L+  ++ RL +L +  + + IL+ CDD+    +EY+FDR+P  F  IL+    G  +    +CV S + + EYWGI++  + +CC   Y  K +I  E+    K   I L   +    ++  R            +R +IW  +ENP  S SA+LF
Sbjct:   15 ELVKLNVGGFKQSVDQKTLLRFPHT-RLGKLLNCRSEEAILELCDDYNVADKEYYFDRNPSLFRYILNFYYTGKLHVMEELCVFSFSQEIEYWGINELFIDSCCSNKYQEKKEIIAEKDWDQKSDIISLGSSSSDQSSVFERELEMFDTLKFGDIRRKIWIRLENPAYSLSAKLF 188

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Xenopus
Match: ENSXETT00000039283.1 (potassium voltage-gated channel subfamily V member 2-like [Source:NCBI gene;Acc:100494007])

HSP 1 Score: 81.6481 bits (200), Expect = 5.765e-17
Identity = 50/174 (28.74%), Postives = 85/174 (48.85%), Query Frame = 1

Query:   37 LNSFYMHFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIH--GR-CAKLRSQIWDLMENPEKSKSAQL 549
            +N FY+     NLNVGG+ F++ +++   R  S R+ +L +     + L  CDDF   + EYFFDR P  F  I H  + G+ +  + +C  +  ++ EYWG+       CC  ++    D    EY K +     ++       H  G+     + ++W+L+ENP  S  A++
Sbjct:   62 INLFYL-----NLNVGGKKFQIDYRV-AARYPSTRIGKLAACSDLVKRLDLCDDFSVQMNEYFFDRDPVVFYYIFHFYRCGILWIMDELCPHNFLEEIEYWGLHLKYTQRCCHILFEEHQD-EIMEYIKTERDLQAEVERHDHEKHFEGKWLGDFKIKMWNLVENPYSSVQAKI 228

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Mouse
Match: Kcnb1 (potassium voltage gated channel, Shab-related subfamily, member 1 [Source:MGI Symbol;Acc:MGI:96666])

HSP 1 Score: 110.538 bits (275), Expect = 8.560e-27
Identity = 56/160 (35.00%), Postives = 86/160 (53.75%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLQVCDDYSLEDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

[Close]

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLQVCDDYSLEDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Mouse
Match: Kcnb2 (potassium voltage gated channel, Shab-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:99632])

HSP 1 Score: 105.916 bits (263), Expect = 2.772e-25
Identity = 54/160 (33.75%), Postives = 85/160 (53.12%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            +NVGG   +V W+  L R    RL +L    T + +L+ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    C + R ++WDL+E P  S +A++ 
Sbjct:   39 INVGGLNHEVLWRT-LDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTC--CPEKRKKLWDLLEKPNSSVAAKIL 195

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Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            +NVGG   +V W+  L R    RL +L    T + +L+ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    C + R ++WDL+E P  S +A++ 
Sbjct:   39 INVGGLNHEVLWRT-LDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTC--CPEKRKKLWDLLEKPNSSVAAKIL 195

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Mouse
Match: Kcns1 (K+ voltage-gated channel, subfamily S, 1 [Source:MGI Symbol;Acc:MGI:1197019])

HSP 1 Score: 100.138 bits (248), Expect = 1.802e-23
Identity = 52/173 (30.06%), Postives = 88/173 (50.87%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIH-----------GRCAKLRSQIWDLMENPEKSKSAQLFK 555
             +NVGG    +S +  L R    RL RL +A + +Q  + CDD+ A   E++FDRHP FF  +LH  + G  +  + +CV +   + +YWG+ +N ++ CC   Y L+  +++       +   + ++  P+ I             RC +LR ++W  MENP  S  ++LF 
Sbjct:   22 RVNVGGVRRLLSARA-LARFPGTRLGRLQAAASEEQARRLCDDYDAAAHEFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALATCCRARY-LERRVARPRAWDEDSDAPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFS 192

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BLAST of Potassium voltage-gated channel protein Shab vs. UniProt/SwissProt
Match: sp|Q9MZ19|KCNB1_RABIT (Potassium voltage-gated channel subfamily B member 1 OS=Oryctolagus cuniculus OX=9986 GN=KCNB1 PE=2 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 1.705e-26
Identity = 57/160 (35.62%), Postives = 86/160 (53.75%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

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BLAST of Potassium voltage-gated channel protein Shab vs. UniProt/SwissProt
Match: sp|O18868|KCNB1_PIG (Potassium voltage-gated channel subfamily B member 1 OS=Sus scrofa OX=9823 GN=KCNB1 PE=2 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 1.705e-26
Identity = 57/160 (35.62%), Postives = 86/160 (53.75%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. UniProt/SwissProt
Match: sp|Q14721|KCNB1_HUMAN (Potassium voltage-gated channel subfamily B member 1 OS=Homo sapiens OX=9606 GN=KCNB1 PE=1 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 1.705e-26
Identity = 57/160 (35.62%), Postives = 86/160 (53.75%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

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BLAST of Potassium voltage-gated channel protein Shab vs. UniProt/SwissProt
Match: sp|P17970|KCNAB_DROME (Potassium voltage-gated channel protein Shab OS=Drosophila melanogaster OX=7227 GN=Shab PE=1 SV=2)

HSP 1 Score: 111.694 bits (278), Expect = 2.142e-26
Identity = 56/160 (35.00%), Postives = 95/160 (59.38%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            ++NVGG   +V W+  L+R    RL RL    T + I++ CDD+     EYFFDRHPK F+SIL+  + G  +  + MCV++ +DD EYWG+D+  + +CC + Y+ + +   EE  K +   L + + + E   G+ ++ +  +W+L+E P  S +A++
Sbjct:  280 SINVGGVRHEVLWRT-LERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRK-EAESLRQRD-EEEFGEGKFSEYQKYLWELLEKPNTSFAARV 436

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BLAST of Potassium voltage-gated channel protein Shab vs. UniProt/SwissProt
Match: sp|P15387|KCNB1_RAT (Potassium voltage-gated channel subfamily B member 1 OS=Rattus norvegicus OX=10116 GN=Kcnb1 PE=1 SV=3)

HSP 1 Score: 110.538 bits (275), Expect = 5.987e-26
Identity = 56/160 (35.00%), Postives = 86/160 (53.75%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG   +V W+  L R    RL +L    T   +L+ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWGID+  + +CC   Y+ K +   EE  +       +   + +N    CA+ R ++WDL+E P  S +A++ 
Sbjct:   35 LNVGGLAHEVLWRT-LDRLPRTRLGKLRDCNTHDSLLQVCDDYSLEDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTC--CAEKRKKLWDLLEKPNSSVAAKIL 191

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BLAST of Potassium voltage-gated channel protein Shab vs. TrEMBL
Match: A0A448WR55 (BTB domain-containing protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS11553 PE=4 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 1.507e-32
Identity = 64/161 (39.75%), Postives = 98/161 (60.87%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGR--CAKLRSQIWDLMENPEKSKSAQL 549
            LNVGG+  +V W   L+R  + RL RL SA++ +QI++ CDD+     EYFFDRHP+ F  IL++ + G  +  + MCV++  +D +YWG+++ LM  CC + Y  K +  +EE  K+    L++     E   GR  CA  R ++WDLME P+ S SA++
Sbjct:   27 LNVGGECHEVLWHT-LERLPTSRLGRLRSAVSHEQIIRLCDDYSLAGNEYFFDRHPRSFACILNMYRTGRLHMVDEMCVLAFHEDVKYWGLNEALMETCCQHRYFQKKEQVEEEMRKIGEACLDRTK---EEEFGRDSCAPYRKRLWDLMEKPQTSMSARV 183

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BLAST of Potassium voltage-gated channel protein Shab vs. TrEMBL
Match: K1Q9M4 (Potassium voltage-gated channel protein Shab OS=Crassostrea gigas OX=29159 GN=CGI_10015571 PE=4 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 5.945e-29
Identity = 62/158 (39.24%), Postives = 94/158 (59.49%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQ 546
            LNVGG   +V W+  L R    RL +L S  T + +++ CDD+  D  EYFFDRHP+ F+SIL+  + G  +    MCV+S +DD EYWG+D+  + +CC + Y+ K +   EE  K +   L +     +  +G CAK R ++WDL+E P+ S +A+
Sbjct:  128 LNVGGVKHEVMWRT-LDRMPHTRLGKLQSCNTHESLMEICDDYTLDCNEYFFDRHPRSFSSILNFYRTGKLHLVEEMCVLSFSDDLEYWGVDELYLESCCQHKYHQKKEHVYEEIRK-EAESLRQRESDEDFGNGMCAKWRKKVWDLLEKPQSSMAAR 283

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BLAST of Potassium voltage-gated channel protein Shab vs. TrEMBL
Match: A0A1S3J453 (potassium voltage-gated channel subfamily B member 1 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106169919 PE=3 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 1.437e-28
Identity = 60/166 (36.14%), Postives = 97/166 (58.43%), Query Frame = 1

Query:   55 HFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            H     +NVGG   +V WK + +  +S RL +L ++ + + I+  CDD+     EYFFDRHP+ F SI++  + G  +    MCV+S +DD EYWG+D+  + +CC + Y+ K +   EE  K +   L +   +     GRCAK R ++WDL+E P+ S++A++ 
Sbjct:  135 HSNRVTINVGGVKHEVMWKTLDRMPHS-RLGKLKTSTSHESIMDLCDDYSLMDNEYFFDRHPRSFASIINFYRTGKLHLVEEMCVLSFSDDLEYWGVDELYLESCCQHRYHQKKEHVYEEMRK-EAESLREGGEEENFGTGRCAKWRQKLWDLLEKPQTSRAARVL 298

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BLAST of Potassium voltage-gated channel protein Shab vs. TrEMBL
Match: A0A0R3T0E4 (BTB domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS280 PE=4 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 1.449e-28
Identity = 59/161 (36.65%), Postives = 96/161 (59.63%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHG--RCAKLRSQIWDLMENPEKSKSAQL 549
            LNVGG   +V W+ + K  +S RL RL  A+T Q+I++ CDD+  +  EYFFDRHP+ F  +L++ + G  +    +CV++   D  YWGI+ + M  CC   Y  K +  +EE  KV  I++ +++   E   G  +CA  R ++WD++E P+ S +A++
Sbjct:  128 LNVGGDRHEVMWRTLEKIPHS-RLGRLQHAVTHQEIMQLCDDYNIEANEYFFDRHPQTFGCVLNMYRTGHLHTLEDICVLAYHSDLIYWGIEDHNMDPCCLSRYYQKKEHVEEEMKKVNEIFMQQMD---EEYFGEDKCAIYRKKLWDILEKPQTSTAARV 284

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BLAST of Potassium voltage-gated channel protein Shab vs. TrEMBL
Match: A0A3P7LGD2 (BTB domain-containing protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS6758 PE=4 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 2.132e-28
Identity = 56/159 (35.22%), Postives = 93/159 (58.49%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            LNVGG   +V W+ + +  +S RL RL  A+T + I + CDD+  +  EYFFDRHP+ F  +L++ + G  +    +C+++   D  YWGID+  M  CC   Y  K +  ++E  KV  I+L +++ +      RCA  R ++WD++E P+ S +A++
Sbjct:   12 LNVGGDRHEVLWRTLNRLPHS-RLGRLGHAVTHEAISQICDDYSLEDNEYFFDRHPQSFGCVLNMYRTGHLHTVEDICILAYHSDLVYWGIDERHMDPCCLSRYYQKKEHVEDEMRKVNEIFLQQMDTEYSG-DDRCAVYRKKLWDILEKPQTSMAARV 168

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Cavefish
Match: KCNB1 (potassium voltage-gated channel subfamily B member 1-like [Source:NCBI gene;Acc:103041067])

HSP 1 Score: 111.309 bits (277), Expect = 2.711e-27
Identity = 56/160 (35.00%), Postives = 87/160 (54.37%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG L +V W+  L R    RL +L    T + I++ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + ++WGID+  + +CC   Y+ K +   EE  +       +   + +N    C + R ++WDL+E P  S +A++ 
Sbjct:   31 LNVGGLLHEVLWRT-LDRLPRTRLGKLRDCNTHESIMEVCDDYNLDDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDFWGIDEIYLESCCQARYHQKKEQMNEELKREAETMREREGEEFDNTC--CTEKRMKLWDLLEKPSSSFAAKIL 187

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Cavefish
Match: kcnb1 (potassium voltage-gated channel subfamily B member 1 [Source:NCBI gene;Acc:103042196])

HSP 1 Score: 108.997 bits (271), Expect = 2.252e-26
Identity = 54/165 (32.73%), Postives = 89/165 (53.94%), Query Frame = 1

Query:   58 FQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            ++   LNVGG   +V W+  L R    RL +L    T + ++  CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWG+D+  + +CC   Y+ K +   EE  +      ++   + +N    C++ R ++WDL+E P  S +A++ 
Sbjct:   33 YRRVRLNVGGLPHEVLWRT-LDRLPRTRLGKLRDCRTHEALMDVCDDYNLDDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELKREADTLKDREGEEFDNTC--CSEKRKKLWDLLEKPGSSVAAKIL 194

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Cavefish
Match: si:dkey-192j17.1 (potassium voltage-gated channel subfamily B member 2 [Source:NCBI gene;Acc:103036535])

HSP 1 Score: 105.916 bits (263), Expect = 2.138e-25
Identity = 54/158 (34.18%), Postives = 88/158 (55.70%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQ 546
            +NVGG   +V W+  L R    RL +L    T + +++ CDD+  +  EYFFDRHP  FTSIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  + +   L + + + E  +  C++ R ++WDL+E P  S +A+
Sbjct:   39 INVGGLNHEVLWRT-LDRLPRTRLGKLRDCNTHESLMEVCDDYSLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRR-EAETLRERDGEGEFDNTCCSEKRKKLWDLLEKPNSSVAAK 194

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Cavefish
Match: kcnb2 (potassium voltage-gated channel subfamily B member 2-like [Source:NCBI gene;Acc:103023195])

HSP 1 Score: 105.145 bits (261), Expect = 4.081e-25
Identity = 53/160 (33.12%), Postives = 84/160 (52.50%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            +NVGG + +V W+  L R    RL +L    T   +++ CDD+  +  EYFFDRHP  F+SIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  +       K   + +   G C   R ++WDL+E P  S +A++ 
Sbjct:   38 INVGGLVHEVLWRT-LDRLPRTRLGKLRDCNTHDTLMEICDDYSLNDNEYFFDRHPGAFSSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETLREKEGEEVDT--GCCPDKRQKLWDLLEKPSSSVAAKVL 194

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Cavefish
Match: si:dkey-43k4.5 (si:dkey-43k4.5 [Source:ZFIN;Acc:ZDB-GENE-120215-82])

HSP 1 Score: 97.4413 bits (241), Expect = 1.163e-22
Identity = 59/180 (32.78%), Postives = 97/180 (53.89%), Query Frame = 1

Query:   46 FYMHFQIANLNVGGQLFKVSW-KIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLK----YDISKEEYNKVQTI-----YLNKLNYQPENIHG-RCAKLRSQIWDLMENPEKSKSAQLF 552
            F M  ++ N+NVGG   K S+   +L++    RLCRL S  T + IL+ CDD+    +E++FDR+P  F  +LH  + G  +    +CV S   + EYWGI++  + NCC Y Y+ +    +  S +E + V ++      ++ LN   ++    RC  +R  +W  +ENP  S  ++LF
Sbjct:   17 FCMKDRLLNINVGG--LKHSFCSSLLQKFPDTRLCRLLSCDTEEAILQICDDYDVQKKEFYFDRNPGLFPYVLHFYQTGKLHIMEELCVFSFCQEIEYWGINEFFLDNCCSYRYHDRKLESHHKSWDEESDVSSVDTSVDEISDLNKDIQHFQDMRCGNVRKCLWLTLENPGYSIPSKLF 194

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004244.1 (pep scaffold:Pmarinus_7.0:GL488450:6918:7731:1 gene:ENSPMAG00000003882.1 transcript:ENSPMAT00000004244.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 101.679 bits (252), Expect = 7.625e-27
Identity = 52/161 (32.30%), Postives = 88/161 (54.66%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAI--TSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            +NVGG   +  W+  L+R    RL RL + +  + + I++ CDD+     E+FFDRHP  FTSIL+  + G  +    MC +S + + +YWG+D+  + +CC   Y+ K +   EE  +       +   Q +  +  CA+ R ++WDL+E P  S +A++
Sbjct:    1 INVGGITHEALWRT-LERLPRTRLGRLQACVVGSEEAIMELCDDYSRADNEFFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELRREAESAREREGEQFDATY--CAEKRKKLWDLLEKPNSSLAAKV 158

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008567.1 (pep scaffold:Pmarinus_7.0:GL478165:47990:49229:1 gene:ENSPMAG00000007760.1 transcript:ENSPMAT00000008567.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 100.523 bits (249), Expect = 2.887e-26
Identity = 54/160 (33.75%), Postives = 81/160 (50.62%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGR-CAKLRSQIWDLMENPEKSKSAQL 549
            LNVGG   +V W+  L+R    RL +L  +    +    CDD      EYFFDRHP  FTSIL+  + G  +    MC +S + + +YWG+D+  + +CC   Y+ K +   EE  +             E   G  CA+ R ++WDL+E P  S +A++
Sbjct:    9 LNVGGVCHEVLWRT-LERLPRTRLGKLRDSSAEGEAASLCDDHSPGENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELRREAD---TAREMDAEVFDGACCAEKRKKLWDLLEKPNSSVAAKV 164

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004235.1 (pep scaffold:Pmarinus_7.0:GL476413:398954:411573:-1 gene:ENSPMAG00000003870.1 transcript:ENSPMAT00000004235.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.449 bits (254), Expect = 2.898e-25
Identity = 53/161 (32.92%), Postives = 85/161 (52.80%), Query Frame = 1

Query:   67 ANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGR-CAKLRSQIWDLMENPEKSKSAQ 546
              LNVGG + +V W+  L+R    RL RL++  T   + + CDD+     EYFFDRHP  F S+L+  + G  + +  MC +S   + +YWG+D+  +  CC   Y+ K +   EE  +      +    + +   G  CA  R ++W+L+ENP  S +A+
Sbjct:    2 VRLNVGGLVHEVLWRT-LERLPRTRLGRLHATNTHGALSELCDDYSIADNEYFFDRHPGAFASVLNFYRTGRLHMSEEMCALSFGQELDYWGVDEIYLETCCQARYHQKKEQMSEELRREAE---SAREREGDEFEGTCCADKRRKLWELLENPNSSLAAK 158

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001527.1 (pep scaffold:Pmarinus_7.0:GL482102:431:1368:-1 gene:ENSPMAG00000001382.1 transcript:ENSPMAT00000001527.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.1738 bits (178), Expect = 1.913e-16
Identity = 32/108 (29.63%), Postives = 61/108 (56.48%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSA-ITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLK 393
            LN+GG  F+++ + +L R    RL RL    ++S + +  CDD+ A   EYFFDR P+ F  +    + GV + ++ +C ++  ++ +YWG+     ++CC  ++  +
Sbjct:    1 LNIGGTKFRIA-RCVLARHPKTRLGRLAKPELSSSERIDVCDDYAAATREYFFDRDPEVFRLVFTYYRTGVLWVSDELCPINYVEEIQYWGLQVRHTNHCCRIVFEER 107

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Sea Lamprey
Match: kcnf1b (potassium voltage-gated channel, subfamily F, member 1b [Source:ZFIN;Acc:ZDB-GENE-090312-39])

HSP 1 Score: 75.485 bits (184), Expect = 6.533e-16
Identity = 45/158 (28.48%), Postives = 74/158 (46.84%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQ 546
            +NVGG    +  +++ +   S+ L  L     + +   Y DDF  D  E+FFDR P+ F  IL    FG  +   + C M    + ++WG+  + + +CC + Y+   +   E    V+T  L           GRC + R  +W LME P+ S+ A+
Sbjct:    4 VNVGGSRHVLRSELLARLPDSL-LATLLVRPGAARRPAY-DDFDPDSGEFFFDRDPRAFDRILDAYHFGEVHMDRSACPMCFKQEMDFWGVGADCLDDCCRFRYSELQEELDEIVQMVET-ELRDSGTAGAAQRGRCERARVGVWQLMEKPDSSRLAR 158

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BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Nematostella
Match: EDO46844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP34])

HSP 1 Score: 70.0922 bits (170), Expect = 9.664e-15
Identity = 47/175 (26.86%), Postives = 81/175 (46.29%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKI-ILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLN---------------YQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            LNVGG  FK    I  L+     RLC L       Q +    ++ A+  EYFFDRHP  F  IL+  + G  +  N +C     ++ +YWGID+  +  CC+ +Y       +E+  K++   L   +               ++ E++    ++++ +IW  +E P  S+ A++
Sbjct:   10 LNVGG--FKHETYISTLRNIPDSRLCNLGE---RHQSMNKASEYDANKNEYFFDRHPGVFAHILNYYRTGKLHCPNDVCGPVFEEELQYWGIDEEQVETCCWELYKQH----REKQEKLKCFKLPGFDDTEESPLLTSQDSGLFEAEDVISWWSRVQPKIWKSLEEPHSSQLAKV 175

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Nematostella
Match: EDO45172 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTZ3])

HSP 1 Score: 69.707 bits (169), Expect = 1.385e-13
Identity = 51/177 (28.81%), Postives = 80/177 (45.20%), Query Frame = 1

Query:   70 NLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIY--------NLK--------YDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
             LNVGGQ  +     I  R Y     RLY  +  + + K   D+ ++  E FFDRHPK F  +L+  + G  +  N +C     ++  YWGID+  M  CC+  Y        NLK         DI  +   + +T        + + +H    K + +IW ++E P  S++A+ F
Sbjct:   13 TLNVGGQKHETYLSTI--RNYPD--TRLYWVV--ENVTK-AIDYHSEKIELFFDRHPKIFDQVLNYYRTGKLHCPNDVCGPLFEEELAYWGIDEKEMEPCCWTTYTQHREAEHNLKSFNVTDFSTDIDSDRQEETET------TSKAKGLHPFWVKYQPRIWAILEEPRSSRTAKAF 176

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Nematostella
Match: EDO47871 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL57])

HSP 1 Score: 64.3142 bits (155), Expect = 8.231e-12
Identity = 46/177 (25.99%), Postives = 84/177 (47.46%), Query Frame = 1

Query:   67 ANLNVGGQLFKVSWKIILKRAYSVRLCRLY----SAITSQQILKYCDDFQAD--IEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPEN----------IHGRCAKLRSQIWDLMENPEKSKSAQL 549
            A LN+ G  F++ W  I +  ++ RL ++Y         Q++   CD  +      E FF R P+ F +I+   + G F+   T+C+     + +YWGI    M +CC+  ++ + + + E   K++  +   LN + E              + A+L+ ++WDL ENP  S  A++
Sbjct:   15 AQLNISGVRFELLWSSIKEFPFT-RLGKVYFWYEHGDNWQEL---CDGVKMGEKTAEVFFQRDPEIFKTIMCYYRNGKFHFPRTICIEHFQRELKYWGISIKNMGDCCYNHFHQENE-AVENLMKIKEAFKKDLNMKKEQDEVDLLLEVESRSKLARLKRKMWDLFENPHSSFMAKI 186

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Nematostella
Match: EDO38237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDJ4])

HSP 1 Score: 63.5438 bits (153), Expect = 1.517e-11
Identity = 35/123 (28.46%), Postives = 58/123 (47.15%), Query Frame = 1

Query:  217 EYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQP-ENIHGRCA---------KLRSQIWDLMENPEKSKSAQLFK 555
            EYFFDRHP  F  +L+  + G  +    MC     ++  +WGID+  M  CC+  Y  ++  ++E          N L  +P EN  G            +++ Q+W+ ++ P  SK A++F 
Sbjct:   58 EYFFDRHPTAFCQVLNFYRTGKLHCPTEMCGPMFEEELIFWGIDEKQMEPCCWGTYT-QHREAEENLKAFVGPGFNDLKDEPAENHMGSYGSINELNCWKRIQPQLWETLDEPHSSKMAKIFS 179

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Nematostella
Match: EDO25793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DVG6])

HSP 1 Score: 60.8474 bits (146), Expect = 1.532e-11
Identity = 34/121 (28.10%), Postives = 57/121 (47.11%), Query Frame = 1

Query:  217 EYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQP-ENIHGRCA---------KLRSQIWDLMENPEKSKSAQL 549
            EYFFDRHP  F  +L+  + G  +    MC     ++  +WGID+  M  CC+  Y  ++  ++E          N L  +P EN  G            +++ Q+W+ ++ P  SK A++
Sbjct:   39 EYFFDRHPTAFCQVLNFYRTGKLHCPTEMCGPMFEEELIFWGIDEKQMEPCCWGTYT-QHREAEENLKAFVGPGFNDLKDEPAENHMGSYGSINELNCWKRIQPQLWETLDEPHSSKMAKV 158

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Medaka
Match: kcnb1 (potassium voltage-gated channel subfamily B member 1 [Source:NCBI gene;Acc:101167947])

HSP 1 Score: 110.538 bits (275), Expect = 1.769e-27
Identity = 61/171 (35.67%), Postives = 93/171 (54.39%), Query Frame = 1

Query:   64 IANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGR---------CAKLRSQIWDLMENPEKSKSAQL 549
            IA LNVGG L +V W+  L+R    RL +L    T   I++ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + ++WGID+  + +CC      +Y   KE+ N+       +L  + EN+  R         C++ R ++WDL+E P  S +A++
Sbjct:   17 IAVLNVGGLLHEVLWRT-LERLPRTRLGKLRDCNTHDSIMEICDDYSLDGNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDFWGIDEIYLESCC----QARYHQKKEQMNE-------ELKREAENMREREGEEFTTTCCSEKRKKLWDLLEKPSSSFAAKV 175

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Medaka
Match: kcnb1 (potassium voltage-gated channel subfamily B member 1 [Source:NCBI gene;Acc:101167947])

HSP 1 Score: 110.923 bits (276), Expect = 4.244e-27
Identity = 61/175 (34.86%), Postives = 94/175 (53.71%), Query Frame = 1

Query:   55 HFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGR---------CAKLRSQIWDLMENPEKSKSAQLF 552
            H +   LNVGG L +V W+  L+R    RL +L    T   I++ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + ++WGID+  + +CC   Y+ K    KE+ N+       +L  + EN+  R         C++ R ++WDL+E P  S +A++ 
Sbjct:   26 HSRRVRLNVGGLLHEVLWRT-LERLPRTRLGKLRDCNTHDSIMEICDDYSLDGNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDFWGIDEIYLESCCQARYHQK----KEQMNE-------ELKREAENMREREGEEFTTTCCSEKRKKLWDLLEKPSSSFAAKIL 188

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Medaka
Match: kcnb1 (potassium voltage-gated channel subfamily B member 1 [Source:NCBI gene;Acc:101167947])

HSP 1 Score: 109.383 bits (272), Expect = 7.168e-27
Identity = 60/175 (34.29%), Postives = 93/175 (53.14%), Query Frame = 1

Query:   55 HFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGR---------CAKLRSQIWDLMENPEKSKSAQLF 552
            H +   LNVGG L +V W+  L+R    RL +L    T   I++ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + ++WGID+  + +CC      +Y   KE+ N+       +L  + EN+  R         C++ R ++WDL+E P  S +A++ 
Sbjct:   26 HSRRVRLNVGGLLHEVLWRT-LERLPRTRLGKLRDCNTHDSIMEICDDYSLDGNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDFWGIDEIYLESCC----QARYHQKKEQMNE-------ELKREAENMREREGEEFTTTCCSEKRKKLWDLLEKPSSSFAAKIL 188

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Medaka
Match: kcnb1 (potassium voltage-gated channel subfamily B member 1 [Source:NCBI gene;Acc:101167947])

HSP 1 Score: 108.997 bits (271), Expect = 9.393e-27
Identity = 59/172 (34.30%), Postives = 92/172 (53.49%), Query Frame = 1

Query:   64 IANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGR---------CAKLRSQIWDLMENPEKSKSAQLF 552
            +  LNVGG L +V W+  L+R    RL +L    T   I++ CDD+  D  EYFFDRHP  FTSIL+  + G  +    MC +S + + ++WGID+  + +CC      +Y   KE+ N+       +L  + EN+  R         C++ R ++WDL+E P  S +A++ 
Sbjct:    4 LVRLNVGGLLHEVLWRT-LERLPRTRLGKLRDCNTHDSIMEICDDYSLDGNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDFWGIDEIYLESCC----QARYHQKKEQMNE-------ELKREAENMREREGEEFTTTCCSEKRKKLWDLLEKPSSSFAAKIL 163

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Medaka
Match: ENSORLT00000035166.1 (potassium voltage-gated channel subfamily B member 2-like [Source:NCBI gene;Acc:101155143])

HSP 1 Score: 108.612 bits (270), Expect = 2.676e-26
Identity = 56/160 (35.00%), Postives = 84/160 (52.50%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGG + +V W+  L R    RL RL    T + +L+ CDD+     EYFFDRHP  F+SIL+  + G  +    MC +S   + +YWGID+  + +CC   Y+ K +   EE  +      +K     +   G C   R ++WDL+E P  S +A++ 
Sbjct:   41 LNVGGLIHEVLWRT-LDRLPRTRLGRLRDCNTHESLLEICDDYSLPENEYFFDRHPMAFSSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETLRDKEGEVED--QGCCPDKRQKLWDLLEKPSSSVAAKIL 197

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Planmine SMEST
Match: SMESG000038809.1 (SMESG000038809.1)

HSP 1 Score: 347.051 bits (889), Expect = 1.191e-122
Identity = 165/166 (99.40%), Postives = 166/166 (100.00%), Query Frame = 1

Query:   52 MHFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            MHFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQ+
Sbjct:    1 MHFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQV 166

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Planmine SMEST
Match: SMESG000054120.1 (SMESG000054120.1)

HSP 1 Score: 124.405 bits (311), Expect = 6.009e-32
Identity = 64/160 (40.00%), Postives = 98/160 (61.25%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIH-GRCAKLRSQIWDLMENPEKSKSAQL 549
            LNVGG+  +V WK  LKR    RL  L  A+T  QIL+ CDD+     EY+FDRHPK F  +L + + G  +    +C+++  DD +YWGI++NLM +CC + Y++K +   +E  KV+ I  N  + Q ++    R  + R ++WDLM+NP+ S +AQ+
Sbjct:   74 LNVGGECHEVMWKT-LKRMPFTRLGLLRKALTHDQILEICDDYDLTKNEYYFDRHPKSFLCVLTMFRTGNLHMLEDLCIVNFADDLDYWGINENLMESCCHHRYHMKRERVNDEIKKVKDI--NDESNQIDSFGTSRFHQFRRRLWDLMDNPQTSIAAQI 230

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Planmine SMEST
Match: SMESG000004060.1 (SMESG000004060.1)

HSP 1 Score: 122.479 bits (306), Expect = 1.668e-31
Identity = 58/160 (36.25%), Postives = 95/160 (59.38%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQLF 552
            LNVGGQ+ ++ W   LKR    RL +L  A    +ILK CDD+  +  EYFFDRHPK F  ++ + + G  +    MCVMS ++D EYWGI+++LM +CC + Y+++ +  +EE  K+  I  +    + E  +    +++++IW+  E P+ S  A++ 
Sbjct:   50 LNVGGQIHEIMWTT-LKRMPHTRLGKLLQASAHCEILKICDDYDLEKNEYFFDRHPKSFDCVITMFRSGSLHMQEDMCVMSFSEDLEYWGINESLMEHCCQHNYHMRKEQMQEELKKINLICCDAKKCEDEIENSTSMRIKNKIWNTFEKPQTSTMARVL 208

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Planmine SMEST
Match: SMESG000048635.1 (SMESG000048635.1)

HSP 1 Score: 112.079 bits (279), Expect = 3.966e-30
Identity = 57/154 (37.01%), Postives = 94/154 (61.04%), Query Frame = 1

Query:   73 LNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKS 534
            +NVGG++F + W  + +R ++ RL +L  A+T ++IL+ CD++ A   E FFDRHPK F +I +LL+ G FY     C   + ++ +YWGI  N +S CC Y ++ + ++  EE  KV+ I + +L         +  K RS++W++ME+PE S
Sbjct:   13 INVGGKIFLLQWSAV-QRFHNSRLEQLCRAVTLEEILRLCDEYDAKTGECFFDRHPKSFENIWNLLQNGRFYFDTEFCASYVLEELKYWGISINYLSYCCRYNFDRRKELIDEENEKVRNI-MYRLKITKSKSKAKFGKCRSKLWNIMEHPETS 164

[Close]

BLAST of Potassium voltage-gated channel protein Shab vs. Planmine SMEST
Match: SMESG000029097.1 (SMESG000029097.1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.015e-20
Identity = 53/164 (32.32%), Postives = 87/164 (53.05%), Query Frame = 1

Query:   58 FQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDFQADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDKNLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQIWDLMENPEKSKSAQL 549
            F+   LNVGGQ+ +V W   L    + RL ++  + T   +++ CDD+     EYFFDR+P  F  IL+  +    + +  MCV+S ++D  YWGI    ++ CC   Y  + +  +EE  K +    N+ + +   I G+ A +R  IW++ + P  SK AQ+
Sbjct:  354 FKRVILNVGGQIHEVLWNT-LDYLPNTRLGKIRRSETHLDLMQICDDYDLSKNEYFFDRNPTSFPCILNFYRTRTLHVSENMCVLSFSEDLIYWGIKDVFLNACCQQKYYHRKENVEEEMRKEEDALKNEDDIEYFGI-GKLADIRELIWNVFDKPNTSKLAQV 515

The following BLAST results are available for this feature:

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Human
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Celegans
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Fly
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Zebrafish
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Xenopus
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Mouse
BLAST of Potassium voltage-gated channel protein Shab vs. UniProt/SwissProt
BLAST of Potassium voltage-gated channel protein Shab vs. TrEMBL
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Cavefish
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Sea Lamprey
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Yeast
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Nematostella
BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Medaka
BLAST of Potassium voltage-gated channel protein Shab vs. Planmine SMEST

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNB1	3.550e-27	35.63	potassium voltage-gated channel subfamily B member...	[more]
KCNB1	3.550e-27	35.63	potassium voltage-gated channel subfamily B member...	[more]
KCNB2	6.627e-25	33.75	potassium voltage-gated channel subfamily B member...	[more]
KCNS1	7.462e-23	30.06	potassium voltage-gated channel modifier subfamily...	[more]
KCNS1	7.462e-23	30.06	potassium voltage-gated channel modifier subfamily...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
shw-1	2.042e-12	24.57	SHaW family of potassium channels [Source:UniProt...	[more]
shw-1	2.766e-12	24.86	SHaW family of potassium channels [Source:UniProt...	[more]
shw-1	2.879e-12	24.86	SHaW family of potassium channels [Source:UniProt...	[more]
shw-1	2.978e-12	24.86	SHaW family of potassium channels [Source:UniProt...	[more]
shw-1	2.997e-12	24.86	SHaW family of potassium channels [Source:UniProt...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Shab	2.176e-29	36.25	gene:FBgn0262593 transcript:FBtr0305208	[more]
Shab	2.184e-29	36.25	gene:FBgn0262593 transcript:FBtr0305201	[more]
Shab	2.197e-29	36.25	gene:FBgn0262593 transcript:FBtr0305209	[more]
Shab	2.198e-29	36.25	gene:FBgn0262593 transcript:FBtr0305203	[more]
Shab	2.200e-29	36.25	gene:FBgn0262593 transcript:FBtr0305202	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnb1	4.385e-26	32.12	potassium voltage-gated channel, Shab-related subf...	[more]
kcnb1	4.395e-26	32.12	potassium voltage-gated channel, Shab-related subf...	[more]
kcnb1	4.402e-26	32.12	potassium voltage-gated channel, Shab-related subf...	[more]
kcnb1	4.402e-26	32.12	potassium voltage-gated channel, Shab-related subf...	[more]
kcnb2	1.052e-25	33.75	potassium voltage-gated channel, Shab-related subf...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNB2	3.815e-24	33.75	potassium channel, voltage gated Shab related subf...	[more]
crisp1.6	1.935e-18	29.89	cysteine-rich secretory protein 1 gene 6 [Source:X...	[more]
KCNS2	1.552e-17	26.42	potassium voltage-gated channel, modifier subfamil...	[more]
sv2b	4.519e-17	31.43	synaptic vesicle glycoprotein 2B [Source:Xenbase;A...	[more]
ENSXETT00000039283.1	5.765e-17	28.74	potassium voltage-gated channel subfamily V member...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kcnb1	8.560e-27	35.00	potassium voltage gated channel, Shab-related subf...	[more]
Kcnb1	8.560e-27	35.00	potassium voltage gated channel, Shab-related subf...	[more]
Kcnb2	2.772e-25	33.75	potassium voltage gated channel, Shab-related subf...	[more]
Kcnb2	2.772e-25	33.75	potassium voltage gated channel, Shab-related subf...	[more]
Kcns1	1.802e-23	30.06	K+ voltage-gated channel, subfamily S, 1 [Source:M...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9MZ19\|KCNB1_RABIT	1.705e-26	35.63	Potassium voltage-gated channel subfamily B member...	[more]
sp\|O18868\|KCNB1_PIG	1.705e-26	35.63	Potassium voltage-gated channel subfamily B member...	[more]
sp\|Q14721\|KCNB1_HUMAN	1.705e-26	35.63	Potassium voltage-gated channel subfamily B member...	[more]
sp\|P17970\|KCNAB_DROME	2.142e-26	35.00	Potassium voltage-gated channel protein Shab OS=Dr...	[more]
sp\|P15387\|KCNB1_RAT	5.987e-26	35.00	Potassium voltage-gated channel subfamily B member...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A448WR55	1.507e-32	39.75	BTB domain-containing protein OS=Protopolystoma xe...	[more]
K1Q9M4	5.945e-29	39.24	Potassium voltage-gated channel protein Shab OS=Cr...	[more]
A0A1S3J453	1.437e-28	36.14	potassium voltage-gated channel subfamily B member...	[more]
A0A0R3T0E4	1.449e-28	36.65	BTB domain-containing protein OS=Rodentolepis nana...	[more]
A0A3P7LGD2	2.132e-28	35.22	BTB domain-containing protein OS=Dibothriocephalus...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNB1	2.711e-27	35.00	potassium voltage-gated channel subfamily B member...	[more]
kcnb1	2.252e-26	32.73	potassium voltage-gated channel subfamily B member...	[more]
si:dkey-192j17.1	2.138e-25	34.18	potassium voltage-gated channel subfamily B member...	[more]
kcnb2	4.081e-25	33.13	potassium voltage-gated channel subfamily B member...	[more]
si:dkey-43k4.5	1.163e-22	32.78	si:dkey-43k4.5 [Source:ZFIN;Acc:ZDB-GENE-120215-82...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000004244.1	7.625e-27	32.30	pep scaffold:Pmarinus_7.0:GL488450:6918:7731:1 gen...	[more]
ENSPMAT00000008567.1	2.887e-26	33.75	pep scaffold:Pmarinus_7.0:GL478165:47990:49229:1 g...	[more]
ENSPMAT00000004235.1	2.898e-25	32.92	pep scaffold:Pmarinus_7.0:GL476413:398954:411573:-...	[more]
ENSPMAT00000001527.1	1.913e-16	29.63	pep scaffold:Pmarinus_7.0:GL482102:431:1368:-1 gen...	[more]
kcnf1b	6.533e-16	28.48	potassium voltage-gated channel, subfamily F, memb...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46844	9.664e-15	26.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45172	1.385e-13	28.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47871	8.231e-12	25.99	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38237	1.517e-11	28.46	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO25793	1.532e-11	28.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnb1	1.769e-27	35.67	potassium voltage-gated channel subfamily B member...	[more]
kcnb1	4.244e-27	34.86	potassium voltage-gated channel subfamily B member...	[more]
kcnb1	7.168e-27	34.29	potassium voltage-gated channel subfamily B member...	[more]
kcnb1	9.393e-27	34.30	potassium voltage-gated channel subfamily B member...	[more]
ENSORLT00000035166.1	2.676e-26	35.00	potassium voltage-gated channel subfamily B member...	[more]

BLAST of Potassium voltage-gated channel protein Shab vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000038809.1	1.191e-122	99.40	SMESG000038809.1	[more]
SMESG000054120.1	6.009e-32	40.00	SMESG000054120.1	[more]
SMESG000004060.1	1.668e-31	36.25	SMESG000004060.1	[more]
SMESG000048635.1	3.966e-30	37.01	SMESG000048635.1	[more]
SMESG000029097.1	1.015e-20	32.32	SMESG000029097.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30030120 ID=SMED30030120|Name=Potassium voltage-gated channel protein Shab|organism=Schmidtea mediterranea sexual|type=transcript|length=815bp
TTTTAATTAATTTTTAGTATTTTTTTAAATGGTTTGTTAAATTCGTTTTA
TATGCATTTTCAAATTGCAAATCTAAATGTAGGTGGCCAATTGTTTAAAG
TTTCATGGAAGATTATACTAAAAAGAGCCTACAGTGTTCGATTATGTCGA
CTTTATTCCGCAATAACTTCGCAACAAATTCTAAAATATTGTGATGATTT
CCAGGCAGATATAGAGGAATATTTCTTCGATAGACATCCGAAATTTTTCA
CTTCGATTCTTCATCTTCTGAAATTTGGAGTTTTCTACGACACGAATACG
ATGTGCGTCATGAGTTTGACAGATGATTTCGAATATTGGGGTATTGATAA
AAATTTGATGTCAAATTGCTGTTTTTATATTTACAATTTGAAATACGATA
TATCAAAGGAAGAATACAATAAAGTTCAAACTATCTATTTAAACAAACTT
AATTATCAACCGGAAAATATTCATGGAAGATGCGCGAAACTTCGAAGTCA
AATATGGGATTTAATGGAAAATCCCGAAAAAAGTAAAAGTGCTCAATTGT
TCAAAAAACAGCTTGGTTGGATTTGTCTGAGAGACGTGATCTAATTTTGG
TACAAAAACTACTGCACACCGAAAATACAAGTTCAACATCGGCTGACGTG
GGTTTGTTTTTTTCTTAATATTTTTCTCGTATAATATTTCGAATTTCTCT
GTGCGTTGACCGGTATTTTTGAAAAGCGAAAATTCTGAATTAAGCGACTT
GAAATTTAATCTTCCAAGTTGTACAGATGACACATTTTCTTGAAGCAGAA
TTTTCAGTTCATCTT

protein sequence of SMED30030120-orf-1

>SMED30030120-orf-1 ID=SMED30030120-orf-1|Name=SMED30030120-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=101bp
DELKILLQENVSSVQLGRLNFKSLNSEFSLFKNTGQRTEKFEILYEKNIK
KKTNPRQPMLNLYFRCAVVFVPKLDHVSQTNPTKLFFEQLSTFTFFGIFH
*

protein sequence of SMED30030120-orf-2

>SMED30030120-orf-2 ID=SMED30030120-orf-2|Name=SMED30030120-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=181bp
MHFQIANLNVGGQLFKVSWKIILKRAYSVRLCRLYSAITSQQILKYCDDF
QADIEEYFFDRHPKFFTSILHLLKFGVFYDTNTMCVMSLTDDFEYWGIDK
NLMSNCCFYIYNLKYDISKEEYNKVQTIYLNKLNYQPENIHGRCAKLRSQ
IWDLMENPEKSKSAQLFKKQLGWICLRDVI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000240	body wall musculature

Vocabulary: **INTERPRO**
Term	Definition
IPR028325	VG_K_chnl
IPR003974	K_chnl_volt-dep_Kv3
IPR003131	T1-type_BTB
IPR011333	SKP1/BTB/POZ_sf

Vocabulary: **biological process**
Term	Definition
GO:0006813	potassium ion transport
GO:0051260	protein homooligomerization
GO:0001508	action potential
GO:0006810	transport
GO:0006811	ion transport
GO:0006887	exocytosis
GO:0006904	vesicle docking involved in exocytosis
GO:0007215	glutamate receptor signaling pathway
GO:0010701	positive regulation of norepinephrine secretion
GO:0031669	cellular response to nutrient levels
GO:0033605	positive regulation of catecholamine secretion
GO:0034765	regulation of ion transmembrane transport
GO:0042593	glucose homeostasis
GO:0045956	positive regulation of calcium ion-dependent exocytosis
GO:0046676	negative regulation of insulin secretion
GO:0055085	transmembrane transport
GO:0071333	cellular response to glucose stimulus
GO:0071805	potassium ion transmembrane transport
GO:0072661	protein targeting to plasma membrane
GO:0090314	positive regulation of protein targeting to membrane
GO:0098900	regulation of action potential
GO:1900454	positive regulation of long term synaptic depression
GO:2000671	regulation of motor neuron apoptotic process

Vocabulary: **molecular function**
Term	Definition
GO:0005249	voltage-gated potassium channel activity
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005267	potassium channel activity
GO:0046982	protein heterodimerization activity

Vocabulary: **cellular component**
Term	Definition
GO:0008076	voltage-gated potassium channel complex
GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016328	lateral plasma membrane
GO:0030054	cell junction
GO:0030424	axon
GO:0030425	dendrite
GO:0032809	neuronal cell body membrane
GO:0042383	sarcolemma
GO:0042995	cell projection
GO:0043005	neuron projection
GO:0043204	perikaryon
GO:0045202	synapse
GO:0045211	postsynaptic membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003974	Potassium channel, voltage dependent, Kv3	PRINTS	PR01498	SHAWCHANNEL	coord: 57..70 score: 63.89 coord: 90..111 score: 33.08
IPR003131	Potassium channel tetramerisation-type BTB domain	PFAM	PF02214	BTB_2	coord: 7..106 e-value: 3.2E-18 score: 65.9
None	No IPR available	GENE3D	G3DSA:3.30.710.10		coord: 4..125 e-value: 5.1E-22 score: 80.1
None	No IPR available	PANTHER	PTHR11537:SF63	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 1	coord: 7..166
None	No IPR available	CDD	cd18378	BTB_POZ_Kv2_KCNB	coord: 6..107 e-value: 2.26937E-29 score: 102.471
IPR028325	Voltage-gated potassium channel	PANTHER	PTHR11537	VOLTAGE-GATED POTASSIUM CHANNEL	coord: 7..166
IPR011333	SKP1/BTB/POZ domain superfamily	SUPERFAMILY	SSF54695	POZ domain	coord: 5..112

Main menu

Potassium voltage-gated channel protein Shab

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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