Mothers against decapentaplegic homolog

Overview


Name	Mothers against decapentaplegic homolog
Smed ID	SMED30030074
Length (bp)	3021

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Mothers against decapentaplegic homolog (SMED30030074) t-SNE clustered cells

Violin plots show distribution of expression levels for Mothers against decapentaplegic homolog (SMED30030074) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Mothers against decapentaplegic homolog (SMED30030074) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Mothers against decapentaplegic homolog (SMED30030074) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030074

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30030074	h1SMcG0002561	SmedASXL_073710	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30030074	h1SMcG0002561	SmedASXL_015153	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
gut	SMED30030074	h1SMcG0002561	SMED30030074	smed_20140614	PMID:25558068 Reuter et al., 2015
cephalic ganglia	SMED30030074	h1SMcG0002561	SMED30030074	smed_20140614	PMID:25558068 Reuter et al., 2015
gut	SMED30030074	h1SMcG0002562	SMED30030074	smed_20140614	PMID:25558068 Reuter et al., 2015
cephalic ganglia	SMED30030074	h1SMcG0002562	SMED30030074	smed_20140614	PMID:25558068 Reuter et al., 2015
head region	SMED30030074	h1SMcG0002561	dd_Smed_v6_20276_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30030074	h1SMcG0002561	dd_Smed_v6_19757_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30030074	h1SMcG0002561	OX_Smed_1.0.11468	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of Mothers against decapentaplegic homolog vs. Ensembl Human
Match: SMAD4 (SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:6770])

HSP 1 Score: 196.438 bits (498), Expect = 8.892e-58
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Human
Match: SMAD4 (SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:6770])

HSP 1 Score: 201.445 bits (511), Expect = 4.352e-57
Identity = 99/127 (77.95%), Postives = 114/127 (89.76%), Query Frame = 1

Query:  250 SSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   12 SNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Human
Match: SMAD4 (SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:6770])

HSP 1 Score: 197.208 bits (500), Expect = 5.219e-54
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 183.341 bits (464), Expect = 3.033e-49
Identity = 83/164 (50.61%), Postives = 115/164 (70.12%), Query Frame = 1

Query: 2050 SDRLVNRMYCSQESLGYPNGLSTDILKMPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            S+R     Y +   L      +T     P++   + +T+ + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  187 SNRASTETYSTPALLAPSESNATSTANFPNIP--VASTTPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 348

HSP 3 Score: 54.6842 bits (130), Expect = 6.676e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  388 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 419

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Human
Match: SMAD4 (SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:6770])

HSP 1 Score: 197.978 bits (502), Expect = 1.675e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.489 bits (454), Expect = 4.096e-47
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 444

HSP 3 Score: 54.6842 bits (130), Expect = 7.194e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  484 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 515

[Close]

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.489 bits (454), Expect = 4.096e-47
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 444

HSP 3 Score: 54.6842 bits (130), Expect = 7.194e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  484 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 515

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Celegans
Match: sma-4 (Dwarfin sma-4 [Source:UniProtKB/Swiss-Prot;Acc:P45897])

HSP 1 Score: 158.688 bits (400), Expect = 1.768e-40
Identity = 74/130 (56.92%), Postives = 92/130 (70.77%), Query Frame = 1

Query:  241 LVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            L  + D+C  I   L   ++ GE   F ++AIESLVKKLKDKR ELDALI AV++ G  PT CVTIQR+LDGRLQVAGRK  PHV+YARIWRWP + KNEL     C    D   +++C+NPYHYER+++
Sbjct:  136 LTTAMDSCQQISHVLQCYQQGGEDSDFVRKAIESLVKKLKDKRIELDALITAVTSNGKQPTGCVTIQRSLDGRLQVAGRKGVPHVVYARIWRWPKVSKNELVKLVQCQTSSD-HPDNICINPYHYERVVS 264

HSP 2 Score: 95.9005 bits (237), Expect = 3.862e-20
Identity = 57/144 (39.58%), Postives = 81/144 (56.25%), Query Frame = 1

Query: 2131 MPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPV-NFLKVSIDGYTDPSSPN--RFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPG-AYIKVFDVRQCYEQI 2550
            +P+   LL N     W +I Y+E+DT +GE FKV   +  KV +DG  DP   N  R  LG L N+HR ++ EKAR++IGRG++L +  DG I I   S   +FV+S YLD+    +     H+  P  +   VFD+R  Y Q+
Sbjct:  335 VPTPPQLLDN-----WCSIIYYELDTPIGETFKVSARDHGKVIVDGGMDPHGENEGRLCLGALSNVHRTEASEKARIHIGRGVELTAHADGNISI--TSNCKIFVRSGYLDYTHGSEYSSKAHRFTPNESSFTVFDIRWAYMQM 471

[Close]

Query:  241 LVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            L  + D+C  I   L   ++ GE   F ++AIESLVKKLKDKR ELDALI AV++ G  PT CVTIQR+LDGRLQVAGRK  PHV+YARIWRWP + KNEL     C    D   +++C+NPYHYER+++
Sbjct:  136 LTTAMDSCQQISHVLQCYQQGGEDSDFVRKAIESLVKKLKDKRIELDALITAVTSNGKQPTGCVTIQRSLDGRLQVAGRKGVPHVVYARIWRWPKVSKNELVKLVQCQTSSD-HPDNICINPYHYERVVS 264

HSP 2 Score: 95.9005 bits (237), Expect = 3.862e-20
Identity = 57/144 (39.58%), Postives = 81/144 (56.25%), Query Frame = 1

Query: 2131 MPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPV-NFLKVSIDGYTDPSSPN--RFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPG-AYIKVFDVRQCYEQI 2550
            +P+   LL N     W +I Y+E+DT +GE FKV   +  KV +DG  DP   N  R  LG L N+HR ++ EKAR++IGRG++L +  DG I I   S   +FV+S YLD+    +     H+  P  +   VFD+R  Y Q+
Sbjct:  335 VPTPPQLLDN-----WCSIIYYELDTPIGETFKVSARDHGKVIVDGGMDPHGENEGRLCLGALSNVHRTEASEKARIHIGRGVELTAHADGNISI--TSNCKIFVRSGYLDYTHGSEYSSKAHRFTPNESSFTVFDIRWAYMQM 471

[Close]

Query:  241 LVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            L  + D+C  I   L   ++ GE   F ++AIESLVKKLKDKR ELDALI AV++ G  PT CVTIQR+LDGRLQVAGRK  PHV+YARIWRWP + KNEL     C    D   +++C+NPYHYER+++
Sbjct:  136 LTTAMDSCQQISHVLQCYQQGGEDSDFVRKAIESLVKKLKDKRIELDALITAVTSNGKQPTGCVTIQRSLDGRLQVAGRKGVPHVVYARIWRWPKVSKNELVKLVQCQTSSD-HPDNICINPYHYERVVS 264

HSP 2 Score: 95.9005 bits (237), Expect = 3.862e-20
Identity = 57/144 (39.58%), Postives = 81/144 (56.25%), Query Frame = 1

Query: 2131 MPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPV-NFLKVSIDGYTDPSSPN--RFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPG-AYIKVFDVRQCYEQI 2550
            +P+   LL N     W +I Y+E+DT +GE FKV   +  KV +DG  DP   N  R  LG L N+HR ++ EKAR++IGRG++L +  DG I I   S   +FV+S YLD+    +     H+  P  +   VFD+R  Y Q+
Sbjct:  335 VPTPPQLLDN-----WCSIIYYELDTPIGETFKVSARDHGKVIVDGGMDPHGENEGRLCLGALSNVHRTEASEKARIHIGRGVELTAHADGNISI--TSNCKIFVRSGYLDYTHGSEYSSKAHRFTPNESSFTVFDIRWAYMQM 471

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Celegans
Match: sma-2 (Dwarfin sma-2 [Source:UniProtKB/Swiss-Prot;Acc:Q02330])

HSP 1 Score: 114.39 bits (285), Expect = 1.036e-26
Identity = 53/115 (46.09%), Postives = 79/115 (68.70%), Query Frame = 1

Query:  286 LTRRKSGESEGFAKRAIESLVKKL-KDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            L  ++  E E +AK+AI++L+KKL K  +  L+ L  A+   G   T+CVTI R+LDGRLQ++ RK  PHVIY R++RWPDL   +ELK  + C + ++  Q+ +C+NPYHY+R+
Sbjct:   14 LKWKQGDEDENWAKKAIDNLMKKLIKHNKQALENLEFALRCQGQQKTECVTIPRSLDGRLQISHRKALPHVIYCRVYRWPDLQSHHELKAIEDCRFCYESGQKDICINPYHYKRV 128

HSP 2 Score: 70.4774 bits (171), Expect = 2.512e-12
Identity = 36/92 (39.13%), Postives = 61/92 (66.30%), Query Frame = 1

Query: 2173 IWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPS-SPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESV-GDGEIWIRCLSGFSVFVQS 2442
             W T+SY+E++T+VGE  +V V+   ++IDG+TDP  + ++ SLG   N++R  ++E  R +IG G+ L  V  +G ++ +C S  ++FVQS
Sbjct:  221 FWATVSYYELNTRVGE--QVKVSSTTITIDGFTDPCINGSKISLGLFSNVNRNATIENTRRHIGNGVKLTYVRSNGSLFAQCESDSAIFVQS 310

[Close]

Query:  286 LTRRKSGESEGFAKRAIESLVKKL-KDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            L  ++  E E +AK+AI++L+KKL K  +  L+ L  A+   G   T+CVTI R+LDGRLQ++ RK  PHVIY R++RWPDL   +ELK  + C + ++  Q+ +C+NPYHY+R+
Sbjct:   14 LKWKQGDEDENWAKKAIDNLMKKLIKHNKQALENLEFALRCQGQQKTECVTIPRSLDGRLQISHRKALPHVIYCRVYRWPDLQSHHELKAIEDCRFCYESGQKDICINPYHYKRV 128

HSP 2 Score: 70.4774 bits (171), Expect = 2.512e-12
Identity = 36/92 (39.13%), Postives = 61/92 (66.30%), Query Frame = 1

Query: 2173 IWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPS-SPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESV-GDGEIWIRCLSGFSVFVQS 2442
             W T+SY+E++T+VGE  +V V+   ++IDG+TDP  + ++ SLG   N++R  ++E  R +IG G+ L  V  +G ++ +C S  ++FVQS
Sbjct:  221 FWATVSYYELNTRVGE--QVKVSSTTITIDGFTDPCINGSKISLGLFSNVNRNATIENTRRHIGNGVKLTYVRSNGSLFAQCESDSAIFVQS 310

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Fly
Match: Med (gene:FBgn0011655 transcript:FBtr0085816)

HSP 1 Score: 228.024 bits (580), Expect = 4.999e-63
Identity = 101/128 (78.91%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESEGFAKRAIESLVKKLK+KRDELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH K+C + FDLK +SVCVNPYHYER+++
Sbjct:   39 TSADACLSIVHSLMCHRQGGESEGFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKYCAFAFDLKCDSVCVNPYHYERVVS 166

HSP 2 Score: 177.563 bits (449), Expect = 6.214e-46
Identity = 80/134 (59.70%), Postives = 100/134 (74.63%), Query Frame = 1

Query: 2149 LLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQI 2550
            L R    + W +I+YFE+DTQVGE FKVP     V IDGY DPS  NRF LG L N+HR +  E+ARL+IG+G+ L+  G+G++W+RCLS  SVFVQSYYLD +A R PG AVHKIYP A IKVFD+RQC++Q+
Sbjct:  463 LSRQPPPEYWCSIAYFELDTQVGETFKVPSAKPNVIIDGYVDPSGGNRFCLGALSNVHRTEQSERARLHIGKGVQLDLRGEGDVWLRCLSDNSVFVQSYYLDREAGRTPGDAVHKIYPAACIKVFDLRQCHQQM 596

HSP 3 Score: 55.4546 bits (132), Expect = 2.260e-7
Identity = 23/32 (71.88%), Postives = 25/32 (78.12%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            +    G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  629 MTAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 660

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Fly
Match: Med (gene:FBgn0011655 transcript:FBtr0085815)

HSP 1 Score: 228.409 bits (581), Expect = 1.361e-62
Identity = 101/128 (78.91%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESEGFAKRAIESLVKKLK+KRDELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH K+C + FDLK +SVCVNPYHYER+++
Sbjct:   39 TSADACLSIVHSLMCHRQGGESEGFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKYCAFAFDLKCDSVCVNPYHYERVVS 166

HSP 2 Score: 177.563 bits (449), Expect = 1.049e-45
Identity = 80/134 (59.70%), Postives = 100/134 (74.63%), Query Frame = 1

Query: 2149 LLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQI 2550
            L R    + W +I+YFE+DTQVGE FKVP     V IDGY DPS  NRF LG L N+HR +  E+ARL+IG+G+ L+  G+G++W+RCLS  SVFVQSYYLD +A R PG AVHKIYP A IKVFD+RQC++Q+
Sbjct:  537 LSRQPPPEYWCSIAYFELDTQVGETFKVPSAKPNVIIDGYVDPSGGNRFCLGALSNVHRTEQSERARLHIGKGVQLDLRGEGDVWLRCLSDNSVFVQSYYLDREAGRTPGDAVHKIYPAACIKVFDLRQCHQQM 670

HSP 3 Score: 55.0694 bits (131), Expect = 2.970e-7
Identity = 23/32 (71.88%), Postives = 25/32 (78.12%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            +    G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  703 MTAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 734

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Fly
Match: Med (gene:FBgn0011655 transcript:FBtr0337030)

HSP 1 Score: 228.409 bits (581), Expect = 1.361e-62
Identity = 101/128 (78.91%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESEGFAKRAIESLVKKLK+KRDELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH K+C + FDLK +SVCVNPYHYER+++
Sbjct:   39 TSADACLSIVHSLMCHRQGGESEGFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKYCAFAFDLKCDSVCVNPYHYERVVS 166

HSP 2 Score: 177.563 bits (449), Expect = 1.049e-45
Identity = 80/134 (59.70%), Postives = 100/134 (74.63%), Query Frame = 1

Query: 2149 LLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQI 2550
            L R    + W +I+YFE+DTQVGE FKVP     V IDGY DPS  NRF LG L N+HR +  E+ARL+IG+G+ L+  G+G++W+RCLS  SVFVQSYYLD +A R PG AVHKIYP A IKVFD+RQC++Q+
Sbjct:  537 LSRQPPPEYWCSIAYFELDTQVGETFKVPSAKPNVIIDGYVDPSGGNRFCLGALSNVHRTEQSERARLHIGKGVQLDLRGEGDVWLRCLSDNSVFVQSYYLDREAGRTPGDAVHKIYPAACIKVFDLRQCHQQM 670

HSP 3 Score: 55.0694 bits (131), Expect = 2.970e-7
Identity = 23/32 (71.88%), Postives = 25/32 (78.12%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            +    G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  703 MTAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 734

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Fly
Match: Mad (gene:FBgn0011648 transcript:FBtr0077616)

HSP 1 Score: 134.42 bits (337), Expect = 4.375e-33
Identity = 62/118 (52.54%), Postives = 85/118 (72.03%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E E +A++A++SLVKKLK ++  ++ L  A+S  G  P+KCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK  + C Y F  KQ+ VC+NPYHY+R+
Sbjct:   28 VKKLLGWKQGDEEEKWAEKAVDSLVKKLKKRKGAIEELERALSCPG-QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRV 144

HSP 2 Score: 82.0333 bits (201), Expect = 7.717e-16
Identity = 45/122 (36.89%), Postives = 75/122 (61.48%), Query Frame = 1

Query: 2173 IWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPS-SPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQ 2535
             W +I+Y+E++ +VGE F    N   V +DG+T+PS + +R  LG+L N++R  ++E  R +IG+G+ L  V  GE++  CLS  ++FVQS   ++     P   V KI PG  +K+F+ ++
Sbjct:  260 FWASIAYYELNCRVGEVFH--CNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRRHIGKGVHLYYV-TGEVYAECLSDSAIFVQSRNCNYHHGFHP-STVCKIPPGCSLKIFNNQE 377

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Fly
Match: Mad (gene:FBgn0011648 transcript:FBtr0332372)

HSP 1 Score: 135.191 bits (339), Expect = 7.534e-33
Identity = 62/118 (52.54%), Postives = 85/118 (72.03%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E E +A++A++SLVKKLK ++  ++ L  A+S  G  P+KCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK  + C Y F  KQ+ VC+NPYHY+R+
Sbjct:   98 VKKLLGWKQGDEEEKWAEKAVDSLVKKLKKRKGAIEELERALSCPG-QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRV 214

HSP 2 Score: 82.4185 bits (202), Expect = 8.612e-16
Identity = 45/122 (36.89%), Postives = 75/122 (61.48%), Query Frame = 1

Query: 2173 IWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPS-SPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQ 2535
             W +I+Y+E++ +VGE F    N   V +DG+T+PS + +R  LG+L N++R  ++E  R +IG+G+ L  V  GE++  CLS  ++FVQS   ++     P   V KI PG  +K+F+ ++
Sbjct:  330 FWASIAYYELNCRVGEVFH--CNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRRHIGKGVHLYYV-TGEVYAECLSDSAIFVQSRNCNYHHGFHP-STVCKIPPGCSLKIFNNQE 447

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Zebrafish
Match: si:dkey-222b8.1 (si:dkey-222b8.1 [Source:ZFIN;Acc:ZDB-GENE-060503-248])

HSP 1 Score: 220.32 bits (560), Expect = 2.555e-61
Identity = 99/128 (77.34%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +S+DACLSIV SL+  R+ GE+E FAKRAIESLVKKLK+KRDELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC Y FDLK ++VCVNPYHYER+++
Sbjct:    7 SSNDACLSIVHSLMCHRQGGENESFAKRAIESLVKKLKEKRDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVS 134

HSP 2 Score: 178.333 bits (451), Expect = 8.189e-47
Identity = 78/125 (62.40%), Postives = 98/125 (78.40%), Query Frame = 1

Query: 2170 DIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + W +ISYFEMD QVGE FKV  N   V++DGY DPS  +RF LG+L N+HR D+ E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYPGA IKVFD+RQC+ 
Sbjct:  337 EFWCSISYFEMDVQVGEMFKVLANCPVVTVDGYVDPSGGDRFCLGQLSNVHRTDASERARLHIGKGVQLECRGEGDVWMRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPGALIKVFDLRQCHR 461

HSP 3 Score: 55.4546 bits (132), Expect = 3.139e-7
Identity = 24/32 (75.00%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  500 LSAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 531

[Close]

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +S+DACLSIV SL+  R+ GE+E FAKRAIESLVKKLK+KRDELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC Y FDLK ++VCVNPYHYER+++
Sbjct:    7 SSNDACLSIVHSLMCHRQGGENESFAKRAIESLVKKLKEKRDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVS 134

HSP 2 Score: 178.333 bits (451), Expect = 8.189e-47
Identity = 78/125 (62.40%), Postives = 98/125 (78.40%), Query Frame = 1

Query: 2170 DIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + W +ISYFEMD QVGE FKV  N   V++DGY DPS  +RF LG+L N+HR D+ E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYPGA IKVFD+RQC+ 
Sbjct:  337 EFWCSISYFEMDVQVGEMFKVLANCPVVTVDGYVDPSGGDRFCLGQLSNVHRTDASERARLHIGKGVQLECRGEGDVWMRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPGALIKVFDLRQCHR 461

HSP 3 Score: 55.4546 bits (132), Expect = 3.139e-7
Identity = 24/32 (75.00%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  500 LSAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 531

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Zebrafish
Match: smad4b (SMAD family member 4b [Source:ZFIN;Acc:ZDB-GENE-060130-140])

HSP 1 Score: 194.897 bits (494), Expect = 7.345e-55
Identity = 99/135 (73.33%), Postives = 118/135 (87.41%), Query Frame = 1

Query:  226 VNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            V+S P   S+DACLSIV SL+  R+ GESE F+KRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C + FDLK ++VCVNPYHYER+++
Sbjct:    3 VSSTP--TSNDACLSIVHSLMCHRQGGESESFSKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQFAFDLKCDNVCVNPYHYERVVS 135

HSP 2 Score: 82.4185 bits (202), Expect = 2.481e-16
Identity = 34/61 (55.74%), Postives = 46/61 (75.41%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKA 2346
            + D W +I+YFEMD QVGE FKVP N   V++DGY DPS  +RF LG+L N+HR +++E+A
Sbjct:  272 APDYWCSIAYFEMDIQVGETFKVPSNCPVVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 332

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Zebrafish
Match: si:dkey-222b8.1 (si:dkey-222b8.1 [Source:ZFIN;Acc:ZDB-GENE-060503-248])

HSP 1 Score: 201.06 bits (510), Expect = 1.384e-54
Identity = 100/128 (78.12%), Postives = 116/128 (90.62%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            NS+DACLSIV SL+  R+ GE+EGFAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC Y FDLK ++VCVNPYHYER+++
Sbjct:    7 NSNDACLSIVHSLMCHRQGGENEGFAKRAIESLVKKLKEKKDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVS 134

HSP 2 Score: 177.178 bits (448), Expect = 2.028e-46
Identity = 78/129 (60.47%), Postives = 100/129 (77.52%), Query Frame = 1

Query: 2158 NTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            +   + W +ISYFEMD QVGE FKV  +   V+IDGY DPS  +RF LG+L N+HR D+ E+ARL+IG+G+ LE  G+G++W+RC+S  +VFVQSYYLD +A R PG AVHKIYPGAYIKVFD+RQC+ 
Sbjct:  336 HPGPEFWCSISYFEMDVQVGEMFKVLSSCPVVTIDGYVDPSGGDRFCLGQLSNVHRTDASERARLHIGKGVQLECRGEGDVWMRCMSDHAVFVQSYYLDREAGRAPGDAVHKIYPGAYIKVFDLRQCHR 464

HSP 3 Score: 55.0694 bits (131), Expect = 3.461e-7
Identity = 24/32 (75.00%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  503 LSAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 534

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Zebrafish
Match: smad4a (SMAD family member 4a [Source:ZFIN;Acc:ZDB-GENE-990603-8])

HSP 1 Score: 195.282 bits (495), Expect = 3.438e-53
Identity = 98/128 (76.56%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C + FDLK +SVCVNPYHYER+++
Sbjct:    8 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQFAFDLKCDSVCVNPYHYERVVS 135

HSP 2 Score: 178.718 bits (452), Expect = 1.987e-47
Identity = 76/129 (58.91%), Postives = 102/129 (79.07%), Query Frame = 1

Query: 2158 NTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  270 HPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 398

HSP 3 Score: 54.299 bits (129), Expect = 5.871e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  437 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 468

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Xenopus
Match: acsl6 (acyl-CoA synthetase long chain family member 6 [Source:Xenbase;Acc:XB-GENE-5834989])

HSP 1 Score: 199.134 bits (505), Expect = 6.941e-55
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:    8 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 135

HSP 2 Score: 167.548 bits (423), Expect = 5.446e-44
Identity = 71/121 (58.68%), Postives = 95/121 (78.51%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFD 2526
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIK+ D
Sbjct:  316 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKLLD 436

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Xenopus
Match: acsl6 (acyl-CoA synthetase long chain family member 6 [Source:Xenbase;Acc:XB-GENE-5834989])

HSP 1 Score: 197.208 bits (500), Expect = 5.000e-54
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 182.57 bits (462), Expect = 5.036e-49
Identity = 82/147 (55.78%), Postives = 109/147 (74.15%), Query Frame = 1

Query: 2101 PNGLSTDILKMPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            PN  S   + +PS       T+ + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  211 PNPTSFSSIPVPS-------TTPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 350

HSP 3 Score: 54.6842 bits (130), Expect = 6.681e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  390 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 421

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Xenopus
Match: acsl6 (acyl-CoA synthetase long chain family member 6 [Source:Xenbase;Acc:XB-GENE-5834989])

HSP 1 Score: 197.978 bits (502), Expect = 8.424e-54
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:    8 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 135

HSP 2 Score: 179.489 bits (454), Expect = 1.593e-47
Identity = 76/129 (58.91%), Postives = 102/129 (79.07%), Query Frame = 1

Query: 2158 NTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  276 HPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 404

HSP 3 Score: 54.6842 bits (130), Expect = 5.876e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  443 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 474

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Xenopus
Match: acsl6 (acyl-CoA synthetase long chain family member 6 [Source:Xenbase;Acc:XB-GENE-5834989])

HSP 1 Score: 197.593 bits (501), Expect = 9.992e-54
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:    8 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 135

HSP 2 Score: 179.489 bits (454), Expect = 1.801e-47
Identity = 76/127 (59.84%), Postives = 101/127 (79.53%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  277 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 403

HSP 3 Score: 54.6842 bits (130), Expect = 6.911e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  442 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 473

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Xenopus
Match: acsl6 (acyl-CoA synthetase long chain family member 6 [Source:Xenbase;Acc:XB-GENE-5834989])

HSP 1 Score: 198.364 bits (503), Expect = 1.380e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.489 bits (454), Expect = 3.079e-47
Identity = 76/127 (59.84%), Postives = 101/127 (79.53%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 445

HSP 3 Score: 54.6842 bits (130), Expect = 6.521e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  484 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 515

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Mouse
Match: Smad4 (SMAD family member 4 [Source:MGI Symbol;Acc:MGI:894293])

HSP 1 Score: 197.978 bits (502), Expect = 1.241e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.874 bits (455), Expect = 1.954e-47
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  318 APEYWCSIAYFEMDVQVGETFKVPSSCPVVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 443

HSP 3 Score: 54.6842 bits (130), Expect = 4.849e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  483 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 514

[Close]

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.874 bits (455), Expect = 1.954e-47
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  318 APEYWCSIAYFEMDVQVGETFKVPSSCPVVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 443

HSP 3 Score: 54.6842 bits (130), Expect = 4.849e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  483 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 514

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Mouse
Match: Smad9 (SMAD family member 9 [Source:MGI Symbol;Acc:MGI:1859993])

HSP 1 Score: 121.324 bits (303), Expect = 1.082e-28
Identity = 64/120 (53.33%), Postives = 85/120 (70.83%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            V+ LL  ++  E E +A++A++SLVKKLK K+  +D L  A+S  G  P+KCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK  + C + F  KQ+ VC+NPYHY R+ T
Sbjct:   18 VKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQ-PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVET 136

HSP 2 Score: 89.7373 bits (221), Expect = 2.940e-18
Identity = 52/137 (37.96%), Postives = 84/137 (61.31%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSS-PNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLKM 2583
            W +++Y+E++ +VGE F+   +   V IDG+TDPS+  NRF LG L N++R  ++E  R +IG+G+ L  VG GE++  C+S  S+FVQS   +++    P   V KI  G  +KVF+  Q + Q+ A  + H  ++
Sbjct:  236 WCSVAYYELNNRVGETFQA--SSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECVSDSSIFVQSRNCNYQHGFHP-ATVCKIPSGCSLKVFN-NQLFAQLLAQSVHHGFEV 367

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Mouse
Match: Smad5 (SMAD family member 5 [Source:MGI Symbol;Acc:MGI:1328787])

HSP 1 Score: 120.553 bits (301), Expect = 3.371e-28
Identity = 61/118 (51.69%), Postives = 85/118 (72.03%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E E +A++A+++LVKKLK K+  ++ L  A+S+ G  P+KCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK    C + F  KQ+ VC+NPYHY+R+
Sbjct:   15 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG-QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRV 131

HSP 2 Score: 81.2629 bits (199), Expect = 1.784e-15
Identity = 50/133 (37.59%), Postives = 77/133 (57.89%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSS-PNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEH 2571
            W +I Y+E++ +VGE F    +   V +DG+TDPS+  +RF LG L N++R  ++E  R +IG+G+ L  VG GE++  CLS  S+FVQS   +      P   V KI     +K+F+  Q + Q+ A  + H
Sbjct:  271 WCSIVYYELNNRVGEAFHA--SSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNFHHGFHP-TTVCKIPSSCSLKIFN-NQEFAQLLAQSVNH 398

[Close]

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E E +A++A+++LVKKLK K+  ++ L  A+S+ G  P+KCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK    C + F  KQ+ VC+NPYHY+R+
Sbjct:   15 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG-QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRV 131

HSP 2 Score: 81.2629 bits (199), Expect = 1.784e-15
Identity = 50/133 (37.59%), Postives = 77/133 (57.89%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSS-PNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEH 2571
            W +I Y+E++ +VGE F    +   V +DG+TDPS+  +RF LG L N++R  ++E  R +IG+G+ L  VG GE++  CLS  S+FVQS   +      P   V KI     +K+F+  Q + Q+ A  + H
Sbjct:  271 WCSIVYYELNNRVGEAFHA--SSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNFHHGFHP-TTVCKIPSSCSLKIFN-NQEFAQLLAQSVNH 398

[Close]

BLAST of Mothers against decapentaplegic homolog vs. UniProt/SwissProt
Match: sp|Q13485|SMAD4_HUMAN (Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 8.044e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.489 bits (454), Expect = 1.967e-46
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 444

HSP 3 Score: 54.6842 bits (130), Expect = 3.455e-6
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  484 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 515

[Close]

BLAST of Mothers against decapentaplegic homolog vs. UniProt/SwissProt
Match: sp|P97471|SMAD4_MOUSE (Mothers against decapentaplegic homolog 4 OS=Mus musculus OX=10090 GN=Smad4 PE=1 SV=2)

HSP 1 Score: 197.978 bits (502), Expect = 8.680e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.874 bits (455), Expect = 1.367e-46
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  318 APEYWCSIAYFEMDVQVGETFKVPSSCPVVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 443

HSP 3 Score: 54.6842 bits (130), Expect = 3.392e-6
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  483 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 514

[Close]

BLAST of Mothers against decapentaplegic homolog vs. UniProt/SwissProt
Match: sp|Q1HE26|SMAD4_BOVIN (Mothers against decapentaplegic homolog 4 OS=Bos taurus OX=9913 GN=SMAD4 PE=2 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 9.019e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.489 bits (454), Expect = 1.927e-46
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  320 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 445

HSP 3 Score: 54.6842 bits (130), Expect = 3.580e-6
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  485 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 516

[Close]

BLAST of Mothers against decapentaplegic homolog vs. UniProt/SwissProt
Match: sp|O70437|SMAD4_RAT (Mothers against decapentaplegic homolog 4 OS=Rattus norvegicus OX=10116 GN=Smad4 PE=1 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 9.548e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.874 bits (455), Expect = 1.527e-46
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 444

HSP 3 Score: 54.6842 bits (130), Expect = 3.367e-6
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  484 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 515

[Close]

BLAST of Mothers against decapentaplegic homolog vs. UniProt/SwissProt
Match: sp|Q9GKQ9|SMAD4_PIG (Mothers against decapentaplegic homolog 4 OS=Sus scrofa OX=9823 GN=SMAD4 PE=2 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 9.732e-53
Identity = 99/128 (77.34%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138

HSP 2 Score: 179.489 bits (454), Expect = 1.860e-46
Identity = 76/126 (60.32%), Postives = 101/126 (80.16%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCY 2541
            + + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+
Sbjct:  319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCH 444

HSP 3 Score: 54.6842 bits (130), Expect = 3.545e-6
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  484 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 515

[Close]

BLAST of Mothers against decapentaplegic homolog vs. TrEMBL
Match: A0A1S3JD31 (mothers against decapentaplegic homolog 4-like OS=Lingula unguis OX=7574 GN=LOC106172162 PE=4 SV=1)

HSP 1 Score: 230.335 bits (586), Expect = 2.929e-66
Identity = 103/128 (80.47%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+KRDELD+LI A++T G HPTKCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH KFC + FDLKQ+SVCVNPYHYER+++
Sbjct:    9 TSADACLSIVHSLMCHRQGGESESFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPTKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHAKFCQFAFDLKQDSVCVNPYHYERVVS 136

[Close]

BLAST of Mothers against decapentaplegic homolog vs. TrEMBL
Match: A0A0L8GJZ2 (MH1 domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22032358mg PE=4 SV=1)

HSP 1 Score: 227.639 bits (579), Expect = 9.059e-66
Identity = 103/128 (80.47%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+KRDELD+LI A++T G HPTKCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH KFC Y FDLK +SVCVNPYHYER+++
Sbjct:   11 TSADACLSIVHSLMCHRQGGESESFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPTKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHAKFCQYAFDLKADSVCVNPYHYERVVS 138

[Close]

BLAST of Mothers against decapentaplegic homolog vs. TrEMBL
Match: A0A433SJV6 (MH1 domain-containing protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_022999 PE=4 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 4.626e-65
Identity = 101/128 (78.91%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+KRDELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH KFC + FDLKQ+SVC+NPYHYER+++
Sbjct:    4 TSADACLSIVHSLMCHRQGGESESFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKFCQFAFDLKQDSVCINPYHYERVVS 131

[Close]

BLAST of Mothers against decapentaplegic homolog vs. TrEMBL
Match: A0A1Y1M7Z1 (MH1 domain-containing protein OS=Photinus pyralis OX=7054 PE=4 SV=1)

HSP 1 Score: 228.024 bits (580), Expect = 5.730e-65
Identity = 105/142 (73.94%), Postives = 121/142 (85.21%), Query Frame = 1

Query:  205 FTMFTQPVNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            F+M    +N+     S+DACLSIV SLL  R+ GESEGF+KRAIESLVKKLK+KRDELD+LI A++T G HPTKCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH K+C + FDLK +SVCVNPYHYER+++
Sbjct:    4 FSMANLSINA---PTSADACLSIVHSLLCHRQGGESEGFSKRAIESLVKKLKEKRDELDSLITAITTNGAHPTKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKYCQFAFDLKCDSVCVNPYHYERVVS 142

[Close]

BLAST of Mothers against decapentaplegic homolog vs. TrEMBL
Match: W8C7B7 (Mothers against decapentaplegic-4 OS=Ceratitis capitata OX=7213 GN=SMAD4 PE=2 SV=1)

HSP 1 Score: 228.024 bits (580), Expect = 1.062e-64
Identity = 107/150 (71.33%), Postives = 125/150 (83.33%), Query Frame = 1

Query:  202 QFTMFTQ--PVNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIITAPFNV 645
            Q T+  Q  P ++ P   S+DACLSIV SL+  R+ GESEGFAKRAIESLVKKLK+KRDELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++   ++
Sbjct:   23 QDTLMVQMPPPSNAP--TSADACLSIVHSLMCHRQGGESEGFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKYCAYAFDLKCDSVCVNPYHYERVVSPGIDL 170

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Cavefish
Match: ENSAMXT00000041590.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000517.1:30204:35830:-1 gene:ENSAMXG00000033137.1 transcript:ENSAMXT00000041590.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 199.134 bits (505), Expect = 3.143e-58
Identity = 100/128 (78.12%), Postives = 116/128 (90.62%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +SSDACLSIV SL+  R+ GE+EGFAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC Y FDLK ++VCVNPYHYER+++
Sbjct:    6 SSSDACLSIVHSLMCHRQGGENEGFAKRAIESLVKKLKEKKDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVS 133

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Cavefish
Match: smad4b (SMAD family member 4b [Source:ZFIN;Acc:ZDB-GENE-060130-140])

HSP 1 Score: 196.438 bits (498), Expect = 2.642e-57
Identity = 101/133 (75.94%), Postives = 116/133 (87.22%), Query Frame = 1

Query:  226 VNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+S P   S+DACLSIV SL+  R+ GESE F+KRAIESLVKKLK+K+DELD+LI AV+T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH K+C + FDLK +SVCVNPYHYER+
Sbjct:    3 VSSTP--TSNDACLSIVHSLMCHRQGGESESFSKRAIESLVKKLKEKKDELDSLITAVTTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQFAFDLKCDSVCVNPYHYERV 133

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Cavefish
Match: si:dkey-222b8.1 (si:dkey-222b8.1 [Source:ZFIN;Acc:ZDB-GENE-060503-248])

HSP 1 Score: 198.749 bits (504), Expect = 7.103e-55
Identity = 100/128 (78.12%), Postives = 116/128 (90.62%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            NS+DACLSIV SL+  R+ GE+EGFAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC Y FDLK ++VCVNPYHYER+++
Sbjct:    7 NSNDACLSIVHSLMCHRQGGENEGFAKRAIESLVKKLKEKKDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVS 134

HSP 2 Score: 177.948 bits (450), Expect = 1.021e-47
Identity = 79/131 (60.31%), Postives = 101/131 (77.10%), Query Frame = 1

Query: 2152 LRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            L  T  + W +ISYFEMD QVGE FKV  +   V++DGY DPS  +RF LG+L N+HR D+ E+ARL+IG+G+ LE  G+G++W+RC+S  +VFVQSYYLD +A R PG AVHKIYPGAYIKVFD+RQC+ 
Sbjct:  217 LSPTGPEFWCSISYFEMDVQVGEMFKVLSSCPVVTVDGYVDPSGGDRFCLGQLSNVHRTDASERARLHIGKGVQLECRGEGDVWMRCMSDHAVFVQSYYLDREAGRAPGDAVHKIYPGAYIKVFDLRQCHR 347

HSP 3 Score: 54.6842 bits (130), Expect = 3.616e-7
Identity = 24/32 (75.00%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  386 LSAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 417

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Cavefish
Match: si:dkey-222b8.1 (mothers against decapentaplegic homolog 4-like [Source:NCBI gene;Acc:103022359])

HSP 1 Score: 200.675 bits (509), Expect = 1.942e-54
Identity = 100/128 (78.12%), Postives = 116/128 (90.62%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +SSDACLSIV SL+  R+ GE+EGFAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC Y FDLK ++VCVNPYHYER+++
Sbjct:    6 SSSDACLSIVHSLMCHRQGGENEGFAKRAIESLVKKLKEKKDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVS 133

HSP 2 Score: 181.415 bits (459), Expect = 7.155e-48
Identity = 79/125 (63.20%), Postives = 99/125 (79.20%), Query Frame = 1

Query: 2170 DIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + W +ISYFEMD QVGE FKV  N   V++DGY DPS  +RF LG+L N+HR D+ E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYPGAYIKVFD+RQC+ 
Sbjct:  341 EFWCSISYFEMDIQVGEMFKVLANCPMVTVDGYVDPSGGDRFCLGQLSNVHRTDASERARLHIGKGVQLECRGEGDVWMRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPGAYIKVFDLRQCHR 465

HSP 3 Score: 54.299 bits (129), Expect = 5.734e-7
Identity = 23/32 (71.88%), Postives = 25/32 (78.12%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
             +   G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  504 FSAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 535

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Cavefish
Match: si:dkey-222b8.1 (mothers against decapentaplegic homolog 4-like [Source:NCBI gene;Acc:103022359])

HSP 1 Score: 200.675 bits (509), Expect = 2.325e-54
Identity = 100/128 (78.12%), Postives = 116/128 (90.62%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +SSDACLSIV SL+  R+ GE+EGFAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC Y FDLK ++VCVNPYHYER+++
Sbjct:   21 SSSDACLSIVHSLMCHRQGGENEGFAKRAIESLVKKLKEKKDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVS 148

HSP 2 Score: 181.415 bits (459), Expect = 8.529e-48
Identity = 79/125 (63.20%), Postives = 99/125 (79.20%), Query Frame = 1

Query: 2170 DIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + W +ISYFEMD QVGE FKV  N   V++DGY DPS  +RF LG+L N+HR D+ E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYPGAYIKVFD+RQC+ 
Sbjct:  356 EFWCSISYFEMDIQVGEMFKVLANCPMVTVDGYVDPSGGDRFCLGQLSNVHRTDASERARLHIGKGVQLECRGEGDVWMRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPGAYIKVFDLRQCHR 480

HSP 3 Score: 54.299 bits (129), Expect = 5.673e-7
Identity = 23/32 (71.88%), Postives = 25/32 (78.12%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
             +   G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  519 FSAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 550

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010406.1 (pep scaffold:Pmarinus_7.0:GL476769:63937:79511:-1 gene:ENSPMAG00000009414.1 transcript:ENSPMAT00000010406.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 224.172 bits (570), Expect = 2.261e-63
Identity = 101/128 (78.91%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +S+DACLSIV SLL  R+ GESE FAKRAIESLV+KLK+K+DELD+LI AV+T G HP+KCVTIQRTLDGRLQVAGRK FPHV+YARIWRWPDLHKNELKH KFC Y FDLK +SVCVNPYHYER+++
Sbjct:   10 SSNDACLSIVHSLLCHRQGGESETFAKRAIESLVRKLKEKKDELDSLITAVTTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVVYARIWRWPDLHKNELKHVKFCQYAFDLKADSVCVNPYHYERVVS 137

HSP 2 Score: 183.726 bits (465), Expect = 2.128e-49
Identity = 80/132 (60.61%), Postives = 102/132 (77.27%), Query Frame = 1

Query: 2149 LLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            L  +   + W +I+YFEMD QVGE FKVP +   V++DGY DPS  +RF LG+L N+HR D+ EKARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYPGAYIKVFD+RQC+ 
Sbjct:  329 LSTHPGPEFWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTDASEKARLHIGKGVQLECRGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPGAYIKVFDLRQCHR 460

HSP 3 Score: 54.6842 bits (130), Expect = 9.099e-8
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  499 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 530

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Sea Lamprey
Match: smad4a (SMAD family member 4a [Source:ZFIN;Acc:ZDB-GENE-990603-8])

HSP 1 Score: 201.445 bits (511), Expect = 3.247e-58
Identity = 100/128 (78.12%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE F+KRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNELKH KFC Y FDLK +SVCVNPYHYER+++
Sbjct:   10 TSNDACLSIVHSLMCHRQGGESESFSKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHLKFCQYAFDLKADSVCVNPYHYERVVS 137

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Sea Lamprey
Match: smad9 (SMAD family member 9 [Source:ZFIN;Acc:ZDB-GENE-031014-1])

HSP 1 Score: 123.25 bits (308), Expect = 7.077e-30
Identity = 64/118 (54.24%), Postives = 86/118 (72.88%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E E +A++A++SLVKKLK K+  L+ L  A+ST G  P+KCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK  + C + F  KQ+ VC+NPYHY+R+
Sbjct:   15 VKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGALEELEKALSTPGQ-PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRV 131

HSP 2 Score: 80.8777 bits (198), Expect = 4.654e-16
Identity = 50/136 (36.76%), Postives = 78/136 (57.35%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSS-PNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLK 2580
            W +I Y+E+  +VGE F    +   V +DG+TDPS+  NRF LG L +++R  ++E  R +IG+G+ L  VG GE++  CLS  S+FVQS   ++     P   V KI  G  +K+F+  Q +  + A  + H  +
Sbjct:  269 WCSIVYYELTNRVGEAFHA--SSTSVLVDGFTDPSNNKNRFCLGLLSHVNRNSTIENTRRHIGKGVHLYYVG-GEVFAECLSDSSIFVQSRNCNYHHGFHP-TTVCKIPSGCSLKIFN-NQEFAGLLAESVNHGFE 399

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010514.1 (pep scaffold:Pmarinus_7.0:GL482855:12566:14836:-1 gene:ENSPMAG00000009525.1 transcript:ENSPMAT00000010514.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.145 bits (261), Expect = 3.577e-26
Identity = 45/69 (65.22%), Postives = 57/69 (82.61%), Query Frame = 1

Query: 2338 EKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            +  RL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYPGAYIKVFD+RQC+ 
Sbjct:    1 DAGRLHIGKGVQLECRGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPGAYIKVFDLRQCHR 69

HSP 2 Score: 53.9138 bits (128), Expect = 1.565e-8
Identity = 24/32 (75.00%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  108 LSAAAGIGVDDLRRLCILRLSFVKGWGPDYPR 139

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Sea Lamprey
Match: SMAD3 (SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769])

HSP 1 Score: 106.686 bits (265), Expect = 1.578e-24
Identity = 59/124 (47.58%), Postives = 78/124 (62.90%), Query Frame = 1

Query:  271 IVQSLLTRRKSGESEGFAKRAIES---LVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +V+ LL  ++ GE  G   +  E     + K   K  +LD L  A++ A N  TKC+TI R+LDGRLQV+ RK  PHVIY R+WRWPDLH  +EL     C + F LK++ VCVNPYHY+R+ T
Sbjct:   11 VVKRLLGWKR-GEPGGLEDKWSEKAVKSLVKKLKKSGQLDELERAIA-AQNSSTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELHAIDACEFAFHLKKDEVCVNPYHYQRVET 132

HSP 2 Score: 92.8189 bits (229), Expect = 4.576e-20
Identity = 49/118 (41.53%), Postives = 74/118 (62.71%), Query Frame = 1

Query: 2173 IWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFD 2526
             W +ISY+E++ +VGE F    +   +++DG+TDPS+  RF LG L NI+R  +VE  R +IGRG+ L  +G GE++  CLS  ++FVQS   + +    P   V KI PG  +K+F+
Sbjct:  240 FWCSISYYELNQRVGETFHA--SQPSLTVDGFTDPSNSERFCLGLLSNINRNQTVEMTRRHIGRGVRLYYIG-GEVFAECLSESAIFVQSPNCNQRYGWHP-ATVCKIPPGCNLKIFN 353

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Nematostella
Match: EDO31382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SY32])

HSP 1 Score: 197.208 bits (500), Expect = 2.689e-55
Identity = 98/128 (76.56%), Postives = 115/128 (89.84%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             SSDACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A+++AG HP+KCVTIQRTLDGRLQVAGRK FPHVIYARIWRWPDLHKNEL+H K+C + FDLK +SVCVNP+HYER+++
Sbjct:    6 TSSDACLSIVHSLMCHRQGGESEAFAKRAIESLVKKLKEKKDELDSLITAITSAGTHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELRHVKYCQFAFDLKCDSVCVNPFHYERVVS 133

HSP 2 Score: 170.244 bits (430), Expect = 4.497e-46
Identity = 84/168 (50.00%), Postives = 112/168 (66.67%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLKMRMSPISPMNSHLSDIKLLSP-YSKTCIEDQPC 2676
            W +I+YFE+D QVGE FKV  N   V++DGY DPS  NRF LG+L N+HR ++ E+ARL+IG+G+ L+  G+G++W+RCLS  SVFVQSYYLD +A R PG AVHKIYP AYIKVFD+R    Q+    +      R+  +      LS +K   P Y +  I++ PC
Sbjct:  209 WCSIAYFELDQQVGEIFKVTSNCPSVTVDGYVDPSGGNRFCLGQLSNVHRTEASERARLHIGKGVQLDVRGEGDVWVRCLSEHSVFVQSYYLDREAGRCPGDAVHKIYPSAYIKVFDLRALLPQMGQTSVGVDDLRRLCIL-----RLSFVKGWGPDYPRKSIKETPC 371

HSP 3 Score: 52.373 bits (124), Expect = 5.591e-7
Identity = 23/28 (82.14%), Postives = 24/28 (85.71%), Query Frame = 3

Query: 2937 TGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            T + VDDL  LCILRLSFVKGWGPDYPR
Sbjct:  336 TSVGVDDLRRLCILRLSFVKGWGPDYPR 363

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Nematostella
Match: EDO37590 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFA8])

HSP 1 Score: 180.259 bits (456), Expect = 4.797e-53
Identity = 79/110 (71.82%), Postives = 92/110 (83.64%), Query Frame = 1

Query:  295 RKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            R+ GE+E FAKRAIESLVKKL+ K DEL++LI  ++T G  P+KCVTIQRTLDGRLQV  RK FPHVIYAR+WRWPD+ K E+KH  FC +G+DLK ESVCVNPYHYERI
Sbjct:    1 RQGGETEKFAKRAIESLVKKLRKKTDELESLISTITTNGAQPSKCVTIQRTLDGRLQVCERKGFPHVIYARLWRWPDIQKMEMKHLDFCRFGYDLKYESVCVNPYHYERI 110

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Nematostella
Match: EDO37591 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFA9])

HSP 1 Score: 160.229 bits (404), Expect = 4.582e-46
Identity = 67/109 (61.47%), Postives = 91/109 (83.49%), Query Frame = 1

Query:  298 KSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            +S E++ F++RAIESLVKKLK K  ELD+LI+A+++ G   +KCVT+ RT+DGRLQV  +K FPHVIYAR+WRWPD+HK E++H ++C +G+DLK E VCVNPYHY+R+
Sbjct:    1 QSVEADSFSRRAIESLVKKLKKKFYELDSLIIAITSKGRTASKCVTVPRTMDGRLQVGEKKDFPHVIYARLWRWPDVHKMEMRHKEYCQFGYDLKNEKVCVNPYHYDRV 109

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Nematostella
Match: EDO47037 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNC1])

HSP 1 Score: 122.865 bits (307), Expect = 9.937e-30
Identity = 66/118 (55.93%), Postives = 84/118 (71.19%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E E +A++AIESLVKKLK K+  L+ L  A+S   N  +KCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK  + C Y F LKQ+ VC+NPYHY R+
Sbjct:   12 VKRLLGWKQGDEEEKWAEKAIESLVKKLKKKKGALEDLEKALSNP-NQQSKCVTIARSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEYAFGLKQKEVCINPYHYHRV 128

HSP 2 Score: 86.2705 bits (212), Expect = 1.161e-17
Identity = 55/154 (35.71%), Postives = 85/154 (55.19%), Query Frame = 1

Query: 2101 PNGLSTDILKMP-----SLESLLRNTSTDI-----WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPN--RFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFD 2526
            PN +  D +  P     S E++   T+ +      W +I+Y+E++ +VGE F      L V  DG+TDP++ N  RF LG L N++R  ++E  R +IG+G+ L  VG GE++  CLS  ++FVQS   +H     P   V KI  G  +K+F+
Sbjct:  205 PNAMDVDPVNSPPSISQSAEAMSHVTAVNYQEPLSWCSIAYYELNNRVGELFHAKSTSLIV--DGFTDPNTTNSERFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSAIFVQSRNCNHSHGFHP-TTVCKIPSGCTLKIFN 354

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Nematostella
Match: EDO39594 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9L0])

HSP 1 Score: 105.145 bits (261), Expect = 7.620e-24
Identity = 54/121 (44.63%), Postives = 75/121 (61.98%), Query Frame = 1

Query:  271 IVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
            +V+ LL  ++ G+ +          + K   K   L+ L  A++  G   TKCVTI R+LDGRLQV+ RK  PHVIY R+WRWPDL   +EL+  + C + F LK+E VCVNP+HY+R+ T
Sbjct:   11 VVKRLLGWKRGGDEDDKWAEKAVKSLVKKLKKTGGLEELEKAITNPGVA-TKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLQSHHELRPIEACEFAFSLKKEEVCVNPFHYQRVET 130

HSP 2 Score: 96.6709 bits (239), Expect = 4.032e-21
Identity = 52/125 (41.60%), Postives = 78/125 (62.40%), Query Frame = 1

Query: 2152 LRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFD 2526
            ++ T    W +ISY+EM+T+VGE F    +   +++DG+TDPSS +RF LG L NI+R   +E  R +IG+G+ L  +G GE++  CLS  S+FVQS   + +    P   V KI PG  +K+F+
Sbjct:  222 IQYTEPTYWCSISYYEMNTRVGETFHA--SQPSLTVDGFTDPSSSDRFCLGLLSNINRNPPIEMTRKHIGKGVRLYYIG-GEVFAECLSDSSIFVQSPNCNQRYNWHP-ATVCKIPPGCNLKIFN 342

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Medaka
Match: ENSORLT00000027726.1 (mothers against decapentaplegic homolog 4 [Source:NCBI gene;Acc:101173916])

HSP 1 Score: 201.445 bits (511), Expect = 5.379e-55
Identity = 101/133 (75.94%), Postives = 117/133 (87.97%), Query Frame = 1

Query:  238 PLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIITAP 636
            P  +S+DACLSIV SL+  R+ GE+EGFAKRAIESLVKKLK+K+DELD+LI A+++ G HP+KCVTIQRTLDGRLQVAGRK FPHVIYAR+WRWPDLHKNELKH KFC + FDLK +SVCVNPYHYER+  AP
Sbjct:    6 PAPSSADACLSIVHSLMCHRQGGENEGFAKRAIESLVKKLKEKKDELDSLITAITSNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQFAFDLKYDSVCVNPYHYERVAAAP 138

HSP 2 Score: 173.326 bits (438), Expect = 1.765e-45
Identity = 77/137 (56.20%), Postives = 100/137 (72.99%), Query Frame = 1

Query: 2134 PSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            P  + +  +   + W +ISYFE+D QVGE FKV  +   V++DGY DPS  +RF LG+L N+HR  +  +ARL+IGRG+ LE  G+G++W+RCLS  SVFVQSYYLD +A R PG  VHKIYPGAYIKVFD+RQC+ 
Sbjct:  297 PYPQPVSNHPGPEFWCSISYFELDVQVGEIFKVQSSCPLVTVDGYVDPSGGDRFCLGQLSNVHRTAASHRARLHIGRGVQLECRGEGDVWMRCLSDHSVFVQSYYLDREAGRVPGDGVHKIYPGAYIKVFDLRQCHR 433

HSP 3 Score: 50.447 bits (119), Expect = 8.868e-6
Identity = 22/32 (68.75%), Postives = 25/32 (78.12%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            ++   GL VDDL  LCI+RLSFVKGWG DYPR
Sbjct:  472 VSSPAGLGVDDLRRLCIVRLSFVKGWGSDYPR 503

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Medaka
Match: smad4b (mothers against decapentaplegic homolog 4 [Source:NCBI gene;Acc:101163504])

HSP 1 Score: 195.667 bits (496), Expect = 7.738e-54
Identity = 98/128 (76.56%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHV+YAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:   13 TSNDACLSIVHSLMCHRQGGESESFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVVYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 140

HSP 2 Score: 177.948 bits (450), Expect = 9.775e-48
Identity = 76/127 (59.84%), Postives = 100/127 (78.74%), Query Frame = 1

Query: 2164 STDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + W +I+YFEMD QVGE FKVP     V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  217 TPEYWCSIAYFEMDVQVGETFKVPSTCPVVTVDGYVDPSGGDRFCLGQLSNVHRTENIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 343

HSP 3 Score: 53.9138 bits (128), Expect = 5.545e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  382 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 413

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Medaka
Match: smad4b (mothers against decapentaplegic homolog 4 [Source:NCBI gene;Acc:101163504])

HSP 1 Score: 195.667 bits (496), Expect = 2.101e-53
Identity = 98/128 (76.56%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHV+YAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:    8 TSNDACLSIVHSLMCHRQGGESESFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVVYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 135

HSP 2 Score: 177.948 bits (450), Expect = 3.060e-47
Identity = 76/129 (58.91%), Postives = 101/129 (78.29%), Query Frame = 1

Query: 2158 NTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + + W +I+YFEMD QVGE FKVP     V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  268 HPAPEYWCSIAYFEMDVQVGETFKVPSTCPVVTVDGYVDPSGGDRFCLGQLSNVHRTENIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 396

HSP 3 Score: 54.299 bits (129), Expect = 5.009e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  435 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 466

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Medaka
Match: smad4b (mothers against decapentaplegic homolog 4 [Source:NCBI gene;Acc:101163504])

HSP 1 Score: 195.282 bits (495), Expect = 2.642e-53
Identity = 98/128 (76.56%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHV+YAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:    8 TSNDACLSIVHSLMCHRQGGESESFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVVYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 135

HSP 2 Score: 177.563 bits (449), Expect = 2.938e-47
Identity = 76/129 (58.91%), Postives = 101/129 (78.29%), Query Frame = 1

Query: 2158 NTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + + W +I+YFEMD QVGE FKVP     V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  258 HPAPEYWCSIAYFEMDVQVGETFKVPSTCPVVTVDGYVDPSGGDRFCLGQLSNVHRTENIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 386

HSP 3 Score: 54.299 bits (129), Expect = 5.519e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  425 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 456

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Medaka
Match: smad4b (mothers against decapentaplegic homolog 4 [Source:NCBI gene;Acc:101163504])

HSP 1 Score: 195.667 bits (496), Expect = 3.437e-53
Identity = 98/128 (76.56%), Postives = 114/128 (89.06%), Query Frame = 1

Query:  247 NSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIIT 630
             S+DACLSIV SL+  R+ GESE FAKRAIESLVKKLK+K+DELD+LI A++T G HP+KCVTIQRTLDGRLQVAGRK FPHV+YAR+WRWPDLHKNELKH K+C Y FDLK +SVCVNPYHYER+++
Sbjct:    8 TSNDACLSIVHSLMCHRQGGESESFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVVYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 135

HSP 2 Score: 177.563 bits (449), Expect = 6.798e-47
Identity = 76/129 (58.91%), Postives = 101/129 (78.29%), Query Frame = 1

Query: 2158 NTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYE 2544
            + + + W +I+YFEMD QVGE FKVP     V++DGY DPS  +RF LG+L N+HR +++E+ARL+IG+G+ LE  G+G++W+RCLS  +VFVQSYYLD +A R PG AVHKIYP AYIKVFD+RQC+ 
Sbjct:  268 HPAPEYWCSIAYFEMDVQVGETFKVPSTCPVVTVDGYVDPSGGDRFCLGQLSNVHRTENIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 396

HSP 3 Score: 54.299 bits (129), Expect = 5.559e-7
Identity = 23/32 (71.88%), Postives = 26/32 (81.25%), Query Frame = 3

Query: 2925 LARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            L+   G+ VDDL  LCILR+SFVKGWGPDYPR
Sbjct:  435 LSAAAGIGVDDLRRLCILRMSFVKGWGPDYPR 466

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Planmine SMEST
Match: SMESG000029614.1 (SMESG000029614.1)

HSP 1 Score: 1540.4 bits (3987), Expect = 0.000e+0
Identity = 840/857 (98.02%), Postives = 841/857 (98.13%), Query Frame = 1

Query:  211 MFTQPVNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIITAPFNVFAXXXXXXXXXXXXXXXXXXEINGIIGNTMPQHGSYHLNPNSSIHRLTGSMXXXXXXXXXXXXXXXMGLNFRSTAIGSNVQQNGLGMSSSESSPTAINSPISHVRPFLPIPPGVLNPFYSRSLLHHINSNEFKLHNDGYRNQYSNIYSQNSLSYPSLGSDSRIYPPRFSRGMVEELTAYSRSMIGXXXXXXXXXXXXXTLGGMTHLDNYSYNRHDQSSTVTDENETTDNIKRNHGTYKKSSSPNVDLNVSHNDDKDSTSEISVCSEDNDQQLVSSSIVNGRVTQSPQLNSVFRKRTLSMSDSNSKLVDENTIMQKRCRSMYKAEETIKTEEVCHSIDIIKSEAHSHSYPKSMTNEAEYLSDSLSEIQXXXXXXXXXXXXXXXXXXXXXAPILNSSWNIIPRLQSVDKDLHIDINSRYSYQLDPCSEIKLSRSQFDNAMSAKKAVGLDNNNSISHDYYLHHQNQDLRIDSDRLVNRMYCSQESLGYPNGLSTDILKMPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLKMRMSPISPMNSHLSDIKLLSPYSKTCIEDQPCSDSGSASTGIINVDENVSPDXXXXXXXXXXXXXDK 2781
            MFTQPVNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIITAPFNVFASTNTGNHHHHSNHSSTHGEINGIIGNTMPQHGSYHLNPNSSIHRLTGSMHNSNSSAHHHNLSTNMGLNFRSTAIGSNVQQNGLGMSSSESSPTAINSPISHVRPFLPIPPGVLNPFYSRSLLHHINSNEFKLHNDGYRNQYSNIYSQNSLSYPSLGSDSRIYPPRFSRGMVEELTAYSRSMIGSHPPPPFSSSASHTLGGMTHLDNYSYNRHDQSSTVTDENETTDNIKRNHGTYKKSSSPNVD+NVSHNDDKDSTSEISVCSEDNDQQLVSSSIVNGRVTQSPQLNSVFRKRTLSMSDSNSKL DENTIMQKRCRSMYKAEETIKTEEVCHSIDIIKSEAHSHSYPKSMTNEAEYLSDSLSEIQTSSSNDPSTTNSSTSSRGTSSAPILNSSWNIIP               RYSYQLDPCSEIKLSRSQFDNAMSAKKAVGLDNNNSISHDYYLHHQNQDLRIDSDRLVNRMYCSQESLGYPNGLSTDILKMPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLKMRMSPISPMNSHLSDIKLLSPYSKTCIEDQPCSDSGSASTGIINVDENVSPDNNNNTSTIVSSVTDK
Sbjct:    1 MFTQPVNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIITAPFNVFASTNTGNHHHHSNHSSTHGEINGIIGNTMPQHGSYHLNPNSSIHRLTGSMHNSNSSAHHHNLSTNMGLNFRSTAIGSNVQQNGLGMSSSESSPTAINSPISHVRPFLPIPPGVLNPFYSRSLLHHINSNEFKLHNDGYRNQYSNIYSQNSLSYPSLGSDSRIYPPRFSRGMVEELTAYSRSMIGSHPPPPFSSSASHTLGGMTHLDNYSYNRHDQSSTVTDENETTDNIKRNHGTYKKSSSPNVDINVSHNDDKDSTSEISVCSEDNDQQLVSSSIVNGRVTQSPQLNSVFRKRTLSMSDSNSKLADENTIMQKRCRSMYKAEETIKTEEVCHSIDIIKSEAHSHSYPKSMTNEAEYLSDSLSEIQTSSSNDPSTTNSSTSSRGTSSAPILNSSWNIIP---------------RYSYQLDPCSEIKLSRSQFDNAMSAKKAVGLDNNNSISHDYYLHHQNQDLRIDSDRLVNRMYCSQESLGYPNGLSTDILKMPSLESLLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLKMRMSPISPMNSHLSDIKLLSPYSKTCIEDQPCSDSGSASTGIINVDENVSPDNNNNTSTIVSSVTDK 842

HSP 2 Score: 138.658 bits (348), Expect = 4.953e-33
Identity = 80/80 (100.00%), Postives = 80/80 (100.00%), Query Frame = 3

Query: 2781 TTPISICENLLNTTSIHNEXXXXXXXXXXXXXXGFKMHYESIPSLTHRLARTTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
            TTPISICENLLNTTSIHNESKPKVSPVPDDKDDGFKMHYESIPSLTHRLARTTGLDVDDLWELCILRLSFVKGWGPDYPR
Sbjct:  843 TTPISICENLLNTTSIHNESKPKVSPVPDDKDDGFKMHYESIPSLTHRLARTTGLDVDDLWELCILRLSFVKGWGPDYPR 922

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Planmine SMEST
Match: SMESG000013170.1 (SMESG000013170.1)

HSP 1 Score: 210.305 bits (534), Expect = 1.018e-57
Identity = 92/146 (63.01%), Postives = 117/146 (80.14%), Query Frame = 1

Query: 2140 LESLLRNTSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHL 2577
            L++L      + W TI+YFE++ QVGE FKVP  +  V++DGYTDPSSPNRF LG+L N+HR +S EK+RLYIG+G++L +VG+G++WIRCLS  SVFVQSYYLD +A RQPG AVHKIYPGAYIKVFD+RQC++Q+K A  E  L
Sbjct:  339 LQALTHQRPPEYWCTIAYFELNQQVGELFKVPSQYSCVTVDGYTDPSSPNRFCLGQLSNVHRSESSEKSRLYIGKGVELNNVGEGDVWIRCLSAHSVFVQSYYLDREAGRQPGDAVHKIYPGAYIKVFDIRQCHQQMKKASTEAQL 484

HSP 2 Score: 206.068 bits (523), Expect = 2.963e-56
Identity = 87/134 (64.93%), Postives = 115/134 (85.82%), Query Frame = 1

Query:  244 VNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIITAPFNV 645
            VNS+DAC+SIV SLL  R+ GES+ F+++AIESLVKKLK+KR+ELD LI AV+T+G  PT CVTI +TLDGRLQ+AGRKCFPHVIY+RIWRWP+LHKNEL+  K C+YG+++K + VC+NPYHY+R++ +  ++
Sbjct:    9 VNSNDACMSIVNSLLCHRQGGESQNFSRKAIESLVKKLKEKREELDFLITAVTTSGTQPTGCVTIPKTLDGRLQIAGRKCFPHVIYSRIWRWPNLHKNELRQNKCCIYGYEMKLDYVCINPYHYDRVVPSAVDI 142

HSP 3 Score: 51.9878 bits (123), Expect = 2.082e-6
Identity = 21/29 (72.41%), Postives = 23/29 (79.31%), Query Frame = 3

Query: 2934 TTGLDVDDLWELCILRLSFVKGWGPDYPR 3020
              G+ VDDL   C+LRLSFVKGWGPDYPR
Sbjct:  517 AAGIGVDDLSPFCVLRLSFVKGWGPDYPR 545

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Planmine SMEST
Match: SMESG000056334.1 (SMESG000056334.1)

HSP 1 Score: 132.109 bits (331), Expect = 1.143e-32
Identity = 62/118 (52.54%), Postives = 86/118 (72.88%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E + +A++A++SLVKKLK KR  L++L  A+S      ++CVTIQR+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK  +FC Y F  K++ +C+NPYHY+RI
Sbjct:   20 VKRLLGWKQGDEEDKWAEKAVDSLVKKLKKKRGALESLEKALSNPTEQ-SECVTIQRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLEFCKYPFSAKEKEICINPYHYKRI 136

HSP 2 Score: 94.3597 bits (233), Expect = 4.829e-20
Identity = 51/131 (38.93%), Postives = 81/131 (61.83%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSS-PNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALI 2565
            W+T+ Y+E++++VGE F        + IDG+TDPS+  +RF LG L N++R  ++E  R +IG+G+ L  VG GE++  CLS  S+FVQS   +++    P   V KI PG  +K+F  R+  EQ+   ++
Sbjct:  216 WSTVVYYELNSRVGEAFHA--RLPSIIIDGFTDPSNNADRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVFAECLSDSSIFVQSRNCNYRHNFHP-STVCKIPPGCSLKIFSNREFAEQLSRTVV 342

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Planmine SMEST
Match: SMESG000056334.1 (SMESG000056334.1)

HSP 1 Score: 132.109 bits (331), Expect = 1.153e-32
Identity = 62/118 (52.54%), Postives = 86/118 (72.88%), Query Frame = 1

Query:  274 VQSLLTRRKSGESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLHK-NELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            V+ LL  ++  E + +A++A++SLVKKLK KR  L++L  A+S      ++CVTIQR+LDGRLQV+ RK  PHVIY R+WRWPDL   +ELK  +FC Y F  K++ +C+NPYHY+RI
Sbjct:   20 VKRLLGWKQGDEEDKWAEKAVDSLVKKLKKKRGALESLEKALSNPTEQ-SECVTIQRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLEFCKYPFSAKEKEICINPYHYKRI 136

HSP 2 Score: 93.9745 bits (232), Expect = 5.343e-20
Identity = 51/131 (38.93%), Postives = 81/131 (61.83%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSS-PNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALI 2565
            W+T+ Y+E++++VGE F        + IDG+TDPS+  +RF LG L N++R  ++E  R +IG+G+ L  VG GE++  CLS  S+FVQS   +++    P   V KI PG  +K+F  R+  EQ+   ++
Sbjct:  217 WSTVVYYELNSRVGEAFHA--RLPSIIIDGFTDPSNNADRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVFAECLSDSSIFVQSRNCNYRHNFHP-STVCKIPPGCSLKIFSNREFAEQLSRTVV 343

[Close]

BLAST of Mothers against decapentaplegic homolog vs. Planmine SMEST
Match: SMESG000031386.1 (SMESG000031386.1)

HSP 1 Score: 115.161 bits (287), Expect = 2.044e-26
Identity = 52/107 (48.60%), Postives = 78/107 (72.90%), Query Frame = 1

Query:  307 ESEGFAKRAIESLVKKLKDKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARIWRWPDLH-KNELKHCKFCVYGFDLKQESVCVNPYHYERI 624
            + + + ++A++SLVK+LK K ++++ L  A+    +  TKC+T+QR+LDGRLQVA +K  PH+ Y ++WRWPDLH ++EL+    C Y F LK+E VC+NPYHY RI
Sbjct:   24 KEDKWKEKAVKSLVKRLK-KSNQIEELEKAIRNQ-DSGTKCITLQRSLDGRLQVAQKKGLPHIFYCQLWRWPDLHTQHELRPIDTCEYSFHLKKEEVCINPYHYRRI 128

HSP 2 Score: 86.6557 bits (213), Expect = 2.548e-17
Identity = 54/168 (32.14%), Postives = 88/168 (52.38%), Query Frame = 1

Query: 2176 WTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKLVNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHKAYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLKMRMSPISPMNSHLSDIK-LLSPYSKTCIEDQPC 2676
            W +I Y+E+    GE F    + L  ++DG+TDP+  +RF LG + N++R    E AR +IG+G+ L  +G GE++  CLS  ++FVQS   ++     P   V KI P   +K+FD  Q + Q+ A  +    +   +     +  LS +K   S Y +  + + PC
Sbjct:  315 WCSIRYYELSVAFGETFHCSTSCL--TVDGFTDPAQSDRFCLGLVSNVNRNPQTELARRHIGKGLRLYYIG-GEVFAECLSESAIFVQSPNCNYLNGWHP-ATVCKIPPRCNLKIFD-NQVFAQLLADSVSKGFEAVFTLTHMCSIRLSFVKGWGSDYRRQTVTNTPC 477

The following BLAST results are available for this feature:

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Human
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Celegans
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Fly
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Zebrafish
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Xenopus
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Mouse
BLAST of Mothers against decapentaplegic homolog vs. UniProt/SwissProt
BLAST of Mothers against decapentaplegic homolog vs. TrEMBL
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Cavefish
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Sea Lamprey
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Yeast
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Nematostella
BLAST of Mothers against decapentaplegic homolog vs. Ensembl Medaka
BLAST of Mothers against decapentaplegic homolog vs. Planmine SMEST

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SMAD4	8.892e-58	77.34	SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:...	[more]
SMAD4	4.352e-57	77.95	SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:...	[more]
SMAD4	5.219e-54	77.34	SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:...	[more]
SMAD4	1.675e-53	77.34	SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:...	[more]
SMAD4	1.675e-53	77.34	SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sma-4	1.768e-40	56.92	Dwarfin sma-4 [Source:UniProtKB/Swiss-Prot;Acc:P4...	[more]
sma-4	1.768e-40	56.92	Dwarfin sma-4 [Source:UniProtKB/Swiss-Prot;Acc:P4...	[more]
sma-4	1.768e-40	56.92	Dwarfin sma-4 [Source:UniProtKB/Swiss-Prot;Acc:P4...	[more]
sma-2	1.036e-26	46.09	Dwarfin sma-2 [Source:UniProtKB/Swiss-Prot;Acc:Q0...	[more]
sma-2	1.036e-26	46.09	Dwarfin sma-2 [Source:UniProtKB/Swiss-Prot;Acc:Q0...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Med	4.999e-63	78.91	gene:FBgn0011655 transcript:FBtr0085816	[more]
Med	1.361e-62	78.91	gene:FBgn0011655 transcript:FBtr0085815	[more]
Med	1.361e-62	78.91	gene:FBgn0011655 transcript:FBtr0337030	[more]
Mad	4.375e-33	52.54	gene:FBgn0011648 transcript:FBtr0077616	[more]
Mad	7.534e-33	52.54	gene:FBgn0011648 transcript:FBtr0332372	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-222b8.1	2.555e-61	77.34	si:dkey-222b8.1 [Source:ZFIN;Acc:ZDB-GENE-060503-2...	[more]
si:dkey-222b8.1	2.555e-61	77.34	si:dkey-222b8.1 [Source:ZFIN;Acc:ZDB-GENE-060503-2...	[more]
smad4b	7.345e-55	73.33	SMAD family member 4b [Source:ZFIN;Acc:ZDB-GENE-06...	[more]
si:dkey-222b8.1	1.384e-54	78.13	si:dkey-222b8.1 [Source:ZFIN;Acc:ZDB-GENE-060503-2...	[more]
smad4a	3.438e-53	76.56	SMAD family member 4a [Source:ZFIN;Acc:ZDB-GENE-99...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
acsl6	6.941e-55	77.34	acyl-CoA synthetase long chain family member 6 [So...	[more]
acsl6	5.000e-54	77.34	acyl-CoA synthetase long chain family member 6 [So...	[more]
acsl6	8.424e-54	77.34	acyl-CoA synthetase long chain family member 6 [So...	[more]
acsl6	9.992e-54	77.34	acyl-CoA synthetase long chain family member 6 [So...	[more]
acsl6	1.380e-53	77.34	acyl-CoA synthetase long chain family member 6 [So...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Smad4	1.241e-53	77.34	SMAD family member 4 [Source:MGI Symbol;Acc:MGI:89...	[more]
Smad4	1.241e-53	77.34	SMAD family member 4 [Source:MGI Symbol;Acc:MGI:89...	[more]
Smad9	1.082e-28	53.33	SMAD family member 9 [Source:MGI Symbol;Acc:MGI:18...	[more]
Smad5	3.371e-28	51.69	SMAD family member 5 [Source:MGI Symbol;Acc:MGI:13...	[more]
Smad5	3.371e-28	51.69	SMAD family member 5 [Source:MGI Symbol;Acc:MGI:13...	[more]

BLAST of Mothers against decapentaplegic homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q13485\|SMAD4_HUMAN	8.044e-53	77.34	Mothers against decapentaplegic homolog 4 OS=Homo ...	[more]
sp\|P97471\|SMAD4_MOUSE	8.680e-53	77.34	Mothers against decapentaplegic homolog 4 OS=Mus m...	[more]
sp\|Q1HE26\|SMAD4_BOVIN	9.019e-53	77.34	Mothers against decapentaplegic homolog 4 OS=Bos t...	[more]
sp\|O70437\|SMAD4_RAT	9.548e-53	77.34	Mothers against decapentaplegic homolog 4 OS=Rattu...	[more]
sp\|Q9GKQ9\|SMAD4_PIG	9.732e-53	77.34	Mothers against decapentaplegic homolog 4 OS=Sus s...	[more]

BLAST of Mothers against decapentaplegic homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3JD31	2.929e-66	80.47	mothers against decapentaplegic homolog 4-like OS=...	[more]
A0A0L8GJZ2	9.059e-66	80.47	MH1 domain-containing protein (Fragment) OS=Octopu...	[more]
A0A433SJV6	4.626e-65	78.91	MH1 domain-containing protein (Fragment) OS=Elysia...	[more]
A0A1Y1M7Z1	5.730e-65	73.94	MH1 domain-containing protein OS=Photinus pyralis ...	[more]
W8C7B7	1.062e-64	71.33	Mothers against decapentaplegic-4 OS=Ceratitis cap...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000041590.1	3.143e-58	78.13	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
smad4b	2.642e-57	75.94	SMAD family member 4b [Source:ZFIN;Acc:ZDB-GENE-06...	[more]
si:dkey-222b8.1	7.103e-55	78.13	si:dkey-222b8.1 [Source:ZFIN;Acc:ZDB-GENE-060503-2...	[more]
si:dkey-222b8.1	1.942e-54	78.13	mothers against decapentaplegic homolog 4-like [So...	[more]
si:dkey-222b8.1	2.325e-54	78.13	mothers against decapentaplegic homolog 4-like [So...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000010406.1	2.261e-63	78.91	pep scaffold:Pmarinus_7.0:GL476769:63937:79511:-1 ...	[more]
smad4a	3.247e-58	78.13	SMAD family member 4a [Source:ZFIN;Acc:ZDB-GENE-99...	[more]
smad9	7.077e-30	54.24	SMAD family member 9 [Source:ZFIN;Acc:ZDB-GENE-031...	[more]
ENSPMAT00000010514.1	3.577e-26	65.22	pep scaffold:Pmarinus_7.0:GL482855:12566:14836:-1 ...	[more]
SMAD3	1.578e-24	47.58	SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO31382	2.689e-55	76.56	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37590	4.797e-53	71.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37591	4.582e-46	61.47	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47037	9.937e-30	55.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39594	7.620e-24	44.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000027726.1	5.379e-55	75.94	mothers against decapentaplegic homolog 4 [Source:...	[more]
smad4b	7.738e-54	76.56	mothers against decapentaplegic homolog 4 [Source:...	[more]
smad4b	2.101e-53	76.56	mothers against decapentaplegic homolog 4 [Source:...	[more]
smad4b	2.642e-53	76.56	mothers against decapentaplegic homolog 4 [Source:...	[more]
smad4b	3.437e-53	76.56	mothers against decapentaplegic homolog 4 [Source:...	[more]

BLAST of Mothers against decapentaplegic homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000029614.1	4.953e-33	98.02	SMESG000029614.1	[more]
SMESG000013170.1	1.018e-57	63.01	SMESG000013170.1	[more]
SMESG000056334.1	1.143e-32	52.54	SMESG000056334.1	[more]
SMESG000056334.1	1.153e-32	52.54	SMESG000056334.1	[more]
SMESG000031386.1	2.044e-26	48.60	SMESG000031386.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030074 ID=SMED30030074|Name=Mothers against decapentaplegic homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=3021bp
GATCGATAAAACGATACTATTGCTCATTCGTACTCAATGCATTTTGCTTC
GCATTATTGTATGACCTTGATAAACGATTGTTATTGGCCGGTTAAAAAAA
AGATTTTCCTTTAGAAATTAATTTTATCTAATATTTTGATACATTGACGA
AACAATATTTTTCCACCAAAATGTCAAAGATAAATAACCAAATATTGTAA
TCAATTTACCATGTTCACCCAACCAGTTAATTCGTATCCACTCGTCAACT
CTTCCGATGCTTGCCTCTCTATTGTTCAAAGTTTACTTACCAGAAGAAAG
AGCGGCGAAAGTGAAGGATTTGCTAAACGAGCCATTGAAAGTCTTGTGAA
AAAGCTGAAAGACAAACGGGATGAATTGGATGCTTTGATCGTCGCTGTAT
CAACAGCTGGGAATCATCCTACAAAGTGCGTTACAATACAGAGAACACTC
GATGGTCGTTTGCAAGTGGCCGGTCGGAAATGCTTTCCACATGTGATATA
CGCTCGAATTTGGCGCTGGCCAGATCTCCACAAAAACGAACTGAAACATT
GTAAATTCTGCGTTTACGGATTCGATTTGAAACAGGAATCGGTCTGCGTC
AACCCATACCACTATGAAAGAATTATCACTGCTCCGTTCAACGTGTTCGC
GTCGACCAATACTGGGAATCATCACCATCATTCCAACCACAGTTCAACTC
ACGGGGAAATTAACGGGATAATTGGAAATACGATGCCACAACATGGATCA
TATCATTTAAATCCCAATTCATCGATTCACAGACTTACCGGATCAATGCA
TAACTCCAATAGTTCAGCACATCATCACAATTTGTCTACAAATATGGGCT
TGAATTTCCGGAGCACAGCGATTGGTTCAAATGTTCAGCAGAACGGACTC
GGTATGTCATCTTCCGAATCATCTCCCACTGCCATCAATTCTCCCATATC
TCACGTCAGACCGTTTTTACCGATTCCACCTGGAGTTCTGAATCCCTTTT
ATTCTAGATCATTGTTACACCATATCAATTCCAATGAATTCAAGTTACAC
AATGATGGATACAGAAATCAGTACTCAAATATTTATTCTCAAAATTCTCT
TTCATATCCATCTTTGGGGTCCGATTCGAGAATTTATCCGCCGAGATTTT
CAAGGGGAATGGTAGAAGAATTAACTGCTTATAGTCGATCTATGATTGGA
TCTCATCCGCCACCTCCGTTTTCATCCTCCGCTTCACATACATTAGGTGG
AATGACACATTTGGATAACTATTCTTATAATCGGCATGATCAATCTTCCA
CAGTAACCGATGAAAATGAAACTACTGACAACATTAAACGAAATCATGGA
ACTTATAAAAAGTCATCTTCACCAAATGTTGATTTAAATGTCTCTCACAA
TGATGATAAAGACTCAACTAGCGAAATCAGCGTATGTAGTGAAGACAATG
ATCAACAGTTGGTTTCATCCTCCATTGTCAATGGTCGAGTTACCCAGTCC
CCCCAATTGAATAGCGTATTTAGAAAGCGAACGTTATCTATGTCGGATAG
TAACTCTAAATTGGTAGACGAAAACACCATAATGCAAAAACGATGCCGAT
CCATGTACAAAGCGGAAGAAACCATCAAAACGGAAGAAGTATGCCATTCA
ATAGATATAATAAAATCCGAAGCTCACTCTCATTCATATCCCAAGTCTAT
GACGAACGAGGCGGAATATCTAAGCGATTCTTTATCAGAAATACAAACCT
CTTCATCAAATGATCCATCAACAACAAACAGTTCGACATCTTCGAGAGGA
ACTTCATCGGCTCCGATACTTAATTCTTCGTGGAATATCATACCCAGGTT
ACAATCAGTCGATAAAGATCTTCATATCGACATTAATTCAAGATATTCTT
ATCAGTTAGATCCATGCAGCGAGATCAAGTTGAGCCGTTCACAATTTGAC
AACGCCATGAGTGCCAAGAAAGCTGTGGGATTGGATAATAATAATTCTAT
TAGTCATGATTATTATTTGCACCATCAGAACCAAGATTTACGAATAGATT
CAGATCGCTTGGTAAATAGGATGTACTGCAGCCAGGAAAGTTTAGGATAT
CCAAATGGTTTATCAACAGATATTTTAAAAATGCCATCCCTTGAATCTCT
TTTAAGAAATACCTCAACTGATATTTGGACAACAATCTCATATTTTGAAA
TGGATACACAAGTAGGAGAATGCTTCAAAGTACCAGTGAACTTTCTCAAA
GTTTCAATTGATGGATATACAGACCCTTCATCGCCGAATAGATTTAGTTT
AGGAAAACTTGTCAATATCCACAGAGTGGATTCTGTTGAAAAAGCTCGAT
TATATATTGGTAGAGGAATCGACCTTGAAAGTGTTGGGGACGGAGAAATT
TGGATACGTTGTCTTTCTGGTTTTTCGGTATTCGTACAAAGTTATTATCT
TGATCATAAAGCATATAGACAGCCAGGCGGAGCCGTGCACAAAATATATC
CTGGTGCATATATAAAAGTATTTGATGTTCGTCAGTGTTACGAGCAAATT
AAAGCTGCTCTAATAGAGCACCATTTAAAGATGAGAATGAGTCCTATCTC
ACCAATGAATAGTCATTTGTCGGATATCAAGCTGTTAAGTCCTTATTCAA
AGACCTGCATCGAGGATCAACCTTGCAGCGATTCCGGAAGTGCATCGACT
GGAATTATAAATGTAGATGAGAATGTTTCACCGGACAATAATAACAACAC
CAGTACAATAGTTTCAAGTGTTACGGATAAACCACTCCAATATCTATTTG
TGAAAATCTTTTGAATACAACTTCTATTCATAACGAAAGCAAGCCGAAAG
TAAGTCCGGTTCCAGATGACAAAGACGACGGCTTCAAAATGCATTATGAG
TCTATACCAAGTCTAACACACAGATTGGCTAGAACTACTGGACTTGATGT
TGATGATCTTTGGGAACTATGCATACTCAGATTAAGTTTTGTTAAAGGTT
GGGGGCCTGATTATCCCCGTG

protein sequence of SMED30030074-orf-1

>SMED30030074-orf-1 ID=SMED30030074-orf-1|Name=SMED30030074-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=868bp
MFTQPVNSYPLVNSSDACLSIVQSLLTRRKSGESEGFAKRAIESLVKKLK
DKRDELDALIVAVSTAGNHPTKCVTIQRTLDGRLQVAGRKCFPHVIYARI
WRWPDLHKNELKHCKFCVYGFDLKQESVCVNPYHYERIITAPFNVFASTN
TGNHHHHSNHSSTHGEINGIIGNTMPQHGSYHLNPNSSIHRLTGSMHNSN
SSAHHHNLSTNMGLNFRSTAIGSNVQQNGLGMSSSESSPTAINSPISHVR
PFLPIPPGVLNPFYSRSLLHHINSNEFKLHNDGYRNQYSNIYSQNSLSYP
SLGSDSRIYPPRFSRGMVEELTAYSRSMIGSHPPPPFSSSASHTLGGMTH
LDNYSYNRHDQSSTVTDENETTDNIKRNHGTYKKSSSPNVDLNVSHNDDK
DSTSEISVCSEDNDQQLVSSSIVNGRVTQSPQLNSVFRKRTLSMSDSNSK
LVDENTIMQKRCRSMYKAEETIKTEEVCHSIDIIKSEAHSHSYPKSMTNE
AEYLSDSLSEIQTSSSNDPSTTNSSTSSRGTSSAPILNSSWNIIPRLQSV
DKDLHIDINSRYSYQLDPCSEIKLSRSQFDNAMSAKKAVGLDNNNSISHD
YYLHHQNQDLRIDSDRLVNRMYCSQESLGYPNGLSTDILKMPSLESLLRN
TSTDIWTTISYFEMDTQVGECFKVPVNFLKVSIDGYTDPSSPNRFSLGKL
VNIHRVDSVEKARLYIGRGIDLESVGDGEIWIRCLSGFSVFVQSYYLDHK
AYRQPGGAVHKIYPGAYIKVFDVRQCYEQIKAALIEHHLKMRMSPISPMN
SHLSDIKLLSPYSKTCIEDQPCSDSGSASTGIINVDENVSPDNNNNTSTI
VSSVTDKPLQYLFVKIF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000044	cephalic ganglia
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR036578	SMAD_MH1_sf
IPR013790	Dwarfin
IPR001132	SMAD_dom_Dwarfin-type
IPR003619	MAD_homology1_Dwarfin-type
IPR013019	MAD_homology_MH1
IPR017855	SMAD-like_dom_sf
IPR008984	SMAD_FHA_dom_sf

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular
GO:0005667	transcription factor complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043234	protein complex

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0006351	transcription, DNA-templated
GO:0042177	negative regulation of protein catabolic process

Vocabulary: **molecular function**
Term	Definition
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0005515	protein binding
GO:0003677	DNA binding
GO:0031005	filamin binding
GO:0046332	SMAD binding
GO:0046872	metal ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 39..62
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 501..533
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 359..403
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 363..380
None	No IPR available	PANTHER	PTHR13703:SF45	MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 4	coord: 13..224
None	No IPR available	PANTHER	PTHR13703:SF45	MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 4	coord: 372..782
None	No IPR available	CDD	cd10492	MH1_SMAD_4	coord: 16..139 e-value: 7.57432E-79 score: 248.907
IPR001132	SMAD domain, Dwarfin-type	SMART	SM00524	dwBultra2	coord: 654..804 e-value: 3.3E-36 score: 136.3
IPR001132	SMAD domain, Dwarfin-type	PFAM	PF03166	MH2	coord: 655..799 e-value: 6.9E-40 score: 137.2
IPR001132	SMAD domain, Dwarfin-type	PROSITE	PS51076	MH2	coord: 656..855 score: 36.088
IPR003619	MAD homology 1, Dwarfin-type	SMART	SM00523	dwAneu5	coord: 33..142 e-value: 4.0E-54 score: 195.8
IPR003619	MAD homology 1, Dwarfin-type	PFAM	PF03165	MH1	coord: 39..138 e-value: 4.2E-36 score: 123.3
IPR017855	SMAD-like domain superfamily	GENE3D	G3DSA:2.60.200.10		coord: 649..824 e-value: 2.5E-52 score: 179.9
IPR036578	SMAD MH1 domain superfamily	GENE3D	G3DSA:3.90.520.10		coord: 12..141 e-value: 5.5E-56 score: 189.8
IPR036578	SMAD MH1 domain superfamily	SUPERFAMILY	SSF56366	SMAD MH1 domain	coord: 25..139
IPR013790	Dwarfin	PANTHER	PTHR13703	SMAD	coord: 13..224
IPR013790	Dwarfin	PANTHER	PTHR13703	SMAD	coord: 372..782
IPR013019	MAD homology, MH1	PROSITE	PS51075	MH1	coord: 20..144 score: 32.817
IPR008984	SMAD/FHA domain superfamily	SUPERFAMILY	SSF49879	SMAD/FHA domain	coord: 629..788

Main menu

Mothers against decapentaplegic homolog

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Owlery

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