Argininosuccinate lyase

Overview


Name	Argininosuccinate lyase
Smed ID	SMED30030034
Length (bp)	1597

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Argininosuccinate lyase (SMED30030034) t-SNE clustered cells

Violin plots show distribution of expression levels for Argininosuccinate lyase (SMED30030034) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Argininosuccinate lyase (SMED30030034) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Argininosuccinate lyase (SMED30030034) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030034

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pigment cell	SMED30030034	SMESG000039074.1	SmedASXL_005315	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
X2 cell	SMED30030034	SMESG000039074.1	SmedASXL_005315	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
epidermis	SMED30030034	SMESG000039074.1	dd_Smed_v4_3792_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30030034	SMESG000039074.1	dd_Smed_v4_3792_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30030034	SMESG000039074.1	dd_Smed_v4_3792_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30030034	SMESG000039074.1	dd_Smed_v4_3792_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30030034	SMESG000039074.1	Contig39428	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30030034	SMESG000039074.1	Contig39428	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Category 3 cell	SMED30030034	SMESG000039074.1	dd_Smed_v6_3792_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Argininosuccinate lyase vs. Ensembl Human
Match: ASL (argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746])

HSP 1 Score: 561.222 bits (1445), Expect = 0.000e+0
Identity = 258/448 (57.59%), Postives = 338/448 (75.45%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FNASI +D+ LW  D+ GSKAY+  + K  LLT  E ++++ GLD++ EEW    F LN  DEDIHTANERRLKELIG T GKLHTGRSRNDQV TD RLW RQ        +   I+ +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM++++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV+ +W+Y +SVEQY  LGGT+  SV++QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQV 455

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Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FNASI +D+ LW  D+ GSKAY+  + K  LLT  E ++++ GLD++ EEW    F LN  DEDIHTANERRLKELIG T GKLHTGRSRNDQV TD RLW RQ        +   I+ +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM++++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV+ +W+Y +SVEQY  LGGT+  SV++QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQV 455

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BLAST of Argininosuccinate lyase vs. Ensembl Human
Match: ASL (argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746])

HSP 1 Score: 523.087 bits (1346), Expect = 0.000e+0
Identity = 245/448 (54.69%), Postives = 324/448 (72.32%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FNASI +D+ LW  D+ GSKAY+  + K  LLT  E ++++ GLD++ EEW    F LN  DEDIHTANERRLKELIG T GKLHTGRSRNDQV TD RLW RQ        +   I+ +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G                    +EDKE++F++ DTM++++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV+ +W+Y +SVEQY  LGGT+  SV++QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFG--------------------REDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQV 435

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BLAST of Argininosuccinate lyase vs. Ensembl Human
Match: ASL (argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746])

HSP 1 Score: 520.005 bits (1338), Expect = 0.000e+0
Identity = 246/448 (54.91%), Postives = 320/448 (71.43%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FNASI +D+ LW  D+ GSKAY+  + K  LLT  E ++++ GLD++ EEW    F LN  DEDIHTANERRLKELIG T GKLHTGRSRNDQV TD RLW RQ        +   I+ +  RA +E ++L PGYTHLQ+AQPIRWSHW++S                          GA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM++++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV+ +W+Y +SVEQY  LGGT+  SV++QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILS--------------------------GAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQV 429

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Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FNASI +D+ LW  D+ GSKAY+  + K  LLT  E ++++ GLD++ EEW    F LN  DEDIHTANERRLKELIG T GKLHTGRSRNDQV TD RLW RQ        +   I+ +  RA +E ++L PGYTHLQ+AQPIRWSHW++S                          GA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM++++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV+ +W+Y +SVEQY  LGGT+  SV++QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILS--------------------------GAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQV 429

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BLAST of Argininosuccinate lyase vs. Ensembl Celegans
Match: fum-1 (Probable fumarate hydratase, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:O17214])

HSP 1 Score: 48.9062 bits (115), Expect = 5.061e-6
Identity = 45/214 (21.03%), Postives = 84/214 (39.25%), Query Frame = 2

Query:  425 RSRNDQVATDTRLWC-RQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSM---------NSLDGVSSRDYIVELQSCATICAINLSRLAEDL-IIYSTKEFSFVRIS-DAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAI 1030
            +S ND   T   +   R+   + L  +K     +  +A    +I+  G TH Q A P+       +Y + L    +R    + R+    L +G  A       RK  A+++  T   +         N  + +++ D +VE+       A++  ++  D+  + S        +S      GSS+MP K NP   E I     ++ G  +  ++
Sbjct:    3 QSSNDTFPTAMHIAVGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNSIARVESTLPRL--YQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPNKFEALAAHDALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAITMVAAQVMGNQVAVSV 214

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Query:  425 RSRNDQVATDTRLWC-RQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSM---------NSLDGVSSRDYIVELQSCATICAINLSRLAEDL-IIYSTKEFSFVRIS-DAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAI 1030
            +S ND   T   +   R+   + L  +K     +  +A    +I+  G TH Q A P+       +Y + L    +R    + R+    L +G  A       RK  A+++  T   +         N  + +++ D +VE+       A++  ++  D+  + S        +S      GSS+MP K NP   E I     ++ G  +  ++
Sbjct:    3 QSSNDTFPTAMHIAVGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNSIARVESTLPRL--YQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPNKFEALAAHDALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAITMVAAQVMGNQVAVSV 214

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Query:  425 RSRNDQVATDTRLWC-RQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSM---------NSLDGVSSRDYIVELQSCATICAINLSRLAEDL-IIYSTKEFSFVRIS-DAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAI 1030
            +S ND   T   +   R+   + L  +K     +  +A    +I+  G TH Q A P+       +Y + L    +R    + R+    L +G  A       RK  A+++  T   +         N  + +++ D +VE+       A++  ++  D+  + S        +S      GSS+MP K NP   E I     ++ G  +  ++
Sbjct:    3 QSSNDTFPTAMHIAVGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNSIARVESTLPRL--YQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPNKFEALAAHDALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAITMVAAQVMGNQVAVSV 214

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Query:  425 RSRNDQVATDTRLWC-RQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSM---------NSLDGVSSRDYIVELQSCATICAINLSRLAEDL-IIYSTKEFSFVRIS-DAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAI 1030
            +S ND   T   +   R+   + L  +K     +  +A    +I+  G TH Q A P+       +Y + L    +R    + R+    L +G  A       RK  A+++  T   +         N  + +++ D +VE+       A++  ++  D+  + S        +S      GSS+MP K NP   E I     ++ G  +  ++
Sbjct:    3 QSSNDTFPTAMHIAVGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNSIARVESTLPRL--YQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPNKFEALAAHDALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAITMVAAQVMGNQVAVSV 214

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Query:  425 RSRNDQVATDTRLWC-RQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSM---------NSLDGVSSRDYIVELQSCATICAINLSRLAEDL-IIYSTKEFSFVRIS-DAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAI 1030
            +S ND   T   +   R+   + L  +K     +  +A    +I+  G TH Q A P+       +Y + L    +R    + R+    L +G  A       RK  A+++  T   +         N  + +++ D +VE+       A++  ++  D+  + S        +S      GSS+MP K NP   E I     ++ G  +  ++
Sbjct:    3 QSSNDTFPTAMHIAVGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNSIARVESTLPRL--YQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPNKFEALAAHDALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAITMVAAQVMGNQVAVSV 214

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BLAST of Argininosuccinate lyase vs. Ensembl Fly
Match: Argl (gene:FBgn0032076 transcript:FBtr0100481)

HSP 1 Score: 445.662 bits (1145), Expect = 1.023e-152
Identity = 210/452 (46.46%), Postives = 305/452 (67.48%), Query Frame = 2

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLK 1465
            + +WGGRF+      + + N S+ +D RL+ +D+D SKAYA A+++  L+   E +K++  L+ ++ +W      +   DED+HT NER L E+ G  G +LHTGRSRNDQV TD +LW R+ + + L  +   I+    +A   + +LMPGYTHLQ+AQ +++SHWL+S+A +L+ D  R  +L  R ++ PLGSGALAGNP  IDR  LA+ L F+ V+ NS+  V  RD++V+   C ++ +++LSRLAEDLIIYSTKEF F++++D +S+GSSLMPQK+NPDSLELIRG  G I   + G  +T+KGTPSTYNKD Q DK+  F   D ++ ++++  GVL T++V +     ALS DMLATD AYYLV+KGVPFR AH I G+ V+ +EK G  I+ L LG L     LF  D++ + +Y N+V+QY+ +GGT+  S+  Q++ + K
Sbjct:    9 YKMWGGRFTEGPHEALHSLNNSLPYDSRLYADDLDASKAYAEALHRAGLINSAEADKLVKNLELLRFDWIEGTVKILPGDEDVHTVNERLLVEITGELGQRLHTGRSRNDQVVTDMKLWLRKAIRETLGRLSGIIETATRQAELHLGVLMPGYTHLQRAQTVQFSHWLLSHAFALREDGQRLLELRDRANVLPLGSGALAGNPLGIDRLWLAERLGFSGVTANSMHAVGDRDFVVDFIYCCSMVSLHLSRLAEDLIIYSTKEFDFIKLADGFSSGSSLMPQKRNPDSLELIRGMAGVITANLTGIMMTIKGTPSTYNKDLQYDKQFCFQSFDKLSQVLEVTDGVLQTIQVKQESMEAALSTDMLATDWAYYLVKKGVPFRQAHHIIGRVVSEAEKRGVDITDLPLGDLQKFSPLFGSDIVAVADYSNNVQQYNAIGGTASSSIVEQLRLLKK 460

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BLAST of Argininosuccinate lyase vs. Ensembl Fly
Match: Argl (gene:FBgn0032076 transcript:FBtr0299780)

HSP 1 Score: 445.662 bits (1145), Expect = 1.023e-152
Identity = 210/452 (46.46%), Postives = 305/452 (67.48%), Query Frame = 2

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLK 1465
            + +WGGRF+      + + N S+ +D RL+ +D+D SKAYA A+++  L+   E +K++  L+ ++ +W      +   DED+HT NER L E+ G  G +LHTGRSRNDQV TD +LW R+ + + L  +   I+    +A   + +LMPGYTHLQ+AQ +++SHWL+S+A +L+ D  R  +L  R ++ PLGSGALAGNP  IDR  LA+ L F+ V+ NS+  V  RD++V+   C ++ +++LSRLAEDLIIYSTKEF F++++D +S+GSSLMPQK+NPDSLELIRG  G I   + G  +T+KGTPSTYNKD Q DK+  F   D ++ ++++  GVL T++V +     ALS DMLATD AYYLV+KGVPFR AH I G+ V+ +EK G  I+ L LG L     LF  D++ + +Y N+V+QY+ +GGT+  S+  Q++ + K
Sbjct:    9 YKMWGGRFTEGPHEALHSLNNSLPYDSRLYADDLDASKAYAEALHRAGLINSAEADKLVKNLELLRFDWIEGTVKILPGDEDVHTVNERLLVEITGELGQRLHTGRSRNDQVVTDMKLWLRKAIRETLGRLSGIIETATRQAELHLGVLMPGYTHLQRAQTVQFSHWLLSHAFALREDGQRLLELRDRANVLPLGSGALAGNPLGIDRLWLAERLGFSGVTANSMHAVGDRDFVVDFIYCCSMVSLHLSRLAEDLIIYSTKEFDFIKLADGFSSGSSLMPQKRNPDSLELIRGMAGVITANLTGIMMTIKGTPSTYNKDLQYDKQFCFQSFDKLSQVLEVTDGVLQTIQVKQESMEAALSTDMLATDWAYYLVKKGVPFRQAHHIIGRVVSEAEKRGVDITDLPLGDLQKFSPLFGSDIVAVADYSNNVQQYNAIGGTASSSIVEQLRLLKK 460

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Fly
Match: Argl (gene:FBgn0032076 transcript:FBtr0340263)

HSP 1 Score: 445.662 bits (1145), Expect = 1.023e-152
Identity = 210/452 (46.46%), Postives = 305/452 (67.48%), Query Frame = 2

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLK 1465
            + +WGGRF+      + + N S+ +D RL+ +D+D SKAYA A+++  L+   E +K++  L+ ++ +W      +   DED+HT NER L E+ G  G +LHTGRSRNDQV TD +LW R+ + + L  +   I+    +A   + +LMPGYTHLQ+AQ +++SHWL+S+A +L+ D  R  +L  R ++ PLGSGALAGNP  IDR  LA+ L F+ V+ NS+  V  RD++V+   C ++ +++LSRLAEDLIIYSTKEF F++++D +S+GSSLMPQK+NPDSLELIRG  G I   + G  +T+KGTPSTYNKD Q DK+  F   D ++ ++++  GVL T++V +     ALS DMLATD AYYLV+KGVPFR AH I G+ V+ +EK G  I+ L LG L     LF  D++ + +Y N+V+QY+ +GGT+  S+  Q++ + K
Sbjct:    9 YKMWGGRFTEGPHEALHSLNNSLPYDSRLYADDLDASKAYAEALHRAGLINSAEADKLVKNLELLRFDWIEGTVKILPGDEDVHTVNERLLVEITGELGQRLHTGRSRNDQVVTDMKLWLRKAIRETLGRLSGIIETATRQAELHLGVLMPGYTHLQRAQTVQFSHWLLSHAFALREDGQRLLELRDRANVLPLGSGALAGNPLGIDRLWLAERLGFSGVTANSMHAVGDRDFVVDFIYCCSMVSLHLSRLAEDLIIYSTKEFDFIKLADGFSSGSSLMPQKRNPDSLELIRGMAGVITANLTGIMMTIKGTPSTYNKDLQYDKQFCFQSFDKLSQVLEVTDGVLQTIQVKQESMEAALSTDMLATDWAYYLVKKGVPFRQAHHIIGRVVSEAEKRGVDITDLPLGDLQKFSPLFGSDIVAVADYSNNVQQYNAIGGTASSSIVEQLRLLKK 460

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BLAST of Argininosuccinate lyase vs. Ensembl Fly
Match: Fum4 (gene:FBgn0051874 transcript:FBtr0079964)

HSP 1 Score: 55.0694 bits (131), Expect = 1.025e-7
Identity = 55/238 (23.11%), Postives = 102/238 (42.86%), Query Frame = 2

Query:  383 KELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFL-EDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKS--------LAKELNFTDV--SMNSLDGVSSRDYIVELQSCATICAINLSRLAEDL-IIYSTKEFSFVRIS-DAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTY 1057
            KE + P    ++  +S +D  +T  R+     + + L   ++  I ++  ++N  M+++  G THL  A P+        Y   L    +R    M R+   P+G  ++     K+D K+           EL F     S N  + +S+ D +VEL       A ++ ++A D+  + S     F  +       GSS+MP K NP   E +   C ++ G  +  A+++ G+   +
Sbjct:  147 KEPVDPNE-HVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLIKIGRTHLMDAVPLSLGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVG---TKVDTKAEYSAQCIKRIAELTFLPFVESPNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLPENEPGSSIMPGKVNPTQCEAMSMICAQVMGNHV--AVSMGGSSGHF 378

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BLAST of Argininosuccinate lyase vs. Ensembl Fly
Match: Fum1 (gene:FBgn0286222 transcript:FBtr0070954)

HSP 1 Score: 51.2174 bits (121), Expect = 1.887e-6
Identity = 56/221 (25.34%), Postives = 90/221 (40.72%), Query Frame = 2

Query:  425 RSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVI--ATRANSE--MEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDR----KSLAKELNFTDVSM----NSLDGVSSRDYIVELQSCATICAINLSRLAEDL-IIYSTKEFSFVRIS-DAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGT 1045
            +S ND   T   +      L+   ++K  IK +  A RA SE   +I+  G TH   A P+        YA  L     R    + R+    LG G   G      +    K  AK    T +      N  + +++RD +VE+       A++L ++A D+  + S        +S      GSS+MP K NP   E +     ++ G  +  A+T+ G+
Sbjct:  142 QSSNDTFPTAIHISV---ALELNNNLKPAIKTLHDALRAKSEEFKDIIKIGRTHTMDAVPLTLGQEFSGYAQQLAYAQERIDACLPRVYELALG-GTAVGTGLNTRKGFAEKCAAKIAELTSLPFVTAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCESLTMLSAQVMGNQV--AVTIGGS 356

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BLAST of Argininosuccinate lyase vs. Ensembl Zebrafish
Match: asl (argininosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-040426-1152])

HSP 1 Score: 552.747 bits (1423), Expect = 0.000e+0
Identity = 255/454 (56.17%), Postives = 336/454 (74.01%), Query Frame = 2

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            + LWGGRF G  DPIME FNASI +D+R+W+ DI GSKAY  A+ K +L+T  E  +++ GLD++ +EW   +F +   DEDIHTANERRLKELIG   GKLHTGRSRNDQVATD RLW R  +    E     I  +  RA +E+EIL PGYTH+Q+AQPIRWSHWL+S+  ++ RD  R  D+ KR+++ PLGSGA+AGNPF IDR+ L +EL+F  +S+NS+D    RD++ E     ++C  +LS++AEDLI+YSTKEFSF+ ++DAYSTGSSLMPQKKN DSLELIR K GR+ G+  GF +TLKG PSTYNKD QEDKE++FD  DT+ +++++ATGV++TL+V++ K  +ALSPDMLATD+AY+LVRKG+PFR+AHG +GK V ++E     +S LT+  L ++  LF+ DV  +W+Y  SVEQYS  GGTS  SV  QI+    W+
Sbjct:    7 NKLWGGRFVGNTDPIMEKFNASISYDQRMWKADIKGSKAYVKALQKASLVTQNEMEQILTGLDKVLDEWSKGEFEIKPGDEDIHTANERRLKELIGDAAGKLHTGRSRNDQVATDMRLWLRDGIATLKELALQLINTMVERAAAEIEILCPGYTHMQRAQPIRWSHWLLSHVVAISRDVERLEDIRKRVNVMPLGSGAIAGNPFDIDRELLRQELSFDSISINSMDATGQRDFVAEFLFWGSMCLTHLSKMAEDLILYSTKEFSFINLTDAYSTGSSLMPQKKNADSLELIRSKAGRVFGRCAGFLMTLKGLPSTYNKDLQEDKEAMFDTYDTVHAVLQVATGVISTLKVNQVKMEEALSPDMLATDLAYHLVRKGMPFREAHGCAGKAVYIAESKNIRLSQLTVEDLQTVSSLFDKDVSSVWDYVKSVEQYSAPGGTSKSSVTAQIQHFKTWL 460

[Close]

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            + LWGGRF G  DPIME FNASI +D+R+W+ DI GSKAY  A+ K +L+T  E  +++ GLD++ +EW   +F +   DEDIHTANERRLKELIG   GKLHTGRSRNDQVATD RLW R  +    E     I  +  RA +E+EIL PGYTH+Q+AQPIRWSHWL+S+  ++ RD  R  D+ KR+++ PLGSGA+AGNPF IDR+ L +EL+F  +S+NS+D    RD++ E     ++C  +LS++AEDLI+YSTKEFSF+ ++DAYSTGSSLMPQKKN DSLELIR K GR+ G+  GF +TLKG PSTYNKD QEDKE++FD  DT+ +++++ATGV++TL+V++ K  +ALSPDMLATD+AY+LVRKG+PFR+AHG +GK V ++E     +S LT+  L ++  LF+ DV  +W+Y  SVEQYS  GGTS  SV  QI+    W+
Sbjct:    7 NKLWGGRFVGNTDPIMEKFNASISYDQRMWKADIKGSKAYVKALQKASLVTQNEMEQILTGLDKVLDEWSKGEFEIKPGDEDIHTANERRLKELIGDAAGKLHTGRSRNDQVATDMRLWLRDGIATLKELALQLINTMVERAAAEIEILCPGYTHMQRAQPIRWSHWLLSHVVAISRDVERLEDIRKRVNVMPLGSGAIAGNPFDIDRELLRQELSFDSISINSMDATGQRDFVAEFLFWGSMCLTHLSKMAEDLILYSTKEFSFINLTDAYSTGSSLMPQKKNADSLELIRSKAGRVFGRCAGFLMTLKGLPSTYNKDLQEDKEAMFDTYDTVHAVLQVATGVISTLKVNQVKMEEALSPDMLATDLAYHLVRKGMPFREAHGCAGKAVYIAESKNIRLSQLTVEDLQTVSSLFDKDVSSVWDYVKSVEQYSAPGGTSKSSVTAQIQHFKTWL 460

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Zebrafish
Match: asl (argininosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-040426-1152])

HSP 1 Score: 289.656 bits (740), Expect = 6.874e-95
Identity = 130/234 (55.56%), Postives = 169/234 (72.22%), Query Frame = 2

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYI 811
            + LWGGRF G  DPIME FNASI +D+R+W+ DI GSKAY  A+ K +L+T  E  +++ GLD++ +EW   +F +   DEDIHTANERRLKELIG   GKLHTGRSRNDQVATD RLW R  +    E     I  +  RA +E+EIL PGYTH+Q+AQPIRWSHWL+S+  ++ RD  R  D+ KR+++ PLGSGA+AGNPF IDR+ L +EL+F  +S+NS+D    RD++
Sbjct:    7 NKLWGGRFVGNTDPIMEKFNASISYDQRMWKADIKGSKAYVKALQKASLVTQNEMEQILTGLDKVLDEWSKGEFEIKPGDEDIHTANERRLKELIGDAAGKLHTGRSRNDQVATDMRLWLRDGIATLKELALQLINTMVERAAAEIEILCPGYTHMQRAQPIRWSHWLLSHVVAISRDVERLEDIRKRVNVMPLGSGAIAGNPFDIDRELLRQELSFDSISINSMDATGQRDFV 240

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Zebrafish
Match: CABZ01084963.1 (fumarate hydratase, mitochondrial-like [Source:NCBI gene;Acc:100535417])

HSP 1 Score: 52.7582 bits (125), Expect = 4.648e-7
Identity = 49/218 (22.48%), Postives = 91/218 (41.74%), Query Frame = 2

Query:  425 RSRNDQVATDTRLWCRQWVLK-FLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRI-DICPLGSGALAGNPFKI-------DRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVR--ISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGT 1045
            +S ND   T   +   + V +  L  ++     +A +A    +I+  G TH Q A P+        Y   +K   +R    + R+ ++   G+    G   +I       D+ S    L F   + N  + +++ D +VEL       A+++ ++A D+    +   S +   I      GSS+MP K NP   E +     ++ G  +G  +T+ G+
Sbjct:    7 QSSNDTFPTAMHIAAAKEVHEVLLPGLQTLHDALAAKAEQFKDIIKIGRTHTQDAVPLSLGQEFGGYVQQVKYSIARVKASLPRVYELAAGGTAVGTGLNTRIGFAEKVADKVSALTGLPFVTAA-NKFEALAAHDALVELSGALNTVAVSMMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVG--VTVGGS 221

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Zebrafish
Match: fh (fumarate hydratase [Source:NCBI gene;Acc:393938])

HSP 1 Score: 50.8322 bits (120), Expect = 3.556e-6
Identity = 48/218 (22.02%), Postives = 91/218 (41.74%), Query Frame = 2

Query:  425 RSRNDQVATDTRLWCRQWVLK-FLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRI-DICPLGSGALAGNPFKI-------DRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISD--AYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGT 1045
            +S ND   T   +   + V +  L  ++     +A +A    +I+  G TH Q A P+        Y   +K   +R    + R+ ++   G+    G   +I       D+ S    L F   + N  + +++ D +VEL       A+++ ++A D+    +   S +   +      GSS+MP K NP   E +     ++ G  +  A+T+ G+
Sbjct:  184 QSSNDTFPTAMHIAAAKEVHEVLLPGLQTLHDALAAKAEQFKDIIKIGRTHTQDAVPLSLGQEFGGYVQQVKYSIARVKASLPRVYELAAGGTAVGTGLNTRIGFAEKVADKVSALTGLPFVTAA-NKFEALAAHDALVELSGALNTVAVSMMKIANDIRFLGSGPRSGLGELNLPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHV--AVTVGGS 398

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Xenopus
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:100127798])

HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0
Identity = 260/452 (57.52%), Postives = 335/452 (74.12%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            LWGGRF G +DPIME FN S+ +D+R+W  DI GS+AY  A+ K  L++  E  ++ +GLD+I +EW    F L + DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R         +   I+ +  RA  E+ IL PGYTH+Q+AQPIRWSHW++S+A +L RD  R  ++ KR++I PLGSGA+AGNP  +DR+ L KEL+F  +S+NS+D  S RD+I E    A++C  +LS+++EDLIIYSTKEF FV +SD+YSTGSSLMPQKKNPDSLELIRGK GR+ G+  GF  TLKG PSTYNKD QEDKE++FD+ DT+ +++++A+GV+ATL+++K     ALSPDMLATDIAYYLVRKG+PFR AHG+SGK V L+E  G S+  L+L  + SI  LF  DV K+W+Y NSVEQY+  GGT+  SV  QI+++  W+
Sbjct:    8 LWGGRFVGSIDPIMEMFNCSVTYDQRMWSADIRGSQAYVKALEKAGLVSKPEMEQITSGLDKIHDEWSTGTFALTKGDEDIHTANERRLKELIGEVAGKLHTGRSRNDQVVTDMRLWLRDSCSTLYTHLTHLIQTMVERAAIEVNILFPGYTHMQRAQPIRWSHWILSHAVALSRDAERLGEVKKRVNILPLGSGAIAGNPLGVDRELLRKELHFDSLSLNSMDATSERDFIAEFLFWASLCMTHLSKMSEDLIIYSTKEFGFVTLSDSYSTGSSLMPQKKNPDSLELIRGKTGRVFGRCSGFLTTLKGLPSTYNKDLQEDKEAMFDVYDTVCAVLQVASGVIATLQINKEAMEKALSPDMLATDIAYYLVRKGMPFRQAHGVSGKVVQLAETKGISVDKLSLEDMKSISPLFSGDVSKVWDYTNSVEQYTAAGGTAKSSVLVQIEQLRTWM 459

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Xenopus
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:100127798])

HSP 1 Score: 527.709 bits (1358), Expect = 0.000e+0
Identity = 252/456 (55.26%), Postives = 328/456 (71.93%), Query Frame = 2

Query:  104 TEHSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            T + LWGGRF G +DPIME FN S+ +D+R+W  DI GS+AY  A+ K  L++  E  ++ +GLD+I +EW    F L + DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R         +   I+ +  RA  E+ IL PGYTH+Q+AQPIRWSHW++S+A +L RD  R  ++ KR++I PL    L+  PF++       EL+F  +S+NS+D  S RD+I E    A++C  +LS+++EDLIIYSTKEF FV +SD+YSTGSSLMPQKKNPDSLELIRGK GR+ G+  GF  TLKG PSTYNKD QEDKE++FD+ DT+ +++++A+GV+ATL+++K     ALSPDMLATDIAYYLVRKG+PFR AHG+SGK V L+E  G S+  L+L  + SI  LF  DV K+W+Y NSVEQY+  GGT+  SV  QI+++  W+
Sbjct:    4 TGNKLWGGRFVGSIDPIMEMFNCSVTYDQRMWSADIRGSQAYVKALEKAGLVSKPEMEQITSGLDKIHDEWSTGTFALTKGDEDIHTANERRLKELIGEVAGKLHTGRSRNDQVVTDMRLWLRDSCSTLYTHLTHLIQTMVERAAIEVNILFPGYTHMQRAQPIRWSHWILSHAVALSRDAERLGEVKKRVNILPLVH--LSFFPFQL-------ELHFDSLSLNSMDATSERDFIAEFLFWASLCMTHLSKMSEDLIIYSTKEFGFVTLSDSYSTGSSLMPQKKNPDSLELIRGKTGRVFGRCSGFLTTLKGLPSTYNKDLQEDKEAMFDVYDTVCAVLQVASGVIATLQINKEAMEKALSPDMLATDIAYYLVRKGMPFRQAHGVSGKVVQLAETKGISVDKLSLEDMKSISPLFSGDVSKVWDYTNSVEQYTAAGGTAKSSVLVQIEQLRTWM 450

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Xenopus
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:100127798])

HSP 1 Score: 527.324 bits (1357), Expect = 0.000e+0
Identity = 254/463 (54.86%), Postives = 330/463 (71.27%), Query Frame = 2

Query:   83 FSLNNLMTEHSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            FS N     + LWGGRF G +DPIME FN S+ +D+R+W  DI GS+AY  A+ K  L++  E  ++ +GLD+I +EW    F L + DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R         +   I+ +  RA  E+ IL PGYTH+Q+AQPIRWSHW++S+A +L RD  R  ++ KR++I PL    L+  PF++       EL+F  +S+NS+D  S RD+I E    A++C  +LS+++EDLIIYSTKEF FV +SD+YSTGSSLMPQKKNPDSLELIRGK GR+ G+  GF  TLKG PSTYNKD QEDKE++FD+ DT+ +++++A+GV+ATL+++K     ALSPDMLATDIAYYLVRKG+PFR AHG+SGK V L+E  G S+  L+L  + SI  LF  DV K+W+Y NSVEQY+  GGT+  SV  QI+++  W+
Sbjct:    1 FSANG----NKLWGGRFVGSIDPIMEMFNCSVTYDQRMWSADIRGSQAYVKALEKAGLVSKPEMEQITSGLDKIHDEWSTGTFALTKGDEDIHTANERRLKELIGEVAGKLHTGRSRNDQVVTDMRLWLRDSCSTLYTHLTHLIQTMVERAAIEVNILFPGYTHMQRAQPIRWSHWILSHAVALSRDAERLGEVKKRVNILPLVH--LSFFPFQL-------ELHFDSLSLNSMDATSERDFIAEFLFWASLCMTHLSKMSEDLIIYSTKEFGFVTLSDSYSTGSSLMPQKKNPDSLELIRGKTGRVFGRCSGFLTTLKGLPSTYNKDLQEDKEAMFDVYDTVCAVLQVASGVIATLQINKEAMEKALSPDMLATDIAYYLVRKGMPFRQAHGVSGKVVQLAETKGISVDKLSLEDMKSISPLFSGDVSKVWDYTNSVEQYTAAGGTAKSSVLVQIEQLRTWM 450

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Xenopus
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:100127798])

HSP 1 Score: 527.324 bits (1357), Expect = 0.000e+0
Identity = 251/457 (54.92%), Postives = 329/457 (71.99%), Query Frame = 2

Query:  101 MTEHSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            ++ + LWGGRF G +DPIME FN S+ +D+R+W  DI GS+AY  A+ K  L++  E  ++ +GLD+I +EW    F L + DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R         +   I+ +  RA  E+ IL PGYTH+Q+AQPIRWSHW++S+A +L RD  R  ++ KR++I PL    L+  PF++       EL+F  +S+NS+D  S RD+I E    A++C  +LS+++EDLIIYSTKEF FV +SD+YSTGSSLMPQKKNPDSLELIRGK GR+ G+  GF  TLKG PSTYNKD QEDKE++FD+ DT+ +++++A+GV+ATL+++K     ALSPDMLATDIAYYLVRKG+PFR AHG+SGK V L+E  G S+  L+L  + SI  LF  DV K+W+Y NSVEQY+  GGT+  SV  QI+++  W+
Sbjct:    1 LSGNKLWGGRFVGSIDPIMEMFNCSVTYDQRMWSADIRGSQAYVKALEKAGLVSKPEMEQITSGLDKIHDEWSTGTFALTKGDEDIHTANERRLKELIGEVAGKLHTGRSRNDQVVTDMRLWLRDSCSTLYTHLTHLIQTMVERAAIEVNILFPGYTHMQRAQPIRWSHWILSHAVALSRDAERLGEVKKRVNILPLVH--LSFFPFQL-------ELHFDSLSLNSMDATSERDFIAEFLFWASLCMTHLSKMSEDLIIYSTKEFGFVTLSDSYSTGSSLMPQKKNPDSLELIRGKTGRVFGRCSGFLTTLKGLPSTYNKDLQEDKEAMFDVYDTVCAVLQVASGVIATLQINKEAMEKALSPDMLATDIAYYLVRKGMPFRQAHGVSGKVVQLAETKGISVDKLSLEDMKSISPLFSGDVSKVWDYTNSVEQYTAAGGTAKSSVLVQIEQLRTWM 448

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Xenopus
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:100127798])

HSP 1 Score: 526.554 bits (1355), Expect = 0.000e+0
Identity = 251/452 (55.53%), Postives = 326/452 (72.12%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            LWGGRF G +DPIME FN S+ +D+R+W  DI GS+AY  A+ K  L++  E  ++ +GLD+I +EW    F L + DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R         +   I+ +  RA  E+ IL PGYTH+Q+AQPIRWSHW++S+A +L RD  R  ++ KR++I PL    L+  PF++       EL+F  +S+NS+D  S RD+I E    A++C  +LS+++EDLIIYSTKEF FV +SD+YSTGSSLMPQKKNPDSLELIRGK GR+ G+  GF  TLKG PSTYNKD QEDKE++FD+ DT+ +++++A+GV+ATL+++K     ALSPDMLATDIAYYLVRKG+PFR AHG+SGK V L+E  G S+  L+L  + SI  LF  DV K+W+Y NSVEQY+  GGT+  SV  QI+++  W+
Sbjct:   15 LWGGRFVGSIDPIMEMFNCSVTYDQRMWSADIRGSQAYVKALEKAGLVSKPEMEQITSGLDKIHDEWSTGTFALTKGDEDIHTANERRLKELIGEVAGKLHTGRSRNDQVVTDMRLWLRDSCSTLYTHLTHLIQTMVERAAIEVNILFPGYTHMQRAQPIRWSHWILSHAVALSRDAERLGEVKKRVNILPLVH--LSFFPFQL-------ELHFDSLSLNSMDATSERDFIAEFLFWASLCMTHLSKMSEDLIIYSTKEFGFVTLSDSYSTGSSLMPQKKNPDSLELIRGKTGRVFGRCSGFLTTLKGLPSTYNKDLQEDKEAMFDVYDTVCAVLQVASGVIATLQINKEAMEKALSPDMLATDIAYYLVRKGMPFRQAHGVSGKVVQLAETKGISVDKLSLEDMKSISPLFSGDVSKVWDYTNSVEQYTAAGGTAKSSVLVQIEQLRTWM 457

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Mouse
Match: Asl (argininosuccinate lyase [Source:MGI Symbol;Acc:MGI:88084])

HSP 1 Score: 565.074 bits (1455), Expect = 0.000e+0
Identity = 258/448 (57.59%), Postives = 337/448 (75.22%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FN+SI +D+ LW  D+ GSKAY+  + K  LLT  E  +++ GLD++ EEW    F L+  DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW RQ   K    +++ I  +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM +++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV  +W+Y +SVEQYS LGGT+  SVE+QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQV 455

[Close]

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FN+SI +D+ LW  D+ GSKAY+  + K  LLT  E  +++ GLD++ EEW    F L+  DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW RQ   K    +++ I  +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM +++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV  +W+Y +SVEQYS LGGT+  SVE+QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQV 455

[Close]

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FN+SI +D+ LW  D+ GSKAY+  + K  LLT  E  +++ GLD++ EEW    F L+  DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW RQ   K    +++ I  +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM +++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV  +W+Y +SVEQYS LGGT+  SVE+QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQV 455

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Mouse
Match: Asl (argininosuccinate lyase [Source:MGI Symbol;Acc:MGI:88084])

HSP 1 Score: 312.383 bits (799), Expect = 1.678e-103
Identity = 141/255 (55.29%), Postives = 183/255 (71.76%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLII 880
            LWGGRF G VDPIME FN+SI +D+ LW  D+ GSKAY+  + K  LLT  E  +++ GLD++ EEW    F L+  DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW RQ   K    +++ I  +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+
Sbjct:    8 LWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLIL 262

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Mouse
Match: Asl (argininosuccinate lyase [Source:MGI Symbol;Acc:MGI:88084])

HSP 1 Score: 309.301 bits (791), Expect = 3.495e-102
Identity = 145/257 (56.42%), Postives = 195/257 (75.88%), Query Frame = 2

Query:  707 AGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYI------VELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            AGNP  +DR+ L  ELNF  +++NS+D  S RD++       E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM +++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV  +W+Y +SVEQYS LGGT+  SVE+QI+++
Sbjct:    2 AGNPLGVDRELLRAELNFGAITLNSMDATSERDFVGLLSLPAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQV 258

[Close]

BLAST of Argininosuccinate lyase vs. UniProt/SwissProt
Match: sp|Q91YI0|ARLY_MOUSE (Argininosuccinate lyase OS=Mus musculus OX=10090 GN=Asl PE=1 SV=1)

HSP 1 Score: 565.074 bits (1455), Expect = 0.000e+0
Identity = 258/448 (57.59%), Postives = 337/448 (75.22%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FN+SI +D+ LW  D+ GSKAY+  + K  LLT  E  +++ GLD++ EEW    F L+  DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW RQ   K    +++ I  +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM +++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV  +W+Y +SVEQYS LGGT+  SVE+QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQV 455

[Close]

BLAST of Argininosuccinate lyase vs. UniProt/SwissProt
Match: sp|P51464|ARLY_LITCT (Argininosuccinate lyase OS=Lithobates catesbeianus OX=8400 GN=ASL PE=3 SV=1)

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 262/452 (57.96%), Postives = 338/452 (74.78%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            LWGGRF G +DPIME FN+S+ +D+R+W  DI GS+AY  A+ K  L++  E   ++ GLDQI EEW    F+L + DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R         +   I+ +  RA  E++IL PGYTH+Q+AQPIRWSHW++S+A +L RD  R  +L KRI++ PLGSGA+AGNP  +DR+ L KEL F  VS+NS+D  S RD+I E    A++C  +LS+++EDLIIYSTKEFSFV +SD+YSTGSSLMPQKKNPDSLELIR K GR+ G+  GF +TLKG PSTYNKD QEDKE++FD+ DT+ +++++A+GV++TL+++K     ALSPDMLATDIAYYLVRKG+PFR AHG+SGK V L+E  G +++ L+L  L SI  LF +DV K+WNY NSVEQY+  GGT+   V  Q++++  W+
Sbjct:    8 LWGGRFVGSIDPIMEMFNSSVSYDQRMWSADIRGSQAYVKALEKAGLVSPTEMEHILTGLDQIHEEWSKGTFVLTKADEDIHTANERRLKELIGEPAGKLHTGRSRNDQVVTDMRLWLRDSCSALHLHLTRLIRTMVDRAAIEIDILFPGYTHMQRAQPIRWSHWILSHAVALCRDAERLGELRKRINVLPLGSGAIAGNPLGVDRELLRKELEFDSVSLNSMDATSERDFIAEFLFWASLCMTHLSKMSEDLIIYSTKEFSFVTLSDSYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCSGFLMTLKGLPSTYNKDLQEDKEAMFDVYDTVCAVLQVASGVISTLQINKEGMEKALSPDMLATDIAYYLVRKGMPFRQAHGLSGKVVQLAETKGIALNKLSLEDLKSISPLFSNDVSKVWNYTNSVEQYTAAGGTAKSCVVAQVEQLRTWL 459

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BLAST of Argininosuccinate lyase vs. UniProt/SwissProt
Match: sp|P04424|ARLY_HUMAN (Argininosuccinate lyase OS=Homo sapiens OX=9606 GN=ASL PE=1 SV=4)

HSP 1 Score: 561.222 bits (1445), Expect = 0.000e+0
Identity = 258/448 (57.59%), Postives = 338/448 (75.45%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FNASI +D+ LW  D+ GSKAY+  + K  LLT  E ++++ GLD++ EEW    F LN  DEDIHTANERRLKELIG T GKLHTGRSRNDQV TD RLW RQ        +   I+ +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM++++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV+ +W+Y +SVEQY  LGGT+  SV++QI+++
Sbjct:    8 LWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQV 455

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BLAST of Argininosuccinate lyase vs. UniProt/SwissProt
Match: sp|P20673|ARLY_RAT (Argininosuccinate lyase OS=Rattus norvegicus OX=10116 GN=Asl PE=2 SV=1)

HSP 1 Score: 558.525 bits (1438), Expect = 0.000e+0
Identity = 255/448 (56.92%), Postives = 336/448 (75.00%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF+G VDP M+ FN+SI +D+ LW  D+ GSKAY+  + K  LLT  E  +++ GLD++ EEW    F L   DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW RQ   K    +K+ I+ +  RA +E E+L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  ELNF  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEF+FV++SDAYSTGSSLMPQKKNPDSLELIR K  R+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTMT+++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L ++  LF  DV  +W+Y +SVEQY+ LGGT+  SVE+QI ++
Sbjct:    8 LWGGRFAGSVDPTMDKFNSSIAYDRHLWNVDLQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGIFKLYPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTYSKLSTFLKVLIEAMVDRAEAECEVLFPGYTHLQRAQPIRWSHWILSHAVALTRDLERLKEVQKRINVLPLGSGAIAGNPLGVDREFLCAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFNFVQLSDAYSTGSSLMPQKKNPDSLELIRSKARRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMTAVLQVATGVISTLQIHRENMAQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVVVAEMKGVALNQLSLQELQTVSPLFSSDVNLVWDYSHSVEQYTALGGTAQSSVEWQISQV 455

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BLAST of Argininosuccinate lyase vs. UniProt/SwissProt
Match: sp|Q3SZJ0|ARLY_BOVIN (Argininosuccinate lyase OS=Bos taurus OX=9913 GN=ASL PE=2 SV=1)

HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0
Identity = 256/448 (57.14%), Postives = 336/448 (75.00%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF G VDPIME FN+SI +D+ LW  D+ GSKAY+  + K  LLT  E ++++ GLD++ EEW    F LN  DEDIHTANERRLKELIG T GKLHTGRSRNDQV TD RLW RQ        +   I+ +  RA +E ++L PGYTHLQ+AQPIRWSHW++S+A +L RD  R  ++ KRI++ PLGSGA+AGNP  +DR+ L  EL+F  +++NS+D  S RD++ E    A++C  +LSR+AEDLI+Y TKEFSFV++SDAYSTGSSLMPQKKNPDSLELIR K GR+ G+  G  +TLKG PSTYNKD QEDKE++F++ DTM++++++ATGV++TL++ +     ALSPDMLATD+AYYLVRKG+PFR AH  SGK V ++E  G +++ L+L +L +I  LF  DV  +W+Y +SVEQY  LGGT+  SV++QI ++
Sbjct:    8 LWGGRFVGTVDPIMEKFNSSITYDRHLWEADVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNPNDEDIHTANERRLKELIGETAGKLHTGRSRNDQVVTDLRLWMRQNCSMLSALLCELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELDFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHRENMGRALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVSHVWDYGHSVEQYEALGGTARSSVDWQIGQL 455

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BLAST of Argininosuccinate lyase vs. TrEMBL
Match: A0A210Q843 (Argininosuccinate lyase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT16713 PE=3 SV=1)

HSP 1 Score: 596.66 bits (1537), Expect = 0.000e+0
Identity = 284/457 (62.14%), Postives = 349/457 (76.37%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLC----IKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWVD 1474
            LWGGRF+G  DP+MEAFNASI +DKR+WR DI GSKAY +AI K  L+TV+E++ +  GLD++ EEW ND F +   DEDIHTANERRLKELIGPT GKLHTGRSRNDQV TD RLW R      L ++K C    IKV+  RA  E+++LMPGYTHLQ+AQPIRWSHWL+SYA  LKRD  R  +L +R++I PLGSGALAGNPF +DR  LAKEL F+ +S NSLD VS RD++ E    A++  I+LSR AEDLI+Y +KEF F+ +SDAYSTGSSLMPQKKN DSLELIRGK GR+ G+  GF +TLKG PSTYNKD QEDKES+FD   T++ ++K++TGVL+TL++   K   ALSPDMLATDIAYYLVRKGVPFR AHG+SG CVA++E   C +S LTL  L S+   FE+D++K+W+Y+NSV+QY   GGT   SV  QI+ +  W+D
Sbjct:   19 LWGGRFTGNTDPVMEAFNASIHYDKRMWRADIQGSKAYVSAIQKAGLVTVQERDAIREGLDKVAEEWANDVFEIRPGDEDIHTANERRLKELIGPTAGKLHTGRSRNDQVTTDMRLWLRD----ALTELKTCVIDLIKVMINRAKLEIDVLMPGYTHLQRAQPIRWSHWLLSYAWMLKRDVERLMELSERVNILPLGSGALAGNPFAVDRDFLAKELGFSQISGNSLDAVSDRDFVAEYLFWASMLGIHLSRWAEDLILYCSKEFGFISLSDAYSTGSSLMPQKKNADSLELIRGKSGRLFGKFSGFMMTLKGLPSTYNKDLQEDKESMFDTYTTLSGVLKVSTGVLSTLQIHPEKMRGALSPDMLATDIAYYLVRKGVPFRQAHGLSGTCVAMAETKQCPLSDLTLEDLKSVSPCFEEDIVKLWDYDNSVDQYKAYGGTGKVSVSQQIQSLSTWLD 471

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BLAST of Argininosuccinate lyase vs. TrEMBL
Match: V4B241 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_200177 PE=3 SV=1)

HSP 1 Score: 589.341 bits (1518), Expect = 0.000e+0
Identity = 283/455 (62.20%), Postives = 354/455 (77.80%), Query Frame = 2

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLED-IKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            + LWGGRF+GK DPIME FNASI +DK++W+ DI GS+AY  AI KV L+T EE+  +  GL +I++EWEN++FI+   DEDIHTANERRLKELIG   GKLHTGRSRNDQVATD RLW +   LK L   +   +KVI  RA  E+++LMPGYTHLQ+AQPIRWSHWL+SYA  L+RD  R+ +L KR  + PLGSGALAGNPF +DR+ LAKEL+  +VS NSLD VS RD+IVE    +++ + +LSR AEDLI+Y TKEF+FV +SDAYSTGSSLMPQKKN DSLELIRGK GR+ G   GF +TLKG PSTYNKDFQEDK ++FD  +T++ ++K+ATGVL+TL +       ALSPDMLATD+AYYLVRKGVPFR+AHG++G CVAL+EK GC++S LT+    SI  LF+ DV ++WNYENSV QY+ +GGT  +SV  QI+++ KW+
Sbjct:    8 NKLWGGRFTGKTDPIMEEFNASISYDKKMWKADIRGSQAYVKAIEKVGLVTSEEREAIYNGLGKIEKEWENNEFIIKAGDEDIHTANERRLKELIGSASGKLHTGRSRNDQVATDMRLWLKD-SLKILTGLVSDFMKVILKRAAVEIDVLMPGYTHLQRAQPIRWSHWLLSYAWMLQRDLERYDELAKRTAVLPLGSGALAGNPFGVDREFLAKELDMLNVSGNSLDAVSDRDFIVEFLFVSSLLSTHLSRWAEDLILYCTKEFNFVALSDAYSTGSSLMPQKKNADSLELIRGKSGRMFGNCSGFMMTLKGVPSTYNKDFQEDKTAMFDTYETLSGILKVATGVLSTLTIHPEAMRAALSPDMLATDLAYYLVRKGVPFREAHGLAGGCVALAEKKGCAMSDLTVDDFKSIHALFDSDVTQVWNYENSVNQYNAIGGTGKQSVVQQIEKLEKWI 461

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BLAST of Argininosuccinate lyase vs. TrEMBL
Match: A0A1S3HB96 (argininosuccinate lyase OS=Lingula unguis OX=7574 GN=LOC106153743 PE=3 SV=1)

HSP 1 Score: 588.186 bits (1515), Expect = 0.000e+0
Identity = 272/452 (60.18%), Postives = 346/452 (76.55%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            LWGGRF+GK DP+ME FNASI +DKRLW+ DI GS+AY  A+ +  L++ EE+  +  GL+++  EW  D+F+L   DEDIHTANERRLKELIG   GKLHTGRSRNDQVATD RLW R+ +      +   I+VI TRA  ++ ILMPGYTHLQ+AQPIRWSHWL+SYA  L+RD  R   LM R+++ PLG GALAGNPF +DR+ LA+ELNF  V++NSLDG S RD++ E    A++ +++LS+ AEDLIIYSTKEFSFV ++DAYSTGSSLMPQKKNPDSLELIRGK GR+ G+     +TLKG PSTYNKD QEDKE +FD+CDTMT ++++A GV++TL+V++  C  ALSPDMLATD+AY+LV KGVPFR+AH +SG+CVAL+EK  C +S L++    S+   F+  V K+W+YENSVEQY  +GGTS  SV+ QI  +  W+
Sbjct:   11 LWGGRFTGKTDPVMEQFNASISYDKRLWKADIQGSQAYVKALEQAGLVSPEERLAIHHGLEKVAIEWSEDRFVLQPSDEDIHTANERRLKELIGSAAGKLHTGRSRNDQVATDMRLWLREQLQILRSFMVQLIQVICTRAQQDIHILMPGYTHLQRAQPIRWSHWLLSYAFMLQRDVQRLDQLMDRVNVLPLGCGALAGNPFNVDRQLLARELNFPAVALNSLDGTSDRDFVAEFLFWASMTSVHLSKWAEDLIIYSTKEFSFVLLADAYSTGSSLMPQKKNPDSLELIRGKSGRMYGRCTSLMMTLKGLPSTYNKDLQEDKEGMFDVCDTMTGVLQVAIGVISTLKVNQEACLAALSPDMLATDLAYFLVNKGVPFREAHSLSGECVALAEKKQCKLSELSVRDFESVSASFDASVTKVWDYENSVEQYRSIGGTSRASVQQQIARLQVWL 462

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BLAST of Argininosuccinate lyase vs. TrEMBL
Match: A0A2T7PHM6 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_08361 PE=3 SV=1)

HSP 1 Score: 581.637 bits (1498), Expect = 0.000e+0
Identity = 272/452 (60.18%), Postives = 347/452 (76.77%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            LWGGRF+G  DP+MEAFNASI +DKR+W+ DI+GS+AY  ++ KV ++T EE   +I GLD++KEEW N  F +  QDEDIHTANERRLKEL+G  GGKLHTGRSRNDQVATD RLW    VL     +   + V+  RA +E+++LMPGYTHLQ+AQPIRWSHWLMSYA  + RD  R   L +R+   PLGSGALAGNPF +DR+ L +EL  + VS NSLD VS RD++VE    A++ +I+LSR AEDL++YSTKEF+F+ +SDAYSTGSSLMPQKKN DSLELIRGK GRI G   GF ++LKG PSTYNKD QEDKE++FD  DT+  ++++ATGVL+TL++ +    +ALSPDMLATD+AYYLV+KG PFRDAH I+G+CVAL+EK GC +S L+L  + ++ +LFE+DV  +WNY +SV+QYS  GGT+  SV+ QI  +  W+
Sbjct:   11 LWGGRFTGATDPVMEAFNASIGYDKRMWKADIEGSQAYVKSLQKVGIVTAEECQTIIQGLDKVKEEWMNGCFEIKPQDEDIHTANERRLKELVGVVGGKLHTGRSRNDQVATDMRLWLGDAVLSLRGHLVSLLSVMCRRAEAELDVLMPGYTHLQRAQPIRWSHWLMSYAWMVHRDVQRLDQLRERVLTLPLGSGALAGNPFNVDRQFLRQELGMSSVSQNSLDAVSDRDFVVEFLFWASLLSIHLSRWAEDLVLYSTKEFAFITLSDAYSTGSSLMPQKKNSDSLELIRGKSGRIYGNCCGFMMSLKGIPSTYNKDLQEDKEAMFDTYDTLMGVLQVATGVLSTLKIDRKAMEEALSPDMLATDLAYYLVKKGKPFRDAHSIAGECVALAEKKGCILSDLSLEDMKTVNNLFEEDVASVWNYSHSVDQYSAEGGTAASSVKEQISALSAWL 462

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BLAST of Argininosuccinate lyase vs. TrEMBL
Match: R7TU56 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_159436 PE=3 SV=1)

HSP 1 Score: 581.252 bits (1497), Expect = 0.000e+0
Identity = 274/440 (62.27%), Postives = 342/440 (77.73%), Query Frame = 2

Query:  155 MEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWVD 1474
            ME FNASI +DKR+WR DI GSKAY  AI+KV L+T +EK+ +IAGLDQ+ EEWE  KF+L   DEDIHTANERRLKE++G   GKLHTGRSRNDQVATD RLW R  V      ++  I V   RA  E+++L+PGYTHLQ+AQPIRWSHWL+SYA  LKRD  R ++L +R++I PLGSGALAGNPF +DR  LA+EL F  VS NSLD +S RD++VE+   A++ A +LSRLAEDLIIYSTKEF+F+ +SDAYSTGSSLMPQKKN DSLELIRGK GRI G+  GF ++LKG PSTYNKD QEDKE++FD CD++  L+++ TG L+TL V    C  ALSPDMLATD+AYYLVRKG+PFR+AHG+SG+CVA +E+  C+++ LT+  L +I   F DDV+K+W+YE SVEQY   GGTS  SV+ QI+++  W++
Sbjct:    1 MEEFNASISYDKRMWRADIMGSKAYVAAIHKVGLVTEKEKSAIIAGLDQVAEEWEAGKFVLKAGDEDIHTANERRLKEIVGAPAGKLHTGRSRNDQVATDMRLWLRDEVQVLEGHLRSLIAVFVNRAIMEIDVLLPGYTHLQRAQPIRWSHWLLSYAWMLKRDMQRLHELKQRLNILPLGSGALAGNPFNVDRNFLAQELGFDGVSGNSLDAISDRDFVVEILMWASLNATHLSRLAEDLIIYSTKEFAFISLSDAYSTGSSLMPQKKNADSLELIRGKSGRIFGRCAGFMMSLKGLPSTYNKDLQEDKEAMFDACDSLGRLLQVTTGTLSTLTVHAEVCKQALSPDMLATDLAYYLVRKGIPFREAHGLSGQCVAFAEEKKCALNELTVQDLQTISGSFSDDVMKVWDYEYSVEQYQSAGGTSRASVQKQIEQLNAWLN 440

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BLAST of Argininosuccinate lyase vs. Ensembl Cavefish
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:103043433])

HSP 1 Score: 548.51 bits (1412), Expect = 0.000e+0
Identity = 256/452 (56.64%), Postives = 330/452 (73.01%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            LWGGRF G  DPIME FNASI +D+R+W  DI GSKAY  A+ K  L+T EE  ++++GLD++  EW N +F +   DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R  +     +    I  +  RA  E++IL PGYTH+Q+AQPIRWSHW++S+A +L RD  +  ++ +R+++ PLGSGA+AGNPF IDR+ L KELNF D+S+NS+D    RD++ E     ++C  +LS++AEDLI+YSTKEFSF+ +SDAYSTGSSLMPQKKN DSLELIR K GR+ G+  GF +TLKG PSTYNKD QEDKE++FD  DT  +++++ATGV++TL+V+      ALSPDMLATD+AYYLVRKGVPFR+AH  SGK V  +E     ++ LT+  L +   LF+ DV  +W+Y +SVEQYS  GGT+  SV  QI+ M  W+
Sbjct:    9 LWGGRFVGNTDPIMEKFNASIAYDQRMWDADIRGSKAYVKALQKAGLVTPEEMQQILSGLDKVFGEWSNGEFQIKPGDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDMRLWLRDAITTLKGNAIELINTMVERAAVEIDILFPGYTHMQRAQPIRWSHWILSHAVALSRDVEQVEEIRRRVNVLPLGSGAIAGNPFNIDRELLRKELNFDDISINSMDATGQRDFVAEFLFWGSMCLTHLSKMAEDLILYSTKEFSFISLSDAYSTGSSLMPQKKNADSLELIRSKAGRVFGRCAGFLMTLKGLPSTYNKDLQEDKEAMFDTYDTAHAVLQVATGVMSTLKVNPKSMEAALSPDMLATDLAYYLVRKGVPFREAHSCSGKAVYQAESKNVPLNQLTVEDLHTASPLFDSDVSSVWDYTSSVEQYSAPGGTAKSSVTAQIEHMRTWL 460

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Cavefish
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:103043433])

HSP 1 Score: 536.569 bits (1381), Expect = 0.000e+0
Identity = 251/447 (56.15%), Postives = 325/447 (72.71%), Query Frame = 2

Query:  131 FSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            F G  DPIME FNASI +D+R+W  DI GSKAY  A+ K  L+T EE  ++++GLD++  EW N +F +   DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R  +     +    I  +  RA  E++IL PGYTH+Q+AQPIRWSHW++S+A +L RD  +  ++ +R+++ PLGSGA+AGNPF IDR+ L KELNF D+S+NS+D    RD++ E     ++C  +LS++AEDLI+YSTKEFSF+ +SDAYSTGSSLMPQKKN DSLELIR K GR+ G+  GF +TLKG PSTYNKD QEDKE++FD  DT  +++++ATGV++TL+V+      ALSPDMLATD+AYYLVRKGVPFR+AH  SGK V  +E     ++ LT+  L +   LF+ DV  +W+Y +SVEQYS  GGT+  SV  QI+ M  W+
Sbjct:    2 FVGNTDPIMEKFNASIAYDQRMWDADIRGSKAYVKALQKAGLVTPEEMQQILSGLDKVFGEWSNGEFQIKPGDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDMRLWLRDAITTLKGNAIELINTMVERAAVEIDILFPGYTHMQRAQPIRWSHWILSHAVALSRDVEQVEEIRRRVNVLPLGSGAIAGNPFNIDRELLRKELNFDDISINSMDATGQRDFVAEFLFWGSMCLTHLSKMAEDLILYSTKEFSFISLSDAYSTGSSLMPQKKNADSLELIRSKAGRVFGRCAGFLMTLKGLPSTYNKDLQEDKEAMFDTYDTAHAVLQVATGVMSTLKVNPKSMEAALSPDMLATDLAYYLVRKGVPFREAHSCSGKAVYQAESKNVPLNQLTVEDLHTASPLFDSDVSSVWDYTSSVEQYSAPGGTAKSSVTAQIEHMRTWL 448

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000439.1 (pep scaffold:Pmarinus_7.0:GL480960:172212:183976:1 gene:ENSPMAG00000000373.1 transcript:ENSPMAT00000000439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 490.73 bits (1262), Expect = 2.988e-172
Identity = 229/388 (59.02%), Postives = 296/388 (76.29%), Query Frame = 2

Query:  299 QIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEML 1462
            QI++EWE  KF + E DEDIHTANERRLKELIG  GGKLHTGRSRNDQV TD R+W R+ +   L  +   ++ IA RA++EM++L PGYTHLQ+AQPIRWSHWL+S+A++L RD  R      R ++ PLGSGA+AGNP  IDR+ L KELNF  +S+NS+D  S RD+IV     A++   +LSR+AEDL++YS+KEF FV +SDAYSTGSSLMPQK+NPDSLELIRGK G + G+  G  +T+KG P+ YNKD QEDKE++FD+ DT++++++IATGV++TL V+K     ALSPDMLATD+AYYLVRKGV FRDAH ++G+ VA SE  GCS+  L++ +L +I  LF  DV  +W+YE+SVEQYS  GGT+  SV  QI+ +L
Sbjct:    3 QIEKEWEQGKFEVKENDEDIHTANERRLKELIGEAGGKLHTGRSRNDQVVTDVRIWLRESLSHLLALLHTLVRSIAQRAHAEMDVLCPGYTHLQRAQPIRWSHWLLSHATALLRDAERLAQARARTNVLPLGSGAIAGNPLNIDREVLRKELNFDSISLNSMDATSDRDFIVCDMVAASLTMTHLSRMAEDLVLYSSKEFGFVSLSDAYSTGSSLMPQKRNPDSLELIRGKTGTVFGRCAGLMMTMKGLPTAYNKDLQEDKEAMFDVYDTLSAVVQIATGVISTLTVNKAAMRAALSPDMLATDLAYYLVRKGVAFRDAHNLAGRAVAESEAKGCSLKDLSVDELQTISPLFGSDVCAVWDYESSVEQYSAPGGTARASVAQQIEAIL 390

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Yeast
Match: ARG4 (Argininosuccinate lyase; catalyzes the final step in the arginine biosynthesis pathway [Source:SGD;Acc:S000001060])

HSP 1 Score: 493.041 bits (1268), Expect = 3.186e-172
Identity = 246/451 (54.55%), Postives = 321/451 (71.18%), Query Frame = 2

Query:  116 LWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIG-PTGGKLHTGRSRNDQVATDTRLWCRQWVLKFL-EDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCS-ISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEM 1459
            LWGGRF+G+ DP+M  +NAS+ +D ++++ D++G+K Y   + K+ LLT  E  K+  GL +IK+EW+ DKF+ +  DEDIHTANERRL ELIG    GK+HTGRSRNDQV TD R++CR  V   L   +K  ++V+  RA  E+++LMPGYTHLQ+AQPIRWSHWL SYA+    DY R   ++ R++  PLG+GALAG+P+ IDR+ LA+ L F  V  NSL  VS RD+IVEL    T+   ++SR AEDLIIY T EF F+++SDAYSTGSSLMPQKKN DSLEL+RGK GR+ G + GF ++LKG PSTY+KD QEDKE LFD   T+   + IATGV++TL V+K K   AL+ DMLATD+A YLVRKGVPFR+ H ISG+CVA +E+LG S I  LTL Q   I   F  D+ + +N+E SVE+    GGT+  +V  Q+  +
Sbjct:    8 LWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTAGLQKLGLLTETELAKIHEGLAEIKKEWDADKFVRHPNDEDIHTANERRLGELIGRDIAGKVHTGRSRNDQVVTDLRIYCRDIVNDTLFPALKGLVEVLIKRAEGEIDVLMPGYTHLQRAQPIRWSHWLSSYATYFTEDYKRLGQILHRLNQSPLGAGALAGHPYGIDREFLAEGLGFNSVIGNSLVAVSDRDFIVELMFWGTLFMNHISRFAEDLIIYCTAEFGFIQLSDAYSTGSSLMPQKKNADSLELLRGKSGRVFGDLTGFLMSLKGIPSTYDKDMQEDKEPLFDCLTTVEHSMLIATGVISTLTVNKEKMEAALTMDMLATDLADYLVRKGVPFRETHHISGECVATAERLGLSGIDKLTLEQYQKIDSRFGQDLFETFNFEQSVERRDATGGTAKSAVLKQLDNL 458

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BLAST of Argininosuccinate lyase vs. Ensembl Nematostella
Match: EDO35208 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM51])

HSP 1 Score: 547.74 bits (1410), Expect = 0.000e+0
Identity = 264/442 (59.73%), Postives = 336/442 (76.02%), Query Frame = 2

Query:  155 MEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATD---TRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            MEAFNASI FDKR+W+ED+ GS+AY  AI KV L+T  E  +++ G+ +I+EEW++ KF +   DEDIHTANERRLKEL+G   GKLHTGRSRNDQV  D   + LW R  +    + +   I VI  RA+SE+E+L+PGYTHLQ+AQPIRWSHWL+SYA SLKRD  R  +L +R++I PLGSGALAGNPF +DR+ LA+EL F+DV+ NSLD VS RDYI E     ++ A +LSR AEDL++YST+EF FV++SDAYSTGSSLMPQKKN DSLELIRGK GRI G+  GF +TLKG PSTYNKD QEDKE LFD+CDT+  L+++ATGV+AT+ +   +    LSPDMLATD+AYYLVRKGVPFR+AH +SG  V L+E+ GC+++ LT   L  +  LFE++V  +WNY NSVEQY+  GGTS  +V+ Q+ ++  W+
Sbjct:    1 MEAFNASISFDKRMWKEDLKGSEAYVKAIEKVGLVTAAEMKQILDGIQKIREEWQSCKFQVICGDEDIHTANERRLKELVGSVAGKLHTGRSRNDQVMPDLMPSLLWLRGEIQVQRKLLTEFIDVIVKRASSEIEVLLPGYTHLQRAQPIRWSHWLLSYAWSLKRDVERLDELTERVNILPLGSGALAGNPFGVDRRFLAQELGFSDVTGNSLDAVSDRDYIAEFLFWGSLLATHLSRWAEDLLLYSTQEFGFVKLSDAYSTGSSLMPQKKNADSLELIRGKAGRIFGRCSGFLMTLKGLPSTYNKDLQEDKEPLFDVCDTLRGLLQVATGVIATITIDSERMLSCLSPDMLATDLAYYLVRKGVPFREAHALSGSAVHLAEQKGCALNELTAHDLQQVSTLFEENVKTVWNYGNSVEQYTAEGGTSKSAVQDQVTKLECWL 442

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Nematostella
Match: EDO31211 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYK1])

HSP 1 Score: 54.299 bits (129), Expect = 7.380e-8
Identity = 52/220 (23.64%), Postives = 91/220 (41.36%), Query Frame = 2

Query:  425 RSRNDQVATDTRLWCRQWVL-KFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALA---GNPFKIDRKSLAKELNFTDVSM----NSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKE---FSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIG--FAITLKGT 1045
            +S ND   T   + C   V  + L  +K     +  +A    +I+  G TH Q A P+        Y   ++   +R    M R+    +G  A+            K  AK   +T +      N  +G+++ D +VEL     + A +L ++A D+    +        +++ +    GSS+MP K NP   E I      +A Q+IG   A+++ G+
Sbjct:  173 QSSNDTFPTAMHVACAIEVHERLLPGLKKLHGALDAKAKEFKDIIKIGRTHTQDATPLTLGQEFSGYVKQIENGIARVQVCMPRVYELAIGGTAVGTGLNTRIGFAEKVSAKIAEYTKLPFTSNPNKFEGLAAHDAMVELHGALNVIACSLMKIANDVRFLGSGPRCGLGELQLPE-NEPGSSIMPGKVNPTQCEAIT----MVAAQVIGNQTAVSVGGS 387

[Close]

BLAST of Argininosuccinate lyase vs. Ensembl Medaka
Match: asl (argininosuccinate lyase [Source:NCBI gene;Acc:101156598])

HSP 1 Score: 550.436 bits (1417), Expect = 0.000e+0
Identity = 253/454 (55.73%), Postives = 333/454 (73.35%), Query Frame = 2

Query:  110 HSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWV 1471
            + LWGGRF G  DPIME FNASI +D+R+W  DI GSKAY  A+ K  L++ EEK +++ G+DQI EEW    F++   DEDIHTANERRLKELIG   GKLHTGRSRNDQV TD RLW R  +    E+    I  +  RA+ E+E+L PGYTH+Q+AQPIRWSHW++S++ +L RD  R  ++ KR+++ PLGSGA+AG P  IDR+ L KEL F  +S+NS+D    RD++VE    A++C  +LS++AEDL++YSTKEFSFV +SDAYSTGSSLMPQKKN DSLELIR K GR+ G+  GF +TLKG PSTYNKD QEDKE++F+  DT+ +++++ TGV++TL++++     ALSPDMLATD+AYYLVRKGVPFR+AHG+SGK V  +E    +++ LT   L  +  LF  DV  +W+Y +SVEQYS  GGT+  SV  Q++ +  W+
Sbjct:    7 NKLWGGRFVGDTDPIMEKFNASIGYDQRMWDADIRGSKAYVKALEKAQLVSSEEKEQILRGMDQISEEWSKGNFVIRPGDEDIHTANERRLKELIGAPAGKLHTGRSRNDQVVTDMRLWMRDAITTLTENSLQLISTMVERASVEIEVLFPGYTHMQRAQPIRWSHWILSHSVALSRDVDRLLEIKKRVNVLPLGSGAIAGTPLDIDRELLRKELGFDAISLNSMDATGQRDFVVEFLFWASLCLTHLSKMAEDLMLYSTKEFSFVTLSDAYSTGSSLMPQKKNADSLELIRSKAGRVFGRCAGFMMTLKGLPSTYNKDLQEDKEAMFECFDTVQAVLQVTTGVMSTLKINQNVMEAALSPDMLATDLAYYLVRKGVPFREAHGLSGKAVFKAESKNIALNRLTAEDLSDVSPLFGSDVSSVWDYSSSVEQYSAPGGTAKTSVVAQVEHLRNWL 460

[Close]

BLAST of Argininosuccinate lyase vs. Planmine SMEST
Match: SMESG000039074.1 (SMESG000039074.1)

HSP 1 Score: 951.044 bits (2457), Expect = 0.000e+0
Identity = 458/458 (100.00%), Postives = 458/458 (100.00%), Query Frame = 2

Query:  101 MTEHSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWVD 1474
            MTEHSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWVD
Sbjct:    1 MTEHSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKVNLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGPTGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEMEILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSGALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAINLSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGRIAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLATLEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLGCSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQIKEMLKWVD 458

The following BLAST results are available for this feature:

BLAST of Argininosuccinate lyase vs. Ensembl Human
BLAST of Argininosuccinate lyase vs. Ensembl Celegans
BLAST of Argininosuccinate lyase vs. Ensembl Fly
BLAST of Argininosuccinate lyase vs. Ensembl Zebrafish
BLAST of Argininosuccinate lyase vs. Ensembl Xenopus
BLAST of Argininosuccinate lyase vs. Ensembl Mouse
BLAST of Argininosuccinate lyase vs. UniProt/SwissProt
BLAST of Argininosuccinate lyase vs. TrEMBL
BLAST of Argininosuccinate lyase vs. Ensembl Cavefish
BLAST of Argininosuccinate lyase vs. Ensembl Sea Lamprey
BLAST of Argininosuccinate lyase vs. Ensembl Yeast
BLAST of Argininosuccinate lyase vs. Ensembl Nematostella
BLAST of Argininosuccinate lyase vs. Ensembl Medaka
BLAST of Argininosuccinate lyase vs. Planmine SMEST

BLAST of Argininosuccinate lyase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ASL	0.000e+0	57.59	argininosuccinate lyase [Source:HGNC Symbol;Acc:HG...	[more]
ASL	0.000e+0	57.59	argininosuccinate lyase [Source:HGNC Symbol;Acc:HG...	[more]
ASL	0.000e+0	54.69	argininosuccinate lyase [Source:HGNC Symbol;Acc:HG...	[more]
ASL	0.000e+0	54.91	argininosuccinate lyase [Source:HGNC Symbol;Acc:HG...	[more]
ASL	0.000e+0	54.91	argininosuccinate lyase [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fum-1	5.061e-6	21.03	Probable fumarate hydratase, mitochondrial [Sourc...	[more]
fum-1	5.061e-6	21.03	Probable fumarate hydratase, mitochondrial [Sourc...	[more]
fum-1	5.061e-6	21.03	Probable fumarate hydratase, mitochondrial [Sourc...	[more]
fum-1	5.061e-6	21.03	Probable fumarate hydratase, mitochondrial [Sourc...	[more]
fum-1	5.061e-6	21.03	Probable fumarate hydratase, mitochondrial [Sourc...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Argl	1.023e-152	46.46	gene:FBgn0032076 transcript:FBtr0100481	[more]
Argl	1.023e-152	46.46	gene:FBgn0032076 transcript:FBtr0299780	[more]
Argl	1.023e-152	46.46	gene:FBgn0032076 transcript:FBtr0340263	[more]
Fum4	1.025e-7	23.11	gene:FBgn0051874 transcript:FBtr0079964	[more]
Fum1	1.887e-6	25.34	gene:FBgn0286222 transcript:FBtr0070954	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
asl	0.000e+0	56.17	argininosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-...	[more]
asl	0.000e+0	56.17	argininosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-...	[more]
asl	6.874e-95	55.56	argininosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-...	[more]
CABZ01084963.1	4.648e-7	22.48	fumarate hydratase, mitochondrial-like [Source:NCB...	[more]
fh	3.556e-6	22.02	fumarate hydratase [Source:NCBI gene;Acc:393938]	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
asl	0.000e+0	57.52	argininosuccinate lyase [Source:NCBI gene;Acc:1001...	[more]
asl	0.000e+0	55.26	argininosuccinate lyase [Source:NCBI gene;Acc:1001...	[more]
asl	0.000e+0	54.86	argininosuccinate lyase [Source:NCBI gene;Acc:1001...	[more]
asl	0.000e+0	54.92	argininosuccinate lyase [Source:NCBI gene;Acc:1001...	[more]
asl	0.000e+0	55.53	argininosuccinate lyase [Source:NCBI gene;Acc:1001...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Asl	0.000e+0	57.59	argininosuccinate lyase [Source:MGI Symbol;Acc:MGI...	[more]
Asl	0.000e+0	57.59	argininosuccinate lyase [Source:MGI Symbol;Acc:MGI...	[more]
Asl	0.000e+0	57.59	argininosuccinate lyase [Source:MGI Symbol;Acc:MGI...	[more]
Asl	1.678e-103	55.29	argininosuccinate lyase [Source:MGI Symbol;Acc:MGI...	[more]
Asl	3.495e-102	56.42	argininosuccinate lyase [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of Argininosuccinate lyase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q91YI0\|ARLY_MOUSE	0.000e+0	57.59	Argininosuccinate lyase OS=Mus musculus OX=10090 G...	[more]
sp\|P51464\|ARLY_LITCT	0.000e+0	57.96	Argininosuccinate lyase OS=Lithobates catesbeianus...	[more]
sp\|P04424\|ARLY_HUMAN	0.000e+0	57.59	Argininosuccinate lyase OS=Homo sapiens OX=9606 GN...	[more]
sp\|P20673\|ARLY_RAT	0.000e+0	56.92	Argininosuccinate lyase OS=Rattus norvegicus OX=10...	[more]
sp\|Q3SZJ0\|ARLY_BOVIN	0.000e+0	57.14	Argininosuccinate lyase OS=Bos taurus OX=9913 GN=A...	[more]

BLAST of Argininosuccinate lyase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A210Q843	0.000e+0	62.14	Argininosuccinate lyase OS=Mizuhopecten yessoensis...	[more]
V4B241	0.000e+0	62.20	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
A0A1S3HB96	0.000e+0	60.18	argininosuccinate lyase OS=Lingula unguis OX=7574 ...	[more]
A0A2T7PHM6	0.000e+0	60.18	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]
R7TU56	0.000e+0	62.27	Uncharacterized protein OS=Capitella teleta OX=283...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
asl	0.000e+0	56.64	argininosuccinate lyase [Source:NCBI gene;Acc:1030...	[more]
asl	0.000e+0	56.15	argininosuccinate lyase [Source:NCBI gene;Acc:1030...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000000439.1	2.988e-172	59.02	pep scaffold:Pmarinus_7.0:GL480960:172212:183976:1...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
ARG4	3.186e-172	54.55	Argininosuccinate lyase; catalyzes the final step ...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO35208	0.000e+0	59.73	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31211	7.380e-8	23.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Argininosuccinate lyase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
asl	0.000e+0	55.73	argininosuccinate lyase [Source:NCBI gene;Acc:1011...	[more]

BLAST of Argininosuccinate lyase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000039074.1	0.000e+0	100.00	SMESG000039074.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030034 ID=SMED30030034|Name=Argininosuccinate lyase|organism=Schmidtea mediterranea sexual|type=transcript|length=1597bp
GAATATTTTGTTGACCTTGAATTCAATGTTGTTTTAAATAACAGTTTATA
AGATTCATCAAAATGGCAAATTTTGATTTCTTTTTTCTCTAAATAATTTA
ATGACTGAGCATTCTTTGTGGGGTGGCCGATTTTCTGGAAAGGTAGATCC
GATAATGGAGGCATTTAATGCTTCGATTAAGTTCGACAAGAGATTATGGA
GAGAAGATATTGATGGTAGCAAGGCTTACGCAAATGCAATTTATAAAGTG
AATCTATTGACTGTTGAAGAGAAAAATAAAATGATCGCCGGTCTCGATCA
AATAAAAGAAGAATGGGAAAACGATAAGTTCATTCTCAATGAACAGGATG
AAGATATCCACACAGCCAACGAACGACGTTTGAAAGAACTTATTGGCCCA
ACTGGTGGAAAGCTTCATACCGGAAGAAGTCGGAATGACCAAGTTGCTAC
AGATACAAGGTTATGGTGTCGTCAATGGGTTCTAAAGTTTCTAGAAGATA
TTAAATTATGTATAAAAGTAATTGCGACTCGTGCAAATAGCGAAATGGAA
ATCTTGATGCCGGGATATACGCACCTTCAACAAGCTCAACCGATTCGATG
GAGCCATTGGTTAATGAGCTATGCAAGTTCTTTGAAACGAGATTATTCTC
GTTTTTATGATCTCATGAAACGGATTGATATTTGCCCTTTAGGGAGTGGT
GCCCTAGCAGGCAATCCGTTTAAAATTGACAGAAAATCTTTAGCTAAAGA
ACTGAATTTTACCGATGTCAGCATGAATAGTTTGGACGGAGTCAGTTCTC
GAGATTATATAGTTGAGCTGCAATCTTGTGCGACAATTTGCGCAATAAAT
CTCAGCAGATTGGCAGAAGATTTAATTATTTATAGCACCAAAGAATTTTC
TTTCGTTCGTATATCCGATGCATACAGTACCGGAAGTAGTCTAATGCCCC
AAAAAAAGAATCCAGACAGTTTGGAGCTAATTCGTGGAAAATGCGGACGA
ATAGCTGGTCAGATGATCGGCTTCGCAATTACACTGAAAGGAACACCAAG
TACGTATAACAAGGACTTTCAAGAGGATAAAGAGAGTTTATTTGATATTT
GTGATACCATGACATCATTGATTAAAATTGCAACAGGAGTATTAGCAACT
CTTGAAGTAAGCAAAACTAAATGTTATGATGCTCTTAGTCCGGATATGTT
GGCAACCGATATTGCGTATTACTTAGTTCGCAAAGGAGTTCCGTTTAGAG
ATGCTCATGGAATTTCCGGTAAATGTGTAGCATTGTCTGAGAAACTCGGC
TGTTCTATTTCTAGCCTAACATTAGGGCAATTGGGATCAATTTGTCATTT
ATTTGAGGATGACGTTCTGAAAATGTGGAATTATGAGAATAGCGTTGAGC
AATACTCTGTGCTTGGGGGAACCAGTTTTGAAAGTGTTGAATATCAAATT
AAAGAAATGCTAAAATGGGTTGATTAAAAATTAATATTTTATGATTTTAC
TAGTAACTTTTGTAATTTGTCTTTGTTTAATGTTTCATTTATGTTAGTTT
TAATTTGATAATATAGTGGATTATTTATTTTGTTATTTTACTTTTAG

protein sequence of SMED30030034-orf-1

>SMED30030034-orf-1 ID=SMED30030034-orf-1|Name=SMED30030034-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=459bp
MTEHSLWGGRFSGKVDPIMEAFNASIKFDKRLWREDIDGSKAYANAIYKV
NLLTVEEKNKMIAGLDQIKEEWENDKFILNEQDEDIHTANERRLKELIGP
TGGKLHTGRSRNDQVATDTRLWCRQWVLKFLEDIKLCIKVIATRANSEME
ILMPGYTHLQQAQPIRWSHWLMSYASSLKRDYSRFYDLMKRIDICPLGSG
ALAGNPFKIDRKSLAKELNFTDVSMNSLDGVSSRDYIVELQSCATICAIN
LSRLAEDLIIYSTKEFSFVRISDAYSTGSSLMPQKKNPDSLELIRGKCGR
IAGQMIGFAITLKGTPSTYNKDFQEDKESLFDICDTMTSLIKIATGVLAT
LEVSKTKCYDALSPDMLATDIAYYLVRKGVPFRDAHGISGKCVALSEKLG
CSISSLTLGQLGSICHLFEDDVLKMWNYENSVEQYSVLGGTSFESVEYQI
KEMLKWVD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000035	Category 3 cell
PLANA:0002032	epidermal cell
PLANA:0002075	pigment cell
PLANA:0002111	X2 cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR009049	Argininosuccinate_lyase
IPR000362	Fumarate_lyase_fam
IPR029419	Arg_succ_lyase_C
IPR024083	Fumarase/histidase_N
IPR022761	Fumarate_lyase_N
IPR020557	Fumarate_lyase_CS
IPR008948	L-Aspartase-like

Vocabulary: **molecular function**
Term	Definition
GO:0003824	catalytic activity
GO:0004056	argininosuccinate lyase activity
GO:0016829	lyase activity

Vocabulary: **biological process**
Term	Definition
GO:0000050	urea cycle
GO:0006526	arginine biosynthetic process
GO:0008652	cellular amino acid biosynthetic process
GO:0042450	arginine biosynthetic process via ornithine

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 55..75
None	No IPR available	PRINTS	PR00145	ARGSUCLYASE	coord: 278..294 score: 81.62 coord: 196..212 score: 62.79 coord: 104..126 score: 71.61 coord: 313..332 score: 67.97 coord: 145..165 score: 56.53 coord: 234..258 score: 44.29
None	No IPR available	GENE3D	G3DSA:1.20.200.10		coord: 122..450 e-value: 2.9E-182 score: 608.2
None	No IPR available	GENE3D	G3DSA:1.10.40.30		coord: 363..434 e-value: 2.9E-182 score: 608.2
None	No IPR available	PANTHER	PTHR43814:SF1	ARGININOSUCCINATE LYASE	coord: 3..455
IPR000362	Fumarate lyase family	PRINTS	PR00149	FUMRATELYASE	coord: 105..123 score: 39.31 coord: 234..261 score: 29.27 coord: 150..168 score: 42.07 coord: 278..294 score: 61.46
IPR029419	Argininosuccinate lyase, C-terminal	PFAM	PF14698	ASL_C2	coord: 366..433 e-value: 1.5E-20 score: 73.7
IPR022761	Fumarate lyase, N-terminal	PFAM	PF00206	Lyase_1	coord: 9..303 e-value: 1.8E-96 score: 323.2
IPR024083	Fumarase/histidase, N-terminal	GENE3D	G3DSA:1.10.275.10		coord: 28..232 e-value: 2.9E-182 score: 608.2
IPR009049	Argininosuccinate lyase	TIGRFAM	TIGR00838	TIGR00838	coord: 6..453 e-value: 5.3E-178 score: 590.6
IPR009049	Argininosuccinate lyase	PANTHER	PTHR43814	FAMILY NOT NAMED	coord: 3..455
IPR009049	Argininosuccinate lyase	CDD	cd01359	Argininosuccinate_lyase	coord: 25..457 e-value: 0.0 score: 644.215
IPR020557	Fumarate lyase, conserved site	PROSITE	PS00163	FUMARATE_LYASES	coord: 278..287
IPR008948	L-Aspartase-like	SUPERFAMILY	SSF48557	L-aspartase-like	coord: 9..457