Pleckstrin homology and RhoGEF domain containing G6

Overview
NamePleckstrin homology and RhoGEF domain containing G6
Smed IDSMED30030017
Length (bp)2150
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Pleckstrin homology and RhoGEF domain containing G6 (SMED30030017) t-SNE clustered cells

Violin plots show distribution of expression levels for Pleckstrin homology and RhoGEF domain containing G6 (SMED30030017) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Pleckstrin homology and RhoGEF domain containing G6 (SMED30030017) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Pleckstrin homology and RhoGEF domain containing G6 (SMED30030017) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30030017

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30030017h1SMcG0009284 SmedASXL_005609SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
muscle cellSMED30030017h1SMcG0009284 dd_Smed_v4_15386_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Human
Match: PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6 [Source:HGNC Symbol;Acc:HGNC:25562])

HSP 1 Score: 132.109 bits (331), Expect = 3.464e-31
Identity = 86/359 (23.96%), Postives = 167/359 (46.52%), Query Frame = 1 
Query:  463 EMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGF----PTIEEYIKAIFPIPPYPVFNMTCPM-QVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFST 1521
            EM QE+ H+Q                 +WEL+T+E++Y++++  +       L+++++     ++   ++FGN+  + R++  FW E +    +  +      D   + SGF  F ++F PY  YC+ +     Y  + +  +  F  F++WC     S R  L   +  P QR+T+Y L L  ++K   +      L+  I  V+ F+ +IN  ++  E    L      +  +    P  +E  K +    P+   ++T PM  V SE+    R L+ +  +R+K+     + V + LF+D+L+  KP +K  + +  ++  P+ L++LV       + +  S  L  + +FQC S+
Sbjct:  122 EMSQELCHQQE---------------ALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLR---PFSTLDLTSPMLGVASEH---TRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAK--VIRPPLMLEKLVCQP----LRDPNSFLLIHLTEFQCVSS 453
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Human
Match: PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6 [Source:HGNC Symbol;Acc:HGNC:25562])

HSP 1 Score: 132.109 bits (331), Expect = 3.485e-31
Identity = 86/359 (23.96%), Postives = 167/359 (46.52%), Query Frame = 1 
Query:  463 EMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGF----PTIEEYIKAIFPIPPYPVFNMTCPM-QVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFST 1521
            EM QE+ H+Q                 +WEL+T+E++Y++++  +       L+++++     ++   ++FGN+  + R++  FW E +    +  +      D   + SGF  F ++F PY  YC+ +     Y  + +  +  F  F++WC     S R  L   +  P QR+T+Y L L  ++K   +      L+  I  V+ F+ +IN  ++  E    L      +  +    P  +E  K +    P+   ++T PM  V SE+    R L+ +  +R+K+     + V + LF+D+L+  KP +K  + +  ++  P+ L++LV       + +  S  L  + +FQC S+
Sbjct:  154 EMSQELCHQQE---------------ALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLR---PFSTLDLTSPMLGVASEH---TRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAK--VIRPPLMLEKLVCQP----LRDPNSFLLIHLTEFQCVSS 485
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Human
Match: PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6 [Source:HGNC Symbol;Acc:HGNC:25562])

HSP 1 Score: 132.109 bits (331), Expect = 3.485e-31
Identity = 86/359 (23.96%), Postives = 167/359 (46.52%), Query Frame = 1 
Query:  463 EMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGF----PTIEEYIKAIFPIPPYPVFNMTCPM-QVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFST 1521
            EM QE+ H+Q                 +WEL+T+E++Y++++  +       L+++++     ++   ++FGN+  + R++  FW E +    +  +      D   + SGF  F ++F PY  YC+ +     Y  + +  +  F  F++WC     S R  L   +  P QR+T+Y L L  ++K   +      L+  I  V+ F+ +IN  ++  E    L      +  +    P  +E  K +    P+   ++T PM  V SE+    R L+ +  +R+K+     + V + LF+D+L+  KP +K  + +  ++  P+ L++LV       + +  S  L  + +FQC S+
Sbjct:  154 EMSQELCHQQE---------------ALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLR---PFSTLDLTSPMLGVASEH---TRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAK--VIRPPLMLEKLVCQP----LRDPNSFLLIHLTEFQCVSS 485
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Human
Match: PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6 [Source:HGNC Symbol;Acc:HGNC:25562])

HSP 1 Score: 124.79 bits (312), Expect = 1.382e-29
Identity = 78/329 (23.71%), Postives = 155/329 (47.11%), Query Frame = 1 
Query:  463 EMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPM-QVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLV 1440
            EM QE+ H+Q                 +WEL+T+E++Y++++  +       L+++++     ++   ++FGN+  + R++  FW E +    +  +      D   + SGF  F ++F PY  YC+ +     Y  + +  +  F  F++WC     S R  L   +  P QR+T+Y L L  ++K   +      L+  I  V+ F+ +IN  ++  E    L      +  +  +E     +   + P+   ++T PM  V SE+    R L+ +  +R+K+     + V + LF+D+L+  KP +K  + +  ++  P+ L++LV
Sbjct:  154 EMSQELCHQQE---------------ALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEH---TRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAK--VIRPPLMLEKLV 462
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Human
Match: PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5 [Source:HGNC Symbol;Acc:HGNC:29105])

HSP 1 Score: 118.242 bits (295), Expect = 1.031e-26
Identity = 76/331 (22.96%), Postives = 155/331 (46.83%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E  Y++++  I+   L  L++++++    +++   +F NI E+ + +   W   M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  +      +   I  V++F++++N  ++ ++   +L    S +  +  +E     +   +  +   ++T P+   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK ++ R  ++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  417 AVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGAS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTR--VIRPPLLVDKIVCRE----LRDPGSFLLIYLNEFHSAVGAY 739
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Celegans
Match: rhgf-2 (RHo Guanine nucleotide exchange Factor [Source:UniProtKB/TrEMBL;Acc:Q22354])

HSP 1 Score: 87.4261 bits (215), Expect = 1.727e-17
Identity = 78/359 (21.73%), Postives = 175/359 (48.75%), Query Frame = 1 
Query:  472 QEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNV-IFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGL-DTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTI-EEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKT-ISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            +E+ H  N ES ++  I+ +++  IWE++T+E  Y+K + ++       L D++   F   ++   +F N + +F  N    W + +E +    +      D+ ++ +GF +       Y ++ +  S   ++I K   ES+ FR F+ W    ++ +R  L DTF ++P QRLTRY+L L  ++K  +D++E   +S  +   +     +NK +   ++ + L      + G   + ++ ++ +F +   P+ N+   M +    +   R LI++  LR+++  + +   V  ++FTD+ +  + + + ++ RL++L  PI + +++ +       +    +L  +  F     +Y +
Sbjct:  261 REIVH--NHESLSDKSIKQQEA--IWEIVTTEFRYIKLLRYLSNLSF-YLTDLQNCGFLKDIENRLVFFNFVTLFNVNYDSLWLQSIEPILAKSRETGEPLDVNYLQNGFRDIENWSRCYTNFHLAHSDSLKHIQKKLKESENFRDFVTWAEAQENLDRQKLIDTF-SVPMQRLTRYNLLLKAVLKVTTDENEREMISNLVDCAESATAQLNKELNNNDLRAMLGDVMRTIEGPDYVDQDELERLFNL-KLPL-NLGDFMPLLHPRKPTHRTLIYRGDLRMQEGKKGSKADVHCIIFTDMFLICRKV-QGKKDRLKILKPPIHMGKMMFH----YFADQNGFYLVHLTDFHTAQALYSM 606
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Celegans
Match: rhgf-2 (RHo Guanine nucleotide exchange Factor [Source:UniProtKB/TrEMBL;Acc:Q22354])

HSP 1 Score: 87.4261 bits (215), Expect = 1.727e-17
Identity = 78/359 (21.73%), Postives = 175/359 (48.75%), Query Frame = 1 
Query:  472 QEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNV-IFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGL-DTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTI-EEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKT-ISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            +E+ H  N ES ++  I+ +++  IWE++T+E  Y+K + ++       L D++   F   ++   +F N + +F  N    W + +E +    +      D+ ++ +GF +       Y ++ +  S   ++I K   ES+ FR F+ W    ++ +R  L DTF ++P QRLTRY+L L  ++K  +D++E   +S  +   +     +NK +   ++ + L      + G   + ++ ++ +F +   P+ N+   M +    +   R LI++  LR+++  + +   V  ++FTD+ +  + + + ++ RL++L  PI + +++ +       +    +L  +  F     +Y +
Sbjct:  261 REIVH--NHESLSDKSIKQQEA--IWEIVTTEFRYIKLLRYLSNLSF-YLTDLQNCGFLKDIENRLVFFNFVTLFNVNYDSLWLQSIEPILAKSRETGEPLDVNYLQNGFRDIENWSRCYTNFHLAHSDSLKHIQKKLKESENFRDFVTWAEAQENLDRQKLIDTF-SVPMQRLTRYNLLLKAVLKVTTDENEREMISNLVDCAESATAQLNKELNNNDLRAMLGDVMRTIEGPDYVDQDELERLFNL-KLPL-NLGDFMPLLHPRKPTHRTLIYRGDLRMQEGKKGSKADVHCIIFTDMFLICRKV-QGKKDRLKILKPPIHMGKMMFH----YFADQNGFYLVHLTDFHTAQALYSM 606
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Celegans
Match: rhgf-2 (RHo Guanine nucleotide exchange Factor [Source:UniProtKB/TrEMBL;Acc:Q22354])

HSP 1 Score: 87.0409 bits (214), Expect = 1.962e-17
Identity = 78/359 (21.73%), Postives = 175/359 (48.75%), Query Frame = 1 
Query:  472 QEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNV-IFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGL-DTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTI-EEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKT-ISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            +E+ H  N ES ++  I+ +++  IWE++T+E  Y+K + ++       L D++   F   ++   +F N + +F  N    W + +E +    +      D+ ++ +GF +       Y ++ +  S   ++I K   ES+ FR F+ W    ++ +R  L DTF ++P QRLTRY+L L  ++K  +D++E   +S  +   +     +NK +   ++ + L      + G   + ++ ++ +F +   P+ N+   M +    +   R LI++  LR+++  + +   V  ++FTD+ +  + + + ++ RL++L  PI + +++ +       +    +L  +  F     +Y +
Sbjct:  116 REIVH--NHESLSDKSIKQQEA--IWEIVTTEFRYIKLLRYLSNLSF-YLTDLQNCGFLKDIENRLVFFNFVTLFNVNYDSLWLQSIEPILAKSRETGEPLDVNYLQNGFRDIENWSRCYTNFHLAHSDSLKHIQKKLKESENFRDFVTWAEAQENLDRQKLIDTF-SVPMQRLTRYNLLLKAVLKVTTDENEREMISNLVDCAESATAQLNKELNNNDLRAMLGDVMRTIEGPDYVDQDELERLFNL-KLPL-NLGDFMPLLHPRKPTHRTLIYRGDLRMQEGKKGSKADVHCIIFTDMFLICRKV-QGKKDRLKILKPPIHMGKMMFH----YFADQNGFYLVHLTDFHTAQALYSM 461
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Celegans
Match: rhgf-2 (RHo Guanine nucleotide exchange Factor [Source:UniProtKB/TrEMBL;Acc:Q22354])

HSP 1 Score: 87.0409 bits (214), Expect = 2.858e-17
Identity = 79/359 (22.01%), Postives = 176/359 (49.03%), Query Frame = 1 
Query:  472 QEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPK-LDVFSIFGNILEVFRSNV-IFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGL-DTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTI-EEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKT-ISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            +E+ H  N ES ++  I+ +++  IWE++T+E  Y+K + ++       L D++   F K ++   +F N + +F  N    W + +E +    +      D+ ++ +GF +       Y ++ +  S   ++I K   ES+ FR F+ W    ++ +R  L DTF ++P QRLTRY+L L  ++K  +D++E   +S  +   +     +NK +   ++ + L      + G   + ++ ++ +F +   P+ N+   M +    +   R LI++  LR+++  + +   V  ++FTD+ +  + + + ++ RL++L  PI + +++ +       +    +L  +  F     +Y +
Sbjct:  403 REIVH--NHESLSDKSIKQQEA--IWEIVTTEFRYIKLLRYLSNLSF-YLTDLQNCGFLKDIENRLVFFNFVTLFNVNYDSLWLQSIEPILAKSRETGEPLDVNYLQNGFRDIENWSRCYTNFHLAHSDSLKHIQKKLKESENFRDFVTWAEAQENLDRQKLIDTF-SVPMQRLTRYNLLLKAVLKVTTDENEREMISNLVDCAESATAQLNKELNNNDLRAMLGDVMRTIEGPDYVDQDELERLFNL-KLPL-NLGDFMPLLHPRKPTHRTLIYRGDLRMQEGKKGSKADVHCIIFTDMFLICRKV-QGKKDRLKILKPPIHMGKMMFH----YFADQNGFYLVHLTDFHTAQALYSM 748
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Celegans
Match: prhg-1 (pep chromosome:WBcel235:I:912415:919137:-1 gene:WBGene00022391.1 transcript:Y95B8A.12b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:prhg-1)

HSP 1 Score: 70.8626 bits (172), Expect = 1.788e-12
Identity = 96/439 (21.87%), Postives = 185/439 (42.14%), Query Frame = 1 
Query:  235 LLNPFQKRSNDDSLFFIEKQEPFPKRPAKLLQS--TKSKTSMTRNNCESITEILQSYSAERVSNPIDSAYSFIDELTTEMP---QEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIV----KTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILK-NCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPPYPVFNMTCPMQ-VKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAK-------------PIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQS 1479
            LL   Q+ +     F+ E  EP   R   +L+     S  +  R   + +   L++     + +         DEL   +P   +EMF    T +   SK +  ++  +WEL  +E+V+L +  F++    K PL            + D+  +FGN+ ++ R +  F   ++  +  + K N D    +  +   F+        Y++YC+N  A  EY+     + + F  F   C   +   RL L+  +  P QR+TR  + L  I K   +++   ++ + I  + + + +I+ S++      +L+  Q+ +  +P I +     + +P +    +    Q  ++   +  R LIH+  L L +  R T+ +   LF D+ +  K             PI K++   +Q    P+ LD  V  D+ +   NDQ+
Sbjct:   85 LLADLQRATIASQAFYAEASEPQKNRSPWILKRLYEWSGRAKRREIIKHVQAALETSKDHEIED---------DELEKLLPVSFEEMFMGDETTTIPSSKHKYLQA--VWELFHTELVFLYRQLFVLRDVYKEPLKRCQVEGCLLLVEPDL--LFGNLDQLCRISRTFCQSFLSLLSTVDKENWDCTQLVVDLFERFSKGPSTISAYQAYCINYKATMEYLGSIRQKEERFTEFERICLADERCFRLQLEDLLIAPLQRITRLPILLREIHKRSEEEESKGKVEKVIDTMTESLRSIDDSVQWLHNFERLQQLQTQVV-WPNISDLEPKSY-VPDF--LRVALSRQFCENLLAHPRRKLIHEGPLELVENGR-TVDMYAFLFNDMFVLTKTKKCASKLKVKGVPIGKSEHYIVQ--RQPVPLDSCVFCDADS---NDQA 500
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Fly
Match: CG42674 (gene:FBgn0261556 transcript:FBtr0332699)

HSP 1 Score: 119.783 bits (299), Expect = 1.588e-27
Identity = 97/395 (24.56%), Postives = 179/395 (45.32%), Query Frame = 1 
Query:  376 ITEILQSYSAERVSNPIDS-AYSFIDELTTEMPQEMFHRQ-----NTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI--PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            + E+L SY+   V    DS ++   D + +    +  H+      N++S +ES+++ + +  IWEL+T+E+ Y+  +  +    L  L  +++      +D   +F N+  V  +N+ FWT ++  +                  GF +F+  F PYK YC   S    Y  +    +  F  +L WC +    NRL L   +  P QRLT+YSL L  I K  SD +EI  +   +  V+ FV ++N  + +++   +L+     +  +  ++   + +  +      +F++  PM+    Y   VR L  +   + K    K+  V   L TDLL+  K I K     L+++  P   DQL++      +  + ++    +N+FQ  +T + L
Sbjct:  190 LCELLNSYAKNGVPQRPDSMSFDHPDLVNSLAYLQYMHKSWRDFVNSDSMSESEVKIQTA--IWELVTTEVYYIHALQTVTDLFLACLEAVQEEGLLIDVDQARLFSNVRAVCEANIKFWTLWLYPMVAHSAITHEPLRCAFFQEGFLSFASIFAPYKIYCAEQSTCQFYCKELNHNNALFTSYLAWCESQKMCNRLRLADIVVRPMQRLTKYSLLLAAIKKHMSDVEEIEAIDVMMHSVENFVGSVNNHLTMRQENERLKGVMVRIESYDVVDTNNEVLDKMIKQNSQMFDLCAPMRGCPAY--HVRHLFMEGDHKFKDNLGKS-DVHCFLLTDLLLVCKTIAKRGLGALKVIRQPYLTDQLIV-----QLAPNNTLNCVYLNEFQVATTAFTL 574
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Fly
Match: CG42674 (gene:FBgn0261556 transcript:FBtr0332698)

HSP 1 Score: 117.857 bits (294), Expect = 9.989e-27
Identity = 97/395 (24.56%), Postives = 179/395 (45.32%), Query Frame = 1 
Query:  376 ITEILQSYSAERVSNPIDS-AYSFIDELTTEMPQEMFHRQ-----NTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI--PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            + E+L SY+   V    DS ++   D + +    +  H+      N++S +ES+++ + +  IWEL+T+E+ Y+  +  +    L  L  +++      +D   +F N+  V  +N+ FWT ++  +                  GF +F+  F PYK YC   S    Y  +    +  F  +L WC +    NRL L   +  P QRLT+YSL L  I K  SD +EI  +   +  V+ FV ++N  + +++   +L+     +  +  ++   + +  +      +F++  PM+    Y   VR L  +   + K    K+  V   L TDLL+  K I K     L+++  P   DQL++      +  + ++    +N+FQ  +T + L
Sbjct:  754 LCELLNSYAKNGVPQRPDSMSFDHPDLVNSLAYLQYMHKSWRDFVNSDSMSESEVKIQTA--IWELVTTEVYYIHALQTVTDLFLACLEAVQEEGLLIDVDQARLFSNVRAVCEANIKFWTLWLYPMVAHSAITHEPLRCAFFQEGFLSFASIFAPYKIYCAEQSTCQFYCKELNHNNALFTSYLAWCESQKMCNRLRLADIVVRPMQRLTKYSLLLAAIKKHMSDVEEIEAIDVMMHSVENFVGSVNNHLTMRQENERLKGVMVRIESYDVVDTNNEVLDKMIKQNSQMFDLCAPMRGCPAY--HVRHLFMEGDHKFKDNLGKS-DVHCFLLTDLLLVCKTIAKRGLGALKVIRQPYLTDQLIV-----QLAPNNTLNCVYLNEFQVATTAFTL 1138
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Fly
Match: CG42674 (gene:FBgn0261556 transcript:FBtr0302716)

HSP 1 Score: 117.857 bits (294), Expect = 9.989e-27
Identity = 97/395 (24.56%), Postives = 179/395 (45.32%), Query Frame = 1 
Query:  376 ITEILQSYSAERVSNPIDS-AYSFIDELTTEMPQEMFHRQ-----NTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI--PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            + E+L SY+   V    DS ++   D + +    +  H+      N++S +ES+++ + +  IWEL+T+E+ Y+  +  +    L  L  +++      +D   +F N+  V  +N+ FWT ++  +                  GF +F+  F PYK YC   S    Y  +    +  F  +L WC +    NRL L   +  P QRLT+YSL L  I K  SD +EI  +   +  V+ FV ++N  + +++   +L+     +  +  ++   + +  +      +F++  PM+    Y   VR L  +   + K    K+  V   L TDLL+  K I K     L+++  P   DQL++      +  + ++    +N+FQ  +T + L
Sbjct:  754 LCELLNSYAKNGVPQRPDSMSFDHPDLVNSLAYLQYMHKSWRDFVNSDSMSESEVKIQTA--IWELVTTEVYYIHALQTVTDLFLACLEAVQEEGLLIDVDQARLFSNVRAVCEANIKFWTLWLYPMVAHSAITHEPLRCAFFQEGFLSFASIFAPYKIYCAEQSTCQFYCKELNHNNALFTSYLAWCESQKMCNRLRLADIVVRPMQRLTKYSLLLAAIKKHMSDVEEIEAIDVMMHSVENFVGSVNNHLTMRQENERLKGVMVRIESYDVVDTNNEVLDKMIKQNSQMFDLCAPMRGCPAY--HVRHLFMEGDHKFKDNLGKS-DVHCFLLTDLLLVCKTIAKRGLGALKVIRQPYLTDQLIV-----QLAPNNTLNCVYLNEFQVATTAFTL 1138
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Fly
Match: CG42674 (gene:FBgn0261556 transcript:FBtr0302715)

HSP 1 Score: 117.087 bits (292), Expect = 1.761e-26
Identity = 97/395 (24.56%), Postives = 179/395 (45.32%), Query Frame = 1 
Query:  376 ITEILQSYSAERVSNPIDS-AYSFIDELTTEMPQEMFHRQ-----NTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI--PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            + E+L SY+   V    DS ++   D + +    +  H+      N++S +ES+++ + +  IWEL+T+E+ Y+  +  +    L  L  +++      +D   +F N+  V  +N+ FWT ++  +                  GF +F+  F PYK YC   S    Y  +    +  F  +L WC +    NRL L   +  P QRLT+YSL L  I K  SD +EI  +   +  V+ FV ++N  + +++   +L+     +  +  ++   + +  +      +F++  PM+    Y   VR L  +   + K    K+  V   L TDLL+  K I K     L+++  P   DQL++      +  + ++    +N+FQ  +T + L
Sbjct:  787 LCELLNSYAKNGVPQRPDSMSFDHPDLVNSLAYLQYMHKSWRDFVNSDSMSESEVKIQTA--IWELVTTEVYYIHALQTVTDLFLACLEAVQEEGLLIDVDQARLFSNVRAVCEANIKFWTLWLYPMVAHSAITHEPLRCAFFQEGFLSFASIFAPYKIYCAEQSTCQFYCKELNHNNALFTSYLAWCESQKMCNRLRLADIVVRPMQRLTKYSLLLAAIKKHMSDVEEIEAIDVMMHSVENFVGSVNNHLTMRQENERLKGVMVRIESYDVVDTNNEVLDKMIKQNSQMFDLCAPMRGCPAY--HVRHLFMEGDHKFKDNLGKS-DVHCFLLTDLLLVCKTIAKRGLGALKVIRQPYLTDQLIV-----QLAPNNTLNCVYLNEFQVATTAFTL 1171
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Fly
Match: CG42674 (gene:FBgn0261556 transcript:FBtr0302713)

HSP 1 Score: 116.316 bits (290), Expect = 2.797e-26
Identity = 97/395 (24.56%), Postives = 179/395 (45.32%), Query Frame = 1 
Query:  376 ITEILQSYSAERVSNPIDS-AYSFIDELTTEMPQEMFHRQ-----NTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI--PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL 1533
            + E+L SY+   V    DS ++   D + +    +  H+      N++S +ES+++ + +  IWEL+T+E+ Y+  +  +    L  L  +++      +D   +F N+  V  +N+ FWT ++  +                  GF +F+  F PYK YC   S    Y  +    +  F  +L WC +    NRL L   +  P QRLT+YSL L  I K  SD +EI  +   +  V+ FV ++N  + +++   +L+     +  +  ++   + +  +      +F++  PM+    Y   VR L  +   + K    K+  V   L TDLL+  K I K     L+++  P   DQL++      +  + ++    +N+FQ  +T + L
Sbjct:  787 LCELLNSYAKNGVPQRPDSMSFDHPDLVNSLAYLQYMHKSWRDFVNSDSMSESEVKIQTA--IWELVTTEVYYIHALQTVTDLFLACLEAVQEEGLLIDVDQARLFSNVRAVCEANIKFWTLWLYPMVAHSAITHEPLRCAFFQEGFLSFASIFAPYKIYCAEQSTCQFYCKELNHNNALFTSYLAWCESQKMCNRLRLADIVVRPMQRLTKYSLLLAAIKKHMSDVEEIEAIDVMMHSVENFVGSVNNHLTMRQENERLKGVMVRIESYDVVDTNNEVLDKMIKQNSQMFDLCAPMRGCPAY--HVRHLFMEGDHKFKDNLGKS-DVHCFLLTDLLLVCKTIAKRGLGALKVIRQPYLTDQLIV-----QLAPNNTLNCVYLNEFQVATTAFTL 1171
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Zebrafish
Match: plekhg5a (pleckstrin homology domain containing, family G (with RhoGef domain) member 5a [Source:ZFIN;Acc:ZDB-GENE-060503-766])

HSP 1 Score: 134.035 bits (336), Expect = 7.788e-32
Identity = 80/331 (24.17%), Postives = 163/331 (49.24%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++H I    L  L++++++    +++   +F NI ++ + +   WTE M    +  +    + +   +  GF+ F  +F PY  YCM      EY+     +++ FR+++ W       NRL L   +  P QRLT+Y L L  ++K+  D      +++ ++ V+ F+N+++  ++ +E   KL      +  +  +E   + +  I   Y  F++  P  V      E R L+ +  L++K+     + V   LFTD+L+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F C    Y
Sbjct:  340 AIWELLQTESDYIKKLHVITDLFLCGLLNLQESGLLTEVEPTRLFSNIQDIVQLHSSLWTEVMLPALEKARQKRTMLNPTELHQGFSTFGFRFKPYIRYCMEEEGCMEYMRTLLKDNELFRIYVTWAETHKQCNRLKLTDMLVKPHQRLTKYPLLLKSVLKKTDDPPTREAINRMVAAVECFINSVDSQMRHREEKQKLAAIAGRIEAYEAVEGASEEVERILKEYNNFDLMAP--VMGAPPEETRQLLLEGALKMKEGKESRMDVYCFLFTDVLLITKPVKRVE--KVKVIRQPLVIHNVVCRE----LKDPGSFLLIYLNEFGCAVASY 662
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Zebrafish
Match: plekhg5a (pleckstrin homology domain containing, family G (with RhoGef domain) member 5a [Source:ZFIN;Acc:ZDB-GENE-060503-766])

HSP 1 Score: 134.035 bits (336), Expect = 7.788e-32
Identity = 80/331 (24.17%), Postives = 163/331 (49.24%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++H I    L  L++++++    +++   +F NI ++ + +   WTE M    +  +    + +   +  GF+ F  +F PY  YCM      EY+     +++ FR+++ W       NRL L   +  P QRLT+Y L L  ++K+  D      +++ ++ V+ F+N+++  ++ +E   KL      +  +  +E   + +  I   Y  F++  P  V      E R L+ +  L++K+     + V   LFTD+L+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F C    Y
Sbjct:  340 AIWELLQTESDYIKKLHVITDLFLCGLLNLQESGLLTEVEPTRLFSNIQDIVQLHSSLWTEVMLPALEKARQKRTMLNPTELHQGFSTFGFRFKPYIRYCMEEEGCMEYMRTLLKDNELFRIYVTWAETHKQCNRLKLTDMLVKPHQRLTKYPLLLKSVLKKTDDPPTREAINRMVAAVECFINSVDSQMRHREEKQKLAAIAGRIEAYEAVEGASEEVERILKEYNNFDLMAP--VMGAPPEETRQLLLEGALKMKEGKESRMDVYCFLFTDVLLITKPVKRVE--KVKVIRQPLVIHNVVCRE----LKDPGSFLLIYLNEFGCAVASY 662
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Zebrafish
Match: plekhg5a (pleckstrin homology domain containing, family G (with RhoGef domain) member 5a [Source:ZFIN;Acc:ZDB-GENE-060503-766])

HSP 1 Score: 134.035 bits (336), Expect = 7.788e-32
Identity = 80/331 (24.17%), Postives = 163/331 (49.24%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++H I    L  L++++++    +++   +F NI ++ + +   WTE M    +  +    + +   +  GF+ F  +F PY  YCM      EY+     +++ FR+++ W       NRL L   +  P QRLT+Y L L  ++K+  D      +++ ++ V+ F+N+++  ++ +E   KL      +  +  +E   + +  I   Y  F++  P  V      E R L+ +  L++K+     + V   LFTD+L+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F C    Y
Sbjct:  340 AIWELLQTESDYIKKLHVITDLFLCGLLNLQESGLLTEVEPTRLFSNIQDIVQLHSSLWTEVMLPALEKARQKRTMLNPTELHQGFSTFGFRFKPYIRYCMEEEGCMEYMRTLLKDNELFRIYVTWAETHKQCNRLKLTDMLVKPHQRLTKYPLLLKSVLKKTDDPPTREAINRMVAAVECFINSVDSQMRHREEKQKLAAIAGRIEAYEAVEGASEEVERILKEYNNFDLMAP--VMGAPPEETRQLLLEGALKMKEGKESRMDVYCFLFTDVLLITKPVKRVE--KVKVIRQPLVIHNVVCRE----LKDPGSFLLIYLNEFGCAVASY 662
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Zebrafish
Match: plekhg5a (pleckstrin homology domain containing, family G (with RhoGef domain) member 5a [Source:ZFIN;Acc:ZDB-GENE-060503-766])

HSP 1 Score: 133.65 bits (335), Expect = 1.002e-31
Identity = 80/331 (24.17%), Postives = 163/331 (49.24%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++H I    L  L++++++    +++   +F NI ++ + +   WTE M    +  +    + +   +  GF+ F  +F PY  YCM      EY+     +++ FR+++ W       NRL L   +  P QRLT+Y L L  ++K+  D      +++ ++ V+ F+N+++  ++ +E   KL      +  +  +E   + +  I   Y  F++  P  V      E R L+ +  L++K+     + V   LFTD+L+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F C    Y
Sbjct:  388 AIWELLQTESDYIKKLHVITDLFLCGLLNLQESGLLTEVEPTRLFSNIQDIVQLHSSLWTEVMLPALEKARQKRTMLNPTELHQGFSTFGFRFKPYIRYCMEEEGCMEYMRTLLKDNELFRIYVTWAETHKQCNRLKLTDMLVKPHQRLTKYPLLLKSVLKKTDDPPTREAINRMVAAVECFINSVDSQMRHREEKQKLAAIAGRIEAYEAVEGASEEVERILKEYNNFDLMAP--VMGAPPEETRQLLLEGALKMKEGKESRMDVYCFLFTDVLLITKPVKRVE--KVKVIRQPLVIHNVVCRE----LKDPGSFLLIYLNEFGCAVASY 710
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Zebrafish
Match: plekhg5a (pleckstrin homology domain containing, family G (with RhoGef domain) member 5a [Source:ZFIN;Acc:ZDB-GENE-060503-766])

HSP 1 Score: 133.65 bits (335), Expect = 1.090e-31
Identity = 80/331 (24.17%), Postives = 163/331 (49.24%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++H I    L  L++++++    +++   +F NI ++ + +   WTE M    +  +    + +   +  GF+ F  +F PY  YCM      EY+     +++ FR+++ W       NRL L   +  P QRLT+Y L L  ++K+  D      +++ ++ V+ F+N+++  ++ +E   KL      +  +  +E   + +  I   Y  F++  P  V      E R L+ +  L++K+     + V   LFTD+L+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F C    Y
Sbjct:  418 AIWELLQTESDYIKKLHVITDLFLCGLLNLQESGLLTEVEPTRLFSNIQDIVQLHSSLWTEVMLPALEKARQKRTMLNPTELHQGFSTFGFRFKPYIRYCMEEEGCMEYMRTLLKDNELFRIYVTWAETHKQCNRLKLTDMLVKPHQRLTKYPLLLKSVLKKTDDPPTREAINRMVAAVECFINSVDSQMRHREEKQKLAAIAGRIEAYEAVEGASEEVERILKEYNNFDLMAP--VMGAPPEETRQLLLEGALKMKEGKESRMDVYCFLFTDVLLITKPVKRVE--KVKVIRQPLVIHNVVCRE----LKDPGSFLLIYLNEFGCAVASY 740
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Xenopus
Match: PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:100496612])

HSP 1 Score: 109.383 bits (272), Expect = 6.174e-24
Identity = 85/349 (24.36%), Postives = 168/349 (48.14%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYE-LSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYF 1578
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ + +       +E   +  K+  N  D +     F  F   F PY  YCM      EY+     +++ F+ ++ W       NRL L   +  P QRLT+Y L L  I+K+ +DD ++ E +   IS V++F+N++N  ++ ++   +L    S +  +  ++     +  I   +   ++T PM   S    + R L+ + +L++K+     + V   LFTDL +  KP+KK +  R +++  P+ +D++V  +    +++  S  L  +N+F+     Y       S  +  ++ F
Sbjct:  361 AIWELLHTEATYIKKLKVITDLFLCCLLNLQESGILCEVEPDKLFSNIQEIIQLHSTVMVPILEKARKT-KSLLNPMDFQKGFR-FKMFESLFKPYIRYCMEEEGCMEYMRNLHRDNELFKSYVTWSEKHKQCNRLKLSDMLVKPHQRLTKYPLLLKSILKK-TDDLQVRESIILMISSVERFINHVNSRMRQRQEQQRLAAIISRIDSYEAVDSSTDEVDKILKEFCRLDLTAPMIGTS--PEDTRQLLLEGSLKMKEGKDSKMDVYCFLFTDLFLITKPVKKAE--RTKVIRQPLLVDKIVCRE----LKDPGSFLLIYLNEFRSAVAAYTFQASGQSLCRGWIEAF 698
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Xenopus
Match: PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:100496612])

HSP 1 Score: 109.383 bits (272), Expect = 6.563e-24
Identity = 85/349 (24.36%), Postives = 168/349 (48.14%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYE-LSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYF 1578
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ + +       +E   +  K+  N  D +     F  F   F PY  YCM      EY+     +++ F+ ++ W       NRL L   +  P QRLT+Y L L  I+K+ +DD ++ E +   IS V++F+N++N  ++ ++   +L    S +  +  ++     +  I   +   ++T PM   S    + R L+ + +L++K+     + V   LFTDL +  KP+KK +  R +++  P+ +D++V  +    +++  S  L  +N+F+     Y       S  +  ++ F
Sbjct:  361 AIWELLHTEATYIKKLKVITDLFLCCLLNLQESGILCEVEPDKLFSNIQEIIQLHSTVMVPILEKARKT-KSLLNPMDFQKGFR-FKMFESLFKPYIRYCMEEEGCMEYMRNLHRDNELFKSYVTWSEKHKQCNRLKLSDMLVKPHQRLTKYPLLLKSILKK-TDDLQVRESIILMISSVERFINHVNSRMRQRQEQQRLAAIISRIDSYEAVDSSTDEVDKILKEFCRLDLTAPMIGTS--PEDTRQLLLEGSLKMKEGKDSKMDVYCFLFTDLFLITKPVKKAE--RTKVIRQPLLVDKIVCRE----LKDPGSFLLIYLNEFRSAVAAYTFQASGQSLCRGWIEAF 698
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Xenopus
Match: PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:100496612])

HSP 1 Score: 109.383 bits (272), Expect = 7.116e-24
Identity = 85/349 (24.36%), Postives = 168/349 (48.14%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYE-LSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYF 1578
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ + +       +E   +  K+  N  D +     F  F   F PY  YCM      EY+     +++ F+ ++ W       NRL L   +  P QRLT+Y L L  I+K+ +DD ++ E +   IS V++F+N++N  ++ ++   +L    S +  +  ++     +  I   +   ++T PM   S    + R L+ + +L++K+     + V   LFTDL +  KP+KK +  R +++  P+ +D++V  +    +++  S  L  +N+F+     Y       S  +  ++ F
Sbjct:  366 AIWELLHTEATYIKKLKVITDLFLCCLLNLQESGILCEVEPDKLFSNIQEIIQLHSTVMVPILEKARKT-KSLLNPMDFQKGFR-FKMFESLFKPYIRYCMEEEGCMEYMRNLHRDNELFKSYVTWSEKHKQCNRLKLSDMLVKPHQRLTKYPLLLKSILKK-TDDLQVRESIILMISSVERFINHVNSRMRQRQEQQRLAAIISRIDSYEAVDSSTDEVDKILKEFCRLDLTAPMIGTS--PEDTRQLLLEGSLKMKEGKDSKMDVYCFLFTDLFLITKPVKKAE--RTKVIRQPLLVDKIVCRE----LKDPGSFLLIYLNEFRSAVAAYTFQASGQSLCRGWIEAF 703
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Xenopus
Match: PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:100496612])

HSP 1 Score: 108.612 bits (270), Expect = 7.260e-24
Identity = 85/349 (24.36%), Postives = 168/349 (48.14%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYE-LSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYF 1578
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ + +       +E   +  K+  N  D +     F  F   F PY  YCM      EY+     +++ F+ ++ W       NRL L   +  P QRLT+Y L L  I+K+ +DD ++ E +   IS V++F+N++N  ++ ++   +L    S +  +  ++     +  I   +   ++T PM   S    + R L+ + +L++K+     + V   LFTDL +  KP+KK +  R +++  P+ +D++V  +    +++  S  L  +N+F+     Y       S  +  ++ F
Sbjct:  377 AIWELLHTEATYIKKLKVITDLFLCCLLNLQESGILCEVEPDKLFSNIQEIIQLHSTVMVPILEKARKT-KSLLNPMDFQKGFR-FKMFESLFKPYIRYCMEEEGCMEYMRNLHRDNELFKSYVTWSEKHKQCNRLKLSDMLVKPHQRLTKYPLLLKSILKK-TDDLQVRESIILMISSVERFINHVNSRMRQRQEQQRLAAIISRIDSYEAVDSSTDEVDKILKEFCRLDLTAPMIGTS--PEDTRQLLLEGSLKMKEGKDSKMDVYCFLFTDLFLITKPVKKAE--RTKVIRQPLLVDKIVCRE----LKDPGSFLLIYLNEFRSAVAAYTFQASGQSLCRGWIEAF 714
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Xenopus
Match: PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:100496612])

HSP 1 Score: 109.383 bits (272), Expect = 7.451e-24
Identity = 85/349 (24.36%), Postives = 168/349 (48.14%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYE-LSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYF 1578
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ + +       +E   +  K+  N  D +     F  F   F PY  YCM      EY+     +++ F+ ++ W       NRL L   +  P QRLT+Y L L  I+K+ +DD ++ E +   IS V++F+N++N  ++ ++   +L    S +  +  ++     +  I   +   ++T PM   S    + R L+ + +L++K+     + V   LFTDL +  KP+KK +  R +++  P+ +D++V  +    +++  S  L  +N+F+     Y       S  +  ++ F
Sbjct:  354 AIWELLHTEATYIKKLKVITDLFLCCLLNLQESGILCEVEPDKLFSNIQEIIQLHSTVMVPILEKARKT-KSLLNPMDFQKGFR-FKMFESLFKPYIRYCMEEEGCMEYMRNLHRDNELFKSYVTWSEKHKQCNRLKLSDMLVKPHQRLTKYPLLLKSILKK-TDDLQVRESIILMISSVERFINHVNSRMRQRQEQQRLAAIISRIDSYEAVDSSTDEVDKILKEFCRLDLTAPMIGTS--PEDTRQLLLEGSLKMKEGKDSKMDVYCFLFTDLFLITKPVKKAE--RTKVIRQPLLVDKIVCRE----LKDPGSFLLIYLNEFRSAVAAYTFQASGQSLCRGWIEAF 691
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Mouse
Match: Plekhg6 (pleckstrin homology domain containing, family G (with RhoGef domain) member 6 [Source:MGI Symbol;Acc:MGI:2682298])

HSP 1 Score: 133.65 bits (335), Expect = 6.747e-32
Identity = 80/333 (24.02%), Postives = 159/333 (47.75%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGF----PTIEEYIKAIFPIPPYPVFNMTCP-MQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFST 1521
             +WEL+T+E++YL+++  +       L+++++     ++   ++FGN+  + R++  FW E ++ + +  +      D   + +GF  F ++F PY  YC+ +     Y  + +  +  F  F++WC     S R  L   +  P QR+T+Y L L  + K   +      L+  I  V+ F+ +IN  ++  E    L      +  +    P+ EE  K +    P+   ++  P + V  EY    R L+ +  +R+K+     + V + LF+D+L+  KP +K    R +++  P+ L++LV       + +  S  L  + +FQC S+
Sbjct:  165 ALWELLTTELIYLRKLKIMTDLLAAGLLNLQRVGLLTEVSAETLFGNVPNLIRAHRRFWEEVLQPILEDTRTSGQPLDPVSLQNGFLTFGQRFQPYVQYCLRVKQTMAYAREQQDTNPLFHTFVQWCEKHKRSGRQTLGDLLIKPHQRITKYPLLLQAVRKRSPEPRAQEALNAMIEAVESFLRHINGQVRQGEEQESLMAVAQRIGPYEVLEPSSEEVEKNLR---PFSTLDLMTPVLGVAPEY---TRQLLLEGPVRVKEGREGKMDVYLFLFSDVLLVTKPQRKAD--RAKVIRPPLMLEKLVCRP----LRDPNSFLLIHLTEFQCVSS 485
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Mouse
Match: Plekhg5 (pleckstrin homology domain containing, family G (with RhoGef domain) member 5 [Source:MGI Symbol;Acc:MGI:2652860])

HSP 1 Score: 120.168 bits (300), Expect = 2.076e-27
Identity = 79/331 (23.87%), Postives = 156/331 (47.13%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E+ Y++++  I    L  L++++++    +++   +F NI E+ + +   W   M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  D      +   IS V++F++++N  ++ ++   +L    S +  +  +E     +   +  +   ++T PM   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK +  R +++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  378 AVWELLHTEVSYIRKLRVITNLFLCCLLNLQESGLLCEVEAERLFSNIPEIAKLHRGLWGSVMVPVLEKARRTRALLQPSDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYVTWAEKHQQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTDDPRTKEAIVTMISSVERFIHHVNTCMRQRQERQRLAGVVSRIDAYEVVEGSNDEVDKLLKEFLHLDLTAPMPGTS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAE--RTKVIRPPLLVDKIVCRE----LRDPGSFLLIYLNEFHSAVGAY 700
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Mouse
Match: Plekhg5 (pleckstrin homology domain containing, family G (with RhoGef domain) member 5 [Source:MGI Symbol;Acc:MGI:2652860])

HSP 1 Score: 120.168 bits (300), Expect = 2.272e-27
Identity = 79/331 (23.87%), Postives = 156/331 (47.13%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E+ Y++++  I    L  L++++++    +++   +F NI E+ + +   W   M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  D      +   IS V++F++++N  ++ ++   +L    S +  +  +E     +   +  +   ++T PM   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK +  R +++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  440 AVWELLHTEVSYIRKLRVITNLFLCCLLNLQESGLLCEVEAERLFSNIPEIAKLHRGLWGSVMVPVLEKARRTRALLQPSDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYVTWAEKHQQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTDDPRTKEAIVTMISSVERFIHHVNTCMRQRQERQRLAGVVSRIDAYEVVEGSNDEVDKLLKEFLHLDLTAPMPGTS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAE--RTKVIRPPLLVDKIVCRE----LRDPGSFLLIYLNEFHSAVGAY 762
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Mouse
Match: Plekhg5 (pleckstrin homology domain containing, family G (with RhoGef domain) member 5 [Source:MGI Symbol;Acc:MGI:2652860])

HSP 1 Score: 119.783 bits (299), Expect = 2.444e-27
Identity = 79/331 (23.87%), Postives = 156/331 (47.13%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E+ Y++++  I    L  L++++++    +++   +F NI E+ + +   W   M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  D      +   IS V++F++++N  ++ ++   +L    S +  +  +E     +   +  +   ++T PM   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK +  R +++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  397 AVWELLHTEVSYIRKLRVITNLFLCCLLNLQESGLLCEVEAERLFSNIPEIAKLHRGLWGSVMVPVLEKARRTRALLQPSDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYVTWAEKHQQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTDDPRTKEAIVTMISSVERFIHHVNTCMRQRQERQRLAGVVSRIDAYEVVEGSNDEVDKLLKEFLHLDLTAPMPGTS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAE--RTKVIRPPLLVDKIVCRE----LRDPGSFLLIYLNEFHSAVGAY 719
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Mouse
Match: Plekhg5 (pleckstrin homology domain containing, family G (with RhoGef domain) member 5 [Source:MGI Symbol;Acc:MGI:2652860])

HSP 1 Score: 119.783 bits (299), Expect = 2.761e-27
Identity = 79/331 (23.87%), Postives = 156/331 (47.13%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E+ Y++++  I    L  L++++++    +++   +F NI E+ + +   W   M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  D      +   IS V++F++++N  ++ ++   +L    S +  +  +E     +   +  +   ++T PM   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK +  R +++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  410 AVWELLHTEVSYIRKLRVITNLFLCCLLNLQESGLLCEVEAERLFSNIPEIAKLHRGLWGSVMVPVLEKARRTRALLQPSDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYVTWAEKHQQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTDDPRTKEAIVTMISSVERFIHHVNTCMRQRQERQRLAGVVSRIDAYEVVEGSNDEVDKLLKEFLHLDLTAPMPGTS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAE--RTKVIRPPLLVDKIVCRE----LRDPGSFLLIYLNEFHSAVGAY 732
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. UniProt/SwissProt
Match: sp|Q8R0J1|PKHG6_MOUSE (Pleckstrin homology domain-containing family G member 6 OS=Mus musculus OX=10090 GN=Plekhg6 PE=2 SV=2)

HSP 1 Score: 133.65 bits (335), Expect = 4.720e-31
Identity = 80/333 (24.02%), Postives = 159/333 (47.75%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGF----PTIEEYIKAIFPIPPYPVFNMTCP-MQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFST 1521
             +WEL+T+E++YL+++  +       L+++++     ++   ++FGN+  + R++  FW E ++ + +  +      D   + +GF  F ++F PY  YC+ +     Y  + +  +  F  F++WC     S R  L   +  P QR+T+Y L L  + K   +      L+  I  V+ F+ +IN  ++  E    L      +  +    P+ EE  K +    P+   ++  P + V  EY    R L+ +  +R+K+     + V + LF+D+L+  KP +K    R +++  P+ L++LV       + +  S  L  + +FQC S+
Sbjct:  165 ALWELLTTELIYLRKLKIMTDLLAAGLLNLQRVGLLTEVSAETLFGNVPNLIRAHRRFWEEVLQPILEDTRTSGQPLDPVSLQNGFLTFGQRFQPYVQYCLRVKQTMAYAREQQDTNPLFHTFVQWCEKHKRSGRQTLGDLLIKPHQRITKYPLLLQAVRKRSPEPRAQEALNAMIEAVESFLRHINGQVRQGEEQESLMAVAQRIGPYEVLEPSSEEVEKNLR---PFSTLDLMTPVLGVAPEY---TRQLLLEGPVRVKEGREGKMDVYLFLFSDVLLVTKPQRKAD--RAKVIRPPLMLEKLVCRP----LRDPNSFLLIHLTEFQCVSS 485
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. UniProt/SwissProt
Match: sp|Q3KR16|PKHG6_HUMAN (Pleckstrin homology domain-containing family G member 6 OS=Homo sapiens OX=9606 GN=PLEKHG6 PE=1 SV=3)

HSP 1 Score: 132.109 bits (331), Expect = 1.674e-30
Identity = 86/359 (23.96%), Postives = 167/359 (46.52%), Query Frame = 1 
Query:  463 EMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGF----PTIEEYIKAIFPIPPYPVFNMTCPM-QVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFST 1521
            EM QE+ H+Q                 +WEL+T+E++Y++++  +       L+++++     ++   ++FGN+  + R++  FW E +    +  +      D   + SGF  F ++F PY  YC+ +     Y  + +  +  F  F++WC     S R  L   +  P QR+T+Y L L  ++K   +      L+  I  V+ F+ +IN  ++  E    L      +  +    P  +E  K +    P+   ++T PM  V SE+    R L+ +  +R+K+     + V + LF+D+L+  KP +K  + +  ++  P+ L++LV       + +  S  L  + +FQC S+
Sbjct:  154 EMSQELCHQQE---------------ALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLR---PFSTLDLTSPMLGVASEH---TRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAK--VIRPPLMLEKLVCQP----LRDPNSFLLIHLTEFQCVSS 485
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. UniProt/SwissProt
Match: sp|Q6RFZ7|PKHG5_RAT (Pleckstrin homology domain-containing family G member 5 OS=Rattus norvegicus OX=10116 GN=Plekhg5 PE=1 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 4.018e-27
Identity = 80/337 (23.74%), Postives = 158/337 (46.88%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIE-------EYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E+ Y++++  I    L  L++++++    +++   +F NI E+ R +   W+  M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  +      +   IS V++F++++N  ++ ++   +L    S +  +  +E       +++K           ++T PM   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK +  R +++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  376 AVWELLHTEVSYIRKLRVITNLFLCCLLNLQESGLLCEVEAERLFSNIPELARLHRGLWSSVMVPVLEKARRTRALLQPSDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRSLLRDNDLFRAYVTWAEKHQQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTDEPRAKEAIITMISSVERFIHHVNTCMRQRQERQRLAGVVSRIDAYEVVEGSNDEVDKFLKEFL------HLDLTAPMPGTS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAE--RTKVIRPPLLVDKIVCRE----LRDPGSFLLIHLNEFHSAVGAY 698
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. UniProt/SwissProt
Match: sp|Q66T02|PKHG5_MOUSE (Pleckstrin homology domain-containing family G member 5 OS=Mus musculus OX=10090 GN=Plekhg5 PE=1 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 2.002e-26
Identity = 79/331 (23.87%), Postives = 156/331 (47.13%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E+ Y++++  I    L  L++++++    +++   +F NI E+ + +   W   M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  D      +   IS V++F++++N  ++ ++   +L    S +  +  +E     +   +  +   ++T PM   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK +  R +++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  410 AVWELLHTEVSYIRKLRVITNLFLCCLLNLQESGLLCEVEAERLFSNIPEIAKLHRGLWGSVMVPVLEKARRTRALLQPSDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYVTWAEKHQQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTDDPRTKEAIVTMISSVERFIHHVNTCMRQRQERQRLAGVVSRIDAYEVVEGSNDEVDKLLKEFLHLDLTAPMPGTS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAE--RTKVIRPPLLVDKIVCRE----LRDPGSFLLIYLNEFHSAVGAY 732
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. UniProt/SwissProt
Match: sp|O94827|PKHG5_HUMAN (Pleckstrin homology domain-containing family G member 5 OS=Homo sapiens OX=9606 GN=PLEKHG5 PE=1 SV=3)

HSP 1 Score: 116.701 bits (291), Expect = 1.880e-25
Identity = 76/331 (22.96%), Postives = 155/331 (46.83%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             +WEL+ +E  Y++++  I+   L  L++++++    +++   +F NI E+ + +   W   M  V +  +    +      + GF  F   F PY  YCM      EY+     ++D FR ++ W        RL L   +  P QRLT+Y L L  ++++  +      +   I  V++F++++N  ++ ++   +L    S +  +  +E     +   +  +   ++T P+   S    E R L+ + +LR+K+     + V   LFTDLL+  K +KK +  R +++  P+ +D++V  +    + +  S  L  +N+F      Y
Sbjct:  396 AVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGAS--PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAE--RTRVIRPPLLVDKIVCRE----LRDPGSFLLIYLNEFHSAVGAY 718
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. TrEMBL
Match: E9I9G0 (Uncharacterized protein (Fragment) OS=Solenopsis invicta OX=13686 GN=SINV_13754 PE=4 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 5.368e-34
Identity = 94/353 (26.63%), Postives = 172/353 (48.73%), Query Frame = 1 
Query:  514 SKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIE-----EYIKAIFPIPPYPVFNMT------CPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLS 1536
            S+ + ++   +WEL  +E+ Y+K +  +    +  L +++ +    ++D   +F NIL+++ +N  FWTEY+  +    ++     D  H++ GF  F + F PY  YC   S   +Y      ++  F  +L WC      NRL L   + MP QRLTRYSL L  I K   ++++  EL   I  VD FV ++N +++  E  ++L +  S L  +  +E     E ++ +  +  Y   ++T      CP       ++ +R L+ +  L+L+      + V VLL TD+L+  KP  K     L+++  P  +D++ I++    ++   S+ L  +N++   S    LS
Sbjct:  112 SEKQTQQQTALWELAETEVAYIKTLKVVTDLFMACLCNLQASNILIEVDRLKLFNNILDIYAANRYFWTEYLLAMVNASRSSGQPLDPGHLLLGFETFEQTFAPYTRYCAEQSKCQQYCKDRLNDNQLFTAYLVWCETQKDCNRLKLMDILVMPMQRLTRYSLLLKAIYKNTENEEQRVELIHMIKSVDGFVVSVNAALRRNEEAAQLEHAASRLECYDVVETKGLDEEVEKLIRL--YSNLDITTAPMPGCP-------KDSLRTLLREGDLKLRDASTSKMEVHVLLLTDMLLICKPSTKKM---LKIIRQPYVVDRIRIHE----VKEPSSLGLVYLNEYGTVSAALILS 448
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. TrEMBL
Match: U4UQ61 (DH domain-containing protein (Fragment) OS=Dendroctonus ponderosae OX=77166 GN=D910_12504 PE=4 SV=1)

HSP 1 Score: 150.599 bits (379), Expect = 6.927e-34
Identity = 91/314 (28.98%), Postives = 157/314 (50.00%), Query Frame = 1 
Query:  523 RNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIK-QTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI----PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYD 1449
            + ++   +WELI +E+ Y+K +  +    L  L D++ +  F ++D   +F NI E+  +NVIFW   +  + + ++       + +M+ GF+  ++ F PY  YC   S  C++  +  LES+ F  +L WC +    NRL L   +  P QRLT+Y L L  I+K   +D E   L   I  VD+FVNN+N S+K ++   +L+   + +  +  +E     I  I      +   ++T PM +    E +   L+  D L+LK      I V   L TD+L+  KP  K     ++++  P  +D+LV+ +
Sbjct:  272 QQQQQTALWELIKTEVAYIKTLKVVTDLFLGCLRDLQSKNLFKEIDTEKLFSNITEILGANVIFWRNTLFPLVRDMRKYKRPSCLENMLEGFSRLAETFTPYYKYCAEQS-RCQHYCRENLESEVFTAYLTWCESQKDCNRLRLMDILVQPMQRLTKYGLLLKAILKNTDEDVERESLQSMIRMVDEFVNNVNSSLKRRQDKERLKGIIARIESYDIVESKDDDIERILKREKSFTQLDLTRPM-LGCPPERKRHLLLEGD-LKLKDSGASKIEVHCFLLTDMLLICKPSTKKGVATMRVIRQPYLVDRLVVQE 582
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. TrEMBL
Match: F4WJV8 (Pleckstrin-like proteiny domain-containing family G member 5 (Fragment) OS=Acromyrmex echinatior OX=103372 GN=G5I_05992 PE=4 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 4.058e-33
Identity = 93/353 (26.35%), Postives = 169/353 (47.88%), Query Frame = 1 
Query:  514 SKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIE-----EYIKAIFPIPPYPVFNMT------CPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLS 1536
            S+   ++   +WEL  +E+ Y+K +  +    +  L  ++ +    ++D   +F NI +++ +N  FWTEY+  +    ++     D  H++ GF  F + F PY  YC   S   +Y      ++  F  +L WC      NRL L   + MP QRLTRYSL L  + K   ++D+  EL   I  VD FV ++N +++  E  ++L +  S L  +  +E     E ++ +  +  Y   ++T      CP       ++ +R L+ +  L+L+      + V VLL TD+L+  KP  K     L+++  P  +D++ I++    ++   S+ L  +N++   S    LS
Sbjct:  275 SEKHTQQQTALWELAETEVAYIKTLKVVTNLFMACLCSLQASNILIEVDRLKLFSNIPDIYAANRYFWTEYLLAMVNASRSSGQPLDPGHLLLGFETFEQTFAPYTRYCTEQSKCQQYCKDRLNDNQLFTAYLVWCETQKDCNRLKLMDILVMPMQRLTRYSLLLKAVYKNTENEDQRTELIHMIKSVDDFVVSVNAALRRNEEAAQLDHAASRLECYDVVESKGLDEEVEKLIKL--YSNLDITTAPMPGCP-------KDSLRTLLREGDLKLRDAATSKMEVHVLLLTDMLLICKPSTKKM---LKIIRQPYVVDRIRIHE----VKEPSSLGLVYLNEYGTVSAALILS 611
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. TrEMBL
Match: A0A1B6F2M6 (DH domain-containing protein (Fragment) OS=Cuerna arida OX=1464854 GN=g.12192 PE=4 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 5.062e-33
Identity = 91/347 (26.22%), Postives = 170/347 (48.99%), Query Frame = 1 
Query:  529 EKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKN 1563
            ++   +WELI +E+ Y+  +  +    L  L +++       +D   +F NI E++ SN +FW+ Y+  +    +    V + + ++ GF  F + F PY  YC   S   +Y  +   ES+ F  +L WC      NRL L   +  P QR+T+YSL L  I K    DD    L Q IS VD FVN++N +++ K+   KLR   S +  +  +E   + +   +  Y   ++TCPM       ++ R L+ +  L++K      + V   LFTD+L+  K   +  + R ++L  P  +++L++ +   +  +  ++ +  +++++     + LS+  + + KN
Sbjct:  242 QQQTAVWELIHTEVAYIHTLKVVTDLFLSCLTNLQAANILCDVDKTRLFSNITEIYSSNKLFWSTYVLPMLNASRESRGVLNPQLLLDGFIRFEEIFRPYTKYCAEQSQCQQYCRERHGESELFTAYLVWCETQKDCNRLRLMDILVKPMQRITKYSLLLKAIQKHTEADDLRLSLDQMISRVDIFVNSVNTTLRQKQDLEKLRAVISRIEAYDVVESKDEDLERLVKSYNDLDLTCPM--PGCCNSQRRHLLLEGDLKIKDNVTSKMDVHCFLFTDMLLVCKATNRRSEGRFKVLRQPYLVERLIVQE---LNRDPATLAVVYLSEYRVPCGAFLLSSPDTKALKN 583
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. TrEMBL
Match: A0A158NEM6 (Uncharacterized protein OS=Atta cephalotes OX=12957 GN=105619062 PE=4 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 6.397e-33
Identity = 93/353 (26.35%), Postives = 169/353 (47.88%), Query Frame = 1 
Query:  514 SKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIE-----EYIKAIFPIPPYPVFNMT------CPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLS 1536
            S+   ++   +WEL  +E+ Y+K +  +    +  L  ++ +    ++D   +F NI +++ +N  FWTEY+  +    ++     D  H++ GF  F + F PY  YC   S   +Y      ++  F  +L WC      NRL L   + MP QRLTRYSL L  + K   ++D+  EL   I  VD FV ++N +++  E  ++L +  S L  +  +E     E ++ +  +  Y   ++T      CP       ++ +R L+ +  L+L+      + V VLL TD+L+  KP  K     L+++  P  +D++ I++    ++   S+ L  +N++   S    LS
Sbjct:  565 SEKHTQQQTALWELAETEVAYIKTLKVVTNLFMACLCSLQASNILIEVDRLKLFSNIPDIYAANRYFWTEYLLAMVNASRSSGQPLDPGHLLLGFETFEQTFAPYTRYCTEQSKCQQYCKDRLNDNQLFTAYLVWCETQKDCNRLKLMDILVMPMQRLTRYSLLLKAVYKNTENEDQRTELIHMIKSVDDFVVSVNAALRRNEEAAQLDHAASRLECYDVVETKGLDEEVEKLIKL--YSNLDITTAPMPGCP-------KDSLRTLLREGDLKLRDAATSKMEVHVLLLTDMLLICKPSTKKM---LKIIRQPYVVDRIRIHE----VKEPSSLGLVYLNEYGTVSAALILS 901
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Cavefish
Match: plekhg6 (pleckstrin homology domain containing, family G (with RhoGef domain) member 6 [Source:ZFIN;Acc:ZDB-GENE-030131-2517])

HSP 1 Score: 102.834 bits (255), Expect = 3.941e-22
Identity = 93/385 (24.16%), Postives = 181/385 (47.01%), Query Frame = 1 
Query:  514 SKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFS--IFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDC-FRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPT------IEEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSH-AMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYFLKKLSFAKMHYETIMLQTNQ 1638
            SK +  +   +WEL+ +E+VY+ ++  I +  L  L  + Q  F  L+V S  +F N+  +  ++ +FW + M  +   ++      D   +  G   F+++F  Y  YC       E+ T+ +LES+  F+ +L W        R+ L      P QR+T+Y L L  I+K   D      L + ++ V +F+++IN  ++ K+    L      + G+ T      I+++I+          F++T P+Q        +R L+ ++TL+++      + V  LLFTD+L+  K  KK+++ +  ++  P++L++     +H A +++  S  L E +   C   +Y +S     S       ++  ++ AK   +T+    NQ
Sbjct:  148 SKTQRHQQEALWELLQTELVYINKLTIITELVLSALEYVHQRGF-LLEVTSAQLFSNLPSILEAHKLFWRDVMYPMLINVRQTGQPFDPLKLEPGCLQFAERFSAYLDYCWEEERNVEF-TRRQLESNPQFQAYLLWVETHPQCVRMRLGDMQAKPHQRITKYPLLLKAILKTTEDTHTQGTLHRMLNSVGQFLDSINDYLQFKDDELALFDLSQRIEGYETQGMNEEIDKFIQEAC------RFDLTSPVQGMG--PTVIRKLLMEETLKVRGRKDSKLEVVALLFTDVLLLTKSQKKSEKHK--VVRPPVSLER-----THCAELKDGYSFVLVEASDLGCAVNVYSVSAPSPES----CTAWVSAINQAKEALDTLRRNQNQ 511
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Cavefish
Match: plekhg5a (pleckstrin homology domain containing, family G (with RhoGef domain) member 5a [Source:ZFIN;Acc:ZDB-GENE-060503-766])

HSP 1 Score: 86.6557 bits (213), Expect = 3.077e-17
Identity = 53/224 (23.66%), Postives = 114/224 (50.89%), Query Frame = 1 
Query:  859 EYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
            EY+     +++ FR+++ W       +RL L   +  P QRLT+Y L L  ++K+  D      +++ I+ V+ F+N+++  ++ +E   KL    S +  +  +E   + +  I   Y  F++T P+   S   +E+R L  +  L++K+     + V   LFTD+L+  KP+K+ +  +++++  P+ +  +V  +    +++  +  L  +N+F+     Y
Sbjct:    8 EYMRTLLKDNELFRIYVTWAETHKQCSRLKLTDMLVKPHQRLTKYPLLLKSVLKKTDDPAAREAVTRMIAVVEGFINSVDSQMRQREEKQKLTAIASRIEAYEAVEGASEEVEKILREYNQFDLTAPVMGAS--PDEIRQLHLEGALKMKEGKESRMDVYCFLFTDVLLITKPVKRVE--KVKVIRQPLVIQNVVCRE----LKDPGAFLLIYLNEFRTAVASY 223
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Cavefish
Match: plekhg7 (pleckstrin homology domain containing, family G (with RhoGef domain) member 7 [Source:ZFIN;Acc:ZDB-GENE-070410-15])

HSP 1 Score: 69.3218 bits (168), Expect = 5.475e-12
Identity = 80/333 (24.02%), Postives = 137/333 (41.14%), Query Frame = 1 
Query:  541 VIWELITSEIVY-LKQIHFIVKTPLPILIDIK-QTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVP-----YKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPPYPVFNMTCPMQVKSEYENEV--RCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQ-------------------------CRLQLLDHPIALDQL 1437
             IWEL TSE VY L Q+  + +  L  L D++ +     +D + +F N+ E+   +  F T     + +++K     P+     +      K F        + YC+N +    Y+   +   D F  +++WC   +   RL L   +  P QR TRY L L  I +  S ++E   L   +  VD+ + ++   +K  +   K++  +  L   P  E   KA  P     +             EN V  R L+++  L L + + K   V + LF + L+  K IK++++                         C   +LD PI+LD+L
Sbjct:   27 AIWELFTSECVYFLDQLMVLKEVFLTTLSDLQMRDCLQDIDSWGLFANLNELCLVSFGFLT----SLLRVIKELWATPETDVTQTLLAVMKKAFGESICHCLQKYCLNYTTAILYLDSLKTRED-FGSYVKWCERKEQCRRLQLKDLLVAPLQRFTRYPLLLKNIERRSSGEEEEGGLQSVVELVDRAICDLEGKVKWLDNYQKVKQLKEALVWLPVWEIDKKAHVPESLKHLLKAVT-------LENLVSNRVLLYEGKLILTE-NAKLHEVYLFLFDEFLLITK-IKRSKKKSGGVEAHLLRPAVGQELETLLQEGCSFTVLDQPISLDRL 345
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Cavefish
Match: PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1 [Source:HGNC Symbol;Acc:HGNC:20884])

HSP 1 Score: 61.2326 bits (147), Expect = 3.184e-9
Identity = 55/213 (25.82%), Postives = 96/213 (45.07%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFR--LFLEWCRNSDSS--NRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQ-AISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGF 1164
            V+ E++ +E  Y++ +  IV+  L  + +  +      D  S+FGNI E++  N         D+   L+ C+  P    +   F   S++F  Y  YC N      Y     + S+C R     ++ R    S  + L L +++  P QR+ +Y L L  I      D E++E+ Q AI  + +   +IN   +  E T +L+  QS+L  +
Sbjct:   88 VVQEILETERTYVQDLRSIVQDYLECISNQARPLLGVEDRNSLFGNIREIYGFN--------RDLLHDLEKCNANPVA--IAECFVAKSEEFHIYTQYCTN------YPRSVAVLSECMRNKAVAKFLRERQESLKHSLPLGSYLLKPVQRILKYHLLLHEIATHLEKDSEMHEVVQEAIDTMQRVAWHINDMKRKHENTIRLQEIQSLLTNW 284
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Cavefish
Match: tiam1b (TIAM Rac1 associated GEF 1b [Source:ZFIN;Acc:ZDB-GENE-120221-1])

HSP 1 Score: 58.9214 bits (141), Expect = 1.478e-8
Identity = 48/204 (23.53%), Postives = 101/204 (49.51%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVK---TPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRH-------MISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECS-DDDEIYELSQAISEVDKFVNNINKSIKVKE 1119
            VIWEL+ +E  Y+K ++ ++    TPL      K++F  + ++  +FGN+ E+    V F    +ED  +++ + + +  +         +   F  ++ +F  Y ++C + +   + + K + +   F+ FL+  RN    +   L++++  P QR+ +Y L L  +      D +E Y L  A+  ++K  ++IN+  K+ E
Sbjct:   74 VIWELVETERTYVKDLNCLIGRYLTPLQ-----KESFLTQDELDVLFGNLPEMVEFQVEFL-RTLEDGARLVPDLEKLERVEQFKKILFSLGGSFLYYADRFKIYSAFCASHTKVPKVLVKAKTDP-AFKAFLDE-RNPKQQHSSTLESYLIKPIQRVLKYPLLLRELYTLTDPDSEEHYHLDVAMKAMNKVASHINEMQKLHE 269
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008020.1 (pep scaffold:Pmarinus_7.0:GL476484:132482:154779:-1 gene:ENSPMAG00000007248.1 transcript:ENSPMAT00000008020.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.6178 bits (148), Expect = 1.836e-10
Identity = 53/206 (25.73%), Postives = 96/206 (46.60%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQ-AISEVDKFVNNINKSIKVKEMTSKLRYFQSIL 1155
            V+ E++ +E +Y++ +  IV+  L  +        P  DV ++FGNI E+++ N    +E +E+    L++C N P    +   F   S  F  Y  YC N  +  E +TK        + F +    +   + L L +F+  P QR+ +Y L L  I K      + YE+ Q A+S +     +IN+  +  E   +++  + +L
Sbjct:   13 VVLEILDTERMYVRHLKSIVEDYLRAI----SQRLPNDDVNTLFGNIKEIYKFN----SELLEE----LEDCSNDPVA--IAECFVEKSGGFEIYTQYCTNFPSSMELLTKCMRTKSTAKFFRD--HQAALKHNLPLGSFLLKPVQRILKYHLLLQEIEKRLDKSTDGYEVVQDALSAMHGVAWHINEMKRKHEHAIRIQELRGLL 202
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008024.1 (pep scaffold:Pmarinus_7.0:GL476484:132482:154761:-1 gene:ENSPMAG00000007248.1 transcript:ENSPMAT00000008024.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 2.971e-10
Identity = 54/213 (25.35%), Postives = 101/213 (47.42%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFF-------PKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQ-AISEVDKFVNNINKSIKVKEMTSKLRYFQSIL 1155
            V+ E++ +E +Y++ +  IV++ + +   I+Q +        P  DV ++FGNI E+++ N    +E +E+    L++C N P    +   F   S  F  Y  YC N  +  E +TK        + F +    +   + L L +F+  P QR+ +Y L L  I K      + YE+ Q A+S +     +IN+  +  E   +++  + +L
Sbjct:    7 VVLEILDTERMYVRHLKSIVESYVNL---IEQDYLRAISQRLPNDDVNTLFGNIKEIYKFN----SELLEE----LEDCSNDPVA--IAECFVEKSGGFEIYTQYCTNFPSSMELLTKCMRTKSTAKFFRD--HQAALKHNLPLGSFLLKPVQRILKYHLLLQEIEKRLDKSTDGYEVVQDALSAMHGVAWHINEMKRKHEHAIRIQELRGLL 204
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003234.1 (pep scaffold:Pmarinus_7.0:GL476714:93500:128189:1 gene:ENSPMAG00000002944.1 transcript:ENSPMAT00000003234.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.9062 bits (115), Expect = 3.370e-6
Identity = 48/211 (22.75%), Postives = 92/211 (43.60%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDE----IYELSQAISEVDKFVNNINK----SIKVKEMTSKLRYFQS 1149
            V+ E++ +E +Y+K +  IV+  L  +ID         +V ++FGNI +++  N         ++   L++C   P    +   F   ++ F  Y  YCMN     + + +        R F E    +   + L L  ++  P QR+ +Y L L  I        E    I E +  ++ V   +N+I +    + +V+E+ ++L  +Q 
Sbjct:  119 VVLEVLQTEQMYVKDLRSIVENYLGCIIDTPDLPLSPEEVCTLFGNIEDIYALN-------FSELLHELESCAFDPVA--IADCFVAKNEAFHIYTQYCMNYPNAIDVLNECARSVAMTRFFGEV--QASLKHSLPLGCYLLKPVQRILKYHLLLREIANHYEGLAEGMEVIEEATATMTSVAWHINDIKRKHEHAARVQEIQAQLVQWQG 318
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Sea Lamprey
Match: dnmbp (dynamin binding protein [Source:NCBI gene;Acc:100005174])

HSP 1 Score: 48.9062 bits (115), Expect = 4.329e-6
Identity = 59/253 (23.32%), Postives = 97/253 (38.34%), Query Frame = 1 
Query:  400 SAERVSNPIDSAYSFIDELTTEMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNF----SKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRN-SDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKEC--SDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLR 1137
             A  V  P + A      L    P     +              +  V+ EL+ +E  YL  + F  +    I I +++T    LDV  +FGN+  V   N  F+          +   D+V     ++S    F    S+    YK YC N       +   E + D         +N  + SN + L   +  P QR+ RY L L  ++     S  D+   LS+A+  + +  +NIN+  + K++  K R
Sbjct:  712 GAAHVGGPPNGAAPEARALQGPQPGRALEK--------------RKMVLEELLRTERDYLADLQFCREE---IYIPLRKTQVANLDVEGLFGNLEAVLEVNARFYESLQLSADGRVSYGDDV-----LLSPGEIFLAFKSELEEVYKVYCRNHDDAISLLEASEKDEDIKAQMAVCLKNMRERSNYINLGALLIKPVQRVMRYPLLLTELLGATPPSHPDQP-SLSKALVALRQLNHNINEFKRRKDLVVKYR 941
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Nematostella
Match: EDO39608 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9N2])

HSP 1 Score: 117.472 bits (293), Expect = 4.879e-27
Identity = 93/382 (24.35%), Postives = 184/382 (48.17%), Query Frame = 1 
Query:  514 SKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIK-QTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSD-SSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTI-----EEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKL--SNDKSSSFKNPVKYFLKKLSFAKMHYETIMLQT 1632
            +K + ++   IWEL+ +E+ Y+ ++  + K  +  L +++ + F   +++  +F NI +++  N  FW + + +V +  +      +   M   F  F K+F PY +YCM  S   +Y  +  +E++ FR ++ WC      +NRL L  ++  P QRLT+Y L L  I K+  D++    + + I  V+  ++ +N +++     +KLR   + +    T+     EE  K +       +      M +        RC+IH+  LRL +   K + V V LFTDLL+  KP K +   + +++  P+ +D+L ++ S    ++  +  L  +N++      + L  SN   + + + ++   K L  AK+   T  + +
Sbjct:  411 TKKQKDQQEAIWELLFTEVTYIHKLSIVKKLFILCLRNVQSEGFLLDVEIEKLFSNIEDIYELNYSFWVDCLCEVAEKSRKTGKPLNPMDMNEAFPMFDKRFEPYITYCMEESRCLKYFKEKIIENEDFRTYITWCEEHRLCTNRLKLTDYLVKPMQRLTKYPLLLKAIHKKTQDEEMKEGIWKMILTVESLLSKVNGAMREMYERNKLRSVANRIQDNYTVIEAVNEEMEKILVNYNSLDLMEHIPGMDIP-------RCVIHEGPLRLVEKQGK-MDVHVFLFTDLLLITKPKKAD---KYRVIKPPMMVDKLYVHAS----KDPGTFLLVYVNEYNTVVHAFALQGSNADQTQWMDAIRKAQKLLLVAKLGQGTATMGS 777
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Nematostella
Match: EDO49694 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG07])

HSP 1 Score: 79.337 bits (194), Expect = 3.519e-15
Identity = 71/288 (24.65%), Postives = 133/288 (46.18%), Query Frame = 1 
Query:  526 NEKSFVIWELITSEIVYLKQIHFIVKT----PLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVP-YKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSD-DDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAK 1371
            N++   +WEL  SE+VYL     +++     PL I+  +++ +   +D   IF N+ E+   +  F  + +  VF+  ++         +++ F  F  +  P Y+ YC+N S    Y+ + + +S+ F+ F++WC       RL L   +  P Q LT+Y L L  I K  S+ DD+   LS  I  V+  +  +   +K      +L+  Q  L  +P+I E     + +P + +  +      +    +  R L+H+  L L +  ++   V   LF D+L+  +
Sbjct:  674 NKRREALWELFHSEVVYLMDHVLVLREVFLEPLRIVQQMEE-YLQNVDPNMIFCNVEELCEVSAKFAKDLLL-VFKGDQSNSQFGSTAAVVNAFTEFGWRVHPQYQEYCLNYSKVLGYLDQCK-KSEDFQEFVKWCEADPRCKRLQLTDLLVAPLQHLTKYPLLLKNIRKRTSEGDDQHSSLSSVIKSVELSIKELEGKVKSLANLERLQELQKCLV-WPSIVELDPKTY-VPEF-LRGILAKQPCEGLLTSANRQLLHEGHLVLHESTKQ--DVYAFLFDDMLLLTR 953
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Nematostella
Match: EDO32328 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVF8])

HSP 1 Score: 53.5286 bits (127), Expect = 2.356e-7
Identity = 60/254 (23.62%), Postives = 106/254 (41.73%), Query Frame = 1 
Query:  496 TESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPL----------PI-LIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRL-FLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIY----ELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPP 1209
            T+  +  ++  ++S ++ EL+T+E  Y++ +  IV+  L          PI L D ++T         IFGNI E+   +         D  + L  C   P  + +   F     +F  Y  YC N  A         L+     + ++  C+ ++  ++L L  ++  P QR+T+Y L L  +MK   +D   Y    E   A+  V + +N++  S  +K     L     +L   P +  Y  A   +PP
Sbjct:  473 TDGVDTPEVIKKRSQIMAELVTTEKDYVRDLDHIVRGYLHEFERAAGKIPIELFDQRET---------IFGNIEEILEFHRC-------DFLEELNKCSETP--KSVGKVFTERRGEFEKYALYCKNKPA------SEALQQQLINVPYIRECQ-ANLGHKLPLTAYLLKPVQRITKYQLLLREMMKNTKNDRIAYMNLMEAFHAMQNVLRHLNDVMHSSGLKGYHGNLGDLGKLLLQDPFLVWYTGARRKLPP 701
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Nematostella
Match: EDO39595 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9L2])

HSP 1 Score: 51.2174 bits (121), Expect = 1.181e-6
Identity = 72/299 (24.08%), Postives = 127/299 (42.47%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQI-----HFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDD-DEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPP-YPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDH 1416
             ++E+ITSE  YLK +     HF+    L    D  Q+   K     +FGN+  V  ++  F T     + Q  +    +  I  +I    + ++ F  Y  YC +   Y + I K   ++  F   +       ++  L   +F+ +P QR+TR  L +D I   C +  DE     +A+  ++K V++ N+  +  E   +L   Q      P IE  +K +  +     +      + V  E+++ +R          K+I  KT  V + LF DLL+     KK    + ++LD+
Sbjct:   28 AMFEVITSEASYLKSLNILGSHFMDSPELQA--DTAQSVVEKSQQRVLFGNVKGVLEASEKFLTA----LRQRQRKSYVISTISDIIE--EHATQYFDIYIKYCSH-QVYQDRILKELGKNPRFVEAVRRLEQCSTAQCLSFQSFLVLPMQRITRLPLLVDAICHRCEEGSDEFVRTDKALKSINKVVHDCNEGARKMERMEELIALQ------PLIEFAVKPVALVSSNRWLLRRGEVLLVTEEFKSPLR----------KKI--KTKPVYMFLFNDLLLMC---KKKSDIKYRVLDY 296
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Medaka
Match: plekhg5b (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:101161470])

HSP 1 Score: 130.183 bits (326), Expect = 1.067e-30
Identity = 82/331 (24.77%), Postives = 159/331 (48.04%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ R +   W + M  V    +    + D   +  GF  F  +F PY  YCM   +  EY+     +++ FR ++ W       NRL L   +  P QRLT+Y L L  ++K+  +      +S  +  V+ F+N+++  ++ ++   KL    + +  +  +E   + +  I   Y  F++  PM+  S    E R L  +  LR+K+     + V   LFTDLL+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F      Y
Sbjct:  404 AIWELLNTEAAYIKKLRVITDLFLSGLLNLQESGLLSEVEPTRLFSNIQEIVRLHTSLWNQVMLPVLHRAREARALLDPTLLYDGFRTFDTRFQPYIRYCMEEESCMEYMRTLLRDNELFRKYITWAETKKQCNRLKLADMLAKPHQRLTKYPLLLKSVLKKTDELSARDIVSSMVVMVESFINSVDSQMRQRQERQKLATISARIDCYEAVEGSSEEVEKILKEYNRFDLMAPMRGTS--PEETRQLQLEGALRMKEGKDSRMDVYCFLFTDLLLITKPVKRLE--KVKVIRQPLLIHNIVCKE----LKDPGSFILIYLNEFNSAVAAY 726
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Medaka
Match: plekhg5b (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:101161470])

HSP 1 Score: 130.183 bits (326), Expect = 1.261e-30
Identity = 82/331 (24.77%), Postives = 159/331 (48.04%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ R +   W + M  V    +    + D   +  GF  F  +F PY  YCM   +  EY+     +++ FR ++ W       NRL L   +  P QRLT+Y L L  ++K+  +      +S  +  V+ F+N+++  ++ ++   KL    + +  +  +E   + +  I   Y  F++  PM+  S    E R L  +  LR+K+     + V   LFTDLL+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F      Y
Sbjct:  360 AIWELLNTEAAYIKKLRVITDLFLSGLLNLQESGLLSEVEPTRLFSNIQEIVRLHTSLWNQVMLPVLHRAREARALLDPTLLYDGFRTFDTRFQPYIRYCMEEESCMEYMRTLLRDNELFRKYITWAETKKQCNRLKLADMLAKPHQRLTKYPLLLKSVLKKTDELSARDIVSSMVVMVESFINSVDSQMRQRQERQKLATISARIDCYEAVEGSSEEVEKILKEYNRFDLMAPMRGTS--PEETRQLQLEGALRMKEGKDSRMDVYCFLFTDLLLITKPVKRLE--KVKVIRQPLLIHNIVCKE----LKDPGSFILIYLNEFNSAVAAY 682
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Medaka
Match: plekhg5b (pleckstrin homology and RhoGEF domain containing G5 [Source:NCBI gene;Acc:101161470])

HSP 1 Score: 129.798 bits (325), Expect = 1.500e-30
Identity = 82/331 (24.77%), Postives = 159/331 (48.04%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQT-FFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPI-PPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIY 1527
             IWEL+ +E  Y+K++  I    L  L++++++    +++   +F NI E+ R +   W + M  V    +    + D   +  GF  F  +F PY  YCM   +  EY+     +++ FR ++ W       NRL L   +  P QRLT+Y L L  ++K+  +      +S  +  V+ F+N+++  ++ ++   KL    + +  +  +E   + +  I   Y  F++  PM+  S    E R L  +  LR+K+     + V   LFTDLL+  KP+K+ +  +++++  P+ +  +V  +    +++  S  L  +N+F      Y
Sbjct:  426 AIWELLNTEAAYIKKLRVITDLFLSGLLNLQESGLLSEVEPTRLFSNIQEIVRLHTSLWNQVMLPVLHRAREARALLDPTLLYDGFRTFDTRFQPYIRYCMEEESCMEYMRTLLRDNELFRKYITWAETKKQCNRLKLADMLAKPHQRLTKYPLLLKSVLKKTDELSARDIVSSMVVMVESFINSVDSQMRQRQERQKLATISARIDCYEAVEGSSEEVEKILKEYNRFDLMAPMRGTS--PEETRQLQLEGALRMKEGKDSRMDVYCFLFTDLLLITKPVKRLE--KVKVIRQPLLIHNIVCKE----LKDPGSFILIYLNEFNSAVAAY 748
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Medaka
Match: plekhg6 (pleckstrin homology and RhoGEF domain containing G6 [Source:NCBI gene;Acc:101169881])

HSP 1 Score: 105.916 bits (263), Expect = 4.391e-23
Identity = 88/374 (23.53%), Postives = 178/374 (47.59%), Query Frame = 1 
Query:  514 SKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQ-TFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDC-FRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPT------IEEYIKAIFPIPPYPVFNMTCPMQ-VKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQC------FSTIYKLSNDKSSSFKNPVKYFLKKL 1590
            +K++  +   +WELI++E++Y+ ++  I    +  L+++ Q  F  ++    +F N+  + +++ +FW E +  + Q ++      D   +  G   F  +F+ Y+ YC       ++ T+ ++ES+  F+ F++W  +     R+ L      P QR+T+Y L L  ++K   +      L   +S V+ F+ +IN  ++ K+    L      + G+        I++Y++ I        FN+ CP++ V  E    VR L+ ++ L+++    + + V  LLF+D+++  K  K+ +   L+++  P+ALD++        +++  S  L E+ + Q       F     LS  K  S  N  K  LK L
Sbjct:  163 TKMQRHQQEALWELISTELIYINKLKIIKDLVIAALLNLHQRGFLQEVSPDQLFYNLPSILQAHQLFWQEVVYPMVQEVRQTGKPFDPMGLEEGCLQFHNRFLVYREYCWEEENSLDF-TRKQMESNPHFQTFIQWVESHPQGERMRLGDMQAKPHQRITKYPLLLKAVLKHTVEPPVQLALIGMLSSVNIFLESINDYMQKKDDEQALYISARRVEGYEVEGITEEIDKYVQEIC------KFNLECPIRGVNPEV---VRKLLLEENLKVRVRKDQKLEVVALLFSDVILLTKIQKRGEG--LKVVRPPLALDRIECI----ALKDGSSFLLVEVGELQSVMNVLIFVAGTSLSCSKWVSTINQAKEMLKNL 520
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Medaka
Match: plekhg7 (pleckstrin homology and RhoGEF domain containing G7 [Source:NCBI gene;Acc:101166867])

HSP 1 Score: 92.4337 bits (228), Expect = 5.343e-19
Identity = 88/350 (25.14%), Postives = 156/350 (44.57%), Query Frame = 1 
Query:  490 QNTESTNESKIRNEKSFVIWELITSEIVY-LKQIHFIVKTPLPILIDIK-QTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNC-----DNVPDIRHMISGFNNFSKQFV-PYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKN--------------QQCRLQL------------LDHPIALDQL 1437
            Q+++ + +S +R  +   IWEL TSE VY L Q+  + +  L  L +++ +     ++V+S+F N+ E+     +  + ++ ++  ++K+         P +  ++S    F +      + YC+N S+   Y+   +L  D F  +L+WC   +   RL L   +  P QRLTRYSL L  + K C +++E   +     +VD  + ++   +K      K++  +  L   P  E   +A  P     +        + S      R L+H+  L L + + K I   + LF + L+  K IKKN              QQ  L+L            LD PI+LD+L
Sbjct:  319 QSSQMSPDSHVRKRQE-AIWELFTSECVYFLDQLMVLNEVFLVTLSNLQLRNCLTDVNVWSLFANVNEL----CLVSSSFLRNLLNVIKDTLEITESGGPTLLELLS--KAFKESICNSLQKYCLNYSSALLYLDSLKLRED-FGSYLKWCERKEQCRRLQLRDLLVAPLQRLTRYSLLLRNVAKRCQEEEERRGMQVIAEQVDTSICDLEGKVKWLHNFQKVKLLRDALVWTPVWERDKRAFIPETLKHLLKTVTADNLISH-----RSLLHEGKLVLTE-NTKLIDAYLFLFDEFLLITK-IKKNKKRSLTSDQNPLRVQQQNLELDQLLKEGSTFTVLDQPISLDRL 653
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Planmine SMEST
Match: SMESG000049531.1 (SMESG000049531.1)

HSP 1 Score: 1202.19 bits (3109), Expect = 0.000e+0
Identity = 655/655 (100.00%), Postives = 655/655 (100.00%), Query Frame = 1 
Query:  124 MLEYFPERRKSSTDLLPLPKTAXXXXXXXXXXXXXXDLLNPFQKRSNDDSLFFIEKQEPFPKRPAKLLQSTKSKTSMTRNNCESITEILQSYSAERVSNPIDSAYSFIDELTTEMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYFLKKLSFAKMHYETIMLQTNQTNVHINVVNSDRNSLNKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLNSCIISDPFINCFDYFDNTDGGSHRNTYRYLLQNCTDKFGKRKHDSIQSFGGESTSTKNDLAMNMFRTSSLGNKHVIQCSTENE 2088
            MLEYFPERRKSSTDLLPLPKTAFFRRSPSPSKRSFSDLLNPFQKRSNDDSLFFIEKQEPFPKRPAKLLQSTKSKTSMTRNNCESITEILQSYSAERVSNPIDSAYSFIDELTTEMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYFLKKLSFAKMHYETIMLQTNQTNVHINVVNSDRNSLNKEEENCTNESSTSHQSGSSSVSDNESENEYLELSNKSLSSSSWIDLENNLNSCIISDPFINCFDYFDNTDGGSHRNTYRYLLQNCTDKFGKRKHDSIQSFGGESTSTKNDLAMNMFRTSSLGNKHVIQCSTENE
Sbjct:    1 MLEYFPERRKSSTDLLPLPKTAFFRRSPSPSKRSFSDLLNPFQKRSNDDSLFFIEKQEPFPKRPAKLLQSTKSKTSMTRNNCESITEILQSYSAERVSNPIDSAYSFIDELTTEMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYFLKKLSFAKMHYETIMLQTNQTNVHINVVNSDRNSLNKEEENCTNESSTSHQSGSSSVSDNESENEYLELSNKSLSSSSWIDLENNLNSCIISDPFINCFDYFDNTDGGSHRNTYRYLLQNCTDKFGKRKHDSIQSFGGESTSTKNDLAMNMFRTSSLGNKHVIQCSTENE 655
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Planmine SMEST
Match: SMESG000023540.1 (SMESG000023540.1)

HSP 1 Score: 145.206 bits (365), Expect = 7.119e-37
Identity = 134/471 (28.45%), Postives = 219/471 (46.50%), Query Frame = 1 
Query:  145 RRKSSTDLLPLPKTAXXXXXXX-XXXXXXXDLLNPFQKRSNDDSLFFIEKQEPFPKRPAKLLQSTKSKTSMTRNNCESITEILQSYSAERVSNPIDSAYSFIDELTTEMPQEMFHRQNTESTNESKIRNEKSF----VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSN 1539
            RRKSSTDLL +PK    RRS S       ++L     K   D +   IE      +  +    S    +S+ RNN  S  E+++     ++ +   SA   +   +  M +  F     E+  +    N++ +     IWEL+ +E  +LKQIHFIV+  +     ++  +FPK+    IF N+ +V   +  FW   +  V +  +    +   R +  GF    +   PY  YC  IS     I+  E  ++ F  +++W  N + SNR  L   +  PF RLT+Y + L  I K  S  DE  E+ + I  VD FV+ +N+ I+   +  KL+   S +  +  IE     + P I  Y   ++T P+Q     E  +R ++ Q +++L++   KT+ VK+ L TD+L+  K  KK    + +++  PI LD + I+ S     N  S     +N F C + +Y  SN
Sbjct:    5 RRKSSTDLLTMPKIMLSRRSQSPSKMLHITELWTSLSKSELDYT--SIEDDNEVDQTDS----SVYHVSSVARNNLSSTNELIRDMCL-KLKDFTKSALPNLS--SNNMSENAFPPSLPENNLQQVYGNKEIYQQQSAIWELMVTEQNFLKQIHFIVQIYVVGFEILRPKYFPKVMSEEIFSNLKDVKTVSFEFWKYCIRPVIENYETTRQMFKPRLLKDGFIKIGEILEPYILYCTEISKCRSSISSLEKSNELFAEYIKWAMNFEESNREPLTDHLAKPFLRLTKYKILLQAIQK-YSGIDEKKEIQEMIDAVDTFVSQVNEKIEETNLMKKLQNLNSFIDTYDVIEPLGDDLIPIINQYSKLDLTAPIQYGR--EKVIREILLQGSVKLREGTSKTVDVKLFLLTDILLITK-FKKKHIGKYKVIKPPIFLDSIKIHKS-----NTNSFICVCLNDFNCITGLYHFSN 457
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Planmine SMEST
Match: SMESG000023540.1 (SMESG000023540.1)

HSP 1 Score: 143.665 bits (361), Expect = 1.049e-36
Identity = 101/334 (30.24%), Postives = 164/334 (49.10%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSN 1539
             IWEL+ +E  +LKQIHFIV+  +     ++  +FPK+    IF N+ +V   +  FW   +  V +  +    +   R +  GF    +   PY  YC  IS     I+  E  ++ F  +++W  N + SNR  L   +  PF RLT+Y + L  I K  S  DE  E+ + I  VD FV+ +N+ I+   +  KL+   S +  +  IE     + P I  Y   ++T P+Q     E  +R ++ Q +++L++   KT+ VK+ L TD+L+  K  KK    + +++  PI LD + I+ S     N  S     +N F C + +Y  SN
Sbjct:   85 AIWELMVTEQNFLKQIHFIVQIYVVGFEILRPKYFPKVMSEEIFSNLKDVKTVSFEFWKYCIRPVIENYETTRQMFKPRLLKDGFIKIGEILEPYILYCTEISKCRSSISSLEKSNELFAEYIKWAMNFEESNREPLTDHLAKPFLRLTKYKILLQAIQK-YSGIDEKKEIQEMIDAVDTFVSQVNEKIEETNLMKKLQNLNSFIDTYDVIEPLGDDLIPIINQYSKLDLTAPIQYGR--EKVIREILLQGSVKLREGTSKTVDVKLFLLTDILLITK-FKKKHIGKYKVIKPPIFLDSIKIHKS-----NTNSFICVCLNDFNCITGLYHFSN 409
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Planmine SMEST
Match: SMESG000023540.1 (SMESG000023540.1)

HSP 1 Score: 143.665 bits (361), Expect = 1.414e-36
Identity = 101/334 (30.24%), Postives = 164/334 (49.10%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSN 1539
             IWEL+ +E  +LKQIHFIV+  +     ++  +FPK+    IF N+ +V   +  FW   +  V +  +    +   R +  GF    +   PY  YC  IS     I+  E  ++ F  +++W  N + SNR  L   +  PF RLT+Y + L  I K  S  DE  E+ + I  VD FV+ +N+ I+   +  KL+   S +  +  IE     + P I  Y   ++T P+Q     E  +R ++ Q +++L++   KT+ VK+ L TD+L+  K  KK    + +++  PI LD + I+ S     N  S     +N F C + +Y  SN
Sbjct:  104 AIWELMVTEQNFLKQIHFIVQIYVVGFEILRPKYFPKVMSEEIFSNLKDVKTVSFEFWKYCIRPVIENYETTRQMFKPRLLKDGFIKIGEILEPYILYCTEISKCRSSISSLEKSNELFAEYIKWAMNFEESNREPLTDHLAKPFLRLTKYKILLQAIQK-YSGIDEKKEIQEMIDAVDTFVSQVNEKIEETNLMKKLQNLNSFIDTYDVIEPLGDDLIPIINQYSKLDLTAPIQYGR--EKVIREILLQGSVKLREGTSKTVDVKLFLLTDILLITK-FKKKHIGKYKVIKPPIFLDSIKIHKS-----NTNSFICVCLNDFNCITGLYHFSN 428
[Close]
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Planmine SMEST
Match: SMESG000023540.1 (SMESG000023540.1)

HSP 1 Score: 144.05 bits (362), Expect = 1.470e-36
Identity = 101/334 (30.24%), Postives = 164/334 (49.10%), Query Frame = 1 
Query:  541 VIWELITSEIVYLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEYMEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITKFELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKECSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTIEEYIKAIFP-IPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKTISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIENDQSIFLAEINQFQCFSTIYKLSN 1539
             IWEL+ +E  +LKQIHFIV+  +     ++  +FPK+    IF N+ +V   +  FW   +  V +  +    +   R +  GF    +   PY  YC  IS     I+  E  ++ F  +++W  N + SNR  L   +  PF RLT+Y + L  I K  S  DE  E+ + I  VD FV+ +N+ I+   +  KL+   S +  +  IE     + P I  Y   ++T P+Q     E  +R ++ Q +++L++   KT+ VK+ L TD+L+  K  KK    + +++  PI LD + I+ S     N  S     +N F C + +Y  SN
Sbjct:  119 AIWELMVTEQNFLKQIHFIVQIYVVGFEILRPKYFPKVMSEEIFSNLKDVKTVSFEFWKYCIRPVIENYETTRQMFKPRLLKDGFIKIGEILEPYILYCTEISKCRSSISSLEKSNELFAEYIKWAMNFEESNREPLTDHLAKPFLRLTKYKILLQAIQK-YSGIDEKKEIQEMIDAVDTFVSQVNEKIEETNLMKKLQNLNSFIDTYDVIEPLGDDLIPIINQYSKLDLTAPIQYGR--EKVIREILLQGSVKLREGTSKTVDVKLFLLTDILLITK-FKKKHIGKYKVIKPPIFLDSIKIHKS-----NTNSFICVCLNDFNCITGLYHFSN 443
The following BLAST results are available for this feature:
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PLEKHG63.464e-3123.96pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG63.485e-3123.96pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG63.485e-3123.96pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG61.382e-2923.71pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG51.031e-2622.96pleckstrin homology and RhoGEF domain containing G... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rhgf-21.727e-1721.73RHo Guanine nucleotide exchange Factor [Source:Un... [more]
rhgf-21.727e-1721.73RHo Guanine nucleotide exchange Factor [Source:Un... [more]
rhgf-21.962e-1721.73RHo Guanine nucleotide exchange Factor [Source:Un... [more]
rhgf-22.858e-1722.01RHo Guanine nucleotide exchange Factor [Source:Un... [more]
prhg-11.788e-1221.87pep chromosome:WBcel235:I:912415:919137:-1 gene:WB... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG426741.588e-2724.56gene:FBgn0261556 transcript:FBtr0332699[more]
CG426749.989e-2724.56gene:FBgn0261556 transcript:FBtr0332698[more]
CG426749.989e-2724.56gene:FBgn0261556 transcript:FBtr0302716[more]
CG426741.761e-2624.56gene:FBgn0261556 transcript:FBtr0302715[more]
CG426742.797e-2624.56gene:FBgn0261556 transcript:FBtr0302713[more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plekhg5a7.788e-3224.17pleckstrin homology domain containing, family G (w... [more]
plekhg5a7.788e-3224.17pleckstrin homology domain containing, family G (w... [more]
plekhg5a7.788e-3224.17pleckstrin homology domain containing, family G (w... [more]
plekhg5a1.002e-3124.17pleckstrin homology domain containing, family G (w... [more]
plekhg5a1.090e-3124.17pleckstrin homology domain containing, family G (w... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PLEKHG56.174e-2424.36pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG56.563e-2424.36pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG57.116e-2424.36pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG57.260e-2424.36pleckstrin homology and RhoGEF domain containing G... [more]
PLEKHG57.451e-2424.36pleckstrin homology and RhoGEF domain containing G... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Plekhg66.747e-3224.02pleckstrin homology domain containing, family G (w... [more]
Plekhg52.076e-2723.87pleckstrin homology domain containing, family G (w... [more]
Plekhg52.272e-2723.87pleckstrin homology domain containing, family G (w... [more]
Plekhg52.444e-2723.87pleckstrin homology domain containing, family G (w... [more]
Plekhg52.761e-2723.87pleckstrin homology domain containing, family G (w... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8R0J1|PKHG6_MOUSE4.720e-3124.02Pleckstrin homology domain-containing family G mem... [more]
sp|Q3KR16|PKHG6_HUMAN1.674e-3023.96Pleckstrin homology domain-containing family G mem... [more]
sp|Q6RFZ7|PKHG5_RAT4.018e-2723.74Pleckstrin homology domain-containing family G mem... [more]
sp|Q66T02|PKHG5_MOUSE2.002e-2623.87Pleckstrin homology domain-containing family G mem... [more]
sp|O94827|PKHG5_HUMAN1.880e-2522.96Pleckstrin homology domain-containing family G mem... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
E9I9G05.368e-3426.63Uncharacterized protein (Fragment) OS=Solenopsis i... [more]
U4UQ616.927e-3428.98DH domain-containing protein (Fragment) OS=Dendroc... [more]
F4WJV84.058e-3326.35Pleckstrin-like proteiny domain-containing family ... [more]
A0A1B6F2M65.062e-3326.22DH domain-containing protein (Fragment) OS=Cuerna ... [more]
A0A158NEM66.397e-3326.35Uncharacterized protein OS=Atta cephalotes OX=1295... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plekhg63.941e-2224.16pleckstrin homology domain containing, family G (w... [more]
plekhg5a3.077e-1723.66pleckstrin homology domain containing, family G (w... [more]
plekhg75.475e-1224.02pleckstrin homology domain containing, family G (w... [more]
PLEKHG13.184e-925.82pleckstrin homology and RhoGEF domain containing G... [more]
tiam1b1.478e-823.53TIAM Rac1 associated GEF 1b [Source:ZFIN;Acc:ZDB-G... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000008020.11.836e-1025.73pep scaffold:Pmarinus_7.0:GL476484:132482:154779:-... [more]
ENSPMAT00000008024.12.971e-1025.35pep scaffold:Pmarinus_7.0:GL476484:132482:154761:-... [more]
ENSPMAT00000003234.13.370e-622.75pep scaffold:Pmarinus_7.0:GL476714:93500:128189:1 ... [more]
dnmbp4.329e-623.32dynamin binding protein [Source:NCBI gene;Acc:1000... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO396084.879e-2724.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496943.519e-1524.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO323282.356e-723.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395951.181e-624.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plekhg5b1.067e-3024.77pleckstrin homology and RhoGEF domain containing G... [more]
plekhg5b1.261e-3024.77pleckstrin homology and RhoGEF domain containing G... [more]
plekhg5b1.500e-3024.77pleckstrin homology and RhoGEF domain containing G... [more]
plekhg64.391e-2323.53pleckstrin homology and RhoGEF domain containing G... [more]
plekhg75.343e-1925.14pleckstrin homology and RhoGEF domain containing G... [more]
back to top
BLAST of Pleckstrin homology and RhoGEF domain containing G6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000049531.10.000e+0100.00SMESG000049531.1[more]
SMESG000023540.17.119e-3728.45SMESG000023540.1[more]
SMESG000023540.11.049e-3630.24SMESG000023540.1[more]
SMESG000023540.11.414e-3630.24SMESG000023540.1[more]
SMESG000023540.11.470e-3630.24SMESG000023540.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030017 ID=SMED30030017|Name=Pleckstrin homology and RhoGEF domain containing G6|organism=Schmidtea mediterranea sexual|type=transcript|length=2150bp
TTCAATTTGATTTAAAATTTTTTCTTTTGAAAAATTTCTTGTAAAAATCG
AAAAAGTCTTTTAAAATATTTTTTTTTGGAAAGATTATTTTTTATTGCTT
TTGTTAACAAAAGATTTTTACAAATGCTCGAATATTTTCCGGAACGTCGA
AAATCGTCGACAGATTTGTTGCCTTTGCCAAAAACGGCATTTTTTCGCCG
ATCTCCGTCTCCATCGAAACGATCGTTTTCCGACTTGTTGAATCCATTTC
AAAAGCGATCGAATGACGATTCGTTGTTCTTTATCGAAAAACAGGAACCG
TTTCCAAAACGACCGGCGAAACTTTTACAATCAACAAAAAGCAAAACCTC
AATGACTAGAAATAACTGTGAAAGCATCACTGAAATTTTACAGAGCTATT
CGGCCGAAAGAGTCTCCAATCCGATTGACAGTGCGTATTCATTCATAGAT
GAGCTGACTACCGAAATGCCCCAGGAAATGTTTCATCGTCAAAATACCGA
ATCAACTAATGAATCCAAAATCCGAAATGAGAAATCTTTCGTGATCTGGG
AACTTATTACGTCGGAAATCGTCTATTTAAAACAAATCCATTTCATTGTT
AAGACTCCTTTACCTATCCTGATTGATATTAAGCAGACGTTCTTTCCAAA
ATTAGATGTATTTTCAATATTTGGTAATATACTTGAGGTTTTTCGGTCAA
ATGTGATCTTTTGGACAGAGTACATGGAAGATGTGTTTCAAATACTAAAA
AATTGTGACAATGTTCCAGACATCAGGCACATGATTTCAGGATTCAATAA
TTTCAGTAAACAGTTCGTTCCTTACAAATCTTATTGTATGAATATTTCGG
CATATTGCGAATACATAACCAAATTTGAGCTGGAGTCGGATTGTTTTCGA
TTATTCTTAGAGTGGTGTAGAAATTCTGATTCCTCCAACCGTCTAGGCCT
GGACACTTTCATTACGATGCCTTTCCAGAGACTAACAAGATATTCTCTAT
TTCTAGACAGAATAATGAAGGAGTGCTCGGACGATGACGAGATCTATGAA
CTTAGTCAAGCAATATCTGAAGTTGACAAGTTTGTAAATAACATAAACAA
ATCTATAAAAGTCAAAGAGATGACATCGAAGCTGCGATATTTTCAAAGTA
TTCTTTGTGGATTCCCGACAATTGAAGAGTATATAAAGGCCATATTTCCA
ATTCCTCCATATCCCGTGTTCAATATGACTTGTCCCATGCAGGTAAAATC
AGAATACGAAAATGAGGTCCGTTGTTTGATTCATCAAGACACGTTGAGAT
TAAAGCAAATCCACAGAAAAACCATTTCAGTCAAAGTGTTGTTATTCACA
GATTTACTAATATTTGCGAAACCCATAAAAAAGAATCAACAGTGCCGTCT
ACAATTATTGGATCATCCAATAGCTCTCGATCAACTGGTGATCTATGACT
CACACGCAATGATCGAAAACGATCAAAGTATATTTCTGGCGGAAATAAAC
CAATTTCAATGCTTTTCAACTATCTACAAGTTATCAAATGATAAATCTTC
TAGTTTTAAAAATCCAGTGAAATATTTCCTGAAAAAGCTGAGTTTTGCCA
AAATGCATTATGAAACAATAATGTTGCAAACGAATCAAACCAATGTTCAC
ATCAATGTGGTCAATTCTGACAGGAATAGTTTGAATAAAGAGGAAGAAAA
CTGTACAAATGAAAGCTCAACGAGTCACCAGAGTGGATCCTCGTCTGTTT
CCGACAATGAAAGTGAAAATGAATATTTAGAACTGTCTAACAAGTCTCTT
TCGTCGAGCTCCTGGATTGATTTAGAAAATAATCTAAACTCCTGCATCAT
TAGTGATCCTTTTATAAACTGTTTCGACTATTTCGACAACACCGACGGCG
GATCTCATAGGAATACTTACCGATATTTGTTACAAAACTGTACCGACAAA
TTTGGGAAGAGAAAACATGACTCTATTCAAAGTTTCGGAGGTGAATCAAC
CTCAACAAAAAATGACCTTGCCATGAACATGTTTAGAACATCATCTTTAG
GAAACAAGCATGTTATTCAATGTAGCACTGAAAATGAATGATTTAATTTT
TGTATAATAATTTATTATTAACAATGATTTAGTCTTTAACACAATTTTGT
back to top

protein sequence of SMED30030017-orf-1

>SMED30030017-orf-1 ID=SMED30030017-orf-1|Name=SMED30030017-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=656bp
MLEYFPERRKSSTDLLPLPKTAFFRRSPSPSKRSFSDLLNPFQKRSNDDS
LFFIEKQEPFPKRPAKLLQSTKSKTSMTRNNCESITEILQSYSAERVSNP
IDSAYSFIDELTTEMPQEMFHRQNTESTNESKIRNEKSFVIWELITSEIV
YLKQIHFIVKTPLPILIDIKQTFFPKLDVFSIFGNILEVFRSNVIFWTEY
MEDVFQILKNCDNVPDIRHMISGFNNFSKQFVPYKSYCMNISAYCEYITK
FELESDCFRLFLEWCRNSDSSNRLGLDTFITMPFQRLTRYSLFLDRIMKE
CSDDDEIYELSQAISEVDKFVNNINKSIKVKEMTSKLRYFQSILCGFPTI
EEYIKAIFPIPPYPVFNMTCPMQVKSEYENEVRCLIHQDTLRLKQIHRKT
ISVKVLLFTDLLIFAKPIKKNQQCRLQLLDHPIALDQLVIYDSHAMIEND
QSIFLAEINQFQCFSTIYKLSNDKSSSFKNPVKYFLKKLSFAKMHYETIM
LQTNQTNVHINVVNSDRNSLNKEEENCTNESSTSHQSGSSSVSDNESENE
YLELSNKSLSSSSWIDLENNLNSCIISDPFINCFDYFDNTDGGSHRNTYR
YLLQNCTDKFGKRKHDSIQSFGGESTSTKNDLAMNMFRTSSLGNKHVIQC
STENE*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005085guanyl-nucleotide exchange factor activity
GO:0005096GTPase activator activity
GO:0005089Rho guanyl-nucleotide exchange factor activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR035899DBL_dom_sf
IPR040181PKHG5/7
IPR000219DH-domain
IPR011993PH-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
GO:0043547positive regulation of GTPase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 140..326
e-value: 1.0E-21
score: 88.1
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 140..325
e-value: 6.7E-29
score: 101.4
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 136..327
score: 23.852
IPR000219Dbl homology (DH) domainCDDcd00160RhoGEFcoord: 137..325
e-value: 3.66926E-22
score: 91.9756
IPR011993PH-like domain superfamilyGENE3DG3DSA:2.30.29.30coord: 373..509
e-value: 1.3E-6
score: 30.3
IPR035899Dbl homology (DH) domain superfamilyGENE3DG3DSA:1.20.900.10coord: 116..344
e-value: 1.2E-35
score: 125.1
IPR035899Dbl homology (DH) domain superfamilySUPERFAMILYSSF48065DBL homology domain (DH-domain)coord: 134..347
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 525..547
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 519..547
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 383..461
IPR040181Pleckstrin homology domain-containing family G member 5/7PANTHERPTHR13217FAMILY NOT NAMEDcoord: 14..597