Rab-GAP TBC domain-containing protein

Overview
NameRab-GAP TBC domain-containing protein
Smed IDSMED30029970
Length (bp)2267
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Rab-GAP TBC domain-containing protein (SMED30029970) t-SNE clustered cells

Violin plots show distribution of expression levels for Rab-GAP TBC domain-containing protein (SMED30029970) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Rab-GAP TBC domain-containing protein (SMED30029970) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Rab-GAP TBC domain-containing protein (SMED30029970) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029970

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30029970SMESG000063156.1 SmedASXL_015076SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30029970SMESG000063156.1 dd_Smed_v4_15291_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30029970SMESG000063156.1 dd_Smed_v4_15291_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30029970SMESG000063156.1 dd_Smed_v4_15291_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30029970SMESG000063156.1 dd_Smed_v6_15291_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30029970SMESG000063156.1 Contig16443newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30029970SMESG000063156.1 Contig16443uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Human
Match: TBC1D19 (TBC1 domain family member 19 [Source:HGNC Symbol;Acc:HGNC:25624])

HSP 1 Score: 412.149 bits (1058), Expect = 1.890e-135
Identity = 207/429 (48.25%), Postives = 294/429 (68.53%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP-FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            P      +K+   Y+ +AQ SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N +     + +  ++  + GL+Q+PL++K I EL+  F EL +   Q+G+DD  ++    FENE   + + +L  +++AA Q++ + G     R ++W  I NI+       YY QLK NV ++DLL+DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  ++ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY R+F +LHSIS  P GI+SLC+LFE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   80 PAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYE-----NGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 503
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Human
Match: TBC1D19 (TBC1 domain family member 19 [Source:HGNC Symbol;Acc:HGNC:25624])

HSP 1 Score: 407.912 bits (1047), Expect = 9.958e-135
Identity = 205/415 (49.40%), Postives = 287/415 (69.16%), Query Frame = 1 
Query:  307 QAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            QA  SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N +     + +  ++  + GL+Q+PL++K I EL+  F EL +   Q+G+DD     +P   FENE   + + +L  +++AA Q++ + G     R ++W  I NI+       YY QLK NV ++DLL+DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  ++ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY R+F +LHSIS  P GI+SLC+LFE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   31 QAWGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYE-----NGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDD--STQVPPELFENEHVRIGQKVLAEQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 438
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Human
Match: TBC1D19 (TBC1 domain family member 19 [Source:HGNC Symbol;Acc:HGNC:25624])

HSP 1 Score: 167.162 bits (422), Expect = 4.045e-46
Identity = 90/222 (40.54%), Postives = 133/222 (59.91%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP-FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLF 921
            P      +K+   Y+ +AQ SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N +     + +  ++  + GL+Q+PL++K I EL+  F EL +   Q+G+DD  ++    FENE   + + +L  +++AA Q++ + G     R ++W  I NI+       YY QLK NV ++DLL+DSL++
Sbjct:   49 PAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYE-----NGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIY 265
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Human
Match: TBC1D19 (TBC1 domain family member 19 [Source:HGNC Symbol;Acc:HGNC:25624])

HSP 1 Score: 149.443 bits (376), Expect = 2.143e-40
Identity = 83/200 (41.50%), Postives = 118/200 (59.00%), Query Frame = 1 
Query:  307 QAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYD 897
            QA  SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N +     + +  ++  + GL+Q+PL++K I EL+  F EL +   Q+G+D  D   +P   FENE   + + +L  +++AA Q++ + G     R ++W  I NI+       YY QLK NV ++D
Sbjct:   31 QAWGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYE-----NGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNIGQLGID--DSTQVPPELFENEHVRIGQKVLAEQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHD 223
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Human
Match: TBC1D19 (TBC1 domain family member 19 [Source:HGNC Symbol;Acc:HGNC:25624])

HSP 1 Score: 65.0846 bits (157), Expect = 3.949e-12
Identity = 31/62 (50.00%), Postives = 39/62 (62.90%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELST 444
            P      +K+   Y+ +AQ SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T
Sbjct:   48 PAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGT 109
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Fly
Match: CG7742 (gene:FBgn0031690 transcript:FBtr0342940)

HSP 1 Score: 333.569 bits (854), Expect = 1.199e-106
Identity = 174/428 (40.65%), Postives = 255/428 (59.58%), Query Frame = 1 
Query:  265 LLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPL-VKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQ-LENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            L+  +V D   YL +A V W++R+ KS+N+MC E ++PL  + R   + ++   KW ELS    +  + RPVYAPKD LEVL+ LK       P  ++E+ + +  W    I L +K++ ELR  +++L      +GV D+       + +R      ILE+R+A  CQ+F K GC     R  +W ++ +  +      Y+ +L+  V+  D ++D L+F +++LTA+NDD YFVFED LYQ+LL FSRDT +    E  T       V+ K+         PPSG++PFHG  M   P CY  D PV LY  F+  Y RY H+L +I+  PQGI+SLC+LFE  LQ+ EP+L+ + R + IQP+R+ FKW+MR FSG L  DQ+L+LWD I+G++SLE+L L AI ILSFRK ++M V +  + E 
Sbjct:   21 LVKPTVSDPLGYLKRAGVLWDRRVRKSLNAMCTELKVPLHGQPRISADREDFMAKWNELSNYNMDLANYRPVYAPKDLLEVLLSLK------GPAKTTENTDQIPQWEFSHIALPVKNLFELRAHYADLLRSDSYLGVPDLT-----VQCQR------ILEARHAPMCQQFLKKGCTPAPYRGALWASVLDSKLHDYDIEYWQKLRNAVWTTDHIVDKLVFKDIQLTASNDDQYFVFEDVLYQVLLCFSRDTDIGGCVEYET-----FPVKGKTYEG------PPSGVVPFHGICMFAAPFCYLYDSPVSLYYTFRAFYIRYCHRLTTINTHPQGIVSLCLLFEKLLQTYEPQLWSHFRELQIQPLRVVFKWLMRAFSGHLPPDQLLVLWDLILGFDSLEILPLFAIIILSFRKESIMQVASLDSIEA 420
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Fly
Match: CG7742 (gene:FBgn0031690 transcript:FBtr0346461)

HSP 1 Score: 333.183 bits (853), Expect = 1.606e-105
Identity = 173/424 (40.80%), Postives = 253/424 (59.67%), Query Frame = 1 
Query:  277 SVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPL-VKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQ-LENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +V D   YL +A V W++R+ KS+N+MC E ++PL  + R   + ++   KW ELS    +  + RPVYAPKD LEVL+ LK       P  ++E+ + +  W    I L +K++ ELR  +++L      +GV D+       + +R      ILE+R+A  CQ+F K GC     R  +W ++ +  +      Y+ +L+  V+  D ++D L+F +++LTA+NDD YFVFED LYQ+LL FSRDT +    E  T       V+ K+         PPSG++PFHG  M   P CY  D PV LY  F+  Y RY H+L +I+  PQGI+SLC+LFE  LQ+ EP+L+ + R + IQP+R+ FKW+MR FSG L  DQ+L+LWD I+G++SLE+L L AI ILSFRK ++M V +  + E 
Sbjct:   93 TVSDPLGYLKRAGVLWDRRVRKSLNAMCTELKVPLHGQPRISADREDFMAKWNELSNYNMDLANYRPVYAPKDLLEVLLSLK------GPAKTTENTDQIPQWEFSHIALPVKNLFELRAHYADLLRSDSYLGVPDLT-----VQCQR------ILEARHAPMCQQFLKKGCTPAPYRGALWASVLDSKLHDYDIEYWQKLRNAVWTTDHIVDKLVFKDIQLTASNDDQYFVFEDVLYQVLLCFSRDTDIGGCVEYET-----FPVKGKTYEG------PPSGVVPFHGICMFAAPFCYLYDSPVSLYYTFRAFYIRYCHRLTTINTHPQGIVSLCLLFEKLLQTYEPQLWSHFRELQIQPLRVVFKWLMRAFSGHLPPDQLLVLWDLILGFDSLEILPLFAIIILSFRKESIMQVASLDSIEA 488
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Fly
Match: CG7742 (gene:FBgn0031690 transcript:FBtr0342941)

HSP 1 Score: 333.183 bits (853), Expect = 1.606e-105
Identity = 173/424 (40.80%), Postives = 253/424 (59.67%), Query Frame = 1 
Query:  277 SVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPL-VKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQ-LENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +V D   YL +A V W++R+ KS+N+MC E ++PL  + R   + ++   KW ELS    +  + RPVYAPKD LEVL+ LK       P  ++E+ + +  W    I L +K++ ELR  +++L      +GV D+       + +R      ILE+R+A  CQ+F K GC     R  +W ++ +  +      Y+ +L+  V+  D ++D L+F +++LTA+NDD YFVFED LYQ+LL FSRDT +    E  T       V+ K+         PPSG++PFHG  M   P CY  D PV LY  F+  Y RY H+L +I+  PQGI+SLC+LFE  LQ+ EP+L+ + R + IQP+R+ FKW+MR FSG L  DQ+L+LWD I+G++SLE+L L AI ILSFRK ++M V +  + E 
Sbjct:   93 TVSDPLGYLKRAGVLWDRRVRKSLNAMCTELKVPLHGQPRISADREDFMAKWNELSNYNMDLANYRPVYAPKDLLEVLLSLK------GPAKTTENTDQIPQWEFSHIALPVKNLFELRAHYADLLRSDSYLGVPDLT-----VQCQR------ILEARHAPMCQQFLKKGCTPAPYRGALWASVLDSKLHDYDIEYWQKLRNAVWTTDHIVDKLVFKDIQLTASNDDQYFVFEDVLYQVLLCFSRDTDIGGCVEYET-----FPVKGKTYEG------PPSGVVPFHGICMFAAPFCYLYDSPVSLYYTFRAFYIRYCHRLTTINTHPQGIVSLCLLFEKLLQTYEPQLWSHFRELQIQPLRVVFKWLMRAFSGHLPPDQLLVLWDLILGFDSLEILPLFAIIILSFRKESIMQVASLDSIEA 488
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Fly
Match: CG7742 (gene:FBgn0031690 transcript:FBtr0079092)

HSP 1 Score: 333.183 bits (853), Expect = 1.606e-105
Identity = 173/424 (40.80%), Postives = 253/424 (59.67%), Query Frame = 1 
Query:  277 SVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPL-VKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQ-LENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +V D   YL +A V W++R+ KS+N+MC E ++PL  + R   + ++   KW ELS    +  + RPVYAPKD LEVL+ LK       P  ++E+ + +  W    I L +K++ ELR  +++L      +GV D+       + +R      ILE+R+A  CQ+F K GC     R  +W ++ +  +      Y+ +L+  V+  D ++D L+F +++LTA+NDD YFVFED LYQ+LL FSRDT +    E  T       V+ K+         PPSG++PFHG  M   P CY  D PV LY  F+  Y RY H+L +I+  PQGI+SLC+LFE  LQ+ EP+L+ + R + IQP+R+ FKW+MR FSG L  DQ+L+LWD I+G++SLE+L L AI ILSFRK ++M V +  + E 
Sbjct:   93 TVSDPLGYLKRAGVLWDRRVRKSLNAMCTELKVPLHGQPRISADREDFMAKWNELSNYNMDLANYRPVYAPKDLLEVLLSLK------GPAKTTENTDQIPQWEFSHIALPVKNLFELRAHYADLLRSDSYLGVPDLT-----VQCQR------ILEARHAPMCQQFLKKGCTPAPYRGALWASVLDSKLHDYDIEYWQKLRNAVWTTDHIVDKLVFKDIQLTASNDDQYFVFEDVLYQVLLCFSRDTDIGGCVEYET-----FPVKGKTYEG------PPSGVVPFHGICMFAAPFCYLYDSPVSLYYTFRAFYIRYCHRLTTINTHPQGIVSLCLLFEKLLQTYEPQLWSHFRELQIQPLRVVFKWLMRAFSGHLPPDQLLVLWDLILGFDSLEILPLFAIIILSFRKESIMQVASLDSIEA 488
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Zebrafish
Match: tbc1d19 (TBC1 domain family, member 19 [Source:ZFIN;Acc:ZDB-GENE-040426-1265])

HSP 1 Score: 428.328 bits (1100), Expect = 5.196e-142
Identity = 198/424 (46.70%), Postives = 293/424 (69.10%), Query Frame = 1 
Query:  280 VKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
             K+   Y+ +AQ SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T   +  + RPVYAPKDFLEVLI L+  N + S   + + +     WGL+Q+ L +  I ++R  ++EL +   Q+G+DD    ++P   FE+E  ++ K ++  +++AA Q++++ GC    R ++W  I N         +Y QLK  V  ++LL+D+L++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDT++L+ F  ++ASP    ++ KS ++Q ++ YPP+G++PFHGFSM V P+C+  ++P +LY +F+EMY RYF +LHSIS  P GI+SLC+ FE  LQ+  P+LF++LR +G QP+R+AFKWI+R FSG+L+ DQ+LLLWDRI+GY SLE+++++A A+ +FR  NLM V +  +AE 
Sbjct:   87 TKEPLAYMLKAQASWEKRILKSLNSMCTELGIPLARKRPVMEQKELTNKWNEMGTDEPDLSNFRPVYAPKDFLEVLIGLRNPNTERSDDLTVKSH-----WGLIQVSLNVHDIPQMRETYAELGLSYGQLGIDD--HTHVPPDLFESEHIHIGKKVVSEQDSAAAQQYSRQGCPTGLRAQLWSLILNTTNDPEDITHYEQLKARVIHHNLLVDNLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTAVLEHFNYNSASPPKSCIQSKSGSEQCAVVYPPNGVIPFHGFSMYVAPLCFLYNEPSKLYSVFREMYIRYFFRLHSISSHPSGIVSLCLQFERLLQAHLPQLFYHLREIGAQPLRIAFKWIVRAFSGYLSTDQLLLLWDRILGYNSLEIVAVLATAVFAFRAENLMEVTSLASAEA 503
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Xenopus
Match: cyp39a1 (cytochrome P450 family 39 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-945546])

HSP 1 Score: 424.861 bits (1091), Expect = 1.011e-140
Identity = 214/424 (50.47%), Postives = 291/424 (68.63%), Query Frame = 1 
Query:  280 VKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +K+   Y+ +AQ SWEKR++KS+NSMC E  I L +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N  I      +  N+  + GL+Q+PL+IK I ELR  F EL++   Q+GVDD     +P   FENE  +L K +L   ++AA Q+F + GC    R  +W  I NI+       YY QLK NV ++DLL DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  S+ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY RYF +LHSIS    GILSLC++FE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY+SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   69 IKEPLTYMRKAQASWEKRVIKSLNSMCTELNIQLARKRPLNEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYDIG-----DQGNYKSHLGLIQVPLKIKDIPELRDFFQELSLNTGQLGVDD--STQVPPELFENEHLSLGKKVLAGHDSAAAQQFVRQGCPTSLRADLWALILNISNQPEDMLYYEQLKSNVIQHDLLSDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLAHFSYSSASPPKSYIRGKLGLEEFAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQVFREMYVRYFFRLHSISSHVSGILSLCLMFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYDSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 485
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Xenopus
Match: cyp39a1 (cytochrome P450 family 39 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-945546])

HSP 1 Score: 422.935 bits (1086), Expect = 1.707e-140
Identity = 214/424 (50.47%), Postives = 291/424 (68.63%), Query Frame = 1 
Query:  280 VKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +K+   Y+ +AQ SWEKR++KS+NSMC E  I L +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N  I      +  N+  + GL+Q+PL+IK I ELR  F EL++   Q+GVDD     +P   FENE  +L K +L   ++AA Q+F + GC    R  +W  I NI+       YY QLK NV ++DLL DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  S+ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY RYF +LHSIS    GILSLC++FE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY+SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   33 IKEPLTYMRKAQASWEKRVIKSLNSMCTELNIQLARKRPLNEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYDIG-----DQGNYKSHLGLIQVPLKIKDIPELRDFFQELSLNTGQLGVDD--STQVPPELFENEHLSLGKKVLAGHDSAAAQQFVRQGCPTSLRADLWALILNISNQPEDMLYYEQLKSNVIQHDLLSDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLAHFSYSSASPPKSYIRGKLGLEEFAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQVFREMYVRYFFRLHSISSHVSGILSLCLMFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYDSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 449
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Xenopus
Match: cyp39a1 (cytochrome P450 family 39 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-945546])

HSP 1 Score: 423.32 bits (1087), Expect = 2.434e-140
Identity = 214/424 (50.47%), Postives = 291/424 (68.63%), Query Frame = 1 
Query:  280 VKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +K+   Y+ +AQ SWEKR++KS+NSMC E  I L +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N  I      +  N+  + GL+Q+PL+IK I ELR  F EL++   Q+GVDD     +P   FENE  +L K +L   ++AA Q+F + GC    R  +W  I NI+       YY QLK NV ++DLL DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  S+ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY RYF +LHSIS    GILSLC++FE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY+SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   52 IKEPLTYMRKAQASWEKRVIKSLNSMCTELNIQLARKRPLNEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYDIG-----DQGNYKSHLGLIQVPLKIKDIPELRDFFQELSLNTGQLGVDD--STQVPPELFENEHLSLGKKVLAGHDSAAAQQFVRQGCPTSLRADLWALILNISNQPEDMLYYEQLKSNVIQHDLLSDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLAHFSYSSASPPKSYIRGKLGLEEFAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQVFREMYVRYFFRLHSISSHVSGILSLCLMFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYDSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 468
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Xenopus
Match: cyp39a1 (cytochrome P450 family 39 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-945546])

HSP 1 Score: 410.994 bits (1055), Expect = 1.598e-135
Identity = 207/421 (49.17%), Postives = 284/421 (67.46%), Query Frame = 1 
Query:  280 VKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +K+   Y+ +AQ SWEKR++KS+NSMC E  I L +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N  I      +  N+  + GL+Q+PL+IK I ELR  F EL++   Q+GVDD  ++              +L   ++AA Q+F + GC    R  +W  I NI+       YY QLK NV ++DLL DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  S+ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY RYF +LHSIS    GILSLC++FE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY+SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   69 IKEPLTYMRKAQASWEKRVIKSLNSMCTELNIQLARKRPLNEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYDIG-----DQGNYKSHLGLIQVPLKIKDIPELRDFFQELSLNTGQLGVDDSTQV------------PPVLAGHDSAAAQQFVRQGCPTSLRADLWALILNISNQPEDMLYYEQLKSNVIQHDLLSDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLAHFSYSSASPPKSYIRGKLGLEEFAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQVFREMYVRYFFRLHSISSHVSGILSLCLMFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYDSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 472
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Mouse
Match: Tbc1d19 (TBC1 domain family, member 19 [Source:MGI Symbol;Acc:MGI:1914499])

HSP 1 Score: 402.519 bits (1033), Expect = 6.967e-132
Identity = 207/429 (48.25%), Postives = 294/429 (68.53%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP-FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            P      +K+   Y+ +AQ SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N +     + +  ++  + GL+Q+PL++K I EL+  F EL +   Q+G+DD  ++    FENE   + + +L  +++AA Q++ + G     R ++W  I NI+       YY QLK NV ++DLL+DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  ++ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY R+F +LHSIS  P GI+SLC+LFE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   80 PSAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPAMEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYE-----NGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNTGQLGIDDSTQVPPELFENEHVRIGQKVLAQQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDILYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLGHFAYNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPYKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 503
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BLAST of Rab-GAP TBC domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8N5T2|TBC19_HUMAN (TBC1 domain family member 19 OS=Homo sapiens OX=9606 GN=TBC1D19 PE=1 SV=2)

HSP 1 Score: 412.149 bits (1058), Expect = 9.075e-135
Identity = 207/429 (48.25%), Postives = 294/429 (68.53%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP-FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            P      +K+   Y+ +AQ SWEKRILKS+NSMC E  IPL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI L+  N +     + +  ++  + GL+Q+PL++K I EL+  F EL +   Q+G+DD  ++    FENE   + + +L  +++AA Q++ + G     R ++W  I NI+       YY QLK NV ++DLL+DSL++ +VKLTA+NDD YFVFEDYLYQ+LL FSRDTS+L  F  ++ASP    +R K   ++ ++FYPP+G++PFHGFSM V P+C+   +P +LY +F+EMY R+F +LHSIS  P GI+SLC+LFE  LQ+  P+LF++LR +G QP+R++FKW++R FSG+LA DQ+LLLWDRI+GY SLE+L+++A A+ +FR  NLM V +  AAE 
Sbjct:   80 PAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYE-----NGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEA 503
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. TrEMBL
Match: A0A1S3K7S8 (TBC1 domain family member 19 OS=Lingula unguis OX=7574 GN=LOC106179541 PE=4 SV=1)

HSP 1 Score: 456.447 bits (1173), Expect = 1.686e-149
Identity = 213/430 (49.53%), Postives = 307/430 (71.40%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAE 1539
            PK     +K+   Y+ +AQ +W+KRI+KS+NSMC E  +PL +KR++K+ KE+   W EL T   +  + RPVYAPKDFLEVL+ L+  N       S E +++   WG++Q+PLRI+SI ELR++F+E++I Q Q GVDD    +IP   F+N+R  LAK +L ++++   QEF K G     R ++W     +++ Q    YY QLK  V ++DLL+DSL++ +VKLTATNDD YFVFEDY+YQ+L PFSRDT +L  F+ S+A+P    +R K   ++ ++ YPP+G++PFHGF+M V P+CY  DDPV LY +F+E+Y RYF +LH IS  PQ I+SLC+LFE+ LQS EP+LF +L+++  QP+R+AFKW++R FSG+L ++QVLLLWDR++ Y SLE+L+++A+AI SFRK+NL+ V T +AAE
Sbjct:   79 PKAGPEHLKEPLTYIRKAQSNWDKRIVKSLNSMCTELGVPLARKRSEKDQKEVIVHWGELGTAAPDLSAFRPVYAPKDFLEVLVGLRNPNAH-----SGEPSSFSSLWGIIQVPLRIRSIMELRLRFNEMSINQCQTGVDD--NPDIPPELFDNDRSKLAKKVLNNKHSPLSQEFLKKGAPPGVRAELWKQTLGVDVDQIDQLYYEQLKSYVVQHDLLVDSLIYKDVKLTATNDDQYFVFEDYIYQVLFPFSRDTQVLDHFKHSSANPPKSYIRGKLGVEEFAVHYPPNGVIPFHGFAMYVAPLCYIYDDPVVLYYVFRELYMRYFFRLHQISSHPQSIVSLCLLFESLLQSQEPQLFLHLKTIQAQPLRIAFKWLIRAFSGYLDSEQVLLLWDRVLAYNSLEILAVLAVAIFSFRKTNLLQVGTASAAE 501
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. TrEMBL
Match: A0A210R0Q6 (TBC1 domain family member 19 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12507 PE=4 SV=1)

HSP 1 Score: 451.825 bits (1161), Expect = 8.836e-148
Identity = 212/427 (49.65%), Postives = 304/427 (71.19%), Query Frame = 1 
Query:  271 TNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
             + +K+   YL +AQ +WEKRILKS+NSMC E  +PL +KR +KE ++I  +WTEL T   +   IRPVYAPKDFLEV+I L   N          H      WG++Q+PL++KSI +LR+Q+S++AI Q Q G+DD    +IP   FE+++  + K ++ + +    QEF+K GC    R  +W  +  + I +    YY QLK NV ++DLL+DSLL+ +VKLTATNDD YFVFED+LYQ+LLPFSRDT +LK F  ++A+P    +R K   ++ ++ YPP+G++PFHGF+M V P+CY  ++PV LY +FKE+Y RYF +LHSIS  PQGIL++ +LFE+ LQ  EPEL+F+L++VG  P++++FKW++R FSG+L++DQVLLLWDRI+ + SLE+L+++A+AI SFRK+NLM V++  AAE 
Sbjct:   83 ADHMKEPLLYLRKAQQNWEKRILKSLNSMCTELNMPLARKRPEKEQRDIIHRWTELGTDGPDLTQIRPVYAPKDFLEVIIGLSNPNYHNGDAPGFHHL-----WGIVQVPLKVKSINKLRLQYSDMAINQGQSGIDDFG--DIPPELFESDKMKIGKKVVNACHGPLAQEFSKKGCPTCLRATLWCQMLGVEIDEEDILYYEQLKVNVQQHDLLVDSLLYKDVKLTATNDDQYFVFEDFLYQVLLPFSRDTCVLKHFAQNSATPPKSYIRGKMGQEEYAVVYPPNGVIPFHGFAMYVAPLCYVFNEPVCLYYVFKELYCRYFFRLHSISSHPQGILAISLLFESLLQIHEPELYFHLKTVGCHPLKISFKWLVRAFSGYLSSDQVLLLWDRILAHSSLEILAVLAVAIFSFRKTNLMKVQSYNAAEA 502
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. TrEMBL
Match: R7T7D7 (Rab-GAP TBC domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_108817 PE=4 SV=1)

HSP 1 Score: 449.514 bits (1155), Expect = 2.680e-147
Identity = 213/434 (49.08%), Postives = 310/434 (71.43%), Query Frame = 1 
Query:  280 VKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLK---IGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKI-NIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQ---------GILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            +K+ ++Y+ +AQ +WEKRILKS+NSMC E  +PL +KR +KE K++  +W EL T   +    RPVYAPKDFLEV+  LK   + +C  +  +S         WG++Q P+ +K + +LR+Q+SE+AI Q Q G+DD  ++ +  FE +R  LA+ +L ++ A A QEFAK G  L +R ++W  I N+ +      YY QLK  V ++DLL+DSL++ +VKLTATNDD YFVFEDYLYQ+LLPFSRDT++L+ F  S+ASPA   +R K   D+ ++ YPP+G++PFHGFSM V P+CY  +D + LY +F+EMY+RYF +LH++S  PQ         GI+SLC+ FE  LQ+ E  LFF+L+S+G+QP+RLAFKW++R FSG+L+++QVLLLWDRI+ ++SLE+L ++A+AI +FRK+NL+ V+T +A+E 
Sbjct:   42 IKEPNSYIRRAQANWEKRILKSLNSMCTELSVPLARKRPEKEQKDMLGRWAELGTDEPDLSQFRPVYAPKDFLEVIASLKNPNVVDCGDNTVSSCA-------WGIIQAPVYVKDLHQLRLQYSEMAINQCQSGIDDGPELPSEVFEADRAKLARKVLAAKLAPATQEFAKKGIPLSHRAQMWSQILNVEVDDVDILYYEQLKTGVLQHDLLVDSLIYKDVKLTATNDDQYFVFEDYLYQVLLPFSRDTTILQHFNYSSASPAKSYIRGKLGVDEFAVNYPPNGVIPFHGFSMYVCPLCYIYNDIIHLYFVFREMYNRYFFRLHTLSSHPQVSASINSIMGIVSLCLQFERLLQTHEAILFFHLKSIGVQPLRLAFKWLIRAFSGYLSSEQVLLLWDRILAFDSLEILPVLAVAIFTFRKTNLLQVQTFSASEA 468
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BLAST of Rab-GAP TBC domain-containing protein vs. TrEMBL
Match: A0A2T7PP35 (Rab-GAP TBC domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_06475 PE=4 SV=1)

HSP 1 Score: 451.825 bits (1161), Expect = 3.568e-147
Identity = 214/418 (51.20%), Postives = 303/418 (72.49%), Query Frame = 1 
Query:  298 YLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP-FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQI-LLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVN 1545
            Y+ +AQ +WEK+ILKS+NSMC E  IPL KKR ++E K++  +WTEL T   +   IRPVYAPKDFLEV+  L+  N + +  + S  +N+   WG++Q+P+++KSI +LR+Q+SE+A+ Q QIGVDD+  I+   F+ E+  L+  +L +++A   QE+AK GC    R ++W  I  I +T     YY QLK +V ++DLL+D+LL+ +VKLTATNDD YFVFED+LYQ+ LLPFSRDT +LK FE ++ +P    +R K   ++ ++ YPP+G++PFHGF+M V P+CY   D V LY +F+ MY  YF++LHS+S  PQGI++L  LFE  LQ  EPELF +L  +G QP+++AFKW+MR FSGFLA+DQVLLLWDRI+ ++SLE+LS++ +AI  FRK+NLM V T +AAEV+
Sbjct:   91 YIRKAQQNWEKKILKSLNSMCTELNIPLAKKRLEQEQKDMLSRWTELGTDGPDLSQIRPVYAPKDFLEVVTGLQNLNYENALTSGSNFHNF---WGVIQVPVKVKSIDQLRLQYSEMAVNQCQIGVDDVSDISADLFDVEQTRLSNKVLAAKHAPTAQEYAKKGCPTSARGELWCQIMGIEVTDVDILYYGQLKTSVIQHDLLVDNLLYKDVKLTATNDDHYFVFEDFLYQVVLLPFSRDTVVLKHFEHNSTTPPKSYIRGKLGVEEFAVVYPPNGVIPFHGFAMYVAPLCYVYKDVVTLYYVFRHMYMHYFYRLHSLSSHPQGIVALSSLFERLLQMSEPELFQHLVRIGCQPLKIAFKWLMRAFSGFLASDQVLLLWDRILAFDSLEILSVLCVAIFCFRKTNLMKVTTFSAAEVS 505
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BLAST of Rab-GAP TBC domain-containing protein vs. TrEMBL
Match: A0A2C9M6S8 (Rab-GAP TBC domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106059415 PE=4 SV=1)

HSP 1 Score: 449.514 bits (1155), Expect = 8.148e-147
Identity = 208/427 (48.71%), Postives = 304/427 (71.19%), Query Frame = 1 
Query:  277 SVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFN--WGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            S K+   Y+ +AQ  WEK+ILKS+NSMC E  +PL + R++K+ K++  +W+EL     +   IRPVYAPKDFLEVL+ L+      +P +++  N   ++  WGL+Q+ L++K++ ELR+Q+SE+AI   Q G DD+   +IP   FENER  L K ++ + +A   +E++K GC +  R  +W  I  +++    Y YY QLK  V ++DLL+DSLL+ +VKLTATNDD YFVFED+LYQ+LLPFSRD+ +LK F  ++A+P    +R K   ++ ++ YPP+G++PFHGF+M V P+CY  +D V LY +F+ MY  YF +LHS+S  PQGI++L +LFE  LQ+ EPELF++L  VG QP+++AFKW+MR FSGFLA+DQVLLLWDRI+ ++S+E+LS++A+AI SFRK+NL+ V+  + AE 
Sbjct:   84 SEKEPIAYILKAQFVWEKKILKSLNSMCTELTVPLARSRSEKDKKDLAARWSELGVDGPDLSQIRPVYAPKDFLEVLVGLQ------NPNSANTGNMGTYDLPWGLIQVSLKVKTLNELRVQYSEMAITHCQTGTDDLP--DIPPELFENERSKLGKKVIAANHAPTAREYSKRGCPVSMRADLWCQILGVDLQNVDYLYYEQLKSYVLQHDLLVDSLLYKDVKLTATNDDQYFVFEDFLYQVLLPFSRDSVVLKHFVYNSATPPKSYIRGKLGIEEFAVTYPPNGVIPFHGFAMYVAPLCYLYNDVVRLYYVFRHMYVNYFFRLHSVSSHPQGIVALSLLFEKVLQAEEPELFYHLIQVGCQPLKIAFKWLMRAFSGFLASDQVLLLWDRILAFDSMEILSVLAVAIFSFRKTNLLKVQCMSTAEA 502
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Cavefish
Match: tbc1d19 (TBC1 domain family member 19 [Source:NCBI gene;Acc:103030444])

HSP 1 Score: 417.157 bits (1071), Expect = 9.936e-138
Identity = 195/420 (46.43%), Postives = 290/420 (69.05%), Query Frame = 1 
Query:  298 YLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGN--CKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP---FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            Y+ +AQ SWEKRILKS+NSMC E  +PL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI LK  N  C+     +S       +WGL+QI L ++ I ++R  + EL++   Q+G+DD    +IP   FE+E   + K ++  +++AA Q++++ GC    R ++W  I N         +Y QLK  V  +DLL+D+L++ +VKLTA+NDD YFVFED+LYQ+LL FSRDT++L+ F  ++A+P    ++ K+  ++ ++ YPP+G++PFHGFSM V P+C+  ++P  LY +F+EMY RYF +LHSIS  P GI+SLC+ FE  LQ+  P+LF++L+++G QP+R+AFKW++R FSG+L+ DQ+LLLWDRI+GY+SLE+++++A A+ +FR  NLM V +  +AE 
Sbjct:   93 YMRKAQASWEKRILKSLNSMCTELGVPLARKRPVSEQKELTNKWNEMGTDEPDLSKFRPVYAPKDFLEVLISLKNPNYDCREGLTANS-------HWGLIQISLNVRDIPQMREAYPELSLTCSQLGIDD--HAHIPPDLFESEHIRIGKKVVSEQDSAAAQQYSRQGCPTGFRAQLWALILNATNEPEDIMHYEQLKAAVIHHDLLVDNLIYKDVKLTASNDDYYFVFEDFLYQVLLCFSRDTAVLEHFSYNSATPPKSYIQGKTGAEEFTVVYPPNGVIPFHGFSMYVSPLCFLYNEPSRLYSVFREMYVRYFFRLHSISSSPSGIVSLCLQFERLLQNHLPQLFYHLQAIGAQPLRIAFKWMVRAFSGYLSTDQLLLLWDRILGYDSLEIVAVLAAAVFTFRAENLMEVTSLASAEA 503
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Cavefish
Match: tbc1d19 (TBC1 domain family member 19 [Source:NCBI gene;Acc:103030444])

HSP 1 Score: 406.757 bits (1044), Expect = 6.072e-134
Identity = 191/417 (45.80%), Postives = 284/417 (68.11%), Query Frame = 1 
Query:  298 YLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGN--CKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            Y+ +AQ SWEKRILKS+NSMC E  +PL +KR   E KE+  KW E+ T   +    RPVYAPKDFLEVLI LK  N  C+     +S       +WGL+QI L ++ I ++R  + EL++   Q+G+DD    +IP           ++  +++AA Q++++ GC    R ++W  I N         +Y QLK  V  +DLL+D+L++ +VKLTA+NDD YFVFED+LYQ+LL FSRDT++L+ F  ++A+P    ++ K+  ++ ++ YPP+G++PFHGFSM V P+C+  ++P  LY +F+EMY RYF +LHSIS  P GI+SLC+ FE  LQ+  P+LF++L+++G QP+R+AFKW++R FSG+L+ DQ+LLLWDRI+GY+SLE+++++A A+ +FR  NLM V +  +AE 
Sbjct:   93 YMRKAQASWEKRILKSLNSMCTELGVPLARKRPVSEQKELTNKWNEMGTDEPDLSKFRPVYAPKDFLEVLISLKNPNYDCREGLTANS-------HWGLIQISLNVRDIPQMREAYPELSLTCSQLGIDD--HAHIP----------PVVSEQDSAAAQQYSRQGCPTGFRAQLWALILNATNEPEDIMHYEQLKAAVIHHDLLVDNLIYKDVKLTASNDDYYFVFEDFLYQVLLCFSRDTAVLEHFSYNSATPPKSYIQGKTGAEEFTVVYPPNGVIPFHGFSMYVSPLCFLYNEPSRLYSVFREMYVRYFFRLHSISSSPSGIVSLCLQFERLLQNHLPQLFYHLQAIGAQPLRIAFKWMVRAFSGYLSTDQLLLLWDRILGYDSLEIVAVLAAAVFTFRAENLMEVTSLASAEA 490
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Cavefish
Match: tbc1d19 (TBC1 domain family member 19 [Source:NCBI gene;Acc:103030444])

HSP 1 Score: 352.829 bits (904), Expect = 2.023e-113
Identity = 171/421 (40.62%), Postives = 270/421 (64.13%), Query Frame = 1 
Query:  298 YLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVNSLNFL 1560
            Y+ +AQ SWEKRILKS+NSMC E  +PL +KR   E KE+  KW E+ T   E G+ R      ++          +C+     +S       +WGL+QI L ++ I ++R  + EL++   Q+G+DD    +IP           ++  +++AA Q++++ GC    R ++W  I N         +Y QLK  V  +DLL+D+L++ +VKLTA+NDD YFVFED+LYQ+LL FSRDT++L+ F  ++A+P    ++ K+  ++ ++ YPP+G++PFHGFSM V P+C+  ++P  LY +F+EMY RYF +LHSIS  P GI+SLC+ FE  LQ+  P+LF++L+++G QP+R+AFKW++R FSG+L+ DQ+LLLWDRI+GY+SLE+++    ++       L++V     A++++L  +
Sbjct:   90 YMRKAQASWEKRILKSLNSMCTELGVPLARKRPVSEQKELTNKWNEMGT--DEPGNRRSYLKNPNY----------DCREGLTANS-------HWGLIQISLNVRDIPQMREAYPELSLTCSQLGIDD--HAHIP----------PVVSEQDSAAAQQYSRQGCPTGFRAQLWALILNATNEPEDIMHYEQLKAAVIHHDLLVDNLIYKDVKLTASNDDYYFVFEDFLYQVLLCFSRDTAVLEHFSYNSATPPKSYIQGKTGAEEFTVVYPPNGVIPFHGFSMYVSPLCFLYNEPSRLYSVFREMYVRYFFRLHSISSSPSGIVSLCLQFERLLQNHLPQLFYHLQAIGAQPLRIAFKWMVRAFSGYLSTDQLLLLWDRILGYDSLEIVA--GGSVFPVLHKQLLSVCNAVLADLSTLKVM 477
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Sea Lamprey
Match: tbc1d19 (TBC1 domain family, member 19 [Source:ZFIN;Acc:ZDB-GENE-040426-1265])

HSP 1 Score: 283.878 bits (725), Expect = 3.442e-89
Identity = 140/330 (42.42%), Postives = 206/330 (62.42%), Query Frame = 1 
Query:  283 KDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLK---IGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINI-PFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSM-LVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDP 1257
            K+   Y+ +AQ  WEKR++KS+NSMC E  + L +KR+ +E K +  KW+E+ +   +    RPVYAPKDFLEVL+ L+   + N     P           WGL+Q+PL I + ++L   F ELA+ +QQ G++D+  +    FE +R+ LAK +LE+  +   Q FA+ GC    R  +W  I N+++       Y QLK  V + DLL+D+L++ +VKLTA+NDD YFVFED+LYQ+LL FSRDT +L  FE ++A+P+    R K   ++ +  YPPSG++PFHGF+M  V P+C+   +P  LY  F +MY R+F +LHS+S  P
Sbjct:   50 KEPVAYMRRAQAQWEKRVMKSLNSMCTELGVTLCQKRSPEEQKGLLSKWSEMGSDEPDLSRFRPVYAPKDFLEVLVHLQDPEVLNFDPGHPCRP--------WGLVQVPLEISTSEQLSQHFKELALHEQQTGLEDVTPLTSESFEVQREKLAKKVLETDESLLAQHFARKGCPNAQRAALWLLILNVSMGAEEIQKYEQLKSAVVQQDLLVDNLIYKDVKLTASNDDYYFVFEDFLYQVLLCFSRDTKVLSHFEHNSATPSKTYSR-KMGVEEFATVYPPSGVIPFHGFTMYAVAPLCFLYHEPHTLYYAFHQMYVRHFFRLHSVSSHP 370
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Nematostella
Match: EDO40830 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6A8])

HSP 1 Score: 375.941 bits (964), Expect = 3.525e-122
Identity = 188/435 (43.22%), Postives = 279/435 (64.14%), Query Frame = 1 
Query:  283 KDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTL--TKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP--FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAE-----VNSLNFL 1560
            K+   ++ +AQ +WEKRI+KS+NSMC E  +PL +KR+  +   +   +  L      KE   I+PVYAPKDF E L+ ++  N   +P   S  +  +  WGL+Q+ L  K + ELR  F EL       GVDD+   N    FE +   + K ++ + +A A ++FAK GC    R +IW  I  +N+      Y+ QLK  V ++++L+DSL+  ++++TATNDD YFVFED LYQ +L F+RDT++LK F+ S+A+     +R K    + ++ YPP+GI+PFHGFSM   P+CY       +Y +F+EMY+RYF +LH++S  PQGI+SLC+LFE  LQ+ EP L ++L+ VG QP+RL F W++  FSG+L+ DQVLLLWDRI+ Y+SLE+  ++A+AILS+R+SNLM V +  AA+     V++LN +
Sbjct:   88 KEPLAFIRKAQATWEKRIVKSVNSMCTELSLPLARKRSAIDQATMASTFETLGADLNEKEFEKIKPVYAPKDFFEALVAVE--NPNFTPLRKSPSS--IKGWGLVQVNLYTKDLHELRSTFRELEPNTCHCGVDDMTGSNTVENFETDWYKMGKKVVHNGSAMAARQFAKYGCPSGIRGEIWKQILCLNVDDVDLLYFEQLKSYVIQHEMLVDSLVMKDIRITATNDDDYFVFEDLLYQAMLVFTRDTAVLKHFQQSSATAPKSYIRGKLGVQEFAVAYPPNGIMPFHGFSMHAAPLCYVCSHAPGMYFLFREMYTRYFFRLHTMSSHPQGIMSLCLLFENLLQTHEPLLLYHLKEVGAQPLRLVFSWMVYAFSGYLSTDQVLLLWDRILAYDSLELFPVMAMAILSYRRSNLMEVTSLQAAQTVLADVSTLNVI 518
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Medaka
Match: tbc1d19 (TBC1 domain family member 19 [Source:NCBI gene;Acc:101166748])

HSP 1 Score: 398.667 bits (1023), Expect = 8.479e-131
Identity = 191/429 (44.52%), Postives = 287/429 (66.90%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP-FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            P      +K+   Y+ +AQ SWEKR+LKS+NSM  E  +PL + R   E K++  KW E+ T   +    RPVYAPKDFLEVLI L+  N       SSE      +WGL+Q+PL ++ I +LR  +SEL +   Q+G+DD   ++   FEN    + K ++  +++AA Q++++ GC    R  +W    N         +Y QLK  V ++DLL+D L++ +VKLTA+NDD YFVFED+LYQ++L FSRDT++L+ F+ ++A+P    +  K  N++ ++ YPP+G++PFHGFSM V P+C+  ++P +LY +F+ MY RYF +LHSIS  P GI++LC+ FE  LQ+  P+LF++LR +G QP+R+AFKW++R FSG+L+ DQ+LLLWDRI+GY+SLE+++++A A+ +FR  NLM V +  +AE 
Sbjct:   61 PTTPAEHLKEPLAYMRKAQASWEKRVLKSLNSMSTELGVPLARMRPAGEQKDLTNKWNEMGTDEPDLSRFRPVYAPKDFLEVLISLRNPNHD-----SSEDMTVKSHWGLIQVPLNVRDIPQLRQAYSELNLNNGQLGIDDHAHVHPDLFENSYVQIGKKVVVEQDSAAAQQYSRRGCPTGLRSDLWALTLNSTNQPQDVMHYEQLKAGVIQHDLLVDYLIYKDVKLTASNDDYYFVFEDFLYQVMLCFSRDTAVLEHFKYNSATPPKSYIHGKVGNEEFAVLYPPNGVIPFHGFSMYVAPLCFLYNEPSKLYSVFRMMYIRYFFRLHSISSSPSGIVALCLQFERLLQAHLPQLFYHLRQIGAQPLRIAFKWMVRAFSGYLSTDQLLLLWDRILGYDSLEVVAVLAAAVFAFRAENLMEVASLASAEA 484
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Medaka
Match: tbc1d19 (TBC1 domain family member 19 [Source:NCBI gene;Acc:101166748])

HSP 1 Score: 399.053 bits (1024), Expect = 1.074e-130
Identity = 191/429 (44.52%), Postives = 287/429 (66.90%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIP-FENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            P      +K+   Y+ +AQ SWEKR+LKS+NSM  E  +PL + R   E K++  KW E+ T   +    RPVYAPKDFLEVLI L+  N       SSE      +WGL+Q+PL ++ I +LR  +SEL +   Q+G+DD   ++   FEN    + K ++  +++AA Q++++ GC    R  +W    N         +Y QLK  V ++DLL+D L++ +VKLTA+NDD YFVFED+LYQ++L FSRDT++L+ F+ ++A+P    +  K  N++ ++ YPP+G++PFHGFSM V P+C+  ++P +LY +F+ MY RYF +LHSIS  P GI++LC+ FE  LQ+  P+LF++LR +G QP+R+AFKW++R FSG+L+ DQ+LLLWDRI+GY+SLE+++++A A+ +FR  NLM V +  +AE 
Sbjct:   79 PTTPAEHLKEPLAYMRKAQASWEKRVLKSLNSMSTELGVPLARMRPAGEQKDLTNKWNEMGTDEPDLSRFRPVYAPKDFLEVLISLRNPNHD-----SSEDMTVKSHWGLIQVPLNVRDIPQLRQAYSELNLNNGQLGIDDHAHVHPDLFENSYVQIGKKVVVEQDSAAAQQYSRRGCPTGLRSDLWALTLNSTNQPQDVMHYEQLKAGVIQHDLLVDYLIYKDVKLTASNDDYYFVFEDFLYQVMLCFSRDTAVLEHFKYNSATPPKSYIHGKVGNEEFAVLYPPNGVIPFHGFSMYVAPLCFLYNEPSKLYSVFRMMYIRYFFRLHSISSSPSGIVALCLQFERLLQAHLPQLFYHLRQIGAQPLRIAFKWMVRAFSGYLSTDQLLLLWDRILGYDSLEVVAVLAAAVFAFRAENLMEVASLASAEA 502
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Medaka
Match: tbc1d19 (TBC1 domain family member 19 [Source:NCBI gene;Acc:101166748])

HSP 1 Score: 331.643 bits (849), Expect = 5.399e-105
Identity = 177/428 (41.36%), Postives = 268/428 (62.62%), Query Frame = 1 
Query:  259 PKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            P      +K+   Y+ +AQ SWEKR+LKS+NSM  E  +PL + R   E K++  KW E+ T   +    RPVYAPKDFLEVLI L+  N       SSE      +WGL+Q+PL ++ I +LR  +SEL +   Q+G+DD             ++  +++E +++AA Q++++ GC    R  +W    N         +Y QLK  V ++DLL+D L++ +VKLTA+NDD YFVFED+LYQ++L FSRDT++L+ F+ ++A+P    +  K  N++ ++ YPP+G++PFHGFSM V P+C+  ++P +LY +F+ MY RYF +LHSIS       S   +  +TL S E       +  G   +R+AFKW++R FSG+L+ DQ+LLLWDRI+GY+SLE+++++A A+ +FR  NLM V +  +AE 
Sbjct:   81 PTTPAEHLKEPLAYMRKAQASWEKRVLKSLNSMSTELGVPLARMRPAGEQKDLTNKWNEMGTDEPDLSRFRPVYAPKDFLEVLISLRNPNHD-----SSEDMTVKSHWGLIQVPLNVRDIPQLRQAYSELNLNNGQLGIDD-----------HAHVHPVVVE-QDSAAAQQYSRRGCPTGLRSDLWALTLNSTNQPQDVMHYEQLKAGVIQHDLLVDYLIYKDVKLTASNDDYYFVFEDFLYQVMLCFSRDTAVLEHFKYNSATPPKSYIHGKVGNEEFAVLYPPNGVIPFHGFSMYVAPLCFLYNEPSKLYSVFRMMYIRYFFRLHSIS-------SSPSVSSSTLNS-EKTPAELSKFGGADVLRIAFKWMVRAFSGYLSTDQLLLLWDRILGYDSLEVVAVLAAAVFAFRAENLMEVASLASAEA 483
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Planmine SMEST
Match: SMESG000063156.1 (SMESG000063156.1)

HSP 1 Score: 1048.88 bits (2711), Expect = 0.000e+0
Identity = 533/537 (99.26%), Postives = 536/537 (99.81%), Query Frame = 1 
Query:   37 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELXXXXXXXXXXXXXXXXXXPKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVNSLNFLFPALLTLSYALNFCFCFNVIAVHIFILCK 1647
            MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQ+QVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNW+FNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPA ISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVNSLNFLFPALLTLSYALNFCFCFNVIAVHIF+LCK
Sbjct:    1 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQSQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWIFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPAKISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVNSLNFLFPALLTLSYALNFCFCFNVIAVHIFVLCK 537
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Planmine SMEST
Match: SMESG000063156.1 (SMESG000063156.1)

HSP 1 Score: 1047.34 bits (2707), Expect = 0.000e+0
Identity = 531/535 (99.25%), Postives = 534/535 (99.81%), Query Frame = 1 
Query:   37 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELXXXXXXXXXXXXXXXXXXPKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVNSLNFLFPALLTLSYALNFCFCFNVIAVHIFIL 1641
            MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQ+QVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNW+FNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPA ISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVNSLNFLFPALLTLSYALNFCFCFNVIAVHIF+L
Sbjct:    1 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQSQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWIFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPAKISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEVNSLNFLFPALLTLSYALNFCFCFNVIAVHIFVL 535
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Planmine SMEST
Match: SMESG000063156.1 (SMESG000063156.1)

HSP 1 Score: 978.778 bits (2529), Expect = 0.000e+0
Identity = 498/502 (99.20%), Postives = 500/502 (99.60%), Query Frame = 1 
Query:   37 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELXXXXXXXXXXXXXXXXXXPKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQ+QVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNW+FNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPA ISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAE 
Sbjct:    1 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQSQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWIFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPAKISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEA 502
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Planmine SMEST
Match: SMESG000063156.1 (SMESG000063156.1)

HSP 1 Score: 977.237 bits (2525), Expect = 0.000e+0
Identity = 498/501 (99.40%), Postives = 500/501 (99.80%), Query Frame = 1 
Query:   37 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELXXXXXXXXXXXXXXXXXXPKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAE 1539
            MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQ+QVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNW+FNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPA ISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAE
Sbjct:    1 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQSQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWIFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPAKISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAE 501

HSP 2 Score: 55.0694 bits (131), Expect = 1.480e-7
Identity = 26/36 (72.22%), Postives = 29/36 (80.56%), Query Frame = 2 
Query: 2159 IVNVCILFVFQNFNIVGLKKLMRSYKRNKYTETWFR 2266
            ++NV      +NFNIVGLKKLM SYKRNKYTETWFR
Sbjct:  491 LMNVKTQTAAENFNIVGLKKLMGSYKRNKYTETWFR 526
[Close]
BLAST of Rab-GAP TBC domain-containing protein vs. Planmine SMEST
Match: SMESG000063156.1 (SMESG000063156.1)

HSP 1 Score: 953.74 bits (2464), Expect = 0.000e+0
Identity = 485/502 (96.61%), Postives = 491/502 (97.81%), Query Frame = 1 
Query:   37 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELXXXXXXXXXXXXXXXXXXPKLLTNSVKDADNYLFQAQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAAEV 1542
            MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQ+QVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNW+FNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPA ISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSL+A+A+  FRKSNL    +   AE 
Sbjct:    1 MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEILKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQSQVSWEKRILKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAPKDFLEVLIKLKIGNCKISPPTSSEHNNWIFNWGLLQIPLRIKSIQELRIQFSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSGCQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKLTATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPAKISVRVKSSNDQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKLHSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRGFSGFLAADQVLLLWDRIVGYESLEMLSLLAVAVFQFRKSNLFITTSLPIAEA 502
The following BLAST results are available for this feature:
BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TBC1D191.890e-13548.25TBC1 domain family member 19 [Source:HGNC Symbol;A... [more]
TBC1D199.958e-13549.40TBC1 domain family member 19 [Source:HGNC Symbol;A... [more]
TBC1D194.045e-4640.54TBC1 domain family member 19 [Source:HGNC Symbol;A... [more]
TBC1D192.143e-4041.50TBC1 domain family member 19 [Source:HGNC Symbol;A... [more]
TBC1D193.949e-1250.00TBC1 domain family member 19 [Source:HGNC Symbol;A... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
CG77421.199e-10640.65gene:FBgn0031690 transcript:FBtr0342940[more]
CG77421.606e-10540.80gene:FBgn0031690 transcript:FBtr0346461[more]
CG77421.606e-10540.80gene:FBgn0031690 transcript:FBtr0342941[more]
CG77421.606e-10540.80gene:FBgn0031690 transcript:FBtr0079092[more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tbc1d195.196e-14246.70TBC1 domain family, member 19 [Source:ZFIN;Acc:ZDB... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
cyp39a11.011e-14050.47cytochrome P450 family 39 subfamily A member 1 [So... [more]
cyp39a11.707e-14050.47cytochrome P450 family 39 subfamily A member 1 [So... [more]
cyp39a12.434e-14050.47cytochrome P450 family 39 subfamily A member 1 [So... [more]
cyp39a11.598e-13549.17cytochrome P450 family 39 subfamily A member 1 [So... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Tbc1d196.967e-13248.25TBC1 domain family, member 19 [Source:MGI Symbol;A... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1
Match NameE-valueIdentityDescription
sp|Q8N5T2|TBC19_HUMAN9.075e-13548.25TBC1 domain family member 19 OS=Homo sapiens OX=96... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3K7S81.686e-14949.53TBC1 domain family member 19 OS=Lingula unguis OX=... [more]
A0A210R0Q68.836e-14849.65TBC1 domain family member 19 OS=Mizuhopecten yesso... [more]
R7T7D72.680e-14749.08Rab-GAP TBC domain-containing protein (Fragment) O... [more]
A0A2T7PP353.568e-14751.20Rab-GAP TBC domain-containing protein OS=Pomacea c... [more]
A0A2C9M6S88.148e-14748.71Rab-GAP TBC domain-containing protein OS=Biomphala... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tbc1d199.936e-13846.43TBC1 domain family member 19 [Source:NCBI gene;Acc... [more]
tbc1d196.072e-13445.80TBC1 domain family member 19 [Source:NCBI gene;Acc... [more]
tbc1d192.023e-11340.62TBC1 domain family member 19 [Source:NCBI gene;Acc... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tbc1d193.442e-8942.42TBC1 domain family, member 19 [Source:ZFIN;Acc:ZDB... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO408303.525e-12243.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tbc1d198.479e-13144.52TBC1 domain family member 19 [Source:NCBI gene;Acc... [more]
tbc1d191.074e-13044.52TBC1 domain family member 19 [Source:NCBI gene;Acc... [more]
tbc1d195.399e-10541.36TBC1 domain family member 19 [Source:NCBI gene;Acc... [more]
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BLAST of Rab-GAP TBC domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000063156.10.000e+099.26SMESG000063156.1[more]
SMESG000063156.10.000e+099.25SMESG000063156.1[more]
SMESG000063156.10.000e+099.20SMESG000063156.1[more]
SMESG000063156.11.480e-799.40SMESG000063156.1[more]
SMESG000063156.10.000e+096.61SMESG000063156.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029970 ID=SMED30029970|Name=Rab-GAP TBC domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2267bp
TCCGATCTTGATAATTAAAGGTAATTTTAAATTTAGATGGAACGGATTCA
AATCGCAAATAATATTTTTAAATCATTGGATAATAGTGAATTTAAAGTTC
ATTTATATAACAAATTAATTAACTCTTTTAATAAACAATCTTTTCAACCT
GGAAATGATATTTTTTCAAATATCGAAGAAGAAATTCTTAAAGATAGTGA
ACTGAACGAAGAATTTAATAATTTCATATTTTCTGAATCGTTTAAATTTA
TAAATAATCCGAAATTATTAACAAATTCTGTCAAGGATGCTGATAATTAT
CTTTTTCAAGCACAGGTTTCATGGGAAAAACGAATTTTAAAAAGCATTAA
CTCAATGTGCATGGAATTTCAAATTCCTTTAGTAAAAAAGAGAACCGATA
AAGAAATGAAAGAAATACGCGAAAAATGGACAGAATTAAGCACTCTCACA
AAAGAAACTGGATCTATTAGGCCTGTTTATGCACCGAAAGATTTTCTTGA
AGTTTTGATCAAGTTGAAAATTGGTAACTGCAAAATATCGCCACCGACAT
CATCTGAACACAACAATTGGCTTTTTAATTGGGGTTTACTACAGATTCCT
CTTAGAATTAAATCTATACAAGAACTGAGAATTCAATTCAGCGAGTTAGC
TATCGGTCAACAGCAAATTGGTGTAGACGATATTGATAAAATTAATATAC
CATTTGAAAATGAAAGACAAAATTTAGCAAAAATAATACTAGAGTCTAGG
AATGCTGCTGCTTGCCAGGAATTCGCAAAAAGTGGATGTCAGCTCGAAAA
TAGACGGAAAATTTGGTACACCATTTTCAACATCAACATAACACAATCAA
CTTATAATTATTATAACCAATTGAAACAAAATGTCTTTGAATATGATCTA
CTTATTGATTCTTTATTATTCATGGAAGTTAAACTTACAGCTACAAATGA
TGATACCTATTTTGTATTTGAAGATTATCTTTATCAGATCTTATTGCCAT
TTTCTCGGGATACATCATTATTAAAGGTATTTGAAGCAAGTACAGCGTCT
CCCGCAAATATTTCAGTTCGAGTAAAGTCATCCAATGATCAAAGCTCTAT
TTTCTATCCTCCTAGTGGAATTTTACCTTTTCATGGGTTTTCTATGTTGG
TTGTACCAATGTGCTATTTTATTGATGACCCTGTCGAATTATATGTCATG
TTTAAAGAAATGTATTCAAGATATTTTCACAAACTGCATTCAATTAGCGA
TGATCCTCAAGGAATTTTATCACTATGTGTACTTTTTGAAGCTACATTAC
AAAGCCTGGAACCAGAATTGTTTTTTTATCTTCGTTCTGTTGGGATTCAA
CCAATCAGATTGGCTTTCAAATGGATTATGCGAGGTTTTAGTGGGTTTTT
GGCAGCTGATCAGGTGTTACTGCTGTGGGATAGAATCGTTGGTTATGAAT
CTCTTGAGATGTTATCTTTGGTGGCTATAGCCATTCTCAGCTTTAGGAAG
TCTAATTTGATGAACGTTAAAACTCAAACTGCGGCCGAGGTGAACTCATT
AAATTTTTTATTTCCTGCTTTGTTAACCCTATCTTATGCGCTAAATTTTT
GCTTTTGTTTTAATGTGATTGCAGTTCACATTTTTATACTATGTAAATAA
TTGTTCTCATTTGTATCAATGAATATTGAAGAATTTAAAGAAGCGTTAAG
AAGGAAATAACTTTTAACCCTACTTTTCTCGTTAGTTTTTAAGACATTTA
AAACCCTGGGCTTAAATTTTTTTATTTTTTCACTCTCGTGGCAACTAATT
TTATATCGCAGAAAATTAAACCTTTAAATTAATGAAACGCAAATTAATTT
CACTAAATCTTTTTATTATACTAAAATTTATACAAATAAAAACAATTGTA
AAAATAAATACGTATAAAATTAAACGCTTAAATTAATAAGAATATTATAA
CAAAACCTTGATAATTATTTTTAAAATTTTGCAGAATAAATTTTTGGGAA
ATAATGTTTAAAATGGTTTTTTATAGTTAAATTAATGTTAAATTACACTA
AGTTTCGTCGAATGATGTCTCTTATAATATAAGGAAAAATCAAATATTTT
TACTCCACGACGCAATGACAATGAATAAGAGCCACAATAATATAAATAAA
ACTAACCAATCGTAAATGTTTGTATTTTGTTTGTATTTCAGAACTTTAAC
ATAGTGGGTTTGAAAAAGTTAATGAGAAGCTATAAGAGAAATAAATACAC
AGAAACTTGGTTCAGAC
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protein sequence of SMED30029970-orf-1

>SMED30029970-orf-1 ID=SMED30029970-orf-1|Name=SMED30029970-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=538bp
MERIQIANNIFKSLDNSEFKVHLYNKLINSFNKQSFQPGNDIFSNIEEEI
LKDSELNEEFNNFIFSESFKFINNPKLLTNSVKDADNYLFQAQVSWEKRI
LKSINSMCMEFQIPLVKKRTDKEMKEIREKWTELSTLTKETGSIRPVYAP
KDFLEVLIKLKIGNCKISPPTSSEHNNWLFNWGLLQIPLRIKSIQELRIQ
FSELAIGQQQIGVDDIDKINIPFENERQNLAKIILESRNAAACQEFAKSG
CQLENRRKIWYTIFNINITQSTYNYYNQLKQNVFEYDLLIDSLLFMEVKL
TATNDDTYFVFEDYLYQILLPFSRDTSLLKVFEASTASPANISVRVKSSN
DQSSIFYPPSGILPFHGFSMLVVPMCYFIDDPVELYVMFKEMYSRYFHKL
HSISDDPQGILSLCVLFEATLQSLEPELFFYLRSVGIQPIRLAFKWIMRG
FSGFLAADQVLLLWDRIVGYESLEMLSLVAIAILSFRKSNLMNVKTQTAA
EVNSLNFLFPALLTLSYALNFCFCFNVIAVHIFILCK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR042507TBC1D19
IPR035969Rab-GTPase_TBC_sf
IPR000195Rab-GTPase-TBC_dom
Vocabulary: molecular function
TermDefinition
GO:0005096GTPase activator activity
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0043547positive regulation of GTPase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.472.80coord: 404..508
e-value: 1.9E-14
score: 55.5
NoneNo IPR availableTMHMMTMhelixcoord: 513..535
IPR000195Rab-GTPase-TBC domainPFAMPF00566RabGAP-TBCcoord: 367..491
e-value: 2.9E-10
score: 40.2
IPR000195Rab-GTPase-TBC domainPROSITEPS50086TBC_RABGAPcoord: 250..471
score: 13.211
IPR042507TBC1 domain family member 19PANTHERPTHR16110FAMILY NOT NAMEDcoord: 7..501
IPR035969Rab-GTPase-TBC domain superfamilySUPERFAMILYSSF47923Ypt/Rab-GAP domain of gyp1pcoord: 406..494