Pre-mRNA-processing factor 40

Query:  616 PIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYL 1854
            P  +   + TKEE ++ ++ +LKE  VP NA+WE A+KMI  DPRY  L K ++KKQ FN YK Q +K+E+EEAR + K+AKE  ++FL NH K++S   Y+KA+ +  +   W A+ ERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T+ TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F +F+DELHE G+L S+S W +LY  IS D RF  ML QPGST LDLFKFYV +LK+R+  EK+I+K+IL+D+ F  + NT+ E F+ +I   +R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK  +  I+    WE++ ++      F+ + LES+R + +K+++
Sbjct:  356 PAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFM 770          

Query:  148 LPP----TSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENN--TTDKPKESSAIDEAIKATLGSMPSS 549
            LPP      V     +  +  WTEH + DGRTYYYN  TKQSTWEKPD+LKTPAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E   Y N   + + I ++N     K +ESS  +E    +   +P++
Sbjct:   98 LPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE--GYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTT 235          

Query:  631 VVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSSREH 1956
            + +  +E+ ++ ++ +L++  VP NA+WE A+KM+  DPRY  L K ++KKQ FN YK QR+K+E+EEARLR K+AK+ L+ FL  H +++S   YR+A+    +   W  VPERDR+E+Y+D L  + K+EKE+AK LR+RNI+    ILD M ++ F+TTW +AQ+ L++NP F +D  LQ+MDKEDALICFEEHIR LE++ EEE+ER + R +R QRKNREAF  F+DELHE G+L S+S W +LY  +S D RF  ML QPGSTPLDLFKFYV ELK+RF  EK+I+K+IL+DR F  + NT+ E F  VI  D+R   LD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  F+ ML+     ++   +WEEV ++      F+ + LES+R++ ++E+L  + +  +   +    + RKH    K+    R H
Sbjct:  293 LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLETECQHLHT----KGRKHGRKGKKHHHKRSH 732          

Query:  112 PLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL 426
            P+T +   P +    ++V  + P  P   W+EH+A DGR YYYN   KQS WEKP  LK+ AE +LS+CPWKE+KS+ GK YYYN  +++S W +P +L + E L
Sbjct:   94 PVT-AATAPGADTASSAVAGTGP--PRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVL 195          

Query:  631 VVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSSREH 1956
            + +  +E+ ++ ++ +L++  VP NA+WE A+KM+  DPRY  L K ++KKQ FN YK QR+K+E+EEARLR K+AK+ L+ FL  H +++S   YR+A+    +   W  VPERDR+E+Y+D L  + K+EKE+AK LR+RNI+    ILD M ++ F+TTW +AQ+ L++NP F +D  LQ+MDKEDALICFEEHIR LE++ EEE+ER + R +R QRKNREAF  F+DELHE G+L S+S W +LY  +S D RF  ML QPGSTPLDLFKFYV ELK+RF  EK+I+K+IL+DR F  + NT+ E F  VI  D+R   LD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  F+ ML+     ++   +WEEV ++      F+ + LES+R++ ++E+L  +    +++      + RKH    K+    R H
Sbjct:  271 LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVL---EQTECQHLHTKGRKHGRKGKKHHHKRSH 711          

Query:  112 PLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL 426
            P+T +   P +    ++V  + P  P   W+EH+A DGR YYYN   KQS WEKP  LK+ AE +LS+CPWKE+KS+ GK YYYN  +++S W +P +L + E L
Sbjct:   72 PVT-AATAPGADTASSAVAGTGP--PRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVL 173          

Query:  631 VVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSSREH 1956
            + +  +E+ ++ ++ +L++  VP NA+WE A+KM+  DPRY  L K ++KKQ FN YK QR+K+E+EEARLR K+AK+ L+ FL  H +++S   YR+A+    +   W  VPERDR+E+Y+D L  + K+EKE+AK LR+RNI+    ILD M ++ F+TTW +AQ+ L++NP F +D  LQ+MDKEDALICFEEHIR LE++ EEE+ER + R +R QRKNREAF  F+DELHE G+L S+S W +LY  +S D RF  ML QPGSTPLDLFKFYV ELK+RF  EK+I+K+IL+        NT+ E F  VI  D+R   LD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  F+ ML+     ++   +WEEV ++      F+ + LES+R++ ++E+L  +    +++      + RKH    K+    R H
Sbjct:  265 LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILK-------VNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVL---EQTECQHLHTKGRKHGRKGKKHHHKRSH 698          

Query:  112 PLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL 426
            P+T +   P +    ++V  + P  P   W+EH+A DGR YYYN   KQS WEKP  LK+ AE +LS+CPWKE+KS+ GK YYYN  +++S W +P +L + E L
Sbjct:   66 PVT-AATAPGADTASSAVAGTGP--PRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVL 167          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKP 489
            WTEH + DGRTYYYN  TKQSTWEKPD+LKTPAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E +      +   E    +T   P
Sbjct:  139 WTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEAMIKAEESSKQEECTTTSTAPVP 235          

Query:   91 NYQFTLPPLTHSYPVPTSYLPPTSV---QNSLPTLP--------------------EQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECP----WKEFKSEQGKIYYYNTVTQQSVWQKPP--ELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEY 1851
            N +F +PP+     VP   +P  SV     + PT P                    E  W+ H  + G  YY+N +TKQ++W KPD LKTP E+  S  P    WKEF S+ GK YYYNT+T+++ W KP   E+ + E+       T D  +       + K  S +D+A+KATL SMP+        ++ S  DEV          ++  R  E   E  R    +  +  N  W+ AVK I  DPR++ L K ++KKQ+FN +K QR K+ER+E RL IKK+KEDLEKFL  H K+  ++ Y+KA  + S  P W AV + DR+EI+ D +  + +R+KE+ +  RKR+I  F+ +L  M  +T+KTTW +AQRIL ENP+F E +DL  MDKEDAL  FE+HI+  EK+H+EEKE+E++RL+R QRK RE + + ++ LH++G+LTS+S+W  L+ IIS D RF  ML QPGS+PLDLFKF+V +LK ++++++R++KEIL ++       T    F   +   E+G  +D GN+++ Y SLIE+AES  K   KE L+++++ E  F+ +LK H++     W  +  K+   + +  +E + +R   +  Y
Sbjct:   25 NQRFGMPPVGSIAQVPLLQMPTHSVVAPHVAAPTRPSPMLVPPGMGIDESHSSPSVESDWSVHTNEKGTPYYHNRVTKQTSWIKPDVLKTPLERSTSGQPQQGQWKEFMSDDGKPYYYNTLTKKTQWVKPDGEEITKGEQKPAAKAATVDT-VALAAAVQQKKAESDLDKAMKATLASMPNVPLPSEKKEEESVNDEV----------ELKKRQSERFRELLRDKYNDGKITTNCNWDQAVKWIQNDPRFRILNKVSEKKQLFNAWKVQRGKEERDEKRLAIKKSKEDLEKFLQEHPKMKESLKYQKASDIFSKEPLWIAVNDEDRKEIFRDCIDFVARRDKEKKEEDRKRDIAAFSHVLQSMEQITYKTTWAQAQRILYENPQFAERKDLHFMDKEDALTVFEDHIKQAEKEHDEEKEQEEKRLRRQQRKVREEYRLLLESLHKRGELTSMSLWTSLFPIISTDTRFELMLFQPGSSPLDLFKFFVEDLKEQYTEDRRLIKEILTEKGCQVIATTEYREFSDWVVSHEKGGKVDHGNMKLCYNSLIEKAESKAKDEEKESLRRKRRLESEFRNLLKEHNVDKDSEWTVIKPKIEKDKAYLAMENDDERETAFNHY 629          

Query:  898 LSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHDIKSSVSWEEVCQKLGNLEDFKFVELESD 1827
            +  ++ Y+KA  + S  P W AV + DR+EI+ D +  + +R+KE+ +  RKR+I  F+ +L  M  +T+KTTW +AQRIL ENP+F E +DL  MDKEDAL  FE+HI+  EK+H+EEKE+E++RL+R QRK RE + + ++ LH++G+LTS+S+W  L+ IIS D RF  ML QPGS+PLDLFKF+V +LK ++++++R++KEIL ++       T    F   +   E+G  +D GN+++ Y SLIE+AES  K   KE L+++++ E  F+ +LK H++     W  +  K+   +D  ++ +E+D
Sbjct:    1 MKESLKYQKASDIFSKEPLWIAVNDEDRKEIFRDCIDFVARRDKEKKEEDRKRDIAAFSHVLQSMEQITYKTTWAQAQRILYENPQFAERKDLHFMDKEDALTVFEDHIKQAEKEHDEEKEQEEKRLRRQQRKVREEYRLLLESLHKRGELTSMSLWTSLFPIISTDTRFELMLFQPGSSPLDLFKFFVEDLKEQYTEDRRLIKEILTEKGCQVIATTEYREFSDWVVSHEKGGKVDHGNMKLCYNSLIEKAESKAKDEEKESLRRKRRLESEFRNLLKEHNVDKDSEWTVIKPKIE--KDKAYLAMEND 308          

Query:  307 LSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL-AYGNNDTSDNEINENNTTDK-------------PKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEE---GWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFV 1161
            +S  PW    +   K+++YN  T+ SVW++PP+    E +     N  S     ENN + K             PK   +  E  K  L    ++  K         +  V+PA    + +    R K  LEE    ++ +L+E NV  ++T+E  +  I  D RY  L    +++  F+ +  ++ + E+ E R R+K+AKE+ +K L+   +L+    Y    S     P + AV   RDR + + D + ++ K+EK+E +  +++    F ++L+    LT K+ W   ++ L +  R++
Sbjct:  124 VSGTPWCVVWTGDDKVFFYNPSTKCSVWERPPDTYGREDVDKLVQNPPSPKAEEENNQSKKESESESESDEDGPPKAKKSRAEKKKEAL---IAAQKKEKERPRQMLQKPVDPAIEAEM-QAAKEREKVPLEERLKQFKEMLEEKNVSTSSTFEKELSKIVFDKRYLSLG-ATERRACFDAFCREKIESEKAERRKRVKEAKEEFQK-LLAECELNGRSSYSSFTSKFGKDPRYKAVERNRDREDAFNDFVGELHKKEKDEKRAKKEKLKAAFVKLLEEQTGLTRKSKWSTTKKTLEDEERYI 420          

Query:  166 QNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDEL 285
               +P  P+ AW E  A DGR YY+N IT+++TWEKP  L
Sbjct:    3 HGQIPQNPDDAWNEFNAPDGRKYYFNSITQENTWEKPKAL 42          

Query:  307 LSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL-AYGNNDTSDNEINENNTTDK-------------PKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEE---GWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFV 1161
            +S  PW    +   K+++YN  T+ SVW++PP+    E +     N  S     ENN + K             PK   +  E  K  L    ++  K         +  V+PA    + +    R K  LEE    ++ +L+E NV  ++T+E  +  I  D RY  L    +++  F+ +  ++ + E+ E R R+K+AKE+ +K L+   +L+    Y    S     P + AV   RDR + + D + ++ K+EK+E +  +++    F ++L+    LT K+ W   ++ L +  R++
Sbjct:  124 VSGTPWCVVWTGDDKVFFYNPSTKCSVWERPPDTYGREDVDKLVQNPPSPKAEEENNQSKKESESESESDEDGPPKAKKSRAEKKKEAL---IAAQKKEKERPRQMLQKPVDPAIEAEM-QAAKEREKVPLEERLKQFKEMLEEKNVSTSSTFEKELSKIVFDKRYLSLG-ATERRACFDAFCREKIESEKAERRKRVKEAKEEFQK-LLAECELNGRSSYSSFTSKFGKDPRYKAVERNRDREDAFNDFVGELHKKEKDEKRAKKEKLKAAFVKLLEEQTGLTRKSKWSTTKKTLEDEERYI 420          

Query:  166 QNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDEL 285
               +P  P+ AW E  A DGR YY+N IT+++TWEKP  L
Sbjct:    3 HGQIPQNPDDAWNEFNAPDGRKYYFNSITQENTWEKPKAL 42          

Query:  307 LSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL-AYGNNDTSDNEINENNTTDK-------------PKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEE---GWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFV 1161
            +S  PW    +   K+++YN  T+ SVW++PP+    E +     N  S     ENN + K             PK   +  E  K  L    ++  K         +  V+PA    + +    R K  LEE    ++ +L+E NV  ++T+E  +  I  D RY  L    +++  F+ +  ++ + E+ E R R+K+AKE+ +K L+   +L+    Y    S     P + AV   RDR + + D + ++ K+EK+E +  +++    F ++L+    LT K+ W   ++ L +  R++
Sbjct:  124 VSGTPWCVVWTGDDKVFFYNPSTKCSVWERPPDTYGREDVDKLVQNPPSPKAEEENNQSKKESESESESDEDGPPKAKKSRAEKKKEAL---IAAQKKEKERPRQMLQKPVDPAIEAEM-QAAKEREKVPLEERLKQFKEMLEEKNVSTSSTFEKELSKIVFDKRYLSLG-ATERRACFDAFCREKIESEKAERRKRVKEAKEEFQK-LLAECELNGRSSYSSFTSKFGKDPRYKAVERNRDREDAFNDFVGELHKKEKDEKRAKKEKLKAAFVKLLEEQTGLTRKSKWSTTKKTLEDEERYI 420          

Query:  166 QNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDEL 285
               +P  P+ AW E  A DGR YY+N IT+++TWEKP  L
Sbjct:    3 HGQIPQNPDDAWNEFNAPDGRKYYFNSITQENTWEKPKAL 42          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNND----------TSDN---------------------------EINENNTTDKPKESS-AIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYL 1854
            WTEH A DGR YYYN  TKQS+WEKP+ L TPAE + ++CPWKE++S+ GK+YY+N  T+++ W+ PPE  + +  A               TS +                           EI+   T    + SS A+D+A+ ATL ++     + N+ KD  SE              VV++ K E  E ++ +L++ NVP NA W+  VK+IS DPRY   K  N++KQ FN YKTQ+ KDEREE+RL+ KKAKEDLE+FLM+  K++S + Y + + + +    WTAVPE DRR+IYED +  + KREKEEA++L+KRN+K+  E+L+ M ++   TTW EAQ +LL+N  F  D  L  MDKEDALI FEEHIR LEK+ +EE+EREK+R+KR QRKNR++F   +D LHE+GKLTS+S+W +LY IIS D RF  ML Q GSTPLDLFKFYV  LK+RF  EK+I++EIL+++ F     TS E F  V+  D+R  +LD GNV++ Y SL+E+AE+IEK+R+KE +++ +K E   K      ++  +  +E   + + +LE F   E E    K +++++
Sbjct:   56 WTEHKAPDGRPYYYNQNTKQSSWEKPEALMTPAELLHNQCPWKEYRSDTGKVYYHNVATKETCWEPPPEYVDMKAKAKAEEAAAAAKAVAAMTSSSLAGMVPPAALASILPAALPVAPRLPTPEIHSPLTPSSNENSSSAMDQAMAATLAAI--EVPQQNAKKDDKSES------------AVVFKDKREAIESFKELLRDRNVPSNANWDQCVKIISKDPRYAAFKNLNERKQTFNAYKTQKIKDEREESRLKAKKAKEDLEQFLMSSDKMNSQMKYFRCEEVFAGTRTWTAVPEPDRRDIYEDCIFNLAKREKEEARLLKKRNMKVLGELLESMTSINHATTWSEAQVMLLDNVAFKNDVTLLGMDKEDALIVFEEHIRTLEKEEDEEREREKKRMKRQQRKNRDSFLALLDSLHEEGKLTSMSLWVELYPIISADLRFSAMLGQSGSTPLDLFKFYVENLKARFHDEKKIIREILKEKAFVVQAKTSFEDFATVVCEDKRSASLDAGNVKLTYNSLLEKAEAIEKERMKEEVRRLRKLENEIKNEWLEANVSVAEPYESAKKLVEHLEAFALYEKEIGVEKIWEDFV 631          

Query:  307 LSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDK-PKESSAIDEAIKATLGSMPSSSDKVNSHK----------------------DSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRV------------------ILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNI-KLFNEILDVMPNLTFKTTWYEAQRILLENPRF 1158
            ++  PW    +   ++++YN  T+ SVW +P +L         N +  D  +NE     K P+E SA  E       +   +  +V + +                      +S S  E  P   + +  K        LE   R                   +L+E +V   +TWE  +  I  DPRY  L    ++KQ+F  Y   R ++ER+E R ++++ +ED  + LM  ++L     + +     +    + A+ + R+R  ++ + ++++ +REKE+ K+L+K  I K F ++L    ++   T WY+ ++    +PR+
Sbjct:  438 IAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPEDLL--------NREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRVRMISKSKRAEDAALEAEQRAAKERALVPLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYL-LLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDF-RSLMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKED-KLLKKEQIRKDFLDMLRERHDIERHTRWYDIKKKFESDPRY 753          

Query:  181 TLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSEC 318
            T P + W E  A+DGR+YYY+ +T+++TW +PD    PA KI+++ 
Sbjct:  111 TGPPEIWVETKAEDGRSYYYHAVTRETTWSRPD---GPAVKIMTQA 153          

Query:  307 LSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDK-PKESSAIDEAIKATLGSMPSSSDKVNSHK----------------------DSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRV------------------ILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNI-KLFNEILDVMPNLTFKTTWYEAQRILLENPRF 1158
            ++  PW    +   ++++YN  T+ SVW +P +L         N +  D  +NE     K P+E SA  E       +   +  +V + +                      +S S  E  P   + +  K        LE   R                   +L+E +V   +TWE  +  I  DPRY  L    ++KQ+F  Y   R ++ER+E R ++++ +ED  + LM  ++L     + +     +    + A+ + R+R  ++ + ++++ +REKE+ K+L+K  I K F ++L    ++   T WY+ ++    +PR+
Sbjct:  438 IAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPEDLL--------NREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRVRMISKSKRAEDAALEAEQRAAKERALVPLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYL-LLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDF-RSLMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKED-KLLKKEQIRKDFLDMLRERHDIERHTRWYDIKKKFESDPRY 753          

Query:  181 TLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSEC 318
            T P + W E  A+DGR+YYY+ +T+++TW +PD    PA KI+++ 
Sbjct:  111 TGPPEIWVETKAEDGRSYYYHAVTRETTWSRPD---GPAVKIMTQA 153          

Query:  196 AWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGN-NDTSD----------NEINENNTTDKP---KESSAIDEAIKATLGSMPS-----SSD-KVNSHKDSSSEDEVNPAHNI-----PIPEKVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
             WTEH + DG+ YYYN  TKQSTWEKPDELK+PAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E +     N T+D             NE++ T  P    E++     I+     +P+     SSD  VNS +++ S  E  P++++     P   K VY+  TKEE ++ ++ +LKE  V  NA+WE A+K+I  DPRY  L K ++KKQ FN YK Q +K+E+EEAR++ K++KE  ++FL NH K++S   Y+KA+ +  D   W+ VPERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T++TTW EAQ+ LL+NP F EDE+LQ+MDKEDALICFEEHIR LEK+ E+EK++   R +R QRKNRE+F  F+DELH+ G+L S+S W ++Y  IS D RF  ML QPGSTPLDLFKFYV +LK+R+  EKRI+K+IL+D+ F  + NT  E F  VI  D+R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK  +  ++   +WE V ++      F+ + LES+R + +K+++  +
Sbjct:  111 VWTEHKSLDGKIYYYNTETKQSTWEKPDELKSPAEQMLSKCPWKEYKSDTGKPYYYNSQTKESRWTKPKELEDLEAMIKAEENGTADVVAPGTTPALTAQNESSVTVAPVAETEATMATGTIEEQPSHVPAQVAEVSSDVAVNSTEETPSV-ETQPSNDVSKEERPELVKKVYKWNTKEEAKQAFKELLKEKGVSSNASWEQAMKLIINDPRYSALPKLSEKKQAFNAYKVQTEKEEKEEARIKYKESKETFQRFLENHEKMTSTTRYKKAEQMFGDQEVWSCVPERDRLEIYEDVLFYLAKKEKEQAKQLRKRNWEALKNILDNMANVTYRTTWSEAQQYLLDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEDEKQKTLLRERRRQRKNRESFQKFLDELHDHGQLHSMSAWMEMYPTISADIRFSNMLGQPGSTPLDLFKFYVEDLKARYHDEKRIIKDILKDKGFLVEINTGFEDFGSVISSDKRATTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKEAAFKSMLKQATPPLEPEATWEGVRERFLKEPAFEDITLESERKRIFKDFMHVL 694          

Query:   55 IILNGIEISMSNNYQFTLPPLT-HSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELK------------------------------------TPAEKILSE------------------CPWKEFKSEQGKIYYYNTVTQQSVWQKPPEL-AEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDK--------VNSHKDSSSEDEVNPAHN---IPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAK 1041
            + L G+ I +        PPL    +P  T    P S+  ++P LPE  W+E    DGR YYYN  T +STWEKP ELK                                     P E+ ++E                   PW    +   +++YYN  T+ S+W +P EL   A+   Y         +++       KE   ID A++  L   PS + K          + KD + E E+  A +   +P+  ++           +R +L E  V   +TW+  +  I  DPRY  L    ++KQ+F+ Y   R ++ER+E + ++ ++K+D  + +M  +KL +   + +  +  S  P + A+ + +DR  ++ + +    K++KE++K
Sbjct:  307 VPLPGMHIPLPG----MGPPLVPMMHPQLTIAASPMSLAGAIP-LPE--WSEFKTADGRIYYYNNRTLESTWEKPFELKERDKDSDKARDIHNNINLDLKLIDMEAKADFGKSKELPREEDMTEEEKATQKGKPVATNPIPGTPWCVVWTGDERVFYYNPTTRLSMWDRPEELVGRADVDRYIQEPPHKRGLDDIKKIGFNKEE--IDTAMEDMLDDEPSKAKKRKKDDVKEPEAAKDVAVEAELKAARDRALVPLEARM---------NQFRDMLLERGVSAFSTWDKELHKIVFDPRYLLLNP-KERKQVFDQYVKTRAEEERKEKKNKLMQSKDDFRR-MMEDAKLHTRTTFSEFAAKHSKDPRFKAIEKMKDREVMFTEFMTAFRKKDKEDSK 683          

Query:  274 PDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQ-MGKREKEEAKVLRK 1053
            P + +  A   +   PW    +   +++++N     SVW+KP +L +   L     D       ++++++        DE   +      S   K++   D   + +   +H + +P ++           +R +L E  V   +TWE  +  +  DPRY  L    Q+KQI++ +   R  +E +E + ++++AKE+ +K L+  SK++S   ++         P +  V +R  +E++    I  + KR+KE    LRK
Sbjct:  341 PKDKRPVASTPIPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPVDLKDRGDLNRIIEDPPHKRKKDDDSSNSSSGDEEDDEEHNSK-----SKRYKLDHSVDCDEDGKNGSSHRMVLPLELRI-------AHFRDMLLERGVSAFSTWEKELHKVVFDPRYLLLNP-EQRKQIYDQFVKARMNEEHKEKKCKLQQAKEEYKK-LLEESKITSKSTFKDFSEKYGKDPRFKQVQKRKDQELFFSQFINTLKKRDKENRIRLRK 587          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKP---DELKTPAEKI-LSECPWKEFKSEQGKIYYYNTVTQQSVWQKP 399
            W  H  Q+GR YYYN  T++ TW+ P   D L    EK  +++  W     E+G++YYY+    +S W+ P
Sbjct:  207 WETHKDQNGRHYYYNRSTQERTWKPPRARDSLPRKEEKHDMTDTEWLRHTDERGRLYYYSADGSRSEWELP 277          

Query:  124 SYPVPTSYLPPTSVQNSLPT--LPEQA--WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINEN-----------NTTDKPKESSA-----IDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPI-PEKVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            + P PT  +   +V+ S P   +P++   WTEH A DGRTYYYN  TKQSTWEKPDELK+ AE +LS+CPWKE+KS+ GK YYYN+ T++S W KP +L E E L     D S  +  ++           +T   P E  A     I E ++A+    P   + +   KD S+ + +     + + PEK  Y   TKEE ++ ++ +LK+  VP NATWE A+KMI  DPRY  L K ++KKQ FN YK QR+K+E+EE RLR K+AKE L++FL  H K++S   YRKA+ +  +   W+ VPERDR+EIY+D L  + K+EKE+AK LRKRN++    ILD M N++F+TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEKD  EEKER + R +R QRKNRE+F VF+DELHE G+L S+S W +LY  IS D RF  ML Q GSTPLDLFKFYV ELK+RF  EK+I+K+I++DRNF+ + NT+ E F  +I  D+R  TLD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  FK MLK     +++   W+EV ++      F  + +ES+R++ +KE++  I
Sbjct:  113 AQPAPT--VAKATVEESSPAQDIPKKKSLWTEHKAPDGRTYYYNSETKQSTWEKPDELKSKAEFLLSQCPWKEYKSDTGKSYYYNSQTKESRWTKPKDLDELEALIKQKEDVSAEQETQSAISSPSTAVSSDTEMTPTEEPAVAQPSIPEPVEASEVEAPQE-ETLQCQKDISNSEPLRIEDGVKVEPEKRSYNWSTKEEAKQFFKELLKDKGVPSNATWEQAMKMIINDPRYSALPKLSEKKQAFNAYKAQREKEEKEETRLRAKEAKEKLQRFLEQHEKMTSTTRYRKAEQMFGEQEVWSVVPERDRKEIYDDVLFFLAKKEKEQAKQLRKRNVQALKNILDNMTNVSFQTTWSEAQQYLMDNPMFAEDEELQNMDKEDALICFEEHIRALEKDEAEEKERTRLRERRQQRKNRESFQVFLDELHETGQLHSMSTWMELYPSISTDSRFANMLGQTGSTPLDLFKFYVEELKARFHDEKKIIKDIIKDRNFSVEVNTTFEDFAHIISFDKRAATLDAGNIKLTFNSLLEKAEARERERGKEEARKIRRKEAAFKSMLKQSVPPLETDSIWDEVRERFVGDPAFDQITVESERIRLFKEFVHAI 714          

Query:  124 SYPVPTSYLPPTSVQNSLPT--LPEQA--WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINEN-----------NTTDKPKESSA-----IDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPI-PEKVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            + P PT  +   +V+ S P   +P++   WTEH A DGRTYYYN  TKQSTWEKPDELK+ AE +LS+CPWKE+KS+ GK YYYN+ T++S W KP +L E E L     D S  +  ++           +T   P E  A     I E ++A+    P   + +   KD S+ + +     + + PEK  Y   TKEE ++ ++ +LK+  VP NATWE A+KMI  DPRY  L K ++KKQ FN YK QR+K+E+EE RLR K+AKE L++FL  H K++S   YRKA+ +  +   W+ VPERDR+EIY+D L  + K+EKE+AK LRKRN++    ILD M N++F+TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEKD  EEKER + R +R QRKNRE+F VF+DELHE G+L S+S W +LY  IS D RF  ML Q GSTPLDLFKFYV ELK+RF  EK+I+K+I++DRNF+ + NT+ E F  +I  D+R  TLD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  FK MLK     +++   W+EV ++      F  + +ES+R++ +KE++  I
Sbjct:  121 AQPAPT--VAKATVEESSPAQDIPKKKSLWTEHKAPDGRTYYYNSETKQSTWEKPDELKSKAEFLLSQCPWKEYKSDTGKSYYYNSQTKESRWTKPKDLDELEALIKQKEDVSAEQETQSAISSPSTAVSSDTEMTPTEEPAVAQPSIPEPVEASEVEAPQE-ETLQCQKDISNSEPLRIEDGVKVEPEKRSYNWSTKEEAKQFFKELLKDKGVPSNATWEQAMKMIINDPRYSALPKLSEKKQAFNAYKAQREKEEKEETRLRAKEAKEKLQRFLEQHEKMTSTTRYRKAEQMFGEQEVWSVVPERDRKEIYDDVLFFLAKKEKEQAKQLRKRNVQALKNILDNMTNVSFQTTWSEAQQYLMDNPMFAEDEELQNMDKEDALICFEEHIRALEKDEAEEKERTRLRERRQQRKNRESFQVFLDELHETGQLHSMSTWMELYPSISTDSRFANMLGQTGSTPLDLFKFYVEELKARFHDEKKIIKDIIKDRNFSVEVNTTFEDFAHIISFDKRAATLDAGNIKLTFNSLLEKAEARERERGKEEARKIRRKEAAFKSMLKQSVPPLETDSIWDEVRERFVGDPAFDQITVESERIRLFKEFVHAI 722          

Query:  106 LPPLTHSYPVPTSYLPPTSVQNSLPTLPE--------QAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAE-----------KLAYGNNDTSDNEINENNTTDKPKESS-AIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPI-PEKVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            +PPL     +PT  LP  +  ++  ++ +          WTEH A DGRTYYYN  TKQSTWEKPDELK+ AE +LS+CPWKE+KS+ GK YYYN+ T++S W KP +L E E           + A  +  T+ +   E   T++P  +  +I E ++A+    P   + +   KD S+ + +     + + PEK  Y   TKEE ++ ++ +LK+  VP NATWE A+KMI  DPRY  L K ++KKQ FN YK QR+K+E+EE RLR K+AKE L++FL  H K++S   YRKA+ +  +   W+ VPERDR+EIY+D L  + K+EKE+AK LRKRN++    ILD M N++F+TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEKD  EEKER + R +R QRKNRE+F VF+DELHE G+L S+S W +LY  IS D RF  ML Q GSTPLDLFKFYV ELK+RF  EK+I+K+I++DRNF+ + NT+ E F  +I  D+R  TLD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  FK MLK     +++   W+EV ++      F  + +ES+R++ +KE++  I
Sbjct:   63 VPPL-----MPTMMLPAVTSSSTTVSICDITSYSCFKSLWTEHKAPDGRTYYYNSETKQSTWEKPDELKSKAEFLLSQCPWKEYKSDTGKSYYYNSQTKESRWTKPKDLDELEGKGARLEEEKTQSAISSPSTAVSSDTEMTPTEEPAVAQPSIPEPVEASEVEAPQE-ETLQCQKDISNSEPLRIEDGVKVEPEKRSYNWSTKEEAKQFFKELLKDKGVPSNATWEQAMKMIINDPRYSALPKLSEKKQAFNAYKAQREKEEKEETRLRAKEAKEKLQRFLEQHEKMTSTTRYRKAEQMFGEQEVWSVVPERDRKEIYDDVLFFLAKKEKEQAKQLRKRNVQALKNILDNMTNVSFQTTWSEAQQYLMDNPMFAEDEELQNMDKEDALICFEEHIRALEKDEAEEKERTRLRERRQQRKNRESFQVFLDELHETGQLHSMSTWMELYPSISTDSRFANMLGQTGSTPLDLFKFYVEELKARFHDEKKIIKDIIKDRNFSVEVNTTFEDFAHIISFDKRAATLDAGNIKLTFNSLLEKAEARERERGKEEARKIRRKEAAFKSMLKQSVPPLETDSIWDEVRERFVGDPAFDQITVESERIRLFKEFVHAI 667          

Query:  124 SYPVPTSYLPPTSVQNSLPT--LPEQA--WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINEN-----------NTTDKPKESSA-----IDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPI-PEKVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            + P PT  +   +V+ S P   +P++   WTEH A DGRTYYYN  TKQSTWEKPDELK+ AE +LS+CPWKE+KS+ GK YYYN+ T++S W KP +L E E L     D S  +  ++           +T   P E  A     I E ++A+    P   + +   KD S+ + +     + + PEK  Y   TKEE ++ ++ +LK+  VP NATWE A+KMI  DPRY  L K ++KKQ FN YK QR+K+E+EE RLR K+AKE L++FL  H K++S   YRKA+ +  +   W+ VPERDR+EIY+D L  + K+EKE+AK LRKRN++    ILD M N++F+TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEKD  EEKER + R +R QRKNRE+F VF+DELHE G+L S+S W +LY  IS D RF  ML Q GSTPLDLFKFYV ELK+RF  EK+I+K+I++DRNF+ + NT+ E F  +I  D+R  TLD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  FK MLK     +++   W+EV ++      F  + +ES+R++ +KE++  I
Sbjct:  161 AQPAPT--VAKATVEESSPAQDIPKKKSLWTEHKAPDGRTYYYNSETKQSTWEKPDELKSKAEFLLSQCPWKEYKSDTGKSYYYNSQTKESRWTKPKDLDELEALIKQKEDVSAEQETQSAISSPSTAVSSDTEMTPTEEPAVAQPSIPEPVEASEVEAPQE-ETLQCQKDISNSEPLRIEDGVKVEPEKRSYNWSTKEEAKQFFKELLKDKGVPSNATWEQAMKMIINDPRYSALPKLSEKKQAFNAYKAQREKEEKEETRLRAKEAKEKLQRFLEQHEKMTSTTRYRKAEQMFGEQEVWSVVPERDRKEIYDDVLFFLAKKEKEQAKQLRKRNVQALKNILDNMTNVSFQTTWSEAQQYLMDNPMFAEDEELQNMDKEDALICFEEHIRALEKDEAEEKERTRLRERRQQRKNRESFQVFLDELHETGQLHSMSTWMELYPSISTDSRFANMLGQTGSTPLDLFKFYVEELKARFHDEKKIIKDIIKDRNFSVEVNTTFEDFAHIISFDKRAATLDAGNIKLTFNSLLEKAEARERERGKEEARKIRRKEAAFKSMLKQSVPPLETDSIWDEVRERFVGDPAFDQITVESERIRLFKEFVHAI 762          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPEL---------AEAEKLAYGNNDTSDNEINENNTTDKPKESS-AIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPI---------PEKVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            WTEH A DGRTYYYN  TKQSTWEKPDELK+ AE +LS+CPWKE+KS+ GK YYYN+ T++S W KP +L          E EK A  +  T+ +   E   T++P  +  +I E ++A+    P   + +   KD S  +  +PA   P+         PEK  Y   TKEE ++ ++ +LK+  VP NATWE A+KMI  DPRY  L K ++KKQ FN YK QR+K+E+EE RLR K+AKE L++FL  H K++S   YRKA+ +  +   W+ VPERDR+EIY+D L  + K+EKE+AK LRKRN++    ILD M N++F+TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEKD  EEKER + R +R QRKNRE+F VF+DELHE G+L S+S W +LY  IS D RF  ML Q GSTPLDLFKFYV ELK+RF  EK+I+K+I++DRNF+ + NT+ E F  +I  D+R  TLD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  FK MLK     +++   W+EV ++      F  + +ES+R++ +KE++  I
Sbjct:   80 WTEHKAPDGRTYYYNSETKQSTWEKPDELKSKAEFLLSQCPWKEYKSDTGKSYYYNSQTKESRWTKPKDLDELEGKGARLEEEKSAISSPSTAVSSDTEMTPTEEPAVAQPSIPEPVEASEVEAPQE-ETLQCQKDIS--NRYHPATFEPLRIEDGVKVEPEKRSYNWSTKEEAKQFFKELLKDKGVPSNATWEQAMKMIINDPRYSALPKLSEKKQAFNAYKAQREKEEKEETRLRAKEAKEKLQRFLEQHEKMTSTTRYRKAEQMFGEQEVWSVVPERDRKEIYDDVLFFLAKKEKEQAKQLRKRNVQALKNILDNMTNVSFQTTWSEAQQYLMDNPMFAEDEELQNMDKEDALICFEEHIRALEKDEAEEKERTRLRERRQQRKNRESFQVFLDELHETGQLHSMSTWMELYPSISTDSRFANMLGQTGSTPLDLFKFYVEELKARFHDEKKIIKDIIKDRNFSVEVNTTFEDFAHIISFDKRAATLDAGNIKLTFNSLLEKAEARERERGKEEARKIRRKEAAFKSMLKQSVPPLETDSIWDEVRERFVGDPAFDQITVESERIRLFKEFVHAI 654          

Query:  517 IKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD--IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYL 1854
            I +  G  P+  + V+       E+E  PA          + TKEE ++ ++ +LKE  VP NA+WE A+KMI  DPRY  L K ++KKQ FN YK Q +K+E+EEAR + K+AKE  ++FL NH K++S   Y+KA+ +  +   W A+ ERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T+ TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F +F+DELHE G+L S+S W +LY  IS D RF  ML QPGST LDLFKFYV +LK+R+  EK+I+K+IL+D+ F  + NT+ E F+ +I   +R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK     I+    WE++ ++      F+ + LES+R + +K+++
Sbjct:  309 ISSNTGEEPAKQETVSDFTPKKEEEESQPAKKT-----YTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFM 751          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENN--TTDKPKESSAIDEAIKATLGSMPSS----------------------SDKVNSHKDSSSEDEVNPAHNIPI---PEKV-VYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEAR----LRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLE 1146
            WTEH + DGRTYYYN  TKQSTWEKPD+LKTPAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E   Y N   +   I ++N     K +ESS  +E   A+   +P++                      +    +   ++S    N   ++P+   PE   +  T  + E    V  +E     N    TA++ +SGD       +   K++  + +  +++++E + A+       K+  +   K L+   ++ S   + +A  ++ + P ++A+ +  ++++ +    +Q  K EKEEA+   K   + F   L+    +T  T + +A+++  E
Sbjct:  104 WTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE--GYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTASTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAANANTSTTPTNTVGSVPVAPEPEVTSIVATAVDNENTVTVSTEEQAQLANT---TAIQDLSGDIS-SNTGEEPAKQETVSDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGE 446          

Query:  517 IKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYL 1854
            I +  G  P+  + V+       E+E  PA          + TKEE ++ ++ +LKE  VP NA+WE A+KMI  DPRY  L K ++KKQ FN YK Q +K+E+EEAR + K+AKE  ++FL NH K++S   Y+KA+ +  +   W A+ ERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T+ TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F +F+DELHE G+L S+S W +LY  IS D RF  ML QPGST LDLFKFYV +LK+R+  EK+I+K+IL+D+ F  + NT+ E F+ +I   +R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK  +  I+    WE++ ++      F+ + LES+R + +K+++
Sbjct:  324 ISSNTGEEPAKQETVSDFTPKKEEEESQPAKKT-----YTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFM 766          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENN--TTDKPKESSAIDEAIKATLGSMPSS----------------------SDKVNSHKDSSSEDEVNPAHNIPI---PEKV-VYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEAR----LRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLE 1146
            WTEH + DGRTYYYN  TKQSTWEKPD+LKTPAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E   Y N   +   I ++N     K +ESS  +E   A+   +P++                      +    +   ++S    N   ++P+   PE   +  T  + E    V  +E     N    TA++ +SGD       +   K++  + +  +++++E + A+       K+  +   K L+   ++ S   + +A  ++ + P ++A+ +  ++++ +    +Q  K EKEEA+   K   + F   L+    +T  T + +A+++  E
Sbjct:  119 WTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE--GYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTASTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAANANTSTTPTNTVGSVPVAPEPEVTSIVATAVDNENTVTVSTEEQAQLANT---TAIQDLSGDIS-SNTGEEPAKQETVSDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGE 461          

Query:  517 IKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            I +  G  P+  + V+       E+E  PA          + TKEE ++ ++ +LKE  VP NA+WE A+KMI  DPRY  L K ++KKQ FN YK Q +K+E+EEAR + K+AKE  ++FL NH K++S   Y+KA+ +  +   W A+ ERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T+ TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F +F+DELHE G+L S+S W +LY  IS D RF  ML QPGST LDLFKFYV +LK+R+  EK+I+K+IL+D+ F  + NT+ E F+ +I   +R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK  +  I+    WE++ ++      F+ + LES+R + +K+++  +
Sbjct:  351 ISSNTGEEPAKQETVSDFTPKKEEEESQPAKKT-----YTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVL 796          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENN--TTDKPKESSAIDEAIKATLGSMPSS----------------------SDKVNSHKDSSSEDEVNPAHNIPI---PEKV-VYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEAR----LRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLE 1146
            WTEH + DGRTYYYN  TKQSTWEKPD+LKTPAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E   Y N   +   I ++N     K +ESS  +E   A+   +P++                      +    +   ++S    N   ++P+   PE   +  T  + E    V  +E     N    TA++ +SGD       +   K++  + +  +++++E + A+       K+  +   K L+   ++ S   + +A  ++ + P ++A+ +  ++++ +    +Q  K EKEEA+   K   + F   L+    +T  T + +A+++  E
Sbjct:  146 WTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE--GYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTASTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAANANTSTTPTNTVGSVPVAPEPEVTSIVATAVDNENTVTVSTEEQAQLANT---TAIQDLSGDIS-SNTGEEPAKQETVSDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGE 488          

Query:  631 VVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYL---------LTIRSRSRSKFSQEIKRKRKHRSNSKES 1938
            + +  +E+ ++ ++ +L++  VP NA+WE A+KM+  DPRY  L K ++KKQ FN YK QR+K+E+EEARLR K+AK+ L+ FL  H +++S   YR+A+    D   W  VPER+R+E+Y+D L  + K+EKE+AK LR+RNI+    ILD M ++ F+TTW +AQ+ L++NP F +D+ LQ+MDKEDALICFEEHIR LE++ EEE+ER + R +R QRKNREAF  F+DELHE G+L S+S W +LY  +S D RF  ML QPGSTPLDLFKFYV ELK+RF  EK+I+K+IL+DR F  + NT+ E F  VI  D+R   LD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  F+ ML+     ++   +WEEV ++      F+ + LES+R++ ++E+L         L  + R   +  ++  RKR H  +  ES
Sbjct:  271 LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGDLEVWAVVPERERKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDQQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQSFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLETECQHLHTKGRKHGRKGKKHHRKRSHSPSGSES 717          

Query:  112 PLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL 426
            P+T +   P +    ++V  + P  P   W+EH+A DGR YYYN   KQS WEKP  LK+ AE +LS+CPWKE+KS+ GK YYYN  +Q+S W +P +L + E L
Sbjct:   72 PVT-AATAPGADTASSAVAGTGP--PRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSQESRWTRPKDLDDLEAL 173          

Query:  631 VVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYL----------LTIRSRSRSKFSQEIKRKRKHRSNSKES 1938
            + +  +E+ ++ ++ +L++  VP NA+WE A+KM+  DPRY  L K ++KKQ FN YK QR+K+E+EEARLR K+AK+ L+ FL  H +++S   YR+A+    D   W  VPER+R+E+Y+D L  + K+EKE+AK LR+RNI+    ILD M ++ F+TTW +AQ+ L++NP F +D+ LQ+MDKEDALICFEEHIR LE++ EEE+ER + R +R QRKNREAF  F+DELHE G+L S+S W +LY  +S D RF  ML QPGSTPLDLFKFYV ELK+RF  EK+I+K+IL+DR F  + NT+ E F  VI  D+R   LD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  F+ ML+     ++   +WEEV ++      F+ + LES+R++ ++E+L          L  + R   +  ++  RKR H  +  ES
Sbjct:  271 LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGDLEVWAVVPERERKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDQQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQSFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHRKRSHSPSGSES 718          

Query:  112 PLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL 426
            P+T +   P +    ++V  + P  P   W+EH+A DGR YYYN   KQS WEKP  LK+ AE +LS+CPWKE+KS+ GK YYYN  +Q+S W +P +L + E L
Sbjct:   72 PVT-AATAPGADTASSAVAGTGP--PRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSQESRWTRPKDLDDLEAL 173          

Query:   91 NYQFTLPPLTHSYPVPTSYLPPTSV---QNSLPTLP--------------------EQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECP----WKEFKSEQGKIYYYNTVTQQSVWQKPP--ELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEY 1851
            N +F +PP+     VP   +P  SV     + PT P                    E  W+ H  + G  YY+N +TKQ++W KPD LKTP E+  S  P    WKEF S+ GK YYYNT+T+++ W KP   E+ + E+       T D  +       + K  S +D+A+KATL SMP+        ++ S  DEV          ++  R  E   E  R    +  +  N  W+ AVK I  DPR++ L K ++KKQ+FN +K QR K+ER+E RL IKK+KEDLEKFL  H K+  ++ Y+KA  + S  P W AV + DR+EI+ D +  + +R+KE+ +  RKR+I  F+ +L  M  +T+KTTW +AQRIL ENP+F E +DL  MDKEDAL  FE+HI+  EK+H+EEKE+E++RL+R QRK RE + + ++ LH++G+LTS+S+W  L+ IIS D RF  ML QPGS+PLDLFKF+V +LK ++++++R++KEIL ++       T    F   +   E+G  +D GN+++ Y SLIE+AES  K   KE L+++++ E  F+ +LK H++     W  +  K+   + +  +E + +R   +  Y
Sbjct:   25 NQRFGMPPVGSIAQVPLLQMPTHSVVAPHVAAPTRPSPMLVPPGMGIDESHSSPSVESDWSVHTNEKGTPYYHNRVTKQTSWIKPDVLKTPLERSTSGQPQQGQWKEFMSDDGKPYYYNTLTKKTQWVKPDGEEITKGEQKPAAKAATVDT-VALAAAVQQKKAESDLDKAMKATLASMPNVPLPSEKKEEESVNDEV----------ELKKRQSERFRELLRDKYNDGKITTNCNWDQAVKWIQNDPRFRILNKVSEKKQLFNAWKVQRGKEERDEKRLAIKKSKEDLEKFLQEHPKMKESLKYQKASDIFSKEPLWIAVNDEDRKEIFRDCIDFVARRDKEKKEEDRKRDIAAFSHVLQSMEQITYKTTWAQAQRILYENPQFAERKDLHFMDKEDALTVFEDHIKQAEKEHDEEKEQEEKRLRRQQRKVREEYRLLLESLHKRGELTSMSLWTSLFPIISTDTRFELMLFQPGSSPLDLFKFFVEDLKEQYTEDRRLIKEILTEKGCQVIATTEYREFSDWVVSHEKGGKVDHGNMKLCYNSLIEKAESKAKDEEKESLRRKRRLESEFRNLLKEHNVDKDSEWTVIKPKIEKDKAYLAMENDDERETAFNHY 629          

Query:  517 IKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            I +  G  P+  + V+       E+E  PA          + TKEE ++ ++ +LKE  VP NA+WE A+KMI  DPRY  L K ++KKQ FN YK Q +K+E+EEAR + K+AKE  ++FL NH K++S   Y+KA+ +  +   W A+ ERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T+ TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F +F+DELHE G+L S+S W +LY  IS D RF  ML QPGST LDLFKFYV +LK+R+  EK+I+K+IL+D+ F  + NT+ E F+ +I   +R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK  +  I+    WE++ ++      F+ + LES+R + +K+++  +
Sbjct:  351 ISSNTGEEPAKQETVSDFTPKKEEEESQPAKKT-----YTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVL 796          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENN--TTDKPKESSAIDEAIKATLGSMPSS----------------------SDKVNSHKDSSSEDEVNPAHNIPI---PEKV-VYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEAR----LRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLE 1146
            WTEH + DGRTYYYN  TKQSTWEKPD+LKTPAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E   Y N   +   I ++N     K +ESS  +E   A+   +P++                      +    +   ++S    N   ++P+   PE   +  T  + E    V  +E     N    TA++ +SGD       +   K++  + +  +++++E + A+       K+  +   K L+   ++ S   + +A  ++ + P ++A+ +  ++++ +    +Q  K EKEEA+   K   + F   L+    +T  T + +A+++  E
Sbjct:  146 WTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE--GYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTASTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAANANTSTTPTNTVGSVPVAPEPEVTSIVATAVDNENTVTVSTEEQAQLANT---TAIQDLSGDIS-SNTGEEPAKQETVSDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGE 488          

Query:  631 VVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYL----------LTIRSRSRSKFSQEIKRKRKHRSNSKES 1938
            + +  +E+ ++ ++ +L++  VP NA+WE A+KM+  DPRY  L K ++KKQ FN YK QR+K+E+EEARLR K+AK+ L+ FL  H +++S   YR+A+    D   W  VPER+R+E+Y+D L  + K+EKE+AK LR+RNI+    ILD M ++ F+TTW +AQ+ L++NP F +D+ LQ+MDKEDALICFEEHIR LE++ EEE+ER + R +R QRKNREAF  F+DELHE G+L S+S W +LY  +S D RF  ML QPGSTPLDLFKFYV ELK+RF  EK+I+K+IL+DR F  + NT+ E F  VI  D+R   LD GN+++ + SL+E+AE+ E +R KE  ++ ++ E  F+ ML+     ++   +WEEV ++      F+ + LES+R++ ++E+L          L  + R   +  ++  RKR H  +  ES
Sbjct:  271 LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGDLEVWAVVPERERKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDQQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQSFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARETEREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHRKRSHSPSGSES 718          

Query:  112 PLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL 426
            P+T +   P +    ++V  + P  P   W+EH+A DGR YYYN   KQS WEKP  LK+ AE +LS+CPWKE+KS+ GK YYYN  +Q+S W +P +L + E L
Sbjct:   72 PVT-AATAPGADTASSAVAGTGP--PRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSQESRWTRPKDLDDLEAL 173          

Query:  616 PIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            P  +   + TKEE ++ ++ +LKE  VP NA+WE A+KMI  DPRY  L K ++KKQ FN YK Q +K+E+EEAR + K+AKE  ++FL NH K++S   Y+KA+ +  +   W A+ ERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T+ TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F +F+DELHE G+L S+S W +LY  IS D RF  ML QPGST LDLFKFYV +LK+R+  EK+I+K+IL+D+ F  + NT+ E F+ +I   +R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK  +  I+    WE++ ++      F+ + LES+R + +K+++  +
Sbjct:  383 PAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVL 800          

Query:   58 ILNGIEIS-MSN-NYQFTLPPLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENN--TTDKPKESSAIDEAIKATLGSMPSS 549
            ++ G+ +S MS  + Q  LPP  +S  V        S   S+       WTEH + DGRTYYYN  TKQSTWEKPD+LKTPAE++LS+CPWKE+KS+ GK YYYN+ T++S W KP EL + E   Y N   + + I ++N     K +ESS  +E    +   +P++
Sbjct:  107 VMPGMMMSHMSQASMQPALPPGVNSMDVAAGT---ASGAKSM-------WTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE--GYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTT 262          

Query:  631 VVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSH--DIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSSREH 1956
            + +  +E+ ++ ++ +L++  VP NA+WE A+KM+  DPRY  L K ++KKQ FN YK QR+K+E+EEARLR K+AK+ L+ FL  H +++S   YR+A+    +   W  VPERDR+E+Y+D L  + K+EKE+AK LR+RNI+    ILD M ++ F+TTW +AQ+ L++NP F +D  LQ+MDKEDALICFEEHIR LE++ EEE+ER + R +R QRKNREAF  F+DELHE G+L S+S W +LY  +S D RF  ML QPGSTPLDLFKFYV ELK+RF  EK+I+K+IL+DR F  + NT+ E F  VI  D+R   LD GN+++ + SL+E+AE+ E++R KE  ++ ++ E  F+ ML+     ++   +WEEV ++      F+ + LES+R++ ++E+L  +    +++      + RKH    K+    R H
Sbjct:  271 LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVL---EQTECQHLHTKGRKHGRKGKKHHHKRSH 711          

Query:  112 PLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKL 426
            P+T +   P +    ++V  + P  P   W+EH+A DGR YYYN   KQS WEKP  LK+ AE +LS+CPWKE+KS+ GK YYYN  +++S W +P +L + E L
Sbjct:   72 PVT-AATAPGADTASSAVAGTGP--PRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVL 173          

Query:  109 PPLTHSYPVPTSYL-PPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNE----------------INENNTTDKPKESSAIDEAIKATLGS------------MPSSSDKV-NSHKDSSSEDEVNPAHNIP--------IPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD-IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVS 1944
            P   H+  VPTS   P TSV           W EH + DGR YYYN  T+Q+TWEKP ELKT  EKIL  CPWKEFKSE GK YY+N  T+QSVW KP EL EAE  A     T +                      +   KP E S I+ A+KATL S            +P   +KV +S KD S +++  P  N+         +PE   Y+T+ E+ EG R + ++ NVPG ATWE A+K+ISGDPRY  L+ +N+KKQIFN YKTQR K+EREE R+RIK+AKEDLEK+L+  +KL S + YR+ D LLSD  EWT VP+RDRREI++D + ++GKRE+EEAK+LRKRNI++FNEIL  M +LT++TTW EAQ++LL+N RF  D DLQ++DKEDAL+CFEEHI +LE++H+E+KERE+RR KR QRKNREAF V +DELHE+  LTS+S+WKDLY II++D+RF+KML+Q GSTPLDLFKFYV  LK+RF  EK+I+KEIL+  + + D + S E F  +I  DER + +D GN+RM Y SL+E+A+  E++R ++  ++ +K E +F +ML +   I+S+ SWEEV +KL +   FK + LES+R++ +KEY+++I +       +   RK KHR     SV+
Sbjct:   16 PGYAHATFVPTSIPNPVTSVTQLSAAQVNAGWVEHHSHDGRKYYYNTFTQQTTWEKPQELKTQREKILCNCPWKEFKSENGKPYYFNENTKQSVWVKPQELIEAENQAAACTPTLNTAVPEPPPIIPPVTPCTPATPKDDISKPPEPSEIERAMKATLASFETSDTGPSSMSIPLPPEKVYDSDKDESEDEKPTPNVNVTTFSPNTQTVPE---YKTRGEMAEGLRRLFRDCNVPGGATWEQALKLISGDPRYSILRTFNEKKQIFNVYKTQRLKEEREEQRIRIKRAKEDLEKYLLKCNKLHSTMSYRRVDQLLSDTKEWTDVPDRDRREIFDDVMQEVGKREREEAKILRKRNIRVFNEILGEMLDLTYRTTWSEAQQMLLDNTRFTGDVDLQNLDKEDALVCFEEHICMLEQEHDEDKERERRRQKREQRKNREAFIVLLDELHEQKLLTSMSLWKDLYHIINKDDRFHKMLAQRGSTPLDLFKFYVEALKARFPAEKKIIKEILKYSSTSIDLSVSYEDFCSIISADERSKGIDSGNMRMTYDSLLEKAQGRERERQRDDARRMRKLEQHFCEMLATSSFIQSNTSWEEVREKLSDHPAFKGMSLESERIRLFKEYIMSIDNSLNEDAHR--SRKDKHRRERSPSVN 661          

Query:  109 PPLTHSYPVPTSYLP----PTSVQNSLPTLPEQA-WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYG---------------NNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNS--------------------HKDSSSEDEVNPAHNIPIPEKVV---YRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD-IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSS 1947
            P  T ++  P  Y P    P  VQ ++P       W EH + DGR YYYN +T+Q+TWEKP ELK+  E ILS CPWKEFKSE GK YY+N  T+QSVW KP EL EAE+ A                   +T            KP E SAI++A+ ATL S   SS K +S                     K  S +   N +     P  +V   Y+T+ E+ EG R + ++ NVPG +TWE AVK+IS DPRY  LK + +KKQIFN YKTQR K+EREE RLR K+AKEDLE+FL+ H K+ S + YR+ D LLSD  EW  VP++DRRE+++D + ++ KRE+EEAKVLRKRNIK+FNEIL  MP LT++TTW EAQ++LL+N RF  D +LQS+DKEDAL+CFEEHI +LE++H+EEKERE+R+ KR+QRKNREAF V +DELHE+  L+S SMWKDLY IISRDERF+KML+Q GSTPLDLFKFYV  LK+R+  EK+++KEIL+D  F  D +TS E F  VI  DER + +D GN+RM + SL+E+A+  E++R ++  ++ +K E NF  ML S + I+   SW+EV +K  +   F+ + LES+R++ +K+Y++++ S +++  S++ +R RK +   ++S S+
Sbjct:    5 PAFTGAHTFPHPYAPMAYLPAGVQAAIPVAATAGSWAEHTSHDGRKYYYNTLTQQTTWEKPPELKSTRELILSSCPWKEFKSENGKPYYFNEQTRQSVWVKPQELMEAEQQAEALAPMPSPAQEKHTPLQLNTPCTPATPKEEFGKPPEPSAIEKAMLATLASYDISSSKTDSIPIPPPPPNEMPTEAKSEQLEKTDSEDKSSNVSRRTGSPAPLVMHEYKTRGEMAEGLRRLFRDCNVPGGSTWEQAVKLISADPRYNLLKSFTEKKQIFNVYKTQRLKEEREEQRLRAKQAKEDLERFLLRHPKVHSTMSYRRVDQLLSDAQEWKVVPDKDRRELFDDVMQEISKREREEAKVLRKRNIKVFNEILSDMPKLTYRTTWSEAQQMLLDNSRFTGDVELQSLDKEDALVCFEEHICMLEQEHDEEKERERRKQKRIQRKNREAFIVLLDELHEQKLLSSTSMWKDLYSIISRDERFHKMLAQRGSTPLDLFKFYVEALKTRYPAEKKLIKEILKDIGFNVDLSTSFEDFCTVIGRDERSKGVDDGNLRMTFDSLLEKAKGRERERQRDDARRLRKLEQNFCGMLSSANFIRPDTSWDEVREKFNDHPAFRALSLESERIRVFKDYIISMDSAAQAD-SEKSRRNRKDKRRQEDSESA 660          

Query:  109 PPLTHSYPVPTSYLP----PTSVQNSLPTLPEQA-WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYG---------------NNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNS--------------------HKDSSSEDEVNPAHNIPIPEKVV---YRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD-IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKES 1938
            P  T ++  P  Y P    P  VQ ++P       W EH + DGR YYYN +T+Q+TWEKP ELK+  E ILS CPWKEFKSE GK YY+N  T+QSVW KP EL EAE+ A                   +T            KP E SAI++A+ ATL S   SS K +S                     K  S +   N +     P  +V   Y+T+ E+ EG R + ++ NVPG +TWE AVK+IS DPRY  LK + +KKQIFN YKTQR K+EREE RLR K+AKEDLE+FL+ H K+ S + YR+ D LLSD  EW  VP++DRRE+++D + ++ KRE+EEAKVLRKRNIK+FNEIL  MP LT++TTW EAQ++LL+N RF  D +LQS+DKEDAL+CFEEHI +LE++H+EEKERE+R+ KR+QRKNREAF V +DELHE+  L+S SMWKDLY IISRD+RF+KML+Q GSTPLDLFKFYV  LK+R+  EK+++KEIL+D  F  D +TS E F  VI  DER + +D GN+RM + SL+E+A+  E++R ++  ++ +K E NF  ML S + I+   SW+EV ++  +   F+ + LES+R++ +K+Y++++ S +++  S++ +R RK +   ++S
Sbjct:    5 PAFTGAHTFPHPYAPMAYLPAGVQAAIPVAATAGGWAEHTSHDGRKYYYNTLTQQTTWEKPPELKSTRELILSSCPWKEFKSENGKPYYFNEQTRQSVWVKPQELMEAEQQAEALAPMPSPAQEKHTPLQLNTPCTPATPKEEFGKPPEPSAIEKAMLATLASYDISSSKTDSIPIPPPPPNEMSTEAKSEQLEKTDSEDKSSNVSRRTGSPAPLVMHEYKTRGEMAEGLRRLFRDCNVPGGSTWEQAVKLISADPRYNLLKSFTEKKQIFNVYKTQRLKEEREEQRLRAKQAKEDLERFLLRHPKVHSTMSYRRVDQLLSDAQEWKVVPDKDRRELFDDVMQEISKREREEAKVLRKRNIKVFNEILSDMPKLTYRTTWSEAQQMLLDNSRFTGDVELQSLDKEDALVCFEEHICMLEQEHDEEKERERRKQKRIQRKNREAFIVLLDELHEQKLLSSTSMWKDLYSIISRDDRFHKMLAQRGSTPLDLFKFYVEALKTRYPAEKKLIKEILKDIGFNVDLSTSFEDFCTVIGRDERSKGVDDGNLRMTFDSLLEKAKGRERERQRDDARRLRKLEQNFCGMLSSANFIRPDTSWDEVRERFNDHPAFRALSLESERIRVFKDYIISMDSAAQAD-SEKSRRNRKDKRRQEDS 657          

Query:  109 PPLTHSYPVP---TSYLPPTSVQNSLPTL-PEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDT--SDNEINENNTTD-------------KPKESSAIDEAIKATLGS--MPSSSD---------------KVNSHKDSSSEDEVNPAHNI------PIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD-IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRS---KFSQEIKRKRKHRSNSKESVSSRE 1953
            PP T ++  P    +YLP      ++PT+ P   W EH + DGR YYYN  T+Q+TW+KP ELKT  E ILS CPWKEFKSE G++YY+N  T+QSVW KP EL +AE  A   + T  SD ++  ++                KP E SAI++A+ ATL S  +P+++D                 N + D +S D    A         P P +  Y+T+ E+ EG R + ++ NVPG+ATWE A+K+IS DPRY  LK + +KKQIFN YKTQR K+EREE RLR K+AKEDLE+FL+ H KL S + YRK + LLSD  EWT+VP+RDRRE++ED +  + KRE++EAKV+RKRNIK+F+EIL  MPNLTF+TTW EAQ++LL+NP+F  D +LQS+DKEDALICFEEHI +LE++H+EEKER++RR KR QRKNREAF V +DELHE   LT+ S+WKDLY II+RDERF+KML+Q GSTPLDLFKFYV  LK+R+  E++++KEI++D     D +TS E F+ ++  DER + +D GN+RM Y S +E+A+  E++R ++  ++ +K E NF +ML S   I  + +WEEV         F  + LES+R++ +KEYL+++ S + +   K  +  K K +H+    ESV  RE
Sbjct:    5 PPYTATFHHPYAQVAYLPA-----AVPTIAPVSQWIEHTSHDGRKYYYNTATQQTTWDKPQELKTTRELILSSCPWKEFKSENGRLYYFNEQTKQSVWVKPQELIDAENQAESASSTAVSDKKVPASSVLGTPCTPATPKDEPSKPPEPSAIEKAMMATLSSYDLPTTTDSIPIPPPPPTEAPAETPNEYVDRTSADNAGRAGTAGSSGGSPAPHQE-YKTRGEMAEGLRRLFRDCNVPGSATWEQALKLISADPRYSLLKTFTEKKQIFNVYKTQRLKEEREEQRLRAKQAKEDLERFLLRHPKLHSTMSYRKVEQLLSDAREWTSVPDRDRRELFEDVMQLISKRERDEAKVVRKRNIKVFHEILSGMPNLTFRTTWSEAQQMLLDNPKFTGDIELQSLDKEDALICFEEHICMLEQEHDEEKERDRRRQKRQQRKNREAFIVLLDELHENKLLTATSLWKDLYSIINRDERFHKMLAQRGSTPLDLFKFYVEALKARYPAERKLIKEIIKDNGLNIDLSTSFEDFVDLVSKDERSKGIDDGNMRMTYESFLEKAQGRERERQRDDARRMRKLEQNFCEMLCSAKFIGHNTTWEEVRDHFSGHPAFCALTLESERIRLFKEYLISLESAALAESEKSRKGHKEKHRHKREVSESVDKRE 659          

Query:  109 PPLTHSYPVP---TSYLPPTSVQNSLPTL-PEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDT--SDNEI------------NENNTTDKPKESSAIDEAIKATLGS--MPSSSDKV---------------NSHKDSSSEDEVN------PAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD-IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRS---KFSQEIKRKRKHRSNSKESVSSRE 1953
            PP T ++  P    +YLP      ++PT+ P   W EH + DGR YYYN  T+Q+TWEKP ELKT  E ILS CPWKEFKSE G++YY+N  T+QSVW KP EL +AE  A   + T  SD ++               +   KP E SAI++A+ ATL S  +P+++D +               N + D ++ D          +   P P +  Y+T+ E+ EG R + ++ NVPG+ATWE A+K+IS DPRY  LK + +KKQIFN YKTQR K+EREE RLR K+AKEDLE+FL+ H KL S + YRK + LLSD  EWT+VP+RDRRE++ED +  + KRE++EAKV+RKRNIK+F+EIL  MPNLTF+TTW EAQ++LL+NP+F  D +LQS+DKEDALICFEEHI +LE++H+EEKER++RR KR QRKNREAF V +DELHE   LT+ S+WKDLY II+RDERF+KML+Q GSTPLDLFKFYV  LK+R+  E++++KEI++D     D +TS E F+ ++  DER + +D GN+RM Y S +E+A+  E++R ++  ++ +K E NF +ML S   I  + +WEEV         F  + LES+R++ +KEYL+++ S + +   K  +  K K +H+    ESV  RE
Sbjct:    5 PPYTATFHHPYAQVAYLPA-----AVPTIAPVSQWIEHTSHDGRKYYYNTATQQTTWEKPQELKTTRELILSSCPWKEFKSENGRLYYFNEQTKQSVWVKPQELIDAESQAESASSTTVSDKKVPTSVLGTPCTPATPKDEPSKPPEPSAIEKAMMATLSSYDLPTTTDSIPIPPPPPAEAPAETQNEYVDRTNADNAGRVGTASSSGGSPAPHQE-YKTRGEMAEGLRRLFRDCNVPGSATWEQALKLISADPRYSLLKTFTEKKQIFNVYKTQRLKEEREEQRLRAKQAKEDLERFLLRHPKLHSTMSYRKVEQLLSDAREWTSVPDRDRRELFEDVMQLISKRERDEAKVVRKRNIKVFHEILSGMPNLTFRTTWSEAQQMLLDNPKFTGDIELQSLDKEDALICFEEHICMLEQEHDEEKERDRRRQKRQQRKNREAFIVLLDELHENKLLTATSLWKDLYSIINRDERFHKMLAQRGSTPLDLFKFYVEALKARYPAERKLIKEIIKDNGLNIDLSTSFEDFVALVSKDERSKGIDDGNMRMTYESFLEKAQGRERERQRDDARRMRKLEQNFCEMLCSAKFIGHNTTWEEVRDHFSGHPAFCALTLESERIRLFKEYLISLESAALAESEKSRKGHKEKHRHKREVSESVDKRE 658          

Query:  322 WKEFKSEQGKIYYYNTVTQQSVWQKPPEL-AEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKA--------------------------------------------TLGSMPSSSDKVNSHKDSSSEDEV----NPAHNIPIPE------KVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD--IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            W E KS  GK YYYNT T+QS W+KP EL + AE++    +     E N+ +   KPKE   ++  IKA                                             L  MP    +V+S    +S ++      PA N    E      K VY+  TKEE ++ ++ +LKE  V  NA+WE A+K+I  DPRY  L K ++KKQ FN YK Q +K+E+EEAR++ K++KE  ++FL NH K++S   Y+KA+ +  D   W+ VPERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T++TTW EAQ+ LL+NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F  F+DELH+ G+L S+S W ++Y  IS D RF  ML QPGSTPLDLFKFYV +LK+R+  EKRI+K+IL+D+ F  + +TS E F  VI  D+R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK     ++   SWE V ++      F+ + LES+R + +K+++  +
Sbjct:   32 WTEHKSLDGKTYYYNTETKQSTWEKPDELKSPAEQML---SKCPWKEYNKESRWTKPKELEDLEAMIKAEENGNTDVVAPGTAPPLAAQTDTAVAMAAGAEADATIATAAAEEQLSQMPMQGAEVSSDATMTSTEDTPVIETPASNDSSKEERPELVKKVYKWNTKEEAKQAFKELLKEKGVSSNASWEQAMKLIINDPRYSALPKLSEKKQAFNAYKVQTEKEEKEEARIKYKESKETFQRFLENHEKMTSTTRYKKAEQMFGDQEVWSCVPERDRLEIYEDVLFYLAKKEKEQAKQLRKRNWEALKNILDNMANVTYRTTWSEAQQYLLDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQKFLDELHDHGQLHSMSAWMEMYPTISADIRFASMLGQPGSTPLDLFKFYVEDLKARYHDEKRIIKDILKDKGFLVEISTSFEDFGSVISSDKRATTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKEAAFKSMLKQATPPLEPEASWEGVRERFLKEAAFEDITLESERKRIFKDFMHVL 601          

Query:  322 WKEFKSEQGKIYYYNTVTQQSVWQKPPEL-AEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKA--------------------------------------------TLGSMPSSSDKVNSHKDSSSEDEV----NPAHNIPIPE------KVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHD--IKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            W E KS  GK YYYNT T+QS W+KP EL + AE++    +     E N+ +   KPKE   ++  IKA                                             L  MP    +V+S    +S ++      PA N    E      K VY+  TKEE ++ ++ +LKE  V  NA+WE A+K+I  DPRY  L K ++KKQ FN YK Q +K+E+EEAR++ K++KE  ++FL NH K++S   Y+KA+ +  D   W+ VPERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T++TTW EAQ+ LL+NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F  F+DELH+ G+L S+S W ++Y  IS D RF  ML QPGSTPLDLFKFYV +LK+R+  EKRI+K+IL+D+ F  + +TS E F  VI  D+R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK     ++   SWE V ++      F+ + LES+R + +K+++  +
Sbjct:   62 WTEHKSLDGKTYYYNTETKQSTWEKPDELKSPAEQML---SKCPWKEYNKESRWTKPKELEDLEAMIKAEENGNTDVVAPGTAPPLAAQTDTAVAMAAGAEADATIATAAAEEQLSQMPMQGAEVSSDATMTSTEDTPVIETPASNDSSKEERPELVKKVYKWNTKEEAKQAFKELLKEKGVSSNASWEQAMKLIINDPRYSALPKLSEKKQAFNAYKVQTEKEEKEEARIKYKESKETFQRFLENHEKMTSTTRYKKAEQMFGDQEVWSCVPERDRLEIYEDVLFYLAKKEKEQAKQLRKRNWEALKNILDNMANVTYRTTWSEAQQYLLDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQKFLDELHDHGQLHSMSAWMEMYPTISADIRFASMLGQPGSTPLDLFKFYVEDLKARYHDEKRIIKDILKDKGFLVEISTSFEDFGSVISSDKRATTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKEAAFKSMLKQATPPLEPEASWEGVRERFLKEAAFEDITLESERKRIFKDFMHVL 631          

Query:  196 AWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAE 420
             WTEH + DG+TYYYN  TKQSTWEKPDELK+PAE++LS+CPWKE+KS+ GK YYYN+ +++S W KP EL + E
Sbjct:   79 VWTEHKSLDGKTYYYNTETKQSTWEKPDELKSPAEQMLSKCPWKEYKSDTGKPYYYNSQSKESRWTKPKELEDLE 153          

Query:  316 CPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSM---PSSSD-------------KVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRF 1158
             PW    +   ++++YN  T+ S+W++P EL        G  D  D  I E      P     +D   K   G +   P++++             KV   KDS SE E      +    +     +E     ++ +L E  V   +TWE  +  I  DPRY  L    ++KQ+F+ Y   R ++ER+E R +I +AK+D  K +M  ++L     + +  +  +    + A+ + +DR  I+ + +  + K+EK+ +K   ++  + F E+L    ++  +  W + +  +  +PR+
Sbjct:  467 TPWCVVWTGDERVFFYNPTTRMSMWERPEELV-------GRADV-DKSIQE------PPHKKGLDNGPKLVFGKLEQEPAATEDTSEDEPSRAKKRKVEERKDSDSEKEAAMEAELRAARERAVVPQETRMSQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNP-KERKQVFDQYVKTRAEEERKEKRNKIMQAKDDFRK-MMEEARLGVRTTFSEFAAKHARDSRFKAIDKMKDREAIFIEFMTSLRKKEKDNSKNRGEKVKQDFFELLSDY-HVDGQQRWSKVKEKMETDPRY 747          

Query:  316 CPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSM---PSSSD-------------KVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRF 1158
             PW    +   ++++YN  T+ S+W++P EL        G  D  D  I E      P     +D   K   G +   P++++             KV   KDS SE E      +    +     +E     ++ +L E  V   +TWE  +  I  DPRY  L    ++KQ+F+ Y   R ++ER+E R +I +AK+D  K +M  ++L     + +  +  +    + A+ + +DR  I+ + +  + K+EK+ +K   ++  + F E+L    ++  +  W + +  +  +PR+
Sbjct:  446 TPWCVVWTGDERVFFYNPTTRMSMWERPEELV-------GRADV-DKSIQE------PPHKKGLDNGPKLVFGKLEQEPAATEDTSEDEPSRAKKRKVEERKDSDSEKEAAMEAELRAARERAVVPQETRMSQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNP-KERKQVFDQYVKTRAEEERKEKRNKIMQAKDDFRK-MMEEARLGVRTTFSEFAAKHARDSRFKAIDKMKDREAIFIEFMTSLRKKEKDNSKNRGEKVKQDFFELLSDY-HVDGQQRWSKVKEKMETDPRY 726          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNND---TSDNEINENNTTDKPKESSAID-EAIKATLGSMPSSSDKVNSHKDSSS---------------EDEV--------------------NPAHNIPI-----------PEKVVY--RTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKS------HDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            WTEH + DGRTY+YN  TKQSTWEKP ELK+P E +++ CPWKE+KS+ GK Y+YN  T++S W KP EL + E +   + D   T ++ +      + P  ++    +A   T GS  +SS   N    S++               +D V                    N    +P             EK VY   TKEE  + ++ +LK+  VP +A+WE A+KMI  DPRY  L K ++KKQ +N YKTQR K+E+EEARLR K+AK+ L++FL  H KL+S + YRKA+ +      W  V ERDR EIYED +  + K+EKEEAK LRKRNI+    ILD M ++TF+TTW EAQ+ L++NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EE+KE+ + R +RMQRKNRE F +F+DELH  GKL S+S W DLY  +S D RF +ML QPGSTPLDLFKFYV +LK+R+ +EK+I+K++L+D+NF  +  T+ E F  +I  D+R  TLD GNV++A+ SLIE+AE+ EK+R KE  ++QK+ E  F+ MLK       HD K    W++V  +  N   F  + +ES+R++ +KEY+  +
Sbjct:  114 WTEHKSPDGRTYFYNSDTKQSTWEKPLELKSPGEMLVASCPWKEYKSDTGKPYFYNAQTKESRWTKPKELEDLENMIKAHEDSGSTGESCLRHRGQMELPVPAAVTTVQAASGTPGSTGTSSPVENGASPSAAGTTSALPPSADGTPQQDGVSLAAGGAVTATASANAVAMGNATATVPPVIVVKEDGRKKKEKKVYTWNTKEEARQAFKDLLKDKKVPASASWEQAMKMIINDPRYSALPKLSEKKQAYNAYKTQRDKEEKEEARLRAKEAKDRLQRFLETHEKLNSYVKYRKAEQMFGSMEVWNNVQERDRNEIYEDVIFFLAKKEKEEAKRLRKRNIQALKSILDSMTSVTFRTTWSEAQQHLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEDKEKGRLRERRMQRKNRELFQLFLDELHNNGKLHSMSTWMDLYPAVSADIRFSRMLGQPGSTPLDLFKFYVEDLKARYHEEKKIIKDVLKDKNFMVEVKTTFEEFASLISSDKRAVTLDAGNVKLAFNSLIEKAEAREKEREKEEARKQKRKEAAFRNMLKQATPPLEHDSK----WDDVRDRFVNDSAFDQITVESERIRLFKEYVGAL 722          

Query:  187 PEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELK 288
            P   WTEH   DGRTYYYN+ T +STWEKP EL+
Sbjct:  314 PSAEWTEHKTADGRTYYYNIRTLESTWEKPAELR 347          

Query:  676 ILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYK---TQRQKDERE---------EARLR-----IKKAKEDLEKFL---MNHSKLSSAIGYRKADSLLSDCPEWTAVPERD-RREIYED------TLIQMGKREK---EEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPR 1155
            +L E ++ G + W  A + + GD R+Q ++   Q+++ F  +    TQ    ERE         EA LR     ++KA+ +  + +       K   AI + KA  LLSD    + V   D RR + +D      +L+   ++EK   E    L KR  + F ++LD    +T  +TW E ++++ E+PR
Sbjct:  302 LLMEQHLDGQSRWTKARERMEGDTRFQAVESSGQREEWFRQHVEKLTQAGDSERERELERQARTEASLREREREVQKARSEQTREIDREREQHKREEAIQHFKA--LLSDMVRSSEVNWDDTRRSLRKDHRWELASLLDRSEKEKLFKEHVDALSKRKKEQFKQLLDETSEITLTSTWREVRKLIKEDPR 489          

Query:  676 ILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYK---TQRQKDERE---------EARLR-----IKKAKEDLEKFL---MNHSKLSSAIGYRKADSLLSDCPEWTAVPERD-RREIYED------TLIQMGKREK---EEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPR 1155
            +L E ++ G + W  A + + GD R+Q ++   Q+++ F  +    TQ    ERE         EA LR     ++KA+ +  + +       K   AI + KA  LLSD    + V   D RR + +D      +L+   ++EK   E    L KR  + F ++LD    +T  +TW E ++++ E+PR
Sbjct:  295 LLMEQHLDGQSRWTKARERMEGDTRFQAVESSGQREEWFRQHVEKLTQAGDSERERELERQARTEASLREREREVQKARSEQTREIDREREQHKREEAIQHFKA--LLSDMVRSSEVNWDDTRRSLRKDHRWELASLLDRSEKEKLFKEHVDALSKRKKEQFKQLLDETSEITLTSTWREVRKLIKEDPR 482          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDT-SDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMIS----GDPRYQELKKYN-QKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEW--TAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILL-----ENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLE----SFLKVIEIDERGRTLDPGNVRMAYTSLI-ERAESIEK--QRLKEVLKQQK 1701
            W E     GR YYYN +TK+STWEKP EL +  E +L E  WK  K+  GK+YYYN  T+++ W  P    + E +A   +DT S  ++N N               I  T G        +N       E+E   A+N  +   V  RTKEE E+ +  +LKE  V  ++TW  + ++IS     DPRY  +      KK++F  Y + R  D+  +      K KE  +K L N+S +     +  A  L++D P +  + V E+ +R+ ++D +  +   +KE  K L+ + +K   E L+ +   +   T+   Q++L      ++ R++ +   + +  ED L  + + +  +E D + +    + R     R  R+ F   + E+    K+ + + W D+Y  I  D RF  ML + GS+ LDLF  +V E +     ++ I ++ L D+NF ++   S E    +  KV+E D +   +D  ++ +    LI +R E I++  Q  + +L+Q+K
Sbjct:    4 WKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENGWKAAKTADGKVYYYNPTTRETSWTIPAFEKKVEPIAEQKHDTVSHAQVNGNR--------------IALTAGEKQEPGRTIN-------EEESQYANNSKLL-NVRRRTKEEAEKEFITMLKENQV--DSTWSFS-RIISELGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHIKYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKELREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVLTHEDVLNEYLKIVNTIENDLQNKLNELRLRNYTRDRIARDNFKSLLREV--PIKIKANTRWSDIYPHIKSDPRFLHMLGRNGSSCLDLFLDFVDEQRMYIFAQRSIAQQTLIDQNFEWNDADSDEITKQNIEKVLENDRKFDKVDKEDISLIVDGLIKQRNEKIQQKLQNERRILEQKK 497          

Query:  202 TEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAE 414
            TEH A DGRTY+YN  +K STW+KPDELKTP+E IL   PWKE K++ G++YY+NT T++S+W +P EL E
Sbjct:    2 TEHKAPDGRTYFYNNDSKVSTWQKPDELKTPSEIILDSFPWKEHKADSGRVYYHNTETKESIWTEPKELTE 72          

Query: 1522 DRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            D N T D ++S   F ++++ D+R  TLDPGN++MA+  LIE+AE+ EK+R K+  K+Q++ E  FKQMLK  S  ++++ SWEEV ++      F  + LE+DR++ ++EYL ++
Sbjct:    1 DCNITVDTDSSFSDFSELVQCDKRSATLDPGNIKMAFNHLIEKAEAREKERQKKEEKEQRRKESAFKQMLKAFSPALEATSSWEEVRERCEADSSFSAITLEADRIRIFQEYLASL 116          

Query:  634 VYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDER 828
            +Y TK+E ++ ++ +LKE  V   A+W+TA+++I  DPRY  LKK N+KKQ FN YKTQR  +E+
Sbjct:    5 IYATKDEAKQAFKELLKEKEVSPAASWDTAMRLIVNDPRYGALKKMNEKKQAFNEYKTQRANEEK 69          

Query:  277 DELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESS----AIDEAIKATLGSM----------PSSSDKVNSHKDSSSEDEVNPAHNIPI---PEKVVYRTK----EELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRRE-IYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVM--PNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHI 1224
            D  K  A +++    W    +  GK +++N  T+ SVW+KP EL + +K+         +EI EN    + ++S     ++D+A +    S           P S+      KD    + + PA +       EK     K    +E  + +R ++ E  V   +TWE  +  I  DPRY  L +  ++KQ F  +   R  +ER+E + ++K+ K+   K ++   K++    + +          +  + +   RE I+ + + ++ K+EKE +K+   +N KL ++  +++   NL     W + +  + ++PR+   E + +  KED  + F E +
Sbjct:  255 DRSKPVASELVPGTTWCVVWTGTGKAFFFNPATRLSVWEKPEELKDNDKV---------DEIIENGPPSREEKSKSRKLSLDDADEHQAASKRPRRESRDEPPQSTSSDVEMKDEPLREPLPPAKHTKAHRKEEKAARDRKMLPLDERMKQFREMMLERGVSAFSTWEKELPKIVFDPRYLLLNQ-KERKQCFEKFVRTRADEERQERKNKMKEKKDSF-KAMLQEMKVTVKTSFSEFAMKHGKEERFKQIEKMKERETIFLEYISELKKKEKETSKI---KNTKLHDDFFELLEEQNLEAGANWRKVKSKIEDDPRYKAVESVST--KEDYFMQFMEEL 578          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGN-NDTSDNEINENNTTDKP----------------------------KESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPI-------PE--KVVYR--TKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLK--SHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTI 1863
            WTEH + DG+TYYYN  TKQSTWEKPD+LK+PAE++LS+C WKE+KS+ GK YYYN+ T++S W KP EL + E +     N T++       T   P                              ++ + E + + +   P++  K       S+E      +   +       PE  K  Y+  TKEE ++ ++ +LKE  V  N++WE A+K+I  DPRY  L K ++KKQ FN YK Q +K+E+EEAR++ K++KE  ++FL NH K++S   Y+KA+ +  +   W+ VPERDR EIYED L  + K+EKE+AK LRKRN +    ILD M N+T++TTW EAQ+ LL+NP F EDE+LQ+MDKEDALICFEEHIR LEK+ EEEK++   R +R QRKNRE+F  F+DELH+ G+L S+S W ++Y  +S D RF  ML QPGSTPLDLFKFYV +LK+R+  EKRI+K+IL+D++F  + NTS + F  +I  D+R  TLD GN+++A+ SL+E+AE+ E++R KE  ++ K+ E  FK MLK  +  ++    WE V ++      F+ + LES+R + +K+++  +
Sbjct:  117 WTEHKSLDGKTYYYNTETKQSTWEKPDDLKSPAEQLLSKCHWKEYKSDTGKPYYYNSQTKESRWTKPKELEDLEAMIKAEENGTAETAAVTPGTAATPTVQADNTATLAAVTEVETTTAVATAAAAAAAAVVSEELPSQVSVHPAAEVKTTDAPVVSTESSAVTENTASVKVTKEEPPEIQKKTYKWNTKEEAKQAFKELLKEKGVSSNSSWEQAMKLIINDPRYSALPKLSEKKQAFNAYKVQTEKEEKEEARIKYKESKETFQRFLENHEKMTSTTRYKKAEQMFGELEVWSCVPERDRLEIYEDVLFFLAKKEKEQAKQLRKRNWEALKNILDNMANVTYRTTWSEAQQYLLDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQKFLDELHDHGQLHSMSSWMEMYPALSSDMRFANMLGQPGSTPLDLFKFYVEDLKARYHDEKRIIKDILKDKSFMVEVNTSFDDFGSIISSDKRAATLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKEAAFKTMLKQATPPLEPEALWEGVRERFVKEAAFEDITLESERKRIFKDFMHVL 713          

Query:  199 WTEHIAQDGRTYYYNLITKQSTWEKPDELK------TPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAE 420
            W E  A++G  YYYN IT +S WEKP +         P E+  S   W    S +G  YYYN  T +S W+KP + +  +
Sbjct:  139 WVEGFAENGHMYYYNTITGESQWEKPADPPGEPSTFVPPERSFSSA-WMPAVSPEGFTYYYNPETGESSWEKPADFSSGD 217          

Query:  169 NSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDEL--KTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPN--LTFKTTWYEAQRILLENPRF 1158
            N +P  P   W      D R ++YN  T+ S W++P+EL  +   +K + E P K    E GK        +  V ++ P+L+         N T D                 +DE              + ++ K+++ E E+  A      E+ +   +  + + +R +L E  V   +TW+  +  I  DPRY  L    ++KQ+F+ Y   R ++ER+E + ++ +AK++  K +M  +KL+    + +        P +  + + +DR  I+ + +  M KREKE++K    R  K+  +  D++ +  +     W + +  L  +PR+
Sbjct:  446 NPIPGTP---WCVVWTGDDRVFFYNPTTRLSMWDRPEELVGRADVDKHIQEPPHKR-GVEDGK--------KTGVIKEEPDLS---------NATED----------------ILDEEPSKAKKRKKEEQKESDTEKEAAMEAELKAAR-----ERAIVPLESRMTQ-FREMLLERGVSAFSTWDKELHKIVFDPRYLLLNP-KERKQVFDQYVKTRAEEERKEKKNKLMQAKDEFRK-MMEDAKLTPRTTFSEFALKHGRDPRFKTIEKMKDREAIFIEFMTAMRKREKEDSK---SRGEKVRQDFFDLLSDQHIDGNHRWSKVKERLETDPRY 732          

Query:   49 FGIILNGIEISMSNNYQFTLPPL-THSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKP 276
            F + L G+ I +        PP+ +  +P       P S+  SL  LPE  WTE+   DG+TYYYN  T +STWEKP
Sbjct:  309 FRVPLPGMHIPLPGMLPGMGPPIVSMMHPQLALSAAPASMAGSL-HLPE--WTEYKTADGKTYYYNNRTLESTWEKP 382          

Query:  169 NSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDEL--KTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPN--LTFKTTWYEAQRILLENPRF 1158
            N +P  P   W      D R ++YN  T+ S W++P+EL  +   +K + E P K    E GK        +  V ++ P+L+         N T D                 +DE              + ++ K+++ E E+  A      E+ +   +  + + +R +L E  V   +TW+  +  I  DPRY  L    ++KQ+F+ Y   R ++ER+E + ++ +AK++  K +M  +KL+    + +        P +  + + +DR  I+ + +  M KREKE++K    R  K+  +  D++ +  +     W + +  L  +PR+
Sbjct:  466 NPIPGTP---WCVVWTGDDRVFFYNPTTRLSMWDRPEELVGRADVDKHIQEPPHKR-GVEDGK--------KTGVIKEEPDLS---------NATED----------------ILDEEPSKAKKRKKEEQKESDTEKEAAMEAELKAAR-----ERAIVPLESRMTQ-FREMLLERGVSAFSTWDKELHKIVFDPRYLLLNP-KERKQVFDQYVKTRAEEERKEKKNKLMQAKDEFRK-MMEDAKLTPRTTFSEFALKHGRDPRFKTIEKMKDREAIFIEFMTAMRKREKEDSK---SRGEKVRQDFFDLLSDQHIDGNHRWSKVKERLETDPRY 752          

Query:  169 NSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDEL--KTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPE-RDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPN--LTFKTTWYEAQRILLENPRF 1158
            N +P  P   W      D R ++YN  T+ S W++P+EL  +   +K + E P K    E GK        +  V ++ P+L+         N T D                 +DE              + ++ K+++ E E+  A      E+ +   +  + + +R +L E  V   +TW+  +  I  DPRY  L    ++KQ+F+ Y   R ++ER+E + ++ +AK++  K +M  +KL+    + +        P +  + + +DR  I+ + +  M KREKE++K    R  K+  +  D++ +  +     W + +  L  +PR+
Sbjct:  482 NPIPGTP---WCVVWTGDDRVFFYNPTTRLSMWDRPEELVGRADVDKHIQEPPHKR-GVEDGK--------KTGVIKEEPDLS---------NATED----------------ILDEEPSKAKKRKKEEQKESDTEKEAAMEAELKAAR-----ERAIVPLESRMTQ-FREMLLERGVSAFSTWDKELHKIVFDPRYLLLNP-KERKQVFDQYVKTRAEEERKEKKNKLMQAKDEFRK-MMEDAKLTPRTTFSEFALKHGRDPRFKTIEKMKDREAIFIEFMTAMRKREKEDSK---SRGEKVRQDFFDLLSDQHIDGNHRWSKVKERLETDPRY 768          

Query:   82 MSNNYQFTLPPLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIXXXXXXXXXXXXXXXXXXXXXXXXNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHDIKSSVSWEEVCQKLGNLEDFKFVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSSREHKTNXXXXXXXXXXXXXXXXXXXXXXNNGTEDDSXXXXXXXXXXXXXXXXXXHNRQDSSSDEMGPTATVGQKPVDARQPSEGEVIDEDEPEPRQALNHPKAIVSSSAEMS 2283
            MSNNYQFTLPPLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIRLLEKDHEEEKEREKRRLKRMQRKNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHDIKSSVSWEEVCQKLGNLEDFK VELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSSREHKTNRDKPKRKKKKHSRDSSADSKDKNNGTEDDSKGKYKLHKKSKKKKKKRKHNRQDSSSDEMGPTATVGQKPVDARQPSEGEVIDEDEPEPRQ LNHPKAIVSSSAEMS
Sbjct:    1 MSNNYQFTLPPLTHSYPVPTSYLPPTSVQNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVNPAHNIPIPEKVVYRTKEELEEGWRVILKELNVPGNATWETAVKMISGDPRYQELKKYNQKKQIFNTYKTQRQKDEREEARLRIKKAKEDLEKFLMNHSKLSSAIGYRKADSLLSDCPEWTAVPERDRREIYEDTLIQMGKREKEEAKVLRKRNIKLFNEILDVMPNLTFKTTWYEAQRILLENPRFVEDEDLQSMDKEDALICFEEHIRLLEKDHEEEKEREKRRLKRMQRKNREAFAVFMDELHEKGKLTSLSMWKDLYEIISRDERFYKMLSQPGSTPLDLFKFYVLELKSRFSKEKRIVKEILEDRNFTFDFNTSLESFLKVIEIDERGRTLDPGNVRMAYTSLIERAESIEKQRLKEVLKQQKKSEFNFKQMLKSHDIKSSVSWEEVCQKLGNLEDFKSVELESDRMKYYKEYLLTIRSRSRSKFSQEIKRKRKHRSNSKESVSSREHKTNRDKPKRKKKKHSRDSSADSKDKNNGTEDDSKGKYKLHKKSKKKKKKRKHNRQDSSSDEMGPTATVGQKPVDARQPSEGEVIDEDEPEPRQVLNHPKAIVSSSAEMS 734          

Query:  109 PPLTHSYPVPTSYLPPTSVQN-------------SLPTLPEQ-AWTEHIAQDGRTYYYNLITKQSTWEKPDEL--------------KTPAEKILSECP--------------------WKEFKSEQGKIYYYNTVTQQSVWQKPPELAEAEKLAYGNNDTSDNEINENNTTDKPKESSAIDEAIKATLGSMPSSSDKVNSHKDSSSEDEVN 600
            PP  H  P      PP  +               +L TL EQ  W ++   DGR YYY   T+Q+TW++P  +              K PA   +S  P                    W E+K+  G+ Y++N  T  + W+KP  L + E           N+IN      KP E + I E  K+   S+    +KV+  KD SS DE N
Sbjct:  377 PPFAHMPPPMMGQAPPLPMHPDPNFGGNKVDKPLTLATLNEQDVWVQNPTSDGRIYYYQWKTRQTTWDRPQGVKIIIQSELDNILANKNPA--TISSAPVQLLIPNIAPQPTKPPEVVEWNEYKAPDGRPYFHNRRTAVTTWEKPQVLIDWE-----------NKIN----GVKPAEPAPIPE--KSISKSVEIEENKVDDSKDESS-DESN 568          

Query:  166 QNSLPTLPEQAWTEHIAQDGRTYYYNLITKQSTWEKPDELKTPAEKILSECPWKEFKSEQGKIYYYNTVTQQSVWQKPPELA---EAEKLAYGNNDTSDNEINENNTT-DKPKESSAIDEAIKATLGSMPSSSDKVNS 567
            +NS   +    W E + Q+GR YY +  +K++ WEKP   + P         W+E     G++YY +   Q++ W+ P   +   +  KLA  N   ++N ++    +  +P  SS +D A         S  D V S
Sbjct:  203 ENSTAEVLANGWEERVDQNGRIYYVDHKSKRTQWEKPTNAQLPEG-------WEERADLSGRVYYVDHANQKTQWEHPASKSAPQKVNKLAKINMPAANNPLSVRAVSPTRPGPSSDVDAATMFLRRRQISHEDTVAS 333