TNF receptor associated factor-2

Overview
NameTNF receptor associated factor-2
Smed IDSMED30029882
Length (bp)1500
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TNF receptor associated factor-2 (SMED30029882) t-SNE clustered cells

Violin plots show distribution of expression levels for TNF receptor associated factor-2 (SMED30029882) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TNF receptor associated factor-2 (SMED30029882) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TNF receptor associated factor-2 (SMED30029882) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029882

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
testisSMED30029882h1SMcG0019679 SMED30029882smed_20140614PMID:279364
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
intestinal phagocyteSMED30029882h1SMcG0018978 Contig1145GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30029882h1SMcG0019679 PL06023A1G07smed_ncbi_20240424PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30029882h1SMcG0019679 Contig1145GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30029882h1SMcG0019679 PL08009B2A08smed_ncbi_20240424PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30029882h1SMcG0019679 dd_Smed_v4_5715_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30029882h1SMcG0019679 dd_Smed_v4_5715_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30029882h1SMcG0019679 dd_Smed_v4_5715_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF1 (TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031])

HSP 1 Score: 67.781 bits (164), Expect = 6.572e-12
Identity = 51/235 (21.70%), Postives = 104/235 (44.26%), Query Frame = 3 
Query:  615 IKEINQKIPEIGVPVAFNIQIENMN-QKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGC-FLMDLDEVLN-DSEWKKEDKFFVNCIISTN 1307
            +  +N+++    + +A +I    ++ ++  + E+ + EL+    ++   +GK + +  L+                 E +    +LWK   +  +  ++  G+     S  F T+K GY++ L+L  N   +G +  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC     L ++ +    + K+D  F+ CI+ T+
Sbjct:   79 VAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQQTLAQKDQALGKLEQSLRLME----------------EASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETS 293
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF1 (TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031])

HSP 1 Score: 68.1662 bits (165), Expect = 1.207e-11
Identity = 42/151 (27.81%), Postives = 70/151 (46.36%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTN 1307
            +LWK   +  +  ++  G+     S  F T+K GY++ L+L  N   +G +  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC L      L   +  + K+D  F+ CI+ T+
Sbjct:  269 FLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETS 415
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF1 (TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031])

HSP 1 Score: 68.1662 bits (165), Expect = 1.207e-11
Identity = 42/151 (27.81%), Postives = 70/151 (46.36%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTN 1307
            +LWK   +  +  ++  G+     S  F T+K GY++ L+L  N   +G +  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC L      L   +  + K+D  F+ CI+ T+
Sbjct:  269 FLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETS 415
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 65.0846 bits (157), Expect = 1.529e-10
Identity = 81/396 (20.45%), Postives = 171/396 (43.18%), Query Frame = 3 
Query:  216 YCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEK-------EFWTNTLAFFKANIDA-------NQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQ-IENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSL-KNEFIVNPEPIKPNEKNICVQYL----------WKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            Y       C+S++ ++ L  ++DT        ++V CP++ CS    L +   + ++           +      +++N+LK     L++ ++  Q E        +   N +  F+  I+        N+ +I +LQ   +    ++KE++++I     P   N +  ++M    ++ +  + EL +   K + +V +   T  L + L +++ +++   I+  + ++  Q L          WK      + ++ + GK     S  F T   GY++  R+ L  +    G  L ++    IM+G++D  L WPF+  +T  L++      Q S   +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  172 YREATCSHCKSQVPMIALQKHEDT----DCPCVVVSCPHK-CSVQTLLRSEGTNQQI---------KAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIR----PFRQNWEEADSMKSSVESLQNRVTELES-VDKSAGQVARN--TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF--FVIMRGEYDALLPWPFKQKVTLMLMD------QGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 538
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 65.0846 bits (157), Expect = 1.529e-10
Identity = 81/396 (20.45%), Postives = 171/396 (43.18%), Query Frame = 3 
Query:  216 YCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEK-------EFWTNTLAFFKANIDA-------NQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQ-IENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSL-KNEFIVNPEPIKPNEKNICVQYL----------WKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            Y       C+S++ ++ L  ++DT        ++V CP++ CS    L +   + ++           +      +++N+LK     L++ ++  Q E        +   N +  F+  I+        N+ +I +LQ   +    ++KE++++I     P   N +  ++M    ++ +  + EL +   K + +V +   T  L + L +++ +++   I+  + ++  Q L          WK      + ++ + GK     S  F T   GY++  R+ L  +    G  L ++    IM+G++D  L WPF+  +T  L++      Q S   +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  172 YREATCSHCKSQVPMIALQKHEDT----DCPCVVVSCPHK-CSVQTLLRSEGTNQQI---------KAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIR----PFRQNWEEADSMKSSVESLQNRVTELES-VDKSAGQVARN--TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF--FVIMRGEYDALLPWPFKQKVTLMLMD------QGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 538
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429)

HSP 1 Score: 51.6026 bits (122), Expect = 1.173e-6
Identity = 30/103 (29.13%), Postives = 47/103 (45.63%), Query Frame = 3 
Query:  867 LWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHP 1175
            LWK    +AK+ +       E +S  F TS+ GY+++  +  N    G    V   + ++ G++D  L WPF + ITF L    +   Q  Q     + VP P
Sbjct:  334 LWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLF---EQGAQSGQGGVAESFVPDP 433
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401)

HSP 1 Score: 50.8322 bits (120), Expect = 1.777e-6
Identity = 30/103 (29.13%), Postives = 47/103 (45.63%), Query Frame = 3 
Query:  867 LWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHP 1175
            LWK    +AK+ +       E +S  F TS+ GY+++  +  N    G    V   + ++ G++D  L WPF + ITF L    +   Q  Q     + VP P
Sbjct:  325 LWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLF---EQGAQSGQGGVAESFVPDP 424
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 75.0998 bits (183), Expect = 5.640e-14
Identity = 43/147 (29.25%), Postives = 71/147 (48.30%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK  + + + +D +AG+     S  F +SK GY++ L+L  N   +G    +     +MKGK+D  L WPF   +T  L+    D+  +   I  F   V      RPI  MN+  GC L   L ++   S + ++D  F+  I+
Sbjct:  385 FIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLL----DQNNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 527

HSP 2 Score: 51.2174 bits (121), Expect = 2.008e-6
Identity = 30/95 (31.58%), Postives = 45/95 (47.37%), Query Frame = 3 
Query:  114 CVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEII------ILNLNTN-KDTAINRKISKMIVRCPNETCSFSDELVNMDNH 377
            C  CK +L+  +   CG R+C  C    ++   I C      CR+E I      +LN+     D A  R+I  +  +CPNE CS+S  L + +N 
Sbjct:   45 CQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEA----CRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQ 135
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 75.0998 bits (183), Expect = 5.640e-14
Identity = 43/147 (29.25%), Postives = 71/147 (48.30%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK  + + + +D +AG+     S  F +SK GY++ L+L  N   +G    +     +MKGK+D  L WPF   +T  L+    D+  +   I  F   V      RPI  MN+  GC L   L ++   S + ++D  F+  I+
Sbjct:  385 FIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLL----DQNNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 527

HSP 2 Score: 51.2174 bits (121), Expect = 2.008e-6
Identity = 30/95 (31.58%), Postives = 45/95 (47.37%), Query Frame = 3 
Query:  114 CVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEII------ILNLNTN-KDTAINRKISKMIVRCPNETCSFSDELVNMDNH 377
            C  CK +L+  +   CG R+C  C    ++   I C      CR+E I      +LN+     D A  R+I  +  +CPNE CS+S  L + +N 
Sbjct:   45 CQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEA----CRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQ 135
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 75.0998 bits (183), Expect = 5.896e-14
Identity = 43/147 (29.25%), Postives = 71/147 (48.30%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK  + + + +D +AG+     S  F +SK GY++ L+L  N   +G    +     +MKGK+D  L WPF   +T  L+    D+  +   I  F   V      RPI  MN+  GC L   L ++   S + ++D  F+  I+
Sbjct:  398 FIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLL----DQNNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 540

HSP 2 Score: 51.2174 bits (121), Expect = 1.965e-6
Identity = 30/95 (31.58%), Postives = 45/95 (47.37%), Query Frame = 3 
Query:  114 CVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEII------ILNLNTN-KDTAINRKISKMIVRCPNETCSFSDELVNMDNH 377
            C  CK +L+  +   CG R+C  C    ++   I C      CR+E I      +LN+     D A  R+I  +  +CPNE CS+S  L + +N 
Sbjct:   58 CQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEA----CRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQ 148
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: BX901915.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:28768979:-1 gene:ENSDARG00000109857.1 transcript:ENSDART00000191629.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX901915.1)

HSP 1 Score: 67.3958 bits (163), Expect = 5.465e-12
Identity = 39/147 (26.53%), Postives = 69/147 (46.94%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK    + K +D +AG+     S  F TSK GY++ L++  N   +G    +     +M+G  D  L WPF   +T  L+    D+  +   I  F   +      RP+  MN+  GC L   L ++ + + + ++D  F+  I+
Sbjct:  128 FVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLL----DQNNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 270
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: AL844899.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28760787:-1 gene:ENSDARG00000111038.1 transcript:ENSDART00000183806.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844899.1)

HSP 1 Score: 67.3958 bits (163), Expect = 5.465e-12
Identity = 39/147 (26.53%), Postives = 69/147 (46.94%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK    + K +D +AG+     S  F TSK GY++ L++  N   +G    +     +M+G  D  L WPF   +T  L+    D+  +   I  F   +      RP+  MN+  GC L   L ++ + + + ++D  F+  I+
Sbjct:  128 FVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLL----DQNNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 270
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: hspb6 (heat shock protein family B (small) member 6 [Source:Xenbase;Acc:XB-GENE-876273])

HSP 1 Score: 78.1814 bits (191), Expect = 4.552e-15
Identity = 48/152 (31.58%), Postives = 74/152 (48.68%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINP-CKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTNK 1310
            +LWK   +  K  D + G+     S  F T+K GY++ L++  N   +G    V     +MKG++D  L WPF++ +TF L++   +D V  +    F   V      RPI  MNV  GC L      LN  +  + +E+  ++ CII TN 
Sbjct:  232 FLWKISDLTNKSHDAVTGRAISLYSPAFYTAKYGYKVCLRIYLNGDGAGKGTHVSLFFTVMKGEYDALLPWPFKHKVTFVLVDHNNRDSVFDA----FRPDVTSASFQRPINDMNVASGCPLFCPIAKLNSPKHAYIRENTLYIRCIIDTNS 379
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415])

HSP 1 Score: 64.3142 bits (155), Expect = 1.775e-10
Identity = 40/147 (27.21%), Postives = 67/147 (45.58%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK  +   K +D + G+     S  F T+K GY++ L++  N   +G    +     +MKG  D  L WPF   +T  L+    D+  +   I  F   V      RPI  MN+  GC L   + ++   + + ++D  FV  I+
Sbjct:  307 FIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLL----DQNNREHVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIV 449
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415])

HSP 1 Score: 63.1586 bits (152), Expect = 4.886e-10
Identity = 40/147 (27.21%), Postives = 67/147 (45.58%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK  +   K +D + G+     S  F T+K GY++ L++  N   +G    +     +MKG  D  L WPF   +T  L+    D+  +   I  F   V      RPI  MN+  GC L   + ++   + + ++D  FV  I+
Sbjct:  334 FIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLL----DQNNREHVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIV 476
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 62.003 bits (149), Expect = 1.162e-9
Identity = 68/377 (18.04%), Postives = 157/377 (41.64%), Query Frame = 3 
Query:  240 CRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWN-------LQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQYL----------WKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            CR+++ ++ +  ++D         +++ CP+  CS    L +   + ++          V +  L  E  N L+ ++  L+   ++     +   N +  F+  I+ ++ Q+ N       LQ        ++K+++++I  +        + + M   Y++ +  + +L    + ++     P   E  +N  +++ +++   I+  + ++  Q L          WK      + ++ + GK     S  F T   GY++  ++  N    G    +     IM+G++D  L WPF+  ++  L++      Q     +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  175 CRNQVPLVEMQKHEDV----DCPSVVISCPH-MCSVKSLLRSEGTNQQI--KAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLR---QTGDEADGMKSNYESLQNRLSQLE--VMAKNAASWNPGVLETQIN--RHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMD------QGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 531
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 61.2326 bits (147), Expect = 2.120e-9
Identity = 36/151 (23.84%), Postives = 67/151 (44.37%), Query Frame = 3 
Query:  867 LWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            +WK      + ++ + GK     S  F T   GY++  ++  N    G    +     IM+G++D  L WPF+  ++  L++      Q     +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  412 IWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMD------QGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 556
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf1 (TNF receptor-associated factor 1 [Source:MGI Symbol;Acc:MGI:101836])

HSP 1 Score: 70.8626 bits (172), Expect = 9.126e-13
Identity = 44/151 (29.14%), Postives = 71/151 (47.02%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTN 1307
            +LWK   +  +  +++ G+     S  F T+K GY++ L+L  N   SG K  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC L      L   +  + K+D  F+ CI+ T+
Sbjct:  262 FLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVDTS 408
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf1 (TNF receptor-associated factor 1 [Source:MGI Symbol;Acc:MGI:101836])

HSP 1 Score: 70.8626 bits (172), Expect = 9.126e-13
Identity = 44/151 (29.14%), Postives = 71/151 (47.02%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTN 1307
            +LWK   +  +  +++ G+     S  F T+K GY++ L+L  N   SG K  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC L      L   +  + K+D  F+ CI+ T+
Sbjct:  262 FLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVDTS 408
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf1 (TNF receptor-associated factor 1 [Source:MGI Symbol;Acc:MGI:101836])

HSP 1 Score: 70.8626 bits (172), Expect = 9.126e-13
Identity = 44/151 (29.14%), Postives = 71/151 (47.02%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTN 1307
            +LWK   +  +  +++ G+     S  F T+K GY++ L+L  N   SG K  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC L      L   +  + K+D  F+ CI+ T+
Sbjct:  262 FLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVDTS 408
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 65.4698 bits (158), Expect = 7.782e-11
Identity = 80/397 (20.15%), Postives = 167/397 (42.07%), Query Frame = 3 
Query:  216 YCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEK-------EFWTNTLAFFKANIDA-------NQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQ-IENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSL--KNEFIVNPEPIKPNEKNICVQYL----------WKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            Y       C+S++ ++ L  ++DT        ++V CP++ CS    L +   + ++           +      +++N+LK     L++ ++  Q E        +   N +  F+  I+        N+ +I +LQ   +    ++KE++++I     P   N +  ++M    ++ +  + EL +         G+      LL S   +++ +++   I+  + ++  Q L          WK      + ++ + GK     S  F T   GY++  R+ L  +    G  L ++    IM+G++D  L WPF+  +T  L++      Q S   +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  171 YREATCSHCKSQVPMIKLQKHEDT----DCPCVVVSCPHK-CSVQTLLRSEGTNQQI---------KAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIR----PFRQNWEEADSMKSSVESLQNRVTELESV----DKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF--FVIMRGEYDALLPWPFKQKVTLMLMD------QGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 537
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 65.4698 bits (158), Expect = 7.782e-11
Identity = 80/397 (20.15%), Postives = 167/397 (42.07%), Query Frame = 3 
Query:  216 YCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEK-------EFWTNTLAFFKANIDA-------NQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQ-IENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSL--KNEFIVNPEPIKPNEKNICVQYL----------WKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            Y       C+S++ ++ L  ++DT        ++V CP++ CS    L +   + ++           +      +++N+LK     L++ ++  Q E        +   N +  F+  I+        N+ +I +LQ   +    ++KE++++I     P   N +  ++M    ++ +  + EL +         G+      LL S   +++ +++   I+  + ++  Q L          WK      + ++ + GK     S  F T   GY++  R+ L  +    G  L ++    IM+G++D  L WPF+  +T  L++      Q S   +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  171 YREATCSHCKSQVPMIKLQKHEDT----DCPCVVVSCPHK-CSVQTLLRSEGTNQQI---------KAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIR----PFRQNWEEADSMKSSVESLQNRVTELESV----DKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF--FVIMRGEYDALLPWPFKQKVTLMLMD------QGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 537
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q3ZCC3|TRAF6_BOVIN (TNF receptor-associated factor 6 OS=Bos taurus OX=9913 GN=TRAF6 PE=2 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 3.065e-14
Identity = 102/465 (21.94%), Postives = 177/465 (38.06%), Query Frame = 3 
Query:   96 FDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNH-----------------MKVCNLGVTLDEMVNNTRLQSENINI-LKVELKELKQTMNKYQTEKEFWTNTLAF--------------------FKANIDANQMQ----IWNLQENQN---RLCAQIKEI----NQKIPEIGVPVAFNIQ----IENMNQKYQNFEKSIEELRNYFIKQSDEV----GKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQ-YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCI--MKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNV-GLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
             +S+  C IC   L+ A   PCG R+C  CI          CP +     +EI++ N     D    R+I  ++V+CPNE C    EL +++ H                  + C+L + + +     ++  EN  + +  E KE+ +           + NT+                      F A     +MQ      +LQEN     R+ AQ  +        +P+  +P+  ++         + +  NF+++I++L    ++Q  ++     K +     +N LK       + +   E   C   Y+WK       LK     K     S  F T K GY++ ++L   +  S  +   Y SL +  M+G++D  L WPF+  I   +++  +  V+++               RP    N  G G       E L    + K+D   V C +ST 
Sbjct:   65 LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD-----NEILLEN-QLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEEHQAHCEFALMSCPQCQRPFQKCHLNIHILKECPRRQVPCENCAVSMAFEDKEIHEQNCPLANVICEYCNTMLIREQMPNHYDLDCPTAPVPCTFSAFGCHEKMQRNHLARHLQENTQSHMRMMAQAVQTLSLAVAPVPQCTMPLYDSVPPTRPSSGRHSEVHNFQETIQQLEGRLVRQDHQIRELTAKMETQSMYVNELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQL-PSAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAAVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTR 522
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|P39428|TRAF1_MOUSE (TNF receptor-associated factor 1 OS=Mus musculus OX=10090 GN=Traf1 PE=1 SV=2)

HSP 1 Score: 70.8626 bits (172), Expect = 6.384e-12
Identity = 44/151 (29.14%), Postives = 71/151 (47.02%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTN 1307
            +LWK   +  +  +++ G+     S  F T+K GY++ L+L  N   SG K  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC L      L   +  + K+D  F+ CI+ T+
Sbjct:  262 FLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVDTS 408
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q13077|TRAF1_HUMAN (TNF receptor-associated factor 1 OS=Homo sapiens OX=9606 GN=TRAF1 PE=1 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.798e-11
Identity = 42/151 (27.81%), Postives = 70/151 (46.36%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSE--WKKEDKFFVNCIISTN 1307
            +LWK   +  +  ++  G+     S  F T+K GY++ L+L  N   +G +  +   + IM+G++D  L WPF   +TF L+    D+  +   I  F   +      RP    NV  GC L      L   +  + K+D  F+ CI+ T+
Sbjct:  269 FLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL----DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETS 415
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2)

HSP 1 Score: 63.929 bits (154), Expect = 1.544e-9
Identity = 40/153 (26.14%), Postives = 71/153 (46.41%), Query Frame = 3 
Query:  867 LWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            +WK      + ++ + GK     S  F T   GY++  R+ L  +    G  L ++    IM+G++D  L WPF+  +T  L++      Q S   +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  418 IWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF--FVIMRGEYDALLPWPFKQKVTLMLMD------QGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 562
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2)

HSP 1 Score: 63.929 bits (154), Expect = 1.559e-9
Identity = 40/153 (26.14%), Postives = 71/153 (46.41%), Query Frame = 3 
Query:  867 LWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            +WK      + ++ + GK     S  F T   GY++  R+ L  +    G  L ++    IM+G++D  L WPF+  +T  L++      Q S   +  ++  P P  +   +P G MN+  GC +     VL +  + K+D  F+  I+ T+
Sbjct:  419 IWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF--FVIMRGEYDALLPWPFKQKVTLMLMD------QGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTS 563
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 5.914e-18
Identity = 41/94 (43.62%), Postives = 60/94 (63.83%), Query Frame = 3 
Query:  114 CVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNL 395
            C +CK LL NA    CGCR+C +CI  Y +   +YCPG   EC+ E + +  N + D  +NRKI+KM V+CP ETC    ELV+++ H+++C +
Sbjct:   27 CDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTM 120
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: A0A093FV74 (TNF receptor-associated factor 2 (Fragment) OS=Gavia stellata OX=37040 GN=N328_06817 PE=4 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 7.520e-18
Identity = 109/481 (22.66%), Postives = 185/481 (38.46%), Query Frame = 3 
Query:   99 DSEVICVICKTLLQNAYSGPCGCRYCYECISH-YSNGPEIYC-------PGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVT-------------------LDEMVNN-TRLQSENINILKVELKELKQTMNKYQTEKEF-WTNTL--------------------AFFKAN-----------IDANQMQIW-NLQENQNRLCAQIKEINQKIPEIGVPV-------------AFNIQIENMNQKYQNFEKSIEE----LRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGC-FLMDLDEVLNDS-EWKKEDKFFVNCII 1298
            D + +C  C  +L+ A    CG RYC  C+S    N   + C       P  L E     ++       D AIN++IS++ V C    CS+S  + N + H  +C   +                     +E VNN T  Q    N    E +E  Q  +     + F WT  L                      F+ +           + A+ + +  ++++ +  LC   K  N  IP+  + V               N ++E  N +   F +  E     +R   +K ++        +  L+SL    +++ +            +LWK   +  KL+D++ G+     S  F T+K GY++ L++  N   +G    +     +MKG +D  L WPF + +TF L+    D+  +   I  F   +      RP+  MNV  GC   + L ++ +    + KED  F+ CII
Sbjct:    4 DQKYLCSNCNNILKKALQTLCGHRYCSACLSWIVRNNKNVICQKCKEEDPSTLSEGS---LLAEERAFGDAAINKEISELKVHCVTLGCSWSGIMKNFEEHQSLCEYALIPCHTGCGHMVMRKKLADHLENECVNNVTMCQKCKRNFSSSEYQEHHQRKSFISIHRSFTWTFRLNQHLRTSSDMADGCRFSEVGCSFRGSKEKIKEHERTAVGAHMLLLLQHIKQLKASLCTSAKAANGSIPQSELNVNENKLHVFENIVAVLNKEVETSNLEITAFRRQSELDQNIIRGLELKIAELHRCLTQKDAGLSSLHKSLLISEQASYDG------VFLWKITDVGRKLQDSVTGRTVSLYSPAFYTAKYGYKVCLRVYLNGDGTGKGTHLSLFFVVMKGDYDALLPWPFRHKVTFMLL----DQNNREHIIDAFRPDLTSASFQRPVNDMNVASGCPMFLPLSKLQSPKYAYVKEDTLFLKCII 471
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: A0A1S3K6C1 (TNF receptor-associated factor 2 OS=Lingula unguis OX=7574 GN=LOC106179037 PE=4 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 4.819e-17
Identity = 84/373 (22.52%), Postives = 162/373 (43.43%), Query Frame = 3 
Query:  114 CVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDEL-VNMDNHMKVC-NLGVTLDEMVNNT---RLQSE-----NINILKVELKEL-KQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNE-------------------KNICVQ----------YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELIN 1112
            C  C+ +L++A   PCG R+C  C+    +G    CP + PE      + +     D A+ R++ +++V C    C ++ +L     NH + C +  VT  E  ++    +LQ+E      ++ ++  +++L K+  +K QT  E  T  +   +  +   ++Q+  L+E       ++ EIN++ P      +  +++E M    +  E  +  L       + ++ K   T  LL S +    V  E +K +E                   +++ +Q          +LWK  +++ K  D ++G+     S  F TS  GY++  +L  N    G    V     +M+G +D  L WPF+  +T  L++
Sbjct:  274 CRSCQLVLRDAVQTPCGHRHCAGCVERSRSGGGRLCP-DCPEIDE---MDDRQIYPDMAVRREVHRLLVACRQTGCDWTGDLKTYQQNHERSCLSRRVTTSEDDSSDAICKLQTEAAMLAQMDEIRQRVEDLQKEVGHKQQTGVEAMTRRVGEMEVGLQECRVQVQQLEE-------KVVEINRREPSTPGESS-TVRVEQMRDNLKTLEHKLSTLEGMVAAIARDIEK---TSALLESQEATRRVQEERLKSSEDKVKALERVIALRDISMAEQDLRIQALESASYNGVFLWKITEVSRKRHDAVSGRVSSLYSPAFYTSAHGYKMCCRLYLNGDGMGKGTHVSLFFVVMRGHYDALLRWPFKQKVTCILLD 631
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: T0MIZ1 (TNF receptor-associated factor OS=Camelus ferus OX=419612 GN=CB1_056579004 PE=3 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 1.845e-16
Identity = 100/425 (23.53%), Postives = 167/425 (39.29%), Query Frame = 3 
Query:   96 FDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNT--RLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPV----------AFNIQIEN-MNQKYQNFEKSIEELRNYFIKQSDEV----GKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQ-YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCI--MKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNV-GLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
             +S+  C IC   L+ A   PCG R+C  CI          CP +     +EI++ N     D    R+I  + V+CPNE C    EL +++ H + C L   + E  N    R Q  N   L      +  T + +   ++   N LA              +LQEN       + +  QK+     PV           F  ++ +  + + QNF+++I++L    ++Q  ++     K +     +N LK       + +   E   C   Y+WK       LK     K     S  F T K GY++ ++L   +  +  +   Y SL +  M+G++D  L WPF+  I   +++  +  ++++               RP    N  G G       E L    + K+D   V C +ST 
Sbjct:   43 LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD-----NEILLEN-QLFPDNFAKREILSLTVKCPNEGCLHKMELRHLEIHDQNCPLANVICEYCNTMLIREQIPNHYDLDCPTAPVPCTFSTFGCHEKMQRNHLA-------------RHLQENTQSHMRMLAQAVQKLSLAEAPVPQREMLPYESPFVSRVSSGCHSEVQNFQETIQQLEGRLVRQDHQIRELTAKMETQSMYVNELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQL-PTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPIRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTR 447
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 2.077e-16
Identity = 91/397 (22.92%), Postives = 168/397 (42.32%), Query Frame = 3 
Query:   99 DSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLG------VTL-----------------DEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPE-----IGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEK-----------------NICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYF 1154
            +++++C++C  L+++A    CGC YCY CI  Y +    YCPG+  EC+ + + L  +  ++  ++ +IS+++V+CPN  C+++ EL+ +  H+  C         VT+                 D+++ +T+L     N LK E+    +T    + +       L   KA  D    Q+  L E        I  ++Q I E     I +  +   +++ +    Q F + IE     F+K   EV      +  +  LK E       I  N +                 N+ + ++W+ ++ + K +        +  SD+FQ+         K   N+Y  G  L ++    IMKG+ D  L WP    +T  +I   +D ++  +T  F
Sbjct:   26 NNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEINHNNETT---KEDISHLKEVLRVQKALNDEKTAQMEFLIEELRNKDNMILVLSQDIQEVKNEMITLLTSKESELKKLKSDIQIFRQEIE-----FMKNDLEVVGSTDIKNQVKDLKKEIFGIKMNIDSNNEERERKMNNLIRLNKLCPNVDMDFMWRIEEYSKKRRTV-----TDVYSDSFQSHN------YKFCLNLYIYGDNLGLW--CVIMKGEKDDFLEWPMRRTVTLSIIE--QDSLKTHKTTVF 399
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261])

HSP 1 Score: 74.3294 bits (181), Expect = 1.037e-13
Identity = 42/147 (28.57%), Postives = 70/147 (47.62%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK    + + +D LAG+     S  F +SK GY++ L+L  N   +G    +     +M+GK+D  L WPF   +T  L+    D+  +   I  F   +      RPI  MN+  GC L   L ++   S + ++D  F+  I+
Sbjct:  384 FVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLL----DQNNREHIIDAFRPDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 526
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 71.2478 bits (173), Expect = 8.314e-13
Identity = 45/150 (30.00%), Postives = 75/150 (50.00%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSL--CIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGC-FLMDLDEVLNDSE-WKKEDKFFVNCII 1298
            +LW+   ++ KLK+   G+K    S  F TS+ G+++ ++L   +Y  G     + SL   IMKG +D  L WPF+  +TF LI    D+ Q+   +  F   +      RP+  MNV  GC     L ++ +    + K+D  F+ C++
Sbjct:  371 FLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLY--MYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLI----DQNQREHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVV 514
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 71.2478 bits (173), Expect = 9.168e-13
Identity = 45/150 (30.00%), Postives = 75/150 (50.00%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSL--CIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGC-FLMDLDEVLNDSE-WKKEDKFFVNCII 1298
            +LW+   ++ KLK+   G+K    S  F TS+ G+++ ++L   +Y  G     + SL   IMKG +D  L WPF+  +TF LI    D+ Q+   +  F   +      RP+  MNV  GC     L ++ +    + K+D  F+ C++
Sbjct:  394 FLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLY--MYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLI----DQNQREHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVV 537
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375])

HSP 1 Score: 67.3958 bits (163), Expect = 1.145e-11
Identity = 39/147 (26.53%), Postives = 69/147 (46.94%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK    + K +D +AG+     S  F TSK GY++ L++  N   +G    +     +M+G  D  L WPF   +T  L+    D+  +   I  F   +      RP+  MN+  GC L   L ++ + + + ++D  F+  I+
Sbjct:  312 FVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLL----DQNNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 454
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375])

HSP 1 Score: 67.3958 bits (163), Expect = 1.701e-11
Identity = 39/147 (26.53%), Postives = 69/147 (46.94%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK    + K +D +AG+     S  F TSK GY++ L++  N   +G    +     +M+G  D  L WPF   +T  L+    D+  +   I  F   +      RP+  MN+  GC L   L ++ + + + ++D  F+  I+
Sbjct:  425 FVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLL----DQNNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 567
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BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 3.022e-11
Identity = 39/153 (25.49%), Postives = 67/153 (43.79%), Query Frame = 3 
Query:  867 LWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTNK 1310
            +WK      + +D ++G+     S  F TS  GY +  R  L  +    G  L ++    +M+G++D  L WPF   +T  L++    + Q S T       P P  +   RP   MN+  GC L      L  + + ++D  F+  ++ T +
Sbjct:  328 VWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLF--FVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFK-----PDPASSSFRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVVDTGE 473
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.3882 bits (150), Expect = 8.375e-11
Identity = 48/211 (22.75%), Postives = 82/211 (38.86%), Query Frame = 3 
Query:  705 FEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICV--------QYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEI--RLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCII 1298
              + +  LR         +G P P E   +  +    ++   +   E+ + V        + +WK      + ++  +G+     S  F TS  GY++  R  L  +    G  L ++    +M+G++D  L WPF   +T  L++    +   S T       P P      RP G MNV  GC L      L  S +  +D  FV  ++
Sbjct:  209 LRRDMATLRERLRALEAALGNPGPCEERCHMHEQRLTMHDGLLDTAERRLQVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLF--FVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTF-----TPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVV 412
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO48394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJK8])

HSP 1 Score: 91.2781 bits (225), Expect = 9.648e-20
Identity = 116/489 (23.72%), Postives = 188/489 (38.45%), Query Frame = 3 
Query:   99 DSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIY-CPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKV------------CNLGV--TLDEMVNNT---------------------RLQSEN---INILKVELKELKQTMNKYQTEKEFWTNT-----LAFFKANIDANQMQIWNL--------QENQNRLCAQIKEINQKIPEIGVPVAFNI-QIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNIC-------VQY-----LWKFDQINAKLKDTLAGKKKE-------------------FLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRT--RPIGSMNVGLG--CFLMDLDEVLNDSEWKKEDKFFVNCIIS 1301
            + E+IC IC  ++       CG  YC  CI  + NG E+  CP +  + +   I        D   +R +  + V+C N  C +  EL     H+K+            CN+ V   L E   NT                      +Q ++   +  L     E+  T    ++ ++    +     L      I  N+ QI +L        QE Q + C  +KE+N    +    +  N  QIE +++++     +I E +                   L++LK E  +  E I+ N   I         QY     +W+      K K  +A    +                    +S  F TS+ GY++RLK   N Y  G    +  S+ IMKG++D  L WPF   IT  LIN  +    ++  IY  ++ P       RPI + NVG G  CF+  ++  LN  ++ K+D  F+  +I+
Sbjct:   25 NDELICAICHMVVNEPVLTSCGHSYCKYCIEKWCNGKEVVTCPVDNEQLKPSQIF------PDKKTDRIVLSLEVKCTNNPCRWKGELRQKQKHLKICSHKAVKCILEGCNVKVPRILMEKHTNTCGWRLLHCKPCNLSYPKKDEETVQHKDDCPLAFLPCRFSEIGCTFKGRESARDEHCESAVQTHLHIACETIRDNKEQISDLHKELDKVRQELQTKSCDHMKEVNAIREKHDEAIRDNKGQIEALSKEHGIASNTIHENKEQ-----------------LDTLKKELGIASETIRKNRDQIAKLSTACKTQYTDGTFVWRICNYKDKYKKAVAFATNQEVKGGNSDSDDDISMAGDIMVSLPFYTSRYGYKMRLKAYPNGYGDGKGTHLSLSIRIMKGEYDAILEWPFRRKITLSLINQSEQWRSETVEIYPDDATPDKKHKFERPIENENVGCGYSCFISHME--LNSGDYIKDDVIFIEAVIT 488
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO49545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGK7])

HSP 1 Score: 70.0922 bits (170), Expect = 5.592e-13
Identity = 79/351 (22.51%), Postives = 143/351 (40.74%), Query Frame = 3 
Query:  282 DTAINRKISKMIVRCPN--ETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKEL--KQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNE-KNICVQ--YLWKFDQINAKLKDTLAGKKK-EFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRT--RPIGSMNVGLG--CFLMDLDEVLNDSEWKKEDKFFVNCII 1298
            D A  R I  + V+C N    C ++ EL N++ H K C                 E+++    E  E+  ++++  +   K  W      F       +M  +   +   + C ++      I  +    A +I  E M         ++       I    +  +    E   N++     +  + I+ NE +++C    +LWK      +    +A  ++    S  F TS+ GY++RLK   N    G    +   + IMKG +D  L WPF+  ITF LI+  + +  ++  +    S+P+      RP    N+G+G  CF+   +EVL   E+ K+D  F+  ++
Sbjct:   79 DKAARRAILGLGVKCWNWKRKCEWTGELSNIEEHAKNC---------------AHEDVHCTNPECNEVMPRRSLQYHLVSKCKWRIVSCHF-----CTEMYTYKDGKTHMKSCKRLP-----IECVNKCGAKDIPREEMPFHMSECPLAVHPCMYRDIGCPFKGRRDALEEHCKNAVHTHLNIACQKIRENESRSLCTNGIFLWKISNYKHQYDQAVASPEELAIFSPPFYTSQYGYKLRLKAYLNGRDRGKGTHLSLYIIIMKGDYDALLEWPFKQKITFYLIDQSEKQNHRTHLLSPNRSLPNIKVVFNRPTVKENLGIGNPCFVP--NEVLESGEYVKDDVMFIKAVV 402
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO32851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV5])

HSP 1 Score: 64.6994 bits (156), Expect = 3.614e-11
Identity = 41/146 (28.08%), Postives = 61/146 (41.78%), Query Frame = 3 
Query:  861 QYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVP----HPGRTRPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFV 1286
            Q +W+ +    K+K+  AG      S TF TSK GY +   +  N    G    +   + ++KG FD  L WPF+Y +TF L++   D  Q+    +     P     P   RP    N   G       E +    + KED  F+
Sbjct:  303 QLIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQNDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNASFGGAKFAKHEEIVSRNYIKEDTIFL 448
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO31692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX78])

HSP 1 Score: 64.3142 bits (155), Expect = 3.709e-11
Identity = 93/429 (21.68%), Postives = 162/429 (37.76%), Query Frame = 3 
Query:  105 EVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIY-CPGNLPECRSEIIILNLNTNK---DTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGV---TLDEMVNNTRLQSENI---------NILKVELKELKQTMNKYQTEKEFWTNTLAF-----------FKANIDANQMQIWN-LQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRT--RPIGSMNVGLGCFLMDLD-EVLNDSEWKKEDKFFVNCII 1298
            E++C IC  ++       CG  YC  C + + NG ++  CP +  +         L TN+   D    R++  + V+C N  CS+  EL +   H+  C+  V     D    +TRL   ++          I+  E  ++     + +T K      LA            F+    A+     N LQ + +  C  I++ N+             +I   N+K ++  K IE L       +  + K                     +K     +   ++W+        KD      +E  S +F TSK GY+++LK   +      +  ++   CIM G++D  L WPF   IT  +I+    +  ++  I   + +P   +   RPI   NVG  C    L  E L    +  +   F+  ++
Sbjct:   24 ELMCGICLMVVNKPVLTYCGHSYCNFCFNKWRNGKDVVTCPVDYKQ---------LETNQFMADKKTERQVLSLCVKCMNGPCSWKGELRDKKKHLTKCDHEVIKCVFDGC--DTRLARNSMEKHEETCEWKIVTCEFCDVPYPKREEETVKHRGDCPLAILPCKFSDIGCTFEGRQHAHVAHCENALQAHLDMACGTIRDNNK-------------EIRKNNKKIRDNNKEIETLHEELNTANQTIRK---------------------LKGQMAKLVGTFVWRI----CDYKDLY----EEIYSPSFYTSKYGYKVQLKAYLHTNPFNGETHLWLYACIMVGEYDALLEWPFRRKITLYVIDQSDQRKHETLLINPDDVLPDRKKCFHRPIMGNNVGY-CLTRSLSLEELTSGGFIADGVMFIKAVV 398
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO45915 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRA4])

HSP 1 Score: 64.3142 bits (155), Expect = 3.844e-11
Identity = 91/422 (21.56%), Postives = 161/422 (38.15%), Query Frame = 3 
Query:   96 FDSEVICVICKTLLQNAYS-GPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNK---DTAINRKISKMIVRCPN--ETCSFSDELVNMDNHM-KVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWN----LQENQNRLC--AQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEE-LRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIK---PNEKNICV--QYLWKFDQINAKLKDTLAGKKKE-FLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIIS 1301
             D    C +C   L++     PCG R C  CI          CP         +  L LN  K   D A +R+I  M + CP+  + C +   + +++ H+ + CNL            ++   +     E    ++ +N     KE     + F   N+       +     L      L   A    +NQ+ P + +P  F         K Q     ++E L ++     D V + K     +++ K   ++  E I+      ++ C   +++WK    + KL D   G+  E  +S+ F TS  GY++   +  N   +G    +   L +  G+FD  L WP     TF L++  +D   K   +  A   P    +RP     +G G     L + +  + + K++  F+   +S
Sbjct:   12 LDKSFECPVCLMALRDPVQVTPCGHRVCQTCIKPIIRNRRPRCP---------LDNLTLNVGKIFPDNACHRQILSMDILCPHHGDGCEWQGTISDLEKHLERGCNLSEVRCPKDCGASVERGKLEGHYPECS--RRLVNCTHCNKE-----VVFADMNVHLQSCASFPISCPLTCGAKDLTKEALAVHLNQECPLLVIPCRFAEAGCTFKAKRQKMAAHVQESLTSHVAMLCDLVCEQK---LQISAQKERLLLQKEHIQLQIVECRSRCANGEFIWKIQCFSRKLMDAKTGRASEPMISEAFYTSPHGYKMCAGVWLNGIGTGRGRYISVGLQVQSGEFDSILKWPLYPRYTFTLLDQSEDTKTKRDVV--ATFEPQ-SISRPSADRQLGKGARRFVLQDEVCGTTYCKDNTIFIKFSVS 411
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: unm_sa808 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101155367])

HSP 1 Score: 65.4698 bits (158), Expect = 5.782e-11
Identity = 39/147 (26.53%), Postives = 67/147 (45.58%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++W+      K +D +AG+     S  F TSK GY++ L++  N   +G    +     +M+G  D  L WPF   +T  L+    D+  +   I  F   V      RP+  MN+  GC L   L ++   + + ++D  F+  I+
Sbjct:  449 FIWRISDFAKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGLSDALLKWPFNQKVTLMLL----DQSNREHIIDAFRPDVTSSSFQRPVSEMNIASGCPLFCPLSKLDAKNSYIRDDTIFIKAIV 591
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 65.4698 bits (158), Expect = 6.078e-11
Identity = 37/147 (25.17%), Postives = 69/147 (46.94%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK    + + ++ ++G+     S  F +SK GY++ L+L  N   +G    +     +M+ K+D  L WPF   +T  L+    D+  +   I  F   +      RP+  MN+  GC L   L ++   S + ++D  F+  I+
Sbjct:  369 FVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLL----DQNNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIV 511
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 65.4698 bits (158), Expect = 6.542e-11
Identity = 37/147 (25.17%), Postives = 69/147 (46.94%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK    + + ++ ++G+     S  F +SK GY++ L+L  N   +G    +     +M+ K+D  L WPF   +T  L+    D+  +   I  F   +      RP+  MN+  GC L   L ++   S + ++D  F+  I+
Sbjct:  376 FVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLL----DQNNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIV 518
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626])

HSP 1 Score: 65.0846 bits (157), Expect = 7.589e-11
Identity = 38/147 (25.85%), Postives = 68/147 (46.26%), Query Frame = 3 
Query:  864 YLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTI-YFANSVPHPGRTRPIGSMNVGLGCFLM-DLDEVLNDSEWKKEDKFFVNCII 1298
            ++WK      K +D +AG+     S  F TSK GY++ L++  N   +G    +     +M+G  D  L WPF   +T  L+    D+  +   I  F   +      RP+  MN+  GC L   L ++ + + + +++  F+  I+
Sbjct:  422 FIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLL----DQNNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIKAIV 564
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601])

HSP 1 Score: 64.3142 bits (155), Expect = 1.295e-10
Identity = 38/151 (25.17%), Postives = 66/151 (43.71%), Query Frame = 3 
Query:  867 LWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSV-PHPGRT---RPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
            +WK      + +D +AGK     S  F T   GY++  ++  N    G    +     +M+G++D  L WPF+  +T  L++      Q     +  ++  P P  +   RP+  MN+  GC L     VL    + K+D  F+   + T+
Sbjct:  301 IWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMD------QGPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQSVLESGTYIKDDTIFIKVTVDTS 445
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000014624.1 (SMESG000014624.1)

HSP 1 Score: 875.544 bits (2261), Expect = 0.000e+0
Identity = 426/426 (100.00%), Postives = 426/426 (100.00%), Query Frame = 3 
Query:   39 MAEFKSIWPSLKCNSSQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTNKKY 1316
            MAEFKSIWPSLKCNSSQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTNKKY
Sbjct:    1 MAEFKSIWPSLKCNSSQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTNKKY 426
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000070267.1 (SMESG000070267.1)

HSP 1 Score: 412.149 bits (1058), Expect = 9.928e-141
Identity = 211/444 (47.52%), Postives = 297/444 (66.89%), Query Frame = 3 
Query:   39 MAEFKSIWPSLKCNSSQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVC-NLGVTL------------------DEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPK-PTEFLLNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCFLMDLDEVLNDSEWKKEDKFFVNCIISTNK 1310
            MA   SIW +LK  SSQ  FD + IC+ICKTLL+NAY GPCGCRYCYECIS Y    + YCPG   ECR++ I LN+NT+KD   NRKISKM+V+CP E+CSF D+L+N++NHMK+C +  VT                    ++V +++   E  N +K EL+ LKQ ++K   EKEF  N  +F+K  IDAN++Q+W+L  NQN++  Q+KEIN+K+ ++   + F       +    NFE+S E L+   +   +  GK     E  L    +E+ VN E   P +K+IC+QYLW+ DQ NAK +   +GK KE  S+TF TS +GY++ LK++F+VYSSGA+ P++ SLC++KGKFD+EL+WPF+YDITFELINP  D+V  SQT+Y+ NSV HPGR +P  +    LGCF++D++++LNDS+W +ED+F++NCI+   K
Sbjct:    1 MALINSIWTTLKHKSSQNDFDPDFICIICKTLLRNAYCGPCGCRYCYECISRYVTRTDKYCPGITEECRAQAISLNINTSKDRLTNRKISKMVVKCPIESCSFKDQLMNIENHMKICCSESVTWFYPGSDNTQLVRQGDHFSQDIVPHSKSLLEFDNDVKEELRALKQNIHKLLIEKEFSRNAFSFYKERIDANKVQMWHLNNNQNQIFIQMKEINEKLLKMTNLMTFE------STAKWNFEESFEHLK---LCPVEADGKSAYNIEKTLMKDADEYFVNIECTPPKKKDICLQYLWEVDQFNAKTRAAFSGKHKEISSETFNTSINGYQMCLKMRFDVYSSGARYPIFLSLCLLKGKFDNELIWPFKYDITFELINPYTDEVYTSQTLYYRNSVIHPGREKPTSNKKFDLGCFMIDVEDILNDSKWDREDRFYINCIVFREK 435
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000020135.1 (SMESG000020135.1)

HSP 1 Score: 165.236 bits (417), Expect = 2.118e-45
Identity = 129/451 (28.60%), Postives = 215/451 (47.67%), Query Frame = 3 
Query:   39 MAEFK--SIWPSLK-CNSSQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCN-------------------LGVTLDEMVNN----TRLQSENINILKVELKELKQTMNKYQTEKEFWTNT---LAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEEL-RNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNI----CVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCF-LMDLDEVLNDSEWKKEDKFFV 1286
            MA+FK  +IW  ++  + S    DS++IC +C  ++ N+++ PCGCR+C +CIS+Y NG E  CPGN  +C+ E+I L  N   D  +N KIS++I++CP  +C + DEL  ++ H+  CN                   LG   D + N+    T+L  + I+ L  E+ E+K  +  ++ + +  TN    LA  ++ +    M+I  L++  + L   +  +++  P++      NI  +N    ++N+   ++ L RN           P     + N + +        +   E N+      +++WK D+ N K+K    GK     SD+F T + GY++ L+L  N  +  A   +   LC+MK   D  L WPF    TF LIN          T  + N        +PI   NVG G    MDL E+ N+ +W + D+ F+
Sbjct:    1 MAKFKFENIWKIMENYDFSGVEVDSDMICGLCGKVMINSHNAPCGCRFCLDCISNYLNGRENLCPGNKDDCKLELISLEENIAIDRPMNNKISRLIIKCPENSCDYVDELRKIELHISQCNSQTIICPYIKIGCNESDVSLGKMPDHLRNDIHNHTKLLMDCIDNLNNEMNEIKIIVGNFKGQFDKNTNDQSYLAEIESKLQQQTMEIDLLKQRVHNL-ENLDFVDR--PKLKAESLNNIISDN----FRNYPNRLDTLNRN--------STNPINLTAVSNKIDDAMKFGLTKLADMEINLKRMKSFEFVWKVDKFNDKMKAAKKGKTLSIFSDSFYTHQYGYKMCLQLFPNGNAEYANNYLSVFLCLMKSDLDDILEWPFRNHFTFSLINQRTRLPHSRSTTTYDNFQMEKCLDKPILERNVGYGYLDFMDLKELFNNDDWTRNDQIFI 436
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000020135.1 (SMESG000020135.1)

HSP 1 Score: 162.155 bits (409), Expect = 1.821e-44
Identity = 123/433 (28.41%), Postives = 204/433 (47.11%), Query Frame = 3 
Query:   84 SQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCN-------------------LGVTLDEMVNN----TRLQSENINILKVELKELKQTMNKYQTEKEFWTNT---LAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQIENMNQKYQNFEKSIEEL-RNYFIKQSDEVGKPKPTEFLLNSLKNEFIVNPEPIKPNEKNI----CVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCF-LMDLDEVLNDSEWKKEDKFFV 1286
            S    DS++IC +C  ++ N+++ PCGCR+C +CIS+Y NG E  CPGN  +C+ E+I L  N   D  +N KIS++I++CP  +C + DEL  ++ H+  CN                   LG   D + N+    T+L  + I+ L  E+ E+K  +  ++ + +  TN    LA  ++ +    M+I  L++  + L   +  +++  P++      NI  +N    ++N+   ++ L RN           P     + N + +        +   E N+      +++WK D+ N K+K    GK     SD+F T + GY++ L+L  N  +  A   +   LC+MK   D  L WPF    TF LIN          T  + N        +PI   NVG G    MDL E+ N+ +W + D+ F+
Sbjct:    7 SGVEVDSDMICGLCGKVMINSHNAPCGCRFCLDCISNYLNGRENLCPGNKDDCKLELISLEENIAIDRPMNNKISRLIIKCPENSCDYVDELRKIELHISQCNSQTIICPYIKIGCNESDVSLGKMPDHLRNDIHNHTKLLMDCIDNLNNEMNEIKIIVGNFKGQFDKNTNDQSYLAEIESKLQQQTMEIDLLKQRVHNL-ENLDFVDR--PKLKAESLNNIISDN----FRNYPNRLDTLNRN--------STNPINLTAVSNKIDDAMKFGLTKLADMEINLKRMKSFEFVWKVDKFNDKMKAAKKGKTLSIFSDSFYTHQYGYKMCLQLFPNGNAEYANNYLSVFLCLMKSDLDDILEWPFRNHFTFSLINQRTRLPHSRSTTTYDNFQMEKCLDKPILERNVGYGYLDFMDLKELFNNDDWTRNDQIFI 424
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000067216.1 (SMESG000067216.1)

HSP 1 Score: 157.532 bits (397), Expect = 1.811e-42
Identity = 117/462 (25.32%), Postives = 217/462 (46.97%), Query Frame = 3 
Query:   48 FKSIWPSLKCNS--SQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECISHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNETCSFSDELVNMDNHMKVCNL-----------------------GVTLDEMVNNTRLQSENINILKVELKELKQTMNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKIPEIGVPVAFNIQ--IENMNQKYQNFEKSIEELRN----YFIKQSDEVGKPKPTEF--LLNSLKNEFIVNPEPIKPN--------EKNICVQYLWKFDQINAKLKDTLAGKKKEFLSDTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEYDITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGC-FLMDLDEVLNDSEWKKEDKFFVNCIISTN 1307
             +S+W ++K  +  S    + E+ C+ICK+++ NA+SGPCGC YC+ECI  Y +    +CPGN  EC+ + + +N +   D + N  +SK++V+CPN+ CSF DEL  ++NH+++CN+                       G  L E+VN+++L  E+I+ L+ E++ LK+T+ K Q EK+  T  +     +    +M    L++  +       E N +I +    V +  +  + N N+        ++   N       K S+EV   +   F    +      +++ + ++          EK    ++LW  +    K      G +  F SD F T K GY++ L++       G    +     +M G+FD+ L WP + DITF++ +         Q+  + +        +P    N+G+G    +++ E+ ++     ++K F+ C ++ N
Sbjct:    1 MESLWETMKKMAFVSCQPVNHELTCLICKSIVINAHSGPCGCLYCFECIVTYLSKGIRFCPGNTEECQVKTLNINEDIVVDRSSNVSVSKLVVKCPNKNCSFKDELRQIENHLRICNMKCEKCPYFEIGCKESEISTEELSGHILQEIVNHSKLLLESIDNLRNEVESLKRTVEKLQVEKKQLTEEVELVMIDKIVKEMVREQLKQAMDEKVGGFNE-NTQISKKEDFVLYKCEKKLINANETSNEAANRVKGKSNSEQPMKDKSSNEVTGAQCEGFSKFTDKSNKSLVIDVQNLQSQILKIESNLEKENYGEFLWILENWWEKFHQAKLGIQSSFFSDAFFTHKYGYKLCLRIYPVGIGEGKGSHLSVFFHVMSGQFDNTLPWPCKLDITFKMSDQESGYDHVVQSCSYESKPNSSSYRKPTSDKNIGIGIPKFIEIKELFSNINLSSDNKLFIRCSVNIN 461
The following BLAST results are available for this feature:
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRAF16.572e-1221.70TNF receptor associated factor 1 [Source:HGNC Symb... [more]
TRAF11.207e-1127.81TNF receptor associated factor 1 [Source:HGNC Symb... [more]
TRAF11.207e-1127.81TNF receptor associated factor 1 [Source:HGNC Symb... [more]
TRAF31.529e-1020.45TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF31.529e-1020.45TNF receptor associated factor 3 [Source:HGNC Symb... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor associated factor-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Traf41.173e-629.13gene:FBgn0026319 transcript:FBtr0077429[more]
Traf41.777e-629.13gene:FBgn0026319 transcript:FBtr0334401[more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf2b5.640e-1429.25Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
traf2b5.640e-1429.25Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
traf2b5.896e-1429.25Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
BX901915.15.465e-1226.53pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:2... [more]
AL844899.15.465e-1226.53pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hspb64.552e-1531.58heat shock protein family B (small) member 6 [Sour... [more]
TRAF21.775e-1027.21TNF receptor associated factor 2 [Source:NCBI gene... [more]
TRAF24.886e-1027.21TNF receptor associated factor 2 [Source:NCBI gene... [more]
ssh21.162e-918.04slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
ssh22.120e-923.84slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Traf19.126e-1329.14TNF receptor-associated factor 1 [Source:MGI Symbo... [more]
Traf19.126e-1329.14TNF receptor-associated factor 1 [Source:MGI Symbo... [more]
Traf19.126e-1329.14TNF receptor-associated factor 1 [Source:MGI Symbo... [more]
Traf37.782e-1120.15TNF receptor-associated factor 3 [Source:MGI Symbo... [more]
Traf37.782e-1120.15TNF receptor-associated factor 3 [Source:MGI Symbo... [more]
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BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3ZCC3|TRAF6_BOVIN3.065e-1421.94TNF receptor-associated factor 6 OS=Bos taurus OX=... [more]
sp|P39428|TRAF1_MOUSE6.384e-1229.14TNF receptor-associated factor 1 OS=Mus musculus O... [more]
sp|Q13077|TRAF1_HUMAN5.798e-1127.81TNF receptor-associated factor 1 OS=Homo sapiens O... [more]
sp|Q60803|TRAF3_MOUSE1.544e-926.14TNF receptor-associated factor 3 OS=Mus musculus O... [more]
sp|Q13114|TRAF3_HUMAN1.559e-926.14TNF receptor-associated factor 3 OS=Homo sapiens O... [more]
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BLAST of TNF receptor associated factor-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I1ZID85.914e-1843.62TNF receptor associated factor-2 (Fragment) OS=Sch... [more]
A0A093FV747.520e-1822.66TNF receptor-associated factor 2 (Fragment) OS=Gav... [more]
A0A1S3K6C14.819e-1722.52TNF receptor-associated factor 2 OS=Lingula unguis... [more]
T0MIZ11.845e-1623.53TNF receptor-associated factor OS=Camelus ferus OX... [more]
T1E1012.077e-1622.92TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf2b1.037e-1328.57TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf18.314e-1330.00TNF receptor-associated factor 1-like [Source:NCBI... [more]
traf19.168e-1330.00TNF receptor-associated factor 1-like [Source:NCBI... [more]
traf2a1.145e-1126.53TNF receptor-associated factor 2-like [Source:NCBI... [more]
traf2a1.701e-1126.53TNF receptor-associated factor 2-like [Source:NCBI... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000000074.13.022e-1125.49pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-... [more]
ENSPMAT00000002130.18.375e-1122.75pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 g... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO483949.648e-2023.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495455.592e-1322.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328513.614e-1128.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO316923.709e-1121.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459153.844e-1121.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unm_sa8085.782e-1126.53TNF receptor-associated factor 2 [Source:NCBI gene... [more]
traf2b6.078e-1125.17TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf2b6.542e-1125.17TNF receptor associated factor 2 [Source:NCBI gene... [more]
ENSORLT00000020861.27.589e-1125.85TNF receptor-associated factor 2 [Source:NCBI gene... [more]
traf31.295e-1025.17TNF receptor associated factor 3 [Source:NCBI gene... [more]
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BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000014624.10.000e+0100.00SMESG000014624.1[more]
SMESG000070267.19.928e-14147.52SMESG000070267.1[more]
SMESG000020135.12.118e-4528.60SMESG000020135.1[more]
SMESG000020135.11.821e-4428.41SMESG000020135.1[more]
SMESG000067216.11.811e-4225.32SMESG000067216.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029882 ID=SMED30029882|Name=TNF receptor associated factor-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1500bp
ATTGACATTCATTTATCAGAGAAAGTGATTTTTCGAAAATGGCAGAATTC
AAAAGCATCTGGCCAAGTTTGAAATGCAATTCCTCACAATACAGATTTGA
CTCCGAAGTGATCTGTGTGATTTGCAAAACACTTCTACAAAACGCCTATT
CTGGACCTTGCGGATGCCGATATTGCTACGAATGTATTTCTCATTACTCG
AATGGACCGGAAATTTATTGCCCGGGAAATCTCCCCGAATGTCGGAGTGA
AATCATAATCTTGAACTTAAACACTAATAAGGATACAGCAATCAACCGAA
AGATATCAAAAATGATAGTCAGATGCCCAAACGAAACTTGCTCTTTTTCT
GACGAATTGGTGAATATGGATAACCACATGAAAGTCTGCAACCTAGGAGT
AACTTTGGACGAAATGGTCAATAATACAAGATTACAATCAGAAAACATTA
ACATTCTGAAAGTCGAACTCAAAGAATTAAAACAAACGATGAATAAATAC
CAGACAGAAAAGGAGTTTTGGACAAATACACTCGCATTTTTCAAAGCGAA
CATTGATGCCAATCAGATGCAGATTTGGAATTTACAGGAGAATCAAAACC
GACTTTGCGCTCAAATAAAAGAAATTAATCAGAAAATACCTGAAATAGGG
GTCCCAGTGGCTTTTAACATACAAATAGAAAACATGAATCAAAAATATCA
AAATTTTGAAAAATCAATAGAAGAATTGCGAAATTATTTCATCAAACAGT
CTGATGAAGTTGGTAAACCCAAACCTACAGAATTTCTCTTGAATTCTCTT
AAAAATGAATTTATTGTAAACCCTGAACCTATAAAACCAAACGAAAAAAA
CATTTGCGTCCAATATTTGTGGAAATTTGATCAAATTAATGCCAAGCTAA
AAGATACCTTGGCTGGTAAAAAAAAAGAATTTCTCAGTGATACGTTTCAA
ACTAGTAAAGACGGCTACGAAATTCGCTTGAAATTGCAATTCAATGTCTA
CTCAAGCGGGGCCAAATTACCAGTATACCAGTCTTTATGTATAATGAAAG
GCAAATTCGACCATGAATTATTGTGGCCATTTGAATACGACATAACGTTC
GAACTCATCAATCCGTGCAAAGATAAAGTTCAAAAGAGTCAAACGATTTA
TTTTGCCAATTCAGTCCCTCACCCCGGACGAACCAGGCCGATCGGTAGCA
TGAATGTTGGACTCGGATGTTTTCTTATGGATCTCGATGAAGTACTTAAT
GATTCCGAATGGAAGAAAGAAGATAAATTCTTTGTTAACTGCATAATTTC
CACTAACAAAAAATATTAATAATATGCACTCACCTAATTTTTTGATGATT
TCTGAAATATTTTTTTATTACAACTGACAATGGAAAATTACGGATGATTG
GTATTTTGCAAAGGGACACTTGACCCAGTCAATGTGAAATTACAGTTATT
TATTTAAAAATTTTTTTTTCATAATGCATTCAAGTTTGTTTTATCTATCG
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protein sequence of SMED30029882-orf-1

>SMED30029882-orf-1 ID=SMED30029882-orf-1|Name=SMED30029882-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=427bp
MAEFKSIWPSLKCNSSQYRFDSEVICVICKTLLQNAYSGPCGCRYCYECI
SHYSNGPEIYCPGNLPECRSEIIILNLNTNKDTAINRKISKMIVRCPNET
CSFSDELVNMDNHMKVCNLGVTLDEMVNNTRLQSENINILKVELKELKQT
MNKYQTEKEFWTNTLAFFKANIDANQMQIWNLQENQNRLCAQIKEINQKI
PEIGVPVAFNIQIENMNQKYQNFEKSIEELRNYFIKQSDEVGKPKPTEFL
LNSLKNEFIVNPEPIKPNEKNICVQYLWKFDQINAKLKDTLAGKKKEFLS
DTFQTSKDGYEIRLKLQFNVYSSGAKLPVYQSLCIMKGKFDHELLWPFEY
DITFELINPCKDKVQKSQTIYFANSVPHPGRTRPIGSMNVGLGCFLMDLD
EVLNDSEWKKEDKFFVNCIISTNKKY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000208testis
PLANA:0002056medial muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR043211TNF_rcpt-assoc_TRAF
IPR008974TRAF-like
IPR013083Znf_RING/FYVE/PHD
IPR001841Znf_RING
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0004842ubiquitin-protein transferase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006955immune response
GO:0007165signal transduction
GO:0016567protein ubiquitination
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 137..164
NoneNo IPR availableCOILSCoilCoilcoord: 213..233
NoneNo IPR availableCOILSCoilCoilcoord: 179..199
NoneNo IPR availablePANTHERPTHR10131:SF129TNF RECEPTOR-ASSOCIATED FACTOR 6coord: 20..421
NoneNo IPR availableCDDcd16449RING-HCcoord: 26..62
e-value: 2.28728E-6
score: 42.0693
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 20..78
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 9..127
e-value: 2.1E-14
score: 55.6
IPR008974TRAF-likeGENE3DG3DSA:2.60.210.10coord: 263..425
e-value: 9.4E-25
score: 89.1
IPR008974TRAF-likeSUPERFAMILYSSF49599TRAF domain-likecoord: 275..422
IPR043211TNF receptor-associated factor TRAFPANTHERPTHR10131TNF RECEPTOR ASSOCIATED FACTORcoord: 20..421
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 26..62
score: 8.963