SMED30029873

Overview


Name	SMED30029873
Smed ID	SMED30029873
Length (bp)	1415

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30029873 (SMED30029873) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30029873 (SMED30029873) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30029873 (SMED30029873) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30029873 (SMED30029873) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30029873

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 17

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Category 2 cell	SMED30029873	h1SMcG0015702	SMED30029873	smed_20140614	PMID:29100657 Cheng et al., 2018
Category 3 cell	SMED30029873	h1SMcG0015702	SMED30029873	smed_20140614	PMID:29100657 Cheng et al., 2018
X1 cell	SMED30029873	h1SMcG0015702	SMED30029873	smed_20140614	PMID:29100657 Cheng et al., 2018
Smed sexual biotype	SMED30029873	h1SMcG0015702	Contig51323	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30029873	h1SMcG0015702	Contig51323	newmark_ests	PMID:29674431 Fincher et al., 2018
epidermis	SMED30029873	h1SMcG0015702	dd_Smed_v4_5474_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30029873	h1SMcG0015702	dd_Smed_v4_5474_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30029873	h1SMcG0015702	dd_Smed_v4_7038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30029873	h1SMcG0015702	dd_Smed_v4_7038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30029873	h1SMcG0015702	SMED30029873	smed_20140614	PMID:26457503 Tu et al., 2015
parenchyma	SMED30029873	h1SMcG0015702	SMED30029873	smed_20140614	PMID:26457503 Tu et al., 2015
Category 3 cell	SMED30029873	h1SMcG0015702	dd_Smed_v6_5474_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 3 cell	SMED30029873	h1SMcG0015702	dd_Smed_v6_7038_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30029873	h1SMcG0015702	dd_Smed_v4_5474_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
Category 3 cell	SMED30029873	h1SMcG0015702	dd_Smed_v4_5474_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
epidermis	SMED30029873	h1SMcG0015702	dd_Smed_v4_7038_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
Category 3 cell	SMED30029873	h1SMcG0015702	dd_Smed_v4_7038_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Alignments

SMED30029873 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.000696:109881..111348 +	7016

Homology

[Close]

BLAST of SMED30029873 vs. Ensembl Human
Match: EGR1 (early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238])

HSP 1 Score: 117.087 bits (292), Expect = 1.625e-27
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:  344 SCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 419

HSP 2 Score: 57.3806 bits (137), Expect = 3.362e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  368 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 422

[Close]

BLAST of SMED30029873 vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 109.383 bits (272), Expect = 1.639e-25
Identity = 45/75 (60.00%), Postives = 55/75 (73.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+AC+ C ++FARSDE+ RH K H 
Sbjct:  282 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHL 356

HSP 2 Score: 58.9214 bits (141), Expect = 9.543e-9
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H  +K
Sbjct:  305 FQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359

[Close]

BLAST of SMED30029873 vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 107.842 bits (268), Expect = 2.560e-25
Identity = 45/75 (60.00%), Postives = 55/75 (73.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+AC+ C ++FARSDE+ RH K H 
Sbjct:  244 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHL 318

HSP 2 Score: 57.7658 bits (138), Expect = 1.979e-8
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H  +K
Sbjct:  267 FQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 321

[Close]

BLAST of SMED30029873 vs. Ensembl Human
Match: EGR2 (early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239])

HSP 1 Score: 109.383 bits (272), Expect = 4.236e-25
Identity = 47/75 (62.67%), Postives = 56/75 (74.67%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+ACD C ++FARSDE+ RHTK H 
Sbjct:  347 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHL 421

HSP 2 Score: 62.7734 bits (151), Expect = 6.102e-10
Identity = 30/64 (46.88%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  930 RHEKIHSGEKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            R  K    E+P  CP   CD+ F RSD    HIR HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  329 RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 392

HSP 3 Score: 57.3806 bits (137), Expect = 3.166e-8
Identity = 25/55 (45.45%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C YC + F RSD RK H + H  +K
Sbjct:  370 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQK 424

[Close]

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+ACD C ++FARSDE+ RHTK H 
Sbjct:  347 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHL 421

HSP 2 Score: 62.7734 bits (151), Expect = 6.102e-10
Identity = 30/64 (46.88%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  930 RHEKIHSGEKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            R  K    E+P  CP   CD+ F RSD    HIR HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  329 RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 392

HSP 3 Score: 57.3806 bits (137), Expect = 3.166e-8
Identity = 25/55 (45.45%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C YC + F RSD RK H + H  +K
Sbjct:  370 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQK 424

[Close]

BLAST of SMED30029873 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 112.079 bits (279), Expect = 1.036e-27
Identity = 48/74 (64.86%), Postives = 57/74 (77.03%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            CD KF+R DEL RH +IH+G+KP  C  C + F RSDH  TH+RTHTGEKPY+CDIC K+FAR DE+ RHTK H
Sbjct:  185 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 258

HSP 2 Score: 52.7582 bits (125), Expect = 2.030e-7
Identity = 23/51 (45.10%), Postives = 28/51 (54.90%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C  +F+R D L  H + H+GEKP SC  C K F R D R  H + H
Sbjct:  208 FQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 258

[Close]

BLAST of SMED30029873 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 106.301 bits (264), Expect = 2.031e-27
Identity = 48/74 (64.86%), Postives = 57/74 (77.03%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            CD KF+R DEL RH +IH+G+KP  C  C + F RSDH  TH+RTHTGEKPY+CDIC K+FAR DE+ RHTK H
Sbjct:   20 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 93

HSP 2 Score: 46.9802 bits (110), Expect = 1.794e-6
Identity = 23/51 (45.10%), Postives = 28/51 (54.90%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C  +F+R D L  H + H+GEKP SC  C K F R D R  H + H
Sbjct:   43 FQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 93

[Close]

BLAST of SMED30029873 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 111.694 bits (278), Expect = 2.144e-27
Identity = 48/74 (64.86%), Postives = 57/74 (77.03%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            CD KF+R DEL RH +IH+G+KP  C  C + F RSDH  TH+RTHTGEKPY+CDIC K+FAR DE+ RHTK H
Sbjct:  185 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 258

HSP 2 Score: 53.5286 bits (127), Expect = 1.154e-7
Identity = 24/56 (42.86%), Postives = 29/56 (51.79%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKP 1046
            F C  C  +F+R D L  H + H+GEKP SC  C K F R D R  H + H    P
Sbjct:  208 FQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGP 263

[Close]

BLAST of SMED30029873 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 105.531 bits (262), Expect = 5.313e-27
Identity = 48/74 (64.86%), Postives = 57/74 (77.03%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            CD KF+R DEL RH +IH+G+KP  C  C + F RSDH  TH+RTHTGEKPY+CDIC K+FAR DE+ RHTK H
Sbjct:   20 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 93

HSP 2 Score: 48.521 bits (114), Expect = 8.329e-7
Identity = 24/56 (42.86%), Postives = 29/56 (51.79%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKP 1046
            F C  C  +F+R D L  H + H+GEKP SC  C K F R D R  H + H    P
Sbjct:   43 FQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGP 98

[Close]

BLAST of SMED30029873 vs. Ensembl Celegans
Match: egrh-1 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:Q18250])

HSP 1 Score: 113.235 bits (282), Expect = 6.349e-27
Identity = 46/74 (62.16%), Postives = 58/74 (78.38%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  TH+RTHTGEKP++CDIC ++FARSDE+ RHTK H
Sbjct:  381 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRAFSRSDHLTTHVRTHTGEKPFSCDICGRKFARSDERKRHTKVH 454

HSP 2 Score: 56.9954 bits (136), Expect = 1.669e-8
Identity = 24/51 (47.06%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD RK H + H
Sbjct:  404 FQCRICMRAFSRSDHLTTHVRTHTGEKPFSCDICGRKFARSDERKRHTKVH 454

[Close]

BLAST of SMED30029873 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0330050)

HSP 1 Score: 116.701 bits (291), Expect = 2.162e-27
Identity = 47/75 (62.67%), Postives = 57/75 (76.00%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP++CDIC ++FARSDEK RH K H 
Sbjct: 1043 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHL 1117

HSP 2 Score: 57.7658 bits (138), Expect = 1.904e-8
Identity = 23/55 (41.82%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD +K H + H  ++
Sbjct: 1066 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQR 1120

[Close]

BLAST of SMED30029873 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0083542)

HSP 1 Score: 116.701 bits (291), Expect = 2.200e-27
Identity = 47/75 (62.67%), Postives = 57/75 (76.00%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP++CDIC ++FARSDEK RH K H 
Sbjct: 1043 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHL 1117

HSP 2 Score: 57.3806 bits (137), Expect = 2.173e-8
Identity = 23/55 (41.82%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD +K H + H  ++
Sbjct: 1066 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQR 1120

[Close]

BLAST of SMED30029873 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0301615)

HSP 1 Score: 115.161 bits (287), Expect = 4.920e-27
Identity = 47/75 (62.67%), Postives = 57/75 (76.00%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP++CDIC ++FARSDEK RH K H 
Sbjct:  574 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHL 648

HSP 2 Score: 56.225 bits (134), Expect = 4.178e-8
Identity = 23/55 (41.82%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD +K H + H  ++
Sbjct:  597 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQR 651

[Close]

BLAST of SMED30029873 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0344633)

HSP 1 Score: 115.161 bits (287), Expect = 6.608e-27
Identity = 47/75 (62.67%), Postives = 57/75 (76.00%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP++CDIC ++FARSDEK RH K H 
Sbjct:  763 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHL 837

HSP 2 Score: 56.225 bits (134), Expect = 4.945e-8
Identity = 23/51 (45.10%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD +K H + H
Sbjct:  786 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVH 836

[Close]

BLAST of SMED30029873 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0083543)

HSP 1 Score: 115.161 bits (287), Expect = 6.608e-27
Identity = 47/75 (62.67%), Postives = 57/75 (76.00%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP++CDIC ++FARSDEK RH K H 
Sbjct:  763 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHL 837

HSP 2 Score: 56.225 bits (134), Expect = 4.945e-8
Identity = 23/51 (45.10%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD +K H + H
Sbjct:  786 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVH 836

[Close]

BLAST of SMED30029873 vs. Ensembl Zebrafish
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:30498])

HSP 1 Score: 115.931 bits (289), Expect = 1.901e-27
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            TCD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+AC+IC ++FARSDE+ RHTK H 
Sbjct:  317 TCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHM 392

HSP 2 Score: 57.7658 bits (138), Expect = 1.800e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  341 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQK 395

[Close]

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            TCD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+AC+IC ++FARSDE+ RHTK H 
Sbjct:  317 TCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHM 392

HSP 2 Score: 57.7658 bits (138), Expect = 1.800e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  341 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQK 395

[Close]

BLAST of SMED30029873 vs. Ensembl Zebrafish
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 111.694 bits (278), Expect = 8.841e-27
Identity = 44/76 (57.89%), Postives = 58/76 (76.32%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +C+ +F+R DEL RH +IH+G KP  C  C +CF RSDH  TH+RTHTGEKP++CD+C +RFARSDE+ RH + H 
Sbjct:  256 SCERRFSRSDELNRHVRIHTGHKPFQCRVCLRCFSRSDHLTTHMRTHTGEKPFSCDVCARRFARSDERKRHMRVHL 331

HSP 2 Score: 56.225 bits (134), Expect = 3.497e-8
Identity = 25/55 (45.45%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD RK H+R H  ++
Sbjct:  280 FQCRVCLRCFSRSDHLTTHMRTHTGEKPFSCDVCARRFARSDERKRHMRVHLKQR 334

[Close]

BLAST of SMED30029873 vs. Ensembl Zebrafish
Match: egr2b (early growth response 2b [Source:NCBI gene;Acc:30190])

HSP 1 Score: 110.153 bits (274), Expect = 7.993e-26
Identity = 47/75 (62.67%), Postives = 56/75 (74.67%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+ACD C ++FARSDE+ RHTK H 
Sbjct:  306 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHL 380

HSP 2 Score: 63.1586 bits (152), Expect = 2.643e-10
Identity = 30/64 (46.88%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  930 RHEKIHSGEKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            R  K    E+P  CP   CD+ F RSD    HIR HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  288 RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 351

HSP 3 Score: 56.9954 bits (136), Expect = 2.645e-8
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H  +K
Sbjct:  329 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQK 383

[Close]

BLAST of SMED30029873 vs. Ensembl Zebrafish
Match: egr2a (early growth response 2a [Source:ZFIN;Acc:ZDB-GENE-030723-6])

HSP 1 Score: 106.301 bits (264), Expect = 9.057e-26
Identity = 46/74 (62.16%), Postives = 56/74 (75.68%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP++CD C ++FARSDE+ RHTK H
Sbjct:  155 CDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIH 228

HSP 2 Score: 60.077 bits (144), Expect = 8.276e-10
Identity = 27/56 (48.21%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            E+P  CP   CD+ F RSD    H+R HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  145 ERPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTH 200

HSP 3 Score: 53.5286 bits (127), Expect = 1.521e-7
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC +C + F RSD R+ H + H   K
Sbjct:  178 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHK 232

[Close]

BLAST of SMED30029873 vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 117.472 bits (293), Expect = 7.190e-28
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:  313 SCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 388

HSP 2 Score: 58.151 bits (139), Expect = 1.918e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  337 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 391

[Close]

BLAST of SMED30029873 vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 117.087 bits (292), Expect = 8.391e-28
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:  286 SCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 361

HSP 2 Score: 57.7658 bits (138), Expect = 2.264e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  310 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 364

[Close]

BLAST of SMED30029873 vs. Ensembl Xenopus
Match: serpinb4 (serpin peptidase inhibitor, clade B (ovalbumin), member 4 [Source:Xenbase;Acc:XB-GENE-5787878])

HSP 1 Score: 110.923 bits (276), Expect = 3.822e-26
Identity = 46/75 (61.33%), Postives = 55/75 (73.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+ACD C ++FARSDE+ RH K H 
Sbjct:  279 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHAKIHL 353

HSP 2 Score: 57.3806 bits (137), Expect = 2.577e-8
Identity = 23/51 (45.10%), Postives = 30/51 (58.82%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H
Sbjct:  302 FQCRICMRSFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHAKIH 352

[Close]

BLAST of SMED30029873 vs. Ensembl Xenopus
Match: tbl1x (transducin beta like 1 X-linked [Source:Xenbase;Acc:XB-GENE-982285])

HSP 1 Score: 108.997 bits (271), Expect = 1.826e-25
Identity = 47/75 (62.67%), Postives = 56/75 (74.67%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+ACD C ++FARSDE+ RHTK H 
Sbjct:  268 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHL 342

HSP 2 Score: 62.7734 bits (151), Expect = 4.879e-10
Identity = 30/64 (46.88%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  930 RHEKIHSGEKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            R  K    E+P  CP   CD+ F RSD    HIR HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  250 RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 313

HSP 3 Score: 57.7658 bits (138), Expect = 1.914e-8
Identity = 25/55 (45.45%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C YC + F RSD RK H + H  +K
Sbjct:  291 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQK 345

[Close]

BLAST of SMED30029873 vs. Ensembl Xenopus
Match: usp31 (ubiquitin specific peptidase 31 [Source:Xenbase;Acc:XB-GENE-920956])

HSP 1 Score: 106.686 bits (265), Expect = 3.903e-24
Identity = 48/82 (58.54%), Postives = 56/82 (68.29%), Query Frame = 3

Query:  879 FCC--STCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            F C   +C   F R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP++CD+C +RFARSDEK RH K H 
Sbjct:  440 FACPVESCIRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDLCGRRFARSDEKKRHGKVHM 521

HSP 2 Score: 58.151 bits (139), Expect = 1.717e-8
Identity = 29/74 (39.19%), Postives = 40/74 (54.05%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLR 1100
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD +K H + H           +K+ AR++EKL+
Sbjct:  470 FQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDLCGRRFARSDEKKRHGKVH-----------MKQKARTEEKLK 532

[Close]

BLAST of SMED30029873 vs. Ensembl Mouse
Match: Egr1 (early growth response 1 [Source:MGI Symbol;Acc:MGI:95295])

HSP 1 Score: 117.087 bits (292), Expect = 1.026e-27
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:  342 SCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 417

HSP 2 Score: 57.3806 bits (137), Expect = 2.280e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  366 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 420

[Close]

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:  342 SCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 417

HSP 2 Score: 57.3806 bits (137), Expect = 2.280e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  366 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 420

[Close]

BLAST of SMED30029873 vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 109.383 bits (272), Expect = 1.073e-25
Identity = 45/75 (60.00%), Postives = 55/75 (73.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+AC+ C ++FARSDE+ RH K H 
Sbjct:  282 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHL 356

HSP 2 Score: 58.9214 bits (141), Expect = 6.610e-9
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H  +K
Sbjct:  305 FQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359

[Close]

BLAST of SMED30029873 vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 108.227 bits (269), Expect = 1.707e-25
Identity = 45/75 (60.00%), Postives = 55/75 (73.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+AC+ C ++FARSDE+ RH K H 
Sbjct:  244 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHL 318

HSP 2 Score: 57.7658 bits (138), Expect = 1.311e-8
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H  +K
Sbjct:  267 FQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 321

[Close]

BLAST of SMED30029873 vs. Ensembl Mouse
Match: Egr4 (early growth response 4 [Source:MGI Symbol;Acc:MGI:99252])

HSP 1 Score: 109.768 bits (273), Expect = 1.744e-25
Identity = 48/82 (58.54%), Postives = 57/82 (69.51%), Query Frame = 3

Query:  879 FCCS--TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            F C   +C   F R DEL RH +IH+G KP  C  C + F RSDH  TH+RTHTGEKP+ACD+C +RFARSDEK RH+K H 
Sbjct:  372 FACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHL 453

HSP 2 Score: 57.3806 bits (137), Expect = 2.381e-8
Identity = 28/74 (37.84%), Postives = 40/74 (54.05%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLR 1100
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD +K H + H           LK+ AR++E+L+
Sbjct:  402 FQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVH-----------LKQKARAEERLK 464

[Close]

BLAST of SMED30029873 vs. UniProt/SwissProt
Match: sp|O73693|EGR1_TAEGU (Early growth response protein 1 (Fragment) OS=Taeniopygia guttata OX=59729 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 9.732e-28
Identity = 48/75 (64.00%), Postives = 58/75 (77.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 75

HSP 2 Score: 54.299 bits (129), Expect = 3.479e-7
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:   24 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78

[Close]

BLAST of SMED30029873 vs. UniProt/SwissProt
Match: sp|O73692|EGR1_COTJA (Early growth response protein 1 (Fragment) OS=Coturnix japonica OX=93934 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 1.451e-27
Identity = 48/75 (64.00%), Postives = 58/75 (77.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 75

HSP 2 Score: 53.9138 bits (128), Expect = 4.820e-7
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:   24 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78

[Close]

BLAST of SMED30029873 vs. UniProt/SwissProt
Match: sp|O73691|EGR1_CHICK (Early growth response protein 1 (Fragment) OS=Gallus gallus OX=9031 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 3.283e-27
Identity = 48/75 (64.00%), Postives = 58/75 (77.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 75

HSP 2 Score: 53.1434 bits (126), Expect = 8.566e-7
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:   24 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78

[Close]

BLAST of SMED30029873 vs. UniProt/SwissProt
Match: sp|A4II20|EGR1_XENTR (Early growth response protein 1 OS=Xenopus tropicalis OX=8364 GN=egr1 PE=2 SV=2)

HSP 1 Score: 117.472 bits (293), Expect = 3.809e-27
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:  313 SCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 388

HSP 2 Score: 58.151 bits (139), Expect = 1.016e-7
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  337 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 391

[Close]

BLAST of SMED30029873 vs. UniProt/SwissProt
Match: sp|Q6GQH4|EGR1A_XENLA (Early growth response protein 1-A OS=Xenopus laevis OX=8355 GN=egr1-a PE=2 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 6.744e-27
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+ACDIC ++FARSDE+ RHTK H 
Sbjct:  312 SCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHL 387

HSP 2 Score: 57.7658 bits (138), Expect = 1.147e-7
Identity = 25/60 (41.67%), Postives = 32/60 (53.33%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACD 1058
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K    D
Sbjct:  336 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKAD 395

[Close]

BLAST of SMED30029873 vs. TrEMBL
Match: I1ZI72 (Early growth response-4 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 4.983e-38
Identity = 65/80 (81.25%), Postives = 70/80 (87.50%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            F C  C  KF+RRDEL+RHEKIHSGEKPLSCPYCDKCF+RSDHR THIRTHTGEKPY+CDIC KRFARSDEKLRH + H 
Sbjct:  199 FPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHL 278

[Close]

BLAST of SMED30029873 vs. TrEMBL
Match: H9CXV3 (EGR-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 4.294e-32
Identity = 59/79 (74.68%), Postives = 67/79 (84.81%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            F CS C  +FTR+DELRRHEKIH+G K L CPYCDK FIRSDHR+THIRTHTGEKPY+C+IC K FARSDE+ RHT+ H
Sbjct:  182 FTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 260

[Close]

BLAST of SMED30029873 vs. TrEMBL
Match: T1DF98 (Egrl-3 (Fragment) OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 1.343e-27
Identity = 52/77 (67.53%), Postives = 61/77 (79.22%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTK 1109
            F CSTC   F+RRDEL+RHE+IHSGE+PLSC YC+K F+RSDHR TH+R HTGEKPY C  C   F RSDE+LRH +
Sbjct:  108 FPCSTCTKSFSRRDELKRHERIHSGERPLSCDYCNKRFMRSDHRATHLRIHTGEKPYHCHFCPISFGRSDERLRHMR 184

[Close]

BLAST of SMED30029873 vs. TrEMBL
Match: T1E116 (Egrl-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 8.417e-27
Identity = 51/78 (65.38%), Postives = 58/78 (74.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKT 1112
            F CSTC   F RRDELRRH +IHSGE+PL+C +CDK F+RSDHR TH R HTGEKPY C  C   F RSDE+LRH + 
Sbjct:   96 FICSTCMKPFFRRDELRRHGRIHSGERPLACDFCDKRFMRSDHRTTHRRIHTGEKPYKCHFCASSFGRSDERLRHMRV 173

[Close]

BLAST of SMED30029873 vs. TrEMBL
Match: G1CSV5 (EGR-like protein 1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 2.291e-26
Identity = 50/81 (61.73%), Postives = 63/81 (77.78%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTK-THF 1118
            F C+TC   F RRDEL+RHE+IH+GE+PL+C +CDK F+RSDH  TH+R HTGEKPY C  C + F+RSDE+LRH + TH 
Sbjct:  106 FTCNTCKKSFYRRDELKRHERIHTGERPLACHFCDKRFMRSDHLSTHVRIHTGEKPYQCSYCDRLFSRSDERLRHIRQTHL 186

[Close]

BLAST of SMED30029873 vs. Ensembl Cavefish
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:103036296])

HSP 1 Score: 115.161 bits (287), Expect = 3.211e-27
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            TCD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+AC+IC ++FARSDE+ RHTK H 
Sbjct:  324 TCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHL 399

HSP 2 Score: 55.4546 bits (132), Expect = 6.796e-8
Identity = 23/51 (45.10%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H
Sbjct:  348 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIH 398

[Close]

BLAST of SMED30029873 vs. Ensembl Cavefish
Match: EGR2 (early growth response protein 2b-like [Source:NCBI gene;Acc:103032442])

HSP 1 Score: 109.768 bits (273), Expect = 6.334e-26
Identity = 45/74 (60.81%), Postives = 56/74 (75.68%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            CD +F+R DEL RH ++H+G KP  C  C + F RSDH  THIRTHTGEKP+ACD+C ++FARSDE+ RH K H
Sbjct:  284 CDRRFSRSDELARHVRVHTGHKPFQCRICMRSFGRSDHLTTHIRTHTGEKPFACDLCGRKFARSDERRRHAKIH 357

HSP 2 Score: 62.7734 bits (151), Expect = 2.870e-10
Identity = 27/56 (48.21%), Postives = 34/56 (60.71%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            E+P  CP   CD+ F RSD    H+R HTG KP+ C IC++ F RSD    H +TH
Sbjct:  274 ERPYPCPAEGCDRRFSRSDELARHVRVHTGHKPFQCRICMRSFGRSDHLTTHIRTH 329

HSP 3 Score: 51.9878 bits (123), Expect = 7.327e-7
Identity = 22/51 (43.14%), Postives = 28/51 (54.90%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F R D L  H + H+GEKP +C  C + F RSD R+ H + H
Sbjct:  307 FQCRICMRSFGRSDHLTTHIRTHTGEKPFACDLCGRKFARSDERRRHAKIH 357

[Close]

BLAST of SMED30029873 vs. Ensembl Cavefish
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:103046494])

HSP 1 Score: 109.768 bits (273), Expect = 7.844e-26
Identity = 47/75 (62.67%), Postives = 56/75 (74.67%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+ACD C ++FARSDE+ RHTK H 
Sbjct:  303 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHL 377

HSP 2 Score: 62.7734 bits (151), Expect = 3.193e-10
Identity = 30/64 (46.88%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  930 RHEKIHSGEKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            R  K    E+P  CP   CD+ F RSD    HIR HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  285 RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 348

HSP 3 Score: 56.6102 bits (135), Expect = 2.899e-8
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H  +K
Sbjct:  326 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQK 380

[Close]

BLAST of SMED30029873 vs. Ensembl Cavefish
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:103035480])

HSP 1 Score: 107.842 bits (268), Expect = 4.052e-25
Identity = 44/75 (58.67%), Postives = 55/75 (73.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP++C+ C ++FARSDE+ RH K H 
Sbjct:  309 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHL 383

HSP 2 Score: 62.7734 bits (151), Expect = 2.799e-10
Identity = 27/56 (48.21%), Postives = 36/56 (64.29%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            E+P +CP   CD+ F RSD    H+R HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  299 ERPHACPAENCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTH 354

HSP 3 Score: 59.3066 bits (142), Expect = 4.157e-9
Identity = 25/55 (45.45%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC +C + F RSD RK H + H  +K
Sbjct:  332 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 386

[Close]

BLAST of SMED30029873 vs. Ensembl Cavefish
Match: egr4 (early growth response protein 1-B [Source:NCBI gene;Acc:103025429])

HSP 1 Score: 104.375 bits (259), Expect = 2.226e-24
Identity = 41/75 (54.67%), Postives = 56/75 (74.67%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            C+ +F+R DEL RH ++H+G +P  C  C + F RSDH  TH+RTHTGEKP++CD+C +RFARSDE+ RH + H 
Sbjct:  244 CERRFSRSDELNRHVRVHTGHRPFQCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVHI 318

HSP 2 Score: 60.8474 bits (146), Expect = 9.760e-10
Identity = 26/56 (46.43%), Postives = 34/56 (60.71%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            EKP  CP   C++ F RSD    H+R HTG +P+ C +C +RF RSD    H +TH
Sbjct:  234 EKPFPCPVENCERRFSRSDELNRHVRVHTGHRPFQCRVCSRRFGRSDHLTTHMRTH 289

HSP 3 Score: 58.151 bits (139), Expect = 7.693e-9
Identity = 26/58 (44.83%), Postives = 32/58 (55.17%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYA 1052
            F C  C  +F R D L  H + H+GEKP SC  C + F RSD RK H R H  ++  A
Sbjct:  267 FQCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVHIKQRERA 324

[Close]

BLAST of SMED30029873 vs. Ensembl Sea Lamprey
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 107.457 bits (267), Expect = 1.098e-26
Identity = 45/75 (60.00%), Postives = 56/75 (74.67%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP +C  C + F RSDH  TH+RTHTGEKP+ACD C +RFARSDE+ RH + H 
Sbjct:  179 CDRRFSRTDELTRHIRIHTGHKPFTCRICMRSFSRSDHLTTHVRTHTGEKPFACDFCGRRFARSDERKRHGRIHL 253

HSP 2 Score: 59.3066 bits (142), Expect = 3.286e-10
Identity = 26/56 (46.43%), Postives = 34/56 (60.71%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
             +P  CP   CD+ F R+D    HIR HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  169 ARPFPCPAEGCDRRFSRTDELTRHIRIHTGHKPFTCRICMRSFSRSDHLTTHVRTH 224

HSP 3 Score: 55.4546 bits (132), Expect = 7.049e-9
Identity = 24/51 (47.06%), Postives = 30/51 (58.82%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H R H
Sbjct:  202 FTCRICMRSFSRSDHLTTHVRTHTGEKPFACDFCGRRFARSDERKRHGRIH 252

[Close]

BLAST of SMED30029873 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000923.1 (pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 gene:ENSPMAG00000000839.1 transcript:ENSPMAT00000000923.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.337 bits (194), Expect = 2.068e-18
Identity = 30/78 (38.46%), Postives = 44/78 (56.41%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKT 1112
            + C  C  +F R     RH ++H+GE+P +C  C + F +  H   H R HTGE+PYAC  C +RFA+     RH ++
Sbjct:   22 YACGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLHTGERPYACAACGRRFAKPYSLTRHLRS 99

HSP 2 Score: 61.6178 bits (148), Expect = 2.864e-12
Identity = 24/57 (42.11%), Postives = 34/57 (59.65%), Query Frame = 3

Query:  945 HSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            H+GE+P +C  C + F R  + + H R HTGE+PYAC  C +RF +      HT+ H
Sbjct:   16 HTGERPYACGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLH 72

HSP 3 Score: 47.7506 bits (112), Expect = 2.094e-7
Identity = 18/34 (52.94%), Postives = 24/34 (70.59%), Query Frame = 3

Query: 1014 THIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            ++IR HTGE+PYAC  C +RFAR   + RH + H
Sbjct:   11 SNIRNHTGERPYACGDCGRRFARGANEERHRRVH 44

[Close]

BLAST of SMED30029873 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000432.1 (pep scaffold:Pmarinus_7.0:GL477956:42837:43256:-1 gene:ENSPMAG00000000389.1 transcript:ENSPMAT00000000432.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.7221 bits (195), Expect = 2.650e-18
Identity = 36/78 (46.15%), Postives = 48/78 (61.54%), Query Frame = 3

Query:  888 STCDVKFTRRDELRRHEKIHSGEKPLSC--PYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            S C   + +   LR H + H+GE+P +C  P C + F RSD  + H RTHTGE+ +AC  C KRFARSD   +H +TH
Sbjct:   43 SGCGKAYGKTSHLRAHLRWHAGERPYACAWPLCARRFTRSDELRRHARTHTGERRFACVACGKRFARSDHLGKHARTH 120

[Close]

BLAST of SMED30029873 vs. Ensembl Sea Lamprey
Match: wt1a (WT1 transcription factor a [Source:ZFIN;Acc:ZDB-GENE-980526-558])

HSP 1 Score: 82.8037 bits (203), Expect = 7.236e-18
Identity = 42/82 (51.22%), Postives = 53/82 (64.63%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGE---KPLSCPYCDKCFIRSDHRKTHIRTHTG---EKPYACDI--CLKRFARSDEKLRHTKTH 1115
            C  +F+R D+L+RH++ H+G    KP  C  CD+ F RSDH KTH RTHTG   EKP+ C    C K+FARSDE +RH   H
Sbjct:  208 CGRRFSRSDQLKRHQRRHTGVTGVKPFQCKMCDRKFARSDHLKTHTRTHTGKPSEKPFVCRWPNCQKKFARSDELVRHHNMH 289

HSP 2 Score: 62.7734 bits (151), Expect = 3.463e-11
Identity = 33/79 (41.77%), Postives = 46/79 (58.23%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPY--CDKCFIRSDHRKTHIRTH---TGEKPYACDICLKRFARSDEKLRHTKTH 1115
            C  ++ +   L+ H + H+GE+P  C Y  C + F RSD  K H R H   TG KP+ C +C ++FARSD    HT+TH
Sbjct:  178 CSKRYFKLSHLQMHCRKHTGERPYQCDYKDCGRRFSRSDQLKRHQRRHTGVTGVKPFQCKMCDRKFARSDHLKTHTRTH 256

HSP 3 Score: 51.6026 bits (122), Expect = 1.437e-7
Identity = 25/58 (43.10%), Postives = 34/58 (58.62%), Query Frame = 3

Query:  954 EKPLSC--PYCDKCFIRSDHRKTHIRTHTGEKPYACDI--CLKRFARSDEKLRHTKTH 1115
             +P  C  P C K + +  H + H R HTGE+PY CD   C +RF+RSD+  RH + H
Sbjct:  168 RRPYMCNYPGCSKRYFKLSHLQMHCRKHTGERPYQCDYKDCGRRFSRSDQLKRHQRRH 225

[Close]

BLAST of SMED30029873 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005004.1 (pep scaffold:Pmarinus_7.0:GL484587:30140:35096:1 gene:ENSPMAG00000004537.1 transcript:ENSPMAT00000005004.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.3445 bits (207), Expect = 7.718e-18
Identity = 36/75 (48.00%), Postives = 52/75 (69.33%), Query Frame = 3

Query:  885 CSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTK 1109
            CS C ++F ++  L+RHEKIHSGEKP +C  C   FI+  H + H RTH+GEKPY CD C + ++R+D+  +H +
Sbjct:   36 CSQCTMRFIQKYLLQRHEKIHSGEKPFTCEQCGMRFIQKYHLERHKRTHSGEKPYECDYCHQYYSRTDQLAKHKR 110

HSP 2 Score: 59.3066 bits (142), Expect = 8.158e-10
Identity = 30/79 (37.97%), Postives = 40/79 (50.63%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            F C  C   F     L+RH  IH+GEK   C  C   FI+    + H + H+GEKP+ C+ C  RF +     RH +TH
Sbjct:    6 FVCERCCAAFRTNYHLQRHVLIHTGEKAYQCSQCTMRFIQKYLLQRHEKIHSGEKPFTCEQCGMRFIQKYHLERHKRTH 84

HSP 3 Score: 50.447 bits (119), Expect = 5.100e-7
Identity = 22/54 (40.74%), Postives = 31/54 (57.41%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRT-HTG 1037
            F C  C ++F ++  L RH++ HSGEKP  C YC + + R+D    H R  H G
Sbjct:   62 FTCEQCGMRFIQKYHLERHKRTHSGEKPYECDYCHQYYSRTDQLAKHKRMCHEG 115

[Close]

BLAST of SMED30029873 vs. Ensembl Yeast
Match: ZAP1 (Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592])

HSP 1 Score: 79.337 bits (194), Expect = 4.278e-16
Identity = 39/77 (50.65%), Postives = 45/77 (58.44%), Query Frame = 3

Query:  885 CSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            C TC   F+  + L +H + HSGEKP  C  C+K F  S   K HIRTHTGEKP  C IC KRF  S    +H KTH
Sbjct:  770 CKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTH 846

HSP 2 Score: 70.0922 bits (170), Expect = 3.433e-13
Identity = 34/74 (45.95%), Postives = 42/74 (56.76%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            C   F +R +L RH K+HS  KP  C  C +CF   +    H RTH+GEKPY C IC K+FA S     H +TH
Sbjct:  745 CHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTH 818

[Close]

BLAST of SMED30029873 vs. Ensembl Yeast
Match: AZF1 (Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639])

HSP 1 Score: 77.411 bits (189), Expect = 1.675e-15
Identity = 34/77 (44.16%), Postives = 43/77 (55.84%), Query Frame = 3

Query:  885 CSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            C  C   F++   L  H + H G KP  C YC K F +  + +TH R HTGEKPY+CDIC K+F+R      H  TH
Sbjct:  595 CPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTH 671

HSP 2 Score: 70.0922 bits (170), Expect = 2.902e-13
Identity = 33/81 (40.74%), Postives = 44/81 (54.32%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDI--CLKRFARSDEKLRHTKTH 1115
            F C  C  +FT+   LR HE++H+GEKP SC  CDK F R  +   H+ TH   KP+ C +  C K F     +L + K H
Sbjct:  621 FVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFT----QLGNMKAH 697

[Close]

BLAST of SMED30029873 vs. Ensembl Yeast
Match: CRZ1 (Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972])

HSP 1 Score: 75.0998 bits (183), Expect = 7.486e-15
Identity = 37/87 (42.53%), Postives = 43/87 (49.43%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACD---------ICLKRFARSDEKLRHTKT 1112
            F C  C  KFTR   L+ H + H+ E+P  C  C K F R   RK H   HTG+K Y C           C K+FARSD   RH KT
Sbjct:  569 FACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKT 655

HSP 2 Score: 56.9954 bits (136), Expect = 3.289e-9
Identity = 23/51 (45.10%), Postives = 31/51 (60.78%), Query Frame = 3

Query:  963 LSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
             +C  C K F R  + K+H+RTHT E+P+ C IC K FAR  ++ RH   H
Sbjct:  569 FACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLH 619

HSP 3 Score: 50.0618 bits (118), Expect = 6.219e-7
Identity = 23/64 (35.94%), Postives = 33/64 (51.56%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSC--------PY-CDKCFIRSDHRKTHIRTHTGEK 1043
            F CS C   F R+ + +RHE +H+G+K   C        P+ C K F RSD    H +T +G +
Sbjct:  597 FICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRR 660

[Close]

BLAST of SMED30029873 vs. Ensembl Yeast
Match: MIG1 (Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state [Source:SGD;Acc:S000003003])

HSP 1 Score: 72.4034 bits (176), Expect = 4.392e-14
Identity = 29/55 (52.73%), Postives = 39/55 (70.91%), Query Frame = 3

Query:  957 KPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDI--CLKRFARSDEKLRHTKTH 1115
            +P +CP C + F R +H+  H+R HTGEKP+ACD   C+KRF+RSDE  RH + H
Sbjct:   36 RPHACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIH 90

HSP 2 Score: 50.447 bits (119), Expect = 3.277e-7
Identity = 25/59 (42.37%), Postives = 29/59 (49.15%), Query Frame = 3

Query:  882 CCSTCDVKFTRRDELRRHEKIHSGEKPLSC--PYCDKCFIRSDHRKTHIRTHTGEKPYA 1052
             C  C   F R +   RH +IH+GEKP +C  P C K F RSD    H R HT   P  
Sbjct:   39 ACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHPRG 97

[Close]

BLAST of SMED30029873 vs. Ensembl Yeast
Match: MSN2 (Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress [Source:SGD;Acc:S000004640])

HSP 1 Score: 68.1662 bits (165), Expect = 1.048e-12
Identity = 29/55 (52.73%), Postives = 38/55 (69.09%), Query Frame = 3

Query:  954 EKPLSCPYCDKCFIRSDHRKTHIRT-HTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            EKP  C  C K F RS+H K H+R+ H+ E+P+AC IC K+F+RSD   +H KTH
Sbjct:  644 EKPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTH 698

HSP 2 Score: 56.9954 bits (136), Expect = 3.711e-9
Identity = 24/52 (46.15%), Postives = 32/52 (61.54%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEK-IHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F R + L+RH + +HS E+P +C  CDK F RSD+   HI+TH
Sbjct:  647 FHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTH 698

[Close]

BLAST of SMED30029873 vs. Ensembl Nematostella
Match: EDO49112 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGT8])

HSP 1 Score: 97.8265 bits (242), Expect = 4.906e-25
Identity = 45/76 (59.21%), Postives = 55/76 (72.37%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            TC  +F+R DEL RH + H+G+KP  C  C + F RSDH  THIRTHTGEKP+AC+ C +RFARSDE+ RH K H 
Sbjct:   10 TCPRRFSRSDELTRHMRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACETCGRRFARSDERRRHMKIHL 85

HSP 2 Score: 47.7506 bits (112), Expect = 2.789e-7
Identity = 23/54 (42.59%), Postives = 31/54 (57.41%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGE 1040
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD R+ H++ H  E
Sbjct:   34 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACETCGRRFARSDERRRHMKIHLRE 87

[Close]

BLAST of SMED30029873 vs. Ensembl Nematostella
Match: EDO32290 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVG8])

HSP 1 Score: 79.337 bits (194), Expect = 2.163e-18
Identity = 36/76 (47.37%), Postives = 47/76 (61.84%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            C+  + +   L+ H + H+GE+P  C +  C+K F RSD    H RTHTGEK Y C IC KRF RSD   +H+KTH
Sbjct:   12 CNKIYGKSSHLKAHTRTHTGERPFMCTWKDCEKRFARSDELARHYRTHTGEKRYVCKICDKRFMRSDHLSKHSKTH 87

[Close]

BLAST of SMED30029873 vs. Ensembl Nematostella
Match: EDO34637 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNP5])

HSP 1 Score: 77.7962 bits (190), Expect = 1.339e-17
Identity = 32/75 (42.67%), Postives = 47/75 (62.67%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRH 1103
            + C+ CD KF R+ ++++H  +H+G KP  C  C K F +S +  TH+R HTG KP+ C IC +RF R  +  RH
Sbjct:   40 YACTYCDKKFLRKSDMKKHTLMHTGAKPFQCKQCGKVFSQSSNMLTHMRRHTGIKPFPCKICGRRFYRKVDVRRH 114

HSP 2 Score: 72.7886 bits (177), Expect = 9.616e-16
Identity = 34/79 (43.04%), Postives = 42/79 (53.16%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            F C  C  +F R   L  H+ IHS  KP +C YCDK F+R    K H   HTG KP+ C  C K F++S   L H + H
Sbjct:   12 FRCLECGKEFRRPSSLSTHKLIHSDHKPYACTYCDKKFLRKSDMKKHTLMHTGAKPFQCKQCGKVFSQSSNMLTHMRRH 90

HSP 3 Score: 44.2838 bits (103), Expect = 8.629e-6
Identity = 22/61 (36.07%), Postives = 27/61 (44.26%), Query Frame = 3

Query:  933 HEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            H      E+   C  C K F R     TH   H+  KPYAC  C K+F R  +  +HT  H
Sbjct:    2 HSAKDEKERVFRCLECGKEFRRPSSLSTHKLIHSDHKPYACTYCDKKFLRKSDMKKHTLMH 62

[Close]

BLAST of SMED30029873 vs. Ensembl Nematostella
Match: EDO28606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNP5])

HSP 1 Score: 77.7962 bits (190), Expect = 1.339e-17
Identity = 32/75 (42.67%), Postives = 47/75 (62.67%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRH 1103
            + C+ CD KF R+ ++++H  +H+G KP  C  C K F +S +  TH+R HTG KP+ C IC +RF R  +  RH
Sbjct:   40 YACTYCDKKFLRKSDMKKHTLMHTGAKPFQCKQCGKVFSQSSNMLTHMRRHTGIKPFPCKICGRRFYRKVDVRRH 114

HSP 2 Score: 72.7886 bits (177), Expect = 9.616e-16
Identity = 34/79 (43.04%), Postives = 42/79 (53.16%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            F C  C  +F R   L  H+ IHS  KP +C YCDK F+R    K H   HTG KP+ C  C K F++S   L H + H
Sbjct:   12 FRCLECGKEFRRPSSLSTHKLIHSDHKPYACTYCDKKFLRKSDMKKHTLMHTGAKPFQCKQCGKVFSQSSNMLTHMRRH 90

HSP 3 Score: 44.2838 bits (103), Expect = 8.629e-6
Identity = 22/61 (36.07%), Postives = 27/61 (44.26%), Query Frame = 3

Query:  933 HEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            H      E+   C  C K F R     TH   H+  KPYAC  C K+F R  +  +HT  H
Sbjct:    2 HSAKDEKERVFRCLECGKEFRRPSSLSTHKLIHSDHKPYACTYCDKKFLRKSDMKKHTLMH 62

[Close]

BLAST of SMED30029873 vs. Ensembl Nematostella
Match: EDO42939 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S017])

HSP 1 Score: 77.0258 bits (188), Expect = 1.781e-17
Identity = 35/76 (46.05%), Postives = 46/76 (60.53%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCP--YCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            C   + +   L+ H + H+GE+P  C   +C K F RSD  + H+RTHTGEK + CD C KRF RSD   +H KTH
Sbjct:   15 CGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFQCDECGKRFMRSDHLRKHQKTH 90

HSP 2 Score: 55.8398 bits (133), Expect = 5.030e-10
Identity = 24/50 (48.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:  972 PYCDKCFIRSDHRKTHIRTHTGEKPYACD--ICLKRFARSDEKLRHTKTH 1115
            P C K + ++ H K H+R HTGE+P+ C+   C K F RSDE  RH +TH
Sbjct:   13 PGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTH 62

[Close]

BLAST of SMED30029873 vs. Ensembl Medaka
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100272163])

HSP 1 Score: 114.775 bits (286), Expect = 3.345e-27
Identity = 48/76 (63.16%), Postives = 59/76 (77.63%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            TCD +F+R DEL RH +IH+G+KP  C  C + F RSDH  THIRTHTGEKP+AC+IC ++FARSDE+ RHTK H 
Sbjct:  319 TCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHL 394

HSP 2 Score: 56.6102 bits (135), Expect = 3.000e-8
Identity = 24/55 (43.64%), Postives = 31/55 (56.36%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C  C + F RSD RK H + H  +K
Sbjct:  343 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHLRQK 397

[Close]

BLAST of SMED30029873 vs. Ensembl Medaka
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:101170128])

HSP 1 Score: 109.768 bits (273), Expect = 1.139e-25
Identity = 47/75 (62.67%), Postives = 56/75 (74.67%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP+ACD C ++FARSDE+ RHTK H 
Sbjct:  337 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHL 411

HSP 2 Score: 62.7734 bits (151), Expect = 3.364e-10
Identity = 28/56 (50.00%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            E+P  CP   CD+ F RSD    HIR HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  327 ERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 382

HSP 3 Score: 56.6102 bits (135), Expect = 3.014e-8
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP +C +C + F RSD RK H + H  +K
Sbjct:  360 FQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQK 414

[Close]

BLAST of SMED30029873 vs. Ensembl Medaka
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:100272164])

HSP 1 Score: 107.842 bits (268), Expect = 3.577e-25
Identity = 44/75 (58.67%), Postives = 55/75 (73.33%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP++C+ C ++FARSDE+ RH K H 
Sbjct:  303 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHL 377

HSP 2 Score: 63.1586 bits (152), Expect = 2.354e-10
Identity = 27/56 (48.21%), Postives = 36/56 (64.29%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            E+P +CP   CD+ F RSD    H+R HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  293 ERPHACPAENCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTH 348

HSP 3 Score: 59.3066 bits (142), Expect = 3.490e-9
Identity = 25/55 (45.45%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC +C + F RSD RK H + H  +K
Sbjct:  326 FQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 380

[Close]

BLAST of SMED30029873 vs. Ensembl Medaka
Match: ENSORLT00000034291.1 (early growth response protein 2b [Source:NCBI gene;Acc:101164744])

HSP 1 Score: 103.605 bits (257), Expect = 8.313e-24
Identity = 44/76 (57.89%), Postives = 55/76 (72.37%), Query Frame = 3

Query:  891 TCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            +CD +F+R DEL RH +IH+G KP  C  C + F RSDH  THIRTHTGEKP++C  C ++FARSDE+ RH K H 
Sbjct:  310 SCDRRFSRSDELSRHLRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFSCQQCGRKFARSDERRRHMKIHL 385

HSP 2 Score: 60.077 bits (144), Expect = 1.776e-9
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  954 EKPLSCPY--CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            ++P  CP   CD+ F RSD    H+R HTG KP+ C IC++ F+RSD    H +TH
Sbjct:  301 QRPYPCPAESCDRRFSRSDELSRHLRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 356

HSP 3 Score: 55.0694 bits (131), Expect = 7.213e-8
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEK 1043
            F C  C   F+R D L  H + H+GEKP SC  C + F RSD R+ H++ H  +K
Sbjct:  334 FQCRICMRNFSRSDHLTTHIRTHTGEKPFSCQQCGRKFARSDERRRHMKIHLRQK 388

[Close]

BLAST of SMED30029873 vs. Ensembl Medaka
Match: ENSORLT00000000940.2 (early growth response protein 1 [Source:NCBI gene;Acc:101160576])

HSP 1 Score: 104.375 bits (259), Expect = 9.640e-24
Identity = 42/74 (56.76%), Postives = 54/74 (72.97%), Query Frame = 3

Query:  894 CDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            C+ +F+R DEL RH ++H+G+KP  C  C + F RSDH  THIRTHTGEKP+ C  C ++FARSDE+ RH K H
Sbjct:  290 CERRFSRSDELTRHVRVHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFPCSECGRKFARSDERKRHAKIH 363

HSP 2 Score: 53.9138 bits (128), Expect = 2.010e-7
Identity = 23/51 (45.10%), Postives = 28/51 (54.90%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTH 1031
            F C  C   F+R D L  H + H+GEKP  C  C + F RSD RK H + H
Sbjct:  313 FQCRICMRSFSRSDHLTTHIRTHTGEKPFPCSECGRKFARSDERKRHAKIH 363

[Close]

BLAST of SMED30029873 vs. Planmine SMEST
Match: SMESG000042500.1 (SMESG000042500.1)

HSP 1 Score: 794.653 bits (2051), Expect = 0.000e+0
Identity = 423/425 (99.53%), Postives = 424/425 (99.76%), Query Frame = 3

Query:   78 MLDLGIDQMYNATNVPCVGKIEKDCFSLDTPKECNDSKLSQNXXXXXXXXXXEFNGDPLCDYSDMLLNSEETNPEYTFQHSFSDDSSILSFPEQRSPTGSLNDIEIKLELQNNSMQFQGLENLRNYEIQGISNYSTYSNYNKLPPIIFQPFLQAYNSLMNPTMDGCYNYPIMSNNSNLMSLPRDTIVYVPTPVRNLQPNMYFNQQYNMSSDNYALDTTPDLQTTSINTPMICQAEISNTMPVLDISQQSTIIDXXXXXXXXXXXXXXFCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHFXXXXXXXXXKKINEPEYFTSVTINNTLEDPSINYSNISKEQTIYYDDSNLQQIFSVQNPEYVNETSFSPLFLEHLWNN 1352
            MLDLGIDQMYNATNVPCVGKIEKDCFSLDTPKECNDSKLSQNLFSDSLFDFSEFNGDPLCDYSDMLLNSEETNPEYTFQHSFSDDSSILSFPEQRSPT SLNDIEIKLELQNNSMQFQGLENLRNYEIQGISNYSTYSNYNKLPPIIFQPFLQAYNSL+NPTMDGCYNYPIMSNNSNLMSLPRDTIVYVPTPVRNLQPNMYFNQQYNMSSDNYALDTTPDLQTTSINTPMICQAEISNTMPVLDISQQSTIIDKPVKTKKVVQTEKTFCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHFRERPRRRRRKKINEPEYFTSVTINNTLEDPSINYSNISKEQTIYYDDSNLQQIFSVQNPEYVNETSFSPLFLEHLWNN
Sbjct:    1 MLDLGIDQMYNATNVPCVGKIEKDCFSLDTPKECNDSKLSQNLFSDSLFDFSEFNGDPLCDYSDMLLNSEETNPEYTFQHSFSDDSSILSFPEQRSPTSSLNDIEIKLELQNNSMQFQGLENLRNYEIQGISNYSTYSNYNKLPPIIFQPFLQAYNSLVNPTMDGCYNYPIMSNNSNLMSLPRDTIVYVPTPVRNLQPNMYFNQQYNMSSDNYALDTTPDLQTTSINTPMICQAEISNTMPVLDISQQSTIIDKPVKTKKVVQTEKTFCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHFRERPRRRRRKKINEPEYFTSVTINNTLEDPSINYSNISKEQTIYYDDSNLQQIFSVQNPEYVNETSFSPLFLEHLWNN 425

[Close]

BLAST of SMED30029873 vs. Planmine SMEST
Match: SMESG000028801.1 (SMESG000028801.1)

HSP 1 Score: 150.984 bits (380), Expect = 1.068e-41
Identity = 65/80 (81.25%), Postives = 70/80 (87.50%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            F C  C  KF+RRDEL+RHEKIHSGEKPLSCPYCDKCF+RSDHR THIRTHTGEKPY+CDIC KRFARSDEKLRH + H 
Sbjct:  178 FPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHL 257

[Close]

BLAST of SMED30029873 vs. Planmine SMEST
Match: SMESG000028801.1 (SMESG000028801.1)

HSP 1 Score: 150.599 bits (379), Expect = 2.472e-41
Identity = 65/80 (81.25%), Postives = 70/80 (87.50%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 1118
            F C  C  KF+RRDEL+RHEKIHSGEKPLSCPYCDKCF+RSDHR THIRTHTGEKPY+CDIC KRFARSDEKLRH + H 
Sbjct:  203 FPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHL 282

[Close]

BLAST of SMED30029873 vs. Planmine SMEST
Match: SMESG000034285.1 (SMESG000034285.1)

HSP 1 Score: 136.732 bits (343), Expect = 1.268e-35
Identity = 59/79 (74.68%), Postives = 67/79 (84.81%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            F CS C  +FTR+DELRRHEKIH+G K L CPYCDK FIRSDHR+THIRTHTGEKPY+C+IC K FARSDE+ RHT+ H
Sbjct:  182 FTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 260

[Close]

BLAST of SMED30029873 vs. Planmine SMEST
Match: SMESG000000960.1 (SMESG000000960.1)

HSP 1 Score: 115.546 bits (288), Expect = 6.371e-30
Identity = 50/81 (61.73%), Postives = 63/81 (77.78%), Query Frame = 3

Query:  879 FCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTK-THF 1118
            F C+TC   F RRDEL+RHE+IH+GE+PL+C +CDK F+RSDH  TH+R HTGEKPY C  C + F+RSDE+LRH + TH 
Sbjct:  106 FTCNTCKKSFYRRDELKRHERIHTGERPLACHFCDKRFMRSDHLSTHVRIHTGEKPYQCSYCDRLFSRSDERLRHIRQTHL 186

HSP 2 Score: 56.225 bits (134), Expect = 5.665e-9
Identity = 26/53 (49.06%), Postives = 29/53 (54.72%), Query Frame = 3

Query:  957 KPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 1115
            K  +C  C K F R D  K H R HTGE+P AC  C KRF RSD    H + H
Sbjct:  104 KQFTCNTCKKSFYRRDELKRHERIHTGERPLACHFCDKRFMRSDHLSTHVRIH 156

The following BLAST results are available for this feature:

BLAST of SMED30029873 vs. Ensembl Human
BLAST of SMED30029873 vs. Ensembl Celegans
BLAST of SMED30029873 vs. Ensembl Fly
BLAST of SMED30029873 vs. Ensembl Zebrafish
BLAST of SMED30029873 vs. Ensembl Xenopus
BLAST of SMED30029873 vs. Ensembl Mouse
BLAST of SMED30029873 vs. UniProt/SwissProt
BLAST of SMED30029873 vs. TrEMBL
BLAST of SMED30029873 vs. Ensembl Cavefish
BLAST of SMED30029873 vs. Ensembl Sea Lamprey
BLAST of SMED30029873 vs. Ensembl Yeast
BLAST of SMED30029873 vs. Ensembl Nematostella
BLAST of SMED30029873 vs. Ensembl Medaka
BLAST of SMED30029873 vs. Planmine SMEST

BLAST of SMED30029873 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EGR1	1.625e-27	63.16	early growth response 1 [Source:HGNC Symbol;Acc:HG...	[more]
EGR3	1.639e-25	60.00	early growth response 3 [Source:HGNC Symbol;Acc:HG...	[more]
EGR3	2.560e-25	60.00	early growth response 3 [Source:HGNC Symbol;Acc:HG...	[more]
EGR2	4.236e-25	62.67	early growth response 2 [Source:HGNC Symbol;Acc:HG...	[more]
EGR2	4.236e-25	62.67	early growth response 2 [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of SMED30029873 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egrh-2	1.036e-27	64.86	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	2.031e-27	64.86	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	2.144e-27	64.86	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	5.313e-27	64.86	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-1	6.349e-27	62.16	EGR (Early Growth factor Response factor) Homolog ...	[more]

BLAST of SMED30029873 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sr	2.162e-27	62.67	gene:FBgn0003499 transcript:FBtr0330050	[more]
sr	2.200e-27	62.67	gene:FBgn0003499 transcript:FBtr0083542	[more]
sr	4.920e-27	62.67	gene:FBgn0003499 transcript:FBtr0301615	[more]
sr	6.608e-27	62.67	gene:FBgn0003499 transcript:FBtr0344633	[more]
sr	6.608e-27	62.67	gene:FBgn0003499 transcript:FBtr0083543	[more]

BLAST of SMED30029873 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	1.901e-27	63.16	early growth response 1 [Source:NCBI gene;Acc:3049...	[more]
egr1	1.901e-27	63.16	early growth response 1 [Source:NCBI gene;Acc:3049...	[more]
egr4	8.841e-27	57.89	early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
egr2b	7.993e-26	62.67	early growth response 2b [Source:NCBI gene;Acc:301...	[more]
egr2a	9.057e-26	62.16	early growth response 2a [Source:ZFIN;Acc:ZDB-GENE...	[more]

BLAST of SMED30029873 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	7.190e-28	63.16	early growth response 1 [Source:NCBI gene;Acc:1000...	[more]
egr1	8.391e-28	63.16	early growth response 1 [Source:NCBI gene;Acc:1000...	[more]
serpinb4	3.822e-26	61.33	serpin peptidase inhibitor, clade B (ovalbumin), m...	[more]
tbl1x	1.826e-25	62.67	transducin beta like 1 X-linked [Source:Xenbase;Ac...	[more]
usp31	3.903e-24	58.54	ubiquitin specific peptidase 31 [Source:Xenbase;Ac...	[more]

BLAST of SMED30029873 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Egr1	1.026e-27	63.16	early growth response 1 [Source:MGI Symbol;Acc:MGI...	[more]
Egr1	1.026e-27	63.16	early growth response 1 [Source:MGI Symbol;Acc:MGI...	[more]
Egr3	1.073e-25	60.00	early growth response 3 [Source:MGI Symbol;Acc:MGI...	[more]
Egr3	1.707e-25	60.00	early growth response 3 [Source:MGI Symbol;Acc:MGI...	[more]
Egr4	1.744e-25	58.54	early growth response 4 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of SMED30029873 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O73693\|EGR1_TAEGU	9.732e-28	64.00	Early growth response protein 1 (Fragment) OS=Taen...	[more]
sp\|O73692\|EGR1_COTJA	1.451e-27	64.00	Early growth response protein 1 (Fragment) OS=Cotu...	[more]
sp\|O73691\|EGR1_CHICK	3.283e-27	64.00	Early growth response protein 1 (Fragment) OS=Gall...	[more]
sp\|A4II20\|EGR1_XENTR	3.809e-27	63.16	Early growth response protein 1 OS=Xenopus tropica...	[more]
sp\|Q6GQH4\|EGR1A_XENLA	6.744e-27	63.16	Early growth response protein 1-A OS=Xenopus laevi...	[more]

BLAST of SMED30029873 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZI72	4.983e-38	81.25	Early growth response-4 OS=Schmidtea mediterranea ...	[more]
H9CXV3	4.294e-32	74.68	EGR-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
T1DF98	1.343e-27	67.53	Egrl-3 (Fragment) OS=Dendrocoelum lacteum OX=27895...	[more]
T1E116	8.417e-27	65.38	Egrl-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1	[more]
G1CSV5	2.291e-26	61.73	EGR-like protein 1 OS=Schmidtea mediterranea OX=79...	[more]

BLAST of SMED30029873 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	3.211e-27	63.16	early growth response 1 [Source:NCBI gene;Acc:1030...	[more]
EGR2	6.334e-26	60.81	early growth response protein 2b-like [Source:NCBI...	[more]
egr2b	7.844e-26	62.67	early growth response 2 [Source:NCBI gene;Acc:1030...	[more]
egr3	4.052e-25	58.67	early growth response 3 [Source:NCBI gene;Acc:1030...	[more]
egr4	2.226e-24	54.67	early growth response protein 1-B [Source:NCBI gen...	[more]

BLAST of SMED30029873 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr4	1.098e-26	60.00	early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
ENSPMAT00000000923.1	2.068e-18	38.46	pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 ...	[more]
ENSPMAT00000000432.1	2.650e-18	46.15	pep scaffold:Pmarinus_7.0:GL477956:42837:43256:-1 ...	[more]
wt1a	7.236e-18	51.22	WT1 transcription factor a [Source:ZFIN;Acc:ZDB-GE...	[more]
ENSPMAT00000005004.1	7.718e-18	48.00	pep scaffold:Pmarinus_7.0:GL484587:30140:35096:1 g...	[more]

BLAST of SMED30029873 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
ZAP1	4.278e-16	50.65	Zinc-regulated transcription factor; binds to zinc...	[more]
AZF1	1.675e-15	44.16	Zinc-finger transcription factor; involved in diau...	[more]
CRZ1	7.486e-15	42.53	Transcription factor, activates transcription of s...	[more]
MIG1	4.392e-14	52.73	Transcription factor involved in glucose repressio...	[more]
MSN2	1.048e-12	52.73	Stress-responsive transcriptional activator; activ...	[more]

BLAST of SMED30029873 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49112	4.906e-25	59.21	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32290	2.163e-18	47.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34637	1.339e-17	42.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28606	1.339e-17	42.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42939	1.781e-17	46.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30029873 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	3.345e-27	63.16	early growth response 1 [Source:NCBI gene;Acc:1002...	[more]
egr2b	1.139e-25	62.67	early growth response 2 [Source:NCBI gene;Acc:1011...	[more]
egr3	3.577e-25	58.67	early growth response 3 [Source:NCBI gene;Acc:1002...	[more]
ENSORLT00000034291.1	8.313e-24	57.89	early growth response protein 2b [Source:NCBI gene...	[more]
ENSORLT00000000940.2	9.640e-24	56.76	early growth response protein 1 [Source:NCBI gene;...	[more]

BLAST of SMED30029873 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000042500.1	0.000e+0	99.53	SMESG000042500.1	[more]
SMESG000028801.1	1.068e-41	81.25	SMESG000028801.1	[more]
SMESG000028801.1	2.472e-41	81.25	SMESG000028801.1	[more]
SMESG000034285.1	1.268e-35	74.68	SMESG000034285.1	[more]
SMESG000000960.1	6.371e-30	61.73	SMESG000000960.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30029873 ID=SMED30029873|Name=SMED30029873|organism=Schmidtea mediterranea sexual|type=transcript|length=1415bp
CAATTTAGAATTTTATGAAATTGCTTTAAGCACTAAGGGTTTTAATCAAC
AGTGAACAATAAAATTAAGATTTTTGAATGCTTGATTTAGGAATAGATCA
AATGTACAATGCGACAAATGTGCCATGTGTAGGGAAAATAGAGAAAGACT
GTTTCTCCCTTGATACTCCTAAAGAGTGCAATGATTCAAAATTAAGTCAA
AATCTTTTCAGCGACTCCCTATTTGATTTTTCAGAATTCAATGGAGATCC
CTTGTGTGATTATTCTGATATGCTTTTGAATTCAGAGGAAACCAATCCAG
AATATACATTTCAGCATTCCTTTTCAGATGATTCGTCAATACTTTCATTC
CCAGAGCAAAGGAGTCCGACTGGTAGTTTAAATGACATTGAAATCAAACT
TGAATTACAGAACAATTCCATGCAATTTCAAGGTCTCGAAAATCTAAGAA
ATTACGAAATCCAGGGAATTAGCAATTACTCCACATATTCAAATTACAAT
AAATTGCCTCCAATTATTTTCCAACCATTTCTTCAAGCATATAATTCCCT
GATGAACCCTACAATGGATGGTTGTTATAATTATCCTATCATGTCAAATA
ATTCCAATTTAATGAGCCTTCCAAGAGACACAATAGTTTATGTGCCTACT
CCTGTGCGAAATTTACAGCCCAATATGTATTTTAACCAGCAGTATAATAT
GAGTTCAGATAACTACGCACTAGACACCACGCCGGACCTTCAAACAACAT
CAATTAATACCCCAATGATCTGCCAGGCAGAAATTTCAAATACCATGCCA
GTTCTCGACATAAGTCAACAATCCACAATCATCGATAAACCTGTTAAAAC
AAAAAAAGTTGTACAAACTGAAAAGACATTTTGTTGCTCAACTTGTGACG
TAAAATTCACAAGACGAGATGAACTGCGTCGTCACGAAAAAATCCACAGC
GGTGAGAAACCCCTTTCCTGTCCGTATTGTGATAAATGTTTCATAAGGTC
TGACCATAGGAAAACTCATATTCGAACACATACCGGCGAAAAACCATATG
CCTGTGATATTTGTTTGAAAAGATTTGCTAGGTCCGATGAGAAATTACGA
CACACCAAAACCCATTTTCGAGAAAGACCAAGAAGGCGACGACGAAAGAA
GATCAATGAACCAGAATATTTTACTAGCGTTACAATCAACAACACTCTCG
AGGATCCATCTATCAACTATAGCAATATTTCAAAAGAACAAACCATTTAC
TATGACGACAGCAATCTTCAACAAATCTTTTCCGTTCAAAATCCCGAATA
CGTTAACGAAACTTCTTTTTCTCCATTATTTTTAGAACATTTATGGAACA
ATTAATTTATTTTTCACGCTTACTAGTACTAGTATTAAAATTGTTTTGAG
TTTTTTTGATACAAC

protein sequence of SMED30029873-orf-1

>SMED30029873-orf-1 ID=SMED30029873-orf-1|Name=SMED30029873-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=426bp
MLDLGIDQMYNATNVPCVGKIEKDCFSLDTPKECNDSKLSQNLFSDSLFD
FSEFNGDPLCDYSDMLLNSEETNPEYTFQHSFSDDSSILSFPEQRSPTGS
LNDIEIKLELQNNSMQFQGLENLRNYEIQGISNYSTYSNYNKLPPIIFQP
FLQAYNSLMNPTMDGCYNYPIMSNNSNLMSLPRDTIVYVPTPVRNLQPNM
YFNQQYNMSSDNYALDTTPDLQTTSINTPMICQAEISNTMPVLDISQQST
IIDKPVKTKKVVQTEKTFCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPY
CDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHFRER
PRRRRRKKINEPEYFTSVTINNTLEDPSINYSNISKEQTIYYDDSNLQQI
FSVQNPEYVNETSFSPLFLEHLWNN*

Aliases

The feature 'SMED30029873' has the following synonyms


Synonym
EGR-5

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000028	Category 2 cell
PLANA:0000034	epidermis
PLANA:0000035	Category 3 cell
PLANA:0002032	epidermal cell
PLANA:0002109	X1 cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR036236	Znf_C2H2_sf
IPR001878	Znf_CCHC
IPR015880	Znf_C2H2-like
IPR013087	Znf_C2H2_type
IPR007087	Znf_C2H2

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013087	Zinc finger C2H2-type	SMART	SM00355	c2h2final6	coord: 324..346 e-value: 0.12 score: 21.5 coord: 268..290 e-value: 0.0098 score: 25.1 coord: 296..318 e-value: 0.069 score: 22.3
IPR013087	Zinc finger C2H2-type	PFAM	PF00096	zf-C2H2	coord: 268..290 e-value: 0.0072 score: 16.7 coord: 297..318 e-value: 3.5E-4 score: 20.9
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 269..290
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 326..346
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 298..318
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 268..295 score: 15.313
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 296..323 score: 14.253
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 324..351 score: 12.591
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 266..295 e-value: 1.9E-9 score: 39.2
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 322..351 e-value: 1.3E-10 score: 42.8
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 296..321 e-value: 2.0E-12 score: 48.4
None	No IPR available	PANTHER	PTHR23235	TRANSCRIPTION FACTOR SP3	coord: 254..358
None	No IPR available	PANTHER	PTHR23235:SF60	STRIPE, ISOFORM D	coord: 254..358
IPR036236	Zinc finger C2H2 superfamily	SUPERFAMILY	SSF57667	beta-beta-alpha zinc fingers	coord: 260..305
IPR036236	Zinc finger C2H2 superfamily	SUPERFAMILY	SSF57667	beta-beta-alpha zinc fingers	coord: 294..346