Polypeptide N-acetylgalactosaminyltransferase

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKT-QWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q   +GPGE G+ V +  E+ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y ++LPTTSV+I+FHNEAWS LLRT HSV+NRSP   ++E++L DD+S +  L   LE+YVK  + P   V ++R + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L ++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   52 QKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVP---VHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIP-RHYFSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVTMLKC-HHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGSRS-QQW 548          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYH-GLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q+GPGE G+ V +  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAWS LLRT +SV+NRSP   L EVIL DD+S +  L   LE YVK    +  V+I+R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI + R+T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PYTFPG   +    N++R+ +VW+D++K  FY+  P + + + G++S R  LR +L+CK F W+++N+ P+  IP R     G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  +  NG V  + C   +   QLW Y+ E  +L ++   QCLD  + ++    T+Q C  S   Q+W
Sbjct:   54 QEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNL--EVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIP-RRYYSLGEIRNVETNQCLDNMGRKE----NEKVGIFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLNGPVIMLKC-HHMRGNQLWEYDAERLTLRHVNSNQCLDEPSEEDKMVPTMQDCSGSRS-QQW 547          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYH-GLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDR-VTIQPCESSNPYQKW 1881
            Q+GPGE G+ V +  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAWS LLRT +SV+NRSP   L EVIL DD+S +  L   LE YVK    +  V+I+R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI + R+T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PYTFPG   +    N++R+ +VW+D++K  FY+  P + + + G++S R  LR +L+CK F W+++N+ P+  IP R     G ++N ++N CLD + + E    N   G+++C  G    Q+FS +  K               +IR +  CL  +  NG V  + C   +   QLW Y+ E+          CL  + + +  +  T++ C  S   QKW
Sbjct:   54 QEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNL--EVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIP-RRYYSLGEIRNVETNQCLDNMGRKE----NEKVGIFNCH-GMGGNQVFSYTADK---------------EIRTDDLCLDVSRLNGPVIMLKC-HHMRGNQLWEYDAES----------CLSVNKVADGSQHPTVETCNDST-LQKW 538          

Query:  184 NKFKISDSKLNNDLNVKDTSFLLALGINI------------STYNYRANRYHIYNTNQYYQKGPGENGELVSLTD---EENKNLDDVMKKEAFNRPTSDRISLQRSL-PDFRNSEC--KAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQ---VGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPE----LREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCV-----TELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            NK K+ D  L    N+KD    + +G  +              Y   A    + +        PG +G+    T+   EE K  +    K  FN   SDRISL R L PD R  EC  + F     LPTTSVII+FHNEAWS LLRT HSV+  SP   LKE+IL DD+S    L  +L+ YVK     ++V+IVR + R GLI ARL GA  A  E L FLD+HCE   GWLEP+L RI +    ++ P I SID   F +   +  G     G F WS+ F W+ +P+H K+  K +T  +K+ T AGGLF+  ++YF  IGSYDE MEIWGGEN+E+SFR W CGG LE  PCS VGH+FR+  P++FP        N  R+ +VW+D+YK +FY    +    +++   G++S R ++++ LQCK+F W++ N+ PE ++PD N +  GY+K+    LCLD+    E ++G     +Y+C +G    Q F  S         ++I+ N    I++E  CL A +  G V    C      T +   Q+W   K+   L N   K CL A    N +  ++  C  S+P QKW
Sbjct:   58 NKNKMLDLMLEAVNNIKDAMPKMQIGAPVRQNIDAGERPCLQGYYTAAELKPVLDRPPQDSNAPGASGKAFKTTNLSVEEQKEKERGEAKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNEAWSTLLRTVHSVLYSSPAILLKEIILVDDASVDEYLHDKLDEYVKQ---FSIVKIVRQRERKGLITARLLGATVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPSPYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETYPIKTPTFAGGLFSISKEYFEYIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHVFRSKSPHSFPKGTQVIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKAFGDLSKRFEIKHRLQCKNFTWYLNNIYPEVYVPDLNPVISGYIKSVGQPLCLDV---GENNQGGKPLIMYTC-HGLGGNQYFEYSA-------QHEIRHN----IQKEL-CLHAAQ--GLVQLKACTYKGHKTVVTGEQIWEIQKDQ-LLYNPFLKMCLSA----NGEHPSLVSCNPSDPLQKW 627          

Query:  334 GPGENGELVS---LTDEENKNLDDVMKKEAFNRPTSDRISLQRSL-PDFRNSEC--KAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQV---GTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPE----LREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENN---GKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
             PG +G+       T  E +  ++  KK  FN   SDRISLQRSL PD R  EC  + F     L TTSVII+FHNEAWS LLRT +SV++ +P   LKE+IL DD+S +  L  +LE YVK      VVR+VR + R GLI ARL GA  A  EVL FLD+HCE   GWLEP+L RI + +  ++ P I +ID   F +      G+V   G F WS+ F W+ +P H K+  K +T  +KS T AGGLF+  + YF  IG+YD  MEIWGGEN+E+SFR W CGG LE  PCS VGH+FR   P+TFP        N  R+ +VW+D YK++FY    +     +E + G+IS R++LR  L C +F W++ NV PE F+PD     YG +KN  +N CLD+    E +RG     +YSC +G    Q F         +   D++ N   Q+     CL  ++     G   F    +++ + + W   ++   + N     CL + + K      + PC  S+P+Q W
Sbjct:  112 APGADGKAFQKSKWTPLETQEKEEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLATTSVIIVFHNEAWSTLLRTVYSVLHTTPAILLKEIILVDDASTEEHLKEKLEQYVKQL---QVVRVVRQEERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTVVVSPDIVTIDLNTFEFAKPVQRGRVHSRGNFDWSLTFGWETLPPHEKQRRKDETYPIKSPTFAGGLFSISKSYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGTSVIARNQVRLAEVWMDSYKKIFYRRNLQAAKMAQEKSFGDISERLQLREQLHCHNFSWYLHNVYPEMFVPDLTPTFYGAIKNLGTNQCLDV---GENNRGGKPLIMYSC-HGLGGNQYF-------EYTTQRDLRHNIAKQL-----CLHVSKGALGLGSCHFTGKNSQVPKDEEWELAQDQ-LIRNSGSGTCLTSQDKKP----AMAPCNPSDPHQLW 619          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYS-ESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPG---NKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKN--SKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            ++GPGE G+ V LT ++ +     MKK   N   SD+ISL R +PD R   CK   Y   +LP TSVIIIF +EAW+ LLRT HSV+NRSPP  L+EVIL DD+S +  L   L+ ++K       VR++R  +R GLIRA+L GA+ A G+++VFLDSHCE   GWLEPI+ RI  +R  ++ P+I+SI     +Y+G   +   G F W++HFTW+ + E  +K     TD ++S TMAGGL A++R+YFFE+G YDE M+IWGGENLEISFR WMCGG++E  PCSHVGHIFRA HPY   G   NKD HG NSKR+ +VW+DDYKRL+Y++R +LR  + G+++ R +LR  L CK F WF+ N+   KFI D +++ YG +    S + +C D L ++E  + +   GV+ CQ   SS Q+ SLS            K  N   +RRE  C  A+E NG +   TC  +    + W Y  EN  + NLK  +C+  +NLK  D   +  C+  + +QKW
Sbjct:   72 REGPGEKGKPVVLTGKDAELGQADMKKWFMNVHASDKISLDRDVPDPRIQACKDIKYDYAALPKTSVIIIFTDEAWTPLLRTVHSVINRSPPELLQEVILLDDNSKRQELQEPLDEHIKRF--GGKVRLIRKHVRHGLIRAKLAGAREAVGDIIVFLDSHCEANHGWLEPIVQRISDERTAIVCPMIDSISDNTLAYHGDWSL-STGGFSWALHFTWEGLSEEEQKRRTKPTDYIRSPTMAGGLLAANREYFFEVGGYDEEMDIWGGENLEISFRAWMCGGSIEFIPCSHVGHIFRAGHPYNMTGRNNNKDVHGTNSKRLAEVWMDDYKRLYYMHREDLRTKDVGDLTARHELRKRLNCKPFKWFLDNIAKGKFIMDEDVVAYGALHTVVSGTRMCTDTLQRDE--KMSQLLGVFHCQGKGSSPQLMSLS------------KEGN---LRRENTC--ASEENGNIRMKTCSKKAQFNERWAY--ENKMIRNLKSGKCMSTANLKPGDNAIVVECDEKDEHQKW 571          

Query:  280 NYRANRYHIYNTNQYYQKG----PGENGELV-----SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTD-VGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNS--KSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWE 1884
            N    ++ +   +  Y+KG     GE G+ V      L+ EE    D  M   AFN+  SD IS+ R+LP   ++ECK   Y+E+LP TSVII FHNEAWS LLRT HSV+ R+P   L+EV+L DD S        LE Y+ +Q+    V+I+R + R GLIRARL GA  A GEVL +LDSHCE   GW+EP+L RI +   T++ P+I+ ID   F Y+ S      VG F W + F W  IPE  +K      D V+S TMAGGLF+ D++YF ++G+YD G +IWGGENLE+SF+ WMCGGTLE  PCSHVGH+FR   PY +    +    NS R+ +VWLDDYK  +Y  R   +  + G+IS R KLR  L CKSF W++ N+ PE F+P  ++   G V+NS  +   CLD +V       N   G Y C +G    Q + LS                  +IRR+  C+    ++  V    C   +   Q W YN + G L +   ++CL  +  K+  ++ +  C+  +PYQ W+
Sbjct:   89 NLAKPKFMVDPNDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYM-SQF-GGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYK-TYYYERINNQLGDFGDISSRKKLREDLGCKSFKWYLDNIYPELFVPGESV-AKGEVRNSAVQPARCLDCMVGRH--EKNRPVGTYQC-HGQGGNQYWMLS---------------KDGEIRRDESCVDYAGSD--VMVFPC-HGMKGNQEWRYNHDTGRLQHAVSQKCLGMT--KDGAKLEMVACQYDDPYQHWK 608          

Query:  280 NYRANRYHIYNTNQYYQKG----PGENGELV-----SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTD-VGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNS--KSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWE 1884
            N    ++ +   +  Y+KG     GE G+ V      L+ EE    D  M   AFN+  SD IS+ R+LP   ++ECK   Y+E+LP TSVII FHNEAWS LLRT HSV+ R+P   L+EV+L DD S        LE Y+ +Q+    V+I+R + R GLIRARL GA  A GEVL +LDSHCE   GW+EP+L RI +   T++ P+I+ ID   F Y+ S      VG F W + F W  IPE  +K      D V+S TMAGGLF+ D++YF ++G+YD G +IWGGENLE+SF+ WMCGGTLE  PCSHVGH+FR   PY +    +    NS R+ +VWLDDYK  +Y  R   +  + G+IS R KLR  L CKSF W++ N+ PE F+P  ++   G V+NS  +   CLD +V       N   G Y C +G    Q + LS                  +IRR+  C+    ++  V    C   +   Q W YN + G L +   ++CL  +  K+  ++ +  C+  +PYQ W+
Sbjct:   89 NLAKPKFMVDPNDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYM-SQF-GGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYK-TYYYERINNQLGDFGDISSRKKLREDLGCKSFKWYLDNIYPELFVPGESV-AKGEVRNSAVQPARCLDCMVGRH--EKNRPVGTYQC-HGQGGNQYWMLS---------------KDGEIRRDESCVDYAGSD--VMVFPC-HGMKGNQEWRYNHDTGRLQHAVSQKCLGMT--KDGAKLEMVACQYDDPYQHWK 608          

Query:  280 NYRANRYHIYNTNQYYQKG----PGENGELV-----SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTD-VGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNS--KSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWE 1884
            N    ++ +   +  Y+KG     GE G+ V      L+ EE    D  M   AFN+  SD IS+ R+LP   ++ECK   Y+E+LP TSVII FHNEAWS LLRT HSV+ R+P   L+EV+L DD S        LE Y+ +Q+    V+I+R + R GLIRARL GA  A GEVL +LDSHCE   GW+EP+L RI +   T++ P+I+ ID   F Y+ S      VG F W + F W  IPE  +K      D V+S TMAGGLF+ D++YF ++G+YD G +IWGGENLE+SF+ WMCGGTLE  PCSHVGH+FR   PY +    +    NS R+ +VWLDDYK  +Y  R   +  + G+IS R KLR  L CKSF W++ N+ PE F+P  ++   G V+NS  +   CLD +V       N   G Y C +G    Q + LS                  +IRR+  C+    ++  V    C   +   Q W YN + G L +   ++CL  +  K+  ++ +  C+  +PYQ W+
Sbjct:   89 NLAKPKFMVDPNDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYM-SQF-GGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYK-TYYYERINNQLGDFGDISSRKKLREDLGCKSFKWYLDNIYPELFVPGESV-AKGEVRNSAVQPARCLDCMVGRH--EKNRPVGTYQC-HGQGGNQYWMLS---------------KDGEIRRDESCVDYAGSD--VMVFPC-HGMKGNQEWRYNHDTGRLQHAVSQKCLGMT--KDGAKLEMVACQYDDPYQHWK 608          

Query:  280 NYRANRYHIYNTNQYYQKG----PGENGELV-----SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTD-VGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWE 1884
            N    ++ +   +  Y+KG     GE G+ V      L+ EE    D  M   AFN+  SD IS+ R+LP   ++ECK   Y+E+LP TSVII FHNEAWS LLRT HSV+ R+P   L+EV+L DD S        LE Y+ +Q+    V+I+R + R GLIRARL GA  A GEVL +LDSHCE   GW+EP+L RI +   T++ P+I+ ID   F Y+ S      VG F W + F W  IPE  +K      D V+S TMAGGLF+ D++YF ++G+YD G +IWGGENLE+SF+ WMCGGTLE  PCSHVGH+FR   PY +    +    NS R+ +VWLDDYK  +Y  R   +  + G+IS R KLR  L CKSF W++ N+ PE F+P  ++   G ++N++++ CLD  V  E +  N     Y C     + Q + LS                  +IRR+  C+    ++  V    C   +   Q W YN + G L +   ++CL  +  K+  ++ +  C+  +PYQ W+
Sbjct:   89 NLAKPKFMVDPNDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYM-SQF-GGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYK-TYYYERINNQLGDFGDISSRKKLREDLGCKSFKWYLDNIYPELFVPGESV-AKGELRNAQTSQCLDSAVGEEVE--NKAITPYPCHEQGGN-QYWMLS---------------KDGEIRRDESCVDYAGSD--VMVFPC-HGMKGNQEWRYNHDTGRLQHAVSQKCLGMT--KDGAKLEMVACQYDDPYQHWK 606          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSEC-KAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSY-YGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVK------SATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELR-EANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNG---KVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q  + G GE G  V L+    +  D++ KK A N   S++++  RS+ D RN  C K    S+SLPT SV+IIF NE +S LLRT HS ++    + LKE+IL DD S  V LG +L+ YV+T+ P   V I+R K RLGLIRARL GA+ A G+VL+FLD+HCE   GW EP+L RI + R +++VPII+ IDA  F Y        QVG F W+ HF W ++PE  K+  + +    +      S TMAGGLFA DR+YF+E+GSYDE M+ WGGENLE+SFR W CGGT+ET PCS VGHIFR  HPY FP ++D HG+N+ RM  VW+D+Y  +F+L RP+L+  A+ G+++ R+ LR  L+CKSF+W++KN+ PEKF+P +++ G+G V    SN+CLD L+QN  +    + G+Y C      +Q+FS +               N   +R E  C T   +     +V  + C+      + W Y  E+  +++     CLD   LK++D   + PC+  +  Q+W
Sbjct:   84 QKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQN--NEKPYNAGLYPCGKVLQKSQLFSFT---------------NTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCLDHQGLKSLDDAQVAPCDPHSESQRW 597          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSEC-KAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSY-YGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVK------SATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELR-EANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNG---KVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q  + G GE G  V L+    +  D++ KK A N   S++++  RS+ D RN  C K    S+SLPT SV+IIF NE +S LLRT HS ++    + LKE+IL DD S  V LG +L+ YV+T+ P   V I+R K RLGLIRARL GA+ A G+VL+FLD+HCE   GW EP+L RI + R +++VPII+ IDA  F Y        QVG F W+ HF W ++PE  K+  + +    +      S TMAGGLFA DR+YF+E+GSYDE M+ WGGENLE+SFR W CGGT+ET PCS VGHIFR  HPY FP ++D HG+N+ RM  VW+D+Y  +F+L RP+L+  A+ G+++ R+ LR  L+CKSF+W++KN+ PEKF+P +++ G+G V    SN+CLD L+QN  +    + G+Y C      +Q+FS +               N   +R E  C T   +     +V  + C+      + W Y  E+  +++     CLD   LK++D   + PC+  +  Q+W
Sbjct:   84 QKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQN--NEKPYNAGLYPCGKVLQKSQLFSFT---------------NTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCLDHQGLKSLDDAQVAPCDPHSESQRW 597          

Query:  259 GINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIP-EHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGN-KDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGY---GYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW--ESQF 1893
            GI+++  +    ++ +  + Q  +  PGE G+ V +  +    + +  K+  FN   SD ISL RSL D R+  C+   Y+  LPTTS++I+FHNEAW+ LLRT  SV+NRSP   LKE+IL DD+S +  LG +LE YV  + P     ++R++ R GLIRARL GA+   GEV+ FLD+HCE T GWLEP+L RI Q R T++ PII+ I  + F Y  ++D    G F W ++F W  +P     +    +T  +++ TMAGGLF+ D+ YF+EIGSYDEGM+IWGGENLE+SFR WMCGG LE  PCS VGH+FR + PYTFPG   +    N+ R+V+VWLDD+K  +Y + P  R+A+AG++S R  LR+ L+CKSF W+++NV PE  +P    L Y   G ++N+++  CLD + +    + N   G+  C +G    Q+F+ +  +  +SD+                CL A+ +NG V+ + C   +   Q W+Y+ E   + +    QCL  +   + +   ++PC S    Q+W  ES+F
Sbjct:  103 GISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYV-AKLPVKTF-VLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASD-STWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMP----LDYYYLGEIRNAETETCLDTMGR----KYNEKVGISYC-HGLGGNQVFAYTKRQQIMSDDL---------------CLDASSSNGPVNMVRC-HNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPC-SYGKGQQWLMESKF 625          

Query:  259 GINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIP-EHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGL-NSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGY---GYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW--ESQF 1893
            GI+++  +    ++ +  + Q  +  PGE G+ V +  +    + +  K+  FN   SD ISL RSL D R+  C+   Y+  LPTTS++I+FHNEAW+ LLRT  SV+NRSP   LKE+IL DD+S +  LG +LE YV  + P     ++R++ R GLIRARL GA+   GEV+ FLD+HCE T GWLEP+L RI Q R T++ PII+ I  + F Y  ++D    G F W ++F W  +P     +    +T  +++ TMAGGLF+ D+ YF+EIGSYDEGM+IWGGENLE+SFR W CGG LE  PCSHVGH+FR   PYTFPG      L N+ R+ +VWLD+++  +Y      R+A+AG++S R  LR+ L+CKSF W+++NV PE  +P    L Y   G ++N+++  CLD + +    + N   G+  C +G    Q+F+ +  +  +SD+                CL A+ +NG V+ + C   +   Q W+Y+ E   + +    QCL  +   + +   ++PC S    Q+W  ES+F
Sbjct:  103 GISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYV-AKLPVKTF-VLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASD-STWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMP----LDYYYLGEIRNAETETCLDTMGR----KYNEKVGISYC-HGLGGNQVFAYTKRQQIMSDDL---------------CLDASSSNGPVNMVRC-HNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPC-SYGKGQQWLMESKF 625          

Query:  325 YQKGPGENGELVSL----TDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECK-AFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVG-QVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            +++ PGE G+ V L    +DE  K +DD   K AFN+  SD IS+ R+LPD R++ CK    Y  +LP T VII FHNEAW+ LLRT HSV++RSP   + ++IL DD S    L  +LE Y    +P   V+I+R + R GLIRAR+ GA  A   VL +LDSHCE T GWLEP+L RI +   T++ P+I+ I  +   Y+     G  VG F W++ F+W  +PE  +K      + V S TMAGGLF+ DR++F  +G+YD G +IWGGENLE+SF+TWMCGGTLE  PCSHVGHIFR   PY +    +    NS R+ +VW+D+Y + +Y +R    + + G++S R KLRN L+CKSF W++ N+ PE FIP  ++  +G + N  + +CLD   ++E +       +Y C +G    Q + LS            KA    +IRR+  CL     +  V    C       Q W Y +    L +    +CL  S  K  D++ ++ C +S   Q+W
Sbjct:  142 FEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYF-AAYPK--VQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEYSQ-YYYHRIGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSV-AHGEIANVPNGMCLDAKEKSEEE---TPVSIYEC-HGQGGNQYWMLS------------KAG---EIRRDDSCLDYAGKD--VTLFGCHGGK-GNQFWTYRENTKQLHHGTSGKCLAISESK--DKLLMEECSASLSRQQW 637          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYV-KTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q    GPGE G+ V +  ++ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAW+ LLRT HSV++RSP   L+E++L DD+S +  L  +LE YV K + P   VR+VR + R GLIRARL+GA  + G+V+ FLD+HCE TTGWLEP+L RI   ++T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R  LR  LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    SL+++   QCLD ++  +    +++ C  +   Q+W
Sbjct:   50 QRPHDGPGEMGKPVVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVP---VRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVMMLKC-HHLKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSGARS-QQW 546          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYV-KTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q    GPGE G+ V +  ++ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAW+ LLRT HSV++RSP   L+E++L DD+S +  L  +LE YV K + P   VR+VR + R GLIRARL+GA  + G+V+ FLD+HCE TTGWLEP+L RI   ++T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R  LR  LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    SL+++   QCLD ++  +    +++ C  +   Q+W
Sbjct:   50 QRPHDGPGEMGKPVVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVP---VRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVMMLKC-HHLKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSGARS-QQW 546          

Query:  154 ILFGIFLITHNKFKISDSKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            +L  +FL+ +       S+ N   N KD S L AL   +S       R H         + PGE G+ V +  EE   + ++ K   FN   SD I+L RSLPD R   CK   Y + LP TS++I+FHNEAWS LLRT HS +NRSP + L E++L DD+S +  L  +LE YV T   +  VRI+R + R GLIRARL GA A  G+V+ FLD+HCE TTGWLEP++ RI + R  ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR SL+CK F W+++NV P+  IP R     G ++N ++N C+D + + E    N   G ++C +G    Q+FS +  K               +IR +  CL A+  NG V  + C   +   Q++ Y+ E  +L+++   QCLD  + ++    T++ C S    Q+W
Sbjct:   18 VLVDVFLLLYF------SECNKCDNRKDHSLLPALRAVMS-------RAH---------EAPGEMGKAVVIPKEEQDKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKTYPDDLPNTSIVIVFHNEAWSTLLRTVHSAINRSPRQLLYEILLVDDASERDFLKEKLEDYVATL--EVPVRILRMEQRTGLIRARLRGAAATRGQVITFLDAHCECTTGWLEPLMARIKEDRRAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRTYFEEIGTYDSGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVVRVDYGDVSSRKALRESLKCKPFSWYLENVYPDSQIP-RRYYSLGEIRNVETNQCVDNMGRKE----NEKVGFFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDASRLNGPVVMLKC-HHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLKDC-SGRRSQQW 547          

Query:  154 ILFGIFLITHNKFKISDSKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITC 1722
            +L  +FL+ +       S+ N   N KD S L AL   +S       R H         + PGE G+ V +  EE   + ++ K   FN   SD I+L RSLPD R   CK   Y + LP TS++I+FHNEAWS LLRT HS +NRSP + L E++L DD+S +  L  +LE YV T   +  VRI+R + R GLIRARL GA A  G+V+ FLD+HCE TTGWLEP++ RI + R  ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR SL+CK F W+++NV P+  IP R     G ++N ++N C+D + + E    N   G ++C +G    Q+FS +  K               +IR +  CL A+  NG V  + C
Sbjct:   18 VLVDVFLLLYF------SECNKCDNRKDHSLLPALRAVMS-------RAH---------EAPGEMGKAVVIPKEEQDKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKTYPDDLPNTSIVIVFHNEAWSTLLRTVHSAINRSPRQLLYEILLVDDASERDFLKEKLEDYVATL--EVPVRILRMEQRTGLIRARLRGAAATRGQVITFLDAHCECTTGWLEPLMARIKEDRRAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRTYFEEIGTYDSGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVVRVDYGDVSSRKALRESLKCKPFSWYLENVYPDSQIP-RRYYSLGEIRNVETNQCVDNMGRKE----NEKVGFFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDASRLNGPVVMLKC 496          

Query:  334 GPGENGELV---SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSL-PDFRNSEC--KAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQ---VGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPE----LREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLS---PVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVT---ELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
             PG +G+     +L+  E K  +   +K  FN   SDRISL R L PD R  EC  + F     LPTTSVII+FHNEAWS LLRT +SV++ SP  FLKE+IL DD+S    L  +L+ ++K     ++VR+VR   R GLI ARL GA  A G+ L FLD+HCE   GWLEP+L RI +    ++ P I +ID   F +   +  GQ    G F W + F W+ +P+H ++  K +T  +K+ T AGGLF+  R YF+ IGSYDE MEIWGGEN+E+SFR W CGG LE  PCS VGH+FR   P+TFP        N  R+ +VW+DDYK +FY    +     +E + G++S R+ LR  LQCKSF W++KNV PE F+PD N L +G ++N     CLD+   NE   G     +Y C +G    Q F  S    ++++I     +   +   +R E  C     N      IT      EL E QL+ YNK +        KQCL A      +  ++ PC   + YQ W
Sbjct:  114 APGASGKAFHTDNLSSSEQKEKERGEEKHCFNLYASDRISLSRDLGPDTRPPECIEQTFRRCPPLPTTSVIIVFHNEAWSTLLRTVYSVLHTSPALFLKEIILVDDASVDEHLKDKLDEFLKQL---HIVRVVRQHERKGLITARLLGASVATGDTLTFLDAHCECFHGWLEPLLARIAENSSAVVSPDITTIDLNTFEFMKPSPYGQHHNRGNFDWGLSFGWETLPDHERRRRKDETYPIKTPTFAGGLFSISRDYFYHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGTQVIARNQVRLAEVWMDDYKEIFYRRNQQAAQIAKEHSFGDVSRRVDLRERLQCKSFSWYLKNVYPEVFMPDLNPLQFGAIRNMGKEACLDVGESNE---GGKPLIMYPC-HGMGGNQYFEYSTHHEIRHNIQKELCLDGTDGAMVRLE-ECQYKGHNT-----ITSPQQKWELREDQLF-YNKAS--------KQCLSA----RPENPSLVPCNPDDKYQLW 622          

Query:  310 NTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            + NQ   +GPGE G+ V +  EE + + ++ K   FN   S+ I+L RSLPD R   CK  +Y +SLPTTSV+I+FHNEAW+ LLRT HSV+NRSP   L+E+IL DD+S +  L   LE YVK       V ++R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L+++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   48 DINQKPHEGPGEMGKPVVIPKEEQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLQEIILVDDASEREFLKRPLETYVKKL--TVPVHVLRMEQRSGLIRARLRGAAASKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRRGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRVGLRHKLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTASK---------------EIRTDDLCLDVSKLNGPVIMLKC-HHLRGNQLWEYDPVKLTLVHVNSNQCLDKAAEEDSQVPSIRDCSGSRS-QQW 547          

Query:  310 NTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            + NQ   +GPGE G+ V +  EE + + ++ K   FN   S+ I+L RSLPD R   CK  +Y +SLPTTSV+I+FHNEAW+ LLRT HSV+NRSP   L+E+IL DD+S +  L   LE YVK       V ++R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L+++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   49 DINQKPHEGPGEMGKPVVIPKEEQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLQEIILVDDASEREFLKRPLETYVKKL--TVPVHVLRMEQRSGLIRARLRGAAASKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRRGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRVGLRHKLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTASK---------------EIRTDDLCLDVSKLNGPVIMLKC-HHLRGNQLWEYDPVKLTLVHVNSNQCLDKAAEEDSQVPSIRDCSGSRS-QQW 548          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
             +GPGE G+ V +  EE + + ++ K   FN   S+ I+L RSLPD R   CK  +Y +SLPTTSV+I+FHNEAW+ LLRT HSV+NRSP   L+E+IL DD+S +  L   LE YVK       V ++R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L+++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   50 HEGPGEMGKPVVIPKEEQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLQEIILVDDASEREFLKRPLETYVKKL--TVPVHVLRMEQRSGLIRARLRGAAASKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRRGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRVGLRHKLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTASK---------------EIRTDDLCLDVSKLNGPVIMLKC-HHLRGNQLWEYDPVKLTLVHVNSNQCLDKAAEEDSQVPSIRDCSGSRS-QQW 543          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
             +GPGE G+ V +  EE + + ++ K   FN   S+ I+L RSLPD R   CK  +Y +SLPTTSV+I+FHNEAW+ LLRT HSV+NRSP   L+E+IL DD+S +  L   LE YVK       V ++R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L+++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   57 HEGPGEMGKPVVIPKEEQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLQEIILVDDASEREFLKRPLETYVKKL--TVPVHVLRMEQRSGLIRARLRGAAASKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRRGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRVGLRHKLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTASK---------------EIRTDDLCLDVSKLNGPVIMLKC-HHLRGNQLWEYDPVKLTLVHVNSNQCLDKAAEEDSQVPSIRDCSGSRS-QQW 550          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
             +GPGE G+ V +  EE + + ++ K   FN   S+ I+L RSLPD R   CK  +Y +SLPTTSV+I+FHNEAW+ LLRT HSV+NRSP   L+E+IL DD+S +  L   LE YVK       V ++R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L+++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   57 HEGPGEMGKPVVIPKEEQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLQEIILVDDASEREFLKRPLETYVKKL--TVPVHVLRMEQRSGLIRARLRGAAASKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRRGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRVGLRHKLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTASK---------------EIRTDDLCLDVSKLNGPVIMLKC-HHLRGNQLWEYDPVKLTLVHVNSNQCLDKAAEEDSQVPSIRDCSGSRS-QQW 550          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKT-QWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q   +GPGE G+ V +  E+ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y ++LPTTSV+I+FHNEAWS LLRT HSV+NRSP   ++E++L DD+S +  L   LE+YVK  + P   V ++R + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR  LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L ++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   52 QKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVP---VHVIRMEQRSGLIRARLKGAAVSRGQVITFLDAHCECTAGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRRKLQCKPFSWYLENIYPDSQIP-RHYFSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVTMLKC-HHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRS-QQW 548          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKT-QWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q   +GPGE G+ V +  E+ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y ++LPTTSV+I+FHNEAWS LLRT HSV+NRSP   ++E++L DD+S +  L   LE+YVK  + P   V ++R + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR  LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L ++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   52 QKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVP---VHVIRMEQRSGLIRARLKGAAVSRGQVITFLDAHCECTAGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRRKLQCKPFSWYLENIYPDSQIP-RHYFSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVTMLKC-HHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRS-QQW 548          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKT-QWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q   +GPGE G+ V +  E+ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y ++LPTTSV+I+FHNEAWS LLRT HSV+NRSP   ++E++L DD+S +  L   LE+YVK  + P   V ++R + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR  LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L ++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   52 QKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVP---VHVIRMEQRSGLIRARLKGAAVSRGQVITFLDAHCECTAGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRRKLQCKPFSWYLENIYPDSQIP-RHYFSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVTMLKC-HHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRS-QQW 548          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYH-GLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q+GPGE G+ V +  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAWS LLRT +SV+NRSP   L EVIL DD+S +  L   LE YVKT   +  V+I+R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI + R+T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PYTFPG   +    N++R+ +VW+D++K  FY+  P + + + G++S R  LR +L+CK F W+++N+ P+  IP R     G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  +  +G V  + C   +   QLW Y+ E  +L +    QCLD  + ++    T+Q C  S   Q+W
Sbjct:   54 QEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTL--EVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIP-RRYYSLGEIRNVETNQCLDNMGRKE----NEKVGIFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLSGPVIMLKC-HHMRGNQLWEYDAERLTLRHANSNQCLDEPSEEDKMVPTMQDCSGSRS-QQW 547          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYH-GLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q+GPGE G+ V +  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAWS LLRT +SV+NRSP   L EVIL DD+S +  L   LE YVKT   +  V+I+R + R GLIRARL GA A+ G+V+ FLD+HCE T GWLEP+L RI + R+T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PYTFPG   +    N++R+ +VW+D++K  FY+  P + + + G++S R  LR +L+CK F W+++N+ P+  IP R     G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  +  +G V  + C   +   QLW Y+ E  +L +    QCLD  + ++    T+Q C  S   Q+W
Sbjct:   54 QEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTL--EVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIP-RRYYSLGEIRNVETNQCLDNMGRKE----NEKVGIFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLSGPVIMLKC-HHMRGNQLWEYDAERLTLRHANSNQCLDEPSEEDKMVPTMQDCSGSRS-QQW 547          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYS-ESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPG---NKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKN--SKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            ++GPGE G+ V LT ++ +     MKK   N   SD+ISL R +PD R   CK   Y   +LP TSVIIIF +EAW+ LLRT HSV+NRSPP  L+EVIL DD+S +  L   L+ ++K       VR++R  +R GLIRA+L GA+ A G+++VFLDSHCE   GWLEPI+ RI  +R  ++ P+I+SI     +Y+G   +   G F W++HFTW+ + E  +K     TD ++S TMAGGL A++R+YFFE+G YDE M+IWGGENLEISFR WMCGG++E  PCSHVGHIFRA HPY   G   NKD HG NSKR+ +VW+DDYKRL+Y++R +LR  + G+++ R +LR  L CK F WF+ N+   KFI D +++ YG +    S + +C D L ++E  + +   GV+ CQ   SS Q+ SLS            K  N   +RRE  C  A+E NG +   TC  +    + W Y  EN  + NLK  +C+  +NLK  D   +  C+  + +QKW
Sbjct:   72 REGPGEKGKPVVLTGKDAELGQADMKKWFMNVHASDKISLDRDVPDPRIQACKDIKYDYAALPKTSVIIIFTDEAWTPLLRTVHSVINRSPPELLQEVILLDDNSKRQELQEPLDEHIKRF--GGKVRLIRKHVRHGLIRAKLAGAREAVGDIIVFLDSHCEANHGWLEPIVQRISDERTAIVCPMIDSISDNTLAYHGDWSL-STGGFSWALHFTWEGLSEEEQKRRTKPTDYIRSPTMAGGLLAANREYFFEVGGYDEEMDIWGGENLEISFRAWMCGGSIEFIPCSHVGHIFRAGHPYNMTGRNNNKDVHGTNSKRLAEVWMDDYKRLYYMHREDLRTKDVGDLTARHELRKRLNCKPFKWFLDNIAKGKFIMDEDVVAYGALHTVVSGTRMCTDTLQRDE--KMSQLLGVFHCQGKGSSPQLMSLS------------KEGN---LRRENTC--ASEENGNIRMKTCSKKAQFNERWAY--ENKMIRNLKSGKCMSTANLKPGDNAIVVECDEKDEHQKW 571          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSEC-KAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSY-YGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVK------SATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELR-EANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNG---KVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q  + G GE G  V L+    +  D++ KK A N   S++++  RS+ D RN  C K    S+SLPT SV+IIF NE +S LLRT HS ++    + LKE+IL DD S  V LG +L+ YV+T+ P   V I+R K RLGLIRARL GA+ A G+VL+FLD+HCE   GW EP+L RI + R +++VPII+ IDA  F Y        QVG F W+ HF W ++PE  K+  + +    +      S TMAGGLFA DR+YF+E+GSYDE M+ WGGENLE+SFR W CGGT+ET PCS VGHIFR  HPY FP ++D HG+N+ RM  VW+D+Y  +F+L RP+L+  A+ G+++ R+ LR  L+CKSF+W++KN+ PEKF+P +++ G+G V    SN+CLD L+QN  +    + G+Y C      +Q+FS +               N   +R E  C T   +     +V  + C+      + W Y  E+  +++     CLD   LK++D   + PC+  +  Q+W
Sbjct:   84 QKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQN--NEKPYNAGLYPCGKVLQKSQLFSFT---------------NTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCLDHQGLKSLDDAQVAPCDPHSESQRW 597          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKT-QWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q   +GPGE G+ V +  E+ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y ++LPTTSV+I+FHNEAWS LLRT HSV+NRSP   ++E++L DD+S +  L   LE+YVK  + P   V ++R + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L ++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   52 QKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVP---VHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIP-RHYFSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVTMLKC-HHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGSRS-QQW 548          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKT-QWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q   +GPGE G+ V +  E+ + + ++ K   FN   S+ I+L RSLPD R   CK  +Y ++LPTTSV+I+FHNEAWS LLRT HSV+NRSP   L+E++L DD+S +  L   LE+YVK  + P   V ++R + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI   R+T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQC+ F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L ++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   52 QKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMLEEIVLVDDASERDFLKRPLESYVKKLKVP---VHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRHKLQCRPFSWYLENIYPDSQIP-RHYFSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVTMLKC-HHLKGNQLWEYDPVKLTLQHVNSNQCLDKATDEDSQVPSIRDCSGSRS-QQW 548          

Query:  319 QYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKT-QWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Q   +GPGE G+ V +  E+ + + ++ K   FN   S+ I+  RSLPD R   CK  +Y +SLPTTSV+I+FHNEAWS LLRT HSV+NRSP   ++E++L DD+S +  L   LE+YVK  + P   V ++R + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI   R T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R+ LR+ LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L ++   QCLD +  ++    +I+ C  S   Q+W
Sbjct:   52 QKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIAFNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVP---VHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIP-RHYFSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVTMLKC-HHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRS-QQW 548          

Query:  241 SFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNL--DDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPEL--REANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPD--RNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIET-----QLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWE 1884
            S    L +    Y  R  R+  Y  ++ +++GPGE G  V LT +E   L  D +  KEAFNR +SDRISL RSL D R  EC++  Y   LPT SV+IIFH EAWS+L+RT HSVVNR+PPR+LKEV+L DD S K  L   L+ Y+   +PD VVR+VRS+ RLGLIRARLEGAKAA G+V+ FLDSHCE T GW EP+L RI + R  ++ PIIES+ A   SY G      VG+FWWS HFTW  IPEH  +  +  TD ++SATMAGGLFA DR+YFFE+G+YDEGM IWGGENLEISFR WMCGGTLE  PCS VGHIFRA+HPY+FPG+KDYHGLN+ R+VDVW+D+YKRLFY++R +L  R A+ G++S R+ LR  L CK F W+++NV+PEKFIPD  R++  YG ++N  +N+C+DLL  NEFDR     G+YSCQ GAS  QIFS S  +               +IRREWGCL A   + +V FITC T + +      Q W  + +  ++ +    +CL A  +KN +   +  C ++NP+Q WE
Sbjct:   58 SICRQLDVTPDVYQARLRRFTEYQKSEPFRQGPGEQGHGVYLTADEKNRLGYDAMFTKEAFNRISSDRISLDRSLNDMRAMECRSISYPADLPTLSVVIIFHEEAWSSLMRTVHSVVNRTPPRYLKEVVLLDDFSTKEHLLRNLDNYLARTFPDGVVRVVRSRERLGLIRARLEGAKAATGDVVAFLDSHCEATKGWAEPLLARIKESRSAVLCPIIESVSADSLSYNGGGSSYSVGSFWWSGHFTWDMIPEHELRRRQKHTDPIRSATMAGGLFAVDRKYFFEVGAYDEGMGIWGGENLEISFRVWMCGGTLEFIPCSRVGHIFRASHPYSFPGHKDYHGLNTMRLVDVWMDEYKRLFYMHRHDLVSRTADRGDVSSRVALRKRLNCKPFSWYLENVIPEKFIPDSTRDVTAYGMLRNPITNMCVDLLNYNEFDRNPTAAGLYSCQGGASGRQIFSYSRKQ---------------EIRREWGCLQAGPGSDRVSFITCTTRVTDPEAGAGQRWQLDPQAKTIRHSASGRCLSAEGVKNGEAAKLSDCSATNPHQVWE 601          

Query:  241 SFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNL--DDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPEL--REANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPD--RNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIET-----QLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWE 1884
            S    L +    Y  R  R+  Y  ++ +++GPGE G  V LT +E   L  D +  KEAFNR +SDRISL RSL D R  EC++  Y   LPT SV+IIFH EAWS+L+RT HSVVNR+PPR+LKEV+L DD S K  L   L+ Y+   +PD VVR+VRS+ RLGLIRARLEGAKAA G+V+ FLDSHCE T GW EP+L RI + R  ++ PIIES+ A   SY G      VG+FWWS HFTW  IPEH  +  +  TD ++SATMAGGLFA DR+YFFE+G+YDEGM IWGGENLEISFR WMCGGTLE  PCS VGHIFRA+HPY+FPG+KDYHGLN+ R+VDVW+D+YKRLFY++R +L  R A+ G++S R+ LR  L CK F W+++NV+PEKFIPD  R++  YG ++N  +N+C+DLL  NEFDR     G+YSCQ GAS  QIFS S  +               +IRREWGCL A   + +V FITC T + +      Q W  + +  ++ +    +CL A  +KN +   +  C ++NP+Q WE
Sbjct:   55 SICRQLDVTPDVYQVRLRRFTEYQKSEPFRQGPGEQGHGVYLTADEKNRLGYDAMFAKEAFNRISSDRISLDRSLNDMRAMECRSISYPADLPTLSVVIIFHEEAWSSLMRTVHSVVNRTPPRYLKEVVLLDDFSTKEHLLRNLDNYLARTFPDGVVRVVRSRERLGLIRARLEGAKAATGDVVAFLDSHCEATKGWAEPLLARIKESRSAVLCPIIESVSADSLSYNGGGSSYSVGSFWWSGHFTWDMIPEHELRRRQKHTDPIRSATMAGGLFAVDRKYFFEVGAYDEGMGIWGGENLEISFRVWMCGGTLEFIPCSRVGHIFRASHPYSFPGHKDYHGLNTMRLVDVWMDEYKRLFYMHRHDLVSRTADRGDVSSRVALRKRLNCKPFSWYLENVIPEKFIPDSTRDVTAYGMLRNPITNMCVDLLNYNEFDRNPTAAGLYSCQGGASGRQIFSYSRKQ---------------EIRREWGCLQAGPGSDRVSFITCTTRVTDPEAGAGQRWQLDPQAKTIRHNASGRCLSAEGVKNGEAAKLSDCSATNPHQVWE 598          

Query:  241 SFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNL--DDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPEL--REANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPD--RNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIET-----QLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQ 1875
            S    L +    Y  R  R+  Y  ++ +++GPGE G  V LT +E   L  D +  KEAFNR +SDRISL RSL D R  EC++  Y   LPT SV+IIFH EAWS+L+RT HSVVNR+PPR+LKEV+L DD S K  L   L+ Y+   +PD VVR+VRS+ RLGLIRARLEGAKAA G+V+ FLDSHCE T GW EP+L RI + R  ++ PIIES+ A   SY G      VG+FWWS HFTW  IPEH  +  +  TD ++SATMAGGLFA DR+YFFE+G+YDEGM IWGGENLEISFR WMCGGTLE  PCS VGHIFRA+HPY+FPG+KDYHGLN+ R+VDVW+D+YKRLFY++R +L  R A+ G++S R+ LR  L CK F W+++NV+PEKFIPD  R++  YG ++N  +N+C+DLL  NEFDR     G+YSCQ GAS  QIFS S  +               +IRREWGCL A   + +V FITC T + +      Q W  + +  ++ +    +CL A  +KN +   +  C ++NP+Q
Sbjct:  729 SICRQLDVTPDVYQVRLRRFTEYQKSEPFRQGPGEQGHGVYLTADEKNRLGYDAMFAKEAFNRISSDRISLDRSLNDMRAMECRSISYPADLPTLSVVIIFHEEAWSSLMRTVHSVVNRTPPRYLKEVVLLDDFSTKEHLLRNLDNYLARTFPDGVVRVVRSRERLGLIRARLEGAKAATGDVVAFLDSHCEATKGWAEPLLARIKESRSAVLCPIIESVSADSLSYNGGGSSYSVGSFWWSGHFTWDMIPEHELRRRQKHTDPIRSATMAGGLFAVDRKYFFEVGAYDEGMGIWGGENLEISFRVWMCGGTLEFIPCSRVGHIFRASHPYSFPGHKDYHGLNTMRLVDVWMDEYKRLFYMHRHDLVSRTADRGDVSSRVALRKRLNCKPFSWYLENVIPEKFIPDSTRDVTAYGMLRNPITNMCVDLLNYNEFDRNPTAAGLYSCQGGASGRQIFSYSRKQ---------------EIRREWGCLQAGPGSDRVSFITCTTRVTDPEAGAGQRWQLDPQAKTIRHNASGRCLSAEGVKNGEAAKLSDCSATNPHQ 1269          

Query:  286 RANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTAT-ENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            R  R+  Y  ++  +KGPGENGE V L  EE      + KKEAFN   SD+ISLQRS+ D R+S+CK   Y + LP+ SV+IIFHNEAWS LLRTAHSVVNRSPP +L EVIL DD S +  LG +L  YV   WPD VVRIVR+  R GLIRARL GA AA G+VL+FLDSHCE + GWLEP+L RI++    M+ P I+ ID K    YG T    VG FWWS+HF+W+ IP+H K+  K   D ++S TMAGGLFA DR++FF+IG+YD GME+WGGENLEISFR WMCGG LE  PCS VGHIFRA+HPYTFPGNKD HGLNS R+ +VW+D+YKRLFY +R +L   + G+IS R  LR  L+CK+F W++ NV PEKFIPD N+  +G V+N  SNLCLD L ++E  +     G++SCQNGAS++++FSLS                  ++RRE GC+    ++ G    + C       Q W ++K  G++++ +   CLD   +++     +  C ++   QKW
Sbjct:   49 RRKRFEDYQVSESSRKGPGENGEPVILEREEKALAASLFKKEAFNIIASDKISLQRSVKDVRDSKCKDIQYPKKLPSASVVIIFHNEAWSPLLRTAHSVVNRSPPEYLHEVILLDDFSDRPELGEKLNKYVDETWPDGVVRIVRTMERSGLIRARLAGAVAAKGDVLIFLDSHCEASAGWLEPLLGRINEDPTAMLCPEIDLID-KDTLQYGGTGSYSVGGFWWSLHFSWRPIPKHEKERRKSDVDPIRSPTMAGGLFAVDREFFFKIGAYDNGMEVWGGENLEISFRVWMCGGKLEFIPCSRVGHIFRASHPYTFPGNKDTHGLNSMRLAEVWMDEYKRLFYSHRRDLLGQDYGDISERKALREKLKCKNFKWYLDNVYPEKFIPDENVHAWGMVRNPSSNLCLDTLGKDE--KMTFDVGLFSCQNGASASEVFSLSMEN---------------ELRREEGCMAYNGKSGGHPHLVNCNG--AANQKWKHDKNTGTIIHTESGLCLDREKVESGGYSMVITCVANKDSQKW 561          

Query:  307 YNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNG-KVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Y     +++GPGE G  V L  EE KN D++ KKEAFN   SD I+L RSLPD RN  CK+  Y + LPT SV+IIFHNEAW+ LLRTAHSVVNRSPP++L EVIL DD+SY+  LG EL+ YV+  WPD VV++VR K R GLIRAR+ GAKAA G+VL+FLDSHCE   GWLEP+L RI +K + ++VP I+ I ++   Y   T  G VG FWWS+HF+W+ +P+      K + D V+S TM GGLFA+DR+YFF++G+YD GM++WGGENLEISFR WMCGG+LE  PCS VGHIFR++HPYTFPGNKD HG+NS R+ +VW+D+YKRLFY++R +L + + G+IS R  LR  L+CKSF W+++NV PEKFI D  +L YG V+N  SNLCLD + ++E  R ++  G++ CQNGAS+ ++FSLS                  ++RRE  CL +    G KV    C       Q W ++K++G ++++   +CLD S LK+ D V ++ C   N  QKW
Sbjct:   60 YENRNRHKQGPGEYGAGVFLQGEEKKNADELAKKEAFNIIASDGIALDRSLPDVRNPACKSVEYPKDLPTASVVIIFHNEAWTPLLRTAHSVVNRSPPQYLHEVILLDDASYRDRLGEELDKYVQDTWPDGVVKVVRVKERAGLIRARIAGAKAATGDVLIFLDSHCEANEGWLEPLLARIKEKTDAVLVPDIDMISSETLQYI-PTGSGSVGGFWWSLHFSWRPMPKREAVRRKSEIDPVRSPTMPGGLFAADRKYFFDVGAYDPGMDVWGGENLEISFRVWMCGGSLEFIPCSRVGHIFRSSHPYTFPGNKDTHGINSMRLAEVWMDEYKRLFYMHRRDLLKQDMGDISERKALRERLKCKSFSWYLENVYPEKFIIDEKVLAYGMVRNPGSNLCLDTMGKDEKTRFDI--GLFHCQNGASANEVFSLS---------------QKNELRREEACLDSVGAEGSKVSLNPCHGHK-GNQEWRHHKDSGVIVHVPSGKCLDVSGLKSGDSVQLKKCNGGND-QKW 565          

Query:  334 GPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYV-KTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            GPGE G+ V +  E+++ + ++ K   FN   S+ I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAW+ LLRT HSV+NRSP   L+EV+L DD+S +  L  +LE YV K + P   VRIVR + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI Q ++T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+I+ R  LR  LQCK F W+++NV P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    SL+++   QCLD ++  +    +++ C  S   Q+W
Sbjct:   55 GPGEMGKPVVIPKEQHEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKNKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLEEVVLVDDASERDFLKRKLEQYVRKLEVP---VRIVRMEQRSGLIRARLKGASLSTGQVITFLDAHCECTMGWLEPLLSRIKQDKKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDIATRASLRQKLQCKPFSWYLENVYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVMMLKC-HHLKGNQLWDYDPLKLSLVHVNSNQCLDKASEDDSQVPSVRDCTGSRS-QQW 546          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMD-RVTIQPCESSNPYQKW 1881
             +GPGE G+ V +  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y + LP TS++I+FHNEAWS LLRT HSV+NRSP   L E++L DD+S +  L  +LE YVKT   +  VRI+R + R GLIRARL GA A  G+V+ FLD+HCE T GWLEP+L RI + R+ ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR +LQCK F W+++N+ P+  IP R     G ++N ++N C+D + + E    N   G ++C +G    Q+FS +  K               +IR +  CL  +  NG V  + C   +   Q++ Y+ E G+ M++  + CL  S L++     T++ C+ S P Q W
Sbjct:   54 HEGPGEMGKAVIIPKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYPDDLPNTSIVIVFHNEAWSTLLRTVHSVINRSPRHLLVEILLVDDASERDFLKKKLEDYVKTL--EVPVRILRMEQRSGLIRARLRGAAATRGQVITFLDAHCECTVGWLEPLLSRIKEDRKAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRSYFEEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVVRVDYGDVSARKALREALQCKPFSWYLENIYPDSQIP-RRYFSLGEIRNVETNQCVDNMGRKE----NEKVGFFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLNGPVVMLKC-HHMKGNQMFEYDAEKGTFMHIITQSCLTISRLEDGTYGPTVEYCDDS-PLQTW 548          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
             +GPGE G+ V +  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y + LP TS++I+FHNEAWS LLRT HSV+NRSP   L E++L DD+S +  L  +LE YVKT   +  VRI+R + R GLIRARL GA A  G+V+ FLD+HCE T GWLEP+L RI + R+ ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR +LQCK F W+++N+ P+  IP R     G ++N ++N C+D + + E    N   G ++C +G    Q+FS +  K               +IR +  CL  +  NG V  + C   +   Q++ Y+ E  +L+++   QCLD  + ++    T++ C  S   Q+W
Sbjct:   54 HEGPGEMGKAVIIPKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYPDDLPNTSIVIVFHNEAWSTLLRTVHSVINRSPRHLLVEILLVDDASERDFLKKKLEDYVKTL--EVPVRILRMEQRSGLIRARLRGAAATRGQVITFLDAHCECTVGWLEPLLSRIKEDRKAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRSYFEEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVVRVDYGDVSARKALREALQCKPFSWYLENIYPDSQIP-RRYFSLGEIRNVETNQCVDNMGRKE----NEKVGFFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLNGPVVMLKC-HHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRS-QQW 547          

Query:  334 GPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYV-KTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            GPGE G+ V +  E+++ + ++ K   FN   S+ I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAW+ LLRT HSV+NRSP   L+EV+L DD+S +  L  +LE YV K + P   VRIVR + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI Q ++T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+I+ R  LR  LQCK F W+++NV P+  IP                                                +SL  V +S + N +I+ ++         CL  ++ NG V  + C   L   QLW Y+    SL+++   QCLD ++  +    +++ C  S   Q+W
Sbjct:   55 GPGEMGKPVVIPKEQHEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKNKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLEEVVLVDDASERDFLKRKLEQYVRKLEVP---VRIVRMEQRSGLIRARLKGASLSTGQVITFLDAHCECTMGWLEPLLSRIKQDKKTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDIATRASLRQKLQCKPFSWYLENVYPDSQIP---------------------------------------------RHYYSLGEV-FSYTANKEIRTDD--------LCLDVSKLNGPVMMLKC-HHLKGNQLWDYDPLKLSLVHVNSNQCLDKASEDDSQVPSVRDCTGSRS-QQW 513          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
             +GPGE G+ V +  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y + LP TS++I+FHNEAWS LLRT HSV+NRSP   L E++L DD+S +  L  +LE YVKT   +  VRI+R + R GLIRARL GA A  G+V+ FLD+HCE T GWLEP+L RI + R+ ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR +LQCK F W+++N+ P+  IP R                                              FSL  V +S + + +I+ ++         CL  +  NG V  + C   +   Q++ Y+ E  +L+++   QCLD  + ++    T++ C  S   Q+W
Sbjct:   54 HEGPGEMGKAVIIPKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYPDDLPNTSIVIVFHNEAWSTLLRTVHSVINRSPRHLLVEILLVDDASERDFLKKKLEDYVKTL--EVPVRILRMEQRSGLIRARLRGAAATRGQVITFLDAHCECTVGWLEPLLSRIKEDRKAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRSYFEEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVVRVDYGDVSARKALREALQCKPFSWYLENIYPDSQIPRR---------------------------------------------YFSLGEV-FSYTADKEIRTDD--------LCLDVSRLNGPVVMLKC-HHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRS-QQW 514          

Query:  481 CKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYV-KTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLM--NLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            CK  +Y + LP TSV+I+FHNEAWS LLRT HS++ RSP   L+E+IL DD+S +  L + LE Y  K   P   V IVR + R GLIRARL GA  + G+V+ FLD+HCE TTGWLEP+L RI   R+ ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V+S TMAGGLFA DR YF EIG+YD GM+IWGGENLE+SFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + +   G++S R  LR+ L+CK F WF++NV P   IP R+    G V+N ++N CLD + + E    N   G+++C +   + Q+FS +  K               ++R +  CL  +  NG V  + C   +   QLW Y+++   L+  +    QCLD +  ++    T++ C+     Q+W
Sbjct:    1 CKTKVYPDGLPKTSVVIVFHNEAWSTLLRTVHSIIGRSPRHMLEEIILVDDASERDFLKSPLEEYASKLPVP---VHIVRMESRSGLIRARLRGAAVSRGQVITFLDAHCECTTGWLEPLLARIKADRKNVVCPIIDVISDETFEYLAGSDM-TYGGFNWKLNFRWYPVPQSEMDRRKGDRTIPVRSPTMAGGLFAIDRDYFQEIGTYDAGMDIWGGENLEMSFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQVINKNNRRLAEVWMDNFKDFFYIISPGVTKVEYGDVSQRKALRDRLKCKPFSWFLENVYPNSQIP-RHYYSLGEVRNVETNQCLDNMGRKE----NEKIGIFNCHSMGGN-QVFSYTADK---------------ELRTDDLCLDVSRMNGPVLMLKC-HHMKGNQLWDYDQQMQKLIMRHTNSNQCLDKATEQDRQVPTMRECDGGRS-QQW 445          

Query:  325 YQKGP------GENGELV--SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYS-ESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSK-SNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCV------TELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            Y+K P      GE G+ V  +L  EE +  ++ + K   N   SDRISL R LP+  N  C+   Y+   LPTTSV+I F+NEAWS LLRT HSV+  SP   L E+IL DD S +  L   LE Y+ T      VR+VR++ R GL+RARL GA  A G+VL FLD HCE   GWLEP+L RI ++   ++ P+I+ I+   F Y G+    Q+G F W + FTW  +P H +K  K   D ++S TMAGGLFA  ++YF  +G+YD GME+WGGENLE SFR W CGGTLE HPCSHVGH+F    PY+    +     NS R  +VW+D YK L+Y   P  R    G+++ R  LR  LQCK+F WF++NV P+  +P+     +G +KN   SN C D    +E         +Y C +G    Q F         +   +I+ N     R+   C  A  +NG +D++T        + + E Q + + +E+GS+ ++  ++CL+A    N   + +      N  Q+W
Sbjct:   17 YEKPPLDSNALGEMGKAVRLNLEGEEKRKEEESINKHQINIYVSDRISLHRQLPEKWNPLCREKKYNYRQLPTTSVVIAFYNEAWSTLLRTVHSVLETSPDALLNEIILVDDYSDREHLRDRLEQYIATL---RKVRLVRARKREGLVRARLLGAGVATGDVLTFLDCHCECHVGWLEPLLERIAEEESAVVCPVIDVIEWNTFEYMGNAGEPQIGGFDWRLVFTWHTVPGHEQKRRKSPIDVIRSPTMAGGLFAVSKKYFDYLGTYDTGMEVWGGENLEFSFRIWQCGGTLEVHPCSHVGHVFPKQAPYS----RSKALANSVRAAEVWMDGYKELYYHRNPHARMEPFGDVTERRNLRERLQCKTFKWFLENVYPDIHVPEDRPGKFGMLKNRGLSNYCFDYNPPDENQVTGQRIILYGC-HGMGQNQFFEY-------TSEQEIRYNT----RQPEAC--AAVDNG-MDYLTMYYCHSKNSPVTENQKFDF-REDGSIFHILTQKCLEAVEQPNSGPLPLLRTCDGNTRQRW 528          

Query:  376 ENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYS-ESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSK-SNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTEL---IETQLWIYNKENGSLMNLKFKQCLDA-SNLKNMDRVTIQPCESSNPYQKWESQ 1890
            E K  ++ +++ A N   SDRISL R +PD R  ECKA  +    LPTTSV+I F+NEAWS LLRT HSV+  SP   L+E+IL DD S +  L + LE Y+ T      VR+VR+  R GL+RARL GA  A G+VL FLD HCE   GW+EP+L RI +K   ++ P+I++ID   F +Y  T    +G F W + F W  +PEH +     + + ++S TMAGGLFA  ++YF  IG+YD+GME+WGGENLE+SFR W CGG+LE HPCSHVGH+F    PY  P        N+ R  +VW+D YK  FY   P  R+   G++S R  LR  L CKSF+W++KN+ P+  +P+     +G ++N    + C+D    +    G +   +Y C +G    Q F  +  K       D++ N+  ++     C    +   +V    C  +      + +W + +E+G++ N     CL A         + I+PC   +  Q W  Q
Sbjct:   94 ERKLEEESIERYALNIYLSDRISLHRHIPDGRMYECKAQKFDYRRLPTTSVVIAFYNEAWSTLLRTVHSVLESSPAVLLREIILVDDFSDRAYLKSPLEDYISTL---ERVRLVRTTQREGLVRARLLGATHATGQVLTFLDCHCECVPGWIEPLLQRIWEKETAVVCPVIDTIDWNTFEFYMQTSEPAIGGFDWRLTFQWHGVPEHERSRRASRIEPIQSPTMAGGLFAVSKKYFDHIGTYDQGMEVWGGENLELSFRVWQCGGSLEVHPCSHVGHVFPKKAPYPRPRFLQ----NTVRAAEVWMDSYKEHFYNRNPPGRKEKYGDLSERKTLREKLGCKSFEWYLKNIYPDLHVPEDRPGFHGAIQNKGIQSECIDYNAPDNNPTGAM-LSLYPC-HGQGGNQFFEYTTRK-------DLRFNSATEL-----CAEVRDGKPQVAMRHCPPDSQSNPPSVMWDF-REDGTVYNAHRNACLTAFRKPDGRADIEIRPCMPDDKNQMWTFQ 582          

Query:  349 GELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            G + S  D+E ++L    +K AFN   S+R+   R++PD R+  C    Y   LPT SV+I F+NEA SALLRT HSV  R+PP  L EV+L DD S  V L   LE  +K ++P  V ++VR++ R GLIR R+ GA  A G+VLVFLDSHCEV   WLEP+L R+ +   T++ PII+ ++   F Y  S  V   G F W +HF W  +P         +   +KS TMAGGLFA DR+YF ++G YD GM+IWGGENLEISFR WMCGG+LE  PCS +GHIFR   PY  P   D    NS R+  VWLD+YK  +   RPELRE   G++S R  LR  L C+ F W+++NV PE             ++  +  L   +L         +H      Q G    ++  L   K  ++ N+                   +E  G V    C +  IE Q+W+YN+  G  + L    CLD   ++      +  C  S   Q+W
Sbjct:    1 GMIYSREDQETRDLG--YQKHAFNLLISNRLDPHRTIPDTRHPRCATKSYPAQLPTASVVICFYNEAVSALLRTVHSVTERTPPALLHEVLLVDDFSDLVDLREGLEKELKEKFPKKV-KLVRNEKREGLIRGRMVGANHATGDVLVFLDSHCEVNVAWLEPLLARVAENPSTVVCPIIDIVNPDTFLYSASPLV--RGGFNWGLHFRWDPVPSSLLSGPDGEMAPIKSPTMAGGLFAMDRKYFNKLGQYDGGMDIWGGENLEISFRIWMCGGSLEIIPCSRIGHIFRKRRPYGSPAGADTMSRNSLRLAHVWLDEYKEQYLALRPELREREYGDVSERKALRERLGCRPFRWYLQNVYPE-------------IEVGRPQLPQAVL-------SKMHKRPKPVQRG----RLRHLQTGKCLVAHND------------------PSEKGGLVVVRPCDSGDIE-QVWVYNE--GQELQLANLLCLDMPEMEPRASPRLMKCHGSGGSQQW 461          

Query:  334 GPGENGELVS---LTDEENKNLDDVMKKEAFNRPTSDRISLQRSL-PDFRNSEC--KAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQV---GTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELRE----ANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDL-LVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCV----TELIET-QLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWE 1884
             PG +G       L+ EE    +  M+K  FN   SD++SL R L PD R  EC  + F    S+P+TSVII+FHNEAWS LLRT HSV+  SP   LKE+IL DD+S    L   L+ YVK      +V++VR + R GLI ARL GA  A GEVL FLD+HCE   GWLEP+L RI Q   +++ P I +ID   F     +        G F W + F W+ IP   +   K +T  ++S T AGGLF+  ++YF  +G+YD+ MEIWGGEN+E+SFR W CGG LE  PCS VGH+FR   P+TFP        N  R+ +VW+DDYK +FY    +  E       G+++ R +LR+ LQCK+F W++ NV PE F+PD +   +G +KN     CLD    QNE  +  +   +Y C +G    Q F  S  K       +++ N    + +E  CL A    G +    C     + L  T +LW    E     N+  +QCL +      +  T+ PC+  + +Q+WE
Sbjct:  120 APGASGRAYKTDDLSPEEKAIKEKGMEKHCFNVYASDKVSLHRDLGPDTRPPECIEQKFKRCPSMPSTSVIIVFHNEAWSTLLRTVHSVMYTSPSVLLKEIILVDDASVDDYLKGPLDEYVKQF---GIVKVVRQQERKGLITARLLGASVAQGEVLTFLDAHCECFNGWLEPLLARIRQNETSVVSPDISTIDMNTFEVNKPSAYSPAHNRGNFDWGLTFGWEPIPSRERTLRKDQTYPIRSPTFAGGLFSISKKYFEYLGTYDDQMEIWGGENIEMSFRVWQCGGQLEIIPCSIVGHVFRTKSPHTFPQGVSVITRNLVRLAEVWMDDYKDIFYRRNSQAAEIVKNKAYGDVTWRKRLRDKLQCKNFTWYLTNVYPEMFVPDLHPNIFGAIKNKAKGNCLDTGSFQNEVGKPLI---LYPC-HGMGGNQYFEYSSQK-------ELRHN----VAKEM-CLHAA--MGAMHLEDCKYKGGSSLPPTYELWELRPEK-LFFNMGTQQCLTSKG----ENPTMAPCDHMDEHQQWE 629          

Query:  340 GENGELVSLTDEENKNL-DDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAF--IYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRA-THPYTFP-GNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNN--DIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            G  G+   L  EENK L +      +FN   SD+ISL R+L D R+  CKA    Y   LPTTSVII FH E  S LLRT HSV+NR+PP  L EVI+ DD S    LG  L+ +V  Q+    V+++R K R GL+RARL+GA  A G+VL FLDSHCE T GW EP+L RI   R  ++ P IE I+A  F+Y GST+  Q G F W + F W+ IP   +K     +D +++ TMAGGLF+  RQYFF+IGSYDE M+IWGGENLE+SFR WMCGG LE   CS VGH+FR  T PY FP G +     N  R+ +VW+D+YK L+Y  +P+ + ++ G+IS R++LR  L+CKSF W++ N+ P+  +P+ +    G V+N  SN CLD L        N   G+Y+C +G    Q+    P +    + N  D+   +P                  V+ + C   +   Q W +++E G+LM+   +QCLD  +  +   V + PC+     Q+W
Sbjct:    8 GGGGKPAFLESEENKKLAEKYFANHSFNWLLSDKISLDRTLDDVRSERCKAKHNTYPAKLPTTSVIICFHKERLSVLLRTVHSVINRTPPELLAEVIVVDDFSQDAKLGKPLDDHV-AQF--TKVKVLRMKKREGLVRARLQGANTAKGDVLTFLDSHCEATPGWAEPLLARIAADRRNVVCPAIEVINADTFAYQGSTNADQRGGFSWDLFFKWKGIPPEEQKLRNDDSDPIRTPTMAGGLFSIHRQYFFDIGSYDEEMDIWGGENLELSFRVWMCGGRLEIVTCSRVGHVFRKYTSPYKFPDGVERTLTKNFNRLAEVWMDEYKDLYYNKKPQAKNSDYGDISKRLELRKRLKCKSFKWYINNIYPDVQMPELDPPARGEVRNPSSNQCLDSLGAKP--EHNARVGIYTC-HGQGGNQVSKYMPRELIFEEENCFDVSKTHP---------------GAPVELMKC-HGMRGNQEWKHDREKGTLMHFTTQQCLDRGSPSDQYAV-MNPCDGRE-SQRW 504          

Query:  415 FNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSY--KVG-LGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTF-PGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQN 1566
            FN   S +++L RS+PD R   C +  Y   LPT SVIIIFHNEAWS LLRT HSV+ RSPP  L+E++L DD S     G LG++LE+Y+ +Q+    V+++R+  R GLIRARL GAK A GEVLVFLDSHCE   GWLEP+L RI + R  ++ P IE ID + F Y         G F W + F W+ IPE+ ++  K  +D ++S TMAGGLFA D+ YF+EIGSYD  M  WGGEN+EISFR WMCGG+LE  PCS VGH+FR + PY    G  D    N+ R+ +VW+DDYK++FY  RP+L+  + G++SGR  LR  L CKSF W++ NV+ E  IPD   +G G ++N  +N CLD L +NE        G+Y C  
Sbjct:   15 FNELASSKVALDRSIPDNRPQSCLSLSYPTKLPTASVIIIFHNEAWSTLLRTVHSVLARSPPYLLREIVLVDDHSRLDTYGHLGSKLESYI-SQF--TKVQLIRAPKREGLIRARLIGAKQAKGEVLVFLDSHCEANLGWLEPLLARIGENRSIVVTPDIEVIDLRTFGYTHEHGANNRGIFNWELTFKWRGIPEYERRRRKSDSDPIRSPTMAGGLFAIDKSYFYEIGSYDTEMSFWGGENVEISFRIWMCGGSLEIIPCSKVGHVFRESQPYKIGEGAIDR---NNMRLAEVWMDDYKKIFYAMRPQLKGKDYGDVSGRKALRERLMCKSFKWYLDNVISELAIPDLYPIGRGEIRNLGTNTCLDTLAKNE---AGGEPGMYMCHG 393          

Query:  334 GPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAF--IYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRA-THPYTFP-GNKDYHGLNSKRMVDVWLDDYKRLFYLYR-PELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKF--IPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENN--GKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            G G+ GE  +L     ++        +FN   SDRISL R L D R  +CK    +Y  +LPTTSVII FHNEA S LLRT HSV+N SPPR + ++IL DD S    L   L  ++      N V+++R   R GL+ ARL GA+ A GEVL FLDSHCE T GWLEP+L RI + R  ++ P+IE I+A  F Y  S  + + G F W + FTW+ IPE  KK  K +TD ++S TMAGGLFA  ++YF+++GSYD  MEIWGGENLE+SFR WMCGG LE  PCS VGH+FR  T PY FP G       N  R+ +VW+D+YK  +Y  +  E R  + G+IS R+ LR  L CKSF W++ N+ P+    +P ++ L    ++N +S+LCLD L +    R     G+Y+C +G    Q F+L       + +N+I  N+         CL +   +    V+ ITC   L   Q W +NK  G+++++  + CLD S  ++   + + PC+ S+  Q+W
Sbjct:    1 GLGDLGEAATLPTRFKEHAAHAFDNHSFNVMLSDRISLDRRLKDVRGPKCKRKHKLYPRALPTTSVIICFHNEALSVLLRTVHSVLNESPPRLIADIILVDDYSEYDDLKQPLIDHISML---NKVKLIRMPSRQGLVPARLRGAEEARGEVLTFLDSHCEATPGWLEPLLVRIAEDRRNVVCPVIEVINADDFRYQASDVIHERGGFTWDLFFTWKAIPEAEKKRRKDETDYIRSPTMAGGLFAIHKKYFYDLGSYDSKMEIWGGENLEMSFRIWMCGGQLEIVPCSRVGHVFRKYTSPYKFPKGTTTTLARNFNRLAEVWMDEYKDHYYRKKTEEERNVDIGDISDRVALRKRLGCKSFKWYLDNIYPDMTNKLPPKSYLYSHQIRNKESSLCLDTLGEKNIKR----VGLYTC-HGMGGNQFFTL-------TKSNEILFNDD-------KCLDSPNGDPGSYVEMITC-HGLKGNQEWKHNKRMGTIVHVWTENCLDIS--QDGQFIIVNPCDGSST-QRW 499          

Query:  349 GELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPG----NKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQI 1587
            GE VS+     +  ++  +  +FN   SD +SL R LPD+RN  CKA  Y   LP +S+II FHNEAWS LLRT HSV+NR+PPR L+E++L DD+S +  L  +LE YV       VVRI+R   R GLIRARL+GA AA G +L FLD+HCE + GWLEP+  +I +    +++P+I+ I    F Y+   +    G F W + F W+ +P++  +  K + D +++  MAGGLF+ D+ YF +IG+YD GM+IWGGENLEISFR WMCGG +E  PCS VGH+FR   PY+FP     N D    N  R+ DVW+D+YK+ FY  R +L+     ++S R+ LR  L+CK+F W++ NV PE  +PD N    G V+N  S++CLD L + +    +   G+Y C +G    Q+
Sbjct:    4 GEAVSVPKRLKEKEEEGYELHSFNLVASDMMSLYRRLPDYRNDACKAKKYPLHLPKSSIIICFHNEAWSTLLRTVHSVINRTPPRLLEEILLIDDASNRDELKEKLEEYVAKL---KVVRIIRLSKRQGLIRARLKGAAAAKGSILTFLDAHCECSKGWLEPLAAKIAENSSNVVMPVIDEISDTTFYYHAVPEPFHRGVFRWRLEFGWKPVPQYEMERRKDEADGIRTPVMAGGLFSIDKNYFEKIGTYDTGMDIWGGENLEISFRIWMCGGAIEMLPCSRVGHVFRPRFPYSFPARPGHNTDVVSNNLMRVADVWMDEYKKHFYNIRFDLKRKQHDDVSQRLALREKLKCKNFKWYLDNVYPELEVPDTNFAASGQVRNPSSDMCLDTLGKKD----DTPLGLYQC-HGQGGNQV 412          

Query:  472 NSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIP 1443
              +C +  Y   LP+T+V+I FHNEAWS LLRT HSV++RSP   L+E++L DD S    L ++L AYV        VR++R+  R GLIRARL GA+AA G+V+ FLD+HCE    WL+P+L RIH  R  + VP+I+ I + +F Y G T    +G F W M FTW  +P + + E K +T  +++ TMAGGLF+ DR+YFFE GSYDEGM++WGGENLE+SFR W CGG LE  PCS VGH+FR   PY+FPG      +N  R+V VW+D+Y +  Y+ RP+L+    G+I+ R+ LRN L+CKSF W+++NV PE+  P
Sbjct:   23 QGKCSSKSYPSYLPSTTVVICFHNEAWSTLLRTVHSVIDRSPAHLLREILLIDDFSTHDYLKSKLTAYVAKL---RNVRVLRTSKREGLIRARLIGARAAKGDVITFLDAHCEANVDWLQPLLSRIHSDRTIVAVPVIDIISSTNFMYSG-TPSAVIGGFSWDMQFTWHSLPNNRQSERKDRTAPIRTPTMAGGLFSIDRKYFFESGSYDEGMDVWGGENLEMSFRIWQCGGKLEILPCSRVGHVFRTRFPYSFPGGYSEVSVNLARVVHVWMDEYNQYVYMKRPDLQSLKYGDITSRVALRNKLKCKSFKWYLENVYPEQTFP 342          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPC 1854
            + GPGE G+ V +  E  + + ++ K   FN   S+ I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAWS LLRT HSV++RSP   L+E++L DD+S +  L  +LE YV+    +  VR+VR + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI Q + T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R  LR  LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L+++   QCLD ++ ++    +++ C
Sbjct:   53 RDGPGEGGKPVVIPKENQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKNKLYPDDLPRTSVVIVFHNEAWSTLLRTVHSVIDRSPRSLLEEIVLVDDASERDFLKRQLEQYVRRL--EVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTLGWLEPLLTRIKQDKRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTIPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRTSLRQKLQCKPFSWYLENIYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVMMLKC-HHLKGNQLWEYDPVKLTLVHVNSNQCLDKASEEDSQVPSVRDC 538          

Query:  328 QKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPC 1854
            + GPGE G+ V +  E  + + ++ K   FN   S+ I+L RSLPD R   CK  +Y + LP TSV+I+FHNEAWS LLRT HSV++RSP   L+E++L DD+S +  L  +LE YV+    +  VR+VR + R GLIRARL+GA  + G+V+ FLD+HCE T GWLEP+L RI Q + T++ PII+ I    F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ DR YF EIG+YD GM+IWGGENLEISFR W CGGTLE   CSHVGH+FR   PYTFPG        N++R+ +VW+D++K  FY+  P + + + G+IS R  LR  LQCK F W+++N+ P+  IP R+    G ++N ++N CLD + + E    N   G+++C +G    Q+FS +  K               +IR +  CL  ++ NG V  + C   L   QLW Y+    +L+++   QCLD ++ ++    +++ C
Sbjct:   53 RDGPGEGGKPVVIPKENQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKNKLYPDDLPRTSVVIVFHNEAWSTLLRTVHSVIDRSPRSLLEEIVLVDDASERDFLKRQLEQYVRRL--EVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTLGWLEPLLTRIKQDKRTVVCPIIDVISDDTFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTIPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRTSLRQKLQCKPFSWYLENIYPDSQIP-RHYYSLGEIRNVETNQCLDNMARKE----NEKVGIFNC-HGMGGNQVFSYTANK---------------EIRTDDLCLDVSKLNGPVMMLKC-HHLKGNQLWEYDPVKLTLVHVNSNQCLDKASEEDSQVPSVRDC 538          

Query:  205 SKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            S+ N   + KD S L AL   IS       R H         +GPGE G+ V++  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y++ LPTTS++I+FHNEAWS LLRT HSV++RSP   L E++L DD+S +  L  +LE YV+T   +  V+I+R + R GLIRARL GA A  G+V+ FLD+HCE T GWLEP+L RI + R  ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ D+ YF EIGSYD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR +L+CK F W+++N+ P+  IP R     G ++N ++N C+D + + E    N   G ++C +G    Q+FS +  K               +IR +  CL  +  NG V  + C   +   Q++ Y+ E  +L+++   QCLD  + ++    T++ C  S   Q+W
Sbjct:   29 SECNKCDDRKDRSLLPALRAVIS-------RSH---------EGPGEMGKAVNIAKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYADDLPTTSIVIVFHNEAWSTLLRTVHSVISRSPRHLLVEIVLVDDASERDFLKKKLEGYVRTL--EVPVKILRMEQRSGLIRARLRGAAATTGQVITFLDAHCECTEGWLEPLLARIKEDRTAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKMYFEEIGSYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVMRVDYGDVSSRKALREALKCKPFAWYLENIYPDSQIP-RRYYSLGEIRNVETNQCVDNMGRKE----NEKVGFFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLNGPVVMLKC-HHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRS-QQW 547          

Query:  205 SKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            S+ N   + KD S L AL   IS       R H         +GPGE G+ V++  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y++ LPTTS++I+FHNEAWS LLRT HSV++RSP   L E++L DD+S +  L  +LE YV+T   +  V+I+R + R GLIRARL GA A  G+V+ FLD+HCE T GWLEP+L RI + R  ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ D+ YF EIGSYD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR +L+CK F W+++N+ P+  IP R     G ++N ++N C+D + + E    N   G ++C +G    Q+FS +  K               +IR +  CL  +  NG V  + C   +   Q++ Y+ E  +L+++   QCLD  + ++    T++ C  S   Q+W
Sbjct:   29 SECNKCDDRKDRSLLPALRAVIS-------RSH---------EGPGEMGKAVNIAKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYADDLPTTSIVIVFHNEAWSTLLRTVHSVISRSPRHLLVEIVLVDDASERDFLKKKLEGYVRTL--EVPVKILRMEQRSGLIRARLRGAAATTGQVITFLDAHCECTEGWLEPLLARIKEDRTAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKMYFEEIGSYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVMRVDYGDVSSRKALREALKCKPFAWYLENIYPDSQIP-RRYYSLGEIRNVETNQCVDNMGRKE----NEKVGFFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLNGPVVMLKC-HHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRS-QQW 547          

Query:  205 SKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPE-HFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNK-DYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            S+ N   + KD S L AL   IS       R H         +GPGE G+ V++  ++ + + ++ K   FN   SD I+L RSLPD R   CK  +Y++ LPTTS++I+FHNEAWS LLRT HSV++RSP   L E++L DD+S +  L  +LE YV+T   +  V+I+R + R GLIRARL GA A  G+V+ FLD+HCE T GWLEP+L RI + R  ++ PII+ I  + F Y   +D+   G F W ++F W  +P+    +    +T  V++ TMAGGLF+ D+ YF EIGSYD GM+IWGGENLE+SFR W CGG+LE   CSHVGH+FR   PY+FPG        N++R+ +VW+D++K  FY+  P +   + G++S R  LR +L+CK F W+++N+ P+  IP R     G ++N ++N C+D + + E    N   G ++C +G    Q+FS +  K               +IR +  CL  +  NG V  + C   +   Q++ Y+ E  +L+++   QCLD  + ++    T++ C  S   Q+W
Sbjct:   29 SECNKCDDRKDRSLLPALRAVIS-------RSH---------EGPGEMGKAVNIAKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYADDLPTTSIVIVFHNEAWSTLLRTVHSVISRSPRHLLVEIVLVDDASERDFLKKKLEGYVRTL--EVPVKILRMEQRSGLIRARLRGAAATTGQVITFLDAHCECTEGWLEPLLARIKEDRTAVVCPIIDVISDETFEYMAGSDM-TYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKMYFEEIGSYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVMRVDYGDVSSRKALREALKCKPFAWYLENIYPDSQIP-RRYYSLGEIRNVETNQCVDNMGRKE----NEKVGFFNC-HGMGGNQVFSYTADK---------------EIRTDDLCLDVSRLNGPVVMLKC-HHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRS-QQW 547          

Query:  109 MRIHFKNKKILICITILFGIFLITHNKFKISDSKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKWESQFGPQ 1902
            MRIHFKNKKILICITILFGIFLITHNKFKISDSKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNIS RIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTAT+NNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQ+WESQFGPQ
Sbjct:    1 MRIHFKNKKILICITILFGIFLITHNKFKISDSKLNNDLNVKDTSFLLALGINISTYNYRANRYHIYNTNQYYQKGPGENGELVSLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISSRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATKNNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQEWESQFGPQ 598          

Query:  109 MRIHFKNKKILICITILFGIFLITHNKFKISDSKLNNDLNVKDTSFLLALGINISTYN-------------YRANRYHIYNTNQYYQKGPGENGELV-----SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSY-YGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPYQKW 1881
            M+I +K  KI IC  ILF I L    K K  +    +  N+ + + +  L ++    N               A   H  +  +     PGE+G+ V     +LT EE +  D   K  AFN   S+ IS+ R LPD R+ ECK + Y+  LP TSVI+ FHNEAWS LLR+ HS++NRSP   LKEVIL DD S    L + LE Y+       +V+IVR+  R GLIRARL GA AA GEVL FLDSH E T GWLEP+L  I Q  + + VP+I+ I      Y + S    QVG F W++ F W  IP+  K   K  TD V + TMAGGLF+  ++YF  +G YD G +IWGGENLE+SF+ WMCGG +   PCS VGHIFR   PY++    +   +N  R+ +VWLD+YK  +Y+ R      + GNIS R+ LR +LQCK F W++ N+ P+ F+P  + L  G ++N    +C+D  +        + +  Y C N   + Q + LS                  +IRR+  CL   + +GK          +  Q W Y  E+  +  +    C++ +  +  D++ + PC S++  QKW
Sbjct:    1 MKILYKKNKIYICTGILFIIVLYVIFKSKTPEINSEDHKNLPNNNVVAKLSMSDKDKNPVPKLNENNEKNINIAAPKHNGDLKRIL---PGEDGKPVVIDVKNLTKEEKEKFDLGWKNNAFNEYASNLISIHRHLPDMRDEECKNYKYATKLPETSVILCFHNEAWSVLLRSVHSIINRSPKHLLKEVILVDDFSSMEHLKSPLEEYISQL---KIVKIVRATKREGLIRARLLGASAASGEVLTFLDSHIECTEGWLEPLLDPIAQSWKNVTVPVIDVISDDTLQYMHSSAKQVQVGGFSWNLIFNWHVIPDRDKIGRK-PTDPVNTPTMAGGLFSISKKYFDHLGGYDPGFDIWGGENLELSFKIWMCGGIMRIIPCSSVGHIFRKRSPYSWKPKVNVLKVNLVRLAEVWLDEYKEFYYM-RINHDLGDYGNISERVALRKNLQCKPFKWYLDNIYPDLFVPS-DALNSGEIRNMVKPMCVDGNIDGHDQTVPIIS--YPCHNQGGN-QFWMLSKTG---------------EIRRDLSCL---DFDGKQLTGYPCHGALGNQFWKY-MESKQIRQMNHNLCIELA--EKDDKLIMAPC-SNSLRQKW 576          

Query:  334 GPGENGELVS-----LTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYY-GSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCL 1680
            GPGE G  V      L+ +E +  D   K  A+N   S+ IS++R LPD+R+  C  + Y + LP TSVI+ FHNEAWSALLR+ HS+++RSPP  ++E+IL DD S    L   LE YV        V+I+R+K R GLIRARL G   A GEVL FLDSH E T GWLEP+L RI +    + VP+I+ ID    + +    D  QVG F W++ F W  IPE      + KTD V S TMAGGLF+  ++YF  +G+YD G +IWGGENLEISF+ WMCGG LE  PCSHVGHIFR   PY++ G+ +    NS R+ +VWLDDYK+ +Y  R      N G++S R KLR  L C +F W++ NV PE F+P  + L  G V+N  + +CLD  + ++ + G     +Y C     + Q + LS                  +IRR+ GC+
Sbjct:  116 GPGEMGRDVKIDEKLLSSQEKEKYDKGWKDHAYNEYASNMISVRRKLPDYRHKLCLTYKYLKPLPRTSVILCFHNEAWSALLRSVHSILDRSPPELIEEIILVDDKSTMKHLFEPLENYVSQL---KKVKIIRTKKREGLIRARLIGGSIAKGEVLTFLDSHIECTQGWLEPLLDRIARNWSNVPVPVIDIIDDTTLALHVAEADDVQVGGFDWNLQFNWHVIPERENARREKKTDPVSSPTMAGGLFSISKKYFEYLGTYDSGFDIWGGENLEISFKIWMCGGKLEIIPCSHVGHIFRKRSPYSW-GSGNVLRKNSIRLAEVWLDDYKKYYYT-RFNFDLGNFGDVSERKKLRQKLNCTTFKWYLDNVYPELFVPSES-LRSGEVRNPVTGMCLDASIDSK-ESGPNKVIMYPCHKQGGN-QYWMLS---------------KGGEIRRDEGCM 547          

Query:  340 GENGELVSLTDEENKNLDDVM------KKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSY-YGSTDVGQVGTFWWSMHFTWQDIPEHFKKEIKLKTDTVKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKDYHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIPDRNILGYGYVKNSKSNLCLD 1503
            GENG +    +E N +  D+       K   FN   S++IS+ R+LPDFR  +C ++ YS++LP TSVII FHNEAWS LLR+ HS+++RSP   LKE+IL DD S+   L ++LE Y+       +V+IVR+  R GLIRAR+ G++ A GE+L FLDSH E T GWLEP+L  I Q    + +P+I++ID   F + + S++  QVG F W + FTW  IP    K  +L TD V S TMAGGLF+  ++YF  +G YD G +IWGGENLEISF+ WMCGGTL   PCS VGHIFR   PY+    KD+   N  R+ +VWLDDYK+ FY  R +   +  G++S RI LR +L C +F W++ N+ P+ FIP  + +  G +KN  +N+C++
Sbjct:  101 GENG-IAEYVNETNISPSDLSRYNEGWKNYCFNEFLSNKISITRNLPDFREKQCFSYKYSDNLPQTSVIICFHNEAWSVLLRSVHSIISRSPKNLLKEIILVDDFSHLDHLKSQLEEYMAQL---KIVKIVRTTQREGLIRARMIGSRTATGEILTFLDSHIECTPGWLEPLLDPIAQNWSNVTIPVIDNIDKSTFEFAHQSSEYIQVGGFTWDLVFTWHYIPTR-DKVGRLPTDPVNSPTMAGGLFSISKKYFEYLGEYDPGFDIWGGENLEISFKIWMCGGTLRIVPCSVVGHIFRMKSPYSSTSKKDFLKNNLVRLAEVWLDDYKQ-FYYSRIKFNRSEIGDLSDRINLRKNLNCHNFKWYIDNIYPDMFIPS-DAVNKGEIKNLATNICIE 488          

Query:  256 LGINISTYNYRANRYHIYNTNQYYQKGPGENGELV-----SLTDEENKNLDDVMKKEAFNRPTSDRISLQRSLPDFRNSECKAFIYSESLPTTSVIIIFHNEAWSALLRTAHSVVNRSPPRFLKEVILFDDSSYKVGLGTELEAYVKTQWPDNVVRIVRSKIRLGLIRARLEGAKAAFGEVLVFLDSHCEVTTGWLEPILFRIHQKRETMIVPIIESIDAKHFSYYGSTDVGQ----VGTFWWSMHFTWQDIPEHFKKEIKLKTDT----VKSATMAGGLFASDRQYFFEIGSYDEGMEIWGGENLEISFRTWMCGGTLETHPCSHVGHIFRATHPYTFPGNKD-YHGLNSKRMVDVWLDDYKRLFYLYRPELREANAGNISGRIKLRNSLQCKSFDWFVKNVVPEKFIP-DRNILGYGYVKNSKSNLCLDLLVQNEFDRGNLHTGVYSCQNGASSAQIFSLSPVKYSISDNNDIKANNPCQIRREWGCLTATENNGKVDFITCVTELIETQLWIYNKENGSLMNLKFKQCLDASNLKNMDRVTIQPCESSNPY--QKW 1881
            + I  S++    N + IY         PGE G         LT+ E        +K  FN   SDRIS++RS+PD R+ ECK   + E+LPTTS++I+FHNEAWS LLRT HS+++RSP   LKE++L DD+S    L + L  YVK   P  +V+IVRS+ R+GL++AR+ GA+   GEVL FLD+H E   GWLEP+L RI +   T++ PIIESI+   F    ++++GQ    VG F W M F WQ     F   I ++  T    VKS  MAGGLF+  R YF+E+G+YD GM+IWG EN+E+S R WMCGG LE  PCSHVGH+FR+  PY++  + D    +N +R+V+VWLD+YK ++Y         + GNI GR+KLR  L+C SF W++KNV P  + P     +G      SK N CLD    NE  R      ++ C N   + Q+F +S   +       ++  N C             +  K+   TC  + +E++ W Y+ E     NL + +  +   +   + V +Q C    P   QKW
Sbjct:  154 VKIKNSSFKIEENEFTIY-PRLNDPNAPGEGGRPFRINKDELTESEKAEYKSGWEKHQFNLYASDRISVRRSIPDQRSKECKEMKFLENLPTTSIVIVFHNEAWSTLLRTIHSIIDRSPGHLLKEIVLVDDASTFEHLKSRLNDYVK---PLKIVKIVRSETRVGLMKARIIGAEETSGEVLTFLDAHIECYPGWLEPMLERIAENNRTVVCPIIESINDNTFE---ASNLGQNTISVGVFDWKMQFNWQ-----FADTINIQRLTRESPVKSPAMAGGLFSIMRTYFYELGTYDPGMKIWGSENVEMSLRIWMCGGILEIIPCSHVGHVFRSRSPYSWGESIDKILTINQRRLVEVWLDEYKEVYYSLTGNRDRYDIGNIQGRMKLRRKLKCHSFQWYLKNVFPSLYDPLSSKFMGSIESFASKGN-CLD--SGNENSRT---VKLFPCHNLGGN-QLFLISQTGF-------LRTINKCF------------SQNKLLLNTCDKDPVESR-WKYDDE----TNLIYDKQNNCVAINTNENVEVQTCSFEVPSIEQKW 669