Caspase-7

Overview
NameCaspase-7
Smed IDSMED30029698
Length (bp)952
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Caspase-7 (SMED30029698) t-SNE clustered cells

Violin plots show distribution of expression levels for Caspase-7 (SMED30029698) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Caspase-7 (SMED30029698) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Caspase-7 (SMED30029698) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029698

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30029698h1SMcG0005072 PL05007A1A02smed_ncbi_20240424PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pharynxSMED30029698h1SMcG0005072 Contig2992GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30029698h1SMcG0005072 Contig2992GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30029698h1SMcG0005072 Contig2992GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pharynxSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30029698h1SMcG0005072 dd_Smed_v4_1167_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Caspase-7 vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 214.157 bits (544), Expect = 1.400e-67
Identity = 111/261 (42.53%), Postives = 156/261 (59.77%), Query Frame = 2 
Query:   77 NLEINKLMDSVDSKENNDYFTNENKL--CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG-----DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            N+ +  +  + D      Y  N  KL  C IINN+ FD    + VR+GT +D E L   FR LGF V  + +C+   M   L++ S+  +  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G     D+N   KIP+EAD L  YSTVPGY+SWR+   GSW+VQALC+  E++ K  +++ +L RVN  VA +F+S + +   H K QIP    ML K ++ 
Sbjct:   17 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT-NAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 276
[Close]
BLAST of Caspase-7 vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 214.157 bits (544), Expect = 2.851e-67
Identity = 111/261 (42.53%), Postives = 156/261 (59.77%), Query Frame = 2 
Query:   77 NLEINKLMDSVDSKENNDYFTNENKL--CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG-----DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            N+ +  +  + D      Y  N  KL  C IINN+ FD    + VR+GT +D E L   FR LGF V  + +C+   M   L++ S+  +  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G     D+N   KIP+EAD L  YSTVPGY+SWR+   GSW+VQALC+  E++ K  +++ +L RVN  VA +F+S + +   H K QIP    ML K ++ 
Sbjct:   41 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDH-TNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 300
[Close]
BLAST of Caspase-7 vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 214.157 bits (544), Expect = 3.237e-67
Identity = 111/261 (42.53%), Postives = 156/261 (59.77%), Query Frame = 2 
Query:   77 NLEINKLMDSVDSKENNDYFTNENKL--CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG-----DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            N+ +  +  + D      Y  N  KL  C IINN+ FD    + VR+GT +D E L   FR LGF V  + +C+   M   L++ S+  +  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G     D+N   KIP+EAD L  YSTVPGY+SWR+   GSW+VQALC+  E++ K  +++ +L RVN  VA +F+S + +   H K QIP    ML K ++ 
Sbjct:   42 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT-NAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 301
[Close]
BLAST of Caspase-7 vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 214.157 bits (544), Expect = 3.237e-67
Identity = 111/261 (42.53%), Postives = 156/261 (59.77%), Query Frame = 2 
Query:   77 NLEINKLMDSVDSKENNDYFTNENKL--CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG-----DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            N+ +  +  + D      Y  N  KL  C IINN+ FD    + VR+GT +D E L   FR LGF V  + +C+   M   L++ S+  +  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G     D+N   KIP+EAD L  YSTVPGY+SWR+   GSW+VQALC+  E++ K  +++ +L RVN  VA +F+S + +   H K QIP    ML K ++ 
Sbjct:   42 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT-NAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 301
[Close]
BLAST of Caspase-7 vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 214.157 bits (544), Expect = 3.237e-67
Identity = 111/261 (42.53%), Postives = 156/261 (59.77%), Query Frame = 2 
Query:   77 NLEINKLMDSVDSKENNDYFTNENKL--CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG-----DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            N+ +  +  + D      Y  N  KL  C IINN+ FD    + VR+GT +D E L   FR LGF V  + +C+   M   L++ S+  +  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G     D+N   KIP+EAD L  YSTVPGY+SWR+   GSW+VQALC+  E++ K  +++ +L RVN  VA +F+S + +   H K QIP    ML K ++ 
Sbjct:   42 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT-NAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 301
[Close]
BLAST of Caspase-7 vs. Ensembl Celegans
Match: ced-3 (Cell death protein 3 Cell death protein 3 subunit p17 Cell death protein 3 subunit p15 Cell death protein 3 subunit p13 [Source:UniProtKB/Swiss-Prot;Acc:P42573])

HSP 1 Score: 144.436 bits (363), Expect = 7.267e-41
Identity = 93/278 (33.45%), Postives = 135/278 (48.56%), Query Frame = 2 
Query:  110 DSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNF-IQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGI-----------FADAGDSNN------------------IEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIEDHK 853
            D K     F++   +C IINNE F+    +  R+GT+ D + L  LFR +G+TV    N T   ML  + + ++ ++  D ++ V  ILSHG+E +I G D+  I    +           L  KPK+ F+QACRG+R D G            F   G  N                     K P +ADIL+ Y+T   Y SWRNS+ GSW++QA+C  F  +AK  DVV LL  VN  VA  F+++ G   S+   Q+P  T  L K+ +   + +
Sbjct:   14 DEKTMYRNFSSPRGMCLIINNEHFE---QMPTRNGTKADKDNLTNLFRCMGYTVICKDNLTGRGMLLTIRDFAKHESHGDSAILV--ILSHGEENVIIGVDDIPISTHEIYDLLNAANAPRLANKPKIVFVQACRGERRDNGFPVLDSVDGVPAFLRRGWDNRDGPLFNFLGCVRPQVQQVWRKKPSQADILIAYATTAQYVSWRNSARGSWFIQAVCEVFSTHAKDMDVVELLTEVNKKVACGFQTSQG---SNILKQMPEMTSRLLKKFYFWPEAR 283
[Close]
BLAST of Caspase-7 vs. Ensembl Celegans
Match: ced-3 (Cell death protein 3 Cell death protein 3 subunit p17 Cell death protein 3 subunit p15 Cell death protein 3 subunit p13 [Source:UniProtKB/Swiss-Prot;Acc:P42573])

HSP 1 Score: 144.821 bits (364), Expect = 2.791e-39
Identity = 90/265 (33.96%), Postives = 134/265 (50.57%), Query Frame = 2 
Query:  134 FTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNF-IQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGI-----------FADAGDSN--------------NIEKI----PIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            F++   +C IINNE F+    +  R+GT+ D + L  LFR +G+TV    N T   ML  + + ++ ++  D ++ V  ILSHG+E +I G D+  I    +           L  KPK+ F+QACRG+R D G            F   G  N               ++++    P +ADIL+ Y+T   Y SWRNS+ GSW++QA+C  F  +AK  DVV LL  VN  VA  F+++ G   S+   Q+P  T  L K+ + 
Sbjct:  238 FSSPRGMCLIINNEHFE---QMPTRNGTKADKDNLTNLFRCMGYTVICKDNLTGRGMLLTIRDFAKHESHGDSAILV--ILSHGEENVIIGVDDIPISTHEIYDLLNAANAPRLANKPKIVFVQACRGERRDNGFPVLDSVDGVPAFLRRGWDNRDGPLFNFLGCVRPQVQQVWRKKPSQADILIAYATTAQYVSWRNSARGSWFIQAVCEVFSTHAKDMDVVELLTEVNKKVACGFQTSQG---SNILKQMPEMTSRLLKKFYF 494
[Close]
BLAST of Caspase-7 vs. Ensembl Celegans
Match: csp-1 (Caspase A Caspase A subunit p16 Caspase A subunit p14 [Source:UniProtKB/Swiss-Prot;Acc:G5EBM1])

HSP 1 Score: 103.99 bits (258), Expect = 6.886e-26
Identity = 70/259 (27.03%), Postives = 128/259 (49.42%), Query Frame = 2 
Query:   98 MDSVDSKENNDYFTNENKLCY-----------IINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGD-EGIIYGRD----NFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIE-------------------ADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTG 769
            M   D+K++N    +++K CY           I++NE F    N+  R GT++D   L  LF+KL +TV   +N  A+ ML+ ++E ++  +       + F+LSHGD  G ++G D    N +++   L Y +      L+ KPK   + ACRG + + G+  D   +   +  PI                    AD+++ +ST  G+ S+R+   G+WY++++C  F K++K+  ++ +L     NV + +++  G
Sbjct:    1 MPRTDAKKSN----HKHKYCYEMNSNPRGTVLILSNENFK---NMERRVGTKQDEVNLTKLFQKLQYTVICKRNLEAESMLEAIKEFAEMAHTDS---IILFLLSHGDGAGSVFGIDDMPVNVMEVSTYLAYHQN-----LLLKPKWVAVSACRGGKLNMGVPVDGLPALEDKCAPISKFWNLMMSRIMPGTFTSLNADVIISFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHSKTMHLLDILTETGRNVVTKYENVQG 244
[Close]
BLAST of Caspase-7 vs. Ensembl Celegans
Match: csp-1 (Caspase A Caspase A subunit p16 Caspase A subunit p14 [Source:UniProtKB/Swiss-Prot;Acc:G5EBM1])

HSP 1 Score: 103.605 bits (257), Expect = 1.635e-24
Identity = 70/259 (27.03%), Postives = 128/259 (49.42%), Query Frame = 2 
Query:   98 MDSVDSKENNDYFTNENKLCY-----------IINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGD-EGIIYGRD----NFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIE-------------------ADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTG 769
            M   D+K++N    +++K CY           I++NE F    N+  R GT++D   L  LF+KL +TV   +N  A+ ML+ ++E ++   +      + F+LSHGD  G ++G D    N +++   L Y +      L+ KPK   + ACRG + + G+  D   +   +  PI                    AD+++ +ST  G+ S+R+   G+WY++++C  F K++K+  ++ +L     NV + +++  G
Sbjct:  269 MPRTDAKKSN----HKHKYCYEMNSNPRGTVLILSNENFK---NMERRVGTKQDEVNLTKLFQKLQYTVICKRNLEAESMLEAIKEFAE---MAHTDSIILFLLSHGDGAGSVFGIDDMPVNVMEVSTYLAYHQN-----LLLKPKWVAVSACRGGKLNMGVPVDGLPALEDKCAPISKFWNLMMSRIMPGTFTSLNADVIISFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHSKTMHLLDILTETGRNVVTKYENVQG 512
[Close]
BLAST of Caspase-7 vs. Ensembl Celegans
Match: csp-2 (Putative inactive caspase B Putative inactive caspase B subunit p31 Putative inactive caspase B subunit p17 Putative inactive caspase subunit p14 [Source:UniProtKB/Swiss-Prot;Acc:Q9TZP5])

HSP 1 Score: 92.4337 bits (228), Expect = 1.385e-21
Identity = 68/234 (29.06%), Postives = 110/234 (47.01%), Query Frame = 2 
Query:  119 ENNDYFTNENKLC--YIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIP-----------------IEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSN 763
            E   Y  N +  C   IINN  F     +  R G+ +D +KL  LF +LG+   ++ N  +  +L+ + + +Q  N  D    +  I+SHGD+G++YG D      ++L          L  KPK      CRGDR D+ +  D    N  ++ P                  +AD+LV +ST PG+ S+R+ + G+WY+Q L     +NAK   +  LL+  N  V   ++++
Sbjct:   14 ETRKYRNNRSSKCRAIIINNVVF---CGMEKRIGSDKDKKKLSKLFERLGYQSTSYDNLKSSEILETVRQFTQ-SNHGDS--LIITIMSHGDQGLLYGVDGVPV--QMLDIIDLMCTASLAKKPKWLMCVCCRGDRIDRAVRCDGFIDNFFDRFPKFFQFMKSKFPSHQTSSSQADLLVSFSTSPGFLSFRDETKGTWYIQELYRVIIENAKDTHLADLLMETNRRVVEKYEAD 239
[Close]
BLAST of Caspase-7 vs. Ensembl Fly
Match: Dcp-1 (gene:FBgn0010501 transcript:FBtr0072062)

HSP 1 Score: 181.03 bits (458), Expect = 1.602e-54
Identity = 98/238 (41.18%), Postives = 139/238 (58.40%), Query Frame = 2 
Query:  134 FTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFD------KGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKL-QIPSFTCMLRK 826
             +++++   +I N EF    +L  R+GT  D ++LK  F  LGF V  HK+C    +LK++ + ++  +  +  + V  ILSHG+ G +Y +D   ++D +  YF    C  L GKPKLFFIQAC+GDR D      KG+    G+S+   KIPI AD L  YST+PGYFSWRN +NGSWY+Q+L  E   N K  D+++LL  VN  VA +F+SN        +  QIP  T ML +
Sbjct:   73 MSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHVGKAAELDHTDNDCLAVA-ILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQKQIPCLTSMLTR 309
[Close]
BLAST of Caspase-7 vs. Ensembl Fly
Match: Drice (gene:FBgn0019972 transcript:FBtr0085482)

HSP 1 Score: 180.644 bits (457), Expect = 3.513e-54
Identity = 98/258 (37.98%), Postives = 144/258 (55.81%), Query Frame = 2 
Query:   74 YNLEINKLMDSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADA------GDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGE-KQSHGKLQIPSFTCMLRK 826
            Y   + K++    + E N    N   +  I N+E F+    L  R+GT  D E L  + ++L F V  +K+C    +L+ +E  +  +N  D    +  ILSHG+ G IY +D   ++D +  +F    C  L GKPKLFFIQAC+GDR D G+          GDS+   KIP+ AD L+ YSTVPG++SWRN++ GSW++Q+LC E   N K  D+++LL  V   VA +F+S T +  + H + QIP  T ML +
Sbjct:   70 YRKNVAKMVTDRHAAEYNMRHKNRG-MALIFNHEHFEVP-TLKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRTIE-YAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDGDSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTR 324
[Close]
BLAST of Caspase-7 vs. Ensembl Fly
Match: Decay (gene:FBgn0028381 transcript:FBtr0083304)

HSP 1 Score: 131.339 bits (329), Expect = 1.184e-35
Identity = 80/232 (34.48%), Postives = 121/232 (52.16%), Query Frame = 2 
Query:  206 RSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGI----FA----------DAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSD-------DVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            R GT+RD + ++A  +  GF V    + T   +   L+E++ R++      FV  ++SHG EG +Y +D    ++RL   F G+ CK L  KPKLFFIQACRG   +K +    FA           A        IP  ADILV YST   +FS+RN  +GSW++Q+LC   ++ A ++       +++ LL  VN  VA  ++SNT  +  +   ++P+F   L K   L
Sbjct:   72 RVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVA-REDHSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTKTFQL 302
[Close]
BLAST of Caspase-7 vs. Ensembl Fly
Match: Dronc (gene:FBgn0026404 transcript:FBtr0076347)

HSP 1 Score: 93.5893 bits (231), Expect = 5.109e-21
Identity = 58/218 (26.61%), Postives = 99/218 (45.41%), Query Frame = 2 
Query:  206 RSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGD-----EGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGD--------------SNNIEKIPIE-------ADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQS 781
            R G ++D + L  LF++L FT+  + N   D   K L  ++    +++   FV  +++HG+     E + +   + + + ++  +F+  KC  LV KPK+     CRGD +D G   + G+                  E IP         AD LV Y+  PGY + R+   GSWY+Q  C     +A   D+  +L + +  V  N ++  G  Q+
Sbjct:  213 RIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVG-NKRTKKGSMQT 429
[Close]
BLAST of Caspase-7 vs. Ensembl Fly
Match: Strica (gene:FBgn0033051 transcript:FBtr0335289)

HSP 1 Score: 86.6557 bits (213), Expect = 1.388e-18
Identity = 70/231 (30.30%), Postives = 104/231 (45.02%), Query Frame = 2 
Query:  140 NENKL----CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCML 820
             +NKL     YI N+E FD K     R G+ +D + L+A F +L   VE   + T  + +K    + Q K+ +D S  V  ILSHG         +          F   + + L  KPKL F+QAC+GD    G   DA   N         +IL  YST  G+ S+R + +G+ ++Q LC    ++ K+ D+ ++++ V   V    K            QIPS T  L
Sbjct:  306 TKNKLKPARVYIFNHERFDNKNEF--RKGSAQDVKVLRATFEQLKCKVEVITDATL-VTIKKTVRMLQTKDFEDKSALVLVILSHGTRHDQIAAKDDDYSLDDDVVFPILRNRTLKDKPKLIFVQACKGDCQLGGFMTDAAQPNGSPN-----EILKCYSTYEGFVSFR-TEDGTPFIQTLCEALNRSGKTSDIDTIMMNVRQVVKMQSKDR----------QIPSVTSTL 517
[Close]
BLAST of Caspase-7 vs. Ensembl Zebrafish
Match: casp3b (caspase 3, apoptosis-related cysteine peptidase b [Source:ZFIN;Acc:ZDB-GENE-070607-1])

HSP 1 Score: 215.312 bits (547), Expect = 3.246e-68
Identity = 107/252 (42.46%), Postives = 154/252 (61.11%), Query Frame = 2 
Query:  107 VDSKENND------YFTNENKL--CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +D+K ++D      Y TN   L  C IINN+ F  +  + VR+GT  D +K+   F +LGF V ++ + T   M+  L + SQ  + K  +MF C +LSHGD+G+IYG DN I++ RL  +F+G++C  LVGKPKLFFIQACRG   D GI  D       ++IP+EAD L  YST PGY++WRN +NGSW++ +LC+   K  K  +++ ++ RVN  VA  F+S++      GK QIP    ML K ++ 
Sbjct:   33 MDAKSHSDDNVDYQYKTNYPNLGQCLIINNKNFHKRTGMGVRNGTDEDAKKVFETFSQLGFKVGHYNDLTVSQMMALLNKASQEDHSKS-AMFACVLLSHGDDGLIYGTDNSIELKRLFAHFRGDRCTSLVGKPKLFFIQACRGTDLDSGIECDGVGDEETQRIPVEADFLYAYSTAPGYYAWRNVANGSWFISSLCDMLLKYGKQLEIMQVMTRVNHKVALEFESSSNLPGFDGKKQIPCIVSMLTKELYF 283
[Close]
BLAST of Caspase-7 vs. Ensembl Zebrafish
Match: casp7 (caspase 7, apoptosis-related cysteine peptidase [Source:ZFIN;Acc:ZDB-GENE-050522-506])

HSP 1 Score: 212.616 bits (540), Expect = 2.912e-66
Identity = 109/236 (46.19%), Postives = 147/236 (62.29%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG--------DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD K  ++VR+GT RD  +L   F+ LGF V  + + T   M + L+ +S+  +  D S F C +LSHG+EG+IYG D  + I  +   FKG+ CK LVGKPKLFFIQACRG  FD G+  D+G        D+N   KIP+EAD L  YSTVPGY+SWRN   GSW+VQALCN   +  K  +++ +L RVN  VA++F+S + + +   K QIP    ML K ++ 
Sbjct:  115 CIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKSLGFDVAVYNDQTCRNMERLLKAVSEEDH-SDSSCFACILLSHGEEGMIYGTDGAMPIKTMTSLFKGDVCKSLVGKPKLFFIQACRGSEFDDGVQTDSGPPNDTIETDANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLSEFGKQLEIMQILTRVNYMVATSFESWSEDPRFSEKKQIPCVVSMLTKELYF 349
[Close]
BLAST of Caspase-7 vs. Ensembl Zebrafish
Match: casp3a (caspase 3, apoptosis-related cysteine peptidase a [Source:ZFIN;Acc:ZDB-GENE-011210-1])

HSP 1 Score: 194.897 bits (494), Expect = 3.567e-60
Identity = 93/232 (40.09%), Postives = 139/232 (59.91%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIE----KIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD +  ++ R+GT  D   +  +FRKLG+ V+ + + T   +++ L  ++   + +  S+ VC +LSHGDEG+ +G D  + +  L   F+G++C  LVGKPKLFFIQACRG   D G+  D  D  +I     +IP+EAD L  YSTVPGY+SWRN+  GSW++Q+LC    K     +++ ++ RVN  VA +F+S +       K QIP    ML K ++ 
Sbjct:   50 CIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYIVKVYNDQTVAQIMQVLTTVAHDDHSRCASL-VCVLLSHGDEGVFFGTDTSVDLKSLTSLFRGDRCPSLVGKPKLFFIQACRGTELDPGVETDHPDHPDIPDGRVRIPVEADFLYAYSTVPGYYSWRNTMTGSWFIQSLCEMMTKYGSELELLQIMTRVNHKVALDFESTSNMPGFDAKKQIPCIVSMLTKEMYF 280
[Close]
BLAST of Caspase-7 vs. Ensembl Zebrafish
Match: casp3a (caspase 3, apoptosis-related cysteine peptidase a [Source:ZFIN;Acc:ZDB-GENE-011210-1])

HSP 1 Score: 194.897 bits (494), Expect = 3.567e-60
Identity = 93/232 (40.09%), Postives = 139/232 (59.91%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIE----KIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD +  ++ R+GT  D   +  +FRKLG+ V+ + + T   +++ L  ++   + +  S+ VC +LSHGDEG+ +G D  + +  L   F+G++C  LVGKPKLFFIQACRG   D G+  D  D  +I     +IP+EAD L  YSTVPGY+SWRN+  GSW++Q+LC    K     +++ ++ RVN  VA +F+S +       K QIP    ML K ++ 
Sbjct:   50 CIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYIVKVYNDQTVAQIMQVLTTVAHDDHSRCASL-VCVLLSHGDEGVFFGTDTSVDLKSLTSLFRGDRCPSLVGKPKLFFIQACRGTELDPGVETDHPDHPDIPDGRVRIPVEADFLYAYSTVPGYYSWRNTMTGSWFIQSLCEMMTKYGSELELLQIMTRVNHKVALDFESTSNMPGFDAKKQIPCIVSMLTKEMYF 280
[Close]
BLAST of Caspase-7 vs. Ensembl Zebrafish
Match: casp6b.1 (caspase 6b.1, apoptosis-related cysteine peptidase [Source:ZFIN;Acc:ZDB-GENE-041010-48])

HSP 1 Score: 157.147 bits (396), Expect = 5.902e-46
Identity = 85/236 (36.02%), Postives = 129/236 (54.66%), Query Frame = 2 
Query:  152 LCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGI-------FADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +  I N ++FD KL L  R+GT +D + L + F++L F V+ + + + D +L  ++E S   ++ D   FVC  LSHG++G +Y  D  I+I  +   FKG+KC+ LVGKPK+F  QACRGD+ D  +          A D+  +  +P  AD ++ YST  G+ S+R   NGSWY+Q LC    +         +L  VN  V+     N   + + GK Q+P F  ML KR++ 
Sbjct:    8 MALIFNQKQFDWKLGLKTRNGTDKDRDDLVSRFQELNFEVKAYNDYSRDDVLLKIQEASAADHV-DADCFVCIFLSHGEDGHVYANDKKIEIPEITDLFKGDKCRSLVGKPKIFIWQACRGDKLDDAVTEMSVEDVEMAVDAGVLYTLPAGADFIMCYSTAEGFCSFREPLNGSWYIQDLCEILGRYHSELQFTDILTLVNMKVSLRSVPNCRNRAAIGKKQMPCFASMLTKRLFF 242
[Close]
BLAST of Caspase-7 vs. Ensembl Xenopus
Match: casp3.2 (caspase 3, gene 2 [Source:NCBI gene;Acc:100151728])

HSP 1 Score: 202.986 bits (515), Expect = 3.633e-63
Identity = 103/236 (43.64%), Postives = 146/236 (61.86%), Query Frame = 2 
Query:  143 ENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGD--SNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIE 844
            E  +C IINN+ F    N+ VR+GT  D  KL   F  LG+ V+   +  ++ +   L+++S+  + K  S FVC ILSHG++G++YG D  IQI  L   F+G++CK LVGKPKLFFIQACRG   D GI  D+G      I++IP+EAD L  YSTVPGY+SWRN+ NGSW++Q+LC   +      +++ +L  VN  VA  F+S + ++  H K QIP    ML K  + ++
Sbjct:   54 EMGICLIINNKNFQSSTNMGVRNGTDVDARKLHETFTGLGYKVKVCNDQKSNDIFTLLKKMSEEDHSKR-SSFVCAILSHGEDGLVYGVDGPIQIKNLTDLFRGDRCKTLVGKPKLFFIQACRGTDLDSGIETDSGSEPGEEIQRIPVEADFLYAYSTVPGYYSWRNTMNGSWFIQSLCEMIKLYGPHLELIQILTCVNHMVALEFESCSTQQAFHAKKQIPCVVSMLTKAFYFLK 288
[Close]
BLAST of Caspase-7 vs. Ensembl Xenopus
Match: lrrc38 (leucine rich repeat containing 38 [Source:Xenbase;Acc:XB-GENE-955337])

HSP 1 Score: 186.422 bits (472), Expect = 1.094e-56
Identity = 106/239 (44.35%), Postives = 139/239 (58.16%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGF--TVENHKNCT-ADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG--------DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD    +S R+GT  D   L   F+ LGF  TV N+K+CT  + +L+++ E    ++ KD + F C  LSHG+EG+IYG D  + I                GKPKLFFIQACRG  FD G+  DAG        D+N   KIP+EAD L  YSTVPGY+SWRN   GSW+VQALCN   ++ K  +V+ +L RVN  VA+ F+S   + Q + K QIP    ML K ++ 
Sbjct:   72 CIIINNKNFDDITGMSPRNGTDIDARDLLRCFKGLGFDVTVFNNKSCTEMETLLRSVAE----QDHKDSACFACIFLSHGEEGLIYGTDGAMPIK---------------GKPKLFFIQACRGCEFDDGLETDAGPSNDSLETDANPRHKIPVEADFLYAYSTVPGYYSWRNPGRGSWFVQALCNVLNEHGKELEVMQILTRVNYLVATQFESYCDDPQFNKKKQIPCVVSMLTKELYF 291
[Close]
BLAST of Caspase-7 vs. Ensembl Xenopus
Match: ENSXETT00000003846.1 (caspase 3, gene 1 [Source:NCBI gene;Acc:100486222])

HSP 1 Score: 172.555 bits (436), Expect = 1.784e-51
Identity = 94/235 (40.00%), Postives = 137/235 (58.30%), Query Frame = 2 
Query:  143 ENKLCYIINNEEFD--PKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEK-IPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +  +C I+  E+FD  PK   S  S   + F  L  +F K+GF V   +N TAD +   L++I+ R++  +   FVC ++SHGD+   Y RD   +ID L   F+GE CK L+GKPKLFFIQACRGD+ D G+  DAG +      IP E D L  Y+T PGYF+WR  + GSW++Q+LC    +  +  D++ +L RVN  VA  + SN+ +   + K ++  F  ML K ++ 
Sbjct:   39 QKSICLILCMEKFDNDPKGKRSRNSNDDKIF--LNNIFVKMGFEVRLEENKTADEIESLLKDIA-RQDHSERGCFVCVVISHGDKDFFYARDQEFKIDALAEPFRGENCKSLIGKPKLFFIQACRGDKTDSGVVKDAGIATTTASVIPTECDFLFAYATPPGYFAWRRGA-GSWFIQSLCEMLGEYWQKRDLLQILTRVNHKVAYEYISNSTDTDKNEKKEMTCFLSMLTKELYF 269
[Close]
BLAST of Caspase-7 vs. Ensembl Xenopus
Match: calb2 (calbindin 2 [Source:Xenbase;Acc:XB-GENE-960001])

HSP 1 Score: 154.836 bits (390), Expect = 2.430e-44
Identity = 89/241 (36.93%), Postives = 131/241 (54.36%), Query Frame = 2 
Query:  152 LCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIF-ADAGDS---NNIEKI--------PIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            L  I N+E+F  +L L  R GT  D   L  +   LGF V+N+ N     +L+ ++E S   +  +   F+C  LSHG++  IY  D+ I I  L   FKG+KC+ LVGKPK+F  QACRG++ D  +   D  DS    NI ++        P  AD ++ YS   GY+S R + NGSWY+Q LC   + +A S +   +L  VN  V+    +   + ++ GK QIP F+ ML K+++L
Sbjct:   60 LALIFNHEDFYWQLRLGSRRGTNTDSMNLNRILTDLGFDVQNYYNLRTLDILEKIQEASTADH-SNADCFLCVFLSHGEDRHIYSYDSLIDIQELTNSFKGDKCESLVGKPKIFIFQACRGEKHDNPVLPTDETDSVTLTNITEVDAASLYTLPAGADFIMCYSVAEGYYSHRETVNGSWYIQDLCEVLKAHAASLEFTEILTLVNRKVSQRSVAFCNDPKAIGKKQIPCFSSMLTKKLFL 299
[Close]
BLAST of Caspase-7 vs. Ensembl Xenopus
Match: bmt2 (base methyltransferase of 25S rRNA 2 homolog [Source:Xenbase;Acc:XB-GENE-999766])

HSP 1 Score: 132.109 bits (331), Expect = 2.500e-34
Identity = 85/242 (35.12%), Postives = 125/242 (51.65%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLN----LSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRD-NFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIE---------KIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C +INN +F    +     S R GT +D E +  +F + G+  E HK+ TA+ + K LE  S++ + ++ S FVCFILSHG  G + G D   ++I RL  YF G+ C  L+ KPK+FFIQAC+G      +  +    ++            +P+EAD L  ++TV  Y S R+   GS Y+Q LC     +    D++ +L  VN  VA       G K      Q+PSF   LRK++ L
Sbjct:  260 CVVINNYDFREARSRDCKYSNREGTMKDAEDITKIFNERGYITEEHKDLTAENIRKTLEMYSKKDHAENDS-FVCFILSHGGIGTVCGCDGEEVEIKRLTKYFNGQHCPSLINKPKIFFIQACQGKESHPKVDINTDTESSFSFYEQDAMGTHLPLEADFLTAFATVEEYTSLRHIEKGSIYIQQLCKALTTHL-CQDLIDMLTFVNNEVAGMLFP-LGRKNV---TQMPSFKSELRKKLVL 495
[Close]
BLAST of Caspase-7 vs. Ensembl Mouse
Match: Casp7 (caspase 7 [Source:MGI Symbol;Acc:MGI:109383])

HSP 1 Score: 208.764 bits (530), Expect = 2.488e-65
Identity = 103/233 (44.21%), Postives = 146/233 (62.66%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIE-----KIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD    + VR+GT +D   L   F+ LGF V  H +C+   M   L + S+ ++  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G  N+I+     KIP+EAD L  YSTVPGY+SWRN   GSW+VQALC+   ++ K  +++ +L RVN  VA +F+S + + + + K QIP    ML K ++ 
Sbjct:   70 CIIINNKNFDKATGMDVRNGTDKDAGALFKCFQNLGFEVTVHNDCSCAKMQDLLRKASE-EDHSNSACFACVLLSHGEEDLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDIDANPRNKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFESQSDDPRFNEKKQIPCMVSMLTKELYF 301
[Close]
BLAST of Caspase-7 vs. Ensembl Mouse
Match: Casp3 (caspase 3 [Source:MGI Symbol;Acc:MGI:107739])

HSP 1 Score: 205.682 bits (522), Expect = 1.905e-64
Identity = 104/246 (42.28%), Postives = 149/246 (60.57%), Query Frame = 2 
Query:  107 VDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNI--EKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +DS    DY   E  +C IINN+ F     +S RSGT  D   L+  F  L + V N  + T + +L+ ++ +S+  + K  S FVC ILSHGDEG+IYG +  +++ +L  +F+G+ C+ L GKPKLF IQACRG   D GI  D+G    +  +KIP+EAD L  YST PGY+SWRNS +GSW++Q+LC+  +  A   + + +L RVN  VA+ F+S + +   H K QIP    ML K ++ 
Sbjct:   33 LDSSYKMDY--PEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVSKEDHSKR-SSFVCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKELYF 275
[Close]
BLAST of Caspase-7 vs. Ensembl Mouse
Match: Casp3 (caspase 3 [Source:MGI Symbol;Acc:MGI:107739])

HSP 1 Score: 205.682 bits (522), Expect = 1.905e-64
Identity = 104/246 (42.28%), Postives = 149/246 (60.57%), Query Frame = 2 
Query:  107 VDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNI--EKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +DS    DY   E  +C IINN+ F     +S RSGT  D   L+  F  L + V N  + T + +L+ ++ +S+  + K  S FVC ILSHGDEG+IYG +  +++ +L  +F+G+ C+ L GKPKLF IQACRG   D GI  D+G    +  +KIP+EAD L  YST PGY+SWRNS +GSW++Q+LC+  +  A   + + +L RVN  VA+ F+S + +   H K QIP    ML K ++ 
Sbjct:   33 LDSSYKMDY--PEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVSKEDHSKR-SSFVCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKELYF 275
[Close]
BLAST of Caspase-7 vs. Ensembl Mouse
Match: Casp7 (caspase 7 [Source:MGI Symbol;Acc:MGI:109383])

HSP 1 Score: 161.77 bits (408), Expect = 5.561e-48
Identity = 81/171 (47.37%), Postives = 108/171 (63.16%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIE-----KIPIEADILVGYSTVPGYFSWRNSSNGS 652
            C IINN+ FD    + VR+GT +D   L   F+ LGF V  H +C+   M   L + S+ ++  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G  N+I+     KIP+EAD L  YSTVPGY+SWRN   GS
Sbjct:   68 CIIINNKNFDKATGMDVRNGTDKDAGALFKCFQNLGFEVTVHNDCSCAKMQDLLRKASE-EDHSNSACFACVLLSHGEEDLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDIDANPRNKIPVEADFLFAYSTVPGYYSWRNPGKGS 237
[Close]
BLAST of Caspase-7 vs. Ensembl Mouse
Match: Casp8 (caspase 8 [Source:MGI Symbol;Acc:MGI:1261423])

HSP 1 Score: 156.377 bits (394), Expect = 1.587e-43
Identity = 102/281 (36.30%), Postives = 156/281 (55.52%), Query Frame = 2 
Query:   77 NLEINKLMDSV-----DSKENNDYFTNENK---LCYIINNEEFDPKLN-------LSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRD-NFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG-----------DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEF-EKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVW 835
            +L++ +L DS      +S+ ++  +  +NK    C IINN +F            +  R GT  D E L   F++L F + ++ +CTA+ + + LE   Q  + K+   F+C ILSHGD+G++YG D     I  L  YF G KC  L GKPK+FFIQAC+G  F KG+  +AG            S++   IP EAD L+G +TV    S+R+  NG+WY+Q+LC    E+  + DD++S+L  VN +V     SN  ++++ GK Q+P  T  LRK+++
Sbjct:  204 SLKMAELCDSPREQDSESRTSDKVYQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTANEIHEILEGY-QSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIFFIQACQGSNFQKGVPDEAGFEQQNHTLEVDSSSHKNYIPDEADFLLGMATVKNCVSYRDPVNGTWYIQSLCQSLRERCPQGDDILSILTGVNYDV-----SNKDDRRNKGK-QMPQPTFTLRKKLF 477
[Close]
BLAST of Caspase-7 vs. UniProt/SwissProt
Match: sp|P55210|CASP7_HUMAN (Caspase-7 OS=Homo sapiens OX=9606 GN=CASP7 PE=1 SV=1)

HSP 1 Score: 214.157 bits (544), Expect = 1.555e-66
Identity = 111/261 (42.53%), Postives = 156/261 (59.77%), Query Frame = 2 
Query:   77 NLEINKLMDSVDSKENNDYFTNENKL--CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG-----DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            N+ +  +  + D      Y  N  KL  C IINN+ FD    + VR+GT +D E L   FR LGF V  + +C+   M   L++ S+  +  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G     D+N   KIP+EAD L  YSTVPGY+SWR+   GSW+VQALC+  E++ K  +++ +L RVN  VA +F+S + +   H K QIP    ML K ++ 
Sbjct:   42 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT-NAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 301
[Close]
BLAST of Caspase-7 vs. UniProt/SwissProt
Match: sp|Q8MJU1|CASP3_FELCA (Caspase-3 OS=Felis catus OX=9685 GN=CASP3 PE=2 SV=1)

HSP 1 Score: 208.379 bits (529), Expect = 1.029e-64
Identity = 108/255 (42.35%), Postives = 154/255 (60.39%), Query Frame = 2 
Query:   89 NKLMDS---VDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNI--EKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +K MDS   +D+    DY   E  LC IINN+ F     +  RSGT  D   L+  F  L + V N  + T + ++  L+ +S R++    S F+C +LSHG+EGIIYG +  + + +L G+F+G+ C+ L GKPKLF IQACRG   D GI  D+G  ++I  +KIP+EAD L  YST PGY+SWRNS +GSW++Q+LC+     A   + + +L RVN  VA+ F+S + +   HGK QIP    ML K ++ 
Sbjct:   24 SKSMDSGIYMDNSYKMDY--PEMGLCIIINNKNFHESTGMPSRSGTDVDAANLRETFTNLKYEVRNKNDLTREQIVALLDSVS-REDHSKRSSFICVLLSHGEEGIIYGTNGPVDLKKLTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTEDDIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLRLYAHELEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYF 275
[Close]
BLAST of Caspase-7 vs. UniProt/SwissProt
Match: sp|Q60431|CASP3_MESAU (Caspase-3 OS=Mesocricetus auratus OX=10036 GN=CASP3 PE=2 SV=1)

HSP 1 Score: 208.379 bits (529), Expect = 1.223e-64
Identity = 108/255 (42.35%), Postives = 155/255 (60.78%), Query Frame = 2 
Query:   89 NKLMDS---VDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNI--EKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +K MDS   +DS    DY   E  +C IINN+ F     ++ RSGT  D  KL+  F  L + V N  + T + +++ ++  S+  + K  S FVC ILSHGDEG+I+G D  I + +L  YF+G+ C+ L+GKPKLF IQACRG   D GI  D+G  +++  +KIP+EAD L  YST PGY+SWRN  +GSW++Q+LC+  +  A   + + +L RVN  VA+ F+S + +   H K QIP    ML K ++ 
Sbjct:   24 SKSMDSGIYLDSSYKMDY--PEMGVCIIINNKNFHKSTGMTPRSGTDVDAAKLRETFMALKYEVRNKNDLTREEIVELMKNASKEDHSKR-SSFVCVILSHGDEGVIFGTDGPIDLKKLTSYFRGDYCRSLIGKPKLFIIQACRGTELDCGIETDSGTEDDMTCQKIPVEADFLYAYSTAPGYYSWRNPKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKELYF 275
[Close]
BLAST of Caspase-7 vs. UniProt/SwissProt
Match: sp|P97864|CASP7_MOUSE (Caspase-7 OS=Mus musculus OX=10090 GN=Casp7 PE=1 SV=2)

HSP 1 Score: 208.764 bits (530), Expect = 1.741e-64
Identity = 103/233 (44.21%), Postives = 146/233 (62.66%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIE-----KIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD    + VR+GT +D   L   F+ LGF V  H +C+   M   L + S+ ++  + + F C +LSHG+E +IYG+D    I  L  +F+G++CK L+ KPKLFFIQACRG   D GI AD+G  N+I+     KIP+EAD L  YSTVPGY+SWRN   GSW+VQALC+   ++ K  +++ +L RVN  VA +F+S + + + + K QIP    ML K ++ 
Sbjct:   70 CIIINNKNFDKATGMDVRNGTDKDAGALFKCFQNLGFEVTVHNDCSCAKMQDLLRKASE-EDHSNSACFACVLLSHGEEDLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDIDANPRNKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFESQSDDPRFNEKKQIPCMVSMLTKELYF 301
[Close]
BLAST of Caspase-7 vs. UniProt/SwissProt
Match: sp|Q8MKI5|CASP3_CANLF (Caspase-3 OS=Canis lupus familiaris OX=9615 GN=CASP3 PE=2 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 3.763e-64
Identity = 111/258 (43.02%), Postives = 156/258 (60.47%), Query Frame = 2 
Query:   80 LEINKLMDSVDSKENN---DYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG--DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            L  +K MDS  S +N+   DY   E  LC IINN+ F     ++ RSGT  D   L+  F  L + V N  + T + +L+ +  +S+  + K  S FVC +LSHGDEGII+G +  + + ++ G+F+G+ C+ L GKPKLF IQACRG   D GI  D+G  D    +KIP+EAD L  YST PGY+SWRNS +GSW++Q+LC   +  A   + + +L RVN  VA+ F+S + +   HGK QIP    ML K ++L
Sbjct:   21 LHGSKSMDSGMSFDNSYKMDY--PEMGLCIIINNKNFHKSTGMAPRSGTDVDAANLRETFTNLKYEVRNKNDLTCEEILELMNSVSKEDHSKR-SSFVCVLLSHGDEGIIFGTNGPVDLRKVTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGIEDDMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYL 275
[Close]
BLAST of Caspase-7 vs. TrEMBL
Match: A0A4Y6I1G1 (Caspase-7 OS=Dugesia japonica OX=6161 GN=cas-7 PE=2 SV=1)

HSP 1 Score: 409.453 bits (1051), Expect = 1.300e-141
Identity = 191/249 (76.71%), Postives = 223/249 (89.56%), Query Frame = 2 
Query:   98 MDSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIE 844
            MD+VD+KE++ Y T++ KLCYIINNEEFD  LNLS RSGTQRDFEKLK LF+KL F VENHKNCTA  M KNLEEIS+RK+LKDYSMFVCFILSHGDEGIIYGRD F+ ID +L  FKG+KCKGLVGKPKLFFIQACRGDRFDKG+ AD+  SNN++KIPIEAD+L+GYSTVPGYFSWRNSSNGSWY+QALC+E EKNA+++DVV +LVRVNA+VA+NF SNTG+ +SHG +QIPSFTCMLRK+V L++
Sbjct:    1 MDTVDAKESDFYSTDKKKLCYIINNEEFDRTLNLSSRSGTQRDFEKLKTLFKKLNFVVENHKNCTAGEMRKNLEEISKRKDLKDYSMFVCFILSHGDEGIIYGRDAFVPIDSMLNLFKGDKCKGLVGKPKLFFIQACRGDRFDKGVVADSVGSNNLDKIPIEADVLIGYSTVPGYFSWRNSSNGSWYIQALCSEIEKNAETEDVVHILVRVNASVAANFSSNTGDIKSHGMIQIPSFTCMLRKKVLLVD 249
[Close]
BLAST of Caspase-7 vs. TrEMBL
Match: A0A493QY72 (Caspase-7 OS=Dugesia japonica OX=6161 GN=CASP-7 PE=2 SV=1)

HSP 1 Score: 408.683 bits (1049), Expect = 2.059e-141
Identity = 191/249 (76.71%), Postives = 222/249 (89.16%), Query Frame = 2 
Query:   98 MDSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIE 844
            MD+VD+KE++ Y T++ KLCYIINNEEFD  LNLS RSGTQRDFEKLK LF+KL F VENHKNCTA  M KNLEEIS+RK+LKDYSMFVCFILSHGDEGIIYGRD  + ID +L YFKG+KCKGLVGKPKLFFIQACRGD+FDKG+ AD+  SNN++KIPIEAD+L+GYSTVPGYFSWRNSSNGSWY+QALC+E EKNAK++DVV +LVRVNA+VA NF SNTG+ +SHG +QIPSFTCMLRK+V L++
Sbjct:    1 MDTVDAKESDFYSTDKKKLCYIINNEEFDRGLNLSPRSGTQRDFEKLKTLFKKLNFVVENHKNCTAYEMRKNLEEISKRKDLKDYSMFVCFILSHGDEGIIYGRDAHVSIDTMLNYFKGDKCKGLVGKPKLFFIQACRGDKFDKGVLADSVGSNNLDKIPIEADVLIGYSTVPGYFSWRNSSNGSWYIQALCSEIEKNAKTEDVVHILVRVNASVAGNFSSNTGDTKSHGMIQIPSFTCMLRKKVLLLD 249
[Close]
BLAST of Caspase-7 vs. TrEMBL
Match: A0A4Y6I1H4 (Caspase-3B OS=Dugesia japonica OX=6161 GN=cas-3B PE=2 SV=1)

HSP 1 Score: 337.035 bits (863), Expect = 6.926e-113
Identity = 154/247 (62.35%), Postives = 197/247 (79.76%), Query Frame = 2 
Query:   98 MDSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +D+VD +ENN Y  ++ KLCYII+NEEF P LNLS RSGT +DF++L+ +F+ L F VE  KNCT   + +NL+++SQRK+L   SM VC ILSHGDEGIIYG D  +++DRL GYFKG+KCKGL+GKPK+FFIQACRG ++DKG+ AD+  SN IEKIPIEAD L+GYSTVPGYFSWRN ++GSWY+QALC E  K +K+ ++V LLV+VN NVA+NFKS T +K++ G +QI SF CMLRK +W 
Sbjct:   16 LDTVDGQENNAYDMSQKKLCYIISNEEFQPHLNLSTRSGTDKDFKQLRQVFKTLKFEVEPFKNCTCRQINENLKQLSQRKDLDGVSMMVCIILSHGDEGIIYGTDGIVELDRLFGYFKGDKCKGLIGKPKIFFIQACRGQKYDKGVSADSIISNYIEKIPIEADFLIGYSTVPGYFSWRNGASGSWYIQALCKELIKCSKTHELVQLLVKVNNNVATNFKSKTNQKETDGMVQISSFVCMLRKSLWF 262
[Close]
BLAST of Caspase-7 vs. TrEMBL
Match: A0A4Y6I1I1 (Caspase-3A OS=Dugesia japonica OX=6161 GN=cas-3A PE=2 SV=1)

HSP 1 Score: 304.679 bits (779), Expect = 3.061e-100
Identity = 143/248 (57.66%), Postives = 183/248 (73.79%), Query Frame = 2 
Query:  101 DSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIE 844
            D VD      Y  ++ KLCYIINNEEF PKLNL  RSGT  DF+ LK +F KLGF VEN+KN   D +  NL E+S+RK LKD S+ VC IL+HG +GIIYG D  I++DR+ GYFKG+KC+ L+GKPK+F  QACRG++FDKG+ AD     ++EKIP+EAD L+GYSTV GYFSWRN  NGSWY+QALC E E++A+S +++ LLV VN  VA+N+ S T   ++   +QIPSF CMLRK +WL++
Sbjct:   10 DDVDGTIRECYDVSKIKLCYIINNEEFYPKLNLPTRSGTDEDFKSLKQVFTKLGFKVENYKNFKKDEICSNLRELSERKELKDVSILVCIILTHGADGIIYGIDGPIELDRIFGYFKGDKCRKLIGKPKVFLFQACRGEKFDKGVVADGFFQTSLEKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQALCRELERSAQSMELIQLLVNVNNYVATNYFSMTKNDKTDAMVQIPSFVCMLRKPLWLVD 257
[Close]
BLAST of Caspase-7 vs. TrEMBL
Match: A0A4Y6I0S1 (Caspase-3C OS=Dugesia japonica OX=6161 GN=cas-3C PE=2 SV=1)

HSP 1 Score: 247.669 bits (631), Expect = 5.708e-78
Identity = 122/236 (51.69%), Postives = 162/236 (68.64%), Query Frame = 2 
Query:  131 YFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            Y  N  KLCYIINNE F  K  L+ R+GT  DF+ +K  F KL F ++ + NC +  M++NL++IS + +LKDYS+FVC ILSHGDEGIIYG ++ ++I++LL  F  E C+ L  KPK+F IQAC+GD+ D G +AD+  SNNI K+ IE +  +GYSTVPGYFSWRN   GSW++ +LC+    N   +D+V LLVRVN N  S ++SN      + KLQI SF CML K V+L
Sbjct:   12 YPMNGKKLCYIINNELFHKKSGLTRRNGTNIDFKNIKITFEKLNFEIQWNDNCRSLEMIQNLQKISLKSDLKDYSIFVCVILSHGDEGIIYGFEDSVEINKLLAIFTEENCEALRDKPKIFLIQACKGDKCDSGAYADSIQSNNINKMFIEPNFFIGYSTVPGYFSWRNQVVGSWFISSLCDVINSNENREDLVQLLVRVN-NRVSKYRSNVNRNDMNNKLQISSFVCMLLKDVYL 246
[Close]
BLAST of Caspase-7 vs. Ensembl Cavefish
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:103041716])

HSP 1 Score: 214.927 bits (546), Expect = 2.704e-67
Identity = 111/236 (47.03%), Postives = 149/236 (63.14%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG--------DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD K  ++VR+GT RD  +L   F+ LGF V  + + T   M + L+E+S+ ++  D S F C +LSHG+EG+IYG D  + I  +   F+G+ CK LVGKPKLFFIQACRG  FD GI  D+G        D+N   KIP+EAD L  YSTVPGY+SWRN   GSW+VQALCN   +  K  +++ +L RVN  VA+NF+S + + +   K QIP    ML K ++ 
Sbjct:  108 CIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKNLGFDVFVYNDQTCAKMERLLKEVSE-EDHSDSSCFACILLSHGEEGMIYGTDGAMPIKSMTSLFRGDMCKSLVGKPKLFFIQACRGSEFDDGIQTDSGPPNDTIETDANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVATNFESWSEDPRFSEKKQIPCVVSMLTKELYF 342
[Close]
BLAST of Caspase-7 vs. Ensembl Cavefish
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:103041716])

HSP 1 Score: 214.927 bits (546), Expect = 2.704e-67
Identity = 111/236 (47.03%), Postives = 149/236 (63.14%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG--------DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD K  ++VR+GT RD  +L   F+ LGF V  + + T   M + L+E+S+ ++  D S F C +LSHG+EG+IYG D  + I  +   F+G+ CK LVGKPKLFFIQACRG  FD GI  D+G        D+N   KIP+EAD L  YSTVPGY+SWRN   GSW+VQALCN   +  K  +++ +L RVN  VA+NF+S + + +   K QIP    ML K ++ 
Sbjct:  108 CIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKNLGFDVFVYNDQTCAKMERLLKEVSE-EDHSDSSCFACILLSHGEEGMIYGTDGAMPIKSMTSLFRGDMCKSLVGKPKLFFIQACRGSEFDDGIQTDSGPPNDTIETDANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVATNFESWSEDPRFSEKKQIPCVVSMLTKELYF 342
[Close]
BLAST of Caspase-7 vs. Ensembl Cavefish
Match: casp3b (caspase-3 [Source:NCBI gene;Acc:103025383])

HSP 1 Score: 198.364 bits (503), Expect = 1.519e-61
Identity = 98/229 (42.79%), Postives = 134/229 (58.52%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADA-GDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN  FD    +S R+GT  D  K+  +F +LGF      N T   M + L   S+  + K  +MFVC +LSHGDEG I+G D  +++  L   F+G +C  L GKPKLFFIQACRG   D GI  D+  DS    KIP+EAD L  YST PGY+SWRN++NGSW++ +LC    K  +  +++ ++ RVN  VA  F+S++     +   QIP    ML K ++ 
Sbjct:   58 CIIINNRNFDRSTGMSDRAGTDVDAGKMLKVFSELGFKASVQNNRTVSQMRQILTSASKEDHSKS-AMFVCVMLSHGDEGTIFGTDGCMELKELTRLFRGNQCPSLAGKPKLFFIQACRGSELDPGIETDSVDDSEGTHKIPVEADFLYVYSTAPGYYSWRNTANGSWFISSLCEMLAKYGRELEIMQIMTRVNHKVALEFESSSNTPGFNAMKQIPCIMSMLTKELYF 285
[Close]
BLAST of Caspase-7 vs. Ensembl Cavefish
Match: casp3b (caspase-3 [Source:NCBI gene;Acc:103025383])

HSP 1 Score: 198.364 bits (503), Expect = 8.342e-58
Identity = 98/228 (42.98%), Postives = 134/228 (58.77%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADA-GDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVW 835
            C IINN  FD    +S R+GT  D  K+  +F +LGF      N T   M + L   S+  + K  +MFVC +LSHGDEG I+G D  +++  L   F+G +C  L GKPKLFFIQACRG   D GI  D+  DS    KIP+EAD L  YST PGY+SWRN++NGSW++ +LC    K  +  +++ ++ RVN  VA  F+S++     +   QIP    ML K ++
Sbjct:  469 CIIINNRNFDRSTGMSDRAGTDVDAGKMLKVFSELGFKASVQNNRTVSQMRQILTSASKEDHSKS-AMFVCVMLSHGDEGTIFGTDGCMELKELTRLFRGNQCPSLAGKPKLFFIQACRGSELDPGIETDSVDDSEGTHKIPVEADFLYVYSTAPGYYSWRNTANGSWFISSLCEMLAKYGRELEIMQIMTRVNHKVALEFESSSNTPGFNAMKQIPCIMSMLTKELY 695
[Close]
BLAST of Caspase-7 vs. Ensembl Cavefish
Match: ENSAMXT00000034295.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001829.1:2219:15770:-1 gene:ENSAMXG00000030411.1 transcript:ENSAMXT00000034295.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 186.422 bits (472), Expect = 5.239e-57
Identity = 91/228 (39.91%), Postives = 134/228 (58.77%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ F     ++ R+GT  D       F KLG+ V+   + T D + + L  +++  + +  S+ VC +LSHGDEG+ +G D  +++  L   F+G++C  LVGKPKLFFIQACRG   D GI  D+    +  KIP+EAD L  YST PGY+SWRN+  GSW++Q+LC    K  +  +++ ++ RVN  VA +F+S +       K QIP    ML K ++ 
Sbjct:   61 CIIINNKNFHRSTGMNQRNGTDVDAGNAMKAFGKLGYKVKVFNDQTVDQIKQVLTAVAREDHSRCASL-VCVLLSHGDEGVFFGTDGALELKSLTSLFRGDRCTSLVGKPKLFFIQACRGTDLDAGIEMDSPPDGSPVKIPVEADFLYAYSTAPGYYSWRNTMTGSWFMQSLCEMVSKYGRELELMQIMTRVNYKVAMDFESASNAPGFDAKKQIPCIVSMLTKEMYF 287
[Close]
BLAST of Caspase-7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005841.1 (pep scaffold:Pmarinus_7.0:GL476535:290070:293064:-1 gene:ENSPMAG00000005266.1 transcript:ENSPMAT00000005841.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 201.06 bits (510), Expect = 9.054e-64
Identity = 103/249 (41.37%), Postives = 148/249 (59.44%), Query Frame = 2 
Query:  113 SKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGI-------FADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            S + N +F  ++K C IINNE F P+  ++ R GT RD  +L+  F  LGF VE++K+ T   M++NL++ S   +    + FVC ILSHG+EG++YG D  + +  L   F  + C  L GKPKLFFIQACRG  FD+G+        +D  DS    K P+E D L  +STVPGY+SWRN   GSW++Q+LC E  +N+   ++V +LV VN  VA+ + S + +   + K QIP    ML +  + 
Sbjct:    3 SAQYNMHFQAKSK-CIIINNENFSPQTGMNRRKGTDRDAMQLQVCFLSLGFQVESYKDLTCKQMVENLKKASSEDH-GTRACFVCAILSHGEEGVLYGTDGTLPVSILADIFSEKHCPSLAGKPKLFFIQACRGSMFDEGVDQVDGLRRSDDTDSRGYSKPPVEPDFLYAFSTVPGYYSWRNEEKGSWFIQSLCEELLRNSSQLELVKILVCVNRRVATQYVSCSRDITYNDKKQIPCIMSMLTREFYF 249
[Close]
BLAST of Caspase-7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005440.1 (pep scaffold:Pmarinus_7.0:GL480504:970:21443:-1 gene:ENSPMAG00000004940.1 transcript:ENSPMAT00000005440.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 187.193 bits (474), Expect = 2.268e-58
Identity = 96/238 (40.34%), Postives = 144/238 (60.50%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGI--FADAGDSNNIEK--IP----IEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIE 844
            C IINNE F P+  ++ R+GTQ D  +L   F  LGF V+  K+ T + M   L+E+SQ +NLK+ +  VC +LSHG++G++YG D  + +  ++  F    C  LVGKP+L FIQACRG   DKG+      GD +  E   +P    ++ D L  ++TV GYFSWRN +NGS ++Q LC+E +++ +  ++  +L RVN  VA+ F SNT +   +   QIP    ML K ++L++
Sbjct:   13 CIIINNENFFPRAGMAKRNGTQMDVSRLSECFDSLGFDVKYRKDLTCEEMRTFLKEVSQ-ENLKNCACLVCVVLSHGEDGVVYGTDGPLPLSDIVKPFADSSCPSLVGKPRLVFIQACRGTLLDKGVDKVECDGDPDVKEASLLPTVDLMQPDFLFAFATVSGYFSWRNPANGSCFIQLLCSELQEHGQRMELTKILTRVNRRVATEFTSNTTDADLNNSKQIPCTVSMLTKELYLLK 249
[Close]
BLAST of Caspase-7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005498.1 (pep scaffold:Pmarinus_7.0:GL481204:7525:20312:1 gene:ENSPMAG00000004980.1 transcript:ENSPMAT00000005498.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 153.295 bits (386), Expect = 9.228e-43
Identity = 97/253 (38.34%), Postives = 137/253 (54.15%), Query Frame = 2 
Query:  140 NENKLCYIINNEEFD------PKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRD-NFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDR-------FDKGIFADAGDSNNIE-KIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAK-SDDVVSLLVRVNANVASNFK----SNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            N   +C IINNEEF       PKL    R GT  D EKL+ +F+ LGF +  H N T   M++ L   S + N K++ +FVC IL+HG+   ++G D   + I  +  YF G  CK L+GKPKLFFIQAC+G                  G  + I   IP EADIL+G +TV GY S+R+   GSWY+Q LCN  E+     +D++++L  VN  VA          T +++S  ++  P F+  LR +++L
Sbjct:  273 NPRGICLIINNEEFSSDFKTSPKLK--KREGTHIDAEKLEKVFKYLGFKILLHNNLTVGQMIETLMSCS-KMNHKNHDVFVCCILTHGEINCVFGSDGKSLLITEVTSYFNGSACKSLLGKPKLFFIQACQGHEKQSECHLAADADIDADGPVSPISYSIPDEADILLGMATVSGYLSFRHRREGSWYIQTLCNLLEQKCNGQNDILAILTDVNRVVAEKTARMKNPYTHKRESTKQMPQPKFS--LRMKLFL 520
[Close]
BLAST of Caspase-7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008527.1 (pep scaffold:Pmarinus_7.0:GL477443:35181:37755:1 gene:ENSPMAG00000007721.1 transcript:ENSPMAT00000008527.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 111.694 bits (278), Expect = 1.276e-30
Identity = 54/118 (45.76%), Postives = 76/118 (64.41%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQAC 508
            C IINN+ FD    +  R+GT  D + L+ LF+ +GF VE   N     M+  + E+++ K+ +  + FVC +LSHGDEG+IYG DN++ I  L   F+G+ C+ LVGKPKLFFIQ C
Sbjct:   24 CVIINNKTFDQSTGMGERTGTDVDRDMLEKLFKDIGFKVEVKNNMKRKEMVSYITEVAE-KDHRQCACFVCILLSHGDEGVIYGTDNYLPIRDLTTPFRGDLCRSLVGKPKLFFIQVC 140
[Close]
BLAST of Caspase-7 vs. Ensembl Sea Lamprey
Match: casp3a (caspase 3, apoptosis-related cysteine peptidase a [Source:ZFIN;Acc:ZDB-GENE-011210-1])

HSP 1 Score: 102.064 bits (253), Expect = 4.087e-27
Identity = 55/118 (46.61%), Postives = 76/118 (64.41%), Query Frame = 2 
Query:  497 IQACRGDRFDKG--IFAD---AGDSNNIEK--IPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSD-DVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRK 826
            +QACRG  FD+G  + AD     DS +I +  IP+EAD L  YSTVPGY+SWRN + GSW+VQA C   +++A S+ +++ LL RVN  VA ++ S + + +  GK QIP    ML K
Sbjct:    1 LQACRGTEFDEGSTMCADNDVETDSESISRQTIPVEADFLYCYSTVPGYYSWRNVATGSWFVQAFCKVLKESANSNLELMQLLTRVNRKVAYDYVSFSSDTRFSGKKQIPCIVSMLTK 118
[Close]
BLAST of Caspase-7 vs. Ensembl Nematostella
Match: EDO41832 (Caspase [Source:UniProtKB/TrEMBL;Acc:A7S364])

HSP 1 Score: 178.718 bits (452), Expect = 2.917e-53
Identity = 98/237 (41.35%), Postives = 149/237 (62.87%), Query Frame = 2 
Query:  152 LCYIINNEEFDPK--LNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFA-DAG--DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIED 847
            +  IINN++F P   ++   R+GT  D + L+  F+ L F VE H N T     + ++E+ QR +  +Y+  +  IL+HG+EGI+Y  D  I+I  ++  FKG+    LVGKPK+F  QAC+G  +  G  A DAG  D+N ++ +P+EAD L  YSTVPGY+SWRNS NGSW++Q++C  F K+  + DV+ ++ RVN+ + S ++S TG+  S  K Q+PS   MLRK ++   +
Sbjct:  157 VAVIINNKDFLPASGMHRYPRNGTNVDRDSLEKTFKALQFDVEVHNNKTTYETNRIIKELGQR-SYSNYNAMIFAILTHGEEGILYTTDGTIEIRSMMKAFKGDN---LVGKPKIFIFQACQGHEYMDGKDATDAGPEDANRVQ-VPVEADFLYAYSTVPGYYSWRNSVNGSWFIQSICEVFNKHMHNMDVLRMMTRVNS-LVSTYQSRTGDYYSDRKKQVPSIVSMLRKDLFFFPE 387
[Close]
BLAST of Caspase-7 vs. Ensembl Nematostella
Match: EDO34460 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPA7])

HSP 1 Score: 170.629 bits (431), Expect = 6.673e-52
Identity = 100/239 (41.84%), Postives = 131/239 (54.81%), Query Frame = 2 
Query:  152 LCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRD-NFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADA------GDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIED 847
            +C II+N+ FD K  L  R G ++D E LK  F  L F VE  ++ TA  M     E S   +   Y +FVC ILSHG  G IYG D N I+I+ +   FKG  C  L  KPKLFFIQACRG  FD+GI ADA       D+      P E+  L+GY+T PGY SWR+  +GSWY+  LC       +  D+V+++V+VN  V+  F          G  Q P+    LRKR++L E+
Sbjct:   13 ICLIISNQHFD-KPELRKRDGNEQDVENLKRTFENLHFVVEIRQDKTASEMYTIAREFSSIDH-SAYDLFVCCILSHGMLGSIYGSDSNLIEINEISSQFKGNACPTLAHKPKLFFIQACRGQDFDRGIQADATRDMDASDAVRQNAEPNESHFLLGYATPPGYVSWRSQVHGSWYISFLCEVLSTYCERYDLVTMMVKVNDKVSEAFTRK-------GYKQCPAPVVTLRKRIYLNEN 242
[Close]
BLAST of Caspase-7 vs. Ensembl Nematostella
Match: EDO41263 (Caspase [Source:UniProtKB/TrEMBL;Acc:A7S4V9])

HSP 1 Score: 169.088 bits (427), Expect = 6.639e-50
Identity = 94/230 (40.87%), Postives = 134/230 (58.26%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDN-FIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDS-NNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN  FD    L  R+G+  D   L++LF  L + V+   + T   M   L + ++  +    S+ VC ILSHG EG IYG D   + I  ++  F G + K L+GKPKLFF+QACRG  FD G   +  DS  +   +P EAD L+ Y+TVPGY SWR+   GSW++QAL   F+ +A ++DV+S+L++VN  VA  F+S   +K      Q+PS   ML K+++ 
Sbjct:  129 CLIINNVRFDADSGLKSRAGSDIDASNLQSLFMSLRYRVKRLNDLTMRQMKNTLFDFAKNNHKNSDSVVVC-ILSHGLEGRIYGVDGGLLNISDVISMFNGYQAKDLIGKPKLFFLQACRGGDFDHGARMEQIDSPTDKSSLPSEADFLIAYATVPGYVSWRHQEKGSWFIQALVEVFKTDATTEDVLSMLIKVNRKVALEFESFNRKK------QMPSPVVMLTKKLFF 351
[Close]
BLAST of Caspase-7 vs. Ensembl Nematostella
Match: EDO31855 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S119])

HSP 1 Score: 145.206 bits (365), Expect = 3.349e-42
Identity = 88/231 (38.10%), Postives = 136/231 (58.87%), Query Frame = 2 
Query:  161 IINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDN-FIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNI----EKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            IINN+EF  + ++  R G+  D ++L  LF   G TV+  +N T+  ML+ LEE S+ K+   +  F+C ILSHG    IYG D   +Q++ L   F+G  C  L GKPK+FF+QACRG +  K + A   DS  +      +P ++D L+ Y++ PGY S+RN   GSW+++++ + F    +++ ++ L++RVN  VAS   SN G K      Q+PS  CML ++V+ 
Sbjct:    7 IINNQEFPSRSDVE-RKGSAEDVKQLYQLFDDFGMTVKTIQNKTSLEMLELLEETSE-KDFTKFDCFICIILSHGSHSGIYGVDEKAVQVESLTNKFRGSTCPSLQGKPKVFFLQACRGAK--KELVAVESDSEPVPIRHSGLPSDSDFLICYASSPGYESYRNPELGSWFIRSIVDVFRNFGETEHLMDLMLRVNHRVAS-LNSNLGHK------QMPSEVCMLTRKVYF 226
[Close]
BLAST of Caspase-7 vs. Ensembl Nematostella
Match: EDO42564 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S119])

HSP 1 Score: 145.206 bits (365), Expect = 3.349e-42
Identity = 88/231 (38.10%), Postives = 136/231 (58.87%), Query Frame = 2 
Query:  161 IINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDN-FIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNI----EKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            IINN+EF  + ++  R G+  D ++L  LF   G TV+  +N T+  ML+ LEE S+ K+   +  F+C ILSHG    IYG D   +Q++ L   F+G  C  L GKPK+FF+QACRG +  K + A   DS  +      +P ++D L+ Y++ PGY S+RN   GSW+++++ + F    +++ ++ L++RVN  VAS   SN G K      Q+PS  CML ++V+ 
Sbjct:    7 IINNQEFPSRSDVE-RKGSAEDVKQLYQLFDDFGMTVKTIQNKTSLEMLELLEETSE-KDFTKFDCFICIILSHGSHSGIYGVDEKAVQVESLTNKFRGSTCPSLQGKPKVFFLQACRGAK--KELVAVESDSEPVPIRHSGLPSDSDFLICYASSPGYESYRNPELGSWFIRSIVDVFRNFGETEHLMDLMLRVNHRVAS-LNSNLGHK------QMPSEVCMLTRKVYF 226
[Close]
BLAST of Caspase-7 vs. Ensembl Medaka
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:101161677])

HSP 1 Score: 220.705 bits (561), Expect = 2.146e-70
Identity = 113/236 (47.88%), Postives = 148/236 (62.71%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG--------DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD    ++VR+GT RD  +L   F+ LGF V  + + T D M   L+E SQ  +  D S F C +LSHG+EG+IYG D  I I  +   F+G+KCK LVGKPKLFFIQACRG  FD+G+  D+G        D+N   KIP+EAD L  YSTVPGY+SWRN   GSW+VQALCN   +  K  +++ +L RVN  VA+NF+S + + +   K QIP    ML K ++ 
Sbjct:   50 CIIINNKNFDDNTGMNVRNGTDRDAGELYKCFKSLGFDVSIYNDQTCDKMEHLLKEASQEDH-SDSSCFACILLSHGEEGMIYGTDGAIPIKTMTSLFRGDKCKSLVGKPKLFFIQACRGSEFDEGVQTDSGPPNDTIETDANPSHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVANNFESWSEDPRYSEKKQIPCVVSMLTKELYF 284
[Close]
BLAST of Caspase-7 vs. Ensembl Medaka
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:101161677])

HSP 1 Score: 221.09 bits (562), Expect = 4.053e-70
Identity = 113/236 (47.88%), Postives = 148/236 (62.71%), Query Frame = 2 
Query:  155 CYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAG--------DSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            C IINN+ FD    ++VR+GT RD  +L   F+ LGF V  + + T D M   L+E SQ  +  D S F C +LSHG+EG+IYG D  I I  +   F+G+KCK LVGKPKLFFIQACRG  FD+G+  D+G        D+N   KIP+EAD L  YSTVPGY+SWRN   GSW+VQALCN   +  K  +++ +L RVN  VA+NF+S + + +   K QIP    ML K ++ 
Sbjct:   79 CIIINNKNFDDNTGMNVRNGTDRDAGELYKCFKSLGFDVSIYNDQTCDKMEHLLKEASQEDH-SDSSCFACILLSHGEEGMIYGTDGAIPIKTMTSLFRGDKCKSLVGKPKLFFIQACRGSEFDEGVQTDSGPPNDTIETDANPSHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVANNFESWSEDPRYSEKKQIPCVVSMLTKELYF 313
[Close]
BLAST of Caspase-7 vs. Ensembl Medaka
Match: casp3 (caspase 3 [Source:NCBI gene;Acc:100049215])

HSP 1 Score: 206.068 bits (523), Expect = 1.542e-64
Identity = 102/229 (44.54%), Postives = 145/229 (63.32%), Query Frame = 2 
Query:  152 LCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +C IINN+ F     +  R+GT  D       F KLG+ ++ + + T D M K   ++S + + K ++ F C ILSHG+EG+IYG D  +  ++L+   KG  C  LVGKPKLFFIQACRG  FD+GI  DA D  + EKIP+EAD L  YSTV GY+SWR+++NGSW++Q+LC   EK +K+ D++ ++ RVN  VA++F+S++      GK QIP    ML K  + 
Sbjct:   57 ICLIINNKNFHKDSGMGPRNGTDNDAAAAWKSFMKLGYEIQMYNDQTVDQMKKLFRQMSNQDHSK-FASFACVILSHGEEGVIYGTDGPVSFNKLIECLKGRSCLSLVGKPKLFFIQACRGTLFDEGIEHDAKDDTS-EKIPLEADFLFAYSTVSGYYSWRSTANGSWFIQSLCEMLEKFSKTLDLMQIMTRVNHKVATHFESSSNAPGFSGKKQIPCIVSMLTKDFYF 283
[Close]
BLAST of Caspase-7 vs. Ensembl Medaka
Match: casp3 (caspase 3 [Source:NCBI gene;Acc:100049215])

HSP 1 Score: 206.068 bits (523), Expect = 1.567e-64
Identity = 102/229 (44.54%), Postives = 145/229 (63.32%), Query Frame = 2 
Query:  152 LCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            +C IINN+ F     +  R+GT  D       F KLG+ ++ + + T D M K   ++S + + K ++ F C ILSHG+EG+IYG D  +  ++L+   KG  C  LVGKPKLFFIQACRG  FD+GI  DA D  + EKIP+EAD L  YSTV GY+SWR+++NGSW++Q+LC   EK +K+ D++ ++ RVN  VA++F+S++      GK QIP    ML K  + 
Sbjct:   59 ICLIINNKNFHKDSGMGPRNGTDNDAAAAWKSFMKLGYEIQMYNDQTVDQMKKLFRQMSNQDHSK-FASFACVILSHGEEGVIYGTDGPVSFNKLIECLKGRSCLSLVGKPKLFFIQACRGTLFDEGIEHDAKDDTS-EKIPLEADFLFAYSTVSGYYSWRSTANGSWFIQSLCEMLEKFSKTLDLMQIMTRVNHKVATHFESSSNAPGFSGKKQIPCIVSMLTKDFYF 285
[Close]
BLAST of Caspase-7 vs. Ensembl Medaka
Match: casp3a (caspase 3B [Source:NCBI gene;Acc:100049265])

HSP 1 Score: 197.208 bits (500), Expect = 1.674e-61
Identity = 98/229 (42.79%), Postives = 139/229 (60.70%), Query Frame = 2 
Query:  152 LCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            LC IINN+ FD    ++ R+GT  D      +F KLG+ V+ + + T   + + L ++S R +  D + FVC +LSHGDEG+ +G D  I++  L   F+G+ CK LVGKPKLFFIQACRG   D GI AD+ +  +  KIP+EAD L  +ST PGY+SWRN+  GSW++ +LC    K  K  +++ ++ RVN  VA  F+S +     H K QIP    ML K ++ 
Sbjct:   38 LCIIINNKNFDRGTGMNQRNGTDIDAASAMKVFSKLGYRVKIYNDQTVKQIKQLLTDVS-RMDHSDSASFVCILLSHGDEGVFFGTDGSIELKTLTSLFRGDHCKSLVGKPKLFFIQACRGTELDDGIEADSKE--DTTKIPVEADFLYAFSTAPGYYSWRNTMTGSWFINSLCEMLSKYGKELELLHIMTRVNHMVAVEFESISTLPGFHAKKQIPCIVSMLTKEMYF 263
[Close]
BLAST of Caspase-7 vs. Planmine SMEST
Match: SMESG000053168.1 (SMESG000053168.1)

HSP 1 Score: 515.383 bits (1326), Expect = 0.000e+0
Identity = 248/252 (98.41%), Postives = 251/252 (99.60%), Query Frame = 2 
Query:   98 MDSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIEDHK 853
            MDSVDSKENNDYF NENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRD+FIQIDRLLGYFKG+KCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEAD+LVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIEDHK
Sbjct:    1 MDSVDSKENNDYFINENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDHFIQIDRLLGYFKGDKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADVLVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIEDHK 252
[Close]
BLAST of Caspase-7 vs. Planmine SMEST
Match: SMESG000053166.1 (SMESG000053166.1)

HSP 1 Score: 307.76 bits (787), Expect = 5.351e-105
Identity = 142/246 (57.72%), Postives = 189/246 (76.83%), Query Frame = 2 
Query:  101 DSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            D VD KE+  Y  ++ KLC+IINNEEF P LN++ R+GT  DF++LK +F KLGF VEN+KN  +  +  NL+++SQRK LKD S+ V  ILSHG EG IYG D  + +DR+ GYFKG+KC+GL+GKPK+F IQACRGD++D G+ AD   SN+IEKIPIEAD L+GYSTV GYFSWRN  NGSWY+Q+LC+E E  +KS +++ +L+ VN  VA  ++S++ +++S GK+QIPSF CMLRK +WL
Sbjct:   17 DMVDGKESEIYEISKIKLCFIINNEEFQPNLNMAARNGTGVDFKRLKQVFTKLGFKVENYKNFKSSEICSNLKQLSQRKELKDISLLVVIILSHGTEGTIYGTDGPVDLDRIFGYFKGDKCRGLLGKPKVFLIQACRGDKYDHGVIADDFLSNSIEKIPIEADFLIGYSTVAGYFSWRNGKNGSWYIQSLCDELENLSKSCELLQILINVNNTVAEKYQSHSKKEKSDGKVQIPSFVCMLRKSLWL 262
[Close]
BLAST of Caspase-7 vs. Planmine SMEST
Match: SMESG000016936.1 (SMESG000016936.1)

HSP 1 Score: 234.187 bits (596), Expect = 2.908e-76
Identity = 117/230 (50.87%), Postives = 153/230 (66.52%), Query Frame = 2 
Query:  149 KLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWL 838
            K CYIINNE FD KL LS R GT +DF+ L     K  F +    NC +  ML+NL++IS R +L +YS+F+C ILSHG + IIYG ++FI+I RLL  FK  +CK L GKPK+F IQAC+G++ D G+ AD   SNNI  +P+E + L+GYSTV  Y SWRN   GSWY+ + C    K    +D++ LLVRVN NV+S FKS +    ++ K+QI SF CML K V+L
Sbjct:   19 KFCYIINNEVFDAKLRLSKRKGTNKDFQNLFDTLTKFEFEIYWANNCRSLEMLQNLKKISLRPDLGEYSIFLCIILSHGSDEIIYGFEDFIEIRRLLHPFKENECKALQGKPKVFIIQACKGNKCDPGVLADDLYSNNIAAVPMELNFLIGYSTVSDYLSWRNEVVGSWYIHSFCEIVRKYGDKEDLLHLLVRVNNNVSSKFKSKSMYTATNDKVQISSFVCMLVKDVYL 248
[Close]
BLAST of Caspase-7 vs. Planmine SMEST
Match: SMESG000053164.1 (SMESG000053164.1)

HSP 1 Score: 211.075 bits (536), Expect = 6.933e-68
Identity = 98/177 (55.37%), Postives = 129/177 (72.88%), Query Frame = 2 
Query:   95 LMDSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYF 625
             MD+VD   +  Y  ++ KLC IINNEEF P+LNL  R GT+ DF  LK++F KL +T +++ N  +  M   L+ +SQR++L + S  V  ILSHG +GIIYG D  +Q+DRL GYFKG+KC+GL+GKPK+FFIQACRG ++DKG+  D   S+NIEKIPIEAD L+GYSTVPG +
Sbjct:   18 FMDNVDGGSSKAYDMSKQKLCVIINNEEFHPQLNLPPRKGTENDFNYLKSVFNKLNYTTDSYTNVISHNMNNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLTDGVHSSNIEKIPIEADFLIGYSTVPGMY 194
[Close]
BLAST of Caspase-7 vs. Planmine SMEST
Match: SMESG000016936.1 (SMESG000016936.1)

HSP 1 Score: 200.675 bits (509), Expect = 1.636e-63
Identity = 101/212 (47.64%), Postives = 133/212 (62.74%), Query Frame = 2 
Query:  122 NNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFK 757
            N  Y  +  K CYIINNE FD KL LS R GT +DF+ L     K  F +    NC +  ML+NL++IS R +L +YS+F+C ILSHG + IIYG ++FI+I RLL  FK  +CK L GKPK+F IQAC+G++ D G+ AD   SNNI  +P+E + L+GYSTV  Y SWRN   GSWY+ + C    K    +D++ LLVR    +    K
Sbjct:   10 NPIYERSGKKFCYIINNEVFDAKLRLSKRKGTNKDFQNLFDTLTKFEFEIYWANNCRSLEMLQNLKKISLRPDLGEYSIFLCIILSHGSDEIIYGFEDFIEIRRLLHPFKENECKALQGKPKVFIIQACKGNKCDPGVLADDLYSNNIAAVPMELNFLIGYSTVSDYLSWRNEVVGSWYIHSFCEIVRKYGDKEDLLHLLVRPIQRITEGIK 221
The following BLAST results are available for this feature:
BLAST of Caspase-7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CASP71.400e-6742.53caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
CASP72.851e-6742.53caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
CASP73.237e-6742.53caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
CASP73.237e-6742.53caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
CASP73.237e-6742.53caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
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BLAST of Caspase-7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ced-37.267e-4133.45Cell death protein 3 Cell death protein 3 subunit ... [more]
ced-32.791e-3933.96Cell death protein 3 Cell death protein 3 subunit ... [more]
csp-16.886e-2627.03Caspase A Caspase A subunit p16 Caspase A subunit ... [more]
csp-11.635e-2427.03Caspase A Caspase A subunit p16 Caspase A subunit ... [more]
csp-21.385e-2129.06Putative inactive caspase B Putative inactive casp... [more]
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BLAST of Caspase-7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dcp-11.602e-5441.18gene:FBgn0010501 transcript:FBtr0072062[more]
Drice3.513e-5437.98gene:FBgn0019972 transcript:FBtr0085482[more]
Decay1.184e-3534.48gene:FBgn0028381 transcript:FBtr0083304[more]
Dronc5.109e-2126.61gene:FBgn0026404 transcript:FBtr0076347[more]
Strica1.388e-1830.30gene:FBgn0033051 transcript:FBtr0335289[more]
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BLAST of Caspase-7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
casp3b3.246e-6842.46caspase 3, apoptosis-related cysteine peptidase b ... [more]
casp72.912e-6646.19caspase 7, apoptosis-related cysteine peptidase [S... [more]
casp3a3.567e-6040.09caspase 3, apoptosis-related cysteine peptidase a ... [more]
casp3a3.567e-6040.09caspase 3, apoptosis-related cysteine peptidase a ... [more]
casp6b.15.902e-4636.02caspase 6b.1, apoptosis-related cysteine peptidase... [more]
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BLAST of Caspase-7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
casp3.23.633e-6343.64caspase 3, gene 2 [Source:NCBI gene;Acc:100151728][more]
lrrc381.094e-5644.35leucine rich repeat containing 38 [Source:Xenbase;... [more]
ENSXETT00000003846.11.784e-5140.00caspase 3, gene 1 [Source:NCBI gene;Acc:100486222][more]
calb22.430e-4436.93calbindin 2 [Source:Xenbase;Acc:XB-GENE-960001][more]
bmt22.500e-3435.12base methyltransferase of 25S rRNA 2 homolog [Sour... [more]
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BLAST of Caspase-7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Casp72.488e-6544.21caspase 7 [Source:MGI Symbol;Acc:MGI:109383][more]
Casp31.905e-6442.28caspase 3 [Source:MGI Symbol;Acc:MGI:107739][more]
Casp31.905e-6442.28caspase 3 [Source:MGI Symbol;Acc:MGI:107739][more]
Casp75.561e-4847.37caspase 7 [Source:MGI Symbol;Acc:MGI:109383][more]
Casp81.587e-4336.30caspase 8 [Source:MGI Symbol;Acc:MGI:1261423][more]
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BLAST of Caspase-7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P55210|CASP7_HUMAN1.555e-6642.53Caspase-7 OS=Homo sapiens OX=9606 GN=CASP7 PE=1 SV... [more]
sp|Q8MJU1|CASP3_FELCA1.029e-6442.35Caspase-3 OS=Felis catus OX=9685 GN=CASP3 PE=2 SV=... [more]
sp|Q60431|CASP3_MESAU1.223e-6442.35Caspase-3 OS=Mesocricetus auratus OX=10036 GN=CASP... [more]
sp|P97864|CASP7_MOUSE1.741e-6444.21Caspase-7 OS=Mus musculus OX=10090 GN=Casp7 PE=1 S... [more]
sp|Q8MKI5|CASP3_CANLF3.763e-6443.02Caspase-3 OS=Canis lupus familiaris OX=9615 GN=CAS... [more]
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BLAST of Caspase-7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Y6I1G11.300e-14176.71Caspase-7 OS=Dugesia japonica OX=6161 GN=cas-7 PE=... [more]
A0A493QY722.059e-14176.71Caspase-7 OS=Dugesia japonica OX=6161 GN=CASP-7 PE... [more]
A0A4Y6I1H46.926e-11362.35Caspase-3B OS=Dugesia japonica OX=6161 GN=cas-3B P... [more]
A0A4Y6I1I13.061e-10057.66Caspase-3A OS=Dugesia japonica OX=6161 GN=cas-3A P... [more]
A0A4Y6I0S15.708e-7851.69Caspase-3C OS=Dugesia japonica OX=6161 GN=cas-3C P... [more]
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BLAST of Caspase-7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
casp72.704e-6747.03caspase 7 [Source:NCBI gene;Acc:103041716][more]
casp72.704e-6747.03caspase 7 [Source:NCBI gene;Acc:103041716][more]
casp3b1.519e-6142.79caspase-3 [Source:NCBI gene;Acc:103025383][more]
casp3b8.342e-5842.98caspase-3 [Source:NCBI gene;Acc:103025383][more]
ENSAMXT00000034295.15.239e-5739.91pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Caspase-7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000005841.19.054e-6441.37pep scaffold:Pmarinus_7.0:GL476535:290070:293064:-... [more]
ENSPMAT00000005440.12.268e-5840.34pep scaffold:Pmarinus_7.0:GL480504:970:21443:-1 ge... [more]
ENSPMAT00000005498.19.228e-4338.34pep scaffold:Pmarinus_7.0:GL481204:7525:20312:1 ge... [more]
ENSPMAT00000008527.11.276e-3045.76pep scaffold:Pmarinus_7.0:GL477443:35181:37755:1 g... [more]
casp3a4.087e-2746.61caspase 3, apoptosis-related cysteine peptidase a ... [more]
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BLAST of Caspase-7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Caspase-7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO418322.917e-5341.35Caspase [Source:UniProtKB/TrEMBL;Acc:A7S364][more]
EDO344606.673e-5241.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412636.639e-5040.87Caspase [Source:UniProtKB/TrEMBL;Acc:A7S4V9][more]
EDO318553.349e-4238.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO425643.349e-4238.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Caspase-7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
casp72.146e-7047.88caspase 7 [Source:NCBI gene;Acc:101161677][more]
casp74.053e-7047.88caspase 7 [Source:NCBI gene;Acc:101161677][more]
casp31.542e-6444.54caspase 3 [Source:NCBI gene;Acc:100049215][more]
casp31.567e-6444.54caspase 3 [Source:NCBI gene;Acc:100049215][more]
casp3a1.674e-6142.79caspase 3B [Source:NCBI gene;Acc:100049265][more]
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BLAST of Caspase-7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053168.10.000e+098.41SMESG000053168.1[more]
SMESG000053166.15.351e-10557.72SMESG000053166.1[more]
SMESG000016936.12.908e-7650.87SMESG000016936.1[more]
SMESG000053164.16.933e-6855.37SMESG000053164.1[more]
SMESG000016936.11.636e-6347.64SMESG000016936.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029698 ID=SMED30029698|Name=Caspase-7|organism=Schmidtea mediterranea sexual|type=transcript|length=952bp
GTTTGTTTTAATTAATCAAAAAATTTTTATTTGCGAATTTTAGTTTAAAT
TATCGAAGTAGTATAAATTTTAATATAACTTAGAAATAAATAAACTTATG
GATTCTGTCGATTCAAAAGAAAACAATGATTATTTTACTAATGAAAACAA
ACTTTGCTATATTATTAATAATGAAGAATTTGATCCTAAATTGAATTTAT
CAGTTCGCTCTGGAACTCAAAGGGATTTTGAAAAATTGAAAGCGTTATTT
AGGAAACTAGGTTTTACTGTCGAAAATCACAAAAATTGCACGGCAGATAT
GATGCTCAAAAATCTTGAAGAAATATCCCAACGGAAAAATCTTAAAGACT
ACTCGATGTTTGTCTGCTTTATTTTATCGCATGGAGATGAAGGTATCATC
TACGGAAGAGATAATTTTATTCAAATCGATAGACTTTTGGGATATTTCAA
AGGCGAGAAATGTAAAGGTCTTGTTGGAAAACCTAAATTGTTTTTCATTC
AAGCCTGTCGTGGTGACAGATTCGATAAAGGAATTTTTGCTGATGCTGGC
GACTCGAATAATATAGAAAAGATTCCAATTGAAGCTGATATTTTGGTTGG
ATACTCTACAGTACCAGGATATTTCTCGTGGCGTAATAGCTCCAACGGCA
GTTGGTATGTCCAAGCGCTTTGCAACGAATTCGAGAAGAATGCTAAAAGT
GATGATGTTGTGTCGCTTCTGGTGAGGGTCAATGCAAATGTTGCCTCAAA
TTTCAAATCCAATACCGGGGAGAAACAGAGTCATGGGAAGCTCCAGATTC
CTTCCTTTACATGTATGTTGCGTAAACGAGTCTGGCTTATAGAAGACCAC
AAATAGAATTTTGTATGGGAATTTTATAACTTCCACACATATATGATTCA
TATTACTGATGTTTTGAAATAAATAAATTAGAGTTTTTTTGTGAAAAAAA
AA
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protein sequence of SMED30029698-orf-1

>SMED30029698-orf-1 ID=SMED30029698-orf-1|Name=SMED30029698-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=253bp
MDSVDSKENNDYFTNENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKAL
FRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGI
IYGRDNFIQIDRLLGYFKGEKCKGLVGKPKLFFIQACRGDRFDKGIFADA
GDSNNIEKIPIEADILVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAK
SDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLIED
HK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR002398Pept_C14
IPR015471Casp7
IPR015917Pept_C14A
IPR029030Caspase-like_dom_sf
IPR033139Caspase_cys_AS
IPR002138Pept_C14_p10
IPR001309Pept_C14_p20
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0004197cysteine-type endopeptidase activity
GO:0005515protein binding
GO:0008233peptidase activity
GO:0016787hydrolase activity
GO:0097200cysteine-type endopeptidase activity involved in execution phase of apoptosis
Vocabulary: biological process
TermDefinition
GO:0006915apoptotic process
GO:0006508proteolysis
GO:0008635activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0097194execution phase of apoptosis
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005737cytoplasm
GO:0005829cytosol
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015917Peptidase C14A, caspase catalytic domainPRINTSPR00376IL1BCENZYMEcoord: 16..29
score: 41.13
coord: 177..188
score: 53.79
coord: 37..55
score: 41.47
coord: 88..96
score: 55.89
coord: 55..73
score: 31.1
coord: 122..140
score: 68.58
IPR015917Peptidase C14A, caspase catalytic domainSMARTSM00115caspase_2coord: 11..249
e-value: 6.1E-93
score: 324.7
IPR015917Peptidase C14A, caspase catalytic domainCDDcd00032CASccoord: 12..247
e-value: 2.11704E-93
score: 272.937
NoneNo IPR availablePFAMPF00656Peptidase_C14coord: 18..244
e-value: 1.0E-48
score: 166.5
NoneNo IPR availableGENE3DG3DSA:3.40.50.1460coord: 2..252
e-value: 9.0E-90
score: 301.9
IPR002398Peptidase C14 familyPANTHERPTHR10454CASPASEcoord: 20..246
IPR015471Caspase-7PANTHERPTHR10454:SF31CASPASE-7coord: 20..246
IPR033139Peptidase family C14A, cysteine active sitePROSITEPS01122CASPASE_CYScoord: 128..139
IPR001309Peptidase C14, p20 domainPROSITEPS50208CASPASE_P20coord: 16..141
score: 45.18
IPR002138Peptidase C14, caspase non-catalytic subunit p10PROSITEPS50207CASPASE_P10coord: 155..249
score: 31.73
IPR029030Caspase-like domain superfamilySUPERFAMILYSSF52129Caspase-likecoord: 16..247