SMED30029683
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30029683 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 58
Homology
BLAST of SMED30029683 vs. Ensembl Human
Match: ITPR3 (inositol 1,4,5-trisphosphate receptor type 3 [Source:HGNC Symbol;Acc:HGNC:6182]) HSP 1 Score: 213.772 bits (543), Expect = 2.962e-54 Identity = 344/1569 (21.92%), Postives = 650/1569 (41.43%), Query Frame = -3
Query: 4889 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIED-ENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN-------------------------------VILVKESRDPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALK---DKEYKR------QQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIA-GIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKV------------HL--ECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL-------TERGQNIHEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKD-----LVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID---------------GSRDLPFPPERQGKELSK---EKKKIV----------QKYQQGDRY-LQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSD-------------------------------------EQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDH--VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH-------------YLTQYILESPHELVYYLLTKPFPKH---LKTHLT 9013
IGD + LY E + +G++ ST ++ + N P D F++ NRY K+Y + +D E + D L + + AA+ E N E ++ V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + I P +K++S G+ V + D++IL + + G HAS + L + E+N + + I D E ++GG V+LFH E E ++ D ++ + +R + +A + +SN+ W++E G W+ +RF+H T YLA +E + ++ V D ++F+L P +Q ++ V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A ++K+ FI+ F+ LLED + F + V + + + M+ K + RQKL+R ++ + +L P + E +++ H+ CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + E Q+ HE +I Y + +W ++ + Q G +D+ + + QL LF +C R I I++ L + FL + E+LP D+RA +C +++ + VD + +V + + ++ + T K S+ A++D + D++ + E + E N L +V+ L + L+ FG+Y ++ L L+G+ID G +++ + G +S +K+ V + DR + E ++ K LE+LQ ILN + R++ ++ FK+ E E + + + +G P +A + ++ MF + ++ +++D +LI+L + YA + AL++L +S +Q+ + +L++ ++ + ++ LR M + W D E ++ I L + C + E+ QR+L + + V++++L + + D+++ E T + L+K P Q + ++L + L L+E+E T++ +F+NN LC +I + V L A H + ++LD L ++K E G +K+ Q ++M + + +S A++L+ R+ V EDH + Y ISL++LL+ CAEG+N Y E C ++L +ED+++V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L + + + PF ++ L+TH T
Sbjct: 10 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADV---VLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHAS-NYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTC-----DEYKGKLQVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAAGMGAQGRTGRRNAGEKIKYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNE------GFISQNDRRFVIQLLEDLV---FFVSD----VPNNGQNVLDIMVT--KPNRERQKLMREQNILKQVFGILKAPFREKGGEGPLVRLEELSDQKNAPYQHMFRLCYRVL-RHSQEDYRKNQEHIAKQFGMMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQS-HEYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQLGV---DLIFLCMADEMLPFDLRASFCHLMLHVHVD-RDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFANTMEFVEDYLNNVVSEAVPF--ANEEKNKLTFEVVSLAHNLIYFGFYS-FSELLRLTRTLLGIIDCVQGPPAMLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDSGA-------DGTAPAFDSTTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVEAGAAKDKKERPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGV---GEQMRKKQQRLLKNMDAHKVMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGN-------PGNQALLHKHLHLFLTPGLLEAE---TMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHV-QYLDFLHTVIKAE--GKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGV------EDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFTLDMARVCSKREKRVADPTLEKYVLSVVLDTINAFFSSPFSENSTSLQTHQT 1496 HSP 2 Score: 133.265 bits (334), Expect = 6.354e-30 Identity = 134/566 (23.67%), Postives = 249/566 (43.99%), Query Frame = -3
Query: 1007 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHN---VLCGFLLFTYFLADHPSPPRI------QYYFILIKRRLK-QNELDPADEDIIQQ---GDEGCKMRSH---LISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR-----------------------------------------SGFNTEKNL-----------YCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEK 2476
+ EE K + ++ +K+ DF D S + N++ +Q+K + P+ +F+ LW GS +FN++ + N + FF P E + + L+ +L F + F + P I Y++ I L L+ ++ + G+ G +R + ++ + Y+ + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + SG + + L CD+L C V+VM GL VGD+ P E F V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I L L + L++H ++ +E K E + ++R +++ GF+ + + +
Sbjct: 2147 LTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLW------------------------GSI--SFNLAVFINIIIAFFY-------PYMEGASTGVLDSPLISLLFWILICFSIAALFTKRYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPNNHSTASPLGMPHGAAAFVDTCSGDKMDCVSGLSVPEVLEEDRELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRK--PSKDES---LFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELK---EQMTEQRKRRQRLGFVDVQNCISR 2671
BLAST of SMED30029683 vs. Ensembl Human
Match: ITPR3 (inositol 1,4,5-trisphosphate receptor type 3 [Source:HGNC Symbol;Acc:HGNC:6182]) HSP 1 Score: 213.772 bits (543), Expect = 2.962e-54 Identity = 344/1569 (21.92%), Postives = 650/1569 (41.43%), Query Frame = -3
Query: 4889 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIED-ENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN-------------------------------VILVKESRDPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALK---DKEYKR------QQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIA-GIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKV------------HL--ECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL-------TERGQNIHEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKD-----LVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID---------------GSRDLPFPPERQGKELSK---EKKKIV----------QKYQQGDRY-LQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSD-------------------------------------EQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDH--VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH-------------YLTQYILESPHELVYYLLTKPFPKH---LKTHLT 9013
IGD + LY E + +G++ ST ++ + N P D F++ NRY K+Y + +D E + D L + + AA+ E N E ++ V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + I P +K++S G+ V + D++IL + + G HAS + L + E+N + + I D E ++GG V+LFH E E ++ D ++ + +R + +A + +SN+ W++E G W+ +RF+H T YLA +E + ++ V D ++F+L P +Q ++ V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A ++K+ FI+ F+ LLED + F + V + + + M+ K + RQKL+R ++ + +L P + E +++ H+ CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + E Q+ HE +I Y + +W ++ + Q G +D+ + + QL LF +C R I I++ L + FL + E+LP D+RA +C +++ + VD + +V + + ++ + T K S+ A++D + D++ + E + E N L +V+ L + L+ FG+Y ++ L L+G+ID G +++ + G +S +K+ V + DR + E ++ K LE+LQ ILN + R++ ++ FK+ E E + + + +G P +A + ++ MF + ++ +++D +LI+L + YA + AL++L +S +Q+ + +L++ ++ + ++ LR M + W D E ++ I L + C + E+ QR+L + + V++++L + + D+++ E T + L+K P Q + ++L + L L+E+E T++ +F+NN LC +I + V L A H + ++LD L ++K E G +K+ Q ++M + + +S A++L+ R+ V EDH + Y ISL++LL+ CAEG+N Y E C ++L +ED+++V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L + + + PF ++ L+TH T
Sbjct: 10 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADV---VLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHAS-NYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTC-----DEYKGKLQVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAAGMGAQGRTGRRNAGEKIKYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNE------GFISQNDRRFVIQLLEDLV---FFVSD----VPNNGQNVLDIMVT--KPNRERQKLMREQNILKQVFGILKAPFREKGGEGPLVRLEELSDQKNAPYQHMFRLCYRVL-RHSQEDYRKNQEHIAKQFGMMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQS-HEYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQLGV---DLIFLCMADEMLPFDLRASFCHLMLHVHVD-RDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFANTMEFVEDYLNNVVSEAVPF--ANEEKNKLTFEVVSLAHNLIYFGFYS-FSELLRLTRTLLGIIDCVQGPPAMLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDSGA-------DGTAPAFDSTTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVEAGAAKDKKERPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGV---GEQMRKKQQRLLKNMDAHKVMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGN-------PGNQALLHKHLHLFLTPGLLEAE---TMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHV-QYLDFLHTVIKAE--GKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGV------EDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFTLDMARVCSKREKRVADPTLEKYVLSVVLDTINAFFSSPFSENSTSLQTHQT 1496 HSP 2 Score: 133.265 bits (334), Expect = 6.354e-30 Identity = 134/566 (23.67%), Postives = 249/566 (43.99%), Query Frame = -3
Query: 1007 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHN---VLCGFLLFTYFLADHPSPPRI------QYYFILIKRRLK-QNELDPADEDIIQQ---GDEGCKMRSH---LISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR-----------------------------------------SGFNTEKNL-----------YCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEK 2476
+ EE K + ++ +K+ DF D S + N++ +Q+K + P+ +F+ LW GS +FN++ + N + FF P E + + L+ +L F + F + P I Y++ I L L+ ++ + G+ G +R + ++ + Y+ + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + SG + + L CD+L C V+VM GL VGD+ P E F V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I L L + L++H ++ +E K E + ++R +++ GF+ + + +
Sbjct: 2147 LTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLW------------------------GSI--SFNLAVFINIIIAFFY-------PYMEGASTGVLDSPLISLLFWILICFSIAALFTKRYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPNNHSTASPLGMPHGAAAFVDTCSGDKMDCVSGLSVPEVLEEDRELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRK--PSKDES---LFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELK---EQMTEQRKRRQRLGFVDVQNCISR 2671
BLAST of SMED30029683 vs. Ensembl Human
Match: ITPR2 (inositol 1,4,5-trisphosphate receptor type 2 [Source:HGNC Symbol;Acc:HGNC:6181]) HSP 1 Score: 207.223 bits (526), Expect = 2.654e-52 Identity = 345/1530 (22.55%), Postives = 612/1530 (40.00%), Query Frame = -3
Query: 4997 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAV----------DEESNV----------------------ILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK-----DKE----YKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVH--------------LECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHE----QPNILYVSTDCMKSWI------------ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG---------------DV--DDVRSLLDKLIGLIDGSRDLPFPPERQGKELSK--------------EKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMA----KFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELRE-MFENTTQ---VKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W------------SDEQVNRME------NIFSE------------------------LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSS--------AAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNL 9013
IGD + LY E + +G++ ST ++ + H + N P D F++ NRY K+Y K + N +A L + + AAE E N +E ++ + V+Y VIQL + S+KY+ VN + +KN M VSL+ ++ + F I P +K++SEG+ + + D+++L + + G HAS LDN E+N + + I + E ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W+IE G W+ FRF+H T YLA +E NV + V D ++F+L + V SY R+ H+ + W+ + D+E K T ED+ + + E+R +D +D A T++K+ F+ LLED + F A V +E+ + ++ K + RQKL+R ++ + +L P + E + L++ CY +L + RKN Y AK + ++Q+ + I L+ +NRK++++ I+ +I FV LR N R+L+ L LCV N I Q I + L + + + ++ + +IL D + W+ A+ Q G D E + + QL+LF +C R I I+ LS + + E LP D+RA +C +++ + VD SVV + P + ++EY D ++ D+ F +++ +L E N E N L +V+ L L+ FG+Y D+ + S ++L DG ++ G+ +++ + + +QG E +++ K +E+LQ IL+ + R++ ++ +F E N +P +L PSA+ I E MF + V++D +LI+L + Y + AL++L +S + + QA + +L++ ++++ + LR+ + W + QV E NI S LI L ++ +QR+L + VV+++L + + D ++ E V+ A L+ P Q + ++L++ L L+E+E T++ +F+NN +LC +I R + V H + E+L L IVK + G +K+ Q +VM ++ A++ + M E +E G + Y I+L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ ++ Y+ +E EI IW+ N
Sbjct: 11 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVHPEAGDLANPPKKFRD---CLFKVCPMNRYSAQKQYW-KAKQAKQGNHTEA---ALLKKLQHAAELEQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNA-GQPLHASNIELLDN-PGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVVRLFHAEQEKFLTC-----DEYEKKQHIFLRTTLRQSA-TSATSSKAL--WEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGVPPTSKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTCQTKEDKEAFAIVSVPLSEVRDLDFANDANKVLATTVKKL-----ENGTITQNERRFVTKLLEDLI---FFVAD----VPNNGQEVLDVVIT--KPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVL-RHSQQDYRKNQEYIAKNFCVMQSQI----GYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKVVSMQADNPMESSILSDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAKEGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSV---DLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRN---------DMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVPPSIHPSKQGSP--TEHEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETSASGSPDTLL-------------PSAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSNYENGEIGESQVKGGEEPIEESNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNE-------VMNLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAE---TMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHV-EYLRFLQTIVKAD--GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGP--LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYV-----DTEVEMKEIYTSNHIWKLFENF 1454 HSP 2 Score: 177.178 bits (448), Expect = 3.801e-43 Identity = 143/582 (24.57%), Postives = 259/582 (44.50%), Query Frame = -3
Query: 1025 KAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDG---SFDENFNI-----SKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-------------------------------------------NTEKNLY-------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 2575
+A K+Y ++ IE+++ D ++++ F + N + E K V +R +K+ DF ++ + N++++QKK NNP +F+ LW L+V +NL + + DG + F++ S+ FF PV ++ ++ + L G L +I + + R G R+ ++ Y+ A + + G + +F++F L ++V+ + L VI +VT+NG+S+I A+L ++++YL++IIGF F + F NT Y CD+L C V+V+ GL VGD+ P E F+ V+Y L F+ ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ +EHNMW Y++F + ++ +YT + +VA ++ E+ D+FP RA+ L + + DS ++I L + + + ++ K + +E + ++R K+ GFL +
Sbjct: 2137 EALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAICTSMLFFFSKPV--------GIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNR----------------GTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGSHQVPTMTLTTMMEACAKENCSPTIPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRR--PSKDEP---LFAARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGDSEQNEIRSLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGS 2689
BLAST of SMED30029683 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]) HSP 1 Score: 160.614 bits (405), Expect = 3.030e-39 Identity = 95/360 (26.39%), Postives = 171/360 (47.50%), Query Frame = -3
Query: 1025 RSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE-----------------------------------------------------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 1930
R+ ++ + Y+ L G + +F++ L ++V+ + L VI +VT+NG+S+I A+L ++++YL++I+G+ FF+ F E K C++L C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+ F + ++ + +YT + +VA ++KE+ D+FP RA+ L + D + +++ L + + + + + + ++ + ++R QK+ G L +
Sbjct: 355 RAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGH 709 HSP 2 Score: 106.686 bits (265), Expect = 3.052e-22 Identity = 95/327 (29.05%), Postives = 156/327 (47.71%), Query Frame = -3
Query: 8048 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVD 9013
IGD LY E T+G++ ST ++ + + N P D F++ NRY K++ K A + DA L ++ AA+ E N E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D + ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA +
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRD---CLFKLCPMNRYSAQKQFW-KAAKPGANSTTDA---VLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTC-----DEHRKKQHVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAE 317
BLAST of SMED30029683 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]) HSP 1 Score: 161.77 bits (408), Expect = 1.024e-38 Identity = 95/360 (26.39%), Postives = 171/360 (47.50%), Query Frame = -3
Query: 1025 RSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE-----------------------------------------------------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 1930
R+ ++ + Y+ L G + +F++ L ++V+ + L VI +VT+NG+S+I A+L ++++YL++I+G+ FF+ F E K C++L C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+ F + ++ + +YT + +VA ++KE+ D+FP RA+ L + D + +++ L + + + + + + ++ + ++R QK+ G L +
Sbjct: 1182 RAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGH 1536 HSP 2 Score: 71.2478 bits (173), Expect = 4.097e-11 Identity = 67/265 (25.28%), Postives = 118/265 (44.53%), Query Frame = -3
Query: 4898 QNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPFPKHLKT 5617
QNQ + +++++ L ++E A+T++ +F+NN LC +I R + V H + +++ L IVK EG +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L +Y+ E +V + PF T
Sbjct: 38 QNQALLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNV-QYIKFLQTIVKAEGK--FIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDEN---SPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTT 288
BLAST of SMED30029683 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 150.599 bits (379), Expect = 1.547e-35 Identity = 89/334 (26.65%), Postives = 163/334 (48.80%), Query Frame = -3
Query: 1076 SHLISSKTFYYFAILGF-SLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR-------------------SGFNTE----------------------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEE 1927
+ +++ + +Y + F + G P + L +I+ + LQ VI++VT+N +S++W +L ++++Y ++I+GF +FR SG +E K C++LW C + GL +GD+ N P + F V Y ++FF+++ I LN+IFG+I+DTF +LR K E +++ CFIC + F++ FE H EHN+W Y+++ + LQ ++T + +VA +K++ D+FP +AL L + D+ S++ ++ L + TL+ S++ E + F E
Sbjct: 2524 AEILACRNLHYLLVYLFICILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWED-----MFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQLLQMMTLMREIISQNEESRAFME 2852 HSP 2 Score: 115.546 bits (288), Expect = 6.374e-25 Identity = 207/952 (21.74%), Postives = 374/952 (39.29%), Query Frame = -3
Query: 6533 IGDFICLYCE-----ETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIE-DENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIIL----ESIKSPGHF---FHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEP-FVRGGQFVQLFHKEMEAYIVAEGLF-DDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILVKESRDPRTVF------KLHPVIQDSEE-----------VTFESYARIEHVLSGNWLHAL-----------------------KDKEYKRQQF--------------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRV-------CMAFREIKEFMLVNGKSV------KARQKLLRNLRVIDLLVKLLNM------------PLYGQPDEAN------FLKVHLECYDILYTYMIGSSRKNALYFA-KYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKV-QINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGY-----DDEKVQFLLAQLDLFNAICYGRNEYCI-----RLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDH-------PERSFV--YEYVGTK---DQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG 9013
IGD I LY E E G+ +ST ++ I +D S + F++ NRY K + + +++ D D L ++ K AA+ E +N +E ++ ++YG ++QL V S+KYI V +++++N M V L+ ++ + F I P YK + G+ V ++I L S GH H S F L + +E+N E + + + + FDE++ V+ G V+LFH + + ++ + + + T+ V LR+ N + + S+ W+++ + + G W++ +RF+H T MYL+ E + + VK + + R K P+++ + VT ES + + W+ +KE R+ + + +++++H + KV C +R + + + V P+ R +F LRN ++ +K + +KE+ C+ F L + + + RQKLLR V++ + LL PL P E + F + CY L Y S RKN + A K+ E+ E D L + ++ +N K++++ K + +FVE +R N ++L+ L LCVC G Q I L R +++ + + + W + L G D E + + QLDL + +C + I R + L E + LP D+R + +++ L V G+ S + H PE V YE V + D ++ + A K L T+ L ++E + +SK+ + +++ L L +F +Y
Sbjct: 39 IGDIISLYTESSSNQEQRGF---LSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD---LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLS-SFNLLDHQSAAEVNCLNEPTEWQVFM-FLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMT-----NRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSA--EPSQVQVKPAMNGRPPLLSALSQKSRPMLERTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIK-LIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCY-CLLKYSQVSYRKNQEFLAEKFGEIQEQIGFD-----LMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTY-----EIVNLAKALAQFNFYS 952 HSP 3 Score: 54.6842 bits (130), Expect = 1.623e-6 Identity = 73/302 (24.17%), Postives = 136/302 (45.03%), Query Frame = -3
Query: 4976 LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENL-------DMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAA--YILEQPMETREAVLKEEL--------GEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYL 5830
L C+ P+ P MNQ++L + V VV+E +SV D + K++ + + L++ + Q+++++ + + +LRV+ +E TL +F NN+ L + I IV L EH + P FL+LL A+V V ++ Q V I + Y+ E EA++K+E ++Y I L+ LL+ C G+N E C + + ++ I+ V+ + +K +L+ L+ Y+ +++ + K + + + NL E+I L
Sbjct: 1278 LTGMCYRKGDPK-PDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMM---KLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE--VGTLVAIFRNNRELASNVPEELIAHIVGLI-EHNSRNPIFLELLQALVCV--YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYI-----DTDAEMKDAYKTEYVDHILNNLLEDIRSL 1565
BLAST of SMED30029683 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 150.599 bits (379), Expect = 1.685e-35 Identity = 89/334 (26.65%), Postives = 163/334 (48.80%), Query Frame = -3
Query: 1076 SHLISSKTFYYFAILGF-SLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR-------------------SGFNTE----------------------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEE 1927
+ +++ + +Y + F + G P + L +I+ + LQ VI++VT+N +S++W +L ++++Y ++I+GF +FR SG +E K C++LW C + GL +GD+ N P + F V Y ++FF+++ I LN+IFG+I+DTF +LR K E +++ CFIC + F++ FE H EHN+W Y+++ + LQ ++T + +VA +K++ D+FP +AL L + D+ S++ ++ L + TL+ S++ E + F E
Sbjct: 2534 AEILACRNLHYLLVYLFICILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWED-----MFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQLLQMMTLMREIISQNEESRAFME 2862 HSP 2 Score: 127.872 bits (320), Expect = 1.233e-28 Identity = 212/952 (22.27%), Postives = 374/952 (39.29%), Query Frame = -3
Query: 6533 IGDFICLYCE-----ETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIE-DENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIIL----ESIKSPGHF---FHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEP-FVRGGQFVQLFHKEMEAYIVAEGLF-DDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVD-------------------EESNVILVKESRDPRTV---------------------------------FKLHP--VIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRV-------CMAFREIKEFMLVNGKSV------KARQKLLRNLRVIDLLVKLLNM------------PLYGQPDEAN------FLKVHLECYDILYTYMIGSSRKNALYFA-KYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKV-QINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGY-----DDEKVQFLLAQLDLFNAICYGRNEYCI-----RLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDH-------PERSFV--YEYVGTK---DQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG 9013
IGD I LY E E G+ +ST ++ I +D S + F++ NRY K + + +++ D D L ++ K AA+ E +N +E ++ ++YG ++QL V S+KYI V +++++N M V L+ ++ + F I P YK + G+ V ++I L S GH H S F L + +E+N E + + + + FDE++ V+ G V+LFH + + ++ + + + T+ V LR+ N + + S+ W+++ + + G W++ +RF+H T MYL+ + ++N + S P V F+L P ++ ++EV SY R+ H S W+HA E + +S+ ++ W KV C +R + + + V P+ R +F LRN ++ +K + +KE+ C+ F L + + + RQKLLR V++ + LL PL P E + F + CY L Y S RKN + A K+ E+ E D L + ++ +N K++++ K + +FVE +R N ++L+ L LCVC G Q I L R +++ + + + W + L G D E + + QLDL + +C + I R + L E + LP D+R + +++ L V G+ S + H PE V YE V + D ++ + A K L T+ L ++E + +SK+ + +++ L L +F +Y
Sbjct: 39 IGDIISLYTESSSNQEQRGF---LSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD---LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLS-SFNLLDHQSAAEVNCLNEPTEWQVFM-FLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMT-----NRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEK------GW-----VKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIK-LIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCY-CLLKYSQVSYRKNQEFLAEKFGEIQEQIGFD-----LMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTY-----EIVNLAKALAQFNFYS 943 HSP 3 Score: 54.6842 bits (130), Expect = 1.583e-6 Identity = 73/302 (24.17%), Postives = 136/302 (45.03%), Query Frame = -3
Query: 4976 LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENL-------DMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAA--YILEQPMETREAVLKEEL--------GEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYL 5830
L C+ P+ P MNQ++L + V VV+E +SV D + K++ + + L++ + Q+++++ + + +LRV+ +E TL +F NN+ L + I IV L EH + P FL+LL A+V V ++ Q V I + Y+ E EA++K+E ++Y I L+ LL+ C G+N E C + + ++ I+ V+ + +K +L+ L+ Y+ +++ + K + + + NL E+I L
Sbjct: 1269 LTGMCYRKGDPK-PDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMM---KLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE--VGTLVAIFRNNRELASNVPEELIAHIVGLI-EHNSRNPIFLELLQALVCV--YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYI-----DTDAEMKDAYKTEYVDHILNNLLEDIRSL 1556
BLAST of SMED30029683 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 150.599 bits (379), Expect = 1.693e-35 Identity = 89/334 (26.65%), Postives = 163/334 (48.80%), Query Frame = -3
Query: 1076 SHLISSKTFYYFAILGF-SLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR-------------------SGFNTE----------------------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEE 1927
+ +++ + +Y + F + G P + L +I+ + LQ VI++VT+N +S++W +L ++++Y ++I+GF +FR SG +E K C++LW C + GL +GD+ N P + F V Y ++FF+++ I LN+IFG+I+DTF +LR K E +++ CFIC + F++ FE H EHN+W Y+++ + LQ ++T + +VA +K++ D+FP +AL L + D+ S++ ++ L + TL+ S++ E + F E
Sbjct: 2503 AEILACRNLHYLLVYLFICILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWED-----MFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQLLQMMTLMREIISQNEESRAFME 2831 HSP 2 Score: 127.872 bits (320), Expect = 1.169e-28 Identity = 212/952 (22.27%), Postives = 374/952 (39.29%), Query Frame = -3
Query: 6533 IGDFICLYCE-----ETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIE-DENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIIL----ESIKSPGHF---FHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEP-FVRGGQFVQLFHKEMEAYIVAEGLF-DDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVD-------------------EESNVILVKESRDPRTV---------------------------------FKLHP--VIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRV-------CMAFREIKEFMLVNGKSV------KARQKLLRNLRVIDLLVKLLNM------------PLYGQPDEAN------FLKVHLECYDILYTYMIGSSRKNALYFA-KYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKV-QINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGY-----DDEKVQFLLAQLDLFNAICYGRNEYCI-----RLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDH-------PERSFV--YEYVGTK---DQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG 9013
IGD I LY E E G+ +ST ++ I +D S + F++ NRY K + + +++ D D L ++ K AA+ E +N +E ++ ++YG ++QL V S+KYI V +++++N M V L+ ++ + F I P YK + G+ V ++I L S GH H S F L + +E+N E + + + + FDE++ V+ G V+LFH + + ++ + + + T+ V LR+ N + + S+ W+++ + + G W++ +RF+H T MYL+ + ++N + S P V F+L P ++ ++EV SY R+ H S W+HA E + +S+ ++ W KV C +R + + + V P+ R +F LRN ++ +K + +KE+ C+ F L + + + RQKLLR V++ + LL PL P E + F + CY L Y S RKN + A K+ E+ E D L + ++ +N K++++ K + +FVE +R N ++L+ L LCVC G Q I L R +++ + + + W + L G D E + + QLDL + +C + I R + L E + LP D+R + +++ L V G+ S + H PE V YE V + D ++ + A K L T+ L ++E + +SK+ + +++ L L +F +Y
Sbjct: 29 IGDIISLYTESSSNQEQRGF---LSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD---LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLS-SFNLLDHQSAAEVNCLNEPTEWQVFM-FLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMT-----NRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEK------GW-----VKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIK-LIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCY-CLLKYSQVSYRKNQEFLAEKFGEIQEQIGFD-----LMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTY-----EIVNLAKALAQFNFYS 933 HSP 3 Score: 54.6842 bits (130), Expect = 1.677e-6 Identity = 73/302 (24.17%), Postives = 136/302 (45.03%), Query Frame = -3
Query: 4976 LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENL-------DMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAA--YILEQPMETREAVLKEEL--------GEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYL 5830
L C+ P+ P MNQ++L + V VV+E +SV D + K++ + + L++ + Q+++++ + + +LRV+ +E TL +F NN+ L + I IV L EH + P FL+LL A+V V ++ Q V I + Y+ E EA++K+E ++Y I L+ LL+ C G+N E C + + ++ I+ V+ + +K +L+ L+ Y+ +++ + K + + + NL E+I L
Sbjct: 1259 LTGMCYRKGDPK-PDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMM---KLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE--VGTLVAIFRNNRELASNVPEELIAHIVGLI-EHNSRNPIFLELLQALVCV--YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYI-----DTDAEMKDAYKTEYVDHILNNLLEDIRSL 1546
BLAST of SMED30029683 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 150.599 bits (379), Expect = 1.703e-35 Identity = 89/334 (26.65%), Postives = 163/334 (48.80%), Query Frame = -3
Query: 1076 SHLISSKTFYYFAILGF-SLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR-------------------SGFNTE----------------------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEE 1927
+ +++ + +Y + F + G P + L +I+ + LQ VI++VT+N +S++W +L ++++Y ++I+GF +FR SG +E K C++LW C + GL +GD+ N P + F V Y ++FF+++ I LN+IFG+I+DTF +LR K E +++ CFIC + F++ FE H EHN+W Y+++ + LQ ++T + +VA +K++ D+FP +AL L + D+ S++ ++ L + TL+ S++ E + F E
Sbjct: 2559 AEILACRNLHYLLVYLFICILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWED-----MFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQLLQMMTLMREIISQNEESRAFME 2887 HSP 2 Score: 127.872 bits (320), Expect = 1.136e-28 Identity = 212/952 (22.27%), Postives = 374/952 (39.29%), Query Frame = -3
Query: 6533 IGDFICLYCE-----ETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIE-DENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIIL----ESIKSPGHF---FHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEP-FVRGGQFVQLFHKEMEAYIVAEGLF-DDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVD-------------------EESNVILVKESRDPRTV---------------------------------FKLHP--VIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRV-------CMAFREIKEFMLVNGKSV------KARQKLLRNLRVIDLLVKLLNM------------PLYGQPDEAN------FLKVHLECYDILYTYMIGSSRKNALYFA-KYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKV-QINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGY-----DDEKVQFLLAQLDLFNAICYGRNEYCI-----RLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDH-------PERSFV--YEYVGTK---DQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG 9013
IGD I LY E E G+ +ST ++ I +D S + F++ NRY K + + +++ D D L ++ K AA+ E +N +E ++ ++YG ++QL V S+KYI V +++++N M V L+ ++ + F I P YK + G+ V ++I L S GH H S F L + +E+N E + + + + FDE++ V+ G V+LFH + + ++ + + + T+ V LR+ N + + S+ W+++ + + G W++ +RF+H T MYL+ + ++N + S P V F+L P ++ ++EV SY R+ H S W+HA E + +S+ ++ W KV C +R + + + V P+ R +F LRN ++ +K + +KE+ C+ F L + + + RQKLLR V++ + LL PL P E + F + CY L Y S RKN + A K+ E+ E D L + ++ +N K++++ K + +FVE +R N ++L+ L LCVC G Q I L R +++ + + + W + L G D E + + QLDL + +C + I R + L E + LP D+R + +++ L V G+ S + H PE V YE V + D ++ + A K L T+ L ++E + +SK+ + +++ L L +F +Y
Sbjct: 85 IGDIISLYTESSSNQEQRGF---LSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD---LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLS-SFNLLDHQSAAEVNCLNEPTEWQVFM-FLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMT-----NRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEK------GW-----VKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIK-LIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCY-CLLKYSQVSYRKNQEFLAEKFGEIQEQIGFD-----LMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTY-----EIVNLAKALAQFNFYS 989 HSP 3 Score: 54.299 bits (129), Expect = 2.125e-6 Identity = 73/302 (24.17%), Postives = 136/302 (45.03%), Query Frame = -3
Query: 4976 LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENL-------DMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAA--YILEQPMETREAVLKEEL--------GEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYL 5830
L C+ P+ P MNQ++L + V VV+E +SV D + K++ + + L++ + Q+++++ + + +LRV+ +E TL +F NN+ L + I IV L EH + P FL+LL A+V V ++ Q V I + Y+ E EA++K+E ++Y I L+ LL+ C G+N E C + + ++ I+ V+ + +K +L+ L+ Y+ +++ + K + + + NL E+I L
Sbjct: 1315 LTGMCYRKGDPK-PDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMM---KLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE--VGTLVAIFRNNRELASNVPEELIAHIVGLI-EHNSRNPIFLELLQALVCV--YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYI-----DTDAEMKDAYKTEYVDHILNNLLEDIRSL 1602
BLAST of SMED30029683 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 150.214 bits (378), Expect = 1.890e-35 Identity = 89/334 (26.65%), Postives = 163/334 (48.80%), Query Frame = -3
Query: 1076 SHLISSKTFYYFAILGF-SLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR-------------------SGFNTE----------------------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEE 1927
+ +++ + +Y + F + G P + L +I+ + LQ VI++VT+N +S++W +L ++++Y ++I+GF +FR SG +E K C++LW C + GL +GD+ N P + F V Y ++FF+++ I LN+IFG+I+DTF +LR K E +++ CFIC + F++ FE H EHN+W Y+++ + LQ ++T + +VA +K++ D+FP +AL L + D+ S++ ++ L + TL+ S++ E + F E
Sbjct: 2513 AEILACRNLHYLLVYLFICILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWED-----MFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQLLQMMTLMREIISQNEESRAFME 2841 HSP 2 Score: 127.872 bits (320), Expect = 1.085e-28 Identity = 212/952 (22.27%), Postives = 374/952 (39.29%), Query Frame = -3
Query: 6533 IGDFICLYCE-----ETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIE-DENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIIL----ESIKSPGHF---FHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEP-FVRGGQFVQLFHKEMEAYIVAEGLF-DDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVD-------------------EESNVILVKESRDPRTV---------------------------------FKLHP--VIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRV-------CMAFREIKEFMLVNGKSV------KARQKLLRNLRVIDLLVKLLNM------------PLYGQPDEAN------FLKVHLECYDILYTYMIGSSRKNALYFA-KYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKV-QINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGY-----DDEKVQFLLAQLDLFNAICYGRNEYCI-----RLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDH-------PERSFV--YEYVGTK---DQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG 9013
IGD I LY E E G+ +ST ++ I +D S + F++ NRY K + + +++ D D L ++ K AA+ E +N +E ++ ++YG ++QL V S+KYI V +++++N M V L+ ++ + F I P YK + G+ V ++I L S GH H S F L + +E+N E + + + + FDE++ V+ G V+LFH + + ++ + + + T+ V LR+ N + + S+ W+++ + + G W++ +RF+H T MYL+ + ++N + S P V F+L P ++ ++EV SY R+ H S W+HA E + +S+ ++ W KV C +R + + + V P+ R +F LRN ++ +K + +KE+ C+ F L + + + RQKLLR V++ + LL PL P E + F + CY L Y S RKN + A K+ E+ E D L + ++ +N K++++ K + +FVE +R N ++L+ L LCVC G Q I L R +++ + + + W + L G D E + + QLDL + +C + I R + L E + LP D+R + +++ L V G+ S + H PE V YE V + D ++ + A K L T+ L ++E + +SK+ + +++ L L +F +Y
Sbjct: 39 IGDIISLYTESSSNQEQRGF---LSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD---LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLS-SFNLLDHQSAAEVNCLNEPTEWQVFM-FLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMT-----NRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEK------GW-----VKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIK-LIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCY-CLLKYSQVSYRKNQEFLAEKFGEIQEQIGFD-----LMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTY-----EIVNLAKALAQFNFYS 943 HSP 3 Score: 54.6842 bits (130), Expect = 1.650e-6 Identity = 73/302 (24.17%), Postives = 136/302 (45.03%), Query Frame = -3
Query: 4976 LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENL-------DMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAA--YILEQPMETREAVLKEEL--------GEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYL 5830
L C+ P+ P MNQ++L + V VV+E +SV D + K++ + + L++ + Q+++++ + + +LRV+ +E TL +F NN+ L + I IV L EH + P FL+LL A+V V ++ Q V I + Y+ E EA++K+E ++Y I L+ LL+ C G+N E C + + ++ I+ V+ + +K +L+ L+ Y+ +++ + K + + + NL E+I L
Sbjct: 1269 LTGMCYRKGDPK-PDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMM---KLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE--VGTLVAIFRNNRELASNVPEELIAHIVGLI-EHNSRNPIFLELLQALVCV--YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYI-----DTDAEMKDAYKTEYVDHILNNLLEDIRSL 1556
BLAST of SMED30029683 vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0078686) HSP 1 Score: 157.532 bits (397), Expect = 1.676e-37 Identity = 131/532 (24.62%), Postives = 238/532 (44.74%), Query Frame = -3
Query: 1070 NVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSL---PDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKT----FYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR----------------------------------------------------SGFNTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDE----------LLKNVSTLINHQKSEDSERKRFEELL 2443
+R +K+ DF D ++ + N++++QKK + P+ + + LW+ + V++N M+ F P D + E +S + + L F + PR +++++ + L F + L P ++ LK + + G++G + LI T Y+ + F G + P+F++ L ++V+ + L VI +VT+NG+S++ A+L ++++YL++IIG+ FF+ +G K CDSL C V+ + GL +GD+ P E F VIY L FF ++ I LN+IFG+I+DTF++LR K E+ ++ TCFICS N F++ FE H+ +EHNMW Y++F + ++ ++T + +V ++K ++FP RA+ L A D D ++ L+KN+ST ++ K +E+++ ++ L
Sbjct: 2313 TAERDDQGSKVADFFDKAEEMFNEMKWQKKLRSQPLLFWISSYMSLWSNILFNCVVVIN--MIVAFFYPFDNTVPE---LSSHISLLFWIITIFSLVIVLALPRESGIRTFIGSV---------ILRFIFLLG----PESTLCLLGVVTVTLKSVHI------VSIMGNKG-TLEKQLIKIITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPSAGGGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRA--PSSKEGLFVAR---VIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQLHELKDHMTEQRKQKQRL 2814 HSP 2 Score: 135.191 bits (339), Expect = 7.875e-31 Identity = 170/717 (23.71%), Postives = 284/717 (39.61%), Query Frame = -3
Query: 7118 IGDFICLYCEETDGYVYS-MSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGE-VIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNV----------------------------------------------ILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQFSTT------EDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKV------YPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPL---------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTN-ENY--RYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL 9013
+GD + LY E G V +ST ++ + + + + +I NRY K++ + N L + AAE E N E ++ ++YG V+QL + S+KY+ VN S +KN M V L+ + ++ + F I P YK++S G+YV + D++IL + + H + + L + E+N+ + + I H + E ++GG V+LFH E E ++ D +Q H+ +R + +A T TS+ A+ W+IE + G W+ +RF+H T YLA + E +V + V S D +VF L + V SY R++H+ S W+HA D + + S ED+ + I E+R +D +D A K+ E + + IV F+ + ++ K K L EF + N ++ RQKLLR ++ L K+L P P + + + CY IL RKN Y AK+ L + Q+ + I L+ +NRK++++ I+ +I FV +R N N+ R+L+ L LCV N I Q I + L + + + +
Sbjct: 14 LGDIVSLYAE---GSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQKQFWKAAKQSASSNT----DPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTM-----DEYKKQYHVFLRTTGRTSA-TAATSSKAL--WEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAMSATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKAL----------------EFTIKN--PIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQ-QDYRKNQEYIAKHFGLMQKQI----GYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILI 692 HSP 3 Score: 65.0846 bits (157), Expect = 1.491e-9 Identity = 93/447 (20.81%), Postives = 183/447 (40.94%), Query Frame = -3
Query: 4916 ILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDE-------------------------QVNRMENIFSELIEFCHLPKAPE---EPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIF--ENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYILEQPMETREAVLK-EELGEDH-VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIW------------QFIGNLGEEIH-YLTQYILESPHELVYYLLTKPF 6076
+L++L + YA + AL +L +S +Q+ QA + +L++ ++++ + +LR K+K +DE + +++ I + +FC P +P QR+L + V VV+++L D + E + L + QNQ+ +LD+ L ++E++ T+ +F +N LC ++ + + V H + +L L +V+ E ++R Q +VM+ ++ S Y+ ++ +L+ E+L +D ++Y + L++LL+ C G+N Y E C +LS++DI+ ++ HP +K ++ +L Y+ +E EI +W Q I N + L Y+L L+ PF
Sbjct: 1158 VLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEKSELWVYKAKATDELGATDAGGDAVSLEYNAALSQEQRNEYRKVKEILIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKE-----LMCLAHEFLQNFCLGNQQNQVLLHNHLDLFLNPGILEAK---TVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVA-YLQFLQTVVRAENQ--FIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYI-----DTEVEMKEIYASGHMWSLFEKSFLVDINQLITNPAAASNKTLQAYVLNGVTNLLGSFFASPF 1588
BLAST of SMED30029683 vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0344265) HSP 1 Score: 157.532 bits (397), Expect = 1.676e-37 Identity = 131/532 (24.62%), Postives = 238/532 (44.74%), Query Frame = -3
Query: 1070 NVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSL---PDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKT----FYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR----------------------------------------------------SGFNTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDE----------LLKNVSTLINHQKSEDSERKRFEELL 2443
+R +K+ DF D ++ + N++++QKK + P+ + + LW+ + V++N M+ F P D + E +S + + L F + PR +++++ + L F + L P ++ LK + + G++G + LI T Y+ + F G + P+F++ L ++V+ + L VI +VT+NG+S++ A+L ++++YL++IIG+ FF+ +G K CDSL C V+ + GL +GD+ P E F VIY L FF ++ I LN+IFG+I+DTF++LR K E+ ++ TCFICS N F++ FE H+ +EHNMW Y++F + ++ ++T + +V ++K ++FP RA+ L A D D ++ L+KN+ST ++ K +E+++ ++ L
Sbjct: 2313 TAERDDQGSKVADFFDKAEEMFNEMKWQKKLRSQPLLFWISSYMSLWSNILFNCVVVIN--MIVAFFYPFDNTVPE---LSSHISLLFWIITIFSLVIVLALPRESGIRTFIGSV---------ILRFIFLLG----PESTLCLLGVVTVTLKSVHI------VSIMGNKG-TLEKQLIKIITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPSAGGGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRA--PSSKEGLFVAR---VIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQLHELKDHMTEQRKQKQRL 2814 HSP 2 Score: 135.191 bits (339), Expect = 7.875e-31 Identity = 170/717 (23.71%), Postives = 284/717 (39.61%), Query Frame = -3
Query: 7118 IGDFICLYCEETDGYVYS-MSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGE-VIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNV----------------------------------------------ILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQFSTT------EDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKV------YPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPL---------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTN-ENY--RYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL 9013
+GD + LY E G V +ST ++ + + + + +I NRY K++ + N L + AAE E N E ++ ++YG V+QL + S+KY+ VN S +KN M V L+ + ++ + F I P YK++S G+YV + D++IL + + H + + L + E+N+ + + I H + E ++GG V+LFH E E ++ D +Q H+ +R + +A T TS+ A+ W+IE + G W+ +RF+H T YLA + E +V + V S D +VF L + V SY R++H+ S W+HA D + + S ED+ + I E+R +D +D A K+ E + + IV F+ + ++ K K L EF + N ++ RQKLLR ++ L K+L P P + + + CY IL RKN Y AK+ L + Q+ + I L+ +NRK++++ I+ +I FV +R N N+ R+L+ L LCV N I Q I + L + + + +
Sbjct: 14 LGDIVSLYAE---GSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQKQFWKAAKQSASSNT----DPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTM-----DEYKKQYHVFLRTTGRTSA-TAATSSKAL--WEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAMSATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKAL----------------EFTIKN--PIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQ-QDYRKNQEYIAKHFGLMQKQI----GYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILI 692 HSP 3 Score: 65.0846 bits (157), Expect = 1.491e-9 Identity = 93/447 (20.81%), Postives = 183/447 (40.94%), Query Frame = -3
Query: 4916 ILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDE-------------------------QVNRMENIFSELIEFCHLPKAPE---EPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIF--ENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYILEQPMETREAVLK-EELGEDH-VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIW------------QFIGNLGEEIH-YLTQYILESPHELVYYLLTKPF 6076
+L++L + YA + AL +L +S +Q+ QA + +L++ ++++ + +LR K+K +DE + +++ I + +FC P +P QR+L + V VV+++L D + E + L + QNQ+ +LD+ L ++E++ T+ +F +N LC ++ + + V H + +L L +V+ E ++R Q +VM+ ++ S Y+ ++ +L+ E+L +D ++Y + L++LL+ C G+N Y E C +LS++DI+ ++ HP +K ++ +L Y+ +E EI +W Q I N + L Y+L L+ PF
Sbjct: 1158 VLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEKSELWVYKAKATDELGATDAGGDAVSLEYNAALSQEQRNEYRKVKEILIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKE-----LMCLAHEFLQNFCLGNQQNQVLLHNHLDLFLNPGILEAK---TVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVA-YLQFLQTVVRAENQ--FIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYI-----DTEVEMKEIYASGHMWSLFEKSFLVDINQLITNPAAASNKTLQAYVLNGVTNLLGSFFASPF 1588
BLAST of SMED30029683 vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0078687) HSP 1 Score: 157.532 bits (397), Expect = 1.677e-37 Identity = 131/532 (24.62%), Postives = 238/532 (44.74%), Query Frame = -3
Query: 1070 NVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSL---PDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKT----FYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR----------------------------------------------------SGFNTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDE----------LLKNVSTLINHQKSEDSERKRFEELL 2443
+R +K+ DF D ++ + N++++QKK + P+ + + LW+ + V++N M+ F P D + E +S + + L F + PR +++++ + L F + L P ++ LK + + G++G + LI T Y+ + F G + P+F++ L ++V+ + L VI +VT+NG+S++ A+L ++++YL++IIG+ FF+ +G K CDSL C V+ + GL +GD+ P E F VIY L FF ++ I LN+IFG+I+DTF++LR K E+ ++ TCFICS N F++ FE H+ +EHNMW Y++F + ++ ++T + +V ++K ++FP RA+ L A D D ++ L+KN+ST ++ K +E+++ ++ L
Sbjct: 2322 TAERDDQGSKVADFFDKAEEMFNEMKWQKKLRSQPLLFWISSYMSLWSNILFNCVVVIN--MIVAFFYPFDNTVPE---LSSHISLLFWIITIFSLVIVLALPRESGIRTFIGSV---------ILRFIFLLG----PESTLCLLGVVTVTLKSVHI------VSIMGNKG-TLEKQLIKIITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPSAGGGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRA--PSSKEGLFVAR---VIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQLHELKDHMTEQRKQKQRL 2823 HSP 2 Score: 135.576 bits (340), Expect = 6.444e-31 Identity = 170/717 (23.71%), Postives = 284/717 (39.61%), Query Frame = -3
Query: 7118 IGDFICLYCEETDGYVYS-MSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGE-VIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNV----------------------------------------------ILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQFSTT------EDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKV------YPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPL---------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTN-ENY--RYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL 9013
+GD + LY E G V +ST ++ + + + + +I NRY K++ + N L + AAE E N E ++ ++YG V+QL + S+KY+ VN S +KN M V L+ + ++ + F I P YK++S G+YV + D++IL + + H + + L + E+N+ + + I H + E ++GG V+LFH E E ++ D +Q H+ +R + +A T TS+ A+ W+IE + G W+ +RF+H T YLA + E +V + V S D +VF L + V SY R++H+ S W+HA D + + S ED+ + I E+R +D +D A K+ E + + IV F+ + ++ K K L EF + N ++ RQKLLR ++ L K+L P P + + + CY IL RKN Y AK+ L + Q+ + I L+ +NRK++++ I+ +I FV +R N N+ R+L+ L LCV N I Q I + L + + + +
Sbjct: 14 LGDIVSLYAE---GSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQKQFWKAAKQSASSNT----DPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTM-----DEYKKQYHVFLRTTGRTSA-TAATSSKAL--WEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAMSATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKAL----------------EFTIKN--PIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQ-QDYRKNQEYIAKHFGLMQKQI----GYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILI 692 HSP 3 Score: 65.0846 bits (157), Expect = 1.407e-9 Identity = 93/447 (20.81%), Postives = 183/447 (40.94%), Query Frame = -3
Query: 4916 ILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDE-------------------------QVNRMENIFSELIEFCHLPKAPE---EPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIF--ENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYILEQPMETREAVLK-EELGEDH-VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIW------------QFIGNLGEEIH-YLTQYILESPHELVYYLLTKPF 6076
+L++L + YA + AL +L +S +Q+ QA + +L++ ++++ + +LR K+K +DE + +++ I + +FC P +P QR+L + V VV+++L D + E + L + QNQ+ +LD+ L ++E++ T+ +F +N LC ++ + + V H + +L L +V+ E ++R Q +VM+ ++ S Y+ ++ +L+ E+L +D ++Y + L++LL+ C G+N Y E C +LS++DI+ ++ HP +K ++ +L Y+ +E EI +W Q I N + L Y+L L+ PF
Sbjct: 1167 VLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEKSELWVYKAKATDELGATDAGGDAVSLEYNAALSQEQRNEYRKVKEILIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKE-----LMCLAHEFLQNFCLGNQQNQVLLHNHLDLFLNPGILEAK---TVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVA-YLQFLQTVVRAENQ--FIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYI-----DTEVEMKEIYASGHMWSLFEKSFLVDINQLITNPAAASNKTLQAYVLNGVTNLLGSFFASPF 1597
BLAST of SMED30029683 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088639) HSP 1 Score: 115.931 bits (289), Expect = 7.569e-25 Identity = 75/249 (30.12%), Postives = 130/249 (52.21%), Query Frame = -3
Query: 1172 TFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWH----CFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDED 1906
+ +YF+ FS+ G ++ +FFA HL+++ + L+ ++ +VT NGK L+ +L +++Y+Y +I F FFR + E++ D H CFV + G+ D + + ++ FF +I + L II G+I+D F ELRD + + +M CFIC F+ GF+ HV EHN+ +Y+FF +HL + +YT + +V + +++ +DFFP+ C + ED
Sbjct: 4863 SLWYFS---FSVMGN-FNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIIL-LAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVGD--CFRKQYED 5104
BLAST of SMED30029683 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0304568) HSP 1 Score: 115.546 bits (288), Expect = 7.762e-25 Identity = 75/249 (30.12%), Postives = 130/249 (52.21%), Query Frame = -3
Query: 1172 TFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWH----CFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDED 1906
+ +YF+ FS+ G ++ +FFA HL+++ + L+ ++ +VT NGK L+ +L +++Y+Y +I F FFR + E++ D H CFV + G+ D + + ++ FF +I + L II G+I+D F ELRD + + +M CFIC F+ GF+ HV EHN+ +Y+FF +HL + +YT + +V + +++ +DFFP+ C + ED
Sbjct: 4867 SLWYFS---FSVMGN-FNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIIL-LAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVGD--CFRKQYED 5108
BLAST of SMED30029683 vs. Ensembl Zebrafish
Match: itpr3 (inositol 1,4,5-trisphosphate receptor, type 3 [Source:ZFIN;Acc:ZDB-GENE-070605-1]) HSP 1 Score: 224.172 bits (570), Expect = 1.143e-57 Identity = 339/1521 (22.29%), Postives = 631/1521 (41.49%), Query Frame = -3
Query: 4997 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLR-KFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVD------EESNVILVKESR--------------------DPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALK---DKEYKR------QQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDR---LKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYD---ILYTYMIG-----------SSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL-TERGQNIHEQPNILYVS--TDCMKSWI------------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITK--DLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSV---------VDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIA----SKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID-----GSRDLPFPPERQGKELSKEKKKIVQKY----------------QQGDRYLQSKET-----SAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W---------------------------------------SDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSY----------SSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNL 9013
IGD + LY E T +G++ ST ++ + N P D F++ NRY K++ + K A E + + D L + + AA E N AE ++ V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + I P +K+++ G+ V + D++IL + + G HAS + L + E+N + + I D + ++GG V+LFH E E ++ D ++H+ +R + +A + +SN+ W++E G W+ +RF+H T YLA + E SN I V SR D ++F+L P +Q ++ V SY R H+ + W+ + D + +R T ED+ + + E+R +D +D + ++K + P + I LLED + ++ + + A V M K + RQKL+R ++ + ++ P + D+ L + E D +LY YM+ RKN Y AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N V I Q I + L + + + TER Q Y+ D + W+ ++ + Q G +D+ + + QL LF +C+ R I +I+K D+ +S L + E LP D+RA +C +++ VD V + P + +Y D ++ +++A AF++E N +I + E N L +V+ L L+ FG+Y ++ L L+G+ID S + F + GK + + + Q + GD + SK++ +++ K LE+LQ IL+ + RL+ ++ FK+ P A A + + + +++ Q + ++ MF + + +++D +LI+L + Y + AL++L +S +Q+ + +L++T ++ + + + LLR M + W S+E ++ I L + C ++ QR+L + V++++L + D + T+ + L +++NQ + ++L++ L +L+E+E T++++F NN LC +I +H + A Q + ++L+ L I+K E G +K+ Q ++M + + +S ++E ++RE V + ++Y ISL+ELL+ CAEG+N Y E C ++L +E+++ V+ H + +K ++ ++ Y+ +E EI IW+ N
Sbjct: 11 IGDIVSLYAEGTVNGFI---STLGLVDDRCVVEPASGDLENPPKKFRD---CLFKVYPMNRYSAQKQFWKAKQAKHEKDKIGDM---VLLQKLQHAANLEQKQNDAENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDGTGNEGSWLFIQPFWKLRANGDNVVVGDKVILNPVNA-GQPLHAS-SYELPDHSGCKEINSVNSNTSWKISLFMMFSDHKDEVLKGGDVVRLFHAEQEKFLTC-----DEYKSKLHVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNSLYRFKHLATGNYLAAEENPGYKENSNDIEVDSSRIKRSLGERIKYKLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRFRHLCTNTWIQSTNIPIDIDEERPIRLMLGTCPTKEDKEAFAIVSVPVMEIRDLDFANDASLMLSTVVEKFKYGFLSPNDRRYAI-----KLLEDVVFFVVDQLNNGQPALEVSM------------NKPNRERQKLMREQNILKQIFGIIKAPFKERGDDPPLLTLE-ELSDQKYLLYQYMLRLCYRVLRHSQEDYRKNQEYIAKQFGMMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNNVAIPVTQELICKCVLNAKNQDILMKTERRAAKESQHTSEYLEEFGDEDEVWLIWSEKENENHEKSIRQLAQEARQGNVHDENVLTYYRYQLKLFARMCFDRQYLAIDVISKQLDIELIS-----LCMMDETLPFDLRASFCRLMLHAHVDRDPQELVTPIKFARLWTEIPTSISIKDYDSHLDYSRDNKKNKFAN-------------TMAFMEEYLNNVLIDDLPFANEEKNKLTYEVVSLARHLIYFGFYS-FFELLRLTRTLLGIIDCTPSNASINPLFNDDGSGKNVRRSIHGMGQMMSTMVLNRKPSLFSAPGRTGDSQVGSKDSIDTQDITVMDTKLKILEILQFILSVRLDYRLSFLLSVFKK------EFVDVYPMEDADATH-----HTEHEASINLQHIG-EQAEAMFGIGKGNSILEVDDEGGRMFLRVLIHLIMHDYPPLVSGALQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKHIKRDLDLLRTMVEKSELWVIKKSSSGGDGKKDKKDKKEPEAVSPEEEADSKKQTTEKSNESYQNVKEILERLNKMCSSGVFKKQ-----QRLLKNMGAHKVMLDLLQISYDR------NDTKMLEIIKYTHLFLQKFCTGNLENQALLHKHLNLFLTPRLLEAE---TMQQIFSNNFQLCSEISESVLHHFIHCLAT-QGRHIQYLNFLHTIIKAE--GKYVKKCQDMIMTELTSAGDDVVVLYTDDTSFNTMVELMTQSREGVKD----DSPLRYHISLVELLAACAEGKNVYTEIKCTSLLPLEEMVKVITHEDCITEVKIAYVNFVNHCYV-----DTEVEMKEIYTSNHIWKLFENF 1433 HSP 2 Score: 151.369 bits (381), Expect = 1.307e-35 Identity = 93/339 (27.43%), Postives = 170/339 (50.15%), Query Frame = -3
Query: 1031 FYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-------------------------------------------NTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFL 1903
Y+ A + S G + +F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F R+ F NTE+ CD+L C ++V+ GL VGD+ P +E F V+Y L F+ ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W+Y++F + +++ DYT + +VA ++K + D+FP +A+ L D D +++ L +S+ + S+ +E + ++R +++ GF+
Sbjct: 2278 LYHVAYVLTSSLGLFVHEFFYSILLFDLIYREETLFNVIKSVTRNGRSILLTAVLAIILVYLFSIVGFLFLRNDFIMEVDHLASPAPGDTESFMSSCSSDGIDCTEETGLLAPAEDEDNTER--ACDTLLMCIITVLNHGLRNGGGVGDVLRK--PSKNEP---LFPARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKLEHNIWNYLYFIVLIREKNKTDYTGPESYVALMIKNKNLDWFPRMQAMSLVVTDGDGEQNEMRNLQDRLSSTMKVVTQLTSQLTELKEQMTEQRKRRQRMGFV 2609
BLAST of SMED30029683 vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]) HSP 1 Score: 220.705 bits (561), Expect = 1.303e-56 Identity = 339/1515 (22.38%), Postives = 618/1515 (40.79%), Query Frame = -3
Query: 4916 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVDEES------------------NVILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFML---VNGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPD-------------EANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCV-------------CNGV------GIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEK--VQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTY--MIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDG---SRDLPFPPERQG-----KELSKEKKKIVQKYQQGDRYLQ------------------SKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRM-MAKSK-WS---------------DEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPF 9013
IGD LY E T+G++ ST ++ + + N P D Q F++ NRY K++ K A + D L ++ AA+ E N +E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D E ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W+IE + G W+ FRF+H T YLA + +S +++ V + D ++F+L P + V SY R+ H+ + W+H+ + K E+E+ + + ++ + +A+ I V P R +F L ++ +L++ + E V ++ F++ NG+ V + RQKL+R ++ + KLL P D A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV CN V I+ + R+ +E G +E + E+ + + +++ ++ + Q G D++ + + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD V+ + P + + +Y N T+ D+ + F D++ +L + + S E N L +V+ L L+ FG+Y + D+ L L+ ++D S P +G K + + + Q +G +L KE +++ K +E+LQ ILN + R++ + FK P+S+ + E P +L + T +L++L + Y + AL +L +S +Q+ A + +L+T+ ++++ + LR + KS+ W + + + I L + C +E QR+L + VV+E+L + EK + +++++ A + L+ Q + +++++ L ++E AIT++ +F+NN LC ++ R + V H + ++L L IVK E +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L Y+ E+ +V + PF
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPESGDLNNPPKKFRDCQ---FRLCPMNRYSAQKQFW-KAAKPGGNSTTDT---VLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKEAILKGGDVVRLFHAEQEKFLTC-----DEHRKKQHVFLRTTGRQSA-TSATSSKAL--WEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAELDSEHEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDK-------EEEKPV---------MLRIGTSAVKEDKEAFAIVPVPPAEVRDLDFANDASKVLASI-AGKLEKGTITQNERRFVTKLLEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLNPANADILIETKLVLSRFEVESGEGPMESEIDE---EEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDV---DLILRCMSDEDLPYDLRASFCRLMLHMHVDRDPQEQVMPVKYARLWSEIPSKIAIDDY-----DNDGTSRDEIKER-----FALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVSTIYPINKMEKGDDNVMKSIHGVGELMTQVVLRGGGFLPTTPTTPPDGDVVKTQTEPEKEDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDETPAPNADGPNSIPNIPVKSHVSTENTPL----------DLDDHGGRT-------FLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSNVEKSELWVYKRQGDEGMDGGDGLPAESDHKKKILLRLSKLC-----VQEGKKQQQRLLRNMGAHSVVLELLQIP-----YEKDVRMQEIMKLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILE---AITMQHIFMNNFQLCSEMNERVVQHFVHCIETHGRHV-QYLKFLQTIVKAE--NKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHKDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRVCNNTSDRKHADTTLESYVTETVMSIVTTFFSSPF 1425 HSP 2 Score: 178.718 bits (452), Expect = 6.605e-44 Identity = 134/560 (23.93%), Postives = 256/560 (45.71%), Query Frame = -3
Query: 1061 KAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNI---SKYNNSLPDFFRNPVPDWKPRF--ENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF--------------NT-----------------------------EKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQK 2575
+A +FY K++ IE+++ D ++++ F + N + +E K V + +R +KI DF S+ + N++ +QKK PI + + W+ L+V++NL++ + G+ + + + + SL P P + +F+ GL + FLL + + + ++ + + R G ++ ++ + Y+ L G + +F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+G+ F+ F NT +K CDSL C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+FF + ++ + ++T + +VA ++++ D+FP RA+ L + D + ++I L + + + + + S+ +E +R+K
Sbjct: 2048 EALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFYPLEGGGTLEPHLSALLWAAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTL---FLLGAFNVGN-----KVIFLMSFVGNR----------------GTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIIFKDDFILTVDRISNKTLGENTSKMGEFLAGAVCRKEENSVGVQSSALVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQVREK 2578
BLAST of SMED30029683 vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]) HSP 1 Score: 217.624 bits (553), Expect = 1.177e-55 Identity = 346/1545 (22.39%), Postives = 629/1545 (40.71%), Query Frame = -3
Query: 4916 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVDEES------------------NVILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFML---VNGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPD-------------EANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCV-------------CNGV------GIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEK--VQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTY--MIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDG---SRDLPFPPERQG---------KELSKEKKKIVQKYQQGDRYLQ------------------SKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFK-ECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLR------------------------MMAKSKWSDEQ---VNRMEN------IFSELIEFCHLPKAP--EEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPF 9013
IGD LY E T+G++ ST ++ + + N P D Q F++ NRY K++ K A + D L ++ AA+ E N +E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D E ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W+IE + G W+ FRF+H T YLA + +S +++ V + D ++F+L P + V SY R+ H+ + W+H+ + K E+E+ + + ++ + +A+ I V P R +F L ++ +L++ + E V ++ F++ NG+ V + RQKL+R ++ + KLL P D A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV CN V I+ + R+ +E G +E + E+ + + +++ ++ + Q G D++ + + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD V+ + P + + +Y N T+ D+ + F D++ +L + + S E N L +V+ L L+ FG+Y + D+ L L+ ++D S P +G K + + + Q +G +L KE +++ K +E+LQ ILN + R++ + FK E + N P+S+ F E++ + E T + +D +L++L + Y + AL +L +S +Q+ A + +L+T+ ++++ + LR + A+ SD++ N +N I L + C + + P ++ QR+L + VV+E+L + + + + K+ + LQ A + QNQ + +++++ L ++E AIT++ +F+NN LC ++ R + V H + ++L L IVK E +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L Y+ E+ +V + PF
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPESGDLNNPPKKFRDCQ---FRLCPMNRYSAQKQFW-KAAKPGGNSTTDT---VLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKEAILKGGDVVRLFHAEQEKFLTC-----DEHRKKQHVFLRTTGRQSA-TSATSSKAL--WEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAELDSEHEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDK-------EEEKPV---------MLRIGTSAVKEDKEAFAIVPVPPAEVRDLDFANDASKVLASI-AGKLEKGTITQNERRFVTKLLEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLNPANADILIETKLVLSRFEVESGEGPMESEIDE---EEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDV---DLILRCMSDEDLPYDLRASFCRLMLHMHVDRDPQEQVMPVKYARLWSEIPSKIAIDDY-----DNDGTSRDEIKER-----FALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVSTIYPINKMEKGDESKSSNVMKSIHGVGELMTQVVLRGGGFLPTTPTTPPDGDVVKTQTEPEKEDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDEN-------GPNSIPNIPALDFENIEEQAEGIFGGS----------EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSNVEKSELWVYKRQGDEGMDGGDGLPAEDSGSDKKKTDGNGSDNYRDVKEILLRLSKLC-VQEGPSGKKSKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVRMQEIMKLAHEFLQNFCAG-----NQQNQALLHKHINLFLNPGILE---AITMQHIFMNNFQLCSEMNERVVQHFVHCIETHGRHV-QYLKFLQTIVKAE--NKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHKDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRVCNNTSDRKHADTTLESYVTETVMSIVTTFFSSPF 1459 HSP 2 Score: 184.496 bits (467), Expect = 1.471e-45 Identity = 136/569 (23.90%), Postives = 262/569 (46.05%), Query Frame = -3
Query: 1025 KAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNI---SKYNNSLPDFFRNPVPDWKPRF--ENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF--------------NT--------------------------EKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 2575
+A +FY K++ IE+++ D ++++ F + N + +E K V + +R +KI DF S+ + N++ +QKK PI + + W+ L+V++NL++ + G+ + + + + SL P P + +F+ GL + FLL + + + ++ + + R G ++ ++ + Y+ L G + +F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+G+ F+ F N+ +K CDSL C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+FF + ++ + ++T + +VA ++++ D+FP RA+ L + D + ++I L + + + + + S+ +E + ++R QK+ G L +
Sbjct: 2087 EALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFYPLEGGGTLEPHLSALLWAAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTL---FLLGAFNVGN-----KVIFLMSFVGNR----------------GTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIIFKDDFILTVDRISNKTLGENSRCMGEFLAGAVCRKEENFQSSALVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQMTEQRKQKQRIGLLGH 2626
BLAST of SMED30029683 vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3]) HSP 1 Score: 217.238 bits (552), Expect = 1.710e-55 Identity = 352/1554 (22.65%), Postives = 627/1554 (40.35%), Query Frame = -3
Query: 4916 IGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQP--SHIPDP----QMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVDEES------------------NVILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFM------------LVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPD-------------EANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCV-------------CNGVGIVDNQTYIAQRWLLEDR---RGVYLTERGQNIHEQPNILYV----STDCMKSWIALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE---NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSR-DLPF--PPERQGKELSKEKKKI-------VQKYQQGDRYLQS------------------KETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFK-----ECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDEQVNRME------------------------------NIFSELIEFCHLPK-APEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYILEQPMETREAVLKEELGEDH-VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFI-----------GNLGEEIH---YLTQYILESPHELVYYLLTKPF 9013
IGD LY E STS F + L + + QP + +P + F++ NRY K++ K A + D L ++ AA+ E N +E ++ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D E ++GG V+LFH E E ++ D ++ ++ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA + +S ++ V + D ++F+L P + V SY R+ H+ + W+H+ Q E++ M I G K D +A+ I V P R +F L ++ +L++ + E V ++ F+ + K + RQKL+R ++ + KLL P D A F + CY +L Y RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV CN V N + + L+ R G L E + E +++ S +KS ++ + Q G+ D E + + QL+LF +C R I I+ L + + E LP D+RA +C M++ + VD V + P + + +Y N T+SD+ + F +++ +L + ++ + K E N L +V+ L L+ FG+Y + D+ L L+ ++D PF +R+ + S + I Q +G +L + K+ +++ K +E+LQ ILN + R++ + FK ++E L ++P+S+ AL F E++ + E T + +D +L++L + Y + AL +L +S +Q+ QA + +L+T+ ++++ + LR + K + SD ++ E I L + C L + ++ QR+L + VV+E+L + EK + L + QNQ + +++++ L ++E A+T++ +F+NN LC +I R + V H ++ +L L IVK E +K+ Q +VM ++ + Y+ A Q + + +E L E ++Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N + H L +Y+ E+ +V + PF
Sbjct: 11 IGDVCSLYAEG--------STSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFW-KAAKPGGTSTTDT---VLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGDVVRLFHAEQEKFLTC-----DEHRKKQYVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHS------TNQPIDKEEEKPVMLRI---GTSPLKED-------KEAFAIVPVSPAEVRDLDFANDASKVLASIAA-KLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHICRLCYRVL-RYSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSK-SIRELAQDAKDGHTEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQLDV---DLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDY-----DNDGTSSDEVKER-----FSQTMEFVENYLRDVVCQSFPFSDK-EKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHISTPFHIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEVKAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKTEFDESNSQSEPSLSPESPASVQGAL--DFEHIEEQAEGIFGGS----------EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYKRQGSDSGLDAGEVTPEAHHKVRIRSNKPKVESTSSSNYRVVKEILLRLSKLCVLEGISGKKNKKQQQRLLRNMGAHSVVLELLQIP-----YEKGEDVQMQEIMTLAHQFLQNFCAGNQQNQALLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINERVVQHFVHCIETH-GRSVHYLKFLQTIVKAE--NKFIKKCQDIVMAELVTAGEDVLVFYNDRASF--QSLVQMMRLERERLDESSALRYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYV-----DTEVEMKEIYTSNHMWKLFDDFLVDVCRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPF 1474 HSP 2 Score: 192.586 bits (488), Expect = 4.977e-48 Identity = 145/600 (24.17%), Postives = 270/600 (45.00%), Query Frame = -3
Query: 1013 LIITPN-QQKAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYN-------NSLPDFFRNPVPDWKPRF--ENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKN-------------------------------------LYC-----------------DSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSL 2599
+++ P + +A ++Y K++ IE+++ D ++++ F + N + + E K V + +R +KI DF + + N++R+QKK P+ + + W+ L+V++NL L F P DG + S SL +P P+ + F+ GL H + LL + + + +I + + R G R ++ + ++ L + G + +F++ L ++V+ + L VI +VT+NG+S++ A+LG++++YL++I+G+ FF+ F E N ++C DSLW C ++V+ GL VGD+ P E+ F+ V+Y L FF L+ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W Y+FF + ++ + +YT + +VA ++KE D+FP RA+ L + D + +++ L + + + + + ++ +E + ++R K+ G L N L
Sbjct: 2154 ILLKPGGEDQALEYYTKHTSQIEIVRQDRTMEQIVFPVPNICSFLTNESKLRVYYGTERDEQGSKINDFFLHADDLFNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINL--LVAFFYPLDGVSESQLEPSLSLLLWVCLLGSLGFVLMSPRPNAVRVLVISTVLQLGFSVGLQHMLT---LLGAFNVCN-----KIVFMLSFVGNR----------------GSFTRGYRVMVMDREFLFHLLYLLICILGLFGHVFFYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGTLAKAQTSDLLAVRRLFTIIINSCILILKCHKIHCLNPTDCVCFIDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRK--PSKEER---LFAARVVYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRLGLLGNPAHL 2722
BLAST of SMED30029683 vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]) HSP 1 Score: 216.468 bits (550), Expect = 2.369e-55 Identity = 341/1531 (22.27%), Postives = 619/1531 (40.43%), Query Frame = -3
Query: 4916 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN-------------------------VILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFML---VNGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPD-------------EANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCV-------------CNGV------GIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEK--VQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTY--MIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDG---SRDLPFPPERQG-----KELSKEKKKIVQKYQQGDRYLQ------------------SKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRM-MAKSK-W-------------------SDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPF 9013
IGD LY E T+G++ ST ++ + + N P D Q F++ NRY K++ K A + D L ++ AA+ E N +E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D E ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W+IE + G W+ FRF+H T YLA + + ++ V + D ++F+L P + V SY R+ H+ + W+H+ + K E+E+ + + ++ + +A+ I V P R +F L ++ +L++ + E V ++ F++ NG+ V + RQKL+R ++ + KLL P D A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV CN V I+ + R+ +E G +E + E+ + + +++ ++ + Q G D++ + + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD V+ + P + + +Y N T+ D+ + F D++ +L + + S E N L +V+ L L+ FG+Y + D+ L L+ ++D S P +G K + + + Q +G +L KE +++ K +E+LQ ILN + R++ + FK P+ A +G N P ++ T + +D +L++L + Y + AL +L +S +Q+ A + +L+T+ ++++ + LR + KS+ W SD + + I L + C +E QR+L + VV+E+L + EK + +++++ A + L+ Q + +++++ L ++E AIT++ +F+NN LC ++ R + V H + ++L L IVK E +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L Y+ E+ +V + PF
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPESGDLNNPPKKFRDCQ---FRLCPMNRYSAQKQFW-KAAKPGGNSTTDT---VLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKEAILKGGDVVRLFHAEQEKFLTC-----DEHRKKQHVFLRTTGRQSA-TSATSSKAL--WEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEESQESRSSVTRLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDK-------EEEKPV---------MLRIGTSAVKEDKEAFAIVPVPPAEVRDLDFANDASKVLASI-AGKLEKGTITQNERRFVTKLLEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLNPANADILIETKLVLSRFEVESGEGPMESEIDE---EEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDV---DLILRCMSDEDLPYDLRASFCRLMLHMHVDRDPQEQVMPVKYARLWSEIPSKIAIDDY-----DNDGTSRDEIKER-----FALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVSTIYPINKMEKGDDNVMKSIHGVGELMTQVVLRGGGFLPTTPTTPPDGDVVKTQTEPEKEDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNTQTDTAPAPNA----DGPNSIPNIP------------VKSHVSTNTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSNVEKSELWVYKRQGDEGMDGGDGLPAESDHKKKVL--ILLRLSKLC-----VQEGKKQQQRLLRNMGAHSVVLELLQIP-----YEKDVRMQEIMKLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILE---AITMQHIFMNNFQLCSEMNERVVQHFVHCIETHGRHV-QYLKFLQTIVKAE--NKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHKDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRVCNNTSDRKHADTTLESYVTETVMSIVTTFFSSPF 1440 HSP 2 Score: 182.956 bits (463), Expect = 4.088e-45 Identity = 134/551 (24.32%), Postives = 256/551 (46.46%), Query Frame = -3
Query: 1061 KAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNI---SKYNNSLPDFFRNPVPDWKPRF--ENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF--------------NT--------------------EKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQK 2575
+A +FY K++ IE+++ D ++++ F + N + +E K V + +R +KI DF S+ + N++ +QKK PI + + W+ L+V++NL++ + G+ + + + + SL P P + +F+ GL + FLL + + + ++ + + R G ++ ++ + Y+ L G + +F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+G+ F+ F NT +K CDSL C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+FF + ++ + ++T + +VA ++++ D+FP RA+ L + D + ++I L + + + + + S+ +E +R+K
Sbjct: 2052 EALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFYPLEGGGTLEPHLSALLWAAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTL---FLLGAFNVGN-----KVIFLMSFVGNR----------------GTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIIFKDDFILTVDRISNKTLGENTTTGNKKNCNCVTSSSALVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQVREK 2573
BLAST of SMED30029683 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811]) HSP 1 Score: 241.891 bits (616), Expect = 7.827e-63 Identity = 341/1490 (22.89%), Postives = 624/1490 (41.88%), Query Frame = -3
Query: 4997 IGDFICLYCEETD-GYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLR-KFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVD-EESNVIL-------------VKESRDPRTVFKLHPV-IQDSEE-VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLV----NGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVH--------------LECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNI-----------HEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSV---------VDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYY-------------GDVDDV---RSLLDKLIGLIDGS---------------RDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELRE-MFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSDEQVNR---------------------MENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNL 9013
IGD + LY E T G++ ST ++ + N P D F++ NRY K+Y + K A + E + D L + + AA E N E ++ + V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P +K++S G+ V + D++ L + + G HAS + L + E+N + + I + D E ++GG V+LFH E E ++ D ++H+ +R + +A + +SN+ W++E G W+ +RF+H T YLA + E ++++ V D ++F+L P +Q ++ V S+ R+ H+ + W+ Q + D IR G + +A+ I V R +F L N +E RL E F+ ++ R + E F +V NG++V + RQKL+R ++ + +L P + + L++ CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + G+ + E ++ Y + +W ++ + Q G +D+ + + QL LF +C R I I+K LS + FL + E+LP ++RA +C +++ + VD V + P + +Y D N + D K + + D++ + E+ M S + N L +V+ L L+ FG+Y G +D V +S+L + I DG+ + ++ G S+ +V R E ++ K LE+LQ ILN + R++ ++ FK+ E E + N + ++ N +++ + I EL E MF +T+ +++D +LI L Y + +L++L +S +Q+ + +L++T ++ + ++ LR M + W D++ N ++ I L + C+ PE+ QR+L + + V++++L V + + T + +++L+ Q L+ P+ Q + ++L + L L E+E T++ +F+NN LC +I + + A H + ++LD L I+K E G +K+ Q ++M + + +S A +LE REA+ EE ++Y ISL++LL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW N
Sbjct: 10 IGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFRVCPMNRYSAQKQYWKAKQAKQDKEKISDV---LLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNA-GQPLHAS-NYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTC-----DEYKSRLHVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLVMQGPEKMIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWI----------QSTNVPIDVDEERPIRLMLG------TCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLANFVE-RLNEGFI-SQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGVMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTEGEGVLSILEGGGKMSPEYMSLEYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSV---DLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDY----DSNLNDSRDNKKNK-FTSTMEFVEDYLNNVVSES--MPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDNAADGTAPAFDSTN------ASLNLDR--IGELAEAMFGSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKSELDRLRTMVEKSELWVDKKGNTGIIGSTDGKPVMEKSSENYQIVKGILETLNKMCN---GPEQVRKKQQRLLKNMDAHKVMLDLLQVPYEKEDT----KMKEILKYTHQFLQKFCATNPENQALLHKHLSLFLTPGLQEAE---TMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHV-QYLDFLHTIIKAE--GKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMMATAREAI--EE--NSPLKYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENF 1416 HSP 2 Score: 144.05 bits (362), Expect = 3.763e-33 Identity = 132/518 (25.48%), Postives = 239/518 (46.14%), Query Frame = -3
Query: 1052 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-------------------------NTEKNLY----------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEELLRQKRWQ 2476
+ EE K V ++ +K+ DF D S + N++ +Q+K + P+ +F+ LW L+V +NL+ + F +G D + F V F + + +G ++ L Y+L P+ +IL L N++ + +G ++ ++ + Y+ A + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + F T+K L CD+L C ++V+ GL VGD+ P E F ++Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I L L + L++H + SE K E R ++WQ
Sbjct: 2084 LTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGTISFNLAVFINLI-IAFFYPYVEGILDSPL--------ISLLFWGMVC-----FSVMSLFTKRYGFRPLIVALILRSVYYLGIGPT------LYILGALNLT-NKIVFVVSFVGNRGTFIRGYKAMVMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFIMEVDRLPKGKRDLFPAVRLGSLTPPTKKKLLLWEEGDVERACDTLLMCIITVLNHGLRNGGGVGDILRK--PSKDET---LFPARIVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELK---EQQRSQQWQ 2572
BLAST of SMED30029683 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811]) HSP 1 Score: 237.654 bits (605), Expect = 1.231e-61 Identity = 356/1560 (22.82%), Postives = 645/1560 (41.35%), Query Frame = -3
Query: 4880 IGDFICLYCEETD-GYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLR-KFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLA--VDEESNVILVKESR---------------------DPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLV----NGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVH--------------LECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWL----------LEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSV---------VDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYY-------------GDVDDV---RSLLDKLIGLIDGS---------------RDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELRE-MFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSDEQVNR--------------------------------MENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI---------HYLTQYILESPHELVYYLLTKPFPKH---LKTHLTCSI 9013
IGD + LY E T G++ ST ++ + N P D F++ NRY K+Y + K A + E + D L + + AA E N E ++ + V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P +K++S G+ V + D++ L + + G HAS + L + E+N + + I + D E ++GG V+LFH E E ++ D ++H+ +R + +A + +SN+ W++E G W+ +RF+H T YLA V E S V+ V +S D ++F+L P +Q ++ V S+ R+ H+ + W+ Q + D IR G + +A+ I V R +F L N +E RL E F+ ++ R + E F +V NG++V + RQKL+R ++ + +L P + + L++ CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L E + + E G + + ++ Y + +W ++ + Q G +D+ + + QL LF +C R I I+K LS + FL + E+LP ++RA +C +++ + VD V + P + +Y D N + D K + + D++ + E+ M S + N L +V+ L L+ FG+Y G +D V +S+L + I DG+ + ++ G S+ +V R E ++ K LE+LQ ILN + R++ ++ FK+ E E + N + ++ N +++ + I EL E MF +T+ +++D +LI L Y + +L++L +S +Q+ + +L++T ++ + ++ LR M + W D++ N ++ I L + C+ PE+ QR+L + + V++++L V + + T + +++L+ Q L+ P+ Q + ++L + L L E+E T++ +F+NN LC +I + + A H + ++LD L I+K E G +K+ Q ++M + + +S A +LE REA+ EE ++Y ISL++LL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L E + PF ++ L+TH T +
Sbjct: 10 IGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFRVCPMNRYSAQKQYWKAKQAKQDKEKISDV---LLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNA-GQPLHAS-NYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTC-----DEYKSRLHVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLVMQVDKSHYFRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWI----------QSTNVPIDVDEERPIRLMLG------TCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLANFVE-RLNEGFI-SQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGVMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTEGEGVLSILEGGGSRRGERDLEYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSV---DLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDY----DSNLNDSRDNKKNK-FTSTMEFVEDYLNNVVSES--MPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDNAADGTAPAFDSTN------ASLNLDR--IGELAEAMFGSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKSELDRLRTMVEKSELWVDKKGNTGIIGSTDGNKKDKKEDNSGKPVMEKSSENYQIVKGILETLNKMCN---GPEQVRKKQQRLLKNMDAHKVMLDLLQVPYEKEDT----KMKEILKYTHQFLQKFCATNPENQALLHKHLSLFLTPGLQEAE---TMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHV-QYLDFLHTIIKAE--GKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMMATAREAI--EE--NSPLKYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFILDMARVKKRIVDSTLEKYVLTVVLETIRSFFNSPFSENSTSLQTHQTIVV 1486 HSP 2 Score: 140.584 bits (353), Expect = 3.960e-32 Identity = 132/532 (24.81%), Postives = 247/532 (46.43%), Query Frame = -3
Query: 1088 SVSIELLKGDY-LQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-------------------------NTEKNLY----------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERK 2548
+ IE+++ D ++++ F + + + EE K V ++ +K+ DF D S + N++ +Q+K + P+ +F+ LW L+V +NL++ F P + E +I K R + + +G ++ L Y+L P+ +IL L N++ + +G ++ ++ + Y+ A + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + F T+K L CD+L C ++V+ GL VGD+ P E F ++Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I L L + L++H + SE K
Sbjct: 2081 TAQIEIVRMDRSMEQIVFSVPSICKFLTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGTISFNLAVFINLII--AFFYP----YVEGTSIGK------------------RLFIMSLFTKRYGFRPLIVALILRSVYYLGIGPT------LYILGALNLT-NKIVFVVSFVGNRGTFIRGYKAMVMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFIMEVDRLPKGKRDLFPAVRLGSLTPPTKKKLLLWEEGDVERACDTLLMCIITVLNHGLRNGGGVGDILRK--PSKDET---LFPARIVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELK 2576
BLAST of SMED30029683 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811]) HSP 1 Score: 236.498 bits (602), Expect = 3.250e-61 Identity = 354/1562 (22.66%), Postives = 644/1562 (41.23%), Query Frame = -3
Query: 4880 IGDFICLYCEETD-GYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLR-KFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLA--VDEESNVILVKESR---------------------DPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLV----NGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVH--------------LECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNI----------HEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSV---------VDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYY-------------GDVDDV---RSLLDKLIGLIDGS---------------RDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELRE-MFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSDEQVNR----------------------------------MENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI---------HYLTQYILESPHELVYYLLTKPFPKH---LKTHLTCSI 9013
IGD + LY E T G++ ST ++ + N P D F++ NRY K+Y + K A + E + D L + + AA E N E ++ + V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P +K++S G+ V + D++ L + + G HAS + L + E+N + + I + D E ++GG V+LFH E E ++ D ++H+ +R + +A + +SN+ W++E G W+ +RF+H T YLA V E S V+ V +S D ++F+L P +Q ++ V S+ R+ H+ + W+ Q + D IR G + +A+ I V R +F L N +E RL E F+ ++ R + E F +V NG++V + RQKL+R ++ + +L P + + L++ CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + G+ + + ++ Y + +W ++ + Q G +D+ + + QL LF +C R I I+K LS + FL + E+LP ++RA +C +++ + VD V + P + +Y D N + D K + + D++ + E+ M S + N L +V+ L L+ FG+Y G +D V +S+L + I DG+ + ++ G S+ +V R E ++ K LE+LQ ILN + R++ ++ FK+ E E + N + ++ N +++ + I EL E MF +T+ +++D +LI L Y + +L++L +S +Q+ + +L++T ++ + ++ LR M + W D++ N ++ I L + C+ PE+ QR+L + + V++++L V + + T + +++L+ Q L+ P+ Q + ++L + L L E+E T++ +F+NN LC +I + + A H + ++LD L I+K E G +K+ Q ++M + + +S A +LE REA+ EE ++Y ISL++LL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L E + PF ++ L+TH T +
Sbjct: 10 IGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFRVCPMNRYSAQKQYWKAKQAKQDKEKISDV---LLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNA-GQPLHAS-NYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTC-----DEYKSRLHVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLVMQVDKSHYFRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWI----------QSTNVPIDVDEERPIRLMLG------TCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLANFVE-RLNEGFI-SQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGVMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTEGEGVLSILEGGGSRRGERDLEYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSV---DLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDY----DSNLNDSRDNKKNK-FTSTMEFVEDYLNNVVSES--MPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDNAADGTAPAFDSTN------ASLNLDR--IGELAEAMFGSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKSELDRLRTMVEKSELWVDKKGNTGIIGSTDGNKKDKKENQDNSGKPVMEKSSENYQIVKGILETLNKMCN---GPEQVRKKQQRLLKNMDAHKVMLDLLQVPYEKEDT----KMKEILKYTHQFLQKFCATNPENQALLHKHLSLFLTPGLQEAE---TMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHV-QYLDFLHTIIKAE--GKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMMATAREAI--EE--NSPLKYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFILDMARVKKRIVDSTLEKYVLTVVLETIRSFFNSPFSENSTSLQTHQTIVV 1488 HSP 2 Score: 132.88 bits (333), Expect = 9.180e-30 Identity = 131/548 (23.91%), Postives = 247/548 (45.07%), Query Frame = -3
Query: 1088 SVSIELLKGDY-LQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSG------------------------------------FNTEKNLY---------------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERK 2548
+ IE+++ D ++++ F + + + EE K V ++ +K+ DF D S + N++ +Q+K + P+ +F+ LW L+V +NL++ F P + E +I K R + + +G ++ L Y+L P+ +IL L N++ + +G ++ ++ + Y+ A + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + FN+ + Y CD+L C ++V+ GL VGD+ P E F ++Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I L L + L++H + SE K
Sbjct: 2106 TAQIEIVRMDRSMEQIVFSVPSICKFLTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGTISFNLAVFINLII--AFFYP----YVEGTSIGK------------------RLFIMSLFTKRYGFRPLIVALILRSVYYLGIGPT------LYILGALNLT-NKIVFVVSFVGNRGTFIRGYKAMVMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFIMEVDRLPKGNFIAPCMDCMDFLLDRRLHWLVFFFFNSPYSSYTYIVLLDEEGDVERACDTLLMCIITVLNHGLRNGGGVGDILRK--PSKDET---LFPARIVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELK 2617
BLAST of SMED30029683 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811]) HSP 1 Score: 234.958 bits (598), Expect = 9.668e-61 Identity = 352/1554 (22.65%), Postives = 640/1554 (41.18%), Query Frame = -3
Query: 4889 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLR-KFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVD-EESNVILVKESR------------------DPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLV----NGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVH--------------LECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQP---NILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSV---------VDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYY-------------GDVDDV---RSLLDKLIGLIDGS---------------RDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSDEQVNR-------------------------------------MENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI-------------HYLTQYILESPHELVYYLLTKPFPKH---LKTHLT 9013
IGD + LY E T G++ ST ++ + N P D F++ NRY K+Y + K A + E + D L + + AA E N E ++ + V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P +K++S G+ V + D++ L + + G HAS + L + E+N + + I + D E ++GG V+LFH E E ++ D ++H+ +R + +A + +SN+ W++E G W+ +RF+H T YLA + E ++++ + SR D ++F+L P +Q ++ V S+ R+ H+ + W+ Q + D IR G + +A+ I V R +F L N +E RL E F+ ++ R + E F +V NG++V + RQKL+R ++ + +L P + + L++ CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + +L+ + L + I P N+ Y + +W ++ + Q G +D+ + + QL LF +C R I I+K LS + FL + E+LP ++RA +C +++ + VD V + P + +Y D N + D K + + D++ + E+ M S + N L +V+ L L+ FG+Y G +D V +S+L + I DG+ + ++ G S+ +V R E ++ K LE+LQ ILN + R++ ++ FK+ E E + N + +G P + P L+ + L T+ +++D +LI L Y + +L++L +S +Q+ + +L++T ++ + ++ LR M + W D++ N ++ I L + C+ PE+ QR+L + + V++++L V + + T + +++L+ Q L+ P+ Q + ++L + L L E+E T++ +F+NN LC +I + + A H + ++LD L I+K E G +K+ Q ++M + + +S A +LE REA+ EE ++Y ISL++LL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L E + PF ++ L+TH T
Sbjct: 10 IGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFRVCPMNRYSAQKQYWKAKQAKQDKEKISDV---LLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNA-GQPLHAS-NYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTC-----DEYKSRLHVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLVITRPSRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWI----------QSTNVPIDVDEERPIRLMLG------TCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLANFVE-RLNEGFI-SQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGVMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELIC-KCVLDPKNSDILIKTDLQITCPPRMSNLQYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSV---DLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDY----DSNLNDSRDNKKNK-FTSTMEFVEDYLNNVVSES--MPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDNAA-------DG-TPLLRSP-------LVPQPLGNEQRGTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKSELDRLRTMVEKSELWVDKKGNTGIIGSTDGNKKDKKEHVENQDNSGKPVMEKSSENYQIVKGILETLNKMCN---GPEQVRKKQQRLLKNMDAHKVMLDLLQVPYEKEDT----KMKEILKYTHQFLQKFCATNPENQALLHKHLSLFLTPGLQEAE---TMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHV-QYLDFLHTIIKAE--GKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMMATAREAI--EE--NSPLKYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFILDMARVCNKREKRIVDSTLEKYVLTVVLETIRSFFNSPFSENSTSLQTHQT 1472 HSP 2 Score: 140.198 bits (352), Expect = 4.803e-32 Identity = 131/535 (24.49%), Postives = 247/535 (46.17%), Query Frame = -3
Query: 1073 SVSIELLKGDY-LQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLY---------------------------------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERKRFEEL 2548
+ IE+++ D ++++ F + + + EE K V ++ +K+ DF D S + N++ +Q+K + P+ +F+ LW L+V +NL+ + F +G D + F V F + + +G ++ L Y+L P+ +IL L N++ + +G ++ ++ + Y+ A + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + F E + CD+L C ++V+ GL VGD+ P E F ++Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I L L + L++H + SE K +L
Sbjct: 2071 TAQIEIVRMDRSMEQIVFSVPSICKFLTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGTISFNLAVFINLI-IAFFYPYVEGILDSPL--------ISLLFWGMVC-----FSVMSLFTKRYGFRPLIVALILRSVYYLGIGPT------LYILGALNLT-NKIVFVVSFVGNRGTFIRGYKAMVMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFIMEVDRLPKGNPMAPNNFAEFCEKDQTDCTVDEEGDVERACDTLLMCIITVLNHGLRNGGGVGDILRK--PSKDET---LFPARIVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELKEQNDL 2579
BLAST of SMED30029683 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811]) HSP 1 Score: 234.572 bits (597), Expect = 1.374e-60 Identity = 356/1552 (22.94%), Postives = 640/1552 (41.24%), Query Frame = -3
Query: 4880 IGDFICLYCEETD-GYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLR-KFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLA--VDEESNVILVKESR---------------------DPRTVFKLHPV-IQDSEE-VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLV----NGKSV---------KARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVH--------------LECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQP----NILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSV---------VDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYY-------------GDVDDV---RSLLDKLIGLIDGS---------------RDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKE--------CERNEGLLKKKNPSSL--ACALYEGFNPYEKKPSAVRKQKLMIK---ELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSDEQVNR-----------------------MENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI---------HYLTQYILESPHELVYYLLTKPFPKH---LKTHLTCSI 9013
IGD + LY E T G++ ST ++ + N P D F++ NRY K+Y + K A + E + D L + + AA E N E ++ + V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P +K++S G+ V + D++ L + + G HAS + L + E+N + + I + D E ++GG V+LFH E E ++ D ++H+ +R + +A + +SN+ W++E G W+ +RF+H T YLA V E S V+ V +S D ++F+L P +Q ++ V S+ R+ H+ + W+ Q + D IR G + +A+ I V R +F L N +E RL E F+ ++ R + E F +V NG++V + RQKL+R ++ + +L P + + L++ CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + + + E ++ Y + +W ++ + Q G +D+ + + QL LF +C R I I+K LS + FL + E+LP ++RA +C +++ + VD V + P + +Y D N + D K + + D++ + E+ M S + N L +V+ L L+ FG+Y G +D V +S+L + I DG+ + ++ G S+ +V R E ++ K LE+LQ ILN + R++ ++ FK+ + N+G KK P +L A +L+ + RK M++ E MF +LI L Y + +L++L +S +Q+ + +L++T ++ + ++ LR M + W D++ N ++ I L + C+ PE+ QR+L + + V++++L V + + T + +++L+ Q L+ P+ Q + ++L + L L E+E T++ +F+NN LC +I + + A H + ++LD L I+K E G +K+ Q ++M + + +S A +LE REA+ EE ++Y ISL++LL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L E + PF ++ L+TH T +
Sbjct: 10 IGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFRVCPMNRYSAQKQYWKAKQAKQDKEKISDV---LLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNA-GQPLHAS-NYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTC-----DEYKSRLHVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLVMQVDKSHYFRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWI----------QSTNVPIDVDEERPIRLMLG------TCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLANFVE-RLNEGFI-SQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGVMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTELRPLKEMSPEYMSLEYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSV---DLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDY----DSNLNDSRDNKKNK-FTSTMEFVEDYLNNVVSES--MPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVGETLKSNKG-GSKKGPLTLPAATSLFRSIFVF-----LCRKSTSMLEVDDEGGRMF-----------LRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKSELDRLRTMVEKSELWVDKKGNTGIIGSTDGNKKDKKEKSSENYQIVKGILETLNKMCN---GPEQVRKKQQRLLKNMDAHKVMLDLLQVPYEKEDT----KMKEILKYTHQFLQKFCATNPENQALLHKHLSLFLTPGLQEAE---TMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHV-QYLDFLHTIIKAE--GKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMMATAREAI--EE--NSPLKYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFILDMARVKKRIVDSTLEKYVLTVVLETIRSFFNSPFSENSTSLQTHQTIVV 1470 HSP 2 Score: 132.494 bits (332), Expect = 1.140e-29 Identity = 131/549 (23.86%), Postives = 248/549 (45.17%), Query Frame = -3
Query: 1088 NSVSIELLKGDY-LQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSG------------------------------------FNTEKNLY---------------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDEL---LKNVSTLINHQKSEDSERK 2551
++ IE+++ D ++++ F + + + EE K V ++ +K+ DF D S + N++ +Q+K + P+ +F+ LW L+V +NL++ F P + E +I K R + + +G ++ L Y+L P+ +IL L N++ + +G ++ ++ + Y+ A + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + FN+ + Y CD+L C ++V+ GL VGD+ P E F ++Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I L L + L++H + SE K
Sbjct: 2087 HTAQIEIVRMDRSMEQIVFSVPSICKFLTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGTISFNLAVFINLII--AFFYP----YVEGTSIGK------------------RLFIMSLFTKRYGFRPLIVALILRSVYYLGIGPT------LYILGALNLT-NKIVFVVSFVGNRGTFIRGYKAMVMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFIMEVDRLPKGNFIAPCMDCMDFLLDRRLHWLVFFFFNSPYSSYTYIVLLDEEGDVERACDTLLMCIITVLNHGLRNGGGVGDILRK--PSKDET---LFPARIVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELK 2599
BLAST of SMED30029683 vs. Ensembl Mouse
Match: Itpr3 (inositol 1,4,5-triphosphate receptor 3 [Source:MGI Symbol;Acc:MGI:96624]) HSP 1 Score: 227.639 bits (579), Expect = 1.253e-58 Identity = 345/1573 (21.93%), Postives = 651/1573 (41.39%), Query Frame = -3
Query: 4880 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIED-ENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN-------------------------------VILVKESRDPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALK---DKEYKR------QQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLE----------------CYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL-------TERGQNIHEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKD-----LVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID---------------GSRDLPFPPERQGKELS----KEKKKI---------VQKYQQGDRY-LQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSD-------------------------------------EQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDH--VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHY-------------LTQYILESPHELVYYLLTKPFPKH---LKTHLTCSI 9013
IGD + LY E + +G++ ST ++ + N P D F++ NRY K+Y + +D E + D L + + AA+ E N E ++ V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + I P +K++S G+ V + D++IL + + G HAS + L + E+N + + I D E ++GG V+LFH E E ++ D ++ + +R + +A + +SN+ W++E G W+ +RF+H T YLA +E + ++ V D ++F+L P +Q ++ V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A ++K+ + + F+ LLED + F + V + + + M+ K + RQKL+R ++ + +L P + E V LE CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + E Q+ HE +I Y + +W ++ + Q G +D+ + + QL LF +C R I I+K L E FL + E+LP D+RA +C +++ + VD + +V + + ++ + T K S+ A++D + + D++ + E + E N+L +V+ L + L+ FG+Y ++ L L+G+ID G +++ + G +S K+ + V +Q DR + E + ++ K LE+LQ ILN + R++ ++ FK+ E E + + + +G P +A + ++ MF + ++ +++D +L++L + Y + AL++L +S +Q+ + +L++ ++ + ++ LR M + W D E ++ I L + C + E+ QR+L + + V++++L + ++D+++ E T + L+K P Q + ++L + L L+E+E T++ +F+NN LC +I + V L A H + ++LD L ++K E G +K+ Q ++M + + +S A++L+ R+ V EDH + Y ISL++LL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L + + + PF ++ L+TH T +
Sbjct: 10 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADV---VLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHAS-NYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTC-----DEYRGKLQVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQND-----RRFVIQLLEDLV---FFVSD----VPNNGQNVLDIMVT--KPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPL--VRLEELSDQKNAPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGMMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQS-HEYLSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISKQLGV---ELLFLCMADEMLPFDLRASFCHLMLHVHVD-RDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFASTMEFVEDYLNNVVSEAVPF--ANDEKNILTFEVVSLAHNLIYFGFYS-FSELLRLTRTLLGIIDCIQAPAAMLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPAGVGVPEQLDRSKFEDNEHTVVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDSGA-------DGTAPAFDSSTATMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLLHLTMHDYPSLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSVKGEEVEAGATKDKKERPSDEEGFLQPHGEKSSENYQIVKGILERLNKMCGV---GEQMRKKQQRLLKNMDAHKVMLDLLQIPYDKSDNKMLEILRYTHQFLQKFCAGN-------PGNQALLHKHLQLFLTPGLLEAE---TMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHV-QYLDFLHTVIKAE--GKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGV------EDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVTVVTHEDCITEVKMAYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFTLDMALVCNKREKRLSDPTLEKYVLTVVLDTISAFFSSPFSENSTSLQTHQTIVV 1499 HSP 2 Score: 151.754 bits (382), Expect = 1.208e-35 Identity = 192/876 (21.92%), Postives = 372/876 (42.47%), Query Frame = -3
Query: 1007 VLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYAN-----------INKDTIDLVSQVFSTINEFVAG----NQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQ--MIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARL--------YDLDP--NLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDY-LQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFA---FGLVHNVLCGFLLFTYFLADHPSPPRI------QYYFILIKRRLK-QNELDPADEDIIQQ---GDEGCKMRSH---LISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAII------------------------------GFAFFRSGFNTEK----------------------NLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKI---DELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEK 3319
+L+ L +C+ + LQ +LR Q +N ++NLV E +QFL+++ + IN+D + LV Q T+ E+ G NQ VT N I IL + P C +++LK N L+++++E + D E R++ +RP+ + I ++ ++E ++ + EVG + Y + +L + L P + +++ + S + + + ++ +Y+ ++ IE+++ D ++++ F + + EE K + ++ +K+ DF D S + N++ +Q++ + P+ +F+ LW GS +FN++ + N + FF P E + + L+ +L F + F + P I Y++ I L L+ ++ + G+ G +R + ++ + Y+ + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+ G A F + +K CD+L C V+VM GL VGD+ P E F V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I E L + L++H S+ +E K E + ++R +++ GF+ + + +
Sbjct: 1872 ILRFLQLLCENHNRDLQNFLRCQ-NNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIVTHESNGIDIITALILNDIS-PLCKYRMDLVLQLKDNASKLLLALMESRH--------------DSENAERILI--------------SLRPQELVD------VIKKAYLQEEERENSEVSPREVGHNIYILALQLSRHNKQLQHLLKPVRRIQEEEAEGISSMLSLNNKQLSQMLKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPAICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRRLRSMPLIYWFSRRMTLW------------------------GSI--SFNLAVFINIIIAFFY-------PYVEGASTGVLGSPLISLLFWILICFSIAALFTKRYSVRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPGNHSRASPLGMPHGAATFMGTCSGDKMDCVSEVSVPEILEEDEEPDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRK--PSKDES---LFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTSQLNELK---EQMTEQRKRRQRLGFVDVQNCMSR 2670
BLAST of SMED30029683 vs. Ensembl Mouse
Match: Itpr2 (inositol 1,4,5-triphosphate receptor 2 [Source:MGI Symbol;Acc:MGI:99418]) HSP 1 Score: 222.631 bits (566), Expect = 4.462e-57 Identity = 362/1579 (22.93%), Postives = 639/1579 (40.47%), Query Frame = -3
Query: 4895 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAV----------DEESNV----------------------ILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQF------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLK--------------VHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIH-EQP---NILYVSTDCMKSWI------------ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG---------------DV--DDVRSLLDKLIGLIDGSRDLPFPPERQGKELSK--------------EKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKE--CERNEGLLKKKNPSSLACALYEGFNPYEKKPSA-VRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W------------------SDEQVNRMENIFSE------------------------LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSS--------AAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH--------------YLTQYILESPHELVYYLLTKPFPKH---LKTH 9013
IGD + LY E + +G++ ST ++ + H + N P D F++ NRY K+Y K + N +A L + + AAE E N +E R+ + V+Y VIQL + S+KY+ VN + +KN M VSL+ ++ + F I P +K++SEG+ + + D+++L + + G HAS LDN E+N + + I E ++GG V+LFH E E ++ DD +Q H+ +R + +A T TS+ A+ W+IE G W+ FRF+H T YLA +E NV + V D ++F+L + V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A T++K+ + F+ LLED + F A V +++ + ++ K + RQKL+R ++ + +L P + E + L+ V CY +L + RKN Y AK + ++Q+ + I L+ +NRK++++ I+ +I FV LR N R+L+ L LCV N I Q I + L + + + ++ E P +IL D + W+ A+ Q G D E + + QL+LF +C R I I+ LS + + E LP D+RA +C +++ + VD SVV + P + ++EY D ++ D+ F +++ +L E N E N L +V+ L L+ FG+Y D+ + S ++L DGS ++ G+ +++ + + IV +Q Q E +++ K +E+LQ IL+ + R++ ++ +K+ + N+ +PS+ P PSA V + + MF + T V++D +LI+L + YA + AL++L +S + + QA + +L++ ++++ + LR+ + W E+ N N+ S LI L ++ +QR+L + VV+++L + +TD ++ E V+ A L+ P Q + ++L++ L L+E+E T++ +F+NN +LC +I R + V H + E+L L IVK + G +K+ Q +VM ++ A++ + M E +E G + Y I+L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ ++ Y+ +E EI IW+ N ++ +L + + ES +V PF + L+TH
Sbjct: 11 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVHPEAGDLANPPKKFRD---CLFKVCPMNRYSAQKQYW-KAKQAKQGNHTEA---ALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNA-GQPLHASNVELLDN-PGCKEVNAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTC----DDYEKKQ-HIFLRTTLRQSA-TSATSSKAL--WEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTPKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKL-----ENGSITQNERRFVTKLLEDLI---FFVAD----VTNNGQDVLDVVIT--KPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVL-RHSQQDYRKNQEYIAKNFCVMQSQI----GYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSV---DLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRN---------DMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSVPDAQPIVHPSKQASPGEQ--EDVTVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGDNND----NGDPSASG-------TPDTLLPSALVPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSGSYENGDVGEGQAKGGEEANEESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKTDEKMNE-------VMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAE---TMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHV-EYLRFLQTIVKAD--GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGP--LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYV-----DTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQTH 1505 HSP 2 Score: 176.792 bits (447), Expect = 2.767e-43 Identity = 142/582 (24.40%), Postives = 259/582 (44.50%), Query Frame = -3
Query: 1025 KAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDG---SFDENFNI-----SKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR------------------------------------------------SGFNTEKNL--YCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 2575
+A K+Y ++ IE+++ D ++++ F + N + E K V +R +K+ DF ++ + N++++QKK NNP +F+ LW L+V +NL + + DG + F++ S+ FF PV ++ ++ + L G L +I + + R G R+ ++ Y+ A + + G + +F++F L ++V+ + L VI +VT+NG+S+I A+L ++++YL++IIGF F + +G E + CD+L C V+V+ GL VGD+ P E F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ +EHNMW Y++F + ++ +YT + +VA ++ E+ D+FP RA+ L + + DS ++I L + + + ++ K + +E + ++R K+ GFL +
Sbjct: 2137 EALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPMFSVLLWVAVAICTSMLFFFSKPV--------GIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNR----------------GTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNHGVPTMTLSSMMETCQKENCSPTIPSSNTAGEEGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRR--PSKDEP---LFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGS 2689
BLAST of SMED30029683 vs. Ensembl Mouse
Match: Itpr1 (inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]) HSP 1 Score: 212.231 bits (539), Expect = 6.013e-54 Identity = 350/1579 (22.17%), Postives = 623/1579 (39.46%), Query Frame = -3
Query: 4898 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN---------------------------------VILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFM------------LVNGKSVKARQKLLRNLRVIDLLVKLLNMPL-------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTER-------GQNIHEQPNILYVSTDCMKSWI------------ALHKFLQVDYPGYDDEK--VQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPER-----SFVYEYVGTKDQNKTTTS----DQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDG---SRDLPFPPERQGKE---------LSKEKKKIVQKYQQGDRYL-----------------QSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNE----------GLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDEQVNR------------------------------MENIFSELIEFCHLPKAP-EEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPFPKHLKT 9013
IGD LY E T+G++ ST ++ + + N P D F++ NRY K++ K A + DA L ++ AA+ E N E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D + ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA + + + ++ V E D ++F+L P + V SY R+ H+ + W+H+ DKE E++ M I G K D +A+ I V P R +F L ++ +L++ + E V ++ F+ +V K + RQKL+R ++ + KLL P G A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV I Q I + L + + + + + N L D + W+ ++ + Q G +++ + + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD V P + S + + D + + TS + A+ + + LRD + + + K E N L +V+ L L+ FG+Y + D+ L L+ ++D + P +G+E + + + Q +G +L KE +++ K +E+LQ ILN + R++ + FK E +E G ++ PS++ AL F E++ + E T + +D +L++L + Y + AL++L +S +Q+ QA + +L+T+ ++++ + + LR + K + DE ++ ++ I L + C A + QR+L + VV+E+L + EK T+ L + QNQ + +++++ L ++E A+T++ +F+NN LC +I R + V H + +++ L IVK E G +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L +Y+ E +V + PF T
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPEAGDLNNPPKKFRD---CLFKLCPMNRYSAQKQFW-KAAKPGANSTTDA---VLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTC-----DEHRKKQHVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKE---------EEKPVMLKI---GTSPLKED-------KEAFAIVPVSPAEVRDLDFANDASKVLGSI-AGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFGFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDV---DLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVC-----QRFPFSDK-EKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKR-EFDESNSQSSETSSGNSSQEGPSNVPGAL--DFEHIEEQAEGIFGGS----------EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDEPMDGASGENEHKKTEEGTSKPLKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIP-----YEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNV-QYIKFLQTIVKAE--GKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTT 1500 HSP 2 Score: 160.614 bits (405), Expect = 2.442e-38 Identity = 93/360 (25.83%), Postives = 171/360 (47.50%), Query Frame = -3
Query: 1025 RSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-----------------------------------------------------NTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 1930
R+ ++ + Y+ L G + +F++ L ++V+ + L VI +VT+NG+S+I A+L ++++YL++I+G+ FF+ F +K C++L C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+ F + ++ + +YT + +VA +++E+ D+FP RA+ L + D + +++ L + + + + + + ++ + ++R QK+ G L +
Sbjct: 2383 RAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGH 2737
BLAST of SMED30029683 vs. Ensembl Mouse
Match: Itpr1 (inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]) HSP 1 Score: 211.46 bits (537), Expect = 1.004e-53 Identity = 350/1579 (22.17%), Postives = 623/1579 (39.46%), Query Frame = -3
Query: 4898 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN---------------------------------VILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFM------------LVNGKSVKARQKLLRNLRVIDLLVKLLNMPL-------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTER-------GQNIHEQPNILYVSTDCMKSWI------------ALHKFLQVDYPGYDDEK--VQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPER-----SFVYEYVGTKDQNKTTTS----DQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDG---SRDLPFPPERQGKE---------LSKEKKKIVQKYQQGDRYL-----------------QSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNE----------GLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDEQVNR------------------------------MENIFSELIEFCHLPKAP-EEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPFPKHLKT 9013
IGD LY E T+G++ ST ++ + + N P D F++ NRY K++ K A + DA L ++ AA+ E N E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D + ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA + + + ++ V E D ++F+L P + V SY R+ H+ + W+H+ DKE E++ M I G K D +A+ I V P R +F L ++ +L++ + E V ++ F+ +V K + RQKL+R ++ + KLL P G A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV I Q I + L + + + + + N L D + W+ ++ + Q G +++ + + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD V P + S + + D + + TS + A+ + + LRD + + + K E N L +V+ L L+ FG+Y + D+ L L+ ++D + P +G+E + + + Q +G +L KE +++ K +E+LQ ILN + R++ + FK E +E G ++ PS++ AL F E++ + E T + +D +L++L + Y + AL++L +S +Q+ QA + +L+T+ ++++ + + LR + K + DE ++ ++ I L + C A + QR+L + VV+E+L + EK T+ L + QNQ + +++++ L ++E A+T++ +F+NN LC +I R + V H + +++ L IVK E G +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L +Y+ E +V + PF T
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPEAGDLNNPPKKFRD---CLFKLCPMNRYSAQKQFW-KAAKPGANSTTDA---VLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTC-----DEHRKKQHVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKE---------EEKPVMLKI---GTSPLKED-------KEAFAIVPVSPAEVRDLDFANDASKVLGSI-AGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFGFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDV---DLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVC-----QRFPFSDK-EKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKR-EFDESNSQSSETSSGNSSQEGPSNVPGAL--DFEHIEEQAEGIFGGS----------EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDEPMDGASGENEHKKTEEGTSKPLKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIP-----YEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNV-QYIKFLQTIVKAE--GKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTT 1500 HSP 2 Score: 160.614 bits (405), Expect = 2.568e-38 Identity = 93/360 (25.83%), Postives = 171/360 (47.50%), Query Frame = -3
Query: 1025 RSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-----------------------------------------------------NTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 1930
R+ ++ + Y+ L G + +F++ L ++V+ + L VI +VT+NG+S+I A+L ++++YL++I+G+ FF+ F +K C++L C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+ F + ++ + +YT + +VA +++E+ D+FP RA+ L + D + +++ L + + + + + + ++ + ++R QK+ G L +
Sbjct: 2382 RAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGH 2736
BLAST of SMED30029683 vs. Ensembl Mouse
Match: Itpr2 (inositol 1,4,5-triphosphate receptor 2 [Source:MGI Symbol;Acc:MGI:99418]) HSP 1 Score: 202.216 bits (513), Expect = 6.072e-51 Identity = 355/1579 (22.48%), Postives = 625/1579 (39.58%), Query Frame = -3
Query: 4895 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAV----------DEESNV----------------------ILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQF------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLK--------------VHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIH-EQP---NILYVSTDCMKSWI------------ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG---------------DV--DDVRSLLDKLIGLIDGSRDLPFPPERQGKELSK--------------EKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKE--CERNEGLLKKKNPSSLACALYEGFNPYEKKPSA-VRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W------------------SDEQVNRMENIFSE------------------------LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSS--------AAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH--------------YLTQYILESPHELVYYLLTKPFPKH---LKTH 9013
IGD + LY E + +G++ ST ++ + H + N P D F++ NRY K+Y K + N +A L + + AAE E N +E R+ + V+Y VIQL + S+KY+ VN + +KN M VSL+ ++ + F I P +K++SEG+ V + N + + F SY E ++GG V+LFH E E ++ DD +Q H+ +R + +A T TS+ A+ W+IE G W+ FRF+H T YLA +E NV + V D ++F+L + V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A T++K+ + F+ LLED + F A V +++ + ++ K + RQKL+R ++ + +L P + E + L+ V CY +L + RKN Y AK + ++Q+ + I L+ +NRK++++ I+ +I FV LR N R+L+ L LCV N I Q I + L + + + ++ E P +IL D + W+ A+ Q G D E + + QL+LF +C R I I+ LS + + E LP D+RA +C +++ + VD SVV + P + ++EY D ++ D+ F +++ +L E N E N L +V+ L L+ FG+Y D+ + S ++L DGS ++ G+ +++ + + IV +Q Q E +++ K +E+LQ IL+ + R++ ++ +K+ + N+ +PS+ P PSA V + + MF + T V++D +LI+L + YA + AL++L +S + + QA + +L++ ++++ + LR+ + W E+ N N+ S LI L ++ +QR+L + VV+++L + +TD ++ E V+ A L+ P Q + ++L++ L L+E+E T++ +F+NN +LC +I R + V H + E+L L IVK + G +K+ Q +VM ++ A++ + M E +E G + Y I+L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ ++ Y+ +E EI IW+ N ++ +L + + ES +V PF + L+TH
Sbjct: 11 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVHPEAGDLANPPKKFRD---CLFKVCPMNRYSAQKQYW-KAKQAKQGNHTEA---ALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNVNAVN------------------------------CNTSWKITLFMKFSSYR-----EDVLKGGDVVRLFHAEQEKFLTC----DDYEKKQ-HIFLRTTLRQSA-TSATSSKAL--WEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTPKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKL-----ENGSITQNERRFVTKLLEDLI---FFVAD----VTNNGQDVLDVVIT--KPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVL-RHSQQDYRKNQEYIAKNFCVMQSQI----GYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSV---DLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRN---------DMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSVPDAQPIVHPSKQASPGEQ--EDVTVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGDNND----NGDPSASG-------TPDTLLPSALVPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSGSYENGDVGEGQAKGGEEANEESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKTDEKMNE-------VMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAE---TMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHV-EYLRFLQTIVKAD--GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGP--LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYV-----DTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQTH 1472 HSP 2 Score: 176.407 bits (446), Expect = 4.557e-43 Identity = 146/592 (24.66%), Postives = 265/592 (44.76%), Query Frame = -3
Query: 1025 KAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGL-VHNVLCGFLLFTYFLADHPSPPRIQYYFI-LIKRRLKQNELDP-----ADEDIIQQ--------GDEGCKMRSH---LISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR------------------------------------------------SGFNTEKNL--YCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 2575
+A K+Y ++ IE+++ D ++++ F + N + E K V +R +K+ DF ++ + N++++QKK NNP +F+ LW L+V +NL + + DG E S MF+ L V +C +LF + P I+ + + ++ R + L P ++ + G+ G R + ++ Y+ A + + G + +F++F L ++V+ + L VI +VT+NG+S+I A+L ++++YL++IIGF F + +G E + CD+L C V+V+ GL VGD+ P E F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ +EHNMW Y++F + ++ +YT + +VA ++ E+ D+FP RA+ L + + DS ++I L + + + ++ K + +E + ++R K+ GFL +
Sbjct: 2104 EALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGD-----------------------------EGTLSPMFSVLLWVAVAICTSMLFFF-----SKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNHGVPTMTLSSMMETCQKENCSPTIPSSNTAGEEGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRR--PSKDEP---LFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGS 2656
BLAST of SMED30029683 vs. UniProt/SwissProt
Match: sp|P70227|ITPR3_MOUSE (Inositol 1,4,5-trisphosphate receptor type 3 OS=Mus musculus OX=10090 GN=Itpr3 PE=1 SV=3) HSP 1 Score: 227.639 bits (579), Expect = 8.767e-58 Identity = 345/1573 (21.93%), Postives = 651/1573 (41.39%), Query Frame = -3
Query: 4880 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIED-ENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN-------------------------------VILVKESRDPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALK---DKEYKR------QQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLE----------------CYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL-------TERGQNIHEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKD-----LVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID---------------GSRDLPFPPERQGKELS----KEKKKI---------VQKYQQGDRY-LQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSD-------------------------------------EQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDH--VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHY-------------LTQYILESPHELVYYLLTKPFPKH---LKTHLTCSI 9013
IGD + LY E + +G++ ST ++ + N P D F++ NRY K+Y + +D E + D L + + AA+ E N E ++ V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + I P +K++S G+ V + D++IL + + G HAS + L + E+N + + I D E ++GG V+LFH E E ++ D ++ + +R + +A + +SN+ W++E G W+ +RF+H T YLA +E + ++ V D ++F+L P +Q ++ V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A ++K+ + + F+ LLED + F + V + + + M+ K + RQKL+R ++ + +L P + E V LE CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + E Q+ HE +I Y + +W ++ + Q G +D+ + + QL LF +C R I I+K L E FL + E+LP D+RA +C +++ + VD + +V + + ++ + T K S+ A++D + + D++ + E + E N+L +V+ L + L+ FG+Y ++ L L+G+ID G +++ + G +S K+ + V +Q DR + E + ++ K LE+LQ ILN + R++ ++ FK+ E E + + + +G P +A + ++ MF + ++ +++D +L++L + Y + AL++L +S +Q+ + +L++ ++ + ++ LR M + W D E ++ I L + C + E+ QR+L + + V++++L + ++D+++ E T + L+K P Q + ++L + L L+E+E T++ +F+NN LC +I + V L A H + ++LD L ++K E G +K+ Q ++M + + +S A++L+ R+ V EDH + Y ISL++LL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L + + + PF ++ L+TH T +
Sbjct: 10 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADV---VLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHAS-NYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTC-----DEYRGKLQVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQND-----RRFVIQLLEDLV---FFVSD----VPNNGQNVLDIMVT--KPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPL--VRLEELSDQKNAPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGMMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQS-HEYLSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISKQLGV---ELLFLCMADEMLPFDLRASFCHLMLHVHVD-RDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFASTMEFVEDYLNNVVSEAVPF--ANDEKNILTFEVVSLAHNLIYFGFYS-FSELLRLTRTLLGIIDCIQAPAAMLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPAGVGVPEQLDRSKFEDNEHTVVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDSGA-------DGTAPAFDSSTATMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLLHLTMHDYPSLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSVKGEEVEAGATKDKKERPSDEEGFLQPHGEKSSENYQIVKGILERLNKMCGV---GEQMRKKQQRLLKNMDAHKVMLDLLQIPYDKSDNKMLEILRYTHQFLQKFCAGN-------PGNQALLHKHLQLFLTPGLLEAE---TMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHV-QYLDFLHTVIKAE--GKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGV------EDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVTVVTHEDCITEVKMAYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFTLDMALVCNKREKRLSDPTLEKYVLTVVLDTISAFFSSPFSENSTSLQTHQTIVV 1499 HSP 2 Score: 128.257 bits (321), Expect = 1.082e-27 Identity = 132/566 (23.32%), Postives = 246/566 (43.46%), Query Frame = -3
Query: 1007 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHN---VLCGFLLFTYFLADHPSPPRI------QYYFILIKRRLK-QNELDPADEDIIQQ---GDEGCKMRSH---LISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAII------------------------------GFAFFRSGFNTEK----------------------NLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKI---DELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEK 2476
+ EE K + ++ +K+ DF D S + N++ +Q++ + P+ +F+ LW GS +FN++ + N + FF P E + + L+ +L F + F + P I Y++ I L L+ ++ + G+ G +R + ++ + Y+ + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+ G A F + +K CD+L C V+VM GL VGD+ P E F V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I E L + L++H S+ +E K E + ++R +++ GF+ + + +
Sbjct: 2146 LTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRRLRSMPLIYWFSRRMTLW------------------------GSI--SFNLAVFINIIIAFFY-------PYVEGASTGVLGSPLISLLFWILICFSIAALFTKRYSVRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPGNHSRASPLGMPHGAATFMGTCSGDKMDCVSEVSVPEILEEDEEPDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRK--PSKDES---LFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTSQLNELK---EQMTEQRKRRQRLGFVDVQNCMSR 2670
BLAST of SMED30029683 vs. UniProt/SwissProt
Match: sp|Q63269|ITPR3_RAT (Inositol 1,4,5-trisphosphate receptor type 3 OS=Rattus norvegicus OX=10116 GN=Itpr3 PE=1 SV=1) HSP 1 Score: 223.402 bits (568), Expect = 1.794e-56 Identity = 343/1570 (21.85%), Postives = 650/1570 (41.40%), Query Frame = -3
Query: 4889 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQDR---NQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIED-ENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN-------------------------------VILVKESRDPRTVFKLHP-VIQDSEE-VTFESYARIEHVLSGNWLHALK---DKEYKR------QQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLE----------------CYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL-------TERGQNIHEQPNILYVSTDCMKSWI---------ALHKFLQVDYPG--YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKD-----LVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID---------------GSRDLPFPPERQGKELS----KEKKKI---------VQKYQQGDRY-LQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSD-------------------------------------EQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS----------YSSAAYILEQPMETREAVLKEELGEDH--VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHY-------------LTQYILESPHELVYYLLTKPFPKH---LKTHLT 9013
IGD + LY E + +G++ ST ++ + N P D F++ NRY K+Y + +D E + D L + + AA+ E N E ++ V+YG VIQL + S+KY+ VN + +KN M V+L+ ++ + I P +K++S G+ V + D++IL + + G HAS + L + + E+N + + I D E ++GG V+LFH E E ++ D ++ + +R + +A + +SN+ W++E G W+ +RF+H T YLA +E + ++ V D ++F+L P +Q ++ V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A ++K+ + + F+ LLED + F + V + + + M+ K + RQKL+R+ ++ + +L P + E V LE CY +L + RKN + AK + ++Q+ + I L+ +NRK++++ I+K ++ FV +R N R+L+ L LCV N + I Q I + L + + E Q+ HE +I Y + +W ++ + Q G +D+ + + QL LF +C R I I+K L E FL + E+LP D+RA +C +++ + VD + +V + + ++ + T K S+ A++D + + D++ + E + E N+L +V+ L + L+ FG+Y ++ L L+G+ID G +++ + G +S K+ + V +Q DR + E + ++ K LE+LQ ILN + R++ ++ FK+ E E + + + +G P +A + ++ MF + ++ +++D +L++L + Y + AL++L +S +Q+ + +L++ ++ + ++ LR M + W D E ++ I L + C + E+ QR+L + + V++++L + + D+++ E T + L+K P Q + ++L + L L+E+E T++ +F+NN LC +I + V H + ++LD L ++K E G +K+ Q ++M + + +S A++L+ R+ V EDH + Y ISL++LL+ CAEG+N Y E C ++L +ED+++V+ H + +K ++ ++ Y+ +E EI IW N ++ L +Y+L + + + PF ++ L+TH T
Sbjct: 10 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRD---CLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADV---VLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHAS-NYELSDNVGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTC-----DEYRGKLQVFLRTTLRQSATSATSSNA---LWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGPGAQSRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQND-----RRFVIQLLEDLV---FFVSD----VPNNGQNVLDIMVT--KPNRERQKLMRDENILKQIFGILKAPFRDKGGEGPL--VRLEELSDQKNAPYQYMFRLCYRVL-RHSQEDYRKNQEHIAKQFGMMQSQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQS-HEYLSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISKQLGV---ELLFLCMADEMLPFDLRASFCHLMLHVHVD-RDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFASTMEFVEDYLNNVVGEAVPF--ANDEKNILTFEVVSLAHNLIYFGFYS-FSELLRLTRTLLGIIDCIQAPAAVLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPTGVGVPEQLDRSKFEDNEHTVVMETKLKILEILQFILNVRLDYRISYLLSVFKK-EFVEVFPMQDSGA-------DGTAPAFDSSTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLLHLTMHDYPPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSVKGEEGEAGASKDKKERPSDEEGFLQPHGEKSSENYQIVKGILERLNKMCGV---GEQMRKKQQRLLKNMDAHKVMLDLLQIPYDKNDNKMMEILRYTHQFLQKFCAGN-------PGNQALLHKHLQLFLTPGLLEAE---TMQHIFLNNYQLCSEISEPVLQHFVHCWPTHGRHV-QYLDFLHTVIKAE--GKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGV------EDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYV-----DTEVEMKEIYTSNHIWTLFENFTLDMALVCNKREKRLSDPTLEKYVLTVVLDTISAFFSSPFSENSTSLQTHQT 1496 HSP 2 Score: 127.102 bits (318), Expect = 2.171e-27 Identity = 131/566 (23.14%), Postives = 246/566 (43.46%), Query Frame = -3
Query: 1007 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHN---VLCGFLLFTYFLADHPSPPRI------QYYFILIKRRLK-QNELDPADEDIIQQ---GDEGCKMRSH---LISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAII------------------------------GFAFFRSGFNTEK----------------------NLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKI---DELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEK 2476
+ EE K + ++ +K+ DF D S + N++ +Q++ + P+ +F+ LW GS +FN++ + N + FF P E + + L+ +L F + F + P I Y++ I L L+ ++ + G+ G +R + ++ + Y+ + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+ G A F + +K CD+L C V+VM GL VGD+ P E F V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW+Y++F + ++ DYT + +VA ++K + D+FP RA+ L + + + ++I E L + L++H ++ +E K E + ++R +++ GF+ + + +
Sbjct: 2146 LTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRRLRSMPLIYWFSRRMTLW------------------------GSI--SFNLAVFINIIIAFFY-------PYVEGASTGVLGSPLISLLFWILICFSIAALFTKHYSVRPLIVALVLRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPGNHSRASTLGMPHGAATFMGTCSGDKMDCVSEVSVPEILEEDEELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRK--PSKDES---LFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTAQLNELK---EQMTEQRKRRQRLGFVDVQNCMSR 2670
BLAST of SMED30029683 vs. UniProt/SwissProt
Match: sp|Q9Z329|ITPR2_MOUSE (Inositol 1,4,5-trisphosphate receptor type 2 OS=Mus musculus OX=10090 GN=Itpr2 PE=1 SV=4) HSP 1 Score: 222.631 bits (566), Expect = 3.121e-56 Identity = 362/1579 (22.93%), Postives = 639/1579 (40.47%), Query Frame = -3
Query: 4895 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAV----------DEESNV----------------------ILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQF------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLK--------------VHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIH-EQP---NILYVSTDCMKSWI------------ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG---------------DV--DDVRSLLDKLIGLIDGSRDLPFPPERQGKELSK--------------EKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKE--CERNEGLLKKKNPSSLACALYEGFNPYEKKPSA-VRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W------------------SDEQVNRMENIFSE------------------------LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSS--------AAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH--------------YLTQYILESPHELVYYLLTKPFPKH---LKTH 9013
IGD + LY E + +G++ ST ++ + H + N P D F++ NRY K+Y K + N +A L + + AAE E N +E R+ + V+Y VIQL + S+KY+ VN + +KN M VSL+ ++ + F I P +K++SEG+ + + D+++L + + G HAS LDN E+N + + I E ++GG V+LFH E E ++ DD +Q H+ +R + +A T TS+ A+ W+IE G W+ FRF+H T YLA +E NV + V D ++F+L + V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A T++K+ + F+ LLED + F A V +++ + ++ K + RQKL+R ++ + +L P + E + L+ V CY +L + RKN Y AK + ++Q+ + I L+ +NRK++++ I+ +I FV LR N R+L+ L LCV N I Q I + L + + + ++ E P +IL D + W+ A+ Q G D E + + QL+LF +C R I I+ LS + + E LP D+RA +C +++ + VD SVV + P + ++EY D ++ D+ F +++ +L E N E N L +V+ L L+ FG+Y D+ + S ++L DGS ++ G+ +++ + + IV +Q Q E +++ K +E+LQ IL+ + R++ ++ +K+ + N+ +PS+ P PSA V + + MF + T V++D +LI+L + YA + AL++L +S + + QA + +L++ ++++ + LR+ + W E+ N N+ S LI L ++ +QR+L + VV+++L + +TD ++ E V+ A L+ P Q + ++L++ L L+E+E T++ +F+NN +LC +I R + V H + E+L L IVK + G +K+ Q +VM ++ A++ + M E +E G + Y I+L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ ++ Y+ +E EI IW+ N ++ +L + + ES +V PF + L+TH
Sbjct: 11 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVHPEAGDLANPPKKFRD---CLFKVCPMNRYSAQKQYW-KAKQAKQGNHTEA---ALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNA-GQPLHASNVELLDN-PGCKEVNAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTC----DDYEKKQ-HIFLRTTLRQSA-TSATSSKAL--WEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTPKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKL-----ENGSITQNERRFVTKLLEDLI---FFVAD----VTNNGQDVLDVVIT--KPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVL-RHSQQDYRKNQEYIAKNFCVMQSQI----GYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSV---DLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRN---------DMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSVPDAQPIVHPSKQASPGEQ--EDVTVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGDNND----NGDPSASG-------TPDTLLPSALVPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSGSYENGDVGEGQAKGGEEANEESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKTDEKMNE-------VMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAE---TMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHV-EYLRFLQTIVKAD--GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGP--LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYV-----DTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQTH 1505 HSP 2 Score: 168.318 bits (425), Expect = 9.139e-40 Identity = 133/536 (24.81%), Postives = 235/536 (43.84%), Query Frame = -3
Query: 1025 NVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDG---SFDENFNI-----SKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE----KNLY----------------------------------------------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 2443
+R +K+ DF ++ + N++++QKK NNP +F+ LW L+V +NL + + DG + F++ S+ FF PV ++ ++ + L G L +I + + R G R+ ++ Y+ A + + G + +F++F L ++V+ + L VI +VT+NG+S+I A+L ++++YL++IIGF F + F E KN CD+L C V+V+ GL VGD+ P E F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ +EHNMW Y++F + ++ +YT + +VA ++ E+ D+FP RA+ L + + DS ++I L + + + ++ K + +E + ++R K+ GFL +
Sbjct: 2183 TTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPMFSVLLWVAVAICTSMLFFFSKPV--------GIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNR----------------GTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNHGVPTMTLSSMMETCQKENCSPTIPSSNTAGEEGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRR--PSKDEP---LFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGS 2689
BLAST of SMED30029683 vs. UniProt/SwissProt
Match: sp|P29995|ITPR2_RAT (Inositol 1,4,5-trisphosphate receptor type 2 OS=Rattus norvegicus OX=10116 GN=Itpr2 PE=1 SV=1) HSP 1 Score: 221.861 bits (564), Expect = 4.154e-56 Identity = 360/1578 (22.81%), Postives = 638/1578 (40.43%), Query Frame = -3
Query: 4895 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN--------------------------------VILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQF------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLK--------------VHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIH-EQP---NILYVSTDCMKSWI------------ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV---------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYG---------------DV--DDVRSLLDKLIGLIDGSRDLPFPPERQGKELSK--------------EKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKF-KECERNEGLLKKKNPSSLACALYEGFNPYEKKPSA-VRKQKLMIKELREMF---ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W------------------SDEQVNRMENIFSE------------------------LIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSV---ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSS--------AAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH--------------YLTQYILESPHELVYYLLTKPFPKH---LKTH 9013
IGD + LY E + +G++ ST ++ + H + N P D F++ NRY K+Y K + N +A L + + AAE E N +E R+ + V+Y +VIQL + S+KY+ VN + +KN M VSL+ ++ + F I P +K++SEG+ + + D+++L + + G HAS LDN E+N + + I E ++GG V+LFH E E ++ DD +Q H+ +R + +A T TS+ A+ W+IE G W+ FRF+H T YLA + + ++ V D ++F+L + V SY R+ H+ + W+ + D E +R T ED+ + + E+R +D +D A T++K+ + F+ LLED + F A V +++ + ++ K + RQKL+R ++ + +L P + E + L+ V CY +L + RKN Y AK + ++Q+ + I L+ +NRK++++ I+ +I FV LR N R+L+ L LCV N I Q I + L + + + ++ E P +IL D + W+ A+ Q G D E + + QL+LF +C R I I+ LS + + E LP D+RA +C +++ + VD SVV + P + ++EY D ++ D+ F +++ +L E N E N L +V+ L L+ FG+Y D+ + S ++L DGS ++ G+ +++ + + V +Q Q E +++ K +E+LQ IL+ + R++ ++ + KE N+G +PS+ P PSA V + + MF + T V++D +LI+L + YA + AL++L +S + + QA + +L++ ++++ + LR+ + W E+ N N+ S LI L ++ +QR+L + VV+++L + +TD ++ E V+ A L+ P Q + ++L++ L L+E+E T++ +F+NN +LC +I R + V H + E+L L IVK + G +K+ Q +VM ++ A++ + M E +E G + Y I+L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ ++ Y+ +E EI IW+ N ++ +L + + ES +V PF + L+TH
Sbjct: 11 IGDIVSLYAEGSVNGFI---STLGLVDDRCVVHPEAGDLTNPPKKFRD---CLFKVCPMNRYSAQKQYW-KAKQAKQGNHTEA---ALLKKLQHAAELEQKQNESENRKLLGEIVKYSKVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNA-GQPLHASNVELLDN-PGCKEVNAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTC----DDYEKKQ-HIFLRTTLRQSA-TSATSSKAL--WEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKTVRDGELPTSKKKHQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKL-----ENGSITQNERRFVTKLLEDLI---FFVAD----VTNNGQDVLDVVIT--KPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVL-RHSQQDYRKNQEYIAKNFCVMQSQI----GYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSV---DLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRN---------DMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSWPDAQPSVHPSKQASPGEQ--EDVTVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGENDG---NGDPSASG-------TPETLLPSALVPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSGSYENGDMGEGQAKGGEEANEESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKTDEKMNE-------VMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAE---TMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHV-EYLRFLQTIVKAD--GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGP--LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYV-----DTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQTH 1505 HSP 2 Score: 167.162 bits (422), Expect = 1.835e-39 Identity = 134/538 (24.91%), Postives = 235/538 (43.68%), Query Frame = -3
Query: 1025 NVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYN----------NSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE----KNLY----------------------------------------------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 2443
+R +K+ DF ++ + N++++QKK NNP +F+ LW L+V +NL + + DG DE ++ S+ FF PV ++ ++ + L G L +I + + R G R+ ++ Y+ A + + G + +F++F L ++V+ + L VI +VT+NG+S+I A+L ++++YL++IIGF F + F E KN CD+L C V+V+ GL VGD+ P E F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ +EHNMW Y++F + ++ +YT + +VA ++ E+ D+FP RA+ L + + DS ++I L + + + ++ K + +E + ++R K+ GFL +
Sbjct: 2183 TTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDG--DEGTLSPLFSALLWVAVAICTSMLFFFSKPV--------GIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNR----------------GTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNDGVPTMTLTSMLGTCPKENCSPTIPSSNAAGEGGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRR--PSKDEP---LFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEKILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGS 2689
BLAST of SMED30029683 vs. UniProt/SwissProt
Match: sp|Q9TU34|ITPR1_BOVIN (Inositol 1,4,5-trisphosphate receptor type 1 OS=Bos taurus OX=9913 GN=ITPR1 PE=1 SV=1) HSP 1 Score: 220.32 bits (560), Expect = 1.408e-55 Identity = 349/1576 (22.14%), Postives = 623/1576 (39.53%), Query Frame = -3
Query: 4898 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN---------------------------------VILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFM------------LVNGKSVKARQKLLRNLRVIDLLVKLLNMPL-------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTER-------GQNIHEQPNILYVSTDCMKSWI------------ALHKFLQVDYPGYDDEK--VQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPER-----SFVYEYVGTKDQNKTTTS----DQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDG---SRDLPFPPERQGKE---------LSKEKKKIVQKYQQGDRYL-----------------QSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKE---------CERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDEQVNR------------------------------MENIFSELIEFCHLPKAP-EEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPFPKHLKT 9013
IGD LY E T+G++ ST ++ + + N P D F++ NRY K++ K A + DA L ++ AA+ E N E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D + ++GG V+LFH E E ++ D ++ H+ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA + + + ++ V E D ++F+L P + V SY R+ H+ + W+H+ DKE E++ M I G K D +A+ I V P R +F L ++ +L++ + E V ++ F+ +V K + RQKL+R ++ + KLL P G A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV I Q I + L + + + + + N L D + W+ ++ + Q G +++ + + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD V P + S + + D + + TS + A+ + + LRD + + + K E N L +V+ L L+ FG+Y + D+ L L+ ++D + P +G+E + + + Q +G +L KE +++ K +E+LQ ILN + R++ + FK E + G ++ PS++ AL F E++ + E TT + +D +L++L + Y + AL++L +S +Q+ QA + +L+T+ ++++ + + LR + K + DE ++ ++ I L + C A + QR+L + VV+E+L + + E E + L A +P+ Q + +++++ L ++E A+T++ +F+NN LC +I R + V H + +++ L IVK E G +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ E EI +W+ N +I L +Y+ E +V + PF T
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRD---CLFKLCPMNRYSAQKQFW-KAAKPGANSTTDA---VLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTC-----DEHRKKQHVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKE---------EEKPVMLKI---GTSPVKED-------KEAFAIVPVSPAEVRDLDFANDASKVLGSI-AGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFGFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWVFWRDSNKEVRSKSVRELAQDAKEGQKEDRDVLGYYRYQLNLFARMCLDRQYLAINEISGQLDV---DLILRCMSDENLPSDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVC-----QRFPFSDK-EKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPTATAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL--DFEHIEEQAEGIFGGS----------EETTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDEAMDGASGENEHKKTEEGNNKSQQHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEK--AEDTMMQEIMRLAHEFLQNFCAGNHPN-QALLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNV-QYIKFLQTIVKAE--GKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYV-----DPEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTT 1500 HSP 2 Score: 158.303 bits (399), Expect = 8.379e-37 Identity = 95/359 (26.46%), Postives = 171/359 (47.63%), Query Frame = -3
Query: 1028 RSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFR------------------------------------SGFNT-----------------EKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLS 1930
R+ ++ + Y+ L G + +F++ L ++V+ + L VI +VT+NG+S+I +A+L ++++YL++I+G+ FF+ +G N +K C++L C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+ F + ++ + +YT + +VA ++KE+ D+FP RA+ L + D + +++ L + + + + + ++ + +R QK+ G L
Sbjct: 2343 RAMVLDVEFLYHLLXLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILMAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETSLPEASESLASEFLYSDVCRVETGENCSSPAPKEELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGLLSELKDQMTDQRKQKQRMGLLG 2696
BLAST of SMED30029683 vs. TrEMBL
Match: A0A267G7Y3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011719g6 PE=4 SV=1) HSP 1 Score: 2948.69 bits (7643), Expect = 0.000e+0 Identity = 1499/2760 (54.31%), Postives = 1985/2760 (71.92%), Query Frame = -3
Query: 1046 CIGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVL-------------------------------DADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLD-----NFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEES---NVILVKESRDPRTVFKLHPVIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQ---FLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKD-QNKTTTSDQY----------------AAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQ-GKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQ-VKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQ-PMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILK---EKKIWQFIGNLGEEIHYLTQYIL-ESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSE-DNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHIS----ATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQ----KVIKKEKNING------------KVKHTPKATFRQ-------------SDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNS-LPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQ-NELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNL-YCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKR 9016
CIGD+I LYCE+TDG+V+S ++ + FN L +YH R++P +IPDPQ++ FQ+ IQNRYKL+KKY + A+ D D R +QA+ AA AENVDN+AEQRRN K+VRYGE++QLK VF+ KY+HVNT TSQ DKNNM++SL+ +N K AQF+ILPRYKVKSEGE+VQ+ DQI LESIKSPGH+FH+S F + F+ SELNLGVEQ+GFTI+KS+ + E + RGGQFVQLFHKE+EAY+VAEGLFD VTE VHLRIREIDQLN RTL +S SA+TYWQ+E E +++ G+ LTWDQQFRFRH TTR YL V + S +V L +++ DP TVFK+HPV+QDS E+ FESYARIEHV++G WLHA+KDK Y+R++F EDE+SM A+RWDGGELR++ C DRRYDDAYTIQKV E+ FNF+AG+VP L++L++ R + L +KE +R+C A RE++ FMLVNG+ KARQKLLRNLRVIDLLV LL PL DE N KV E YDIL+TYM+G+SRKNALYFAKYIE F+TQM+DKSE++LKV +++VEL++DNRKIVDRIS QI FVE LR NE++ YLELLKVLCVCNGV I +NQ +IAQ+WLLED RGVY+T RGQNI +PN YVS D SW+ L F+Q D YD E V+ FL QLDLF A+C+GRNE CIRLITKDLSYL+WEE +L L SE LP + RAKYCE+IIGLFV+VGNNYSVV+ P+ F+YEY+GTKD +T++ +QY AAKDLVTIFP +RDWIA FLD+N M+AS++ +N+LIEQVL+LL++LVKFGYYG+V D+ LL L L+DG D+PFPP+R +E SKE+KK V +++Q +R+ +S ET AIV AK+AAL+VL +++ F+ NARLA F+ KFK+ E +E ++K+ L ALY+ F+P++ + SA++ QK M KELR MFE +++ V +T+ILI+LAHY+Y M QL+L++LN L+S K F A SLVL+T DSC VHREV KQVPLL+MM +SKW+ +Q ++E I SEL E CHLPKA EEPHPMNQR++ S NV+GVV +ILS ETD QLTEKY +T VLRKA++L+KA+ ++Y DVQNQ+F NLD +LRV+LVE +LA+ LKEVFVNNQ LCLKILPRQI +IV L AE+Q++APEFL+LL AIVKVEG GLALKRNQTLVMKYIMQ+YS Y+LEQ + R VL G H QYLISL++LL+TCAEGENRYIESLCQTI+SVE+IL +LN P + NHLK+PFL+Y+ +AY+K +++E+ + +I++ +K +W+++ +L E LT++I ++ + VY++ +PFPK L+ H C +C+ LV++D +PLKLN ENA++R++ED+FR HAS+HY+FD+V+ FL ++ + + + + D +SE+D++D LT S + LC+ L+ + +P L M+AC++ ++ KS+ TIMEPVVE IGKG K+ DT++QMK GN+EYY QE+ +N KLKT A N SL++ G NTV+AQLK SS+R+YT + G++ LPL +EFQ+H++CFI ++K E +Y++A LL+N L I+ + + A R + E+L IR LQ+LRA IHNEERKLPEDW+ R SEFR+K+GLKNI +IQNTLNSF LPHLA+ S +AKEVLSL +MLFNAN +Q+S+L YFL TKEEVFF+AVRNRLQ+S ANIKE+RLL++QQ +R+ +A+ QA +L TMTLG +A+++I+ +++ A + L+ Q + KK+ + G + A RQ +DG G N + D + EAE+ ISMKDDGY+ LVLK+LARICDGQH GLQ YLREQPDN+KSFNLVAEV QF+NV Y+NIN +TI+L+ Q+F+T+NEF AGNQENR VYDNKIIDYIN+ILR ++ +C + Q+ L+Q I NLV+S+IEEN+P+A I EVKDTLDKEA+YRVMTE YE + +S +G + + + KDE K+LK + +VGFS+Y I+ARLYD+DP +GKKD + L I+ +Q KAFKF+KKNS++IE++K LQK+HFR+RNKN++REEVKE +KWNVDR+S S KIRDFMDW+K+ILNDI YQKK ++NP+ T WL+WN++ T+++VI+NL+ML +AP G+ + +IS ++ +PD F N WK + +L W+ AF + + L +L +F+A+HP PP + + RL+Q + D +E+ +++ K+ L S TFYY +G + AG +YSPYFFAFHL+NIV+NNQ+L+GVI AVT NG SL+WV++LG+ ++YLYA+IGFA FR F + +L +C +L+ CFV+++RFGL+GDLFENL+P S ++F + + ++ ++FF+LI+TIGLNIIFGIIVDTFS+LRD KW AE+DMR+ CFICSRN+YDFEHHGQGF++HV EHNMW+YIFFFIHL+DT NDYTSLD+ V +LKE++F+FFPLNRALCL+AKDEDSTDSKIDELL NV L+ HQK E++ER+R+ EL RQK+WQ++
Sbjct: 28 CIGDYIGLYCEDTDGHVFSQNSCAAFNGLFVYHSCHRDRPVNIPDPQVLLFQVCIQNRYKLDKKYRKAVASNRQAAASAASQQQPQQQQTTETSPLTQPEQPEQQIAENDFDLRLHIEQARNAASAENVDNMAEQRRNLGKRVRYGEIVQLKHVFTGKYVHVNTNHTSQHDKNNMLLSLHEYNSKNAQFRILPRYKVKSEGEHVQLLDQISLESIKSPGHYFHSSKGFKIGPESRPTFV--SELNLGVEQTGFTIIKSHGFSGDHEAYARGGQFVQLFHKELEAYVVAEGLFDQDVTEDVHLRIREIDQLNPRTLHSSTSAVTYWQVEPESTVLDGEVLTWDQQFRFRHATTRKYLCVKQASEAYSVTLTEDATDPHTVFKMHPVLQDSPELKFESYARIEHVITGCWLHAIKDKSYQRKEFLNMEDEKSMRALRWDGGELREITCCFDRRYDDAYTIQKVDSEHVMNFNFVAGVVPTLQDLIDARQIGRPLTSKETFRICHALRELRNFMLVNGEPCKARQKLLRNLRVIDLLVTLLKFPLKAVQDEHNLTKVFSEAYDILHTYMMGNSRKNALYFAKYIEFFQTQMVDKSELALKVTKMLVELMKDNRKIVDRISNAQIEVFVELLRKNEHHSYLELLKVLCVCNGVAITENQNFIAQKWLLEDTRGVYMTNRGQNIDRKPNETYVSYDQQHSWLPLVDFVQPD--EYDTEAVERCLFLHTQLDLFIALCHGRNEDCIRLITKDLSYLTWEEAYLGLSSESLPHEFRAKYCEIIIGLFVNVGNNYSVVESPQLCFIYEYIGTKDFTYQTSSPEQYKQGRKVGEPSRLEQQRAAKDLVTIFPVIRDWIAEFLDQNRMMVASQVANNILIEQVLKLLHYLVKFGYYGEVHDLARLLPALRNLLDGQNDIPFPPDRMPAREFSKERKKAVLRFKQTERFRRSPETQAIVRAKHAALQVLDLVMTFQENARLASFIKKFKDSEISEVATRRKHIHPLVPALYDSFDPFDTRKSALQVQKRMKKELRIMFEESSRHVDNIALTSILIDLAHYEYDPMVQLSLQLLNKLHSAKSSMFNLAVNSLVLITPDSCRVHREVGKQVPLLKMMIRSKWTSDQAVKIETILSELRELCHLPKAEEEPHPMNQRLMLSHNVLGVVFDILSTETDVQLTEKYHETVGVLRKAVRLMKALTIRYEDVQNQVFNNLDSMLRVRLVEPDLALALKEVFVNNQELCLKILPRQISRIVGLVAENQERAPEFLELLSAIVKVEGPGLALKRNQTLVMKYIMQNYSKVGYVLEQCTTKDRMEVLNGNRGASHCQYLISLVDLLATCAEGENRYIESLCQTIISVEEILCILNDPNVENHLKKPFLRYMFYAYMKTSGSTAENRSPDIIQDRYQKLVWEYVRHLTLEFDGLTRWIRNDAARDTVYFMSMRPFPKILRLHDACPLCSTLVAEDETQPLKLNLENAVVRMREDDFRGHASLHYVFDAVLPFLQAFANKFYQTEEDKDTQSERDMFDRLTLSAIGLCSELAAIVVEPRILTQMVACLSALVRKSSHRPTIMEPVVENIGKGTKLQDTVSQMKSGNKEYYEQEIILNSKLKTLAVNMSLLWGGQNTVRAQLKYSSDREYTVIGGEESLPLDEEFQDHVRCFISAGSRKPEGRYRLAGLLVNGLRITAVSSTASASHAAAAAADPGAGGRGDTERLAIRILQILRAFIHNEERKLPEDWEVRMSEFRVKRGLKNIAEIQNTLNSFDLMKHALPHLASTSGLVAKEVLSLLGIMLFNANEKVQQSMLKYFLNTKEEVFFFAVRNRLQVSTANIKEKRLLISQQKARQMDARSQADDLKATMTLGVKALQQIQQYHVEMKIEQANSDLTRRVSLTQMQSASITKKKSGVGGVASGSNGGSNGGSNGGSTSAAGRQVAFANGIKGGKDAADGLMKGSNGTDRMDGDQSSAHHLEAEK----------------------------ISMKDDGYVGLVLKVLARICDGQHKGLQNYLREQPDNIKSFNLVAEVSQFINVAYSNINSETIELLVQLFTTVNEFCAGNQENRAAVYDNKIIDYINFILRTSDFENCELDQIASLRQAIANLVVSLIEENSPEAAVIGREVKDTLDKEALYRVMTECYEYCQRDSSGKEG---------------WLRRLLKKDENKELKDAIFDVGFSFYTIIARLYDIDPAMGKKDSD---------------PYGRELRISDSQMKAFKFFKKNSMTIEIVKDSNLQKIHFRVRNKNVLREEVKEKLKWNVDRNSSSTKIRDFMDWTKAILNDIHYQKKVLSNPLTIALTRLWLIWNHSATLVAVIINLIMLIGLEAPPGGANTPSLDISADESAPVPDAFFNTTGQWKADYPSLPDWLMAFAYILDALSIIILLAFFVANHPRPPDLAR----LAWRLRQLRQKDQEEENELRESGGQDKLSVRLFSIATFYYIVFVGCAFAGTFYSPYFFAFHLLNIVNNNQMLRGVIQAVTTNGLSLVWVSVLGIAIMYLYAVIGFAKFRIAFRPDDSLMFCGTLYQCFVTILRFGLIGDLFENLVPPSSHRNFDEYVWMALFSITFFVLISTIGLNIIFGIIVDTFSQLRDKKWMAETDMRNCCFICSRNNYDFEHHGQGFDHHVRTEHNMWAYIFFFIHLEDTATNDYTSLDLHVHKMLKEERFEFFPLNRALCLSAKDEDSTDSKIDELLSNVKDLVQHQKEEEAERRRWVELNRQKKWQQK 2721
BLAST of SMED30029683 vs. TrEMBL
Match: A0A267E835 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032795g1 PE=4 SV=1) HSP 1 Score: 2914.41 bits (7554), Expect = 0.000e+0 Identity = 1471/2603 (56.51%), Postives = 1937/2603 (74.41%), Query Frame = -3
Query: 1046 DTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN---VILVKESRDPRTVFKLHPVIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDD-EKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQ-NKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPER--QGK-ELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQ-VKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQ-PMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEK---KIWQFIGNLGEEIHYLTQYIL-ESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSE-DNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNN-SKTR---QKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTV---AKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRL---KQNELDPADEDIIQQGDEGC-KMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKR 8776
+ +Q +QA+ AA AENVDN+AEQ+RNQ K+VRYGE+IQLK VF+ K++HVNT QTSQ DKNNM++SL+ N K AQF+ILPRYKVKSEGEYVQ+ DQ ESIKSPGHFFHAS F ++ + SELNLGV+Q+GFTI+KS++H+ E E F RGGQFVQLFHKE+EAY+VAEGLFDD VTE VHLRIRE+DQLNARTLR S SAITYWQ+E EK++++GD LTWDQQFRFRH TTR YL + +E + V L+ ++ DP TVFKLHPV+Q++ E+ FESYARIEHV++G+WLHA+KDK Y+R++F EDE+SM A+RWDGGELR+V C DRRYDDAYTI+KV + FNF+AG+VPFL+NL+ R K L KE + +C A +E+++FM+VNG+ K +QKLLRNLRVIDLLV LL PL G DE N +V YDIL+TYM+G+SRKNALYFAKYIE F+TQM+DKS+++LKV +++VEL++DNRKIVDRISK QI+ FV+ LR NE+Y YLELLKVLCVCNGV I DNQ+YIAQ+WLLED RG+YL+ERGQNI +PN YVSTD MK+W L F+Q D + E+ FL QLDLF A+C+GRNE CIRLITKDLSYL+WEE +L L S+ LP RAKYCE++IGLFV+VGNNYSVV+ P+ SF+YEYVGTKD T DQYAAKDL+T+FP +RDWI FLD+N +M+A++I +NMLIEQVLRLL++LVKFGYYGDV D+ LL L L++G D+PF P++ QG+ + +K+ KKIVQ+++Q DRY +S +T AIVNAK+AAL VL +++ F+ NARLA F++KFK+CE +E + KK+ + ALY F+ ++ K SA +KQ + KELR MF+ +++ + D +T ILI+LA+Y+Y M +L+L++LN LYS K FQ A SLVL T DSC VHREV+KQVPLLRM A+SKW+ EQ +M+ I EL E CHLPKA EEPHPMNQR++ S N++ V+ +IL+ ETD+QL+E Y +T VLRKA++LLKA+ L+YPDVQ Q+F +LD LLRV+LVES+LA+ LKEVF NNQ LCL++LP+QI +IV L AEHQ++APEFL+LL AIVKVEG GLALKRNQTLVMKYIMQ+YS AYILEQ ++ R VL G DH QYL+S I+LL+TCAEGENRYIESLCQTILSV++IL +LN P++ NHLK+PFL+Y+ FAY+K + E+ + +I+ + +IW ++ +LG E+ L +I ++ + VY++ KPFPK ++ H TC +C+ LVS+D KPLKLN ENA+++++ED++R H+S+HY+FD+V FL ++++ ++ D + D ++E++++D +T V C L+ + +P L M++C++ ++ +S+ P +IMEPVVE IGKG K+ DT++QMK GN+EYY QE+ +N KLK+ A N SL++ GHNTV+AQLK++SNR+YTT+ GD+ LPL +EFQ+H++C I ++K E +YK+ LL+N L I ATT+ ++ TT K R EQE+L +R LQ+LRA +HNEERKLP DW+ RT+EFR+KKGL+NI DIQ TLNSF+ LPHLA+ S +AKEVLSL MMLFNAN +Q+S+L+YFL TKEEVFFYAVRNRLQ+S ANIKERRLL++QQ +R+ EA+ QA+NL TMTLG +A+++I+ +++ A N L+ S T+ Q ++ K + +G TP + + G + +N L G E +A + A ++ E E + DE ISMKDDGYI LVLK+LA ICDGQH GLQ YLREQPDN+KSFN+VAEV QF+NV Y+NIN DTIDL+ Q+FST+NEF AGNQENR TVYDNKIIDYIN+ILR ++ C Q+++L+Q I NLVIS+IEEN+P+A IA EVKDTLDK A+YR M+E YE + ++ K + + K+E ++LK + EVGF++Y ILARLYD+DP +GKKD + L I+ QQKAFKF+KKN+++IE+LK D LQKVHFR+RNKN++REE+KE +KWNVDRSSPS KIRDFMDW+K+IL DI YQKK ++NP T WL+WN+A T+ +VI+NL+ML +A + + + ++P N WK +FE+L+ W AF ++L +L +F+A+HP PP ++ ++R E DPA D +G EG K+ +L S T YY + + AG +Y PYFFAFHL+N+V+NNQLLQGVI AVT NG SLIWV++LG+ ++YL++++ FA R GF ++C L CFV+V+RFGL+GDLFEN++P + +F +F + I+H+ FFILITT+GLNIIFGIIVDTFSELR++KWTAE DMRD CFICSR++YDFEHHGQGF+YHV NEHNMW+YIFFFIHLQDT NDYTSL++ V LL E+K+DFFP+NRALCL+AKDEDST+SKIDELL++V L+ HQK E++ERKR+ EL RQ++WQ+R
Sbjct: 174 EAKQHFEQARCAANAENVDNMAEQKRNQGKRVRYGEIIQLKHVFTGKFVHVNTNQTSQYDKNNMLLSLHEFNSKNAQFRILPRYKVKSEGEYVQLLDQTSFESIKSPGHFFHASHGFPIEAGRIVSELNLGVDQTGFTILKSHTHYGEFEAFARGGQFVQLFHKELEAYVVAEGLFDDEVTEGVHLRIREVDQLNARTLRQSTSAITYWQVESEKTMLNGDILTWDQQFRFRHATTRKYLCLQQEGSGYVVSLLDDATDPHTVFKLHPVLQETAELKFESYARIEHVITGSWLHAIKDKAYERREFLNMEDEKSMKALRWDGGELREVTCCSDRRYDDAYTIKKVEQLQVQNFNFVAGMVPFLQNLIAMRQSGKQLVGKETFGICHALKELRDFMVVNGEPCKEKQKLLRNLRVIDLLVTLLKFPLKGTSDEHNLSRVFYYAYDILHTYMLGNSRKNALYFAKYIEFFQTQMIDKSDLALKVTKMLVELMKDNRKIVDRISKEQIDDFVDLLRKNEHYSYLELLKVLCVCNGVAITDNQSYIAQKWLLEDTRGIYLSERGQNIDRKPNETYVSTDQMKTWTPLVDFVQPDESDQESVERCLFLRTQLDLFIALCHGRNEECIRLITKDLSYLTWEEAYLGLSSDSLPQAFRAKYCEIVIGLFVNVGNNYSVVESPQLSFIYEYVGTKDSVGSATAPDQYAAKDLITVFPVIRDWITQFLDQNRFMVAAQIPNNMLIEQVLRLLHYLVKFGYYGDVHDLAMLLPPLKNLLNGENDVPFLPDKSSQGRADYTKDNKKIVQRFKQHDRYKKSPQTLAIVNAKHAALRVLDLVMTFQENARLASFISKFKDCEMSE-VKKKQARHPMVPALYSSFDSFDTKKSARKKQNAIRKELRIMFDESSRYLDTDNLTAILIDLANYEYDPMVELSLQLLNKLYSSKSSMFQRAINSLVLTTPDSCRVHREVSKQVPLLRMTARSKWTAEQARKMQTILGELYELCHLPKAEEEPHPMNQRLMISHNILPVIFDILATETDAQLSENYVETAGVLRKAVRLLKALTLRYPDVQEQVFAHLDDLLRVRLVESDLALALKEVFANNQELCLRVLPKQILRIVYLVAEHQERAPEFLELLSAIVKVEGTGLALKRNQTLVMKYIMQNYSRVAYILEQCSVKDRMDVLNGNRGADHCQYLVSFIDLLATCAEGENRYIESLCQTILSVQEILGILNDPDVENHLKKPFLRYMFFAYMKTTAAAGENRSLDIIHDSVTWQIWDYLDHLGRELLGLAYWIRDDADRDTVYFMTAKPFPKIMRLHDTCPLCSSLVSEDESKPLKLNLENAVVKMREDDYRGHSSLHYVFDAVFPFLQAFAQKFYVVDEDKDFQNEREIFDRMTTGAVEFCCQLASIVVEPKVLTQMVSCLSCIVKRSSHPPSIMEPVVENIGKGTKLQDTVSQMKSGNKEYYEQEIILNTKLKSLAVNLSLLWGGHNTVKAQLKVNSNREYTTIGGDEALPLDEEFQSHVRCLIGMGSRKPEQRYKLGALLVNGLRICATTSGTTHVPTTSTETKLRREQERLTVRILQILRAFMHNEERKLPADWEVRTTEFRVKKGLRNISDIQTTLNSFELVKHALPHLASTSSLVAKEVLSLLGMMLFNANERVQESMLNYFLHTKEEVFFYAVRNRLQMSTANIKERRLLISQQKARQSEAKSQAENLRATMTLGIKALQQIKQYRIEMKIEQANNDLTRRVSLTKMQSQSMMTKRRKESG--SQTPSNSSGKKSGGSGNKKVAF-----ANGLKGESQEPMAQSLLEESASSDSGAEVENLASQTHDEDETISMKDDGYIALVLKVLASICDGQHFGLQNYLREQPDNIKSFNIVAEVSQFINVAYSNINGDTIDLLIQLFSTVNEFCAGNQENRATVYDNKIIDYINFILRSSDFESCEPQQVVQLRQTIANLVISLIEENSPEALVIAREVKDTLDKGALYRAMSECYEAQQ----------------RTGKDGGFLVRLFKKEENRELKEAMYEVGFTFYVILARLYDIDPAMGKKDSD---------------PYGRELQISDIQQKAFKFFKKNAMTIEILKNDNLQKVHFRVRNKNVLREELKEKLKWNVDRSSPSTKIRDFMDWTKAILKDIHYQKKVLSNPFTILLTRLWLIWNHAATLTAVIINLIMLIGLEATDTPTMLADTGMF----TIP---ANESARWKSQFEHLEMWKDAFAYTMDILAIVILLAFFVANHPEPPNVRRIRDRLRRLRRAKADEEDDPA--DCRDRGSEGGNKLAVNLFSIATLYYLSFAACAFAGTFYCPYFFAFHLLNMVNNNQLLQGVIQAVTMNGLSLIWVSVLGIAIMYLFSVLAFARLRRGFGGL--MFCSDLSQCFVTVLRFGLIGDLFENMVPREDSPTFDSFFWMAIFHIVFFILITTVGLNIIFGIIVDTFSELRNMKWTAEVDMRDNCFICSRSNYDFEHHGQGFDYHVRNEHNMWAYIFFFIHLQDTAKNDYTSLELHVYKLLIEEKYDFFPMNRALCLSAKDEDSTESKIDELLQHVKNLVQHQKEEEAERKRWAELNRQRKWQRR 2726 HSP 2 Score: 102.064 bits (253), Expect = 2.994e-17 Identity = 40/65 (61.54%), Postives = 54/65 (83.08%), Query Frame = -3
Query: 8822 CIGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKY 9016
CIGD++ LYCE+TDG+VYS S+S+ FN L +YH DR+ P+ +PDPQ++ FQ+ IQNRYKL+KKY
Sbjct: 35 CIGDYVGLYCEDTDGHVYSHSSSNAFNGLFVYHSLDRDHPTQVPDPQVLLFQVCIQNRYKLDKKY 99
BLAST of SMED30029683 vs. TrEMBL
Match: A0A210PSZ2 (Inositol 1,4,5-trisphosphate receptor type 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13580 PE=4 SV=1) HSP 1 Score: 2427.9 bits (6291), Expect = 0.000e+0 Identity = 1286/2695 (47.72%), Postives = 1783/2695 (66.16%), Query Frame = -3
Query: 971 ITFQISIQNRYKLNKKYLRKFANIED-ENVLDADT-----RQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILVKESRDPRTVFKLHPVIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLT-EKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKI-SSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMK-NAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHD-----NNDSNKLLGAEAE------ELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIA------------NEVKDTLDKEAIYRVMTEAYEMHESESLTPDGI---RPKSNTN--------KSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENF-NISKYNNS---LPD-------------FFRNPVPDWKP-RFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGL 8872
+ FQI IQNRYKLNKKY RK+ N ++ EN ++ L QA+ AAEAEN DN AEQ R K+VRYGEV+QLK +F+ K++H++TTQTSQKDKNNM VSL+ N K AQF+ILPRYKVKSEGE VQ++DQI+ ES+KS GH+FHAS F +D+F GSELNLGVE+S FT++ Y + E FVRGG ++LFHKE+EAY+VAEGLFDDC+TE VH R+R IDQ ++L S S ITYWQIE E SI+ GD + W+QQ R RH TR YL +D + +V L ++ DPRTVF+LH V+++ +E+ FESYARIEH+L+G WLHALKD++Y R+ ERSM +RWD +RKV + YDDAYTIQ+V FNF+AG+VPFL NL++D L+AK+ + + +A +E+K FM+ G K RQKL+RNLRVID+LV LL L +E++ +++ E YD+L+ YMIG SRKNALYFAKYI+ F+TQ K I L V Q+IVELIRD RKIVDRI+K I+ F++ L N NYR+L+LL+VLCVC+GV I +NQ+YI ++WL + + VY+ +RGQNI+++PNI+YVSTD KSW+ L+ F+ + P + ++ +FLL QLDLF A+C+GRN++ +IT++ YL+WE+ +L + +E LPD +RAKYCE+IIGLFVDVGNNYSV+DHP FVYEYVG+KD QY DLVTIFP LRDW+A FL +N M AS I HN+LIEQVLRLL LVKFGYY D+DDV+ LL L+ L+DG+ D+PFP ++ GK +KE +K+V +Y+ R+ SKE AI+NAKY A+EVL +L F+ N RL F+ KFK+CE+N G +L +YE FNP+++ VR QK ++KEL+EM +++ I+ T++L +L+ Y Y KM +L++LN LYS + D FQ A+++ +L+T DS VHREV + +P+LR +AK K +DEQV I EL FCHLPK EEPH MNQ IL S V+ +++ILS E D++L ++Y + + +K L LL + + +Q +F +LD LL V++V S LA+ LKE+F+ NQ CLK+ +QI KIV LAA++Q +APEFL+LL +VKVEGL L +KRNQ LVMKYIMQ++ AAY+L+QP ++RE +L + H+ Y I L++LLSTCAEGEN++IESLCQTI+ VE+IL VLNH +I +LK+PF+KY+++ YLK N ES A++ +K++W F+ + + I L+ I + + V LL +P P K +A+ + H + Y+ ++V+ F+ ++ + D + E D + L + + + C +T P H+KA+ A +T +I ST ++ V+E ++ DT + +++GN EYY E+++N K TFA N ++I+ G+NTV AQ+K S R+YT ++ L LG+EFQ+ +KCFI + +K ++ A +L+ QL IS + G LA T E+LDI+C+Q+LRA+IHNEERKLPEDW T TS+ +IKK L I+++QN LN F K+LPH+A SD IA+EVL+ ++MLFNAN +QKS+LD+FL T+EEVFF AVR+R+Q+S +IKE+R LLAQ +R KEA + ++T+G +A++ I+ QR+K + S S+ ++ +K + K K + +F++S + N HD +N LL + E+ + +V E + + + + + KDDGYIELVLKLLAR+CDGQH GLQ Y+REQPDNVKSFN+V E QFLNVVY+ IN TIDL+ QVFST+NEF +GNQENR +YD K++DYIN+ILR G DC ++++L+Q I +LVI++IEEN P +Q+A EVKDTLDK A+YR MT+ +EMH+++ D + P +TN +F +I K E +K L EVGF++Y ILAR+ D+DP + ++ + I+P Q++AF FYKKNS+SIE++K + LQKV+FR++NKN +R+EVKE +KWNVDR+SPSNKIRD M W++ I+ DI YQ++ ++NPIA FT GWLLWNY T LSV +NL+ML + + + +E++ +++Y ++ LPD F++PVP + M+A G HN+ F+L +YFL++HPS P + +++ + E D+ Q+ +EG K+ S TFYY LG S+ G + YFFAFHL+NIV+NNQLL GVI AVTQNG SL+WVAILGM+VIY+YA++GFA R F LYC +LW C ++VMR+GL+GD+FE + D SF F LV+YH+SFFI ITTIGLNIIFGIIVDTFSELRDLKW ESDM+DTCFICSRNSYDFEH G+GF++HV NEHNMW+Y+FF IHL D K +DYT+++++V L++E+ +DFFP+NRALCL+ D DST+SKIDELL+ V+T+ N QK E++++KR E L+QKRWQ++HR F+ + + E D + LG+
Sbjct: 34 VVFQICIQNRYKLNKKY-RKWQNTDNRENSSSTESPAVAKHSLALQARLAAEAENKDNEAEQTRQYGKRVRYGEVVQLKHIFTGKFVHMSTTQTSQKDKNNMKVSLHEFNAKNAQFRILPRYKVKSEGEVVQLFDQIVFESVKSHGHYFHASESFQIDHFTFGSELNLGVERSSFTLIGCYREHADQERFVRGGSVIRLFHKELEAYLVAEGLFDDCITEDVHFRVRVIDQHRPKSLSASTSGITYWQIEAEHSILDGDVIRWEQQIRMRHLLTRQYLCIDSKMDVSLANDASDPRTVFRLHSVLKERDEIQFESYARIEHMLTGCWLHALKDEDYDRRGMEEN-GERSMQGLRWDTASVRKVSASSESMYDDAYTIQEVVRLDTSNFNFVAGMVPFLFNLIQDLQLATQLNAKKTHGIIVALQELKNFMVPQGLPDKNRQKLMRNLRVIDILVNLLQCCLREGDEESHMIRIFKEAYDVLHAYMIGKSRKNALYFAKYIDFFQTQFTQKGGIGLNVAQMIVELIRDKRKIVDRITKKHIDTFIQLLIKNHNYRFLDLLQVLCVCDGVAIPNNQSYIVEQWLRKYKASVYMMDRGQNINKRPNIVYVSTDGAKSWVPLNVFVDTEGPEFVEDDYKFLLHQLDLFKALCFGRNDFSGFVITREYGYLTWEDAYLCMTAEQLPDIIRAKYCELIIGLFVDVGNNYSVLDHPNICFVYEYVGSKDAK--VEHSQYVVMDLVTIFPVLRDWLAEFLRQNCQMTASDIGHNLLIEQVLRLLQHLVKFGYYLDIDDVKQLLTPLLSLLDGTHDVPFPKDK-GKGYTKESQKLVTQYRSKGRFDSSKENEAIINAKYRAMEVLDFLLTFQRNLRLKAFVTKFKQCEQNLG------HRTLEPLMYESFNPHDQSKKVVRHQKQVLKELKEMVGSSSIFDIESTTSVLKDLSMYSYDKMVTKSLDILNKLYSSQSDMFQLASKAQILLTHDSAKVHREVQRSLPVLRRLAKQKLNDEQVTLTGEILDELAGFCHLPKNLEEPHFMNQNILVSHGVLPAILDILSQEIDAKLVDQQYKGMKTIFKKTLDLLALITRENSAMQEAMFNHLDTLLEVQIVPSCLALALKELFIANQTTCLKVHSKQIQKIVLLAAQYQSEAPEFLELLKVLVKVEGLDLTIKRNQALVMKYIMQNFRKAAYVLDQPRDSREQILTNKRDPGHLAYFICLVDLLSTCAEGENKFIESLCQTIMPVEEILWVLNHRDIDGNLKQPFVKYMLWVYLKPAGNLVESGAADLQHDKEMWNFVASAADTIKQLSDTITKH-RDRVALLLKQP---------------------PGK-------SAVAVPGDTNAGLHGCVFYVLEAVLPFVEVFYSMFYSPDKDLYPGEIDTTETLAQGLSSFCEVAGQFLTSPVHMKAIAASITILISVSTTNKSLYISVLERFSTEMRLGDTKSAVRKGNMEYYAGELELNAKFHTFAKNNNIIYQGYNTVAAQIKYKKSKREYTAQGTNEELLLGEEFQSLVKCFIDVHERKPAKRFLPARILLEQLQISQESIRQG-LAQT----------EELDIKCMQILRAIIHNEERKLPEDWDTCTSDQKIKKQLAYIKEVQNALNVHGFVEKVLPHVARRSDLIAREVLAFMSLMLFNANRDVQKSMLDFFLSTREEVFFMAVRDRMQISTNSIKEKRSLLAQHQARVKEAFNNMGSFNASLTVGRKALQLIQDY--EQRLKEEKMQGWSALSRAKEPP-HDQKRRSKKRKSKQQESFKKSKKLGVIPNGLAHDHTVIRDNSHEALLKPAPDSPDFTPEVELTSVNVESMKTAENMVSNIDEGVVDMLEYKDDGYIELVLKLLARLCDGQHCGLQNYMREQPDNVKSFNIVGETAQFLNVVYSTINSKTIDLIIQVFSTLNEFCSGNQENRFVIYDRKVVDYINFILRAGELADCDPEKILDLRQAIASLVIALIEENGPGKSQVAKQGKADELRYIHKEVKDTLDKNALYRCMTQCFEMHQADKPKLDDVLNNGPPGSTNYLKSAKSIAAFGGNFISGVMSGKKENASMKEMLMEVGFTFYLILARMIDIDPAMPERVD-----------------------ISPEQRRAFDFYKKNSMSIEIVKDNILQKVNFRVKNKNYLRDEVKEKLKWNVDRTSPSNKIRDLMSWTRDIMKDISYQRRILHNPIAMLFTKGWLLWNYGATFLSVAINLLMLLTW---NNKATEEDYAKLAEYGSTHAPLPDGSPGSTLSPPNWEVFKDPVPRISGISLDTYTILMYALGGTHNLFSLFVLISYFLSNHPSLPTCKEITDVVRGVFGKKE--KVDDSGDQKKEEGSKLEVKFFSFTTFYYVFFLGMSVMGTLFHGYFFAFHLLNIVNNNQLLSGVIKAVTQNGVSLLWVAILGMIVIYIYALVGFALLREFFTPGDYLYCTNLWQCTITVMRYGLIGDMFETIHQTDLRNSFEYFWPLVLYHVSFFIFITTIGLNIIFGIIVDTFSELRDLKWRTESDMKDTCFICSRNSYDFEHTGKGFDHHVRNEHNMWAYVFFLIHLDDVKTSDYTAMELYVNKLMEEENYDFFPMNRALCLSTVDVDSTESKIDELLQQVTTIANKQKQEEADKKRKVEKLKQKRWQEKHRQFMFGISTEDIHREGDTDTLLGV 2646
BLAST of SMED30029683 vs. TrEMBL
Match: A0A1S3H9B8 (inositol 1,4,5-trisphosphate receptor type 3 isoform X13 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1) HSP 1 Score: 2422.12 bits (6276), Expect = 0.000e+0 Identity = 1277/2751 (46.42%), Postives = 1787/2751 (64.96%), Query Frame = -3
Query: 968 CIGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILVKESRDPRTVFKLHPVIQDSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGT-----KDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPAT--------------------------IMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQR----MKNA-VNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRL----HDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNK-------SFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKR---RLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN------------------EGSLEKLDEDDNENGLGLR 9016
CIGD+I L+CEET+GYVYS TSS N L IY QDR +P IP+P ITF++ IQNRYKLNKKY RK ++ + + + L QAK +A AEN DN++EQ+R K+VRYGE+IQLK VF+DKY+H++TTQTS +DKNNM++SL+ +N K AQF+ILPRYKVKSEGEYVQI DQI+ ES KS GH+FH+S+P+ ++ ++GSELNLGV Q+GFT+V+ Y DE+E VRG F++LFHKE+EAY+VAEGLF + V E+VHLRIREIDQLN RTL NSAITYWQ+E E +I++G + W+QQ R RH TTR +L +D + V L E DPR+VF+ HPV+ + E+ FESY RIEHVL+GNWLHALKD+ Y+R++ E++RSM A+RWDGGE+RK+ +RRY D +TI +V E NF+AG+VPFL L+E R + +L+A + +++ A +E+K+FM++NG++ K QKL+RN R++DLLV+LL PL PD L V E YDILYTYM G+SRKNALYFAKYIE F+TQ+ K +I L V Q++VELIRDNR+IVDRI+ QI+ FV+ LR +NYR+L+LL VLCVC+G I++NQ+YI + WL D+ VYL ERGQ IH++ N++Y+STD +W+ LH+F D P Y +E+ +L QLDL +C GRN++ IR+ITKDL L+WE F+ L+SE+LP +RAKYC +II LFVDVG ++SV+D FVYE + +++ T+ + A++L T+FP +RDWI F++ N M +S++ N LIEQV+RLL +LV+FG Y D++R LL L+ ++DG D PFP + + SKE KK+V++Y++ DR+ +S ET A+V+AKY L VL+++ F+SN RL F++KFK E KKK+ S L+ + + ++ + +RKQK + ELR MFE+++ ++ +TNI ++L++YKY KM +L +LN YS K D F+ A +LVL T +SC +H ++ +Q+PL+R +AK ++ EQ M +F + + F HL P HPMNQ+IL + V+ ++ ILS E D Q+TE+ + E V KAL LL+ +A DVQ ++ + LD L+ +KLV S LAI L+EVF NQN CLKI P+QI KIV LA E+Q +APEFLDLL +IVKVE L L LKRNQ LVMKY+MQ+Y AAY+ +Q E R +L + G H +YLISL++LL+ CAEGENRYIESLCQTI+ +E+I++VLN+ I N+LK P+L+YLM+ Y+K ES ++ ++ +W +I L E L YI E+ + V + P PK A+ + + + AHA++ Y FD+V+ FL + + + D E E + D L S+V C + + HLK +I CV ++ S++P +ME +E G G + D + + YY E ++N K + F+ NCSL++ GHNTV AQLK S R+YT + GD+ LPLG+EFQ H++CF+ N K +Y+ L+ QL +SA N + E ++LDI+ LQ+LRA+IHNEERKL EDW+ T + +++K LK I ++QNTLNS+ ++LPHL PS+ I +E L+ ++MLFNAN +Q+++LD F + E FF+A+R RL+++ +KERR L Q +R KE+ QAK+L T +T+G +AMK+I+ + ++R MK A NSL + RQ + + K + F+ +G E P + H++ + N+++ ++ L++ + E D + + KD+GYI LVL+LLA +CDGQ+ +Q YLR+QPDN+KS N+VA+ QF+NVVY+NI TIDLV Q+FST+NEF AGNQ NRV + DNK++DYIN+ILR G Y S+ +EL++ I NL++S+IEEN P+ ++A EVKDT+DKEA+YR M + Y +H+ P + K +TN S ++ + M K++ DLK K EVGF Y+ ++AR YD+DP L +K GL+ITP+Q A+ +YKKNS+SIEL+K LQKVHFR++NKN++REEVKE +KW+VDRSSPSNKIRD M WSK IL DI YQ+K + NPIA FFT WLLWNY + +LSV +N++ML +KAP D S N++ ++++ NP PD E ++A G HN+ F+L +YFL++HP P + L +R R + E + A E ++ K+ S TFYY +G S+AG ++ YFFAFHL+NIV+NNQ+LQGVI AVTQNG SL+WV ILG+++ Y+YA+I FAF R+ F + YC +L C V+V+R+GL+G +F+ L +SE +F F+++ ++HLSFFILITTIGLN+I GI+VDTFSELRDLKWTAESDMRDTCFICSR S+DFEHHG GF H EHNMW+YIFFFIHL DTK+NDYT+LD+ VA L+ ++++FFP+N AL LT +ED TD KID +L+ V+ L+ Q+ E+S+R R EE RQK+WQ+ +R LS EG + +DD+ G G+R
Sbjct: 6 CIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKY-RKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHSSVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSDENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSPPNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSEQNEIDFESYCRIEHVLTGNWLHALKDEPYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMKTHQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYLLSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKGDIGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANADSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRDWIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQN-SKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKTAETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHPMNQKILINHGVLDLIFAILSQEVDVQITEQAAPMELVFGKALNLLRFLAQGNEDVQAKMNDRLDSLMNIKLVPSHLAIALREVFAGNQNNCLKIQPKQILKIVHLAGENQDRAPEFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTMIESGAGDLPHDRHVWIYIQALAREAESLKTYISENEVKTVEVMRAPP---------------------PK--------GAVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYPSLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHKSKREYTEIGGDEDLPLGEEFQAHVRCFVKHNEKNIAKRYQNVSKLVQQLAVSANAVN---------PKDGTYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQRTMLDVFKSMRTETFFFAIRIRLEIAANGLKERRALATQHEARVKESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSISPASSKCNSLQR--FKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSV---------------DVEEDDVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKYEGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCYSIHQ-----PPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDPVLNEK---------------------AGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVLMLWAWKAPYDMSQAPE-NMTHLDHAI----YNPNPD-TSSVEIYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLCGRKDEEEDEIAHEVDCEKAKRQSKLDVKFFSLATFYYVIFVGMSVAGTFFHGYFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPESENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTG-EEDGTDEKIDAVLEKVTELLRRQREEESKRMREEEHRRQKQWQEMYRKALSGSHDTLAAAIEGPRRPEDREGDAARYSDDDDSRG-GVR 2665
BLAST of SMED30029683 vs. TrEMBL
Match: A0A1S3H6U8 (inositol 1,4,5-trisphosphate receptor type 3 isoform X12 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1) HSP 1 Score: 2414.42 bits (6256), Expect = 0.000e+0 Identity = 1284/2776 (46.25%), Postives = 1791/2776 (64.52%), Query Frame = -3
Query: 968 CIGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILVKESRDPRTVFKLHPVIQ-----------DSEEVTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDR--------------RGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGT-----KDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPAT--------------------------IMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQR----MKNA-VNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRL----HDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNK-------SFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKR---RLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN------------------EGSLEKLDEDDNENGLGLR 9016
CIGD+I L+CEET+GYVYS TSS N L IY QDR +P IP+P ITF++ IQNRYKLNKKY RK ++ + + + L QAK +A AEN DN++EQ+R K+VRYGE+IQLK VF+DKY+H++TTQTS +DKNNM++SL+ +N K AQF+ILPRYKVKSEGEYVQI DQI+ ES KS GH+FH+S+P+ ++ ++GSELNLGV Q+GFT+V+ Y DE+E VRG F++LFHKE+EAY+VAEGLF + V E+VHLRIREIDQLN RTL NSAITYWQ+E E +I++G + W+QQ R RH TTR +L +D + V L E DPR+VF+ HPV+ + E+ FESY RIEHVL+GNWLHALKD+ Y+R++ E++RSM A+RWDGGE+RK+ +RRY D +TI +V E NF+AG+VPFL L+E R + +L+A + +++ A +E+K+FM++NG++ K QKL+RN R++DLLV+LL PL PD L V E YDILYTYM G+SRKNALYFAKYIE F+TQ+ K +I L V Q++VELIRDNR+IVDRI+ QI+ FV+ LR +NYR+L+LL VLCVC+G I++NQ+YI + WL D+ VYL ERGQ IH++ N++Y+STD +W+ LH+F D P Y +E+ +L QLDL +C GRN++ IR+ITKDL L+WE F+ L+SE+LP +RAKYC +II LFVDVG ++SV+D FVYE + +++ T+ + A++L T+FP +RDWI F++ N M +S++ N LIEQV+RLL +LV+FG Y D++R LL L+ ++DG D PFP + + SKE KK+V++Y++ DR+ +S ET A+V+AKY L VL+++ F+SN RL F++KFK E KKK+ S L+ + + ++ + +RKQK + ELR MFE+++ ++ +TNI ++L++YKY KM +L +LN YS K D F+ A +LVL T +SC +H ++ +Q+PL+R +AK ++ EQ M +F + + F HL P HPMNQ+IL + V+ ++ ILS E D Q+TE+ + E V KAL LL+ +A DVQ ++ + LD L+ +KLV S LAI L+EVF NQN CLKI P+QI KIV LA E+Q +APEFLDLL +IVKVE L L LKRNQ LVMKY+MQ+Y AAY+ +Q E R +L + G H +YLISL++LL+ CAEGENRYIESLCQTI+ +E+I++VLN+ I N+LK P+L+YLM+ Y+K ES ++ ++ +W +I L E L YI E+ + V + P PK A+ + + + AHA++ Y FD+V+ FL + + + D E E + D L S+V C + + HLK +I CV ++ S++P +ME +E G G + D + + YY E ++N K + F+ NCSL++ GHNTV AQLK S R+YT + GD+ LPLG+EFQ H++CF+ N K +Y+ L+ QL +SA N + E ++LDI+ LQ+LRA+IHNEERKL EDW+ T + +++K LK I ++QNTLNS+ ++LPHL PS+ I +E L+ ++MLFNAN +QK++L+YF+ TK+E FF+A+R RLQLS IKERR L Q +R KE+ QAK+L T +T+G +AMK+I+ + ++R MK A NSL + RQ + + K + F+ +G E P + H++ + N+++ ++ L++ + E D + + KD+GYI LVL+LLA +CDGQ+ +Q YLR+QPDN+KS N+VA+ QF+NVVY+NI TIDLV Q+FST+NEF AGNQ NRV + DNK++DYIN+ILR G Y S+ +EL++ I NL++S+IEEN P+ ++A EVKDT+DKEA+YR M + Y +H+ P + K +TN S ++ + M K++ DLK K EVGF Y+ ++AR YD+DP L +K GL+ITP+Q A+ +YKKNS+SIEL+K LQKVHFR++NKN++REEVKE +KW+VDRSSPSNKIRD M WSK IL DI YQ+K + NPIA FFT WLLWNY + +LSV +N++ML +KAP D S N++ ++++ NP PD E ++A G HN+ F+L +YFL++HP P + L +R R + E + A E ++ K+ S TFYY +G S+AG ++ YFFAFHL+NIV+NNQ+LQGVI AVTQNG SL+WV ILG+++ Y+YA+I FAF R+ F + YC +L C V+V+R+GL+G +F+ L +SE +F F+++ ++HLSFFILITTIGLN+I GI+VDTFSELRDLKWTAESDMRDTCFICSR S+DFEHHG GF H EHNMW+YIFFFIHL DTK+NDYT+LD+ VA L+ ++++FFP+N AL LT +ED TD KID +L+ V+ L+ Q+ E+S+R R EE RQK+WQ+ +R LS EG + +DD+ G G+R
Sbjct: 6 CIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKY-RKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHSSVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSDENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSPPNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSLREQDLDPDTPEQNEIDFESYCRIEHVLTGNWLHALKDEPYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMKTHQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYLLSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKGDIGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKVSFDAKTCHIHLTGADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANADSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRDWIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQN-SKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKTAETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHPMNQKILINHGVLDLIFAILSQEVDVQITEQAAPMELVFGKALNLLRFLAQGNEDVQAKMNDRLDSLMNIKLVPSHLAIALREVFAGNQNNCLKIQPKQILKIVHLAGENQDRAPEFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTMIESGAGDLPHDRHVWIYIQALAREAESLKTYISENEVKTVEVMRAPP---------------------PK--------GAVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYPSLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHKSKREYTEIGGDEDLPLGEEFQAHVRCFVKHNEKNIAKRYQNVSKLVQQLAVSANAVN---------PKDGTYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQKAMLEYFMSTKKESFFFAIRCRLQLSAIAIKERRALATQHEARVKESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSISPASSKCNSLQR--FKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSV---------------DVEEDDVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKYEGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCYSIHQ-----PPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDPVLNEK---------------------AGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVLMLWAWKAPYDMSQAPE-NMTHLDHAI----YNPNPD-TSSVEIYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLCGRKDEEEDEIAHEVDCEKAKRQSKLDVKFFSLATFYYVIFVGMSVAGTFFHGYFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPESENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTG-EEDGTDEKIDAVLEKVTELLRRQREEESKRMREEEHRRQKQWQEMYRKALSGSHDTLAAAIEGPRRPEDREGDAARYSDDDDSRG-GVR 2690
BLAST of SMED30029683 vs. Ensembl Cavefish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3]) HSP 1 Score: 184.882 bits (468), Expect = 9.278e-46 Identity = 140/535 (26.17%), Postives = 242/535 (45.23%), Query Frame = -3
Query: 1013 EVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLK-----QNELDPADE-DIIQQ--------GDEGCKMRSH--LISSKTFY----YFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLY-------------------------CDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSL 2467
E K V ++ +R +KI DF + + N++R+QKK P+ + + W+ L+V++N+ L F P D D S +L W+ G + GF++ PSP ++ I RL Q+ L ++ + G+ G R + ++ + F Y I L G + F++ L ++V+ + L VI +VT+NG+S++ A+LG++++YL++I+G+ FF+ F E N CDSLW C ++V+ GL VGD+ P E F+ VIY L FF L+ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W Y++F + ++ + +YT + +VA ++KE D+FP RA+ L + D + +++ L + + + + + ++ +E + ++R K+ G L N L
Sbjct: 2131 ESKLRVYYSTERDEQGSKINDFFLRADDLYNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINV--LVAFFYPLDSVRDSTLEPSL---------------------SLLLWVCVLGSL-----GFVVLL------PSPNAVRILVISSVLRLGFSLGLQHMLSLLGAFNVCNKIVFLLSFVGNRGTFTRGYRAMVMDREFLFHLLYLLICTLGLCGHVF---FYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYIFFKDDFILEVNRIPNRNINVCVFGMLCPFVCADDVERACDSLWMCMITVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLYFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRCLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRIGLLGNPAHL 2623 HSP 2 Score: 150.599 bits (379), Expect = 2.132e-35 Identity = 222/926 (23.97%), Postives = 378/926 (40.82%), Query Frame = -3
Query: 6515 IGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQP--SHIPDPQM----ITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAV------DEES---------------------------NVILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFM------------LVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPD-------------EANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVS--TDCMKSWI------------ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPER-----SFVYEYVGTKD-QNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE---NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVR 9013
IGD LY E STS F + L + + QP + +P F++ NRY K++ K A + D L ++ AA+ E N +E ++ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D E ++GG V+LFH E E ++ DD +Q ++ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA +EE ++ V + D ++F+L P + V SY R+ H+ + W+H+ K E+E+ + +R L++ D+ +A+ I V P R +F L + + +L++ + E V ++ F+ + K + RQKL+R ++ + KLL P D A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV I Q I +L+ G L E + N ++ D + W+ ++ + Q G+ D E + + QL+LF +C R I I+ L + + E LP D+RA +C M++ + VD V P + S + + D N T+ D+ K F +++ +L + ++ + K E N L +V+ L L+ FG+Y D +R
Sbjct: 11 IGDICSLYAEG--------STSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFW-KAAKPGGTSTTDT---VLLNKLHHAADLEKKQNESENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASGHQLVDN-PGCNEVNSVNCSTSWKIVLFMKWSDNQEVVLKGGDVVRLFHAEQEKFLTC----DDHRKKQ-YVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSVSVCLLYTQLWKKLRDHFIMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNHPIDK-------EEEKPV-MLRIGTSPLKE-----DK---EAFAIVPVSPAEVRDLDFANDASKVLAS-IAGKLEKGTITQNERRAVTKLLEDLVYFVVDIPNSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNA-VLDPANGDILIETKYDKICATNHCRLTDREDEEEVWLFWKDSSGEVKSKSIRELAQDAKDGHTEDQEVISYYRYQLNLFARMCLDRQYLAINKISAQLDV---DLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVT--PVKYARLWSEIPSQISIDDYDNDGTSRDEVKEK-----FSQTMEFVENYLRDVVCQSFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLR 880 HSP 3 Score: 79.7221 bits (195), Expect = 6.071e-14 Identity = 120/560 (21.43%), Postives = 227/560 (40.54%), Query Frame = -3
Query: 4916 KETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKE--CERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMA--------KSKWSDEQVNRMENIFSE----------------------------------LIEFCHLP-KAPEEPHPMNQRILDSDNVIGVVMEILSV--ETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAV----LKEELGEDH--VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFI-----------GNLGEEIH---YLTQYILESPHELVYYLLTKPF 6373
K+ +++ K +E+LQ ILN + R++ ++ FK E N + NP S AL F E++ + E T + +D +L++L + Y + AL +L +S +Q+ QA + +L+T+ ++++ + LR + K + SD ++ E I SE L + C + + + QR+L + VV+E+L + E D + E + + L+ + QNQ + +++++ L ++E A+T++ +F+NN LC +I R + V H ++ +L L IVK E +K+ Q +VM ++ + + V L+ E +D+ ++Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N + H L +Y+ E+ +V + PF
Sbjct: 952 KQDILVMDTKLKIIEILQFILNVRLDYRISCLLSIFKREFDESNSQVEPSINPDSHTSAL--DFEHIEEQAEGIFGGS----------EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKADLDQLRSIVEKSELWVYKRQGSDSGLHTGEGIASETHHKSDSISDGMDKPKVESTSSSNYRLMKEILLRLSKLCVMECLSGRKNKKQQQRLLRNMGAHSVVLELLQIPYEKDVWMQEIMTLAHQFLQNFCA---------GNQQNQTLLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINERVVQHFVHCIETHG-RSVHYLKFLQTIVKAENK--FIKKCQDIVMAELVNAGEDVLVFYNDRASFQTLVQMMRLERERLDDNSALRYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYV-----DTEVEMKEIYTSNHMWKLFDDFLVDICRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPF 1479
BLAST of SMED30029683 vs. Ensembl Cavefish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]) HSP 1 Score: 172.94 bits (437), Expect = 3.198e-42 Identity = 134/540 (24.81%), Postives = 240/540 (44.44%), Query Frame = -3
Query: 1028 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAP----KDGSFDENFNISKYNN---SLPDFFRNPVPDWKPRF--ENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-----------------------------------NTE--------KNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLS 2476
+ +E K V + +R +KI DF S+ + N++ +QKK PI + + W+ L+V++NL L F P + G+ D + + + SL P P + +F+ GL + FLL + + + ++ + + R G ++ ++ + Y+ L G + +F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+G+ FF+ F TE K CDSL C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+FF + ++ + +YT + +VA +++E D+FP RA+ L + D + ++I L + + + + + + +E + ++R QK+ G L
Sbjct: 2185 LTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNL--LVAFFYPLGGIRGGTLDPHLSALLWVAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTL---FLLGAFNVCN-----KVIFLMSFVGNR----------------GTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILAVDRIPNKTMMSEFLTGGVCRKEGGGENCSSEVTTETVAMVVEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLIKVKDSTEYTGPESYVAEMIREHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLVSNLSGQLTELKEQMTEQRKQKQRIGLLG 2693 HSP 2 Score: 148.288 bits (373), Expect = 9.436e-35 Identity = 202/824 (24.51%), Postives = 337/824 (40.90%), Query Frame = -3
Query: 6797 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLA-----------------VDEES----------------NVILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQF------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPL-------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCV-------------CNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYV-------STDCMKSWIALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVD 9013
IGD LY E T+G++ ST ++ + N P D F++ NRY K++ K A + D L ++ AA+ E N +E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D E ++GG V+LFH E E ++ DD +Q ++ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA +D E ++ V + D ++F+L P + V SY R+ H+ + W+H+ DKE ++ + ED+ + + E+R +D +DA + F+ LLED + F + + +++ E M+ K + RQKL+R ++ + KLL P G A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV CN V N + + L+ R + G+ E ST ++S ++ + Q G D E V + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPDTGDLNNPPKKFRD---CLFKLCPMNRYSAQKQFW-KAAKPGGNSTTDT---VLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASTHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWSDNKEVILKGGDVVRLFHAEQEKFLTC----DDHRKKQ-YVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEESHESRSSLDSEHEALRARLRTPNEKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDKEEEKPVMLRIGTSAIKEDKEAFAIVPVPPAEVRDLDFA-----NDASKVLASIAGKLEKGTITQNERRFVTKLLEDLV---FF----VVDIPNSGQDVLEIMV--NKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEIEAVNVGEPPVEAEEDEEEVWLFWKDSTKEIRSK-SIRELAQDAKEGQKEDQEVVSYYRYQLNLFARMCLDRQYLAINKISGQLDV---DLILRCMSDEDLPYDLRASFCRLMLHMHVD 791 HSP 3 Score: 70.4774 bits (171), Expect = 3.863e-11 Identity = 66/259 (25.48%), Postives = 117/259 (45.17%), Query Frame = -3
Query: 4916 QNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPF 5617
QNQ + +++++ L ++E AIT++ +F+NN LC +I R + V H + ++L L IVK E +K+ Q +VM ++ + Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L +Y+ E+ +V + PF
Sbjct: 1254 QNQALLHKHINLFLNPGILE---AITMQHIFMNNFQLCSEINERVVQHFVHCIETHGRHV-QYLKFLQTIVKAENK--FIKKCQDIVMAELVNAGEDVLVFYNDRASFQTLVQMMRSERDRMDEN---SPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYIDFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRVCNNTSDRKHADATLERYVTETVMSIVTTFFSSPF 1498
BLAST of SMED30029683 vs. Ensembl Cavefish
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192]) HSP 1 Score: 168.703 bits (426), Expect = 6.253e-41 Identity = 220/914 (24.07%), Postives = 385/914 (42.12%), Query Frame = -3
Query: 6482 IGDFICLYCEET-DGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILVKESR----------------DPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQQF------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFM-LVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDE-------------ANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYL-------TERGQN---IHEQPNILYVSTDCMKSWIALHK--------FLQVDYPG---YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID 9013
IGD + LY E T +G++ ST ++ + + N P D F++ NRY K++ + + N + D L + + AAE E N E ++ + V+Y +VIQL + S+KY+ VN + +KN M VSL+P ++ + F I P +K++SEG+ V + D+++L + + G HAS LDN +E+N + + + D + ++GG V+LFH E E ++ + D Q H+ +R + +A T TS+ A+ W++E G W+ FRF+H T YLA + ES+ + K+ R D ++F+L + V SY R+ ++ + W+ + D E +R T ED+ + + E+R +D +DA + + + F F+ LLED + + VC ++ + +V + RQKL+R ++ + +L P + D A F + CY IL + RKN Y AK + ++Q+ + I L+ +NRK++++ I+ +I FV+ LR N R+L+ L LCV N I Q I + L + + TE + +HE+ + + WI +K L D G D + + + QL+LF +C R I I+ L + + + LP ++RA +C +++ + VD +VV P R Y + + +K + + + D+ F D++ +L + + E N L +V+ L LV FG+Y ++ L L+ ++D
Sbjct: 11 IGDIVSLYAEGTVNGFI---STLGLVDDRCVVQPEAGDLANPPKKFRD---CLFKVCPMNRYSAQKQFWKAKQGKQGGNT-EGD---LFKKLQHAAELEQKQNETENKKLLGEVVKYSQVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDPSGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDN-PGCNEVNAVNCNTSWKVTLFMKFSDYKDDILKGGDVVRLFHAEQEKFLTCDDYKD-----QQHIFLRTTLRQSA-TSATSSKAL--WEVEVVHYDPCRGGAGQWNSLFRFKHLATGKYLAAETESDAVYSKKKRPVEKITYILVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRNLCTNTWVTSTNNSIDHEEERPVMLKIGTCPTKEDKEAFAIVSVPLSEVRDLDFA-----NDANKVLEAFVRKLEKNTFAQNDRRFVIKLLEDLV----------FFVCEVPNNGQDVLSVVISNPNRERQKLMREQNILAQIFGILKAPFADREDGPILKLEDLGDQRYAPFKYMLQLCYRIL-RHSQQDYRKNQEYIAKKFSIMQSQI----GYEILAEDTITALLHNNRKLLEKHITAREIETFVKLLRRNREPRFLDYLSDLCVSNKTAIPVTQELICKFMLNPTNADILIQTKLIPHTENSMDSSLMHEEGD----EEEVWLYWIDHNKEPHGKSIRHLAQDSKGNHKLDIDIITYYRCQLNLFAKMCLDRQYLAINQISTQLPV---DLILRCMFDDCLPYNLRASFCRLMLHMHVDRDPQEAVV--PVR---YARLWNEIPSKISVKEDTSRADMKRKFAPTMDFVDEYLKDVLSQPFPFGDEEKNELTLEVVNLARNLVYFGFYS-FSELLCLTRTLLAILD 871 HSP 2 Score: 150.214 bits (378), Expect = 2.850e-35 Identity = 88/304 (28.95%), Postives = 161/304 (52.96%), Query Frame = -3
Query: 1025 LAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLY--------------------CDSLWHCFVSVMRFGLV-GDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 1873
+ G + +F++ L ++V + L V+ +VT+NG+S+ A+L ++++YL++I+GF F +S F E + + C++L C V+V+ GL G ++L S K F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y++F + ++ +YT + +VA ++KE+ D+FP +A+ L +S +++ L + + + ++ +E + ++R K+ GFL +
Sbjct: 2233 MLGLFVHEFFYSILLFDLVRREETLLNVMRSVTKNGRSIFLTAVLAIILVYLFSIVGFLFLQSDFLMEVDRHPALDLTCKVEKSDEPEMERVCETLLMCIVTVLNHGLRNGGGIADILRKPS-KDEPMFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVSFEEHIKVEHNMWHYLYFLVLVRVKDPTEYTGPESYVAQMIKEKNLDWFPRMQAMSLVTSAGESEQNEMRSLQEKLDITVTLVSQLSAQLAELKEQMTEQRKNKQRMGFLGS 2535 HSP 3 Score: 67.781 bits (164), Expect = 2.532e-10 Identity = 62/215 (28.84%), Postives = 105/215 (48.84%), Query Frame = -3
Query: 5009 QNQIF--ENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDH-VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQF 5617
QNQI ++L++ L ++E A T+ +F NN +LC +I R +H V H ++ +L L IVK +G +K+ Q VM ++ Y+ A L Q M + +E E+ + Y I+L+ELL+ C EG+N Y E C ++L ++DI+NV+ H + +K ++ ++ Y+ +E EI IW+
Sbjct: 1216 QNQILLHKHLNLFLTPGILE---ARTMHYIFQNNYHLCNEISDRVVHHFVHCIETHG-RSIHYLRFLQTIVKSDGK--YVKKCQDKVMTELVNGGEEVLLFYNDRASFPALLQLMNSE----RERHDENSALSYHINLVELLAACTEGKNVYTEIKCNSLLPLDDIVNVVTHDDCIPEVKIAYVNFVNHCYV-----DTEVEMKEIYTSNHIWKL 1415
BLAST of SMED30029683 vs. Ensembl Cavefish
Match: ryr1b (ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:ZDB-GENE-070705-417]) HSP 1 Score: 149.828 bits (377), Expect = 4.506e-35 Identity = 91/261 (34.87%), Postives = 138/261 (52.87%), Query Frame = -3
Query: 1172 LISSKTFYYFA-ILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNT-----EKNLYCDS-----LWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDED 1921
+ + TF Y L SL G Y+ +FFA HL++I + L+ ++S+VT NGK L+ L VV+YLY ++ F FFR +N E ++ CD L+H +V V G +GD E+ P E + V++ ++FF + I L II G+I+D F ELRD + DM CFIC S F+ GFE H L EHN+ +Y+FF ++L + ++T + +V + +E+ +DFFP C + ED
Sbjct: 4703 VFTDNTFLYLVWYLVMSLLGH-YNNFFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNMSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIED--PAGDEYELYR----VVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGD--CFRKQYED 4954 HSP 2 Score: 82.8037 bits (203), Expect = 8.341e-15 Identity = 84/313 (26.84%), Postives = 133/313 (42.49%), Query Frame = -3
Query: 7877 AENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQ---FKILPRYKVKSEGEYVQIYDQIILESIKSPG--HFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAI-----TYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILV--------------KESRDPRTVFKLHPV-IQDSEEVTF-ESYARIEHVLSGNWL-HALKDKEYKR 8734
A VD + ++ + YG I L+ S Y+ TT S DK + V L D T + + I P K +SEGE V++ D +IL S+ S H AS +D M + N+ SG + +E F+ GG ++LFH M D+C L I DQ + + + A+ + W++E + SG + W Q FR RH +T Y+ +DEE ++++ + S++ V K V E+ + ES ++HV +G WL +A D + R
Sbjct: 66 ANTVDLSESSQGGAHRTLLYGHAILLRHNHSSMYLSCLTTSRSLTDKLAIDVGL--QEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSMASGDLMVDASFMQTLWNMNPVCSGCEL---------AEGFLTGGHVLRLFHGHM----------DEC------LAISPPDQGEDQIAQYESGAVCSQARSLWRLEPLRISWSGGHMKWGQAFRIRHISTGRYVCLDEEKGLMVLDPEKANTKLSAFCFRASKEKVEVAKKRDVEGMGIPEIKYGESMCFVQHVSTGLWLTYAALDAKAAR 351
BLAST of SMED30029683 vs. Ensembl Cavefish
Match: ryr1a (ryanodine receptor 1a (skeletal) [Source:ZFIN;Acc:ZDB-GENE-020108-2]) HSP 1 Score: 149.058 bits (375), Expect = 7.384e-35 Identity = 87/248 (35.08%), Postives = 134/248 (54.03%), Query Frame = -3
Query: 1211 LISSKTFYYFA-ILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFN-----TEKNLYCDS-----LWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFP 1921
+ + TF Y SL G Y+ +FFA HL++I + L+ ++S+VT NGK L+ L VV+YLY ++ F FFR +N E ++ CD L+H +V V G +GD E+ P E + V++ ++FF + I L II G+I+D F ELRD + + DM CFIC S F+ GFE H L EHN+ +Y+FF ++L + ++T + +V + +E+ +DFFP
Sbjct: 4683 VFTDNTFLYLVWYTVMSLLGH-YNNFFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDENEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIED--PAGDEYELYR----VVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4923 HSP 2 Score: 80.8777 bits (198), Expect = 3.240e-14 Identity = 70/236 (29.66%), Postives = 104/236 (44.07%), Query Frame = -3
Query: 8024 NKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQ---FKILPRYKVKSEGEYVQIYDQIILESIKSPG--HFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTS--------NSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILV 8692
++ + YG I L+ S Y+ TT S DK V L D T + + I P K +SEGE V++ D +IL S+ S H +AS +D M + N+ SG + + Y + GG ++LFH M D+C L I DQ A R + + A + W++E + SG + W Q FR RH TT YL++D+E ++LV
Sbjct: 91 HRTLLYGHAILLRHTHSSMYLSCLTTSRSLTDKLAFDVGL--QEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYASGDLMVDASFMQTLWNMNPVCSGCELAEGY---------LTGGYVLRLFHGHM----------DEC------LAIPAADQ-GADQRRNAHYEGGAVCSHARSLWRLEPLRIGWSGSHIKWGQAFRIRHITTGRYLSLDDEKGLLLV 298
BLAST of SMED30029683 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003582.1 (pep scaffold:Pmarinus_7.0:GL477251:10655:41631:-1 gene:ENSPMAG00000003274.1 transcript:ENSPMAT00000003582.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.2117 bits (243), Expect = 2.259e-21 Identity = 95/366 (25.96%), Postives = 165/366 (45.08%), Query Frame = -3
Query: 7901 FQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEFEKSIISGDKLT-----WDQQFRFRHTTTRMYLAVD----------------------EESNVILVKESRDPRTVFKLHPVIQDSEEVT-FE----------------SYARIEHVLSGNWLHA 8866
F++ NRY K++L K A + D+ L + + AA+ E N +E ++ ++YG V+QL + S+KY+ VN + +KN M V LN ++ + F + P YK++S G+ V + D+++L + + G HAS +DN E+N + + I + + E ++GG V+LFH E E ++ + D ++ H+ +R + +A T TS+ A+ W+IE ++ D W+ FRF+H T YLA + E + + S+ R +F L PV S+ + FE SY R+ H+ + W+H+
Sbjct: 39 FRMCPMNRYSAQKQFL-KAAKPAIHSSTDS---LLLKKLQHAADLEKKQNESENKKLLGTVIQYGNVVQLLHMKSNKYMTVNKRLPALLEKNAMRVVLNGSGNEGSWFYVQPFYKLRSMGDSVVVGDKVVLNPVNA-GQPLHASNYELVDNPGC-KEVNSVNCSTSWKISLFMTWSENKEDILKGGDVVRLFHAEQEKFLTS-----DEYRKKQHVFLRTTGRQSA-TSATSSKAL--WEIE----VVQHDPCREGAGHWNSLFRFKHLATGDYLAAEVTAWAPRNVSVPPPPRRSQADAEPAASSTSRSSKRDRMMFTLVPVDHGSDIASIFELDPTTMQRGDSLVPRNSYVRLRHLCTNTWVHS 386
BLAST of SMED30029683 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007822.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:181935:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007822.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 94.3597 bits (233), Expect = 6.126e-20 Identity = 56/160 (35.00%), Postives = 94/160 (58.75%), Query Frame = -3
Query: 1088 FSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSY--DFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSK---IDELLKNVSTLINHQKSEDSERK 1552
F VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC+ F++ FE H+ EHNMW+Y++F + ++ +YT + +VA +++E+ D+FP RA+ L + + + ++ + E L+ + LI+ S+ SE K
Sbjct: 281 FVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICAAGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSLVSSEGEGEQNEMRVLQEKLEMTARLISGLCSQLSELK 440 HSP 2 Score: 54.299 bits (129), Expect = 3.281e-7 Identity = 23/78 (29.49%), Postives = 47/78 (60.26%), Query Frame = -3
Query: 1670 FYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE 1903
++ + L G +F++ L ++V+ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + F E
Sbjct: 111 LFHLSYLIICALGLVMHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGFLFLKDDFVME 188
BLAST of SMED30029683 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007816.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:205429:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007816.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 93.9745 bits (232), Expect = 3.899e-19 Identity = 56/160 (35.00%), Postives = 94/160 (58.75%), Query Frame = -3
Query: 1088 FSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRN--SYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSK---IDELLKNVSTLINHQKSEDSERK 1552
F VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC+ F++ FE H+ EHNMW+Y++F + ++ +YT + +VA +++E+ D+FP RA+ L + + + ++ + E L+ + LI+ S+ SE K
Sbjct: 736 FVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICAAGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSLVSSEGEGEQNEMRVLQEKLEMTARLISGLCSQLSELK 895 HSP 2 Score: 90.5077 bits (223), Expect = 4.340e-18 Identity = 124/590 (21.02%), Postives = 251/590 (42.54%), Query Frame = -3
Query: 1670 IELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYAN-----------INKDTIDLVSQVFSTINEFVAG----NQENRVTVXXXXXXXXXXXILRGGN-YPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQ--YIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLD-PNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQ----QKAFKFYKKNSVSIELLKGD-YLQKVHFRIRNK-NIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLP----------DFFRNPVPDWKPRFENLKSWMFA--FGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE 3328
+E +L+ L +C+ +P LQ +LR Q +N ++NLV E +QFL+ + + IN+ + L++Q ++ E+ G NQ T N I I IL N + ++ELK N L+++++E + ++ A + + + + V+ +AY ES DG+ + +T+ YI+A + E+ + L E L L D+ P+L + R + ++ L ++ +Q +A +Y K++ IE+++ D ++++ F + N + + K V +R +KI DF S + +++ +QK+ + ++W + L+V +NL++ +F FN S +LP + PR ++++ + L+ +V C +L A+ + F+ ++ G + M + ++ LG + +F++ L ++V+ + L VI +VT+NG+S++ A+L ++++YL++I+GF F + F E
Sbjct: 99 MEPILRFLQLLCENHNPALQNFLRCQ-NNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINERNVGLINQTLESLTEYCQGPCHENQNCIATHESNGIDIIIALILNDINPLGKDRMELVLELKDNASKLLLAIMESRHD--SENAERILYNMRPKELVAVIKKAYHQEGEES--EDGVVEEQSTSPKEVGHNIYILAHQVGTGEVNSAR-HLSET-------LTGLKDMSSPSLAAQ------------LARHNKELDQMLHLSSSQGEEGSEALDYYTKHTSQIEIVRHDRVMEEIVFPVPNVCEFLTSQSKTRVYLTTERDDQGSKISDFFQSSHELFSEMVWQKQLRGRALLFLAVALPVVWGTISSNLTVFMNLLV----------AFFYPFNSSSGGGTLPLRLSGLLWLAVLVVLALVVLLPRPHSVRALVVVVILRLIFSVGCQPILILLGTANVLNKVVFLVSFV-------------GNKGTFTHGYQAMVMDVEFLFHLSYLIICALGLVM-----HEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGFLFLKDDFVME 635
BLAST of SMED30029683 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010602.1 (pep scaffold:Pmarinus_7.0:GL476450:29:322425:-1 gene:ENSPMAG00000009553.1 transcript:ENSPMAT00000010602.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 83.5741 bits (205), Expect = 8.405e-16 Identity = 81/283 (28.62%), Postives = 121/283 (42.76%), Query Frame = -3
Query: 7907 NKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQ---FKILPRYKVKSEGEYVQIYDQIILESIKSPG--HFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILV-KESRDPRT-VFKLHPVIQ-------------DSEEVTF-ESYARIEHVLSGNWL 8692
++ + YG I L+ S Y+ T S DK V L D T + + I P K +SEGE V++ D +IL SI S H HA+ ++D + N+ SG + + Y + GG ++LFH E V D VH + +AR+L W++E + SG+ L W Q FR RH TT YLA+ EE ++LV + D +T F + + S E+ + +S ++HV SG WL
Sbjct: 82 HRTLLYGHAIILRHAHSGMYLSCLRTSHSSSDKLAFDVGL--QEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSISSERYLHLSHANGSLHVDASFQQTLWNVSPVCSGSEMAQGY---------LIGGDVLRLFHGHDECVTVPPADRGDEHRRSVHYEGGAVCS-HARSL---------WRLETLRVSWSGNHLHWGQPFRLRHVTTGKYLALTEERVLLLVDRGCADVKTSAFSMRSSKEKLDSGPRRDIDGMGSPEIKYGDSVCYMQHVESGRWL 343
BLAST of SMED30029683 vs. Ensembl Nematostella
Match: EDO37876 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEK1]) HSP 1 Score: 155.606 bits (392), Expect = 2.463e-37 Identity = 193/820 (23.54%), Postives = 336/820 (40.98%), Query Frame = -3
Query: 6797 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESN------------------VILVKESRDPRTVFKLHP--VIQDSEEVTFESYARIEHVLSGNWLHALK---DKEYKRQQF------STTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLE----------------CYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQR--------WLLEDRRG---------------------VYLT-ERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVD 9013
IGD + LY E G++ ST ++ + N P D F+I NRY K++ + A + DA L + AAE E N +E ++ + V+YG V+QL V S+K++ VN + ++KN M V+L+P+ ++ + F I+P YK+++ G+ V + D +IL + + G HAS +DN E+N Q+ + I S+ + E ++GG V+LFH E E ++ D ++ ++ +R + +T ++ S+ W++E + G W+ FRF+H T YLA + + + ++ D ++F+L P + + V SY R+ H+ + W+H+ DK +R S ED+ + + E+R +D +DA + + N+ F+ LL D + H V + + RQKL+R ++ + LL P D+ N + +E CY +L + RKN Y AK + Q+ + I +L+ +NRK++++ I++ +I FV +R + R+L+ L LCV N I Q I + L+E G V+L ERG+ + Q +I +K I + +DY Y QL+LF+ +C R I I+K L + + + LP D+RA +C +++ + +D
Sbjct: 10 IGDIVSLYAEGNVTGFI---STLGLIDDRCVVQPGAGDLSNPPKKFRD---CLFKICPMNRYSAQKQFWK--AAKPTTSATDA---VLLKKLHHAAELEKKQNESEYKKMLSSVVQYGSVMQLLHVKSNKFLTVNKRLPALREKNAMRVTLDPNGNEGSWFYIVPFYKLRAAGDNVVVGDMVILNPVNA-GQPLHASNQELIDN-PGCKEVNCVNCQTSWKISLFLSYDENDEDILKGGDVVRLFHAEQEKFLTC-----DDFKKKSYIFLRTTAR---QTATSATSSKALWEVEVVQHDPCRGGAGHWNCLFRFKHLATGDYLAAEADDDNTKDATRHKLKGSDPVFHLVPAPHGNDIASIFELDPTTLTRSDSLVPRCSYVRLRHLCTNTWVHSTGIPIDKGEERPVMLKIGTASIKEDKEAFAIVPVPALEVRDLDFA-----NDASKVLGTFASKLETGNYTQHERRFVTQLLTDLVYFVTEHDTGGEDV---------LNIQVQDPNRDRQKLMREQNILKEVFHLLKAPF---TDKGNGPMLRIEELSDQRNAPLRHIFRLCYRVL-RHSQQDYRKNQEYIAKQFGFMQAQI----GYDILAEDTITDLVHNNRKLLEKHITRTEIETFVSLVRKKKECRFLDYLSDLCVSNHTAIPATQELICKTVLHPSNSDLLIETSMGDVLLVWEMNNGKRCVPGLGEYVFLVWERGEKMKAQKDIAKGVKMMVKEDIKI-----LDYYRY----------QLNLFSQMCLDRQYLAINSISKQLDV---DLILRCMADKELPCDLRAAFCRLMLHMHID 768 HSP 2 Score: 152.14 bits (383), Expect = 2.609e-36 Identity = 127/523 (24.28%), Postives = 242/523 (46.27%), Query Frame = -3
Query: 1013 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFK-APKDGSFDENFNISKYNNSLPDF---FRNPVPDWKPRF--ENLKSWMFAFGL--------VHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE-----------------KNLYCDSLWHCFVSVMRFGLV-GDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLT---AKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSL 2476
+ +E K V +R ++K+ DF ++ + ++++QKK + + + LW +V++NL++ + + G D +I + L F P P F + +F+ GL + NV+ + F+ + + QY ++R L EL I T++ F +LG ++ +F++ L++++ L VI +VT+NG+S+I IL ++++Y+++I+GF F + F E K CD+L C V+ + GL G ++L S K F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E +++TCFIC + F++ F+ H+ ++HNMW Y+++ + L+ ++T + +V+ + K++ D+FP +A+ L +E + + + L+N + L+ + S+ K E + ++R QK+ G L + L
Sbjct: 2127 LTDESKINVYATCERDDQNSKVSDFFHRTEDLFQEMQWQKKLREHRLLFGLSSRLSLWEQISINFAVLINLLVGFFYPFSDGPGDLDPRLSILVWLAMLVSFAIIITFPRPSGIRTFVGSTILRLIFSLGLEPTLRILGLANVINKAISVVSFVGNRGT---FQYG---VRRILTDKEL---------------------ILHLTYFGFGVLGLTV-----HTFFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPSIGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDVLRRRSSKEKM-FAGRVVYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLAIDEGGNEQNEMRNLQDKLENTTKLVQTLSQQLSDLK---EQMTEQRKQKQRMGLLGPQHGL 2613 HSP 3 Score: 89.7373 bits (221), Expect = 2.374e-17 Identity = 119/547 (21.76%), Postives = 234/547 (42.78%), Query Frame = -3
Query: 4916 AIVNAKYAALEVLQMILNFESNARLAGFMAKFK----ECERNEGLLKKKNP------SSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WS---------------------------DEQVNRMENIFSELIEFC--HLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVM-------KYIMQSYS---SAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFI-----------GNLGEEIH---YLTQYILESPHELVYYLLTKPF 6361
++ K +E+L+ I+N + R++ + FK E N G + N S+ A A++ G SA L + R +L+ L + Y + +L++L +S +Q+ QA + +L++T ++++ + LR++ + W D+Q + I + + C + P ++ QR+L + VV+E+L + ++ + E ++ A + L+ L P Q+ + ++LD+ L L+ES+ TL+ +F++N LC ++ R + I+ E + + E+L LL +VK EG ++++ Q +VM + ++ YS S +++E RE + +E G + Y I+L++LL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI IW+ N+ + H L +Y+ E+ L+ + PF
Sbjct: 942 VVMETKLKVIEILEFIMNVRLDYRISSLLTIFKKDFDESNANIGDVNADNGIDLENISAQAEAIFGG-----SIGSADIDLDLDGQGGRTFLR------------VLLYLCMHDYPSLVTGSLQLLIRHFSQRQEVLQAFKQVQLLVSTSDVENYKQIRSDLDELRLLVEKSELWVYKSKKDSIGSTKKKKETADGDNDKEALDKQDKAAQQILQRISQLCVTYGPDDVKKNRKHEQRLLRNMGAHTVVLELLQI---PYAKDEDIRMEDIMALAHEFLQNFCLGNPQNQSLLHKHLDLFLTPGLLESQ---TLRYIFMDNSALCYEVTERVVQHIIH-CIESRGRHVEYLKLLQTLVKAEGQ--SIRKTQDMVMAELVNVGEDVLVFYSDTKSFNHLIEMMQSERERL--DEAGA--LLYHINLVQLLACCTEGKNVYTEIKCHSLLPLDDIVRVVTHEDCIPEVKNAYVNFLNHCYV-----DTEVEMKEIYTSNHIWRLFEDFLVDMARVCNNMMDRYHADTMLEKYVTETIMNLITFFFNSPF 1453
BLAST of SMED30029683 vs. Ensembl Nematostella
Match: EDO28592 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T616]) HSP 1 Score: 147.902 bits (372), Expect = 8.894e-36 Identity = 124/522 (23.75%), Postives = 239/522 (45.79%), Query Frame = -3
Query: 1013 IREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFK-APKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTE-----------------------------KNLYCDSLWHCFVSVMRFGLV-GDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLT---AKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSL 2476
+ +E K V +R ++K+ DF ++ + ++++QKK + + + LW +V++NL++ + + G D +I + L F + PR ++++ V L + L P+ RI +I + + + Q G LI T++ F +LG ++ +F++ L++++ L VI +VT+NG+S+I IL ++++Y+++I+GF F + F E K CD+L C V+ + GL G ++L S K F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E +++TCFIC + F++ F+ H+ ++HNMW Y+++ + L+ ++T + +V+ + K++ D+FP +A+ L +E + + + L+N + L+ + S+ K E + ++R QK+ G L + L
Sbjct: 263 LTDESKINVYATCERDDQNSKVSDFFHRTEDLFQEMQWQKKLREHRLLFGLSSRLSLWEQISINFAVLINLLVGFFYPFSDGPGDLDPRLSILVWLAMLVSF---AIIITFPRPSGIRTF---------VGSTILRLIFSLGLEPTL-RILGLANVINKAISVVSF-VGNRGTFQYGVRRILTDKELILHLTYFGFGVLGLTV-----HTFFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPSIGSPRGGVCASSGGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDVLRRRSSKEKM-FAGRVVYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLAIDEGGNEQNEMRNLQDKLENTTKLVQTLSQQLSDLK---EQMTEQRKQKQRMGLLGPQHGL 761
BLAST of SMED30029683 vs. Ensembl Medaka
Match: itpr1b (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101155104]) HSP 1 Score: 226.868 bits (577), Expect = 1.700e-58 Identity = 353/1536 (22.98%), Postives = 628/1536 (40.89%), Query Frame = -3
Query: 4916 IGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQP--SHIPDP----QMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVD------EESNVILVKESRDPR-----------------TVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALK---DKEYKRQ---QFSTTE---DERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPL-------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPN--ILYVSTDCMKSWI------------ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPER-SFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKI-----EHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLID--------------------------GSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF----ENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W-------------------SDEQVNR-------------MENIFSELIEFC-HLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEI--------------HYLTQYILESPHELVYYLLTKPF 9013
IGD LY E STS F + L + + QP + +P + F++ NRY K++ K A + D L ++ AA+ E N +E R+ ++YG VIQL + S+KY+ VN + +KN M V+L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + +V D E ++GG V+LFH E E ++ DD +Q H+ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA + EE+N L R P+ ++F+L P + V SY R++H+ + W+H+ DKE ++ + T+E D+ + + E+R +D +DA + F+ LLED + F + + +++ E M+ K + RQKL+R ++ + KLL P G A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV I Q I +L+ L E I N I + D + W+ ++ + Q G D E V + QL+LF +C R I I+ L + + E LP D+RA +C +++ + VD V P + + ++ + +K +D + ++ F D++ +L E +++ I E N L +V+ L L+ FG+Y + D+ L L+ ++D G LP P Q + ++V+ + +R E +++ K +E+LQ ILN + R++ + FK CE +E +N + +L F+ +E I+E E E T + +D +L++L + Y + AL +L +S +Q+ A + +L+T+ ++++ + LR + + W + ++V+R ++ I L + C ++ QR+L + VV+E+L + EK + + +++ A + L+ Q + +++++ L ++E A+T++ +F+NN LC +I R + V H + ++L L IVK E +K+ Q +VM ++ S Y+ A L Q M + + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ V+ H + +K ++ +L Y+ +E EI +W+ N +I L +Y+ E+ +V + PF
Sbjct: 11 IGDICSLYAEG--------STSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFW-KAAKPGGNSTTDT---VLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSLGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKVVLFMKWSDNKETILKGGDVVRLFHAEQEKFLTC----DDHKKKQ-HVFLRTTGRQSA-TSATSSKAL--WEVEVVHRDPCRGGAGYWNSLFRFKHLATGCYLAAEVNPDFEEENNEALRGRLRTPQEKVMCTLVPVPDGMEISSIFELDPTTLRGGDSMVPRSSYVRLKHLFTNTWVHSTNNPIDKEEEKPVMLRIGTSEVKEDKEAFAIVPVPPAEVRDLDFA-----NDASKVLASIAGKLEKGTITQNERRFVTKLLEDLV---FF----VVDIPNSGQDVLEIMV--NKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVTLVRKNREPRFLDYLSDLCVSMSKSIPVTQELICNA-VLDSNNADILIETKFEIETSTNGDIPLQAEDEEEVWLFWKDNAKDIRSKSVRELAQDAREGQKEDQEVVSYYRCQLNLFARMCLDRQYLAINKISNQLDV---DLILRCMSDEDLPFDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSKIAIDDYDNDGNSRDEIKERFSLTMDFVENYLRE---VVSQNIPFTDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLNILDCVHVTGSNVMKSIHGVGELMTQVVLRGGGLLPTAPAHQ------PEGEVVKTQTEPER-----EDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFK-CEFDENNPPGENAPNQIPSLTGNFD-FEN-----------IEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSIVEKSELWVYKRQGEDGMDGDGPSESENKKKVSRTKSAVDNSYNYRVVKEILIRLSKLCVQEGSTGKKSKKQQQRLLRNMGAHSVVLELLQIP-----YEKDVRMQDIMKLAHEFLQNFCAGNQPNQALLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINERVVQHFVHCTESHGRHV-QYLKFLQTIVKAE--NKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFENFLVDICRVCNTTSDRKHADTMLERYVTETVMSIVTCFFSSPF 1452 HSP 2 Score: 172.555 bits (436), Expect = 4.282e-42 Identity = 101/343 (29.45%), Postives = 169/343 (49.27%), Query Frame = -3
Query: 1013 FYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF---------------------NT--------------------EKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSL 1903
Y I G G + +F++ L ++V+ + L VI +VT+NG+S++ A+L ++++YL++I+G+ FF+ F NT +K CDSL C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHNMW Y+FF + ++ + +YT + +VA +++E D+FP RA+ L + D D ++I L + + + + + S+ +E + ++R QK+ G L +
Sbjct: 2285 LLYLIICGL---GVFVHVFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILAVDRIPNKTLGTTEAHFQLNTLTLSSQPCPKLSFHPSVVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIREHNLDWFPRMRAMSLVSSDADGEQNEIRNLQEKLESTMKLVTNLSSQLTELKEQMTEQRKQKQRIGLLGQPAHM 2619
BLAST of SMED30029683 vs. Ensembl Medaka
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192]) HSP 1 Score: 197.593 bits (501), Expect = 7.070e-50 Identity = 154/570 (27.02%), Postives = 269/570 (47.19%), Query Frame = -3
Query: 1028 NQQKAFKFYKKNSVSIELLKGD-YLQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFI-LIKRRLKQNELDPA-----DEDIIQQ--------GDEGCKMRSH--LISSKTF-YYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKN------------------------LYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSK---IDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLS 2584
+++ A +Y K++ IE+++ D ++++ F + N I EE K V +R +K+ DF ++ N++++QKK N + +F+ LW L+ +LN ++ T + DG DE S +N +L W + G LFT L P P I ++ + LI R + L PA ++ + G++G R + ++ F Y+ A + G + +F++F L ++V + L VI +VT+NG+S+ A+L + ++Y ++IIGF F + F E + CD+L C ++V+ GL VGD+ P E F+ V+Y L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ +EHNMW Y++F + ++ +YT + +VA ++ E+ ++FP RA+ L + + D+ ++ + E L N TLI+ S+ +E K E + ++R K+ GFL+
Sbjct: 1049 DREDALHYYAKHTAQIEIVRHDRTMEQIVFPVPNICEYITEESKMRVFTTTERDDQGSKVNDFFQQFDNLYNEMKWQKKIRKNRVLFWFSSHISLWGSISFYLANLLNFVVATFYPFGDDG--DEGTLSSMWNITL----------WA-----------SLG----------LFTALLPVFPKPWGILFFLVSLILRAIYTMGLAPALFLLGSVNLFNKLVFLASFVGNQGTFTRGYKAVVMDMLFVYHLAYAIICVLGLFVHEFFYSFLLFDLVSREETLLNVIKSVTRNGRSIFLTAVLAIFLVYFFSIIGFLFLKDDFRMEVDPLPLPGHPSQDTCLCERCEDDGMERVCDTLLMCIITVLNQGLRNGGGVGDILRR--PSKEEP---LFAARVVYDLLFFFVVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIAEKNLEWFPRMRAMSLVSNEGDNEQNEMRSLQEKLTNTVTLISQLSSQLAELK---EQMTEQRKNKQRMGFLA 1577 HSP 2 Score: 67.781 bits (164), Expect = 2.366e-10 Identity = 59/219 (26.94%), Postives = 105/219 (47.95%), Query Frame = -3
Query: 4997 QNQIF--ENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYS---------SAAYILEQPMETREAVLKEELGEDH-VQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNL 5617
QNQ+ ++L++ L L+E+E T++ +F+NN LC +I R +H V H + ++L L IVK +G +K+ Q VM ++ + S+ +L+ M + +E ED + Y +L+ELL+ C EG+N Y E C ++L ++DI+ V+ +K ++ ++ Y+ +E EI IW+ N
Sbjct: 179 QNQVLLHKHLNLFLTPGLLEAE---TMRHIFMNNYQLCNEISDRVVHHYVHCIETHGRHT-KYLKFLETIVKSDGK--YVKKCQDKVMTELVNAGEDVLVFYNDRSSFQVLKDLMRSE----RERSDEDGALAYHNTLVELLAACTEGKNVYTELKCNSLLPLDDIVKVVTEENCVPEVKTAYVNFVNHCYV-----DTEVEMKEIYTSCHIWKLFDNF 382
BLAST of SMED30029683 vs. Ensembl Medaka
Match: itpr1a (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101167700]) HSP 1 Score: 197.978 bits (502), Expect = 9.595e-50 Identity = 348/1556 (22.37%), Postives = 629/1556 (40.42%), Query Frame = -3
Query: 4916 IGDFICLYCE-ETDGYVYSMSTSSFFNNLAIYHKQD---RNQPSHIPDPQMITFQISIQNRYKLNKKYLRKFANIEDENVLDADTRQLCDQAKAAAEAENVDNLAEQRRNQNKKVRYGEVIQLKQVFSDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIEF-EKSIISGDKLTWDQQFRFRHTTTRMYLAVD-----EESN----------------------VILVKESRDPRTVFKLHPVIQDSEE--VTFESYARIEHVLSGNWLHALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFML---VNGKSV---------KARQKLLRNLRVIDLLVKLLNMPL-------------YGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCV-------------CNGVGIVDNQTYIAQRWLLEDR---RGVYLTERGQNIHEQPNILYV-STDCMKSWI---ALHKFLQVDYPGY--DDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPER-SFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSR-DLPFPPERQGKELSKEK----------KKIVQKYQQGDRYLQS------------------KETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKE--CERNE-------GLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQ-----MTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--W------SDEQVNRMENIFSELIEFCHLPKAPEEPHPMN-----------------------------QRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQ--IFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQS-------YSSAAYI--LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH--------------YLTQYILESPHELVYYLLTKPF 9013
IGD LY E T+G++ ST ++ + N P D F++ NRY K++ + + + + L ++ AA+ E N +E ++ ++YG VIQL + S+KY+ VN + +KN M V L+ ++ + F I P YK++S G+ V I D+++L + + G HAS +DN +E+N + + IV D E ++GG V+LFH E E ++ DD +Q ++ +R + +A T TS+ A+ W++E + G W+ FRF+H T YLA + EE ++ V + D ++F+L P + V SY R+ H+ + W+H+ Q E++ M I G K D +A+ I V P R +F L ++ +L++ + E V ++ F++ NG+ V + RQK++R ++ + KLL P G A F + CY +L + RKN Y AK + Q+ + I L+ +NRK++++ I+ +I+ FV +R N R+L+ L LCV CN V N + + L+ R +GV L E E +++ + K I ++ + Q G D E + + QL+LF +C R I I+ L + + E LP D+RA +C M++ + VD V P + + ++ + K + +D + ++ F +++ +L + + E N L +V+ L L+ FG+Y + D+ L L+G++D + +Q KE SK + + Q +G +L + K+ +++ K +E+LQ ILN + R++ ++ FK ERN G+++ +N ++ AL F E++ + E + +D +L++L + Y + AL +L +S +Q+ QA + +L+T+ ++++ + LR + + W DE ++ + + SE + H K E N QR+L + VV+E+L + + + K+ + LQ A + QNQ + +++++ L ++E A+T++ +F+NN LC +I R + V H + ++L L IVK E +K+ Q +VM ++ + Y+ A L M++ + E + Y I L+ELL+ C EG+N Y E C ++L ++DI+ ++ + + +K ++ +L Y+ +E EI +W+ N +I L QY+ E+ +V + PF
Sbjct: 11 IGDICSLYAEGSTNGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRD---CLFKLCPMNRYSAQKQFWKAAKPGGNTDTV------LLNKLHHAADLEKKQNDSENKKLLGSVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVMLDTAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN-PGCNEVNSVNCNTSWKIVLFMKWGDNQEVVLKGGDVVRLFHAEQEKFLTC----DDHRKKQ-YVFLRTTGRQSA-TSATSSKAL--WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPEYEEERPDNQHEALRARLRCAQEKVMYALVAVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHS------TNQPIDKEEEKPVMLRI---GTSPHKED-------KEAFAIVPVSPAEVRDLDFANDASKVLASI-AGKLEKGTITQNERRAVTKLLEDLVFFVVDIPNNGQDVLEIMVNKHNRERQKVMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVL-RHSQQDYRKNQEYIAKQFRFMQKQI----GYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVNLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEIQGVPLGENSVESEEDEEEVWLFWKENNKKEIRSKSIRELAQDAKEGQKEDKEVISYYRYQLNLFARMCLDRQYLAINKIS---CQLDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVT--PVKYARLWSEIPLKISIEDYDNDGTSKDEIKERFSQTMEFVETYLRNVVSPNLSFGNKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLGILDCVHVGAIYSFNKQEKEDSKGSNVMRSIHGVGELMSQVVLRGGGFLPTTTVNTSNGEAVKTQIEPEKQDILVMDTKLKIIEILQFILNVRLDYRISCLLSIFKTEFDERNSQSDLSINGVIESQN--NMQGAL--DFEHMEEQAEGIFGGS----------EQNNPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYKRLGPDEGMDGGDALASEHKKV-HWGKKTESTSSYNYRVVKEILLRLSKLCVQEGPTGRKNRKQQQRLLRNMGAHAVVLELLQIPYEKGEDLRMQDIMKLAHQFLQNFCA-----GNQQNQALLHKHINLFLNPGILE---AVTMQHIFMNNFQLCSEINDRVVQHFVHCIETHGRNV-QYLKFLQTIVKAE--NKFIKKCQDIVMAELVNAGEDVLVFYNDRASFQTLVHMMQSERDRMDE---NSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRIVTNEDCIPEVKIAYINFLNHCYV-----DTEVEMKEIYTSNHMWKLFDNFLVDICRVCNNTSDRKHSDVILEQYVTETVMSIVTTFFSSPF 1482 HSP 2 Score: 171.014 bits (432), Expect = 1.350e-41 Identity = 128/536 (23.88%), Postives = 241/536 (44.96%), Query Frame = -3
Query: 1025 EVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVF--KAPKDGSFDENFN----ISKYNN-SLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF-------------------------------------------NTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSN 2467
E K V + +R +KI DF ++ + N++ +QKK P+ + + +W+ L+V++NL++ + + G D + + I + ++ P+ F + +F+ GL + FLL + + + +I + + R G ++ ++ + Y+ L G + +F++ L ++V+ + L VI +VT+NG+S++ A+L ++++YL++I+G+ FF+ F N E+ CDSL C V+V+ GL VGD+ P E F+ VIY L FF ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H++ EH+MW Y++F + ++ + +YT + +VA ++KE D+FP RA+ L + D + ++I L + + + + + +E + ++R QK+ G L +
Sbjct: 2148 ESKLRVYYTTERDEQGSKINDFFLRAEDLFNEMNWQKKLRAQPVLYWCSRNMSVWSNISFNLAVLMNLLVCFFYPLEGVHGGMLDPHLSALLWIGVFATLAIVILMPQPLGIRALVFVTILRLIFSVGLEPTL---FLLGAFNVCN-----KIIFMISFVGNR----------------GTFTRGYKAMVMDFEFLYHLLYLIICCLGVFGHVFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILEVDRIPNITLSADDADGELLSAVCHNGAGENCSTAVHEEDSNMERT--CDSLLMCIVTVLSHGLRSGGGVGDVLRK--PSKEEP---LFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIMEEHSMWHYLYFIVLVKVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNEIRSLQDKLDSTMKLVANLSGQLTELKEQMTEQRKQKQRIGLLGH 2652
BLAST of SMED30029683 vs. Ensembl Medaka
Match: itpr3 (inositol 1,4,5-trisphosphate receptor type 3 [Source:NCBI gene;Acc:101170574]) HSP 1 Score: 177.563 bits (449), Expect = 1.466e-43 Identity = 293/1361 (21.53%), Postives = 561/1361 (41.22%), Query Frame = -3
Query: 4880 SDKYIHVNTTQTSQKDKNNMMVSLNPHNDKTAQFKILPRYKVKSEGEYVQIYDQIILESIKSPGHFFHASLPFYLDNFLMGSELNLGVEQSGFTIVKSYSHFDESEPFVRGGQFVQLFHKEMEAYIVAEGLFDDCVTEQVHLRIREIDQLNARTLRTSNSAITYWQIE-FEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEES--------------NVILVKESRDPRTVFKLHP-VIQDSEEVTFESYARIEHVLSGNWLHALK---DKEYKR------QQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLEDRLKEKFLHAKEAYRVCMAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNM----------PLY-----GQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDR-ISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKS--WIALHKFLQVDYPG-YDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVV--------DHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMF--ENTTQVKID-----QMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSK--WSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILS---VETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYP--DVQNQ-----------------------IFENLDMLLRV-KLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIH-------------YLTQYILESPHELVYYLLTKPFPKH---LKTHLTCSI 8644
S+KY+ VN + +KN M V+L+ ++ + I P +K+++ G+ V + D++IL + + G HAS + L++ E+N + + I D E ++GG V+LFH E E ++ D ++H+ +R + +A + +SN+ W+IE G W+ +RF+H T YLA + + ++++ + D ++F+L P +Q ++ SY R+ H+ + W+ + D + +R T ED+ + + E+R +D +D + ++++ + P DR K L + +A +V K + RQKL+R ++ + +L PL+ G +++ + CY +L + RKN + AK + + Q+ + I L+ +NRK++++ I+K ++ FV +RTN +L+ L LCV N V I Q I + L + Q+I + + + TD +K ++ + Q G DE V QL LF +C R I I+K L E FL + E+LP D+RA +C +++ VD V S +Y D ++ +++A +F + +++ L N M +E N L +V+ L L+ FG+Y ++ L L+G+ID SR P P G + Q+G++ K +++ K LE+LQ ILN + RL+ ++ F KK+ A + E + + + Q++ ++ MF + + +++D +LI+L ++YA + AL++L +S +Q+ + +L++ ++ + + LR + + W +++ + + + + + + ++P P +++ + +V EIL S + +K + K + +L + + Y DV+ Q + +NL++ L +L+E+E T++ +F NN LC +I + + A H + ++L+ L I+K E G +K+ Q ++M +Y ISL+ELL+ CAEG+N Y E C ++L +ED++ V+ H + +K ++ ++ Y+ +E EI IW + ++ L +YI+ + + + PF ++ L+TH T I
Sbjct: 36 SNKYLTVNKRLPALLEKNAMRVTLDGTGNEGSWLFIQPFWKLRANGDNVLVGDKVILNPVNA-GQPLHAS-NYDLNDHSGCKEVNSVNCNTSWKINLFMMFSDHREDVLKGGDVVRLFHAEQEKFLTC-----DEYKSKLHVFLRTTLRQSATSATSSNA---LWEIEVVHHDPCRGGAGHWNSLYRFKHLATGNYLAAEMDGRRISKRSQGERIKYKLVVLSDGNDIASLFELDPTTLQKTDSFVPNSYVRLRHLCTNTWIQSTNVPIDIDEERPIRLMLGTCPTKEDKEAFAIVSVPVMEIRDLDFANDASAMLSTVVEQLTRGFISP---------------NDRFAIKLLEDVVFFVTDVANAGQSVLDVVMKKPNRERQKLMREQNILKQIFGILKTPSAKREGGEAPLFRLEELGDQKNSHYQYMFQLCYRVL-RHSQEDYRKNQ-HIAKQFGMMQGQI----GYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRTNRE-PFLDYLSDLCVSNNVAIPVTQELICK---------CVLDPKNQDILIK-TVWLLWTDKIKEKHEKSIRQLAQEARQGNTHDENVLTYYYQLKLFARMCLDRQYLAIDEISKQLDV---ELIFLCMMDEMLPFDLRASFCRLMLHAHVDRDPQELVTPVKFARLWTEIPTSISIKYDSNMDDSRDNKKNRFAN---TMVF--MEEYLNNVL--NDEMPFHNVEKNKLTYEVVSLARHLIYFGFYS-FFELLRLTRTLLGIID-SRPNPGHP---GPIFQDDGPA-----QRGNKDSLEKMDLTVMDTKSKILEILQFILNVRLDYRLSFLLSVF----------KKEFVDVYPMADADATTNME-QAATINLQRIG-EQAEAMFGIKGNSILEVDDEGGRMFLRVLIHLTMHEYAPLVSGALQLLFRHFSQRQEVLHTFKQVQLLISAQDVENYKLIKANLDRLRTLVEKSELWVEKKSSAGGDGKKDKKDKKEISEVSDKPTPTKEKLEKGNENYQMVKEILERLHRMCSSGVWKKQQRLLKNMGAHKVMLDLLQVSYDKNDVKMQEIIKYTHLFLQKFCMGNQENQALLHKNLNLFLNPGQLLEAE---TVQHIFSNNYQLCSEISESVLQHFIHCLATHGRHV-QYLNFLHTIIKAE--GKYVKKCQDMIM---------------------------------TEYHISLVELLAACAEGKNVYTEIKCTSLLPLEDVVKVVTHVDCITEVKTAYVNFVNHCYV-----DTEVEMKEIYTSNHIWNLFEDFTVDMARVCNKRESRLADPVLEKYIVNVVLDTINAFFSSPFSENSTSLQTHHTIVI 1278 HSP 2 Score: 143.665 bits (361), Expect = 2.247e-33 Identity = 90/302 (29.80%), Postives = 167/302 (55.30%), Query Frame = -3
Query: 1031 FYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF----NTEKNL--YCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFL 1903
Y+ A + S+ G + F++ L ++++ + L VI +VT+NG+S++ A+L ++++YL++I+GF + F + E NL CD+L C V+V+ GL VGD+ P ++ F V+Y L F+ ++ I LN+IFG+I+DTF++LR K E ++ TCFIC F++ FE H+ EHN+W+Y++F + L++ DYT + +VA ++K D+FP +A+ L D D +++ L + + + + ++ +E + ++R +++ GF+
Sbjct: 1997 LYHLAYVLTSILGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLCLKEDFIMEVDPESNLERACDTLLMCIVTVLNHGLRNGGGVGDVLRK--PSKDQEPLFPAR--VVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICLERD-KFDNKTVSFEEHINMEHNIWNYLYFIVLLREKNKTDYTGPESYVAHMMKNNNLDWFPRMQAMSLVVTDSDGEQNEMRILQDKLGSTMKVVTTLTAQLTELKEQMTEQRKRRQRMGFV 2293
BLAST of SMED30029683 vs. Ensembl Medaka
Match: ryr1b (ryanodine receptor 1 [Source:NCBI gene;Acc:101160087]) HSP 1 Score: 123.635 bits (309), Expect = 3.102e-27 Identity = 86/261 (32.95%), Postives = 135/261 (51.72%), Query Frame = -3
Query: 1172 LISSKTFYYFA-ILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNT-----EKNLYCDS-----LWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDED 1921
+ + TF Y + S+ G Y+ +F+A HL++I + L+ ++S+VT NGK L+ L VV+YLY ++ F FFR +N E ++ CD L+H +V V G +GD E+ P E + V++ ++FF + I L I +I+D F ELRD + DM CFIC S F+ GFE H L EHN+ +Y FF ++L + ++T + +V + +E+ +DFFP C + ED
Sbjct: 4425 VFTDNTFLYLVWYMVMSVLGH-YNNFFYACHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIED--PAGDEYELYR----VVFDITFFFFVIVI-LLAIIQLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANY-FFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGD--CFRKQYED 4674 HSP 2 Score: 59.3066 bits (142), Expect = 1.054e-7 Identity = 99/450 (22.00%), Postives = 173/450 (38.44%), Query Frame = -3
Query: 7013 NSAITYWQIEFEKSIISGDKLTWDQQFRFRHTTTRMYLAVDEESNVILV-----------------KESRD---PRTVFKLH-PVIQDSEEVTFESYARIEHVLSGNWL-HALKDKEYKRQQFSTTEDERSMHAIRWDGGELRKVDCVHDRRYDDAYTIQKVYPEYYRPFNFIAGIVPFLRNLLE--DRLKEKFLHAKEAYRVCMAFR----EIKEFML-----VNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTY------------------------------MIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEAL-RTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDY 8170
+ A + W++E + I SG + W Q FR RH TT YL +DEE +++V KE D R V + P I+ E + F ++HV +G WL +A D + R G R+V + DDA T+ + E + I + R + D L K +K V + +++ + + +Q LR+LR N Q + + + LEC D L Y +I +R N F ++ ++ LD+ E S +++++ ++ ++ ++++ I + I + L + N++ L++L+ LCVCNGV + NQ I + LL R + T +PNI + + + + + VDY
Sbjct: 27 SQARSLWRLEPLR-IWSGSHMKWGQSFRIRHITTGRYLCLDEEKGLMVVDPEKANTKLSAFCFRASKEKVDVAQKRDVEGMGIPEIKYGESMCF-----VQHVSTGLWLTYAALDAKAARL-----------------GMMKRRVILHQEGHMDDALTVSRSQTEESQAARMIYSTMGLFRQFIRGLDSLSGK---SKSLGTVSLPLAGVILSLQDLIFYFRPPEEELEHEEKQTKLRSLR---------NRQNLFQEEFQGMITIVLECIDRLNVYNTAAHFSEFAGEEAAESWKEIVNLLYELLSLIRGNRSNCALFCDNLDWLVSK-LDRLEAS-SILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLRSLCVCNGVAVRSNQNLITEN-LLPGRDLLLQTNIVNYATVRPNIFLGTCEGSTQYKKWYYEMMVDY 438
BLAST of SMED30029683 vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1) HSP 1 Score: 4608.9 bits (11953), Expect = 0.000e+0 Identity = 2341/2342 (99.96%), Postives = 2342/2342 (100.00%), Query Frame = -3
Query: 605 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 7630
MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLISRSKSKSIRGRRNRNKGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISK+NNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS
Sbjct: 1 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLISRSKSKSIRGRRNRNKGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 2342
BLAST of SMED30029683 vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1) HSP 1 Score: 4603.12 bits (11938), Expect = 0.000e+0 Identity = 2334/2353 (99.19%), Postives = 2335/2353 (99.24%), Query Frame = -3
Query: 605 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXX-----------XXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 7630
MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLISRSKSKSIR K LIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISK+NNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS
Sbjct: 1 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLISRSKSKSIRGRRNRNKVIGDSLIKTTKSLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 2353
BLAST of SMED30029683 vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1) HSP 1 Score: 4590.79 bits (11906), Expect = 0.000e+0 Identity = 2319/2349 (98.72%), Postives = 2320/2349 (98.77%), Query Frame = -3
Query: 605 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEK-------KIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 7630
MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEK KIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKK K LIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISK+NNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS
Sbjct: 1 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKNLFMISRKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKK-----------VIGDSLIKTTKSLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 2338
BLAST of SMED30029683 vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1) HSP 1 Score: 4590.02 bits (11904), Expect = 0.000e+0 Identity = 2315/2333 (99.23%), Postives = 2316/2333 (99.27%), Query Frame = -3
Query: 605 MLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 7603
MLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVL K LIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISK+NNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS
Sbjct: 1 MLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVL-ISRSKSKRDSLIKTTKSLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 2332
BLAST of SMED30029683 vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1) HSP 1 Score: 4524.15 bits (11733), Expect = 0.000e+0 Identity = 2290/2342 (97.78%), Postives = 2291/2342 (97.82%), Query Frame = -3
Query: 605 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVXXXXXXXXXXXXXQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEXXXXXXXIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTXXXXXXXXXXXXXXXXXXAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVXXXXXXXXXXXILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLXXXXXXXXXXXXXXXXXGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKYNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 7630
MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHE VKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKK K LIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISK+NNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS
Sbjct: 1 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFLQVDYPGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSSLACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVKLVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILESPHELVYYLLTKPFPKHLKTHLTCSICTELVSQDPKKPLKLNNENAILRVKEDEFRAHASIHYIFDSVMAFLHLYSRQVFLFDSEDNKSEKDVYDDLTRSMVNLCAALSPAMTQPHHLKAMIACVTHMIPKSTLPATIMEPVVEGIGKGGKIVDTITQMKEGNQEYYNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIKYKMADLLINQLHISATTTNFGNLATTGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQISRKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVNSLSNNSKTRQKVIKKEKNINGKVKHTPKATFRQSDGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGYIELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPDCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHE-----------------------------VKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKK-----------VIGDSLIKTTKSLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDIIQQGDEGCKMRSHLISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDDNENGLGLRQVSNCHHSSLLLRHDSTNDRIHHEPHEGAAHKSSKSKISSKPYSIPPHSESIGGESGDSDYAIGDEIPEKNDSIFCISPPNIQPDLDQAPILPAYPIDYPSDDPMKFLDDYAKHDSDGSMS 2302 The following BLAST results are available for this feature:
BLAST of SMED30029683 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SMED30029683 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SMED30029683 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SMED30029683 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SMED30029683 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SMED30029683 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SMED30029683 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SMED30029683 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SMED30029683 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SMED30029683 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of SMED30029683 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of SMED30029683 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of SMED30029683 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SMED30029683 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30029683 ID=SMED30029683|Name=SMED30029683|organism=Schmidtea mediterranea sexual|type=transcript|length=9372bpback to top protein sequence of SMED30029683-orf-1 >SMED30029683-orf-1 ID=SMED30029683-orf-1|Name=SMED30029683-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2810bp MADFLCIGDFICLYCEETDGYVYSMSTSSFFNNLAIYHKQDRNQPSHIPDback to top protein sequence of SMED30029683-orf-2 >SMED30029683-orf-2 ID=SMED30029683-orf-2|Name=SMED30029683-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=170bp MNTFRRNSALELSNLIKPSDLKLHSSPSNENLRKMDFACSNIVTKPFYLIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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