Nucleolysin TIA-1 isoform p40
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30029672 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Human
Match: TIA1 (TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802]) HSP 1 Score: 229.565 bits (584), Expect = 3.782e-69 Identity = 104/216 (48.15%), Postives = 152/216 (70.37%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV SS SNCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 86 SQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 292 HSP 2 Score: 69.707 bits (169), Expect = 4.237e-12 Identity = 47/179 (26.26%), Postives = 85/179 (47.49%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 170
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Human
Match: TIA1 (TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802]) HSP 1 Score: 224.172 bits (570), Expect = 5.839e-67 Identity = 102/219 (46.58%), Postives = 152/219 (69.41%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
T +S Q + +H+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV SS SNCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+ +NP + N +GYP
Sbjct: 95 TVVSTQR-SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INP--VQQNQIGYP 302 HSP 2 Score: 73.9442 bits (180), Expect = 1.637e-13 Identity = 48/180 (26.67%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAAS-SESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P +K + V + S+ + ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT-----PSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Human
Match: TIA1 (TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802]) HSP 1 Score: 222.631 bits (566), Expect = 1.908e-66 Identity = 102/219 (46.58%), Postives = 151/219 (68.95%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
T +S Q + +H+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV SS SNCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 95 TVVSTQR-SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 303 HSP 2 Score: 73.9442 bits (180), Expect = 1.663e-13 Identity = 48/180 (26.67%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAAS-SESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P +K + V + S+ + ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT-----PSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Human
Match: TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:11804]) HSP 1 Score: 219.164 bits (557), Expect = 3.162e-65 Identity = 99/219 (45.21%), Postives = 148/219 (67.58%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ---KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFS----IYINPVGY 1405
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FG++++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P + K L + +V SS NCT+Y GGI +GL ++L+R++F FG I+E+R+F EKGY+FVRF +HE A AI+ ++G + + KC WGKES D+ + Q + + +Y NP Y
Sbjct: 88 SQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQY 306 HSP 2 Score: 70.8626 bits (172), Expect = 1.495e-12 Identity = 48/189 (25.40%), Postives = 90/189 (47.62%), Query Frame = 2
Query: 773 IQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
+ ED ++VG+++ ++ + + FS G CK+I + + P Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W
Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 172
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Human
Match: TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:11804]) HSP 1 Score: 219.164 bits (557), Expect = 4.924e-65 Identity = 99/219 (45.21%), Postives = 148/219 (67.58%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ---KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFS----IYINPVGY 1405
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FG++++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P + K L + +V SS NCT+Y GGI +GL ++L+R++F FG I+E+R+F EKGY+FVRF +HE A AI+ ++G + + KC WGKES D+ + Q + + +Y NP Y
Sbjct: 105 SQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQY 323 HSP 2 Score: 62.7734 bits (151), Expect = 7.564e-10 Identity = 49/205 (23.90%), Postives = 90/205 (43.90%), Query Frame = 2
Query: 773 IQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDM----------------HTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
+ ED ++VG+++ ++ + + FS G CK+I + HT Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W
Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDP-YCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 189
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8]) HSP 1 Score: 204.912 bits (520), Expect = 3.450e-61 Identity = 93/187 (49.73%), Postives = 133/187 (71.12%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYN-----EVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGK 1327
DT+ H+H+FVGD++ E++ Q LRE F FG V++ K+I+D +T K KGYGFV+Y +EEAE A+ +MNG++LG R IRTNWA R+ PG +KP YN E++ +S N ++YVG I + L E+ +R+ F FG I EVRIFK +GYAFV+FD+ + A +AI++M+ ++VG QL +CSWGK
Sbjct: 17 DTTRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRK----PGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIAS-LTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 198
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8]) HSP 1 Score: 204.912 bits (520), Expect = 4.872e-61 Identity = 93/187 (49.73%), Postives = 133/187 (71.12%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYN-----EVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGK 1327
DT+ H+H+FVGD++ E++ Q LRE F FG V++ K+I+D +T K KGYGFV+Y +EEAE A+ +MNG++LG R IRTNWA R+ PG +KP YN E++ +S N ++YVG I + L E+ +R+ F FG I EVRIFK +GYAFV+FD+ + A +AI++M+ ++VG QL +CSWGK
Sbjct: 27 DTTRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRK----PGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIAS-LTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 208
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8]) HSP 1 Score: 204.912 bits (520), Expect = 3.002e-60 Identity = 93/187 (49.73%), Postives = 133/187 (71.12%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYN-----EVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGK 1327
DT+ H+H+FVGD++ E++ Q LRE F FG V++ K+I+D +T K KGYGFV+Y +EEAE A+ +MNG++LG R IRTNWA R+ PG +KP YN E++ +S N ++YVG I + L E+ +R+ F FG I EVRIFK +GYAFV+FD+ + A +AI++M+ ++VG QL +CSWGK
Sbjct: 98 DTTRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRK----PGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIAS-LTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 279
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8]) HSP 1 Score: 205.297 bits (521), Expect = 4.585e-60 Identity = 93/187 (49.73%), Postives = 133/187 (71.12%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYN-----EVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGK 1327
DT+ H+H+FVGD++ E++ Q LRE F FG V++ K+I+D +T K KGYGFV+Y +EEAE A+ +MNG++LG R IRTNWA R+ PG +KP YN E++ +S N ++YVG I + L E+ +R+ F FG I EVRIFK +GYAFV+FD+ + A +AI++M+ ++VG QL +CSWGK
Sbjct: 130 DTTRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRK----PGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIAS-LTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 311 HSP 2 Score: 93.2041 bits (230), Expect = 4.373e-20 Identity = 51/179 (28.49%), Postives = 96/179 (53.63%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG++ + F+ F+ G VT+ K+I D + P Y FV ++ +A +AL MN + L R+++ NWA+ PG+ Q +D F ++VG +++ + + LRE+F+ FGD+ + ++ ++ KGY FV + E A +AI +M+G+ +G + + +W
Sbjct: 48 LYVGNLDSTVTEDFIATLFNQIGSVTKTKVIFD-GSNDP--YAFVEFSDHGQASQALQTMNKRLLLDREMKVNWAVE-----PGQQQSKIDTTRHFH--------VFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNW 210
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Celegans
Match: tiar-3 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q93194]) HSP 1 Score: 192.971 bits (489), Expect = 6.097e-55 Identity = 89/219 (40.64%), Postives = 140/219 (63.93%), Query Frame = 2
Query: 767 ISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLT 1423
+ ++ DTS H+H+FVGD++ ++ + L+ F+ FG V+E K+I+D+ TQK KGYGFV++ K+ AE A+ MNGK++G R +RTNWA R+ + +++ L + +VF ++ N ++YVG I+ + LR+ F +GDI EVRIFK + YAFVR++ E AT+AI+ M+GKE+ +CSWG+ + N LNP I ++ + P L T
Sbjct: 215 MEMRIDTSKHFHVFVGDLSKDVSNELLKSTFTKFGEVSEAKVIRDVQTQKSKGYGFVSFPNKQNAENAIAGMNGKWIGKRAVRTNWAARKNSE---ENRDKLTFEQVFNSTKADNTSVYVGNISQQTTDADLRDLFSTYGDIAEVRIFKTQRYAFVRYEKKECATKAIMEMNGKEMAGNQVRCSWGR-----TQAVPNQALNPLPIDLSSLMMPTMLPT 425
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0334897) HSP 1 Score: 222.631 bits (566), Expect = 1.564e-65 Identity = 105/213 (49.30%), Postives = 147/213 (69.01%), Query Frame = 2
Query: 794 HYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITN---GLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL--KETSQNSILNPFSIYINPVGYPYSL 1417
+HIFVGD++ EIETQ LRE F+ FG +++C++++D T K KGYGFV++ K EAE A+ MNG++LG+R IRTNWA R+PP ++ KPL ++EV+ SS SNCT+YVGG+ + L EE+L+++F +G I E+R+FK+KGYAFVRF + E AT AI+ +H E+ +Q KCSWGKES D +T LN S G+PY +
Sbjct: 165 QFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPP-ASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALN--SAAAAAAGFPYGV 374
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0344218) HSP 1 Score: 223.016 bits (567), Expect = 1.742e-65 Identity = 105/213 (49.30%), Postives = 147/213 (69.01%), Query Frame = 2
Query: 794 HYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITN---GLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL--KETSQNSILNPFSIYINPVGYPYSL 1417
+HIFVGD++ EIETQ LRE F+ FG +++C++++D T K KGYGFV++ K EAE A+ MNG++LG+R IRTNWA R+PP ++ KPL ++EV+ SS SNCT+YVGG+ + L EE+L+++F +G I E+R+FK+KGYAFVRF + E AT AI+ +H E+ +Q KCSWGKES D +T LN S G+PY +
Sbjct: 165 QFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPP-ASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALN--SAAAAAAGFPYGV 374
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0112583) HSP 1 Score: 222.631 bits (566), Expect = 1.940e-65 Identity = 105/213 (49.30%), Postives = 147/213 (69.01%), Query Frame = 2
Query: 794 HYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITN---GLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL--KETSQNSILNPFSIYINPVGYPYSL 1417
+HIFVGD++ EIETQ LRE F+ FG +++C++++D T K KGYGFV++ K EAE A+ MNG++LG+R IRTNWA R+PP ++ KPL ++EV+ SS SNCT+YVGG+ + L EE+L+++F +G I E+R+FK+KGYAFVRF + E AT AI+ +H E+ +Q KCSWGKES D +T LN S G+PY +
Sbjct: 165 QFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPP-ASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALN--SAAAAAAGFPYGV 374
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0334896) HSP 1 Score: 222.631 bits (566), Expect = 2.565e-65 Identity = 105/213 (49.30%), Postives = 147/213 (69.01%), Query Frame = 2
Query: 794 HYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITN---GLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL--KETSQNSILNPFSIYINPVGYPYSL 1417
+HIFVGD++ EIETQ LRE F+ FG +++C++++D T K KGYGFV++ K EAE A+ MNG++LG+R IRTNWA R+PP ++ KPL ++EV+ SS SNCT+YVGG+ + L EE+L+++F +G I E+R+FK+KGYAFVRF + E AT AI+ +H E+ +Q KCSWGKES D +T LN S G+PY +
Sbjct: 165 QFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPP-ASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALN--SAAAAAAGFPYGV 374
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0344217) HSP 1 Score: 220.705 bits (561), Expect = 1.885e-63 Identity = 105/213 (49.30%), Postives = 147/213 (69.01%), Query Frame = 2
Query: 794 HYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITN---GLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL--KETSQNSILNPFSIYINPVGYPYSL 1417
+HIFVGD++ EIETQ LRE F+ FG +++C++++D T K KGYGFV++ K EAE A+ MNG++LG+R IRTNWA R+PP ++ KPL ++EV+ SS SNCT+YVGG+ + L EE+L+++F +G I E+R+FK+KGYAFVRF + E AT AI+ +H E+ +Q KCSWGKES D +T LN S G+PY +
Sbjct: 311 QFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPA-SKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALN--SAAAAAAGFPYGV 520
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Zebrafish
Match: tia1l (cytotoxic granule-associated RNA binding protein 1, like [Source:ZFIN;Acc:ZDB-GENE-030131-2167]) HSP 1 Score: 230.72 bits (587), Expect = 2.880e-70 Identity = 100/200 (50.00%), Postives = 143/200 (71.50%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPP----GKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD++PEI T +R F+ FG++++ +++KD+ T K KGYGF+++ K +AE A+ +MNG++LG RQIRTNWA R+P P G K L Y EV SS SNCT+Y GGI +GL ++L+R++F FG I+E+R+F EKGY+FVRFDSHEGA AI+ ++G + KC WGKE+ D++ Q
Sbjct: 88 SQKKDTSNHFHVFVGDLSPEISTDDVRAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQIRTNWATRKPSAPKSNNEGASSKHLSYEEVLNQSSPSNCTVYCGGIASGLSDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGKETADMRSMQQ 287 HSP 2 Score: 67.3958 bits (163), Expect = 1.041e-11 Identity = 46/179 (25.70%), Postives = 85/179 (47.49%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + + ++ NWA P KD + ++ ++VG ++ + + +R +F FG I + R+ K+ KGY F+ F + A AI +M+G+ +G + + +W
Sbjct: 11 LYVGNLSRDVTEALILQVFSQIGPCKSCKMILDTTGNDP--YCFVEFYENRHAAAALAAMNGRKILGKDMKVNWA--STPSSQKKD-------------TSNHFHVFVGDLSPEISTDDVRAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQIRTNW 172
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Zebrafish
Match: tia1l (cytotoxic granule-associated RNA binding protein 1, like [Source:ZFIN;Acc:ZDB-GENE-030131-2167]) HSP 1 Score: 229.95 bits (585), Expect = 6.782e-70 Identity = 99/200 (49.50%), Postives = 143/200 (71.50%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPP----GKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD++PEI T +R F+ FG++++ ++++D+ T K KGYGF+++ K +AE A+ +MNG++LG RQIRTNWA R+P P G K L Y EV SS SNCT+Y GGI +GL ++L+R++F FG I+E+R+F EKGY+FVRFDSHEGA AI+ ++G + KC WGKE+ D++ Q
Sbjct: 88 SQKKDTSNHFHVFVGDLSPEISTDDVRAAFAPFGKISDARVVRDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQIRTNWATRKPSAPKSNNEGASSKHLSYEEVLNQSSPSNCTVYCGGIASGLSDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGKETADMRSMQQ 287 HSP 2 Score: 66.6254 bits (161), Expect = 2.087e-11 Identity = 46/179 (25.70%), Postives = 84/179 (46.93%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF------KEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + + ++ NWA P KD + ++ ++VG ++ + + +R +F FG I + R+ K KGY F+ F + A AI +M+G+ +G + + +W
Sbjct: 11 LYVGNLSRDVTEALILQVFSQIGPCKSCKMILDTTGNDP--YCFVEFYENRHAAAALAAMNGRKILGKDMKVNWA--STPSSQKKD-------------TSNHFHVFVGDLSPEISTDDVRAAFAPFGKISDARVVRDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQIRTNW 172
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Zebrafish
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:ZFIN;Acc:ZDB-GENE-030131-1506]) HSP 1 Score: 229.18 bits (583), Expect = 3.876e-69 Identity = 99/194 (51.03%), Postives = 142/194 (73.20%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL 1342
S ++DTSNH+H+FVGD++PEI T +R F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L ++EV SS SNCT+Y GG+T GL E+L+R++F FG I+EVR+F +KGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+
Sbjct: 87 SQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKATYETNTKHLSFDEVVNQSSPSNCTVYCGGVTTGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFNSHESAAHAIVSVNGTSLEGHIVKCYWGKETTDM 280 HSP 2 Score: 72.7886 bits (177), Expect = 2.946e-13 Identity = 45/179 (25.14%), Postives = 84/179 (46.93%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + F G CK+I D P Y FV + A +L MNG+ + ++++ NWA P KD + ++ ++VG ++ + + +R +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 10 LYVGNLSRDVTEALIMQLFGQIGPCKSCKMIVDTAGNDP--YCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATS--PSSQKKD-------------TSNHFHVFVGDLSPEITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 171
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Zebrafish
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:ZFIN;Acc:ZDB-GENE-030131-1506]) HSP 1 Score: 228.794 bits (582), Expect = 6.705e-69 Identity = 99/194 (51.03%), Postives = 142/194 (73.20%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL 1342
S ++DTSNH+H+FVGD++PEI T +R F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L ++EV SS SNCT+Y GG+T GL E+L+R++F FG I+EVR+F +KGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+
Sbjct: 87 SQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKATYETNTKHLSFDEVVNQSSPSNCTVYCGGVTTGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFNSHESAAHAIVSVNGTSLEGHIVKCYWGKETTDM 280 HSP 2 Score: 71.633 bits (174), Expect = 6.970e-13 Identity = 45/178 (25.28%), Postives = 83/178 (46.63%), Query Frame = 2
Query: 806 FVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
+VG+++ ++ + + F G CK+I D P Y FV + A +L MNG+ + ++++ NWA P KD + ++ ++VG ++ + + +R +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 11 YVGNLSRDVTEALIMQLFGQIGPCKSCKMIVDTAGNDP--YCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWAT--SPSSQKKD-------------TSNHFHVFVGDLSPEITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 171
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Zebrafish
Match: tial1 (TIA1 cytotoxic granule-associated RNA binding protein-like 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1547]) HSP 1 Score: 220.32 bits (560), Expect = 6.592e-66 Identity = 98/199 (49.25%), Postives = 139/199 (69.85%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD++PEI T +R F+ FG++++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P K L ++EV SS NCT+Y GGI +GL E L+R++F FG I+E+R+F EKGY+F+RF SHE A AI+ ++G + + KC WGKES D+ + Q
Sbjct: 87 SQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQ 285 HSP 2 Score: 71.633 bits (174), Expect = 5.369e-13 Identity = 48/187 (25.67%), Postives = 91/187 (48.66%), Query Frame = 2
Query: 779 EDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
ED S+ ++VG+++ ++ + + F+ G CK+I + + P Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + + +R +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W
Sbjct: 2 EDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEHTSNDP--YCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 171
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890]) HSP 1 Score: 225.713 bits (574), Expect = 3.384e-69 Identity = 104/211 (49.29%), Postives = 147/211 (69.67%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESND-LKETSQNSILNPFSIYI 1390
S ++D +NH+H+FVGD++PEI T ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y EV SS SNCT+Y GG+T+GL E+L+R++F FG I+EVR+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D L Q S L SIY+
Sbjct: 47 SQKKDANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETPDMLNPVQQVSELFSCSIYV 257 HSP 2 Score: 56.6102 bits (135), Expect = 2.559e-8 Identity = 39/147 (26.53%), Postives = 67/147 (45.58%), Query Frame = 2
Query: 902 MHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWG 1324
M T Y FV + A +L MNG+ + ++++ NWA P +K D N F ++VG ++ + + ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 1 MDTAGNDPYCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWAT-----TPSSQKK--DANNHFH--------VFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWA 132
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890]) HSP 1 Score: 224.557 bits (571), Expect = 2.639e-67 Identity = 102/216 (47.22%), Postives = 147/216 (68.06%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL-------KETSQNSILNPFSIY 1387
S ++D +NH+H+FVGD++PEI T ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y EV SS SNCT+Y GG+T+GL E+L+R++F FG I+EVR+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ E SQ S P+ +
Sbjct: 88 SQKKDANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETPDMLNPVQQVSEASQISFPPPYGQW 303 HSP 2 Score: 74.3294 bits (181), Expect = 1.349e-13 Identity = 48/186 (25.81%), Postives = 87/186 (46.77%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
D + ++VG+++ ++ + + FS G CK+I D P Y FV + A +L MNG+ + ++++ NWA P +K D N F ++VG ++ + + ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 4 DDTKTILLYVGNLSRDVTEPLILQVFSQLGPCKSCKMIMDTAGNDP--YCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATT-----PSSQKK--DANNHFH--------VFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNW 172
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890]) HSP 1 Score: 224.557 bits (571), Expect = 2.955e-67 Identity = 102/216 (47.22%), Postives = 147/216 (68.06%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL-------KETSQNSILNPFSIY 1387
S ++D +NH+H+FVGD++PEI T ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y EV SS SNCT+Y GG+T+GL E+L+R++F FG I+EVR+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ E SQ S P+ +
Sbjct: 86 SQKKDANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETPDMLNPVQQVSEASQISFPPPYGQW 301 HSP 2 Score: 73.9442 bits (180), Expect = 1.470e-13 Identity = 47/179 (26.26%), Postives = 85/179 (47.49%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A +L MNG+ + ++++ NWA P +K D N F ++VG ++ + + ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEPLILQVFSQLGPCKSCKMIMDTAGNDP--YCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATT-----PSSQKK--DANNHFH--------VFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNW 170
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890]) HSP 1 Score: 223.402 bits (568), Expect = 3.443e-67 Identity = 97/194 (50.00%), Postives = 140/194 (72.16%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL 1342
S ++D +NH+H+FVGD++PEI T ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y EV SS SNCT+Y GG+T+GL E+L+R++F FG I+EVR+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+
Sbjct: 64 SQKKDANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETPDM 257 HSP 2 Score: 63.5438 bits (153), Expect = 3.023e-10 Identity = 46/163 (28.22%), Postives = 75/163 (46.01%), Query Frame = 2
Query: 857 FSLF--GRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
F LF G CK+I D P Y FV + A +L MNG+ + ++++ NWA P +K D N F ++VG ++ + + ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 3 FFLFQLGPCKSCKMIMDTAGNDP--YCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATT-----PSSQKK--DANNHFH--------VFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNW 148
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890]) HSP 1 Score: 224.557 bits (571), Expect = 3.619e-67 Identity = 101/213 (47.42%), Postives = 148/213 (69.48%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL----KETSQNSILNPFSIY 1387
S ++D +NH+H+FVGD++PEI T ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y EV SS SNCT+Y GG+T+GL E+L+R++F FG I+EVR+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ ++ SQ S P+ +
Sbjct: 99 SQKKDANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETPDMLNPVQQASQISFPPPYGQW 311 HSP 2 Score: 67.0106 bits (162), Expect = 2.844e-11 Identity = 45/171 (26.32%), Postives = 78/171 (45.61%), Query Frame = 2
Query: 827 EIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++ + + FS G CK+I D P Y FV + A +L MNG+ + ++++ NWA P +K D N F ++VG ++ + + ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 30 DVTEPLILQVFSQLGPCKSCKMIMDTAGNDP--YCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATT-----PSSQKK--DANNHFH--------VFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNW 183
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Mouse
Match: Tia1 (cytotoxic granule-associated RNA binding protein 1 [Source:MGI Symbol;Acc:MGI:107914]) HSP 1 Score: 229.18 bits (583), Expect = 4.277e-69 Identity = 103/216 (47.69%), Postives = 152/216 (70.37%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV + SS +NCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 88 SQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 294 HSP 2 Score: 72.4034 bits (176), Expect = 3.259e-13 Identity = 47/179 (26.26%), Postives = 86/179 (48.04%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D+ T Y FV + A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDVRTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 172
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Mouse
Match: Tia1 (cytotoxic granule-associated RNA binding protein 1 [Source:MGI Symbol;Acc:MGI:107914]) HSP 1 Score: 228.794 bits (582), Expect = 4.992e-69 Identity = 103/216 (47.69%), Postives = 152/216 (70.37%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV + SS +NCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 86 SQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 292 HSP 2 Score: 69.707 bits (169), Expect = 2.988e-12 Identity = 47/179 (26.26%), Postives = 85/179 (47.49%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 170
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Mouse
Match: Tia1 (cytotoxic granule-associated RNA binding protein 1 [Source:MGI Symbol;Acc:MGI:107914]) HSP 1 Score: 221.861 bits (564), Expect = 2.497e-66 Identity = 101/219 (46.12%), Postives = 151/219 (68.95%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
T +S Q + +H+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV + SS +NCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 95 TVVSTQR-SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 303 HSP 2 Score: 73.9442 bits (180), Expect = 1.114e-13 Identity = 48/180 (26.67%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAAS-SESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P +K + V + S+ + ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT-----PSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Mouse
Match: Tia1 (cytotoxic granule-associated RNA binding protein 1 [Source:MGI Symbol;Acc:MGI:107914]) HSP 1 Score: 221.861 bits (564), Expect = 2.567e-66 Identity = 101/219 (46.12%), Postives = 151/219 (68.95%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
T +S Q + +H+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV + SS +NCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 95 TVVSTQR-SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 303 HSP 2 Score: 74.3294 bits (181), Expect = 1.053e-13 Identity = 48/180 (26.67%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAAS-SESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P +K + V + S+ + ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT-----PSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Mouse
Match: Tial1 (Tia1 cytotoxic granule-associated RNA binding protein-like 1 [Source:MGI Symbol;Acc:MGI:107913]) HSP 1 Score: 219.164 bits (557), Expect = 7.218e-66 Identity = 99/219 (45.21%), Postives = 148/219 (67.58%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ---KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFS----IYINPVGY 1405
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FG++++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P + K L + +V SS NCT+Y GGI +GL ++L+R++F FG I+E+R+F EKGY+FVRF +HE A AI+ ++G + + KC WGKES D+ + Q + + +Y NP Y
Sbjct: 49 SQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQY 267 HSP 2 Score: 54.299 bits (129), Expect = 2.056e-7 Identity = 37/138 (26.81%), Postives = 66/138 (47.83%), Query Frame = 2
Query: 926 YGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W
Sbjct: 11 YCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 133
BLAST of Nucleolysin TIA-1 isoform p40 vs. UniProt/SwissProt
Match: sp|P31483|TIA1_HUMAN (Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3) HSP 1 Score: 222.631 bits (566), Expect = 9.163e-66 Identity = 102/219 (46.58%), Postives = 151/219 (68.95%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
T +S Q + +H+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV SS SNCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 95 TVVSTQR-SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 303 HSP 2 Score: 73.9442 bits (180), Expect = 7.985e-13 Identity = 48/180 (26.67%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAAS-SESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P +K + V + S+ + ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT-----PSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
BLAST of Nucleolysin TIA-1 isoform p40 vs. UniProt/SwissProt
Match: sp|P52912|TIA1_MOUSE (Nucleolysin TIA-1 OS=Mus musculus OX=10090 GN=Tia1 PE=1 SV=1) HSP 1 Score: 221.861 bits (564), Expect = 1.795e-65 Identity = 101/219 (46.12%), Postives = 151/219 (68.95%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYP 1408
T +S Q + +H+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P + K L Y+EV + SS +NCT+Y GG+T+GL E+L+R++F FG I+E+R+F +KGY+FVRF SHE A AI+ ++G + + KC WGKE+ D+ +NP N +GYP
Sbjct: 95 TVVSTQR-SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDM--------INPVQ-QQNQIGYP 303 HSP 2 Score: 74.3294 bits (181), Expect = 7.364e-13 Identity = 48/180 (26.67%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAAS-SESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + FS G CK+I D P Y FV + A AL MNG+ + ++++ NWA P +K + V + S+ + ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATT-----PSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
BLAST of Nucleolysin TIA-1 isoform p40 vs. UniProt/SwissProt
Match: sp|Q01085|TIAR_HUMAN (Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1) HSP 1 Score: 219.164 bits (557), Expect = 1.519e-64 Identity = 99/219 (45.21%), Postives = 148/219 (67.58%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ---KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFS----IYINPVGY 1405
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FG++++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P + K L + +V SS NCT+Y GGI +GL ++L+R++F FG I+E+R+F EKGY+FVRF +HE A AI+ ++G + + KC WGKES D+ + Q + + +Y NP Y
Sbjct: 88 SQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQY 306 HSP 2 Score: 70.8626 bits (172), Expect = 7.180e-12 Identity = 48/189 (25.40%), Postives = 90/189 (47.62%), Query Frame = 2
Query: 773 IQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
+ ED ++VG+++ ++ + + FS G CK+I + + P Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W
Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 172
BLAST of Nucleolysin TIA-1 isoform p40 vs. UniProt/SwissProt
Match: sp|P70318|TIAR_MOUSE (Nucleolysin TIAR OS=Mus musculus OX=10090 GN=Tial1 PE=1 SV=1) HSP 1 Score: 219.164 bits (557), Expect = 2.415e-64 Identity = 99/219 (45.21%), Postives = 148/219 (67.58%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ---KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFS----IYINPVGY 1405
S ++DTSNH+H+FVGD++PEI T+ ++ F+ FG++++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P + K L + +V SS NCT+Y GGI +GL ++L+R++F FG I+E+R+F EKGY+FVRF +HE A AI+ ++G + + KC WGKES D+ + Q + + +Y NP Y
Sbjct: 105 SQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQY 323 HSP 2 Score: 62.7734 bits (151), Expect = 3.600e-9 Identity = 49/205 (23.90%), Postives = 90/205 (43.90%), Query Frame = 2
Query: 773 IQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDM----------------HTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
+ ED ++VG+++ ++ + + FS G CK+I + HT Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W
Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDP-YCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 189
BLAST of Nucleolysin TIA-1 isoform p40 vs. UniProt/SwissProt
Match: sp|Q9M427|UBP1_NICPL (Oligouridylate-binding protein 1 OS=Nicotiana plumbaginifolia OX=4092 GN=UBP1 PE=2 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 6.857e-31 Identity = 67/203 (33.00%), Postives = 112/203 (55.17%), Query Frame = 2
Query: 776 QEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESN----------------CTIYVGGITNGLCEELLRESFKEFGD--ILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKE 1330
+EDTSNHY+IFVGD++PE+ L FS++ ++ +++ D T + +G+GFV++ ++EA+ A+N +NGK+LG+RQIR NWA + ++ E+ + +S+ T+YVG + + L F G I +VRI ++KG+ FVR+ SH A +AI + + + + KCSWG +
Sbjct: 127 REDTSNHYNIFVGDLSPEVTDATLFACFSVYTSCSDARVMWDQKTGRSRGFGFVSFRNQQEAQSAINDLNGKWLGSRQIRCNWAAKGAGAVGEQNSDAKSVVELTSGTSDDGQEKVVNEDAPENNPQYTTVYVGNLAPEVTSVDLHRHFHALGAGVIEDVRIQRDKGFGFVRYSSHAEAARAIQLGNARLLFGKPVKCSWGSK 329 HSP 2 Score: 79.7221 bits (195), Expect = 1.276e-14 Identity = 56/222 (25.23%), Postives = 101/222 (45.50%), Query Frame = 2
Query: 734 LAPQNHAPIT--NISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF------KEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW--------GKESNDLKET 1351
LAP PI N+ D+S ++VG+I P++ L+E F+ G + CK+I+ + YGFV Y + A A+ +NG+ L + I+ NWA Y + ++ I+VG ++ + + L F + + R+ + +G+ FV F + + A AI ++GK +GS+ +C+W G++++D K
Sbjct: 26 LAPPQIEPILSGNLPPGFDSSTCRSVYVGNIHPQVTEPLLQEVFASTGPLEGCKLIR----KDKSSYGFVDYFDRRSAALAIVTLNGRHLFGQPIKVNWA----------------YASAQREDTSNHYNIFVGDLSPEVTDATLFACFSVYTSCSDARVMWDQKTGRSRGFGFVSFRNQQEAQSAINDLNGKWLGSRQIRCNWAAKGAGAVGEQNSDAKSV 227 HSP 3 Score: 63.929 bits (154), Expect = 1.553e-9 Identity = 35/135 (25.93%), Postives = 64/135 (47.41%), Query Frame = 2
Query: 674 KTVGELNRYQTHTLTIPQLTLAPQNHA--PITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPL 1072
K G + + ++ +LT + + N E+ + ++VG++APE+ + L F G +I+D+ Q+ KG+GFV Y++ EA A+ N + L + ++ +W + P PPG PL
Sbjct: 212 KGAGAVGEQNSDAKSVVELTSGTSDDGQEKVVNEDAPENNPQYTTVYVGNLAPEVTSVDLHRHFHALG----AGVIEDVRIQRDKGFGFVRYSSHAEAARAIQLGNARLLFGKPVKCSWGSK--PTPPGSSSNPL 340
BLAST of Nucleolysin TIA-1 isoform p40 vs. TrEMBL
Match: D5JG79 (TIA1-like protein OS=Dugesia japonica OX=6161 GN=TIA-1 PE=2 SV=1) HSP 1 Score: 768.459 bits (1983), Expect = 0.000e+0 Identity = 368/383 (96.08%), Postives = 373/383 (97.39%), Query Frame = 2
Query: 461 MWGDFMLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHPNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDL-STTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNGLINQFSTARGMNS 1606
MWGDFMLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAAN+IFAHPNH LLPALQAMTSGMQLNKYK GE+NRYQTHTLTIPQLTLAPQ HAPI NIS QEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQN ILNPFSIYINPVGYPYSLLTQQ+PDL +TTNYNVSLSNLHNLT PDF GYMMSSVPNGLTNSN+GALNGLINQFSTARGMNS
Sbjct: 1 MWGDFMLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANNIFAHPNHSLLPALQAMTSGMQLNKYKAFGEVNRYQTHTLTIPQLTLAPQTHAPINNISTQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNGILNPFSIYINPVGYPYSLLTQQIPDLNTTTNYNVSLSNLHNLTGPDFSGYMMSSVPNGLTNSNLGALNGLINQFSTARGMNS 383
BLAST of Nucleolysin TIA-1 isoform p40 vs. TrEMBL
Match: A0A267FP37 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005244g2 PE=4 SV=1) HSP 1 Score: 335.109 bits (858), Expect = 2.206e-106 Identity = 160/236 (67.80%), Postives = 187/236 (79.24%), Query Frame = 2
Query: 632 ALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESND 1339
+LQ +G+ LNK V TL L L+ QNH + DT++HYHIFVGD+APEIE+ L+E FS FG VTECKIIKDMHTQKPKGYGFVAYA +EEAEEA+ KMNG+ LG+R IRTNWA+R+PPQPP DQKPL+Y+EV A+S SNCT+YVGGIT GLCEELLRE+FK+FG+ILEVR+FKEKGYAFVRFD+HEGAT+AII MHGK+VG Q CKCSWGKESND
Sbjct: 68 SLQTALTGVPLNKGLQV---------TLPSAALALSTQNH--------KLDTTSHYHIFVGDLAPEIESHQLKEAFSAFGIVTECKIIKDMHTQKPKGYGFVAYANREEAEEAMQKMNGQLLGSRTIRTNWAVRKPPQPPA-DQKPLNYDEVAQAASNSNCTVYVGGITRGLCEELLREAFKDFGEILEVRVFKEKGYAFVRFDTHEGATKAIITMHGKDVGGQPCKCSWGKESND 285
BLAST of Nucleolysin TIA-1 isoform p40 vs. TrEMBL
Match: A0A267EXW9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006239g1 PE=4 SV=1) HSP 1 Score: 312.768 bits (800), Expect = 6.910e-98 Identity = 147/226 (65.04%), Postives = 178/226 (78.76%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIY----------INPVGYP 1408
T S + DT+ H+HIFVGD+AP++E+ L+E FS+FG VTECKIIKDMHTQKPKGYGFVA+A K EAE+A+ KMNG+ LG R IRTNWA+R+P Q P DQKPL+Y+EV ASS +N T+YVGGIT GLCEELLRE+FKEFG I+EVR+FKEKGYAF+RFD+HEGAT+AII MHGKEVG Q CKCSWGKESN+ + ++L P+S Y NP+ YP
Sbjct: 100 TGGSGKIDTTCHHHIFVGDLAPDVESHQLKEAFSVFGVVTECKIIKDMHTQKPKGYGFVAFANKNEAEDAMQKMNGQLLGNRAIRTNWAVRKPQQTP-VDQKPLNYDEVAQASSTANSTVYVGGITRGLCEELLREAFKEFGAIMEVRVFKEKGYAFIRFDTHEGATRAIITMHGKEVGGQPCKCSWGKESNE--KDGAATLLTPYSYYAAAAAAAAAAANPLAYP 322
BLAST of Nucleolysin TIA-1 isoform p40 vs. TrEMBL
Match: A0A1I8GJB9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 310.842 bits (795), Expect = 9.572e-98 Identity = 145/219 (66.21%), Postives = 175/219 (79.91%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIY----------INPVGYP 1408
DT+ H+HIFVGD+AP++E+ L+E FS+FG VTECKIIKDMHTQKPKGYGFVA+A K EAE+A+ KMNG+ LG R IRTNWA+R+P Q P DQKPL+Y+EV ASS +N T+YVGGIT GLCEELLRE+FKEFG I+EVR+FKEKGYAF+RFD+HEGAT+AII MHGKEVG Q CKCSWGKESN+ + ++L P+S Y NP+ YP
Sbjct: 97 DTTCHHHIFVGDLAPDVESHQLKEAFSVFGVVTECKIIKDMHTQKPKGYGFVAFANKNEAEDAMQKMNGQLLGNRAIRTNWAVRKPQQTP-VDQKPLNYDEVAQASSTANSTVYVGGITRGLCEELLREAFKEFGAIMEVRVFKEKGYAFIRFDTHEGATRAIITMHGKEVGGQPCKCSWGKESNE--KDGAATLLTPYSYYAAAAAAAAAAANPLAYP 312
BLAST of Nucleolysin TIA-1 isoform p40 vs. TrEMBL
Match: A0A1I8J4M4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 270.011 bits (689), Expect = 3.582e-83 Identity = 137/236 (58.05%), Postives = 161/236 (68.22%), Query Frame = 2
Query: 632 ALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESND 1339
+LQ+ +G+ LNK V TL L L+ QNH + DT++HYHIFVGD+APEIE+ L+E FS FG VTECKIIKDMHTQKPKGYGFVAYA +EEAEEA+ KMNG+ LG+R IRTNWA+R+PPQPP EELLRE+FK+FG+ILEVR+FKEKGYAFVRFD+HEGAT+AII MHGK+VG Q CKCSWGKESND
Sbjct: 68 SLQSALTGVPLNKGLQV---------TLPSAALALSTQNH--------KLDTTSHYHIFVGDLAPEIESHQLKEAFSAFGIVTECKIIKDMHTQKPKGYGFVAYANREEAEEAMQKMNGQLLGSRTIRTNWAVRKPPQPP---------------------------------EELLREAFKDFGEILEVRVFKEKGYAFVRFDTHEGATKAIITMHGKDVGGQPCKCSWGKESND 253
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Cavefish
Match: tia1l (TIA1 cytotoxic granule associated RNA binding protein [Source:NCBI gene;Acc:103030565]) HSP 1 Score: 231.106 bits (588), Expect = 1.767e-70 Identity = 98/200 (49.00%), Postives = 146/200 (73.00%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGK----DQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD++PEI T ++ F+ FG++++ +++KD+ T K KGYGF+++ K +AE A+ +MNG++LG RQIRTNWA R+PP P + K L Y EV + SS SNCT+Y GG+T+GL ++L+R++F FG I+E+R+F +KGY+FVRFDSHEGA AI+ ++G + KC WGKE+ D++ Q
Sbjct: 87 SQKKDTSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRKPPAPKSNYETGNTKHLSYEEVLSQSSPSNCTVYCGGVTSGLTDQLMRQTFSPFGQIMEIRVFPDKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGKETADMRAMQQ 286 HSP 2 Score: 70.0922 bits (170), Expect = 1.196e-12 Identity = 44/179 (24.58%), Postives = 85/179 (47.49%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + F+ G CK+I D P Y FV + A AL MNG+ + + ++ NWA P KD + ++ ++VG ++ + + ++ +F FG I + R+ K+ KGY F+ F + A AI +M+G+ +G + + +W
Sbjct: 10 LYVGNLSRDVTEALILQVFTQIGPCKSCKMIIDTAGNDP--YCFVEFYEHMHAAAALGAMNGRKILGKDMKVNWASM--PSSQKKD-------------TSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNW 171
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Cavefish
Match: tia1l (TIA1 cytotoxic granule associated RNA binding protein [Source:NCBI gene;Acc:103030565]) HSP 1 Score: 231.106 bits (588), Expect = 1.767e-70 Identity = 98/200 (49.00%), Postives = 146/200 (73.00%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGK----DQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD++PEI T ++ F+ FG++++ +++KD+ T K KGYGF+++ K +AE A+ +MNG++LG RQIRTNWA R+PP P + K L Y EV + SS SNCT+Y GG+T+GL ++L+R++F FG I+E+R+F +KGY+FVRFDSHEGA AI+ ++G + KC WGKE+ D++ Q
Sbjct: 87 SQKKDTSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRKPPAPKSNYETGNTKHLSYEEVLSQSSPSNCTVYCGGVTSGLTDQLMRQTFSPFGQIMEIRVFPDKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGKETADMRAMQQ 286 HSP 2 Score: 70.0922 bits (170), Expect = 1.196e-12 Identity = 44/179 (24.58%), Postives = 85/179 (47.49%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + F+ G CK+I D P Y FV + A AL MNG+ + + ++ NWA P KD + ++ ++VG ++ + + ++ +F FG I + R+ K+ KGY F+ F + A AI +M+G+ +G + + +W
Sbjct: 10 LYVGNLSRDVTEALILQVFTQIGPCKSCKMIIDTAGNDP--YCFVEFYEHMHAAAALGAMNGRKILGKDMKVNWASM--PSSQKKD-------------TSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNW 171
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Cavefish
Match: tial1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:NCBI gene;Acc:103030475]) HSP 1 Score: 218.009 bits (554), Expect = 5.600e-65 Identity = 98/206 (47.57%), Postives = 140/206 (67.96%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG----------KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD++PEI T +R F+ FG++++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P K L + +V SS NCT+Y GGI +GL E L+R++F FG I+E+R+F EKGY+F+RF SHE A AI+ ++G + S + KC WGKES D+ ++ Q
Sbjct: 87 SQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDSKQIAHLGSSKQLRFEDVVNQSSPQNCTVYCGGIQSGLSEHLIRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIESHIVKCYWGKESPDMAKSVQ 292 HSP 2 Score: 70.8626 bits (172), Expect = 9.883e-13 Identity = 49/201 (24.38%), Postives = 95/201 (47.26%), Query Frame = 2
Query: 779 EDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNS 1363
ED + ++VG+++ ++ + + F+ G CK+I + + P Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG ++ + + +R +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W ++ Q+S
Sbjct: 2 EDDCHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEHTSNDP--YCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDS 185
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Cavefish
Match: tia1l (TIA1 cytotoxic granule associated RNA binding protein [Source:NCBI gene;Acc:103030565]) HSP 1 Score: 190.66 bits (483), Expect = 1.418e-55 Identity = 80/159 (50.31%), Postives = 121/159 (76.10%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVR 1237
S ++DTSNH+H+FVGD++PEI T ++ F+ FG++++ +++KD+ T K KGYGF+++ K +AE A+ +MNG++LG RQIRTNWA R+PP P + K L Y EV + SS SNCT+Y GG+T+GL ++L+R++F FG I+E+R+F +KGY+FVR
Sbjct: 86 SQKKDTSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRKPPAPKSNYESNTKHLSYEEVLSQSSPSNCTVYCGGVTSGLTDQLMRQTFSPFGQIMEIRVFPDKGYSFVR 244 HSP 2 Score: 71.2478 bits (173), Expect = 3.687e-13 Identity = 44/180 (24.44%), Postives = 85/180 (47.22%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWG 1324
++VG+++ ++ + + F+ G CK+I D P Y FV + A AL MNG+ + + ++ NWA P KD + ++ ++VG ++ + + ++ +F FG I + R+ K+ KGY F+ F + A AI +M+G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEALILQVFTQIGPCKSCKMIIDTAGNDP--YCFVEFYEHMHAAAALGAMNGRKILGKDMKVNWASM--PSSQKKD-------------TSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWA 171
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Cavefish
Match: pabpc1b (poly(A) binding protein cytoplasmic 1 [Source:NCBI gene;Acc:103023186]) HSP 1 Score: 95.5153 bits (236), Expect = 2.911e-20 Identity = 51/175 (29.14%), Postives = 91/175 (52.00%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF-----KEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLC 1309
+IF+ ++ I+ + L + FS FG + CK++ D + K GYGFV + T+E AE A+ KMNG L R++ G+ + + A ++ +Y+ + +E L+E F ++G+ + +R+ K +G+ FV F+ HE A +A+ M+GKE+ +L
Sbjct: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSK--GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV-----------GRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDEKLKEVFSKYGNSMSIRVMTDDSGKSRGFGFVSFERHEDAQKAVDEMNGKELNGKLI 261 HSP 2 Score: 82.4185 bits (202), Expect = 4.395e-16 Identity = 56/221 (25.34%), Postives = 108/221 (48.87%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCT------IYVGGITNGLCEELLRESFKEFGDILEVRIF----KEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYI-------NPVGYPY 1411
++++ + +++ + L+E FS +G +++ D + K +G+GFV++ E+A++A+++MNGK L + I A + K ++ + F + T +YV + +G+ +E LR+ F FG I ++ + KG+ FV F S E AT+A+ M+G+ V ++ + + KE Q + N + + NPV PY
Sbjct: 192 NVYIKNFGEDMDDEKLKEVFSKYGNSMSIRVMTD-DSGKSRGFGFVSFERHEDAQKAVDEMNGKELNGKLIYVGRAQK-------KVERQTELKRKFEQMKQDRMTRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMDGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR----KEERQAHLTNQYMQRMASVRAVPNPVLNPY 400 HSP 3 Score: 80.4925 bits (197), Expect = 1.796e-15 Identity = 44/165 (26.67%), Postives = 80/165 (48.48%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE----KGYAFVRFDSHEGATQAIIRMHG 1285
++VGD+ ++ L E+FS G + ++ +DM T++ GY +V + +AE AL+ MN + R +R W+ R P + I++ + + + L ++F FG+IL ++ + KGY FV F++ E A +AI +M+G
Sbjct: 13 LYVGDLHQDVTEAMLYEKFSPAGAILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGRPVRIMWSQRDP-----------------SLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160 HSP 4 Score: 56.6102 bits (135), Expect = 5.711e-8 Identity = 28/91 (30.77%), Postives = 54/91 (59.34%), Query Frame = 2
Query: 773 IQEDTSNHYH---IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRR 1036
+++D Y ++V ++ I+ + LR+ FS FG +T K++ M + KG+GFV +++ EEA +A+ +MNG+ + T+ + A R+
Sbjct: 283 MKQDRMTRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVM--MDGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRK 371
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Sea Lamprey
Match: tia1l (cytotoxic granule-associated RNA binding protein 1, like [Source:ZFIN;Acc:ZDB-GENE-030131-2167]) HSP 1 Score: 218.009 bits (554), Expect = 2.534e-67 Identity = 102/218 (46.79%), Postives = 144/218 (66.06%), Query Frame = 2
Query: 791 NHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGK---DQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLP 1435
+HYH+FVGD++PEI T LR F+ FG++++ +++KD+ T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+PP P G D K L + EV SS +NCT+Y GGIT GL E+L+R++F FG ILE+R+F +KGY+F+RF +HE A AI+ ++G + KC WGKE++D +N F + VGY TQ P
Sbjct: 1 DHYHVFVGDLSPEISTDDLRAAFAPFGKISDARVVKDLATGKSKGYGFVSFFQKLDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKGSQDTDPKHLSFEEVLNQSSPTNCTVYCGGITQGLTEQLMRQTFLLFGQILEIRVFPDKGYSFIRFATHESAAHAIVSVNGSTIEGFSVKCFWGKEASDP--------VNQFQQQFSQVGYTQQPWTQWGP 210
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Sea Lamprey
Match: pabpc4 (poly(A) binding protein, cytoplasmic 4 (inducible form) [Source:ZFIN;Acc:ZDB-GENE-030131-9663]) HSP 1 Score: 92.0485 bits (227), Expect = 7.155e-20 Identity = 50/170 (29.41%), Postives = 89/170 (52.35%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF-----KEKGYAFVRFDSHEGATQAIIRMHGKEV 1294
++F+ ++ I+ + + + FS FG + CK++ D + +GYGFV + T+E A+ A+ KMNG L R R + G+ + + + A ++ +Y+ + + E+ LRE F +FG L V + K +G+ FV F+ HE A +A+ M+GKE+
Sbjct: 100 NVFIKNLDKSIDNKAMYDTFSAFGNILSCKVVCDENGS--RGYGFVHFETQEAADRAIEKMNGMLLNDRLARRRFV--------GRFKSRKEREQEMGARAKEFTNVYIKNFGDDMDEDKLREFFGKFGKALSVCVMSDECGKSRGFGFVSFEQHEDAQRAVNEMNGKEL 259 HSP 2 Score: 82.0333 bits (201), Expect = 9.109e-17 Identity = 54/190 (28.42%), Postives = 94/190 (49.47%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYN-EVFAA---SSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE----KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLK 1345
++++ + +++ LRE F FG+ ++ D K +G+GFV++ E+A+ A+N+MNGK L R + A Q G+ Q L E+ S +YV + + + +E LR+ F +G I ++ E KG+ FV F S E AT+A+ M+G+ VGS+ + + + K
Sbjct: 195 NVYIKNFGDDMDEDKLREFFGKFGKALSVCVMSD-ECGKSRGFGFVSFEQHEDAQRAVNEMNGKELNGRTVFVGRA-----QKKGERQAELKRKFEMLKQERISRYQGVNLYVKNLDDNIDDEQLRKEFAPYGTITSTKVMSEEGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERK 378 HSP 3 Score: 81.6481 bits (200), Expect = 1.294e-16 Identity = 47/189 (24.87%), Postives = 89/189 (47.09%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE----KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
++VGD+ P++ L E+FS G V ++ +DM T++ GY +V + +AE AL+ MN + + IR W+ R P + +++ + + + + ++F FG+IL ++ + +GY FV F++ E A +AI +M+G + +L + + KE Q
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDP-----------------SLRKSGVGNVFIKNLDKSIDNKAMYDTFSAFGNILSCKVVCDENGSRGYGFVHFETQEAADRAIEKMNGMLLNDRLARRRFVGRFKSRKEREQ 184
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030]) HSP 1 Score: 76.6406 bits (187), Expect = 3.271e-16 Identity = 51/183 (27.87%), Postives = 85/183 (46.45%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQ-PPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF------KEKGYAFVRFDSHEGATQAIIRM------HGKEVGSQLCK 1312
+F+G ++ E +R+ F +G +T+C +++D HT++ +G+GFV Y EE + A++ L R + AI R PG K I+VGGI + E+ LRE F+ +GD+ + K++G+ FV F H+ + I++ H EV L K
Sbjct: 11 LFIGGLSFETTEDSMRKHFEQWGTLTDCVVMRDPHTKRSRGFGFVTYTCPEEVDAAMD-ARPHHLDNRVVEAKRAISREDSLKPGAHLKVK--------------KIFVGGIRDDTDEQHLREYFQVYGDVEAAEVMEDRSTGKKRGFGFVTFSDHDTVDKVIVQKYHTINGHKAEVRKALSK 178
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030]) HSP 1 Score: 77.0258 bits (188), Expect = 1.794e-15 Identity = 54/202 (26.73%), Postives = 100/202 (49.50%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFG-----DILEVR-IFKEKGYAFVRFDSHEGATQAIIRM------HGKEVGSQLCKCSWGKESNDLKETSQNSILN 1372
+F+G ++ E + +++ F +G +T+C +++D HT++ +G+GFV Y + EE + A+ ++ L R + AI R KP + +V I+VGGI + E+ LR+ F E+G D++E R K++G+ FV F H+ + +++ H EV L K D ++ +NS+ +
Sbjct: 35 LFIGGLSFETTEESMQKHFEQWGTLTDCVVMRDPHTKRSRGFGFVTYMSAEEVDAAM-EVRPHHLDGRVVEAKRAISREDS-----LKPGAHLKV--------KKIFVGGIKDNTDEDHLRDYFSEYGMVESVDVMEDRQSGKKRGFGFVTFSDHDAVDKVVVQKYHTINGHKAEVRKALSKQEMNSLGGDPRQ-GENSVFS 221
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004893.1 (pep scaffold:Pmarinus_7.0:GL479484:4:2056:-1 gene:ENSPMAG00000004449.1 transcript:ENSPMAT00000004893.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 72.4034 bits (176), Expect = 1.212e-14 Identity = 46/167 (27.54%), Postives = 87/167 (52.10%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAI-RRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF------KEKGYAFVRFDSHEGATQAIIRMH 1282
+FVG ++ E + LR+ F +G +T+C ++KD +++ +G+GFV +++ E + A++ K G R + A+ R PG + S I+VGGI + EE LR+ F+++G I V + K++G+AFV F+ H+ + +++ +
Sbjct: 13 LFVGGLSFETTEEGLRQYFEQWGSLTDCVVMKDTQSKRSRGFGFVTFSSMSEVDAAMSARPHKIDG-RMVEPKRAVSREDSMRPG--------------AHLSVKKIFVGGIKDDTDEEHLRDYFEKYGRIEIVEVMTERESGKKRGFAFVTFNDHDPVDKIVVQKY 164
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Yeast
Match: NAM8 (RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function [Source:SGD;Acc:S000001128]) HSP 1 Score: 83.5741 bits (205), Expect = 1.918e-17 Identity = 57/228 (25.00%), Postives = 96/228 (42.11%), Query Frame = 2
Query: 785 TSNHYHIFVGDIAPEI-ETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGK---------------DQKPLDYNEVFAASSE-----------------------------SNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKES 1333
+ N+ IFVGD+AP + E+Q + + + KI+ D T KGYGFV + +E + AL++M G FL R I+ + G D + L + F ++ +N T+++GG+++ + E+ LR F+ FG I+ V+I K FV++ A AI M G + + + SWG+ +
Sbjct: 159 SGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSA 386
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Yeast
Match: PUB1 (Poly (A)+ RNA-binding protein; abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; implicated in regulation of translation; carries Q/N-rich domain at C- terminus, identified as candidate prion; human homolog Tia1 is critical for normal synaptic plasticity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004961]) HSP 1 Score: 75.485 bits (184), Expect = 5.289e-15 Identity = 49/200 (24.50%), Postives = 91/200 (45.50%), Query Frame = 2
Query: 755 PITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDIL------EVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESN 1336
P I+ +TS+ ++VG++ I L++ F + G + KI+ D + K Y FV Y +A AL +NGK + ++ NWA + +SS+ ++VG + + +E LR +FK+F L +++ +GY FV F S + A A+ M G+++ + + +W + +
Sbjct: 62 PANAITGGRETSDRV-LYVGNLDKAITEDILKQYFQVGGPIANIKIMIDKNN-KNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQSQ-----------------QSSSDDTFNLFVGDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDDAQNAMDSMQGQDLNGRPLRINWAAKRD 242 HSP 2 Score: 50.0618 bits (118), Expect = 5.860e-7 Identity = 27/99 (27.27%), Postives = 50/99 (50.51%), Query Frame = 2
Query: 1046 PPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL 1342
PP + + +D+ + ++ T Y+G I + E L F+ FG IL+ + + EKG F+++D+HE A I+ + + + WGKE ++
Sbjct: 321 PPQVNPQAVDH--IIRSAPPRVTTAYIGNIPHFATEADLIPLFQNFGFILDFKHYPEKGCCFIKYDTHEQAAVCIVALANFPFQGRNLRTGWGKERSNF 417 HSP 3 Score: 49.2914 bits (116), Expect = 1.238e-6 Identity = 26/105 (24.76%), Postives = 53/105 (50.48%), Query Frame = 2
Query: 1079 NEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKG-----YAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPF 1378
N + S+ +YVG + + E++L++ F+ G I ++I +K YAFV + A A+ ++GK++ + + K +W +S +++S + N F
Sbjct: 64 NAITGGRETSDRVLYVGNLDKAITEDILKQYFQVGGPIANIKIMIDKNNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQS---QQSSSDDTFNLF 165
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Yeast
Match: NSR1 (Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation [Source:SGD;Acc:S000003391]) HSP 1 Score: 74.7146 bits (182), Expect = 8.249e-15 Identity = 46/187 (24.60%), Postives = 98/187 (52.41%), Query Frame = 2
Query: 779 EDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRI------FKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
E+T IFVG ++ I+ ++L++ F G V ++I + T + +GYG+V + K AE+A+ +M GK + R I + + + P G + + + + SE + T+++G ++ + + E F + G+++ VRI + KG+ +V+F + E A +A+ + G+ + ++ + +
Sbjct: 162 EETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSK---PAGNNDRAKKFGDT---PSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDF 342 HSP 2 Score: 50.8322 bits (120), Expect = 3.597e-7 Identity = 22/79 (27.85%), Postives = 49/79 (62.03%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRP 1039
+F+G+++ + + E F+ G V +I T++PKG+G+V ++ E+A++AL+ + G+++ R +R +++ RP
Sbjct: 269 LFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFSSPRP 347
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Yeast
Match: PAB1 (Poly(A) binding protein; part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex [Source:SGD;Acc:S000000967]) HSP 1 Score: 74.7146 bits (182), Expect = 1.439e-14 Identity = 47/185 (25.41%), Postives = 90/185 (48.65%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE-----KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESND 1339
+IF+ ++ P+I+ + L + FS+FG + KI D K KG+GFV + + A+EA++ +NG L ++I + R + ++ Y +YV I + +E +E F +FG I+ + K+ KG+ FV ++ HE A +A+ ++ E+ + ++ N+
Sbjct: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHY-----------TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNE 299 HSP 2 Score: 65.0846 bits (157), Expect = 1.589e-11 Identity = 41/166 (24.70%), Postives = 75/166 (45.18%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF-----KEKGYAFVRFDSHEGATQAIIRMHG 1285
++VGD+ P + L + FS G V+ ++ +D T+ GY +V + E +A+ ++N + R R W+ R P + + + I++ + + + L ++F FGDIL +I K KG+ FV F+ A +AI ++G
Sbjct: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDP-----------------SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNG 188 HSP 3 Score: 48.9062 bits (115), Expect = 1.519e-6 Identity = 23/94 (24.47%), Postives = 47/94 (50.00%), Query Frame = 2
Query: 1106 SNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEK------GYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSIL 1369
S+ ++YVG + + E L + F G + +R+ ++ GYA+V F+ HE +AI +++ + +LC+ W + L++ +I
Sbjct: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIF 129 HSP 4 Score: 46.595 bits (109), Expect = 9.712e-6 Identity = 22/79 (27.85%), Postives = 46/79 (58.23%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRR 1036
++FV ++ ++ + L E F+ +G +T K+++ K KG+GFV ++T EEA +A+ + N + + + + A R+
Sbjct: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMR-TENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRK 400
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Yeast
Match: NGR1 (RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase [Source:SGD;Acc:S000000416]) HSP 1 Score: 59.3066 bits (142), Expect = 1.100e-9 Identity = 31/82 (37.80%), Postives = 43/82 (52.44%), Query Frame = 2
Query: 1106 SNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKET 1351
+N T++VGG+ E LR FK FG IL VRI K FV+F+ A +I + G VG + SWG+ S+ +T
Sbjct: 358 TNTTVFVGGLVPKTTEFQLRSLFKPFGPILNVRIPNGKNCGFVKFEKRIDAEASIQGLQGFIVGGSPIRLSWGRPSSSNAKT 439
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Nematostella
Match: EDO32492 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUY1]) HSP 1 Score: 135.961 bits (341), Expect = 1.280e-36 Identity = 61/154 (39.61%), Postives = 103/154 (66.88%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRR--PPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVR 1237
DT+NH+HIFVGD+A ++ LR+ F FG ++E +++KD K KG+GFV++ +E+A +A+ +M+ +G +Q++TNWA R+ P Q K L +++VF SS+ N T+YVG + + + L++ F ++G ILE ++F +KGYAF++
Sbjct: 82 DTNNHFHIFVGDLAENVDNALLRKTFEPFGEISEVRVVKDPAKNKSKGFGFVSFVRREDAAKAIAEMDSVTIGGKQVKTNWAARKNNPTQSKYVCVKNLLWDDVFHQSSQLNTTVYVGNLPPDVKDYELQQMFSQYGSILETKVFADKGYAFIK 235 HSP 2 Score: 88.1965 bits (217), Expect = 8.216e-20 Identity = 53/184 (28.80%), Postives = 90/184 (48.91%), Query Frame = 2
Query: 806 FVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESND 1339
+VG++ P+ + + F+ +V CK+I + + P Y FV + T +A+EA +M+ + + ++++ NWA P G D N F I+VG + + LLR++F+ FG+I EVR+ K+ KG+ FV F E A +AI M +G + K +W N+
Sbjct: 1 YVGNLDPKCTQELICSIFNKIAKVVRCKMINSVSYKGP--YCFVEFETHADAQEAKFRMDQRTVMDKKLKVNWATNHPGMKRG------DTNNHFH--------IFVGDLAENVDNALLRKTFEPFGEISEVRVVKDPAKNKSKGFGFVSFVRREDAAKAIAEMDSVTIGGKQVKTNWAARKNN 168
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Nematostella
Match: EDO33206 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSV8]) HSP 1 Score: 86.6557 bits (213), Expect = 7.367e-18 Identity = 72/278 (25.90%), Postives = 129/278 (46.40%), Query Frame = 2
Query: 476 MLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAH--PNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE-----KGYAFVRFDSHEGATQAIIRMHGK 1288
+ + NL K +DN S T +A G + + N F H L A+ A GM LN K + R+ + I ++ P+ TN+ +V + +++ + ++E + G++ K++ D K KG+GFV++ T EEAEEA+N +NGK +G R++ A +R + + + ++ + +Y+ + + + +E LRE F +G I ++ K+ KG+ FV F S E AT+A+ M+G+
Sbjct: 103 IFIKNLDKSIDNKSLYDTFSAFGNILSCKIAQDELGNPKGYGFVHFETEDAALEAI-ARVDGMLLNDKKVF--VGRWMSKKERIEKMGTQPKK---FTNV------------YVKNFGDDMDDEQMKEICAEAGKIVSLKVMTDPEG-KSKGFGFVSFETPEEAEEAVNVLNGKEIGGRRLWAGRAKKRAER-AAEVKAEIEKKRQERINRFQGVNLYIKNLDDPIDDERLREEFSPYGTISSAKVMKDDKGNSKGFGFVCFSSPEEATKAVTEMNGR 360 HSP 2 Score: 79.337 bits (194), Expect = 1.560e-15 Identity = 46/166 (27.71%), Postives = 80/166 (48.19%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE-----KGYAFVRFDSHEGATQAIIRMHG 1285
++VGD+AP++ L E+FS G V ++ +D+ T++ GY +V + AE+AL+ MN + R R W R P + I++ + + + L ++F FG+IL +I ++ KGY FV F++ + A +AI R+ G
Sbjct: 15 LYVGDLAPDVTEAMLYEKFSTAGSVLSIRVCRDLVTRRSLGYAYVNFQQPGHAEKALDTMNFDPIKGRPCRIMWQQRDP-----------------SLRKSGVGNIFIKNLDKSIDNKSLYDTFSAFGNILSCKIAQDELGNPKGYGFVHFETEDAALEAIARVDG 163 HSP 3 Score: 78.9518 bits (193), Expect = 1.811e-15 Identity = 47/174 (27.01%), Postives = 89/174 (51.15%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRT-NWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIF-----KEKGYAFVRFDSHEGATQAIIRMHGKEVGSQ 1303
+IF+ ++ I+ + L + FS FG + CKI +D PKGYGFV + T++ A EA+ +++G L +++ W ++ + E + +YV + + +E ++E E G I+ +++ K KG+ FV F++ E A +A+ ++GKE+G +
Sbjct: 102 NIFIKNLDKSIDNKSLYDTFSAFGNILSCKIAQD-ELGNPKGYGFVHFETEDAALEAIARVDGMLLNDKKVFVGRWMSKK------------ERIEKMGTQPKKFTNVYVKNFGDDMDDEQMKEICAEAGKIVSLKVMTDPEGKSKGFGFVSFETPEEAEEAVNVLNGKEIGGR 262 HSP 4 Score: 54.6842 bits (130), Expect = 6.930e-8 Identity = 26/79 (32.91%), Postives = 50/79 (63.29%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRR 1036
++++ ++ I+ + LRE FS +G ++ K++KD KG+GFV +++ EEA +A+ +MNG+ L ++ + A RR
Sbjct: 298 NLYIKNLDDPIDDERLREEFSPYGTISSAKVMKD-DKGNSKGFGFVCFSSPEEATKAVTEMNGRILISKPLYVALAQRR 375
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Nematostella
Match: EDO46306 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQK4]) HSP 1 Score: 79.7221 bits (195), Expect = 7.605e-16 Identity = 52/178 (29.21%), Postives = 85/178 (47.75%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKC 1315
++VG I E+ + +R F FG + + + D K KG+ FV Y E A+ AL +MNG LG R I+ + RP P PL E F ++ IY+ + L E+ ++ F+ FG ++ + KE KGY F+ +++ + A AI M+ ++G Q +
Sbjct: 65 RVYVGSINFELREEHIRTAFHPFGPINKIDLSWDPLNMKHKGFAFVEYDLPEAAQLALEQMNGVLLGGRNIK----VGRPSNVP--QAAPL--IEQFEQEAKKYARIYIASVHPDLLEDDIKSVFEAFGKVVHCSLSKEPMTGKHKGYGFIEYENQQSANDAIASMNLFDLGGQFLRV 234 HSP 2 Score: 55.8398 bits (133), Expect = 2.628e-8 Identity = 26/88 (29.55%), Postives = 47/88 (53.41%), Query Frame = 2
Query: 776 QEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRP 1039
+++ + I++ + P++ ++ F FG+V C + K+ T K KGYGF+ Y ++ A +A+ MN LG + +R AI P
Sbjct: 154 EQEAKKYARIYIASVHPDLLEDDIKSVFEAFGKVVHCSLSKEPMTGKHKGYGFIEYENQQSANDAIASMNLFDLGGQFLRVGRAITPP 241
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Nematostella
Match: EDO34879 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN30]) HSP 1 Score: 78.1814 bits (191), Expect = 8.744e-16 Identity = 45/170 (26.47%), Postives = 83/170 (48.82%), Query Frame = 2
Query: 800 HIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE-----KGYAFVRFDSHEGATQAIIRMHGKEV 1294
++ + + P + + +++ F G VT CK+I+D T + GY FV Y ++A +A+ +MNG L + ++ ++A RP +++ N +Y+ G+ + EE + FK FG I+ ++ K+ +G FVRFD A AI ++ K +
Sbjct: 11 NLIINYVPPSMSQEDIKKIFGTVGNVTSCKLIRDRATGQSLGYAFVNYDNPDDANKAVREMNGARLQNKTLKVSFA--RP-----------------SSTEIKNANLYISGLPKDMKEEEVEALFKPFGKIITSKVLKDVSGEGRGTGFVRFDKRCEAQTAIDDLNNKTL 161
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Nematostella
Match: EDO39989 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8H9]) HSP 1 Score: 63.1586 bits (152), Expect = 4.027e-12 Identity = 28/91 (30.77%), Postives = 52/91 (57.14%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQI---RTNWAIR 1033
S+ + N + IF GD+ E+ + L F+ + + KI++D + K KGYGFV++ + +A+ +MNGK++G+R + ++ W R
Sbjct: 18 SLAQWDPNDFRIFCGDLGSEVTDESLTRAFAKYTSFLKAKIVRDKKSNKSKGYGFVSFKDPNDFIKAMREMNGKYIGSRPVKLRKSTWKDR 108
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Medaka
Match: ENSORLT00000019582.2 (nucleolysin TIA-1 [Source:NCBI gene;Acc:101158614]) HSP 1 Score: 229.95 bits (585), Expect = 2.282e-69 Identity = 103/225 (45.78%), Postives = 152/225 (67.56%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQ 1426
T S ++DTSNH+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P + K L + EV + SS SNCT+Y GG+++GL E+L+R++F FG I+EVR+F +KGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+ + Q + + P PY Q
Sbjct: 83 TPTSQKKDTSNHFHVFVGDLSPEITTEDVKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQHMGGQWLGGRQIRTNWATRKPPAPKTTYESNSKHLSFEEVMSQSSPSNCTVYCGGVSSGLTEQLMRQTFSAFGQIMEVRVFPDKGYSFVRFNSHESAAHAIVSVNGTSIDGHVVKCYWGKETPDMMNSMQQMSIPQQNKIGFPAAQPYGQWGQ 307 HSP 2 Score: 72.0182 bits (175), Expect = 4.064e-13 Identity = 45/179 (25.14%), Postives = 84/179 (46.93%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSW 1321
++VG+++ ++ + + F+ G CK+I D P Y FV + A +L MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI M G+ +G + + +W
Sbjct: 9 LYVGNLSRDVTEPLILQVFTQIGPCKSCKMIVDTAGNDP--YCFVEFYDHRHAAASLAAMNGRKIMGKEVKVNWATT--PTSQKKD-------------TSNHFHVFVGDLSPEITTEDVKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQHMGGQWLGGRQIRTNW 170
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Medaka
Match: ENSORLT00000003147.2 (nucleolysin TIA-1 [Source:NCBI gene;Acc:101155125]) HSP 1 Score: 221.861 bits (564), Expect = 2.632e-66 Identity = 96/197 (48.73%), Postives = 144/197 (73.10%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRP-PQPPGK--DQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDL 1342
T S ++DTS+H+H+FVGD++PEI T ++ F+ FG++++C+++KDM T K KGYGFV++ K +AE A+ +M G++LG RQIRTNWA R+P P+ + K L ++EV SS SNCT+Y GG+T GL E+++R++F FG I+E+R+F EKGY+FVRF+SHE A AI+ ++G + + KC WGKE+ D+
Sbjct: 83 TPTSQKKDTSSHFHVFVGDLSPEITTDDIKAAFAPFGKISDCRVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPAPKTTNESSSSKQLSFDEVVNQSSPSNCTVYCGGVTTGLTEQIMRQTFSPFGQIMEIRVFPEKGYSFVRFNSHEAAAHAIVSVNGTSIEGYVVKCYWGKETTDM 279 HSP 2 Score: 72.7886 bits (177), Expect = 2.268e-13 Identity = 48/193 (24.87%), Postives = 89/193 (46.11%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNS 1363
++VG+++ ++ + E F G CK+I D P Y FV + A + MNG+ + ++++ NWA P KD + S+ ++VG ++ + + ++ +F FG I + R+ K+ KGY FV F + A AI +M G+ +G + + +W K T+++S
Sbjct: 9 LYVGNLSRDVTEALILELFGQIGPCKSCKMIVDTAGHDP--YCFVEFYEHRHATATIAAMNGRKILGKEVKVNWATT--PTSQKKD-------------TSSHFHVFVGDLSPEITTDDIKAAFAPFGKISDCRVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPAPKTTNESS 184
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Medaka
Match: tial1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:NCBI gene;Acc:101155294]) HSP 1 Score: 212.616 bits (540), Expect = 6.324e-63 Identity = 94/199 (47.24%), Postives = 136/199 (68.34%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ---KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD+ P+I T+ +R F+ FG++++ +++KD+ T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P K L + EV SS NCT+Y GGI + L E L+R++F FG I+E+R+F EKGY+F+RF SH+ A AI+ ++G + KC WGKES D+ + Q
Sbjct: 87 SQKKDTSNHFHVFVGDLNPDISTEDVRAAFTPFGKISDARVVKDLTTGKSKGYGFVSFYNKLDAENAIVHMAGQWLGGRQIRTNWATRKPPAPKSLQDSVSKQLRFEEVVTQSSPQNCTVYCGGIQSELSEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHDSAAHAIVSVNGTSIEGHAVKCYWGKESTDMAKNPQ 285 HSP 2 Score: 72.0182 bits (175), Expect = 4.367e-13 Identity = 50/202 (24.75%), Postives = 96/202 (47.52%), Query Frame = 2
Query: 779 EDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSI 1366
+D S+ ++VG+++ ++ + + F+ G CK+I + + P Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG + + E +R +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W ++ Q+S+
Sbjct: 2 DDESHPRTLYVGNLSRDVTEILILQLFTQIGPCKSCKMITEHTSNDP--YCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLNPDISTEDVRAAFTPFGKISDARVVKDLTTGKSKGYGFVSFYNKLDAENAIVHMAGQWLGGRQIRTNWATRKPPAPKSLQDSV 186
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Medaka
Match: tial1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:NCBI gene;Acc:101155294]) HSP 1 Score: 212.616 bits (540), Expect = 8.352e-63 Identity = 94/199 (47.24%), Postives = 136/199 (68.34%), Query Frame = 2
Query: 770 SIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ---KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQ 1357
S ++DTSNH+H+FVGD+ P+I T+ +R F+ FG++++ +++KD+ T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P K L + EV SS NCT+Y GGI + L E L+R++F FG I+E+R+F EKGY+F+RF SH+ A AI+ ++G + KC WGKES D+ + Q
Sbjct: 102 SQKKDTSNHFHVFVGDLNPDISTEDVRAAFTPFGKISDARVVKDLTTGKSKGYGFVSFYNKLDAENAIVHMAGQWLGGRQIRTNWATRKPPAPKSLQDSVSKQLRFEEVVTQSSPQNCTVYCGGIQSELSEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHDSAAHAIVSVNGTSIEGHAVKCYWGKESTDMAKNPQ 300 HSP 2 Score: 65.0846 bits (157), Expect = 8.157e-11 Identity = 51/216 (23.61%), Postives = 97/216 (44.91%), Query Frame = 2
Query: 779 EDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDM--------------HTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSI 1366
+D S+ ++VG+++ ++ + + F+ G CK+I ++ HT Y FV + +A AL MNG+ + ++++ NWA P KD + ++ ++VG + + E +R +F FG I + R+ K+ KGY FV F + A AI+ M G+ +G + + +W ++ Q+S+
Sbjct: 2 DDESHPRTLYVGNLSRDVTEILILQLFTQIGPCKSCKMITEVPIFVNRWGSSFFLQHTSNDP-YCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATT--PSSQKKD-------------TSNHFHVFVGDLNPDISTEDVRAAFTPFGKISDARVVKDLTTGKSKGYGFVSFYNKLDAENAIVHMAGQWLGGRQIRTNWATRKPPAPKSLQDSV 201
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Medaka
Match: ENSORLT00000019586.2 (nucleolysin TIA-1 [Source:NCBI gene;Acc:101158614]) HSP 1 Score: 191.815 bits (486), Expect = 2.621e-56 Identity = 86/184 (46.74%), Postives = 130/184 (70.65%), Query Frame = 2
Query: 761 TNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPG---KDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQ 1303
T S ++DTSNH+H+FVGD++PEI T+ ++ F+ FGR+++ +++KDM T K KGYGFV++ K +AE A+ M G++LG RQIRTNWA R+PP P + K L + EV + SS SNCT+Y GG+++GL E+L+R++F FG I+EVR+F +KGY+FV S+ G + ++G + +Q
Sbjct: 83 TPTSQKKDTSNHFHVFVGDLSPEITTEDVKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQHMGGQWLGGRQIRTNWATRKPPAPKTTYESNSKHLSFEEVMSQSSPSNCTVYCGGVSSGLTEQLMRQTFSAFGQIMEVRVFPDKGYSFVSAISNGGVMEPTQGLNGSMLANQ 266 HSP 2 Score: 72.4034 bits (176), Expect = 1.062e-13 Identity = 69/281 (24.56%), Postives = 120/281 (42.70%), Query Frame = 2
Query: 803 IFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKE------KGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGK----------ESN----DLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNG--LINQ 1579
++VG+++ ++ + + F+ G CK+I D P Y FV + A +L MNG+ + ++++ NWA P KD + ++ ++VG ++ + E ++ +F FG I + R+ K+ KGY FV F + A AI M G+ +G + + +W ESN +E S + ++Y V S LT+QL + + + + PD G +S++ NG LNG L NQ
Sbjct: 9 LYVGNLSRDVTEPLILQVFTQIGPCKSCKMIVDTAGNDP--YCFVEFYDHRHAAASLAAMNGRKIMGKEVKVNWATT--PTSQKKD-------------TSNHFHVFVGDLSPEITTEDVKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQHMGGQWLGGRQIRTNWATRKPPAPKTTYESNSKHLSFEEVMSQSSPSNCTVYCGGVS---SGLTEQLMRQTFSAFG---QIMEVRVFPDKGYSFVSAISNGGVMEPTQGLNGSMLANQ 266
BLAST of Nucleolysin TIA-1 isoform p40 vs. Planmine SMEST
Match: SMESG000073709.1 (SMESG000073709.1) HSP 1 Score: 798.119 bits (2060), Expect = 0.000e+0 Identity = 382/382 (100.00%), Postives = 382/382 (100.00%), Query Frame = 2
Query: 461 MWGDFMLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHPNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNGLINQFSTARGMNS 1606
MWGDFMLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHPNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNGLINQFSTARGMNS
Sbjct: 1 MWGDFMLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHPNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNGLINQFSTARGMNS 382
BLAST of Nucleolysin TIA-1 isoform p40 vs. Planmine SMEST
Match: SMESG000073709.1 (SMESG000073709.1) HSP 1 Score: 786.178 bits (2029), Expect = 0.000e+0 Identity = 377/377 (100.00%), Postives = 377/377 (100.00%), Query Frame = 2
Query: 476 MLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHPNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNGLINQFSTARGMNS 1606
MLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHPNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNGLINQFSTARGMNS
Sbjct: 1 MLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHPNHPLLPALQAMTSGMQLNKYKTVGELNRYQTHTLTIPQLTLAPQNHAPITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNLHNLTSPDFGGYMMSSVPNGLTNSNIGALNGLINQFSTARGMNS 377
BLAST of Nucleolysin TIA-1 isoform p40 vs. Planmine SMEST
Match: SMESG000055085.1 (SMESG000055085.1) HSP 1 Score: 150.984 bits (380), Expect = 1.774e-40 Identity = 80/239 (33.47%), Postives = 133/239 (55.65%), Query Frame = 2
Query: 659 QLNKYKTVGELNRYQTHTLTIP------------QLTLAPQNHAPITNIS-IQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRR-PPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKES 1333
Q+N Y + E N +Q +L + ++ A + P +NI+ ++ D S IFVGDI ++ Q L++ FS FG + + K+++ Q KG+ F+++ +++AE A+ M+ +L R I+ NWA R + K P Y V+ + +N +YV GIT L EEL+R F+EFG I V++F +K YAF+ + +HE A +AI + HG ++ + + KC+WGKE+
Sbjct: 45 QINPYAFI-EFNEHQAASLAVAGMNNISLWGHQLKVNWASGSQNPASNITNVKVDYSKAIQIFVGDIGLDVNEQMLKDAFSQFGSIIDVKVVRYPDGQS-KGFAFLSFTNRQDAENAITSMHKTWLHNRTIKCNWATRNGTDEEQFKQYTPRPYELVYKEAPLTNTNVYVAGITENLTEELVRCHFEEFGRIDSVKVFPDKAYAFINYSTHEAAARAISQRHGYKINNNVVKCNWGKEN 281 HSP 2 Score: 91.6633 bits (226), Expect = 7.223e-20 Identity = 67/242 (27.69%), Postives = 113/242 (46.69%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFK-----EKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNL-HNLT 1489
D +N+ I+VG++ EI Q L F FG+ C I++D Q Y F+ + + A A+ MN L Q++ NWA +DY++ I+VG I + E++L+++F +FG I++V++ + KG+AF+ F + + A AI MH + ++ KC+W + +E F Y PY L+ ++ P TN NV ++ + NLT
Sbjct: 2 DPTNNKCIYVGNLPHEITDQLLLTVFGHFGQCVGCHIMRDFSGQI-NPYAFIEFNEHQAASLAVAGMNNISLWGHQLKVNWASGSQNPASNITNVKVDYSKAI--------QIFVGDIGLDVNEQMLKDAFSQFGSIIDVKVVRYPDGQSKGFAFLSFTNRQDAENAITSMHKTWLHNRTIKCNWATRNGTDEEQ--------FKQY---TPRPYELVYKEAP---LTNTNVYVAGITENLT 220
BLAST of Nucleolysin TIA-1 isoform p40 vs. Planmine SMEST
Match: SMESG000044648.1 (SMESG000044648.1) HSP 1 Score: 145.591 bits (366), Expect = 7.054e-39 Identity = 73/188 (38.83%), Postives = 112/188 (59.57%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQ----KPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKES 1333
D SN IFVGDI +++ L+E FS FG V + K+++ Q +G+ FVAY+ +E+AE+A+ M+ + R I+ NWA R DQ P Y V+ + +N +Y+ GI G+ EEL+R F+EFG I V+I++EK +AF+ F +HE A +AI + HG ++ + KC+WGKE+
Sbjct: 100 DYSNTIQIFVGDIGLDVDESMLKEGFSKFGSVIDAKVVRYQDGQS-RGFAFVAYSRREDAEKAIENMHKTWFHNRTIKCNWATRNGLD---GDQFIKYTPRPYELVYKEAPLTNTNVYIAGIPEGITEELIRVHFEEFGRIDAVKIYQEKAHAFINFVTHEAAARAISQRHGYKINESVIKCNWGKEN 283 HSP 2 Score: 85.5001 bits (210), Expect = 7.091e-18 Identity = 64/239 (26.78%), Postives = 106/239 (44.35%), Query Frame = 2
Query: 782 DTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRP--PQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFK-----EKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNL 1477
D N+ I+VG++ I L F FG+ C II+D Q Y F+ Y A AL M+G ++ QI+ NW+ P +DY+ + I+VG I + E +L+E F +FG +++ ++ + +G+AFV + E A +AI MH ++ KC+W ++N + I P PY L+ ++ P TN NV ++ +
Sbjct: 2 DIRNNRTIYVGNLPDAITDHLLLRIFGNFGQCASCHIIRDFSGQ-TNPYAFIEYTNHSAASLALAAMDGIYMWNNQIKVNWSSGNSLGTAAPAITASKIDYS--------NTIQIFVGDIGLDVDESMLKEGFSKFGSVIDAKVVRYQDGQSRGFAFVAYSRREDAEKAIENMHKTWFHNRTIKCNWA---------TRNGLDGDQFIKYTP--RPYELVYKEAP---LTNTNVYIAGI 217
BLAST of Nucleolysin TIA-1 isoform p40 vs. Planmine SMEST
Match: SMESG000055074.1 (SMESG000055074.1) HSP 1 Score: 136.346 bits (342), Expect = 1.815e-35 Identity = 72/200 (36.00%), Postives = 113/200 (56.50%), Query Frame = 2
Query: 752 APITNISIQEDTSNHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAIRRPPQPPGKDQK------PLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFKEKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKES 1333
P S + D SN IFVGDI +++ L+E FS FG++ + K+++ Q +G+ FV+++ ++EAE A+ M+ + R I+ NWA R G D + P Y V+ + +N +YV G L EELL F+EFG I V+++ EKG+AF+ F +HE A +AI + HG ++ + KC+WGKE+
Sbjct: 90 GPAAVTSAKIDYSNSVQIFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQS-RGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWATRN-----GLDGEQFIKYTPRPYELVYKEAPLTNTNVYVAG--ENLTEELLNCHFQEFGRIDSVKVYPEKGHAFINFVTHEAAARAISQRHGYKINDNVIKCNWGKEN 281 HSP 2 Score: 97.0561 bits (240), Expect = 8.330e-22 Identity = 65/236 (27.54%), Postives = 109/236 (46.19%), Query Frame = 2
Query: 791 NHYHIFVGDIAPEIETQFLRERFSLFGRVTECKIIKDMHTQKPKGYGFVAYATKEEAEEALNKMNGKFLGTRQIRTNWAI--RRPPQPPGKDQKPLDYNEVFAASSESNCTIYVGGITNGLCEELLRESFKEFGDILEVRIFK-----EKGYAFVRFDSHEGATQAIIRMHGKEVGSQLCKCSWGKESNDLKETSQNSILNPFSIYINPVGYPYSLLTQQLPDLSTTNYNVSLSNL 1477
N+ I+VG++ + Q L F FG+ C II+D Q Y F+ Y A AL+ M+G ++ QI+ NW+ P P +DY+ ++ I+VG I + E +L+E F +FG +++ ++ + +G+AFV F + + A +AI MH ++ KC+W + E +I PY L+ ++ P L+ TN V+ NL
Sbjct: 5 NNRTIYVGNLPDAVNDQLLIRIFGNFGQCISCHIIRDFSCQT-NPYAFIEYTDHPSASLALSAMDGIYMWNNQIKVNWSSGPSTIPGPAAVTSAKIDYS--------NSVQIFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQSRGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWATRNGLDGEQ-----------FIKYTPRPYELVYKEAP-LTNTNVYVAGENL 219 The following BLAST results are available for this feature:
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Nucleolysin TIA-1 isoform p40 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30029672 ID=SMED30029672|Name=Nucleolysin TIA-1 isoform p40|organism=Schmidtea mediterranea sexual|type=transcript|length=1748bpback to top protein sequence of SMED30029672-orf-1 >SMED30029672-orf-1 ID=SMED30029672-orf-1|Name=SMED30029672-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=383bp MWGDFMLLPNLYKPVDNSSSAVTATAIGLTTNPLLNPALCPNAANSIFAHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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