tRNA:m(4)X modification enzyme TRM13-like

Overview
NametRNA:m(4)X modification enzyme TRM13-like
Smed IDSMED30029653
Length (bp)1349
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of tRNA:m(4)X modification enzyme TRM13-like (SMED30029653) t-SNE clustered cells

Violin plots show distribution of expression levels for tRNA:m(4)X modification enzyme TRM13-like (SMED30029653) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of tRNA:m(4)X modification enzyme TRM13-like (SMED30029653) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for tRNA:m(4)X modification enzyme TRM13-like (SMED30029653) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029653

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30029653SMESG000038196.1 SMESG000014287.1 Contig5258newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30029653SMESG000038196.1 SMESG000014287.1 Contig5258uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30029653SMESG000029925.1 Contig5258newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30029653SMESG000029925.1 Contig5258uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
X1 cellSMED30029653SMESG000014287.1 SmedASXL_011711SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30029653SMESG000014287.1 dd_Smed_v4_7596_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Human
Match: TRMT13 (tRNA methyltransferase 13 homolog [Source:HGNC Symbol;Acc:HGNC:25502])

HSP 1 Score: 211.46 bits (537), Expect = 1.493e-62
Identity = 148/469 (31.56%), Postives = 236/469 (50.32%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRK--NVLAKD-----DGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH-KKGPKFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCLKNWM-------DKECLSK--ENIKTR---------------------LKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATC-----------------------------GDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGR-KYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C ++V +K R+CR +      FC EH+     E++ +R++CP+D KH+VYE +L +HLK CN+       FY + IN+G     E   +++ ++ ++ ++++++I  + +  +  N   KD       ++D       G++++        KH  Q A+++ N+   K+L         F+EFGAG+G  SH+++ ++  A  V      FIL+++   R + D KH KK   FER+ +DI HL LNK+  ++ +++ VV   KHLCG ATDL LRCL           ++E L+K  +N KT                      + GIVIALCCHH+C+W+ Y+ K + R LGL + +FH    MS WATC                             G +R TD   + L     + EKK+IG LCK ++D GR +Y  +K F   +  ++ Y D  V+LEN  L
Sbjct:   19 CGYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFYIQDINAGLRDETEIPEQLVPISSLSEEQLEKLIKKLRKASEGLNSTLKDHIMSHPALHDALNDPKNGDSAT--------KHLKQQASILGNIENLKLLGPR----RCFVEFGAGKGKLSHWVDIALKDAEKV-----HFILVEKVTTRFKVDGKHRKKNSVFERLQIDIQHLCLNKIPVLREEKLPVVGIGKHLCGMATDLALRCLVETYAASFEERNEEPLAKRIKNDKTEKEIYTLAKEGNEKNVPEKWNPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSLETSNSTTKRQDNQNDDSEEHDDGGYRITDDGADCLPGLLSVEEKKKIGHLCKLLIDQGRIQYLQQKGF---SPALQYYTDPLVSLENVLL 467
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Human
Match: TRMT13 (tRNA methyltransferase 13 homolog [Source:HGNC Symbol;Acc:HGNC:25502])

HSP 1 Score: 72.4034 bits (176), Expect = 5.120e-15
Identity = 33/78 (42.31%), Postives = 50/78 (64.10%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP-FYSEKIN 313
            C ++V +K R+CR +      FC EH+     E++ +R++CP+D KH+VYE +L +HLK CN+   K KP FY + IN
Sbjct:   19 CGYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSRE-KPKPDFYIQDIN 95
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Human
Match: TRMT13 (tRNA methyltransferase 13 homolog [Source:HGNC Symbol;Acc:HGNC:25502])

HSP 1 Score: 72.4034 bits (176), Expect = 2.141e-14
Identity = 30/77 (38.96%), Postives = 47/77 (61.04%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKIN 313
            C ++V +K R+CR +      FC EH+     E++ +R++CP+D KH+VYE +L +HLK CN+       FY + IN
Sbjct:   19 CGYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFYIQDIN 95
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Human
Match: TRMT13 (tRNA methyltransferase 13 homolog [Source:HGNC Symbol;Acc:HGNC:25502])

HSP 1 Score: 56.9954 bits (136), Expect = 2.341e-9
Identity = 27/57 (47.37%), Postives = 39/57 (68.42%), Query Frame = 2 
Query:  146 FCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP-FYSEKIN 313
            FC EH+     E++ +R++CP+D KH+VYE +L +HLK CN+   K KP FY + IN
Sbjct:    9 FCGEHAGAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSR-EKPKPDFYIQDIN 64
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Celegans
Match: Y49A3A.3 (pep chromosome:WBcel235:V:14354410:14355754:1 gene:WBGene00013026.1 transcript:Y49A3A.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y49A3A.3)

HSP 1 Score: 112.464 bits (280), Expect = 3.316e-27
Identity = 98/406 (24.14%), Postives = 182/406 (44.83%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYD-AKHKKGP--KFERILMDISHLNLNKVETVKN-KRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSK-QFHLMTMMSGWATCGDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFV 1285
            C++ +  K R C+ + K  N FC EHSI  H +N+  R++CP D KH++ +  L  HL  CN+ I   +     KI++ S  GE   ++ +       +    +  +      +V+ +       N       A +        K  +Q ++++ ++    +L     +     E GAG+G  ++++ ++          N  +IL+DR G RN++D A  ++ P    +R    I H++L+K++ +KN ++I  + KH CG+ATD  +R L            N   +    ++  CCHHK  +  Y    ++ +  +N +  F  +  ++ +AT G     DT   E      I    E+G   K I+++GR  ++E   G    ++  Y+   V+ EN  +  
Sbjct:   16 CEYILPIKKRRCKMLVKKGNRFCGEHSI--HDQNNTDRMVCPNDGKHTILKADLEIHLTRCNSRIRDAEYI---KIDANSIRGETKRTDKIDRRATEDEICTTVHKIWKCYETDVMDRLIVEQQRNELVEQNIAQNSDLNNTKKKQLYQISSILGHIESTGLLPTC--SKSCMFELGAGKGQLAYWISKAAP--------NGNYILMDRSGSRNKFDTAAFRENPNLSMKRFRCSIEHMDLSKIDELKNSEKILAICKHFCGSATDAGIRSLM-----------NSGLQFNAALLIPCCHHKSRFAEYGGHDFLEKWEMNDEASFAALRYIASFATNG---AVDTEATE--GWKSIHPPLELGRRAKAILEIGRAIWLES-VGF-KTRVVEYVPPEVSPENLLILA 388
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Fly
Match: CG18048 (gene:FBgn0037435 transcript:FBtr0081712)

HSP 1 Score: 171.785 bits (434), Expect = 3.182e-48
Identity = 127/437 (29.06%), Postives = 216/437 (49.43%), Query Frame = 2 
Query:   74 ANVCKFFVARKNRYCRGMTKNSNEFCPEHSI---------DNHSENSMR-RVICPVDNKHSVYEHKLIQHLKVCNANIPKTK-PFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD--KHTFQYANLIENMNKRKMLNV-----SPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKGPKFERILMDISHLNLNKV-ETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCG--------------DFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFV 1285
               C ++V RK R C+      +EFC  H+          +   E+S + R+ CP+D+KH+V++ KL +HL +CNA   ++  P+  + +NSG +  E D        D+N     ++  L  E   +++ K   +YD ++ ++  E       +K +  +  +    L +      +L +       ++   ++EFGAG+G  ++FL    +      L +   +LIDR  +R++ D K       +RI  DI+ L L+ + E  K +R    SKHLCG ATDLTLRC+        L   N  +    ++IALCCHH+C+W+SY+ + +++E G+  ++F ++T M  WA CG              DF+ T+T  + L       E+++IG  CKR++D GR   + +  G    ++K Y+ + VTLEN  L  
Sbjct:   18 TTTCSYWVLRKKRRCKMTANKGSEFCGAHASSAATTATCDEKAREDSFQERIPCPLDHKHTVFKRKLAKHLTICNARDQESSLPYIVKGVNSGDNLKETD-------EDLNKFNQIKLHELADEEFYSLIDKVKNLYDKHINSSIQELQLEHESLKEELSRKDYGQETLRQLTQTTSLLGILEHDHQLMDHTSYIEFGAGKGQLAYFL---ATVLQEQKLSHSQVVLIDRMSLRHKKDNKLANREVVQRIRADIADLKLSALPELKKTQRTVAFSKHLCGAATDLTLRCI--------LGDGNASSDY--VLIALCCHHRCSWRSYVGRKFLQEAGIGPREFVILTKMVSWAVCGTGLSRERRKAMESADFQLTETNTQRLTRQ----EREQIGQQCKRVLDYGRLEHL-RSHGY-QAELKFYVPRDVTLENVVLLA 428
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Zebrafish
Match: trmt13 (tRNA methyltransferase 13 homolog [Source:ZFIN;Acc:ZDB-GENE-050327-19])

HSP 1 Score: 204.912 bits (520), Expect = 2.141e-60
Identity = 155/456 (33.99%), Postives = 235/456 (51.54%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP-FYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD---KHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKG-PKFERILMDISHLNLNKVETVKNKRIFV--VSKHLCGTATDLTLRCLKNWMDKECLSKENIKT--RLK------------------------------GIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDT-----RFEE----------LLNANG---ITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C F+V +K RYC+ +  +   FC EH+ +   E   +R+ CP+DNKH+V+E  L +HLK CN+   K KP +Y + IN+G  S +E   EI       AD  KE ++ +I   KN L   +     N  +++    S       D   KH  Q A+++ NM   ++L  SP     ++EFGAG+G  SH++  ++  A     +N+ F+L++R   R + D KHK     F+R+ +DI HL+L KV  ++ K + V  V KHLCG ATDL LRCL    +  C SK++     R+K                              G+ IALCCHH+C+W+ Y+ K + RE GL  ++F     MS WATCG  +  +T     R EE          L   NG   + ++++IG LCKR++D GR ++++K+   T+  +K Y  + V+LEN  L
Sbjct:   16 CAFYVVKKKRYCKMIVGSGKTFCGEHA-NAGEEGERKRIPCPLDNKHTVFEDNLTKHLKKCNSK-EKPKPIYYVKDINAGCASEDETVKEI-----SIADRTKEELDDLIVKLKNALQGLNTKLIENTLSHSALHESLNDPKNGDSAFKHLKQQASILGNMEALELL--SP--NRCYIEFGAGKGKLSHWIHIALKSA-----ENVHFLLVERSSTRFKVDGKHKNADSTFDRLQVDIQHLDLRKVPLLREKGLPVIGVGKHLCGAATDLALRCL---FEHNCTSKDDEPPFKRVKLNQAEGAGGKDMKPVPSTEGRETGKEIVVSGLAIALCCHHRCDWRHYVGKEFFRERGLGPEEFAAFQRMSSWATCGMRKAAETTSEHKRDEEKEHEMSDEAVLDTLNGFMSVEDREQIGRLCKRLIDHGRVHYLQKKGFKTS--MKYYTSRDVSLENVLL 450
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Zebrafish
Match: trmt13 (tRNA methyltransferase 13 homolog [Source:ZFIN;Acc:ZDB-GENE-050327-19])

HSP 1 Score: 204.527 bits (519), Expect = 2.644e-60
Identity = 155/456 (33.99%), Postives = 235/456 (51.54%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP-FYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD---KHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKG-PKFERILMDISHLNLNKVETVKNKRIFV--VSKHLCGTATDLTLRCLKNWMDKECLSKENIKT--RLK------------------------------GIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDT-----RFEE----------LLNANG---ITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C F+V +K RYC+ +  +   FC EH+ +   E   +R+ CP+DNKH+V+E  L +HLK CN+   K KP +Y + IN+G  S +E   EI       AD  KE ++ +I   KN L   +     N  +++    S       D   KH  Q A+++ NM   ++L  SP     ++EFGAG+G  SH++  ++  A     +N+ F+L++R   R + D KHK     F+R+ +DI HL+L KV  ++ K + V  V KHLCG ATDL LRCL    +  C SK++     R+K                              G+ IALCCHH+C+W+ Y+ K + RE GL  ++F     MS WATCG  +  +T     R EE          L   NG   + ++++IG LCKR++D GR ++++K+   T+  +K Y  + V+LEN  L
Sbjct:   21 CAFYVVKKKRYCKMIVGSGKTFCGEHA-NAGEEGERKRIPCPLDNKHTVFEDNLTKHLKKCNSK-EKPKPIYYVKDINAGCASEDETVKEI-----SIADRTKEELDDLIVKLKNALQGLNTKLIENTLSHSALHESLNDPKNGDSAFKHLKQQASILGNMEALELL--SP--NRCYIEFGAGKGKLSHWIHIALKSA-----ENVHFLLVERSSTRFKVDGKHKNADSTFDRLQVDIQHLDLRKVPLLREKGLPVIGVGKHLCGAATDLALRCL---FEHNCTSKDDEPPFKRVKLNQAEGAGGKDMKPVPSTEGRETGKEIVVSGLAIALCCHHRCDWRHYVGKEFFRERGLGPEEFAAFQRMSSWATCGMRKAAETTSEHKRDEEKEHEMSDEAVLDTLNGFMSVEDREQIGRLCKRLIDHGRVHYLQKKGFKTS--MKYYTSRDVSLENVLL 455
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Xenopus
Match: trmt13 (tRNA methyltransferase 13 homolog (S. cerevisiae) [Source:NCBI gene;Acc:100379916])

HSP 1 Score: 197.208 bits (500), Expect = 2.581e-57
Identity = 138/454 (30.40%), Postives = 218/454 (48.02%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP-FYSEKINXXXXXXXXXXXXIL-------KLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKGPKFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCL--------------------------KNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCG-------------------DFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C  FV RK R+C+ +     +FC EH+      +S RR+ CP+D KH+VYE +L +HLK CN+   K KP FY + +N+G    E  D++I        +L ++     +    L        L     +  +N  AN   AS         KH  Q A+++ +++   +L+     +  F+EFGAGRG  SH+++ +   +     +N+ F+L++R   R + D K +    FER+ +DI HL L +V ++  K++ V+   KHLCG  TDL LRCL                          KN  DK   +     T + GI IALCCHH+C+W  Y+ + + + LGL+ ++F L   MS WATCG                   D  + +   E +     + E++ +G LCK ++D GR  F+++   +  +Q   Y +  V+LEN  L
Sbjct:   31 CSHFVQRKKRFCKMIVSEGKKFCGEHAQSGEEHDSRRRIPCPLDPKHTVYEDQLPKHLKKCNSR-EKPKPVFYVQDVNAGCLITETPDNQISLSSLSKDELQELTEKLKQVTSGLDPPAADKKLCHWSLLEALNDPANGDTAS---------KHLKQQASILGHLDNLGLLS----GSCCFVEFGAGRGKLSHWVDIATQGS-----ENINFLLVERATTRFKVDGKQRSS-VFERLQIDIQHLCLGRVPSLNEKQLPVIGIGKHLCGAGTDLALRCLMQSNSLANGEPFPKKPRTDTFEQGTVKNECDK---ANPAYSTCVGGIAIALCCHHRCDWHHYVGREFFQSLGLDQREFSLFQRMSSWATCGMRLPAKAIQSDEQMESEEHDAEQQNCHSETVERFLTVKERESLGRLCKLLIDYGRVDFLQRMGYIAALQY--YTEPEVSLENVLL 459
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Mouse
Match: Trmt13 (tRNA methyltransferase 13 [Source:MGI Symbol;Acc:MGI:1925219])

HSP 1 Score: 213.386 bits (542), Expect = 1.805e-63
Identity = 144/464 (31.03%), Postives = 232/464 (50.00%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD---KHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH-KKGPKFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCL-----------------------KNWMDKECLSKENIK-------TRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATC----------------------------GDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGR-KYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C +FV +K R+CR +      FC EH+     EN+ +R++CP+D KH+VYE +L +HLK CN+       F+ + IN+G     E   +++  + ++ ++++ +I  + +  + +    +  ++ ++ ++     +       D   KH  Q A+++ N+ K K+L         F+EFGAG+G  SH+++ ++  A     +N+ FIL++R   R + D KH KK   FER+ +DI HL LN+V  ++  R+ VV   KHLCG ATD+ LRCL                       K   +   L+KE  +       T + GIVIALCCHH+C+W+ Y+ K + + LGL + +F+    MS WATC                            G  R TD   + L     + EKK+IG LCK ++D GR +Y  +K F   +  ++ Y D  V+LEN  L
Sbjct:   19 CNYFVEKKKRFCRMVAAAGKRFCGEHAGSAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFFIQDINAGLKDETEIPEQLVPFSSLSEEQLENLIKKLRKASEGL----NSTHEDHIMSHPALHDALNDPRNGDCAVKHLKQQASILGNIEKLKLLGPR----RCFVEFGAGKGKLSHWVDIALKDA-----ENVHFILVERVTTRFKVDGKHRKKDSVFERLQIDIQHLCLNRVPVLREGRLPVVGIGKHLCGVATDVALRCLVETYAASFEEKDEEPLAKRIKNDKTEKESNTLAKEGSEKDVPETWTPVAGIVIALCCHHRCDWRHYVGKEYFKALGLGAVEFYYFQRMSSWATCGMRTSLEGSDVTPERKDAQRDENEEHDDGGDRLTDGNTDSLPGILTVEEKKKIGHLCKLLIDQGRLQYLQQKGF---SPALQYYTDPLVSLENVLL 466
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Mouse
Match: Trmt13 (tRNA methyltransferase 13 [Source:MGI Symbol;Acc:MGI:1925219])

HSP 1 Score: 135.576 bits (340), Expect = 5.538e-36
Identity = 85/270 (31.48%), Postives = 149/270 (55.19%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD---KHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH-KKGPKFERILMDISHLNLNKVETVKNKRIFVV--SKHLCGTATDLT 874
            C +FV +K R+CR +      FC EH+     EN+ +R++CP+D KH+VYE +L +HLK CN+       F+ + IN+G     E   +++  + ++ ++++ +I  + +  + +    +  ++ ++ ++     +       D   KH  Q A+++ N+ K K+L         F+EFGAG+G  SH+++ ++  A     +N+ FIL++R   R + D KH KK   FER+ +DI HL LN+V  ++  R+ VV   KHLCG AT +T
Sbjct:   19 CNYFVEKKKRFCRMVAAAGKRFCGEHAGSAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFFIQDINAGLKDETEIPEQLVPFSSLSEEQLENLIKKLRKASEGL----NSTHEDHIMSHPALHDALNDPRNGDCAVKHLKQQASILGNIEKLKLLG----PRRCFVEFGAGKGKLSHWVDIALKDA-----ENVHFILVERVTTRFKVDGKHRKKDSVFERLQIDIQHLCLNRVPVLREGRLPVVGIGKHLCGVATGVT 275
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Mouse
Match: Trmt13 (tRNA methyltransferase 13 [Source:MGI Symbol;Acc:MGI:1925219])

HSP 1 Score: 73.9442 bits (180), Expect = 4.949e-15
Identity = 31/77 (40.26%), Postives = 47/77 (61.04%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKIN 313
            C +FV +K R+CR +      FC EH+     EN+ +R++CP+D KH+VYE +L +HLK CN+       F+ + IN
Sbjct:   19 CNYFVEKKKRFCRMVAAAGKRFCGEHAGSAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFFIQDIN 95
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Mouse
Match: Trmt13 (tRNA methyltransferase 13 [Source:MGI Symbol;Acc:MGI:1925219])

HSP 1 Score: 54.299 bits (129), Expect = 2.682e-9
Identity = 24/49 (48.98%), Postives = 34/49 (69.39%), Query Frame = 2 
Query:  146 FCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP 292
            FC EH+     EN+ +R++CP+D KH+VYE +L +HLK CN+   K KP
Sbjct:    1 FCGEHAGSAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNSR-EKPKP 48
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Mouse
Match: Trmt13 (tRNA methyltransferase 13 [Source:MGI Symbol;Acc:MGI:1925219])

HSP 1 Score: 51.9878 bits (123), Expect = 2.113e-7
Identity = 43/176 (24.43%), Postives = 90/176 (51.14%), Query Frame = 2 
Query:  224 SVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD---KHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH 742
            +VYE +L +HLK CN+       F+ + IN+G     E   +++  + ++ ++++ +I  + +  + +    +  ++ ++ ++     +       D   KH  Q A+++ N+ K K+L         F+EFGAG+G  SH+++ ++  A     +N+ FIL++R   R + D KH
Sbjct:   17 TVYEDQLAKHLKKCNSREKPKPDFFIQDINAGLKDETEIPEQLVPFSSLSEEQLENLIKKLRKASEGL----NSTHEDHIMSHPALHDALNDPRNGDCAVKHLKQQASILGNIEKLKLLGPR----RCFVEFGAGKGKLSHWVDIALKDA-----ENVHFILVERVTTRFKVDGKH 179
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. UniProt/SwissProt
Match: sp|Q8BYH3|TRM13_MOUSE (tRNA:m(4)X modification enzyme TRM13 homolog OS=Mus musculus OX=10090 GN=Trmt13 PE=2 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 1.262e-62
Identity = 144/464 (31.03%), Postives = 232/464 (50.00%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD---KHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH-KKGPKFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCL-----------------------KNWMDKECLSKENIK-------TRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATC----------------------------GDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGR-KYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C +FV +K R+CR +      FC EH+     EN+ +R++CP+D KH+VYE +L +HLK CN+       F+ + IN+G     E   +++  + ++ ++++ +I  + +  + +    +  ++ ++ ++     +       D   KH  Q A+++ N+ K K+L         F+EFGAG+G  SH+++ ++  A     +N+ FIL++R   R + D KH KK   FER+ +DI HL LN+V  ++  R+ VV   KHLCG ATD+ LRCL                       K   +   L+KE  +       T + GIVIALCCHH+C+W+ Y+ K + + LGL + +F+    MS WATC                            G  R TD   + L     + EKK+IG LCK ++D GR +Y  +K F   +  ++ Y D  V+LEN  L
Sbjct:   19 CNYFVEKKKRFCRMVAAAGKRFCGEHAGSAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFFIQDINAGLKDETEIPEQLVPFSSLSEEQLENLIKKLRKASEGL----NSTHEDHIMSHPALHDALNDPRNGDCAVKHLKQQASILGNIEKLKLLGPR----RCFVEFGAGKGKLSHWVDIALKDA-----ENVHFILVERVTTRFKVDGKHRKKDSVFERLQIDIQHLCLNRVPVLREGRLPVVGIGKHLCGVATDVALRCLVETYAASFEEKDEEPLAKRIKNDKTEKESNTLAKEGSEKDVPETWTPVAGIVIALCCHHRCDWRHYVGKEYFKALGLGAVEFYYFQRMSSWATCGMRTSLEGSDVTPERKDAQRDENEEHDDGGDRLTDGNTDSLPGILTVEEKKKIGHLCKLLIDQGRLQYLQQKGF---SPALQYYTDPLVSLENVLL 466
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. UniProt/SwissProt
Match: sp|Q9NUP7|TRM13_HUMAN (tRNA:m(4)X modification enzyme TRM13 homolog OS=Homo sapiens OX=9606 GN=TRMT13 PE=1 SV=2)

HSP 1 Score: 211.46 bits (537), Expect = 7.169e-62
Identity = 148/469 (31.56%), Postives = 236/469 (50.32%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRK--NVLAKD-----DGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH-KKGPKFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCLKNWM-------DKECLSK--ENIKTR---------------------LKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATC-----------------------------GDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGR-KYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C ++V +K R+CR +      FC EH+     E++ +R++CP+D KH+VYE +L +HLK CN+       FY + IN+G     E   +++ ++ ++ ++++++I  + +  +  N   KD       ++D       G++++        KH  Q A+++ N+   K+L         F+EFGAG+G  SH+++ ++  A  V      FIL+++   R + D KH KK   FER+ +DI HL LNK+  ++ +++ VV   KHLCG ATDL LRCL           ++E L+K  +N KT                      + GIVIALCCHH+C+W+ Y+ K + R LGL + +FH    MS WATC                             G +R TD   + L     + EKK+IG LCK ++D GR +Y  +K F   +  ++ Y D  V+LEN  L
Sbjct:   19 CGYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFYIQDINAGLRDETEIPEQLVPISSLSEEQLEKLIKKLRKASEGLNSTLKDHIMSHPALHDALNDPKNGDSAT--------KHLKQQASILGNIENLKLLGPR----RCFVEFGAGKGKLSHWVDIALKDAEKV-----HFILVEKVTTRFKVDGKHRKKNSVFERLQIDIQHLCLNKIPVLREEKLPVVGIGKHLCGMATDLALRCLVETYAASFEERNEEPLAKRIKNDKTEKEIYTLAKEGNEKNVPEKWNPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSLETSNSTTKRQDNQNDDSEEHDDGGYRITDDGADCLPGLLSVEEKKKIGHLCKLLIDQGRIQYLQQKGF---SPALQYYTDPLVSLENVLL 467
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. UniProt/SwissProt
Match: sp|A7TSF4|TRM13_VANPO (tRNA:m(4)X modification enzyme TRM13 OS=Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) OX=436907 GN=TRM13 PE=3 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 8.848e-50
Identity = 140/444 (31.53%), Postives = 224/444 (50.45%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKN-SNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNA----NIPKTKPFY--------SEKINXXXXXXXXXXXXILKL-----NDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKG----------PKFERILMDISHLNLNKVETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQ---------FHLMTMMSGWATCGDFRKT-----DTRFEELLNANGITEKKEIGLLCKRIMDLGRKYFIEKEFGLT-NVQIKPYIDQSVTLENCALFV 1285
            C+F++ +K R C GM++N S+++C EH I N  EN+ +R+ CP+D  H+V+E  L  HLK CN     +    KP++        +E  N+   + +   + I+K      N    DE   + N+ ++IRKN   +D     +N   N G+            H  Q ++LI+NM  R +L     +   F+EFG GR   S ++ + +   S   + N  FILIDR   R ++D K KK           P   RI +DI  L ++ +   K+ +   +SKHLCG ATDLTLR L    D            L+G+ IA+CC H CN  +Y+N  +++ +  N+           FH +T ++ WAT GD R T     +T F  L      TE++E+GL+ +R++D GR  +++++ G +  V++  Y++ S++LEN AL  
Sbjct:   12 CEFYMEKKKRRC-GMSRNLSSKYCSEHQILN--ENT-KRIPCPLDPNHTVWESDLDSHLKKCNKLKLIHQHDNKPYFLKDCNAITTEDSNTTVITKDSLQNWIMKTIPVLKNFFKDDEKNYLSNVPLDIRKNHTMEDKRFPQLNENDNIGKKY----------HAIQQSSLIQNMIDRNILQFKENSLANFIEFGCGRAELSRYVNQVVIKNSEEKIYNPHFILIDRSTNRMKFDTKMKKDALEFNQNLNPPTITRIRIDIKDLKIDPL-LQKDSKYIAISKHLCGVATDLTLRSLTYNPDDNDF--------LQGVCIAMCCRHVCNSNNYVNPDFVKSIIGNTNTEEQLPYDQFFHALTKIAAWATSGD-RPTSSDENNTHFTNL----PYTERQELGLMARRVIDQGRCDWLQQKLGESFKVELIRYVEPSISLENVALLA 427
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. UniProt/SwissProt
Match: sp|Q12383|TRM13_YEAST (tRNA:m(4)X modification enzyme TRM13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TRM13 PE=1 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 4.074e-41
Identity = 132/472 (27.97%), Postives = 223/472 (47.25%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNS-NEFCPEH----------SIDN----HSENSMRRVICPVDNKHSVYEHKLIQHLKVCN----ANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD-KHTFQYANLIENM------NKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSM-SCASSVPLDNL-----TFILIDRQGVRNRYDAKHKKG---------------PKFERILMDISHLNLNKV--ETVKNKRIFV-VSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQ----------FHLMTMMSGWATCGDFRKTDTRFEELLNAN-----------GITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFV 1285
            C++F+ +K R C GMT++S N +C EH           + N     +E    RV CP+D  H+V+  +L +HLK CN    +++   KP+Y    N  +              D+ A+ + + I L+ ++ +     +  +  +N   N   +     Q+ S+ KH  Q ++LIEN+       + + LN        F+EFG GR  FS ++   + +  +S+P ++       F+LIDR   R ++D K K                 P  +RI +DI  L ++ +   T  +   +V +SKHLCG ATDLTLRC+ N              +LK I IA+CC H C++  Y+N+S++  L    +           F ++T +  W TCG  RK  T   +++N              I E++ IGL+ +R++D GR  +++++F   N ++  Y++  V+LEN A+ V
Sbjct:   21 CEYFMEKKKRRC-GMTRSSQNLYCSEHLNLMKKAANSQVHNKNGSEAEKERERVPCPLDPNHTVWADQLKKHLKKCNKTKLSHLNDDKPYYEPGYNGENGLLSSSVKI-----DITAEHLVQSIELLYKVFEGESMDELPLRQLN---NKLMSLKRFPQLPSNTKHAVQQSSLIENLVDAGAFERPESLN--------FIEFGCGRAEFSRYVSLYLLTQLTSLPAEHSGSNSNEFVLIDRATNRMKFDKKIKDDFSEIKSNSPSKPISCPSIKRIKIDIRDLKMDPILKSTPGDDIQYVCISKHLCGVATDLTLRCIGNSSILHGDDNNGCNPKLKAICIAMCCRHVCDYGDYVNRSYVTSLVEKYRAHGSILTYETFFRVLTKLCSWGTCG--RKPGTAITDIVNVVESFEGAEPYTITIKERENIGLMARRVIDEGRLVYVKEKFTEFNAELIRYVESDVSLENVAMLV 473
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. UniProt/SwissProt
Match: sp|A3LXS6|TRM13_PICST (tRNA:m(4)X modification enzyme TRM13 OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) OX=322104 GN=TRM13 PE=3 SV=2)

HSP 1 Score: 144.05 bits (362), Expect = 3.397e-37
Identity = 124/436 (28.44%), Postives = 206/436 (47.25%), Query Frame = 2 
Query:  101 RKNRYCRGMTKNSNEFCPEHSIDNHSENSM---------RRVICPVDNKHSVYEHKLIQHLKVCNAN-IPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAK----DDGIYDINVTANTGEASSFVYQMKS---DKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFL------ERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKG---------PKFERILMDISHLNLNK-VETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKS--WIRELGLNSK-QFHLMTMMSGWATCGDFRKTDTRFEELLNANGITE-----KKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFV 1285
            +KNR C    K S ++C EH I N S + +          RV CP+D KH+V++  L  HLK CNA  + +T+ ++S+ IN    +   +  +I +  D   D             K++ +K     +GI    +     E S    ++      KH  Q ++LI N+   K+L  SP NT  F+EFG G+   S F+      +      + V L+N  +  IDR   R + D K  K          P+ +R  +DI  L+L+K +  ++  +I  +SKHLCG ATDLTL+              + + +  G++IA+CC H C++   + KS  ++ E G  +   F ++  M  WA C   +K   +  E L A  I++     ++ +G + +R++D  R Y ++       V++  Y+++ VTLEN  L+V
Sbjct:    3 KKNRRCAMRRKGSQKYCSEHIIYNESSSIVNTDTKLSEDERVPCPLDGKHTVWKKNLAVHLKKCNAKPVERTEEWFSKDINVKLKNSLGETEDITRSEDKTLD------------EKDLYSKYIPIIEGINFEPLQYRISEHSGLQQRLNEVLIQKHALQQSSLIGNIKDAKLL--SPNNT--FVEFGCGKAELSRFVNLCLLDDLKQKVNNEVTLENYGYGFIDRGVNRMKMDKKILKDCLDSPIEITPRIQRTRIDIKDLDLDKFINKLQPSKIVAISKHLCGAATDLTLK-----SLLNSSLLSDNRDKFGGLLIAMCCRHVCSYDQLLPKSREYLAEKGFKTPDSFRILKKMVSWAVCS--KKEHAKNVERLEAEHISQLDYSSRERLGFVARRLIDESRVYALKSMLSGFEVKMFWYVEKDVTLENVCLYV 415
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. TrEMBL
Match: A0A2B4S021 (tRNA:m(4)X modification enzyme TRM13-like OS=Stylophora pistillata OX=50429 GN=TRMT13 PE=4 SV=1)

HSP 1 Score: 233.417 bits (594), Expect = 1.203e-67
Identity = 167/482 (34.65%), Postives = 248/482 (51.45%), Query Frame = 2 
Query:   80 VCKFFVARKNRYCRGMTKNSNEFCPEHSI-DNHSENSMR-RVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRK-NVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHK---KGPKFERILMDISHLNLNKVETVK--NKRIFVVSKHLCGTATDLTLRCL--------KNWMDKECLSKENIKTR---------------LKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCG----DFR-----KTDTRFE--------------------ELLNANG-------------------ITEKKEIGLLCKRIMDLGRKYFIE-KEFGLTNVQIKPYIDQSVTLENCALFV 1285
             C FF+ RKNR+CR      +++C EH I D  S+   R R+ CP+D KH+V+E +L  HLK CN        +YS  INSG    E   +E + L+ V  +++  +I+ + E  K +V    + +   NV     E +  V      KH  Q A+LI +M+K  +L    I    FLEFGAGRG  SH+L+ ++  A+     ++ ++LIDR   R +YD  H+   +GP F+R+ +DI HL+L+KV  ++   +R+  VSKHLCG ATDLT+RCL        K  +D  CL     KTR               +KG+++ALCCHH C+W  Y+ + +++ LG  ++ FHL+  +S WATCG    + R     +TD R E                    E L+ N                    I E++EIGL CKR++D GR +++E +EF   N ++  Y+D SV+LEN  L  
Sbjct:   11 TCAFFLKRKNRFCRMTVSGGSKYCGEHRIFDEESKGVGRKRITCPLDGKHTVFEDQLKNHLKKCNQTKKTQVVYYSSNINSGIPDYEFSAAEKVSLSSVCQEKVSRLISKVKECYKAHVPQIPEEVLFHNVFQE--EVTEMVDNPAVLKHLKQQASLIGHMDKLHLLEPRTI----FLEFGAGRGKLSHWLQLAVGSAAK----DVDYLLIDRASNRYKYDRYHRGEDQGPSFQRLNLDIRHLDLSKVPCIQYSKRRVVAVSKHLCGAATDLTIRCLVETLDNTQKQSVDDICLENGADKTRSREDKRIKLDPNERPVKGVILALCCHHCCSWPQYVGRPFLQNLGFTAEDFHLLCCLSSWATCGMRLRERRRGIAGRTDERTENDDRGGDDCHEISTENIASQEFLSKNDEDSKEIKEACEEDRWSNYTIPEREEIGLQCKRLLDTGRLWYLESREF---NARLAFYVDSSVSLENAVLVA 479
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. TrEMBL
Match: A0A1Y1XRP4 (DUF715-domain-containing protein OS=Basidiobolus meristosporus CBS 931.73 OX=1314790 GN=K493DRAFT_331448 PE=4 SV=1)

HSP 1 Score: 228.409 bits (581), Expect = 2.254e-66
Identity = 151/430 (35.12%), Postives = 230/430 (53.49%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSEN-SMRRVICPVDNKHSVYEHKLIQHLKV-CNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAK-------DDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDI-FLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKG---PKFERILMDISHLNLNKVETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDTRFEELLNANGITEKKE----------------IGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFV 1285
            C F+V RK RYC    K +N++C EH +  H +N + +RV CP D  HSVYE +L +H++  CN+  P    ++SE IN    + EE+  +   L+ ++ D ++ +I  I +I    L +        + + D      TG            KH  Q A+L+ +M +R +L      TD  F+EFGAGRG  S +L++++   S       T+IL+DR+  R ++D   + G      ERI MDI  LNL++V  +K K +  +SKHLCG ATDLTL+CL N+++ +   KEN    + GIVIALCCH  C +  Y N+ ++ E+GL+ + F  +TMMS WA CG   K     +E    +  TE+ +                IG  CKRI+D+GR  ++E+  G  + Q+  Y+D+ ++LEN AL  
Sbjct:   23 CHFWVKRKRRYCHLRAKETNQYCGEHLV--HQDNLAQKRVPCPYDPSHSVYESELEKHMQSRCNSRPPPPPVYFSENINVVLPASEEEKPKTT-LSSLDKDRLQSLIEKIRKIHAEQLPELPKEVLHHEALEDRLEVVTTGR-----------KHAIQQASLLGHMKRRDLLT-----TDACFIEFGAGRGELSSYLQKAIDGGSQG-----TYILVDRKKSRGKFDGSIRGGETKATVERIWMDIKDLNLSRVAAIKGKPVVALSKHLCGAATDLTLKCLSNYVEGQ---KEN---GILGIVIALCCHQVCRYNMYPNQEYLTEIGLDDEDFRFLTMMSSWAICGQRPKQGEEPDEHSTKSLDTEETQNDQTHYSGLPHEEREIIGRQCKRILDMGRVKYLER-LGF-DAQLVYYVDREISLENLALIA 420
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. TrEMBL
Match: A7RR85 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g90494 PE=4 SV=1)

HSP 1 Score: 228.794 bits (582), Expect = 2.461e-66
Identity = 156/465 (33.55%), Postives = 240/465 (51.61%), Query Frame = 2 
Query:   50 TDMNESNDANV-CKFFVARKNRYCRGMTKNSNEFCPEH-SIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGI----YDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKG---PKFERILMDISHLNLNKVETV--KNKRIFVVSKHLCGTATD--LTLRCLKNWM--------DKECLSKENIKTRLK---------GIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDTRFEELLNAN----------------------GITEKKEIGLLCKRIMDLGRKYFI-EKEFGLTNVQIKPYIDQSVTLENCALFV 1285
             D  ES    + C F+V RKNRYC+ +     ++C EH  +   + ++ +R++CP+D KHSVYE +L  HLK CN        +Y++ INSG    +    E + L+    D I ++I+ + +       KD+ +    + ++  A   E S   Y     KH  Q A+L+ NM +  +L        ++LEFGAG+G  SH+++++          N+ ++LIDR   R ++D+ HK+G   P F+R+L+DI HLNL ++  +  K +RI  VSKHLCGTAT   LTLRCL + +        D    S++    R K         GIV+ALCCHH+C W  Y+ + ++  LG+  ++FHL+  MS WATCG  R      +E  + N                       I +++EIG  CKR++D GR +++ EK F   N  +  Y+D SV+LEN  L  
Sbjct:    2 ADEQESQPTRITCGFYVKRKNRYCKMIVGKGKKYCGEHMHLSGENGDNRKRILCPLDPKHSVYEDQLKNHLKRCNVKKKTDVVYYAKNINSGIVDYKPSSEEKIPLSSFPQDCISKVIHKLKK-----FFKDNNLEVMPHIMSHDAFKAEMSQENYGPSVHKHLKQQASLVGNMERLGLLQPD----TVYLEFGAGKGKLSHWVQQAHPEGG-----NVEYVLIDRASNRYKFDSCHKRGDNGPDFKRVLLDIEHLNLGELPHLGDKTRRIVAVSKHLCGTATGRYLTLRCLLDTLHGSSATEPDSTLKSEQKDAKRRKLDAAGPSVIGIVVALCCHHQCYWPHYVGRPFLESLGITPQEFHLLCCMSSWATCG-MRPPQGSSKEAEHCNTDESGETDDDNGVDGSDKGLGLSIADREEIGRQCKRLLDAGRVWYLREKGF---NTSLAYYVDSSVSLENVVLLA 448
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. TrEMBL
Match: I3ML36 (tRNA methyltransferase 13 homolog OS=Ictidomys tridecemlineatus OX=43179 GN=TRMT13 PE=4 SV=2)

HSP 1 Score: 223.402 bits (568), Expect = 5.868e-64
Identity = 152/478 (31.80%), Postives = 234/478 (48.95%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXX-------XXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH-KKGPKFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCL-----------------------KNWMDKECLSKE----NIK---TRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATC-----------------------------GDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGR-KYFIEKEFGLTNVQIKPYIDQSVTLENCALFVD*IYSTS 1306
            C ++V +K R+CR +      FC EH+     EN+ +R++CP+D KH+VYE +L +HLK CN+       F+ + IN+G     E   +++ ++ +  D+++       +    +    K+ +     +YD       G++++        KH  Q A+++ N+ K K+L         F+EFGAG+G  SH+++ ++  A  V      FIL+++   R + D KH KK   FER+ +DI HL LNK+  ++  ++ VV   KHLCG ATDL LRCL                       K   +   L+KE    N+    T + GIVIALCCHH+C+W+ Y+ K + R LGL + +FH    MS WATC                             G +R TD   E L     + EKK+IG LCK ++D GR +Y  +K F   N  ++ Y D  V+LEN  L    I+S+ 
Sbjct:   19 CSYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEENARKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFFIQDINAGLKDETEIPEQLVPISSLPEDQLENLIKKLRKASEGLNSTLKDHIMSHPALYDALNDPKNGDSAT--------KHLKQQASILGNIEKLKLLGPR----RCFVEFGAGKGKLSHWVDIALKDAEKV-----HFILVEKVTTRFKVDGKHRKKNSVFERLQIDIQHLCLNKIPVLREGKLPVVGIGKHLCGVATDLALRCLVETYAASFEERNEEPLAKRIKNDKTEKEINTLAKEGNEKNVPEKWTPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMQKTSFEASNITTKRKDNQNDDSEEHDEGGYRVTDDSSESLPGLLTVEEKKKIGHLCKLLIDQGRIQYLQQKGF---NPALQYYTDPLVSLENVLLTALPIHSSP 476
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. TrEMBL
Match: G1U3B6 (tRNA methyltransferase 13 homolog OS=Oryctolagus cuniculus OX=9986 GN=TRMT13 PE=4 SV=1)

HSP 1 Score: 223.016 bits (567), Expect = 1.057e-63
Identity = 151/468 (32.26%), Postives = 233/468 (49.79%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNV-------LAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKH-KKGPKFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCLKNWMDKEC-----------------------LSKE---NIK----TRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATC----------------------------GDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGR-KYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C +FV +K R+CR +      FC EH+     EN+ +R++CP+D KH+VYE +L +HLK CNA       F+ + IN+G     E   +++ ++ ++ ++++ +I  + +  + +       +     ++D     N G++++        KH  Q A+++ N+ K K+L         F+EFGAG+G  SH+++ ++  A  V      FIL+++   R + D KH KK   FER+ +DI HL LNK+  ++  ++ VV   KHLCG ATDL LRCL       C                       L+KE   NI     T + GIVIALCCHH+C+W+ Y+ K + R LGL + +FH    MS WATC                            G +R TD   + L     + EKK+IG LCK ++D GR KY  +K F   +  ++ Y D  V+LEN  L
Sbjct:   19 CGYFVEKKKRFCRMVVAAGKRFCGEHAGAAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNAREKPKPDFFIQDINAGLTDETEILEQLVPISSLSEEQLENLIKKLRKASEGLNSTLKHHIMSHPALHDALNDPNNGDSAT--------KHLKQQASILGNIEKLKLLGPR----RCFVEFGAGKGKLSHWVDIALKDAEKV-----HFILVEKGTTRFKVDGKHRKKNSVFERLQIDIQHLCLNKIPVLREGKLPVVGIGKHLCGVATDLALRCLIETYAASCEERNEEPLAKRIKNDKTEKEINTLAKERNENIVPEKWTPVAGIVIALCCHHRCDWRHYVGKEYFRTLGLGAVEFHYFQRMSSWATCGMRKTSLETSTMTTQPKGNQKDDEEHDDGGYRITDDSADSLPGLLTVEEKKKIGHLCKLLIDQGRVKYLQQKGF---SPALQYYTDPLVSLENVLL 466
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Cavefish
Match: trmt13 (tRNA methyltransferase 13 homolog [Source:NCBI gene;Acc:103035609])

HSP 1 Score: 200.29 bits (508), Expect = 8.968e-59
Identity = 143/461 (31.02%), Postives = 235/461 (50.98%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP-FYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIY----DINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKGPK-FERILMDISHLNLNKVETVKNK--RIFVVSKHLCGTATDLTLRCL--KNWMDKEC-----------LSKENIKT----RLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCG--------------DFRKTDTRFEE-----------------------LLNANGITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            C F+V +K RYC+ +      FC EH+ D   ++  +R+ CP+D KH+V+E  L +HLK CN+   K KP +Y + IN+GS + EED    + + +   +E+ ++I  +    K +  K D        ++   N  +  +F +     KH  Q A+++ NM   ++L         ++EFGAG+G  SH++  ++  A      ++ F+L++R   R + D KHK     F+R+ +DI HL+L KV  ++ K   +  V KHLCG ATDLTLRCL   N  D++C            S+E+ K     ++ G+ IA+CCHH+C+W+ Y+ K + RE GL  ++F     MS WATCG              + R+TD + ++                       L +A    E+++IG LCK ++D GR +++++    +N+    Y  + V+LEN  L
Sbjct:   17 CAFYVIKKKRYCKMVIGRGKSFCGEHA-DADKDSERKRIPCPLDPKHTVFEDSLAKHLKKCNSK-EKPKPVYYVKDINAGSVNEEEDVISEVSIAERTKEELDDLIGKLKTALKGLNIKPDSSILSHPALHEALNDPKNGNFAF-----KHLKQQASILGNMEALELLGPG----RCYVEFGAGKGKLSHWIHVAIEQAK-----DIHFLLVERSSTRFKVDGKHKNTDAIFDRLQVDIQHLDLRKVPFLREKGLPVIAVGKHLCGAATDLTLRCLFEHNLKDQDCDPPTKRVKLNEGSEEDTKPGEELKVSGVAIAVCCHHRCDWRHYVGKQFFRERGLGVREFDAFQRMSSWATCGMSRVGQGHKNLKQEEVRRTDEKQQKEEDVEEEEDEAEHEGSSETIPDNLNSAVSAEEREQIGRLCKTLIDQGRLHYLQQRGFKSNLSY--YTSRDVSLENVLL 459
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Sea Lamprey
Match: trmt13 (tRNA methyltransferase 13 homolog [Source:ZFIN;Acc:ZDB-GENE-050327-19])

HSP 1 Score: 217.624 bits (553), Expect = 8.377e-66
Identity = 146/474 (30.80%), Postives = 237/474 (50.00%), Query Frame = 2 
Query:   62 ESNDANVCKFFVARKNRYCRGMTKNSNEFCPEHSIDNHS----ENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKP-FYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTG---EASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKGP-KFERILMDISHLNLNKVETVKNKRIFVVS--KHLCGTATDLTLRCLKNWMDK---------------ECLSKENIKTRLK---GIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTD----------TRFEELLNANGI-----------------------------TEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            +S     C FFVARK RYC+         C EH+  + +     N  RR++CP+D+KH+VYE  L +HLK CNA   K+KP +Y   IN G +       +I+ L+ ++A+     +   ++++ + L + + + ++ V ++     E +       + KH  Q A+++ +++   +L     +  +  E GAGRG  SH+L R++  A+      ++F+L++R   R + D KH++G   F R+L+DI HL+L KV  +++K   VV+  KHLCG ATDL LRCL   + +               E   +   +T      GI I LCCHH+C+W +Y+ K +    GL  K+F L+  MS WATCG  R TD          TR E      G+                              E++++G LCKR++D GR  ++ +E+GLT  +++ Y++   T+EN  L
Sbjct:   12 QSPAPGCCAFFVARKRRYCKMSVAAGRALCGEHAACSGTGAPVANERRRIVCPLDSKHTVYEDVLEKHLKKCNAR-EKSKPAYYVRDINCGENDDLPSKEQIVALSSLSAE-EMSALISKVQVKSDGLDRAEAVLELRVLSHPALQQELTDPSNGKSALKHLQQQASIVGHLSTYGLL----AHKSVTHECGAGRGKLSHWLWRALPGATR----GVSFLLVERCSTRFKVDGKHQEGDVDFRRLLIDIQHLHLGKVPQLQDKGTSVVAIGKHLCGAATDLALRCLMETLPRHGTRAAAPGLAACGEEAPGQAPCETGTGPTLGIAITLCCHHRCSWPAYVGKEYFCSQGLGPKEFDLIQRMSSWATCGWRRPTDQVPDNGNEDATREERASRQGGVEWHAEEEMEAIDHAAPCQAEDQISYGRSRAEREQLGRLCKRVLDEGRVRYL-REWGLT-ARLQRYVEAGTTVENVLL 473
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Yeast
Match: TRM13 (2'-O-methyltransferase; responsible for modification of tRNA at position 4; C-terminal domain has similarity to Rossmann-fold (RFM) superfamily of RNA methyltransferases [Source:SGD;Acc:S000005485])

HSP 1 Score: 155.992 bits (393), Expect = 5.867e-43
Identity = 132/472 (27.97%), Postives = 223/472 (47.25%), Query Frame = 2 
Query:   83 CKFFVARKNRYCRGMTKNS-NEFCPEH----------SIDN----HSENSMRRVICPVDNKHSVYEHKLIQHLKVCN----ANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD-KHTFQYANLIENM------NKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSM-SCASSVPLDNL-----TFILIDRQGVRNRYDAKHKKG---------------PKFERILMDISHLNLNKV--ETVKNKRIFV-VSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQ----------FHLMTMMSGWATCGDFRKTDTRFEELLNAN-----------GITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFV 1285
            C++F+ +K R C GMT++S N +C EH           + N     +E    RV CP+D  H+V+  +L +HLK CN    +++   KP+Y    N  +              D+ A+ + + I L+ ++ +     +  +  +N   N   +     Q+ S+ KH  Q ++LIEN+       + + LN        F+EFG GR  FS ++   + +  +S+P ++       F+LIDR   R ++D K K                 P  +RI +DI  L ++ +   T  +   +V +SKHLCG ATDLTLRC+ N              +LK I IA+CC H C++  Y+N+S++  L    +           F ++T +  W TCG  RK  T   +++N              I E++ IGL+ +R++D GR  +++++F   N ++  Y++  V+LEN A+ V
Sbjct:   21 CEYFMEKKKRRC-GMTRSSQNLYCSEHLNLMKKAANSQVHNKNGSEAEKERERVPCPLDPNHTVWADQLKKHLKKCNKTKLSHLNDDKPYYEPGYNGENGLLSSSVKI-----DITAEHLVQSIELLYKVFEGESMDELPLRQLN---NKLMSLKRFPQLPSNTKHAVQQSSLIENLVDAGAFERPESLN--------FIEFGCGRAEFSRYVSLYLLTQLTSLPAEHSGSNSNEFVLIDRATNRMKFDKKIKDDFSEIKSNSPSKPISCPSIKRIKIDIRDLKMDPILKSTPGDDIQYVCISKHLCGVATDLTLRCIGNSSILHGDDNNGCNPKLKAICIAMCCRHVCDYGDYVNRSYVTSLVEKYRAHGSILTYETFFRVLTKLCSWGTCG--RKPGTAITDIVNVVESFEGAEPYTITIKERENIGLMARRVIDEGRLVYVKEKFTEFNAELIRYVESDVSLENVAMLV 473
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Nematostella
Match: EDO46123 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR85])

HSP 1 Score: 228.794 bits (582), Expect = 3.403e-70
Identity = 156/465 (33.55%), Postives = 240/465 (51.61%), Query Frame = 2 
Query:   50 TDMNESNDANV-CKFFVARKNRYCRGMTKNSNEFCPEH-SIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGI----YDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKG---PKFERILMDISHLNLNKVETV--KNKRIFVVSKHLCGTATD--LTLRCLKNWM--------DKECLSKENIKTRLK---------GIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDTRFEELLNAN----------------------GITEKKEIGLLCKRIMDLGRKYFI-EKEFGLTNVQIKPYIDQSVTLENCALFV 1285
             D  ES    + C F+V RKNRYC+ +     ++C EH  +   + ++ +R++CP+D KHSVYE +L  HLK CN        +Y++ INSG    +    E + L+    D I ++I+ + +       KD+ +    + ++  A   E S   Y     KH  Q A+L+ NM +  +L        ++LEFGAG+G  SH+++++          N+ ++LIDR   R ++D+ HK+G   P F+R+L+DI HLNL ++  +  K +RI  VSKHLCGTAT   LTLRCL + +        D    S++    R K         GIV+ALCCHH+C W  Y+ + ++  LG+  ++FHL+  MS WATCG  R      +E  + N                       I +++EIG  CKR++D GR +++ EK F   N  +  Y+D SV+LEN  L  
Sbjct:    2 ADEQESQPTRITCGFYVKRKNRYCKMIVGKGKKYCGEHMHLSGENGDNRKRILCPLDPKHSVYEDQLKNHLKRCNVKKKTDVVYYAKNINSGIVDYKPSSEEKIPLSSFPQDCISKVIHKLKK-----FFKDNNLEVMPHIMSHDAFKAEMSQENYGPSVHKHLKQQASLVGNMERLGLLQPD----TVYLEFGAGKGKLSHWVQQAHPEGG-----NVEYVLIDRASNRYKFDSCHKRGDNGPDFKRVLLDIEHLNLGELPHLGDKTRRIVAVSKHLCGTATGRYLTLRCLLDTLHGSSATEPDSTLKSEQKDAKRRKLDAAGPSVIGIVVALCCHHQCYWPHYVGRPFLESLGITPQEFHLLCCMSSWATCG-MRPPQGSSKEAEHCNTDESGETDDDNGVDGSDKGLGLSIADREEIGRQCKRLLDAGRVWYLREKGF---NTSLAYYVDSSVSLENVVLLA 448
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Medaka
Match: trmt13 (tRNA methyltransferase 13 homolog [Source:NCBI gene;Acc:101161965])

HSP 1 Score: 168.703 bits (426), Expect = 6.492e-47
Identity = 131/457 (28.67%), Postives = 213/457 (46.61%), Query Frame = 2 
Query:   77 NVCKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNA-NIPKTKPFYSEKINXXXXXX---XXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSD---KHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVP-LDNLTFILIDRQGVRNRYDAKHK-KGPKFERILMDISHLNLNKVETVKNKR--IFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLK-------------------------GIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCG------DF--------RKTDTRFEELLNANGI------TEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
            N C FF+ RK R+C+ M      FC EH+    S    R  IC      +V E KL +HLK CN+   PK   F    ++   ++          I+ L       ++++      ++  V        + N  ++       V     D   KH  Q A+++ ++++  +L         F+EFGAGRG  SH++  ++     +   ++L  +L++R  +R + D KH+  G +FER+ +DI HL+L+KV  +++K+  +  V KHLCG ATDL LRCL           E  + RLK                         G+ +ALCCHH+C W+ ++ + +  E GL + +F     MS WATCG      D+         + +   E L   + +       E+++IG LCKR++D GR +F++ + G ++ ++  Y DQ VTLEN  L
Sbjct:   10 NRCNFFLERKKRFCKMMVGKGQRFCGEHANAVSSRADAR--IC------TVAEDKLEKHLKKCNSRQKPKPVGFSPPSLHPSINTFNHFSIYYPSIIHLWSELELLLEKLKKASEGLQCEV--------EDNFLSHPALQEELVNPKNGDPAHKHLKQQASILGHLDELGLLR----RGRCFVEFGAGRGKLSHWIHEALKNNGDLKGSEDLQLLLVERSSIRFKVDGKHQDAGVQFERLQVDIEHLDLSKVPLLQDKKFPLVGVGKHLCGAATDLALRCLLETSRLRDPETEPPQKRLKPSEPAAEATPGDSGACSGASVSPVLGLAVALCCHHRCEWRHFVGRQFFLERGLGAAEFSAFCRMSSWATCGVRAANQDYSSHHSTNQERAEEEHEPLDETDTMNKFLSAVEREKIGRLCKRLIDSGRCHFLKSQ-GFSS-RLTCYTDQGVTLENVLL 444
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Medaka
Match: trmt13 (tRNA methyltransferase 13 homolog [Source:NCBI gene;Acc:101161965])

HSP 1 Score: 165.236 bits (417), Expect = 6.381e-46
Identity = 126/451 (27.94%), Postives = 205/451 (45.45%), Query Frame = 2 
Query:   74 ANVCKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVP-LDNLTFILIDRQGVRNRYDAKHK-KGPKFERILMDISHLNLNKVETVKNKR--IFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLK-------------------------GIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCG------DF--------RKTDTRFEELLNANGI------TEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCAL 1279
             N C FF+ RK R+C+ M      FC EH+    S    R  IC      +V E KL +HLK CN+   K KP      +        +   I   + ++                        ++ +N   +      F+     +   F  A+++ ++++  +L         F+EFGAGRG  SH++  ++     +   ++L  +L++R  +R + D KH+  G +FER+ +DI HL+L+KV  +++K+  +  V KHLCG ATDL LRCL           E  + RLK                         G+ +ALCCHH+C W+ ++ + +  E GL + +F     MS WATCG      D+         + +   E L   + +       E+++IG LCKR++D GR +F++ + G ++ ++  Y DQ VTLEN  L
Sbjct:    9 PNRCNFFLERKKRFCKMMVGKGQRFCGEHANAVSSRADAR--IC------TVAEDKLEKHLKKCNSRQ-KPKPVGFSPPSLHPSINTFNHFSIYYPSIIH------------------------LFFLNCPTSPSPIQIFLCPF-INLSEFSKASILGHLDELGLLR----RGRCFVEFGAGRGKLSHWIHEALKNNGDLKGSEDLQLLLVERSSIRFKVDGKHQDAGVQFERLQVDIEHLDLSKVPLLQDKKFPLVGVGKHLCGAATDLALRCLLETSRLRDPETEPPQKRLKPSEPAAEATPGDSGACSGASVSPVLGLAVALCCHHRCEWRHFVGRQFFLERGLGAAEFSAFCRMSSWATCGVRAANQDYSSHHSTNQERAEEEHEPLDETDTMNKFLSAVEREKIGRLCKRLIDSGRCHFLKSQ-GFSS-RLTCYTDQGVTLENVLL 419
[Close]
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Planmine SMEST
Match: SMESG000014287.1 (SMESG000014287.1)

HSP 1 Score: 795.038 bits (2052), Expect = 0.000e+0
Identity = 409/411 (99.51%), Postives = 411/411 (100.00%), Query Frame = 2 
Query:   56 MNESNDANVCKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINXXXXXXXXXXXXILKLNDVNADXXXXXXXXXXXXRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKGPKFERILMDISHLNLNKVETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDTRFEELLNANGITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFVD 1288
            MNESNDANVCKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINSGSDSGEEDDSEILKLNDVNADEIKEIINLII+IRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKGPKFERILMDISHLNLNKVETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDTRFEELLNANGITEKKEIGLLCKRI+DLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFVD
Sbjct:    1 MNESNDANVCKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVICPVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINSGSDSGEEDDSEILKLNDVNADEIKEIINLIIKIRKNVLAKDDGIYDINVTANTGEASSFVYQMKSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSMSCASSVPLDNLTFILIDRQGVRNRYDAKHKKGPKFERILMDISHLNLNKVETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVIALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDTRFEELLNANGITEKKEIGLLCKRILDLGRKYFIEKEFGLTNVQIKPYIDQSVTLENCALFVD 411
The following BLAST results are available for this feature:
BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
TRMT131.493e-6231.56tRNA methyltransferase 13 homolog [Source:HGNC Sym... [more]
TRMT135.120e-1542.31tRNA methyltransferase 13 homolog [Source:HGNC Sym... [more]
TRMT132.141e-1438.96tRNA methyltransferase 13 homolog [Source:HGNC Sym... [more]
TRMT132.341e-947.37tRNA methyltransferase 13 homolog [Source:HGNC Sym... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Y49A3A.33.316e-2724.14pep chromosome:WBcel235:V:14354410:14355754:1 gene... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG180483.182e-4829.06gene:FBgn0037435 transcript:FBtr0081712[more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trmt132.141e-6033.99tRNA methyltransferase 13 homolog [Source:ZFIN;Acc... [more]
trmt132.644e-6033.99tRNA methyltransferase 13 homolog [Source:ZFIN;Acc... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
trmt132.581e-5730.40tRNA methyltransferase 13 homolog (S. cerevisiae) ... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Trmt131.805e-6331.03tRNA methyltransferase 13 [Source:MGI Symbol;Acc:M... [more]
Trmt135.538e-3631.48tRNA methyltransferase 13 [Source:MGI Symbol;Acc:M... [more]
Trmt134.949e-1540.26tRNA methyltransferase 13 [Source:MGI Symbol;Acc:M... [more]
Trmt132.682e-948.98tRNA methyltransferase 13 [Source:MGI Symbol;Acc:M... [more]
Trmt132.113e-724.43tRNA methyltransferase 13 [Source:MGI Symbol;Acc:M... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8BYH3|TRM13_MOUSE1.262e-6231.03tRNA:m(4)X modification enzyme TRM13 homolog OS=Mu... [more]
sp|Q9NUP7|TRM13_HUMAN7.169e-6231.56tRNA:m(4)X modification enzyme TRM13 homolog OS=Ho... [more]
sp|A7TSF4|TRM13_VANPO8.848e-5031.53tRNA:m(4)X modification enzyme TRM13 OS=Vanderwalt... [more]
sp|Q12383|TRM13_YEAST4.074e-4127.97tRNA:m(4)X modification enzyme TRM13 OS=Saccharomy... [more]
sp|A3LXS6|TRM13_PICST3.397e-3728.44tRNA:m(4)X modification enzyme TRM13 OS=Schefferso... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2B4S0211.203e-6734.65tRNA:m(4)X modification enzyme TRM13-like OS=Stylo... [more]
A0A1Y1XRP42.254e-6635.12DUF715-domain-containing protein OS=Basidiobolus m... [more]
A7RR852.461e-6633.55Predicted protein OS=Nematostella vectensis OX=453... [more]
I3ML365.868e-6431.80tRNA methyltransferase 13 homolog OS=Ictidomys tri... [more]
G1U3B61.057e-6332.26tRNA methyltransferase 13 homolog OS=Oryctolagus c... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
trmt138.968e-5931.02tRNA methyltransferase 13 homolog [Source:NCBI gen... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
trmt138.377e-6630.80tRNA methyltransferase 13 homolog [Source:ZFIN;Acc... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
TRM135.867e-4327.972'-O-methyltransferase; responsible for modificati... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO461233.403e-7033.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trmt136.492e-4728.67tRNA methyltransferase 13 homolog [Source:NCBI gen... [more]
trmt136.381e-4627.94tRNA methyltransferase 13 homolog [Source:NCBI gen... [more]
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BLAST of tRNA:m(4)X modification enzyme TRM13-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000014287.10.000e+099.51SMESG000014287.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029653 ID=SMED30029653|Name=tRNA:m(4)X modification enzyme TRM13-like|organism=Schmidtea mediterranea sexual|type=transcript|length=1349bp
ATTCATCCAAAACTTTGTTTAAATATTGAATATTTGTGTATTTGGTTATA
CTGACATGAACGAGTCCAATGATGCTAATGTATGCAAATTTTTTGTTGCT
CGCAAAAACCGGTATTGTAGAGGAATGACTAAAAATTCAAACGAATTCTG
CCCTGAGCATTCAATTGATAACCATTCAGAAAATTCTATGAGACGTGTAA
TTTGCCCAGTTGATAATAAACATTCTGTCTATGAACATAAATTAATTCAA
CATTTAAAAGTTTGCAATGCAAACATTCCGAAAACCAAACCATTTTATTC
GGAAAAAATCAACTCTGGCTCAGATTCTGGGGAAGAAGATGATTCCGAAA
TTTTAAAACTGAATGATGTAAACGCGGACGAAATTAAAGAAATAATTAAT
CTGATTATCGAAATTCGAAAAAATGTTCTTGCTAAAGATGATGGAATATA
CGACATAAACGTAACTGCTAACACAGGTGAAGCCAGCTCGTTTGTGTATC
AAATGAAAAGTGATAAGCACACCTTTCAATATGCAAATCTAATTGAAAAT
ATGAATAAGAGGAAAATGTTGAATGTGTCACCAATCAACACAGATATTTT
CCTGGAATTTGGCGCAGGAAGAGGAGGATTTTCACATTTTCTAGAAAGAT
CTATGTCTTGTGCTAGTAGTGTACCATTAGACAATTTGACTTTTATTCTA
ATCGACCGGCAAGGTGTTCGTAATCGATATGATGCTAAACATAAAAAGGG
ACCTAAGTTTGAGAGAATTCTCATGGATATATCCCATCTAAATTTGAACA
AAGTAGAAACTGTCAAGAACAAGAGGATATTTGTTGTTTCCAAGCATTTA
TGTGGAACTGCAACAGATTTAACACTTCGGTGCTTGAAGAACTGGATGGA
CAAGGAATGCTTGTCTAAAGAAAATATCAAAACTCGTTTAAAGGGTATTG
TTATAGCTTTGTGTTGTCATCACAAATGTAATTGGAAAAGTTACATTAAC
AAATCCTGGATACGAGAATTGGGATTGAACTCAAAACAATTCCATTTGAT
GACAATGATGTCTGGTTGGGCTACTTGCGGAGATTTCAGGAAAACTGACA
CGAGATTTGAAGAATTACTGAACGCAAATGGAATCACAGAAAAAAAAGAA
ATCGGCTTGCTGTGTAAACGAATTATGGATTTAGGTCGAAAATATTTCAT
AGAAAAAGAATTTGGATTGACTAATGTTCAAATCAAACCTTATATTGACC
AGTCAGTCACATTGGAAAATTGTGCACTGTTTGTTGATTAAATATATTCG
ACTTCCTTATGTTTTGACTTAGTTCAATTATTGGATGAAATGTGATGCC
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protein sequence of SMED30029653-orf-1

>SMED30029653-orf-1 ID=SMED30029653-orf-1|Name=SMED30029653-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=412bp
MNESNDANVCKFFVARKNRYCRGMTKNSNEFCPEHSIDNHSENSMRRVIC
PVDNKHSVYEHKLIQHLKVCNANIPKTKPFYSEKINSGSDSGEEDDSEIL
KLNDVNADEIKEIINLIIEIRKNVLAKDDGIYDINVTANTGEASSFVYQM
KSDKHTFQYANLIENMNKRKMLNVSPINTDIFLEFGAGRGGFSHFLERSM
SCASSVPLDNLTFILIDRQGVRNRYDAKHKKGPKFERILMDISHLNLNKV
ETVKNKRIFVVSKHLCGTATDLTLRCLKNWMDKECLSKENIKTRLKGIVI
ALCCHHKCNWKSYINKSWIRELGLNSKQFHLMTMMSGWATCGDFRKTDTR
FEELLNANGITEKKEIGLLCKRIMDLGRKYFIEKEFGLTNVQIKPYIDQS
VTLENCALFVD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0030488tRNA methylation
GO:0008033tRNA processing
GO:0032259methylation
Vocabulary: INTERPRO
TermDefinition
IPR039044Trm13
IPR022776TRM13/UPF0224_CHHC_Znf_dom
IPR021721Znf_CCCH-type_TRM13
IPR007871Methyltransferase_TRM13
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity
GO:0016740transferase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR021721Zinc finger, CCCH-type, TRM13PFAMPF11722zf-TRM13_CCCHcoord: 10..35
e-value: 4.7E-7
score: 29.5
IPR022776TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domainPFAMPF05253zf-U11-48Kcoord: 47..71
e-value: 4.3E-6
score: 26.5
IPR022776TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domainPROSITEPS51800ZF_CHHC_U11_48Kcoord: 47..74
score: 13.523
IPR007871Methyltransferase TRM13PFAMPF05206TRM13coord: 158..410
e-value: 2.6E-67
score: 227.1
NoneNo IPR availablePANTHERPTHR12998:SF0TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOGcoord: 3..409
IPR039044tRNA:m(4)X modification enzyme Trm13PANTHERPTHR12998UNCHARACTERIZEDcoord: 3..409