2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

Overview
Name2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
Smed IDSMED30029650
Length (bp)1338
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (SMED30029650) t-SNE clustered cells

Violin plots show distribution of expression levels for 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (SMED30029650) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (SMED30029650) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (SMED30029650) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029650

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30029650h1SMcG0020416 dd_Smed_v4_2949_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30029650h1SMcG0020416 dd_Smed_v4_2949_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30029650h1SMcG0020416 dd_Smed_v4_2949_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Human
Match: BCKDHB (branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987])

HSP 1 Score: 451.44 bits (1160), Expect = 4.205e-157
Identity = 227/340 (66.76%), Postives = 279/340 (82.06%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +  P E G+  KMNL ++V ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR+P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR A E+VPI+ Y  PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D + +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   53 HFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Human
Match: BCKDHB (branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987])

HSP 1 Score: 451.44 bits (1160), Expect = 4.205e-157
Identity = 227/340 (66.76%), Postives = 279/340 (82.06%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +  P E G+  KMNL ++V ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR+P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR A E+VPI+ Y  PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D + +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   53 HFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Human
Match: BCKDHB (branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987])

HSP 1 Score: 192.2 bits (487), Expect = 2.389e-58
Identity = 110/160 (68.75%), Postives = 130/160 (81.25%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKV 617
            HF +  +  P E G+  KMNL ++V ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR+P G VGHG +YHSQS EAF+ H PG+K+
Sbjct:   53 HFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKI 212
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Human
Match: PDHB (pyruvate dehydrogenase E1 beta subunit [Source:HGNC Symbol;Acc:HGNC:8808])

HSP 1 Score: 169.859 bits (429), Expect = 5.319e-48
Identity = 128/358 (35.75%), Postives = 182/358 (50.84%), Query Frame = 3 
Query:  117 VRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKE--------PLSKADIVMEGKDVTMIGWGTQV-HVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            +R  SG   +     AP+ L    ++ + +A+N  +D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP+SE G  G  +G A AG   I E    ++   A DQ++N AAK  Y SG       +  R P GA       HSQ   A+Y H PG+KVV P     AKGL+ S + DNNP +  E +++Y      VP +F  E        P+ KA I  +G  +T++     V H L+  A LS  K  V CEVI+++T+ P D + +  SV KT  LV         G GAEI A + E   FN L+AP  RVTG D P PY  I E   +P +   + A+K  +
Sbjct:   12 LREVSGLLKRRFHWTAPAAL----QVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGG-LQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY-----GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS--KEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL 357
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Human
Match: PDHB (pyruvate dehydrogenase E1 beta subunit [Source:HGNC Symbol;Acc:HGNC:8808])

HSP 1 Score: 167.933 bits (424), Expect = 1.498e-47
Identity = 122/329 (37.08%), Postives = 170/329 (51.67%), Query Frame = 3 
Query:  204 EAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKE--------PLSKADIVMEGKDVTMIGWGTQV-HVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            +A+N  +D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP+SE G  G  +G A AG   I E    ++   A DQ++N AAK  Y SG       +  R P GA       HSQ   A+Y H PG+KVV P     AKGL+ S + DNNP +  E +++Y      VP +F  E        P+ KA I  +G  +T++     V H L+  A LS  K  V CEVI+++T+ P D + +  SV KT  LV         G GAEI A + E   FN L+AP  RVTG D P PY  I E   +P +   + A+K  +
Sbjct:   19 DAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGG-LQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY-----GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS--KEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL 339
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Celegans
Match: bckd-1B (Branched Chain Keto acid Dehydrogenase e1 (E1) subunit [Source:UniProtKB/TrEMBL;Acc:Q93619])

HSP 1 Score: 424.091 bits (1089), Expect = 3.030e-147
Identity = 225/367 (61.31%), Postives = 282/367 (76.84%), Query Frame = 3 
Query:   66 MIRKVISRLVKPNFRIWVRSYSGPHFKYV-SEKAPSELG--ECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            M  + +S   K   RI  ++    HF +  S   P+ L   E TKMNL ++VN ++ + +E D SA++FGEDV+FGGVFRC+  L+ K+GKDR+FNTPL EQGI GFGIGVAAAGA AIAEIQF DYI PA+DQ+VNEAAK RYRSGNQF+CG LT+RT  GAVGHG +YHSQS EA +TH PG+K+V+PRGP++AKGLLLSC+ D NPCIFFEPKILYR A EDVP   Y  PL +A+ V  GKD+T++ WGTQVHV  E A+L+  K +   EVIDLQT+ PWDED V ESV+KTGRL+++HEAP++SGFGAEIA++VQ+ CF NLE+PI RV GFDTPFP+++EPFYLP + R  +A+K  + Y
Sbjct:    1 MSSRAVSLFSKCGSRI-SQTRGKAHFTFQPSTTLPAGLENLEKTKMNLMQSVNEAMRIAMETDDSAVLFGEDVAFGGVFRCSLDLQKKFGKDRVFNTPLCEQGIAGFGIGVAAAGATAIAEIQFGDYIFPAYDQLVNEAAKFRYRSGNQFDCGKLTVRTTWGAVGHGALYHSQSPEANFTHTPGLKLVVPRGPVQAKGLLLSCIRDPNPCIFFEPKILYRLASEDVPTGDYTIPLGQAETVRSGKDLTLVAWGTQVHVALEAAQLAKEKLNADVEVIDLQTIQPWDEDHVVESVQKTGRLIVTHEAPISSGFGAEIASTVQKRCFLNLESPIDRVAGFDTPFPHVHEPFYLPTVHRVFDAIKKSVNY 366
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Celegans
Match: pdhb-1 (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:O44451])

HSP 1 Score: 171.785 bits (434), Expect = 2.470e-49
Identity = 121/339 (35.69%), Postives = 181/339 (53.39%), Query Frame = 3 
Query:  147 YVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAV---EDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVK 1142
            +V+  A +     + M + +A+N ++D  +++D    + GE+V+ + G ++ +KGL  K+G  R+ +TP++E G  G  +G A AG   I E    ++   A DQI+N AAK  Y S  +     +  R P GA       HSQ   A+Y H PG+KVV P     AKGLL + + D+NP +F E +ILY  +    ++V    +  P+ KA I   G  VT++ +   V    E AK  L    VS EVI+L++L P+D + + +SV KT  LV        +G G+EIAA V E+  F+ L+AP+ RVTG D P PY    E   LP     ++AVK
Sbjct:   10 FVARLAGTSTRAASTMTVRDALNQAMDEEIKRDDRVFLMGEEVAQYDGAYKISKGLWKKHGDKRVVDTPITEMGFAGIAVGAAFAGLRPICEFMTFNFSMQAIDQIINSAAKTYYMSAGRVPVP-IVFRGPNGAAAGVAAQHSQDFSAWYAHCPGLKVVCPYSAEDAKGLLKAAIRDDNPVVFLENEILYGQSFPVGDEVLSDDFVVPIGKAKIERAGDHVTIVSYSRGVEFSLEAAK-QLEAIGVSAEVINLRSLRPFDFESIRQSVHKTHHLVSVETGWPFAGIGSEIAAQVMESDVFDQLDAPLLRVTGVDVPMPYTQTLEAAALPTAEHVVKAVK 346
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Fly
Match: CG17691 (gene:FBgn0039993 transcript:FBtr0113761)

HSP 1 Score: 429.483 bits (1103), Expect = 2.592e-149
Identity = 215/357 (60.22%), Postives = 276/357 (77.31%), Query Frame = 3 
Query:   93 VKPNFR--IWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            V+ N R  +W RS    HF Y     P+ +G   +MN+  A+NN++DL L+++ SA++FGEDV FGGVFRC+  L+DKYG  R+FNTPL EQGI GF IGVA  GA AIAEIQFADYI P+FDQIVNEAAK RYRSG  F+CG LT R PCGAVGHG +YHSQS EA++ H PG++VV+PRGPIKAKGL+L+C+ D NPCI FEPK LYR AVE+VP ++Y   L KADI+  GKDVT+IGWGTQVHVL EVA+++ +  ++ CEVIDL ++ PWD   +  S KKTGR++I+HEAPLT GFG+E+A+ +QE CF +LEAP++RV G+DTPFP+++EPFY+PD  RCL A+  ++ +
Sbjct:   16 VRSNLRWPLWTRS----HFTYY----PTRMGTGKRMNMFNAINNAMDLALDENKSALLFGEDVGFGGVFRCSVNLRDKYGSQRVFNTPLCEQGIAGFAIGVANTGATAIAEIQFADYIFPSFDQIVNEAAKYRYRSGGLFDCGSLTFRVPCGAVGHGALYHSQSPEAYFAHTPGLRVVVPRGPIKAKGLILACIRDPNPCIVFEPKTLYRAAVEEVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVAEIAKSTLNIDCEVIDLVSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSELASYIQEKCFLHLEAPVKRVAGWDTPFPHVFEPFYMPDKHRCLSAINDIVNF 364
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Fly
Match: CG17691 (gene:FBgn0039993 transcript:FBtr0302409)

HSP 1 Score: 429.483 bits (1103), Expect = 2.592e-149
Identity = 215/357 (60.22%), Postives = 276/357 (77.31%), Query Frame = 3 
Query:   93 VKPNFR--IWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            V+ N R  +W RS    HF Y     P+ +G   +MN+  A+NN++DL L+++ SA++FGEDV FGGVFRC+  L+DKYG  R+FNTPL EQGI GF IGVA  GA AIAEIQFADYI P+FDQIVNEAAK RYRSG  F+CG LT R PCGAVGHG +YHSQS EA++ H PG++VV+PRGPIKAKGL+L+C+ D NPCI FEPK LYR AVE+VP ++Y   L KADI+  GKDVT+IGWGTQVHVL EVA+++ +  ++ CEVIDL ++ PWD   +  S KKTGR++I+HEAPLT GFG+E+A+ +QE CF +LEAP++RV G+DTPFP+++EPFY+PD  RCL A+  ++ +
Sbjct:   16 VRSNLRWPLWTRS----HFTYY----PTRMGTGKRMNMFNAINNAMDLALDENKSALLFGEDVGFGGVFRCSVNLRDKYGSQRVFNTPLCEQGIAGFAIGVANTGATAIAEIQFADYIFPSFDQIVNEAAKYRYRSGGLFDCGSLTFRVPCGAVGHGALYHSQSPEAYFAHTPGLRVVVPRGPIKAKGLILACIRDPNPCIVFEPKTLYRAAVEEVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVAEIAKSTLNIDCEVIDLVSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSELASYIQEKCFLHLEAPVKRVAGWDTPFPHVFEPFYMPDKHRCLSAINDIVNF 364
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Fly
Match: Pdhb (gene:FBgn0039635 transcript:FBtr0085369)

HSP 1 Score: 170.244 bits (430), Expect = 2.062e-48
Identity = 112/328 (34.15%), Postives = 171/328 (52.13%), Query Frame = 3 
Query:  189 KMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGA---VEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQE-ACFFNLEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            +M + +A+N++LD  L +D    + GE+V+ + G ++ ++GL  KYG  R+ +TP++E G  G  +G A AG   + E    ++   A D I+N AAK  Y S    N   +  R P GA       HSQ   A+Y H PG+KV+ P     A+GLL S + D +P +F E +++Y  A    ++V  K +  P+ KA ++  GKD+T++     V     +A   L K  +  EVI+L+++ P D   ++ SV+KT  LV         G GAEI A + E   FF L+AP+ R  G D P PY    E   LP +   +EA   V+
Sbjct:   28 QMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKKYGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAGAVNVP-IVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDPVVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVET-SLLAAAELAKKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVL 353
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Fly
Match: Pdhb (gene:FBgn0039635 transcript:FBtr0085366)

HSP 1 Score: 170.244 bits (430), Expect = 2.062e-48
Identity = 112/328 (34.15%), Postives = 171/328 (52.13%), Query Frame = 3 
Query:  189 KMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGA---VEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQE-ACFFNLEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            +M + +A+N++LD  L +D    + GE+V+ + G ++ ++GL  KYG  R+ +TP++E G  G  +G A AG   + E    ++   A D I+N AAK  Y S    N   +  R P GA       HSQ   A+Y H PG+KV+ P     A+GLL S + D +P +F E +++Y  A    ++V  K +  P+ KA ++  GKD+T++     V     +A   L K  +  EVI+L+++ P D   ++ SV+KT  LV         G GAEI A + E   FF L+AP+ R  G D P PY    E   LP +   +EA   V+
Sbjct:   28 QMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKKYGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAGAVNVP-IVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDPVVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVET-SLLAAAELAKKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVL 353
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Fly
Match: CG17691 (gene:FBgn0039993 transcript:FBtr0302410)

HSP 1 Score: 97.4413 bits (241), Expect = 2.496e-24
Identity = 45/91 (49.45%), Postives = 62/91 (68.13%), Query Frame = 3 
Query:   93 VKPNFR--IWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSE 359
            V+ N R  +W RS    HF Y     P+ +G   +MN+  A+NN++DL L+++ SA++FGEDV FGGVFRC+  L+DKYG  R+FNTPL E
Sbjct:   16 VRSNLRWPLWTRS----HFTYY----PTRMGTGKRMNMFNAINNAMDLALDENKSALLFGEDVGFGGVFRCSVNLRDKYGSQRVFNTPLCE 98
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Zebrafish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 453.366 bits (1165), Expect = 7.660e-158
Identity = 229/340 (67.35%), Postives = 281/340 (82.65%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF Y  +  P++ G   KMNL ++V ++LD  L  D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG AAAGA AIAEIQFADYI PAFDQIVNEAAK RYRSGN ++CG LTIR+P G VGHG +YHSQS EAF+ H PG+KVV+PRGP++AKGLLLSC+ED NPCIFFEPKILYR AVE VP + Y  PLS+A+++ EG D+T++ WGTQ+HV++EVA ++  K  VSCE+IDLQT+ PWD++ V +SV KTGRL+ISHEAP+T GF AEI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C EAVK +I Y
Sbjct:   66 HFTYQPDPVPTQYGPTQKMNLFQSVTSALDNTLSIDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGAAAAGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGNMYDCGKLTIRSPWGCVGHGSLYHSQSPEAFFAHCPGLKVVVPRGPVQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPTEAYYIPLSQAEVLQEGSDLTLVAWGTQIHVMREVAAMAQEKLGVSCELIDLQTILPWDKETVCKSVMKTGRLLISHEAPVTGGFAAEISSAVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCFEAVKRMINY 405
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Zebrafish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 453.366 bits (1165), Expect = 7.660e-158
Identity = 229/340 (67.35%), Postives = 281/340 (82.65%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF Y  +  P++ G   KMNL ++V ++LD  L  D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG AAAGA AIAEIQFADYI PAFDQIVNEAAK RYRSGN ++CG LTIR+P G VGHG +YHSQS EAF+ H PG+KVV+PRGP++AKGLLLSC+ED NPCIFFEPKILYR AVE VP + Y  PLS+A+++ EG D+T++ WGTQ+HV++EVA ++  K  VSCE+IDLQT+ PWD++ V +SV KTGRL+ISHEAP+T GF AEI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C EAVK +I Y
Sbjct:   66 HFTYQPDPVPTQYGPTQKMNLFQSVTSALDNTLSIDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGAAAAGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGNMYDCGKLTIRSPWGCVGHGSLYHSQSPEAFFAHCPGLKVVVPRGPVQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPTEAYYIPLSQAEVLQEGSDLTLVAWGTQIHVMREVAAMAQEKLGVSCELIDLQTILPWDKETVCKSVMKTGRLLISHEAPVTGGFAAEISSAVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCFEAVKRMINY 405
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Zebrafish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 451.825 bits (1161), Expect = 1.481e-157
Identity = 229/340 (67.35%), Postives = 281/340 (82.65%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF Y  +  P++ G   KMNL ++V ++LD  L  D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG AAAGA AIAEIQFADYI PAFDQIVNEAAK RYRSGN ++CG LTIR+P G VGHG +YHSQS EAF+ H PG+KVV+PRGP++AKGLLLSC+ED NPCIFFEPKILYR AVE VP + Y  PLS+A+++ EG D+T++ WGTQ+HV++EVA ++  K  VSCE+IDLQT+ PWD++ V +SV KTGRL+ISHEAP+T GF AEI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C EAVK +I Y
Sbjct:   52 HFTYQPDPVPTQYGPTQKMNLFQSVTSALDNTLSIDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGAAAAGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGNMYDCGKLTIRSPWGCVGHGSLYHSQSPEAFFAHCPGLKVVVPRGPVQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPTEAYYIPLSQAEVLQEGSDLTLVAWGTQIHVMREVAAMAQEKLGVSCELIDLQTILPWDKETVCKSVMKTGRLLISHEAPVTGGFAAEISSAVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCFEAVKRMINY 391
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Zebrafish
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:ZFIN;Acc:ZDB-GENE-040426-2173])

HSP 1 Score: 166.777 bits (421), Expect = 4.323e-47
Identity = 114/330 (34.55%), Postives = 173/330 (52.42%), Query Frame = 3 
Query:  183 CTKMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYR---GAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
              ++ + +A+N ++D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP++E G  G  +G A AG   I E    ++   A DQ++N AAK  Y S        +  R P GA       HSQ   A+Y H PG+KV+ P     A+GLL + + D+NP +F E +++Y       E+V  K +  P+ KA I  +G  +T++     V +  + A + L K  + CEVI+L+++ P D D +  S+ KT  LV         G GAEI A + E   FN L+AP  RVTG D P PY  I E   +P I   + +VK  +
Sbjct:   30 AVQVTVRDALNQAMDEELERDERVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPITEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSAG-LQAVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVLSPWNSEDARGLLKAAIRDDNPVVFLENELMYGVPFEMSEEVQSKDFVIPIGKAKIERQGNHITLVSHSRMVGLCLDAAAV-LAKEGIECEVINLRSIRPLDADTIETSITKTNHLVTVEGGWPQFGVGAEILARIMEGPAFNYLDAPAVRVTGVDIPMPYAKILEDNSIPQIKDIIFSVKKTL 357
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Zebrafish
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:ZFIN;Acc:ZDB-GENE-040426-2173])

HSP 1 Score: 92.0485 bits (227), Expect = 3.448e-21
Identity = 59/168 (35.12%), Postives = 91/168 (54.17%), Query Frame = 3 
Query:  183 CTKMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNP 683
              ++ + +A+N ++D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP++E G  G  +G A AG   I E    ++   A DQ++N AAK  Y S        +  R P GA       HSQ   A+Y H PG+KV+ P     A+GLL + + D+NP
Sbjct:   30 AVQVTVRDALNQAMDEELERDERVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPITEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSAG-LQAVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVLSPWNSEDARGLLKAAIRDDNP 196
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Xenopus
Match: cela2a (chymotrypsin like elastase 2A [Source:Xenbase;Acc:XB-GENE-970278])

HSP 1 Score: 442.965 bits (1138), Expect = 1.191e-154
Identity = 223/329 (67.78%), Postives = 276/329 (83.89%), Query Frame = 3 
Query:  171 ELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            +LG   KMNL +++N++LD  L +D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIGVA AGA +IAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR PI+AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ Y  PLS+A+++ EG D+T++ WGTQVHV++EVA ++  K  +SCEVIDL+T+ PWD + V +SV KTGRL+ISHEAP+T GF +EI+A+VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   14 DLGTTQKMNLFQSINSALDNTLSRDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGVAVAGATSIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHAPGIKVVIPRSPIQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYYIPLSQAEVIQEGTDITLLSWGTQVHVIREVAVMAQEKLGLSCEVIDLRTILPWDVETVCKSVSKTGRLLISHEAPVTGGFASEISATVQEECFLNLEAPIARVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 342
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Xenopus
Match: cela2a (chymotrypsin like elastase 2A [Source:Xenbase;Acc:XB-GENE-970278])

HSP 1 Score: 441.039 bits (1133), Expect = 5.189e-154
Identity = 222/324 (68.52%), Postives = 274/324 (84.57%), Query Frame = 3 
Query:  186 TKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            TKMNL +++N++LD  L +D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIGVA AGA +IAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR PI+AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ Y  PLS+A+++ EG D+T++ WGTQVHV++EVA ++  K  +SCEVIDL+T+ PWD + V +SV KTGRL+ISHEAP+T GF +EI+A+VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   14 TKMNLFQSINSALDNTLSRDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGVAVAGATSIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHAPGIKVVIPRSPIQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYYIPLSQAEVIQEGTDITLLSWGTQVHVIREVAVMAQEKLGLSCEVIDLRTILPWDVETVCKSVSKTGRLLISHEAPVTGGFASEISATVQEECFLNLEAPIARVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 337
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Xenopus
Match: cela2a (chymotrypsin like elastase 2A [Source:Xenbase;Acc:XB-GENE-970278])

HSP 1 Score: 440.654 bits (1132), Expect = 1.219e-153
Identity = 222/327 (67.89%), Postives = 274/327 (83.79%), Query Frame = 3 
Query:  177 GECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            G   KMNL +++N++LD  L +D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIGVA AGA +IAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR PI+AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ Y  PLS+A+++ EG D+T++ WGTQVHV++EVA ++  K  +SCEVIDL+T+ PWD + V +SV KTGRL+ISHEAP+T GF +EI+A+VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   25 GTTQKMNLFQSINSALDNTLSRDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGVAVAGATSIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHAPGIKVVIPRSPIQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYYIPLSQAEVIQEGTDITLLSWGTQVHVIREVAVMAQEKLGLSCEVIDLRTILPWDVETVCKSVSKTGRLLISHEAPVTGGFASEISATVQEECFLNLEAPIARVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 351
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Xenopus
Match: cela2a (chymotrypsin like elastase 2A [Source:Xenbase;Acc:XB-GENE-970278])

HSP 1 Score: 440.654 bits (1132), Expect = 1.484e-153
Identity = 224/340 (65.88%), Postives = 280/340 (82.35%), Query Frame = 3 
Query:  153 SEKAPSELGEC-----TKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            + + P +L +C      KMNL +++N++LD  L +D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIGVA AGA +IAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR PI+AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ Y  PLS+A+++ EG D+T++ WGTQVHV++EVA ++  K  +SCEVIDL+T+ PWD + V +SV KTGRL+ISHEAP+T GF +EI+A+VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   12 ATRRPRDLFKCKTRTTQKMNLFQSINSALDNTLSRDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGVAVAGATSIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHAPGIKVVIPRSPIQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYYIPLSQAEVIQEGTDITLLSWGTQVHVIREVAVMAQEKLGLSCEVIDLRTILPWDVETVCKSVSKTGRLLISHEAPVTGGFASEISATVQEECFLNLEAPIARVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 351
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Xenopus
Match: cela2a (chymotrypsin like elastase 2A [Source:Xenbase;Acc:XB-GENE-970278])

HSP 1 Score: 437.187 bits (1123), Expect = 1.344e-152
Identity = 220/323 (68.11%), Postives = 272/323 (84.21%), Query Frame = 3 
Query:  189 KMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
             MNL +++N++LD  L +D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIGVA AGA +IAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR PI+AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ Y  PLS+A+++ EG D+T++ WGTQVHV++EVA ++  K  +SCEVIDL+T+ PWD + V +SV KTGRL+ISHEAP+T GF +EI+A+VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:    3 SMNLFQSINSALDNTLSRDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGVAVAGATSIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHAPGIKVVIPRSPIQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYYIPLSQAEVIQEGTDITLLSWGTQVHVIREVAVMAQEKLGLSCEVIDLRTILPWDVETVCKSVSKTGRLLISHEAPVTGGFASEISATVQEECFLNLEAPIARVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 325
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Mouse
Match: Bckdhb (branched chain ketoacid dehydrogenase E1, beta polypeptide [Source:MGI Symbol;Acc:MGI:88137])

HSP 1 Score: 447.973 bits (1151), Expect = 5.840e-156
Identity = 226/340 (66.47%), Postives = 278/340 (81.76%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +    + G+  KMNL +++ ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ YK PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D V +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   51 HFTFHPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 390
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Mouse
Match: Bckdhb (branched chain ketoacid dehydrogenase E1, beta polypeptide [Source:MGI Symbol;Acc:MGI:88137])

HSP 1 Score: 439.884 bits (1130), Expect = 8.847e-154
Identity = 222/322 (68.94%), Postives = 270/322 (83.85%), Query Frame = 3 
Query:  192 MNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            MNL +++ ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ YK PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D V +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:    1 MNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 322
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Mouse
Match: Bckdhb (branched chain ketoacid dehydrogenase E1, beta polypeptide [Source:MGI Symbol;Acc:MGI:88137])

HSP 1 Score: 439.884 bits (1130), Expect = 8.847e-154
Identity = 222/322 (68.94%), Postives = 270/322 (83.85%), Query Frame = 3 
Query:  192 MNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            MNL +++ ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ YK PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D V +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:    1 MNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 322
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Mouse
Match: Pdhb (pyruvate dehydrogenase (lipoamide) beta [Source:MGI Symbol;Acc:MGI:1915513])

HSP 1 Score: 170.244 bits (430), Expect = 2.188e-48
Identity = 126/353 (35.69%), Postives = 180/353 (50.99%), Query Frame = 3 
Query:  117 VRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVE---DVPIKFYKEPLSKADIVMEGKDVTMIGWGTQV-HVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            +R  SG   +     AP+      ++ + EA+N  +D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP+SE G  G  +G A AG   I E    ++   A DQ++N AAK  Y S        +  R P GA       HSQ   A+Y H PG+KVV P     AKGL+ S + DNNP +  E +++Y  A E   +   K +  P+ KA I  +G  +T++     V H L+  A LS  K  + CEVI+L+T+ P D + +  SV KT  LV         G GAEI A + E   FN L+AP  RVTG D P PY  + E   +P +   + AVK  +
Sbjct:   12 LRQASGLLKRRFHRSAPA----AVQLTVREAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSAG-LQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVMLENELMYGVAFELPAEAQSKDFLIPIGKAKIERQGTHITVVAHSRPVGHCLEAAAVLS--KEGIECEVINLRTIRPMDIEAIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKVLEDNSVPQVKDIIFAVKKTL 357
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. UniProt/SwissProt
Match: sp|P21839|ODBB_BOVIN (2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Bos taurus OX=9913 GN=BCKDHB PE=1 SV=2)

HSP 1 Score: 452.21 bits (1162), Expect = 7.647e-157
Identity = 228/340 (67.06%), Postives = 279/340 (82.06%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +  P E G+  KMNL +AV ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR+P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ Y  PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D V +SV KTGRL++SHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   53 HFTFQPDPEPVEYGQTQKMNLFQAVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVAAMAQEKLGVSCEVIDLRTILPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. UniProt/SwissProt
Match: sp|P21953|ODBB_HUMAN (2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHB PE=1 SV=2)

HSP 1 Score: 451.44 bits (1160), Expect = 2.019e-156
Identity = 227/340 (66.76%), Postives = 279/340 (82.06%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +  P E G+  KMNL ++V ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR+P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR A E+VPI+ Y  PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D + +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   53 HFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. UniProt/SwissProt
Match: sp|P35738|ODBB_RAT (2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Rattus norvegicus OX=10116 GN=Bckdhb PE=1 SV=3)

HSP 1 Score: 449.514 bits (1155), Expect = 9.677e-156
Identity = 226/340 (66.47%), Postives = 278/340 (81.76%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +    + G+  KMNL +++ ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ YK PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D V +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   51 HFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 390
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. UniProt/SwissProt
Match: sp|Q6P3A8|ODBB_MOUSE (2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Bckdhb PE=1 SV=2)

HSP 1 Score: 447.973 bits (1151), Expect = 4.085e-155
Identity = 226/340 (66.47%), Postives = 278/340 (81.76%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +    + G+  KMNL +++ ++LD  L KD +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG+A  GA AIAEIQFADYI PAFDQIVNEAAK RYRSG+ FNCG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PR P +AKGLLLSC+ED NPCIFFEPKILYR AVE VP++ YK PLS+A+++ EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDL+T+ PWD D V +SV KTGRL+ISHEAPLT GF +EI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C +A++ +I Y
Sbjct:   51 HFTFHPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 390
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. UniProt/SwissProt
Match: sp|Q55FN7|ODBB_DICDI (2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Dictyostelium discoideum OX=44689 GN=bkdB PE=3 SV=1)

HSP 1 Score: 412.149 bits (1058), Expect = 2.538e-141
Identity = 221/369 (59.89%), Postives = 274/369 (74.25%), Query Frame = 3 
Query:   57 RNKMIRKVISRLVKPNFRIWVRSYSGPH--FKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            R   I+KV S LV+           GP     Y S +     GE  KMNL +A+NN +D+ ++KDS A+VFGEDV FGGVFRCT GL+DKYG  R+FNTPL EQGI GF IG+AA GA  IAEIQFADYI PAFDQIVNEAAK RYRSG QF+CG LTIR+P GAVGHGG YHSQS E+++ H PG+KVV+P  PI+AKGLLL+ + + +P IFFEPK++YR AVE+VPI  Y+ PL KA IV EGKD+T+IGWG Q+ VL +   ++  K  +SCE+IDL+T+ PWD + V ESVKKTGR+VISHEAP T G+ AEI+A++QE CF +LEAPIQRV G+DTPFP I+E FY+PD  +  E++K  + Y
Sbjct:    3 RGNNIKKVNSLLVRSFHSTVGNRSGGPSTPINYPSLEI-ENAGEKQKMNLFQAINNGMDIAMQKDSKAVVFGEDVGFGGVFRCTVGLRDKYGASRVFNTPLCEQGIAGFAIGLAAQGATPIAEIQFADYIFPAFDQIVNEAAKYRYRSGGQFDCGSLTIRSPYGAVGHGGHYHSQSPESYFGHTPGLKVVIPSTPIEAKGLLLASIREKDPVIFFEPKLMYRSAVEEVPIGDYEIPLGKARIVKEGKDITIIGWGAQMRVLLQAVNMAEEKLGISCELIDLRTIQPWDVETVVESVKKTGRVVISHEAPKTGGWAAEISATIQERCFLHLEAPIQRVCGYDTPFPLIFEKFYVPDHLKNFESIKKTMVY 370
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. TrEMBL
Match: T1KER6 (Transket_pyr domain-containing protein OS=Tetranychus urticae OX=32264 GN=107363634 PE=4 SV=1)

HSP 1 Score: 485.337 bits (1248), Expect = 9.417e-168
Identity = 246/365 (67.40%), Postives = 302/365 (82.74%), Query Frame = 3 
Query:   63 KMIRKVISRLVKPNFRIWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            +M +K+ SRL+  N           HF Y  +   +  GE  +MNL +A+NNSLDL L  +SSA++FGEDV+FGGVFRCT GL+DK+GK+R+FNTPL EQGIVGFGIG+AAAGA AIAEIQFADYI PAFDQI+NEA+K RYR+GNQF+CG LTIR PCGAVGHG +YHSQSVE+F+ H+PG+K+V+PRGPI+AKGLL+SC+ED NPCIFFEPKILYR AVE VPIK YK PLSKA++V+EG DVT+IGWGTQVHVL EV +++    ++SCE+IDLQT+ PWD + V  SVKKTGR++I+HEAPLT GFGAEIAA++Q+ CF +LEAPI RVTGFDTPFP+IYEPFY+PD WRCL A+K +I +
Sbjct:   11 QMSQKMGSRLIVRN---------SAHFNYYPDTVAASEGETNRMNLFQAINNSLDLALTNNSSALIFGEDVAFGGVFRCTIGLQDKHGKERVFNTPLCEQGIVGFGIGLAAAGATAIAEIQFADYIFPAFDQILNEASKFRYRAGNQFDCGALTIRAPCGAVGHGALYHSQSVESFFAHIPGIKIVIPRGPIQAKGLLMSCIEDKNPCIFFEPKILYRAAVEQVPIKEYKIPLSKAEVVVEGDDVTLIGWGTQVHVLHEVCQMAQDSLNISCELIDLQTIVPWDRETVRNSVKKTGRVLIAHEAPLTGGFGAEIAATIQQECFLHLEAPISRVTGFDTPFPHIYEPFYIPDKWRCLHALKKLINF 366
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. TrEMBL
Match: A0A1D2N0C2 (2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Orchesella cincta OX=48709 GN=Ocin01_07955 PE=4 SV=1)

HSP 1 Score: 483.411 bits (1243), Expect = 2.476e-166
Identity = 237/348 (68.10%), Postives = 287/348 (82.47%), Query Frame = 3 
Query:  114 WVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            W RSYS  HF YV +  PS  GE  +MNL +AVNN++D+ L  D +AI+FGEDV+FGGVFRCT  L+DK+GKDR+FNTPL EQGI GFGIG A AGA  IAE+QFADYI PAFDQIVNEAAK RYR GNQF+CG LT R PCGAVGHG +YHSQS EA++ H PG+K+VMPRG +KAKGLLLSC+  N+PCIFFEPKILYR AVE VP + Y+ P+ KADI++EG++VT++GWGTQVHVL+EVA+L+  + +V+CEVIDL T+ PWD + ++ SV KTGRLVI+HEAPL  G GAEIAASVQ+ CF NLEAPIQRVTG DTPFP+++EPFY+PD WRCLEAV+  +E+
Sbjct:   59 WTRSYSA-HFTYVPDTVPSSEGETVRMNLFQAVNNAMDIALASDPTAIIFGEDVAFGGVFRCTLNLQDKHGKDRVFNTPLCEQGIAGFGIGAAVAGATVIAEMQFADYIFPAFDQIVNEAAKFRYRCGNQFDCGKLTFRAPCGAVGHGALYHSQSPEAYFAHTPGLKIVMPRGAVKAKGLLLSCIRSNDPCIFFEPKILYRSAVEQVPTRDYELPIGKADILLEGENVTLLGWGTQVHVLREVAQLAQDRLNVTCEVIDLVTIQPWDRETIFNSVTKTGRLVIAHEAPLNCGLGAEIAASVQKECFLNLEAPIQRVTGHDTPFPHVFEPFYIPDKWRCLEAVRVAVEF 405
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. TrEMBL
Match: A0A4Y2RGK3 (2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Araneus ventricosus OX=182803 GN=Bckdhb_3 PE=4 SV=1)

HSP 1 Score: 476.478 bits (1225), Expect = 4.413e-164
Identity = 241/345 (69.86%), Postives = 288/345 (83.48%), Query Frame = 3 
Query:  123 SYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            SY   HF YV +   +  GE  +MNL +AV N+LDL L  D SA++FGEDVSFGGVFRCT GL+DKYG+DR+FN+PL EQGIVGFGIG+A AGA  IAEIQFADYI PAFDQIVNEA+KLR+RSGN+FNCGGLTIR P GAVGHG +YHSQS EAF+ HVPG+KVV+PRGP++AKGLLLSC+ D NPCIFFEPKILYR AVE VP+K Y+ PLSKA+I+ EG DVT+IGWGTQVHVL+EV +L+  K ++SCE+IDL T+ PWD++ V  SVKKTGRL+++HEAPLT GFGAEIAA+VQ  CF NLEAPIQRVTG D PFP+IYEPF++P  WRC +A+K +I +
Sbjct:   33 SYRLSHFTYVPDTVSASDGETARMNLFQAVTNALDLALGTDPSAVIFGEDVSFGGVFRCTVGLQDKYGRDRVFNSPLCEQGIVGFGIGMAIAGATPIAEIQFADYIFPAFDQIVNEASKLRFRSGNEFNCGGLTIRAPYGAVGHGALYHSQSPEAFFAHVPGIKVVIPRGPLQAKGLLLSCIRDKNPCIFFEPKILYRMAVEQVPLKDYELPLSKAEILTEGDDVTVIGWGTQVHVLREVCQLAQDKLNISCELIDLVTILPWDKETVINSVKKTGRLLVAHEAPLTGGFGAEIAATVQNECFLNLEAPIQRVTGHDAPFPHIYEPFFIPSKWRCFDAIKKLINF 377
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. TrEMBL
Match: T1G9N6 (Transket_pyr domain-containing protein OS=Helobdella robusta OX=6412 GN=20217782 PE=4 SV=1)

HSP 1 Score: 476.863 bits (1226), Expect = 4.874e-164
Identity = 235/348 (67.53%), Postives = 286/348 (82.18%), Query Frame = 3 
Query:  114 WVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            + R YS   F YVS K P   GE  +MNLC+A+ +++D+ L +D + +VFGEDV+FGGVFRCT GLKDKYG DR+FNTPL EQGI GF IG A AGA  IAE+QFADYI PAFDQIVNEAAK RYRSG QF+CG LTIR+PCGAVGHG VYHSQS EAF+ HVPG+K+V+PRGPI+AKGLLLSC+ED+NPCIFFEPKILYR A+E+VPI  +  PLS+A++++EG DVT++GWGTQVHVL+EVAK++     VSCEVIDL+T+ PWD + V +SV KTGRL+ISHEAP+T GF +EIA+ +QE CF NLE PIQRV G+DTPFP+++EPFYLPD W+C EAVK  + Y
Sbjct:   40 YTRRYS-TSFSYVSSKVPDNAGEIKRMNLCQALTSAMDVALTEDPTTLVFGEDVAFGGVFRCTVGLKDKYGSDRVFNTPLCEQGIAGFAIGAACAGARVIAEMQFADYIFPAFDQIVNEAAKYRYRSGGQFDCGRLTIRSPCGAVGHGAVYHSQSPEAFFAHVPGLKIVIPRGPIQAKGLLLSCIEDDNPCIFFEPKILYRSAIEEVPIGRFLLPLSQAEVLIEGNDVTLVGWGTQVHVLQEVAKMAEEHLKVSCEVIDLRTILPWDSETVAKSVSKTGRLIISHEAPVTLGFASEIASKIQEECFLNLECPIQRVCGYDTPFPHVFEPFYLPDKWKCFEAVKKAVNY 386
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. TrEMBL
Match: A0A443QQ15 (2-oxoisovalerate dehydrogenase subunit beta-like protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_12240 PE=4 SV=1)

HSP 1 Score: 475.707 bits (1223), Expect = 7.180e-164
Identity = 235/360 (65.28%), Postives = 291/360 (80.83%), Query Frame = 3 
Query:   78 VISRLVKPNFRIWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            + S L+K    +  +     HF +      +  GE  ++NL +AVNN+LD+ L  D S  +FGEDV+FGGVFRCT GL+DKYGKDR+FNTPLSEQGIVGFGIG+A  GA +IAEIQFADYI PAFDQIVNEA+K RYRSGN F+CG LTIR PCGAVGHG +YHSQSVE+F+ H+PG+KVVMPRGPI+AKGLLLSC+ D NPCIFFEPKILYR AVE VP+K Y  PLSKAD+V+EG  +TM+GWGTQVH+L+EV +++    ++SCEVIDLQT+ PWD++ V  SVKKTGRL+I+HEAP+T+GFGAEIAA++Q  CF +LEAP+ RV G+DTPFP++YEPFY+PD W+C +AVK +I Y
Sbjct:    8 IFSFLLKKRLNVAFKRRYSTHFNFYPSTVAASEGETNRLNLFQAVNNALDIALASDPSTCIFGEDVAFGGVFRCTIGLQDKYGKDRVFNTPLSEQGIVGFGIGLAVVGATSIAEIQFADYIFPAFDQIVNEASKFRYRSGNHFDCGSLTIRAPCGAVGHGALYHSQSVESFFAHIPGIKVVMPRGPIQAKGLLLSCIRDKNPCIFFEPKILYRVAVEHVPVKDYVLPLSKADVVIEGDHLTMVGWGTQVHILQEVCQMAQDMLNISCEVIDLQTIIPWDKETVINSVKKTGRLLIAHEAPITAGFGAEIAATIQNECFLHLEAPVFRVAGYDTPFPHVYEPFYIPDKWKCFDAVKKLINY 367
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Cavefish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 451.055 bits (1159), Expect = 3.142e-157
Identity = 229/340 (67.35%), Postives = 278/340 (81.76%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF +  +  P++ G   KMNL +++ ++LD  L  D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIGVA AGA AIAEIQFADYI PAFDQIVNEAAK RYRSGN ++CG LTIR P G VGHG +YHSQS EA++ H PG+KVV+PRGP++AKGLLLSC+ D NPCIFFEPKILYR AVE VP + Y  PLS+A++V EG DVT++ WGTQVHV++EVA ++  K  VSCEVIDLQT+ PWD + V +SV KTGRL+ISHEAP+T GF AEI++S+QE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C EAVK +I Y
Sbjct:   58 HFAFHPDPVPTKYGPTVKMNLFQSITSALDNTLASDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGVAVAGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGNLYDCGNLTIRAPWGCVGHGSLYHSQSPEAYFAHCPGLKVVVPRGPVQAKGLLLSCIADENPCIFFEPKILYRAAVEQVPTEPYHLPLSQAEVVQEGSDVTLVAWGTQVHVMREVATMAQEKLGVSCEVIDLQTILPWDIETVCKSVVKTGRLLISHEAPVTGGFAAEISSSIQEQCFLNLEAPIARVCGYDTPFPHIFEPFYIPDKWKCFEAVKRMINY 397
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Cavefish
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:ZFIN;Acc:ZDB-GENE-040426-2173])

HSP 1 Score: 149.828 bits (377), Expect = 5.864e-41
Identity = 113/329 (34.35%), Postives = 168/329 (51.06%), Query Frame = 3 
Query:  189 KMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAV---EDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQV-HVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            ++ + +A+N ++D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP++E G  G  +G A AG   I E    ++   A DQ++N AAK  Y S        +  R P G              A+Y H PG+KVV P     AKGLL + + D+NP +F E +++Y  A    E+   K +  P+ KA +  +G  +T++     V H L   A L+  K  + CEVI+L+T+ P D + +  SV KT  L+         G GAEI A + E   FN L+AP  RVTG D P PY  I E    P I   + +VK  +
Sbjct:   32 QVTVRDALNQAMDEELERDERVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPITEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSAG-LQPVPIVFRGPNGCFA-----------AWYGHCPGLKVVSPWNSEDAKGLLKAAIRDDNPVVFLENELMYGVACEMSEEAQSKDFIIPIGKAKVERQGGHITLVSHSRMVGHCLDAAAVLA--KEGIECEVINLRTIRPLDVETIEASVMKTNHLITVEGGWPQFGVGAEICARIMEGPAFNYLDAPATRVTGVDIPMPYAKILEDNSTPQIKDIIFSVKKTL 346
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Yeast
Match: PDB1 (E1 beta subunit of the pyruvate dehydrogenase (PDH) complex; PDH is an evolutionarily conserved multi-protein complex found in mitochondria [Source:SGD;Acc:S000000425])

HSP 1 Score: 182.956 bits (463), Expect = 4.103e-54
Identity = 119/331 (35.95%), Postives = 182/331 (54.98%), Query Frame = 3 
Query:  192 MNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLS-------KADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPYI--YEPFYLPDIWRCLEAVKTVI 1151
            M + EA+N+++   L++D    + GE+V+ + G ++ +KGL D++G+ R+ +TP++E G  G  +G A  G   I E    ++   A D +VN AAK  Y SG    C  +  R P GA    G  HSQ    +Y  +PG+KV++P     A+GLL + + D NP +F E ++LY  + E       +E LS       KA I  EG D++++ +   V    E A++   K+ VS EVI+L+++ P D + + ++VKKT  L+       + G GAEI A V E+  F+ L+APIQRVTG D P PY    E F  PD    ++AVK V+
Sbjct:   39 MTVREALNSAMAEELDRDDDVFLIGEEVAQYNGAYKVSKGLLDRFGERRVVDTPITEYGFTGLAVGAALKGLKPIVEFMSFNFSMQAIDHVVNSAAKTHYMSGGTQKCQ-MVFRGPNGAAVGVGAQHSQDFSPWYGSIPGLKVLVPYSAEDARGLLKAAIRDPNPVVFLENELLYGESFE-----ISEEALSPEFTLPYKAKIEREGTDISIVTYTRNVQFSLEAAEILQKKYGVSAEVINLRSIRPLDTEAIIKTVKKTNHLITVESTFPSFGVGAEIVAQVMESEAFDYLDAPIQRVTGADVPTPYAKELEDFAFPDTPTIVKAVKEVL 363
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Nematostella
Match: EDO29237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T476])

HSP 1 Score: 387.497 bits (994), Expect = 4.840e-134
Identity = 206/322 (63.98%), Postives = 256/322 (79.50%), Query Frame = 3 
Query:  192 MNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            MN  +A+ +++D+ L+ D + ++FGEDV+FGGVFRCT GL++KYGKDR+FNTPLSEQGIVGFGIGVAAAG+ AIAEIQFADYI PAFDQ+VNEAAK RYRSGN F+CGGLT+R PCGAVGHG  YHSQSVE+F+ HVPGVKVV+PR PI+AKGLLL+ + D NP +FFEPKILYR AVEDVP+K Y  PLS+A+++ +G D++++G                        +IDL+T+ PWD+D V +SV+KTGRL+I+HEA  T GFG EIA++VQ+ CF +LEAPIQRV G+DTPFP+I EPFYLPD WRC EAVK VI +
Sbjct:    1 MNFFQALTDAMDIALDTDPTTVIFGEDVAFGGVFRCTVGLREKYGKDRVFNTPLSEQGIVGFGIGVAAAGSTAIAEIQFADYIFPAFDQLVNEAAKFRYRSGNLFDCGGLTVRAPCGAVGHGAHYHSQSVESFFAHVPGVKVVIPRSPIQAKGLLLASVRDPNPVVFFEPKILYRQAVEDVPVKDYSLPLSEAEVLEKGFDLSLVG-----------------------RLIDLRTILPWDKDTVCQSVEKTGRLLIAHEACHTGGFGGEIASTVQDRCFLSLEAPIQRVCGWDTPFPHILEPFYLPDKWRCFEAVKKVISF 299
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Nematostella
Match: EDO40608 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6S9])

HSP 1 Score: 154.451 bits (389), Expect = 7.269e-43
Identity = 110/327 (33.64%), Postives = 171/327 (52.29%), Query Frame = 3 
Query:  192 MNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVE---DVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            + + EA+N +++  +++D    + GE+V+ + G ++ +KGL   +G++RI +TP++E G  G  +G A AG   I E    ++   A DQ++N AAK  Y S        +  R P GA       HSQ   A+Y H PG+KVV P     AKGLL S + + NP +  E +++Y  + E   +     +  P+ KA I   G  +T++     V    + AK  L    +  EV++L+++ P D   + +SVKKT  LV         G GAEIAA+V E+  F+ L+API RVTG D P PY  + E   LP +   + +VK  +
Sbjct:   37 LTVREALNAAMEEEMKRDDRVFLLGEEVALYDGAYKVSKGLYKIFGEERIRDTPITEMGFAGIAVGAAMAGMRPICEFMTFNFAMQAIDQVINSAAKTFYMSAGDVPVP-IVFRGPNGAAAGVAAQHSQCYAAWYGHCPGLKVVSPYSAEDAKGLLKSAIREPNPVVVLENELMYGTSFEMSDEAMSADFLVPIGKAKIERPGSHITLVAHSRPVETCLQAAK-QLESEGIDVEVLNLRSIRPMDTQAIVDSVKKTNHLVTVEGGWPHFGVGAEIAATVMESEAFDFLDAPIIRVTGADIPMPYAALLEKNALPQVENIVNSVKKTL 361
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Medaka
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:NCBI gene;Acc:101170333])

HSP 1 Score: 454.136 bits (1167), Expect = 1.401e-158
Identity = 228/340 (67.06%), Postives = 279/340 (82.06%), Query Frame = 3 
Query:  138 HFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            HF Y  +  P++ GE  KMNL +++ ++LD  L  D +A++FGEDV+FGGVFRCT GL+DKYGKDR+FNTPL EQGIVGFGIG A AGA AIAEIQFADYI PAFDQIVNEAAK RYRSGN F+CG LTIR P G VGHG +YHSQS EAF+ H PG+KVV+PRGP++AKGLLLSC+ D NPCIFFEPKILYR AVE VP++ Y  PLS+A+I+ EG DVT++ WGTQ+HVL+EV+ ++  K  VSCEVIDL+T+ PWD + V +SV KTGRL++SHEAP+T GF AEI+++VQE CF NLEAPI RV G+DTPFP+I+EPFY+PD W+C EA+K +I Y
Sbjct:   50 HFTYQPDPVPTQYGETQKMNLFQSITSALDNTLSSDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGAAVAGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGNLFDCGNLTIRAPWGCVGHGSLYHSQSPEAFFAHCPGIKVVIPRGPMQAKGLLLSCITDQNPCIFFEPKILYRAAVEQVPVESYTIPLSEAEILQEGSDVTLVAWGTQIHVLREVSDMAQEKLGVSCEVIDLKTILPWDVETVCKSVVKTGRLLVSHEAPVTGGFAAEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCFEAIKRMINY 389
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Medaka
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:NCBI gene;Acc:100049362])

HSP 1 Score: 169.088 bits (427), Expect = 5.940e-48
Identity = 119/331 (35.95%), Postives = 174/331 (52.57%), Query Frame = 3 
Query:  183 CTKMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGA---VEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQV-HVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
              ++ + +A+N ++D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP+SE G  G  +G A AG   I E    ++   A DQ++N AAK  Y S  Q     +  R P GA       HSQ   A+Y H PG+KVV P     A+GLL S + D+NP +F E +++Y  +    E+   K +  P+ +A +  +G  VT++     V H L   A L+  K  + CEVI+L+T+ P D + +  SV KT  LV         G GAEI A V E   FN L+AP+ RVTG D P PY    E   LP +   + +VK  +
Sbjct:   31 AVQVTVRDALNQAMDEELERDERVFLMGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSAGQQPVP-IVFRGPNGASAGVAAQHSQCFAAWYAHCPGLKVVSPWNSEDARGLLKSAIRDDNPVVFLENELMYGVSFEMTEESQSKDFTIPIGEAKVERQGSHVTLVSHSRYVGHCLDAAAVLA--KEGIECEVINLRTIRPMDVESIEASVMKTNHLVTVEGGWPQFGVGAEICARVMEGPAFNYLDAPVTRVTGVDIPMPYAKTLEEHSLPQVKDIIFSVKKTL 358
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Medaka
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:NCBI gene;Acc:100049362])

HSP 1 Score: 168.318 bits (425), Expect = 1.449e-47
Identity = 119/324 (36.73%), Postives = 171/324 (52.78%), Query Frame = 3 
Query:  204 EAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGA---VEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQV-HVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
            +A+N ++D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP+SE G  G  +G A AG   I E    ++   A DQ++N AAK  Y S  Q     +  R P GA       HSQ   A+Y H PG+KVV P     A+GLL S + D+NP +F E +++Y  +    E+   K +  P+ +A +  +G  VT++     V H L   A L+  K  + CEVI+L+T+ P D + +  SV KT  LV         G GAEI A V E   FN L+AP+ RVTG D P PY    E   LP +   + +VK  +
Sbjct:   47 DALNQAMDEELERDERVFLMGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSAGQQPVP-IVFRGPNGASAGVAAQHSQCFAAWYAHCPGLKVVSPWNSEDARGLLKSAIRDDNPVVFLENELMYGVSFEMTEESQSKDFTIPIGEAKVERQGSHVTLVSHSRYVGHCLDAAAVLA--KEGIECEVINLRTIRPMDVESIEASVMKTNHLVTVEGGWPQFGVGAEICARVMEGPAFNYLDAPVTRVTGVDIPMPYAKTLEEHSLPQVKDIIFSVKKTL 367
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Medaka
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:NCBI gene;Acc:100049362])

HSP 1 Score: 164.081 bits (414), Expect = 1.490e-46
Identity = 112/331 (33.84%), Postives = 166/331 (50.15%), Query Frame = 3 
Query:  183 CTKMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGA---VEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQV-HVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPY--IYEPFYLPDIWRCLEAVKTVI 1151
              ++ + +A+N ++D  LE+D    + GE+V+ + G ++ ++GL  KYG  RI +TP+SE    G                   ++   A DQ++N AAK  Y S  Q     +  R P GA       HSQ   A+Y H PG+KVV P     A+GLL S + D+NP +F E +++Y  +    E+   K +  P+ +A +  +G  VT++     V H L   A L+  K  + CEVI+L+T+ P D + +  SV KT  LV         G GAEI A V E   FN L+AP+ RVTG D P PY    E   LP +   + +VK  +
Sbjct:   10 AVQVTVRDALNQAMDEELERDERVFLMGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEVTKPGVCFMTF-------------NFSMQAIDQVINSAAKTYYMSAGQQPVP-IVFRGPNGASAGVAAQHSQCFAAWYAHCPGLKVVSPWNSEDARGLLKSAIRDDNPVVFLENELMYGVSFEMTEESQSKDFTIPIGEAKVERQGSHVTLVSHSRYVGHCLDAAAVLA--KEGIECEVINLRTIRPMDVESIEASVMKTNHLVTVEGGWPQFGVGAEICARVMEGPAFNYLDAPVTRVTGVDIPMPYAKTLEEHSLPQVKDIIFSVKKTL 324
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Planmine SMEST
Match: SMESG000043691.1 (SMESG000043691.1)

HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0
Identity = 364/364 (100.00%), Postives = 364/364 (100.00%), Query Frame = 3 
Query:   66 MIRKVISRLVKPNFRIWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 1157
            MIRKVISRLVKPNFRIWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEQGIVGFGIGVAAAGAIAIAEIQFADYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY
Sbjct:    1 MIRKVISRLVKPNFRIWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVNNSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEQGIVGFGIGVAAAGAIAIAEIQFADYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPDIWRCLEAVKTVIEY 364
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Planmine SMEST
Match: SMESG000068622.1 (SMESG000068622.1)

HSP 1 Score: 164.081 bits (414), Expect = 2.941e-46
Identity = 116/329 (35.26%), Postives = 171/329 (51.98%), Query Frame = 3 
Query:  189 KMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVE---DVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPYI--YEPFYLPDIWRCLEAVKTVIE 1154
            K+ + +A+N +L   +E+D +  + GE+V+ + G ++ TKGL   +G +R+ +TP++E G  G  +G A  G   + E    ++   A D I+N AAK  Y S  Q     +  R P GA       HSQ   A+Y H P +KV+ P     AKGLL + + D +P IF E ++ Y  A E   +V    +  P+ KA I   G  V+++ +   V  L   A   L K  V CEV++L++L P DE+ V +SV KT  LV         G G+EI A V E+  FN L+AP  RVTG D P PY    E   LP +   +++VK V+ 
Sbjct:   29 KLTVRDALNQALKEEIERDKNVFILGEEVAQYDGAYKVTKGLWKLFGDERVVDTPITEMGFAGIAVGAAFHGLRPVCEFMTFNFAMQAVDHIINSAAKGYYMSAGQIKVP-IVFRGPNGAAAGVAAQHSQDFSAWYAHCPALKVLSPYSAEDAKGLLKTAIRDPDPVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVD-LCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESPAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLH 355
[Close]
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Planmine SMEST
Match: SMESG000068622.1 (SMESG000068622.1)

HSP 1 Score: 164.081 bits (414), Expect = 3.333e-46
Identity = 116/329 (35.26%), Postives = 171/329 (51.98%), Query Frame = 3 
Query:  189 KMNLCEAVNNSLDLILEKDSSAIVFGEDVS-FGGVFRCTKGLKDKYGKDRIFNTPLSEXXXXXXXXXXXXXXXXXXXXXXXXDYIHPAFDQIVNEAAKLRYRSGNQFNCGGLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSCLEDNNPCIFFEPKILYRGAVE---DVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPYI--YEPFYLPDIWRCLEAVKTVIE 1154
            K+ + +A+N +L   +E+D +  + GE+V+ + G ++ TKGL   +G +R+ +TP++E G  G  +G A  G   + E    ++   A D I+N AAK  Y S  Q     +  R P GA       HSQ   A+Y H P +KV+ P     AKGLL + + D +P IF E ++ Y  A E   +V    +  P+ KA I   G  V+++ +   V  L   A   L K  V CEV++L++L P DE+ V +SV KT  LV         G G+EI A V E+  FN L+AP  RVTG D P PY    E   LP +   +++VK V+ 
Sbjct:   33 KLTVRDALNQALKEEIERDKNVFILGEEVAQYDGAYKVTKGLWKLFGDERVVDTPITEMGFAGIAVGAAFHGLRPVCEFMTFNFAMQAVDHIINSAAKGYYMSAGQIKVP-IVFRGPNGAAAGVAAQHSQDFSAWYAHCPALKVLSPYSAEDAKGLLKTAIRDPDPVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVD-LCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESPAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLH 359
The following BLAST results are available for this feature:
BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BCKDHB4.205e-15766.76branched chain keto acid dehydrogenase E1 subunit ... [more]
BCKDHB4.205e-15766.76branched chain keto acid dehydrogenase E1 subunit ... [more]
BCKDHB2.389e-5868.75branched chain keto acid dehydrogenase E1 subunit ... [more]
PDHB5.319e-4835.75pyruvate dehydrogenase E1 beta subunit [Source:HGN... [more]
PDHB1.498e-4737.08pyruvate dehydrogenase E1 beta subunit [Source:HGN... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
bckd-1B3.030e-14761.31Branched Chain Keto acid Dehydrogenase e1 (E1) sub... [more]
pdhb-12.470e-4935.69Pyruvate dehydrogenase E1 component subunit beta, ... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG176912.592e-14960.22gene:FBgn0039993 transcript:FBtr0113761[more]
CG176912.592e-14960.22gene:FBgn0039993 transcript:FBtr0302409[more]
Pdhb2.062e-4834.15gene:FBgn0039635 transcript:FBtr0085369[more]
Pdhb2.062e-4834.15gene:FBgn0039635 transcript:FBtr0085366[more]
CG176912.496e-2449.45gene:FBgn0039993 transcript:FBtr0302410[more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bckdhb7.660e-15867.35branched chain keto acid dehydrogenase E1 subunit ... [more]
bckdhb7.660e-15867.35branched chain keto acid dehydrogenase E1 subunit ... [more]
bckdhb1.481e-15767.35branched chain keto acid dehydrogenase E1 subunit ... [more]
pdhb4.323e-4734.55pyruvate dehydrogenase E1 beta subunit [Source:ZFI... [more]
pdhb3.448e-2135.12pyruvate dehydrogenase E1 beta subunit [Source:ZFI... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cela2a1.191e-15467.78chymotrypsin like elastase 2A [Source:Xenbase;Acc:... [more]
cela2a5.189e-15468.52chymotrypsin like elastase 2A [Source:Xenbase;Acc:... [more]
cela2a1.219e-15367.89chymotrypsin like elastase 2A [Source:Xenbase;Acc:... [more]
cela2a1.484e-15365.88chymotrypsin like elastase 2A [Source:Xenbase;Acc:... [more]
cela2a1.344e-15268.11chymotrypsin like elastase 2A [Source:Xenbase;Acc:... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Bckdhb5.840e-15666.47branched chain ketoacid dehydrogenase E1, beta pol... [more]
Bckdhb8.847e-15468.94branched chain ketoacid dehydrogenase E1, beta pol... [more]
Bckdhb8.847e-15468.94branched chain ketoacid dehydrogenase E1, beta pol... [more]
Pdhb2.188e-4835.69pyruvate dehydrogenase (lipoamide) beta [Source:MG... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P21839|ODBB_BOVIN7.647e-15767.062-oxoisovalerate dehydrogenase subunit beta, mitoc... [more]
sp|P21953|ODBB_HUMAN2.019e-15666.762-oxoisovalerate dehydrogenase subunit beta, mitoc... [more]
sp|P35738|ODBB_RAT9.677e-15666.472-oxoisovalerate dehydrogenase subunit beta, mitoc... [more]
sp|Q6P3A8|ODBB_MOUSE4.085e-15566.472-oxoisovalerate dehydrogenase subunit beta, mitoc... [more]
sp|Q55FN7|ODBB_DICDI2.538e-14159.892-oxoisovalerate dehydrogenase subunit beta, mitoc... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1KER69.417e-16867.40Transket_pyr domain-containing protein OS=Tetranyc... [more]
A0A1D2N0C22.476e-16668.102-oxoisovalerate dehydrogenase subunit beta, mitoc... [more]
A0A4Y2RGK34.413e-16469.862-oxoisovalerate dehydrogenase subunit beta, mitoc... [more]
T1G9N64.874e-16467.53Transket_pyr domain-containing protein OS=Helobdel... [more]
A0A443QQ157.180e-16465.282-oxoisovalerate dehydrogenase subunit beta-like p... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
bckdhb3.142e-15767.35branched chain keto acid dehydrogenase E1 subunit ... [more]
pdhb5.864e-4134.35pyruvate dehydrogenase E1 beta subunit [Source:ZFI... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PDB14.103e-5435.95E1 beta subunit of the pyruvate dehydrogenase (PDH... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO292374.840e-13463.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO406087.269e-4333.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
bckdhb1.401e-15867.06branched chain keto acid dehydrogenase E1 subunit ... [more]
pdhb5.940e-4835.95pyruvate dehydrogenase E1 beta subunit [Source:NCB... [more]
pdhb1.449e-4736.73pyruvate dehydrogenase E1 beta subunit [Source:NCB... [more]
pdhb1.490e-4633.84pyruvate dehydrogenase E1 beta subunit [Source:NCB... [more]
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BLAST of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000043691.10.000e+0100.00SMESG000043691.1[more]
SMESG000068622.12.941e-4635.26SMESG000068622.1[more]
SMESG000068622.13.333e-4635.26SMESG000068622.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029650 ID=SMED30029650|Name=2-oxoisovalerate dehydrogenase subunit beta, mitochondrial|organism=Schmidtea mediterranea sexual|type=transcript|length=1338bp
ATTTCTTGTTTTAAAATGCGCAATATTTAAATGTTGTGAATATATTTTTT
TGTCATAGAAATAAAATGATTAGAAAAGTTATATCTAGATTAGTTAAACC
AAATTTTCGAATTTGGGTACGAAGTTATTCGGGACCACATTTTAAATATG
TATCAGAAAAAGCTCCTAGCGAGTTAGGGGAGTGTACAAAAATGAATTTA
TGTGAAGCAGTTAATAATTCATTAGATTTAATTTTAGAAAAAGATTCATC
AGCAATTGTGTTCGGGGAAGATGTGTCGTTTGGAGGTGTTTTTCGATGCA
CTAAAGGTCTTAAAGATAAATATGGTAAAGACAGAATATTCAATACCCCT
TTATCTGAGCAAGGTATCGTTGGATTCGGTATTGGGGTGGCGGCAGCAGG
AGCTATAGCTATTGCTGAAATTCAATTTGCAGATTATATCCATCCTGCAT
TTGATCAAATTGTAAATGAAGCGGCCAAGTTACGATATAGATCTGGAAAT
CAATTTAATTGTGGAGGGCTTACGATTAGAACTCCCTGTGGTGCAGTGGG
CCATGGCGGTGTTTATCATTCACAGTCTGTTGAGGCATTTTATACTCACG
TTCCCGGTGTAAAGGTTGTAATGCCTCGTGGTCCAATAAAAGCGAAAGGT
TTATTGTTGAGTTGTCTTGAAGACAATAATCCTTGTATATTCTTTGAGCC
TAAAATTCTTTACCGAGGAGCTGTTGAAGATGTTCCTATTAAATTCTATA
AAGAGCCTTTGAGTAAAGCTGATATTGTGATGGAAGGAAAAGATGTTACC
ATGATCGGTTGGGGCACTCAAGTTCATGTGTTAAAAGAAGTCGCAAAACT
TTCTTTAACGAAATTTGATGTTTCATGTGAAGTGATTGATTTGCAAACTC
TTTCTCCATGGGACGAGGATTTGGTTTATGAGTCTGTGAAGAAAACTGGT
CGTCTTGTAATATCTCATGAAGCCCCATTAACATCCGGATTCGGGGCAGA
AATCGCAGCTTCTGTTCAAGAAGCTTGTTTTTTTAATCTCGAGGCCCCAA
TCCAACGAGTGACTGGATTCGACACTCCATTTCCGTACATATATGAACCT
TTTTATTTACCCGACATATGGAGATGTTTGGAAGCTGTCAAAACTGTAAT
TGAATATTAAAAATATGTTTTAAAGGAAATGGAATACTTTTATTGTTGTG
GATGTTAAGTATATTACCAATACATTTGGCTTCCTAATATTCTGTTTTCG
ATGTCTTTGTCTACATTATTTCTTAAATATAAATGCTAATCGTGACAAAA
ACAGATAATGACAAATTTCCCTAAAAATTATAACTCGG
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protein sequence of SMED30029650-orf-1

>SMED30029650-orf-1 ID=SMED30029650-orf-1|Name=SMED30029650-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=365bp
MIRKVISRLVKPNFRIWVRSYSGPHFKYVSEKAPSELGECTKMNLCEAVN
NSLDLILEKDSSAIVFGEDVSFGGVFRCTKGLKDKYGKDRIFNTPLSEQG
IVGFGIGVAAAGAIAIAEIQFADYIHPAFDQIVNEAAKLRYRSGNQFNCG
GLTIRTPCGAVGHGGVYHSQSVEAFYTHVPGVKVVMPRGPIKAKGLLLSC
LEDNNPCIFFEPKILYRGAVEDVPIKFYKEPLSKADIVMEGKDVTMIGWG
TQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVIS
HEAPLTSGFGAEIAASVQEACFFNLEAPIQRVTGFDTPFPYIYEPFYLPD
IWRCLEAVKTVIEY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR005475Transketolase-like_Pyr-bd
IPR009014Transketo_C/PFOR_II
IPR033248Transketolase_C
IPR029061THDP-binding
Vocabulary: biological process
TermDefinition
GO:0008152metabolic process
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR005475Transketolase-like, pyrimidine-binding domainSMARTSM00861Transket_pyr_3coord: 43..218
e-value: 9.7E-60
score: 214.5
IPR005475Transketolase-like, pyrimidine-binding domainPFAMPF02779Transket_pyrcoord: 42..217
e-value: 6.1E-43
score: 146.5
NoneNo IPR availableGENE3DG3DSA:3.40.50.970coord: 39..235
e-value: 2.8E-85
score: 286.3
NoneNo IPR availablePANTHERPTHR42980:SF12-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIALcoord: 30..363
NoneNo IPR availablePANTHERPTHR42980FAMILY NOT NAMEDcoord: 30..363
NoneNo IPR availableCDDcd07036TPP_PYR_E1-PDHc-beta_likecoord: 47..213
e-value: 2.95993E-77
score: 233.139
NoneNo IPR availableTMHMMTMhelixcoord: 100..122
IPR033248Transketolase, C-terminal domainPFAMPF02780Transketolase_Ccoord: 234..342
e-value: 1.3E-32
score: 112.3
IPR009014Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain IIGENE3DG3DSA:3.40.50.920coord: 236..360
e-value: 1.1E-49
score: 169.5
IPR009014Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain IISUPERFAMILYSSF52922TK C-terminal domain-likecoord: 228..364
IPR029061Thiamin diphosphate-binding foldSUPERFAMILYSSF52518Thiamin diphosphate-binding fold (THDP-binding)coord: 26..222