Cyclin-dependent kinase 1

Overview
NameCyclin-dependent kinase 1
Smed IDSMED30029621
Length (bp)1258
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cyclin-dependent kinase 1 (SMED30029621) t-SNE clustered cells

Violin plots show distribution of expression levels for Cyclin-dependent kinase 1 (SMED30029621) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029621

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30029621h1SMcG0015408 dd_Smed_v4_31502_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30029621h1SMcG0015408 dd_Smed_v4_31502_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30029621h1SMcG0015408 dd_Smed_v4_31502_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30029621h1SMcG0015408 Contig40264newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30029621h1SMcG0015408 Contig40264uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
reproductive organSMED30029621h1SMcG0015408 Contig40264newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30029621h1SMcG0015408 Contig40264uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
zeta neoblastSMED30029621h1SMcG0015408 dd_Smed_v4_31502_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK1 (cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722])

HSP 1 Score: 371.703 bits (953), Expect = 1.507e-127
Identity = 178/312 (57.05%), Postives = 230/312 (73.72%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            + D+ KIEKIGEGTYGVVYKG++K TG   A+KKIRLE++E+GVPSTAIREISLLKEL HPNIV+L+  +MQD +L+L+FE+L+MDL++YLD++     MD  ++K ++YQILQG++FCH RRV+HRDLKPQNLL+D  GT IKLADFGLAR FG+P++  THE                   VVTLWYR+PE+L+GS RYS  VD+WS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L SH K+ +  +GLDL+S+ML+Y+P  RI+ + AL H YF +L+
Sbjct:    1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGT-IKLADFGLARAFGIPIRVYTHE-------------------VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKN-LDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK1 (cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722])

HSP 1 Score: 369.392 bits (947), Expect = 9.205e-127
Identity = 176/312 (56.41%), Postives = 229/312 (73.40%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            + D+ KIEKIGEGTYGVVYKG++K TG   A+KKIRLE++E+GVPSTAIREISLLKEL HPNIV+L+  +MQD +L+L+FE+L+MDL++YLD++     MD  ++K ++YQILQG++FCH RRV+HRDLKPQNLL+D  GT IKLADFGLAR FG+P++  THE                    +TLWYR+PE+L+GS RYS  VD+WS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L SH K+ +  +GLDL+S+ML+Y+P  RI+ + AL H YF +L+
Sbjct:    1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGT-IKLADFGLARAFGIPIRVYTHE-------------------AITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKN-LDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK3 (cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:HGNC:1772])

HSP 1 Score: 341.273 bits (874), Expect = 1.757e-115
Identity = 170/306 (55.56%), Postives = 218/306 (71.24%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFAN 1077
            F K+EKIGEGTYGVVYK KN++TG   ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L   +  + KL+LVFE+L+ DL++Y+D+   S  P+ +IK +++Q+LQG+ FCH  RVIHRDLKPQNLL++  G I KLADFGLAR FGVP++  THEV                   VTLWYRAPEIL+GSK Y+ AVD+WS+ CIFAEM T K LF GDSEIDQ+F+IF +LGTP+E+ WPGV+ L  +    P WT   L     + + P+G DL+ ++L Y+P  RI ++ AL H YF++
Sbjct:    4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAI-KLADFGLARAFGVPLRTYTHEV-------------------VTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPN-LEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK3 (cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:HGNC:1772])

HSP 1 Score: 341.273 bits (874), Expect = 1.757e-115
Identity = 170/306 (55.56%), Postives = 218/306 (71.24%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFAN 1077
            F K+EKIGEGTYGVVYK KN++TG   ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L   +  + KL+LVFE+L+ DL++Y+D+   S  P+ +IK +++Q+LQG+ FCH  RVIHRDLKPQNLL++  G I KLADFGLAR FGVP++  THEV                   VTLWYRAPEIL+GSK Y+ AVD+WS+ CIFAEM T K LF GDSEIDQ+F+IF +LGTP+E+ WPGV+ L  +    P WT   L     + + P+G DL+ ++L Y+P  RI ++ AL H YF++
Sbjct:    4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAI-KLADFGLARAFGVPLRTYTHEV-------------------VTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPN-LEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK2 (cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771])

HSP 1 Score: 328.561 bits (841), Expect = 1.176e-110
Identity = 166/312 (53.21%), Postives = 214/312 (68.59%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNR 1086
            + +F K+EKIGEGTYGVVYK +NK TG+  ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L   +  + KL+LVFE+L+ DL++++D    +  P+ +IK +++Q+LQGL FCH  RV+HRDLKPQNLL++  G  IKLADFGLAR FGVPV+  THE                   VVTLWYRAPEIL+G K YS AVD+WS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  WPGV+ +  +    P W      S     +  DG  L+S+ML Y+P  RI+++ AL H +F ++ +
Sbjct:    1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHE-------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDF-SKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-1 (Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:P34556])

HSP 1 Score: 360.147 bits (923), Expect = 5.560e-123
Identity = 175/326 (53.68%), Postives = 231/326 (70.86%), Query Frame = 1 
Query:  148 FSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNL-QCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKD------FMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            ++++DF K+EKIGEGTYGVVYKGKN++T    A+KKIRLE++++GVPSTA+REISLLKEL HPN+V L+  +MQ+ +LFL+FE+L+ DL+RY+D L +    P+  +K + +QILQ + FCH RRVIHRDLKPQNLLVD  G  IKLADFGLAR  G+P++  THE                   VVTLWYRAPEILMG++RYS  VD+WS+ CIFAEMAT KPLF+GDSEID++F+IF +LGTPTE  W GV  L  + +  P W  + L   F D       +      L+  +L+Y+P  R+N++ AL+H YF N++ S+LPA
Sbjct:   17 YTLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGA-IKLADFGLARAIGIPIRVYTHE-------------------VVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFDNMDTSKLPA 322
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-1 (Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:P34556])

HSP 1 Score: 360.147 bits (923), Expect = 5.560e-123
Identity = 175/326 (53.68%), Postives = 231/326 (70.86%), Query Frame = 1 
Query:  148 FSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNL-QCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKD------FMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            ++++DF K+EKIGEGTYGVVYKGKN++T    A+KKIRLE++++GVPSTA+REISLLKEL HPN+V L+  +MQ+ +LFL+FE+L+ DL+RY+D L +    P+  +K + +QILQ + FCH RRVIHRDLKPQNLLVD  G  IKLADFGLAR  G+P++  THE                   VVTLWYRAPEILMG++RYS  VD+WS+ CIFAEMAT KPLF+GDSEID++F+IF +LGTPTE  W GV  L  + +  P W  + L   F D       +      L+  +L+Y+P  R+N++ AL+H YF N++ S+LPA
Sbjct:   17 YTLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGA-IKLADFGLARAIGIPIRVYTHE-------------------VVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFDNMDTSKLPA 322
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-2 (Cyclin-dependent kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:O61847])

HSP 1 Score: 278.87 bits (712), Expect = 5.506e-91
Identity = 137/306 (44.77%), Postives = 198/306 (64.71%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS---MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYF 1071
            F  + +IGEGTYGVV+K  + +     ALK IR + DE+G+PST +REIS +K+L H NIVTL   +  + KL++VFE+++ DL+  L+ L+ +   + P  +K F++Q+L  L +CHLRR++HRDLKPQN+LV  +G +IK+ADFGLAR F  P +  THEV                   VTLWYR PEIL+GS+RYS ++D+WS+ CIF+E+A+ KPLF G+ EI Q+FKIF ++GTP    WPGV     + ++ P W  +         ++ +GLD++ E+L Y P  R+ ++ AL H YF
Sbjct:   15 FCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDIIYANSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSG-VIKIADFGLARNFSFPSRNYTHEV-------------------VTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIKSWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDVLREILRYPPERRLTAKGALSHRYF 300
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-5 (Cyclin-dependent-like kinase 5 [Source:UniProtKB/Swiss-Prot;Acc:G5ECH7])

HSP 1 Score: 276.944 bits (707), Expect = 7.031e-91
Identity = 135/307 (43.97%), Postives = 202/307 (65.80%), Query Frame = 1 
Query:  160 DFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATT-KPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFAN 1077
            ++ K+EKIGEGTYG V+K +NK +G+  ALK++RL++D++GVPS+A+REI +L+EL H N+V L   +  + KL LVFEY + DL+++ D+L   MD    +  + Q+L+GL FCH   V+HRDLKPQNLL++  GT +KLADFGLAR FGVPV+  + E                   VVTLWYR P++L G+K Y+ ++D+WS  CIFAE++   +PLF G    DQ+ +IF  LG+P+E++WP ++ L  +    P++  +   S     ++  G DL+ ++L+ NP  RI++  AL H+YFA+
Sbjct:    3 NYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNGT-LKLADFGLARAFGVPVRCFSAE-------------------VVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPY-PIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFAD 288
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: pct-1 (Cyclin-dependent kinase 17 [Source:UniProtKB/Swiss-Prot;Acc:Q8I7M8])

HSP 1 Score: 231.491 bits (589), Expect = 5.293e-70
Identity = 124/310 (40.00%), Postives = 182/310 (58.71%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPL-WTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            +  + K++K+GEGTY  V++G++  T  F ALK+IRLE +E G P TAIRE+SLL+ L H N+VTL   +  D  L LVFEY++ DL++Y+D+   +M    I+ F+YQ+L+GL +CH RRV+HRDLKPQNLL+ A G  +KLADFGLAR   VP K  ++E                   VVTLWYR P++L+GS  YS  +D+W V CI  EM   + LF G +  +Q+  IF  LG+P  +  P +    ++       +    LC      +   G +L+ + L Y   DR+++ +A+ H +   +
Sbjct:  235 LETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEE-GAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGE-LKLADFGLARAKSVPTKTYSNE-------------------VVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPR-IDAHGFELLMKFLQYEGKDRVSAAEAVKHPFLRTI 522
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk1 (gene:FBgn0004106 transcript:FBtr0080051)

HSP 1 Score: 365.54 bits (937), Expect = 1.682e-125
Identity = 170/308 (55.19%), Postives = 234/308 (75.97%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYF 1071
            + DF KIEKIGEGTYGVVYKG+N+ TG   A+KKIRLE+D++GVPSTAIREISLLKEL H NIV L+  +M++ +++L+FE+L+MDL++Y+D+L     M+  +++ ++YQI   +LFCH RRV+HRDLKPQNLL+D +G +IK+ADFGL R+FG+PV+  THE+                   VTLWYRAPE+L+GS RYSC VD+WS+ CIFAEMAT KPLF+GDSEIDQ+F++F +L TPTE+ WPGV+ L  + +  P W+T++L +  K+ +  +G+DLI +ML+Y+P  RI+++D L H YF
Sbjct:    1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSG-LIKVADFGLGRSFGIPVRIYTHEI-------------------VTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKN-LDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0083922)

HSP 1 Score: 302.753 bits (774), Expect = 1.275e-100
Identity = 155/309 (50.16%), Postives = 206/309 (66.67%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            + +F + EKIGEGTYG+VYK ++  TG   ALKKIRLE + +GVPSTAIREISLLK L HPN+V L   ++    L+++FEYLNMDL++ +D  +    P +IK +++QIL  + FCH  R++HRDLKPQNLLVD  G  IKLADFGLAR F VP++A THE                   VVTLWYRAPEIL+G+K YS  VD+WS+ CIF+EM   + LF GDSEIDQ+++IF  L TP E +WPGV+ L  + +  P W  + +     +    +  +LI  ML Y+P  RI+++DAL H+YF N+
Sbjct:    5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-IKLADFGLARAFNVPMRAYTHE-------------------VVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEH---EAHELIMSMLCYDPNLRISAKDALQHAYFRNV 290
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0300447)

HSP 1 Score: 302.753 bits (774), Expect = 1.275e-100
Identity = 155/309 (50.16%), Postives = 206/309 (66.67%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            + +F + EKIGEGTYG+VYK ++  TG   ALKKIRLE + +GVPSTAIREISLLK L HPN+V L   ++    L+++FEYLNMDL++ +D  +    P +IK +++QIL  + FCH  R++HRDLKPQNLLVD  G  IKLADFGLAR F VP++A THE                   VVTLWYRAPEIL+G+K YS  VD+WS+ CIF+EM   + LF GDSEIDQ+++IF  L TP E +WPGV+ L  + +  P W  + +     +    +  +LI  ML Y+P  RI+++DAL H+YF N+
Sbjct:    5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-IKLADFGLARAFNVPMRAYTHE-------------------VVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEH---EAHELIMSMLCYDPNLRISAKDALQHAYFRNV 290
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0083921)

HSP 1 Score: 302.753 bits (774), Expect = 1.275e-100
Identity = 155/309 (50.16%), Postives = 206/309 (66.67%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            + +F + EKIGEGTYG+VYK ++  TG   ALKKIRLE + +GVPSTAIREISLLK L HPN+V L   ++    L+++FEYLNMDL++ +D  +    P +IK +++QIL  + FCH  R++HRDLKPQNLLVD  G  IKLADFGLAR F VP++A THE                   VVTLWYRAPEIL+G+K YS  VD+WS+ CIF+EM   + LF GDSEIDQ+++IF  L TP E +WPGV+ L  + +  P W  + +     +    +  +LI  ML Y+P  RI+++DAL H+YF N+
Sbjct:    5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-IKLADFGLARAFNVPMRAYTHE-------------------VVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEH---EAHELIMSMLCYDPNLRISAKDALQHAYFRNV 290
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk5 (gene:FBgn0013762 transcript:FBtr0087350)

HSP 1 Score: 285.804 bits (730), Expect = 2.467e-94
Identity = 145/313 (46.33%), Postives = 203/313 (64.86%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATT-KPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRS 1089
            +  + K+EKIGEGTYG V+KG+N+ T +  ALK++RL+ D++GVPS+A+REI LLKEL H NIV L   +  D KL LVFE+ + DL++Y D+L   +D  V + F+ Q+L+GL FCH   V+HRDLKPQNLL++  G  +KLADFGLAR FG+PVK  + E                   VVTLWYR P++L G+K Y+ ++D+WS  CI AE+A   +PLF G   +DQ+ KIF +LGTP E+ WPGVSHLS + + LP +      S     ++  G DL+ ++L+  P  RI++  A+ H YF + + S
Sbjct:    1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGE-LKLADFGLARAFGIPVKCYSAE-------------------VVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVA-LPSFPAITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSSSS 292
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1])

HSP 1 Score: 384.415 bits (986), Expect = 8.463e-133
Identity = 182/318 (57.23%), Postives = 237/318 (74.53%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG+NK TG   A+KKIRLE++E+GVPSTA+REISLLKEL HPN+V L   +MQ+ KL+LVFE+L+MDL++YLD++     MDPM++K ++YQIL+G+LFCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VD+WS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W +  L +  K+ +  +G+DL+ +ML+Y+PP RI++R A+ H YF +L++S LPA
Sbjct:    1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGEFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGASRYSTPVDLWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKSGNLANTVKN-LDKNGIDLLMKMLIYDPPKRISARQAMTHPYFDDLDKSSLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1])

HSP 1 Score: 384.415 bits (986), Expect = 8.463e-133
Identity = 182/318 (57.23%), Postives = 237/318 (74.53%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG+NK TG   A+KKIRLE++E+GVPSTA+REISLLKEL HPN+V L   +MQ+ KL+LVFE+L+MDL++YLD++     MDPM++K ++YQIL+G+LFCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VD+WS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W +  L +  K+ +  +G+DL+ +ML+Y+PP RI++R A+ H YF +L++S LPA
Sbjct:    1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGEFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGASRYSTPVDLWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKSGNLANTVKN-LDKNGIDLLMKMLIYDPPKRISARQAMTHPYFDDLDKSSLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 336.65 bits (862), Expect = 4.834e-114
Identity = 169/311 (54.34%), Postives = 218/311 (70.10%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            +  F K+EKIGEGTYGVVYK KNK TG+  ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L+  +  + KL+LVFE+L+ DL+R++D+   S   + ++K +++Q+LQGL FCH  RV+HRDLKPQNLL++A G  IKLADFGLAR FGVPV+  THE                   VVTLWYRAPEIL+G K YS AVD+WS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E+ WPGV+ +  +    P W    L S     +  DG DL+ +ML Y+P  RI++++AL+H +F ++ 
Sbjct:    1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLRDVIHTENKLYLVFEFLHQDLKRFMDSTSVSGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGE-IKLADFGLARAFGVPVRTYTHE-------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDESIWPGVTSMPDYKPSFPKWARQDL-SKVVPPLDEDGRDLLGQMLTYDPNKRISAKNALVHRFFRDVT 290
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk5 (cyclin-dependent kinase 5 [Source:ZFIN;Acc:ZDB-GENE-010131-2])

HSP 1 Score: 291.197 bits (744), Expect = 2.652e-96
Identity = 145/310 (46.77%), Postives = 203/310 (65.48%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATT-KPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            +  + K+EKIGEGTYG V+K KN++T +  ALK++RL++D++GVPS+A+REI LLKEL H NIV L   +  D KL LVFEY + DL++Y D+    +DP ++K F+YQ+L+GL FCH R V+HRDLKPQNLL++  G  +KLADFGLAR FG+PV+  + E                   VVTLWYR P++L G+K YS ++D+WS  CIFAE+A   +PLF G+   DQ+ +IF LLGTPTE  W  ++ L  +    P++  +    +    +S  G DL+  +L  NP  RI++ +AL H YFA+ 
Sbjct:    1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRNVLHRDLKPQNLLINRNGE-LKLADFGLARAFGIPVRCYSAE-------------------VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWQTMNKLPDYKPY-PMYPATTSLVNVVPKLSSTGRDLLQNLLKCNPVQRISAEEALQHPYFADF 289
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk17 (cyclin-dependent kinase 17 [Source:ZFIN;Acc:ZDB-GENE-041210-15])

HSP 1 Score: 275.404 bits (703), Expect = 4.328e-87
Identity = 141/310 (45.48%), Postives = 200/310 (64.52%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM-LPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            +  +IK++K+GEGTY  V+KG++K T +  ALK+IRLE++E G P TAIRE+SLLK+L H NIVTL   +  D  L LVFEYL+ DL++Y+D+    M    +K F++QIL+GL +CH R+V+HRDLKPQNLL++  G  +KLADFGLAR   VP K  ++E                   VVTLWYR P++L+GS  YS  +D+W V CIF EMA  +PLF G +  D++  IF LLGTPTE++WPG+S +  + S   P +      +H    +  +G++L+   L Y    RI++ +++ HSYF +L
Sbjct:  192 LETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEE-GAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKIFLFQILRGLAYCHRRKVLHRDLKPQNLLINERGE-LKLADFGLARAKSVPTKTYSNE-------------------VVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFYEMAAGRPLFPGSTVEDELHLIFRLLGTPTEDNWPGISSIEEFKSYNFPKYKPQPFINHAPR-LDTEGIELLLSFLRYESKKRISADESMKHSYFKSL 479
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cfap65 (cilia and flagella associated protein 65 [Source:Xenbase;Acc:XB-GENE-1001102])

HSP 1 Score: 384.8 bits (987), Expect = 1.105e-132
Identity = 185/319 (57.99%), Postives = 238/319 (74.61%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            + ++ KIEKIGEGTYGVVYKG++K TG   A+KKIRLEN+E+GVPSTAIREISLLKEL HPNIV L   +MQD +L+L+FE+L+MDL++YLD++     +D M++K ++YQILQG++FCH RRV+HRDLKPQNLL+D+ G +IKLADFGLAR FG+PV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L ++ K+ +  DGLDL+S+ML+Y+P  RI++R ALLH YF +L++S LPA+
Sbjct:    1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKG-VIKLADFGLARAFGIPVRVYTHE-------------------VVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKN-IDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPAN 298
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cfap65 (cilia and flagella associated protein 65 [Source:Xenbase;Acc:XB-GENE-1001102])

HSP 1 Score: 367.081 bits (941), Expect = 8.653e-126
Identity = 181/316 (57.28%), Postives = 232/316 (73.42%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            F+KI  I   TYGVVYKG++K TG   A+KKIRLEN+E+GVPSTAIREISLLKEL HPNIV L   +MQD +L+L+FE+L+MDL++YLD++     +D M++K ++YQILQG++FCH RRV+HRDLKPQNLL+D+ G +IKLADFGLAR FG+PV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L ++ K+ +  DGLDL+S+ML+Y+P  RI++R ALLH YF +L++S LPA+
Sbjct:    4 FLKIRIIC--TYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKG-VIKLADFGLARAFGIPVRVYTHE-------------------VVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKN-IDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPAN 296
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cfap65 (cilia and flagella associated protein 65 [Source:Xenbase;Acc:XB-GENE-1001102])

HSP 1 Score: 366.696 bits (940), Expect = 9.049e-126
Identity = 178/310 (57.42%), Postives = 228/310 (73.55%), Query Frame = 1 
Query:  181 IGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            I   TYGVVYKG++K TG   A+KKIRLEN+E+GVPSTAIREISLLKEL HPNIV L   +MQD +L+L+FE+L+MDL++YLD++     +D M++K ++YQILQG++FCH RRV+HRDLKPQNLL+D+ G +IKLADFGLAR FG+PV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L ++ K+ +  DGLDL+S+ML+Y+P  RI++R ALLH YF +L++S LPA+
Sbjct:    3 IYTSTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKG-VIKLADFGLARAFGIPVRVYTHE-------------------VVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKN-IDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPAN 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cdk2 (cyclin-dependent kinase 2 [Source:NCBI gene;Acc:493498])

HSP 1 Score: 333.569 bits (854), Expect = 1.271e-112
Identity = 167/315 (53.02%), Postives = 219/315 (69.52%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS-MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSP---DGLDLISEMLLYNPPDRINSRDALLHSYFANLNR 1086
            + +F K+EKIGEGTYGVVYK +N++TG+  ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L   +  + KL+LVFE+LN DL++++D    S +   ++K +++Q+LQGL FCH  RV+HRDLKPQNLL+++ G  IKLADFGLAR FGVPV+  THE                   VVTLWYRAPEIL+G K YS AVD+WS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  WPGV+ +  + S  P W        F   + P   DG DL+++ML Y+   RI+++ AL H++F +++R
Sbjct:    1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINSEGA-IKLADFGLARAFGVPVRTYTHE-------------------VVTLWYRAPEILLGCKFYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGVTTMPDYKSTFPKWVR----QDFSKVVPPLDDDGRDLLAQMLQYDSNKRISAKAALTHAFFRDVSR 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cfap65 (cilia and flagella associated protein 65 [Source:Xenbase;Acc:XB-GENE-1001102])

HSP 1 Score: 322.398 bits (825), Expect = 1.559e-108
Identity = 159/313 (50.80%), Postives = 213/313 (68.05%), Query Frame = 1 
Query:  172 IEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            +++    TYGVVYKG++K TG   A+KKIRLEN+E+GVP                    L+  +MQD +L+L+FE+L+MDL++YLD++     +D M++K ++YQILQG++FCH RRV+HRDLKPQNLL+D+ G +IKLADFGLAR FG+PV+  THEV                   VTLWYRAPE+L+GS RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L ++ K+ +  DGLDL+S+ML+Y+P  RI++R ALLH YF +L++S LPA+
Sbjct:    2 VQRFIRCTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPMIPC--------------FPLQNVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKG-VIKLADFGLARAFGIPVRVYTHEV-------------------VTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKN-IDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPAN 279
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk1 (cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:MGI:88351])

HSP 1 Score: 370.163 bits (949), Expect = 3.998e-127
Identity = 177/312 (56.73%), Postives = 231/312 (74.04%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            + D+IKIEKIGEGTYGVVYKG+++ TG   A+KKIRLE++E+GVPSTAIREISLLKEL HPNIV+L+  +MQD +L+L+FE+L+MDL++YLD++     MD  ++K +++QILQG++FCH RRV+HRDLKPQNLL+D  GT IKLADFGLAR FG+P++  THE                   VVTLWYR+PE+L+GS RYS  VD+WS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L SH K+ +  +GLDL+S+ML+Y+P  RI+ + AL H YF +L+
Sbjct:    1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKGT-IKLADFGLARAFGIPIRVYTHE-------------------VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKN-LDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLD 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk1 (cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:MGI:88351])

HSP 1 Score: 370.163 bits (949), Expect = 3.998e-127
Identity = 177/312 (56.73%), Postives = 231/312 (74.04%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            + D+IKIEKIGEGTYGVVYKG+++ TG   A+KKIRLE++E+GVPSTAIREISLLKEL HPNIV+L+  +MQD +L+L+FE+L+MDL++YLD++     MD  ++K +++QILQG++FCH RRV+HRDLKPQNLL+D  GT IKLADFGLAR FG+P++  THE                   VVTLWYR+PE+L+GS RYS  VD+WS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W    L SH K+ +  +GLDL+S+ML+Y+P  RI+ + AL H YF +L+
Sbjct:    1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKGT-IKLADFGLARAFGIPIRVYTHE-------------------VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKN-LDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLD 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk2 (cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:MGI:104772])

HSP 1 Score: 331.643 bits (849), Expect = 4.280e-112
Identity = 169/315 (53.65%), Postives = 217/315 (68.89%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSP---DGLDLISEMLLYNPPDRINSRDALLHSYFANLNR 1086
            + +F K+EKIGEGTYGVVYK KNK TG+  ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L   +  + KL+LVFE+L+ DL++++D    +  P+ +IK +++Q+LQGL FCH  RV+HRDLKPQNLL++A G+ IKLADFGLAR FGVPV+  THE                   VVTLWYRAPEIL+G K YS AVD+WS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  WPGV+ +  +    P W        F   + P   DG  L+S+ML Y+P  RI+++ AL H +F ++ +
Sbjct:    1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGS-IKLADFGLARAFGVPVRTYTHE-------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWAR----QDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk3 (cyclin-dependent kinase 3 [Source:MGI Symbol;Acc:MGI:1916931])

HSP 1 Score: 330.872 bits (847), Expect = 1.396e-111
Identity = 167/305 (54.75%), Postives = 212/305 (69.51%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFA 1074
            F K+EKIGEGTYGVVYK +NK TG   ALKKIRL+ + +GVPSTA+REISLLKEL HPNI+ L   + ++ KL++VFE+L  DL+R++D+   S  P+ V+K ++ Q+L+G+ FCH  RVIHRDLKPQNLL+D  G  IKLADFGLAR FGVP++  THE                   VVTLWYRAPEIL+GSK YS AVD+ S+ CIFAEM T K LF GDSEIDQ+F+IF  LGTP+E  WPGVS +  + S  P W+   L       + P+G DL+  +L Y+P  RI+++ AL H YF+
Sbjct:    4 FQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKHPNIIKLLDVVHREKKLYMVFEFLTQDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSFCHSHRVIHRDLKPQNLLLDGLGA-IKLADFGLARAFGVPLRTYTHE-------------------VVTLWYRAPEILLGSKFYSTAVDI*SIGCIFAEMVTGKALFPGDSEIDQLFRIFRTLGTPSEATWPGVSQMPDYQSSFPKWSRKGL-EEIVPSLGPEGKDLLLRLLQYDPSQRISAKTALAHPYFS 287
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk2 (cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:MGI:104772])

HSP 1 Score: 308.145 bits (788), Expect = 3.855e-102
Identity = 168/360 (46.67%), Postives = 216/360 (60.00%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEM------------------------------------------------ATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNR 1086
            + +F K+EKIGEGTYGVVYK KNK TG+  ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L   +  + KL+LVFE+L+ DL++++D    +  P+ +IK +++Q+LQGL FCH  RV+HRDLKPQNLL++A G+ IKLADFGLAR FGVPV+  THE                   VVTLWYRAPEIL+G K YS AVD+WS+ CIFAEM                                                 T + LF GDSEIDQ+F+IF  LGTP E  WPGV+ +  +    P W      S     +  DG  L+S+ML Y+P  RI+++ AL H +F ++ +
Sbjct:    1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGS-IKLADFGLARAFGVPVRTYTHE-------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMHLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSAPHPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDF-SKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 339
[Close]
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|P51958|CDK1_CARAU (Cyclin-dependent kinase 1 OS=Carassius auratus OX=7957 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 1.515e-133
Identity = 184/318 (57.86%), Postives = 238/318 (74.84%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG+NK TG   A+KKIRLE++E+GVPSTA+REISLLKEL HPN+V L   +MQ+ KL+LVFE+L+MDL++YLD++     MDPM++K ++YQIL+G+LFCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF  LGTP    WP V  L  + +  P W +  L S  K+ +  +G+DL+++ML+Y+PP RI++R A+ H YF +L++S LPA
Sbjct:    1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKSGNLASTVKN-LDKNGIDLLTKMLIYDPPKRISARQAMTHPYFDDLDKSTLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|Q9DGD3|CDK1_ORYLA (Cyclin-dependent kinase 1 OS=Oryzias latipes OX=8090 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 383.645 bits (984), Expect = 1.420e-131
Identity = 181/318 (56.92%), Postives = 237/318 (74.53%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG++K TG   A+KKIRLE++E+GVPSTA+RE+SLL+EL HPN+V L   +MQ+ +L+L+FE+L+MDL++YLD++     MDPM++K ++YQIL+G+ FCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS   IFAE+AT KPLF GDSEIDQ+F+IF  LGTP  + WP V  L  + +  P W    L S  K+ +  +GLDL+++ML+YNPP RI++R+A+ H YF +L++S LPA
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWKEGSLSSMVKN-LDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|Q9DG98|CDK1_ORYLU (Cyclin-dependent kinase 1 OS=Oryzias luzonensis OX=104659 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 383.259 bits (983), Expect = 1.927e-131
Identity = 181/318 (56.92%), Postives = 237/318 (74.53%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG++K TG   A+KKIRLE++E+GVPSTA+RE+SLL+EL HPN+V L   +MQ+ +L+L+FE+L+MDL++YLD++     MDPM++K ++YQIL+G+ FCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS   IFAE+AT KPLF GDSEIDQ+F+IF  LGTP  + WP V  L  + +  P W    L S  K+ +  +GLDL+++ML+YNPP RI++R+A+ H YF +L++S LPA
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWKGGSLSSMVKN-LDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|Q9DGA2|CDK1_ORYJA (Cyclin-dependent kinase 1 OS=Oryzias javanicus OX=123683 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 383.259 bits (983), Expect = 2.013e-131
Identity = 181/318 (56.92%), Postives = 237/318 (74.53%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG++K TG   A+KKIRLE++E+GVPSTA+RE+SLL+EL HPN+V L   +MQ+ +L+L+FE+L+MDL++YLD++     MDPM++K ++YQIL+G+ FCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS   IFAE+AT KPLF GDSEIDQ+F+IF  LGTP  + WP V  L  + +  P W    L S  K+ +  +GLDL+++ML+YNPP RI++R+A+ H YF +L++S LPA
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWMEGSLSSMVKN-LDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|Q9DGA5|CDK1_ORYCU (Cyclin-dependent kinase 1 OS=Oryzias curvinotus OX=104658 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 383.259 bits (983), Expect = 2.057e-131
Identity = 181/318 (56.92%), Postives = 237/318 (74.53%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG++K TG   A+KKIRLE++E+GVPSTA+RE+SLL+EL HPN+V L   +MQ+ +L+L+FE+L+MDL++YLD++     MDPM++K ++YQIL+G+ FCH RRV+HRDLKPQNLL+D  G +IKLADFGL+R FGVPV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS   IFAE+AT KPLF GDSEIDQ+F+IF  LGTP  + WP V  L  + S  P W    L S  K+ +  +GLDL+++ML+YNPP RI++R+A+ H YF +L++S LPA
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKG-VIKLADFGLSRAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKSTFPKWKGGSLSSMVKN-LDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A0X3PVC9 (Cyclin-dependent kinase 1 OS=Schistocephalus solidus OX=70667 GN=CDK1 PE=3 SV=1)

HSP 1 Score: 422.55 bits (1085), Expect = 8.469e-143
Identity = 206/333 (61.86%), Postives = 250/333 (75.08%), Query Frame = 1 
Query:  148 FSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDN--LQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWN-SMLPLWTTSRLCSHFK--DFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPF 1131
            +++SDF+++EKIGEGTYGVVYK +NKK    AALKKIRLEN+E+GVPSTAIREISLLKEL HPNIV L+Q +M+ G+L+LVFEYLN+DL+RYLD    Q  +DPM++K F+YQ+LQGLLFCH RRVIHRDLKPQN+LVD    I+KLADFGLAR FGVPV+ LTHE                   VVTLWYRAPEIL+G++RYSCAVDVWS+ CIFAE+AT + LFRGDSEIDQIF+IF  LGTP+E  W GV+ L  +     P W  S+L  + K    M   GL+L+  ML+Y P  RIN R+ALLHSYFA+L+RS +PA GEE+   P 
Sbjct:    7 YALSDFVRLEKIGEGTYGVVYKCRNKKNSKLAALKKIRLENEEEGVPSTAIREISLLKELSHPNIVNLQQVIMERGRLYLVFEYLNVDLKRYLDEHGRQNLLDPMLVKSFMYQMLQGLLFCHARRVIHRDLKPQNVLVDVPNKIVKLADFGLARAFGVPVRVLTHE-------------------VVTLWYRAPEILLGAQRYSCAVDVWSMGCIFAEVATKEALFRGDSEIDQIFRIFRALGTPSEEVWSGVTSLPEFQKKTFPTWQDSKLTENEKMQKTMGSTGLELLKAMLIYEPARRINVREALLHSYFADLDRSSVPAIGEEYVGLPL 320
[Close]
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A183LHM5 (Protein kinase domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS3300 PE=3 SV=1)

HSP 1 Score: 421.394 bits (1082), Expect = 2.844e-142
Identity = 208/344 (60.47%), Postives = 260/344 (75.58%), Query Frame = 1 
Query:  121 MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDN--LQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM-LPLWTTSRLCSH---FKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFE 1134
            M+T  N   +++SDFI++EKIGEGTYGVVYK KNK  G FAALKKIRLENDE+GVPSTAIREISLLKEL HPNIV L+Q +M++G+L+LVFEYLN+DL+RYLD+   +  ++P ++K F+YQ+LQGLLFCH RRVIHRDLKPQN+LVD    I+KLADFGLAR FG+PV+ LTHE                   VVTLWYRAPEIL+G++RYSCAVD+WS+ CIF+E++T + LFRGDSEIDQ+F+IF LLGTP+E  WPGVS L  +     P+W  S+L       K F SP GLDL+  ML+Y P  RI +RDALLH YF++L++S +PA GEE+   P +
Sbjct:    1 MSTRGN---YALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNVDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHE-------------------VVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPIWRNSKLSIQDNIAKAFTSP-GLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEEYIGLPLD 321
[Close]
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A183K468 (Protein kinase domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS9786 PE=3 SV=1)

HSP 1 Score: 421.394 bits (1082), Expect = 2.875e-142
Identity = 208/344 (60.47%), Postives = 260/344 (75.58%), Query Frame = 1 
Query:  121 MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDN--LQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM-LPLWTTSRLCSH---FKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFE 1134
            M+T  N   +++SDFI++EKIGEGTYGVVYK KNK  G FAALKKIRLENDE+GVPSTAIREISLLKEL HPNIV L+Q +M++G+L+LVFEYLN+DL+RYLD+   +  ++P ++K F+YQ+LQGLLFCH RRVIHRDLKPQN+LVD    I+KLADFGLAR FG+PV+ LTHE                   VVTLWYRAPEIL+G++RYSCAVD+WS+ CIF+E++T + LFRGDSEIDQ+F+IF LLGTP+E  WPGVS L  +     P+W  S+L       K F SP GLDL+  ML+Y P  RI +RDALLH YF++L++S +PA GEE+   P +
Sbjct:    1 MSTRGN---YALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNLDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHE-------------------VVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPIWRNSKLSIQDNIAKAFTSP-GLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEEYIGLPLD 321
[Close]
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A183NHN0 (Protein kinase domain-containing protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS1616 PE=3 SV=1)

HSP 1 Score: 421.394 bits (1082), Expect = 2.875e-142
Identity = 208/344 (60.47%), Postives = 260/344 (75.58%), Query Frame = 1 
Query:  121 MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDN--LQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM-LPLWTTSRLCSH---FKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFE 1134
            M+T  N   +++SDFI++EKIGEGTYGVVYK KNK  G FAALKKIRLENDE+GVPSTAIREISLLKEL HPNIV L+Q +M++G+L+LVFEYLN+DL+RYLD+   +  ++P ++K F+YQ+LQGLLFCH RRVIHRDLKPQN+LVD    I+KLADFGLAR FG+PV+ LTHE                   VVTLWYRAPEIL+G++RYSCAVD+WS+ CIF+E++T + LFRGDSEIDQ+F+IF LLGTP+E  WPGVS L  +     P+W  S+L       K F SP GLDL+  ML+Y P  RI +RDALLH YF++L++S +PA GEE+   P +
Sbjct:    1 MSTRGN---YALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNLDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHE-------------------VVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPIWRNSKLSIQDNIAKAFTSP-GLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEEYIGLPLD 321
[Close]
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A095BXJ3 (Cyclin-dependent kinase 1 OS=Schistosoma haematobium OX=6185 GN=MS3_01917 PE=3 SV=1)

HSP 1 Score: 421.009 bits (1081), Expect = 3.654e-142
Identity = 208/344 (60.47%), Postives = 260/344 (75.58%), Query Frame = 1 
Query:  121 MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDN--LQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM-LPLWTTSRLCSH---FKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFE 1134
            M+T  N   +++SDFI++EKIGEGTYGVVYK KNK  G FAALKKIRLENDE+GVPSTAIREISLLKEL HPNIV L+Q +M++G+L+LVFEYLN+DL+RYLD+   +  ++P ++K F+YQ+LQGLLFCH RRVIHRDLKPQN+LVD    I+KLADFGLAR FG+PV+ LTHE                   VVTLWYRAPEIL+G++RYSCAVD+WS+ CIF+E++T + LFRGDSEIDQ+F+IF LLGTP+E  WPGVS L  +     P+W  S+L       K F SP GLDL+  ML+Y P  RI +RDALLH YF++L++S +PA GEE+   P +
Sbjct:    1 MSTRGN---YALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNLDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHE-------------------VVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPVWRNSKLSIQDNIAKAFTSP-GLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEEYIGLPLD 321
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 384.03 bits (985), Expect = 1.293e-132
Identity = 183/319 (57.37%), Postives = 239/319 (74.92%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            + D++KIEKIGEGTYGVVYKG++K TG   ALKKIRLE++E+GVPSTA+REISLLKEL HPN+V L   +MQ+ KL+LVFE+L+MDL++YLD++     MDPM++K ++YQIL+G+LFCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF +LGTP  + WP V  L  + +  P W T  L S  K+ +  +G+DL+ +ML+Y+P  RI++R A+ H YF +L+++ LPA+
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKN-LDKNGIDLLGKMLIYDPLKRISARQAMTHPYFDDLDKTTLPAN 298
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 384.03 bits (985), Expect = 1.293e-132
Identity = 183/319 (57.37%), Postives = 239/319 (74.92%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            + D++KIEKIGEGTYGVVYKG++K TG   ALKKIRLE++E+GVPSTA+REISLLKEL HPN+V L   +MQ+ KL+LVFE+L+MDL++YLD++     MDPM++K ++YQIL+G+LFCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF +LGTP  + WP V  L  + +  P W T  L S  K+ +  +G+DL+ +ML+Y+P  RI++R A+ H YF +L+++ LPA+
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKN-LDKNGIDLLGKMLIYDPLKRISARQAMTHPYFDDLDKTTLPAN 298
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 349.747 bits (896), Expect = 1.683e-119
Identity = 168/288 (58.33%), Postives = 214/288 (74.31%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEM 1011
            + D++KIEKIGEGTYGVVYKG++K TG   ALKKIRLE++E+GVPSTA+REISLLKEL HPN+V L   +MQ+ KL+LVFE+L+MDL++YLD++     MDPM++K ++YQIL+G+LFCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF +LGTP  + WP V  L  + +  P W T  L S  K+ +  +G+DL+  +
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKN-LDKNGIDLLGSV 267
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 345.125 bits (884), Expect = 1.971e-117
Identity = 175/320 (54.69%), Postives = 227/320 (70.94%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQ-GLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            + D++KIEKIGEGTYGVVYKG++K TG   ALKKIRLE++E+GVPSTA+REISLLKEL HPN+V L   +MQ+ KL+LVFE+L+MDL++YLD++     MDPM++      +   G+LFCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VDVWS+  IFAE+AT KPLF GDSEIDQ+F+IF +LGTP  + WP V  L  + +  P W T  L S  K+ +  +G+DL + + L     RI++R A+ H YF +L+++ LPA+
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVDLINLCVSSCGILFCHCRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKN-LDKNGIDLSNVLNLLC---RISARQAMTHPYFDDLDKTTLPAN 296
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk2 (cyclin dependent kinase 2 [Source:NCBI gene;Acc:103028318])

HSP 1 Score: 330.487 bits (846), Expect = 1.069e-111
Identity = 167/316 (52.85%), Postives = 216/316 (68.35%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLP 1098
            +  F K+EKIGEGTYGVVYK KNK TG+  ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L   +  + KL+LVFE+L+ DL++++D+   +   + ++K +++Q+LQGL FCH  RV+HRDLKPQNLL++A G  IKLADFGLAR FGVPV+  THE                   VVTLWYRAPEIL+G K YS AVD+WS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  WPGV+ +  +    P W    L       +  DG DL+ +ML Y+P  RI++++AL+H +F ++     P
Sbjct:    4 MESFQKVEKIGEGTYGVVYKAKNKITGETVALKKIRLDTETEGVPSTAIREISLLKELSHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDSSSVTGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGE-IKLADFGLARAFGVPVRTYTHE-------------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDETVWPGVTSMPDYKPSFPKWALQDLAKVVPP-LDEDGRDLLGQMLNYDPNKRISAKNALVHRFFRDVTMPMPP 298
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1])

HSP 1 Score: 333.183 bits (853), Expect = 1.500e-113
Identity = 165/300 (55.00%), Postives = 211/300 (70.33%), Query Frame = 1 
Query:  190 GTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVI--KCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFAN 1077
            G+YGVVYKG+NK TGD  ALKKIRLE++E+GVP+TAIREI+LL+EL HPNIV L+  ++Q  +L+L+FEYL MDL+RYLD +     M+P +I  + +++QILQ ++FCH RRV+HRDLKPQNLL+D  G  IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+G+ RYS  VD+WSV  I AEM   +PLF GDSEIDQ+F+IF +LGTPT   WP V  L  +    P W  S L +H    ++ DG+DL+ +ML Y+P  RI+++ AL H YF N
Sbjct:    1 GSYGVVYKGRNKGTGDLVALKKIRLEHEEEGVPATAIREIALLRELRHPNIVRLQDVLLQSARLYLIFEYLPMDLKRYLDAIPAGHCMEPPLIQGQSYLHQILQAVVFCHSRRVLHRDLKPQNLLIDRHGH-IKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGTPRYSTPVDMWSVGTILAEMVNKRPLFHGDSEIDQLFRIFRILGTPTTEVWPDVVTLPDYKPSFPKWVPSGLVAHVPG-LNQDGIDLLEKMLTYDPARRISAKRALTHPYFQN 279
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 330.487 bits (846), Expect = 2.257e-112
Identity = 167/312 (53.53%), Postives = 215/312 (68.91%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNR 1086
            + +F K+EKIGEGTYGVVYK +NK TG+  ALKKIRL+ + +GVPSTAIREISLL+EL HPNIV L   +  + KL+LVFE L+ DL++++DN   S  P+ ++K ++YQ+LQG+ FCH  R++HRDLKPQNLL++A G  IKLADFGLAR FGVP +  THE                   VVTLWYRAPEIL+G K YS +VDVWS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  WPGVS L  + S  P W    L +     ++ +G DL++ ML Y+P  R+ +  AL H +F N+ +
Sbjct:    1 MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGA-IKLADFGLARAFGVPQRTYTHE-------------------VVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPRWANQEL-TKVVPTLNFEGRDLLALMLQYDPNQRVTANMALSHCFFQNVKQ 291
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 320.857 bits (821), Expect = 1.356e-108
Identity = 166/310 (53.55%), Postives = 213/310 (68.71%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDN---LQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            F K+EKIGEGTYGVVYK ++K TGD  ALKKIRL+ + +GVPSTAIREI+LL+EL HPNIV L   +  + KL+LVFE+L+ DL++Y+DN   L  S+ P+V K +++Q+LQG+ FCH +R +HRDLKPQNLL++A G  IKLADFGLAR FGVP++  THE                   VVTLWYRAPEIL+G K YS AVDVWS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  W G++ L  +    P W    L +     +   G DL+ +ML Y+P  R++++ AL H +F NL 
Sbjct:    4 FQKVEKIGEGTYGVVYKARHKMTGDTVALKKIRLDTETEGVPSTAIREIALLRELNHPNIVRLLDVIHSETKLYLVFEFLDQDLKKYMDNAPPLGISL-PLV-KSYMHQLLQGIAFCHAQRTLHRDLKPQNLLINADGA-IKLADFGLARAFGVPLRTYTHE-------------------VVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDETVWQGITQLPDYKPSFPRWCAQDL-TKVVPLLDAAGHDLLMQMLQYDPTRRVSAKAALNHHFFHNLE 290
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008013.1 (pep scaffold:Pmarinus_7.0:GL478839:10839:40406:1 gene:ENSPMAG00000007231.1 transcript:ENSPMAT00000008013.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 273.863 bits (699), Expect = 1.061e-87
Identity = 143/310 (46.13%), Postives = 196/310 (63.23%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM-LPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            +  + K++K+GEGTY  VYKG++K T +  ALK+IRLE++E G P TAIRE+SLLK+L H NIVTL   +  D  L LVFEYL  DL++Y+D+    M    +K F+ Q+L+GL +CH RRV+HRDLKPQNLL++  G  +KLADFGLAR   VP K  ++E                   VVTLWYR P++L+GS  YS  +D+W V CIF EMA  +PLF G +  D++  IF +LG+P E+ WPG+S    + S   P + +  + +H    +  DGLDL+S+ LLY    RI++ DAL   YF + 
Sbjct:  195 LETYTKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHEE-GAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLEKDLKQYMDDCGNIMSMHNVKIFLLQLLRGLAYCHKRRVLHRDLKPQNLLINDKGE-LKLADFGLARAKSVPTKTYSNE-------------------VVTLWYRPPDVLLGSTEYSTQIDMWGVGCIFFEMAAGRPLFPGSTVEDELHLIFRMLGSPREDMWPGISSNEEYKSYNFPKYRSEPMITHAPR-LDVDGLDLLSKFLLYEAKARISAEDALKRPYFKSF 482
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk7 (cyclin-dependent kinase 7 [Source:ZFIN;Acc:ZDB-GENE-010320-2])

HSP 1 Score: 223.787 bits (569), Expect = 6.469e-70
Identity = 119/315 (37.78%), Postives = 176/315 (55.87%), Query Frame = 1 
Query:  169 KIEKIGEGTYGVVYKGKNKKTGDFAALKKIRL---ENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAH 1104
            KI+ +GEG +  VYK  +K T    A+KKI+L      +DG+  TA+REI LL+EL HPNI+ L  +      + LVF++++ DL   + +    + P  IK F+   LQGL + H+  ++HRD+KP NLL+D  G ++KLADFGLA++FG P +  TH                   QVVT WYR+PE+L G++ Y   VD+W+V CI AE+    P   GDS++DQ+ KIF  LGTPTE  WPG+++L  +        T     +     + D L+L+  +  ++P  R+ +  A+   YF+N      PA 
Sbjct:   28 KIDFLGEGQFATVYKAMDKVTNKIVAIKKIKLGHRTEAKDGINRTALREIKLLQELNHPNIIGLLDAFGHKSNISLVFDFMDTDLEVIVKDTSLVLSPANIKSFMVMTLQGLEYLHMHWILHRDMKPNNLLLDEQG-VLKLADFGLAKSFGSPSRVYTH-------------------QVVTRWYRSPELLFGARMYGVGVDMWAVGCILAELLLRTPFLPGDSDLDQLSKIFEALGTPTEELWPGMTNLPDYVEYKSFPGTP--LENIFTAATDDLLELLQGLFTFSPAARLTATQAMQMPYFSNRPGPTPPAQ 320
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: CDC28 (Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364])

HSP 1 Score: 300.442 bits (768), Expect = 7.490e-101
Identity = 152/313 (48.56%), Postives = 209/313 (66.77%), Query Frame = 1 
Query:  151 SISDFIKIEKIGEGTYGVVYKGKNKKTGD---FAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDG-KLFLVFEYLNMDLRRYLDNL--QCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYF 1071
             ++++ ++EK+GEGTYGVVYK  + + G      ALKKIRLE++++GVPSTAIREISLLKEL   NIV L   +  D  KL+LVFE+L++DL+RY++ +     +   ++K F+ Q+ +G+ +CH  R++HRDLKPQNLL++  G + KL DFGLAR FGVP++A THE+                   VTLWYRAPE+L+G K+YS  VD WS+ CIFAEM   KP+F GDSEIDQIFKIF +LGTP E  WP + +L  +    P W    L S     + P G+DL+ ++L Y+P +RI++R A +H YF
Sbjct:    4 ELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNL-KLGDFGLARAFGVPLRAYTHEI-------------------VTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDL-SQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYF 295
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952])

HSP 1 Score: 269.24 bits (687), Expect = 1.817e-88
Identity = 141/317 (44.48%), Postives = 200/317 (63.09%), Query Frame = 1 
Query:  151 SISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-----VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSML----PLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFA 1074
            S S F ++EK+G GTY  VYKG NK TG + ALK+++L+++E G PSTAIREISL+KEL H NIV L   +  + KL LVFE+++ DL++Y+D+      P      ++K F +Q+LQGL FCH  +++HRDLKPQNLL++  G + KL DFGLAR FG+PV   + EV                   VTLWYRAP++LMGS+ YS ++D+WS  CI AEM T KPLF G ++ +Q+  IF ++GTP E+ WP V+ L  +N  +    P      L  H K+ +  + +D +  +L  NP  R++++ AL H +FA
Sbjct:    3 SSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEE-GTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQL-KLGDFGLARAFGIPVNTFSSEV-------------------VTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFA 298
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: KIN28 (Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266])

HSP 1 Score: 199.519 bits (506), Expect = 2.309e-61
Identity = 118/316 (37.34%), Postives = 163/316 (51.58%), Query Frame = 1 
Query:  160 DFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM--LPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            ++ K +K+GEGTY VVY G    TG   A+K+I+    +DG+  +AIRE+  L+E+ HPN++ L    M    L LV E+L  DL   + +      P  IK ++   L+G+  CH   ++HRDLKP NLL    G  IK+ADFGLAR    P + LT                   + VVT WYRAPE+L G+K Y+ A+D+WSV  IFAE+    P   G +++DQ+   F  LGTPT+  WP VS   ++N +   P  +   L   F    S   LD +  ML  NP  R  +   L   YF  L     P+
Sbjct:    6 EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQ-IKVADFGLARAIPAPHEILT-------------------SNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIA-ASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSDPS 300
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: CTK1 (Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622])

HSP 1 Score: 201.83 bits (512), Expect = 6.006e-60
Identity = 109/312 (34.94%), Postives = 171/312 (54.81%), Query Frame = 1 
Query:  151 SISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGK-LFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTT---SRLCSHFKDFM-SPDGLDLISEMLLYNPPDRINSRDALLHSYF 1071
            S S +++I ++GEGTYG VYK KN  T    ALKK+RL+ + +G P T+IREI LL+   HPN+ T+K+ M++  K ++++FEY + DL   L N +  +     K    Q+L G+ + H  +++HRD+K  N+L+D  G + K+ DFGLAR                           +  +V+TLWYR PE+L+G+  Y   VD+W   C+  E+     +F+G +E++QI  IF ++GTPT N WP +  +  +  ++P  TT   +     FK  + S   L L   +L Y+   R ++ +AL   YF
Sbjct:  179 STSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNL-KITDFGLARKMN--------------------SRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYF 469
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: SGV1 (Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365])

HSP 1 Score: 190.274 bits (482), Expect = 1.195e-54
Identity = 127/350 (36.29%), Postives = 188/350 (53.71%), Query Frame = 1 
Query:  175 EKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQD--------------GKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLAR-TFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTS---RLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFEASQKSKFNKVKE 1170
            EK+G+GT+G VYKG + +T    A+KKI +  ++D  P TA REI++LK L H NI+ L + M+ D                 +++  Y+  DL   L N + +++   IK  + QIL+GL + H  + +HRD+K  N+L+D  G ++KLADFGLAR  +G P          LK         K+ + VVT WYRAPE+++G K+Y+ AVD+W V C+FAE    KP+ +G ++IDQ   IF LLGTPTE  W    +L        L TT+    L   F  ++S  GLD + ++L  +P  R+ +  A  H +F       LP+   E    P E S ++   + KE
Sbjct:   64 EKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIE-MVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNG-VLKLADFGLARLYYGCPPN--------LKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAE----LTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFK---EDPLPS---EKITLPTEESHEADIKRYKE 393
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO43671 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXS1])

HSP 1 Score: 351.673 bits (901), Expect = 3.176e-120
Identity = 172/309 (55.66%), Postives = 219/309 (70.87%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIH-PNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFAN 1077
            + DF KIEKIGEGTYGVVYK KN KTG FAALKKIRLE +++G+PSTA+REISLLKEL H PN+V L+  + Q+ KL+LVFEYL  DL+++LD  +  +D  ++K ++YQI   + FCH RR++HRDLKPQNLL+D+ G +IKLADFGL R FG+PV+A THEV                   VTLWYRAPE+L+G +RYSC +DVWS+  IFAEM T +PLF GDSEIDQ+F+IF +LGTPTE  W GV+ L  +    P W    L        S DGLDL+ +ML+Y+P  RI+++ +L H YF N
Sbjct:    1 MDDFSKIEKIGEGTYGVVYKAKNLKTGGFAALKKIRLEVEDEGIPSTAVREISLLKELRHHPNVVELQHILHQEPKLYLVFEYLTCDLKKHLDTTRGMLDKTLVKSYLYQITNAIYFCHARRILHRDLKPQNLLIDSKG-LIKLADFGLGRAFGIPVRAYTHEV-------------------VTLWYRAPEVLLGGQRYSCPIDVWSIGTIFAEMVTKRPLFHGDSEIDQLFRIFRILGTPTEETWKGVTSLPDYKPTFPKWAGDGLKKAVPQLDS-DGLDLLKKMLIYDPALRISAKTSLKHPYFLN 288
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO41403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F0])

HSP 1 Score: 329.331 bits (843), Expect = 1.001e-111
Identity = 165/315 (52.38%), Postives = 213/315 (67.62%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS-MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQL 1095
            + +F K+EKIGEGTYGVVYK ++K TG   ALKKIRL+ + +GVPSTAIREISLLKEL HPN+V+L   +     L+LVFE+L+ DL++Y+D L  S +   +IK +VYQ+L G+ +CH  RV+HRDLKPQNLL+D  G  IKLADFGLAR FGVPV++ THE                   VVTLWYRAPEIL+GS+ Y+  VDVWS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP +  WPGVS L  + +  P W    +  H    +    +DL+ +ML Y P  RI+++ AL H +F ++ R  L
Sbjct:    1 MENFEKVEKIGEGTYGVVYKARDKTTGRMVALKKIRLDTESEGVPSTAIREISLLKELNHPNVVSLLDVVHNQKSLYLVFEFLSQDLKKYMDCLPPSGISTSLIKSYVYQLLSGVAYCHSHRVLHRDLKPQNLLIDKNGA-IKLADFGLARAFGVPVRSYTHE-------------------VVTLWYRAPEILLGSRYYATPVDVWSIGCIFAEMKTRRALFPGDSEIDQLFRIFRTLGTPDDKVWPGVSELPDYKTSFPKWPVQSI-RHVLPTLDNTAIDLLQKMLTYQPNARISAKAALSHEFFKDVQRKIL 294
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO49420 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGF7])

HSP 1 Score: 297.745 bits (761), Expect = 2.612e-99
Identity = 150/311 (48.23%), Postives = 208/311 (66.88%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMAT-TKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            +  + K+EKIGEGTYG V+KGKNK+T +  ALK++RL++D++GVPS+A+REI LLKEL H NIV L   +  + KL LVFE+ + DL++Y D+ Q  +D  V+K F++Q+L+GL FCH   V+HRDLKPQNLL++  G  +KLADFGLAR FG+PV+  + E                   VVTLWYR P++LMG+K YS ++D+WS  CIFAEMA   +PLF G+   DQ+ +IF +LGTPTE  WP VS L  +    P   +  L       +S  G DL+ ++L+ NP  RI++ DA+ H+YFA+L+
Sbjct:    1 MQKYDKLEKIGEGTYGTVFKGKNKETREILALKRVRLDDDDEGVPSSALREICLLKELKHNNIVRLYDVLHSEKKLTLVFEFCDQDLKKYFDSCQGEVDASVVKSFMFQLLRGLAFCHSHNVLHRDLKPQNLLINKDGE-LKLADFGLARAFGIPVRCFSAE-------------------VVTLWYRPPDVLMGAKLYSTSIDMWSAGCIFAEMANGGRPLFPGNDVDDQLRRIFKILGTPTEESWPNVSKLPDYKEFPPQGPSVSLGMVVPK-LSSTGRDLLQKLLVSNPAHRISAEDAMKHAYFADLS 290
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO48117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK70])

HSP 1 Score: 263.077 bits (671), Expect = 2.448e-85
Identity = 139/308 (45.13%), Postives = 194/308 (62.99%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSW-NSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            + K++K+GEGTY  V+KGK+K T +  ALK+IRLE++E G P TAIRE+SLLK L H NIVTL  ++     L LVFEYL  DL++Y+D+    M    ++ F++Q+L+GL +CH R+V+HRDLKPQNLL++  G  +KLADFGLAR   VP K  ++E                   VVTLWYR P++L+GS  YS  +D+W V CIF EMAT +PLF G +  D++  IF +LGTP+E  WPG+S   ++     P +    L  H    +   GL+L+ + L Y   DR+++ DA+ H YF +L 
Sbjct:   11 YTKLDKLGEGTYATVFKGKSKLTDNIVALKEIRLEHEE-GAPCTAIREVSLLKGLKHANIVTLHDTVHTQKSLTLVFEYLEKDLKQYMDDCGGIMSMNNVRIFLFQLLRGLDYCHKRKVLHRDLKPQNLLINDKGE-LKLADFGLARAKSVPTKTYSNE-------------------VVTLWYRPPDVLLGSTAYSTQIDMWGVGCIFFEMATGRPLFPGSTVEDELLLIFKVLGTPSEEVWPGISANEAFIAGKFPDYPRENLIIHAPR-LDNSGLELLEKFLEYTVKDRVSAHDAMRHDYFYSLG 296
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO29995 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T226])

HSP 1 Score: 247.284 bits (630), Expect = 1.645e-78
Identity = 137/341 (40.18%), Postives = 196/341 (57.48%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQD--GKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFAN----LNRSQLPAHGEEHR----ASPFEASQK 1146
            +++F K+ +IGEGTYG+VY+ K+ K+G   ALKK+R+E + DG+P + +REI+LL  L H NIV L + ++      LFL  EY   D+   LDN+ C      IKC + Q+L+G  + H   ++HRDLK  NLL+   G ++K+ADFGLARTFG P K +T                     VVTLWYR+PE+L+G+K ++ AVD+W+V CIF E+   KPL  G SEI+Q+  I  LLGTP ++ WPG S L    S+           H   ++S  GL L++ ML+Y+P  R  + ++L  SYF      ++   +P    EHR     SP E  +K
Sbjct:   33 VAEFEKLNRIGEGTYGIVYRAKDTKSGKIVALKKVRMEQERDGIPISGLREITLLLNLRHENIVQLLEVVVGKHLDSLFLSMEYCEQDIASLLDNMSCPFSEAQIKCLMIQLLEGTKYLHEHFIVHRDLKVSNLLLTGKG-VLKIADFGLARTFGYPYKPMT-------------------PVVVTLWYRSPELLLGAKVHTTAVDMWAVGCIFGELLGNKPLLAGKSEINQLQLIVDLLGTPNDHIWPGYSSLPGVKSISLKHQPYNNLKHKFSWVSQAGLSLLNYMLMYDPCKRATAAESLQSSYFVEKPLPVDADMMPTF-PEHRNFKNRSPTEGVEK 352
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:100049478])

HSP 1 Score: 383.645 bits (984), Expect = 1.584e-132
Identity = 181/318 (56.92%), Postives = 237/318 (74.53%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCS--MDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPA 1101
            + D++KIEKIGEGTYGVVYKG++K TG   A+KKIRLE++E+GVPSTA+RE+SLL+EL HPN+V L   +MQ+ +L+L+FE+L+MDL++YLD++     MDPM++K ++YQIL+G+ FCH RRV+HRDLKPQNLL+D  G +IKLADFGLAR FGVPV+  THE                   VVTLWYRAPE+L+GS RYS  VDVWS   IFAE+AT KPLF GDSEIDQ+F+IF  LGTP  + WP V  L  + +  P W    L S  K+ +  +GLDL+++ML+YNPP RI++R+A+ H YF +L++S LPA
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKG-VIKLADFGLARAFGVPVRVYTHE-------------------VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWKEGSLSSMVKN-LDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPA 297
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk2 (cyclin dependent kinase 2 [Source:NCBI gene;Acc:101161880])

HSP 1 Score: 337.421 bits (864), Expect = 1.985e-114
Identity = 168/308 (54.55%), Postives = 217/308 (70.45%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            F K+EKIGEGTYGVVYK KNK TG+  ALKKIRL+ + +GVPSTAIREISLLKEL HPNIV L+  +  + KL+LVFE+L+ DL++++D+   +  P+ ++K +++Q+LQGL FCH  RV+HRDLKPQNLL++A G  IKLADFGLAR FGVPV+  THE                   VVTLWYRAPEIL+G K YS AVDVWS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  WPGV+ +  +    P W    L S     +  DG +L+ EML Y+P  R+++++AL+H +F ++ 
Sbjct:    4 FQKVEKIGEGTYGVVYKAKNKLTGETVALKKIRLDTETEGVPSTAIREISLLKELSHPNIVKLQDVIHTENKLYLVFEFLHQDLKKFMDSSSVTGIPLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGE-IKLADFGLARAFGVPVRTYTHE-------------------VVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDETAWPGVTSMPDYKPSFPKWARQDL-SKVVPLLDEDGRELLGEMLKYDPNKRLSAKNALVHRFFRDVT 290
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk5 (cyclin dependent kinase 5 [Source:NCBI gene;Acc:101174461])

HSP 1 Score: 293.508 bits (750), Expect = 2.634e-97
Identity = 146/310 (47.10%), Postives = 203/310 (65.48%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATT-KPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            +  + K+EKIGEGTYG V+K KN++T +  ALK++RL++D++GVPS+A+REI LLKEL H NIV L   +  D KL LVFEY + DL++Y D+    +DP  +K F+YQ+L+GL FCH R V+HRDLKPQNLL++  G  +KLADFGLAR FG+PV+  + E                   VVTLWYR P++L G+K YS ++D+WS  CIFAE+A   +PLF G+   DQ+ +IF LLGTPTE  WP ++ L  +    P++  +    +    +S  G DL+  +L  NP  RI++ +AL H YFA+ 
Sbjct:    1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPETVKSFMYQLLKGLAFCHSRNVLHRDLKPQNLLINRNGE-LKLADFGLARAFGIPVRCYSAE-------------------VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPTMTKLPDYKPY-PMYPATTSLVNVVPKLSNTGRDLLQNLLKCNPVQRISAEEALQHPYFADF 289
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk2 (cyclin dependent kinase 2 [Source:NCBI gene;Acc:101161880])

HSP 1 Score: 283.878 bits (725), Expect = 8.806e-94
Identity = 149/308 (48.38%), Postives = 197/308 (63.96%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPM-VIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            F K+EKIGEGTYGVVYK KNK TG+  ALKKIRL+                L+++IH            + KL+LVFE+L+ DL++++D+   +  P+ ++K +++Q+LQGL FCH  RV+HRDLKPQNLL++A G I KLADFGLAR FGVPV+  THEV                   VTLWYRAPEIL+G K YS AVDVWS+ CIFAEM T + LF GDSEIDQ+F+IF  LGTP E  WPGV+ +  +    P W    L S     +  DG +L+ EML Y+P  R+++++AL+H +F ++ 
Sbjct:    4 FQKVEKIGEGTYGVVYKAKNKLTGETVALKKIRLDT---------------LQDVIH-----------TENKLYLVFEFLHQDLKKFMDSSSVTGIPLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGEI-KLADFGLARAFGVPVRTYTHEV-------------------VTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDETAWPGVTSMPDYKPSFPKWARQDL-SKVVPLLDEDGRELLGEMLKYDPNKRLSAKNALVHRFFRDVT 264
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: ENSORLT00000011316.2 (cyclin-dependent kinase 17 [Source:NCBI gene;Acc:101161555])

HSP 1 Score: 277.715 bits (709), Expect = 1.210e-88
Identity = 145/310 (46.77%), Postives = 199/310 (64.19%), Query Frame = 1 
Query:  154 ISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSM-LPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANL 1080
            +  +IK++K+GEGTY  V+KG++K T +  ALK+IRLE++E G P TAIRE+SLLK+L H NIVTL   +  D  L LVFEYL  DL++Y+D+    M    +K F+YQ+L+GL +CH R+V+HRDLKPQNLL+   G  +KLADFGLAR   VP K  ++E                   VVTLWYR P++L+GS  YS  +D+W V CIF EM T +PLF G +  D++  IF +LGTPTE  WPG+     + +   PL+    L +H     S DG DL+S++L ++   R+++ DAL HSYF +L
Sbjct:  138 LETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEE-GAPCTAIREVSLLKDLKHANIVTLHDIIHTDKCLTLVFEYLEKDLKQYMDDCGNIMSVNNVKIFLYQLLRGLAYCHRRKVLHRDLKPQNLLISEKGE-LKLADFGLARAKSVPTKTYSNE-------------------VVTLWYRPPDVLLGSTEYSTPIDMWGVGCIFYEMITGRPLFPGSTVEDELHLIFRVLGTPTEKTWPGMPTSEEFKTYNFPLYRAEPLVNHAPRIDS-DGHDLLSKLLQFDAKKRVSAEDALKHSYFRSL 425
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000052421.1 (SMESG000052421.1)

HSP 1 Score: 702.59 bits (1812), Expect = 0.000e+0
Identity = 341/360 (94.72%), Postives = 341/360 (94.72%), Query Frame = 1 
Query:  121 MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFEASQKSKFNKVKENNFMDTPTIK 1200
            MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEV                   VTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFEASQKSKFNKVKENNFMDTPTIK
Sbjct:    1 MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEV-------------------VTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFEASQKSKFNKVKENNFMDTPTIK 341
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000052413.1 (SMESG000052413.1)

HSP 1 Score: 395.586 bits (1015), Expect = 5.855e-137
Identity = 191/328 (58.23%), Postives = 237/328 (72.26%), Query Frame = 1 
Query:  142 VKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRAS 1125
            + + +SDF +IEKIGEGTYG+VYK  NK T +FAA+KKIR ENDEDG+  T +REIS+LKEL HPNIV L+Q++ + GKL+LVFEYLNMDLRRYLDN +  M+ +++K F YQI+QGLL+CH RR +HRDLKPQNLLVD    IIKLADFGLAR +G PVK LTHE                   VVTLWYRAPE+++ +KRYSCA+DVWSVACI AEM T KPLFRGDSEIDQ+F IF +LGTP    WP +     WN + P+W    L S   + +  +  DL+ +ML+Y+P +R N RDALLH YFA+L++S LPA   E + S
Sbjct:    1 MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHE-------------------VVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYD-LRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERKYS 308
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000074437.1 (SMESG000074437.1)

HSP 1 Score: 291.967 bits (746), Expect = 8.499e-97
Identity = 137/291 (47.08%), Postives = 200/291 (68.73%), Query Frame = 1 
Query:  247 LKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHR 1119
            LK+I+L+ +E G+  T +REIS+LK L HPNIV+L++ ++   KL++VFE+++MDL+ +   L   ++  +I+  +YQ+LQGLL+CH RRVIHRDLKPQN+LV+ TGT++KLADFGL R +G+P K +T                   T+++T WYRAPEI++G+K Y+C+VD+WSV CIFAE+A   PLF GDSEI Q+FKIF + GTP  N       L  W  + P WT + L      ++S  G+DL+S++L+YNP +R+NS+D LLH YF + +++ +PA  EE +
Sbjct:    3 LKRIKLDGNE-GIQCTTLREISILKNLQHPNIVSLEKVILLPNKLYMVFEFIDMDLQAFALRLDTGLNSEIIRSIMYQLLQGLLYCHKRRVIHRDLKPQNILVNKTGTLVKLADFGLGRIYGIPSKKMT-------------------TEIITQWYRAPEIILGAKTYNCSVDMWSVGCIFAELALGAPLFNGDSEIGQLFKIFQINGTPDANSI--FIRLEKWQDVFPNWTGTTLSVKMDGYLSKIGIDLLSKLLVYNPLERLNSQDTLLHDYFLDFDKTTVPASNEECK 271
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000000804.1 (SMESG000000804.1)

HSP 1 Score: 281.952 bits (720), Expect = 7.960e-93
Identity = 143/308 (46.43%), Postives = 200/308 (64.94%), Query Frame = 1 
Query:  163 FIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMAT-TKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLN 1083
            F K+EKIGEGTYG V+K KN+++ +  ALK++RL+ D++G+PS+A+REI LLKEL HPNIV L   ++ D +L +VFEY + DL++Y D+    +D   +K F+YQ+L+GL +CH   V+HRDLKPQNLL++  G  +KLADFGLAR FG+PV+  + E                   VVTLWYR P++L G+K YS  +D+WS  CIFAEM+   +PLF G+   DQ+ +IF  LGTPTE+ WPGV+ L  +      +  +   S     +S  G DL+ ++L+  P DRINS  AL H YF + +
Sbjct:    9 FEKLEKIGEGTYGTVFKAKNRESFEIVALKRVRLDEDDEGIPSSALREICLLKELKHPNIVKLIDVLLSDRRLTMVFEYCDQDLKKYFDSCNGEIDQNTVKSFMYQLLRGLHYCHSHNVLHRDLKPQNLLINDNGE-LKLADFGLARAFGIPVRQYSAE-------------------VVTLWYRPPDVLFGAKLYSTTIDMWSAGCIFAEMSNGGRPLFPGNDVDDQLKRIFKFLGTPTEDIWPGVTQLPEY-KQFSYYPCNPNWSQGVPKLSSKGRDLLQKLLVCCPADRINSDLALSHVYFESFH 295
[Close]
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000074437.1 (SMESG000074437.1)

HSP 1 Score: 250.751 bits (639), Expect = 1.843e-81
Identity = 120/253 (47.43%), Postives = 171/253 (67.59%), Query Frame = 1 
Query:  247 LKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVXXXXXXXXXXXXXXXXTQVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLIS 1005
            LK+I+L+ +E G+  T +REIS+LK L HPNIV+L++ ++   KL++VFE+++MDL+ +   L   ++  +I+  +YQ+LQGLL+CH RRVIHRDLKPQN+LV+ TGT++KLADFGL R +G+P K +T                   T+++T WYRAPEI++G+K Y+C+VD+WSV CIFAE+A   PLF GDSEI Q+FKIF + GTP  N       L  W  + P WT + L      ++S  G+DL+S
Sbjct:    3 LKRIKLDGNE-GIQCTTLREISILKNLQHPNIVSLEKVILLPNKLYMVFEFIDMDLQAFALRLDTGLNSEIIRSIMYQLLQGLLYCHKRRVIHRDLKPQNILVNKTGTLVKLADFGLGRIYGIPSKKMT-------------------TEIITQWYRAPEIILGAKTYNCSVDMWSVGCIFAELALGAPLFNGDSEIGQLFKIFQINGTPDANSI--FIRLEKWQDVFPNWTGTTLSVKMDGYLSKIGIDLLS 233
The following BLAST results are available for this feature:
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CDK11.507e-12757.05cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:... [more]
CDK19.205e-12756.41cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:... [more]
CDK31.757e-11555.56cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:... [more]
CDK31.757e-11555.56cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:... [more]
CDK21.176e-11053.21cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk-15.560e-12353.68Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss... [more]
cdk-15.560e-12353.68Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss... [more]
cdk-25.506e-9144.77Cyclin-dependent kinase 2 [Source:UniProtKB/Swiss... [more]
cdk-57.031e-9143.97Cyclin-dependent-like kinase 5 [Source:UniProtKB/... [more]
pct-15.293e-7040.00Cyclin-dependent kinase 17 [Source:UniProtKB/Swis... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdk11.682e-12555.19gene:FBgn0004106 transcript:FBtr0080051[more]
Cdk21.275e-10050.16gene:FBgn0004107 transcript:FBtr0083922[more]
Cdk21.275e-10050.16gene:FBgn0004107 transcript:FBtr0300447[more]
Cdk21.275e-10050.16gene:FBgn0004107 transcript:FBtr0083921[more]
Cdk52.467e-9446.33gene:FBgn0013762 transcript:FBtr0087350[more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk18.463e-13357.23cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk18.463e-13357.23cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk24.834e-11454.34cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk52.652e-9646.77cyclin-dependent kinase 5 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk174.328e-8745.48cyclin-dependent kinase 17 [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cfap651.105e-13257.99cilia and flagella associated protein 65 [Source:X... [more]
cfap658.653e-12657.28cilia and flagella associated protein 65 [Source:X... [more]
cfap659.049e-12657.42cilia and flagella associated protein 65 [Source:X... [more]
cdk21.271e-11253.02cyclin-dependent kinase 2 [Source:NCBI gene;Acc:49... [more]
cfap651.559e-10850.80cilia and flagella associated protein 65 [Source:X... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdk13.998e-12756.73cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:M... [more]
Cdk13.998e-12756.73cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:M... [more]
Cdk24.280e-11253.65cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:M... [more]
Cdk31.396e-11154.75cyclin-dependent kinase 3 [Source:MGI Symbol;Acc:M... [more]
Cdk23.855e-10246.67cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P51958|CDK1_CARAU1.515e-13357.86Cyclin-dependent kinase 1 OS=Carassius auratus OX=... [more]
sp|Q9DGD3|CDK1_ORYLA1.420e-13156.92Cyclin-dependent kinase 1 OS=Oryzias latipes OX=80... [more]
sp|Q9DG98|CDK1_ORYLU1.927e-13156.92Cyclin-dependent kinase 1 OS=Oryzias luzonensis OX... [more]
sp|Q9DGA2|CDK1_ORYJA2.013e-13156.92Cyclin-dependent kinase 1 OS=Oryzias javanicus OX=... [more]
sp|Q9DGA5|CDK1_ORYCU2.057e-13156.92Cyclin-dependent kinase 1 OS=Oryzias curvinotus OX... [more]
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BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3PVC98.469e-14361.86Cyclin-dependent kinase 1 OS=Schistocephalus solid... [more]
A0A183LHM52.844e-14260.47Protein kinase domain-containing protein OS=Schist... [more]
A0A183K4682.875e-14260.47Protein kinase domain-containing protein OS=Schist... [more]
A0A183NHN02.875e-14260.47Protein kinase domain-containing protein OS=Schist... [more]
A0A095BXJ33.654e-14260.47Cyclin-dependent kinase 1 OS=Schistosoma haematobi... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk11.293e-13257.37cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk11.293e-13257.37cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk11.683e-11958.33cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk11.971e-11754.69cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk21.069e-11152.85cyclin dependent kinase 2 [Source:NCBI gene;Acc:10... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk11.500e-11355.00cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk22.257e-11253.53cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk21.356e-10853.55cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
ENSPMAT00000008013.11.061e-8746.13pep scaffold:Pmarinus_7.0:GL478839:10839:40406:1 g... [more]
cdk76.469e-7037.78cyclin-dependent kinase 7 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
CDC287.490e-10148.56Cyclin-dependent kinase (CDK) catalytic subunit; m... [more]
PHO851.817e-8844.48Cyclin-dependent kinase; has ten cyclin partners; ... [more]
KIN282.309e-6137.34Serine/threonine protein kinase, subunit of transc... [more]
CTK16.006e-6034.94Catalytic (alpha) subunit of C-terminal domain kin... [more]
SGV11.195e-5436.29Cyclin (Bur2p)-dependent protein kinase; part of t... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO436713.176e-12055.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414031.001e-11152.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494202.612e-9948.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO481172.448e-8545.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO299951.645e-7840.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk11.584e-13256.92cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk21.985e-11454.55cyclin dependent kinase 2 [Source:NCBI gene;Acc:10... [more]
cdk52.634e-9747.10cyclin dependent kinase 5 [Source:NCBI gene;Acc:10... [more]
cdk28.806e-9448.38cyclin dependent kinase 2 [Source:NCBI gene;Acc:10... [more]
ENSORLT00000011316.21.210e-8846.77cyclin-dependent kinase 17 [Source:NCBI gene;Acc:1... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000052421.10.000e+094.72SMESG000052421.1[more]
SMESG000052413.15.855e-13758.23SMESG000052413.1[more]
SMESG000074437.18.499e-9747.08SMESG000074437.1[more]
SMESG000000804.17.960e-9346.43SMESG000000804.1[more]
SMESG000074437.11.843e-8147.43SMESG000074437.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029621 ID=SMED30029621|Name=Cyclin-dependent kinase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1258bp
TTTACAGAACTGTTGCGTGATTTTTATCAAGTACTATAACTTATTTCTTT
AAACTCAAAATTTTCAACTTTGGATTAAATTATTAACGGAATTGTTAAAT
ACTAAATTTTAAGTTTATAAATGGCTACAGACAATAATAACGTGAAATTT
TCTATTTCTGATTTCATTAAAATAGAAAAAATTGGCGAAGGCACTTATGG
AGTTGTATATAAGGGAAAAAATAAGAAGACTGGAGATTTTGCTGCCTTGA
AAAAGATTCGATTGGAAAACGATGAAGATGGGGTTCCATCGACAGCGATT
CGTGAAATATCCCTCCTTAAAGAATTGATTCATCCAAATATTGTCACATT
GAAACAAAGCATGATGCAAGATGGGAAATTATTTCTCGTATTTGAGTATT
TGAATATGGATTTACGCCGGTATCTTGACAATCTGCAATGCAGCATGGAT
CCAATGGTAATCAAATGTTTCGTTTATCAAATACTACAGGGATTGTTGTT
CTGTCATTTGCGACGAGTTATTCATCGAGATTTGAAACCACAAAATCTAC
TCGTCGACGCTACCGGCACAATAATCAAATTGGCCGACTTTGGTCTGGCT
CGAACATTCGGTGTGCCGGTGAAAGCTCTGACACACGAAGTGAAAATTCT
TAAACTGAAATTACTAATCGATCTAATCTGGAAACATCTAACTCAGGTCG
TTACGTTGTGGTATCGAGCACCGGAAATTTTGATGGGCTCCAAACGCTAT
TCTTGCGCGGTTGACGTTTGGTCTGTGGCGTGCATTTTCGCTGAAATGGC
AACAACTAAGCCGCTGTTTCGGGGTGACTCGGAAATCGATCAGATCTTCA
AGATATTTCATTTGCTGGGCACGCCGACCGAGAACCACTGGCCCGGAGTC
AGCCACTTGTCGAGCTGGAATTCAATGCTGCCGTTGTGGACAACCAGTCG
ATTGTGTTCCCATTTTAAGGATTTCATGTCGCCCGACGGCCTGGATTTGA
TATCGGAAATGCTTCTATATAATCCTCCAGATAGAATTAATTCTAGAGAT
GCTTTATTGCATTCGTACTTTGCTAATTTGAATAGAAGTCAGCTGCCTGC
CCACGGAGAAGAGCACAGGGCATCTCCGTTTGAAGCTTCTCAGAAATCAA
AATTTAATAAAGTCAAAGAAAATAATTTTATGGACACTCCAACAATTAAA
TAGTTAATGTTATTTGTTTATTAATAATACATTTGTTTCATGAGATTCGT
TAGTTCTG
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protein sequence of SMED30029621-orf-1

>SMED30029621-orf-1 ID=SMED30029621-orf-1|Name=SMED30029621-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=361bp
MATDNNNVKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLEN
DEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRR
YLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGT
IIKLADFGLARTFGVPVKALTHEVKILKLKLLIDLIWKHLTQVVTLWYRA
PEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLG
TPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLY
NPPDRINSRDALLHSYFANLNRSQLPAHGEEHRASPFEASQKSKFNKVKE
NNFMDTPTIK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000026gut
PLANA:0002089reproductive organ
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0016301kinase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 15..317
e-value: 5.5E-95
score: 331.5
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 16..317
e-value: 1.8E-68
score: 230.8
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 15..317
score: 43.976
NoneNo IPR availablePIRSFPIRSF000654ILKcoord: 2..248
e-value: 1.4E-22
score: 77.6
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 9..95
e-value: 1.6E-32
score: 113.2
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 96..355
e-value: 8.8E-62
score: 210.5
NoneNo IPR availablePANTHERPTHR24056:SF371coord: 191..321
NoneNo IPR availablePANTHERPTHR24056:SF371coord: 17..177
NoneNo IPR availablePANTHERPTHR24056CELL DIVISION PROTEIN KINASEcoord: 191..321
coord: 17..177
NoneNo IPR availableCDDcd07829STKc_CDK_likecoord: 15..317
e-value: 2.22003E-167
score: 466.189
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 133..145
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 21..44
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 10..321