Inhibitor of growth protein

Overview


Name	Inhibitor of growth protein
Smed ID	SMED30029420
Length (bp)	1666

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Inhibitor of growth protein (SMED30029420) t-SNE clustered cells

Violin plots show distribution of expression levels for Inhibitor of growth protein (SMED30029420) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Inhibitor of growth protein (SMED30029420) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Inhibitor of growth protein (SMED30029420) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30029420

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30029420	SMESG000015211.1	SmedASXL_008348	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30029420	SMESG000015211.1	dd_Smed_v4_6715_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING5 (inhibitor of growth family member 5 [Source:HGNC Symbol;Acc:HGNC:19421])

HSP 1 Score: 81.2629 bits (199), Expect = 1.052e-16
Identity = 31/50 (62.00%), Postives = 38/50 (76.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C  EK
Sbjct:  187 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEK 236

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING1 (inhibitor of growth family member 1 [Source:HGNC Symbol;Acc:HGNC:6062])

HSP 1 Score: 79.7221 bits (195), Expect = 1.832e-16
Identity = 28/49 (57.14%), Postives = 37/49 (75.51%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
             YC+CN+ SYG+MI CD+D+C IEWFH+ CV +   PKG W+CP C+ E
Sbjct:  142 TYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGE 190

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING1 (inhibitor of growth family member 1 [Source:HGNC Symbol;Acc:HGNC:6062])

HSP 1 Score: 80.1073 bits (196), Expect = 2.725e-16
Identity = 28/49 (57.14%), Postives = 37/49 (75.51%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
             YC+CN+ SYG+MI CD+D+C IEWFH+ CV +   PKG W+CP C+ E
Sbjct:  167 TYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGE 215

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING1 (inhibitor of growth family member 1 [Source:HGNC Symbol;Acc:HGNC:6062])

HSP 1 Score: 80.1073 bits (196), Expect = 4.837e-16
Identity = 28/49 (57.14%), Postives = 37/49 (75.51%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
             YC+CN+ SYG+MI CD+D+C IEWFH+ CV +   PKG W+CP C+ E
Sbjct:  211 TYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGE 259

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING3 (inhibitor of growth family member 3 [Source:HGNC Symbol;Acc:HGNC:14587])

HSP 1 Score: 81.6481 bits (200), Expect = 4.996e-16
Identity = 28/45 (62.22%), Postives = 35/45 (77.78%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            YCICN+ SYG+M+ CD+  C IEWFHY CV +T +PKG W+CP C
Sbjct:  347 YCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC 391

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: ing-3 (Inhibitor of growth protein [Source:UniProtKB/TrEMBL;Acc:Q9XWJ8])

HSP 1 Score: 75.485 bits (184), Expect = 2.992e-14
Identity = 25/54 (46.30%), Postives = 35/54 (64.81%), Query Frame = 2

Query:  899 DHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKI 1060
            D ED   +C CN+ SYGDM+ CD+  C + WFHY C+ +   P G W+CP C++
Sbjct:  423 DEEDEMHWCFCNEKSYGDMVQCDNRHCTLRWFHYPCIGMVEPPTGKWYCPRCEV 476

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: lsy-13 (pep chromosome:WBcel235:IV:16864655:16865476:1 gene:WBGene00020287.1 transcript:T06A10.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lsy-13)

HSP 1 Score: 54.6842 bits (130), Expect = 1.722e-8
Identity = 20/47 (42.55%), Postives = 28/47 (59.57%), Query Frame = 2

Query:  905 EDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFC 1045
            E  K+YC C       MI C++  CK  WFH+ C+ + T+P GDW+C
Sbjct:   97 EPPKMYCWCQLDKNDTMIECENPGCKYGWFHFTCIGMITAPAGDWYC 143

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: lsy-13 (pep chromosome:WBcel235:IV:16863866:16865479:1 gene:WBGene00020287.1 transcript:T06A10.4a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lsy-13)

HSP 1 Score: 55.4546 bits (132), Expect = 2.751e-8
Identity = 28/85 (32.94%), Postives = 44/85 (51.76%), Query Frame = 2

Query:  812 SNKRKRLSLSN-----SFIYNRRPRNQPNKSH--FWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFC 1045
            S+++K+LS  +     S    +R R +  +S       E  K+YC C       MI C++  CK  WFH+ C+ + T+P GDW+C
Sbjct:  134 SHRKKKLSEGDDDAPSSVDEKKRGRKKKPESEKAVAAAEPPKMYCWCQLDKNDTMIECENPGCKYGWFHFTCIGMITAPAGDWYC 218

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: lsy-13 (pep chromosome:WBcel235:IV:16862396:16865476:1 gene:WBGene00020287.1 transcript:T06A10.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lsy-13)

HSP 1 Score: 55.4546 bits (132), Expect = 2.751e-8
Identity = 28/85 (32.94%), Postives = 44/85 (51.76%), Query Frame = 2

Query:  812 SNKRKRLSLSN-----SFIYNRRPRNQPNKSH--FWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFC 1045
            S+++K+LS  +     S    +R R +  +S       E  K+YC C       MI C++  CK  WFH+ C+ + T+P GDW+C
Sbjct:  134 SHRKKKLSEGDDDAPSSVDEKKRGRKKKPESEKAVAAAEPPKMYCWCQLDKNDTMIECENPGCKYGWFHFTCIGMITAPAGDWYC 218

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: Y43H11AL.1 (pep chromosome:WBcel235:II:222704:223799:-1 gene:WBGene00021545.1 transcript:Y43H11AL.1e.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43H11AL.1)

HSP 1 Score: 47.7506 bits (112), Expect = 4.529e-7
Identity = 18/53 (33.96%), Postives = 33/53 (62.26%), Query Frame = 2

Query:  902 HEDAKVYCICNKPSY--GDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            + + + +CICN  +   G M+ C++  C I+WFH++CV +  +P  +W+C  C
Sbjct:   12 YREQEEWCICNGMNINSGMMVECENKNCPIKWFHFECVGLLAAPLDEWYCTDC 64

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BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: Ing3 (gene:FBgn0030945 transcript:FBtr0074614)

HSP 1 Score: 83.5741 bits (205), Expect = 1.635e-16
Identity = 30/45 (66.67%), Postives = 34/45 (75.56%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            YC CN+ SYGDM+ACD+D C  EWFHY CV IT  PKG W+CP C
Sbjct:  630 YCTCNQVSYGDMVACDNDACPYEWFHYPCVGITQPPKGKWYCPKC 674

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: CG7379 (gene:FBgn0038546 transcript:FBtr0083529)

HSP 1 Score: 80.8777 bits (198), Expect = 6.462e-16
Identity = 29/53 (54.72%), Postives = 38/53 (71.70%), Query Frame = 2

Query:  908 DAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
            D   YC+CN+ S+G+MI CD+D C IEWFH+ CV +   PKG WFCP C+ E+
Sbjct:  356 DEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKPKGKWFCPNCRGER 408

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: Ing5 (gene:FBgn0032516 transcript:FBtr0080525)

HSP 1 Score: 78.5666 bits (192), Expect = 8.589e-16
Identity = 28/46 (60.87%), Postives = 35/46 (76.09%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
             YC+C++ SYG+MI CD+  C IEWFH+ CV +TT PKG WFCP C
Sbjct:  233 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKPKGKWFCPKC 278

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: Ing5 (gene:FBgn0032516 transcript:FBtr0080526)

HSP 1 Score: 78.1814 bits (191), Expect = 9.656e-16
Identity = 28/46 (60.87%), Postives = 35/46 (76.09%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
             YC+C++ SYG+MI CD+  C IEWFH+ CV +TT PKG WFCP C
Sbjct:  219 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKPKGKWFCPKC 264

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: MESR4 (gene:FBgn0034240 transcript:FBtr0340220)

HSP 1 Score: 67.0106 bits (162), Expect = 3.826e-11
Identity = 27/53 (50.94%), Postives = 33/53 (62.26%), Query Frame = 2

Query:  905 EDAKVYCICNKP--SYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            E   VYC C  P     +MIACD D C IEWFH++CV I  +P+G WFC  C+
Sbjct: 2085 EGESVYCYCRCPYDEVSEMIACDGDNCLIEWFHFECVGIMVAPQGKWFCAECR 2137

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing5a (inhibitor of growth family, member 5a [Source:ZFIN;Acc:ZDB-GENE-031016-1])

HSP 1 Score: 79.7221 bits (195), Expect = 2.244e-16
Identity = 29/46 (63.04%), Postives = 36/46 (78.26%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C
Sbjct:  190 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRC 235

[Close]

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C
Sbjct:  190 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRC 235

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing3 (inhibitor of growth family, member 3 [Source:ZFIN;Acc:ZDB-GENE-040109-3])

HSP 1 Score: 82.0333 bits (201), Expect = 3.401e-16
Identity = 28/45 (62.22%), Postives = 35/45 (77.78%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            YCICN+ SYG+M+ CD+  C IEWFHY CV +T +PKG W+CP C
Sbjct:  360 YCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC 404

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing4 (inhibitor of growth family, member 4 [Source:ZFIN;Acc:ZDB-GENE-050522-47])

HSP 1 Score: 78.5666 bits (192), Expect = 6.944e-16
Identity = 27/50 (54.00%), Postives = 37/50 (74.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CV +TT P+G W+CP C  E+
Sbjct:  198 TYCLCHQVSYGEMIGCDNTDCSIEWFHFACVGLTTKPRGKWYCPRCSQER 247

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing1 (inhibitor of growth family, member 1 [Source:ZFIN;Acc:ZDB-GENE-060421-4388])

HSP 1 Score: 79.337 bits (194), Expect = 8.516e-16
Identity = 27/47 (57.45%), Postives = 36/47 (76.60%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
             YC+C + SYG+MI CD+D+C IEWFH+ CVD+   PKG W+CP C+
Sbjct:  241 TYCLCEQVSYGEMIGCDNDECTIEWFHFSCVDLHHKPKGKWYCPKCR 287

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: lman1l (lectin, mannose-binding, 1 like [Source:Xenbase;Acc:XB-GENE-5754170])

HSP 1 Score: 81.2629 bits (199), Expect = 8.944e-17
Identity = 30/50 (60.00%), Postives = 38/50 (76.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C  E+
Sbjct:  185 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCTQER 234

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: atp2b2 (ATPase, Ca++ transporting, plasma membrane 2 [Source:Xenbase;Acc:XB-GENE-950177])

HSP 1 Score: 80.8777 bits (198), Expect = 2.500e-16
Identity = 28/47 (59.57%), Postives = 37/47 (78.72%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
             YC+CN+ SYG+MI CD+D+C IEWFH+ CV +T  PKG W+CP C+
Sbjct:  212 TYCLCNQVSYGEMIGCDNDECTIEWFHFSCVGLTYKPKGKWYCPDCR 258

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: tmem192 (transmembrane protein 192 [Source:Xenbase;Acc:XB-GENE-5751968])

HSP 1 Score: 80.8777 bits (198), Expect = 1.137e-15
Identity = 27/45 (60.00%), Postives = 35/45 (77.78%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            YCICN+ SYG+M+ CD+  C IEWFHY CV ++ +PKG W+CP C
Sbjct:  361 YCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLSEAPKGKWYCPQC 405

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: ccnf (cyclin F [Source:Xenbase;Acc:XB-GENE-963729])

HSP 1 Score: 78.5666 bits (192), Expect = 1.399e-15
Identity = 27/49 (55.10%), Postives = 37/49 (75.51%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
             YC+CN+ SYG+MI CD+++C IEWFH+ CV +   PKG W+CP C+ E
Sbjct:  211 TYCLCNQVSYGEMIGCDNEECPIEWFHFSCVGLNHKPKGKWYCPECRGE 259

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: ING4 (inhibitor of growth family member 4 [Source:NCBI gene;Acc:100491241])

HSP 1 Score: 77.7962 bits (190), Expect = 3.407e-15
Identity = 37/89 (41.57%), Postives = 49/89 (55.06%), Query Frame = 2

Query:  815 NKRKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKV------YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            N +K++ L  +  Y   P     K H  D  D  V      YC+C++ SYG+MI CD+  C IEWFH+ CV + T P+G WFCP C  E
Sbjct:  197 NTQKKIKLVQTAEYGA-PAGNFGKVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLATKPRGKWFCPRCSQE 284

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing5 (inhibitor of growth family, member 5 [Source:MGI Symbol;Acc:MGI:1922816])

HSP 1 Score: 81.2629 bits (199), Expect = 4.130e-17
Identity = 31/50 (62.00%), Postives = 38/50 (76.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C  EK
Sbjct:  160 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEK 209

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing5 (inhibitor of growth family, member 5 [Source:MGI Symbol;Acc:MGI:1922816])

HSP 1 Score: 81.6481 bits (200), Expect = 5.035e-17
Identity = 31/50 (62.00%), Postives = 38/50 (76.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C  EK
Sbjct:  187 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEK 236

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing3 (inhibitor of growth family, member 3 [Source:MGI Symbol;Acc:MGI:1919027])

HSP 1 Score: 83.1889 bits (204), Expect = 1.296e-16
Identity = 32/64 (50.00%), Postives = 42/64 (65.62%), Query Frame = 2

Query:  866 PRNQPNKSHFWDHE-DAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            P +  N    W ++ +   YCICN+ SYG+M+ CD+  C IEWFHY CV +T +PKG WFCP C
Sbjct:  335 PESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQC 398

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing1 (inhibitor of growth family, member 1 [Source:MGI Symbol;Acc:MGI:1349481])

HSP 1 Score: 79.337 bits (194), Expect = 1.298e-16
Identity = 28/49 (57.14%), Postives = 37/49 (75.51%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
             YC+CN+ SYG+MI CD+D+C IEWFH+ CV +   PKG W+CP C+ E
Sbjct:  117 TYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGE 165

[Close]

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
             YC+CN+ SYG+MI CD+D+C IEWFH+ CV +   PKG W+CP C+ E
Sbjct:  117 TYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGE 165

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|P38806|YNG2_YEAST (Chromatin modification-related protein YNG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YNG2 PE=1 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.315e-17
Identity = 36/80 (45.00%), Postives = 51/80 (63.75%), Query Frame = 2

Query:  824 KRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            K+++ +  F  +R  + Q N S   + ED  +YC C + S+G+M+ACD   CK EWFHY CV++   PKG W+CP CKIE
Sbjct:  193 KKIARTKEFKNSRNGKGQ-NGSPENEEEDKTLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIE 271

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q6CXN0|YNG2_KLULA (Chromatin modification-related protein YNG2 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=YNG2 PE=3 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 9.190e-17
Identity = 29/55 (52.73%), Postives = 41/55 (74.55%), Query Frame = 2

Query:  899 DHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            + +D ++YC C + SYG+M+ACD   CK EWFHY CV++T  PKG W+CP C++E
Sbjct:  228 EEDDKQLYCFCQRVSYGEMVACDGPNCKYEWFHYSCVNLTEPPKGQWYCPECRLE 282

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q6FSB1|YNG2_CANGA (Chromatin modification-related protein YNG2 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) OX=284593 GN=YNG2 PE=3 SV=1)

HSP 1 Score: 83.9593 bits (206), Expect = 1.217e-16
Identity = 30/55 (54.55%), Postives = 40/55 (72.73%), Query Frame = 2

Query:  899 DHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            + ED  +YC C + S+G+M+ACD   CK EWFHY+CV++T  PKG W+CP CK E
Sbjct:  210 EKEDQNLYCFCQRVSFGEMVACDGPNCKYEWFHYECVNLTEPPKGTWYCPDCKQE 264

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q9D8Y8|ING5_MOUSE (Inhibitor of growth protein 5 OS=Mus musculus OX=10090 GN=Ing5 PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 3.522e-16
Identity = 31/50 (62.00%), Postives = 38/50 (76.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C  EK
Sbjct:  187 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEK 236

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q8WYH8|ING5_HUMAN (Inhibitor of growth protein 5 OS=Homo sapiens OX=9606 GN=ING5 PE=1 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 5.050e-16
Identity = 31/50 (62.00%), Postives = 38/50 (76.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C  EK
Sbjct:  187 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEK 236

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A0V0XTK4 (Inhibitor of growth protein OS=Trichinella pseudospiralis OX=6337 GN=YNG2 PE=3 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 3.017e-17
Identity = 38/82 (46.34%), Postives = 53/82 (64.63%), Query Frame = 2

Query:  812 SNKRKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            S+ R + S   S ++    +   N +   D +D  +YC CN+PSYG M+ACDS  CK EWFHY+CV +T +PKG+WFCP C+
Sbjct:  288 SHSRSKASKKASTVHTEAAQGDAN-AEAGDVDDQSIYCYCNQPSYGSMVACDSITCKYEWFHYECVGVTEAPKGNWFCPDCR 368

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A0R3W8A6 (PHD-type domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS6577 PE=4 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 9.888e-17
Identity = 39/81 (48.15%), Postives = 52/81 (64.20%), Query Frame = 2

Query:  821 RKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            R R   ++S + NR+       S   D    ++YC+C K SYGDMIACD+ +C+IEWFH+ CVDI T PKG W+CP C+ E
Sbjct:  249 RPRSRSTSSPLRNRKREVGRTSSTTADVSGERLYCLCKKLSYGDMIACDNPRCEIEWFHFACVDIKTQPKGRWYCPRCRGE 329

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A0R3S8H2 (PHD-type domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS444 PE=4 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 1.162e-16
Identity = 45/110 (40.91%), Postives = 63/110 (57.27%), Query Frame = 2

Query:  740 AVESSIKSKSNICLNSADSKYLSFSNKRKRLSL--SNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            A ES +   S    + + S Y S +  RK  +    +S + NRR R+  +     D    ++YC+C   SYGDMIACD+ +CKIEWFH+ CVD+   PKG W+CP C+ E
Sbjct:  221 ASESRLPPPSPEASDRSSSDYESENESRKHQASRSGSSPVRNRRQRDNGS-----DGTGERIYCLCKSYSYGDMIACDNSRCKIEWFHFACVDVKIQPKGKWYCPKCRGE 325

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A564YJV2 (PHD-type domain-containing protein (Fragment) OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS7097 PE=4 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.226e-16
Identity = 45/110 (40.91%), Postives = 63/110 (57.27%), Query Frame = 2

Query:  740 AVESSIKSKSNICLNSADSKYLSFSNKRKRLSL--SNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            A ES +   S    + + S Y S +  RK  +    +S + NRR R+  +     D    ++YC+C   SYGDMIACD+ +CKIEWFH+ CVD+   PKG W+CP C+ E
Sbjct:  216 ASESRLPPPSPEASDRSSSDYESENESRKHQASRSGSSPVRNRRQRDNGS-----DGTGERIYCLCKSYSYGDMIACDNSRCKIEWFHFACVDVKIQPKGKWYCPKCRGE 320

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A0R3WHJ5 (PHD-type domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS13 PE=4 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.734e-16
Identity = 38/81 (46.91%), Postives = 52/81 (64.20%), Query Frame = 2

Query:  821 RKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            R R   ++S + +R+       S   D    ++YC+C K SYGDMIACD+ +C+IEWFH+ CVDI T PKG W+CP C+ E
Sbjct:  247 RPRSRSTSSPLRSRKREAAGASSTAADVSGERLYCLCKKLSYGDMIACDNPRCEIEWFHFACVDIKTQPKGRWYCPRCRGE 327

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing5b (inhibitor of growth protein 5-like [Source:NCBI gene;Acc:103037104])

HSP 1 Score: 82.0333 bits (201), Expect = 2.513e-17
Identity = 29/49 (59.18%), Postives = 39/49 (79.59%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG+WFCP C ++
Sbjct:  183 TYCLCSQVSYGEMIGCDNADCPIEWFHFACVDLTTKPKGEWFCPRCVLD 231

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing5a (inhibitor of growth family member 5 [Source:NCBI gene;Acc:103024432])

HSP 1 Score: 80.8777 bits (198), Expect = 8.595e-17
Identity = 35/81 (43.21%), Postives = 50/81 (61.73%), Query Frame = 2

Query:  812 SNKRKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            S ++K++  SN F  +  P +  +        +   YC+C++ SYG+MI CD+  C IEWFH+ CVD+TT PKG WFCP C
Sbjct:  154 SPRKKKMKNSNEFSDSLLPVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRC 234

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing3 (inhibitor of growth family member 3 [Source:NCBI gene;Acc:103046788])

HSP 1 Score: 82.0333 bits (201), Expect = 2.892e-16
Identity = 28/45 (62.22%), Postives = 35/45 (77.78%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            YCICN+ SYG+M+ CD+  C IEWFHY CV +T +PKG W+CP C
Sbjct:  362 YCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC 406

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing4 (inhibitor of growth family, member 4 [Source:ZFIN;Acc:ZDB-GENE-050522-47])

HSP 1 Score: 78.1814 bits (191), Expect = 1.756e-15
Identity = 27/50 (54.00%), Postives = 37/50 (74.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+C++ SYG+MI CD+  C IEWFH+ CV +TT P+G W+CP C  E+
Sbjct:  245 TYCLCHQVSYGEMIGCDNTDCSIEWFHFACVGLTTKPRGKWYCPRCSQER 294

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing2 (inhibitor of growth family member 2 [Source:NCBI gene;Acc:103031897])

HSP 1 Score: 77.7962 bits (190), Expect = 1.782e-15
Identity = 26/47 (55.32%), Postives = 36/47 (76.60%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
             YC+C + SYG+MI CD+++C IEWFH+ CV +T  PKG W+CP C+
Sbjct:  213 TYCLCEQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGRWYCPKCR 259

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008794.1 (pep scaffold:Pmarinus_7.0:GL476329:1735629:1740570:1 gene:ENSPMAG00000007965.1 transcript:ENSPMAT00000008794.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.3445 bits (207), Expect = 1.611e-19
Identity = 29/50 (58.00%), Postives = 37/50 (74.00%), Query Frame = 2

Query:  908 DAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            D   YC+CN+ SYGDMI CD++ C IEWFH+ CV ++  PKG WFCP C+
Sbjct:   57 DEPTYCLCNQVSYGDMIGCDNEACAIEWFHFGCVGLSHKPKGKWFCPRCR 106

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000234.1 (pep scaffold:Pmarinus_7.0:GL482739:14:2848:1 gene:ENSPMAG00000000213.1 transcript:ENSPMAT00000000234.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.485 bits (184), Expect = 1.542e-16
Identity = 27/47 (57.45%), Postives = 35/47 (74.47%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKI 1060
            YCICN+ SYG+M+ CD+  C IEWFHY CV +  +PKG W+CP C +
Sbjct:   86 YCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLKEAPKGKWYCPQCTV 132

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Match: YNG2 (Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; relocalizes to the cytosol in response to hypoxia; similar to human tumor suppressor ING1 and its isoforms ING4 and ING5 [Source:SGD;Acc:S000001132])

HSP 1 Score: 87.0409 bits (214), Expect = 1.893e-19
Identity = 36/80 (45.00%), Postives = 51/80 (63.75%), Query Frame = 2

Query:  824 KRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            K+++ +  F  +R  + Q N S   + ED  +YC C + S+G+M+ACD   CK EWFHY CV++   PKG W+CP CKIE
Sbjct:  193 KKIARTKEFKNSRNGKGQ-NGSPENEEEDKTLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIE 271

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Match: PHO23 (Component of the Rpd3L histone deacetylase complex; involved in transcriptional regulation of PHO5; affects termination of snoRNAs and cryptic unstable transcripts (CUTs); C-terminus shares significant sequence identity with the human candidate tumor suppressor p33-ING1 and its isoform ING3 [Source:SGD;Acc:S000005041])

HSP 1 Score: 70.4774 bits (171), Expect = 1.072e-13
Identity = 23/47 (48.94%), Postives = 33/47 (70.21%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            +YC CN+ +YG+M+ CD   C++EWFH  C+ + T PKG W+C  CK
Sbjct:  281 LYCYCNQVAYGEMVGCDGADCELEWFHLPCIGLETLPKGKWYCDDCK 327

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Match: YNG1 (Subunit of the NuA3 histone acetyltransferase complex; this complex acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3; shares significant sequence identity with the human candidate tumor suppressor p33-ING1 in C-terminal region [Source:SGD;Acc:S000005590])

HSP 1 Score: 67.781 bits (164), Expect = 1.911e-13
Identity = 24/44 (54.55%), Postives = 30/44 (68.18%), Query Frame = 2

Query:  914 KVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFC 1045
            +VYC C   SYG M+ACD+  C  EWFHY CV +  +PKG W+C
Sbjct:  155 EVYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYC 198

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO40594 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6P9])

HSP 1 Score: 73.9442 bits (180), Expect = 1.400e-16
Identity = 27/48 (56.25%), Postives = 37/48 (77.08%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            YC+CN+ SYG+M+ CD++ C IEWFHY CV +T +PKG W+CP C  +
Sbjct:   13 YCLCNQVSYGEMVGCDNNDCPIEWFHYGCVGLTDAPKGKWYCPQCSTQ 60

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO43857 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXJ4])

HSP 1 Score: 78.1814 bits (191), Expect = 3.100e-16
Identity = 26/50 (52.00%), Postives = 40/50 (80.00%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEK 1066
             YC+CN+ S+G+MI CD+++C+IEWFH++CV ++  PKG W+CP C  E+
Sbjct:  204 TYCLCNQVSFGEMIGCDNEECQIEWFHFQCVGLSHKPKGKWYCPRCMQER 253

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO35780 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKJ2])

HSP 1 Score: 62.3882 bits (150), Expect = 8.082e-13
Identity = 24/46 (52.17%), Postives = 31/46 (67.39%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            YC+C +   G+MIACDS  C I WFH  C+ +TT+P G+W C V K
Sbjct:    1 YCLCGQGESGEMIACDSPSCPIVWFHMDCIGMTTAPDGEWLCRVSK 46

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO37532 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFP0])

HSP 1 Score: 63.5438 bits (153), Expect = 9.322e-12
Identity = 22/38 (57.89%), Postives = 28/38 (73.68%), Query Frame = 2

Query:  941 SYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            SYG+MI CD+ +C IEWFH+ CV +   PKG W+CP C
Sbjct:  136 SYGEMIGCDNMECPIEWFHFPCVGLVAKPKGKWYCPKC 173

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO33191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSY4])

HSP 1 Score: 53.9138 bits (128), Expect = 1.129e-9
Identity = 22/48 (45.83%), Postives = 32/48 (66.67%), Query Frame = 2

Query:  920 YCICNKPS-YGD-MIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            +C+C +P   GD MI CD+  CK +WFH+ C+ +  +PKG W+C  CK
Sbjct:    1 FCVCQQPECEGDEMIGCDNPSCKYKWFHFTCIKLKRAPKGGWYCKFCK 48

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing3 (inhibitor of growth family member 3 [Source:NCBI gene;Acc:101168096])

HSP 1 Score: 81.6481 bits (200), Expect = 3.023e-16
Identity = 31/64 (48.44%), Postives = 42/64 (65.62%), Query Frame = 2

Query:  866 PRNQPNKSHFWDHE-DAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
            P  + N    W ++ +   YCICN+ SYG+M+ CD+  C IEWFHY CV +T +PKG W+CP C
Sbjct:  341 PEAEANSQVDWTYDPNEPRYCICNQVSYGEMVGCDNTDCPIEWFHYGCVGLTEAPKGKWYCPQC 404

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing5a (inhibitor of growth family member 5 [Source:NCBI gene;Acc:101171565])

HSP 1 Score: 79.337 bits (194), Expect = 3.067e-16
Identity = 28/46 (60.87%), Postives = 35/46 (76.09%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
             YC+C++ SYG+MI CD+  C IEWFH+ CVD+ T PKG WFCP C
Sbjct:  189 TYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLATKPKGKWFCPRC 234

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing1 (inhibitor of growth family member 1 [Source:NCBI gene;Acc:101155310])

HSP 1 Score: 78.9518 bits (193), Expect = 8.424e-16
Identity = 28/52 (53.85%), Postives = 37/52 (71.15%), Query Frame = 2

Query:  908 DAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 1063
            D   YC+C + SYG+MI CD+D+C IEWFH+ CV +   PKG W+CP C+ E
Sbjct:  233 DEPTYCLCEQVSYGEMIGCDNDECPIEWFHFSCVGLHHKPKGKWYCPKCRGE 284

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing4 (inhibitor of growth family member 4 [Source:NCBI gene;Acc:105355951])

HSP 1 Score: 77.411 bits (189), Expect = 1.223e-15
Identity = 26/46 (56.52%), Postives = 36/46 (78.26%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVC 1054
             YC+C++ SYG+MI CD+ +C IEWFH+ CV +TT P+G W+CP C
Sbjct:  197 TYCLCHQVSYGEMIGCDNTECSIEWFHFACVGLTTKPRGKWYCPRC 242

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing2 (inhibitor of growth family member 2 [Source:NCBI gene;Acc:101160358])

HSP 1 Score: 77.7962 bits (190), Expect = 1.590e-15
Identity = 26/47 (55.32%), Postives = 36/47 (76.60%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
             YC+C + SYG+MI CD+++C IEWFH+ CV +T  PKG W+CP C+
Sbjct:  216 TYCLCEQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGKWYCPKCR 262

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000015211.1 (SMESG000015211.1)

HSP 1 Score: 546.969 bits (1408), Expect = 0.000e+0
Identity = 304/306 (99.35%), Postives = 305/306 (99.67%), Query Frame = 2

Query:  152 MANNCIQLLNDLYCSLSNKMSCFVSAHINFNINFDHKLKEINSLLINDQLENINLIXXXXXXXXXXXXXXXXXXCTEEMNTVCSLQNQVFQDCNNDVNIIEMERSPVSLFVNDNLSCEVNQTKLKFREISLPRTKLCDVKNSIVVNKHDHCTKEKFPLYRSKGGSFLHKKLNFNAKQTXXXXXXXXXXXXQNLFKNAVESSIKSKSNICLNSADSKYLSFSNKRKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEKY 1069
            MANNCIQLLNDLYCSLSNKMSCFVSAHINFNINFDHKLKEINSLLINDQLENINLIKLGSELSELHSLLDLKLKCTEEMNTVCS+QNQVFQDCNNDVNIIEMERSP SLFVNDNLSCEVNQTKLKFREISLPRTKLCDVKNSIVVNKHDHCTKEKFPLYRSKGGSFLHKKLNFNAKQTKHKSKKFISFKKQNLFKNAVESSIKSKSNICLNSADSKYLSFSNKRKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEKY
Sbjct:    1 MANNCIQLLNDLYCSLSNKMSCFVSAHINFNINFDHKLKEINSLLINDQLENINLIKLGSELSELHSLLDLKLKCTEEMNTVCSMQNQVFQDCNNDVNIIEMERSPGSLFVNDNLSCEVNQTKLKFREISLPRTKLCDVKNSIVVNKHDHCTKEKFPLYRSKGGSFLHKKLNFNAKQTKHKSKKFISFKKQNLFKNAVESSIKSKSNICLNSADSKYLSFSNKRKRLSLSNSFIYNRRPRNQPNKSHFWDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIEKY 306

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000073543.1 (SMESG000073543.1)

HSP 1 Score: 75.485 bits (184), Expect = 1.885e-15
Identity = 27/47 (57.45%), Postives = 38/47 (80.85%), Query Frame = 2

Query:  917 VYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            VYC+C++ S+G+M+ACD+  C IEWFH+ CV +T+ PKG WFCP C+
Sbjct:  156 VYCLCHQVSFGEMVACDNKNCSIEWFHFSCVSLTSKPKGMWFCPNCR 202

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000025474.1 (SMESG000025474.1)

HSP 1 Score: 75.8702 bits (185), Expect = 4.263e-15
Identity = 28/46 (60.87%), Postives = 34/46 (73.91%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            YC C K +YG MIACD+  CKIEWFH KCV++   P G+WFCP C+
Sbjct:  212 YCYCKKGAYGKMIACDNSGCKIEWFHNKCVNVIDVPNGEWFCPECR 257

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000025459.1 (SMESG000025459.1)

HSP 1 Score: 75.0998 bits (183), Expect = 6.689e-15
Identity = 28/46 (60.87%), Postives = 34/46 (73.91%), Query Frame = 2

Query:  920 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            YC C K +YG MIACD+  CKIEWFH KCV++   P G+WFCP C+
Sbjct:  212 YCYCKKGAYGKMIACDNSGCKIEWFHNKCVNVIDVPNGEWFCPECR 257

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000056794.1 (SMESG000056794.1)

HSP 1 Score: 76.2554 bits (186), Expect = 1.316e-14
Identity = 30/54 (55.56%), Postives = 35/54 (64.81%), Query Frame = 2

Query:  896 WDHEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCK 1057
            +D  +   YC CN  SYGDMIACD   C  EWFHY CV++  +PKG WFC  CK
Sbjct:  353 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCK 406

The following BLAST results are available for this feature:

BLAST of Inhibitor of growth protein vs. Ensembl Human
BLAST of Inhibitor of growth protein vs. Ensembl Celegans
BLAST of Inhibitor of growth protein vs. Ensembl Fly
BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
BLAST of Inhibitor of growth protein vs. Ensembl Mouse
BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
BLAST of Inhibitor of growth protein vs. TrEMBL
BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
BLAST of Inhibitor of growth protein vs. Ensembl Yeast
BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
BLAST of Inhibitor of growth protein vs. Ensembl Medaka
BLAST of Inhibitor of growth protein vs. Planmine SMEST

BLAST of Inhibitor of growth protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ING5	1.052e-16	62.00	inhibitor of growth family member 5 [Source:HGNC S...	[more]
ING1	1.832e-16	57.14	inhibitor of growth family member 1 [Source:HGNC S...	[more]
ING1	2.725e-16	57.14	inhibitor of growth family member 1 [Source:HGNC S...	[more]
ING1	4.837e-16	57.14	inhibitor of growth family member 1 [Source:HGNC S...	[more]
ING3	4.996e-16	62.22	inhibitor of growth family member 3 [Source:HGNC S...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing-3	2.992e-14	46.30	Inhibitor of growth protein [Source:UniProtKB/TrE...	[more]
lsy-13	1.722e-8	42.55	pep chromosome:WBcel235:IV:16864655:16865476:1 gen...	[more]
lsy-13	2.751e-8	32.94	pep chromosome:WBcel235:IV:16863866:16865479:1 gen...	[more]
lsy-13	2.751e-8	32.94	pep chromosome:WBcel235:IV:16862396:16865476:1 gen...	[more]
Y43H11AL.1	4.529e-7	33.96	pep chromosome:WBcel235:II:222704:223799:-1 gene:W...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ing3	1.635e-16	66.67	gene:FBgn0030945 transcript:FBtr0074614	[more]
CG7379	6.462e-16	54.72	gene:FBgn0038546 transcript:FBtr0083529	[more]
Ing5	8.589e-16	60.87	gene:FBgn0032516 transcript:FBtr0080525	[more]
Ing5	9.656e-16	60.87	gene:FBgn0032516 transcript:FBtr0080526	[more]
MESR4	3.826e-11	50.94	gene:FBgn0034240 transcript:FBtr0340220	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing5a	2.244e-16	63.04	inhibitor of growth family, member 5a [Source:ZFIN...	[more]
ing5a	2.244e-16	63.04	inhibitor of growth family, member 5a [Source:ZFIN...	[more]
ing3	3.401e-16	62.22	inhibitor of growth family, member 3 [Source:ZFIN;...	[more]
ing4	6.944e-16	54.00	inhibitor of growth family, member 4 [Source:ZFIN;...	[more]
ing1	8.516e-16	57.45	inhibitor of growth family, member 1 [Source:ZFIN;...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lman1l	8.944e-17	60.00	lectin, mannose-binding, 1 like [Source:Xenbase;Ac...	[more]
atp2b2	2.500e-16	59.57	ATPase, Ca++ transporting, plasma membrane 2 [Sour...	[more]
tmem192	1.137e-15	60.00	transmembrane protein 192 [Source:Xenbase;Acc:XB-G...	[more]
ccnf	1.399e-15	55.10	cyclin F [Source:Xenbase;Acc:XB-GENE-963729]	[more]
ING4	3.407e-15	41.57	inhibitor of growth family member 4 [Source:NCBI g...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ing5	4.130e-17	62.00	inhibitor of growth family, member 5 [Source:MGI S...	[more]
Ing5	5.035e-17	62.00	inhibitor of growth family, member 5 [Source:MGI S...	[more]
Ing3	1.296e-16	50.00	inhibitor of growth family, member 3 [Source:MGI S...	[more]
Ing1	1.298e-16	57.14	inhibitor of growth family, member 1 [Source:MGI S...	[more]
Ing1	1.298e-16	57.14	inhibitor of growth family, member 1 [Source:MGI S...	[more]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P38806\|YNG2_YEAST	1.315e-17	45.00	Chromatin modification-related protein YNG2 OS=Sac...	[more]
sp\|Q6CXN0\|YNG2_KLULA	9.190e-17	52.73	Chromatin modification-related protein YNG2 OS=Klu...	[more]
sp\|Q6FSB1\|YNG2_CANGA	1.217e-16	54.55	Chromatin modification-related protein YNG2 OS=Can...	[more]
sp\|Q9D8Y8\|ING5_MOUSE	3.522e-16	62.00	Inhibitor of growth protein 5 OS=Mus musculus OX=1...	[more]
sp\|Q8WYH8\|ING5_HUMAN	5.050e-16	62.00	Inhibitor of growth protein 5 OS=Homo sapiens OX=9...	[more]

BLAST of Inhibitor of growth protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0V0XTK4	3.017e-17	46.34	Inhibitor of growth protein OS=Trichinella pseudos...	[more]
A0A0R3W8A6	9.888e-17	48.15	PHD-type domain-containing protein OS=Taenia asiat...	[more]
A0A0R3S8H2	1.162e-16	40.91	PHD-type domain-containing protein OS=Hymenolepis ...	[more]
A0A564YJV2	1.226e-16	40.91	PHD-type domain-containing protein (Fragment) OS=H...	[more]
A0A0R3WHJ5	1.734e-16	46.91	PHD-type domain-containing protein OS=Hydatigena t...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing5b	2.513e-17	59.18	inhibitor of growth protein 5-like [Source:NCBI ge...	[more]
ing5a	8.595e-17	43.21	inhibitor of growth family member 5 [Source:NCBI g...	[more]
ing3	2.892e-16	62.22	inhibitor of growth family member 3 [Source:NCBI g...	[more]
ing4	1.756e-15	54.00	inhibitor of growth family, member 4 [Source:ZFIN;...	[more]
ing2	1.782e-15	55.32	inhibitor of growth family member 2 [Source:NCBI g...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000008794.1	1.611e-19	58.00	pep scaffold:Pmarinus_7.0:GL476329:1735629:1740570...	[more]
ENSPMAT00000000234.1	1.542e-16	57.45	pep scaffold:Pmarinus_7.0:GL482739:14:2848:1 gene:...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
YNG2	1.893e-19	45.00	Subunit of NuA4, an essential histone acetyltransf...	[more]
PHO23	1.072e-13	48.94	Component of the Rpd3L histone deacetylase complex...	[more]
YNG1	1.911e-13	54.55	Subunit of the NuA3 histone acetyltransferase comp...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40594	1.400e-16	56.25	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43857	3.100e-16	52.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35780	8.082e-13	52.17	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37532	9.322e-12	57.89	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33191	1.129e-9	45.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing3	3.023e-16	48.44	inhibitor of growth family member 3 [Source:NCBI g...	[more]
ing5a	3.067e-16	60.87	inhibitor of growth family member 5 [Source:NCBI g...	[more]
ing1	8.424e-16	53.85	inhibitor of growth family member 1 [Source:NCBI g...	[more]
ing4	1.223e-15	56.52	inhibitor of growth family member 4 [Source:NCBI g...	[more]
ing2	1.590e-15	55.32	inhibitor of growth family member 2 [Source:NCBI g...	[more]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000015211.1	0.000e+0	99.35	SMESG000015211.1	[more]
SMESG000073543.1	1.885e-15	57.45	SMESG000073543.1	[more]
SMESG000025474.1	4.263e-15	60.87	SMESG000025474.1	[more]
SMESG000025459.1	6.689e-15	60.87	SMESG000025459.1	[more]
SMESG000056794.1	1.316e-14	55.56	SMESG000056794.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30029420 ID=SMED30029420|Name=Inhibitor of growth protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1666bp
TGTATTTTGTAATTATGTAATAATATTGAGAAATAATTCATTGGAATCAT
AATAATTTGATTCGAATATTTATTAGTGAAATTTAAAAAAAAGAATTACT
GATATATTTATCTTTATTCCGGATATTTTAAGTAATTTAGATCATTGTTT
CATGGCTAATAATTGTATTCAATTGTTAAATGATCTTTATTGTTCATTGT
CCAATAAAATGAGTTGCTTTGTTTCAGCACACATTAATTTTAATATTAAT
TTTGATCACAAGCTGAAAGAAATTAATTCTCTCCTTATTAATGATCAATT
GGAGAATATAAATTTAATCAAATTAGGCAGTGAATTAAGCGAACTTCATT
CACTTTTAGATTTAAAGCTAAAGTGTACTGAAGAAATGAATACAGTTTGC
TCTCTGCAAAATCAAGTATTTCAAGACTGCAATAATGATGTGAATATTAT
TGAAATGGAAAGATCTCCTGTATCTTTATTTGTAAATGACAATCTCAGTT
GTGAAGTAAATCAAACGAAATTGAAATTTCGTGAAATATCTCTTCCTAGA
ACTAAATTGTGTGATGTTAAAAATTCTATTGTCGTTAACAAACACGATCA
CTGCACTAAAGAAAAGTTTCCTCTTTATAGAAGTAAAGGTGGCTCATTTT
TGCATAAAAAATTAAACTTCAATGCTAAACAAACAAAACATAAATCAAAG
AAATTTATATCTTTTAAAAAACAGAATCTATTTAAAAATGCAGTGGAATC
TAGTATTAAATCTAAATCAAATATTTGCCTAAACTCGGCTGATTCAAAAT
ATTTAAGTTTCAGCAATAAAAGGAAGCGCTTGTCATTATCAAATAGTTTT
ATTTACAACAGACGTCCTAGAAATCAGCCAAATAAATCCCATTTCTGGGA
TCATGAAGACGCCAAAGTTTATTGTATTTGTAATAAACCCTCATATGGAG
ATATGATCGCGTGTGACAGTGACAAATGTAAAATAGAATGGTTTCATTAT
AAATGCGTTGATATCACCACCAGTCCCAAAGGGGATTGGTTTTGTCCAGT
ATGTAAAATAGAAAAGTATTAAGTGGATTTTAATTTTCGTATTTAGTAAT
TTTTGGTTTTTGTTCAAAAATATATTTAATTTATTCATTTTAATGCTTTG
ATGTAAATTTGGTATGTAAATAAAGTTTGGTTTAATGTTTATGTTAAATC
ATTTAAATTAGTTTTATCCCATTAAAGGAATGTTTTCAGTCATTTTCACT
TGAGAGAATTTTCTAATGAGAAAAAAAATTCATAACAAAGCACAAATTAC
GGATTGAATAGCCCAAAATTAAAGTTTATAAAGATTGTAGCTGACACTTA
AAATTAGAAAACTTTCAATTGTTGAATTTGTGAGGTATAAGTGTATTTAC
TTTTAAGGGGCACATACGCAAAACTCCAGATTTTGGCACCCTTTCCGGTT
GCAGTTCGTACACTTTTAGACTCCAGTCCAGCTGGCTTACCAAGAACGGA
ATGGATCAGCTCAAACCATCAAAACCAATCGTTCACTTGCGAAGCCCAGA
CGCTCCGAACCAATGAAGCGATGTTTGCAAGCAACTGGAAATCCTCGAAA
TTATCCATAAAAGCCGAAATGGGACATTTTGATAACTCGTGACCTAAACA
ATAAATTCTTGTGTGC

protein sequence of SMED30029420-orf-1

>SMED30029420-orf-1 ID=SMED30029420-orf-1|Name=SMED30029420-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=307bp
MANNCIQLLNDLYCSLSNKMSCFVSAHINFNINFDHKLKEINSLLINDQL
ENINLIKLGSELSELHSLLDLKLKCTEEMNTVCSLQNQVFQDCNNDVNII
EMERSPVSLFVNDNLSCEVNQTKLKFREISLPRTKLCDVKNSIVVNKHDH
CTKEKFPLYRSKGGSFLHKKLNFNAKQTKHKSKKFISFKKQNLFKNAVES
SIKSKSNICLNSADSKYLSFSNKRKRLSLSNSFIYNRRPRNQPNKSHFWD
HEDAKVYCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPV
CKIEKY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0006325	chromatin organization

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR028651	ING_fam
IPR001965	Znf_PHD
IPR013083	Znf_RING/FYVE/PHD
IPR019787	Znf_PHD-finger
IPR019786	Zinc_finger_PHD-type_CS
IPR011011	Znf_FYVE_PHD

Vocabulary: **molecular function**
Term	Definition
GO:0008270	zinc ion binding
GO:0005515	protein binding
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0046872	metal ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001965	Zinc finger, PHD-type	SMART	SM00249	PHD_3	coord: 257..302 e-value: 7.7E-12 score: 55.3
IPR019787	Zinc finger, PHD-finger	PFAM	PF00628	PHD	coord: 257..303 e-value: 4.0E-7 score: 29.8
IPR019787	Zinc finger, PHD-finger	PROSITE	PS50016	ZF_PHD_2	coord: 255..304 score: 9.606
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 248..305 e-value: 4.9E-24 score: 86.0
IPR028651	ING family	PANTHER	PTHR10333	INHIBITOR OF GROWTH PROTEIN	coord: 193..302
None	No IPR available	PANTHER	PTHR10333:SF96	INHIBITOR OF GROWTH PROTEIN 3	coord: 193..302
None	No IPR available	CDD	cd15505	PHD_ING	coord: 257..301 e-value: 1.14984E-23 score: 89.2799
IPR019786	Zinc finger, PHD-type, conserved site	PROSITE	PS01359	ZF_PHD_1	coord: 258..301
IPR011011	Zinc finger, FYVE/PHD-type	SUPERFAMILY	SSF57903	FYVE/PHD zinc finger	coord: 242..304