Low density lipoprotein receptor class A cysteine rich

Overview
NameLow density lipoprotein receptor class A cysteine rich
Smed IDSMED30029360
Length (bp)1244
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Low density lipoprotein receptor class A cysteine rich (SMED30029360) t-SNE clustered cells

Violin plots show distribution of expression levels for Low density lipoprotein receptor class A cysteine rich (SMED30029360) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Low density lipoprotein receptor class A cysteine rich (SMED30029360) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Low density lipoprotein receptor class A cysteine rich (SMED30029360) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029360

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30029360SMESG000073751.1 dd_Smed_v4_2114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30029360SMESG000073751.1 dd_Smed_v4_2114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30029360SMESG000073751.1 dd_Smed_v4_2114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30029360SMESG000073751.1 dd_Smed_v4_2114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30029360SMESG000073751.1 dd_Smed_v4_2114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30029360SMESG000073751.1 dd_Smed_v4_2114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30029360SMESG000073751.1 dd_Smed_v4_2114_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Low density lipoprotein receptor class A cysteine rich vs. TrEMBL
Match: A0A4S2LLI5 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006348 PE=4 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 4.956e-46
Identity = 77/200 (38.50%), Postives = 127/200 (63.50%), Query Frame = 1 
Query:  211 VSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSXXXXXXXXXXXXSVCPSIKLEVYQTTRYEL--QMVNEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPL 804
            V T DCF +P NP+ + G  +++S   G+  CY+GP ++  Y S+  +TL L +  S CP++ +  Y + R EL       +++  V+P +PK +F +DCTNY   +  +V++  PG RI + ++P +    + ++ + ++S++IG S++CP   +RCW+   +CI ESL CD +DNC+D+SDEN+Y CTGRI  IP+PL
Sbjct:   28 VDTQDCFGLPQNPITLAGAFVANSRLPGRTTCYFGPSESGQYLSMRFSTLLLPRKASSCPTLTINEYSSVREELIDDTDPNLRVPMVIPADPKQLFRSDCTNYEKMLEQVVRTSAPGLRIEMIFEPMNADLTDVSYTLIITSFLIGPSFNCPSGTFRCWSDRSRCIPESLTCDGIDNCFDDSDENNYLCTGRINGIPIPL 227
[Close]
BLAST of Low density lipoprotein receptor class A cysteine rich vs. TrEMBL
Match: A0A4S2LLI2 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006348 PE=4 SV=1)

HSP 1 Score: 168.703 bits (426), Expect = 7.788e-46
Identity = 77/200 (38.50%), Postives = 127/200 (63.50%), Query Frame = 1 
Query:  211 VSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSXXXXXXXXXXXXSVCPSIKLEVYQTTRYEL--QMVNEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPL 804
            V T DCF +P NP+ + G  +++S   G+  CY+GP ++  Y S+  +TL L +  S CP++ +  Y + R EL       +++  V+P +PK +F +DCTNY   +  +V++  PG RI + ++P +    + ++ + ++S++IG S++CP   +RCW+   +CI ESL CD +DNC+D+SDEN+Y CTGRI  IP+PL
Sbjct:   28 VDTQDCFGLPQNPITLAGAFVANSRLPGRTTCYFGPSESGQYLSMRFSTLLLPRKASSCPTLTINEYSSVREELIDDTDPNLRVPMVIPADPKQLFRSDCTNYEKMLEQVVRTSAPGLRIEMIFEPMNADLTDVSYTLIITSFLIGPSFNCPSGTFRCWSDRSRCIPESLTCDGIDNCFDDSDENNYLCTGRINGIPIPL 227
[Close]
BLAST of Low density lipoprotein receptor class A cysteine rich vs. TrEMBL
Match: A0A4S2LLD9 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006348 PE=4 SV=1)

HSP 1 Score: 169.474 bits (428), Expect = 8.520e-46
Identity = 77/200 (38.50%), Postives = 127/200 (63.50%), Query Frame = 1 
Query:  211 VSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSXXXXXXXXXXXXSVCPSIKLEVYQTTRYEL--QMVNEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPL 804
            V T DCF +P NP+ + G  +++S   G+  CY+GP ++  Y S+  +TL L +  S CP++ +  Y + R EL       +++  V+P +PK +F +DCTNY   +  +V++  PG RI + ++P +    + ++ + ++S++IG S++CP   +RCW+   +CI ESL CD +DNC+D+SDEN+Y CTGRI  IP+PL
Sbjct:   28 VDTQDCFGLPQNPITLAGAFVANSRLPGRTTCYFGPSESGQYLSMRFSTLLLPRKASSCPTLTINEYSSVREELIDDTDPNLRVPMVIPADPKQLFRSDCTNYEKMLEQVVRTSAPGLRIEMIFEPMNADLTDVSYTLIITSFLIGPSFNCPSGTFRCWSDRSRCIPESLTCDGIDNCFDDSDENNYLCTGRINGIPIPL 227
[Close]
BLAST of Low density lipoprotein receptor class A cysteine rich vs. TrEMBL
Match: G7YQR4 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CLF_107535 PE=4 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 1.287e-45
Identity = 79/220 (35.91%), Postives = 135/220 (61.36%), Query Frame = 1 
Query:  151 FIFSCLIFYWIFSVNALTEIVSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSXXXXXXXXXXXXSVCPSIKLEVYQTTRYEL--QMVNEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPL 804
             +FS L  +W+         V T DCF +P NP+ + G  +++S   G+ +CY+ P ++  Y S+  ++L+L +  S CP++ +  Y + R EL       +++  V+P +PK +F +DCTNY   +  +V++  PG RI + ++P +    + ++ + ++S++IG S++CP   +RCW+   +CI ESL CD +DNC+D+SDEN+Y CTGRI  IP+PL
Sbjct:   26 LVFSKLFNFWL---------VDTQDCFGLPQNPITLAGAFVANSRLPGRTICYFAPSESGQYLSMRFSSLSLPKKGSSCPTLTINEYSSVREELIDDTDPNLRVPMVIPADPKQLFRSDCTNYEKMLEQVVRTSAPGLRIEMIFEPMNSDFTDVSYTLIITSFLIGPSFNCPSGTFRCWSDRSRCIPESLTCDGIDNCFDDSDENNYLCTGRINGIPIPL 236
[Close]
BLAST of Low density lipoprotein receptor class A cysteine rich vs. TrEMBL
Match: A0A5J4NRN5 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0014622 PE=4 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 1.718e-45
Identity = 81/200 (40.50%), Postives = 128/200 (64.00%), Query Frame = 1 
Query:  211 VSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSXXXXXXXXXXXXSVCPSIKLEVYQTTRYELQMVNE--IQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPL 804
            V+T DCF +P++P+ + G  ++ S   G+ +CY+ P+  + Y S+    L L + +  CP+I L  + + R EL   ++  +++  +VP +PK +F A+CTN    I   V++ +PG R+ + +DP S  A +  F +TL+S++IG S++CP   +RCWN   KCI ESL CD V+NC+D+SDEN+Y CTGRI  IP+PL
Sbjct:   18 VNTQDCFGLPESPITLAGAVVTHSQMAGRTLCYFSPLMPEQYLSLQFTVLTLPRQSWNCPTINLNEFSSVRDELIDGDDPNLRVPMIVPADPKLLFFANCTNAEQMIHTSVRTSSPGLRLEMIFDPLSSDATDVFFSMTLTSFMIGPSFNCPSGTFRCWNDRSKCIPESLTCDGVNNCFDDSDENNYLCTGRINGIPIPL 217
[Close]
BLAST of Low density lipoprotein receptor class A cysteine rich vs. Planmine SMEST
Match: SMESG000073751.1 (SMESG000073751.1)

HSP 1 Score: 465.692 bits (1197), Expect = 1.808e-165
Identity = 266/274 (97.08%), Postives = 267/274 (97.45%), Query Frame = 1 
Query:  142 MKIFIFSCLIFYWIFSVNALTEIVSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSXXXXXXXXXXXXSVCPSIKLEVYQTTRYELQMVNEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPLXXXXXXXXXXXXXXXXXXXXXXXRNRKSKGQHKKLATATSHYDGKLYFYHKYM 963
            MKIFIFSCLIFYWIFSVNALTEIVSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSILINTLNLNQINSVCPSIKLEVYQTTRYELQMVNEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPLFAIIIISAILMLIFIIMVIILIMRNRKSKGQHKKLATATSHYD +      YM
Sbjct:    1 MKIFIFSCLIFYWIFSVNALTEIVSTSDCFSIPDNPLRILGVRISSSSEKGKKVCYYGPIDNQYYFSILINTLNLNQINSVCPSIKLEVYQTTRYELQMVNEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSETAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCYDNSDENDYKCTGRIGDIPMPLFAIIIISAILMLIFIIMVIILIMRNRKSKGQHKKLATATSHYDDETLPPRSYM 274
The following BLAST results are available for this feature:
BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2LLI54.956e-4638.50Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A4S2LLI27.788e-4638.50Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A4S2LLD98.520e-4638.50Uncharacterized protein OS=Opisthorchis felineus O... [more]
G7YQR41.287e-4535.91Uncharacterized protein OS=Clonorchis sinensis OX=... [more]
A0A5J4NRN51.718e-4540.50Uncharacterized protein OS=Paragonimus westermani ... [more]
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Low density lipoprotein receptor class A cysteine rich vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000073751.11.808e-16597.08SMESG000073751.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029360 ID=SMED30029360|Name=Low density lipoprotein receptor class A cysteine rich|organism=Schmidtea mediterranea sexual|type=transcript|length=1244bp
CTTCTTTGAAATAATTTCCTATACTGAAATTCGTGTAACAATTTTTATTA
TAATTAAGATATTTCAAATATATACATTTTGCCTAACATATTAAATATTA
TTTTCTTATCTAATTTTTAAAGAATTTCGATAAGATTGACTATGAAAATC
TTTATTTTTTCATGCTTAATTTTTTATTGGATTTTTTCTGTTAATGCTCT
TACGGAAATAGTGTCAACATCCGATTGTTTTAGTATTCCAGACAATCCTT
TACGCATTCTTGGTGTACGCATTTCATCATCAAGTGAAAAAGGGAAAAAA
GTTTGTTACTATGGACCAATAGACAATCAATATTATTTTTCTATTTTAAT
AAATACATTAAATTTAAATCAAATTAATAGTGTTTGTCCTTCAATTAAAC
TTGAAGTTTATCAAACAACTAGATATGAATTACAAATGGTCAATGAAATT
CAATTACAATGGGTTGTACCAGAAAATCCAAAAACAATTTTTACAGCCGA
TTGCACTAATTACGCTAGCAAAATTGGTAATATTGTGCAATCTATGACAC
CTGGAGATCGAATAATGTTAACATATGATCCCGGCAGTGAAACAGCTCCA
AATAATGCTTTTTTTATAACATTGTCGTCATATGTAATTGGTCAATCATA
TAGCTGTCCTGATGTTAAATATCGTTGCTGGAATAGTAATTACAAATGCA
TTGATGAATCTCTATTATGTGACAACGTTGATAATTGCTACGATAATTCC
GATGAAAATGACTATAAATGTACTGGACGTATTGGTGATATACCAATGCC
ACTGTTCGCAATTATTATTATTTCAGCCATTCTAATGCTTATATTTATTA
TAATGGTAATTATTCTAATAATGCGTAATCGGAAATCAAAAGGCCAACAT
AAGAAACTAGCTACGGCAACTAGCCATTACGATGGTAAGTTATATTTCTA
TCATAAATACATGTTTGCATGAAATTAAAATTGAAAATTAAACAAATCAT
ACATTATTTTTTTCAAACATTAAACGCATTTCAATGCAGTCTTTTATAAA
ATGTACTCATCATATTTAAAGACTTACTAAATATCATTGCTTTAAGTTCC
TTCTTATTGGCATCATAATGCTAAATATTCTAAAATAAACAGGATATTCA
TTTATTGAAGAAATAATATTTTGATCTAAATGTAAGTCAACTTTATTTTC
GATTATATCAATTTTATATTTGAACCTATTGAGAGGTTCTTGCT
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protein sequence of SMED30029360-orf-1

>SMED30029360-orf-1 ID=SMED30029360-orf-1|Name=SMED30029360-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=277bp
MKIFIFSCLIFYWIFSVNALTEIVSTSDCFSIPDNPLRILGVRISSSSEK
GKKVCYYGPIDNQYYFSILINTLNLNQINSVCPSIKLEVYQTTRYELQMV
NEIQLQWVVPENPKTIFTADCTNYASKIGNIVQSMTPGDRIMLTYDPGSE
TAPNNAFFITLSSYVIGQSYSCPDVKYRCWNSNYKCIDESLLCDNVDNCY
DNSDENDYKCTGRIGDIPMPLFAIIIISAILMLIFIIMVIILIMRNRKSK
GQHKKLATATSHYDGKLYFYHKYMFA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036055LDL_receptor-like_sf
IPR002172LDrepeatLR_classA_rpt
IPR023415LDLR_class-A_CS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002172Low-density lipoprotein (LDL) receptor class A repeatSMARTSM00192LDLa_2coord: 171..210
e-value: 2.4E-5
score: 33.8
IPR002172Low-density lipoprotein (LDL) receptor class A repeatPROSITEPS50068LDLRA_2coord: 171..211
score: 10.812
IPR002172Low-density lipoprotein (LDL) receptor class A repeatCDDcd00112LDLacoord: 172..207
e-value: 5.746E-8
score: 46.0458
IPR036055LDL receptor-like superfamilyGENE3DG3DSA:4.10.400.10coord: 169..212
e-value: 4.2E-7
score: 31.6
IPR036055LDL receptor-like superfamilySUPERFAMILYSSF57424LDL receptor-like modulecoord: 171..211
IPR023415Low-density lipoprotein (LDL) receptor class A, conserved sitePROSITEPS01209LDLRA_1coord: 186..210
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..19
score: 0.905
NoneNo IPR availableTMHMMTMhelixcoord: 221..243