slc8a-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30029327 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 15
Homology
BLAST of slc8a-1 vs. Ensembl Human
Match: SLC8A3 (solute carrier family 8 member A3 [Source:HGNC Symbol;Acc:HGNC:11070]) HSP 1 Score: 833.558 bits (2152), Expect = 0.000e+0 Identity = 474/907 (52.26%), Postives = 623/907 (68.69%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPR---AVTQDGKKVSI-NQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF ITA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG NL LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D ++KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R ++G +I N L L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I+V I+D+ EYE+ E F I LGEP +++ G + V++ K ++ ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA I+ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFISKVFFDPCSYQCLENCGAVLLTVVRKGGD--MSKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAV---LASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMER-------------GISDVTDRKLTMEE--EEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 921
BLAST of slc8a-1 vs. Ensembl Human
Match: SLC8A3 (solute carrier family 8 member A3 [Source:HGNC Symbol;Acc:HGNC:11070]) HSP 1 Score: 830.861 bits (2145), Expect = 0.000e+0 Identity = 475/907 (52.37%), Postives = 622/907 (68.58%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPR---AVTQDGKKVSI-NQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF ITA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG NL LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D ++KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R ++G +I N L L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I+V I+D+ EYE+ E F I LGEP +++ GI + + T E + ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA I+ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFISKVFFDPCSYQCLENCGAVLLTVVRKGGD--MSKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAV---LASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMER-GISALLLSPDVTDRKLTMEEE--------EAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 927
BLAST of slc8a-1 vs. Ensembl Human
Match: SLC8A3 (solute carrier family 8 member A3 [Source:HGNC Symbol;Acc:HGNC:11070]) HSP 1 Score: 829.321 bits (2141), Expect = 0.000e+0 Identity = 474/911 (52.03%), Postives = 621/911 (68.17%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPR---AVTQDGKKVSI-NQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSE----IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF ITA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG NL LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D ++KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R ++G +I N L L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I+V I+D+ EYE+ E F I LGEP +++ +S + D+ ++ E I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA I+ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFISKVFFDPCSYQCLENCGAVLLTVVRKGGD--MSKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAV---LASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMER----------------GISALLLSPDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 924
BLAST of slc8a-1 vs. Ensembl Human
Match: SLC8A1 (solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068]) HSP 1 Score: 820.076 bits (2117), Expect = 0.000e+0 Identity = 467/937 (49.84%), Postives = 620/937 (66.17%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH-----ELHCNHSLEDAH----LDG----DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNN-QKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXX---XXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFN----------HVSE------VKTHSDQ------LVSQSSE---IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N E CKKG++LP+W+P S GDKIARA VYFV+++Y+FLGVSIIADRFM+SIEVITS+E+++ ++K NGE VRIWNETVSNLTLMALGSSAPEILLSVIE+CG NF AGDLGP TIVGSAAFN+FIII CVYV+PDGE R+IKHL VF +TA+WS+FAY WLY+I++ SP V++VWE LLTFFFF + V+ A+VAD ++ K++ +RY + +E GD E+ + + ++H LDG + E + E+ R + +++E++ K+P+ + + L E A +VL++ KSRAFYR+QATR +TG+GN++K+ ++ R + ++ + EN+ KIFF+ G Y +EN GT + + R G D + V++ TEDGTA AG DY T G V+F+ G+ QK I + II + E N+K ++DG + N ++ G P AT+ + DDDHAGIF FEE T V+ES G E+KV R+SGARG V+VPY++ TA GG D+ + LEF ND+ I V +IDD EYEK++ F +E+GEP LV+ K+ + E GF H E V T +D+ L S+ E I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW+EQF+EAITVS + +D D+ EEKLPSC DYVMHFLT+FWKVLFAFVPPT+Y GW F V I++IG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH G F+V G+L FSVT+F IFA + +L RR +GGELGGPR K+ T+ FV LW++Y+ SSLE YCHIKGF
Sbjct: 44 NETGECTGSYYCKKGVILPIWEP-QDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGD---LTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGI-LEANHVSTLACLG----SPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSE-KKALLLNELGGFTITGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSA--GEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 968
BLAST of slc8a-1 vs. Ensembl Human
Match: SLC8A3 (solute carrier family 8 member A3 [Source:HGNC Symbol;Acc:HGNC:11070]) HSP 1 Score: 819.305 bits (2115), Expect = 0.000e+0 Identity = 470/911 (51.59%), Postives = 617/911 (67.73%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPR---AVTQDGKKVSI-NQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSE----IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF ITA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG NL LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D ++KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R ++G +I N L L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I + +IDD YEK++ + IE+ P +V + + D+ ++ E I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA I+ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFISKVFFDPCSYQCLENCGAVLLTVVRKGGD--MSKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAV---LASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIHIKVIDDEAYEKNKNYFIEMMGPRMVD---------------MSFQKALLLSPDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 925
BLAST of slc8a-1 vs. Ensembl Celegans
Match: ncx-2 (Na/Ca eXchangers [Source:UniProtKB/TrEMBL;Acc:H2KYP4]) HSP 1 Score: 805.438 bits (2079), Expect = 0.000e+0 Identity = 444/933 (47.59%), Postives = 624/933 (66.88%), Query Frame = 2
Query: 377 CIVVIEFLSWIQCEPLKNGACESLNDT-SCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKL---GLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFT-------GFNHVSEVKTHSDQ---------LVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPS-----CLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
C + + FL + C + + T +C G+V+P+W+P L+ GD++ R +YF + Y+FLG+SI+ADRFM+SIEVITS ER ++V++ + + VRIWN+TVSNLTLMALGSSAPEILLS+IE+ FEAGDLGP TIVGSAAFNLF+II CV VIP GE+RR KHL VF +TA+WSVFAY+WLYLI+AFFSP I++WE LTF FF LTV TAY+AD K+ KFL RY R + E+ LE+ GD L E+ R ++IE++REIR +NP+I P L++QA+ E+++R PKSRAFYR+QATR L G G+++KK ++++ ++ D L K+ +N KIF DP HYTV+E+VG+F+V+V R G + + + V+Y TEDG+A AG DYI G + F + + + I ++DDD+FE DEHF++ L + R T+DG + ++ + +E+ P ATIM+LDDDHAG+F FE V E+CG +++ R SGARG V++P+R+ TA+ + E + F ++QTEA +++ I+D +YE+ +YF+IEL PI KK S I + F G + SE K + + L EI +MGKPRLG+ + ++ I+ES EF+ +VD ++++ +GT SW+EQF+EA+ VS G++D ++ +D + + C+DYVMH LT+ WK+ FA +PPTDY GGW +F V I +IG LTAV+GDLAS FGC +G+ +AVTAI+FVA+GTS+PDTFASKV+A+ D AD++VGNVTGSNAVNVFLGIG+AWS+AA+YH+ +G+ F V G+LGFSV +FC A+ I ++LRRN++VGGELGGP L+ T ++F LW +Y++LS+LE YC I GF
Sbjct: 6 CWLAVAFLVALAGLADAGSNCSAADATRNCIDGLVIPIWRPFLDLTTGDRVLRGVLYFFVIAYMFLGISIVADRFMSSIEVITSMERTIVVKRPGLDPMAVQVRIWNDTVSNLTLMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAFNLFMIIAICVVVIPKGEIRRQKHLDVFCVTATWSVFAYVWLYLILAFFSPGEIEIWEGALTFIFFPLTVFTAYMADIKLIQNKFLPHRYRRGSHGQMIATEAEEMKM---LENG-TQGDPA--LKAFEEHRQEFIELMREIRKQNPHITPTELQKQAEYEMISRGPKSRAFYRVQATRRLIGGGDIVKK-RIDKEHNKALDALVQAQEKQSRDNTCKIFLDPAHYTVLESVGSFDVVVGRDGGPDGLT---VMVDYFTEDGSANAGSDYIPVKGTLTFYPEDKHQKVTIEVVDDDVFEEDEHFYLRLCNLRVRTKDGIIIDPTRIGGLPVAQLEM--PNTATIMILDDDHAGVFGFEHDHFQVVENCGHLSLQMKRHSGARGKVIIPFRTVEGTASADKHFEMKEGEIVFEDNQTEALVEIGIVDTEQYERSDYFYIELSPPIWAKKMN-DLSRIQERFQRRMERKRGSSVASESKDSNTENGDDEVTTSLTPSQLEIAEMGKPRLGEFTKCQITIRESKEFQGIVDRMIKNANTRIMLGTHSWREQFMEALVVSAGDDDDDEGEDGEDGEEKEPEEPGCMDYVMHVLTVPWKLTFATIPPTDYFGGWATFVVAIFMIGVLTAVVGDLASQFGCWVGLKDAVTAISFVALGTSVPDTFASKVSAVQDKYADNAVGNVTGSNAVNVFLGIGIAWSMAAIYHWNQGTKFLVDPGNLGFSVLIFCTEAVLCIIVLVLRRNKKVGGELGGPIALRWMTAMFFASLWFMYLLLSALEAYCIIPGF 925
BLAST of slc8a-1 vs. Ensembl Celegans
Match: ncx-1 (Na/Ca eXchangers; Sodium-calcium exchanger [Source:UniProtKB/TrEMBL;Acc:G5EF08]) HSP 1 Score: 682.174 bits (1759), Expect = 0.000e+0 Identity = 404/894 (45.19%), Postives = 544/894 (60.85%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLED----AHLDGDKKENLT-------ELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVK--RTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRR-NRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
C G+++P+W+P LS RA VY ++L YLF GVSI+ADRFMASIEVITS+++ V ++K GE TI VR+WNETVSNLTLMALGSSAPEILLSVIEICG+NFEAG+LGP TIVGSAAFNLFIII C+ IP+GE RR++H VF +T WS FAY+WLYLI++ FSP ++VWE +LTF FF LTV +AY AD +R + + S+ + E+ A L GD +NL E R Y+++ +++R ++P+ LE+ A +V+ KSRAFYR+Q TR + GSG++ KK K +L +P + + + FDP HYT +ENVG + VK R E T + V Y T TA A D++ T G + F+ G+ ++ I++ I+D+DI+E DE F + L RA + +L G+ AT++++DDDHAG F F + ESCG +V RS GARG V +PY++ A DY E L+F ++Q++A I + I++D+EYEK E F+IELGEPI + +L IE GKP LG KV+I E EFK+ +D L S +GTSSWK+QF EA T+ P E D E + ++ VMH++ L WK+LFA +PPTDY GW+ F V I +IG LTA IGD+A+ FGCT+G+ ++VTA+T VAMGTSLPDTFAS+ AA+ D AD S+GNVTGSNAVNVFLGIG+AW IAA H ++G+ F V +GSL FSVT+F I ++ +A + RR NR+V GELGGP +I + FV +W++Y++LS+LE YC IKGF
Sbjct: 50 CSPGVIVPVWQPSENLSECKIWFRAIVYLIALAYLFFGVSIVADRFMASIEVITSQQKSVKMKKITGEHFTIMVRVWNETVSNLTLMALGSSAPEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVCIMAIPNGETRRVQHNGVFWVTVVWSTFAYVWLYLILSVFSPGEVEVWEGVLTFVFFPLTVGSAYFADAH---AGQFGQRLISGPLSSFVRRSPRRSPSKKTRENVENGAGLPGDATQNLIGGDADALAFEIHRRHYLDIFKQLRSEHPDAPVVELEKHAMEKVVGEQKKSRAFYRIQTTRKMIGSGDIQKKLKKSNKL--EPMVV-----QKTMATVEFDPPHYTCLENVGDVYLTVKCDRGSVPED---TTVTVHYRTIADTAQAESDFVHTEGTITFEPGQTEQKIKVGIVDNDIYEDDEQFMVRLSQVRAFRSEHFSSVPARL------GLAA----TATVIIVDDDHAGSFGFLSEKFKCTESCGSFVAEVIRSRGARGKVSIPYKTVDGAAKSPQDYEHQEGVLKFADEQSKAEIYIPIVNDDEYEKHEDFYIELGEPIWHR---------------------------ELADDEEGIE--GKPILG-FSRCKVVITEDREFKNFMDRALVTANTSIMVGTSSWKQQFTEAWTLEPEEEDGE----------VTTMEKVMHYIALPWKLLFALIPPTDYFNGWLCFVVAIAMIGLLTAFIGDIAAAFGCTVGLKDSVTALTLVAMGTSLPDTFASRTAAVGDQWADGSIGNVTGSNAVNVFLGIGIAWMIAACVHAYRGTKFLVATGSLAFSVTMFLIGSVVCVALLQYRRFNRKVNGELGGPMGWRIISAGIFVSVWLLYILLSTLEAYCIIKGF 880
BLAST of slc8a-1 vs. Ensembl Celegans
Match: ncx-1 (Na/Ca eXchangers; Sodium-calcium exchanger [Source:UniProtKB/TrEMBL;Acc:G5EF08]) HSP 1 Score: 682.174 bits (1759), Expect = 0.000e+0 Identity = 404/894 (45.19%), Postives = 544/894 (60.85%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLED----AHLDGDKKENLT-------ELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVK--RTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRR-NRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
C G+++P+W+P LS RA VY ++L YLF GVSI+ADRFMASIEVITS+++ V ++K GE TI VR+WNETVSNLTLMALGSSAPEILLSVIEICG+NFEAG+LGP TIVGSAAFNLFIII C+ IP+GE RR++H VF +T WS FAY+WLYLI++ FSP ++VWE +LTF FF LTV +AY AD +R + + S+ + E+ A L GD +NL E R Y+++ +++R ++P+ LE+ A +V+ KSRAFYR+Q TR + GSG++ KK K +L +P + + + FDP HYT +ENVG + VK R E T + V Y T TA A D++ T G + F+ G+ ++ I++ I+D+DI+E DE F + L RA + +L G+ AT++++DDDHAG F F + ESCG +V RS GARG V +PY++ A DY E L+F ++Q++A I + I++D+EYEK E F+IELGEPI + +L IE GKP LG KV+I E EFK+ +D L S +GTSSWK+QF EA T+ P E D E + ++ VMH++ L WK+LFA +PPTDY GW+ F V I +IG LTA IGD+A+ FGCT+G+ ++VTA+T VAMGTSLPDTFAS+ AA+ D AD S+GNVTGSNAVNVFLGIG+AW IAA H ++G+ F V +GSL FSVT+F I ++ +A + RR NR+V GELGGP +I + FV +W++Y++LS+LE YC IKGF
Sbjct: 50 CSPGVIVPVWQPSENLSECKIWFRAIVYLIALAYLFFGVSIVADRFMASIEVITSQQKSVKMKKITGEHFTIMVRVWNETVSNLTLMALGSSAPEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVCIMAIPNGETRRVQHNGVFWVTVVWSTFAYVWLYLILSVFSPGEVEVWEGVLTFVFFPLTVGSAYFADAH---AGQFGQRLISGPLSSFVRRSPRRSPSKKTRENVENGAGLPGDATQNLIGGDADALAFEIHRRHYLDIFKQLRSEHPDAPVVELEKHAMEKVVGEQKKSRAFYRIQTTRKMIGSGDIQKKLKKSNKL--EPMVV-----QKTMATVEFDPPHYTCLENVGDVYLTVKCDRGSVPED---TTVTVHYRTIADTAQAESDFVHTEGTITFEPGQTEQKIKVGIVDNDIYEDDEQFMVRLSQVRAFRSEHFSSVPARL------GLAA----TATVIIVDDDHAGSFGFLSEKFKCTESCGSFVAEVIRSRGARGKVSIPYKTVDGAAKSPQDYEHQEGVLKFADEQSKAEIYIPIVNDDEYEKHEDFYIELGEPIWHR---------------------------ELADDEEGIE--GKPILG-FSRCKVVITEDREFKNFMDRALVTANTSIMVGTSSWKQQFTEAWTLEPEEEDGE----------VTTMEKVMHYIALPWKLLFALIPPTDYFNGWLCFVVAIAMIGLLTAFIGDIAAAFGCTVGLKDSVTALTLVAMGTSLPDTFASRTAAVGDQWADGSIGNVTGSNAVNVFLGIGIAWMIAACVHAYRGTKFLVATGSLAFSVTMFLIGSVVCVALLQYRRFNRKVNGELGGPMGWRIISAGIFVSVWLLYILLSTLEAYCIIKGF 880
BLAST of slc8a-1 vs. Ensembl Celegans
Match: ncx-1 (Na/Ca eXchangers; Sodium-calcium exchanger [Source:UniProtKB/TrEMBL;Acc:G5EF08]) HSP 1 Score: 610.142 bits (1572), Expect = 0.000e+0 Identity = 370/834 (44.36%), Postives = 493/834 (59.11%), Query Frame = 2
Query: 419 PLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLED----AHLDGDKKENLT-------ELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVK--RTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTF 2881
P AC C G+++P+W+P LS RA VY ++L YLF GVSI+ADRFMASIEVITS+++ V ++K GE TI VR+WNETVSNLTLMALGSSAPEILLSVIEICG+NFEAG+LGP TIVGSAAFNLFIII C+ IP+GE RR++H VF +T WS FAY+WLYLI++ FSP ++VWE +LTF FF LTV +AY AD +R + + S+ + E+ A L GD +NL E R Y+++ +++R ++P+ LE+ A +V+ KSRAFYR+Q TR + GSG++ KK K +KL + + FDP HYT +ENVG + VK R E T + V Y T TA A D++ T G + F+ G+ ++ I++ I+D+DI+E DE F + L RA + +L G+ AT++++DDDHAG F F + ESCG +V RS GARG V +PY++ A DY E L+F ++Q++A I + I++D+EYEK E F+IELGEPI + +L IE GKP LG KV+I E EFK+ +D L S +GTSSWK+QF EA T+ P E D E + ++ VMH++ L WK+LFA +PPTDY GW+ F V I +IG LTA IGD+A+ FGCT+G+ ++VTA+T VAMGTSLPDTFAS+ AA+ D AD S+GNVTGSNAVNVFLGIG+AW IAA H ++G+ F
Sbjct: 38 PGPEPACAPAK--PCSPGVIVPVWQPSENLSECKIWFRAIVYLIALAYLFFGVSIVADRFMASIEVITSQQKSVKMKKITGEHFTIMVRVWNETVSNLTLMALGSSAPEILLSVIEICGNNFEAGELGPSTIVGSAAFNLFIIIAVCIMAIPNGETRRVQHNGVFWVTVVWSTFAYVWLYLILSVFSPGEVEVWEGVLTFVFFPLTVGSAYFADAH---AGQFGQRLISGPLSSFVRRSPRRSPSKKTRENVENGAGLPGDATQNLIGGDADALAFEIHRRHYLDIFKQLRSEHPDAPVVELEKHAMEKVVGEQKKSRAFYRIQTTRKMIGSGDIQKKLK-------KSNKLEPMVVQKTMATVEFDPPHYTCLENVGDVYLTVKCDRGSVPED---TTVTVHYRTIADTAQAESDFVHTEGTITFEPGQTEQKIKVGIVDNDIYEDDEQFMVRLSQVRAFRSEHFSSVPARL------GLAA----TATVIIVDDDHAGSFGFLSEKFKCTESCGSFVAEVIRSRGARGKVSIPYKTVDGAAKSPQDYEHQEGVLKFADEQSKAEIYIPIVNDDEYEKHEDFYIELGEPIWHR---------------------------ELADDEEGIE--GKPILG-FSRCKVVITEDREFKNFMDRALVTANTSIMVGTSSWKQQFTEAWTLEPEEEDGE----------VTTMEKVMHYIALPWKLLFALIPPTDYFNGWLCFVVAIAMIGLLTAFIGDIAAAFGCTVGLKDSVTALTLVAMGTSLPDTFASRTAAVGDQWADGSIGNVTGSNAVNVFLGIGIAWMIAACVHAYRGTKF 806
BLAST of slc8a-1 vs. Ensembl Celegans
Match: ncx-2 (Na/Ca eXchangers [Source:UniProtKB/TrEMBL;Acc:H2KYP4]) HSP 1 Score: 503.056 bits (1294), Expect = 5.405e-161 Identity = 280/597 (46.90%), Postives = 396/597 (66.33%), Query Frame = 2
Query: 377 CIVVIEFLSWIQCEPLKNGACESLNDT-SCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKK 2164
C + + FL + C + + T +C G+V+P+W+P L+ GD++ R +YF + Y+FLG+SI+ADRFM+SIEVITS ER ++V++ + + VRIWN+TVSNLTLMALGSSAPEILLS+IE+ FEAGDLGP TIVGSAAFNLF+II CV VIP GE+RR KHL VF +TA+WSVFAY+WLYLI+AFFSP I++WE LTF FF LTV TAY+AD K+ KFL RY R + E+ LE+ GD L E+ R ++IE++REIR +NP+I P L++QA+ E+++R PKSRAFYR+QATR L G G+++KK ++++ ++ D K+ +N KIF DP HYTV+E+VG+F+V+V R G + + + V+Y TEDG+A AG DYI G + F + + + I ++DDD+FE DEHF++ L + R T+DG + ++ + +E+ P ATIM+LDDDHAG+F FE V E+CG +++ R SGARG V++P+R+ TA+ + E + F ++QTEA +++ I+D +YE+ +YF+IEL PI KK
Sbjct: 6 CWLAVAFLVALAGLADAGSNCSAADATRNCIDGLVIPIWRPFLDLTTGDRVLRGVLYFFVIAYMFLGISIVADRFMSSIEVITSMERTIVVKRPGLDPMAVQVRIWNDTVSNLTLMALGSSAPEILLSIIEVIARGFEAGDLGPNTIVGSAAFNLFMIIAICVVVIPKGEIRRQKHLDVFCVTATWSVFAYVWLYLILAFFSPGEIEIWEGALTFIFFPLTVFTAYMADIKLIQNKFLPHRYRRGSHGQMIATEAEEMKM---LENG-TQGDPA--LKAFEEHRQEFIELMREIRKQNPHITPTELQKQAEYEMISRGPKSRAFYRVQATRRLIGGGDIVKK-RIDKEHNKALDAAQEKQSRDNTCKIFLDPAHYTVLESVGSFDVVVGRDGGPDGLT---VMVDYFTEDGSANAGSDYIPVKGTLTFYPEDKHQKVTIEVVDDDVFEEDEHFYLRLCNLRVRTKDGIIIDPTRIGGLPVAQLEM--PNTATIMILDDDHAGVFGFEHDHFQVVENCGHLSLQMKRHSGARGKVIIPFRTVEGTASADKHFEMKEGEIVFEDNQTEALVEIGIVDTEQYERSDYFYIELSPPIWAKK 590 HSP 2 Score: 293.123 bits (749), Expect = 1.319e-83 Identity = 147/276 (53.26%), Postives = 202/276 (73.19%), Query Frame = 2
Query: 2204 GFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPS-----CLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKI 3016
G N EV T L EI +MGKPRLG+ + ++ I+ES EF+ +VD ++++ +GT SW+EQF+EA+ VS G++D ++ +D + + C+DYVMH LT+ WK+ FA +PPTDY GGW +F V I +IG LTAV+GDLAS FGC +G+ +AVTAI+FVA+GTS+PDTFASKV+A+ D AD++VGNVTGSNAVNVFLGIG+AWS+AA+YH+ +G+ F V G+LGFSV +FC A+ I ++LRRN++VGGELGGP L++
Sbjct: 675 GGNGDDEVTT---SLTPSQLEIAEMGKPRLGEFTKCQITIRESKEFQGIVDRMIKNANTRIMLGTHSWREQFMEALVVSAGDDDDDEGEDGEDGEEKEPEEPGCMDYVMHVLTVPWKLTFATIPPTDYFGGWATFVVAIFMIGVLTAVVGDLASQFGCWVGLKDAVTAISFVALGTSVPDTFASKVSAVQDKYADNAVGNVTGSNAVNVFLGIGIAWSMAAIYHWNQGTKFLVDPGNLGFSVLIFCTEAVLCIIVLVLRRNKKVGGELGGPIALRV 947 HSP 3 Score: 56.225 bits (134), Expect = 1.641e-7 Identity = 33/104 (31.73%), Postives = 55/104 (52.88%), Query Frame = 2
Query: 1865 DDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGV-VLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGI 2173
D+ IF + A V ES G ++ V R G G+ V+V Y + +A G+DYI V+ L F + + + ++DD+ +E+DE+F++ L + K GI
Sbjct: 361 DNTCKIF-LDPAHYTVLESVGSFDVVVGRDGGPDGLTVMVDYFTEDGSANAGSDYIPVKGTLTFYPEDKHQKVTIEVVDDDVFEEDEHFYLRLCNLRVRTKDGI 463
BLAST of slc8a-1 vs. Ensembl Fly
Match: Calx (gene:FBgn0013995 transcript:FBtr0309205) HSP 1 Score: 766.148 bits (1977), Expect = 0.000e+0 Identity = 437/902 (48.45%), Postives = 592/902 (65.63%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDH---ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKL------GLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIED--------------MGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRR-NRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIK 3094
C +G+VLPLW P +S+GD++ R FVYFV L+YLF+GVSIIADRFMA+IE ITS ER V+V+ N Q ++VRIWNETV+NLTLMALGSSAPEILLSVIEI +FE+GDLGPGTIVGSAA+NLF+II C+ IP GEVRRI+HL VF +TA +SVFAY+WL+LI++ F+P VI VWEA++T FF LTVL AY+A+ ++ + K++ + Y R N + + G+H E+ + + + + ++ R +YI ++ E+R K P+ D + LE AQ +VL R KSRAFYR+QATR + GSGN+++ K++ R D ++ G E+ ++ +++F+PGHYTVMEN G F V V R G T VEY T+DGTA+AG D++ G++ F G D++ I +IDDD+FE DE F+I L +P GV+L P IAT+M+LDDDHAGIF F ++ + ES G E+KV R SGARG V+VPY + +DTAT DY L F N+++E FI + I++++ YEKD F + +GEP L +S + F H E TH D+L ++ E+E + KPR G++ V I+ES EFK VD L+ +S +GTSSWKEQF +A+TV P + +E +D EE++PSC YV HF+ LFWKVLFAFVPPTD GG+V+F V I VIG +TA+IGD AS FGC + + ++VTAI FVA+GTS+PDTFAS +AA +D+ AD+ +GNVTGSNAVNVFLGIGLAW+IAAVYH G TF V+ G++GF+V +FC AL AI ++ RR ++ +G ELGGP+ K + V LW+ YV++ LE Y I+
Sbjct: 100 CSEGLVLPLWMPQRNISVGDRLVRGFVYFVLLIYLFVGVSIIADRFMAAIEAITSIERAVVVKGPNNTKQVMHVRIWNETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMIWIPAGEVRRIRHLRVFFVTALFSVFAYVWLWLILSVFTPGVILVWEAIVTLLFFPLTVLWAYIAERRLLVYKYMDKNY-RVNKRGTVVAGEHDQVEMDAEKGPKQPMVTSARGNDAEAFDEARREYITLLTELRQKYPDADLEQLEMMAQEQVLARSSKSRAFYRIQATRKMVGSGNLMR--KIQERAHSDLTEVKAQLHAGDDEEADDPIRMYFEPGHYTVMENCGEFEVRVVRRGD----ISTYASVEYETQDGTASAGTDFVGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIRLFNPSE-------------------GVKLAVPMIATVMILDDDHAGIFAFTDSVFEITESVGRFELKVMRYSGARGTVIVPYWTENDTATESKDYEGARGELVFENNESEKFIDLFILEESSYEKDVSFKVHIGEPRLAPDDTNKESFFNRFFEKHEHSGE-PTH-DELAAKIKEVEKKPVQDLTELDRILLLSKPRNGELTTAYVRIRESQEFKATVDKLVAKANVSAVLGTSSWKEQFKDALTVIPADE-SEFDNDDEEEEVPSCFSYVSHFVCLFWKVLFAFVPPTDICGGYVTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSSHGMTFNVEPGTIGFAVALFCGEALIAIMLIMFRRWHKGIGAELGGPKVSKYISAAILVFLWVFYVVICILEAYDVIR 972
BLAST of slc8a-1 vs. Ensembl Fly
Match: Calx (gene:FBgn0013995 transcript:FBtr0309202) HSP 1 Score: 764.992 bits (1974), Expect = 0.000e+0 Identity = 431/888 (48.54%), Postives = 588/888 (66.22%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDH---ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKL------GLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRR-NRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIK 3094
C +G+VLPLW P +S+GD++ R FVYFV L+YLF+GVSIIADRFMA+IE ITS ER V+V+ N Q ++VRIWNETV+NLTLMALGSSAPEILLSVIEI +FE+GDLGPGTIVGSAA+NLF+II C+ IP GEVRRI+HL VF +TA +SVFAY+WL+LI++ F+P VI VWEA++T FF LTVL AY+A+ ++ + K++ + Y R N + + G+H E+ + + + + ++ R +YI ++ E+R K P+ D + LE AQ +VL R KSRAFYR+QATR + GSGN+++ K++ R D ++ G E+ ++ +++F+PGHYTVMEN G F V V R G T VEY T+DGTA+AG D++ G++ F G D++ I +IDDD+FE DE F+I L +P GV+L P IAT+M+LDDDHAGIF F ++ + ES G E+KV R SGARG V+VPY + +DTAT DY L F N+++E FI + I++++ YEKD F + +GEP + + T + + EV+ Q +++ I + KPR G++ V I+ES EFK VD L+ +S +GTSSWKEQF +A+TV P + +E +D EE++PSC YV HF+ LFWKVLFAFVPPTD GG+V+F V I VIG +TA+IGD AS FGC + + ++VTAI FVA+GTS+PDTFAS +AA +D+ AD+ +GNVTGSNAVNVFLGIGLAW+IAAVYH G TF V+ G++GF+V +FC AL AI ++ RR ++ +G ELGGP+ K + V LW+ YV++ LE Y I+
Sbjct: 100 CSEGLVLPLWMPQRNISVGDRLVRGFVYFVLLIYLFVGVSIIADRFMAAIEAITSIERAVVVKGPNNTKQVMHVRIWNETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMIWIPAGEVRRIRHLRVFFVTALFSVFAYVWLWLILSVFTPGVILVWEAIVTLLFFPLTVLWAYIAERRLLVYKYMDKNY-RVNKRGTVVAGEHDQVEMDAEKGPKQPMVTSARGNDAEAFDEARREYITLLTELRQKYPDADLEQLEMMAQEQVLARSSKSRAFYRIQATRKMVGSGNLMR--KIQERAHSDLTEVKAQLHAGDDEEADDPIRMYFEPGHYTVMENCGEFEVRVVRRGD----ISTYASVEYETQDGTASAGTDFVGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIRLFNPSE-------------------GVKLAVPMIATVMILDDDHAGIFAFTDSVFEITESVGRFELKVMRYSGARGTVIVPYWTENDTATESKDYEGARGELVFENNESEKFIDLFILEESSYEKDVSFKVHIGEP-----------RLAPDSTHYPKIKEVEKKPVQDLTELDRILLLSKPRNGELTTAYVRIRESQEFKATVDKLVAKANVSAVLGTSSWKEQFKDALTVIPADE-SEFDNDDEEEEVPSCFSYVSHFVCLFWKVLFAFVPPTDICGGYVTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSSHGMTFNVEPGTIGFAVALFCGEALIAIMLIMFRRWHKGIGAELGGPKVSKYISAAILVFLWVFYVVICILEAYDVIR 949
BLAST of slc8a-1 vs. Ensembl Fly
Match: Calx (gene:FBgn0013995 transcript:FBtr0309204) HSP 1 Score: 763.837 bits (1971), Expect = 0.000e+0 Identity = 433/888 (48.76%), Postives = 588/888 (66.22%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDH---ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKL------GLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRR-NRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIK 3094
C +G+VLPLW P +S+GD++ R FVYFV L+YLF+GVSIIADRFMA+IE ITS ER V+V+ N Q ++VRIWNETV+NLTLMALGSSAPEILLSVIEI +FE+GDLGPGTIVGSAA+NLF+II C+ IP GEVRRI+HL VF +TA +SVFAY+WL+LI++ F+P VI VWEA++T FF LTVL AY+A+ ++ + K++ + Y R N + + G+H E+ + + + + ++ R +YI ++ E+R K P+ D + LE AQ +VL R KSRAFYR+QATR + GSGN+++ K++ R D ++ G E+ ++ +++F+PGHYTVMEN G F V V R G T VEY T+DGTA+AG D++ G++ F G D++ I +IDDD+FE DE F+I L +P GV+L P IAT+M+LDDDHAGIF F ++ + ES G E+KV R SGARG V+VPY + +DTAT DY L F N+++E FI + I++++ YEKD F + +GEP L + S P + EV+ Q +++ I + KPR G++ V I+ES EFK VD L+ +S +GTSSWKEQF +A+TV P + +E +D EE++PSC YV HF+ LFWKVLFAFVPPTD GG+V+F V I VIG +TA+IGD AS FGC + + ++VTAI FVA+GTS+PDTFAS +AA +D+ AD+ +GNVTGSNAVNVFLGIGLAW+IAAVYH G TF V+ G++GF+V +FC AL AI ++ RR ++ +G ELGGP+ K + V LW+ YV++ LE Y I+
Sbjct: 100 CSEGLVLPLWMPQRNISVGDRLVRGFVYFVLLIYLFVGVSIIADRFMAAIEAITSIERAVVVKGPNNTKQVMHVRIWNETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMIWIPAGEVRRIRHLRVFFVTALFSVFAYVWLWLILSVFTPGVILVWEAIVTLLFFPLTVLWAYIAERRLLVYKYMDKNY-RVNKRGTVVAGEHDQVEMDAEKGPKQPMVTSARGNDAEAFDEARREYITLLTELRQKYPDADLEQLEMMAQEQVLARSSKSRAFYRIQATRKMVGSGNLMR--KIQERAHSDLTEVKAQLHAGDDEEADDPIRMYFEPGHYTVMENCGEFEVRVVRRGD----ISTYASVEYETQDGTASAGTDFVGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIRLFNPSE-------------------GVKLAVPMIATVMILDDDHAGIFAFTDSVFEITESVGRFELKVMRYSGARGTVIVPYWTENDTATESKDYEGARGELVFENNESEKFIDLFILEESSYEKDVSFKVHIGEPRLAPEKH-EHSGEPTHDELAAKIKEVEKKPVQDLTELDRILLLSKPRNGELTTAYVRIRESQEFKATVDKLVAKANVSAVLGTSSWKEQFKDALTVIPADE-SEFDNDDEEEEVPSCFSYVSHFVCLFWKVLFAFVPPTDICGGYVTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSSHGMTFNVEPGTIGFAVALFCGEALIAIMLIMFRRWHKGIGAELGGPKVSKYISAAILVFLWVFYVVICILEAYDVIR 959
BLAST of slc8a-1 vs. Ensembl Fly
Match: Calx (gene:FBgn0013995 transcript:FBtr0309203) HSP 1 Score: 763.451 bits (1970), Expect = 0.000e+0 Identity = 433/890 (48.65%), Postives = 589/890 (66.18%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDH---ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKL------GLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTG--FNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRR-NRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIK 3094
C +G+VLPLW P +S+GD++ R FVYFV L+YLF+GVSIIADRFMA+IE ITS ER V+V+ N Q ++VRIWNETV+NLTLMALGSSAPEILLSVIEI +FE+GDLGPGTIVGSAA+NLF+II C+ IP GEVRRI+HL VF +TA +SVFAY+WL+LI++ F+P VI VWEA++T FF LTVL AY+A+ ++ + K++ + Y R N + + G+H E+ + + + + ++ R +YI ++ E+R K P+ D + LE AQ +VL R KSRAFYR+QATR + GSGN+++ K++ R D ++ G E+ ++ +++F+PGHYTVMEN G F V V R G T VEY T+DGTA+AG D++ G++ F G D++ I +IDDD+FE DE F+I L +P GV+L P IAT+M+LDDDHAGIF F ++ + ES G E+KV R SGARG V+VPY + +DTAT DY L F N+++E FI + I++++ YEKD F + +GEP L +S + F + EV+ Q +++ I + KPR G++ V I+ES EFK VD L+ +S +GTSSWKEQF +A+TV P + +E +D EE++PSC YV HF+ LFWKVLFAFVPPTD GG+V+F V I VIG +TA+IGD AS FGC + + ++VTAI FVA+GTS+PDTFAS +AA +D+ AD+ +GNVTGSNAVNVFLGIGLAW+IAAVYH G TF V+ G++GF+V +FC AL AI ++ RR ++ +G ELGGP+ K + V LW+ YV++ LE Y I+
Sbjct: 100 CSEGLVLPLWMPQRNISVGDRLVRGFVYFVLLIYLFVGVSIIADRFMAAIEAITSIERAVVVKGPNNTKQVMHVRIWNETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMIWIPAGEVRRIRHLRVFFVTALFSVFAYVWLWLILSVFTPGVILVWEAIVTLLFFPLTVLWAYIAERRLLVYKYMDKNY-RVNKRGTVVAGEHDQVEMDAEKGPKQPMVTSARGNDAEAFDEARREYITLLTELRQKYPDADLEQLEMMAQEQVLARSSKSRAFYRIQATRKMVGSGNLMR--KIQERAHSDLTEVKAQLHAGDDEEADDPIRMYFEPGHYTVMENCGEFEVRVVRRGD----ISTYASVEYETQDGTASAGTDFVGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIRLFNPSE-------------------GVKLAVPMIATVMILDDDHAGIFAFTDSVFEITESVGRFELKVMRYSGARGTVIVPYWTENDTATESKDYEGARGELVFENNESEKFIDLFILEESSYEKDVSFKVHIGEPRLAPDDTNKESFFNRFFDDELAAKIKEVEKKPVQDLTELDRILLLSKPRNGELTTAYVRIRESQEFKATVDKLVAKANVSAVLGTSSWKEQFKDALTVIPADE-SEFDNDDEEEEVPSCFSYVSHFVCLFWKVLFAFVPPTDICGGYVTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSSHGMTFNVEPGTIGFAVALFCGEALIAIMLIMFRRWHKGIGAELGGPKVSKYISAAILVFLWVFYVVICILEAYDVIR 962
BLAST of slc8a-1 vs. Ensembl Fly
Match: Calx (gene:FBgn0013995 transcript:FBtr0083999) HSP 1 Score: 763.451 bits (1970), Expect = 0.000e+0 Identity = 431/888 (48.54%), Postives = 586/888 (65.99%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDH---ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKL------GLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRR-NRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIK 3094
C +G+VLPLW P +S+GD++ R FVYFV L+YLF+GVSIIADRFMA+IE ITS ER V+V+ N Q ++VRIWNETV+NLTLMALGSSAPEILLSVIEI +FE+GDLGPGTIVGSAA+NLF+II C+ IP GEVRRI+HL VF +TA +SVFAY+WL+LI++ F+P VI VWEA++T FF LTVL AY+A+ ++ + K++ + Y R N + + G+H E+ + + + + ++ R +YI ++ E+R K P+ D + LE AQ +VL R KSRAFYR+QATR + GSGN+++ K++ R D ++ G E+ ++ +++F+PGHYTVMEN G F V V R G T VEY T+DGTA+AG D++ G++ F G D++ I +IDDD+FE DE F+I L +P GV+L P IAT+M+LDDDHAGIF F ++ + ES G E+KV R SGARG V+VPY + +DTAT DY L F N+++E FI + I++++ YEKD F + +GEP L + + EV+ Q +++ I + KPR G++ V I+ES EFK VD L+ +S +GTSSWKEQF +A+TV P + +E +D EE++PSC YV HF+ LFWKVLFAFVPPTD GG+V+F V I VIG +TA+IGD AS FGC + + ++VTAI FVA+GTS+PDTFAS +AA +D+ AD+ +GNVTGSNAVNVFLGIGLAW+IAAVYH G TF V+ G++GF+V +FC AL AI ++ RR ++ +G ELGGP+ K + V LW+ YV++ LE Y I+
Sbjct: 100 CSEGLVLPLWMPQRNISVGDRLVRGFVYFVLLIYLFVGVSIIADRFMAAIEAITSIERAVVVKGPNNTKQVMHVRIWNETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMIIAVCMIWIPAGEVRRIRHLRVFFVTALFSVFAYVWLWLILSVFTPGVILVWEAIVTLLFFPLTVLWAYIAERRLLVYKYMDKNY-RVNKRGTVVAGEHDQVEMDAEKGPKQPMVTSARGNDAEAFDEARREYITLLTELRQKYPDADLEQLEMMAQEQVLARSSKSRAFYRIQATRKMVGSGNLMR--KIQERAHSDLTEVKAQLHAGDDEEADDPIRMYFEPGHYTVMENCGEFEVRVVRRGD----ISTYASVEYETQDGTASAGTDFVGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIRLFNPSE-------------------GVKLAVPMIATVMILDDDHAGIFAFTDSVFEITESVGRFELKVMRYSGARGTVIVPYWTENDTATESKDYEGARGELVFENNESEKFIDLFILEESSYEKDVSFKVHIGEPRLAPDDELAAK-----------IKEVEKKPVQDLTELDRILLLSKPRNGELTTAYVRIRESQEFKATVDKLVAKANVSAVLGTSSWKEQFKDALTVIPADE-SEFDNDDEEEEVPSCFSYVSHFVCLFWKVLFAFVPPTDICGGYVTFVVSIFVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSSHGMTFNVEPGTIGFAVALFCGEALIAIMLIMFRRWHKGIGAELGGPKVSKYISAAILVFLWVFYVVICILEAYDVIR 949
BLAST of slc8a-1 vs. Ensembl Zebrafish
Match: slc8a1a (solute carrier family 8 member 1a [Source:ZFIN;Acc:ZDB-GENE-050809-1]) HSP 1 Score: 856.284 bits (2211), Expect = 0.000e+0 Identity = 470/901 (52.16%), Postives = 623/901 (69.15%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYL--RKNVKSYALEGDHELHCNHSLE------DAH----LDG--DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENN------NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
CK+G++LP+W PV+ S GDK+ARA VYFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIP+GE R++KHL VF +TA+WS+FAY WLYLI+A SP +++VWE LLT FFF + VL A+VAD ++ K++ +RY +K EG+ EL +E ++H LDG D ++ + ++ R + ++++E++ K+P + + L E A VL++ KSRAFYR QATR +TG+GN++KK + Q LG+ E + + KIFFDPG Y +EN GT + V R G D + + VEY TEDGTA AG DY T GV++F+ GE +K I + IIDDDIFE DEHF ++L + + +++ + + G+ L P AT+ + DDDHAGIF FEE ++ES G E+KV R+SGARGVV++PY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP LV+ + + T K D+ I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW++QFVEAITV+ G++D E+ +EK+PSC DYVMHFLT+FWKVLFAFVPPTDY GW F V I++IG LTA IGD+AS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA++H +G FRV G+L FSVT+F IFA IA ++ RR +GGELGGPRH KI TT F LW++Y+ILSS+E YC IKGF
Sbjct: 59 CKEGVILPIWTPVNP-SFGDKLARATVYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPEGEHRKVKHLRVFFVTATWSIFAYTWLYLILAVISPGIVEVWEGLLTLFFFPICVLFAWVADRRLLFYKYVYKRYRVGKKRGIIIETEGEPELQSKADIEMDGGMLNSHAEEFLDGAVDNEDKDADEDEARREMAKILKELKQKHPEKEMEQLVELANYHVLSQQQKSRAFYRCQATRLMTGAGNILKKHAAD----QARKALGIHELRSEVSDNDISSKIFFDPGTYQCLENCGTVALNVVRRGGD---LTSTVSVEYRTEDGTANAGSDYQFTEGVIIFKPGETEKEIRVDIIDDDIFEEDEHFLVHLSNVKVISEGANNGNPGTNHVDALAGLGL--PSTATVTIFDDDHAGIFLFEEPIVHISESIGMMEVKVVRTSGARGVVVIPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTIQINIIDDEEYEKNKNFFLEIGEPQLVEMSERKEDGEEETLT--------KKEKDE-----RRIAEMGRPTLGEHVKLEVIIEESYEFKSTVDKLIKKTNLALLVGTNSWRDQFVEAITVNSGDDDDEEC---GQEKMPSCFDYVMHFLTVFWKVLFAFVPPTDYWNGWACFIVSIMMIGVLTAFIGDIASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIFHQSQGRQFRVDPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRHPKIITTTLFFSLWLMYIILSSMEAYCIIKGF 933
BLAST of slc8a-1 vs. Ensembl Zebrafish
Match: slc8a1a (solute carrier family 8 member 1a [Source:ZFIN;Acc:ZDB-GENE-050809-1]) HSP 1 Score: 852.432 bits (2201), Expect = 0.000e+0 Identity = 477/930 (51.29%), Postives = 632/930 (67.96%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYL--RKNVKSYALEGDHELHCNHSLE------DAH----LDG--DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENN------NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSD--------------QLVSQSSE---------------IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
CK+G++LP+W PV+ S GDK+ARA VYFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIP+GE R++KHL VF +TA+WS+FAY WLYLI+A SP +++VWE LLT FFF + VL A+VAD ++ K++ +RY +K EG+ EL +E ++H LDG D ++ + ++ R + ++++E++ K+P + + L E A VL++ KSRAFYR QATR +TG+GN++KK + Q LG+ E + + KIFFDPG Y +EN GT + V R G D + + VEY TEDGTA AG DY T GV++F+ GE +K I + IIDDDIFE DEHF ++L + + +++ + + G+ L P AT+ + DDDHAGIF FEE ++ES G E+KV R+SGARGVV++PY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP LV+ K+ + E GF VKT D ++S S + I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW++QFVEAITV+ G++D E+ +EK+PSC DYVMHFLT+FWKVLFAFVPPTDY GW F V I++IG LTA IGD+AS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA++H +G FRV G+L FSVT+F IFA IA ++ RR +GGELGGPRH KI TT F LW++Y+ILSS+E YC IKGF
Sbjct: 59 CKEGVILPIWTPVNP-SFGDKLARATVYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPEGEHRKVKHLRVFFVTATWSIFAYTWLYLILAVISPGIVEVWEGLLTLFFFPICVLFAWVADRRLLFYKYVYKRYRVGKKRGIIIETEGEPELQSKADIEMDGGMLNSHAEEFLDGAVDNEDKDADEDEARREMAKILKELKQKHPEKEMEQLVELANYHVLSQQQKSRAFYRCQATRLMTGAGNILKKHAAD----QARKALGIHELRSEVSDNDISSKIFFDPGTYQCLENCGTVALNVVRRGGD---LTSTVSVEYRTEDGTANAGSDYQFTEGVIIFKPGETEKEIRVDIIDDDIFEEDEHFLVHLSNVKVISEGANNGNPGTNHVDALAGLGL--PSTATVTIFDDDHAGIFLFEEPIVHISESIGMMEVKVVRTSGARGVVVIPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTIQINIIDDEEYEKNKNFFLEIGEPQLVEMSE-RKAMLLHECGGF-----VKTGRDVYRKVQGRDKPIPSTIISISEDGEEETLTKKEKDERRIAEMGRPTLGEHVKLEVIIEESYEFKSTVDKLIKKTNLALLVGTNSWRDQFVEAITVNSGDDDDEEC---GQEKMPSCFDYVMHFLTVFWKVLFAFVPPTDYWNGWACFIVSIMMIGVLTAFIGDIASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIFHQSQGRQFRVDPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRHPKIITTTLFFSLWLMYIILSSMEAYCIIKGF 969
BLAST of slc8a-1 vs. Ensembl Zebrafish
Match: slc8a1a (solute carrier family 8 member 1a [Source:ZFIN;Acc:ZDB-GENE-050809-1]) HSP 1 Score: 850.892 bits (2197), Expect = 0.000e+0 Identity = 474/931 (50.91%), Postives = 633/931 (67.99%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYL--RKNVKSYALEGDHELHCNHSLE------DAH----LDG--DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENN------NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTAT-GGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKP-----------GIGKSNIPKEFTGFNHVSEVKTHSDQL------VSQSSE-------------IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
CK+G++LP+W PV+ S GDK+ARA VYFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIP+GE R++KHL VF +TA+WS+FAY WLYLI+A SP +++VWE LLT FFF + VL A+VAD ++ K++ +RY +K EG+ EL +E ++H LDG D ++ + ++ R + ++++E++ K+P + + L E A VL++ KSRAFYR QATR +TG+GN++KK + Q LG+ E + + KIFFDPG Y +EN GT + V R G D + + VEY TEDGTA AG DY T GV++F+ GE +K I + IIDDDIFE DEHF ++L + + +++ + + G+ L P AT+ + DDDHAGIF FEE ++ES G E+KV R+SGARGVV++PY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP LV+ G K++ K+ G + +V+ + +S+ E I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW++QFVEAITV+ G++D E+ +EK+PSC DYVMHFLT+FWKVLFAFVPPTDY GW F V I++IG LTA IGD+AS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA++H +G FRV G+L FSVT+F IFA IA ++ RR +GGELGGPRH KI TT F LW++Y+ILSS+E YC IKGF
Sbjct: 59 CKEGVILPIWTPVNP-SFGDKLARATVYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPEGEHRKVKHLRVFFVTATWSIFAYTWLYLILAVISPGIVEVWEGLLTLFFFPICVLFAWVADRRLLFYKYVYKRYRVGKKRGIIIETEGEPELQSKADIEMDGGMLNSHAEEFLDGAVDNEDKDADEDEARREMAKILKELKQKHPEKEMEQLVELANYHVLSQQQKSRAFYRCQATRLMTGAGNILKKHAAD----QARKALGIHELRSEVSDNDISSKIFFDPGTYQCLENCGTVALNVVRRGGD---LTSTVSVEYRTEDGTANAGSDYQFTEGVIIFKPGETEKEIRVDIIDDDIFEEDEHFLVHLSNVKVISEGANNGNPGTNHVDALAGLGL--PSTATVTIFDDDHAGIFLFEEPIVHISESIGMMEVKVVRTSGARGVVVIPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTIQINIIDDEEYEKNKNFFLEIGEPQLVEMSERKAMLLHECGGFVKTD--KQLYGRDVYRKVQGRDKPIPSTIISISEDGEEETLTKKEKDERRIAEMGRPTLGEHVKLEVIIEESYEFKSTVDKLIKKTNLALLVGTNSWRDQFVEAITVNSGDDDDEEC---GQEKMPSCFDYVMHFLTVFWKVLFAFVPPTDYWNGWACFIVSIMMIGVLTAFIGDIASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIFHQSQGRQFRVDPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRHPKIITTTLFFSLWLMYIILSSMEAYCIIKGF 974
BLAST of slc8a-1 vs. Ensembl Zebrafish
Match: slc8a1b (solute carrier family 8 member 1b [Source:ZFIN;Acc:ZDB-GENE-060110-3]) HSP 1 Score: 845.499 bits (2183), Expect = 0.000e+0 Identity = 483/904 (53.43%), Postives = 628/904 (69.47%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHELHCNHSLE------DAH----LDGD-----KKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNN-QKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIE----PFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
C G++LP+W+P + S GDK+ARA VYFV+L+Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSVIE+CG NFEAGDLGP TIVGSAAFN+F+IIG CVYV+PDGE R++KHL VF +TA+WS+FAY+W+YLI+A SP ++QVWE LLT FFF + V+ A++AD ++ K++ +RY + +E GD L +E ++H LDG + ++L E ++ R + ++++E++ K+P+ + + L E A +VL++ KSRAFYR QATR +TG+GN++KK ++ R + ++ EN+ KIFFDP Y +EN GT V V R G D + VE+ TEDGTA AG DY T G V+F+ GE QK I + IIDDDIFE DE+F I+L + R V + + + TE N VE I P AT+ + DDDHAGIF FEE T V+ES G E+KV R+SGARGVV VPY++ TA GG D+ + +LEF ND+ IKV IIDD EYEK++ F +E+G+P LV+ K V E + + I +MGKP LGD ++VII+ES EFK+ VD L++ L+ +GT+SW++QF+EAITVS GE+D ++ EEKLPSC DYVMHFLT+FWKVLFAFVPPTDY GW F V I++IG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH KG+ FRV+ G+L FSVT+F IFA +A ++ RR +GGELGGPR K TT+ FV LW++Y++ SSLE YCHIKGF
Sbjct: 59 CAPGVILPVWEPPNP-SFGDKVARATVYFVALVYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFEAGDLGPSTIVGSAAFNMFVIIGICVYVVPDGEHRKVKHLRVFFVTAAWSIFAYLWMYLILAVLSPGIVQVWEGLLTLFFFPICVVFAWIADRRLLFYKYVYKRYRAGKHRGMIIETEGDRPLPSKVDIEMDGKMLNSHAVDFLDGTLALELEDKDLDE-DEARREMAKILKELKQKHPDKEVEQLIELANYQVLSQQQKSRAFYRCQATRLMTGAGNILKKHAADQARKAVSMHEVRSDTGENDPISKIFFDPCSYQCLENCGTVAVNVIRRGGD---LNQTVSVEFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLIHLSNVRVVHEGDEP----ETTEAN--HVETIATLGLPSTATVTIFDDDHAGIFTFEEPVTHVSESVGVMEVKVLRTSGARGVVSVPYKTIEGTARGGGEDFEDSHGFLEFQNDEIFKTIKVRIIDDEEYEKNKSFFLEIGDPQLVETD-------EKRDEEKEVVKEEEEPLTGEEEEERRIAEMGKPMLGDHPRVEVIIEESYEFKNTVDKLIKKTNLALLVGTNSWRDQFIEAITVSAGEDDDDEE--CGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTDYWNGWACFVVSIIMIGVLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHNSKGNDFRVEPGNLAFSVTLFTIFAFICVAVLMYRRRPDIGGELGGPRTAKALTTMLFVSLWLLYILFSSLEAYCHIKGF 942
BLAST of slc8a-1 vs. Ensembl Zebrafish
Match: slc8a1a (solute carrier family 8 member 1a [Source:ZFIN;Acc:ZDB-GENE-050809-1]) HSP 1 Score: 845.499 bits (2183), Expect = 0.000e+0 Identity = 467/901 (51.83%), Postives = 618/901 (68.59%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYL--RKNVKSYALEGDHELHCNHSLE------DAH----LDG--DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENN------NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
CK+G++LP+W PV+ S GDK+ARA VYFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIP+GE R++KHL VF +TA+WS+FAY WLYLI+A SP +++VWE LLT FFF + VL A+VAD ++ K++ +RY +K EG+ EL +E ++H LDG D ++ + ++ R + ++++E++ K+P + + L E A VL++ KSRAFYR QATR +TG+GN++KK + Q LG+ E + + KIFFDPG Y +EN GT + V R G D + + VEY TEDGTA AG DY T GV++F+ GE +K I + IIDDDIFE DEHF ++L + + +++ + + G+ L P AT+ + DDDHAGIF FEE ++ES G E+KV R+SGARGVV++PY++ TA GG D+ + LEF ND+ IKV I+D EY+K F IEL EP ++ G+ E +T + + I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW++QFVEAITV+ G++D E+ +EK+PSC DYVMHFLT+FWKVLFAFVPPTDY GW F V I++IG LTA IGD+AS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA++H +G FRV G+L FSVT+F IFA IA ++ RR +GGELGGPRH KI TT F LW++Y+ILSS+E YC IKGF
Sbjct: 59 CKEGVILPIWTPVNP-SFGDKLARATVYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPEGEHRKVKHLRVFFVTATWSIFAYTWLYLILAVISPGIVEVWEGLLTLFFFPICVLFAWVADRRLLFYKYVYKRYRVGKKRGIIIETEGEPELQSKADIEMDGGMLNSHAEEFLDGAVDNEDKDADEDEARREMAKILKELKQKHPEKEMEQLVELANYHVLSQQQKSRAFYRCQATRLMTGAGNILKKHAAD----QARKALGIHELRSEVSDNDISSKIFFDPGTYQCLENCGTVALNVVRRGGD---LTSTVSVEYRTEDGTANAGSDYQFTEGVIIFKPGETEKEIRVDIIDDDIFEEDEHFLVHLSNVKVISEGANNGNPGTNHVDALAGLGL--PSTATVTIFDDDHAGIFLFEEPIVHISESIGMMEVKVVRTSGARGVVVIPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTIKVKILDHEEYDKHANFFIELQEPEWRRR-------------GWTEDGEEETLTKK-EKDERRIAEMGRPTLGEHVKLEVIIEESYEFKSTVDKLIKKTNLALLVGTNSWRDQFVEAITVNSGDDDDEEC---GQEKMPSCFDYVMHFLTVFWKVLFAFVPPTDYWNGWACFIVSIMMIGVLTAFIGDIASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIFHQSQGRQFRVDPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRHPKIITTTLFFSLWLMYIILSSMEAYCIIKGF 932
BLAST of slc8a-1 vs. Ensembl Xenopus
Match: SLC8A3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:NCBI gene;Acc:100487508]) HSP 1 Score: 832.787 bits (2150), Expect = 0.000e+0 Identity = 472/905 (52.15%), Postives = 631/905 (69.72%), Query Frame = 2
Query: 422 LKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH--------ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++N +C CK+G++LP+W P S+GDKIAR VYFV+++Y+FLGVSIIADRFMASIEVITS+ER+++++K NGE T +RIWNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIII CVYVIPDGEVR++KHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + V+ A+VAD ++ K++ ++Y ++ +E DH ++ +H L+ L+ D KE ++++R D I +++E++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + S + L E E KI+FDP Y +EN G + V R G D I+KT+ V+Y TEDG+A AG DY T G ++F+SGE QK + IIDDDIFE DEHFF+ L + R +T+ + N + L+ P+IA+I +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG DY + LEF ND+T I+V IID+ EYE+ E F I LGEP +K+ GI +++ +E K ++ ++ I +MGKP LG+ +++V+I+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+YL GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y ++G F V +G+L FSVT+F IFA I+ +L RR +GGELGGP+ ++AT++ FV LW++Y++ ++LE YC+IKGF
Sbjct: 42 VQNNSCS--GSYECKEGVILPIWYP-ENPSMGDKIARVIVYFVAMIYMFLGVSIIADRFMASIEVITSQEREIVIKKPNGETSTTTIRIWNETVSNLTLMALGSSAPEILLSLIEVCGHGFLAGDLGPSTIVGSAAFNMFIIIALCVYVIPDGEVRKVKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVVLAWVADKRLLFYKYMHKKYRTDKHRAIMIETEADHPKGIEMDGKVMNSHFLDGNLLNMDGKE----VDESRRDMIRILKELKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQSKRSSSLQDICLDESEEFVSKIYFDPCSYQCLENCGAVLLTVVRKGGD--ISKTVF-VDYKTEDGSANAGADYEFTEGTLVFKSGETQKEFSVGIIDDDIFEEDEHFFVRLSNIR-ITEAPEPAEPNSFSYPK---AVLVSPYIASITILDDDHAGIFTFECDIIRVSESIGVMEVKVLRTSGARGTVIVPFRTIEGTAKGGGEDYEDSYGELEFKNDETVKTIRVKIIDEEEYERQESFFIALGEPKWMKR-GISAADL----------TERKLSVEE--EEAKRIAEMGKPILGEHPKLEVVIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEEEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYLNGWACFVVSIIIIGILTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKVAATQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAYQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHIGGELGGPKGYRLATSLLFVSLWLLYILFATLEAYCYIKGF 917
BLAST of slc8a-1 vs. Ensembl Xenopus
Match: SLC8A3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:NCBI gene;Acc:100487508]) HSP 1 Score: 830.861 bits (2145), Expect = 0.000e+0 Identity = 471/905 (52.04%), Postives = 628/905 (69.39%), Query Frame = 2
Query: 422 LKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH--------ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++N +C CK+G++LP+W P S+GDKIAR VYFV+++Y+FLGVSIIADRFMASIEVITS+ER+++++K NGE T +RIWNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIII CVYVIPDGEVR++KHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + V+ A+VAD ++ K++ ++Y ++ +E DH ++ +H L+ L+ D KE ++++R D I +++E++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + S + L E E KI+FDP Y +EN G + V R G D I+KT+ V+Y TEDG+A AG DY T G ++F+SGE QK + IIDDDIFE DEHFF+ L + R +T+ + N + L+ P+IA+I +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG DY + LEF ND+T I+V IID+ EYE+ E F I LGEP +K+ I ++E K ++ ++ I +MGKP LG+ +++V+I+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+YL GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y ++G F V +G+L FSVT+F IFA I+ +L RR +GGELGGP+ ++AT++ FV LW++Y++ ++LE YC+IKGF
Sbjct: 42 VQNNSCS--GSYECKEGVILPIWYP-ENPSMGDKIARVIVYFVAMIYMFLGVSIIADRFMASIEVITSQEREIVIKKPNGETSTTTIRIWNETVSNLTLMALGSSAPEILLSLIEVCGHGFLAGDLGPSTIVGSAAFNMFIIIALCVYVIPDGEVRKVKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVVLAWVADKRLLFYKYMHKKYRTDKHRAIMIETEADHPKGIEMDGKVMNSHFLDGNLLNMDGKE----VDESRRDMIRILKELKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQSKRSSSLQDICLDESEEFVSKIYFDPCSYQCLENCGAVLLTVVRKGGD--ISKTVF-VDYKTEDGSANAGADYEFTEGTLVFKSGETQKEFSVGIIDDDIFEEDEHFFVRLSNIR-ITEAPEPAEPNSFSYPK---AVLVSPYIASITILDDDHAGIFTFECDIIRVSESIGVMEVKVLRTSGARGTVIVPFRTIEGTAKGGGEDYEDSYGELEFKNDETVKTIRVKIIDEEEYERQESFFIALGEPKWMKR------GISALLLNQADLTERKLSVEE--EEAKRIAEMGKPILGEHPKLEVVIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEEEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYLNGWACFVVSIIIIGILTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKVAATQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAYQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHIGGELGGPKGYRLATSLLFVSLWLLYILFATLEAYCYIKGF 922
BLAST of slc8a-1 vs. Ensembl Xenopus
Match: SLC8A2 (solute carrier family 8 member A2 [Source:NCBI gene;Acc:100495074]) HSP 1 Score: 829.321 bits (2141), Expect = 0.000e+0 Identity = 471/933 (50.48%), Postives = 622/933 (66.67%), Query Frame = 2
Query: 362 LLFGSCIVVIEFLSWIQCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSY----------ALEGDHELHCNHSLEDAHLDGDKKENLT------ELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLG---LKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
LL S +++I L+ + L+NG CE+ D C+ GI+LP+W+P S+GDK+ARA VYFV+++YLFLGVSIIADRFMASIEVITS+E+++ + K NGE VRIWNETVSNLTLMALGSSAPEILLSVIE+CG F AG+LGPGTIVGSAAFN+F+II CVYVIP+GE R+IKH VF +TA+WS+FAYIWLY+I+A SP+ +QVWEAL+T FF V+ A++AD ++ K++ +RY + ++E D +L + + D +++ EL+++R + I +++E++ K P + L E A L KSRAFYR+QATR + G+GNV+KK + S+ P L E N KIFF P +Y +EN G + V G D + V+Y TEDG+A AG DY + G ++F+ GE QK +++ IIDDDIFE DEHFF+ L + R +G + + + L+ P IAT+ +LDDDHAGIF FEE V+ES G E+KV R+SGARG V++PYR+ TA GG DY + LEF ND+T ++V I+DD EYEK E F I L EP +K+ GI + ++ +E + ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ IGT SW+EQF EAITVS D E+ DD EE+LPSC DYVMHFLT+FWKVLFAFVPPT+Y GW F+VCI ++G LTAVIGDLAS FGCT+G+ ++VTA+ FVA+GTSLPDTFASKVAA+ D AD+ +GNVTGSNAVNVFLGIG+AWS+AA+Y +G F V++GSL FSVT+F IFA I +L RR +GGELGG R K T + F+GLW++Y++ SSLE YCHIKGF
Sbjct: 4 LLRISALMLI-ILTLTSSKELENGTCEAAKDGKCQPGILLPVWEP-QNPSMGDKVARAVVYFVAMLYLFLGVSIIADRFMASIEVITSQEKEITLTKPNGETSVATVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHGFHAGELGPGTIVGSAAFNMFVIIAICVYVIPNGESRKIKHPRVFFVTATWSIFAYIWLYIILAVTSPKRVQVWEALVTLLFFPACVVLAWIADKRLLFYKYVYKRYRADKRRGIIIETEGEFPKSIEMDGKLGASAVVAPETKDAGMQDSAAAAAEAKELDESRKEVIRILKELKQKYPERELDQLVEMANYYALLHQQKSRAFYRIQATRMMIGAGNVLKKHAADH--SRKPATLQEVTSDSSEENTSKIFFQPSNYQCLENCGFVTLNVACQGGD---GASTFYVDYKTEDGSANAGSDYEYSEGTLIFKPGETQKELKVGIIDDDIFEEDEHFFVRLMNLRVGDAEG----MFEPDGEGRPKARLVSPLIATVTILDDDHAGIFTFEEKLVHVSESVGILEVKVVRNSGARGTVVIPYRTMEGTARGGGVDYEDAYGELEFQNDETLKTLQVKIVDDEEYEKQENFFIILEEPRWMKR-GISALLLNQDEDDKKLTAEEE--------EAKRIAEMGKPILGEHSKLEVIIEESYEFKSTVDKLIKKTNLALVIGTHSWREQFTEAITVSA--GDEEEEDDGREERLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFFVCISIVGILTAVIGDLASHFGCTVGLKDSVTAVVFVALGTSLPDTFASKVAAMQDQYADACIGNVTGSNAVNVFLGIGVAWSVAAIYWAIQGKDFIVETGSLAFSVTLFTIFAFINIGVLLYRRRPHIGGELGGSRLSKTLTAMLFIGLWLLYILFSSLEAYCHIKGF 914
BLAST of slc8a-1 vs. Ensembl Xenopus
Match: SLC8A3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:NCBI gene;Acc:100487508]) HSP 1 Score: 828.935 bits (2140), Expect = 0.000e+0 Identity = 471/905 (52.04%), Postives = 631/905 (69.72%), Query Frame = 2
Query: 422 LKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH--------ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++N +C CK+G++LP+W P S+GDKIAR VYFV+++Y+FLGVSIIADRFMASIEVITS+ER+++++K NGE T +RIWNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIII CVYVIPDGEVR++KHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + V+ A+VAD ++ K++ ++Y ++ +E DH ++ +H L+ L+ D KE ++++R D I +++E++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + S + L E E KI+FDP Y +EN G + V R G D I+KT+ V+Y TEDG+A AG DY T G ++F+SGE QK + IIDDDIFE DEHFF+ L + R +T+ + N + L+ P+IA+I +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG DY + LEF ND+T I++ I DD EYEK++ F IEL EP LV + K+ + + ++E K ++ ++ I +MGKP LG+ +++V+I+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+YL GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y ++G F V +G+L FSVT+F IFA I+ +L RR +GGELGGP+ ++AT++ FV LW++Y++ ++LE YC+IKGF
Sbjct: 42 VQNNSCS--GSYECKEGVILPIWYP-ENPSMGDKIARVIVYFVAMIYMFLGVSIIADRFMASIEVITSQEREIVIKKPNGETSTTTIRIWNETVSNLTLMALGSSAPEILLSLIEVCGHGFLAGDLGPSTIVGSAAFNMFIIIALCVYVIPDGEVRKVKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVVLAWVADKRLLFYKYMHKKYRTDKHRAIMIETEADHPKGIEMDGKVMNSHFLDGNLLNMDGKE----VDESRRDMIRILKELKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQSKRSSSLQDICLDESEEFVSKIYFDPCSYQCLENCGAVLLTVVRKGGD--ISKTVF-VDYKTEDGSANAGADYEFTEGTLVFKSGETQKEFSVGIIDDDIFEEDEHFFVRLSNIR-ITEAPEPAEPNSFSYPK---AVLVSPYIASITILDDDHAGIFTFECDIIRVSESIGVMEVKVLRTSGARGTVIVPFRTIEGTAKGGGEDYEDSYGELEFKNDETVKTIQIKIFDDEEYEKNKTFFIELREPHLVDL-SVQKALLLNQ----ADLTERKLSVEE--EEAKRIAEMGKPILGEHPKLEVVIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEEEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYLNGWACFVVSIIIIGILTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKVAATQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAYQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHIGGELGGPKGYRLATSLLFVSLWLLYILFATLEAYCYIKGF 923
BLAST of slc8a-1 vs. Ensembl Xenopus
Match: SLC8A3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:NCBI gene;Acc:100487508]) HSP 1 Score: 828.55 bits (2139), Expect = 0.000e+0 Identity = 470/905 (51.93%), Postives = 628/905 (69.39%), Query Frame = 2
Query: 422 LKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH--------ELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++N +C CK+G++LP+W P S+GDKIAR VYFV+++Y+FLGVSIIADRFMASIEVITS+ER+++++K NGE T +RIWNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIII CVYVIPDGEVR++KHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + V+ A+VAD ++ K++ ++Y ++ +E DH ++ +H L+ L+ D KE ++++R D I +++E++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + S + L E E KI+FDP Y +EN G + V R G D I+KT+ V+Y TEDG+A AG DY T G ++F+SGE QK + IIDDDIFE DEHFF+ L + R +T+ + N + L+ P+IA+I +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG DY + LEF ND+T I++ I DD EYEK++ F IEL EP LV +++ +E K ++ ++ I +MGKP LG+ +++V+I+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+YL GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y ++G F V +G+L FSVT+F IFA I+ +L RR +GGELGGP+ ++AT++ FV LW++Y++ ++LE YC+IKGF
Sbjct: 42 VQNNSCS--GSYECKEGVILPIWYP-ENPSMGDKIARVIVYFVAMIYMFLGVSIIADRFMASIEVITSQEREIVIKKPNGETSTTTIRIWNETVSNLTLMALGSSAPEILLSLIEVCGHGFLAGDLGPSTIVGSAAFNMFIIIALCVYVIPDGEVRKVKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVVLAWVADKRLLFYKYMHKKYRTDKHRAIMIETEADHPKGIEMDGKVMNSHFLDGNLLNMDGKE----VDESRRDMIRILKELKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQSKRSSSLQDICLDESEEFVSKIYFDPCSYQCLENCGAVLLTVVRKGGD--ISKTVF-VDYKTEDGSANAGADYEFTEGTLVFKSGETQKEFSVGIIDDDIFEEDEHFFVRLSNIR-ITEAPEPAEPNSFSYPK---AVLVSPYIASITILDDDHAGIFTFECDIIRVSESIGVMEVKVLRTSGARGTVIVPFRTIEGTAKGGGEDYEDSYGELEFKNDETVKTIQIKIFDDEEYEKNKTFFIELREPHLVDLSVQKAADL----------TERKLSVEE--EEAKRIAEMGKPILGEHPKLEVVIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEEEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYLNGWACFVVSIIIIGILTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKVAATQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAYQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHIGGELGGPKGYRLATSLLFVSLWLLYILFATLEAYCYIKGF 918
BLAST of slc8a-1 vs. Ensembl Mouse
Match: Slc8a3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:MGI Symbol;Acc:MGI:107976]) HSP 1 Score: 833.943 bits (2153), Expect = 0.000e+0 Identity = 473/906 (52.21%), Postives = 623/906 (68.76%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQ---DGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG N T LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D I+KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R + +G +I L + L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I+V I+D+ EYE+ E F I LGEP +++ G + V++ K ++ ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ED D+ EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA ++ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NFTPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHTDEPEDFASKVFFDPCSYQCLENCGAVLLTVVRKGGD--ISKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRVEEEQLAEGMLPAI--LNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDAYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMER-------------GISEVTDRKLTVEE--EEAKRIAEMGKPVLGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSA--GGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAMQGQEFHVSAGTLAFSVTLFTIFAFVCLSVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 921
BLAST of slc8a-1 vs. Ensembl Mouse
Match: Slc8a3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:MGI Symbol;Acc:MGI:107976]) HSP 1 Score: 833.558 bits (2152), Expect = 0.000e+0 Identity = 475/906 (52.43%), Postives = 622/906 (68.65%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQ---DGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG N T LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D I+KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R + +G +I L + L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I+V I+D+ EYE+ E F I LGEP +++ GI + E T E + ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ED D+ EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA ++ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NFTPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHTDEPEDFASKVFFDPCSYQCLENCGAVLLTVVRKGGD--ISKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRVEEEQLAEGMLPAI--LNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDAYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMER-GISALLLSPEVTDRKLTVEEE--------EAKRIAEMGKPVLGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSA--GGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAMQGQEFHVSAGTLAFSVTLFTIFAFVCLSVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 927
BLAST of slc8a-1 vs. Ensembl Mouse
Match: Slc8a1 (solute carrier family 8 (sodium/calcium exchanger), member 1 [Source:MGI Symbol;Acc:MGI:107956]) HSP 1 Score: 830.091 bits (2143), Expect = 0.000e+0 Identity = 477/935 (51.02%), Postives = 630/935 (67.38%), Query Frame = 2
Query: 410 QCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH-----ELHCNHSLEDAHLDG--------DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNN-QKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRA---VTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILV----KKPGIGKSNIP--KEFTGFNH--------VSEVKTHSDQLVSQSSE---IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
+ E N E CKKG++LP+W+P S GDKIARA VYFV+++Y+FLGVSIIADRFM+SIEVITS+E+++ ++K NGE VRIWNETVSNLTLMALGSSAPEILLSVIE+CG NF AGDLGP TIVGSAAFN+FIII CVYV+PDGE R+IKHL VF +TA+WS+FAY WLY+I++ SP V++VWE LLTFFFF + V+ A+VAD ++ K++ +RY + +E GD E+ + + ++H+D + E + E+ R + +++E++ K+P + + L E A +VL++ KSRAFYR+QATR +TG+GN++K+ ++ R + ++ ++ EN+ KIFF+ G Y +EN GT + + R G D T + V++ TEDGTA AG DY T G V+F+ GE QK I + IIDDDIFE DE+F ++L + R V++DG S N + G P ATI + DDDHAGIF FEE T V+ES G E+KV R+SGARG V++PY++ TA GG D+ + LEF ND+ I V +IDD EYEK++ F IE+GEP LV KK G + P ++ +H +SE L S+ E I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW+EQF+EAITVS + +D D+ EEKLPSC DYVMHFLT+FWKVLFAFVPPT+Y GW F V I++IG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH G F+V G+L FSVT+F IFA + +L RR +GGELGGPR K+ T+ FV LW++Y+ SSLE YCHIKGF
Sbjct: 35 EAETGGNETTECTGSYYCKKGVILPIWEP-QDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGD---LSTTVFVDFRTEDGTANAGSDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILES-NHASSIACLG----SPSTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKGGFTLTGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSA--GEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF 958
BLAST of slc8a-1 vs. Ensembl Mouse
Match: Slc8a1 (solute carrier family 8 (sodium/calcium exchanger), member 1 [Source:MGI Symbol;Acc:MGI:107956]) HSP 1 Score: 826.624 bits (2134), Expect = 0.000e+0 Identity = 480/948 (50.63%), Postives = 632/948 (66.67%), Query Frame = 2
Query: 410 QCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH-----ELHCNHSLEDAHLDG--------DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNN-QKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRA---VTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVK---KPGIGKSNIPKEFT----------------GFNH--------VSEVKTHSDQLVSQSSE---IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
+ E N E CKKG++LP+W+P S GDKIARA VYFV+++Y+FLGVSIIADRFM+SIEVITS+E+++ ++K NGE VRIWNETVSNLTLMALGSSAPEILLSVIE+CG NF AGDLGP TIVGSAAFN+FIII CVYV+PDGE R+IKHL VF +TA+WS+FAY WLY+I++ SP V++VWE LLTFFFF + V+ A+VAD ++ K++ +RY + +E GD E+ + + ++H+D + E + E+ R + +++E++ K+P + + L E A +VL++ KSRAFYR+QATR +TG+GN++K+ ++ R + ++ ++ EN+ KIFF+ G Y +EN GT + + R G D T + V++ TEDGTA AG DY T G V+F+ GE QK I + IIDDDIFE DE+F ++L + R V++DG S N + G P ATI + DDDHAGIF FEE T V+ES G E+KV R+SGARG V++PY++ TA GG D+ + LEF ND+ I V +IDD EYEK++ F IE+GEP LV+ K G G SN+ FT +H +SE L S+ E I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW+EQF+EAITVS + +D D+ EEKLPSC DYVMHFLT+FWKVLFAFVPPT+Y GW F V I++IG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH G F+V G+L FSVT+F IFA + +L RR +GGELGGPR K+ T+ FV LW++Y+ SSLE YCHIKGF
Sbjct: 35 EAETGGNETTECTGSYYCKKGVILPIWEP-QDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGD---LSTTVFVDFRTEDGTANAGSDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILES-NHASSIACLG----SPSTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKG-GLSNVLCGFTLTGKEMYGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSA--GEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF 970
BLAST of slc8a-1 vs. Ensembl Mouse
Match: Slc8a3 (solute carrier family 8 (sodium/calcium exchanger), member 3 [Source:MGI Symbol;Acc:MGI:107976]) HSP 1 Score: 825.469 bits (2131), Expect = 0.000e+0 Identity = 470/906 (51.88%), Postives = 621/906 (68.54%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQ---DGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG N T LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D I+KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R + +G +I L + L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I + +IDD YEK++ + IE+ P +V ++ K V++ K ++ ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ED D+ EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA ++ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NFTPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHTDEPEDFASKVFFDPCSYQCLENCGAVLLTVVRKGGD--ISKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRVEEEQLAEGMLPAI--LNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDAYGELEFKNDETVKTIHIKVIDDKAYEKNKNYVIEMMGPRMVDM------SVQKALLLSPEVTDRKLTVEE--EEAKRIAEMGKPVLGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSA--GGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAMQGQEFHVSAGTLAFSVTLFTIFAFVCLSVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 928
BLAST of slc8a-1 vs. UniProt/SwissProt
Match: sp|P70549|NAC3_RAT (Sodium/calcium exchanger 3 OS=Rattus norvegicus OX=10116 GN=Slc8a3 PE=1 SV=1) HSP 1 Score: 837.025 bits (2161), Expect = 0.000e+0 Identity = 476/906 (52.54%), Postives = 622/906 (68.65%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRA---VTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF +TA+WSVFAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ +RY + +E G+H + + + ++H LDG NL LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D I+KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R ++G +I L + L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I+V I+D+ EYE+ E F I LGEP +++ GI + E T E + ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA ++ +L RR +GGELGGPR K+ATT FV LW++YV+ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSVFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKRYRTDKHRGIIIETEGEHPKGIEMDGKMMNSHFLDG----NLIPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTASMSEVHTDEPEDFASKVFFDPCSYQCLENCGAVLLTVVRKGGD--ISKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRVEEEQLEEGMTPAI--LNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMER-GISALLLSPEVTDRKLTMEEE--------EAKRIAEMGKPVLGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEEEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAMQGQEFHVSAGTLAFSVTLFTIFAFVCLSVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYVLFATLEAYCYIKGF 927
BLAST of slc8a-1 vs. UniProt/SwissProt
Match: sp|P57103|NAC3_HUMAN (Sodium/calcium exchanger 3 OS=Homo sapiens OX=9606 GN=SLC8A3 PE=1 SV=2) HSP 1 Score: 830.861 bits (2145), Expect = 0.000e+0 Identity = 475/907 (52.37%), Postives = 622/907 (68.58%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPR---AVTQDGKKVSI-NQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF ITA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG NL LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D ++KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R ++G +I N L L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I+V I+D+ EYE+ E F I LGEP +++ GI + + T E + ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ++ ED EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA I+ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFISKVFFDPCSYQCLENCGAVLLTVVRKGGD--MSKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAV---LASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMER-GISALLLSPDVTDRKLTMEEE--------EAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDE--SGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 927
BLAST of slc8a-1 vs. UniProt/SwissProt
Match: sp|S4R2P9|NAC3_MOUSE (Sodium/calcium exchanger 3 OS=Mus musculus OX=10090 GN=Slc8a3 PE=1 SV=1) HSP 1 Score: 825.469 bits (2131), Expect = 0.000e+0 Identity = 470/906 (51.88%), Postives = 621/906 (68.54%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHE--LHCNHSLEDAH-LDGDKKENLTELE-----KTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQ---DGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
N +C +D CK+G++LP+W P S+GDKIAR VYFV+L+Y+FLGVSIIADRFMASIEVITS+ER+V ++K NGE T +R+WNETVSNLTLMALGSSAPEILLS+IE+CG F AGDLGP TIVGSAAFN+FIIIG CVYVIPDGE R+IKHL VF +TA+WS+FAYIWLY+I+A FSP V+QVWE LLT FFF + VL A+VAD ++ K++ ++Y + +E GDH + + + ++H LDG N T LE ++R + I ++++++ K+P D L E A L+ KSRAFYR+QATR +TG+GN++KK E+ + + ++ E E+ K+FFDP Y +EN G + V R G D I+KTM V+Y TEDG+A AG DY T G V+ + GE QK + IIDDDIFE DEHFF+ L + R + +G +I L + L P +AT+ +LDDDHAGIF FE V+ES G E+KV R+SGARG V+VP+R+ TA GG D+ + LEF ND+T I + +IDD YEK++ + IE+ P +V ++ K V++ K ++ ++ I +MGKP LG+ +++VII+ES EFK VD L++ L+ +GT SW++QF+EAITVS ED D+ EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F V I++IG LTA+IGDLAS FGCTIG+ ++VTA+ FVA GTS+PDTFASK AA+ D AD+S+GNVTGSNAVNVFLGIGLAWS+AA+Y +G F V +G+L FSVT+F IFA ++ +L RR +GGELGGPR K+ATT FV LW++Y++ ++LE YC+IKGF
Sbjct: 45 NESCSGSSD--CKEGVILPIWYP-ENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDG----NFTPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKTSSMSEVHTDEPEDFASKVFFDPCSYQCLENCGAVLLTVVRKGGD--ISKTMY-VDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRVEEEQLAEGMLPAI--LNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDAYGELEFKNDETVKTIHIKVIDDKAYEKNKNYVIEMMGPRMVDM------SVQKALLLSPEVTDRKLTVEE--EEAKRIAEMGKPVLGEHPKLEVIIEESYEFKSTVDKLIKKTNLALVVGTHSWRDQFMEAITVSA--GGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAMQGQEFHVSAGTLAFSVTLFTIFAFVCLSVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 928
BLAST of slc8a-1 vs. UniProt/SwissProt
Match: sp|Q8K596|NAC2_MOUSE (Sodium/calcium exchanger 2 OS=Mus musculus OX=10090 GN=Slc8a2 PE=1 SV=1) HSP 1 Score: 822.002 bits (2122), Expect = 0.000e+0 Identity = 450/899 (50.06%), Postives = 615/899 (68.41%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKS---YALEGD--HELHCNHSLEDAHLDGD------KKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGV---ELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSE----IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
C+ G++LP+W+P S+GDK+ARA VYFV+++Y+FLGVSIIADRFMASIEVITSKE+++ + K NGE VRIWNETVSNLTLMALGSSAPEILL+VIE+CG NF+AG+LGPGTIVGSAAFN+F++I CVYVIP GE R+IKHL VF +TASWS+FAY+WLYLI+A FSP V+QVWEALLT FF + V+ A++AD ++ K++ +RY R + +S EGD + + + + G+ EL+ +R + I+++++++ K+P+ D + L A+ L KSRAFYR+QATR +TG+GNV+++ + ++++ +IFF+P Y +EN G+ + V G + + V+Y TEDG+A AG DY + G ++F+ GE QK + I IIDDDIFE DEHFF+ L + R G + E + G L+ P +AT+ +LDDDHAGIF+F++ V+E G +++V RSSGARG V +PYR+ TA GG Y + LEF +D+T ++V I+DD EYEK + F IELG+P +K+ G + + + + D+ ++ E I +MGKP LG+ ++VII+ES +FK+ VD L++ L+ IGT SW+EQF+EA+TVS G+ + ED D EE+LPSC DYVMHFLT+FWKVLFA VPPT+Y GW F VCI+VIG LTA+IGDLAS FGCT+G+ ++V A+ FVA+GTS+PDTFASKVAA+ D AD+S+GNVTGSNAVNVFLG+G+AWS+AAVY +G F V++G+L FSVT+F +FA IA +L RR ++GGELGGPR K+ATT F+GLW +Y++ SSLE YCHI+GF
Sbjct: 49 CQPGVLLPVWEP-EDPSLGDKVARAVVYFVAMVYMFLGVSIIADRFMASIEVITSKEKEITITKANGETSVGTVRIWNETVSNLTLMALGSSAPEILLTVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVCVYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLIFFPVCVVFAWMADKRLLFYKYVYKRY-RTDPRSGIIIGAEGDPPKSIELDGTFVGTEVPGELGALGTGPAEARELDASRREVIQILKDLKQKHPDKDLEQLMGIAKYYALLHQQKSRAFYRIQATRLMTGAGNVLRRHAADAARRPGATDGAPDDEDDGASRIFFEPSLYHCLENCGSVLLSVACQGGE---GNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKDLRIGIIDDDIFEEDEHFFVRLLNLRVGDAQG-------MFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGTVDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEEYEKKDNFFIELGQPQWLKR-------------GISALLLNQGNGDKKITAEQEEAQRIAEMGKPVLGENNRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFIEAVTVSAGDEE-EDEDGPREERLPSCFDYVMHFLTVFWKVLFACVPPTEYCNGWACFGVCILVIGVLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQGRPFEVRAGTLAFSVTLFTVFAFVCIAVLLYRRRPQIGGELGGPRGPKLATTALFLGLWFLYILFSSLEAYCHIRGF 921
BLAST of slc8a-1 vs. UniProt/SwissProt
Match: sp|P70414|NAC1_MOUSE (Sodium/calcium exchanger 1 OS=Mus musculus OX=10090 GN=Slc8a1 PE=1 SV=1) HSP 1 Score: 821.617 bits (2121), Expect = 0.000e+0 Identity = 475/948 (50.11%), Postives = 628/948 (66.24%), Query Frame = 2
Query: 410 QCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDH-----ELHCNHSLEDAHLDG--------DKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENNN-QKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRA---VTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGF-------------------NH--------VSEVKTHSDQLVSQSSE---IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
+ E N E CKKG++LP+W+P S GDKIARA VYFV+++Y+FLGVSIIADRFM+SIEVITS+E+++ ++K NGE VRIWNETVSNLTLMALGSSAPEILLSVIE+CG NF AGDLGP TIVGSAAFN+FIII CVYV+PDGE R+IKHL VF +TA+WS+FAY WLY+I++ SP V++VWE LLTFFFF + V+ A+VAD ++ K++ +RY + +E GD E+ + + ++H+D + E + E+ R + +++E++ K+P + + L E A +VL++ KSRAFYR+QATR +TG+GN++K+ ++ R + ++ ++ EN+ KIFF+ G Y +EN GT + + R G D T + V++ TEDGTA A DY T G V+F+ GE QK I + IIDDDIFE DE+F ++L + R V++DG S N + G P ATI + DDDHAGIF FEE T V+ES G E+KV R+SGARG V++PY++ TA GG D+ + EF ND+ I V +IDD EYEK++ F IE+GEP LV+ K+ + E GF +H +SE L S+ E I +MG+P LG+ +++VII+ES EFK VD L++ L+ +GT+SW+EQF+EAITVS + +D D+ EEKLPSC DYVMHFLT+FWKVLFAFVPPT+Y GW F V I++IG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAA D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH G F+V G+L FSVT+F IFA + +L RR +GGELGGPR K+ T+ FV LW++Y+ SSLE YCHIKGF
Sbjct: 35 EAETGGNETTECTGSYYCKKGVILPIWEP-QDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGD---LSTTVFVDFRTEDGTANAASDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILES-NHASSIACLG----SPSTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGEPEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSE-KKALLLNELGGFTLTGKEMYGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIQESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSA--GEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF 970
BLAST of slc8a-1 vs. TrEMBL
Match: A0A0H3YEY7 (Slc8a-1 OS=Schmidtea mediterranea OX=79327 GN=slc8a-1 PE=2 SV=1) HSP 1 Score: 1805.42 bits (4675), Expect = 0.000e+0 Identity = 917/917 (100.00%), Postives = 917/917 (100.00%), Query Frame = 2
Query: 350 MRGNLLFGSCIVVIEFLSWIQCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
MRGNLLFGSCIVVIEFLSWIQCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEALLTFFFFFLTVLTAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPIEISIIDDDIFEADEHFFINLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF
Sbjct: 1 MRGNLLFGSCIVVIEFLSWIQCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEALLTFFFFFLTVLTAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPIEISIIDDDIFEADEHFFINLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 917
BLAST of slc8a-1 vs. TrEMBL
Match: A0A075A220 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_00721 PE=3 SV=1) HSP 1 Score: 1009.21 bits (2608), Expect = 0.000e+0 Identity = 545/914 (59.63%), Postives = 674/914 (73.74%), Query Frame = 2
Query: 416 EPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTAT-GGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVS------------------QSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
+ L NG C S T+C GI++P W+P GLS+GDK+ARA +YF L+YLFLGVSIIADRFMA+IEVITSKE++V VRKKNGE+QTI VRIWN TVSNLTLMALGSSAPEILLSVIEI G NFEAGDLGPGTIVGSAAFNLF+IIG CV VIP+GEVRRIKHLSVF ITASWS+FAY+WLYLIIA FSP V+++WEALLTF FF + V+ AY+ADTKI K ++ R + +++ D E + NH+ E ++ ++E E+TR++Y++ I+EIR KNPNID K LEE AQ++VL++ PKSRAFYRMQATR LTGSGNVIKK+K+ERR+S D ++ + + Q+IFF+PGHYTVMENVGTF + V R G D ++ V Y T DGTA A +DY+ SGV++F++GE K I+IIDDDIFE DEHF + L P V N E L+EP ATIMVLDDDH+G+F+FE+ T V ESC AE+KV R SG RG+V VPY++ +A GG DY + YLEF NDQTEA I+V ++DDN+YEK E+F ++LGEP+LV K + ++ FT N + + +++ S S + D GKPRLG+ IKV I ES EFK+ VD L++ G+ + +GTSSWKEQFVEA+TVS G D E + DL EEKLPSC+DYVMHFLT+FWKVLFAFVPPTDY GGW F VCI+VIG LTA+IGD+AS FGC+IG+T+AVTAITFVA+GTS PDTFASKVAAI D ADSS+GNVTGSNAVNVFLGIG+AWSIAA+YH +G+ F V+ GSLGFSVTVFCIFAL AI ++LRR VGGELGGP+ +K + ++F+ LW+ Y+IL+ LENYCHI+GF
Sbjct: 26 DKLINGTCPSSKKTACVDGILIPKWEPSTGLSVGDKLARATIYFACLLYLFLGVSIIADRFMAAIEVITSKEKEVTVRKKNGEVQTIYVRIWNTTVSNLTLMALGSSAPEILLSVIEIIGKNFEAGDLGPGTIVGSAAFNLFVIIGICVLVIPEGEVRRIKHLSVFFITASWSIFAYLWLYLIIAAFSPGVVEIWEALLTFIFFPIIVICAYIADTKI-FFKKFLKKKFRAAGRLKSIDIDAE-YPNHTEEVTYVPESDDSQVSEFERTRLNYVDAIKEIRKKNPNIDMKQLEEMAQLDVLSKGPKSRAFYRMQATRQLTGSGNVIKKAKVERRMSSDDQRMESESYAPHVQRIFFNPGHYTVMENVGTFPITVSRVGGD---LDAVVSVNYSTVDGTAVADEDYVPVSGVLVFKAGETHKQFSITIIDDDIFEEDEHFTVILTDPTVVHS-------NTFVEP-----LLVEPTKATIMVLDDDHSGVFHFEQQATSVPESCEYAELKVLRDSGCRGIVRVPYQTIEGSAKGGGKDYEDAIGYLEFQNDQTEATIRVRVVDDNDYEKSEFFFVQLGEPLLVDKD--AQQSLLSRFT--NRRPTIPSTPEKVASPDAGKQLALPETQETGRRTSQGLIDTGKPRLGEWSRIKVTIVESNEFKNTVDRLVKQGKWALVVGTSSWKEQFVEAVTVSAG-GDGEGA-DLEEEKLPSCMDYVMHFLTVFWKVLFAFVPPTDYGGGWWCFSVCILVIGVLTAIIGDMASAFGCSIGLTDAVTAITFVALGTSPPDTFASKVAAIGDSDADSSIGNVTGSNAVNVFLGIGIAWSIAAIYHAIQGTQFYVQPGSLGFSVTVFCIFALAAITVIVLRRRPSVGGELGGPKTVKYLSGLFFITLWLCYIILAGLENYCHIEGF 916
BLAST of slc8a-1 vs. TrEMBL
Match: G7YEK8 (Solute carrier family 8 OS=Clonorchis sinensis OX=79923 GN=CLF_106026 PE=3 SV=1) HSP 1 Score: 1005.36 bits (2598), Expect = 0.000e+0 Identity = 548/929 (58.99%), Postives = 676/929 (72.77%), Query Frame = 2
Query: 422 LKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTAT-GGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILV-----------KKPGI------GKSNIPKEFTGFNHVSEVKTHSDQLVS------------------QSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
L NG C S T+C G+++P W+P GLS+GDK+ARA +YF L+YLFLGVSIIADRFMA+IEVITSKE++V VRKKNGE+QTI VRIWN TVSNLTLMALGSSAPEILLSVIEI G NFEAGDLGPGTIVGSAAFNLF+IIG CV VIP+GEVRRIKHLSVF ITASWS+FAY+WLYLIIA FSP V+++WEALLTF FF + V+ AY+ADTKI K ++ R + +++ D E + NH+ E ++ + ++E E+TR++Y++ I+EIR KNPNID K LEE AQ++VL++ PKSRAFYRMQATR LTGSGNVIKK+K+ERR+S D ++ + + Q+IFF+PGHYTVMENVGTF + V R G D ++ V Y T DGTA A +DY+ SGV++F++GE K I+IIDDDIFE DEHF + L P V N E L+EP ATIMVLDDDH+G+F+FE+ T V ESC AE+KV R SG RG+V VPY++ +A GG DY + YLEF NDQTEA I+V ++DDN+YEK E+F ++LGEP+LV KK I + +I FT N + +++ S S + D GKPRLG+ IKV I ES EFK+ VD L++ G+ + +GTSSWKEQFVEA+TVS G D E + DL EEKLPSC+DYVMHFLT+FWKVLFAFVPPTDY GGW F VCI+VIG LTA+IGD+AS FGC+IG+T+AVTAITFVA+GTSLPDTFASKVAAI D ADSS+GNVTGSNAVNVFLGIG+AWSIAA+YH +G+ F V+ GSLGFSVTVFCIFAL AI ++LRR VGGELGGP+ +K + ++F+ LW+ Y+IL+ LENYCHI+GF
Sbjct: 28 LINGTCPSSKKTACVDGVLIPKWEPSTGLSVGDKLARATIYFACLLYLFLGVSIIADRFMAAIEVITSKEKEVTVRKKNGEVQTIYVRIWNTTVSNLTLMALGSSAPEILLSVIEIIGKNFEAGDLGPGTIVGSAAFNLFVIIGICVLVIPEGEVRRIKHLSVFFITASWSIFAYLWLYLIIAAFSPGVVEIWEALLTFIFFPIIVICAYIADTKI-FFKKFLKKKFRAAGRLKSIDIDAE-YPNHTEEVTYIPESDENQVSEFERTRLNYVDAIKEIRKKNPNIDMKQLEEMAQLDVLSKGPKSRAFYRMQATRQLTGSGNVIKKAKVERRMSSDDQRMESESYAPHVQRIFFNPGHYTVMENVGTFPITVSRVGGD---LDAVVSVNYSTVDGTAVADEDYVPVSGVLVFKAGETHKQFSITIIDDDIFEEDEHFTVILTDPTVVHS-------NTFLEP-----LLVEPTKATIMVLDDDHSGVFHFEQQATSVPESCEYAELKVLRDSGCRGIVRVPYQTIEGSAKGGGKDYEDTIGYLEFQNDQTEATIRVRVVDDNDYEKSEFFFVQLGEPLLVDKDEEHEQRFMKKMNISMTESEAQQSILSRFT--NRRPTIPNTPEKVASPENGKQLALPETQESGRRTSQGLIDTGKPRLGEWSRIKVTIVESNEFKNTVDRLVKQGKWALVVGTSSWKEQFVEAVTVSAG-GDGEGA-DLEEEKLPSCMDYVMHFLTVFWKVLFAFVPPTDYGGGWWCFSVCILVIGVLTAIIGDMASAFGCSIGLTDAVTAITFVALGTSLPDTFASKVAAIGDSDADSSIGNVTGSNAVNVFLGIGIAWSIAAIYHAIQGTQFYVQPGSLGFSVTVFCIFALAAITVIVLRRRPSVGGELGGPKTVKYLSGLFFITLWLCYIILAGLENYCHIEGF 935
BLAST of slc8a-1 vs. TrEMBL
Match: A0A4E0RE08 (Sodium calcium exchanger OS=Fasciola hepatica OX=6192 GN=D915_003293 PE=3 SV=1) HSP 1 Score: 1005.36 bits (2598), Expect = 0.000e+0 Identity = 553/918 (60.24%), Postives = 679/918 (73.97%), Query Frame = 2
Query: 428 NGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRR-----YLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTAT-GGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKK---------------------PGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
NG C S T C GI++P W+P GLS GDK ARA VYF LMYLFLGVSIIADRFMA+IEVITS+E++V ++KKNGE+Q I VRIWNETVSNLTLMALGSSAPEILLSVIEICG +FEAGDLGPGTIVGSAAFNLF+IIG CV V+P+G++RRIKHLSVFLITASWSVFAY+W+YLI+A FSP V+++WEAL+TF FF + VL AYVADTKIF KKFLK+R YL+K V + +SLE +++E EK R+DY+E IREIR +NPNID K LEE AQ+EVLN+ PKSRAFYRMQATR LTGSGNVIKK+K+ERR+S+D +L + ++ Q+ FF+PGHYTVMENVGTF+V V R G D ++ V+Y T DGTAT+G+DY+ SG ++F+SGE K I ++IIDDDIFE DEHF I L + + + G + L++P +ATIMVLDDDH+GIF+FE V+ESC AE+KV R SG RGVV +PY++ TA GG DY + +LEF N+QTE +I+V I+DDN+YEK E+F ++LGEP+LV K P + K +P + G +EVK S + + GKPRLG+ IKV I ES EFK+ VD L++ G+ + +GTSSWKEQFVEAITVS G + D+ EEKLPSC+DYVMHFLT+FWKVLFAFVPPTDY GGW+ F VCI+VIG LTAVIGD+AS FGC++G+T+AVTAITFVA+GTSLPDTFASKVAAI D ADSS+GNVTGSNAVNVFLGIG+AWSIAA++H +G+ F VK GSLGFSVTVFCIFAL AI +LLRR+ VGGELGGP+ +K + +F+GLW++Y+IL+ LENYCHI+GF
Sbjct: 29 NGTCLSSTKTQCVDGILIPKWEPSEGLSAGDKAARATVYFACLMYLFLGVSIIADRFMAAIEVITSQEKEVKIKKKNGEVQIIYVRIWNETVSNLTLMALGSSAPEILLSVIEICGKHFEAGDLGPGTIVGSAAFNLFVIIGLCVMVVPNGQIRRIKHLSVFLITASWSVFAYLWMYLILAVFSPGVVELWEALITFIFFPVIVLCAYVADTKIFFKKFLKKRYKAAGYLKK-VGKENELEKLKEEVTYSLE------ADDNSVSEFEKHRLDYVEAIREIRKRNPNIDMKQLEEMAQMEVLNKGPKSRAFYRMQATRQLTGSGNVIKKAKVERRMSEDSCRLEGESYPSHVQRFFFNPGHYTVMENVGTFSVTVSRIGGD---LNAVVSVDYETVDGTATSGEDYVPASGTLVFRSGESYKQIPVTIIDDDIFEEDEHFTIELSNLKVMNSHGPVEPM------------LVDPKVATIMVLDDDHSGIFHFELQTKDVSESCEYAELKVVRDSGCRGVVRLPYQTIEGTAKGGGKDYEDNVGFLEFQNNQTEDYIRVRIMDDNDYEKHEFFFVQLGEPVLVNKDAQPKLLSRFARRRSTAGSTAPTVEKVAVPDDTNG--KRAEVKDLSSGTTKLPEDFVETGKPRLGEWTRIKVNIVESYEFKNTVDRLVKQGKWALVVGTSSWKEQFVEAITVSAGGDSDPTGDE--EEKLPSCMDYVMHFLTVFWKVLFAFVPPTDYGGGWLCFSVCILVIGVLTAVIGDMASSFGCSVGLTDAVTAITFVALGTSLPDTFASKVAAIGDQYADSSIGNVTGSNAVNVFLGIGVAWSIAAIHHAIQGTQFFVKPGSLGFSVTVFCIFALVAITLILLRRHPAVGGELGGPKTIKYLSGSFFIGLWVIYIILAGLENYCHIEGF 920
BLAST of slc8a-1 vs. TrEMBL
Match: A0A087VYY9 (Sodium calcium exchanger OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000117900 PE=3 SV=1) HSP 1 Score: 945.266 bits (2442), Expect = 0.000e+0 Identity = 514/905 (56.80%), Postives = 668/905 (73.81%), Query Frame = 2
Query: 425 KNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAH--LDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATG-GTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPG-------IGKSNIPKEFTGFNHVSEV-KTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRV-GGELGGPR-HLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++G C S + SCK G++LP+W+P +S+ RA VYF+SLMY FLGVSIIADRFMA+IEVITS+E++V V+ K+GE+Q I+VRIWNETVSNLTLMALGSSAPEILLS+IEICG+NFEAG+LGPGTIVGSAAFNLF+IIG C+ VIP+GE RRIKH VF++T+ WSVFAY+WLY II+ S +++ WEA LTF FF +TV+TAY+AD K+F +KFLK+RY + Y ++ ++ N ++ + + E EKTR++YIE I+EIR KNP IDPK LEE AQIEVLN+ PKSRA+YR+QATR LTGSGNVI KSKLER+LS ++ + + Q+++F+PGHYTVMENVG+F + + R G D + + ++Y TEDGTA A +DY T+G ++F+S E K I I+IIDDD+FE DEHF + L + R + G LT + +L++P +AT+MVLDDDH+G+F+F ++ESC AE V RSSGARG V VP+++ +A G G DY + ++EF+NDQTE I+V I+DDN+YEK EYF IELG+P LV+K G + + P + V +V T +D++ +E D G PRLG ++V IKES E K+ VD L++HG+ +GTSSWKEQFV+AITV+ G++D ++ E+K+PSC DYVMHFLT+FWKVLFAFVPPT+Y GGWV F V I+VIG LTA+IGDLAS FGCT+G+T+AVT+ TFVA+GTSLPDTFASKVAAI D ADSS+ NVTGSNAVNVFLGIG+AW+IAA+ H+ +GSTF V +GSLGFSVT+FCIFAL AIA ++LRR + GGELGGPR +K A+ I+F+ LW++YV+LSSLENYC+I GF
Sbjct: 27 EDGKCPSTANISCKDGLLLPVWRPKDNISVARIAGRAIVYFLSLMYCFLGVSIIADRFMAAIEVITSQEKEVRVKSKSGEVQVISVRIWNETVSNLTLMALGSSAPEILLSIIEICGTNFEAGELGPGTIVGSAAFNLFVIIGICIAVIPNGETRRIKHFGVFVVTSIWSVFAYLWLYFIISVTSKGIVEFWEAFLTFLFFPITVITAYIADIKLFQRKFLKKRYKARRKAKYMIKNASDIEANGKFANSEPVSESSEGSLEEEYEKTRLEYIETIKEIRKKNPQIDPKALEELAQIEVLNKGPKSRAYYRIQATRQLTGSGNVITKSKLERKLSIQQTEV-TELYAPDVQQLYFNPGHYTVMENVGSFQITISRKGGD---LRDEVAIDYATEDGTAVANEDYEPTNGTLVFRSNEQHKQISITIIDDDVFEEDEHFDVRLSNLRVIHTSG-------LTSE----WKLVDPVVATVMVLDDDHSGVFHFASESVDISESCEVAEFTVVRSSGARGCVYVPFKTMDGSAKGNGKDYSDTSGFVEFLNDQTEGVIRVPIVDDNDYEKSEYFFIELGQPTLVEKEGAHSFFSMMSEKLFPDTLKRRSLVRKVDPTKADEVTD--TEGLDPGLPRLGQYARLRVNIKESTELKNTVDRLVKHGKWVLLLGTSSWKEQFVDAITVNAGDDDDLEAIAEGEKKMPSCTDYVMHFLTVFWKVLFAFVPPTEYAGGWVCFVVSIIVIGFLTAIIGDLASAFGCTVGLTDAVTSTTFVALGTSLPDTFASKVAAIGDKYADSSICNVTGSNAVNVFLGIGVAWTIAAIVHWVRGSTFVVPAGSLGFSVTIFCIFALFAIALLVLRRKPSLGGGELGGPRASIKWASAIFFLLLWLIYVLLSSLENYCYIVGF 914
BLAST of slc8a-1 vs. Ensembl Cavefish
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:103029712]) HSP 1 Score: 848.966 bits (2192), Expect = 0.000e+0 Identity = 469/916 (51.20%), Postives = 630/916 (68.78%), Query Frame = 2
Query: 425 KNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHELHCNHSLE------DAH----LDGDKKENLTEL--EKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENN-NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNH---VSEVKTHSDQLVSQSSE----IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++G C CK+G++LPLW P S DK+ARA +YFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIPDG+ R++KHL VF +TA+WS+FAY WLYLI+A SP V++VWE LLT FFF + V+ A+VAD ++ K++ +RY + +E G+ EL +E ++H LDG ++ E+ E+ R + ++++++ K+P + + L E A +VL++ KSRAFYR QATR +TG+GN++KK ++ R + +L + +N+ + KIFFDPG Y +EN G+ + V R G D + I V Y TEDGTA AG DY + GV++F GE +K I I IIDDDIFE DEHF ++L + + +++ S ++ G+ L P AT+ + DDDHAGIF FEE V+ES G E+KV R+SGARG V+VPY++ TA GG D+ + LEF ND+ +++NIIDD EYEK++ F +ELGEP +++ ++ ++ G ++ + + D +SQ + I +MG+P LGD ++V+I+ES EFK VD L++ L+ +GT+SW+EQFVEAITV+ G +D E+ SEEKLPSC DYVMHFLT+FWK+LFAFVPPTDY GW F V I +IG LTAVIGDLAS FGCT+G+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+ +GNVTGSNAVNVFLGIG+AWSIAA+YH + G FRV+ G+L FSVT+F IFA IA ++ RR +GGELGGPR K T+ F LW++Y++LSSLE YC IKGF
Sbjct: 54 ESGTCS--GSYECKEGVILPLWTP-ENPSFPDKLARATIYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGDHRKVKHLRVFFVTAAWSIFAYTWLYLILAVISPGVVEVWEGLLTLFFFPICVVFAWVADRRLLFYKYVNKRYRVGKQRGMIIETEGEPELQSKADIEMDGQMLNSHGEDFLDGAVNTDIKEMDEEEARREMARILKDLKQKHPEKEMEQLIELANYQVLSQQQKSRAFYRCQATRLMTGAGNILKKHAADQARKAICTHELRTEVSDNDFSSKIFFDPGTYQCLENCGSVALNVVRRGGD---LTSTISVSYRTEDGTANAGSDYEFSEGVIVFNPGETEKEIRIEIIDDDIFEEDEHFLVHLSNIQVLSESRNNGSPVLNHVDSLAGLGL--PSTATVTIFDDDHAGIFAFEEQMMHVSESIGIMEVKVVRTSGARGAVVVPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTLQINIIDDEEYEKNKNFFMELGEPRMMEMSERKGGDVYRKVQGRDNPVPSTIINLAEDISLSQKEQEERRIAEMGRPTLGDNTRLEVVIEESYEFKSTVDKLIKKTNLALLVGTNSWREQFVEAITVNSGGDDDEEC---SEEKLPSCFDYVMHFLTVFWKILFAFVPPTDYWNGWACFVVSISMIGLLTAVIGDLASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADACIGNVTGSNAVNVFLGIGVAWSIAAIYHQWNGQYFRVQPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRTAKRITSSLFFSLWLLYIVLSSLEAYCIIKGF 958
BLAST of slc8a-1 vs. Ensembl Cavefish
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:103029712]) HSP 1 Score: 846.655 bits (2186), Expect = 0.000e+0 Identity = 471/913 (51.59%), Postives = 625/913 (68.46%), Query Frame = 2
Query: 425 KNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHELHCNHSLE------DAH----LDGDKKENLTEL--EKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENN-NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSE----IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++G C CK+G++LPLW P S DK+ARA +YFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIPDG+ R++KHL VF +TA+WS+FAY WLYLI+A SP V++VWE LLT FFF + V+ A+VAD ++ K++ +RY + +E G+ EL +E ++H LDG ++ E+ E+ R + ++++++ K+P + + L E A +VL++ KSRAFYR QATR +TG+GN++KK ++ R + +L + +N+ + KIFFDPG Y +EN G+ + V R G D + I V Y TEDGTA AG DY + GV++F GE +K I I IIDDDIFE DEHF ++L + + +++ S ++ G+ L P AT+ + DDDHAGIF FEE V+ES G E+KV R+SGARG V+VPY++ TA GG D+ + LEF ND+ +++NIIDD EYEK++ F +ELGEP +++ +SE K D +SQ + I +MG+P LGD ++V+I+ES EFK VD L++ L+ +GT+SW+EQFVEAITV+ G +D E+ SEEKLPSC DYVMHFLT+FWK+LFAFVPPTDY GW F V I +IG LTAVIGDLAS FGCT+G+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+ +GNVTGSNAVNVFLGIG+AWSIAA+YH + G FRV+ G+L FSVT+F IFA IA ++ RR +GGELGGPR K T+ F LW++Y++LSSLE YC IKGF
Sbjct: 65 ESGTCS--GSYECKEGVILPLWTP-ENPSFPDKLARATIYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGDHRKVKHLRVFFVTAAWSIFAYTWLYLILAVISPGVVEVWEGLLTLFFFPICVVFAWVADRRLLFYKYVNKRYRVGKQRGMIIETEGEPELQSKADIEMDGQMLNSHGEDFLDGAVNTDIKEMDEEEARREMARILKDLKQKHPEKEMEQLIELANYQVLSQQQKSRAFYRCQATRLMTGAGNILKKHAADQARKAICTHELRTEVSDNDFSSKIFFDPGTYQCLENCGSVALNVVRRGGD---LTSTISVSYRTEDGTANAGSDYEFSEGVIVFNPGETEKEIRIEIIDDDIFEEDEHFLVHLSNIQVLSESRNNGSPVLNHVDSLAGLGL--PSTATVTIFDDDHAGIFAFEEQMMHVSESIGIMEVKVVRTSGARGAVVVPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTLQINIIDDEEYEKNKNFFMELGEPRMME------------------MSERK--EDISLSQKEQEERRIAEMGRPTLGDNTRLEVVIEESYEFKSTVDKLIKKTNLALLVGTNSWREQFVEAITVNSGGDDDEEC---SEEKLPSCFDYVMHFLTVFWKILFAFVPPTDYWNGWACFVVSISMIGLLTAVIGDLASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADACIGNVTGSNAVNVFLGIGVAWSIAAIYHQWNGQYFRVQPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRTAKRITSSLFFSLWLLYIVLSSLEAYCIIKGF 946
BLAST of slc8a-1 vs. Ensembl Cavefish
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:103029712]) HSP 1 Score: 843.188 bits (2177), Expect = 0.000e+0 Identity = 472/935 (50.48%), Postives = 630/935 (67.38%), Query Frame = 2
Query: 425 KNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHELHCNHSLE------DAH----LDGDKKENLTEL--EKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENN-NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEP----------ILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVS----------------QSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++G C CK+G++LPLW P S DK+ARA +YFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIPDG+ R++KHL VF +TA+WS+FAY WLYLI+A SP V++VWE LLT FFF + V+ A+VAD ++ K++ +RY + +E G+ EL +E ++H LDG ++ E+ E+ R + ++++++ K+P + + L E A +VL++ KSRAFYR QATR +TG+GN++KK ++ R + +L + +N+ + KIFFDPG Y +EN G+ + V R G D + I V Y TEDGTA AG DY + GV++F GE +K I I IIDDDIFE DEHF ++L + + +++ S ++ G+ L P AT+ + DDDHAGIF FEE V+ES G E+KV R+SGARG V+VPY++ TA GG D+ + LEF ND+ +++NIIDD EYEK++ F +ELGEP +L+ + G G K+ G + +V+ + + S + I +MG+P LGD ++V+I+ES EFK VD L++ L+ +GT+SW+EQFVEAITV+ G +D E+ SEEKLPSC DYVMHFLT+FWK+LFAFVPPTDY GW F V I +IG LTAVIGDLAS FGCT+G+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+ +GNVTGSNAVNVFLGIG+AWSIAA+YH + G FRV+ G+L FSVT+F IFA IA ++ RR +GGELGGPR K T+ F LW++Y++LSSLE YC IKGF
Sbjct: 69 ESGTCS--GSYECKEGVILPLWTP-ENPSFPDKLARATIYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGDHRKVKHLRVFFVTAAWSIFAYTWLYLILAVISPGVVEVWEGLLTLFFFPICVVFAWVADRRLLFYKYVNKRYRVGKQRGMIIETEGEPELQSKADIEMDGQMLNSHGEDFLDGAVNTDIKEMDEEEARREMARILKDLKQKHPEKEMEQLIELANYQVLSQQQKSRAFYRCQATRLMTGAGNILKKHAADQARKAICTHELRTEVSDNDFSSKIFFDPGTYQCLENCGSVALNVVRRGGD---LTSTISVSYRTEDGTANAGSDYEFSEGVIVFNPGETEKEIRIEIIDDDIFEEDEHFLVHLSNIQVLSESRNNGSPVLNHVDSLAGLGL--PSTATVTIFDDDHAGIFAFEEQMMHVSESIGIMEVKVVRTSGARGAVVVPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTLQINIIDDEEYEKNKNFFMELGEPRMMEMSERKAVLLHECG-GFVKTDKQLFGRDVYRKVQGRDNPVPSTIINLAEDISLSQKEQEERRIAEMGRPTLGDNTRLEVVIEESYEFKSTVDKLIKKTNLALLVGTNSWREQFVEAITVNSGGDDDEEC---SEEKLPSCFDYVMHFLTVFWKILFAFVPPTDYWNGWACFVVSISMIGLLTAVIGDLASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADACIGNVTGSNAVNVFLGIGVAWSIAAIYHQWNGQYFRVQPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRTAKRITSSLFFSLWLLYIVLSSLEAYCIIKGF 991
BLAST of slc8a-1 vs. Ensembl Cavefish
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:103029712]) HSP 1 Score: 842.417 bits (2175), Expect = 0.000e+0 Identity = 472/935 (50.48%), Postives = 630/935 (67.38%), Query Frame = 2
Query: 425 KNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHELHCNHSLE------DAH----LDGDKKENLTEL--EKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENN-NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEP----------ILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVS----------------QSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++G C CK+G++LPLW P S DK+ARA +YFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIPDG+ R++KHL VF +TA+WS+FAY WLYLI+A SP V++VWE LLT FFF + V+ A+VAD ++ K++ +RY + +E G+ EL +E ++H LDG ++ E+ E+ R + ++++++ K+P + + L E A +VL++ KSRAFYR QATR +TG+GN++KK ++ R + +L + +N+ + KIFFDPG Y +EN G+ + V R G D + I V Y TEDGTA AG DY + GV++F GE +K I I IIDDDIFE DEHF ++L + + +++ S ++ G+ L P AT+ + DDDHAGIF FEE V+ES G E+KV R+SGARG V+VPY++ TA GG D+ + LEF ND+ +++NIIDD EYEK++ F +ELGEP +L+ + G G K+ G + +V+ + + S + I +MG+P LGD ++V+I+ES EFK VD L++ L+ +GT+SW+EQFVEAITV+ G +D E+ SEEKLPSC DYVMHFLT+FWK+LFAFVPPTDY GW F V I +IG LTAVIGDLAS FGCT+G+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+ +GNVTGSNAVNVFLGIG+AWSIAA+YH + G FRV+ G+L FSVT+F IFA IA ++ RR +GGELGGPR K T+ F LW++Y++LSSLE YC IKGF
Sbjct: 54 ESGTCS--GSYECKEGVILPLWTP-ENPSFPDKLARATIYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGDHRKVKHLRVFFVTAAWSIFAYTWLYLILAVISPGVVEVWEGLLTLFFFPICVVFAWVADRRLLFYKYVNKRYRVGKQRGMIIETEGEPELQSKADIEMDGQMLNSHGEDFLDGAVNTDIKEMDEEEARREMARILKDLKQKHPEKEMEQLIELANYQVLSQQQKSRAFYRCQATRLMTGAGNILKKHAADQARKAICTHELRTEVSDNDFSSKIFFDPGTYQCLENCGSVALNVVRRGGD---LTSTISVSYRTEDGTANAGSDYEFSEGVIVFNPGETEKEIRIEIIDDDIFEEDEHFLVHLSNIQVLSESRNNGSPVLNHVDSLAGLGL--PSTATVTIFDDDHAGIFAFEEQMMHVSESIGIMEVKVVRTSGARGAVVVPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTLQINIIDDEEYEKNKNFFMELGEPRMMEMSERKAVLLHECG-GFVKTDKQLFGRDVYRKVQGRDNPVPSTIINLAEDISLSQKEQEERRIAEMGRPTLGDNTRLEVVIEESYEFKSTVDKLIKKTNLALLVGTNSWREQFVEAITVNSGGDDDEEC---SEEKLPSCFDYVMHFLTVFWKILFAFVPPTDYWNGWACFVVSISMIGLLTAVIGDLASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADACIGNVTGSNAVNVFLGIGVAWSIAAIYHQWNGQYFRVQPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRTAKRITSSLFFSLWLLYIVLSSLEAYCIIKGF 976
BLAST of slc8a-1 vs. Ensembl Cavefish
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:103029712]) HSP 1 Score: 835.484 bits (2157), Expect = 0.000e+0 Identity = 467/926 (50.43%), Postives = 624/926 (67.39%), Query Frame = 2
Query: 425 KNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALE--GDHELHCNHSLE------DAH----LDGDKKENLTEL--EKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLER-RLSQDPDKLGLKEKENN-NQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGK-SNIPKEFTGFNHVSEVKTHSDQLVS----------------QSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
++G C CK+G++LPLW P S DK+ARA +YFV L Y+FLGVSIIADRFMASIEVITS+E+++ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG NF+AG+LGP TIVGSAAFN+F+IIG CV VIPDG+ R++KHL VF +TA+WS+FAY WLYLI+A SP V++VWE LLT FFF + V+ A+VAD ++ K++ +RY + +E G+ EL +E ++H LDG ++ E+ E+ R + ++++++ K+P + + L E A +VL++ KSRAFYR QATR +TG+GN++KK ++ R + +L + +N+ + KIFFDPG Y +EN G+ + V R G D + I V Y TEDGTA AG DY + GV++F GE +K I I IIDDDIFE DEHF ++L + + +++ S ++ G+ L P AT+ + DDDHAGIF FEE V+ES G E+KV R+SGARG V+VPY++ TA GG D+ + LEF ND+ IKV I+D +EY+K F+++L EP ++ G K+ G + +V+ + + S + I +MG+P LGD ++V+I+ES EFK VD L++ L+ +GT+SW+EQFVEAITV+ G +D E+ SEEKLPSC DYVMHFLT+FWK+LFAFVPPTDY GW F V I +IG LTAVIGDLAS FGCT+G+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+ +GNVTGSNAVNVFLGIG+AWSIAA+YH + G FRV+ G+L FSVT+F IFA IA ++ RR +GGELGGPR K T+ F LW++Y++LSSLE YC IKGF
Sbjct: 69 ESGTCS--GSYECKEGVILPLWTP-ENPSFPDKLARATIYFVGLFYMFLGVSIIADRFMASIEVITSQEKEITIKKPNGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHNFDAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGDHRKVKHLRVFFVTAAWSIFAYTWLYLILAVISPGVVEVWEGLLTLFFFPICVVFAWVADRRLLFYKYVNKRYRVGKQRGMIIETEGEPELQSKADIEMDGQMLNSHGEDFLDGAVNTDIKEMDEEEARREMARILKDLKQKHPEKEMEQLIELANYQVLSQQQKSRAFYRCQATRLMTGAGNILKKHAADQARKAICTHELRTEVSDNDFSSKIFFDPGTYQCLENCGSVALNVVRRGGD---LTSTISVSYRTEDGTANAGSDYEFSEGVIVFNPGETEKEIRIEIIDDDIFEEDEHFLVHLSNIQVLSESRNNGSPVLNHVDSLAGLGL--PSTATVTIFDDDHAGIFAFEEQMMHVSESIGIMEVKVVRTSGARGAVVVPYKTIEGTAKGGGEDFEDTHGVLEFQNDEISKTIKVKIVDHDEYDKQASFYLQLQEPEWRRRGWTGGFVKTDKQLFGRDVYRKVQGRDNPVPSTIINLAEDISLSQKEQEERRIAEMGRPTLGDNTRLEVVIEESYEFKSTVDKLIKKTNLALLVGTNSWREQFVEAITVNSGGDDDEEC---SEEKLPSCFDYVMHFLTVFWKILFAFVPPTDYWNGWACFVVSISMIGLLTAVIGDLASHFGCTVGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADACIGNVTGSNAVNVFLGIGVAWSIAAIYHQWNGQYFRVQPGTLAFSVTLFTIFAFVCIAVLMYRRRPEIGGELGGPRTAKRITSSLFFSLWLLYIVLSSLEAYCIIKGF 983
BLAST of slc8a-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000794.1 (pep scaffold:Pmarinus_7.0:GL477892:73629:76552:-1 gene:ENSPMAG00000000728.1 transcript:ENSPMAT00000000794.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 459.529 bits (1181), Expect = 1.628e-149 Identity = 276/557 (49.55%), Postives = 371/557 (66.61%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYAL--EGDHELHCNHSLEDAHL-------------DGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQ-----KIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRA-VTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATG-GTDYIEVESYLEFMNDQ 2065
C +GI+LP+W P + S+GDK+ARA VYFV+L+Y+FLGVSIIADRFMASIEVITS+E+++ +++ +GE T VR+WNETVSNLTLMALGSSAPEILLS+IEICG FEAGDLGP TIVGSAAFN+F+II CVY IPDGE R+IKHL VF +TA+WS+FAYIWLYLI+A SP V+ +WEALLTF FF + V+ A+VAD ++ K++ ++Y + + EGD N ++ L DG++K +++++R D I++++E++ K P D L E A + L + KSRAFYR+QA R +TG+GN++KK + Q + ++ E++ + KI F+PG Y EN G+ + V R G D + V Y TE+GTATAG D+ + G ++F+ GE QK I ISIIDDDIFE DEHF++ L A VT+DG +++ L + L+EP +AT+ + DDDHAGIF FEE V+ES G E KV R+SGARG V+VPYR+ TA G G DY + LEF ND+
Sbjct: 58 CARGIILPIWVP-NNPSVGDKVARAIVYFVALIYMFLGVSIIADRFMASIEVITSQEKEITIKRPDGETTTTTVRVWNETVSNLTLMALGSSAPEILLSIIEICGHGFEAGDLGPSTIVGSAAFNMFVIIAICVYSIPDGETRKIKHLRVFFVTAAWSIFAYIWLYLILAVISPNVVDIWEALLTFMFFPICVVFAWVADRRLLFYKYMYKKYRADKHRGIIIETEGDRP-RMNIEMDGRMLNYETDVVPDGMLVDGEEK----DIDESRRDMIKLLKELKQKYPEKDLDQLVELANYQALTQQQKSRAFYRIQAIRMMTGAGNILKKHAAD----QARKAMSVQNIESDGESDFVSKICFEPGAYQCFENCGSCILTVSRKGGD---TSGFVSVRYKTENGTATAGSDFEFSEGKIVFKPGETQKEISISIIDDDIFEEDEHFYVRLSDVEAEVTEDGPEINHVSLPK-----ALLVEPTVATVTIFDDDHAGIFMFEEKVMRVSESVGVMEAKVMRTSGARGTVVVPYRTMEGTARGSGDDYEDSFGELEFHNDE 596
BLAST of slc8a-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006683.1 (pep scaffold:Pmarinus_7.0:GL476710:281470:285756:-1 gene:ENSPMAG00000006040.1 transcript:ENSPMAT00000006683.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 333.569 bits (854), Expect = 4.761e-106 Identity = 166/297 (55.89%), Postives = 220/297 (74.07%), Query Frame = 2
Query: 2210 NHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
H + ++ +D+ ++ I +MG+P LG+ ++VII+ES EFK VD L++ L+ +GT+SWKEQF +AITVS D +D ++ EEKLPSC DYVMHFLT+FWKVLFAFVPPTD GW F V I VIG LTA+IGDLAS FGCT+G+ ++VTA+ FVA+GTS+PDTFASKVAA+ D AD+SVGNVTGSNAVNVFLGIG+AW+IA+V+ + F V G+L FSVT+F +FA + ++ RR VGGELGGPR++K+ TT F+ LW++Y++ + LE YCH+K F
Sbjct: 3 KHENGLQAETDK--EEAQRIAEMGRPILGENSRLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWKEQFKDAITVSA--GDDDDDEESGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTDVWNGWACFLVSISVIGLLTAMIGDLASHFGCTVGLKDSVTAVVFVALGTSIPDTFASKVAAVQDQFADASVGNVTGSNAVNVFLGIGIAWTIASVHCWANNKKFYVDPGTLAFSVTLFTVFAFICVGVLMWRRRPSVGGELGGPRNMKLMTTGLFILLWLIYILFAGLEAYCHVKAF 295
BLAST of slc8a-1 vs. Ensembl Sea Lamprey
Match: adgrv1 (adhesion G protein-coupled receptor V1 [Source:NCBI gene;Acc:415105]) HSP 1 Score: 72.7886 bits (177), Expect = 4.806e-13 Identity = 76/224 (33.93%), Postives = 114/224 (50.89%), Query Frame = 2
Query: 1577 IEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDG--KKVSINQLTEQNIYGVELIEPFIATIMVLDDDHA-GIFNFEEAETV-VAESCGEAEIKVCRSSGARGVVLVPYRSRSDTA-TGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIEL----GEPI----LVKKPGIGKSNIPKEFTGF 2209
+ + Y T GTAT G DY G ++F+ GE K + + I++D+I E E F++N+ + ++ DG K+ + E GV PF +++ DD A G+ F+ A + VAE G + + R G G V+V Y SR TA GG DY+ + FM+ Q +FI V+I DD+E E +E F I+L G + L+ I KS+ P GF
Sbjct: 4312 VRLLYLTVPGTATEGRDYERLHGDLVFEEGERLKLLGLKILNDEISEGPEDFYLNITQVQLIS-DGYTKREHGSGAEEPPALGV----PFSLRVLIEKDDGAEGVIEFDSASGMSVAEEDGVLLVPLARHKGTYGSVMVLYVSRGVTAQPGGEDYLLPDGAALFMDGQNVSFINVSITDDDEREFEETFEIQLVSTTGGAVLGSRLIATITIAKSDAPNGLIGF 4530
BLAST of slc8a-1 vs. Ensembl Sea Lamprey
Match: slc24a4b (solute carrier family 24 member 4b [Source:ZFIN;Acc:ZDB-GENE-081031-75]) HSP 1 Score: 70.4774 bits (171), Expect = 1.379e-12 Identity = 53/152 (34.87%), Postives = 76/152 (50.00%), Query Frame = 2
Query: 557 MYLFLGVSIIADRFMA-SIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEIC-GSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEA 1006
MY+F ++++ D F S+E I+ + + +E V+ T MA GSSAPE+ SVI C G GD+G GTIVGSA FN+ IIG C G++ R+ S+F SVF I + +I F E++ WE+
Sbjct: 32 MYMFYALALVCDDFFVPSLEKISERLQL------------------SEDVAGATFMAAGSSAPELFTSVIVWCEGVFVTKGDVGVGTIVGSAVFNILCIIGVCGLF--AGQIVRLTWWSLFRD----SVFYTISIIALILFICDEIVSWWES 159 HSP 2 Score: 57.3806 bits (137), Expect = 1.374e-8 Identity = 35/112 (31.25%), Postives = 60/112 (53.57%), Query Frame = 2
Query: 2588 SFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVF 2923
SF + + I + V+ + + G T+G+ + + ITF+A GTS+PD AS + A D +V N GSN ++ +G+GL W++ + + GS + S L +SV +
Sbjct: 382 SFVISTIWIAVFSYVMVWMVTVIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVA-RQGMGDMAVSNSIGSNVFDILVGLGLPWALQTLLVDY-GSHVEINSRGLIYSVVLL 491
BLAST of slc8a-1 vs. Ensembl Sea Lamprey
Match: slc24a1 (solute carrier family 24 member 1 [Source:ZFIN;Acc:ZDB-GENE-060503-191]) HSP 1 Score: 61.2326 bits (147), Expect = 9.020e-10 Identity = 48/162 (29.63%), Postives = 80/162 (49.38%), Query Frame = 2
Query: 539 VYFVSLMYLFLGVSIIADRF-MASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLI-----IAFFSPEVIQVWEA 1006
++ + ++Y+F+ ++I+ D F + ++ VIT E+ I ++ V+ T MA G SAPE+ S+I + S+ ++G GTIVGSA FN+ +IG C R I L+ W +F + Y++ I FF +IQ WE+
Sbjct: 36 LHMLGMIYMFIALAIVCDEFFVPALGVIT--EKLAI----------------SDDVAGATFMAAGGSAPELFTSLIGVFISH---SNVGIGTIVGSAVFNILFVIGMCAVF-----SREI------LVLTWWPLFRDVSFYIVGLSMLIIFFLDNLIQWWES 165
BLAST of slc8a-1 vs. Ensembl Nematostella
Match: EDO46793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP49]) HSP 1 Score: 775.778 bits (2002), Expect = 0.000e+0 Identity = 471/940 (50.11%), Postives = 625/940 (66.49%), Query Frame = 2
Query: 374 SCIVVIEFLSWIQCEP-LKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKK-NGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFL--KRRYLRKNVKSYALEGDHEL--------------------HCNHSLEDAHLDGDKKENLTELEKTRMD-YIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIK--KSKLERRLSQDPD-KLGLKEKENNNQ---KIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIY---GVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCH 3088
S ++++ + W+ +P L C+ LN T CK+G++LP W S G +I RAFVY +SL++ FLGVSII+DRFM+SIE+ITSKE+ V ++ K +G+ + + V+IWNETVSNLTLMALGSSAPEILLSVIEI G+NF+AGDLGP TIVGSAAFNLF+IIG CVYVIPD EVR+IKHL VF+ITA+ SVFAYIWLY+IIA S VI++WE +LTF F V AY+AD ++ + L KRR ++ S GD ++ + ++E A D + L +L + R D I+V+R+I+ K PN D +T+E + E L PKSRAFYR++ATR + GSGN++K KLE+ S D KL LK+ E ++ K++F P Y V EN G+ + + R G D + V++ TEDGTA AGDDY T G + F+ GE +K I + IIDDD+FE DEHF + L + R DG V +N Y ++ + ATI++LDDD+ G+F FE+A V E+ A +KV R++GARG V +PY + TA GG DY + LEF++D+T I + IIDD +YEK E F + LGEP +VK+ ++ P + H +++ + IE++GKPRLG+ +I+VII ES EF++ VD +L L+ +GTSSW+EQF +A TV G +D + DD E P+ DY+MHFLT+FWK+LFAFVPPTD GGW F V I+ IG LTAVIGDLAS FGCTI + ++V AITFVA+GTSLPDTFASKVAAIND++ADSSVGNVTGSN+VNVFLGIG+AWS+AA+YH G+ F+V GSLGFSV VFCI A AI M++RR+ +VGGELGGPR +KI T+I V LW++Y++LSSL+ YCH
Sbjct: 13 SSVLLLVLICWLIDQPVLARQDCD-LN-TECKEGVILPKWG--GDPSTGARIGRAFVYLLSLLFFFLGVSIISDRFMSSIEIITSKEKDVKIKDKVSGKERVLTVKIWNETVSNLTLMALGSSAPEILLSVIEIIGNNFKAGDLGPSTIVGSAAFNLFVIIGVCVYVIPDDEVRKIKHLRVFIITAACSVFAYIWLYIIIAVSSKGVIEIWEGILTFLMFPALVGCAYIADRRLLFYRALRGKRRKQKRGGVSVIQTGDFDVIGVRIKQDGLTPEEGAEENGYPLQTVEGAE-DLEDDYALHDLTEERKDKAIQVLRDIKAKYPNADRETVERLLEQENLRLQPKSRAFYRIEATRKMVGSGNIVKMKHDKLEKASSSVADVKLELKDLEYDDPEVVKVYFSPEEYEVKENCGSVFMTITRAGGD---VNNTVFVDFKTEDGTAKAGDDYDKTEGTICFRPGETEKTISVVIIDDDVFEEDEHFTVALSNVRIAGPDGDLV-------RNTYRGPAGKVAKGGRATIVILDDDYPGLFTFEDASMEVPEADRVARVKVTRNTGARGTVRLPYHTVEGTAKGGGQDYEDAVGELEFLDDETHKIIDIAIIDDEDYEKKETFSVILGEPYVVKE----DAHFPTD------------HDEEMDEEKKRIEELGKPRLGEFPKIEVIIIESKEFRNTVDKMLAKANLALVVGTSSWREQFKDAFTVG-GSDD--NGDDEGEPAPPTYGDYMMHFLTVFWKILFAFVPPTDIWGGWACFVVSILWIGVLTAVIGDLASHFGCTIYLADSVVAITFVALGTSLPDTFASKVAAINDETADSSVGNVTGSNSVNVFLGIGIAWSVAAIYHAVNGNEFKVDPGSLGFSVCVFCIGAAFAITLMMVRRSAKVGGELGGPRQIKIITSILLVALWVLYILLSSLQTYCH 918
BLAST of slc8a-1 vs. Ensembl Nematostella
Match: EDO35472 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLD3]) HSP 1 Score: 421.779 bits (1083), Expect = 4.264e-133 Identity = 301/800 (37.62%), Postives = 431/800 (53.87%), Query Frame = 2
Query: 530 RAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNG-EMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSN-FEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKN-----PNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLG------------LKEKENNNQK--IFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNL--LRHGQLSEF-IGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVY 2857
R F+Y ++L++ F+GV+I+AD FM +IE ITSK +KV + K+N E+ + VR+WNETV+NLTLMALGSSAPEILLS+IEI N FEAG LGP TIVGSAAFNL I G CV +P E RRIK ++VF +TA S+ AYIWL++I++ + +V+++WEA+LTF FF + V+ AY+ D K+Y G E L GD EL ++ ++ +I +KN P+I + + + PK+ +YR+ A R + G + K K++ RL+ ++L L K++ + I F VMEN + V R+G A V + T DGTA +G DY+A V++F+ GE K ++I IIDD+ +E +E FF+ L +P + G V +TE I +++DD G+ + ++ V+ ES G+A V R+ G G + V +++ +A G DY L F + + I + I+DD +EKDE F +E+ +P G LG I V I E+K + D + L H L +G+SSW +QF +A++V+ G D E++ + +DY+MHFLTL WKV+FA VPP + GGWV+F V + IG LTA++GDLA+ FGC +G+ N VTA TFVA+GTSLPD FASK AAIN+ AD+ +GNVTGSN+VNVFLG+G W IA +Y
Sbjct: 40 RTFIYLIALLWCFMGVAIVADIFMCAIETITSKTKKVKIAKQNSSEIIEVEVRVWNETVANLTLMALGSSAPEILLSIIEITIMNGFEAGALGPSTIVGSAAFNLLCITGVCVMAVPKFETRRIKSMNVFAVTAITSLLAYIWLFIILSVNTKDVVELWEAILTFLFFPILVIIAYIMD------------------KNYCCPGRVEPEGMLEL------GDNSHG--ELFVISKIFLMILNKI-MKNEVSQIPDITEDDTAKLVAAHIKAKQPKNYGYYRVGAIRNIGGGHKL--KPKMDPRLNMIYEELSEVGFSTSGASTILHGKKDAIKPAVIEFATTKCAVMENDKLVKIGVMRSGNLNVSA----SVNFETIDGTAESGSDYVAKKDVMVFKPGETLKHLDIEIIDDNEWEENEIFFVKL-APYDMKDAGTVVGKQSITE---------------ITIINDDEPGVLSLQKPSFVIKESIGKANFLVERTGGTDGTIKVTWKTTDQSAINGKDYHGGIGELVFEHGEQMKDITIEIMDDKAFEKDECFLLEIMDP------------------------------------------TGGATLGKITRSVVTIVNDDEYKRLFDRVVALTHLNLDRLELGSSSWGQQFRDALSVNGG--DIENA---------TTMDYIMHFLTLAWKVIFAAVPPCTWAGGWVTFSVALCFIGILTAIVGDLATIFGCLVGLKNEVTAFTFVALGTSLPDLFASKAAAINEKYADACIGNVTGSNSVNVFLGLGTPWVIATIY 737
BLAST of slc8a-1 vs. Ensembl Nematostella
Match: EDO45642 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSI7]) HSP 1 Score: 222.246 bits (565), Expect = 2.868e-60 Identity = 144/430 (33.49%), Postives = 223/430 (51.86%), Query Frame = 2
Query: 1952 SSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHI-----------ELGEPILVKKPGIGKSNIPKEFT---GFNHVSEVKTHSDQLVSQSSEIEDM---------GKPRLGDIKEIKVIIKESLEFKHVVDNLL--RHGQLSEFI----GTSSWKEQFV-----------------EAITVSPG-ENDTEDSDDLSEEKLP-SCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKG 3097
S G+ V Y + +A G +Y V+ + F + +++ I+ ++ K++ F++ +LGEP L + I ++P EF+ H + V + V + + G + G E++ ++ +++ V D LL HG++S+ I T + FV + +S G + +D +LP + +D++MHFLT FWKVLFAF+PP LGGW +F V ++ I ALTAVI L GC + + N+VT IT +A+GTSLPDT AS+ AA+ D AD+++GN+TG N+VNVFLG+GL W ++ YH +G+ ++V SG+L FSV VF + + ++LRR GELGGP K T + + LW +YV+LSSL Y HI G
Sbjct: 411 SPGSSQRFSVDYETHDGSAKNGKEYQTVKGTMAFRAGINKHILRIPILPCEDFSKNKDFYVLLKNPSPEGITDLGEPNLTRITII-DDDMPGEFSFEQASYHANFVTGEATCTVVRRKGCDGTVTLKYHTMNGTAKGGTKNELEA---KTCDYEQVTDGLLTFHHGEMSKHITVKINTETQDTNFVVLLHDPSTGARIGNRTATVVHISSGIAMIIQGDEDKDGNELPLNSIDFIMHFLTFFWKVLFAFIPPRPLLGGWPAFVVSLLFIAALTAVIEQLGKLLGCVVDLRNSVTGITIIAIGTSLPDTMASRSAALQDTGADAAIGNITGYNSVNVFLGLGLPWVMSTCYHAARGTVYKVSSGNLAFSVLVFALCGGVCLFLLVLRR-YLYKGELGGPTLSKWMTGLLLLFLWFIYVVLSSLMAYGHISG 835 HSP 2 Score: 208.764 bits (530), Expect = 7.640e-56 Identity = 187/608 (30.76%), Postives = 279/608 (45.89%), Query Frame = 2
Query: 530 RAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVI-VRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEI-----CGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLE-EQAQIEVL--NRVPKSRAF-YRMQATRTLTGSGNVIKKSKLER------RLSQDPDKL-----GLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRT-------------GTDEQIAKTMIE-------------------VEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKK-----VSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGT---------DYIEV-ESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEP 2149
R F+Y + ++YLFLG++I+AD FM+ IEVITSK+RKV + GE I V +WNETV+NLTLMALGSSAPEILL+V+E G LG TIVGSA+FNL +I CV +P+G V+RI+ VF++TA WS+FAY+W+ +I + SPEVI++WEA +T FF L VLTA+ D + + R + S + L D + +L L ++ +++ R N ++ KT Q+ VL P S A +R R L ++ S +R R KL G +++N + F Y+V+++ ++ + ++ IA T+ E V+Y T DG+A G +Y G + F++G ++ L+ P +D K V + + + I +L EP + I ++DDD G F+FE+A GEA V R G G V + Y + + TA GGT DY +V + L F + + I V I N +D F + L +P
Sbjct: 37 RGFLYILGMLYLFLGIAIVADIFMSCIEVITSKKRKVTRYDHEKGESVEIEVFVWNETVANLTLMALGSSAPEILLAVVETGQELALGQTTATDGLGTFTIVGSASFNLLLITAVCVVSVPNGTVKRIREFGVFVVTAVWSMFAYVWMLFVIQWNSPEVIELWEAFMTLAFFPLLVLTAWCTDHGWWCRN-------RGKILSVDPPQVIVIIFTKGLVD-------RNSLALLR-----FVRFVKQAR--NCDVVSKTSRFSHLQVRVLGFTDAPSSHAMIHRSMELRALEQHRGSVRNSSFDRFRHAALRSVTRSKKLIKINEGEDVEDDNLNRFVFGTSSYSVLKSAKHIDLEIILLQNNNNNKNKEMIYAHNDSIADTISENSFEDGVTPSSPGSSQRFSVDYETHDGSAKNGKEYQTVKGTMAFRAGINKHI--------------------LRIPILPCEDFSKNKDFYVLLKNPSPEGI--TDLGEPNLTRITIIDDDMPGEFSFEQASYHANFVTGEATCTVVRRKGCDGTVTLKYHTMNGTAKGGTKNELEAKTCDYEQVTDGLLTFHHGEMSKHITVKI---NTETQDTNFVVLLHDP 598
BLAST of slc8a-1 vs. Ensembl Nematostella
Match: EDO42266 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1V5]) HSP 1 Score: 73.1738 bits (178), Expect = 5.976e-13 Identity = 69/229 (30.13%), Postives = 104/229 (45.41%), Query Frame = 2
Query: 1475 IFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEP-------FIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIEL 2140
+F P Y V E+VGT N+ VKR D I + + Y +A G DY A SGV+ F E K + + I+ D E DE + L+S R + + L + G++L P ++ ++ +D+ GI F V ES G + + R+ G G++ V Y + TAT G DY + F Q+ A + V IIDD E+ E F ++L
Sbjct: 3480 VFEPPYAYNVSEDVGTVNMTVKRNKGD--IGR--LSANYSVTSSSAMPGQDYEAMSGVLEFADKEQTKKLTLKILQDVSPELDETILVQLQSVRLLDR--------TLNYSTVQGLQLNMPPRIGDQSAVSVTLLKNDEAHGIVQFVVTSATVRESDGHVSLGLQRTGGTFGIIQVNYNVLNGTATHGEDYNVSSGVIVFKAGQSSAQLIVGIIDDVIPEQAETFSVQL 3696 HSP 2 Score: 51.6026 bits (122), Expect = 2.275e-6 Identity = 38/116 (32.76%), Postives = 54/116 (46.55%), Query Frame = 2
Query: 1862 DDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESY------LEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIP 2191
+DD AG+ F + V ES G + V RS G+ G V V Y + + DY + S+ L F++ Q E I+V I DD E +E IL KPG+G + +P
Sbjct: 2147 NDDPAGVIGFSQTRIDVNESIGAFNVTVLRSQGSLGTVTVKYFIKLTSTAIPNDY-SIPSFGGGEETLTFVDGQREQNIEVKITDDTIPEDNESI-------ILGLKPGVGAALVP 2254
BLAST of slc8a-1 vs. Ensembl Nematostella
Match: EDO32048 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW69]) HSP 1 Score: 61.2326 bits (147), Expect = 1.518e-9 Identity = 40/106 (37.74%), Postives = 56/106 (52.83%), Query Frame = 2
Query: 545 FVSLMYLFLGVSIIAD-RFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYC 859
F+ +Y+F V+I+ D F+ +E+I + +QT V+ T MALGSSAPE+ SVI G GD+G GTI+GSA FN+ +IG C
Sbjct: 29 FIISLYMFWAVAIVCDDYFVPCLEIICDRLG----------LQT--------DVAGATFMALGSSAPELFASVI---GVFITKGDIGVGTILGSAVFNVLFVIGVC 113 HSP 2 Score: 55.0694 bits (131), Expect = 1.089e-7 Identity = 45/144 (31.25%), Postives = 72/144 (50.00%), Query Frame = 2
Query: 2582 WV--SFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSI-AAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLL-------RRNRRVG 2983
WV SF +CIV IG + V+ + + G T + ++V ++ VA G+S+PD +S A D D +V + GSN ++ L +G+ W I V+ + S+ + S L S C F L +IA L+ N++VG
Sbjct: 320 WVVLSFIICIVWIGVTSYVLVWMVTVIGYTFLIPDSVMGLSLVAFGSSVPDCLSSLFVARKGD-GDMAVSHTVGSNVFDILLCLGIPWLIKTTVWEY--DSSVVINSHGLFIS----CFFILGSIAVTLIIIWYYKWTLNKKVG 456
BLAST of slc8a-1 vs. Ensembl Medaka
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:101162981]) HSP 1 Score: 848.966 bits (2192), Expect = 0.000e+0 Identity = 460/897 (51.28%), Postives = 608/897 (67.78%), Query Frame = 2
Query: 455 TSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLE------------DAHLDGDKKENLTELEK--TRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
T C +G++L +WKP + +++ARA +YF+ L+Y+FLGVSIIADRFMASIEVITS+ERK+ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG F+AG+LGP TIVGSAAFN+F+IIG CV VIPDGE R++KHL VF +TA WSVFAY WLYLI+A FSP V+++WE LLT FFF V AYVAD ++ K++ +RY K +E + +L +E D +DG+ K + E+++ R + +++E++ K+P + + L E A +VL + KSRAFYR QATR +TG+GNV+KK ++ + + + K+FFDPG Y +EN G+ + V R G D T I V+Y TEDGTA AG DY T G ++F+ GE +K I + IIDDDIFE DEHF ++L + R ++ N + G+ P A++ + DDDHAG+F F+E V+ES G E+KV R++GARG V+VPY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP+L++ + T H+ E + + +MG+P LG+ ++VII+ES EFK VVD L++ L+ IGT+SW+EQFVEAITVS G+ D D+ SE+KLPS DYVMHFLT+FWK+LFAFVPPTDY GW F + IVVIG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH+ +G F+V G+L FSVT+F IFA I+ ++ RR +GGELGGPR KI TT F LW++Y+I SSLE YCH+KGF
Sbjct: 50 TECMQGVILSVWKP-DNPTFSERLARATIYFLGLIYMFLGVSIIADRFMASIEVITSQERKITIKKPNGEKITTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHGFQAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGETRKVKHLRVFFVTAFWSVFAYTWLYLILAVFSPGVVEIWEGLLTLFFFPFCVGFAYVADRRLLFYKYVYKRYRAGKRKGVIIETEGQLELPLKVEVETDNKMLNSQVDKFMDGESKVEVKEVDEDEARREVARILKELKQKHPEKEMEQLMELANYQVLTQQQKSRAFYRCQATRIMTGAGNVLKKHATDQAKRAQLNICSEVPTNSFSSKVFFDPGTYQCLENCGSVALNVVRKGGD---FTTAIAVDYWTEDGTANAGSDYKFTEGTLVFKPGETEKEIHVDIIDDDIFEEDEHFLVHLSNVRVISGGPHCQETNHVDALAGLGL----PCSASVTIFDDDHAGVFTFKEPVITVSESIGVLEVKVMRTAGARGAVVVPYKTIEGTAKGGGEDFEDTHGALEFENDEVLKTIRINIIDDEEYEKNKNFFLEMGEPLLLEMTCSVADDATDCVTAVGHIGEER-----------RVAEMGRPVLGEHVRLEVIIEESYEFKSVVDKLIKKTNLALVIGTNSWREQFVEAITVSTGDED----DECSEQKLPSGFDYVMHFLTVFWKLLFAFVPPTDYCNGWACFVISIVVIGLLTAWIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHYSQGEEFKVDPGTLAFSVTLFTIFAFICISVLIYRRRPSIGGELGGPRVPKILTTCLFFSLWLLYIIFSSLEAYCHVKGF 923
BLAST of slc8a-1 vs. Ensembl Medaka
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:101162981]) HSP 1 Score: 848.581 bits (2191), Expect = 0.000e+0 Identity = 459/895 (51.28%), Postives = 607/895 (67.82%), Query Frame = 2
Query: 461 CKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLE------------DAHLDGDKKENLTELEK--TRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
C +G++L +WKP + +++ARA +YF+ L+Y+FLGVSIIADRFMASIEVITS+ERK+ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG F+AG+LGP TIVGSAAFN+F+IIG CV VIPDGE R++KHL VF +TA WSVFAY WLYLI+A FSP V+++WE LLT FFF V AYVAD ++ K++ +RY K +E + +L +E D +DG+ K + E+++ R + +++E++ K+P + + L E A +VL + KSRAFYR QATR +TG+GNV+KK ++ + + + K+FFDPG Y +EN G+ + V R G D T I V+Y TEDGTA AG DY T G ++F+ GE +K I + IIDDDIFE DEHF ++L + R ++ N + G+ P A++ + DDDHAG+F F+E V+ES G E+KV R++GARG V+VPY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP+L++ + T H+ E + + +MG+P LG+ ++VII+ES EFK VVD L++ L+ IGT+SW+EQFVEAITVS G+ D D+ SE+KLPS DYVMHFLT+FWK+LFAFVPPTDY GW F + IVVIG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH+ +G F+V G+L FSVT+F IFA I+ ++ RR +GGELGGPR KI TT F LW++Y+I SSLE YCH+KGF
Sbjct: 35 CMQGVILSVWKP-DNPTFSERLARATIYFLGLIYMFLGVSIIADRFMASIEVITSQERKITIKKPNGEKITTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHGFQAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGETRKVKHLRVFFVTAFWSVFAYTWLYLILAVFSPGVVEIWEGLLTLFFFPFCVGFAYVADRRLLFYKYVYKRYRAGKRKGVIIETEGQLELPLKVEVETDNKMLNSQVDKFMDGESKVEVKEVDEDEARREVARILKELKQKHPEKEMEQLMELANYQVLTQQQKSRAFYRCQATRIMTGAGNVLKKHATDQAKRAQLNICSEVPTNSFSSKVFFDPGTYQCLENCGSVALNVVRKGGD---FTTAIAVDYWTEDGTANAGSDYKFTEGTLVFKPGETEKEIHVDIIDDDIFEEDEHFLVHLSNVRVISGGPHCQETNHVDALAGLGL----PCSASVTIFDDDHAGVFTFKEPVITVSESIGVLEVKVMRTAGARGAVVVPYKTIEGTAKGGGEDFEDTHGALEFENDEVLKTIRINIIDDEEYEKNKNFFLEMGEPLLLEMTCSVADDATDCVTAVGHIGEER-----------RVAEMGRPVLGEHVRLEVIIEESYEFKSVVDKLIKKTNLALVIGTNSWREQFVEAITVSTGDED----DECSEQKLPSGFDYVMHFLTVFWKLLFAFVPPTDYCNGWACFVISIVVIGLLTAWIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHYSQGEEFKVDPGTLAFSVTLFTIFAFICISVLIYRRRPSIGGELGGPRVPKILTTCLFFSLWLLYIIFSSLEAYCHVKGF 906
BLAST of slc8a-1 vs. Ensembl Medaka
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:101162981]) HSP 1 Score: 848.195 bits (2190), Expect = 0.000e+0 Identity = 462/900 (51.33%), Postives = 612/900 (68.00%), Query Frame = 2
Query: 455 TSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLE------------DAHLDGDKKENLTELEK--TRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSE---IEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
T C +G++L +WKP + +++ARA +YF+ L+Y+FLGVSIIADRFMASIEVITS+ERK+ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG F+AG+LGP TIVGSAAFN+F+IIG CV VIPDGE R++KHL VF +TA WSVFAY WLYLI+A FSP V+++WE LLT FFF V AYVAD ++ K++ +RY K +E + +L +E D +DG+ K + E+++ R + +++E++ K+P + + L E A +VL + KSRAFYR QATR +TG+GNV+KK ++ + + + K+FFDPG Y +EN G+ + V R G D T I V+Y TEDGTA AG DY T G ++F+ GE +K I + IIDDDIFE DEHF ++L + R ++ N + G+ P A++ + DDDHAG+F F+E V+ES G E+KV R++GARG V+VPY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP+L++ ++ G +S H+ L + E + +MG+P LG+ ++VII+ES EFK VVD L++ L+ IGT+SW+EQFVEAITVS G+ D D+ SE+KLPS DYVMHFLT+FWK+LFAFVPPTDY GW F + IVVIG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH+ +G F+V G+L FSVT+F IFA I+ ++ RR +GGELGGPR KI TT F LW++Y+I SSLE YCH+KGF
Sbjct: 54 TECMQGVILSVWKP-DNPTFSERLARATIYFLGLIYMFLGVSIIADRFMASIEVITSQERKITIKKPNGEKITTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHGFQAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGETRKVKHLRVFFVTAFWSVFAYTWLYLILAVFSPGVVEIWEGLLTLFFFPFCVGFAYVADRRLLFYKYVYKRYRAGKRKGVIIETEGQLELPLKVEVETDNKMLNSQVDKFMDGESKVEVKEVDEDEARREVARILKELKQKHPEKEMEQLMELANYQVLTQQQKSRAFYRCQATRIMTGAGNVLKKHATDQAKRAQLNICSEVPTNSFSSKVFFDPGTYQCLENCGSVALNVVRKGGD---FTTAIAVDYWTEDGTANAGSDYKFTEGTLVFKPGETEKEIHVDIIDDDIFEEDEHFLVHLSNVRVISGGPHCQETNHVDALAGLGL----PCSASVTIFDDDHAGVFTFKEPVITVSESIGVLEVKVMRTAGARGAVVVPYKTIEGTAKGGGEDFEDTHGALEFENDEVLKTIRINIIDDEEYEKNKNFFLEMGEPLLLEMS-------ERKGGGITFLSFDPAHTRVLTKKEEEERRVAEMGRPVLGEHVRLEVIIEESYEFKSVVDKLIKKTNLALVIGTNSWREQFVEAITVSTGDED----DECSEQKLPSGFDYVMHFLTVFWKLLFAFVPPTDYCNGWACFVISIVVIGLLTAWIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHYSQGEEFKVDPGTLAFSVTLFTIFAFICISVLIYRRRPSIGGELGGPRVPKILTTCLFFSLWLLYIIFSSLEAYCHVKGF 934
BLAST of slc8a-1 vs. Ensembl Medaka
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:101162981]) HSP 1 Score: 845.114 bits (2182), Expect = 0.000e+0 Identity = 461/897 (51.39%), Postives = 608/897 (67.78%), Query Frame = 2
Query: 455 TSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLE------------DAHLDGDKKENLTELEK--TRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
T C +G++L +WKP + +++ARA +YF+ L+Y+FLGVSIIADRFMASIEVITS+ERK+ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG F+AG+LGP TIVGSAAFN+F+IIG CV VIPDGE R++KHL VF +TA WSVFAY WLYLI+A FSP V+++WE LLT FFF V AYVAD ++ K++ +RY K +E + +L +E D +DG+ K + E+++ R + +++E++ K+P + + L E A +VL + KSRAFYR QATR +TG+GNV+KK ++ + + + K+FFDPG Y +EN G+ + V R G D T I V+Y TEDGTA AG DY T G ++F+ GE +K I + IIDDDIFE DEHF ++L + R ++ N + G+ P A++ + DDDHAG+F F+E V+ES G E+KV R++GARG V+VPY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP+L++ I F F+ E + + +MG+P LG+ ++VII+ES EFK VVD L++ L+ IGT+SW+EQFVEAITVS G+ D D+ SE+KLPS DYVMHFLT+FWK+LFAFVPPTDY GW F + IVVIG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH+ +G F+V G+L FSVT+F IFA I+ ++ RR +GGELGGPR KI TT F LW++Y+I SSLE YCH+KGF
Sbjct: 20 TECMQGVILSVWKP-DNPTFSERLARATIYFLGLIYMFLGVSIIADRFMASIEVITSQERKITIKKPNGEKITTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHGFQAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGETRKVKHLRVFFVTAFWSVFAYTWLYLILAVFSPGVVEIWEGLLTLFFFPFCVGFAYVADRRLLFYKYVYKRYRAGKRKGVIIETEGQLELPLKVEVETDNKMLNSQVDKFMDGESKVEVKEVDEDEARREVARILKELKQKHPEKEMEQLMELANYQVLTQQQKSRAFYRCQATRIMTGAGNVLKKHATDQAKRAQLNICSEVPTNSFSSKVFFDPGTYQCLENCGSVALNVVRKGGD---FTTAIAVDYWTEDGTANAGSDYKFTEGTLVFKPGETEKEIHVDIIDDDIFEEDEHFLVHLSNVRVISGGPHCQETNHVDALAGLGL----PCSASVTIFDDDHAGVFTFKEPVITVSESIGVLEVKVMRTAGARGAVVVPYKTIEGTAKGGGEDFEDTHGALEFENDEVLKTIRINIIDDEEYEKNKNFFLEMGEPLLLEMSERKGGGIT--FLSFDPEEEER-----------RVAEMGRPVLGEHVRLEVIIEESYEFKSVVDKLIKKTNLALVIGTNSWREQFVEAITVSTGDED----DECSEQKLPSGFDYVMHFLTVFWKLLFAFVPPTDYCNGWACFVISIVVIGLLTAWIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHYSQGEEFKVDPGTLAFSVTLFTIFAFICISVLIYRRRPSIGGELGGPRVPKILTTCLFFSLWLLYIIFSSLEAYCHVKGF 891
BLAST of slc8a-1 vs. Ensembl Medaka
Match: slc8a1a (sodium/calcium exchanger 1 [Source:NCBI gene;Acc:101162981]) HSP 1 Score: 844.729 bits (2181), Expect = 0.000e+0 Identity = 458/897 (51.06%), Postives = 605/897 (67.45%), Query Frame = 2
Query: 455 TSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLE------------DAHLDGDKKENLTELEK--TRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGG-TDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
T C +G++L +WKP + +++ARA +YF+ L+Y+FLGVSIIADRFMASIEVITS+ERK+ ++K NGE T VRIWNETVSNLTLMALGSSAPEILLSV+E+CG F+AG+LGP TIVGSAAFN+F+IIG CV VIPDGE R++KHL VF +TA WSVFAY WLYLI+A FSP V+++WE LLT FFF V AYVAD ++ K++ +RY K +E + +L +E D +DG+ K + E+++ R + +++E++ K+P + + L E A +VL + KSRAFYR QATR +TG+GNV+KK ++ + + + K+FFDPG Y +EN G+ + V R G D T I V+Y TEDGTA AG DY T G ++F+ GE +K I + IIDDDIFE DEHF ++L + R ++ N + G+ P A++ + DDDHAG+F F+E V+ES G E+KV R++GARG V+VPY++ TA GG D+ + LEF ND+ I++NIIDD EYEK++ F +E+GEP+L++ + K + + +MG+P LG+ ++VII+ES EFK VVD L++ L+ IGT+SW+EQFVEAITVS G+ D D+ SE+KLPS DYVMHFLT+FWK+LFAFVPPTDY GW F + IVVIG LTA IGDLAS FGCTIG+ ++VTA+ FVA+GTS+PDTFASKVAAI D AD+S+GNVTGSNAVNVFLGIG+AWSIAA+YH+ +G F+V G+L FSVT+F IFA I+ ++ RR +GGELGGPR KI TT F LW++Y+I SSLE YCH+KGF
Sbjct: 50 TECMQGVILSVWKP-DNPTFSERLARATIYFLGLIYMFLGVSIIADRFMASIEVITSQERKITIKKPNGEKITTTVRIWNETVSNLTLMALGSSAPEILLSVVEVCGHGFQAGELGPNTIVGSAAFNMFVIIGLCVSVIPDGETRKVKHLRVFFVTAFWSVFAYTWLYLILAVFSPGVVEIWEGLLTLFFFPFCVGFAYVADRRLLFYKYVYKRYRAGKRKGVIIETEGQLELPLKVEVETDNKMLNSQVDKFMDGESKVEVKEVDEDEARREVARILKELKQKHPEKEMEQLMELANYQVLTQQQKSRAFYRCQATRIMTGAGNVLKKHATDQAKRAQLNICSEVPTNSFSSKVFFDPGTYQCLENCGSVALNVVRKGGD---FTTAIAVDYWTEDGTANAGSDYKFTEGTLVFKPGETEKEIHVDIIDDDIFEEDEHFLVHLSNVRVISGGPHCQETNHVDALAGLGL----PCSASVTIFDDDHAGVFTFKEPVITVSESIGVLEVKVMRTAGARGAVVVPYKTIEGTAKGGGEDFEDTHGALEFENDEVLKTIRINIIDDEEYEKNKNFFLEMGEPLLLEMKVLTKKE----------------------EEERRVAEMGRPVLGEHVRLEVIIEESYEFKSVVDKLIKKTNLALVIGTNSWREQFVEAITVSTGDED----DECSEQKLPSGFDYVMHFLTVFWKLLFAFVPPTDYCNGWACFVISIVVIGLLTAWIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHYSQGEEFKVDPGTLAFSVTLFTIFAFICISVLIYRRRPSIGGELGGPRVPKILTTCLFFSLWLLYIIFSSLEAYCHVKGF 912
BLAST of slc8a-1 vs. Planmine SMEST
Match: SMESG000077236.1 (SMESG000077236.1) HSP 1 Score: 1804.26 bits (4672), Expect = 0.000e+0 Identity = 916/917 (99.89%), Postives = 916/917 (99.89%), Query Frame = 2
Query: 350 MRGNLLFGSCIVVIEFLSWIQCEPLKNGACESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
MRGNLLFGSCIVVIEFLSWIQCEPLKNG CESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEALLTFFFFFLTVLTAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPIEISIIDDDIFEADEHFFINLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF
Sbjct: 1 MRGNLLFGSCIVVIEFLSWIQCEPLKNGVCESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEALLTFFFFFLTVLTAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPIEISIIDDDIFEADEHFFINLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 917
BLAST of slc8a-1 vs. Planmine SMEST
Match: SMESG000076607.1 (SMESG000076607.1) HSP 1 Score: 792.727 bits (2046), Expect = 0.000e+0 Identity = 448/901 (49.72%), Postives = 613/901 (68.04%), Query Frame = 2
Query: 437 CESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLE--DAHLD----------GDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKEN-NNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
C++LN+T C G++L +W+P G+S DK+ RA VYF+ + YLFLGVSIIADRFMA+IE+ITS+ERK ++KKNGE + V+IWNETVSNLTLMALGSSAPEILLS+IEI G NFEAG+LGPGTIVGSAAFNLF+IIG CV VIPD E R+ KHLSVF++T WS+FAYIWLYLI+AF SP V++VWEA+LTF FF LTV++AY+ADTKIF K+F + L K+ + L SLE D +L G E+ T L++ R++Y+ +I+++R N N++ LE A+IE+ R PKSRA+YR++A + LTG+ + I+K + +++ +K +N Q++ F P HYTV EN + +KR G E I+ T+I+V+Y TEDGTA G DY++ G + F+ G+ + I I IIDDDI+E DE+F++ LKSPR V K N+ Q ++L A +M+LDDD+ G F+FE+ + ++E+ G +IKV RSSGARG V +P ++ ++TA Y L F N+Q E I V I D+NEY K F +ELGEP S+Q+ QS D G+P+LG+I ++++ + E+ + K ++DNL+ G++ + I TS+W+EQF EA+T+ + +SD+ +PSC Y+ H+L+LFWK+LFAFVPP D L GW+ F+V + +IG LTA+IGD+AS FGC +G+T++VTAITFVA+GTSLPDTFASK AAINDD+AD+S+GNV GSNAVNVFLGIG+AW++A++YH G F V SGSLGFSVT+F I AL A++ MLLRR +++GGELGGP+ K T ++F +W++Y+I SSLE YCHIKGF
Sbjct: 7 CKALNNTKCVDGVLLSMWQPAIGISHTDKVIRAMVYFLYMCYLFLGVSIIADRFMAAIEIITSQERKFKIKKKNGETNIVYVKIWNETVSNLTLMALGSSAPEILLSIIEIIGKNFEAGELGPGTIVGSAAFNLFVIIGICVMVIPDNETRKTKHLSVFIVTTIWSLFAYIWLYLILAFISPGVVEVWEAVLTFLFFPLTVISAYLADTKIFFKQFFGTKVLGGFTKTDNSKNMPNLEDIPSLEQKDTNLKNQTELLADECGSSSESFT-LDQFRIEYMHLIKDLRKINSNLNLDDLEAMAEIELFKRRPKSRAYYRLKAMQYLTGTSDPIRKLRSISMINETE----IKYIDNLKVQEVTFFPDHYTVFENNKKVILTLKRVG--EGISTTVIDVDYYTEDGTAKDGSDYVSKIGTIRFEKGQLSQEIIIDIIDDDIYEEDEYFYVKLKSPRTV----KTFEENETALQ----IKLGSFSSAIVMILDDDYPGNFHFEKPKMKISENVGHIQIKVIRSSGARGQVKIPIKTIAETAINTIHYRMTTDELVFENNQIENHIDVYIYDENEYSKSILFSLELGEPT----------------------------SEQISIQS----DSGRPKLGNISKLEIEVTENPDLKKIIDNLIEKGKIEKVITTSTWREQFHEALTI----QKSNESDE-----MPSCTQYIFHYLSLFWKILFAFVPPADILNGWLCFFVSVFIIGVLTAIIGDVASAFGCHVGLTDSVTAITFVALGTSLPDTFASKCAAINDDTADASIGNVMGSNAVNVFLGIGIAWTLASIYHAVSGKKFLVDSGSLGFSVTLFTILALVAVSIMLLRRIKQIGGELGGPKPFKYITGVFFCFMWLIYLIFSSLEIYCHIKGF 851
BLAST of slc8a-1 vs. Planmine SMEST
Match: SMESG000041861.1 (SMESG000041861.1) HSP 1 Score: 474.552 bits (1220), Expect = 1.181e-153 Identity = 286/682 (41.94%), Postives = 418/682 (61.29%), Query Frame = 2
Query: 524 IARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKF---LKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGARGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPGIGKSNIPKEFTGFNHVSEVKTHSDQLVSQSSEIEDMGKPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVP 2560
I R+ VY ++L Y+F+GVSII+D+FMA+IE ITS+E+++ ++ K + TI VR+WNETVSNLTLMALGSSAPEI+LSVIE+CG NF++G LGPGTIVGSAAFNLFIIIG C+ V+PDGE+RRI+ L+VF +TA++SV AY+W+Y+I+ S +I+VWEA+LTF F LTV+ AY+ D +I K +RRY G + + +K + + E E+ R Y+ ++E+R K PN ++LE+ E+ + KSRAFY+MQATR TG GN++ + + + L + Q+IFF+P HYT+MENVG + VKR G + I ++Y TE+GTA DYI +G ++F+ E +K IEI ++DD+IFE +EHF + L + R ++GK E Y E+ + AT+++LDDDH G F FE + ESC + V R++GARG++ +PY TA DY+ + + F N++ I + IID +Y KD +F +ELG+P +++ KS P+ + + V ++I G P LG I +++ I ES FK VVD L++ LS+ I ++SWKEQF +A+TV G DS+D SE + P + +++H++T+FWKVLFAF+P
Sbjct: 2 IIRSTVYILALAYIFIGVSIISDKFMAAIERITSQEKEINLQIKADQAITIRVRVWNETVSNLTLMALGSSAPEIMLSVIEVCGKNFQSGALGPGTIVGSAAFNLFIIIGVCIAVVPDGEIRRIQQLNVFFVTATFSVIAYVWMYMILGVISVGIIEVWEAVLTFLLFPLTVVLAYLTDKRILSKLCSGGCRRRY-----------GPNRILM-----------EKDDEILEFEQLRASYMVTLQEMRKKYPNARLQSLEKMTLTEIFEKAKKSRAFYKMQATRMFTGGGNLVHHGISKLKTVSIEECLSGSIADERLQRIFFEPCHYTIMENVGIVKIFVKRAG---GYLGSSILIDYETEEGTALPDSDYIHAAGTLIFKPYEIEKIIEIKVVDDEIFEEEEHFTVRLFNLRV--KNGK--------ENFSYIYEISKMNRATVLILDDDHCGTFGFEADIMHIEESCNILTLNVYRNTGARGIIKIPYTIMDGTAKADVDYVTLGRKVVFKNEEIFKTISIKIIDGAQYSKDNFFFVELGQPKVIE-----KSTNPE-----------RKDKRRFVRSRADIATKGLPTLGSISIVQIHIHESSSFKSVVDKLIKQNNLSKSISSTSWKEQFTDALTVYGG-----DSEDGSESE-PQLISFILHYITVFWKVLFAFIP 626
BLAST of slc8a-1 vs. Planmine SMEST
Match: SMESG000050855.1 (SMESG000050855.1) HSP 1 Score: 475.707 bits (1223), Expect = 8.204e-152 Identity = 285/517 (55.13%), Postives = 374/517 (72.34%), Query Frame = 2
Query: 437 CESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYA-----LEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKKSKLERRLSQDPDKLGLKEKENNN--QKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGAR 1966
C + T C GI+LP W+P+HG S KI++A +Y + YLFLGVSII+DRFMA+IEVITSKE+ V V+K +G + + VR+WNETVSNLTLMALGSSAPEILLS+IEI G NF++G+LGPGTIVGSAA+NLF+IIG CV +IPDGEV++IKHLSVF+IT WS+FAY+WLYLI+A S V+++WEALLT FF LTV TAYVADTK+F KFLKRR++R N+K+ +EG N+ LED ++ KEN + EK R++Y+++I+EIRL+ PNID + LEE AQ E+L R KSRAFYR+QATR LTGS VI+KS +E L +D +K+ K K+++N Q+IFFDPGHYTV+EN+GT V++KR+G I T EVE+ ++DGTA+A +DYI G ++F G+ + I ++IIDDD+FE DEHF+I LK+ G+K L Q I+ +L P ATIM+LDDDH G+F+F + V E+ G EIKV RS+ R
Sbjct: 38 CFPDSKTDCADGIILPAWRPIHGNSNWFKISKATIYLFVMCYLFLGVSIISDRFMAAIEVITSKEKSVKVKKHDGTSELVKVRVWNETVSNLTLMALGSSAPEILLSIIEIIGKNFQSGELGPGTIVGSAAYNLFVIIGLCVLIIPDGEVKKIKHLSVFIITGLWSIFAYLWLYLILAKISVGVVEIWEALLTLAFFPLTVFTAYVADTKLFFNKFLKRRFIRNNIKTITQNTGDIEGSLTCTENYGLEDGNI--CDKENFGDFEKHRLEYLDIIKEIRLQQPNIDSRKLEELAQYEILKRSSKSRAFYRIQATRILTGSKFVIQKSNIESDLQKDFEKILCKSKKDDNIFQQIFFDPGHYTVLENIGTMQVLLKRSG--PLIENTFAEVEFYSKDGTASAHEDYIPVMGKLVFLPGQSEATINVTIIDDDVFEEDEHFYIELKNLIVYRVVGEK-----LKSQEIFPSQLANPSTATIMILDDDHPGVFHFGFSSITVPETIGMLEIKVYRSTAGR 545 HSP 2 Score: 385.185 bits (988), Expect = 8.651e-118 Identity = 216/478 (45.19%), Postives = 285/478 (59.62%), Query Frame = 2
Query: 1862 DDDHAGIFNFEEAETVVAESCGEAEIKVCRSSGA--RGVVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILVKKPG-------IGKSNIPKEFT----------------GFNHVS--------EVKTHSDQLVSQSSE----IEDMG----------------------------KPRLGDIKEIKVIIKESLEFKHVVDNLLRHGQLSEFIGTSSWKEQFVEAITVSPGENDTEDSDDLSEEKLPSCLDYVMHFLTLFWKVLFAFVPPTDYLGGWVSFWVCIVVIGALTAVIGDLASGFGCTIGMTNAVTAITFVAMGTSLPDTFASKVAAINDDSADSSVGNVTGSNAVNVFLGIGLAWSIAAVYHFFKGSTFRVKSGSLGFSVTVFCIFALTAIAFMLLRRNRRVGGELGGPRHLKIATTIYFVGLWIVYVILSSLENYCHIKGF 3100
DD+ F+ V E+ G ++ + RS V + S+ TA+ DYI V L F+ Q+EA I V IIDD+ +E+DE+F+IEL I+ + G I S + T GF+ ++ E+K + +SS IED G KP++ D I++ I+ES E KHVVD L+R +S+ +GTSSWKEQF EA+TV G DD++ K P Y+MH+L++FWK+LFA VPPT+ GGW+ FW I++IG LTA++GD+ASGFGC +G+T++VTAITFVA+GTSLPDTFASKVAA+ D +ADSSVGNV GSNAVNV+LGIG++WSIAA YH+ GS F+V+SGSLGFSVT+FCI A AIA ML RR +GGELGGP+ KI T F +W +Y++LSSLENYCHI GF
Sbjct: 382 DDNIFQQIFFDPGHYTVLENIGTMQVLLKRSGPLIENTFAEVEFYSKDGTASAHEDYIPVMGKLVFLPGQSEATINVTIIDDDVFEEDEHFYIELKNLIVYRVVGEKLKSQEIFPSQLANPSTATIMILDDDHPGVFHFGFSSITVPETIGMLEIKVYRSTAGRKSSNPLNLIEDFGRRLSFSRRNSKSNQVNLLEVKKTSNNECKPKIKDNNTIEICIRESQELKHVVDQLMRKSHISQILGTSSWKEQFKEALTVVSG-------DDVN--KSPQAGTYLMHYLSVFWKLLFACVPPTELCGGWLCFWFSILIIGILTAIVGDVASGFGCNVGLTDSVTAITFVALGTSLPDTFASKVAALQDSTADSSVGNVMGSNAVNVYLGIGISWSIAACYHYANGSIFKVESGSLGFSVTLFCIMAFIAIAIMLYRRKPSIGGELGGPKKSKIFTAFLFFSMWFIYILLSSLENYCHIPGF 850
BLAST of slc8a-1 vs. Planmine SMEST
Match: SMESG000041864.1 (SMESG000041864.1) HSP 1 Score: 375.555 bits (963), Expect = 1.423e-118 Identity = 232/509 (45.58%), Postives = 325/509 (63.85%), Query Frame = 2
Query: 440 ESLNDTSCKKGIVLPLWKPVHGLSIGDKIARAFVYFVSLMYLFLGVSIIADRFMASIEVITSKERKVIVRKKNGEMQTINVRIWNETVSNLTLMALGSSAPEILLSVIEICGSNFEAGDLGPGTIVGSAAFNLFIIIGYCVYVIPDGEVRRIKHLSVFLITASWSVFAYIWLYLIIAFFSPEVIQVWEAXXXXXXXXXXXXXAYVADTKIFIKKFLKRRYLRKNVKSYALEGDHELHCNHSLEDAHLDGDKKENLTELEKTRMDYIEVIREIRLKNPNIDPKTLEEQAQIEVLNRVPKSRAFYRMQATRTLTGSGNVIKK--SKLERRLSQDPDKLGLKEKENNNQKIFFDPGHYTVMENVGTFNVMVKRTGTDEQIAKTMIEVEYCTEDGTATAGDDYIATSGVVLFQSGEDQKPXXXXXXXXXXXXXXXXXXXNLKSPRAVTQDGKKVSINQLTEQNIYGVELIEPFIATIMVLDDDHAGIFNFEEAETVVAESCGEAEIKVCRSSG 1960
E N++ C +G+++P+W PV + D + R+ +Y +L Y+FLGVSII+DRFMASIE ITS+E+ V + KNG+ I VR+WNETVSNLTLMALGSSAPEI+LSVIE CG +F++G LGPGTIVGSAAFNLFIII C+ VIPDGE +RI ++ VF+IT+++S+ AY+WLYLI+ S +I+VWEA++TF F +TV+ AY+ D ++ KFL RK +E D E++ E E R +Y+ +E+RLK+P D + LE E+ + KSRAFY+MQATR LTG GN+ + SKL+ ++ + + + + Q+IFFDP HYTVME+ G V+VKR G + + ++Y TEDGTA AG DYI SG ++F++ E +K I I +IDD+++E E F + L + V +G+K S+N Y E+ + ATIM+LDDDH G FNFE + ESCG + + R++G
Sbjct: 9 ECYNNSKCVEGLIIPIWNPVE-IEFADTVIRSVIYIFALCYIFLGVSIISDRFMASIERITSEEKDVELVMKNGQKVNIKVRVWNETVSNLTLMALGSSAPEIMLSVIETCGKDFQSGSLGPGTIVGSAAFNLFIIIAICISVIPDGESKRIDNIGVFIITSTFSIVAYVWLYLILGVISQGIIEVWEAVITFLLFPITVMLAYMTDRQV-CSKFLNACLRRKGPVKIRMEYD-------------------EDIEEFEHLRENYMTTFKEMRLKHPTADVQNLELMTITEIFEKSKKSRAFYKMQATRMLTGGGNLFRNSLSKLKTNFLEESNSGSIADSK--LQRIFFDPVHYTVMEDAGQIQVIVKRAG---GFMGSTVFIDYKTEDGTALAGIDYIECSGTLVFKANESEKEISIDVIDDEVYEDQEFFTVLLFN--LVVINGQK-SLN-------YQYEVSKVNRATIMILDDDHCGTFNFETDIAHINESCGSVMVGITRTTG 481 HSP 2 Score: 55.0694 bits (131), Expect = 2.586e-7 Identity = 29/91 (31.87%), Postives = 48/91 (52.75%), Query Frame = 2
Query: 1889 FEEAETVVAESCGEAEIKVCRSSGARG-VVLVPYRSRSDTATGGTDYIEVESYLEFMNDQTEAFIKVNIIDDNEYEKDEYFHIELGEPILV 2158
F+ V E G+ ++ V R+ G G V + Y++ TA G DYIE L F +++E I +++IDD YE E+F + L +++
Sbjct: 335 FDPVHYTVMEDAGQIQVIVKRAGGFMGSTVFIDYKTEDGTALAGIDYIECSGTLVFKANESEKEISIDVIDDEVYEDQEFFTVLLFNLVVI 425 The following BLAST results are available for this feature:
BLAST of slc8a-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc8a-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc8a-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of slc8a-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc8a-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc8a-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30029327 ID=SMED30029327|Name=slc8a-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3407bpback to top protein sequence of SMED30029327-orf-1 >SMED30029327-orf-1 ID=SMED30029327-orf-1|Name=SMED30029327-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=918bp MRGNLLFGSCIVVIEFLSWIQCEPLKNGACESLNDTSCKKGIVLPLWKPVback to top Aliases
The feature 'slc8a-1' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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