Potassium voltage-gated channel protein Shal-like Protein

Overview
NamePotassium voltage-gated channel protein Shal-like Protein
Smed IDSMED30029282
Length (bp)2318
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Potassium voltage-gated channel protein Shal-like Protein (SMED30029282) t-SNE clustered cells

Violin plots show distribution of expression levels for Potassium voltage-gated channel protein Shal-like Protein (SMED30029282) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Potassium voltage-gated channel protein Shal-like Protein (SMED30029282) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Potassium voltage-gated channel protein Shal-like Protein (SMED30029282) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30029282

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30029282h1SMcG0021860 SmedASXL_001248SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30029282h1SMcG0021860 Contig22188newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30029282h1SMcG0021860 dd_Smed_v4_15876_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30029282h1SMcG0021860 dd_Smed_v4_15876_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029282h1SMcG0021860 Contig52830uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029282h1SMcG0021860 Contig52830newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30029282h1SMcG0021860 dd_Smed_v6_15876_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
neuronSMED30029282h1SMcG0021860 Contig52830uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
neuronSMED30029282h1SMcG0021860 Contig52830newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Human
Match: KCND1 (potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 310/495 (62.63%), Postives = 379/495 (76.57%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDR----KLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNAN-TNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSEND--EDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+PL    LP P       R +E + +NVSG +FETWKNTLD+Y DTLLGS EK++FYD    EYFFDRDPD+FR++L++Y+TG+LHCP+ EC+ A+D+EL+F+G++P+++GDCC E+YRD+++EN +R  ED EAE       LP   ++R++LWRAF+NP TS AALVFYYVTGFFIAVSV+ANVVETI C  +A  ++  + CGE + +AFFC+DTACVLIFT EYL RL+AAP R +F+RS+MSLIDVVAILPYYIGLL+ KN+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK   KT FTSIPA+FWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQQK R ARI LAK+     F               LQ+ +N   ED    ++  +     +  E QHHHLL CLE  T  E  D+
Sbjct:   18 GWLPLAQQPLP-PAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAF---------------LQYKQNGGLEDSGSGEEQALCVRNRSAFEQQHHHLLHCLEKTTCHEFTDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Human
Match: KCND2 (potassium voltage-gated channel subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:6238])

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 303/491 (61.71%), Postives = 382/491 (77.80%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDRE---AEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ +  +P P  QE     +  + +NVSG +F+TW++TL++Y DTLLGS E+D+FY    ++YFFDRDPDIFR+IL++Y+TGKLH P+HEC+SAYD+EL+FFG++P+I+GDCCYE+Y+D++REN +R  +D +   A +  LP + T R+++WRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C  +    +   CGE Y  AFFCLDTACV+IFT+EYL RL AAP R +FVRS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI  AK+ +   ++++K         N LQ SE+++ +     S+         E QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTM-TARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNG---LLSNQLQSSEDEQAFVSKSGSS--------FETQHHHLLHCLEKTTNHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Human
Match: KCND3 (potassium voltage-gated channel subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:6239])

HSP 1 Score: 551.206 bits (1419), Expect = 0.000e+0
Identity = 304/508 (59.84%), Postives = 394/508 (77.56%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESDNQSSIRDSYSS 1625
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR +L++Y+TGKLH P++EC+SAYDDEL+F+GILP+I+GDCCYE+Y+D++REN +R ++D ++E+ +  +P L + R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C     + E   CGE Y  AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  +   ++ +        KRN L +   +   T +++    G   +L+E QHHHLL CLE  T  E +D+ + +E +   S   +Y S
Sbjct:   18 GWMPVANCPMPL-APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL-SFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELP-CGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHS--------KRNGLLNEALELTGTPEEEH--MGKTTSLIESQHHHLLHCLEKTTNHEFIDE-QMFEQNCMESSMQNYPS 511          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Human
Match: KCND3 (potassium voltage-gated channel subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:6239])

HSP 1 Score: 551.206 bits (1419), Expect = 0.000e+0
Identity = 304/508 (59.84%), Postives = 394/508 (77.56%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESDNQSSIRDSYSS 1625
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR +L++Y+TGKLH P++EC+SAYDDEL+F+GILP+I+GDCCYE+Y+D++REN +R ++D ++E+ +  +P L + R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C     + E   CGE Y  AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  +   ++ +        KRN L +   +   T +++    G   +L+E QHHHLL CLE  T  E +D+ + +E +   S   +Y S
Sbjct:   18 GWMPVANCPMPL-APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL-SFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELP-CGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHS--------KRNGLLNEALELTGTPEEEH--MGKTTSLIESQHHHLLHCLEKTTNHEFIDE-QMFEQNCMESSMQNYPS 511          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Human
Match: KCND3 (potassium voltage-gated channel subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:6239])

HSP 1 Score: 549.28 bits (1414), Expect = 0.000e+0
Identity = 303/491 (61.71%), Postives = 387/491 (78.82%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRE-LVDD 1571
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR +L++Y+TGKLH P++EC+SAYDDEL+F+GILP+I+GDCCYE+Y+D++REN +R ++D ++E+ +  +P L + R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C     + E   CGE Y  AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  +   ++ +        KRN L +   +   T +++    G   +L+E QHHHLL CLE  TG   LVDD
Sbjct:   18 GWMPVANCPMPL-APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL-SFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELP-CGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHS--------KRNGLLNEALELTGTPEEEH--MGKTTSLIESQHHHLLHCLEKTTGLSYLVDD 495          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Celegans
Match: shl-1 (SHaL family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q95XD1])

HSP 1 Score: 547.354 bits (1409), Expect = 0.000e+0
Identity = 307/505 (60.79%), Postives = 386/505 (76.44%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQ------ETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLK-TIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESDNQS 1601
            GWVP++   +P+  +         DH S+EK+ IN+SG +FETWKNTL+K+ +TLLGS+EK++FYDE   EYFFDRDPDIFR+IL++Y+TGKLH P+HEC+ AYD+ELSFFGI+PD++ DCCYEDY+DK+REN +R  E+R  E+  +  LK +++EK+W AF+NP T+  ALVFYYV GFFIAVSV+ N+VETI C +  N   S TCGE YE+ FF +DTACV+IFT+EY  RL +AP R+KF+RSIMS+IDV+AI+PYY+ L+++ N D+SG FV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFL+FSL+MA+IIFAT++YYAEK    T FTSIP++FWYTIVT+TTLGYGDM P T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI + KN +      NK +A E R     Q        ++D   +     E + EIQHHHLL CLE  T RE V+    +E    +
Sbjct:   17 GWVPISRQPMPQAPVAIQAKDLAVDHVSDEKLAINISGRRFETWKNTLEKFPETLLGSNEKEFFYDEDTGEYFFDRDPDIFRHILTFYRTGKLHYPRHECLVAYDEELSFFGIMPDLISDCCYEDYKDKKRENQERLQEER-VENADISTLKLSLKEKMWAAFENPHTTSIALVFYYVIGFFIAVSVMCNIVETIPCGYEDNV--SVTCGEAYEEQFFVIDTACVIIFTIEYFLRLISAPDRIKFMRSIMSVIDVIAIMPYYVSLVLTDNKDVSGLFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATIMYYAEKKVDATRFTSIPSAFWYTIVTLTTLGYGDMVPSTIMGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKARLARIRIVKNASGLALF-NKKRAHEARMLAFEQGH-----LSFDALRD-----EDIFEIQHHHLLQCLEKATEREFVESEVMFEGGRNT 507          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 193.356 bits (490), Expect = 4.878e-54
Identity = 117/371 (31.54%), Postives = 209/371 (56.33%), Query Frame = 3
Query:  114 VPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGS-DEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNA----NTNESKTCGETYEK---AFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLIS----KNNDMSGAFVILRVFRVFRII-KFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTP 1184
            +P      P  +  +    +++ V INVSG +F+T+++TL +Y ++LLG  +++ +F+     E+FFDR    F  IL  YQ+G ++  P+   +  +  E+ FF      MGD   E++     E +++       ++  +P  KT R K+W   + P +S++A +  +++   IA+S+++   ET+  D       N+  ++   E  EK    FF ++  C+L FT+E + R  + P ++ F  S++++ID VAI P+++    +     N+ MS A + +        + K SRHS+GL+ILG T +S   E   L+F +++A+++FA+ +Y+AE+ +  + FTSIPASFW+ +VTMTT+GYGD+ P
Sbjct:   23 LPSPQRGTPDTSSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQ-----MGDDLLEEFWIA--EGYEK------PKEVMMPNNKTQR-KIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNFFFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVP 379          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 193.356 bits (490), Expect = 4.878e-54
Identity = 117/371 (31.54%), Postives = 209/371 (56.33%), Query Frame = 3
Query:  114 VPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGS-DEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNA----NTNESKTCGETYEK---AFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLIS----KNNDMSGAFVILRVFRVFRII-KFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTP 1184
            +P      P  +  +    +++ V INVSG +F+T+++TL +Y ++LLG  +++ +F+     E+FFDR    F  IL  YQ+G ++  P+   +  +  E+ FF      MGD   E++     E +++       ++  +P  KT R K+W   + P +S++A +  +++   IA+S+++   ET+  D       N+  ++   E  EK    FF ++  C+L FT+E + R  + P ++ F  S++++ID VAI P+++    +     N+ MS A + +        + K SRHS+GL+ILG T +S   E   L+F +++A+++FA+ +Y+AE+ +  + FTSIPASFW+ +VTMTT+GYGD+ P
Sbjct:   23 LPSPQRGTPDTSSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQ-----MGDDLLEEFWIA--EGYEK------PKEVMMPNNKTQR-KIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNFFFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVP 379          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 193.356 bits (490), Expect = 5.442e-54
Identity = 116/371 (31.27%), Postives = 206/371 (55.53%), Query Frame = 3
Query:  114 VPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGS-DEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNA----NTNESKTCGETYEK---AFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLIS----KNNDMSGAFVILRVFRVFRII-KFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTP 1184
            +P      P  +  +    +++ V INVSG +F+T+++TL +Y ++LLG  +++ +F+     E+FFDR    F  IL  YQ+G ++  P+   +  +  E+ FF      MGD   E++   +     + +         +P  KT R K+W   + P +S++A +  +++   IA+S+++   ET+  D       N+  ++   E  EK    FF ++  C+L FT+E + R  + P ++ F  S++++ID VAI P+++    +     N+ MS A + +        + K SRHS+GL+ILG T +S   E   L+F +++A+++FA+ +Y+AE+ +  + FTSIPASFW+ +VTMTT+GYGD+ P
Sbjct:   36 LPSPQRGTPDTSSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQ-----MGDDLLEEFWIAEGYEKPKEV--------MMPNNKTQR-KIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNFFFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVP 392          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 193.741 bits (491), Expect = 1.000e-53
Identity = 115/371 (31.00%), Postives = 207/371 (55.80%), Query Frame = 3
Query:  114 VPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGS-DEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNA----NTNESKTCGETYEK---AFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLIS----KNNDMSGAFVILRVFRVFRII-KFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTP 1184
            +P      P  +  +    +++ V INVSG +F+T+++TL +Y ++LLG  +++ +F+     E+FFDR    F  IL  YQ+G ++  P+   +  +  E+ FF +  D++ +    +  +K +E               +P  KT R K+W   + P +S++A +  +++   IA+S+++   ET+  D       N+  ++   E  EK    FF ++  C+L FT+E + R  + P ++ F  S++++ID VAI P+++    +     N+ MS A + +        + K SRHS+GL+ILG T +S   E   L+F +++A+++FA+ +Y+AE+ +  + FTSIPASFW+ +VTMTT+GYGD+ P
Sbjct:   69 LPSPQRGTPDTSSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVM-------------MPNNKTQR-KIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNFFFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVP 425          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Fly
Match: Shal (gene:FBgn0005564 transcript:FBtr0112853)

HSP 1 Score: 569.696 bits (1467), Expect = 0.000e+0
Identity = 319/490 (65.10%), Postives = 392/490 (80.00%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSE-EKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE--DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVD 1568
            GWVP+  H LP P + +   +++ EK+ INVSG +FETW+NTL+KY DTLLGS+E+++FYDE  KEYFFDRDPDIFR+IL+YY+TGKLH PKHEC+++YD+EL+FFGI+PD++GDCCYEDYRD++REN +R ++D+ +E  D+ L  L  +R+K+WRAF+NP TS +ALVFYYVTGFFIAVSV+ANVVET+ C        +  CGE Y+  FFCLDTACV+IFT EYL RL+AAP R KFVRS+MS+IDVVAI+PYYIGL I+ N+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFL+FSL+MA+IIFAT+++YAEK+   T FTSIPA+FWYTIVTMTTLGYGDM P+T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI +AK  +   F+  K  A+ R      Q S  + D  Y          E + E+QHHHLL CLE  T RE V+
Sbjct:   17 GWVPIATHPLPPPPMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLGSNEREFFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARW---AAQESGIELDDNYR--------DEDIFELQHHHLLRCLEKTTDREFVE 495          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Fly
Match: Shal (gene:FBgn0005564 transcript:FBtr0333273)

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 320/509 (62.87%), Postives = 397/509 (78.00%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSE-EKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE--DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVT--GRELVDDTRQYESDNQSSIRDSY 1619
            GWVP+  H LP P + +   +++ EK+ INVSG +FETW+NTL+KY DTLLGS+E+++FYDE  KEYFFDRDPDIFR+IL+YY+TGKLH PKHEC+++YD+EL+FFGI+PD++GDCCYEDYRD++REN +R ++D+ +E  D+ L  L  +R+K+WRAF+NP TS +ALVFYYVTGFFIAVSV+ANVVET+ C        +  CGE Y+  FFCLDTACV+IFT EYL RL+AAP R KFVRS+MS+IDVVAI+PYYIGL I+ N+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFL+FSL+MA+IIFAT+++YAEK+   T FTSIPA+FWYTIVTMTTLGYGDM P+T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI +AK  +   F+  K  A+ R      Q S  + D  Y          E + E+QHHHLL CLE  T  G+ +   +    S N   +  +Y
Sbjct:   17 GWVPIATHPLPPPPMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLGSNEREFFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARW---AAQESGIELDDNYR--------DEDIFELQHHHLLRCLEKTTACGKYMPAASNAQNSQNNQPMDGTY 514          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Fly
Match: Shal (gene:FBgn0005564 transcript:FBtr0074973)

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 316/484 (65.29%), Postives = 389/484 (80.37%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSE-EKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE--DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVT 1550
            GWVP+  H LP P + +   +++ EK+ INVSG +FETW+NTL+KY DTLLGS+E+++FYDE  KEYFFDRDPDIFR+IL+YY+TGKLH PKHEC+++YD+EL+FFGI+PD++GDCCYEDYRD++REN +R ++D+ +E  D+ L  L  +R+K+WRAF+NP TS +ALVFYYVTGFFIAVSV+ANVVET+ C        +  CGE Y+  FFCLDTACV+IFT EYL RL+AAP R KFVRS+MS+IDVVAI+PYYIGL I+ N+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFL+FSL+MA+IIFAT+++YAEK+   T FTSIPA+FWYTIVTMTTLGYGDM P+T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI +AK  +   F+  K +A E R        E D++Y            E + E+QHHHLL CLE  T
Sbjct:   17 GWVPIATHPLPPPPMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLGSNEREFFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKK-KAAEARWAAQESGIELDDNYR----------DEDIFELQHHHLLRCLEKTT 489          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0302903)

HSP 1 Score: 230.72 bits (587), Expect = 1.244e-65
Identity = 156/411 (37.96%), Postives = 234/411 (56.93%), Query Frame = 3
Query:  162 DHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDY-FYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQR--ENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETIS-----CDFNANTNESKTCGETYEK---AFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLI---------------------SKNNDMSGAFV-ILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYH 1292
            DH   E+V INVSG +FET   TL+++ DTLLG   +   ++D +  EYFFDR    F  IL YYQ+G +L  P +  +  + +E+ F+      +GD     +R+ +   +  +R + D E +            K+W  F+ P++S AA V   ++ F I +S++   +ET+        FN  TN +K   +        FF ++T C++ FT E   R  A P ++ F R +M++ID++AI+PY+I L                       S N  MS A + ++R+ RVFRI K SRHS GL+ILG TLK+   ELG L+F L + V++F++ +Y+AE     + F SIP +FW+ +VTMTT+GYGDMTP  V GK++G +C+++G+L IALPVPVIVSNF+  YH
Sbjct:   80 DHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYE-----LGDQAINKFREDEGFIKEEERPLPDNEKQ-----------RKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 474          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089661)

HSP 1 Score: 230.72 bits (587), Expect = 1.244e-65
Identity = 156/411 (37.96%), Postives = 234/411 (56.93%), Query Frame = 3
Query:  162 DHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDY-FYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQR--ENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETIS-----CDFNANTNESKTCGETYEK---AFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLI---------------------SKNNDMSGAFV-ILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYH 1292
            DH   E+V INVSG +FET   TL+++ DTLLG   +   ++D +  EYFFDR    F  IL YYQ+G +L  P +  +  + +E+ F+      +GD     +R+ +   +  +R + D E +            K+W  F+ P++S AA V   ++ F I +S++   +ET+        FN  TN +K   +        FF ++T C++ FT E   R  A P ++ F R +M++ID++AI+PY+I L                       S N  MS A + ++R+ RVFRI K SRHS GL+ILG TLK+   ELG L+F L + V++F++ +Y+AE     + F SIP +FW+ +VTMTT+GYGDMTP  V GK++G +C+++G+L IALPVPVIVSNF+  YH
Sbjct:   80 DHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYE-----LGDQAINKFREDEGFIKEEERPLPDNEKQ-----------RKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 474          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Zebrafish
Match: kcnd3 (potassium voltage-gated channel, Shal-related subfamily, member 3 [Source:ZFIN;Acc:ZDB-GENE-030131-5626])

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 312/500 (62.40%), Postives = 389/500 (77.80%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQET-DHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDRE-AEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXX--XXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHS-ENDEDYTYDKQSNINGVKET--LLEIQHHHLLSCLEMVTGRELVDDTRQYE 1586
            GW+P+ N  LP P      + R +E + +NVSG +F+TW+NTLD+Y DTLLGS EK++F++E  +EYFFDRDPD+FR IL++Y+TGKLH P++EC+SAYD+EL+FFGI+P+I+ DCCYE+Y+D++REN +R ++D E  +D KLP + T RE +WRAF+NP TS  ALVFYYVTGFFIA+SV+ NVVET+ C +  N  +   CGE Y +AFFC+DTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRA   K +  QKAR AR+ ++K+ + T F+ +        KRN L  S E       D+Q     +K+T  LLE QHHHLL CLE  T  E VD+ R YE
Sbjct:   18 GWMPVAN--LPMPVAPSNKNKRQDELIILNVSGRRFQTWRNTLDRYPDTLLGSSEKEFFFNEETREYFFDRDPDVFRSILNFYRTGKLHYPRYECISAYDEELAFFGIIPEIISDCCYEEYKDRKRENTERLMDDLEDNKDSKLPNM-TFRETMWRAFENPHTSTMALVFYYVTGFFIALSVITNVVETVPCGYMPNQRDVP-CGERYTEAFFCMDTACVMIFTVEYLMRLFAAPSRYRFMRSVMSIIDVVAILPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKVQKARLARMRISKSGSSTAFLHS--------KRNGLNQSLELTGSLEEDQQ-----LKKTTSLLESQHHHLLHCLEKTTNHEFVDE-RLYE 499          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Zebrafish
Match: kcnd3 (potassium voltage-gated channel, Shal-related subfamily, member 3 [Source:ZFIN;Acc:ZDB-GENE-030131-5626])

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 311/507 (61.34%), Postives = 388/507 (76.53%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQET-DHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDRE-AEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXX--XXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQ--SNINGVKE--------TLLEIQHHHLLSCLEMVTGRELVDDTRQYE 1586
            GW+P+ N  LP P      + R +E + +NVSG +F+TW+NTLD+Y DTLLGS EK++F++E  +EYFFDRDPD+FR IL++Y+TGKLH P++EC+SAYD+EL+FFGI+P+I+ DCCYE+Y+D++REN +R ++D E  +D KLP + T RE +WRAF+NP TS  ALVFYYVTGFFIA+SV+ NVVET+ C +  N  +   CGE Y +AFFC+DTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRA   K +  QKAR AR+ ++K+ + T F+ +        KRN L  S       Y K   S    ++E        +LLE QHHHLL CLE  T  E VD+ R YE
Sbjct:   18 GWMPVAN--LPMPVAPSNKNKRQDELIILNVSGRRFQTWRNTLDRYPDTLLGSSEKEFFFNEETREYFFDRDPDVFRSILNFYRTGKLHYPRYECISAYDEELAFFGIIPEIISDCCYEEYKDRKRENTERLMDDLEDNKDSKLPNM-TFRETMWRAFENPHTSTMALVFYYVTGFFIALSVITNVVETVPCGYMPNQRDVP-CGERYTEAFFCMDTACVMIFTVEYLMRLFAAPSRYRFMRSVMSIIDVVAILPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKVQKARLARMRISKSGSSTAFLHS--------KRNGLNQSLELTQLPYYKMKLSPQGSLEEDQQLKKTTSLLESQHHHLLHCLEKTTNHEFVDE-RLYE 511          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Zebrafish
Match: kcnd2 (potassium voltage-gated channel, Shal-related subfamily, member 2 [Source:ZFIN;Acc:ZDB-GENE-041210-70])

HSP 1 Score: 547.354 bits (1409), Expect = 0.000e+0
Identity = 301/497 (60.56%), Postives = 381/497 (76.66%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLK--TIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESD 1592
            GW+P+ +  +P P  ++     +  + +NVSG +F+TW+NTL++Y DTLLGS E+D+F+ E   EYFFDRDPDIFR+IL++Y+TGKLH P+HEC+SAYD+EL+FFGI+P+I+GDCCYE+Y+D++REN +R  +D E ++    V+   + RE +WRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C  + N  +  +CGE Y  AFFCLDTACV+IFT+EYL RL AAP R KFV+S+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQ+QRA+KR+AQ+K R ARI  AK+     +++         KRN +     +E      Q+ +     T  E QHHHLL CLE  T  E VD+ + YE+ 
Sbjct:   18 GWMPVASAPMPPPP-RDKKRGQDGLIILNVSGTRFQTWRNTLERYPDTLLGSTERDFFFHEETNEYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGIIPEIIGDCCYEEYKDRRRENAERIQDDEENDNNNDLVMPDLSFRESMWRAFENPHTSTMALVFYYVTGFFIAVSVMANVVETVPCGISLNRAKELSCGERYALAFFCLDTACVMIFTVEYLLRLIAAPSRYKFVKSVMSIIDVVAIMPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSAGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIMGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQSQRAEKRRAQKKTRLARIRAAKSGGANAYLQY--------KRNGMLVDMEEEASKEAGQALVCKANPT-FETQHHHLLHCLEKTTNHEFVDE-QTYETS 503          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Zebrafish
Match: kcnd2 (potassium voltage-gated channel, Shal-related subfamily, member 2 [Source:ZFIN;Acc:ZDB-GENE-041210-70])

HSP 1 Score: 547.354 bits (1409), Expect = 0.000e+0
Identity = 301/497 (60.56%), Postives = 381/497 (76.66%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLK--TIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESD 1592
            GW+P+ +  +P P  ++     +  + +NVSG +F+TW+NTL++Y DTLLGS E+D+F+ E   EYFFDRDPDIFR+IL++Y+TGKLH P+HEC+SAYD+EL+FFGI+P+I+GDCCYE+Y+D++REN +R  +D E ++    V+   + RE +WRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C  + N  +  +CGE Y  AFFCLDTACV+IFT+EYL RL AAP R KFV+S+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQ+QRA+KR+AQ+K R ARI  AK+     +++         KRN +     +E      Q+ +     T  E QHHHLL CLE  T  E VD+ + YE+ 
Sbjct:   18 GWMPVASAPMPPPP-RDKKRGQDGLIILNVSGTRFQTWRNTLERYPDTLLGSTERDFFFHEETNEYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGIIPEIIGDCCYEEYKDRRRENAERIQDDEENDNNNDLVMPDLSFRESMWRAFENPHTSTMALVFYYVTGFFIAVSVMANVVETVPCGISLNRAKELSCGERYALAFFCLDTACVMIFTVEYLLRLIAAPSRYKFVKSVMSIIDVVAIMPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSAGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIMGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQSQRAEKRRAQKKTRLARIRAAKSGGANAYLQY--------KRNGMLVDMEEEASKEAGQALVCKANPT-FETQHHHLLHCLEKTTNHEFVDE-QTYETS 503          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Zebrafish
Match: kcnd1 (potassium voltage-gated channel, Shal-related subfamily, member 1 [Source:ZFIN;Acc:ZDB-GENE-081105-40])

HSP 1 Score: 542.732 bits (1397), Expect = 0.000e+0
Identity = 291/432 (67.36%), Postives = 354/432 (81.94%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNK 1394
            GW+PL   ++PKP I + + R++E + +NVSG +F+TWKNTLD+Y DTLLGS EK++FY+E  +EYFFDRDP++FR+IL++Y+TG+LH P+ EC+ A+D+EL+F+GI+PDI+GDCC E+YRD+++EN +R   D EAE   D  LP   T RE+LWRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C     + +   CGE Y  AFFC+DTACVLIFT EYL RL+AAP R KF+RS+MS+IDVVAI+PYYIGL++ +N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    T FTSIPASFWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADK +AQQK R ARI LAK      F++ K
Sbjct:   18 GWLPLAKKTMPKPPIDKKN-RNDEILFVNVSGLRFQTWKNTLDRYPDTLLGSSEKEFFYNEDTQEYFFDRDPEMFRHILNFYRTGRLHYPRQECIQAFDEELAFYGIVPDIIGDCCMEEYRDRKKENQERLAVDTEAEMATDTPLPPHSTHRERLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCRPLKGSKKDLPCGEKYSLAFFCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSVIDVVAIMPYYIGLVMPENEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTKGTNFTSIPASFWYTIVTMTTLGYGDMVPNTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKMRAQQKVRLARIRLAKKGTTNAFLQYK 448          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Xenopus
Match: KCND2 (potassium voltage-gated channel subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:6238])

HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0
Identity = 298/489 (60.94%), Postives = 376/489 (76.89%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLK-TIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+    +P   + E     +  + +NVSG +F+TW+NTL++Y DTLLGS E+D+F+++   EYFFDRDPDIFR+IL++Y+TG+LH P+HEC+SAYD+EL+FFGI+P+I+GDCCYE+Y+D++REN +R ++D +    + P+   + R+K+WRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C  +  +     CGE Y  AFFCLDTACV+IFT+EYL RL AAP R +FVRS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK  L + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+K R ARI LAK+ +   ++++K           LQ S  +E     K         +    QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVAAGPMPPTPLGEKKRTQDSLIVLNVSGTRFQTWRNTLERYPDTLLGSTERDFFFNQDSGEYFFDRDPDIFRHILNFYRTGRLHYPRHECISAYDEELAFFGIIPEIIGDCCYEEYKDRRRENAERLLDDADENKAEGPLPPMSARQKMWRAFENPHTSTLALVFYYVTGFFIAVSVIANVVETVPCGISPGSLRELPCGERYALAFFCLDTACVMIFTVEYLLRLVAAPSRYRFVRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSLNSRFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKTRLARIRLAKSGSANAYLQSKRNG---LLNEALQGSSEEEQPLVSKSG-------STFATQHHHLLHCLEKTTNHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Xenopus
Match: kcnd3 (potassium channel, voltage gated Shal related subfamily D, member 3 [Source:NCBI gene;Acc:100125015])

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 307/504 (60.91%), Postives = 397/504 (78.77%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESDNQSSIRD 1613
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR IL++Y+TGKLH P++EC+SAYD+EL+F+GILP+I+GDCCYE+Y+D++REN +R ++D E E+ +  +P L T+R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C      N+   CGE Y+ AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  + T ++ +        KRN L + E  E     ++ +I G   +L+E QHHHLL CLE  T  E +D+    ++  +SS+++
Sbjct:   18 GWMPVANCPMPLAP-ADKNKRQDEVIILNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEETKEYFFDRDPEVFRCILNFYRTGKLHYPRYECISAYDEELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNEFENNQEAMPSL-TLRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCG-TVPGNKELPCGERYDVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFMRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSTAYLHS--------KRNGLLN-EALELMGSTEEPHI-GKSASLIESQHHHLLHCLEKTTNHEFMDEQMFEQNCRESSMQN 508          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Xenopus
Match: kcnd3 (potassium channel, voltage gated Shal related subfamily D, member 3 [Source:NCBI gene;Acc:100125015])

HSP 1 Score: 552.362 bits (1422), Expect = 0.000e+0
Identity = 308/491 (62.73%), Postives = 390/491 (79.43%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRE-LVDD 1571
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR IL++Y+TGKLH P++EC+SAYD+EL+F+GILP+I+GDCCYE+Y+D++REN +R ++D E E+ +  +P L T+R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C      N+   CGE Y+ AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  + T ++ +        KRN L + E  E     ++ +I G   +L+E QHHHLL CLE  TG   LVDD
Sbjct:   18 GWMPVANCPMPLAP-ADKNKRQDEVIILNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEETKEYFFDRDPEVFRCILNFYRTGKLHYPRYECISAYDEELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNEFENNQEAMPSL-TLRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCG-TVPGNKELPCGERYDVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFMRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSTAYLHS--------KRNGLLN-EALELMGSTEEPHI-GKSASLIESQHHHLLHCLEKTTGLSYLVDD 495          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Xenopus
Match: ENSXETT00000036803.1 (potassium channel, voltage gated Shal related subfamily D, member 1 [Source:NCBI gene;Acc:100488387])

HSP 1 Score: 540.806 bits (1392), Expect = 0.000e+0
Identity = 291/432 (67.36%), Postives = 355/432 (82.18%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNK 1394
            GW+PL    +PKP   +   +S+E + +NVSG KF+TWKNTLD+Y DTLLGS EKD+F+++  +EYFFDRDP++FR+IL++Y+TGKLH P+HEC+ A+D+ELSF+GI+P+I+GDCC E+YRD+++EN +R  ED EAE   D  LP   T R++LWRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C   A   +   CGE Y  AF C+DTACVLIFT EYL RL+AAP R KF+RS+MS+IDVVAI+P+YIGL++ +N ++SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK   KT FTSIPA+FWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQQK R ARI LAK+     F++ K
Sbjct:   18 GWLPLAKRPMPKPP-SDKRMKSDEILVVNVSGRKFQTWKNTLDRYPDTLLGSTEKDFFFNQDTQEYFFDRDPEMFRHILNFYRTGKLHYPRHECIQAFDEELSFYGIIPEIIGDCCLEEYRDRKKENLERLAEDTEAETAGDTPLPPDSTFRQRLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCRPPAGRLKELPCGEKYNLAFVCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSIIDVVAIMPFYIGLVMPENENVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTSKTKFTSIPAAFWYTIVTMTTLGYGDMVPDTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKIRLARIRLAKSNTTGAFLRYK 448          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Xenopus
Match: KCNA5 (potassium channel, voltage gated shaker related subfamily A, member 5 [Source:NCBI gene;Acc:496997])

HSP 1 Score: 241.121 bits (614), Expect = 3.632e-69
Identity = 161/402 (40.05%), Postives = 243/402 (60.45%), Query Frame = 3
Query:  162 DHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDY-FYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNE-----SKTCGETYE---------KAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLI------SKNNDMSGAFVILRVFR---VFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYH 1292
            DH S ++V IN++G +FET  +TL+++ DTLLG  EK   F+D +  EYFFDR+   F  IL +YQ+G K+  P +  +  + DE+ F+      +G+   E +R+ +    D        E++ LP     + ++W  F+ P++S +A     V+   I +S++   +ET+  +F  + NE     SK   +T E           FF ++T CV+ FT E L R +A P +  F ++IM++ID+VAI+PY+I L        + N   + +  ILRV R   VFRI K SRHS GL+ILG TLK+   ELG L+F L + VI+F++ +Y+AE  D ++ F+SIP +FW+ +VTMTT+GYGDM P TV GK++G +C+++G+L IALPVPVIVSNF+  YH
Sbjct:  164 DHESNQRVIINIAGLRFETQLSTLNQFPDTLLGDPEKRMRFFDPLRNEYFFDRNRPSFDGILYFYQSGGKIRRPVNVSIDVFADEIRFYE-----LGEEAMERFREDEGFIKD--------EEKPLPC-NEFQRQVWLIFEYPESSSSARGIAIVSVLVILISIITFCLETLP-EFR-DENELPPALSKVLNDTQEHPSPPSGLTDPFFIIETTCVIWFTFELLVRFFACPSKSDFSKNIMNIIDIVAIIPYFITLGTELAQHQTNNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPESHFSSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 549          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Mouse
Match: Kcnd1 (potassium voltage-gated channel, Shal-related family, member 1 [Source:MGI Symbol;Acc:MGI:96671])

HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0
Identity = 306/493 (62.07%), Postives = 378/493 (76.67%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDR----KLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNAN-TNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+PL    LP P  +    R +E + +NVSG +FETWKNTLD+Y DTLLGS EK++FYD    EYFFDRDPD+FR++L++Y+TG+LHCP+ EC+ A+D+EL+F+G++P+++GDCC E+YRD+++EN +R  ED EAE       LP   ++R++LWRAF+NP TS AALVFYYVTGFFIAVSV+ANVVETI C       ++ ++CG+ +  AFFC+DTACVLIFT EYL RL+AAP R +F+RS+MSLIDVVAILPYYIGL + KN+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK   KT FTSIPA+FWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQQK R ARI LAK+     F++ K       +   L+ S + +      +S       +  E QHHHLL CLE  T  E  D+
Sbjct:   18 GWLPLAQQPLP-PAPEVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDAESGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGEGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGTPRWPSKEQSCGDRFPTAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTSKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYK-------QNGGLEDSGSGDGQMLCVRS------RSAFEQQHHHLLHCLEKTTCHEFTDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Mouse
Match: Kcnd2 (potassium voltage-gated channel, Shal-related family, member 2 [Source:MGI Symbol;Acc:MGI:102663])

HSP 1 Score: 556.214 bits (1432), Expect = 0.000e+0
Identity = 302/491 (61.51%), Postives = 381/491 (77.60%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ +  +P P  QE     +  + +NVSG +F+TW++TL++Y DTLLGS E+D+FY    ++YFFDRDPDIFR+IL++Y+TGKLH P+HEC+SAYD+EL+FFG++P+I+GDCCYE+Y+D++REN +R  +D + +   +  LP + T R+++WRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C  +    +   CGE Y  AFFCLDTACV+IFT+EYL RL AAP R +FVRS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI  AK+ +   ++++K         N LQ SE++  +     S+         E QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDNTGESALPTM-TARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNG---LLSNQLQSSEDEPAFISKSGSS--------FETQHHHLLHCLEKTTNHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Mouse
Match: Kcnd3 (potassium voltage-gated channel, Shal-related family, member 3 [Source:MGI Symbol;Acc:MGI:1928743])

HSP 1 Score: 551.977 bits (1421), Expect = 0.000e+0
Identity = 304/508 (59.84%), Postives = 394/508 (77.56%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESDNQSSIRDSYSS 1625
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR +L++Y+TGKLH P++EC+SAYDDEL+F+GILP+I+GDCCYE+Y+D++REN +R ++D ++E+ +  +P L + R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C     + E   CGE Y  AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  +   ++ +        KRN L +   +   T +++    G   +L+E QHHHLL CLE  T  E +D+ + +E +   S   +Y S
Sbjct:   18 GWMPVANCPMPL-APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL-SFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELP-CGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHS--------KRNGLLNEALELTGTPEEEQ--MGKTTSLIESQHHHLLHCLEKTTNHEFIDE-QMFEQNCMESSMQNYPS 511          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Mouse
Match: Kcnd3 (potassium voltage-gated channel, Shal-related family, member 3 [Source:MGI Symbol;Acc:MGI:1928743])

HSP 1 Score: 550.436 bits (1417), Expect = 0.000e+0
Identity = 303/491 (61.71%), Postives = 387/491 (78.82%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRE-LVDD 1571
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR +L++Y+TGKLH P++EC+SAYDDEL+F+GILP+I+GDCCYE+Y+D++REN +R ++D ++E+ +  +P L + R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C     + E   CGE Y  AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  +   ++ +        KRN L +   +   T +++    G   +L+E QHHHLL CLE  TG   LVDD
Sbjct:   18 GWMPVANCPMPL-APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL-SFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELP-CGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHS--------KRNGLLNEALELTGTPEEEQ--MGKTTSLIESQHHHLLHCLEKTTGLSYLVDD 495          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Mouse
Match: Kcnd3 (potassium voltage-gated channel, Shal-related family, member 3 [Source:MGI Symbol;Acc:MGI:1928743])

HSP 1 Score: 550.436 bits (1417), Expect = 0.000e+0
Identity = 303/491 (61.71%), Postives = 387/491 (78.82%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRK--LPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRE-LVDD 1571
            GW+P+ N  +P     + + R +E + +NVSG +F+TW+ TL++Y DTLLGS EK++F++E  KEYFFDRDP++FR +L++Y+TGKLH P++EC+SAYDDEL+F+GILP+I+GDCCYE+Y+D++REN +R ++D ++E+ +  +P L + R+ +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C     + E   CGE Y  AFFCLDTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAI+PYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI +AK  +   ++ +        KRN L +   +   T +++    G   +L+E QHHHLL CLE  TG   LVDD
Sbjct:   18 GWMPVANCPMPL-APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL-SFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELP-CGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHS--------KRNGLLNEALELTGTPEEEQ--MGKTTSLIESQHHHLLHCLEKTTGLSYLVDD 495          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. UniProt/SwissProt
Match: sp|P17971|KCNAL_DROME (Potassium voltage-gated channel protein Shal OS=Drosophila melanogaster OX=7227 GN=Shal PE=1 SV=2)

HSP 1 Score: 569.696 bits (1467), Expect = 0.000e+0
Identity = 319/490 (65.10%), Postives = 392/490 (80.00%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSE-EKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE--DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVD 1568
            GWVP+  H LP P + +   +++ EK+ INVSG +FETW+NTL+KY DTLLGS+E+++FYDE  KEYFFDRDPDIFR+IL+YY+TGKLH PKHEC+++YD+EL+FFGI+PD++GDCCYEDYRD++REN +R ++D+ +E  D+ L  L  +R+K+WRAF+NP TS +ALVFYYVTGFFIAVSV+ANVVET+ C        +  CGE Y+  FFCLDTACV+IFT EYL RL+AAP R KFVRS+MS+IDVVAI+PYYIGL I+ N+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFL+FSL+MA+IIFAT+++YAEK+   T FTSIPA+FWYTIVTMTTLGYGDM P+T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI +AK  +   F+  K  A+ R      Q S  + D  Y          E + E+QHHHLL CLE  T RE V+
Sbjct:   17 GWVPIATHPLPPPPMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLGSNEREFFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARW---AAQESGIELDDNYR--------DEDIFELQHHHLLRCLEKTTDREFVE 495          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. UniProt/SwissProt
Match: sp|Q9NSA2|KCND1_HUMAN (Potassium voltage-gated channel subfamily D member 1 OS=Homo sapiens OX=9606 GN=KCND1 PE=1 SV=2)

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 310/495 (62.63%), Postives = 379/495 (76.57%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDR----KLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNAN-TNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSEND--EDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+PL    LP P       R +E + +NVSG +FETWKNTLD+Y DTLLGS EK++FYD    EYFFDRDPD+FR++L++Y+TG+LHCP+ EC+ A+D+EL+F+G++P+++GDCC E+YRD+++EN +R  ED EAE       LP   ++R++LWRAF+NP TS AALVFYYVTGFFIAVSV+ANVVETI C  +A  ++  + CGE + +AFFC+DTACVLIFT EYL RL+AAP R +F+RS+MSLIDVVAILPYYIGLL+ KN+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK   KT FTSIPA+FWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQQK R ARI LAK+     F               LQ+ +N   ED    ++  +     +  E QHHHLL CLE  T  E  D+
Sbjct:   18 GWLPLAQQPLP-PAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAF---------------LQYKQNGGLEDSGSGEEQALCVRNRSAFEQQHHHLLHCLEKTTCHEFTDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. UniProt/SwissProt
Match: sp|Q03719|KCND1_MOUSE (Potassium voltage-gated channel subfamily D member 1 OS=Mus musculus OX=10090 GN=Kcnd1 PE=1 SV=1)

HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0
Identity = 306/493 (62.07%), Postives = 378/493 (76.67%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDR----KLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNAN-TNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+PL    LP P  +    R +E + +NVSG +FETWKNTLD+Y DTLLGS EK++FYD    EYFFDRDPD+FR++L++Y+TG+LHCP+ EC+ A+D+EL+F+G++P+++GDCC E+YRD+++EN +R  ED EAE       LP   ++R++LWRAF+NP TS AALVFYYVTGFFIAVSV+ANVVETI C       ++ ++CG+ +  AFFC+DTACVLIFT EYL RL+AAP R +F+RS+MSLIDVVAILPYYIGL + KN+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK   KT FTSIPA+FWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQQK R ARI LAK+     F++ K       +   L+ S + +      +S       +  E QHHHLL CLE  T  E  D+
Sbjct:   18 GWLPLAQQPLP-PAPEVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDAESGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGEGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGTPRWPSKEQSCGDRFPTAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTSKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYK-------QNGGLEDSGSGDGQMLCVRS------RSAFEQQHHHLLHCLEKTTCHEFTDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. UniProt/SwissProt
Match: sp|Q9NZV8|KCND2_HUMAN (Potassium voltage-gated channel subfamily D member 2 OS=Homo sapiens OX=9606 GN=KCND2 PE=1 SV=2)

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 303/491 (61.71%), Postives = 382/491 (77.80%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDRE---AEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ +  +P P  QE     +  + +NVSG +F+TW++TL++Y DTLLGS E+D+FY    ++YFFDRDPDIFR+IL++Y+TGKLH P+HEC+SAYD+EL+FFG++P+I+GDCCYE+Y+D++REN +R  +D +   A +  LP + T R+++WRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C  +    +   CGE Y  AFFCLDTACV+IFT+EYL RL AAP R +FVRS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI  AK+ +   ++++K         N LQ SE+++ +     S+         E QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTM-TARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNG---LLSNQLQSSEDEQAFVSKSGSS--------FETQHHHLLHCLEKTTNHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. UniProt/SwissProt
Match: sp|Q8HYZ1|KCND2_MUSPF (Potassium voltage-gated channel subfamily D member 2 OS=Mustela putorius furo OX=9669 GN=KCND2 PE=2 SV=1)

HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0
Identity = 302/491 (61.51%), Postives = 381/491 (77.60%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ +  +P P  QE     +  + +NVSG +F+TW++TL++Y DTLLGS E+D+FY    ++YFFDRDPDIFR+IL++Y+TGKLH P+HEC+SAYD+EL+FFG++P+I+GDCCYE+Y+D++REN +R  +D + +   +  LP + T R+++WRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C  +    +   CGE Y  AFFCLDTACV+IFT+EYL RL AAP R +FVRS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+KAR ARI  AK  +   ++++K         N LQ SE+++ +     S+         E QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDNTGESALPTM-TARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKTGSANAYMQSKRNG---LLSNQLQSSEDEQAFVSKSGSS--------FETQHHHLLHCLEKTTNHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. TrEMBL
Match: A0A3S1C1P2 (BTB domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_011743 PE=3 SV=1)

HSP 1 Score: 607.446 bits (1565), Expect = 0.000e+0
Identity = 327/488 (67.01%), Postives = 394/488 (80.74%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGV-KETLLEIQHHHLLSCLEMVTGRELVD 1568
            GWVP++ + LP PT++    R +EK++INVSG +FETW+ TL+KY D+LLGS+E+++FYDE  KEYFFDRDPD+FR+IL+YY+T +LH PKHEC+SAYD+EL+FFGILPDI+GDCCYEDYRD++REN +R I+D ++E+       ++REK+WRAF+NP     ALVFYYVTGFFIAVSV+ANVVET+ C       E   CGE YE AFFCLDTACV+IFT EYL RLYAAP R KF+RS+MS+IDVVAI+PYYIGL+IS N+D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT++YYAEK+   T FTSIPA+FWYTIVTMTTLGYGDMTP T+ GK++GGICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR+ARI +AKN +   FI  K +A+E      L H    E        +  GV K  + E+QHHHLL+CLE  T RE V+
Sbjct:   17 GWVPISQNPLPTPTVRPESRRGDEKLRINVSGRRFETWRTTLEKYPDSLLGSNEREFFYDEETKEYFFDRDPDLFRHILNYYRTSRLHYPKHECISAYDEELAFFGILPDIIGDCCYEDYRDRKRENSERLIDDEKSENGDFDPAISLREKMWRAFENPHIGTIALVFYYVTGFFIAVSVMANVVETVKCGKMPGVREEPACGERYEPAFFCLDTACVMIFTAEYLLRLYAAPDRCKFMRSVMSIIDVVAIIPYYIGLVISDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATIMYYAEKNVAGTNFTSIPAAFWYTIVTMTTLGYGDMTPDTIPGKIVGGICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKAREARINMAKNASSAGFISAKKRAEE----AMLAHQAGME------LEDDEGVRKNDIFEMQHHHLLTCLEKTTDREFVE 494          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. TrEMBL
Match: A0A1I8JFA1 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 606.675 bits (1563), Expect = 0.000e+0
Identity = 325/495 (65.66%), Postives = 399/495 (80.61%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSEND--------EDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVD 1568
            GWVP+    +P P +++ DH+S+EK+ I+VSG KF TW+NTL+K+ DTLLGSDEK+YFYDE  K+YFFDRDPD+FR+IL+YY+TG+LH PK+EC+ AYD+EL+FFGI+PDIMGDCCYEDYRD++REN++R  +D++++        T REKLWRAF+NPQ+S  ALV YYVTGFFIAVSVLANV ETI C     TN S  CG+ +  AFFCLDTACVLIFT+EYLARLYAAP+R+K +R++MS+ID+VAILPYYIGL +  N D+SGAFV LRVFRVFRI KFSRHSMGLRILGYTLKSCASELGFLLFS++MAVIIFAT++YYAEK+  KT F SIPA+FWYTIVTMTTLGYGD+ P T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI +AKN +   FI +K +A+ER++   LQ +E               D   +    +E + E+QHHHLL+CLE  T RE V+
Sbjct:   65 GWVPVAQGPMPPPPLRDEDHKSDEKLVISVSGRKFVTWRNTLEKFPDTLLGSDEKEYFYDEDSKQYFFDRDPDLFRHILAYYRTGRLHYPKNECIMAYDEELAFFGIMPDIMGDCCYEDYRDRKRENNERLFDDKDSDAENAMPHSTPREKLWRAFENPQSSTVALVVYYVTGFFIAVSVLANVFETIPCGVEPGTNLSPACGDRFSVAFFCLDTACVLIFTVEYLARLYAAPQRLKHLRAVMSVIDIVAILPYYIGLFMPDNKDLSGAFVTLRVFRVFRIFKFSRHSMGLRILGYTLKSCASELGFLLFSMTMAVIIFATVMYYAEKNQPKTGFVSIPAAFWYTIVTMTTLGYGDIVPSTIIGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKARLARIRMAKNASGAAFISSKKRAEERQR---LQETEIGGAECGSIRGSGAGDDSGSSADRREDVFELQHHHLLTCLERTTEREFVE 556          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. TrEMBL
Match: A0A267E2A4 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020078g10 PE=3 SV=1)

HSP 1 Score: 606.29 bits (1562), Expect = 0.000e+0
Identity = 325/495 (65.66%), Postives = 399/495 (80.61%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSEND--------EDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVD 1568
            GWVP+    +P P +++ DH+S+EK+ I+VSG KF TW+NTL+K+ DTLLGSDEK+YFYDE  K+YFFDRDPD+FR+IL+YY+TG+LH PK+EC+ AYD+EL+FFGI+PDIMGDCCYEDYRD++REN++R  +D++++        T REKLWRAF+NPQ+S  ALV YYVTGFFIAVSVLANV ETI C     TN S  CG+ +  AFFCLDTACVLIFT+EYLARLYAAP+R+K +R++MS+ID+VAILPYYIGL +  N D+SGAFV LRVFRVFRI KFSRHSMGLRILGYTLKSCASELGFLLFS++MAVIIFAT++YYAEK+  KT F SIPA+FWYTIVTMTTLGYGD+ P T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI +AKN +   FI +K +A+ER++   LQ +E               D   +    +E + E+QHHHLL+CLE  T RE V+
Sbjct:   17 GWVPVAQGPMPPPPLRDEDHKSDEKLIISVSGRKFVTWRNTLEKFPDTLLGSDEKEYFYDEDSKQYFFDRDPDLFRHILAYYRTGRLHYPKNECIMAYDEELAFFGIMPDIMGDCCYEDYRDRKRENNERLFDDKDSDAENAMPHSTPREKLWRAFENPQSSTVALVVYYVTGFFIAVSVLANVFETIPCGVEPGTNLSPACGDRFSVAFFCLDTACVLIFTVEYLARLYAAPQRLKHLRAVMSVIDIVAILPYYIGLFMPDNKDLSGAFVTLRVFRVFRIFKFSRHSMGLRILGYTLKSCASELGFLLFSMTMAVIIFATVMYYAEKNQPKTGFVSIPAAFWYTIVTMTTLGYGDIVPSTIIGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKARLARIRMAKNASGAAFISSKKRAEERQR---LQETEIGGAECGSIRGSGAGDDSGSSADRREDVFELQHHHLLTCLERTTEREFVE 508          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. TrEMBL
Match: A0A1I8JED2 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 605.905 bits (1561), Expect = 0.000e+0
Identity = 325/495 (65.66%), Postives = 399/495 (80.61%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSEND--------EDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVD 1568
            GWVP+    +P P +++ DH+S+EK+ I+VSG KF TW+NTL+K+ DTLLGSDEK+YFYDE  K+YFFDRDPD+FR+IL+YY+TG+LH PK+EC+ AYD+EL+FFGI+PDIMGDCCYEDYRD++REN++R  +D++++        T REKLWRAF+NPQ+S  ALV YYVTGFFIAVSVLANV ETI C     TN S  CG+ +  AFFCLDTACVLIFT+EYLARLYAAP+R+K +R++MS+ID+VAILPYYIGL +  N D+SGAFV LRVFRVFRI KFSRHSMGLRILGYTLKSCASELGFLLFS++MAVIIFAT++YYAEK+  KT F SIPA+FWYTIVTMTTLGYGD+ P T+ GK++GG+CSLSG+LVIALPVPVIVSNFSRIYHQNQRADKRKAQ+KAR ARI +AKN +   FI +K +A+ER++   LQ +E               D   +    +E + E+QHHHLL+CLE  T RE V+
Sbjct:   48 GWVPVAQGPMPPPPLRDEDHKSDEKLIISVSGRKFVTWRNTLEKFPDTLLGSDEKEYFYDEDSKQYFFDRDPDLFRHILAYYRTGRLHYPKNECIMAYDEELAFFGIMPDIMGDCCYEDYRDRKRENNERLFDDKDSDAENAMPHSTPREKLWRAFENPQSSTVALVVYYVTGFFIAVSVLANVFETIPCGVEPGTNLSPACGDRFSVAFFCLDTACVLIFTVEYLARLYAAPQRLKHLRAVMSVIDIVAILPYYIGLFMPDNKDLSGAFVTLRVFRVFRIFKFSRHSMGLRILGYTLKSCASELGFLLFSMTMAVIIFATVMYYAEKNQPKTGFVSIPAAFWYTIVTMTTLGYGDIVPSTIIGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKARLARIRMAKNASGAAFISSKKRAEERQR---LQETEIGGAECGSIRGSGAGDDSGSSADRREDVFELQHHHLLTCLERTTEREFVE 539          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. TrEMBL
Match: A0A1I8IL69 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 318/481 (66.11%), Postives = 394/481 (81.91%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVT 1550
            GWVP+    +P P +++ DH+S+EK+ I+VSG KF TW+NTL+K+ DTLLGSDEK+YFYDE  K+YFFDRDPD+FR+IL+YY+TG+LH PK+EC+ AYD+EL+FFGI+PDIMGDCCYEDYRD++REN++R  +D++++        T REKLWRAF+NPQ+S  ALV YYVTGFFIAVSVLANV ETI C     TN    CG+ + KAFFCLDTACVLIFT+EYLARLYAAP+R+K +R++MS+ID+VAILPYYIGL +  N D+SGAFV LRVFRVFRI KFSRHSMGLRILGYTLKSC SELGFLLFS++MAVIIFAT++YYAEK+  KT F SIPA+FWYT+VTMTTLGYGDM P T+ GK++GG+CSLSG+LVIALPVPVIVS+FSRIYHQNQRADKRKAQ+KAR ARI +AK  +   FI +K +A+ERR+   ++ ++         ++   G +E + E+QHHHLLSCLE  T
Sbjct:  473 GWVPVAQGPMPPPPLRDEDHKSDEKLVISVSGRKFVTWRNTLEKFPDTLLGSDEKEYFYDEDSKQYFFDRDPDLFRHILAYYRTGRLHYPKNECIMAYDEELAFFGIMPDIMGDCCYEDYRDRKRENNERLFDDKDSDAENAMPHSTPREKLWRAFENPQSSTTALVIYYVTGFFIAVSVLANVFETIPCGVEPGTNLVLACGDRFTKAFFCLDTACVLIFTVEYLARLYAAPERLKQMRAVMSVIDIVAILPYYIGLFMPDNKDLSGAFVTLRVFRVFRIFKFSRHSMGLRILGYTLKSCVSELGFLLFSMTMAVIIFATVMYYAEKNQPKTGFVSIPAAFWYTVVTMTTLGYGDMVPTTIIGKIVGGVCSLSGVLVIALPVPVIVSSFSRIYHQNQRADKRKAQKKARLARIKMAKTASGAAFISSKKRAEERRRELQIEDADGCGSSGGAARAAGEGREEDVFELQHHHLLSCLERTT 953          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Cavefish
Match: ENSAMXT00000026139.2 (potassium voltage-gated channel subfamily D member 3 [Source:NCBI gene;Acc:103023694])

HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0
Identity = 303/491 (61.71%), Postives = 384/491 (78.21%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREA-EDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXX--XXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ N  +P P  +E   + +E + +NVSG +F+TW+ TLD+Y DTLLGS EK++FY+E  KEYFFDRDPD FR +L++Y+TGKLH P++EC+SAYD+EL+FFGI+P+I+GDCCYE+Y+D++REN +R ++D+E  +D +LP +   RE +WRAF+NP TS  ALVFYYVTGFFIAVSV+ NVVET+ C    N  +   CGE Y  AFFC+DTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRA   + +  QKAR ARI +AK  +   ++++        KRN L +   D   + +++ ++N    +LLE QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVANCPMP-PAPREHSKKQDELIILNVSGRRFQTWRTTLDRYPDTLLGSTEKEFFYNEETKEYFFDRDPDAFRSVLNFYRTGKLHYPRYECISAYDEELAFFGIIPEIIGDCCYEEYKDRKRENAERLMDDQEENKDSRLPNMN-FRETMWRAFENPHTSTMALVFYYVTGFFIAVSVITNVVETVPCGSTPNQKDVP-CGERYTVAFFCMDTACVMIFTVEYLLRLFAAPSRYRFMRSVMSIIDVVAILPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKVQKARLARIRIAKKGSSNAYLQS--------KRNGLLNELLDLTSSEEEEQHMNKTS-SLLESQHHHLLHCLEKTTAHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Cavefish
Match: kcnd3 (potassium voltage-gated channel subfamily D member 3-like [Source:NCBI gene;Acc:103032692])

HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0
Identity = 298/492 (60.57%), Postives = 381/492 (77.44%), Query Frame = 3
Query:  108 GWVPLTNHSLP-KPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDRE-AEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXX--XXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ N  +P  PT  E +   +E + +NVSG +F+TW+NTLD+Y DTLLGS EK++F++E  +EYFFDRDPD+FR IL++Y+TGKLH P++EC+SAYD+EL+FFGI+P+I+ DCCYE+Y+D++REN +R ++D E  +D KLP + T RE +WRAF+NP TS  ALVFYYVTGFFIA+SV+ NVVET+ C    N  +   CGE Y  AFFC+DTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRA   + +  QKAR  R+ ++K  +   F+ +        KRN + +   +   +   + ++N    +++E QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVANLPMPVAPT--EKNKCQDELIILNVSGRRFQTWRNTLDRYPDTLLGSSEKEFFFNEETREYFFDRDPDVFRSILNFYRTGKLHYPRYECISAYDEELAFFGIIPEIISDCCYEEYKDRKRENAERLMDDNEDGKDSKLPNM-TFRETMWRAFENPHTSTMALVFYYVTGFFIAISVITNVVETVPCGSMPNQRDIP-CGERYTVAFFCMDTACVMIFTVEYLMRLFAAPSRYRFMRSVMSIIDVVAILPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSASSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKMQKARLTRMRISKTGSSNAFLHS--------KRNGMPNQALELPSSTGDERHLNKTT-SIIESQHHHLLHCLEKTTNHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Cavefish
Match: kcnd1 (potassium voltage-gated channel subfamily D member 1 [Source:NCBI gene;Acc:103038349])

HSP 1 Score: 548.125 bits (1411), Expect = 0.000e+0
Identity = 292/432 (67.59%), Postives = 354/432 (81.94%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNK 1394
            GW+PL   ++PKP + +   RS+E + +NVSG +F+TWKNTLD+Y DTLLGS EK++FY+E  +EYFFDRDP++FR+IL++Y+TGKLH P+ EC+ A+D+EL+F+GI+PDI+GDCC E+YRD+++EN +R  ED EAE   D  LP   T RE+LWRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C     + +   CGE Y  AFFC+DTACVLIFT EYL RL+AAP R KF+RS+MS+IDVVAI+PYYIGL++ +N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    T FTSIPASFWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADK +AQQK R ARI +AK      F++ K
Sbjct:   18 GWLPLAKKTMPKPPV-DKKSRSDEILIVNVSGLRFQTWKNTLDRYPDTLLGSSEKEFFYNEDTQEYFFDRDPEMFRHILNFYRTGKLHYPRQECIQAFDEELAFYGIVPDIIGDCCMEEYRDRKKENQERLAEDTEAEMATDVPLPPNSTPRERLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCRPPKGSVKDLPCGEKYSVAFFCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSVIDVVAIMPYYIGLVMPENEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTKGTNFTSIPASFWYTIVTMTTLGYGDMVPNTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKMRAQQKVRLARIRMAKKGTTNAFLQYK 448          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Cavefish
Match: kcnd1 (potassium voltage-gated channel subfamily D member 1 [Source:NCBI gene;Acc:103038349])

HSP 1 Score: 548.125 bits (1411), Expect = 0.000e+0
Identity = 292/432 (67.59%), Postives = 354/432 (81.94%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNK 1394
            GW+PL   ++PKP + +   RS+E + +NVSG +F+TWKNTLD+Y DTLLGS EK++FY+E  +EYFFDRDP++FR+IL++Y+TGKLH P+ EC+ A+D+EL+F+GI+PDI+GDCC E+YRD+++EN +R  ED EAE   D  LP   T RE+LWRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C     + +   CGE Y  AFFC+DTACVLIFT EYL RL+AAP R KF+RS+MS+IDVVAI+PYYIGL++ +N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    T FTSIPASFWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADK +AQQK R ARI +AK      F++ K
Sbjct:   18 GWLPLAKKTMPKPPV-DKKSRSDEILIVNVSGLRFQTWKNTLDRYPDTLLGSSEKEFFYNEDTQEYFFDRDPEMFRHILNFYRTGKLHYPRQECIQAFDEELAFYGIVPDIIGDCCMEEYRDRKKENQERLAEDTEAEMATDVPLPPNSTPRERLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCRPPKGSVKDLPCGEKYSVAFFCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSVIDVVAIMPYYIGLVMPENEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTKGTNFTSIPASFWYTIVTMTTLGYGDMVPNTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKMRAQQKVRLARIRMAKKGTTNAFLQYK 448          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Cavefish
Match: kcnd1 (potassium voltage-gated channel subfamily D member 1 [Source:NCBI gene;Acc:103038349])

HSP 1 Score: 544.273 bits (1401), Expect = 0.000e+0
Identity = 273/398 (68.59%), Postives = 331/398 (83.17%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYH 1292
            GW+PL   ++PKP + +   RS+E + +NVSG +F+TWKNTLD+Y DTLLGS EK++FY+E  +EYFFDRDP++FR+IL++Y+TGKLH P+ EC+ A+D+EL+F+GI+PDI+GDCC E+YRD+++EN +R  ED EAE   D  LP   T RE+LWRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C     + +   CGE Y  AFFC+DTACVLIFT EYL RL+AAP R KF+RS+MS+IDVVAI+PYYIGL++ +N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    T FTSIPASFWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYH
Sbjct:   18 GWLPLAKKTMPKPPVDK-KSRSDEILIVNVSGLRFQTWKNTLDRYPDTLLGSSEKEFFYNEDTQEYFFDRDPEMFRHILNFYRTGKLHYPRQECIQAFDEELAFYGIVPDIIGDCCMEEYRDRKKENQERLAEDTEAEMATDVPLPPNSTPRERLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCRPPKGSVKDLPCGEKYSVAFFCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSVIDVVAIMPYYIGLVMPENEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTKGTNFTSIPASFWYTIVTMTTLGYGDMVPNTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYH 414          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004235.1 (pep scaffold:Pmarinus_7.0:GL476413:398954:411573:-1 gene:ENSPMAG00000003870.1 transcript:ENSPMAT00000004235.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 218.394 bits (555), Expect = 8.416e-64
Identity = 119/361 (32.96%), Postives = 195/361 (54.02%), Query Frame = 3
Query:  180 KVKINVSGFKFETWKNTLDKYSDTLLGS----------DEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDR------TIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFV-------ILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTV 1193
            +V++NV G   E    TL++   T LG            E    Y   + EYFFDR P  F  +L++Y+TG+LH  +  C  ++  EL ++G+    +  CC   Y  K+ +  +       +  +RE ++ +       R KLW   +NP +S+AA     V+  FI +S +A  + T+  D       S             ++  C+  FT+EYL R  +AP + KF +  +++ID++AILPYYI + +++++     F        I R+ R+ RI+K +RHS GL+ LG+TL+   +ELG L+  L+M ++IF++++++AEK +  T F SIPASFW+  +TMTT+GYGD+ P T+
Sbjct:    1 RVRLNVGGLVHEVLWRTLERLPRTRLGRLHATNTHGALSELCDDYSIADNEYFFDRHPGAFASVLNFYRTGRLHMSEEMCALSFGQELDYWGVDEIYLETCCQARYHQKKEQMSEELRREAESAREREGDEFEGTCCADKRRKLWELLENPNSSLAAKGMAIVSILFIVLSTIALSLNTLP-DLQHKDEFSHIIDN---PKLAQVEAVCIAWFTMEYLLRFMSAPNKWKFFKGALNVIDLMAILPYYITIFLTESSRGVSQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEPDTKFHSIPASFWWATITMTTVGYGDIYPMTL 357          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221])

HSP 1 Score: 216.853 bits (551), Expect = 1.240e-62
Identity = 156/405 (38.52%), Postives = 235/405 (58.02%), Query Frame = 3
Query:  147 TIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEK-DYFYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETI-------------SCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLI-------SKNNDMSGAFV-ILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYH 1292
            T +   H   E++ INVSG +FET   +LD++ DTLLG+  K   ++D +  EYFFDR+   F  IL YYQ+G +L  P +  +  + +E+ F+ +  + M          K +E+     E    E++ LP     + ++W  F+ P++S  A     V+   I +S++   +ET+             + D N  T      G ++   FF ++T C++ F+ E L R +A P +  F +SIM++ID+VAILPY+I L         S    MS A + ++R+ RVFRI K SRHS GL+ILG TLK+   ELG L+F L + VI+F++ +Y+AE     + F SIP +FW+ +VTMTT+GYGDM P TV GK++G +C+++G+L IALPVPVIVSNF+  YH
Sbjct:   18 TAEPLTHEYCERIVINVSGLRFETQLKSLDQFPDTLLGNPSKRSRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVSIDVFSEEIKFYELGNEAMA---------KFQEDEGFIKE----EEKPLPS-DEFQRQVWLLFEYPESSNPARGIAIVSVLVILISIIIFCLETLPEFRDEKEQKFLPAKDING-TQVKIMHGSSFTDPFFIVETICIIWFSFELLVRFFACPSKPGFFKSIMNIIDIVAILPYFITLGTEMAKHQGSGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADHQNSEFRSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 407          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Sea Lamprey
Match: kcnc1a (potassium voltage-gated channel, Shaw-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-061220-10])

HSP 1 Score: 217.624 bits (553), Expect = 1.381e-61
Identity = 141/393 (35.88%), Postives = 211/393 (53.69%), Query Frame = 3
Query:  177 EKVKINVSGFKFETWKNTLDKYSDTLLGS-DEKDYF----YDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQR-------------ENHDRTIEDREAEDR-----------KLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNA--NTNESKTCGE-TYEKAFFCLDT---------ACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYY--IGL--LISK-NNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEK---------SDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKT 1190
            E+V INV G + ET++ TL     T L    E D F    YD    E+FFDR P +F +IL+YY+TGKLHCP   C   +++EL F+GI    +  CC+ +YR  +                +D   ED E   R           KL  L+  + ++W  F++P +S AA +    +  FI +S+    +ET    FN   N  E+ T    T +K +  ++T          CV  F+ E+L R+   P +  F+++ +++ID VAILP+Y  +GL  L SK   D+ G   ++R  R+ RI K +RH +GLR+LG+TL++  +E   L+  L++ V+IFATMI+YAE+         +   T+F +IP  FW+ +VTMTTLGYGDM P+T
Sbjct:   36 ERVVINVGGTRHETYRGTLRTLPGTRLSWLTEPDAFANFDYDAKGNEFFFDRHPTVFAHILNYYRTGKLHCPSEVCGPLFEEELIFWGIDETDVEPCCWMNYRQHRDAEEALVSFENPDINGNDEVNEDGEVSKRFGLDERSPDGGKLGFLRRWQPRMWALFEDPYSSRAARIVALASLLFILISITTFCLETHEA-FNTVLNKTENYTINNVTTQKVYVDVETDPVLMYVEGVCVAWFSFEFLVRIICCPDKKVFIKNYLNVIDFVAILPFYLEVGLSSLTSKPARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIFYAERFGANPNDPTASDHTSFKNIPIGFWWAVVTMTTLGYGDMYPQT 427          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221])

HSP 1 Score: 209.534 bits (532), Expect = 8.742e-60
Identity = 137/384 (35.68%), Postives = 212/384 (55.21%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDY-FYDEVEKEYFFDRDPDIFRYILSYYQTG-KLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESK----TCGETY------EKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLI-------SKNNDMSGAFVILRVFR---VFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTV 1193
            G  P   + L +P      H   E+V INVSG +FET   TL ++ DTLLG  +K   ++D +  EYFFDR+   F  IL YYQ+G +L  P       + +E+ F+ +  + M        R ++ E + +  E    E+         + ++W  F+ P++S  A     V+   I +S++   +ET+  +F  + +  K    T G  Y         FF ++T C++ F+ E + R  A P +++F +++M++ID+VAI+PY+I L         S N   + +  ILRV R   VFRI K SRHS GL+ILG+TL +   ELG L+F L + VI+F++ +++AE    KT F SIP +FW+++VTMTT+GYGDM+PKTV
Sbjct:   19 GGYPQERYELARPG----GHDFCERVVINVSGLRFETQLRTLAQFPDTLLGDPQKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVSVPYDIFTEEVRFYDLGEETM-------LRYREDEGYVKEPEKPLPENE-------FQRQVWLLFEYPESSSPARAIAIVSVLVILISIIIFCLETLP-EFRDDADLYKVSYYTNGTHYFYHNVFADPFFIMETICIIWFSFELMVRFCACPSKVEFGKNLMNIIDIVAIVPYFITLGTEMAEQTGSANGQQTMSLAILRVIRLVRVFRIFKLSRHSKGLQILGHTLHASMRELGLLIFFLFIGVILFSSAVFFAEVDSKKTEFQSIPDAFWWSLVTMTTVGYGDMSPKTV 383          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1])

HSP 1 Score: 202.986 bits (515), Expect = 1.129e-58
Identity = 126/351 (35.90%), Postives = 189/351 (53.85%), Query Frame = 3
Query:  177 EKVKINVSGFKFETWKNTLDKYSDTLLG-SDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVS-AYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISC-----DFNANTNESKTCGETYE-KAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLI----SKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTV 1193
            ++V INVSG +FET   TLD++ D+LLG  D++  ++D ++ EYFFDR    F  IL YYQ+G   C   +  S  + +E+ F+ +          E+   K  EN   T E+           K  ++ +WR F++   S+AA +   ++     +S+    +ET+         +AN  E       Y    FF L+TACV+ F  E   R YA P +  F++  M+ ID++AI+PY+I +++     ++        I+R+ RV RI K SRH   L+ILG TLK+   EL  L F L +AV+IF+  IYY E  D +  F+SIP +FW+ +VTMT +GYGDM P TV
Sbjct:    1 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYEL---------GEEAVAKYGENTLDTPEEENVHG------KDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQDQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVEADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTV 336          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Nematostella
Match: EDO31803 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWW6])

HSP 1 Score: 479.559 bits (1233), Expect = 1.092e-162
Identity = 268/490 (54.69%), Postives = 347/490 (70.82%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIE----DREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIY-HXXXXXXXXXXXXXXXXXXIALAKNYNCTNFI----KNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVT 1550
            GWVPL    +          +++E+V INVSG +FETW+NTL ++ +TLLGSDEKDYFYD   KEYFFDRDPD+FR++L+YY+ GKLH P+ ECVS+++DEL FFGI  D++ DCC+ED+R++++E  +R  E    D  +++       +IREKLW AF NPQ+S  A VFYY+TG FIA+SV++ VVET+ C          +CGE ++  FF L+ ACV++FT+EY+ARLY+AP R+KF R ++S+IDVVAILP+Y+GL++  NN +SGAFV LRVFR+FRI KFSRHS GLRILGYTLKSCASELGFLLFSLSMAVIIFAT++YY EK ++ T F SIPASFWYTIVTMTTLGYGDM P TV GK++G +CSLSG+LVIALPVPVIVSNFSRIY    +   ++  +   RKAR++++K    T  +    K  +      +   +   +N+  Y               LE QHHHLL CLE  T
Sbjct:   18 GWVPLATSPM---PPPPESSKTDERVTINVSGRRFETWRNTLARFPETLLGSDEKDYFYDAETKEYFFDRDPDLFRHLLNYYRNGKLHYPRGECVSSFEDELEFFGISEDVVHDCCWEDFRERKKECMERIFEPDKLDDASQNGDEVTDHSIREKLWTAFQNPQSSKVASVFYYITGLFIAISVISTVVETLPC------KGKTSCGEVHKTVFFSLEAACVVVFTVEYVARLYSAPDRVKFARDLLSIIDVVAILPFYVGLIVP-NNSISGAFVTLRVFRIFRIFKFSRHSRGLRILGYTLKSCASELGFLLFSLSMAVIIFATVMYYVEKGEVDTKFISIPASFWYTIVTMTTLGYGDMVPTTVPGKIVGSLCSLSGVLVIALPVPVIVSNFSRIYLQNQRADKRKAHKVSTRKARVSISKTMAGTALVSPPDKKNVPLGAGLELTQIPSKDNESSY---------------LEEQHHHLLHCLEKAT 482          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Nematostella
Match: EDO31311 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYB8])

HSP 1 Score: 338.191 bits (866), Expect = 4.974e-109
Identity = 173/369 (46.88%), Postives = 238/369 (64.50%), Query Frame = 3
Query:  108 GWVPLTNHS---LPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQREN--HDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLL---ISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKT 1190
            G  PL       L +P+ ++ D R    V +N+SG KFETW+ TL+KY +TLLG   KD FYD+ ++EYFFDRDP  FR++L+YY+ GKLH    EC   Y +EL FF I PD +  CC+E++ +    N    R   +   +     V K++R+++W  F+NP  S    + Y VTG  I VS+L  + ETI C      + ++TCGE +  AFF +D  CV IFTLEYL RL +AP+R  FV++  S+IDV +++P+Y+ +L   IS  +  +    ILRVFRVFR++K SRHS  L+ LG ++K+ +SELGF+LFS S+ V+IFAT+IYY EK +L T+F SIP   WY IVTMTT GYGDMTP+T
Sbjct:   22 GMAPLATSRSSLLVRPSTRDNDRR----VVLNISGRKFETWETTLEKYPETLLGGKGKDSFYDKEKQEYFFDRDPVFFRHVLNYYRKGKLHFSLEECGKFYKEELKFFKISPDNVDLCCFEEFEESVSLNFRKPRPPGESRCDCSVQKVRKSLRQRVWDLFENPYNSSLGKITYAVTGIAIIVSILTTITETIPC------STTRTCGELHASAFFIVDGVCVGIFTLEYLVRLLSAPERWPFVKNFQSIIDVASVMPFYLDILFEQISGGSSGAEGLTILRVFRVFRVVKMSRHSKRLQSLGASIKNSSSELGFILFSFSLGVVIFATVIYYCEKDELNTSFLSIPDGMWYAIVTMTTTGYGDMTPET 380          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Nematostella
Match: EDO47580 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLC8])

HSP 1 Score: 317.39 bits (812), Expect = 2.308e-101
Identity = 161/348 (46.26%), Postives = 230/348 (66.09%), Query Frame = 3
Query:  177 EKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRT--IEDR-EAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETI--SCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISK----NNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKT-TFTSIPASFWYTIVTMTTLGYGDMTPKT 1190
            +++ + V G  FETW+  L K+  TLLGS EK+ +Y+   K Y F+RDP +FR+IL+YY+ G+LH     C   + +ELSFFGI  + + +CC++DYR  ++ N D+   +ED  E  +  +PV  T++E++W  FDNP+ S   L++YYV+G  IA+S+   V ETI   CD      ES  CG  Y  AFF L++ CV +FT EYL+RL  APKR  FV+  MS+IDVV+ILPYY G+++      + D  G+ V+LRV RVFR++KF+RHS  LR L + ++  ASELGF++FSLS+ V++ ++M+YY EK       F SIPA+ WY++VTMTT GYGD+ P T
Sbjct:    1 KRILLKVGGRVFETWEENLRKHPSTLLGSKEKELYYNPETKMYTFERDPLMFRHILNYYRAGRLHYSCDYCADEFREELSFFGISINAVDNCCWDDYRQTRKINIDKVFKLEDPLENAENGIPVKITLKERVWLIFDNPEKSFFGLLWYYVSGLMIALSIACTVAETIPPPCD------ESVICGAQYTLAFFVLESICVGVFTFEYLSRLLTAPKRWDFVKGYMSIIDVVSILPYYAGIIMENVFQTSVDSLGSLVLLRVLRVFRVLKFTRHSSRLRSLLFAIQRSASELGFIVFSLSLGVVLISSMLYYVEKDGTGGDMFNSIPATMWYSVVTMTTTGYGDLVPHT 342          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Nematostella
Match: EDO31807 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWW3])

HSP 1 Score: 312.383 bits (799), Expect = 1.075e-98
Identity = 161/362 (44.48%), Postives = 239/362 (66.02%), Query Frame = 3
Query:  141 KPTIQETDHRSEEKVK-------INVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREA----EDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTV 1193
            K  +QE + +++EK +       INVSG +F        ++ DTLLGS  K +FYD  +KEYFFDRDP++F+YI+++Y+TGKLH P+ EC   ++ E ++FGIL DIM DCC+E Y +++ +  D    ++ A    +   L      R K+W+ F+ P  ++  L+ +Y++  FIAVSV+ +VVET+ C          TCG+ YE  FF L+  CV +F+ EY  RLY+AP+R  F++  +S+ID+VAILP+Y GL++ + +  SG F +LRVFR+FRI+K SRHS  +R  G +LK   SEL F+   L+  +I+F+++IYY+E  D  + FTSIPA+FWYTIVTMTTLGYGD+ P+++
Sbjct:    5 KTALQERE-KAKEKARNRNNFTTINVSGRRFLVDIEIFSRFPDTLLGSTMKQHFYDPSKKEYFFDRDPEVFKYIITFYKTGKLHYPEEECACCFETECAYFGILADIMSDCCHEPYGEQKEDFDDYLKRNKPALGLTDPDSLKGAARFRCKMWQLFEEPSGNIFGLMLHYISAVFIAVSVVTSVVETVPCGIT-------TCGKKYEYLFFVLEAICVCLFSTEYACRLYSAPERWLFMKKFLSIIDLVAILPFYAGLIVPEAS--SGPFTVLRVFRIFRIVKMSRHSTKVRAAGSSLKDSFSELSFVFVVLAALIILFSSVIYYSESVDPNSNFTSIPATFWYTIVTMTTLGYGDLVPESL 356          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Nematostella
Match: EDO46156 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQS3])

HSP 1 Score: 285.419 bits (729), Expect = 8.690e-89
Identity = 149/352 (42.33%), Postives = 221/352 (62.78%), Query Frame = 3
Query:  165 HRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYED---YRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGL------LISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTV 1193
             +++++V +NVSG +F TW++TL KY +TLLGSD  + ++D+ ++EYF DRDP IFRYIL+YY+ GKLH    +C  ++  EL FFGI  D + DCC+ED   Y D+ RE +    E    +     + KT R  +W   +N  T +  +V   +    I VSV A++VET+ C         KTC ET+   FF LD  C++ FTLEY+ RL+AA    +F+ + ++++DV+A+ P+YI L      L  +  + + + VILR+ R+FRI K SRHS  +R +G+ LKS  S+LGFL+F+  +A ++FA+++Y+ E+      FTSIP S WYTI+TM T+GYGD  P TV
Sbjct:   10 RKNDKRVTLNVSGRRFCTWESTLKKYPNTLLGSDALNLYFDKEKREYFLDRDPHIFRYILNYYKVGKLHLSYEDCFDSFHQELLFFGISLDQVNDCCWEDCSNYVDRIRECN---CEAPRTKANNGKIYKTKR-VIWNILENTNTRLGKIV-QTLIAILIYVSVAASIVETLQCSL------GKTCEETHPTIFFALDAFCMITFTLEYILRLFAAENMREFLTNKLNILDVLAVAPFYILLCVREIELSQQMLENANSLVILRILRMFRIFKLSRHSRKMRKMGHALKSAFSDLGFLIFAFLLANVLFASVLYFIERDTSPQQFTSIPDSMWYTIITMMTVGYGDAVPVTV 350          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Medaka
Match: kcnd3 (potassium voltage-gated channel subfamily D member 3 [Source:NCBI gene;Acc:101159502])

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 308/494 (62.35%), Postives = 386/494 (78.14%), Query Frame = 3
Query:  108 GWVPLTNHSLP-KPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDRE-AEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXX--XXXXXXXXXXXXXIALAKNYNCTNFIKNKIQA--DERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ N  +P  PT  E + + +E + +NVSG +F+TWKNTLD+Y DTLLGS EK++FY+E  KEYFFDRDPD+FR +L++Y+TGKLH P++EC+ +YD+EL+FFGI+P+I+GDCCYE+Y+D++REN +R ++D+E  +D KLP + T RE +WRAF+NPQTS  ALVFYYVTGFFIAVSV+ NVVET+ C    N  E   CGE Y  AFFC+DTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRA   + +  QKAR ARI L K  + + F+ +K     +E  +   L +  +  + +  K+    G   +LLE QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVANLPMPVAPT--EKNKKQDELIVLNVSGRRFQTWKNTLDRYPDTLLGSSEKEFFYNEETKEYFFDRDPDVFRSVLNFYRTGKLHYPRYECILSYDEELAFFGIVPEIIGDCCYEEYKDRKRENAERLMDDQEDNKDSKLPNM-TFRETMWRAFENPQTSTMALVFYYVTGFFIAVSVMTNVVETVPCGSVPNQKEVP-CGERYTVAFFCMDTACVMIFTVEYLMRLFAAPNRYRFMRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKVQKARLARIRLTKTESSSAFLHSKRNGLFNEALELTQLPYKMSLSEQSSTKEEQHLGKSSSLLESQHHHLLHCLEKTTNHEFVDE 507          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Medaka
Match: kcnd3 (potassium voltage-gated channel subfamily D member 3 [Source:NCBI gene;Acc:101159502])

HSP 1 Score: 563.918 bits (1452), Expect = 0.000e+0
Identity = 311/492 (63.21%), Postives = 385/492 (78.25%), Query Frame = 3
Query:  108 GWVPLTNHSLP-KPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDRE-AEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXX--XXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+ N  +P  PT  E + + +E + +NVSG +F+TWKNTLD+Y DTLLGS EK++FY+E  KEYFFDRDPD+FR +L++Y+TGKLH P++EC+ +YD+EL+FFGI+P+I+GDCCYE+Y+D++REN +R ++D+E  +D KLP + T RE +WRAF+NPQTS  ALVFYYVTGFFIAVSV+ NVVET+ C    N  E   CGE Y  AFFC+DTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRA   + +  QKAR ARI L K  + + F+ +        KRN L  +E  E  +  K+    G   +LLE QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVANLPMPVAPT--EKNKKQDELIVLNVSGRRFQTWKNTLDRYPDTLLGSSEKEFFYNEETKEYFFDRDPDVFRSVLNFYRTGKLHYPRYECILSYDEELAFFGIVPEIIGDCCYEEYKDRKRENAERLMDDQEDNKDSKLPNM-TFRETMWRAFENPQTSTMALVFYYVTGFFIAVSVMTNVVETVPCGSVPNQKEVP-CGERYTVAFFCMDTACVMIFTVEYLMRLFAAPNRYRFMRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSSKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKVQKARLARIRLTKTESSSAFLHS--------KRNGL-FNEALELTSSTKEEQHLGKSSSLLESQHHHLLHCLEKTTNHEFVDE 496          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Medaka
Match: KCND3 (potassium voltage-gated channel subfamily D member 3 [Source:NCBI gene;Acc:101167781])

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 310/496 (62.50%), Postives = 388/496 (78.23%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREA-EDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDDTRQYESD 1592
            GW+P+ N  +P     +   R +E + +N+SG +F+TW+ TLD+Y DTLLGS EKD+FY+E  KEYFFDRDPD FR IL++Y+TGKLH P+HEC+SAYD+EL+FFGI+P+I+GDCCYE+Y+D++REN +R  +D+E  +D KLP + + RE +WRAF+NP TS  ALVFYYVTGFFIA+SV+ NVVET+ C    N  +   CGE Y  AFFC+DTACV+IFT+EYL RL+AAP R +F+RS+MS+IDVVAILPYYIGL+++ N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    T FTSIPASFWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADKR+AQ+K R ARI +AK+ +   F+++K           L+ +  DE    ++Q ++     +LLE QHHHLL CLE  T  E VD+ + YE +
Sbjct:   18 GWMPVANCPMPN-APGDNSKRQDELIILNISGRRFQTWRTTLDRYPDTLLGSTEKDFFYNEETKEYFFDRDPDAFRSILNFYRTGKLHYPRHECISAYDEELTFFGIIPEIIGDCCYEEYKDRKRENLERLQDDQEEIKDMKLPNM-SFRETMWRAFENPHTSTMALVFYYVTGFFIAISVITNVVETVPCGSTFNQKD-MPCGERYTVAFFCIDTACVMIFTVEYLLRLFAAPSRYRFMRSVMSIIDVVAILPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSSTKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKTRMARIRIAKSGSANAFLQSKRNG---MLSELLELTGKDE----EEQKSM-----SLLESQHHHLLHCLEKTTAHEFVDE-QMYEQN 497          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Medaka
Match: ENSORLT00000005345.2 (potassium voltage-gated channel subfamily D member 2 [Source:NCBI gene;Acc:101165880])

HSP 1 Score: 547.74 bits (1410), Expect = 0.000e+0
Identity = 300/490 (61.22%), Postives = 369/490 (75.31%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE--DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRELVDD 1571
            GW+P+    +P P  QE     +  + +NVSG KF+TWK TL++Y DTLLGS E+D+F+ E   EYFFDRDPDIFR+IL++Y+TGKLH P+ EC+SAYD+EL FFGI+P+I+GDCCYE+Y+D++REN DR  +D E +  +   PV  + RE LWRAF+NP TS  ALVFYYVTGFFIA+SV+ANVVET+ C    N ++  +CG+ Y  AFFCLDTACV+IFT EYL RL AAP R KFV+S+MS+IDVVAI+PYYIGL+++ N+ +SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    + FTSIPA+FWYTIVTMTTLGYGDM PKT+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQ+QRA+KR+AQ+K R ARI  AK      ++          K+N L     +E      Q+ +        E QHHHLL CLE  T  E VD+
Sbjct:   18 GWMPVATTPMPIPP-QEKKKTQDGLIILNVSGTKFQTWKTTLERYPDTLLGSTERDFFFHEESNEYFFDRDPDIFRHILNFYRTGKLHYPRQECISAYDEELMFFGIIPEIIGDCCYEEYKDRRRENLDRLQDDEEMDISNEAAPVNLSYREYLWRAFENPHTSTLALVFYYVTGFFIAISVMANVVETVPCGTMPNRSKEVSCGDRYALAFFCLDTACVMIFTFEYLLRLIAAPSRYKFVKSVMSVIDVVAIMPYYIGLVMTDNDQVSGAFVTLRVFRVFRIFKFSRHSAGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSAHSKFTSIPAAFWYTIVTMTTLGYGDMVPKTIVGKVFGSICSLSGVLVIALPVPVIVSNFSRIYHQSQRAEKRRAQRKTRLARIRAAKIRGTNAYM--------HFKQNGLLIDSLEEASKKAGQALVGKAASPPFESQHHHLLHCLEKTTNHEFVDE 498          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Medaka
Match: kcnd1 (potassium voltage-gated channel subfamily D member 1 [Source:NCBI gene;Acc:101171558])

HSP 1 Score: 545.043 bits (1403), Expect = 0.000e+0
Identity = 298/465 (64.09%), Postives = 369/465 (79.35%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAE---DRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNK--------IQADER---RKRNCLQHSENDEDYT 1460
            GW+PL   ++PKP + +   RS+E + +NVSG +F+TWKNTLD+Y DTLLGS EK++F++E  +EYFFDRDP++FR+IL++Y+TGKLH P++EC+ A+D+EL+F+GI+P+I+GDCC E+YRD+++EN +R  ED EA    D  LP   T RE+LWRAF+NP TS  ALVFYYVTGFFIAVSV+ANVVET+ C     + +   CGE Y+ AFFC+DTACVLIFT EYL RL+AAP R KF+RS+MS+IDVVAI+PYYIGL++ +N D+SGAFV LRVFRVFRI KFSRHS GLRILGYTLKSCASELGFLLFSL+MA+IIFAT+++YAEK    +TFTSIPASFWYTIVTMTTLGYGDM P T+ GK+ G ICSLSG+LVIALPVPVIVSNFSRIYHQNQRADK +AQQK R ARI +AK      F++ K         ++D     RKR   +HS+ D D T
Sbjct:   18 GWLPLAKKTMPKPPV-DNSSRSDEILYVNVSGVRFQTWKNTLDRYPDTLLGSSEKEFFFNEETQEYFFDRDPEMFRHILNFYRTGKLHYPRYECIQAFDEELAFYGIVPEIIGDCCMEEYRDRKKENQERLAEDSEANEGTDAPLPPDSTSRERLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCRPPKGSVKDLPCGEKYQLAFFCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSVIDVVAIMPYYIGLVMPENEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTKGSTFTSIPASFWYTIVTMTTLGYGDMVPNTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKMRAQQKVRLARIRMAKKGTTNAFLQYKEDRGLGLLRESDSSGFLRKRR--KHSDRDSDST 479          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Planmine SMEST
Match: SMESG000081212.1 (SMESG000081212.1)

HSP 1 Score: 907.901 bits (2345), Expect = 0.000e+0
Identity = 482/483 (99.79%), Postives = 482/483 (99.79%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGR 1556
            GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTGKLLGGICSLSGLLVIALPVPVIVSNFSRIYHQNQRADKRKAQQKARKARIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVT R
Sbjct:   17 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTGKLLGGICSLSGLLVIALPVPVIVSNFSRIYHQNQRADKRKAQQKARKARIALAKNYNCTNFIKNKIQADERRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTVR 499          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Planmine SMEST
Match: SMESG000081212.1 (SMESG000081212.1)

HSP 1 Score: 737.258 bits (1902), Expect = 0.000e+0
Identity = 354/354 (100.00%), Postives = 354/354 (100.00%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGY 1169
            GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGY
Sbjct:   17 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGY 370          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Planmine SMEST
Match: SMESG000054100.1 (SMESG000054100.1)

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 366/491 (74.54%), Postives = 413/491 (84.11%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYHXXXXXXXXXXXXXXXXXXIALAKNYNCTNFIKNKIQADERRK-RNCLQHSENDEDYTYDKQSNIN-GVKETLLEIQHHHLLSCLEMVTGRELVDDT 1574
            GW+PL    LP       D+ S++KV INVSG+KFETWKNTL+K++DTLLGSDEKD+F+DE EKEYFFDRDP+IFR+ILSYYQTGKLHCPK ECV+AYDDELSFFGILPDIMGDCCYEDYRDKQREN +R+IE  + + RK PV KTIREK+W+ F+ P+ S  A+V YYVTGFFIAVSV ANV ETISC  +   ++S +CGE YE  FFCLDT CVLIFT+EY ARL+AAP R+KF+RSIMS+IDVVAI+PYYIGL +SKNN MSGAFVILRVFRVFRIIKFSRHS GLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKS   T FTSIPASFWYTIVTMTTLGYGDMTPKTV GK+LGGICSLSGLLVIALPVPVIVSNFSRIYHQNQRADKRKAQQKARKARI LAK YN  NFI+NK  AD +R+ R+    + +DE+        I+   +++LL+IQHHHLL+CLE VT   LVDDT
Sbjct:   17 GWIPLCKKQLPSINTGLADYNSDDKVIINVSGYKFETWKNTLEKFNDTLLGSDEKDFFWDEAEKEYFFDRDPEIFRFILSYYQTGKLHCPKQECVNAYDDELSFFGILPDIMGDCCYEDYRDKQRENIERSIETPDVDARKRPVGKTIREKMWQCFEYPRDSTLAMVVYYVTGFFIAVSVFANVFETISCGMDPQFDKSISCGEMYEGPFFCLDTGCVLIFTVEYFARLFAAPVRVKFMRSIMSIIDVVAIVPYYIGLGLSKNNSMSGAFVILRVFRVFRIIKFSRHSSGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSVPNTLFTSIPASFWYTIVTMTTLGYGDMTPKTVVGKILGGICSLSGLLVIALPVPVIVSNFSRIYHQNQRADKRKAQQKARKARIILAKQYNSINFIQNKNNADHKRRIRSGESRTSDDENSNPSNNVQIHEHWQDSLLKIQHHHLLTCLEQVTNCHLVDDT 507          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Planmine SMEST
Match: SMESG000037357.1 (SMESG000037357.1)

HSP 1 Score: 481.1 bits (1237), Expect = 1.002e-160
Identity = 248/398 (62.31%), Postives = 316/398 (79.40%), Query Frame = 3
Query:  108 GWVPLTNHSLP---KPTIQETDHRSEEKVKINVSGFKFETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIEDREAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIYH 1292
            GW+PL+   +P     +++      + KV IN+SG +FE + ++L++Y +TLLGS E+DYFYDE   EY+FDRDPDIFRYILSYY+ G LH PK ECV+A+D+EL +F I  D++ DCCYEDY+D ++EN++R   ++     K    +T R+KLW AF+NP+ S ++LV YYVTGFFIA+SVLANV+ET+   F    + S +CGE +E+AFFCLD+ CV IFT+EY ARLYAAP+R KF +S+MSLIDVVAILP+YIGLL+  N D+SGAFV LRVFRVFRI KFSRHS  LRILGYTL+SCASELGFLLFS++MA+IIFAT++YYAEK + KT F SIP +FWYT VTMTTLGYGDM P ++ GK++GGICSL+G+L+IALP+PVIVSNFSRIYH
Sbjct:   17 GWMPLSKSPMPFNQTISMENLSLHCDSKVIINISGKRFEVFLSSLNRYPNTLLGSCERDYFYDEENDEYYFDRDPDIFRYILSYYRCGHLHFPKQECVAAFDEELCYFRISSDVIQDCCYEDYQDCRKENYERFFIEKPPVTEKDLNNQTNRQKLWHAFENPEASTSSLVIYYVTGFFIAISVLANVIETVPYSFKVEIDRSVSCGEQFEQAFFCLDSGCVAIFTVEYFARLYAAPRRWKFFKSVMSLIDVVAILPFYIGLLMPNNKDVSGAFVTLRVFRVFRIFKFSRHSERLRILGYTLQSCASELGFLLFSMTMAIIIFATVMYYAEKFEPKTKFLSIPDAFWYTTVTMTTLGYGDMVPTSIIGKIVGGICSLAGVLMIALPIPVIVSNFSRIYH 414          
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Planmine SMEST
Match: SMESG000023423.1 (SMESG000023423.1)

HSP 1 Score: 404.831 bits (1039), Expect = 1.114e-133
Identity = 232/415 (55.90%), Postives = 300/415 (72.29%), Query Frame = 3
Query:  108 GWVPLTNHSLPKPT--IQETD----------HRSEEKVKINVSGFKFETWKNTLDKYSDTLLG-SDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQTGKLHCPKHECVSAYDDELSFFGILPDIMGD--CCYEDYRDKQRENHDRTIEDREAE----DRKLP--VLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANVVETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPKRMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKFSRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTTFTSIPASFWYTIVTMTTLGYGDMTPKTVTXXXXXXXXXXXXXXXXXXXXXXXXSNFSRIY 1289
            GW PL++   P     I +TD             E ++ INVSG KFE  +  +D+Y  TLLG S +++ ++D+  KEYFFDRDP+IFRY+L +Y+ G  H  ++EC +++++E++FF I  D++G   CCYE Y D  +E  +R  +  +       RK     LK IR K+W AF+NP +S+ A V YYV+GFFIA SV ANV+ETI C  +  T  S   G  YE+ F C D ACV++FT+EYL RL+A+P+ ++F RS+MS+IDVVAILP+YIGL++  N ++SGAF  LRVFRVFRI KFSRHS GLRILG+TL+SCASELGFLLFSL+MA++IF+T+IYY EKS   T FTSIPA+FWYTIVTMTTLGYGDM PKT+ G+L+G ICSLSG+LVIALPVPVIVSNFSRIY
Sbjct:   19 GWSPLSSKPFPSQFQHICDTDLTFDIDNKGRPSIERRMLINVSGRKFEISQYLVDRYPQTLLGNSKDREKYFDQELKEYFFDRDPEIFRYVLIFYRQGYTHFARNECSASFEEEMNFFRI--DMIGLNFCCYEVYEDCHQETIERMTDINQELLPDLSRKFDNLFLKNIRFKIWEAFENPSSSLVAQVIYYVSGFFIAASVFANVLETIPCSTSTETGASINFGVQYERVFSCSDAACVILFTVEYLFRLFASPEPLRFFRSVMSMIDVVAILPFYIGLMMQDNKEVSGAFTTLRVFRVFRIFKFSRHSAGLRILGHTLQSCASELGFLLFSLTMAIVIFSTIIYYLEKSVQDTNFTSIPAAFWYTIVTMTTLGYGDMVPKTLLGRLIGSICSLSGVLVIALPVPVIVSNFSRIY 431          
The following BLAST results are available for this feature:
BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCND10.000e+062.63potassium voltage-gated channel subfamily D member... [more]
KCND20.000e+061.71potassium voltage-gated channel subfamily D member... [more]
KCND30.000e+059.84potassium voltage-gated channel subfamily D member... [more]
KCND30.000e+059.84potassium voltage-gated channel subfamily D member... [more]
KCND30.000e+061.71potassium voltage-gated channel subfamily D member... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shl-10.000e+060.79SHaL family of potassium channels [Source:UniProt... [more]
shk-14.878e-5431.54Potassium voltage-gated channel protein shk-1 [So... [more]
shk-14.878e-5431.54Potassium voltage-gated channel protein shk-1 [So... [more]
shk-15.442e-5431.27Potassium voltage-gated channel protein shk-1 [So... [more]
shk-11.000e-5331.00Potassium voltage-gated channel protein shk-1 [So... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Shal0.000e+065.10gene:FBgn0005564 transcript:FBtr0112853[more]
Shal0.000e+062.87gene:FBgn0005564 transcript:FBtr0333273[more]
Shal0.000e+065.29gene:FBgn0005564 transcript:FBtr0074973[more]
Sh1.244e-6537.96gene:FBgn0003380 transcript:FBtr0302903[more]
Sh1.244e-6537.96gene:FBgn0003380 transcript:FBtr0089661[more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnd30.000e+062.40potassium voltage-gated channel, Shal-related subf... [more]
kcnd30.000e+061.34potassium voltage-gated channel, Shal-related subf... [more]
kcnd20.000e+060.56potassium voltage-gated channel, Shal-related subf... [more]
kcnd20.000e+060.56potassium voltage-gated channel, Shal-related subf... [more]
kcnd10.000e+067.36potassium voltage-gated channel, Shal-related subf... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCND20.000e+060.94potassium voltage-gated channel subfamily D member... [more]
kcnd30.000e+060.91potassium channel, voltage gated Shal related subf... [more]
kcnd30.000e+062.73potassium channel, voltage gated Shal related subf... [more]
ENSXETT00000036803.10.000e+067.36potassium channel, voltage gated Shal related subf... [more]
KCNA53.632e-6940.05potassium channel, voltage gated shaker related su... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kcnd10.000e+062.07potassium voltage-gated channel, Shal-related fami... [more]
Kcnd20.000e+061.51potassium voltage-gated channel, Shal-related fami... [more]
Kcnd30.000e+059.84potassium voltage-gated channel, Shal-related fami... [more]
Kcnd30.000e+061.71potassium voltage-gated channel, Shal-related fami... [more]
Kcnd30.000e+061.71potassium voltage-gated channel, Shal-related fami... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P17971|KCNAL_DROME0.000e+065.10Potassium voltage-gated channel protein Shal OS=Dr... [more]
sp|Q9NSA2|KCND1_HUMAN0.000e+062.63Potassium voltage-gated channel subfamily D member... [more]
sp|Q03719|KCND1_MOUSE0.000e+062.07Potassium voltage-gated channel subfamily D member... [more]
sp|Q9NZV8|KCND2_HUMAN0.000e+061.71Potassium voltage-gated channel subfamily D member... [more]
sp|Q8HYZ1|KCND2_MUSPF0.000e+061.51Potassium voltage-gated channel subfamily D member... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3S1C1P20.000e+067.01BTB domain-containing protein OS=Elysia chlorotica... [more]
A0A1I8JFA10.000e+065.66BTB domain-containing protein OS=Macrostomum ligna... [more]
A0A267E2A40.000e+065.66BTB domain-containing protein OS=Macrostomum ligna... [more]
A0A1I8JED20.000e+065.66BTB domain-containing protein OS=Macrostomum ligna... [more]
A0A1I8IL690.000e+066.11BTB domain-containing protein OS=Macrostomum ligna... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000026139.20.000e+061.71potassium voltage-gated channel subfamily D member... [more]
kcnd30.000e+060.57potassium voltage-gated channel subfamily D member... [more]
kcnd10.000e+067.59potassium voltage-gated channel subfamily D member... [more]
kcnd10.000e+067.59potassium voltage-gated channel subfamily D member... [more]
kcnd10.000e+068.59potassium voltage-gated channel subfamily D member... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000004235.18.416e-6432.96pep scaffold:Pmarinus_7.0:GL476413:398954:411573:-... [more]
KCNA31.240e-6238.52potassium voltage-gated channel subfamily A member... [more]
kcnc1a1.381e-6135.88potassium voltage-gated channel, Shaw-related subf... [more]
KCNA38.742e-6035.68potassium voltage-gated channel subfamily A member... [more]
kcna1b1.129e-5835.90potassium voltage-gated channel, shaker-related su... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO318031.092e-16254.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO313114.974e-10946.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO475802.308e-10146.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO318071.075e-9844.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461568.690e-8942.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnd30.000e+062.35potassium voltage-gated channel subfamily D member... [more]
kcnd30.000e+063.21potassium voltage-gated channel subfamily D member... [more]
KCND30.000e+062.50potassium voltage-gated channel subfamily D member... [more]
ENSORLT00000005345.20.000e+061.22potassium voltage-gated channel subfamily D member... [more]
kcnd10.000e+064.09potassium voltage-gated channel subfamily D member... [more]
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BLAST of Potassium voltage-gated channel protein Shal-like Protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000081212.10.000e+099.79SMESG000081212.1[more]
SMESG000081212.10.000e+0100.00SMESG000081212.1[more]
SMESG000054100.10.000e+074.54SMESG000054100.1[more]
SMESG000037357.11.002e-16062.31SMESG000037357.1[more]
SMESG000023423.11.114e-13355.90SMESG000023423.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029282 ID=SMED30029282|Name=Potassium voltage-gated channel protein Shal-like Protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2318bp
TTTAAATTTTGTTGAAAAATGTTCTCAAAGTTAATTTGAATTAACTTAAA
ACAACTCAAATGGCTTCAATTGCTGCTTTGTTGCCACTAGCAAGAAGTGC
TGCACTTGGATGGGTACCTTTAACAAATCATTCTTTGCCAAAACCCACAA
TTCAAGAAACAGATCACCGAAGCGAAGAAAAAGTCAAAATCAATGTCAGC
GGTTTCAAATTTGAAACTTGGAAAAACACACTGGACAAATATTCTGACAC
TTTGCTCGGTTCAGACGAAAAGGATTATTTCTATGATGAAGTGGAAAAGG
AATATTTTTTCGATCGTGATCCTGACATTTTTAGATACATTCTCTCATAT
TATCAAACTGGTAAATTGCATTGCCCAAAGCACGAATGCGTTAGTGCATA
CGACGATGAACTGTCGTTTTTCGGAATTCTGCCGGATATAATGGGAGATT
GCTGCTATGAAGATTACCGAGACAAACAACGGGAAAATCACGACCGAACT
ATTGAAGACCGAGAAGCTGAAGACAGAAAACTTCCAGTATTGAAAACAAT
ACGAGAAAAACTATGGAGAGCTTTTGATAATCCTCAAACATCAGTAGCAG
CGTTGGTGTTCTATTACGTAACAGGATTTTTTATTGCAGTTTCTGTGTTG
GCAAATGTTGTCGAAACGATTTCGTGTGATTTCAACGCTAATACGAACGA
ATCAAAAACGTGCGGAGAAACATATGAAAAAGCATTTTTCTGTTTAGACA
CAGCCTGTGTTCTGATATTTACGTTAGAATATCTCGCCCGGCTTTATGCA
GCACCGAAAAGAATGAAATTCGTCCGTTCAATAATGAGTCTTATCGATGT
CGTGGCCATTCTTCCGTATTACATAGGTTTGTTAATTTCGAAAAATAATG
ACATGAGCGGAGCATTCGTCATTCTTCGAGTATTTCGCGTATTCAGAATT
ATAAAATTTTCCCGACACAGCATGGGGTTACGGATTCTGGGTTACACTCT
GAAATCATGTGCATCTGAATTGGGATTTTTATTGTTTTCTCTCTCAATGG
CTGTAATTATTTTTGCAACAATGATTTATTACGCAGAGAAATCGGATTTA
AAAACCACATTCACAAGCATTCCAGCTTCTTTCTGGTATACAATTGTTAC
AATGACTACTCTGGGATATGGAGACATGACTCCAAAAACAGTTACTGGAA
AATTGCTTGGTGGTATTTGCTCATTATCTGGACTTCTTGTAATAGCGCTG
CCAGTTCCTGTTATTGTGTCGAACTTTAGCAGAATATATCATCAGAATCA
ACGTGCAGATAAAAGAAAAGCTCAACAAAAAGCTCGCAAAGCTCGAATAG
CTCTAGCCAAAAATTACAATTGTACAAACTTCATTAAAAACAAAATACAA
GCAGATGAAAGACGTAAAAGGAACTGTCTTCAACATTCAGAAAATGATGA
AGATTATACTTACGACAAGCAATCAAACATCAATGGAGTTAAAGAAACCT
TATTAGAGATTCAGCACCATCATTTACTTTCATGTTTAGAAATGGTCACA
GGACGTGAACTTGTTGATGACACCCGTCAATACGAGTCCGACAATCAATC
ATCCATTCGTGATAGTTACTCATCCCCTTTAATTCGAAAATCTACAAATA
GAAGTCGATCGTCGAATAATCGTATAAAATTTCGTCCATCACTTGAGGGG
GTCCATCATGGGATAGAATCAAAACTGTCCGGTTATTCATCATGCATATG
TTTCAGATGCAAGCGAAAAAAAAACAAAAAAAGGTCTAATGATGATGAAG
ATGAAGATTTAAATTATTATCAAAATCAGTTTCAGTTAAGACACCTGTCC
AATGTCGATCATTCTCCGACGAGAAATTCAGGGGGATCAGATGACAATTA
CATAGTTACTCCTGCAATTACATTAAAATCGGATATCTCACATCAGTTAG
CTGATAGCAGAAATTCGTTGGAGGAAACTTCAAACCAATGTTTATACAAA
CCAAGTCCAATCATCAAATTTTCTAGGATACAGTCCATAGATTATAACTA
TAATGCTCGAAGCCAAAGTTTTCAATGTTCGAATATGTCAGTCAATTCCC
AGGATCAAACGCACACTGATGAGAAACAAGTCAAGTTTGCCAATTTCCAA
TAGAGGTTAAACAACTAAAGTTCAAGAAATAAAAATTGTAAAAATAAAAA
GTTTCACTCATATTTTTATATAAAACATGTTGCTTATTTGGAATATAATT
TTCTTGTTCTTTTTTTATAAAATTACTGATCTCTCAATAGACTCTGTGAA
GTTTTGCATTTATTTAAG
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protein sequence of SMED30029282-orf-1

>SMED30029282-orf-1 ID=SMED30029282-orf-1|Name=SMED30029282-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=698bp
MASIAALLPLARSAALGWVPLTNHSLPKPTIQETDHRSEEKVKINVSGFK
FETWKNTLDKYSDTLLGSDEKDYFYDEVEKEYFFDRDPDIFRYILSYYQT
GKLHCPKHECVSAYDDELSFFGILPDIMGDCCYEDYRDKQRENHDRTIED
REAEDRKLPVLKTIREKLWRAFDNPQTSVAALVFYYVTGFFIAVSVLANV
VETISCDFNANTNESKTCGETYEKAFFCLDTACVLIFTLEYLARLYAAPK
RMKFVRSIMSLIDVVAILPYYIGLLISKNNDMSGAFVILRVFRVFRIIKF
SRHSMGLRILGYTLKSCASELGFLLFSLSMAVIIFATMIYYAEKSDLKTT
FTSIPASFWYTIVTMTTLGYGDMTPKTVTGKLLGGICSLSGLLVIALPVP
VIVSNFSRIYHQNQRADKRKAQQKARKARIALAKNYNCTNFIKNKIQADE
RRKRNCLQHSENDEDYTYDKQSNINGVKETLLEIQHHHLLSCLEMVTGRE
LVDDTRQYESDNQSSIRDSYSSPLIRKSTNRSRSSNNRIKFRPSLEGVHH
GIESKLSGYSSCICFRCKRKKNKKRSNDDEDEDLNYYQNQFQLRHLSNVD
HSPTRNSGGSDDNYIVTPAITLKSDISHQLADSRNSLEETSNQCLYKPSP
IIKFSRIQSIDYNYNARSQSFQCSNMSVNSQDQTHTDEKQVKFANFQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR003968K_chnl_volt-dep_Kv
IPR028325VG_K_chnl
IPR003975K_chnl_volt-dep_Kv4
IPR000210BTB/POZ_dom
IPR005821Ion_trans_dom
IPR021645Shal-type_N
IPR003131T1-type_BTB
IPR027359Volt_channel_dom_sf
IPR024587K_chnl_volt-dep_Kv4_C
IPR011333SKP1/BTB/POZ_sf
Vocabulary: molecular function
TermDefinition
GO:0005249voltage-gated potassium channel activity
GO:0005515protein binding
GO:0005216ion channel activity
GO:0005244voltage-gated ion channel activity
GO:0005250A-type (transient outward) potassium channel activity
GO:0005267potassium channel activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006813potassium ion transport
GO:0055085transmembrane transport
GO:0006811ion transport
GO:0051260protein homooligomerization
GO:0006810transport
GO:0034765regulation of ion transmembrane transport
GO:0061337cardiac conduction
GO:0071805potassium ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0008076voltage-gated potassium channel complex
GO:0016020membrane
GO:0005575cellular_component
GO:0005886plasma membrane
GO:0016021integral component of membrane
GO:0030425dendrite
GO:0042995cell projection
GO:0043025neuronal cell body
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 411..431
NoneNo IPR availablePRINTSPR00169KCHANNELcoord: 291..317
score: 60.25
coord: 175..203
score: 37.79
coord: 320..343
score: 52.1
coord: 81..100
score: 59.28
coord: 228..251
score: 41.02
coord: 254..274
score: 54.25
coord: 380..406
score: 64.26
coord: 351..373
score: 71.36
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 304..414
e-value: 1.7E-29
score: 103.7
NoneNo IPR availableGENE3DG3DSA:3.30.710.10coord: 1..143
e-value: 5.6E-49
score: 167.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 512..538
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 504..538
NoneNo IPR availablePANTHERPTHR11537:SF182POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 3coord: 29..588
NoneNo IPR availableCDDcd18420BTB_POZ_Shal-likecoord: 6..143
e-value: 2.79634E-78
score: 244.372
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..17
score: 0.523
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 181..408
NoneNo IPR availableTMHMMTMhelixcoord: 254..276
NoneNo IPR availableTMHMMTMhelixcoord: 382..404
NoneNo IPR availableTMHMMTMhelixcoord: 179..201
NoneNo IPR availableTMHMMTMhelixcoord: 350..372
NoneNo IPR availableTMHMMTMhelixcoord: 321..343
IPR003975Potassium channel, voltage dependent, Kv4PRINTSPR01497SHALCHANNELcoord: 315..334
score: 89.77
coord: 177..191
score: 87.27
coord: 158..172
score: 37.58
coord: 426..442
score: 36.9
coord: 412..423
score: 84.47
coord: 217..233
score: 74.87
coord: 67..80
score: 48.7
IPR003968Potassium channel, voltage dependent, KvPRINTSPR01491KVCHANNELcoord: 320..334
score: 54.22
coord: 296..304
score: 70.93
coord: 81..91
score: 69.55
coord: 391..402
score: 78.68
IPR000210BTB/POZ domainSMARTSM00225BTB_4coord: 40..139
e-value: 1.6E-17
score: 74.2
IPR021645Shal-type voltage-gated potassium channels, N-terminalPFAMPF11601Shal-typecoord: 2..29
e-value: 4.6E-7
score: 29.2
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 183..413
e-value: 2.3E-36
score: 125.3
IPR027359Voltage-dependent channel domain superfamilyGENE3DG3DSA:1.20.120.350coord: 153..303
e-value: 3.9E-37
score: 129.2
IPR024587Potassium channel, voltage dependent, Kv4, C-terminalPFAMPF11879DUF3399coord: 452..577
e-value: 2.4E-8
score: 34.3
IPR003131Potassium channel tetramerisation-type BTB domainPFAMPF02214BTB_2coord: 42..131
e-value: 1.7E-26
score: 92.4
IPR028325Voltage-gated potassium channelPANTHERPTHR11537VOLTAGE-GATED POTASSIUM CHANNELcoord: 29..588
IPR011333SKP1/BTB/POZ domain superfamilySUPERFAMILYSSF54695POZ domaincoord: 40..143