slc6a-1

Overview
Nameslc6a-1 (AKN21421.1)
Smed IDSMED30029272
Length (bp)2006
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of slc6a-1 (SMED30029272) t-SNE clustered cells

Violin plots show distribution of expression levels for slc6a-1 (SMED30029272) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc6a-1 (SMED30029272) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc6a-1 (SMED30029272) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30029272

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 14

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pigment cellSMED30029272h1SMcG0001252 SmedASXL_012823SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017
whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30029272h1SMcG0001252 Contig49260newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029272h1SMcG0001252 Contig49260uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029272h1SMcG0001252 Contig13069uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029272h1SMcG0001252 Contig13069newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029272h1SMcG0001251 Contig13069uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029272h1SMcG0001251 Contig13069newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30029272h1SMcG0001252 dd_Smed_v4_8169_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30029272h1SMcG0001252 dd_Smed_v4_8169_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30029272h1SMcG0001252 dd_Smed_v4_8169_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30029272h1SMcG0001252 dd_Smed_v4_8169_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30029272h1SMcG0001252 dd_Smed_v4_8169_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30029272h1SMcG0001252 dd_Smed_v6_8169_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
pigment cellSMED30029272h1SMcG0001252 dd_Smed_v6_8169_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of slc6a-1 vs. Ensembl Human
Match: SLC6A1 (solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 292/594 (49.16%), Postives = 400/594 (67.34%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL-EILRDVFQPTN 1895
            S +  E+ +A+ K +     +         R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AWIL YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC +SYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V IFS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       S K    ++ +   D+ +P N
Sbjct:   14 STEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSMVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. Ensembl Human
Match: SLC6A1 (solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 292/594 (49.16%), Postives = 400/594 (67.34%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL-EILRDVFQPTN 1895
            S +  E+ +A+ K +     +         R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AWIL YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC +SYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V IFS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       S K    ++ +   D+ +P N
Sbjct:   14 STEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSMVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. Ensembl Human
Match: SLC6A1 (solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 292/594 (49.16%), Postives = 400/594 (67.34%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL-EILRDVFQPTN 1895
            S +  E+ +A+ K +     +         R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AWIL YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC +SYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V IFS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       S K    ++ +   D+ +P N
Sbjct:   14 STEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSMVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. Ensembl Human
Match: SLC6A1 (solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 292/594 (49.16%), Postives = 400/594 (67.34%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL-EILRDVFQPTN 1895
            S +  E+ +A+ K +     +         R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AWIL YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC +SYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V IFS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       S K    ++ +   D+ +P N
Sbjct:   14 STEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSMVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. Ensembl Human
Match: SLC6A1 (solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 292/594 (49.16%), Postives = 400/594 (67.34%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL-EILRDVFQPTN 1895
            S +  E+ +A+ K +     +         R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AWIL YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC +SYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V IFS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       S K    ++ +   D+ +P N
Sbjct:   14 STEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSMVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. Ensembl Celegans
Match: snf-11 (Transporter [Source:UniProtKB/TrEMBL;Acc:G5EF43])

HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0
Identity = 307/601 (51.08%), Postives = 418/601 (69.55%), Query Frame = 3
Query:  204 HREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDN-NVTALCNNSDNGILDSKM-----------------KMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQH--RKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYK--DKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNE--DITDKKENIQMI 1934
             REQWSS  DF++S IG  +GLGN+WRFPYLCY+NGGGAFLIPY ++LVF G P+ +LE   GQ+ S+GGLG++K C +FKGVG AA +MAFWL+IYYIV+L++A  Y++NSFT++ +PW +C+H WNT  C S+   +    N +     + K+                 KMN++       +  SPV EFW   VLG SSG+E PG I+W LAL LL  WI+CY CI+KGVKWTGK+VY TA FPY++L CL IRG+TL G+  G++FYLKP+ SKL ESKVW+D  TQ+FFSYGLGLG  +ALGSYNK+ NN ++ AL +  VN+ TS+FAGFV+FS +GFMA QQ K V +V ++G GL+FL YPS + QLP + FWS LFFLM++FLG+DSQFCT+EGF TAIIDE+P   R+   R++ + V+C +SYLIGL+ VT+GG YVF+LFD Y+ASG ALL+L+F +CIA SW  GI+R+ +    M+G+  S WWKFCW+  +P VC  VL+F ++ Y+ ++    + +Y  W H  G FL+LSS++ IPGY  +  F      K   ++ E ++ + +P  E     +  EN++++
Sbjct:    9 EREQWSSWADFIMSCIGYAIGLGNVWRFPYLCYQNGGGAFLIPYCISLVFCGAPLFILETSWGQLMSVGGLGMFKICPIFKGVGIAAAVMAFWLNIYYIVVLSWAATYLYNSFTMSDVPWKNCDHAWNTPNCRSEYVKIPCDSNRTIAEFFNVKVLTHDHIHEYKKQFFVGEKMNWTVCSAADLSVVSPVKEFWNHRVLGISSGLENPGGIRWDLALFLLLVWIICYLCIFKGVKWTGKVVYITASFPYMMLFCLLIRGLTLEGAGVGLEFYLKPDFSKLLESKVWVDAVTQVFFSYGLGLGALVALGSYNKFNNNVYKQALTVCFVNSGTSVFAGFVIFSFIGFMATQQEKSVAEVAQAGPGLLFLAYPSGILQLPYTQFWSCLFFLMVLFLGVDSQFCTMEGFFTAIIDEFPQIRRKKYGREIFVGVICVISYLIGLTTVTEGGFYVFQLFDFYAASGWALLWLLFFECIAISWSLGIDRWYEHMKSMIGYYPSAWWKFCWVFATPSVCFGVLLFGLIKYQPLRIDAYNYDYPVWGHIFGWFLSLSSMLCIPGYAIWIWF------KTPGTVQEKIKLLCRPDIEIKGAMENAENLELV 603          
BLAST of slc6a-1 vs. Ensembl Celegans
Match: snf-3 (Sodium- and chloride-dependent betaine transporter [Source:UniProtKB/Swiss-Prot;Acc:G5EBN9])

HSP 1 Score: 416.001 bits (1068), Expect = 1.795e-137
Identity = 237/613 (38.66%), Postives = 359/613 (58.56%), Query Frame = 3
Query:  108 DLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKD-KEYATWAHAIGIFLALSSVIMIPGYIFYYTF---QQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMI 1934
            D + AK++E S  S +                 R QW+ K DF++S +   VGLGN+WRFPYLCY+NGGG+FL+ Y++    A VPI L+E+ +GQ    G + +W  C +F+GVG   V++AF    Y+ VI+A+A  YM +S      PW  CN+ WN   C     VT   N ++   + + +     H  T        V +FWE+ VL ++  I   G IQW+L   +  AW++ YF +WKG+    K VYF ALFPYVL+  L IRG+TL G+  GI FYLKPN ++L ++ VW D  TQ+F+SYG+G G  IALGS+NK+ +NC +DA+ +  +N  TS+ AGF VFS++G+M+H   K++ ++VK G GL FL YP   + LP    +++LFFLMI  LGLDSQ C +EG  TA+ D +P   R+++K  L + C   + IG+ MVT  G++   LFD Y ASG ALLF++F + +  ++ +G +   K  ++M+G ++ K  ++ W   +P   + + +F V+ Y  VKY D K++  WA+A G FL+  S+++IPGY  YY F   + +   +  +  L +      P  +++ +  E ++ I
Sbjct:   12 DEAKAKELEQSQHSEEPD---------------RGQWTGKFDFLMSMVAYAVGLGNVWRFPYLCYKNGGGSFLVVYMIFFCLAAVPIFLMEVTVGQYLQKGAMEMWLMCPLFRGVGIGNVVIAFMCIAYFCVIVAWAMFYMISSIAW-VFPWETCNNYWNDATC-----VTGKENFTELARIKALVASAGGHTQTS-------VEQFWEKRVLHDTGDISEFGGIQWELFFIMAAAWLIVYFALWKGITQARKFVYFCALFPYVLIFILLIRGLTLEGAGTGIYFYLKPNATRLLDTAVWKDAGTQVFYSYGVGFGALIALGSHNKFNHNCFKDAITMCFINGCTSITAGFAVFSILGYMSHVAQKDISEIVKPGVGLAFLAYPEVASNLPMKQVFAVLFFLMITILGLDSQVCMMEGLFTALEDAFP-ILRKYKKQSLGIFCLFFFCIGIPMVTHSGSHWLTLFDAYGASGYALLFVVFFEVVGLAYGFGAHNIRKALHEMIGVTLPKGIEYVWKFCAPATSLVLFVFCVVYYHPVKYPDGKDFPFWANAFGWFLSSCSMVVIPGYAIYYLFFTNKHLTLKERVRKGLNLDGSFESPAKKNLVNNAEELKFI 595          
BLAST of slc6a-1 vs. Ensembl Celegans
Match: dat-1 (Sodium-dependent dopamine transporter [Source:UniProtKB/Swiss-Prot;Acc:Q03614])

HSP 1 Score: 407.142 bits (1045), Expect = 6.636e-134
Identity = 231/625 (36.96%), Postives = 362/625 (57.92%), Query Frame = 3
Query:  108 DLSSAKQMESSIASSKSQLGDKTL-----TSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDN---NVTALCNNSDNGILDSKMKMNFSHL------CTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPG---YIFYYTFQQIISHKNEKSILEILRDVFQ------PTNEDITD 1910
             L      +  I  + + + + TL      +TE  D  REQWS K+DF+LS +G  V LGNIWRFPYLC++NGGG FLIPY + ++  GVP+  +EL +GQ    G +  W + C +FKG+GY  ++ AF++  +Y VILA+   Y++ SF+ N LPW+ CN+ +N+  C   +   + TA+C +++  +   K+     +         E  A NS V+             +   G+++W +AL+L   +++CYF +WKG+  +GK+V+FTALFPYV+L  LFIRG+TL G   GI++YL+PN   LK   VW D ATQ+FFS G G G  +A  SYN + NN + DAL    +N +TS  +GFV+FSV+G+M+ +  K ++ V + G GL+F+VYP AL+ +P + FWS+LFFLM++ LGLDS F   E  +T + DE+P   +++R++ +  +     +IG++M T+GG  +      Y  +   LL  +FC+ +  ++ YG+ +F+ D  +M+GF    +WKFCW   +P + + ++  + ++Y+ + Y+D  Y T A+ IGI  ALS    IP    Y F       IS K ++  +   +   Q      PT +  +D
Sbjct:    2 QLVPTDDPDEKIGRTSNGMQNATLPIDGPVNTEPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFN-LPWASCNNSYNSPACYEPHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFLGLHEANAPNSHVIR-----------SVTDLGNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCATSFLSGFVIFSVLGYMSCKSGKPIEAVAQEGPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFP-ILKKNREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTT-WGLLIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRPGNYWKFCWSCAAPFILLSMITSNFINYQALTYQDYTYPTAANVIGIIFALSGASFIPLVGIYKFVNARGNTISEKWQRVTMPYRKRPNQTEYIPIPTTQPHSD 612          
BLAST of slc6a-1 vs. Ensembl Celegans
Match: mod-5 (Transporter [Source:UniProtKB/TrEMBL;Acc:Q9N3C7])

HSP 1 Score: 362.844 bits (930), Expect = 5.164e-116
Identity = 208/546 (38.10%), Postives = 324/546 (59.34%), Query Frame = 3
Query:  207 REQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTL---NPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVL--GESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVV-KSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVL--SYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYY 1817
            R++W++K++F+L+ +G  V LGNIWRFP +CY++GGGAFLIPY + L+  G+P+  +EL++GQ    G + +W K C +F+G+GY    +  +++I+Y  I+A A  +   S +    + +PW+ C +PWNT  C+ D NVT     S NG                     +P  E++   VL   +S+G +  G ++  +A+ LL  +I+ YF +WKG + +GKIV+ TA  PY++L  L IRG+ L G+  G+ +Y+ P+  KLK+  VW   ATQIFFS G G G  +AL SYN + NNC+RDA+   ++N +TS F+G VVFS +G+M+   NK + +VV +    LIF+VYP ALA +  S FWS +FF+M+I LG+DS F  +E F+T   DE      ++RK  + V+C + Y +    ++ GG +V    D Y  S +++LF++ C+ IA  W YG+++F KD   MLGF    +W+ CW   SP+    + I +V   S++ ++     +  W+  +G FL L SV+ IP +   Y
Sbjct:  100 RDKWATKMEFLLAVVGYAVDLGNIWRFPSVCYKHGGGAFLIPYFIMLMIGGLPMFYMELVLGQFHRSGCVSIWRKVCPLFRGIGYGICCICTFIAIFYNAIIAQAVYFAIVSLSKIWDSEVPWASCGNPWNTPRCSDDLNVTI----SRNG-----------------TPLTTPSEEYYLYKVLEVQKSTGFDDLGGVKTSMAVCLLAVFIMVYFALWKGPQSSGKIVWVTATAPYIILSILLIRGLLLPGAKNGLYYYVTPDFEKLKDPAVWSAAATQIFFSLGPGFGVLLALSSYNDFNNNCYRDAVTTSIINCATSFFSGCVVFSTLGYMSLLTNKPINEVVGEHDASLIFIVYPQALATMDYSCFWSFIFFVMLITLGIDSTFAGIEAFITGFCDE-SRFLSKNRKWFVLVICIIYYFLSFPAISYGGQFVIPFLDEYGVS-LSVLFIVTCEMIAVCWFYGVDQFSKDIRAMLGFYPGIYWRVCWTC-SPVFISVIFIMTVYNSSFKPIQMASYTFPWWSVILGWFLRLLSVLAIPVFAIIY 621          
BLAST of slc6a-1 vs. Ensembl Celegans
Match: snf-5 (Sodium-dependent transporter snf-5 [Source:UniProtKB/Swiss-Prot;Acc:G5EBM5])

HSP 1 Score: 254.218 bits (648), Expect = 2.064e-74
Identity = 189/565 (33.45%), Postives = 299/565 (52.92%), Query Frame = 3
Query:  180 TSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCL-VFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWN--TQCCNSDN-----NVTALCNNSD--NGILDSKMKM-NFSHLCTECKAWN--SPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYL-KPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKW--------WKFC--WLIFSPLVCMFVLIFS-VLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIP 1799
            T  E  +  R+ + +  +FVL+++GL VGLGNIWRFP   Y NGG AFLIPYL      G+P +  E + GQ +      +++    + +GVG+  V +A  ++IYYIVI+++  +YM N    +   WS CN+ WN  T C    +     N T +  NS   N  L    KM  F+  C +    +  +   +++  +++  SSG+   G   W +  A+   W+L    I KG K  GKI Y + L PYVL++ LFI G+   GS  G++ Y   PN +KL E   W +   Q+ FS  +G G  I+L SY+  +NN  RDALI+ + + + SL  G  VF+ +G++A    ++VKDVVKSG  L F+VYP A+ ++P    W  +FFLM+  LG  ++   ++ F + I D++P +FR  + +++   C V Y IGL   T+ G Y F +FD Y A+G + +  + C+ +   + YG      D  +++G + +K+        W F   W++ SP + + ++  S V  Y ++   D  Y       G FL+   VI++P
Sbjct:   73 TPPEEEEEKRDGFGNSFEFVLTSLGLAVGLGNIWRFPTRAYNNGGSAFLIPYLTCAFLFGLPAVYFEFLTGQYQGKSPPVIFRRVRPILEGVGWMGVFVAALVAIYYIVIVSWISIYMINICRGHFALWSHCNNDWNNGTSCITMADQYLCKNHTKVMANSTLWNSSLPIPDKMVYFNGACQDANGTDVSTATEQYFMTYIVQPSSGMLDFGGFNWPVFAAMSVCWLLTGLGILKGAKIMGKISYVSVLVPYVLVVVLFINGVFQDGSGVGLEMYFGTPNYTKLYEQDTWTEALKQLCFSLSVGHGGLISLSSYSPKRNNIFRDALIVIIGDTTMSLVGGGAVFATLGYLAKATGQDVKDVVKSGLSLAFVVYPEAMTRMPVPWLWCFIFFLMLFLLGASTEIALVDVFCSCIYDQYP-RFRNRKWIVVIAWCSVLYCIGLVFSTRAGYYWFEMFDEY-AAGFSSVCTVVCELLVMMYIYGFRNVRDDITEVVGHARNKFTGAIGAHSWYFTANWMVISPSIALILVGLSFVREYPYMGRHDI-YPAVFDIFGWFLSFLPVIIVP 634          
BLAST of slc6a-1 vs. Ensembl Fly
Match: Gat (gene:FBgn0039915 transcript:FBtr0089972)

HSP 1 Score: 602.823 bits (1553), Expect = 0.000e+0
Identity = 314/609 (51.56%), Postives = 426/609 (69.95%), Query Frame = 3
Query:  102 NRDLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKM-NFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENI 1925
            +++L     ++SS  ++      + L   E   + R  WSSK+DF+LS +GL +GLGN+WRFPYLCY+NGGGAF++PY++TL  AG+P+  +EL +GQM +IGGLGV+K   +FKG+GYAA +M+ W+++YYIVILA+A  Y F S   + +PW  CN+ WNT  C S      L +  D  I  +  K+ + S L         PV EFWER  L  S GIE  G+I+W+LA  LL  WILCYFCIWKGVKWTGK+VYFTALFPYVLL  L +RG+TL G+ EGIKFY+ PN SKL  S+VW+D  TQIFFSYGLGLGT +ALGSYNK+ NN ++DALI+  VN+STS+FAGFV+FSV+GFMAH+Q + V DV  SG GL FLVYPSA+ QLPGS  WS LFF M++ +GLDSQFCT+EGF+TAIIDEWP   R+ +++ + +VC +SYL+GL+ +TQGG Y+F++ D Y+ SG  LL+LIF +C++ SWCYG++RF      M+G+  + WWKFCW + +P +C+ V  F+++ +  VKY D  Y  WAHA G F ALSS++ IP Y+F+      +  +    + E +R + +  +ED+T  +E +
Sbjct:   24 SKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPD-RGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRAD-VPWRTCNNWWNTVNCVSQYERKNL-HCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFW------LWKRTPGELSEKIRALVR-IDEDVTRLREKM 622          
BLAST of slc6a-1 vs. Ensembl Fly
Match: Gat (gene:FBgn0039915 transcript:FBtr0089971)

HSP 1 Score: 484.567 bits (1246), Expect = 2.399e-165
Identity = 257/465 (55.27%), Postives = 336/465 (72.26%), Query Frame = 3
Query:  102 NRDLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKM-NFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVF 1493
            +++L     ++SS  ++      + L   E   + R  WSSK+DF+LS +GL +GLGN+WRFPYLCY+NGGGAF++PY++TL  AG+P+  +EL +GQM +IGGLGV+K   +FKG+GYAA +M+ W+++YYIVILA+A  Y F S   + +PW  CN+ WNT  C S      L +  D  I  +  K+ + S L         PV EFWER  L  S GIE  G+I+W+LA  LL  WILCYFCIWKGVKWTGK+VYFTALFPYVLL  L +RG+TL G+ EGIKFY+ PN SKL  S+VW+D  TQIFFSYGLGLGT +ALGSYNK+ NN ++DALI+  VN+STS+FAGFV+FSV+GFMAH+Q + V DV  SG GL FLVYPSA+ QLPGS  WS LFF M++ +GLDSQFCT+EGF+TAIIDEWP   R+ +++ + +VC +SYL+GL+ +TQ  A+ +
Sbjct:   24 SKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPD-RGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRAD-VPWRTCNNWWNTVNCVSQYERKNL-HCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQLAAFAY 485          
BLAST of slc6a-1 vs. Ensembl Fly
Match: DAT (gene:FBgn0034136 transcript:FBtr0330002)

HSP 1 Score: 469.929 bits (1208), Expect = 8.289e-158
Identity = 252/589 (42.78%), Postives = 374/589 (63.50%), Query Frame = 3
Query:  150 SKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCN-----SDNNVTALCNNSD------NGILDSKMKMNFSHLCTEC----KAWNSPVLEFWERFVL--GESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL 1862
            SKS+             + RE WS KVDF+LS IG  V L N+WRFPYLCY+NGGGAFL+PY + LV  G+P+  +EL +GQ    G +  W +   +FKG+GYA V++AF++  YY VI+A++  + F SFT N LPW+ CN+ WNT  C      + + V  + N SD        +L ++  MN S L T      + + S   E++ R++L    S GI   G+I+W +AL LL  +++CYF +WKG+  +GK+V+FTALFPY +LL L IRG+TL GS  GI++YL PN S + +++VW+D ATQ+FFS G G G  +A  SYNKY NN ++DAL+   +N++TS  AGFV+FSV+G+MAH     ++DV   G GL+F+VYP+A+A +P S FW+++FF+M++ LGLDS F   E  +TA+ DE+P K +++R+L +  +  + +++GL+  TQGG Y F L D Y A+G ++L  +F + IA SW YG NRF +D   M+GF   ++W+ CW   +P+  +F+ ++ ++ YE + Y D  Y +WA+A+G  +A SSV+MIP    +       S +   +IL
Sbjct:    8 SKSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFT-NSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFP-KIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRY-AAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTIL 593          
BLAST of slc6a-1 vs. Ensembl Fly
Match: DAT (gene:FBgn0034136 transcript:FBtr0087125)

HSP 1 Score: 469.159 bits (1206), Expect = 9.782e-158
Identity = 252/589 (42.78%), Postives = 374/589 (63.50%), Query Frame = 3
Query:  150 SKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCN-----SDNNVTALCNNSD------NGILDSKMKMNFSHLCTEC----KAWNSPVLEFWERFVL--GESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL 1862
            SKS+             + RE WS KVDF+LS IG  V L N+WRFPYLCY+NGGGAFL+PY + LV  G+P+  +EL +GQ    G +  W +   +FKG+GYA V++AF++  YY VI+A++  + F SFT N LPW+ CN+ WNT  C      + + V  + N SD        +L ++  MN S L T      + + S   E++ R++L    S GI   G+I+W +AL LL  +++CYF +WKG+  +GK+V+FTALFPY +LL L IRG+TL GS  GI++YL PN S + +++VW+D ATQ+FFS G G G  +A  SYNKY NN ++DAL+   +N++TS  AGFV+FSV+G+MAH     ++DV   G GL+F+VYP+A+A +P S FW+++FF+M++ LGLDS F   E  +TA+ DE+P K +++R+L +  +  + +++GL+  TQGG Y F L D Y A+G ++L  +F + IA SW YG NRF +D   M+GF   ++W+ CW   +P+  +F+ ++ ++ YE + Y D  Y +WA+A+G  +A SSV+MIP    +       S +   +IL
Sbjct:    8 SKSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFT-NSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFP-KIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRY-AAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTIL 593          
BLAST of slc6a-1 vs. Ensembl Fly
Match: SerT (gene:FBgn0010414 transcript:FBtr0072362)

HSP 1 Score: 439.113 bits (1128), Expect = 4.495e-146
Identity = 248/609 (40.72%), Postives = 363/609 (59.61%), Query Frame = 3
Query:   99 NNRDLSSAKQMESSIASSKSQLGDKTLTSTEG------TDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKY-CLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLG--ESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNE 1898
            NN D S+    + +  +  +      L + E       T+  RE W  K +F+L+ IG  V LGN+WRFPY+CY+NGGGAFL+PY L L+F G+P+  +EL +GQ    G L +WK  C   KGVGYA  ++  ++ +YY  I+ +A  Y+F SFT + LPW+ C++PWNT+ C     VT+                NF+ L T      SP  EF+ER VL   + +G++  G ++  LAL +   ++L YF +WKGV+  GK+V+ TAL PYV+L+ L +RG++L G+ EGIK+YL P   KLK SKVW+D A+QIFFS G G GT +AL SYNK+ NNC+RDALI   +N  TS  AGFV+FSV+G+MA+ Q   +  V   G GL+F+VYP A+A + GS FWSI+FFLM+I LGLDS F  LE  +TA+ DE+P    + R+L + ++    +L  L  +T GG  +    + Y   G+A+LF++F +     W YG++RF  D  +MLG     +W+ CW   SP+  + + IFS++ Y+ +  ++  Y  W++ +G  +  SSV+ IP YI Y  F       ++    + L++ FQP + 
Sbjct:   32 NNEDDSNEDDGDHTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFT-SKLPWTSCDNPWNTENCM---QVTS---------------ENFTELAT------SPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVY-GPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFF-----FASKGGCRQRLQESFQPEDN 609          
BLAST of slc6a-1 vs. Ensembl Zebrafish
Match: slc6a1a (solute carrier family 6 member 1a [Source:ZFIN;Acc:ZDB-GENE-060519-23])

HSP 1 Score: 582.022 bits (1499), Expect = 0.000e+0
Identity = 298/608 (49.01%), Postives = 403/608 (66.28%), Query Frame = 3
Query:   99 NNRDLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKEN 1922
             + D     ++     + K +  D      +     RE W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+  LE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+A+A  Y++NSFT + LPW  CN+PWNT  C ++ ++    N +                        S V+EFWER V   + G+E PG I+  LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY +L  LFIRG+TL G+ EGI FY+ P+  KLKES+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFM+H   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R+ R++ +  VC VSY IGLS +TQGG YVF+LFD+YSASGM LLFL+F +CI+ SWCYG+N+F  +  +M+G+    WWK CW+ F+PLV   V +FS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       ++K      E +R + QP    +   +EN
Sbjct:    7 KSTDGQVVTELNEITTNDKPKTEDAKPEKNKKDIPDRETWGGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLECALGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIIAWALYYLYNSFTTD-LPWKSCNNPWNTDRCYTNYSIVDTTNLT------------------------SAVMEFWERNVHQMTDGLEKPGEIRVPLAITLAIAWVLVYFCIWKGVSWTGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYITPDFEKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYRDSIIVCCINSFTSMFAGFVIFSIVGFMSHVTKRPIADVAASGPGLAFLAYPEAVTQLPVSPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEFPRLLRKRREIFIACVCVVSYAIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECISISWCYGVNKFYDNIQEMIGYKPCIWWKLCWVFFTPLVVAGVFLFSAVQMVPLTMNNYVFPKWGQGVGWLMALSSMVLIPGYMGYMFLNLKGTYK------ERIRIMLQP--PAVKRAQEN 581          
BLAST of slc6a-1 vs. Ensembl Zebrafish
Match: slc6a1b (solute carrier family 6 member 1b [Source:ZFIN;Acc:ZDB-GENE-041114-57])

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 302/605 (49.92%), Postives = 408/605 (67.44%), Query Frame = 3
Query:  132 ESSIASSKSQ-LGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIRN 1943
            E+  A+ K + L  K     E  D  RE W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+  LE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+A+A  Y++NSFT + LPW  C++PWNT  C S+ ++  + N +                        S V+EFWER +   + G+E PG I+  LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY +L  LFIRG+TL G+ EGI FY+ P  SKLKES+VWLD ATQIFFSYGLGLG+ IALGSYN + NN ++D++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W++LFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R++ + VVC VSYLIGLS +TQGG YVF+LFD+YSASGM LLFL+F +C++ SW YG+N+F  +  +M+G+    WWK CW++F+PL+   V +FS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       S+K      E LR + QPT   +  ++   +    N
Sbjct:   19 EAPTANDKPKTLVVKVQKKKELPD--RETWQGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLETALGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIIAWAIYYLYNSFTTD-LPWKSCDNPWNTDKCFSNYSMANIGNMT------------------------SAVVEFWERNMHQLTDGLEKPGEIRLPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYVTPEFSKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYKDSIIVCCINSFTSMFAGFVIFSIVGFMAHITKRPIADVAASGPGLAFLAYPEAVTQLPISPLWAVLFFSMLLMLGIDSQFCTVEGFITALVDEFPRALRGRREIFIAVVCLVSYLIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECVSISWFYGVNKFYGNLEEMIGYKPCIWWKLCWVVFTPLIVAGVFLFSAVQMVPLTLNNYVFPKWGQGVGWCMALSSMVLIPGYMGYMFLTLKGSYK------ERLRIMIQPTAAAVRTQENGPEQQPEN 590          
BLAST of slc6a-1 vs. Ensembl Zebrafish
Match: slc6a1l (solute carrier family 6 member 1, like [Source:ZFIN;Acc:ZDB-GENE-041210-296])

HSP 1 Score: 525.013 bits (1351), Expect = 4.293e-180
Identity = 280/600 (46.67%), Postives = 391/600 (65.17%), Query Frame = 3
Query:  129 MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIIS-----HKNEKSILEILRDVFQPTNEDITDK 1913
            M+ +I           +   E     R  W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY  TLVFAG+P+ LLE  +GQ  S+GGLGVWK   + KGVG AAV+++FWL+IYYI+I+A+A  Y+F+S     LPW  C++PWNT  C S+ ++    N S                        S V EFWER +   ++G+E PG ++W L   L  +WIL YF IWKGV+WTGK+VYF+A +PY +L  LF RG+TL G+ +G+ FY+ PN +KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAG V+FS++GFM++   + ++++  SG GL FL YP A+ QLP S+ W+ILFF M++ LGLDSQFCT+EGF+TA++DE+P   R+ +K+ + +VC VS++IG S +TQGG YVF+LFD+YSASGM LLFL+F + I+ +W YG  +F K+  +M+G+    +WK CW+ F+P +C+ V  FS +    +      Y  W   +G  ++LSS+++IPGYI Y  F    +     HK  K       DV   T+  I D+
Sbjct:    1 MKQAIPFEDLDHNSIPVEEKENKIPDRGSWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFTTLVFAGIPLFLLETALGQYTSVGGLGVWKLIPMMKGVGLAAVVLSFWLNIYYIIIIAWALYYLFSSLKAE-LPWQTCDNPWNTDRCFSNYSLLDTTNLS------------------------SAVTEFWERNMHQLTNGLEEPGELRWPLVGTLALSWILVYFSIWKGVEWTGKVVYFSATYPYFMLFILFFRGVTLPGAIDGVLFYITPNFNKLLKSEVWLDAATQIFFSYGLGLGSLIALGSYNSFNNNVYRDSVIVCCINSCTSMFAGIVIFSIVGFMSYITKRPIEELAASGPGLAFLAYPQAVTQLPMSSLWAILFFSMLMMLGLDSQFCTVEGFITALMDEYPTVLRKRKKIFILIVCLVSFIIGFSNITQGGLYVFKLFDYYSASGMCLLFLVFFETISIAWFYGAEKFYKNIEEMIGYRPCGFWKQCWIYFTPTICLGVFTFSAIEMTPLTLGKYVYPAWGQGVGWLMSLSSMVLIPGYIIYMFFSTKGNIRQRWHKMTKPTELTTSDVNDLTHTGIMDE 575          
BLAST of slc6a-1 vs. Ensembl Zebrafish
Match: slc6a1l (solute carrier family 6 member 1, like [Source:ZFIN;Acc:ZDB-GENE-041210-296])

HSP 1 Score: 517.309 bits (1331), Expect = 2.276e-177
Identity = 272/568 (47.89%), Postives = 380/568 (66.90%), Query Frame = 3
Query:  129 MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQ--GLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQ 1826
            M+ +I           +   E     R  W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY  TLVFAG+P+ LLE  +GQ  S+GGLGVWK   + KGVG AAV+++FWL+IYYI+I+A+A  Y+F+S     LPW  C++PWNT  C S+ ++    N S                        S V EFWER +   ++G+E PG ++W L   L  +WIL YF IWKGV+WTGK+VYF+A +PY +L  LF RG+TL G+ +G+ FY+ PN +KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAG V+FS++GFM++   + ++++  SG   GL FL YP A+ QLP S+ W+ILFF M++ LGLDSQFCT+EGF+TA++DE+P   R+ +K+ + +VC VS++IG S +TQGG YVF+LFD+YSASGM LLFL+F + I+ +W YG  +F K+  +M+G+    +WK CW+ F+P +C+ V  FS +    +      Y  W   +G  ++LSS+++IPGYI Y  F 
Sbjct:    1 MKQAIPFEDLDHNSIPVEEKENKIPDRGSWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFTTLVFAGIPLFLLETALGQYTSVGGLGVWKLIPMMKGVGLAAVVLSFWLNIYYIIIIAWALYYLFSSLKAE-LPWQTCDNPWNTDRCFSNYSLLDTTNLS------------------------SAVTEFWERNMHQLTNGLEEPGELRWPLVGTLALSWILVYFSIWKGVEWTGKVVYFSATYPYFMLFILFFRGVTLPGAIDGVLFYITPNFNKLLKSEVWLDAATQIFFSYGLGLGSLIALGSYNSFNNNVYRDSVIVCCINSCTSMFAGIVIFSIVGFMSYITKRPIEELAASGHCPGLAFLAYPQAVTQLPMSSLWAILFFSMLMMLGLDSQFCTVEGFITALMDEYPTVLRKRKKIFILIVCLVSFIIGFSNITQGGLYVFKLFDYYSASGMCLLFLVFFETISIAWFYGAEKFYKNIEEMIGYRPCGFWKQCWIYFTPTICLGVFTFSAIEMTPLTLGKYVYPAWGQGVGWLMSLSSMVLIPGYIIYMFFS 543          
BLAST of slc6a-1 vs. Ensembl Zebrafish
Match: slc6a8 (solute carrier family 6 member 8 [Source:ZFIN;Acc:ZDB-GENE-071024-2])

HSP 1 Score: 503.827 bits (1296), Expect = 5.357e-171
Identity = 256/540 (47.41%), Postives = 371/540 (68.70%), Query Frame = 3
Query:  204 HREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKF--RQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKD-KEYATWAHAIGIFLALSSVIMIPGYIFY 1814
             RE W+ ++DF++S +G  VGLGN+WRFPYLCY+NGGG FLIPY+L +   G+PI  LE+ +GQ    G + VW    +FKG+GYA++++ F+ + YYI++LA+ F Y   SF    LPWS C++PWNT+ C           +  NG + +    N +  C E     SP++EFWE  VL  S G++ PG++ W+L L LL  W++ YFC+WKGVK TGKIVYFTA FPYV+L+ L +RG+TL G+ +GI +Y+KP+ SKL E++VW+D  TQIFFSY +GLG   ALGSYN++ N+C++DA ++ ++N+ TS FAGFVVFS++GFMA +Q  ++  V +SG GL F+ YP A++ +P +  W+ LFF+M++ LGLDSQF  +EGF+T I+D +P K+  R  R++ + + C + ++I LSMVTQGG YVF+LFD+YSASGM LL+  F +C+  +W YG +RF+ D  +M+G+    W K+CW I +P VCM + +F +L+Y+ + Y +   Y  W   IG  LALSS++ IP  + Y
Sbjct:   45 ERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLFIFLGGIPIFFLEIALGQFMKAGSINVWNIAPLFKGLGYASMVIVFFCNTYYIMVLAWGFYYFIKSFNAT-LPWSTCDNPWNTENCIE----IFRQGDCKNGTIGNSTFGNLT--CEELANGRSPIIEFWENKVLNISDGLDEPGAVNWELMLCLLAVWVMVYFCVWKGVKSTGKIVYFTATFPYVVLIILLVRGVTLPGAYDGILYYVKPDWSKLGEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFVLALINSGTSFFAGFVVFSILGFMASEQGVDISKVAESGPGLAFIAYPKAVSMMPVAPVWAALFFIMLLLLGLDSQFVGVEGFVTGILDLFPGKYYMRYQREIAVAICCLLCFIIDLSMVTQGGMYVFQLFDYYSASGMTLLWQAFWECVVVAWVYGADRFMDDIARMIGYRPFPWMKWCWSIITPCVCMGIFLFHLLNYKPLTYNNVYVYPWWGEVIGWCLALSSMLCIPVSLVY 577          
BLAST of slc6a-1 vs. Ensembl Xenopus
Match: slc6a13 (solute carrier family 6 (neurotransmitter transporter), member 13 [Source:NCBI gene;Acc:780375])

HSP 1 Score: 561.607 bits (1446), Expect = 0.000e+0
Identity = 287/582 (49.31%), Postives = 398/582 (68.38%), Query Frame = 3
Query:  195 TDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIR 1940
             D+ R  W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTLVFAG+P+  LE  +GQ  SIGGLGVWK   +FKGVG AAV+++FWL+IYYIVI+A+A  Y+FNSF+ + LPW  C++ WNT+ C S+ ++    N++ N                      S V EFWER +   + G+  PG+I+W LA  L  AWI+ YF IWKGV+WTGK+VYF+A +PY +L+ LF RG+TL G+ +GI+FY+ P+ SKL  S+VW+D ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N++TS+FAGFV+FS++GFM+H   K ++++  SG GL FL YP A+ QLP S  WSILFF M++ LGLDSQFCT+EGF+TA++DE+P   R  +K+ + +VC +S++IG S +TQGG YVF+LFD+YSASGM LLFL+F + ++ SWCYG++RF +D  +M+G+    WWK CW  F+P +C+ V  FSV     +      Y  W   IG  +ALSS++ IPGY+ Y            K  L  +R +     + +    ++I++++R
Sbjct:   37 ADDDRGTWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLVFAGIPLFFLETALGQFTSIGGLGVWKLAPMFKGVGMAAVVLSFWLNIYYIVIIAWALYYLFNSFS-STLPWQSCDNSWNTERCFSNYSL----NDTSN--------------------LTSAVTEFWERNMHQMTGGLGEPGNIRWPLACTLALAWIMVYFSIWKGVEWTGKVVYFSATYPYFMLVILFFRGITLPGAMDGIRFYITPDFSKLANSEVWMDAATQIFFSYGLGLGSLIALGSYNAFDNNIYRDSIIVCGINSTTSMFAGFVIFSIVGFMSHITKKPIQELAASGPGLAFLAYPQAVTQLPMSPVWSILFFSMLVMLGLDSQFCTVEGFITALVDEYPQCLRSRKKVFIAMVCFISFIIGFSNITQGGLYVFKLFDYYSASGMCLLFLVFFETVSISWCYGVDRFYQDIEEMIGYQPCSWWKLCWAYFTPCICLGVFCFSVFEMTPLTLGRYVYPAWGQGIGWLMALSSMVFIPGYMLYLLL-------TTKGTLRQVRTLVHQWLQRMRLLYKDIKILLR 586          
BLAST of slc6a-1 vs. Ensembl Xenopus
Match: slc6a13 (solute carrier family 6 (neurotransmitter transporter), member 13 [Source:NCBI gene;Acc:780375])

HSP 1 Score: 561.607 bits (1446), Expect = 0.000e+0
Identity = 287/582 (49.31%), Postives = 398/582 (68.38%), Query Frame = 3
Query:  195 TDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIR 1940
             D+ R  W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTLVFAG+P+  LE  +GQ  SIGGLGVWK   +FKGVG AAV+++FWL+IYYIVI+A+A  Y+FNSF+ + LPW  C++ WNT+ C S+ ++    N++ N                      S V EFWER +   + G+  PG+I+W LA  L  AWI+ YF IWKGV+WTGK+VYF+A +PY +L+ LF RG+TL G+ +GI+FY+ P+ SKL  S+VW+D ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N++TS+FAGFV+FS++GFM+H   K ++++  SG GL FL YP A+ QLP S  WSILFF M++ LGLDSQFCT+EGF+TA++DE+P   R  +K+ + +VC +S++IG S +TQGG YVF+LFD+YSASGM LLFL+F + ++ SWCYG++RF +D  +M+G+    WWK CW  F+P +C+ V  FSV     +      Y  W   IG  +ALSS++ IPGY+ Y            K  L  +R +     + +    ++I++++R
Sbjct:   39 ADDDRGTWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLVFAGIPLFFLETALGQFTSIGGLGVWKLAPMFKGVGMAAVVLSFWLNIYYIVIIAWALYYLFNSFS-STLPWQSCDNSWNTERCFSNYSL----NDTSN--------------------LTSAVTEFWERNMHQMTGGLGEPGNIRWPLACTLALAWIMVYFSIWKGVEWTGKVVYFSATYPYFMLVILFFRGITLPGAMDGIRFYITPDFSKLANSEVWMDAATQIFFSYGLGLGSLIALGSYNAFDNNIYRDSIIVCGINSTTSMFAGFVIFSIVGFMSHITKKPIQELAASGPGLAFLAYPQAVTQLPMSPVWSILFFSMLVMLGLDSQFCTVEGFITALVDEYPQCLRSRKKVFIAMVCFISFIIGFSNITQGGLYVFKLFDYYSASGMCLLFLVFFETVSISWCYGVDRFYQDIEEMIGYQPCSWWKLCWAYFTPCICLGVFCFSVFEMTPLTLGRYVYPAWGQGIGWLMALSSMVFIPGYMLYLLL-------TTKGTLRQVRTLVHQWLQRMRLLYKDIKILLR 588          
BLAST of slc6a-1 vs. Ensembl Xenopus
Match: slc6a13 (solute carrier family 6 (neurotransmitter transporter), member 13 [Source:NCBI gene;Acc:780375])

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 292/594 (49.16%), Postives = 404/594 (68.01%), Query Frame = 3
Query:  159 QLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIR 1940
            QLG +    TE T +   Q S K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTLVFAG+P+  LE  +GQ  SIGGLGVWK   +FKGVG AAV+++FWL+IYYIVI+A+A  Y+FNSF+ + LPW  C++ WNT+ C S+ ++    N++ N                      S V EFWER +   + G+  PG+I+W LA  L  AWI+ YF IWKGV+WTGK+VYF+A +PY +L+ LF RG+TL G+ +GI+FY+ P+ SKL  S+VW+D ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N++TS+FAGFV+FS++GFM+H   K ++++  SG GL FL YP A+ QLP S  WSILFF M++ LGLDSQFCT+EGF+TA++DE+P   R  +K+ + +VC +S++IG S +TQGG YVF+LFD+YSASGM LLFL+F + ++ SWCYG++RF +D  +M+G+    WWK CW  F+P +C+ V  FSV     +      Y  W   IG  +ALSS++ IPGY+ Y            K  L  +R +     + +    ++I++++R
Sbjct:    1 QLG-QPFPITE-TSHTLYQLSWKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLVFAGIPLFFLETALGQFTSIGGLGVWKLAPMFKGVGMAAVVLSFWLNIYYIVIIAWALYYLFNSFS-STLPWQSCDNSWNTERCFSNYSL----NDTSN--------------------LTSAVTEFWERNMHQMTGGLGEPGNIRWPLACTLALAWIMVYFSIWKGVEWTGKVVYFSATYPYFMLVILFFRGITLPGAMDGIRFYITPDFSKLANSEVWMDAATQIFFSYGLGLGSLIALGSYNAFDNNIYRDSIIVCGINSTTSMFAGFVIFSIVGFMSHITKKPIQELAASGPGLAFLAYPQAVTQLPMSPVWSILFFSMLVMLGLDSQFCTVEGFITALVDEYPQCLRSRKKVFIAMVCFISFIIGFSNITQGGLYVFKLFDYYSASGMCLLFLVFFETVSISWCYGVDRFYQDIEEMIGYQPCSWWKLCWAYFTPCICLGVFCFSVFEMTPLTLGRYVYPAWGQGIGWLMALSSMVFIPGYMLYLLL-------TTKGTLRQVRTLVHQWLQRMRLLYKDIKILLR 560          
BLAST of slc6a-1 vs. Ensembl Xenopus
Match: slc6a13 (solute carrier family 6 (neurotransmitter transporter), member 13 [Source:NCBI gene;Acc:780375])

HSP 1 Score: 548.125 bits (1411), Expect = 0.000e+0
Identity = 287/577 (49.74%), Postives = 393/577 (68.11%), Query Frame = 3
Query:  204 HREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCC------NSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDK 1913
             R QW++KV+FVLS  G  +GLGN+WRFPYLCY+NGGGAF IPYL+ L   G+P+  LE  +GQ  S GG+  W K C +F+G+GY++ ++   L+ YYIV+LA+A  Y+FNSFT + LPW+ C H WNT+ C      NS +NVT       NG                     S V+EFWER VL  S GI+  G + W+LAL LL AWI+CYFCIWKGVK TGK+VYFTA FPY++L+ L IRG++L G+  GI+FYL P++S+L++ +VW+D ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N++TS+FAGFV+FS++GFM+H   K ++++  SG GL FL YP A+ QLP S  WSILFF M++ LGLDSQFCT+EGF+TA++DE+P   R  +K+ + +VC +S++IG S +TQGG YVF+LFD+YSASGM LLFL+F + ++ SWCYG++RF +D  +M+G+    WWK CW  F+P +C+ V  FSV     +      Y  W   IG  +ALSS++ IPGY+ Y           + ++ +  R++ QP  E I  K
Sbjct:   36 ERGQWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTSQGGVTAWRKICPLFEGIGYSSQVIVMLLNCYYIVVLAWALFYLFNSFT-SELPWASCGHSWNTENCLDFYKGNSTHNVTL------NG--------------------TSSVIEFWERRVLRISDGIDNIGGLHWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIVLLIRGVSLPGALTGIQFYLYPDLSRLQDPQVWMDAATQIFFSYGLGLGSLIALGSYNAFDNNIYRDSIIVCGINSTTSMFAGFVIFSIVGFMSHITKKPIQELAASGPGLAFLAYPQAVTQLPMSPVWSILFFSMLVMLGLDSQFCTVEGFITALVDEYPQCLRSRKKVFIAMVCFISFIIGFSNITQGGLYVFKLFDYYSASGMCLLFLVFFETVSISWCYGVDRFYQDIEEMIGYQPCSWWKLCWAYFTPCICLGVFCFSVFEMTPLTLGRYVYPAWGQGIGWLMALSSMVFIPGYMLYLLL------TTKGTLRQRFREMTQPKMEQIMQK 579          
BLAST of slc6a-1 vs. Ensembl Xenopus
Match: slc6a8l (solute carrier family 6 (neurotransmitter transporter), member 8 like [Source:NCBI gene;Acc:100127575])

HSP 1 Score: 506.138 bits (1302), Expect = 1.774e-171
Identity = 259/535 (48.41%), Postives = 364/535 (68.04%), Query Frame = 3
Query:  204 HREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIP 1799
             RE W+ ++DF++S +G  VGLGN+WRFPYLCY+NGGG FLIPYLL +   G+P+  LE+ +GQ    GG+  W    +FKG+G+A++++ F+ + YYI+IL +   Y+ +SFT N LPW+ C +PWN++ C     V    N S   + DS   +N S  C       SPV+EFWER VL  S G+  PG + WQ+ L L+  W++ YFCIWKGVK TGK+VYFTALFPYV+L+ L   G+TL G+ +GI +YLKPN SKL E++VW+D  TQIFFSY +GLG   ALGSYN++ NNC+RDA I+  +N++TS FAGFVVFSV+GFMA +Q   +  V +SG GL F+ YP A+  +P +  W+ LFF M++ LGLDSQF  +EGF+T I+D +P        R++   + C V ++I LSMVT+GG YVF+LFD+YSASG+ LL+  F +C+  +W YG +RF+ D  +M+G+    + K+CW + +PLVC+ + +F V++Y+ + Y K   Y  W  AIG  LAL+S++ IP
Sbjct:   60 ERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLIVFVGGIPVFFLEIALGQFMKQGGIAAWNIAPLFKGLGFASMVIVFFCNTYYIMILVWGLYYLVHSFT-NTLPWATCGNPWNSKECTEVFLVDHCNNGSLANVTDSGTLVNIS--CDALVNKRSPVIEFWERKVLQISGGLNEPGQLNWQMILCLMATWVIVYFCIWKGVKSTGKVVYFTALFPYVVLIVLLAHGVTLPGALDGIVYYLKPNWSKLAEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFHNNCYRDAYILAAINSTTSFFAGFVVFSVLGFMASEQGVHISKVAESGPGLAFIAYPKAVTLMPFAPIWAALFFFMLLILGLDSQFVGVEGFITGIMDLFPQPINGFVRREVTAALCCLVCFIIDLSMVTEGGMYVFQLFDYYSASGITLLWQAFWECVVIAWVYGADRFMDDIARMIGYRPLPYMKWCWSVLTPLVCVGIFVFHVVNYKPLTYNKSYVYPWWGEAIGWSLALASMLCIP 591          
BLAST of slc6a-1 vs. Ensembl Mouse
Match: Slc6a1 (solute carrier family 6 (neurotransmitter transporter, GABA), member 1 [Source:MGI Symbol;Acc:MGI:95627])

HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0
Identity = 293/594 (49.33%), Postives = 401/594 (67.51%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNE-KSILEILRDVFQPTN 1895
            S +  E+ +AS K +     +    G    R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC VSYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V +FS +    +      +  W   +G  +ALSS+++IPGY+ Y       S K   + +++   D+ +P N
Sbjct:   14 STEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSLVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. Ensembl Mouse
Match: Slc6a6 (solute carrier family 6 (neurotransmitter transporter, taurine), member 6 [Source:MGI Symbol;Acc:MGI:98488])

HSP 1 Score: 498.434 bits (1282), Expect = 4.805e-169
Identity = 266/557 (47.76%), Postives = 376/557 (67.50%), Query Frame = 3
Query:  144 ASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKA-WNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIP 1799
             S     G +     +G    RE+WSSK+DFVLS  G  VGLGN+WRFPYLCY+NGGGAFLIPY + L  +G+P+  LE++IGQ  S GG+  W K C +F G+GYA++++   L++YYIVILA+A  Y+F+SF  + LPW+ CNH WNT  C  D                  ++ N SH  +   A + SPV+EFWER VL  SSGI+ PGS++W LAL LL  W++C+FCIWKGV+ TGK+VYFTA FP+ +LL L +RG+TL G+ EGIKFYL P+IS+L + +VW+D  TQIFFSY + LG   +LGSYNKYK N +RD +++G +N+ TS  +GF +FS++GFMA +Q  ++ DV +SG GL F+ YP A+  +P   FWSILFF+M++ LGLDSQF  +EG +T+++D +P   R+   R++ + ++C +SYL+GL+MVT+GG YVF+LFD+Y+ASG+ LL++ F +C   +W YG +        M+G+    W K+ W + +P +C+   +FS++ Y  + Y K   Y  WA  +G  LALSS++ IP
Sbjct:   20 PSPGKSPGTRPEDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFHSFQKD-LPWAHCNHSWNTPQCMEDT-----------------LRRNESHWVSLSTANFTSPVIEFWERNVLSLSSGIDNPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPDISRLGDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAILCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPALCVGCFVFSLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMLCIP 558          
BLAST of slc6a-1 vs. Ensembl Mouse
Match: Slc6a13 (solute carrier family 6 (neurotransmitter transporter, GABA), member 13 [Source:MGI Symbol;Acc:MGI:95629])

HSP 1 Score: 495.738 bits (1275), Expect = 3.309e-168
Identity = 269/582 (46.22%), Postives = 378/582 (64.95%), Query Frame = 3
Query:  204 HREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKY-CLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCC------NSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDK-EYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKE 1919
             RE W++K++FVLS  G  +GLGN+WRFPYLCY+NGGGAF IPYL+ L   G+P+  LE  +GQ  + GG+  W+  C +F+G+GYA+ ++   L++YYIV+LA+A  Y+F+SFT + LPW  C+H WNT+ C      N   NVT     S+N                      SPV+EFWER VL  S GI+  GS++W+L L LL AWI+CYFCIWKGVK TGK+VYFTA FPY++L+ L IRG+TL G+A+GI+FYL PNI++L + +VW+D  TQIFFS+ + LG   ALGSYNKY NNC+RD + + ++N+STS  AGF +FS++GFM+ +Q   + +V +SG GL F+ YP A+  LP S  W+  FF M++ LGLDSQF  +E  +TA++D +P  FR+   R++L+ +V  +S+ IGL M+T+GG YVF+LFD+Y+ASGM LLF+   + +  +W YG  RF  +   M+G+      K+CWL F+P VC+   +FS++ Y  + Y  K  Y  W  A+G  LALSS+I IP +  Y           +  + E LR +  P  ED+  K +
Sbjct:   31 EREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTD-LPWGSCSHEWNTENCVEFQKANDSMNVT-----SENA--------------------TSPVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMICIPAWSIYKL------RTLKGPLRERLRQLVCPA-EDLPQKNQ 579          
BLAST of slc6a-1 vs. Ensembl Mouse
Match: Slc6a8 (solute carrier family 6 (neurotransmitter transporter, creatine), member 8 [Source:MGI Symbol;Acc:MGI:2147834])

HSP 1 Score: 474.167 bits (1219), Expect = 2.045e-159
Identity = 255/539 (47.31%), Postives = 363/539 (67.35%), Query Frame = 3
Query:  207 REQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCC-----NSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWP--HKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKE-YATWAHAIGIFLALSSVIMIP 1799
            RE W+ ++DF++S +G  VGLGN+WRFPYLCY+NGGG FLIPY+L  +  G+PI  LE+ +GQ    G + VW  C +FKG+GYA++++ F+ + YYI++LA+ F Y+  SFT   LPW+ C H WNT  C     + D    +L N + + + D +                SPV+EFWE  VL  S+G+E PG++ W++ L LL  W+L YFC+WKGVK TGKIVYFTA FPYV+L+ L +RG+ L G+ +GI +YLKP+ SKL   +VW+D  TQIFFSY +GLG   ALGSYN++ NNC++DA+I+ ++N+ TS FAGFVVFS++GFMA +Q   +  V +SG GL F+ YP A+  +P +  W+ LFF M++ LGLDSQF  +EGF+T ++D  P  + FR  R++ + + C + ++I LSMVT GG YVF+LFD+YSASG  LL+  F +C+  +W YG +RF+ D   M+G+    W K+CW  F+PLVCM + IF+++ YE + Y +   Y  W  A+G   ALSS++ +P
Sbjct:   52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTT-LPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRR----------------SPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNIVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVP 573          
BLAST of slc6a-1 vs. Ensembl Mouse
Match: Slc6a8 (solute carrier family 6 (neurotransmitter transporter, creatine), member 8 [Source:MGI Symbol;Acc:MGI:2147834])

HSP 1 Score: 474.167 bits (1219), Expect = 2.045e-159
Identity = 255/539 (47.31%), Postives = 363/539 (67.35%), Query Frame = 3
Query:  207 REQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCC-----NSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWP--HKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKE-YATWAHAIGIFLALSSVIMIP 1799
            RE W+ ++DF++S +G  VGLGN+WRFPYLCY+NGGG FLIPY+L  +  G+PI  LE+ +GQ    G + VW  C +FKG+GYA++++ F+ + YYI++LA+ F Y+  SFT   LPW+ C H WNT  C     + D    +L N + + + D +                SPV+EFWE  VL  S+G+E PG++ W++ L LL  W+L YFC+WKGVK TGKIVYFTA FPYV+L+ L +RG+ L G+ +GI +YLKP+ SKL   +VW+D  TQIFFSY +GLG   ALGSYN++ NNC++DA+I+ ++N+ TS FAGFVVFS++GFMA +Q   +  V +SG GL F+ YP A+  +P +  W+ LFF M++ LGLDSQF  +EGF+T ++D  P  + FR  R++ + + C + ++I LSMVT GG YVF+LFD+YSASG  LL+  F +C+  +W YG +RF+ D   M+G+    W K+CW  F+PLVCM + IF+++ YE + Y +   Y  W  A+G   ALSS++ +P
Sbjct:   52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTT-LPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRR----------------SPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNIVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVP 573          
BLAST of slc6a-1 vs. UniProt/SwissProt
Match: sp|P23978|SC6A1_RAT (Sodium- and chloride-dependent GABA transporter 1 OS=Rattus norvegicus OX=10116 GN=Slc6a1 PE=1 SV=1)

HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0
Identity = 293/594 (49.33%), Postives = 401/594 (67.51%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNE-KSILEILRDVFQPTN 1895
            S +  E+ +AS K +     +    G    R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC VSYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V +FS +    +      +  W   +G  +ALSS+++IPGY+ Y       S K   + +++   D+ +P N
Sbjct:   14 STEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSLVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. UniProt/SwissProt
Match: sp|P31648|SC6A1_MOUSE (Sodium- and chloride-dependent GABA transporter 1 OS=Mus musculus OX=10090 GN=Slc6a1 PE=1 SV=2)

HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0
Identity = 293/594 (49.33%), Postives = 401/594 (67.51%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNE-KSILEILRDVFQPTN 1895
            S +  E+ +AS K +     +    G    R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC VSYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V +FS +    +      +  W   +G  +ALSS+++IPGY+ Y       S K   + +++   D+ +P N
Sbjct:   14 STEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSLVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. UniProt/SwissProt
Match: sp|P30531|SC6A1_HUMAN (Sodium- and chloride-dependent GABA transporter 1 OS=Homo sapiens OX=9606 GN=SLC6A1 PE=1 SV=2)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 292/594 (49.16%), Postives = 400/594 (67.34%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSIL-EILRDVFQPTN 1895
            S +  E+ +A+ K +     +         R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+W LA+ L  AWIL YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R+L +  VC +SYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V IFS +    +   +  +  W   +G  +ALSS+++IPGY+ Y       S K    ++ +   D+ +P N
Sbjct:   14 STEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSMVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPEN 582          
BLAST of slc6a-1 vs. UniProt/SwissProt
Match: sp|P48057|SC6A1_MUSCO (Sodium- and chloride-dependent GABA transporter 1 OS=Mus cookii OX=10098 GN=Slc6a1 PE=2 SV=1)

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 284/594 (47.81%), Postives = 392/594 (65.99%), Query Frame = 3
Query:  117 SAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNE-KSILEILRDVFQPTN 1895
            S +  E+ +AS K +     +    G    R+ W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVW    +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  C++PWNT  C S+ ++    N +                        S V+EFWER +   + G++ PG I+       +   +  YFCIWKGV WTGK+VYF+A +PY++L+ LF RG+TL G+ EGI FY+ PN  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+    R  R+L +  VC VSYLIGLS +TQGG YVF+LFD+YSASGM+LLFL+F +C++ SW YG+NRF  +  +M+G     WWK CW  F+P++   V +FS +    +      +  W   +G  +ALSS+++IPGY+ Y       S K   + +++   D+ +P N
Sbjct:   14 STEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWNVAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT-LPWKQCDNPWNTDRCFSNYSLVNTTNMT------------------------SAVVEFWERNMHQMTDGLDKPGQIRCLAITLAIAWVL-VYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYSRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPEN 581          
BLAST of slc6a-1 vs. UniProt/SwissProt
Match: sp|Q9MZ34|SC6A6_BOVIN (Sodium- and chloride-dependent taurine transporter OS=Bos taurus OX=9913 GN=SLC6A6 PE=2 SV=1)

HSP 1 Score: 503.442 bits (1295), Expect = 3.449e-170
Identity = 269/556 (48.38%), Postives = 374/556 (67.27%), Query Frame = 3
Query:  144 ASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIP 1799
             S     G +     EG    RE+W+S++DFVLS  G  VGLGN+WRFPYLCY+NGGGAFLIPY + L   G+P+  LE++IGQ  S GG+  W K C +F G+GYA++++   L+IYYI+ILA+A  Y+F SF  + LPW+ CNH WNT  C  D          +  +  S    NF+          SPV EFWER VL  SSGI+ PG+++W LAL LL  W++C+FCIWKGVK TGK+VYFTA FP+ +LL L +RG+TL G+  GIKFYL P+IS+L++ +VW+D  TQIFFSY + LG   +LGSYNKYK N +RD +++G +N+ TS  +GF +FS++GFMA +Q  ++ DV +SG GL F+ YP A+  +P   FWSILFF+M++ LGLDSQF  +EG +T+++D  P   R+  HR++ +  +C V+YL+GL+MVT+GG YVF+LFD+Y+ASG+ LL++ F +C A +W YG + F      M+G+    W K+CW + +PL+C    IFS++ Y  + Y K   Y TWA  +G  LALSS++ +P
Sbjct:   20 PSPGKSPGTRPEDEAEGKPPQREKWASRIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVIIGQYTSEGGITCWEKICPLFAGIGYASIVIVSLLNIYYIIILAWAMYYLFQSFQ-SELPWAKCNHSWNTPHCLEDTL------RRNRSLWISNSTANFT----------SPVTEFWERKVLSLSSGIDEPGALKWDLALCLLLVWLVCFFCIWKGVKSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLHPSLLRKGFHREIFIASICCVTYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFAIAWIYGSDNFYDGIEDMIGYRPGPWMKYCWAVVTPLLCTGCFIFSLVKYVPLTYNKVYTYPTWAIGLGWCLALSSMVCVP 558          
BLAST of slc6a-1 vs. TrEMBL
Match: A0A0H3YIU2 (Transporter OS=Schmidtea mediterranea OX=79327 GN=slc6a-1 PE=2 SV=1)

HSP 1 Score: 1184.47 bits (3063), Expect = 0.000e+0
Identity = 606/606 (100.00%), Postives = 606/606 (100.00%), Query Frame = 3
Query:  129 MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIRNV 1946
            MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSIQWQLALALLFAWILCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSILFFLMIIFLGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIRNV
Sbjct:    1 MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSIQWQLALALLFAWILCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSILFFLMIIFLGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIRNV 606          
BLAST of slc6a-1 vs. TrEMBL
Match: R7UHY8 (Transporter OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_220218 PE=3 SV=1)

HSP 1 Score: 631.328 bits (1627), Expect = 0.000e+0
Identity = 325/604 (53.81%), Postives = 427/604 (70.70%), Query Frame = 3
Query:   99 NNRDLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTEC---KAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNED 1901
              +D S+     S     KS+L D   +  +     RE WS K+DF+ S +G  +GLGN+WRFPYLCY NGGGAFLIPYLLTLV AG+P+ LLEL +GQ  SIGGLG+W+ C +FKGVGY+A I+AFWL+IYY+VILA+   Y+FNSFT   LPW+ C H WNT  C + +      N ++    D  + M  +  C+       + SPV EFWER  L  S G+  PG+++WQLAL LL AWI+CYFCIWKGVKWTGK+ +FTA+FPY+LL  L IRG+TL G+ EGIK+Y+ P+  +LK+SKVW++ ATQIFFSYGL LG  +ALGSYNKY NN +RDALII  VN++TS+FAGFV+FS +GFMA++Q + V +V  SG GL FLVYPSA+ QLP S  W+ILFF+M+ FLGLDSQFCT+EGF+TAI+DE+P   R+ ++L +  VC VSYLIGL+MVT+GG YVF+LFD YSASGM LLFLIF +C+A SW YG+NRF  + + M G+    WWK CW++F+P++C+ V +FSV+ ++ VKY D EY  W   IG  +A+SS+++ P Y  +Y F +      E+  L    D+ +P   +
Sbjct:    2 ETQDPSAKNGPSSETVPLKSELKDGDPSDDKDATPEREHWSGKMDFMFSCVGYSIGLGNVWRFPYLCYTNGGGAFLIPYLLTLVLAGIPMFLLELSLGQYLSIGGLGIWQICPIFKGVGYSAAIIAFWLNIYYVVILAWGLHYLFNSFTTE-LPWAKCGHWWNTDRCMTQDTRRQCSNFTEAA--DGMLNMTSNVSCSNALNYSIYTSPVKEFWERNTLQISGGLGEPGNVRWQLALTLLLAWIVCYFCIWKGVKWTGKVTWFTAVFPYILLFILLIRGVTLPGALEGIKYYIVPDFERLKDSKVWIEAATQIFFSYGLALGAQVALGSYNKYHNNVYRDALIISCVNSTTSIFAGFVIFSTIGFMANEQGRSVAEVADSGPGLAFLVYPSAVVQLPISPIWAILFFMMLFFLGLDSQFCTMEGFITAIVDEYPQYLRKRKELFVAAVCAVSYLIGLTMVTEGGMYVFQLFDKYSASGMCLLFLIFWECVAISWGYGVNRFYDNLHDMCGYYPGVWWKLCWVLFTPIICIGVFLFSVIKHKPVKYLDYEYPWWGELIGWVMAMSSILVTPIYGIWY-FSKTPGTFRERCKLCFRPDIDEPIKRN 601          
BLAST of slc6a-1 vs. TrEMBL
Match: A0A1S3JS62 (Transporter OS=Lingula unguis OX=7574 GN=LOC106175411 PE=3 SV=1)

HSP 1 Score: 629.402 bits (1622), Expect = 0.000e+0
Identity = 338/617 (54.78%), Postives = 434/617 (70.34%), Query Frame = 3
Query:  162 LGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSD----NNVTALCNNSDNGIL-----------------------DSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDI-TDKKENIQ 1928
            +GD T+   +     R  W+ K+DF++S +G  +GLGN+WRFPYLCY+NGGGAFL+PY LTL FAG+P+ LLE  IGQ  SIGGLGVWK C +FKGVGYAA ++AFWL+IYYIVILA+A  Y+ +SF    LPW+ C++ WNT+ C SD    N  TA  N  +  ++                        S +    + LC     + SPV EFWER  L  ++GI+ PG+I+WQL+L LLFAW LCYFCIWKGVKWTGK+VYFTALFPYVLLL L IRG+TL G+++GI FY+ P + KL +S+VW+D ATQIFFSYGLGLG  IALGSYN+Y NN ++DALI+  VN+ TS+FAGFV+FSV+GFMA QQ K V +V  SG GL FL YPSA+ QLP S  WS+LFF MI+FLGLDSQFCT+EGF+TA +DEWP   R+ +++ + VVC +SYLIGL+ +T+GG YVF+L D+YSASGM LLFLIFC+CIAFSW YG+NRF  D N M+G+    +WK+CWLIF+PL+C  VLIFS++ Y+  KY D EY  WA  IG F+ALSS++++P Y+ Y         ++   +L      F+P  + I  DK E + 
Sbjct:   41 MGDITV---DDDVPSRGNWTGKLDFIISCVGYAIGLGNVWRFPYLCYKNGGGAFLVPYFLTLFFAGIPMFLLESSIGQYLSIGGLGVWKLCPIFKGVGYAAAVVAFWLNIYYIVILAWALYYLVSSFQAV-LPWASCDNWWNTEWCRSDYVAPNCTTAFQNQLNETLVTINASLISSLGGTDDVTVYTSQNSSSINATTTALCQ--TNFTSPVREFWERNALRITNGIDEPGNIRWQLSLTLLFAWALCYFCIWKGVKWTGKVVYFTALFPYVLLLVLLIRGVTLPGASQGIWFYIYPKMEKLGDSQVWIDAATQIFFSYGLGLGAVIALGSYNRYHNNVYKDALIVCTVNSCTSMFAGFVIFSVVGFMAEQQQKPVSEVAASGPGLAFLAYPSAVVQLPISPLWSVLFFTMILFLGLDSQFCTMEGFITACVDEWPRVLRKRKEIFIAVVCLISYLIGLACITEGGMYVFQLMDYYSASGMCLLFLIFCECIAFSWAYGVNRFYDDINDMIGYYPCPFWKYCWLIFTPLICGGVLIFSIVQYKSPKYLDYEYPWWADMIGWFMALSSILVVPSYMIYRLASTPGDFRSRCKVL------FRPDIDSIRPDKGEPLS 645          
BLAST of slc6a-1 vs. TrEMBL
Match: A0A1S3JR41 (Transporter OS=Lingula unguis OX=7574 GN=LOC106175411 PE=3 SV=1)

HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0
Identity = 339/617 (54.94%), Postives = 435/617 (70.50%), Query Frame = 3
Query:  162 LGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSD----NNVTALCNNSDNGIL-----------------------DSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDI-TDKKENIQ 1928
            +GD T+   +     R  W+ K+DF++S +G  +GLGN+WRFPYLCY+NGGGAFL+PY LTL FAG+P+ LLE  IGQ  SIGGLGVWK C +FKGVGYAA ++AFWL+IYYIVILA+A  Y+ +SF    LPW+ C++ WNT+ C SD    N  TA  N  +  ++                        S +    + LC     + SPV EFWER  L  ++GI+ PG+I+WQL+L LLFAW LCYFCIWKGVKWTGK+VYFTALFPYVLLL L IRG+TL G+++GI FY+ P + KL +S+VW+D ATQIFFSYGLGLG  IALGSYN+Y NN ++DALI+  VN+ TS+FAGFV+FSV+GFMA QQ K V +V  SG GL FL YPSA+ QLP S  W+ILFFLMI+FLGLDSQFCT+EGF+TA +DEWP   R+ +++ + VVC +SYLIGL+ +T+GG YVF+L D+YSASGM LLFLIFC+CIAFSW YG+NRF  D N M+G+    +WK+CWLIF+PL+C  VLIFS++ Y+  KY D EY  WA  IG F+ALSS++++P Y+ Y         ++   +L      F+P  + I  DK E + 
Sbjct:   41 MGDITV---DDDVPSRGNWTGKLDFIISCVGYAIGLGNVWRFPYLCYKNGGGAFLVPYFLTLFFAGIPMFLLESSIGQYLSIGGLGVWKLCPIFKGVGYAAAVVAFWLNIYYIVILAWALYYLVSSFQAV-LPWASCDNWWNTEWCRSDYVAPNCTTAFQNQLNETLVTINASLISSLGGTDDVTVYTSQNSSSINATTTALCQ--TNFTSPVREFWERNALRITNGIDEPGNIRWQLSLTLLFAWALCYFCIWKGVKWTGKVVYFTALFPYVLLLVLLIRGVTLPGASQGIWFYIYPKMEKLGDSQVWIDAATQIFFSYGLGLGAVIALGSYNRYHNNVYKDALIVCTVNSCTSMFAGFVIFSVVGFMAEQQQKPVSEVAASGPGLAFLAYPSAIVQLPLSPLWAILFFLMILFLGLDSQFCTMEGFITACVDEWPRVLRKRKEIFIAVVCLISYLIGLACITEGGMYVFQLMDYYSASGMCLLFLIFCECIAFSWAYGVNRFYDDINDMIGYYPCPFWKYCWLIFTPLICGGVLIFSIVQYKSPKYLDYEYPWWADMIGWFMALSSILVVPSYMIYRLASTPGDFRSRCKVL------FRPDIDSIRPDKGEPLS 645          
BLAST of slc6a-1 vs. TrEMBL
Match: V5YTB4 (Transporter OS=Bathymodiolus septemdierum OX=220392 GN=SLC6A1 PE=2 SV=1)

HSP 1 Score: 624.78 bits (1610), Expect = 0.000e+0
Identity = 334/594 (56.23%), Postives = 436/594 (73.40%), Query Frame = 3
Query:  126 QMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSD---NNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNE 1898
            Q+E       S     T ++    D  R QWS+K +F+LS +G CVGLGN+WRFPYLCY+NGGGAFL+PYLLT +FAG+P+  +EL +GQ  SIGGLGVWK C +FKGVGYAA +MA WL+ YYIVILA+A  Y+ NSFT + LPWS CN+ WNT+ C SD    +    C+N  N ++   M  N +    +     SPV EFWER VL  SSG++ PGSI+WQ+AL LL  WILCYFCIWKGVKWTGK+VYFTA FPY+LL+ L IRG+TL G+AEGIKFY+ P+I++L++S+VW+D ATQIFFSYGLGLG+ IALGSYNKY NN ++DA++I ++N+ TS+FAGFV+FSV+GFMAH+QN+ V +V  SG GL FL YPSA+ QLP S  WSILFFLMI+ LG+DSQFCT+EGF TA+IDE+PH  R+ R+L +  VC +SYL+GLSMVT+GG YVF+LFD+YSASG+ LL LIF +CIA  W YG++RF  +   M G+  S ++KF W+I +P + + +L+FS++ ++ VKY D  Y TWAH +G F+A+SSV +IP Y+ Y             +I E ++ +F+P  E
Sbjct:    2 QIEKYELEPLSDNRQSTTSNDNDGDTKRTQWSNKFEFILSCVGFCVGLGNVWRFPYLCYKNGGGAFLVPYLLTALFAGLPMYFMELALGQWLSIGGLGVWKICPIFKGVGYAAAVMAAWLNSYYIVILAWAVYYLINSFT-SVLPWSSCNNEWNTKQCMSDYRRQSTPVNCSNETN-LMGLNMSANATLCLQDDINSTSPVREFWERHVLQISSGVDEPGSIRWQIALCLLLVWILCYFCIWKGVKWTGKVVYFTATFPYILLIILLIRGVTLPGAAEGIKFYILPDINRLQDSQVWIDAATQIFFSYGLGLGSLIALGSYNKYHNNVYKDAMMISLLNSCTSIFAGFVIFSVIGFMAHEQNQPVSEVAASGPGLAFLAYPSAVIQLPISPLWSILFFLMILMLGMDSQFCTMEGFFTALIDEFPHHLRKRRELFIGFVCFLSYLVGLSMVTEGGMYVFQLFDNYSASGLCLLTLIFFECIAIGWGYGVDRFYDNLKSMFGYYPSVFFKFSWVISTPALSLGILLFSLVKFKPVKYLDYSYPTWAHVVGGFMAMSSVSIIPIYMIYKCI------TTPGTIEERVKKLFRPNIE 587          
BLAST of slc6a-1 vs. Ensembl Cavefish
Match: slc6a1l (solute carrier family 6 member 1, like [Source:ZFIN;Acc:ZDB-GENE-041210-296])

HSP 1 Score: 552.362 bits (1422), Expect = 0.000e+0
Identity = 280/573 (48.87%), Postives = 391/573 (68.24%), Query Frame = 3
Query:  108 DLSSAKQMESSIASSKSQLGDKTLTSTEGTDN----HREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFY 1814
            DL+S  +++ ++   +    + ++T  E         R  W  K DF+LS IG  +GLGN+WRFPYLC +NGGGAFLIPY  TLVFAG+P+ LLE  +GQ  S+GGLGVWK   + KGVG AA +++FWL+IYYI+I+++A  Y+F+SFT + LPW  C +PWNT+ C S+ ++    N +                        S V EFWER +   + G+E PG ++W L   L  AW+L YF IWKGV+WTGK+VYF+A +PY +L  LF RG+TL G+ +G+ FY+ P+ +KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RDA+I+  +N+ TS+FAG V+FS++GFM++   K ++++  SG GL FL YP A+ QLP S+ WSILFF M++ LGLDSQFCT+EGF+TA++DE+P   R+ +K+ + +VC +S+LIGLS +TQGG YVF+LFD+YSASGM LLFL+F + +A +W YG +RF  +  +M+G+    WWK CWL F+PL+C+ V  FS +    +      Y  W   IG  +ALSS+++IPGY+ Y
Sbjct:   10 DLNSPSEVKQAVPFEEM---NHSMTPPEEEKKSELPDRGTWKGKFDFLLSCIGYAIGLGNVWRFPYLCGKNGGGAFLIPYFTTLVFAGIPLFLLETALGQYTSVGGLGVWKLIPMMKGVGLAAAVLSFWLNIYYIIIISWALYYLFSSFT-SELPWQSCENPWNTESCFSNYSLPDTTNLT------------------------SAVTEFWERNMHQLTDGLEEPGELRWPLVGTLALAWVLVYFSIWKGVEWTGKVVYFSATYPYFMLFILFFRGVTLPGAIDGVLFYITPDFNKLLKSEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYRDAVIVCCINSFTSMFAGIVIFSIVGFMSNITKKPIQELAASGPGLAFLAYPQAVTQLPMSSLWSILFFSMLLMLGLDSQFCTVEGFITALMDEYPSVLRKRKKVFILIVCIISFLIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFETVAIAWFYGADRFYSNIEEMIGYRPCGWWKLCWLYFTPLICLGVFTFSAIEMTPLTLGKYVYPAWGQGIGWLMALSSMVLIPGYVIY 554          
BLAST of slc6a-1 vs. Ensembl Cavefish
Match: slc6a1b (solute carrier family 6 member 1b [Source:ZFIN;Acc:ZDB-GENE-041114-57])

HSP 1 Score: 551.592 bits (1420), Expect = 0.000e+0
Identity = 281/550 (51.09%), Postives = 383/550 (69.64%), Query Frame = 3
Query:  111 LSSAKQMESSIASSKSQ-LGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHA 1757
            L+   +  +  A+ K + L  K     +  D  RE W+ K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+A+A  Y++NSFT + LPW  C++PWNT  C S+ ++ +  N +                        S V+EFWER +   ++G+E PG ++  LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY +LL LF RG+TL G+ EGI FY+ P+  KLKES+VWLD ATQIFFSYGLGLG+ IALGSYN + NN ++D++I+  +N+ TS+FAGFV+FS++GFM+H   + + DV KSG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R++ + VVC +SY+IGLS +TQGG YVF+LFD+YSASGM LLFL+F +CI+ SW YG+N+F  +  +M+G+    WWK CW++F+PL+   V +FS +    +   +  +  W   
Sbjct:   16 LTEVNEAAAPTANDKPKTLVVKVQKKKDLPD--RETWAGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLETALGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIIAWAIYYLYNSFTTD-LPWKSCDNPWNTDRCFSNYSLASTANMT------------------------SAVVEFWERNMHQLTNGLEEPGEVRGPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYFMLLILFFRGVTLPGAKEGILFYITPDFEKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYKDSIIVCCINSFTSMFAGFVIFSIVGFMSHITKRPIADVAKSGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEFPRVLRGRREIFIAVVCLISYIIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECISISWFYGVNKFYGNIEEMIGYKPCIWWKLCWVVFTPLIVAGVFLFSAVQMVPLTMNNYVFPKWGQG 538          
BLAST of slc6a-1 vs. Ensembl Cavefish
Match: slc6a1a (solute carrier family 6 member 1a [Source:ZFIN;Acc:ZDB-GENE-060519-23])

HSP 1 Score: 522.702 bits (1345), Expect = 1.375e-179
Identity = 283/599 (47.25%), Postives = 382/599 (63.77%), Query Frame = 3
Query:   99 NNRDLSSAKQMESSIASSKSQLGDKTLTSTEGTDNH-----REQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDV 1880
             N   S+  Q+ + +    +    KT  S E          RE W+ K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAGVP+ LLE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+++A  Y++NSFT   LPW  CN+PWNT+ C ++ ++    N +                        S V+EFWER V   + G+E PG I+  LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY +L  LFIRG+TL G+ +GI FY+ P+  KLKES+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N++TS+FAGFV+FS++GFMAH   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQ CT++G L+               L +F             + QGG YVF+LFD+YSASGM LLFL+F +CI+ SWCYG+N+F  +  +M+G+    WWK CW+ F+PL+   V +FS +    +   +  +  W   +G  +ALSS+I+IPGY+ Y       ++K   S+L  L  V
Sbjct:    3 TNGTKSTDGQVATELNEVTTNDRPKTEESKEDLKKKKDIPDRETWAGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWALYYLYNSFT-TELPWRSCNNPWNTEKCFTNYSIADTTNLT------------------------SAVMEFWERNVHDITDGLEKPGQIRPHLAITLAVAWVLVYFCIWKGVSWTGKVVYFSATYPYFMLFILFIRGVTLPGATDGIMFYITPDFEKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYRDSIIVCCINSTTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPVSPLWAILFFSMLLMLGIDSQ-CTVDGSLSL------------TDLCVF------------NIFQGGLYVFKLFDYYSASGMCLLFLVFFECISISWCYGVNKFYDNIQEMIGYKPCIWWKLCWVFFTPLIVAGVFLFSAVQMVPLTMNNYVFPAWGQGVGWLMALSSMILIPGYMVYMFLTLKGTYKEVNSLLTCLTCV 551          
BLAST of slc6a-1 vs. Ensembl Cavefish
Match: slc6a6b (solute carrier family 6 member 6 [Source:NCBI gene;Acc:103034481])

HSP 1 Score: 511.531 bits (1316), Expect = 3.989e-174
Identity = 272/588 (46.26%), Postives = 387/588 (65.82%), Query Frame = 3
Query:  144 ASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTN 1895
             S     G +     EG    RE+W+SK+DF+LS  G  VGLGN+WRFPYLCY+NGGGAFLIPY + L   G+P+  LE+ +GQ  S GG+  W K C +F G+GYA++++   L+IYYIVILA+   Y+F  F    LPW+ CN+PWNT+ C  D                  ++ N +        + SPV EFWER VL  S GIE  G ++W LAL LL  W++C+FCIWKGVK TGK+VY TA FP+V+L+ L +RG+TL G+AEGIKFYL PN+++L + +VW+D  TQIFFSY + LG   +LGSYNKYK NC+RD L++G +N++TS  +GF +FSV+GFMA +Q  ++ DV +SG GL F+ YP A+  +P   FW+ILFF+M++ LGLDSQF  +EG +T+++D +P   R+   R++ + +VC VSYL+GL+MVT+GG YVF+LFD+Y+ASG+ LL++ F +CIA +W YG + F      M+G+  + W K+CW + +PL+C+   IFS++ Y+ + Y K  EY  W+  +G  LAL+S+I IP  +     Q      ++  ++E ++ V  P  
Sbjct:   24 PSPGKSPGTRPEDEAEGKHPQREKWASKLDFLLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVALGQFTSQGGITCWEKLCPIFTGIGYASIVIVSLLNIYYIVILAWGLYYLFQCFQPE-LPWASCNNPWNTENCVEDT-----------------LRRNMTLRGANATNFTSPVTEFWERNVLSISDGIEKVGPVKWDLALCLLGVWVICFFCIWKGVKSTGKVVYITATFPFVMLIVLLVRGVTLPGAAEGIKFYLYPNVTRLADPEVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCLLLGGLNSATSFVSGFAIFSVLGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAIVCFVSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECIAVAWVYGADNFYDAVEDMIGYRPNPWMKWCWTVITPLLCVGCFIFSLVKYKPLTYNKIYEYPDWSIGVGWTLALASMICIPMVVVIKIIQ------SDGPLIERIKAVAAPVR 587          
BLAST of slc6a-1 vs. Ensembl Cavefish
Match: slc6a6b (solute carrier family 6 member 6 [Source:NCBI gene;Acc:103034481])

HSP 1 Score: 510.76 bits (1314), Expect = 5.704e-174
Identity = 272/588 (46.26%), Postives = 387/588 (65.82%), Query Frame = 3
Query:  144 ASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTN 1895
             S     G +     EG    RE+W+SK+DF+LS  G  VGLGN+WRFPYLCY+NGGGAFLIPY + L   G+P+  LE+ +GQ  S GG+  W K C +F G+GYA++++   L+IYYIVILA+   Y+F  F    LPW+ CN+PWNT+ C  D                  ++ N +        + SPV EFWER VL  S GIE  G ++W LAL LL  W++C+FCIWKGVK TGK+VY TA FP+V+L+ L +RG+TL G+AEGIKFYL PN+++L + +VW+D  TQIFFSY + LG   +LGSYNKYK NC+RD L++G +N++TS  +GF +FSV+GFMA +Q  ++ DV +SG GL F+ YP A+  +P   FW+ILFF+M++ LGLDSQF  +EG +T+++D +P   R+   R++ + +VC VSYL+GL+MVT+GG YVF+LFD+Y+ASG+ LL++ F +CIA +W YG + F      M+G+  + W K+CW + +PL+C+   IFS++ Y+ + Y K  EY  W+  +G  LAL+S+I IP  +     Q      ++  ++E ++ V  P  
Sbjct:   20 PSPGKSPGTRPEDEAEGKHPQREKWASKLDFLLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVALGQFTSQGGITCWEKLCPIFTGIGYASIVIVSLLNIYYIVILAWGLYYLFQCFQPE-LPWASCNNPWNTENCVEDT-----------------LRRNMTLRGANATNFTSPVTEFWERNVLSISDGIEKVGPVKWDLALCLLGVWVICFFCIWKGVKSTGKVVYITATFPFVMLIVLLVRGVTLPGAAEGIKFYLYPNVTRLADPEVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCLLLGGLNSATSFVSGFAIFSVLGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAIVCFVSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECIAVAWVYGADNFYDAVEDMIGYRPNPWMKWCWTVITPLLCVGCFIFSLVKYKPLTYNKIYEYPDWSIGVGWTLALASMICIPMVVVIKIIQ------SDGPLIERIKAVAAPVR 583          
BLAST of slc6a-1 vs. Ensembl Sea Lamprey
Match: slc6a1a (solute carrier family 6 member 1a [Source:ZFIN;Acc:ZDB-GENE-060519-23])

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 282/537 (52.51%), Postives = 386/537 (71.88%), Query Frame = 3
Query:  207 REQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCH-RDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFY 1814
            R  W  + DF++S +G  +GLGN+WRFPYLC +NGGGAFLIPY LTLVFAG+P+ LLE  +GQ  S+GGLGVWK   +FKGVG A+V+++F+L+IYYIVI+++A  Y++NSFT + LPW DCN+PWNT  C S+ ++    N +                        S V+EFWER +   SSG++ PG ++  LA+ L  +W++ YFCIWKGV WTGK+VYF+A FPYV+L  LF RG+TL G+ EGI FY+ P+  +L +S VWLD ATQIFFSYGLGLG+ +ALGSYN + NN + RD++I+  +N+ TS+FAGFV+FS++GFM+H   K VK++  SG GL FL YP A+ QLP S  WSILFF M++ LGLDSQFCT+EGF+TA+ DE+P   R H+++ + V+C +SY+IGL+ +TQGG YVF++FD+YSASGM+LLFL+F + IA SWCYG++RF  +  +M+G  + KWW  CW+ F+PLV + V +FSV+    +      Y  W   +G F+ALSS+++IPGY+ Y
Sbjct:   10 RGAWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLVFAGIPLFLLETSLGQYTSVGGLGVWKLAPMFKGVGLASVVISFYLNIYYIVIISWAIYYLYNSFT-SMLPWQDCNNPWNTDKCFSNYSILDTTNLT------------------------STVVEFWERNMHQLSSGLDEPGQVRGPLAITLAISWVMVYFCIWKGVAWTGKVVYFSATFPYVMLFVLFFRGITLPGAKEGILFYITPDFRRLTDSAVWLDAATQIFFSYGLGLGSLVALGSYNPFHNNVYNRDSIIVCCINSVTSVFAGFVIFSIVGFMSHITKKPVKELAASGPGLAFLAYPQAVTQLPISPLWSILFFSMLLMLGLDSQFCTVEGFVTALSDEYPQYLRGHKEIFIAVICVISYIIGLANITQGGLYVFKMFDYYSASGMSLLFLVFFETIAISWCYGVDRFNDNICEMIGHKVHKWWNICWVFFTPLVVVGVFMFSVVEMTPLTLGSYTYPMWGQGMGWFMALSSMLLIPGYMVY 521          
BLAST of slc6a-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008631.1 (pep scaffold:Pmarinus_7.0:GL483327:11244:21649:-1 gene:ENSPMAG00000007785.1 transcript:ENSPMAT00000008631.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 400.593 bits (1028), Expect = 2.988e-133
Identity = 220/503 (43.74%), Postives = 333/503 (66.20%), Query Frame = 3
Query:  315 GAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLF--VVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDK-EYATWAHAIGIFLALSSVIMIPGYIFY 1814
            GAFL+PY LT+V  G+P+  LE+ +GQ+   G +GVWK   +F GVG A++++ F   +YYIV+LA++  Y+ +S T   LPW+ C   W T  C+     +   +N+  G              + C+   SP +EFWER VL  SSG+   GS+ W++ L LL  W+L YF +WKG+K++GK+VY T   PYVLLL L ++G+ L G+ +GI +YL+P+ +KL   +VW++ +TQ+F+ YG+G G   ALGSYNK+ NNC+RD++I+ ++N++TS F+GFVVFS +GFMA +Q  ++  V ++G GL+F+VYP A++ LP  A W+ L F+M++ LG+DS+F  +EGF+T + D +P +    R+   F  + C VS+L+ ++MVTQGG YVF+LFD Y+ASG+++L+L+  +CIA +W YG NRF++D   MLGF    W  +CW + SP VC+ + +F ++ YE + Y  + EY  WA A+G  LALSS++ IP    Y
Sbjct:    1 GAFLVPYGLTVVCVGIPLFFLEVALGQLTQQGTIGVWKIVPLFTGVGVASMVVVFLSDLYYIVVLAWSLYYLLHSLTTAQLPWTHCQGWWATAACSDTLGTSRAASNASEG-------------ASACQDTTSPAVEFWERNVLRVSSGMHDLGSVNWEMLLCLLAVWLLVYFSVWKGIKFSGKVVYVTGSVPYVLLLVLLVQGVMLPGALDGITYYLQPDWAKLATPQVWVEASTQVFYCYGVGFGVLPALGSYNKFHNNCYRDSIILTIINSATSFFSGFVVFSFLGFMAQEQGVDISHVAETGPGLVFVVYPRAISLLPVPALWATLLFIMLLLLGVDSEFAGMEGFVTGLTDLFPSQLSGKRRREAFTGLCCLVSFLLSVTMVTQGGIYVFQLFDSYAASGISMLWLMGWECIAVAWVYGANRFMQDLTAMLGFRPHAWVWWCWSVVSPAVCLGIFVFHLVHYERLVYNGRYEYPGWAEALGWLLALSSMLCIPAVALY 490          
BLAST of slc6a-1 vs. Ensembl Sea Lamprey
Match: slc6a4b (solute carrier family 6 member 4b [Source:ZFIN;Acc:ZDB-GENE-060314-2])

HSP 1 Score: 374.785 bits (961), Expect = 3.181e-123
Identity = 212/504 (42.06%), Postives = 312/504 (61.90%), Query Frame = 3
Query:  315 GAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKY-CLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVL--GESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKS-GQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFY 1814
            GAFLIPY L  VF G+P+  +EL +GQ    G + +W+  C +FKGVG+A  I+ F+++ YY  I+A+A  Y+++SFT + LPW+ C++PWNT  C S  + T +     +                      SP  EF+ R VL    S G+   G ++WQL L L   + + YF +WKGVK +GK+V+ TA FPYV+L  L IRG TL G+  G+ FYLKPN  KL  ++VW+D A QIFFS G G G  +AL SYNK+ NNC+RDAL+   VN  TS  +GFV+F+V+G+MA  +N EV+DV K  G  L+F+ YP A+A + GS FW+ILFF+M+I LGLDS F  LE  +TA++DE+P  F + R+  +  +  + ++  LS +T GGAY+ +L + +  SG +++ ++  + IA SW YG+ RF  D + MLGFS   +W+ CW+  SPL   F+++  +   + +K  D ++  W+  +G F+A SS + +P Y+ Y
Sbjct:    1 GAFLIPYCLMAVFGGIPLFYMELALGQFHRNGAISIWRRICPIFKGVGFAICIINFYVAFYYNTIIAWALYYLYSSFT-STLPWTKCDNPWNTVNCTSYFDTTGVAWGKHS---------------------RSPAEEFYTRNVLEIQYSKGLGGVGGLRWQLLLCLFLIFTIVYFSLWKGVKTSGKVVWVTATFPYVVLFILLIRGATLPGAWRGVLFYLKPNWKKLLTTEVWVDAAAQIFFSLGPGFGVLLALASYNKFNNNCYRDALVTSSVNCFTSFMSGFVIFTVLGYMAEMRNVEVEDVAKDMGPSLLFITYPEAIANMMGSTFWAILFFMMMITLGLDSTFGGLEAIITAVMDEYPSLFSKRREYFVLGLVTICFMGALSTLTYGGAYIVKLLEEF-GSGCSIIGIVLLEAIAVSWFYGVKRFCADIHSMLGFSPGYFWRLCWVAISPLFLSFIVVSFLTGSKPLKLFDYDFPDWSMILGYFIAASSFMFVPLYMAY 481          
BLAST of slc6a-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004857.1 (pep scaffold:Pmarinus_7.0:GL478393:33260:48162:-1 gene:ENSPMAG00000004412.1 transcript:ENSPMAT00000004857.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 297.36 bits (760), Expect = 4.144e-95
Identity = 160/346 (46.24%), Postives = 228/346 (65.90%), Query Frame = 3
Query:  864 KIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCY-GINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQP 1889
            ++VYFTA FPY++L+ LFI GMTL GS +GI +YLKP+ SKL + +VW+D  TQIFFSY +GLG   ALGSYN++ NNC+RD  I+ +VN+ TS FAGFVVFS +GFMA +Q  ++  V +SG GL F+ YP A++ +P +  W+ LFF M+I LGLDSQF  +EGF+T I D +P        R++ + V C  S+LI +SMVT+GG YVF+LFD+YSASGM LL+    +CI  +W Y G +RF+ +   M+G+    W ++CW   +P VC  + +F++L+Y+ + Y K   Y  W  A+G  +ALSS++ IP    Y         + + ++LE  R +  P
Sbjct:    1 QVVYFTATFPYLVLIILFINGMTLPGSYDGIMYYLKPDWSKLGQPQVWIDAGTQIFFSYAIGLGALSALGSYNRFNNNCYRDTFILALVNSGTSFFAGFVVFSTLGFMAAEQGVDISQVAESGPGLAFIAYPKAVSLMPMAPLWAALFFFMLILLGLDSQFVGVEGFVTGISDLFPAALTGGYRREVFVGVCCFTSFLIAISMVTEGGMYVFQLFDYYSASGMTLLWQAGWECIVVAWVYAGGDRFMDNIALMIGYRPFPWMRWCWAFVTPCVCTGIFLFNLLNYKPLTYNKGYVYPWWGEALGWCMALSSMLCIPVVAIYRL------ARTKGNLLERWRILTTP 340          
BLAST of slc6a-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001684.1 (pep scaffold:Pmarinus_7.0:GL482707:4904:15978:1 gene:ENSPMAG00000001516.1 transcript:ENSPMAT00000001684.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 188.348 bits (477), Expect = 2.114e-55
Identity = 111/271 (40.96%), Postives = 167/271 (61.62%), Query Frame = 3
Query:  198 DNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYL--KPNISKLKESKV 1004
            +  R  W+SK +++LS IG  VGLGN+WRFPYL Y+NGGGAFLIPY++ L F G+P+  LE  IGQ  S+G + +WK   + KG+G+  VI +  +++YY  I+AY   Y+F SFT + LPWS C   W       D +V   CN+S          +   +  +   +  +P  ++W ++ L  S  ++  G + W LAL LL +WI+    + KG+K +GK+VYFTA+FPYV+L+ L IRG TL G+  GI++Y+  + N +KL+ ++V
Sbjct:    3 NAERGNWASKSEYMLSMIGNAVGLGNLWRFPYLAYKNGGGAFLIPYIIMLAFVGLPLFFLECSIGQFASLGPITIWKVVPLLKGLGWMMVITSSLIALYYNSIIAYGLFYLFASFT-SELPWSSCKKWWGADENCFDRSV---CNSS----------LAEGNCSSVNSSKQTPSEQYWNKYALRRSESMDETGDVVWHLALTLLLSWIVTCAALVKGIKSSGKVVYFTAIFPYVVLIILLIRGATLPGAILGIEYYIGRQSNFTKLQSAEV 259          
BLAST of slc6a-1 vs. Ensembl Nematostella
Match: EDO32356 (Transporter [Source:UniProtKB/TrEMBL;Acc:A7SVA2])

HSP 1 Score: 493.426 bits (1269), Expect = 4.271e-168
Identity = 276/568 (48.59%), Postives = 381/568 (67.08%), Query Frame = 3
Query:  204 HREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWER---FVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ-HRKLLLFVVCGVS-YLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYK-DKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQP 1889
             RE W  K+DF+L+ IG  VGLGNIWRFPYLCY+NGGG FLIPYL+ L+ AGVP+L+LE+ +GQ  S GG+  WK C +F+G+GYA+V++  +L+IYYIVIL +AF YMF+SF    LPWS C++ WNT+ C+                +  KM   F+     C+ +       W+    +VL  S G++  G+I WQ+AL LLFAWI+CY C++KGVK TG++VYFTA FPYVLL  + +R +TL G+ EGI+FYL+P+ S+L++  VWL  ATQ+FFSY +GLGT IALGSYNK+KNNC+RD +I   VN+ TS + GFV+FSV+GFMA +Q   +++V +SG GL F+ YP+A+A++P S  WSILFF M+I LGLDS+F  +EGF+TAI+D +P   R+ +RK +    C    + IGL MVT+GG YVF+LFD+YSASG+ LL++   + I   W YG  RF ++   M+GF I+ + K CW+  +P+ C+ V IFS+++YE + Y    +Y  W  AIG  LALSS++ IP          I   + E   ++ LR V  P
Sbjct:    8 ERETWVGKLDFILALIGFSVGLGNIWRFPYLCYKNGGGCFLIPYLICLLLAGVPLLILEVCLGQFMSQGGITAWKICPLFQGIGYASVVIVQYLNIYYIVILGWAFYYMFHSFQ-AVLPWSHCDNDWNTEKCH----------------VGRKMITTFNSGSKCCQLFIKSFKCLWKDAADYVLNISGGLDQIGTINWQMALCLLFAWIVCYLCVFKGVKSTGRVVYFTATFPYVLLTIICVRAVTLPGAREGIRFYLEPDWSRLQDGSVWLQAATQVFFSYSIGLGTLIALGSYNKFKNNCYRDCIIFACVNSGTSFYGGFVIFSVLGFMAEKQGVPIQEVAESGPGLAFIAYPAAVAEMPISPLWSILFFFMVILLGLDSEFVGVEGFVTAIVDMFPGYLRRGYRKEIFIAACSTFWFFIGLVMVTEGGMYVFQLFDNYSASGICLLWISLFESIGIGWVYGAERFYQNMTDMIGFRINPYLKVCWIFCTPIFCLAVFIFSLVNYEPLTYNLTYKYPVWGDAIGWLLALSSIVCIP------LLAVINLMRAEGDFIDRLRSVTTP 552          
BLAST of slc6a-1 vs. Ensembl Nematostella
Match: EDO31545 (Transporter [Source:UniProtKB/TrEMBL;Acc:A7SXK0])

HSP 1 Score: 476.863 bits (1226), Expect = 1.324e-161
Identity = 262/596 (43.96%), Postives = 390/596 (65.44%), Query Frame = 3
Query:  195 TDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNS----DNNVTALCNNSDNGILDSKMK------MNFSHLCTEC---KAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKS-ILEILRDVFQ--PTNEDITDKKENIQM 1931
            T N RE W  K DF+LS IG  VGLGN+WRFPYLCY NGGGAFL+PYL+ LV  G+P+  +EL  GQ  S+G +GVW   C +F+G+G+A+++++F + +YY VI+A+   ++  SF    L W  C++ WNT  C +    ++   +L + S+N +++S +        N ++  TEC   +   SP LEFWE ++L  S GI   G I+WQ+ + L+ AW+  YFC+WKGVK +GK+VYFTA FPY++L  LF+RG+TL G+ +GI FYLKP   +LK+ KVW+  ATQIF+S G+G G+ +A+GSYNK+ NN  +DA+ I ++N  TS+FAGFV+FS +GFM+H  NK +++V  SG GL F+VYP A+AQ+P S  W+ILFF MI+ LGLDSQF  +E  +T IIDE+P   R+ ++L + V C + +L+G++ VTQGGAYV  LFD Y + G++LLFL F + +  +W YG +RF KD   M+G   + WW+F W   +P V   +  +S++ ++ V Y   +Y  WA   G  +ALSS++ IPG   Y  ++   + +   + +L+  R++ Q     E ++ + E +++
Sbjct:    2 TTNERETWGKKADFLLSCIGFAVGLGNVWRFPYLCYANGGGAFLLPYLIMLVLCGMPMFFMELSAGQYFSLGPIGVWGAICPLFRGIGFASIVISFLVCVYYNVIIAWCLYFLAVSFRSEVL-WKHCDNWWNTDNCYAGRIPESMSCSLGSGSNNSLVNSTLANATVLAANATNATTECLFPENQVSPSLEFWENYILRLSDGIGEAGEIRWQILVCLILAWVGVYFCMWKGVKSSGKVVYFTATFPYLVLFILFVRGVTLPGADKGIAFYLKPEWHRLKDPKVWVAAATQIFYSLGIGFGSLVAMGSYNKFHNNIFKDAISISLINCGTSVFAGFVIFSTLGFMSHVLNKPIEEVANSGPGLAFVVYPEAIAQMPISPLWAILFFFMILTLGLDSQFGMMEAVITGIIDEYP-VCRKRKELFIAVACFLCFLLGITNVTQGGAYVLNLFD-YQSGGVSLLFLGFFETVCLAWIYGADRFSKDIEDMVGSRPAAWWRFTWKFCAPTVMAGIFFYSIIFWQGVSYGSYKYPQWAEFFGWVIALSSMLFIPGNAIYMIWKTPGTLRERVTFLLKPDRNILQEIERREGLSKRVEVLKV 594          
BLAST of slc6a-1 vs. Ensembl Nematostella
Match: EDO49218 (Transporter [Source:UniProtKB/TrEMBL;Acc:A7RHF4])

HSP 1 Score: 454.136 bits (1167), Expect = 1.136e-152
Identity = 257/613 (41.92%), Postives = 372/613 (60.69%), Query Frame = 3
Query:  120 AKQMESSIASSKSQLGDKTLTSTEGTD-------NHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWK-YCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQC-CNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNED--ITDKKENI 1925
            A+  E +  +       + LTS E            RE+W  KV+F L+ +G  VGLGN+WRFPYLC++NGGGAFLIPYL  L+  G+P+  +EL +GQ  S+G +  W   C + KGVG+A ++++F   +YY VI+A+   Y+F SF  + +PW  C++ WNT   C S+   TAL                        K ++SP  EF+E +VL  +  I+T G ++WQL + L+ AW+L YFC+WKG+K +GK+VYFTA FPY++L+ L IRG+TL G+ +G+ FYLKPN SKL ++ VW+D ATQIF+S G+G G+ IA+GSYNK+ NNC RDA+ + V+N STS+FAG V+FSV+GFMA    KEV +V  SG GL F+VYP  +AQ+P S FWSI FF M++ LGLD+QF   E   T + DE+    R  ++L    +C   +L+GL +V+Q GA++  L+  + A G++L+FL F + I  +W YG +RF  D   M G  +  WW   W   +P V   + IFS++ ++ V Y D +Y  WA  +G  +ALSS++ IPG   Y         + + + +E  R + +P  E   I + +E I
Sbjct:    2 AEPDEKTKIAVNGDADGEGLTSDENCKIDVEIIGEEREKWGRKVEFFLACVGYAVGLGNVWRFPYLCFKNGGGAFLIPYLCMLLICGMPLFFMELSLGQFVSLGPVTSWAAICPISKGVGFAMLVVSFLCCVYYNVIIAWCLYYLFESFAKD-VPWKTCDNWWNTATNCTSNLTDTAL------------------------KEYSSPSKEFYENYVLRITPDIDTFGVMRWQLVVCLILAWVLVYFCLWKGIKSSGKVVYFTATFPYLVLVILLIRGLTLPGAMKGLSFYLKPNFSKLGDAIVWVDAATQIFYSLGIGFGSLIAMGSYNKFHNNCFRDAMTVSVINCSTSVFAGLVIFSVLGFMAEVLGKEVSEVATSGPGLAFVVYPEGIAQMPISPFWSICFFFMLLTLGLDTQFAMFEAVTTGLGDEYVRLLRNRKELFTAFLCFCCFLLGLPIVSQSGAFIMNLY-VWQAGGVSLVFLAFFEVIVVAWGYGADRFALDIETMTGNKVWPWWPIAWKYITPAVITGIFIFSLVQWQGVSYDDYQYPPWAEFVGWVMALSSMLWIPGVAIYKM------SRAKGTFMERWRSLTRPDQEQMSIIELREGI 582          
BLAST of slc6a-1 vs. Ensembl Nematostella
Match: EDO39707 (Transporter [Source:UniProtKB/TrEMBL;Acc:A7S977])

HSP 1 Score: 454.136 bits (1167), Expect = 1.378e-152
Identity = 246/602 (40.86%), Postives = 367/602 (60.96%), Query Frame = 3
Query:  108 DLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWK-YCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWP--HKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQ---------IISHKNEKSILEILRD 1877
            ++  +   +  +  S S   D      E  +  R++WSSK +F+LS++G CVG GN+WRFPYLCY+NGG  FLIPY + L+  G+P+  LEL IGQ  S G +GVWK  C + KG+GYA  ++++   IYYIVILA+ F Y+F SF    +PW  C++PWNT+ C +  +   L N ++         ++    CT      SP  EFW   VL  +  I   G ++W L    + +WI+ YFC++KG+K +GK+VYFTA FP+++L  L IRG TL GS +G+ +YL P+  +L + +VW+  ATQI++S G+G G  I  GSYNK+ NN H+DAL+I + N STS FAGFVVFSV+GFMA   +  V  V  SG GL F+ YP A++Q+P S  W++LFF M+I LGLDSQF T+E  +TAI+DE+P     +  + + + ++C    ++GL  V QGG ++F L D Y  +G++LL +   + I   W YG++RF  D   M G    +W++ CW   SPL  + +++ +++ ++ VKY  K Y  WA  IG  L LSSV+MIP +  +  +++          +   +E+++ +I+RD
Sbjct:    7 EIEESNDTKKPLFGSTSSSEDSPQIDVE-EEQTRDKWSSKAEFMLSSLGYCVGFGNVWRFPYLCYKNGGATFLIPYFIMLIVNGIPLFFLELAIGQWFSSGVIGVWKSICPLLKGIGYAICMISYLCCIYYIVILAWTFYYLFMSFQ-AVVPWKTCDNPWNTKFCRAKRSGDLLLNCTE---------LDLPQNCTAKP--TSPSGEFWSNNVLEMTEDISDFGDMRWPLFGTFILSWIVVYFCLFKGIKSSGKVVYFTATFPFIVLFILMIRGATLEGSLDGVIYYLNPDWERLADPQVWIYAATQIYWSLGVGFGALITFGSYNKFNNNVHKDALVISIANCSTSFFAGFVVFSVLGFMALTLDTTVAKVATSGPGLAFVAYPEAISQMPVSTLWAVLFFFMLITLGLDSQFATIEAVITAIVDEYPWVRGTKWRKPVFVLILCISLCILGLPCVFQGGMWIFNLMD-YQVAGLSLLIVALLEIITIGWIYGVDRFSDDVEYMTGRRPMRWFRICWKYVSPLCTLAIILANLIQWKGVKYNGKPYPGWAELIGWMLMLSSVLMIPAFAIHEIYKRSGTLRERITFLLKPDEEALSKIMRD 594          
BLAST of slc6a-1 vs. Ensembl Nematostella
Match: EDO40151 (Transporter [Source:UniProtKB/TrEMBL;Acc:A7S7X6])

HSP 1 Score: 442.965 bits (1138), Expect = 1.127e-148
Identity = 229/558 (41.04%), Postives = 357/558 (63.98%), Query Frame = 3
Query:  168 DKTLTSTEGTD----NHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQ 1826
            +K L + E  D      RE+W  K++F+ + IG  VG GN WRFPY+C++NGGGAFLIPY+L L   G+P+  +EL +GQ+   G +  W K C +F G+G+A+++++F +SIYY VILA++  +++NSF  + +PW  C+H WNT  C   N      + + +G+  S+                    EF  + VL  +  IE PG +   L L LL AWIL YF IW+G++ TGK+VY TA  PY++L+  FI+G+TL G+ +G+ +++ P   +L++ KVW+D A+QI +S  +G G  I   SYN  KNN   DAL+I V+N +TS+FAGFV+F+++G+MAH Q K V +V   G GL+F+VYP+A++QLP    W+++FFLM+I LGLDSQF  +E    A+I++WP +  +HR+L++ V+C V +L+GLS V++GG +VF LFD +S  G++LLF++  + +   W YG  R+  + ++M+G  + +WW  CW   SP++ + + +FS+  Y+ + Y++  Y  WA  +G  LALSS++ IP  + Y  ++
Sbjct:    6 NKPLKNDEKKDLVTVESRERWDRKIEFLFACIGFAVGYGNFWRFPYMCFKNGGGAFLIPYVLFLCLGGIPLFFMELSLGQLLQEGPIKAWQKICPLFSGIGFASIVISFIVSIYYNVILAWSLYFLYNSFFAD-IPWVGCHHSWNTPDCYVYN-----ASANASGVSSSR--------------------EFLVKNVLEITKSIEEPGGLSVHLTLCLLVAWILVYFSIWRGIRTTGKVVYVTATLPYIILVIFFIKGVTLPGAIDGVLYFITPQWDRLQDPKVWIDAASQILYSLTIGFGVLIGFASYNPRKNNVFSDALLISVINCATSVFAGFVIFAIVGYMAHVQEKSVPEVASQGPGLVFIVYPAAISQLPFPQIWAVIFFLMLIALGLDSQFGQVEVVAAALIEQWPRQLHKHRELVVLVICFVMFLLGLSCVSKGGMFVFNLFDSFSC-GLSLLFVVCFELLVIGWIYGARRYADNISQMIGRPVLQWWVICWKYISPIMVLGIFVFSLAKYKRITYENVPYPAWAEGVGWLLALSSMLCIPVTMCYKIYK 536          
BLAST of slc6a-1 vs. Ensembl Medaka
Match: slc6a1a (sodium- and chloride-dependent GABA transporter 1-like [Source:NCBI gene;Acc:101174592])

HSP 1 Score: 581.637 bits (1498), Expect = 0.000e+0
Identity = 296/561 (52.76%), Postives = 396/561 (70.59%), Query Frame = 3
Query:  207 REQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQP 1889
            RE W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAG+P+ LLE  +GQ  SIGGLGVWK   VFKGVG AA +++FWL+IYYIVI+A+A  Y++NSF+ N LPWS C++ WNT+ C ++             ILD+    N +          S V+EFWER +   + G+E PG ++  LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY +L  LFIRG+TL G+ EGI FY+ P+  KLKES+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFM+H   K + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+P   R  R++ + VVC VSY+IGLS +TQGG YVF+LFD+YSASGM LLFL+F +CI+ SW YG+N+F ++  +M+G+    WWK CWL+F+P +   V +FS +    +   D  + +W   +G  +ALSS+++IPGY+ Y       ++K      E  R +FQP
Sbjct:   39 REMWGGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGMPLFLLECALGQYTSIGGLGVWKLAPVFKGVGLAAAVLSFWLNIYYIVIIAWAIYYLYNSFSAN-LPWSSCDNSWNTEKCYTNYT-----------ILDTT---NLT----------SAVVEFWERNMHQMTDGLEKPGQLRVPLAITLAIAWVLVYFCIWKGVSWTGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYITPDFEKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNTFNNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMSHVTKKSIADVAASGPGLAFLAYPEAVTQLPVSPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEFPRVLRGRREIFIAVVCLVSYVIGLSNITQGGIYVFKLFDYYSASGMCLLFLVFFECISISWFYGVNKFYENIEEMIGYKPCVWWKMCWLVFTPFIVAGVFLFSAVQMVPLTMGDYVFPSWGQGVGWLMALSSMVLIPGYMVYMYLGLKGTYK------ERFRIMFQP 568          
BLAST of slc6a-1 vs. Ensembl Medaka
Match: slc6a1b (solute carrier family 6 member 1 [Source:NCBI gene;Acc:101161049])

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 287/603 (47.60%), Postives = 403/603 (66.83%), Query Frame = 3
Query:  114 SSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKEN 1922
             +     S+  + K +     +  T+     RE W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY LTL+FAG+P+  LE  +GQ  SIGGLGVWK   +FKGVG AA +++FWL+IYYIVI+A+A  Y++NSFT + LPW  C + WNT  C ++ ++      +D G L S                   V+EFWER +   + G+E PG+++  LA+ L  AW+L YFCIWKGV WTGK+VYF+A +PY +L  LF RG++L G+ +G+ FY+ P+  KLKES+VWLD ATQIFFSYGLGLG+ IALGSYN + NN +RD++I+  +N+ TS+FAGFV+FS++GFMA+   + + DV  SG GL FL YP A+ QLP S  W+ILFF M++ LG+DSQFCT+EGF+TA++DE+PH  R+ R++ + +VC +SY IGLS +TQGG YVF+LFD+YSASGM+LLFL+F +CI+ SW YG+N+F ++  +M+G+    WWK CW++F+PL+   V +FS +    +   D  +  W   +G  +ALSS+ +IPGY+ Y       ++K    I+     + +        + EN
Sbjct:   16 ETVTDAPSTTPNDKPKTLVVKVQKTKKEIPERETWGGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGMPLFFLETALGQYTSIGGLGVWKLAPLFKGVGLAAAVLSFWLNIYYIVIIAWAIYYLYNSFTTD-LPWKTCGNSWNTDRCYTNYSI------ADTGNLTSA------------------VVEFWERNMHQLTDGLEKPGAVRVPLAITLAIAWVLVYFCIWKGVSWTGKVVYFSATYPYFMLFILFCRGISLPGAIDGVLFYITPDFEKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFHNNVYRDSIIVCCINSFTSMFAGFVIFSIVGFMANVTKRPIADVAASGPGLAFLAYPEAVTQLPVSPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEFPHVLRKRREIFIAIVCVISYAIGLSNITQGGLYVFKLFDYYSASGMSLLFLVFFECISISWFYGVNKFYENIEEMIGYKPCLWWKACWVVFTPLIVAGVFLFSAVQMVPLTMGDYVFPGWGQGVGWLMALSSMTLIPGYMGYLFLTLKGTYKERLRIMIKPLGILKSQENGPDPQTEN 593          
BLAST of slc6a-1 vs. Ensembl Medaka
Match: slc6a1l (sodium- and chloride-dependent GABA transporter 1 [Source:NCBI gene;Acc:101175450])

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 277/569 (48.68%), Postives = 388/569 (68.19%), Query Frame = 3
Query:  108 DLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFY 1814
            DL+S  +++ ++ +        +          R  W  K DF+LS +G  +GLGN+WRFPYLC +NGGGAFLIPY +TLVFAG+P+  LE  +GQ  S+GGLGVW+   + KGVG AAV+++FWL+IYYIVI+A+A  Y+FNSF+ + LPW  CN+PWNT  C S+ ++T   N S                        S V EFWER +   + G+E PG ++W L   L  AW L YF IWKGV+WTGK+VYF+A +PYV+L  LF RG+TL G+ +GI+FY+ P+ +KL  S+VWLD ATQIFFSYGLGLG+ IALGSYN Y N+ ++D++I+  +N+ TS+FAG V+FS++GFM++   K V+++  SG GL FL YP A+ QLP S+ W++LFF M++ LGLDSQFCT+EGF+TA++DE+P   R+ +K+ + +VC +S++IG S +TQGG YVF++FD+YSASGM LLFL+F +  + SW YG  RF K+   M+G+    WWK CWL+F+PL+C+ V  FS +    +      +  W   IG F+A+SS+++IPGY+ Y
Sbjct:   10 DLNSPSEVKEAVPTDNMDGVAPSADKKNEDIPDRGSWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFMTLVFAGIPLFFLETALGQFTSVGGLGVWRLIPMMKGVGLAAVVLSFWLNIYYIVIIAWALYYLFNSFS-SELPWQSCNNPWNTVNCFSNYSLTDTTNLS------------------------SAVTEFWERNMHQLTGGLEEPGELRWPLVGTLALAWTLVYFSIWKGVEWTGKVVYFSATYPYVMLFILFFRGITLPGAIDGIRFYITPDFNKLARSEVWLDAATQIFFSYGLGLGSLIALGSYNPYNNDVYKDSIIVCCINSCTSMFAGLVIFSIVGFMSYITKKPVQELAASGPGLAFLAYPQAVTQLPLSSLWAVLFFSMLLMLGLDSQFCTVEGFITALMDEYPLVLRKRKKVFILIVCFISFIIGFSNITQGGLYVFKMFDYYSASGMCLLFLVFFETTSISWFYGAERFYKNIEDMIGYRPCVWWKLCWLVFTPLICLGVFTFSAIEMTPLTLGKYVFPMWGQVIGWFMAMSSMVLIPGYVIY 553          
BLAST of slc6a-1 vs. Ensembl Medaka
Match: slc6a6b (solute carrier family 6 member 6 [Source:NCBI gene;Acc:101165803])

HSP 1 Score: 508.064 bits (1307), Expect = 7.222e-173
Identity = 274/600 (45.67%), Postives = 390/600 (65.00%), Query Frame = 3
Query:  147 SSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSD----NNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKEN 1922
            S     G +     EG    RE+W+SK+DFVLS  G  VGLGN+WRFPYLCY+NGGGAFLIPY + L   G+P+  LE+ +GQ  S GG+  W K C +F G+GYA++++   L+IYYIVILA+   Y+F  F    LPW+ CN PWNT+ C  D    N    L  N+ N                    + SPV EFWER VL  S+GIE  G ++W LA+ LL  W++C+FCIWKGVK TGK+VY TA FP+V+L+ L +RG+TL G+AEGIKFYL PN+++L++ +VW+D  TQIFFSY + LG   +LGSYNKYK NC+RD L++G +N+ TS  +GF +FSV+GFMA +Q  ++ DV +SG GL F+ YP A++ +P    W+ILFF+M++ LGLDSQF  +EG +T+I+D +P   R+   R++ + V+C +SY++GL+MVT+GG YVF+LFD+Y+ASG+ LL++ F +CIA +W YG + F      M+G+  + W K+ W   +P++CM   IFS++ Y+ + Y K  EY  WA  +G  LAL+S+I IP  +     Q      +E  ++E ++ V  P    ++ + + 
Sbjct:   25 SPGKSPGTRPEDEAEGKAPQREKWASKLDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVALGQYTSEGGITCWAKLCPIFTGIGYASIVIVSLLNIYYIVILAWGLYYLFQCFQPE-LPWAKCNQPWNTEHCIEDTVRRNKTLWLAANATN--------------------FTSPVTEFWERNVLSISTGIEDIGPLKWDLAVCLLVVWVICFFCIWKGVKSTGKVVYITATFPFVMLIILLVRGVTLPGAAEGIKFYLYPNLTRLQDPEVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCLLLGGLNSGTSFVSGFAIFSVLGFMAQEQGVDIADVAESGPGLAFIAYPKAVSMMPMPTLWAILFFIMLLLLGLDSQFVEVEGQITSIVDLYPSVLRKGYRREIFIAVMCFISYILGLAMVTKGGMYVFQLFDYYAASGVCLLWVAFFECIAVAWVYGADNFYDGIEDMIGYRPNPWMKWSWTFITPVLCMGCFIFSLVKYKPLTYNKVYEYPDWAIGLGWCLALTSMICIPMVMVIKILQ------SEGPLIERIKAVAAPAKSGVSSRPKE 597          
BLAST of slc6a-1 vs. Ensembl Medaka
Match: ENSORLT00000012014.2 (sodium- and chloride-dependent taurine transporter [Source:NCBI gene;Acc:101175313])

HSP 1 Score: 504.597 bits (1298), Expect = 1.599e-171
Identity = 270/596 (45.30%), Postives = 384/596 (64.43%), Query Frame = 3
Query:  147 SSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQ--HRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKY-KDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKEN 1922
            S     G +     EG    RE+W+SK+DFVLS  G  VGLGN+WRFPYLCY+NGGGAFLIPY + L   G+P+  LE+ +GQ  S GG+  W K C +F G+GYA++++   L+IYYIVILA+   Y+F  F    LPW+ C  PWNT+ C                I D+  K     +      + SPV EFWE  VLG SSGIE  G+++W LAL LL  W++C+FCIWKGVK TGK+VY TA FP+V+L+ L IRG+TL G+A GIKFYL PN+ +L + +VW+D  TQIFFSY + LG   +LGSYNKYK NC+RD L++G +N+ TS  +GF +FSV+GFMA +Q  ++ DV +SG GL F+ YP A+  +P    W+ILFF+M++ LGLDSQF  +EG +T+++D +P   R+   R++ + ++C +SYL GL+MVT+GG YVF+LFD+Y+ASG+ LL++ F +C+A +W YG++ F      M+G+  + W K+ W + +PL+CM    FS++ Y+ + Y K  +Y  WA  IG  LAL+S+I IP  +     Q      ++  ++E ++ V  P     + +  +
Sbjct:   21 SPGKSPGTRPEDEAEGKHPQREKWASKLDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVALGQFTSEGGITCWEKLCPIFTGIGYASIVIVSLLNIYYIVILAWGVYYLFQCFQPE-LPWAKCKQPWNTERC----------------IEDTYRKNKTLWVAANASNFTSPVTEFWEHNVLGISSGIEEIGAVKWDLALCLLLVWVICFFCIWKGVKSTGKVVYITATFPFVMLIVLLIRGVTLPGAAAGIKFYLYPNLDRLMDPEVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCLLLGALNSGTSFVSGFAIFSVLGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPIPTLWAILFFVMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREVFIAIICCLSYLFGLTMVTKGGMYVFQLFDYYAASGVCLLWVAFFECVAVAWVYGVDNFYDAIEDMIGYRPNPWMKWSWTVVTPLLCMGCFFFSLVKYKPLTYNKVYQYPDWAVGIGWTLALASMICIPMVVVIKIIQ------SDGPLIERIKAVAAPVRGGASSRPAD 593          
BLAST of slc6a-1 vs. Planmine SMEST
Match: SMESG000018924.1 (SMESG000018924.1)

HSP 1 Score: 1184.47 bits (3063), Expect = 0.000e+0
Identity = 606/606 (100.00%), Postives = 606/606 (100.00%), Query Frame = 3
Query:  129 MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIRNV 1946
            MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSIQWQLALALLFAWILCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSILFFLMIIFLGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIRNV
Sbjct:    1 MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSIQWQLALALLFAWILCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSILFFLMIIFLGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQMIIRNV 606          
BLAST of slc6a-1 vs. Planmine SMEST
Match: SMESG000009904.1 (SMESG000009904.1)

HSP 1 Score: 421.009 bits (1081), Expect = 5.662e-140
Identity = 240/584 (41.10%), Postives = 365/584 (62.50%), Query Frame = 3
Query:  207 REQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWP--HKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDK------EYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITD-KKENIQM 1931
            R++W +K+DF+L+ IG  VGLGN+WRFPYLCY+NGGGAFLIPY +++V  G+P+  LE+ +GQ  + GG+ VW    + KG+GYA+V++ F L+ YY VILA+A  Y+  SF   P+ WS CN+ WNT  C++D        NS N    S +K++             P +E+WE  VLG + GIE  G+I+  L   LL AWI+ YFCIWKG+K +G+++YFTA  PYVL++ L IR  TL G+  G+++YL P   +L   +VW+D  TQIFFSY + +GT +ALGSYN + +N  RD ++  VVN+ TS  AGFV+F  +GFM+ +    +++VV SG GL F+VYP ALA++P ++ WS+LFF MII LG+DSQF  +EGF+T+  D +P      +++++ + VVC +++ IGL+MVT GG YVF+LFD+Y  S + ++  +  +C++  + YGI RF ++ N+M GFS+       W   +P+  + + I S + Y  ++YK        ++ +W+  +G  +A S ++ +P          I   +    I+E ++ + QP  + I     E+ QM
Sbjct:    6 RDKWLNKLDFLLACIGFSVGLGNVWRFPYLCYKNGGGAFLIPYFISVVLGGIPMFCLEVFVGQFMARGGIEVWNIVPLMKGIGYASVVVLFMLNCYYNVILAWAIYYLVASFNY-PVSWSHCNNAWNTLQCSTDA-----FKNSTN---SSALKID-------------PAIEYWEHRVLGLNKGIENVGTIKLDLMFCLLAAWIVVYFCIWKGIKTSGRVMYFTATSPYVLMITLLIRVATLPGARMGLEYYLIPKWERLLAMEVWVDSGTQIFFSYSIAIGTLVALGSYNDFHHNSVRDCVLFSVVNSGTSFLAGFVIFMTLGFMSERTGIPIQNVVASGPGLAFVVYPKALAEMPITSLWSVLFFAMIILLGIDSQFVGVEGFITSFNDIFPVWMNIGKNKQIFIAVVCLMNFGIGLTMVTHGGMYVFQLFDYYIGSRIIIIIAVL-ECLSICYFYGIKRFSRNLNEMFGFSLGYIPHIFWGALTPIFLLIIFIMSTIVYSELEYKRGSDNVVYKFPSWSVKVGWTMANSCLVFVP------IIACIGILREGGPIIERIQKLLQPKLKGIEHFTNESHQM 560          
BLAST of slc6a-1 vs. Planmine SMEST
Match: SMESG000021044.1 (SMESG000021044.1)

HSP 1 Score: 418.698 bits (1075), Expect = 1.706e-137
Identity = 234/552 (42.39%), Postives = 336/552 (60.87%), Query Frame = 3
Query:  150 SKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKY-CLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSGIE--TPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYE----HVKYKDKEYATWAHAIGIFLALSS 1784
            S++ +G K   ++     +R+ W  K+DF+LS IG  V LGN+WRFPY+C++NGGGAFLIPY++  +F G+P+  LEL +GQ +  G L VW+  C +F+G+GY   ++A + + YY  I+A++  Y+  S     LPW+ C +PWNT  C +  +     + S   I  + +  N     T  +   S   E++ R VL  + GI+    G I+  + LAL+  + + YF +WKGVK +GK V+ TA  PYV+LL L +RG  L GS  GIK+YLKPN++KL E  VW+D A QIFFS G G G  +AL SY+K++NNC++DALI   +N  TS  AGFVVFSV+G M  + NK + DV     GL+F+ YP A+A L GS  WSILFF+M+I LGLDS F  LE  +T I+DEWP + R+ R+L + ++    ++  L+  TQGG  +    D   A  +++LF++FC+C+A  W YGI RF  D   MLGF    +WK CW   SP   + + + +V+SYE     V  KD E+  W+ A+   + LSS
Sbjct:   84 SENNIGIKVKPTSH---QNRDTWDKKMDFLLSVIGFAVDLGNVWRFPYICFKNGGGAFLIPYIIMYIFGGLPLFFLELALGQYQRCGCLTVWRRICPMFRGIGYGICVIATYTAWYYNTIMAWSLYYLVESIQ-EKLPWTSCGNPWNTNSCITLEDKINF-SRSYRPIYKTIIINNTVLNITVNETLFSSTEEYFYRRVLHITDGIDFNNVGQIEVNVVLALIVIFTIVYFSLWKGVKSSGKAVWITATTPYVVLLILLVRGALLPGSGIGIKYYLKPNMTKLWEKTVWIDAAAQIFFSLGPGFGVLLALSSYSKFRNNCYQDALITSAINCITSFIAGFVVFSVLGHMCWRLNKRMDDVADQQAGLVFIAYPEAIASLTGSVVWSILFFIMLISLGLDSTFGGLEALITGILDEWP-RLRKRRELFVLLLIIYCFIGSLATTTQGGFLILNWLDKNGAP-ISILFIVFCECVALCWFYGIKRFSDDVESMLGFQPPTFWKMCWTYISPAFLLIIFLTNVISYETAPITVMRKDYEFPPWSKALACLVVLSS 628          
BLAST of slc6a-1 vs. Planmine SMEST
Match: SMESG000019713.1 (SMESG000019713.1)

HSP 1 Score: 417.542 bits (1072), Expect = 7.601e-137
Identity = 248/594 (41.75%), Postives = 355/594 (59.76%), Query Frame = 3
Query:  168 DKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWKYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVT------ALCNNSDNGILDSKMKM---NFSHLCTECKAWNSPVLEFWERFVLGESSGIETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRK--LLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGIN--------RFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPT 1892
            ++ L S E  +N R  W  K DF+LS++G  VGLGNIWRFPY+CY NGGGAF+IPYL+ L   G+PI L+++ +GQ  S G    W+Y  +F G+GYA VI++  +++YY VI++YA  YMF S + NPLPW  CN+ WNT  C    ++       A  N +   I D  + +      ++ T+ K    P  E++   VL  S  +   G++QW+LAL L  +WI+ + C+ KG+K TGKIVYFTA+FPY +LL LF RG+ L G+ +GI FY+ P++ KL ++ VW D A QIFFS     G  IAL SYN++ NN  RD LI+ + N++TS+FAGFV+FS +G +A +    V  V   G GL F++YP A+A +PGS  WSILFF+M+I LGLDSQF T+E  +T  +D +P   R  +   +LLFV+  + + +GL + T+ G Y  +L D Y   G A+L +   + I+  W YG          RF +D   +LG  IS WW+ CW   +P +   +++FS   Y   KY DK Y  WA  +G  + + S+  IPG + Y  F++   +    SI  IL+D+  PT
Sbjct:   56 NEYLKSEE--NNERGNWVGKCDFILSSLGYAVGLGNIWRFPYMCYRNGGGAFMIPYLIFLFLIGMPIFLVDVGLGQFTSNGPFTCWEYAPIFTGIGYAMVIISTLVAVYYNVIISYAVYYMFASIS-NPLPWISCNNSWNTDYCRDRLSIVNCSLMKAFSNGTCYDISDKLVGLWNETLFNIITQ-KTRKLPAEEYFNNEVLNLSKDVTIIGAVQWKLALCLFGSWIIVFLCLIKGIKSTGKIVYFTAIFPYFVLLILFFRGVCLDGAIDGIAFYIIPDLKKLSDASVWKDAANQIFFSLSASWGGLIALSSYNRFHNNIIRDTLIVTIGNSATSIFAGFVIFSYLGHLAKRLGTSVSLVADKGMGLAFIIYPEAVATMPGSYIWSILFFVMLITLGLDSQFTTIETVITGFVDVYPIYLRPRKTWFILLFVI--ILFFLGLPLTTKSGPYWLQLMDTY-CGGWAILLIGIFEVISIGWVYGRPGFNWKKPMRFQRDIETILGRPISNWWRLCWQYITPTLMSGIILFSWFDYTRAKYGDKIYPIWADFLGWMMTVLSLAFIPGTVVYLVFKE-RRYNPYHSIKRILQDLTVPT 641          
BLAST of slc6a-1 vs. Planmine SMEST
Match: SMESG000068398.1 (SMESG000068398.1)

HSP 1 Score: 404.445 bits (1038), Expect = 8.664e-133
Identity = 225/566 (39.75%), Postives = 341/566 (60.25%), Query Frame = 3
Query:  102 NRDLSSAKQMESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNIWRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVW-KYCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNHPWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEFWERFVLGESSG--IETPGSXXXXXXXXXXXXXXXCYFCIWKGVKWTGKIVYFTALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVMGFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSXXXXXXXXXXGLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQGGAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSISKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLALSSVI 1790
            NR+     ++E       +   DK     +  D  RE W  K+DF+ S IG  V L N+WRFPYLC++NGGGAFLIPY+L L+F GVP+  +EL +GQ    G +  W + C +FKG+GY+ V++AF+   +Y VI+A++  Y++ S +L  LPW+ CN+ WNT  C   +    L +        + +  NF+           P  E++   VLG+ +G   E  G+IQ  LA+ LL  +++CYF +WKG+  +GK+V+FTALFPYV+L+ +  + + L GS +GI+ Y+ PNI+KL  S+ W+D ATQ+FFS G G G  +   SYNK+ NN  RDALI   VN++TS  +GFVVFSV+GFMA ++   ++DVV    GL+F VYP A + +    FWSI+FFLM++ LGLDS F   E  +T + DE+P   ++ R++ +  +    Y IGL+ VT GG YVF  F+ Y  +  +LL ++ C+ I  SW YG+++F  +  +M+G   + +WK CW   +P+   F ++F ++++ ++      Y  WA+ +G   A SSV+
Sbjct:   15 NRERDETLELEQG-----ANENDKMKIEFDPED--RETWDKKMDFLFSVIGFAVDLANVWRFPYLCFKNGGGAFLIPYILMLIFGGVPLFYMELALGQYVRKGSITCWGRICPLFKGIGYSMVMIAFYTDFFYNVIIAWSIYYLYASLSL-ILPWTICNNKWNTINCYDRH----LQSGGYLSTFQTNLTRNFTIFNVSNPNSTFPADEYYNSHVLGKQAGNNFENLGAIQPHLAICLLLVYVICYFSLWKGISMSGKVVWFTALFPYVVLITMLFKVVFLEGSQDGIRLYIYPNITKLYNSEPWVDAATQVFFSLGPGFGVLLTFASYNKFNNNVFRDALITSAVNSATSFLSGFVVFSVIGFMAKRRGLNIQDVVHEDPGLVFSVYPEAFSTMFPPTFWSIMFFLMLLTLGLDSSFGGSESVITGLSDEFP-ILKRRREIFVLCLFIFYYCIGLTEVTNGGIYVFYFFERYCIN-YSLLLVVMCETICISWIYGVDKFRGNIKEMIGSEPNIYWKICWKFIAPIFIGFNIVFGLVNHSNLTMGGYVYPVWANVLGWMFAFSSVL 566          
The following BLAST results are available for this feature:
BLAST of slc6a-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC6A10.000e+049.16solute carrier family 6 member 1 [Source:HGNC Symb... [more]
SLC6A10.000e+049.16solute carrier family 6 member 1 [Source:HGNC Symb... [more]
SLC6A10.000e+049.16solute carrier family 6 member 1 [Source:HGNC Symb... [more]
SLC6A10.000e+049.16solute carrier family 6 member 1 [Source:HGNC Symb... [more]
SLC6A10.000e+049.16solute carrier family 6 member 1 [Source:HGNC Symb... [more]
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BLAST of slc6a-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snf-110.000e+051.08Transporter [Source:UniProtKB/TrEMBL;Acc:G5EF43][more]
snf-31.795e-13738.66Sodium- and chloride-dependent betaine transporter... [more]
dat-16.636e-13436.96Sodium-dependent dopamine transporter [Source:Uni... [more]
mod-55.164e-11638.10Transporter [Source:UniProtKB/TrEMBL;Acc:Q9N3C7][more]
snf-52.064e-7433.45Sodium-dependent transporter snf-5 [Source:UniPro... [more]
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BLAST of slc6a-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gat0.000e+051.56gene:FBgn0039915 transcript:FBtr0089972[more]
Gat2.399e-16555.27gene:FBgn0039915 transcript:FBtr0089971[more]
DAT8.289e-15842.78gene:FBgn0034136 transcript:FBtr0330002[more]
DAT9.782e-15842.78gene:FBgn0034136 transcript:FBtr0087125[more]
SerT4.495e-14640.72gene:FBgn0010414 transcript:FBtr0072362[more]
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BLAST of slc6a-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc6a1a0.000e+049.01solute carrier family 6 member 1a [Source:ZFIN;Acc... [more]
slc6a1b0.000e+049.92solute carrier family 6 member 1b [Source:ZFIN;Acc... [more]
slc6a1l4.293e-18046.67solute carrier family 6 member 1, like [Source:ZFI... [more]
slc6a1l2.276e-17747.89solute carrier family 6 member 1, like [Source:ZFI... [more]
slc6a85.357e-17147.41solute carrier family 6 member 8 [Source:ZFIN;Acc:... [more]
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BLAST of slc6a-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc6a130.000e+049.31solute carrier family 6 (neurotransmitter transpor... [more]
slc6a130.000e+049.31solute carrier family 6 (neurotransmitter transpor... [more]
slc6a130.000e+049.16solute carrier family 6 (neurotransmitter transpor... [more]
slc6a130.000e+049.74solute carrier family 6 (neurotransmitter transpor... [more]
slc6a8l1.774e-17148.41solute carrier family 6 (neurotransmitter transpor... [more]
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BLAST of slc6a-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Slc6a10.000e+049.33solute carrier family 6 (neurotransmitter transpor... [more]
Slc6a64.805e-16947.76solute carrier family 6 (neurotransmitter transpor... [more]
Slc6a133.309e-16846.22solute carrier family 6 (neurotransmitter transpor... [more]
Slc6a82.045e-15947.31solute carrier family 6 (neurotransmitter transpor... [more]
Slc6a82.045e-15947.31solute carrier family 6 (neurotransmitter transpor... [more]
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BLAST of slc6a-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P23978|SC6A1_RAT0.000e+049.33Sodium- and chloride-dependent GABA transporter 1 ... [more]
sp|P31648|SC6A1_MOUSE0.000e+049.33Sodium- and chloride-dependent GABA transporter 1 ... [more]
sp|P30531|SC6A1_HUMAN0.000e+049.16Sodium- and chloride-dependent GABA transporter 1 ... [more]
sp|P48057|SC6A1_MUSCO0.000e+047.81Sodium- and chloride-dependent GABA transporter 1 ... [more]
sp|Q9MZ34|SC6A6_BOVIN3.449e-17048.38Sodium- and chloride-dependent taurine transporter... [more]
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BLAST of slc6a-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YIU20.000e+0100.00Transporter OS=Schmidtea mediterranea OX=79327 GN=... [more]
R7UHY80.000e+053.81Transporter OS=Capitella teleta OX=283909 GN=CAPTE... [more]
A0A1S3JS620.000e+054.78Transporter OS=Lingula unguis OX=7574 GN=LOC106175... [more]
A0A1S3JR410.000e+054.94Transporter OS=Lingula unguis OX=7574 GN=LOC106175... [more]
V5YTB40.000e+056.23Transporter OS=Bathymodiolus septemdierum OX=22039... [more]
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BLAST of slc6a-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc6a1l0.000e+048.87solute carrier family 6 member 1, like [Source:ZFI... [more]
slc6a1b0.000e+051.09solute carrier family 6 member 1b [Source:ZFIN;Acc... [more]
slc6a1a1.375e-17947.25solute carrier family 6 member 1a [Source:ZFIN;Acc... [more]
slc6a6b3.989e-17446.26solute carrier family 6 member 6 [Source:NCBI gene... [more]
slc6a6b5.704e-17446.26solute carrier family 6 member 6 [Source:NCBI gene... [more]
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BLAST of slc6a-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc6a1a0.000e+052.51solute carrier family 6 member 1a [Source:ZFIN;Acc... [more]
ENSPMAT00000008631.12.988e-13343.74pep scaffold:Pmarinus_7.0:GL483327:11244:21649:-1 ... [more]
slc6a4b3.181e-12342.06solute carrier family 6 member 4b [Source:ZFIN;Acc... [more]
ENSPMAT00000004857.14.144e-9546.24pep scaffold:Pmarinus_7.0:GL478393:33260:48162:-1 ... [more]
ENSPMAT00000001684.12.114e-5540.96pep scaffold:Pmarinus_7.0:GL482707:4904:15978:1 ge... [more]
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BLAST of slc6a-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc6a-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO323564.271e-16848.59Transporter [Source:UniProtKB/TrEMBL;Acc:A7SVA2][more]
EDO315451.324e-16143.96Transporter [Source:UniProtKB/TrEMBL;Acc:A7SXK0][more]
EDO492181.136e-15241.92Transporter [Source:UniProtKB/TrEMBL;Acc:A7RHF4][more]
EDO397071.378e-15240.86Transporter [Source:UniProtKB/TrEMBL;Acc:A7S977][more]
EDO401511.127e-14841.04Transporter [Source:UniProtKB/TrEMBL;Acc:A7S7X6][more]
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BLAST of slc6a-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc6a1a0.000e+052.76sodium- and chloride-dependent GABA transporter 1-... [more]
slc6a1b0.000e+047.60solute carrier family 6 member 1 [Source:NCBI gene... [more]
slc6a1l0.000e+048.68sodium- and chloride-dependent GABA transporter 1 ... [more]
slc6a6b7.222e-17345.67solute carrier family 6 member 6 [Source:NCBI gene... [more]
ENSORLT00000012014.21.599e-17145.30sodium- and chloride-dependent taurine transporter... [more]
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BLAST of slc6a-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000018924.10.000e+0100.00SMESG000018924.1[more]
SMESG000009904.15.662e-14041.10SMESG000009904.1[more]
SMESG000021044.11.706e-13742.39SMESG000021044.1[more]
SMESG000019713.17.601e-13741.75SMESG000019713.1[more]
SMESG000068398.18.664e-13339.75SMESG000068398.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30029272
GenBankAKN21421.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029272 ID=SMED30029272|Name=slc6a-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2006bp
TCCGATCTCAATCATTCCATAAATTATAAATTTTCAAAATCGTTTTCCAT
GGTCAACGTAAACTGACCTCAGTTATTTACAACTATATAACGTAGTGGAA
CAATCGAGATTTGTCAAGTGCAAAACAGATGGAATCATCAATCGCATCGT
CGAAAAGTCAGTTAGGAGACAAAACTTTGACAAGCACAGAAGGAACGGAC
AATCATAGGGAGCAATGGTCATCAAAAGTTGATTTCGTTTTAAGTGCTAT
CGGACTTTGTGTTGGACTAGGTAACATATGGAGATTTCCATACTTGTGCT
ATGAAAATGGTGGAGGTGCCTTTCTAATTCCCTATCTTTTAACATTGGTA
TTCGCCGGAGTTCCAATTTTATTATTGGAGCTAATGATAGGGCAAATGAA
GAGCATTGGTGGTCTCGGTGTTTGGAAATATTGTCTCGTTTTTAAAGGAG
TTGGATACGCTGCCGTTATTATGGCATTTTGGTTAAGTATATATTATATT
GTGATTTTAGCATATGCATTCGTGTACATGTTTAACTCTTTCACATTGAA
CCCTTTGCCATGGAGTGACTGCAATCACCCTTGGAATACTCAGTGTTGTA
ACTCTGACAACAATGTAACCGCATTATGCAATAACTCGGACAACGGCATT
TTGGATTCGAAAATGAAAATGAATTTTTCACACTTATGTACTGAATGTAA
AGCATGGAATTCGCCGGTTCTTGAGTTTTGGGAGCGATTTGTTTTAGGGG
AAAGCAGTGGAATTGAAACTCCAGGTTCTATACAATGGCAATTAGCACTA
GCTTTATTATTTGCATGGATACTATGTTATTTTTGCATTTGGAAAGGTGT
AAAATGGACTGGGAAAATTGTTTATTTTACTGCATTATTTCCATACGTCT
TGTTACTATGCTTATTTATTAGAGGAATGACCCTTACAGGTTCAGCAGAA
GGAATCAAATTTTATCTCAAGCCAAATATTTCAAAATTAAAAGAGTCAAA
AGTATGGCTCGACGGAGCAACTCAAATATTTTTCTCGTATGGACTTGGAT
TGGGAACACATATTGCTCTTGGAAGCTACAACAAATATAAAAACAATTGT
CATCGTGACGCATTAATTATCGGAGTTGTGAACGCATCTACAAGTTTGTT
TGCAGGATTCGTCGTGTTTTCCGTTATGGGATTTATGGCACATCAGCAAA
ATAAGGAGGTGAAAGATGTTGTCAAATCAGGTCAAGGGTTGATATTCCTA
GTTTATCCGTCAGCTTTAGCGCAGTTACCCGGATCAGCTTTTTGGTCAAT
TCTCTTTTTCTTGATGATTATATTTTTGGGATTGGACAGCCAGTTTTGTA
CATTGGAAGGTTTCTTGACAGCTATAATTGATGAATGGCCTCATAAATTT
AGACAGCATAGAAAACTTCTTCTTTTCGTCGTTTGTGGAGTTTCTTATTT
GATCGGATTATCAATGGTTACACAAGGAGGTGCTTATGTTTTTCGATTAT
TTGATCATTATTCTGCTAGTGGAATGGCTCTATTGTTCCTAATATTTTGT
CAATGTATTGCATTTTCATGGTGTTATGGTATCAATAGATTTATTAAAGA
TTGTAATAAAATGCTAGGATTTTCAATTAGTAAGTGGTGGAAATTCTGCT
GGCTCATCTTCTCCCCATTAGTTTGTATGTTTGTGTTAATTTTTTCCGTC
CTCAGTTATGAGCATGTAAAATATAAAGACAAGGAATATGCAACATGGGC
ACATGCGATTGGAATTTTTCTAGCCCTGTCCAGTGTGATTATGATTCCTG
GATATATATTTTACTATACATTCCAACAAATAATATCGCACAAAAATGAA
AAATCAATATTAGAAATCTTAAGAGATGTGTTTCAACCAACCAATGAAGA
TATTACAGACAAAAAAGAAAATATTCAAATGATCATCCGAAATGTTTAAT
AAACTAAGTTACTGAAATTGACTAAATAAGCTTTAGTTTAGCATTTCATT
TTAAAA
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protein sequence of SMED30029272-orf-1

>SMED30029272-orf-1 ID=SMED30029272-orf-1|Name=SMED30029272-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=607bp
MESSIASSKSQLGDKTLTSTEGTDNHREQWSSKVDFVLSAIGLCVGLGNI
WRFPYLCYENGGGAFLIPYLLTLVFAGVPILLLELMIGQMKSIGGLGVWK
YCLVFKGVGYAAVIMAFWLSIYYIVILAYAFVYMFNSFTLNPLPWSDCNH
PWNTQCCNSDNNVTALCNNSDNGILDSKMKMNFSHLCTECKAWNSPVLEF
WERFVLGESSGIETPGSIQWQLALALLFAWILCYFCIWKGVKWTGKIVYF
TALFPYVLLLCLFIRGMTLTGSAEGIKFYLKPNISKLKESKVWLDGATQI
FFSYGLGLGTHIALGSYNKYKNNCHRDALIIGVVNASTSLFAGFVVFSVM
GFMAHQQNKEVKDVVKSGQGLIFLVYPSALAQLPGSAFWSILFFLMIIFL
GLDSQFCTLEGFLTAIIDEWPHKFRQHRKLLLFVVCGVSYLIGLSMVTQG
GAYVFRLFDHYSASGMALLFLIFCQCIAFSWCYGINRFIKDCNKMLGFSI
SKWWKFCWLIFSPLVCMFVLIFSVLSYEHVKYKDKEYATWAHAIGIFLAL
SSVIMIPGYIFYYTFQQIISHKNEKSILEILRDVFQPTNEDITDKKENIQ
MIIRNV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000418head
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR037272SNS_sf
IPR000175Na/ntran_symport
Vocabulary: molecular function
TermDefinition
GO:0005328neurotransmitter:sodium symporter activity
GO:0015293symporter activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0006836neurotransmitter transport
GO:0006810transport
GO:0055085transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000175Sodium:neurotransmitter symporterPRINTSPR00176NANEUSMPORTcoord: 383..402
score: 56.31
coord: 505..525
score: 34.5
coord: 329..349
score: 47.23
coord: 35..56
score: 67.81
coord: 465..485
score: 38.88
coord: 64..83
score: 50.41
coord: 247..264
score: 55.1
coord: 107..133
score: 45.17
IPR000175Sodium:neurotransmitter symporterPFAMPF00209SNFcoord: 27..565
e-value: 2.9E-207
score: 689.5
IPR000175Sodium:neurotransmitter symporterPANTHERPTHR11616SODIUM/CHLORIDE DEPENDENT TRANSPORTERcoord: 16..573
IPR000175Sodium:neurotransmitter symporterPROSITEPS00610NA_NEUROTRAN_SYMP_1coord: 51..65
IPR000175Sodium:neurotransmitter symporterPROSITEPS50267NA_NEUROTRAN_SYMP_3coord: 26..569
score: 101.732
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..24
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..19
NoneNo IPR availablePANTHERPTHR11616:SF265TRANSPORTERcoord: 16..573
NoneNo IPR availableCDDcd11496SLC6sbd-TauT-likecoord: 27..587
e-value: 0.0
score: 784.462
NoneNo IPR availableTMHMMTMhelixcoord: 65..87
NoneNo IPR availableTMHMMTMhelixcoord: 431..453
NoneNo IPR availableTMHMMTMhelixcoord: 36..55
NoneNo IPR availableTMHMMTMhelixcoord: 540..562
NoneNo IPR availableTMHMMTMhelixcoord: 331..353
NoneNo IPR availableTMHMMTMhelixcoord: 247..269
NoneNo IPR availableTMHMMTMhelixcoord: 216..238
NoneNo IPR availableTMHMMTMhelixcoord: 108..130
NoneNo IPR availableTMHMMTMhelixcoord: 380..402
NoneNo IPR availableTMHMMTMhelixcoord: 506..525
NoneNo IPR availableTMHMMTMhelixcoord: 296..318
NoneNo IPR availableTMHMMTMhelixcoord: 463..485
IPR037272Sodium:neurotransmitter symporter superfamilySUPERFAMILYSSF161070SNF-likecoord: 27..565