ANK_REP_REGION domain-containing protein

Overview
NameANK_REP_REGION domain-containing protein
Smed IDSMED30029206
Length (bp)1581
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ANK_REP_REGION domain-containing protein (SMED30029206) t-SNE clustered cells

Violin plots show distribution of expression levels for ANK_REP_REGION domain-containing protein (SMED30029206) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ANK_REP_REGION domain-containing protein (SMED30029206) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ANK_REP_REGION domain-containing protein (SMED30029206) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30029206

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30029206h1SMcG0020688 dd_Smed_v4_5280_0_1dd_Smed_v4PMID:27063937
Scimone et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30029206h1SMcG0020688 SmedASXL_019772SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30029206h1SMcG0020688 dd_Smed_v4_5280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30029206h1SMcG0020688 dd_Smed_v4_5280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30029206h1SMcG0020688 dd_Smed_v6_5280_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30029206h1SMcG0020688 OX_Smed_1.0.20756ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30029206h1SMcG0020688 dd_Smed_v4_5280_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: CASKIN1 (CASK interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20879])

HSP 1 Score: 66.6254 bits (161), Expect = 9.332e-11
Identity = 43/141 (30.50%), Postives = 75/141 (53.19%), Query Frame = 3
Query: 1050 KKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            KKIN+  F+D    + L  A    +  ++   +   +    ++   N G   LH A  QG  + +KL+++ G A VNIP+ +     PLH+AA +G  D+++ L++H +NP MV  S  T +D+A  + +  + +LL  +N
Sbjct:   38 KKINVN-FQDPDGFSALHHAALNGNTELISLLL---EAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNIPSDEGH--IPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSN 171          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A [Source:HGNC Symbol;Acc:HGNC:20961])

HSP 1 Score: 65.855 bits (159), Expect = 1.310e-10
Identity = 36/114 (31.58%), Postives = 60/114 (52.63%), Query Frame = 3
Query: 1131 VVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            VV+  + N     + N   + G   LHLA  +G+   V+LLI  G +   +   + D+ T LH AA YG  ++ + L+E   +P+M      T +D+A LY + E+ K+L +A+
Sbjct:   95 VVEVLLRN---DALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAH 205          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: TNKS (tankyrase [Source:HGNC Symbol;Acc:HGNC:11941])

HSP 1 Score: 64.6994 bits (156), Expect = 3.122e-10
Identity = 48/142 (33.80%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LP+
Sbjct:  831 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPT 963          

HSP 2 Score: 56.9954 bits (136), Expect = 8.682e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  648 SDVDY-RLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789          

HSP 3 Score: 52.373 bits (124), Expect = 2.134e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  366 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRE 482          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: TNKS (tankyrase [Source:HGNC Symbol;Acc:HGNC:11941])

HSP 1 Score: 64.6994 bits (156), Expect = 3.122e-10
Identity = 48/142 (33.80%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LP+
Sbjct:  831 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPT 963          

HSP 2 Score: 56.9954 bits (136), Expect = 8.682e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  648 SDVDY-RLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789          

HSP 3 Score: 52.373 bits (124), Expect = 2.134e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  366 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRE 482          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: TNKS (tankyrase [Source:HGNC Symbol;Acc:HGNC:11941])

HSP 1 Score: 64.6994 bits (156), Expect = 3.122e-10
Identity = 48/142 (33.80%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LP+
Sbjct:  831 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPT 963          

HSP 2 Score: 56.9954 bits (136), Expect = 8.682e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  648 SDVDY-RLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789          

HSP 3 Score: 52.373 bits (124), Expect = 2.134e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  366 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRE 482          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.254e-9
Identity = 38/121 (31.40%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L LA   N   VV+  + N      ++  +    + LH+A   GN D V LL++ G    N   T  D+ +PLH+AA  GQ+++A  L++H A+ +++T    T + +A+ Y   E+ +LL
Sbjct:  462 LHLAARANQTDVVRVLIRN---GAKVDAQARELQTPLHIASRLGNTDIVILLLQAG---ANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLL 576          

HSP 2 Score: 56.9954 bits (136), Expect = 3.191e-8
Identity = 38/115 (33.04%), Postives = 69/115 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLL-HDANHVQQLPSESISS 1508
            ++  +  GN+ALH+A   G    V +L+ENG A+VN+ + +    TPL+MAA    +++ + L++HGAN ++ T    T + +A L + H+  +A LL +D+    +LP+  I++
Sbjct:   92 VDAATRKGNTALHIASLAGQSLIVTILVENG-ANVNVQSVN--GFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVA-LQQGHDRVVAVLLENDSKGKVRLPALHIAA 202          

HSP 3 Score: 56.6102 bits (135), Expect = 3.789e-8
Identity = 42/128 (32.81%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVN---NYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            L +A    ++++V Y +    N DV T+       G + LHLA      D V++LI NG A V+    +    TPLH+A+  G  DI   L++ GAN +  T  N + + +A    Q E+A +L D N
Sbjct:  429 LHVAAFMGAINIVIYLLQQGANPDVETV------RGETPLHLAARANQTDVVRVLIRNG-AKVDAQARELQ--TPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHN 547          

HSP 4 Score: 56.225 bits (134), Expect = 5.817e-8
Identity = 37/107 (34.58%), Postives = 55/107 (51.40%), Query Frame = 3
Query: 1104 LAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            L    + + V Q   NN      IN  +N+G + LH+A   G ++ VK L+ENG ADV          TPLH AA  G  +  + L+E+GA+P+  T +  T + +A
Sbjct:  695 LCAQEDHVPVAQILYNN---GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENG-ADVG--EKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795          

HSP 5 Score: 53.9138 bits (128), Expect = 3.286e-7
Identity = 33/93 (35.48%), Postives = 50/93 (53.76%), Query Frame = 3
Query: 1182 VSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ++  G + LHLA   GN++ V+LL+E G   V+I   +    TPLH+AA Y    +A  L+E+GA+      +  T + +A    Q EIA  L
Sbjct:  553 LTKKGFTPLHLASKYGNLEVVRLLLERG-TPVDIEGKN--QVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTL 642          

HSP 6 Score: 51.6026 bits (122), Expect = 1.433e-6
Identity = 30/86 (34.88%), Postives = 47/86 (54.65%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ALH+A  + +  A  LL++N H   N   T     TPLH+AA YG +++ Q L+E GAN +     N + + +A  + +  +A LL
Sbjct:  197 ALHIAAKKDDTTAATLLLQNEH---NPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLL 279          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.254e-9
Identity = 38/121 (31.40%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L LA   N   VV+  + N      ++  +    + LH+A   GN D V LL++ G    N   T  D+ +PLH+AA  GQ+++A  L++H A+ +++T    T + +A+ Y   E+ +LL
Sbjct:  462 LHLAARANQTDVVRVLIRN---GAKVDAQARELQTPLHIASRLGNTDIVILLLQAG---ANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLL 576          

HSP 2 Score: 56.9954 bits (136), Expect = 3.191e-8
Identity = 38/115 (33.04%), Postives = 69/115 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLL-HDANHVQQLPSESISS 1508
            ++  +  GN+ALH+A   G    V +L+ENG A+VN+ + +    TPL+MAA    +++ + L++HGAN ++ T    T + +A L + H+  +A LL +D+    +LP+  I++
Sbjct:   92 VDAATRKGNTALHIASLAGQSLIVTILVENG-ANVNVQSVN--GFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVA-LQQGHDRVVAVLLENDSKGKVRLPALHIAA 202          

HSP 3 Score: 56.6102 bits (135), Expect = 3.789e-8
Identity = 42/128 (32.81%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVN---NYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            L +A    ++++V Y +    N DV T+       G + LHLA      D V++LI NG A V+    +    TPLH+A+  G  DI   L++ GAN +  T  N + + +A    Q E+A +L D N
Sbjct:  429 LHVAAFMGAINIVIYLLQQGANPDVETV------RGETPLHLAARANQTDVVRVLIRNG-AKVDAQARELQ--TPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHN 547          

HSP 4 Score: 56.225 bits (134), Expect = 5.817e-8
Identity = 37/107 (34.58%), Postives = 55/107 (51.40%), Query Frame = 3
Query: 1104 LAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            L    + + V Q   NN      IN  +N+G + LH+A   G ++ VK L+ENG ADV          TPLH AA  G  +  + L+E+GA+P+  T +  T + +A
Sbjct:  695 LCAQEDHVPVAQILYNN---GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENG-ADVG--EKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795          

HSP 5 Score: 53.9138 bits (128), Expect = 3.286e-7
Identity = 33/93 (35.48%), Postives = 50/93 (53.76%), Query Frame = 3
Query: 1182 VSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ++  G + LHLA   GN++ V+LL+E G   V+I   +    TPLH+AA Y    +A  L+E+GA+      +  T + +A    Q EIA  L
Sbjct:  553 LTKKGFTPLHLASKYGNLEVVRLLLERG-TPVDIEGKN--QVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTL 642          

HSP 6 Score: 51.6026 bits (122), Expect = 1.433e-6
Identity = 30/86 (34.88%), Postives = 47/86 (54.65%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ALH+A  + +  A  LL++N H   N   T     TPLH+AA YG +++ Q L+E GAN +     N + + +A  + +  +A LL
Sbjct:  197 ALHIAAKKDDTTAATLLLQNEH---NPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLL 279          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.261e-9
Identity = 38/121 (31.40%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L LA   N   VV+  + N      ++  +    + LH+A   GN D V LL++ G    N   T  D+ +PLH+AA  GQ+++A  L++H A+ +++T    T + +A+ Y   E+ +LL
Sbjct:  462 LHLAARANQTDVVRVLIRN---GAKVDAQARELQTPLHIASRLGNTDIVILLLQAG---ANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLL 576          

HSP 2 Score: 56.9954 bits (136), Expect = 3.198e-8
Identity = 38/115 (33.04%), Postives = 69/115 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLL-HDANHVQQLPSESISS 1508
            ++  +  GN+ALH+A   G    V +L+ENG A+VN+ + +    TPL+MAA    +++ + L++HGAN ++ T    T + +A L + H+  +A LL +D+    +LP+  I++
Sbjct:   92 VDAATRKGNTALHIASLAGQSLIVTILVENG-ANVNVQSVN--GFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVA-LQQGHDRVVAVLLENDSKGKVRLPALHIAA 202          

HSP 3 Score: 56.6102 bits (135), Expect = 3.796e-8
Identity = 42/128 (32.81%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVN---NYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            L +A    ++++V Y +    N DV T+       G + LHLA      D V++LI NG A V+    +    TPLH+A+  G  DI   L++ GAN +  T  N + + +A    Q E+A +L D N
Sbjct:  429 LHVAAFMGAINIVIYLLQQGANPDVETV------RGETPLHLAARANQTDVVRVLIRNG-AKVDAQARELQ--TPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHN 547          

HSP 4 Score: 56.225 bits (134), Expect = 5.828e-8
Identity = 37/107 (34.58%), Postives = 55/107 (51.40%), Query Frame = 3
Query: 1104 LAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            L    + + V Q   NN      IN  +N+G + LH+A   G ++ VK L+ENG ADV          TPLH AA  G  +  + L+E+GA+P+  T +  T + +A
Sbjct:  695 LCAQEDHVPVAQILYNN---GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENG-ADVG--EKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795          

HSP 5 Score: 53.9138 bits (128), Expect = 3.291e-7
Identity = 33/93 (35.48%), Postives = 50/93 (53.76%), Query Frame = 3
Query: 1182 VSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ++  G + LHLA   GN++ V+LL+E G   V+I   +    TPLH+AA Y    +A  L+E+GA+      +  T + +A    Q EIA  L
Sbjct:  553 LTKKGFTPLHLASKYGNLEVVRLLLERG-TPVDIEGKN--QVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTL 642          

HSP 6 Score: 51.6026 bits (122), Expect = 1.436e-6
Identity = 30/86 (34.88%), Postives = 47/86 (54.65%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ALH+A  + +  A  LL++N H   N   T     TPLH+AA YG +++ Q L+E GAN +     N + + +A  + +  +A LL
Sbjct:  197 ALHIAAKKDDTTAATLLLQNEH---NPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLL 279          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.261e-9
Identity = 38/121 (31.40%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L LA   N   VV+  + N      ++  +    + LH+A   GN D V LL++ G    N   T  D+ +PLH+AA  GQ+++A  L++H A+ +++T    T + +A+ Y   E+ +LL
Sbjct:  462 LHLAARANQTDVVRVLIRN---GAKVDAQARELQTPLHIASRLGNTDIVILLLQAG---ANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLL 576          

HSP 2 Score: 56.9954 bits (136), Expect = 3.198e-8
Identity = 38/115 (33.04%), Postives = 69/115 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLL-HDANHVQQLPSESISS 1508
            ++  +  GN+ALH+A   G    V +L+ENG A+VN+ + +    TPL+MAA    +++ + L++HGAN ++ T    T + +A L + H+  +A LL +D+    +LP+  I++
Sbjct:   92 VDAATRKGNTALHIASLAGQSLIVTILVENG-ANVNVQSVN--GFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVA-LQQGHDRVVAVLLENDSKGKVRLPALHIAA 202          

HSP 3 Score: 56.6102 bits (135), Expect = 3.796e-8
Identity = 42/128 (32.81%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVN---NYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            L +A    ++++V Y +    N DV T+       G + LHLA      D V++LI NG A V+    +    TPLH+A+  G  DI   L++ GAN +  T  N + + +A    Q E+A +L D N
Sbjct:  429 LHVAAFMGAINIVIYLLQQGANPDVETV------RGETPLHLAARANQTDVVRVLIRNG-AKVDAQARELQ--TPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHN 547          

HSP 4 Score: 56.225 bits (134), Expect = 5.828e-8
Identity = 37/107 (34.58%), Postives = 55/107 (51.40%), Query Frame = 3
Query: 1104 LAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            L    + + V Q   NN      IN  +N+G + LH+A   G ++ VK L+ENG ADV          TPLH AA  G  +  + L+E+GA+P+  T +  T + +A
Sbjct:  695 LCAQEDHVPVAQILYNN---GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENG-ADVG--EKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795          

HSP 5 Score: 53.9138 bits (128), Expect = 3.291e-7
Identity = 33/93 (35.48%), Postives = 50/93 (53.76%), Query Frame = 3
Query: 1182 VSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ++  G + LHLA   GN++ V+LL+E G   V+I   +    TPLH+AA Y    +A  L+E+GA+      +  T + +A    Q EIA  L
Sbjct:  553 LTKKGFTPLHLASKYGNLEVVRLLLERG-TPVDIEGKN--QVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTL 642          

HSP 6 Score: 51.6026 bits (122), Expect = 1.436e-6
Identity = 30/86 (34.88%), Postives = 47/86 (54.65%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ALH+A  + +  A  LL++N H   N   T     TPLH+AA YG +++ Q L+E GAN +     N + + +A  + +  +A LL
Sbjct:  197 ALHIAAKKDDTTAATLLLQNEH---NPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLL 279          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.267e-9
Identity = 38/121 (31.40%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L LA   N   VV+  + N      ++  +    + LH+A   GN D V LL++ G    N   T  D+ +PLH+AA  GQ+++A  L++H A+ +++T    T + +A+ Y   E+ +LL
Sbjct:  462 LHLAARANQTDVVRVLIRN---GAKVDAQARELQTPLHIASRLGNTDIVILLLQAG---ANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLL 576          

HSP 2 Score: 56.9954 bits (136), Expect = 3.203e-8
Identity = 38/115 (33.04%), Postives = 69/115 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLL-HDANHVQQLPSESISS 1508
            ++  +  GN+ALH+A   G    V +L+ENG A+VN+ + +    TPL+MAA    +++ + L++HGAN ++ T    T + +A L + H+  +A LL +D+    +LP+  I++
Sbjct:   92 VDAATRKGNTALHIASLAGQSLIVTILVENG-ANVNVQSVN--GFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVA-LQQGHDRVVAVLLENDSKGKVRLPALHIAA 202          

HSP 3 Score: 56.6102 bits (135), Expect = 3.803e-8
Identity = 42/128 (32.81%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVN---NYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            L +A    ++++V Y +    N DV T+       G + LHLA      D V++LI NG A V+    +    TPLH+A+  G  DI   L++ GAN +  T  N + + +A    Q E+A +L D N
Sbjct:  429 LHVAAFMGAINIVIYLLQQGANPDVETV------RGETPLHLAARANQTDVVRVLIRNG-AKVDAQARELQ--TPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHN 547          

HSP 4 Score: 56.225 bits (134), Expect = 5.838e-8
Identity = 37/107 (34.58%), Postives = 55/107 (51.40%), Query Frame = 3
Query: 1104 LAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            L    + + V Q   NN      IN  +N+G + LH+A   G ++ VK L+ENG ADV          TPLH AA  G  +  + L+E+GA+P+  T +  T + +A
Sbjct:  695 LCAQEDHVPVAQILYNN---GAEINSKTNAGYTPLHVACHFGQLNMVKFLVENG-ADVG--EKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795          

HSP 5 Score: 53.9138 bits (128), Expect = 3.297e-7
Identity = 33/93 (35.48%), Postives = 50/93 (53.76%), Query Frame = 3
Query: 1182 VSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ++  G + LHLA   GN++ V+LL+E G   V+I   +    TPLH+AA Y    +A  L+E+GA+      +  T + +A    Q EIA  L
Sbjct:  553 LTKKGFTPLHLASKYGNLEVVRLLLERG-TPVDIEGKN--QVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTL 642          

HSP 6 Score: 51.6026 bits (122), Expect = 1.438e-6
Identity = 30/86 (34.88%), Postives = 47/86 (54.65%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ALH+A  + +  A  LL++N H   N   T     TPLH+AA YG +++ Q L+E GAN +     N + + +A  + +  +A LL
Sbjct:  197 ALHIAAKKDDTTAATLLLQNEH---NPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLL 279          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: nompC (gene:FBgn0016920 transcript:FBtr0347408)

HSP 1 Score: 63.5438 bits (153), Expect = 4.140e-10
Identity = 69/238 (28.99%), Postives = 103/238 (43.28%), Query Frame = 3
Query:  810 VKFSTQNKHLIKILLTIRALALVSIWTSVIN--FYRNLIGRGDVQLKSIEIHLPD--------QSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            VK    +K ++++LL   A   +   T++     Y  + G  DV ++ I    P         QS V ++ + +A CH+    L   +      +  F D + R+ L LA     L V    + N      IN  S  G +ALHLA   G    VK LI++ +A ++I        TPLH+AA  GQ ++ Q L+E GAN           I +A      E+AKL      +QQ PS
Sbjct:  593 VKIPESDKQIVRMLLENGADVTLQTKTALETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIA-CHRGHMELVNNLLANHARVDVF-DTEGRSALHLAAERGYLHVCDALLTN---KAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDI--LTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLF-----LQQHPS 818          

HSP 2 Score: 54.299 bits (129), Expect = 2.922e-7
Identity = 41/145 (28.28%), Postives = 68/145 (46.90%), Query Frame = 3
Query: 1041 INKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANH 1475
            +N   + +     E   N L LA     +SVV   ++    + ++     +G + LH+A   G+I  V++L+  G A++N   TD +  TPLH AA  G  ++ + L E GA+P   T     AI  A     +E+ + L +  H
Sbjct:  995 LNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSR--SAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQG-AEINA--TDRNGWTPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAASEGHNEVLRYLMNKEH 1134          

HSP 3 Score: 52.7582 bits (125), Expect = 7.308e-7
Identity = 32/135 (23.70%), Postives = 64/135 (47.41%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQ 1481
            D+  +  + +A   N   V + F+  +   +++N  S  GN+  H+A  QG++  ++ L++   + V        D TPL +AA  G  D+ + LV  GA+ +    +  TA+ +A      ++  +L   N ++
Sbjct:  790 DDLGQKPIHVAAQNNYSEVAKLFLQQH--PSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNSLR 922          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: nompC (gene:FBgn0016920 transcript:FBtr0300012)

HSP 1 Score: 63.5438 bits (153), Expect = 4.165e-10
Identity = 69/238 (28.99%), Postives = 103/238 (43.28%), Query Frame = 3
Query:  810 VKFSTQNKHLIKILLTIRALALVSIWTSVIN--FYRNLIGRGDVQLKSIEIHLPD--------QSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            VK    +K ++++LL   A   +   T++     Y  + G  DV ++ I    P         QS V ++ + +A CH+    L   +      +  F D + R+ L LA     L V    + N      IN  S  G +ALHLA   G    VK LI++ +A ++I        TPLH+AA  GQ ++ Q L+E GAN           I +A      E+AKL      +QQ PS
Sbjct:  593 VKIPESDKQIVRMLLENGADVTLQTKTALETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIA-CHRGHMELVNNLLANHARVDVF-DTEGRSALHLAAERGYLHVCDALLTN---KAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDI--LTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLF-----LQQHPS 818          

HSP 2 Score: 54.299 bits (129), Expect = 2.940e-7
Identity = 41/145 (28.28%), Postives = 68/145 (46.90%), Query Frame = 3
Query: 1041 INKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANH 1475
            +N   + +     E   N L LA     +SVV   ++    + ++     +G + LH+A   G+I  V++L+  G A++N   TD +  TPLH AA  G  ++ + L E GA+P   T     AI  A     +E+ + L +  H
Sbjct:  995 LNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSR--SAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQG-AEINA--TDRNGWTPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAASEGHNEVLRYLMNKEH 1134          

HSP 3 Score: 52.7582 bits (125), Expect = 7.355e-7
Identity = 32/135 (23.70%), Postives = 64/135 (47.41%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQ 1481
            D+  +  + +A   N   V + F+  +   +++N  S  GN+  H+A  QG++  ++ L++   + V        D TPL +AA  G  D+ + LV  GA+ +    +  TA+ +A      ++  +L   N ++
Sbjct:  790 DDLGQKPIHVAAQNNYSEVAKLFLQQH--PSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNSLR 922          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: nompC (gene:FBgn0016920 transcript:FBtr0347409)

HSP 1 Score: 63.1586 bits (152), Expect = 4.514e-10
Identity = 69/238 (28.99%), Postives = 103/238 (43.28%), Query Frame = 3
Query:  810 VKFSTQNKHLIKILLTIRALALVSIWTSVIN--FYRNLIGRGDVQLKSIEIHLPD--------QSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            VK    +K ++++LL   A   +   T++     Y  + G  DV ++ I    P         QS V ++ + +A CH+    L   +      +  F D + R+ L LA     L V    + N      IN  S  G +ALHLA   G    VK LI++ +A ++I        TPLH+AA  GQ ++ Q L+E GAN           I +A      E+AKL      +QQ PS
Sbjct:  593 VKIPESDKQIVRMLLENGADVTLQTKTALETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIA-CHRGHMELVNNLLANHARVDVF-DTEGRSALHLAAERGYLHVCDALLTN---KAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDI--LTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLF-----LQQHPS 818          

HSP 2 Score: 54.299 bits (129), Expect = 3.157e-7
Identity = 41/145 (28.28%), Postives = 68/145 (46.90%), Query Frame = 3
Query: 1041 INKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANH 1475
            +N   + +     E   N L LA     +SVV   ++    + ++     +G + LH+A   G+I  V++L+  G A++N   TD +  TPLH AA  G  ++ + L E GA+P   T     AI  A     +E+ + L +  H
Sbjct:  995 LNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSR--SAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQG-AEINA--TDRNGWTPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAASEGHNEVLRYLMNKEH 1134          

HSP 3 Score: 52.7582 bits (125), Expect = 7.763e-7
Identity = 32/135 (23.70%), Postives = 64/135 (47.41%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQ 1481
            D+  +  + +A   N   V + F+  +   +++N  S  GN+  H+A  QG++  ++ L++   + V        D TPL +AA  G  D+ + LV  GA+ +    +  TA+ +A      ++  +L   N ++
Sbjct:  790 DDLGQKPIHVAAQNNYSEVAKLFLQQH--PSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNSLR 922          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: nompC (gene:FBgn0016920 transcript:FBtr0343224)

HSP 1 Score: 63.1586 bits (152), Expect = 5.036e-10
Identity = 69/238 (28.99%), Postives = 103/238 (43.28%), Query Frame = 3
Query:  810 VKFSTQNKHLIKILLTIRALALVSIWTSVIN--FYRNLIGRGDVQLKSIEIHLPD--------QSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            VK    +K ++++LL   A   +   T++     Y  + G  DV ++ I    P         QS V ++ + +A CH+    L   +      +  F D + R+ L LA     L V    + N      IN  S  G +ALHLA   G    VK LI++ +A ++I        TPLH+AA  GQ ++ Q L+E GAN           I +A      E+AKL      +QQ PS
Sbjct:  593 VKIPESDKQIVRMLLENGADVTLQTKTALETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIA-CHRGHMELVNNLLANHARVDVF-DTEGRSALHLAAERGYLHVCDALLTN---KAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDI--LTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLF-----LQQHPS 818          

HSP 2 Score: 53.9138 bits (128), Expect = 3.404e-7
Identity = 41/145 (28.28%), Postives = 68/145 (46.90%), Query Frame = 3
Query: 1041 INKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANH 1475
            +N   + +     E   N L LA     +SVV   ++    + ++     +G + LH+A   G+I  V++L+  G A++N   TD +  TPLH AA  G  ++ + L E GA+P   T     AI  A     +E+ + L +  H
Sbjct:  995 LNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSR--SAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQG-AEINA--TDRNGWTPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAASEGHNEVLRYLMNKEH 1134          

HSP 3 Score: 52.7582 bits (125), Expect = 8.587e-7
Identity = 32/135 (23.70%), Postives = 64/135 (47.41%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQ 1481
            D+  +  + +A   N   V + F+  +   +++N  S  GN+  H+A  QG++  ++ L++   + V        D TPL +AA  G  D+ + LV  GA+ +    +  TA+ +A      ++  +L   N ++
Sbjct:  790 DDLGQKPIHVAAQNNYSEVAKLFLQQH--PSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNSLR 922          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: nompC (gene:FBgn0016920 transcript:FBtr0304843)

HSP 1 Score: 63.1586 bits (152), Expect = 5.347e-10
Identity = 69/238 (28.99%), Postives = 103/238 (43.28%), Query Frame = 3
Query:  810 VKFSTQNKHLIKILLTIRALALVSIWTSVIN--FYRNLIGRGDVQLKSIEIHLPD--------QSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            VK    +K ++++LL   A   +   T++     Y  + G  DV ++ I    P         QS V ++ + +A CH+    L   +      +  F D + R+ L LA     L V    + N      IN  S  G +ALHLA   G    VK LI++ +A ++I        TPLH+AA  GQ ++ Q L+E GAN           I +A      E+AKL      +QQ PS
Sbjct:  593 VKIPESDKQIVRMLLENGADVTLQTKTALETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIA-CHRGHMELVNNLLANHARVDVF-DTEGRSALHLAAERGYLHVCDALLTN---KAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDI--LTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLF-----LQQHPS 818          

HSP 2 Score: 53.9138 bits (128), Expect = 3.433e-7
Identity = 41/145 (28.28%), Postives = 68/145 (46.90%), Query Frame = 3
Query: 1041 INKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANH 1475
            +N   + +     E   N L LA     +SVV   ++    + ++     +G + LH+A   G+I  V++L+  G A++N   TD +  TPLH AA  G  ++ + L E GA+P   T     AI  A     +E+ + L +  H
Sbjct:  995 LNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSR--SAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQG-AEINA--TDRNGWTPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAASEGHNEVLRYLMNKEH 1134          

HSP 3 Score: 52.7582 bits (125), Expect = 8.885e-7
Identity = 32/135 (23.70%), Postives = 64/135 (47.41%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQ 1481
            D+  +  + +A   N   V + F+  +   +++N  S  GN+  H+A  QG++  ++ L++   + V        D TPL +AA  G  D+ + LV  GA+ +    +  TA+ +A      ++  +L   N ++
Sbjct:  790 DDLGQKPIHVAAQNNYSEVAKLFLQQH--PSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNSLR 922          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tnksa (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a [Source:ZFIN;Acc:ZDB-GENE-030131-7450])

HSP 1 Score: 65.855 bits (159), Expect = 9.169e-11
Identity = 49/142 (34.51%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LPS
Sbjct:  756 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPS 888          

HSP 2 Score: 56.9954 bits (136), Expect = 4.758e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +DM
Sbjct:  573 SDVDY-RLLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDM 714          

HSP 3 Score: 52.373 bits (124), Expect = 1.541e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  291 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 407          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tnksa (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a [Source:ZFIN;Acc:ZDB-GENE-030131-7450])

HSP 1 Score: 65.855 bits (159), Expect = 9.169e-11
Identity = 49/142 (34.51%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LPS
Sbjct:  756 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPS 888          

HSP 2 Score: 56.9954 bits (136), Expect = 4.758e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +DM
Sbjct:  573 SDVDY-RLLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDM 714          

HSP 3 Score: 52.373 bits (124), Expect = 1.541e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  291 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 407          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tnksa (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a [Source:ZFIN;Acc:ZDB-GENE-030131-7450])

HSP 1 Score: 65.855 bits (159), Expect = 9.169e-11
Identity = 49/142 (34.51%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LPS
Sbjct:  756 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPS 888          

HSP 2 Score: 56.9954 bits (136), Expect = 4.758e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +DM
Sbjct:  573 SDVDY-RLLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDM 714          

HSP 3 Score: 52.373 bits (124), Expect = 1.541e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  291 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 407          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tnksa (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a [Source:ZFIN;Acc:ZDB-GENE-030131-7450])

HSP 1 Score: 65.855 bits (159), Expect = 9.220e-11
Identity = 49/142 (34.51%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LPS
Sbjct:  784 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPS 916          

HSP 2 Score: 56.9954 bits (136), Expect = 4.780e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +DM
Sbjct:  601 SDVDY-RLLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDM 742          

HSP 3 Score: 51.9878 bits (123), Expect = 1.934e-6
Identity = 37/116 (31.90%), Postives = 58/116 (50.00%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  326 LHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 435          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tnksb (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b [Source:NCBI gene;Acc:567533])

HSP 1 Score: 65.855 bits (159), Expect = 9.585e-11
Identity = 51/142 (35.92%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRN--LLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGANP+M      TA+D+A      +I  LL DA     LPS
Sbjct:  763 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---FNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGANPTMKNQEGQTALDLAT---ADDIRALLMDAMPPDALPS 895          

HSP 2 Score: 60.077 bits (144), Expect = 5.134e-9
Identity = 46/153 (30.07%), Postives = 77/153 (50.33%), Query Frame = 3
Query:  963 PDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            P  SDV Y R+  A     + T++   + + +N ++     S   L  A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+PS      + A+DM
Sbjct:  577 PRNSDVDY-RLLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHS-TPLHFAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPSKKNRDGNMALDM 721          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: cyp1a1 (cytochrome P450 family 1 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-990173])

HSP 1 Score: 67.3958 bits (163), Expect = 3.887e-11
Identity = 44/112 (39.29%), Postives = 62/112 (55.36%), Query Frame = 3
Query: 1131 VVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENG--HADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            VV+  + N  V+ I +C    G   LHLA  +G+   V+LLI +G  HA VN  N D +  T LH AA YG  D+ + L+E   +P+M      T +D+A LY + E+ KLL
Sbjct:   60 VVEILLRNEAVTNIADC---KGCFPLHLAAWKGDAHIVRLLIHHGPSHAKVNEQNNDNE--TALHCAAQYGHTDVVRVLLEELTDPTMRNNKLETPLDLAALYGRLEVVKLL 166          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: foxj3 (forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185])

HSP 1 Score: 65.0846 bits (157), Expect = 2.037e-10
Identity = 48/142 (33.80%), Postives = 69/142 (48.59%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M    + T +D+A      +I  LL DA   + LP+
Sbjct:  734 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQESQTPLDLAT---ADDIRALLIDAMPPEALPT 866          

HSP 2 Score: 56.6102 bits (135), Expect = 8.667e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  551 SDVDY-RLLEASKAGDLDTVKQLCSSQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 692          

HSP 3 Score: 52.7582 bits (125), Expect = 1.553e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  269 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHFEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 385          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: foxj3 (forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185])

HSP 1 Score: 65.0846 bits (157), Expect = 2.040e-10
Identity = 48/142 (33.80%), Postives = 69/142 (48.59%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M    + T +D+A      +I  LL DA   + LP+
Sbjct:  741 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQESQTPLDLAT---ADDIRALLIDAMPPEALPT 873          

HSP 2 Score: 56.6102 bits (135), Expect = 8.678e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  558 SDVDY-RLLEASKAGDLDTVKQLCSSQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 699          

HSP 3 Score: 52.7582 bits (125), Expect = 1.555e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  276 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHFEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 392          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: foxj3 (forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185])

HSP 1 Score: 65.0846 bits (157), Expect = 2.044e-10
Identity = 48/142 (33.80%), Postives = 69/142 (48.59%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M    + T +D+A      +I  LL DA   + LP+
Sbjct:  745 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQESQTPLDLAT---ADDIRALLIDAMPPEALPT 877          

HSP 2 Score: 56.6102 bits (135), Expect = 8.691e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  562 SDVDY-RLLEASKAGDLDTVKQLCSSQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 703          

HSP 3 Score: 52.373 bits (124), Expect = 1.946e-6
Identity = 37/116 (31.90%), Postives = 58/116 (50.00%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  287 LHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHFEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 396          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: foxj3 (forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185])

HSP 1 Score: 65.0846 bits (157), Expect = 2.049e-10
Identity = 48/142 (33.80%), Postives = 69/142 (48.59%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M    + T +D+A      +I  LL DA   + LP+
Sbjct:  763 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQESQTPLDLAT---ADDIRALLIDAMPPEALPT 895          

HSP 2 Score: 56.6102 bits (135), Expect = 8.709e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  580 SDVDY-RLLEASKAGDLDTVKQLCSSQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 721          

HSP 3 Score: 52.7582 bits (125), Expect = 1.560e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  298 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHFEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKE 414          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Anks1 (ankyrin repeat and SAM domain containing 1 [Source:MGI Symbol;Acc:MGI:2446180])

HSP 1 Score: 66.6254 bits (161), Expect = 5.490e-11
Identity = 37/114 (32.46%), Postives = 60/114 (52.63%), Query Frame = 3
Query: 1131 VVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            VV+  + N     + N   + G   LHLA  +G+   V+LLI+ G +   +   + D+ T LH AA YG  ++ + L+E   +P+M      T +D+A LY + E+ KLL  A+
Sbjct:   91 VVEVLLRN---DALTNVADSKGCYPLHLAAWKGDAQIVRLLIQQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLGAH 201          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Anks1 (ankyrin repeat and SAM domain containing 1 [Source:MGI Symbol;Acc:MGI:2446180])

HSP 1 Score: 66.6254 bits (161), Expect = 5.543e-11
Identity = 37/114 (32.46%), Postives = 60/114 (52.63%), Query Frame = 3
Query: 1131 VVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            VV+  + N     + N   + G   LHLA  +G+   V+LLI+ G +   +   + D+ T LH AA YG  ++ + L+E   +P+M      T +D+A LY + E+ KLL  A+
Sbjct:   91 VVEVLLRN---DALTNVADSKGCYPLHLAAWKGDAQIVRLLIQQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLGAH 201          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Caskin1 (CASK interacting protein 1 [Source:MGI Symbol;Acc:MGI:2442952])

HSP 1 Score: 65.855 bits (159), Expect = 9.835e-11
Identity = 42/141 (29.79%), Postives = 75/141 (53.19%), Query Frame = 3
Query: 1050 KKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            KKIN+  F+D    + L  A    +  ++   +   +    ++   N G   LH A  QG  + +KL+++ G A VN+P+ +     PLH+AA +G  D+++ L++H +NP MV  S  T +D+A  + +  + +LL  +N
Sbjct:   38 KKINVN-FQDPDGFSALHHAALNGNTELISLLL---EAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNVPSDEGH--IPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSN 171          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Caskin1 (CASK interacting protein 1 [Source:MGI Symbol;Acc:MGI:2442952])

HSP 1 Score: 65.855 bits (159), Expect = 9.946e-11
Identity = 42/141 (29.79%), Postives = 75/141 (53.19%), Query Frame = 3
Query: 1050 KKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            KKIN+  F+D    + L  A    +  ++   +   +    ++   N G   LH A  QG  + +KL+++ G A VN+P+ +     PLH+AA +G  D+++ L++H +NP MV  S  T +D+A  + +  + +LL  +N
Sbjct:   38 KKINVN-FQDPDGFSALHHAALNGNTELISLLL---EAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNVPSDEGH--IPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSN 171          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Tnks (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase [Source:MGI Symbol;Acc:MGI:1341087])

HSP 1 Score: 64.6994 bits (156), Expect = 2.141e-10
Identity = 48/142 (33.80%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LP+
Sbjct:  824 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPT 956          

HSP 2 Score: 56.6102 bits (135), Expect = 7.574e-8
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  641 SDVDY-RLLEASKAGDLETVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 782          

HSP 3 Score: 52.373 bits (124), Expect = 1.464e-6
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P++V     +A+DMA   E  E
Sbjct:  359 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRE 475          
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|P40480|HOS4_YEAST (Protein HOS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HOS4 PE=1 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 2.782e-11
Identity = 45/118 (38.14%), Postives = 66/118 (55.93%), Query Frame = 3
Query: 1071 FRDEQSRNLLILAVSYNSLSVVQYFV--NNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAID 1418
            +RD   R  L +A       VV+  +    YD    IN   N+GN+ALH A  QG+I+ V+LLIENG ADVNI + +    TPL  A+  G  D+ + L+++GA+P++      TA +
Sbjct:  325 YRDSGGRTRLQIACDKGKYDVVKKMIEEGGYD----INDQDNAGNTALHEAALQGHIEIVELLIENG-ADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFE 437          
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8WXD9|CSKI1_HUMAN (Caskin-1 OS=Homo sapiens OX=9606 GN=CASKIN1 PE=1 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 4.482e-10
Identity = 43/141 (30.50%), Postives = 75/141 (53.19%), Query Frame = 3
Query: 1050 KKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            KKIN+  F+D    + L  A    +  ++   +   +    ++   N G   LH A  QG  + +KL+++ G A VNIP+ +     PLH+AA +G  D+++ L++H +NP MV  S  T +D+A  + +  + +LL  +N
Sbjct:   38 KKINVN-FQDPDGFSALHHAALNGNTELISLLL---EAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNIPSDEGH--IPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSN 171          
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q92625|ANS1A_HUMAN (Ankyrin repeat and SAM domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ANKS1A PE=1 SV=4)

HSP 1 Score: 65.855 bits (159), Expect = 6.291e-10
Identity = 36/114 (31.58%), Postives = 60/114 (52.63%), Query Frame = 3
Query: 1131 VVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            VV+  + N     + N   + G   LHLA  +G+   V+LLI  G +   +   + D+ T LH AA YG  ++ + L+E   +P+M      T +D+A LY + E+ K+L +A+
Sbjct:   95 VVEVLLRN---DALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAH 205          
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6P9K8|CSKI1_MOUSE (Caskin-1 OS=Mus musculus OX=10090 GN=Caskin1 PE=1 SV=2)

HSP 1 Score: 65.855 bits (159), Expect = 6.957e-10
Identity = 42/141 (29.79%), Postives = 75/141 (53.19%), Query Frame = 3
Query: 1050 KKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDAN 1472
            KKIN+  F+D    + L  A    +  ++   +   +    ++   N G   LH A  QG  + +KL+++ G A VN+P+ +     PLH+AA +G  D+++ L++H +NP MV  S  T +D+A  + +  + +LL  +N
Sbjct:   38 KKINVN-FQDPDGFSALHHAALNGNTELISLLL---EAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNVPSDEGH--IPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSN 171          
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6PFX9|TNKS1_MOUSE (Poly [ADP-ribose] polymerase tankyrase-1 OS=Mus musculus OX=10090 GN=Tnks PE=1 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 1.497e-9
Identity = 48/142 (33.80%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA   + LP+
Sbjct:  824 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPEALPT 956          

HSP 2 Score: 56.6102 bits (135), Expect = 5.298e-7
Identity = 44/150 (29.33%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++   + + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  641 SDVDY-RLLEASKAGDLETVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 782          
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A267ENP0 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029695g1 PE=4 SV=1)

HSP 1 Score: 222.631 bits (566), Expect = 5.617e-63
Identity = 132/464 (28.45%), Postives = 230/464 (49.57%), Query Frame = 3
Query:  147 MSRGIRDLREIICVSRLCNVYQNEDILNISDQYLGECVNNNHQFPKPV---DKILNTKHVDKS-------------NGKSLYKSPQIKAALPNIKNCSNSENLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNS-LADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCES-YKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVS--------YNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            MSRG++DLRE+ICVSRL     +++  +  D       ++N  +   +   D +L+ +H                    +     +    LP ++  S               +   ++  L +AN QL +L  W   ++ FV+  +FWL   P   +++LF +E+  L++Q+           + +      +L+L  F E+    +S+ G +  FL+Y D L +    +  + +LT+V+ +T  +   + LL +R+ A+ S+WT+V NFYR L+ RGD +  + E+  P   D +  R+   +   ++  L Y+    K++ + FRD QSRNL+ L+V+           L  ++Y +        ++  S++GNSALHLA   GN+   +LL+++G A+VN+ N  CD CTPLH+A MYG   +   L+EHGA+PS+   +  TA+ +A      +I +LL
Sbjct:    1 MSRGVKDLRELICVSRLAGRGLSDNSADSGDS------DDNEAYAASILRPDTVLSARHPPLPLPPSPPPPPPAPPQAVASSAKARAAKKLPPVQPDS-------LAGLLARADADFIARLLGRANDQLADLSRWCLSDDHFVDLAHFWLTAFPEEAKQDLFRLEHGCLLDQLAFAFKSGTAAAAPVPQSELRRLLLAVFREFPDRLLSARGAHT-FLDYLDTLTAGRSHADCRRLLTDVRLATDVRQHAEWLLALRSFAICSVWTAVANFYRALVDRGDFRPPATEV--PGFGDRLEGRVVRCVQQGYVEVLHYFCLSGKLDPRTFRDGQSRNLIFLSVTCAQRSKENSAQLRTLRYLLKRLQPDPPVDVPSDTGNSALHLAATAGNLQLAELLVQHGRANVNLANALCDSCTPLHLAVMYGHSQLVSYLLEHGADPSLPM-AGQTALQLAEDAGDSDIHELL 447          
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A267FXI5 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018201g4 PE=4 SV=1)

HSP 1 Score: 220.705 bits (561), Expect = 3.304e-62
Identity = 132/463 (28.51%), Postives = 229/463 (49.46%), Query Frame = 3
Query:  147 MSRGIRDLREIICVSRLCNVYQNEDILNISDQYLGECVNNNHQFPKPV---DKILNTKHVDKS------------NGKSLYKSPQIKAALPNIKNCSNSENLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNN-SLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCES-YKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVS--------YNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            MSRG++DLRE+ICVSRL     +++  +  D       ++N  +   +   D +L+ +H                   +     +    LP ++  S               +   ++  L +AN QL +L  W   ++ FV+  +FWL   P   +++LF +E+  L++Q+             +      +L+L  F E+    +S+ G +  FL+Y D L +    +  + +LT+V+ +T  +   + LL +R+ A+ S+WT+V NFYR L+ RGD +  + E+  P   D +  R+   +   ++  L Y+    K++ + FRD QSRNL+ L+V+           L  ++Y +        ++  S++GNSALHLA   GN+   +LL+++G A+VN+ N  CD CTPLH+A MYG   +   L+EHGA+PS+   +  TA+ +A      +I +LL
Sbjct:    1 MSRGVKDLRELICVSRLAGRGLSDNSADSGDS------DDNEAYAASILRPDTVLSARHPPLPLPPSPPPPPAPPQAVASSAKARAAKKLPPVQPDS-------LAGLLARADADFIARLLGRANDQLADLSRWCLSDDHFVDLAHFWLTAFPEEAKQDLFRLEHGCLLDQLAFAFKSGAAAAAPVPQSELRRLLLAVFREFPDRLLSARGAHT-FLDYLDTLTAGRSHADCRRLLTDVRLATDVRQHAEWLLALRSFAICSVWTAVANFYRALVDRGDFRPPATEV--PGFGDRLEGRVVRCVQQGYVEVLHYFCLSGKLDPRTFRDGQSRNLIFLSVTCAQRSKENSAQLRTLRYLLKRLQPDPPVDVPSDTGNSALHLAATAGNLQLAELLVQHGRANVNLANALCDSCTPLHLAVMYGHSQLVSYLLEHGADPSLPM-AGQTALQLAEDAGDSDIHELL 446          
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: K1QYG9 (Caskin-1 OS=Crassostrea gigas OX=29159 GN=CGI_10024140 PE=4 SV=1)

HSP 1 Score: 209.92 bits (533), Expect = 8.879e-58
Identity = 117/357 (32.77%), Postives = 191/357 (53.50%), Query Frame = 3
Query:  390 SNSENLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            S   N  + M Y   I+  ++S WL +ANK +  L ++  +   FV F++FWL + P  Q+ E+F +EYEI+VE+             + ++    LI   F EY    +SS G Y +FL+Y   L S    SYK +L++VK ST+NK   + +L +R+  L+S+W++++NFYRNL            +    +  + + R+  AI   F+  L Y+I    +N   ++D  +R  +  AV YN  SV+ Y +N       +NC +++GN+ LH A   GN++ V +L++N   D+N  N  C+D TPLH+A M G  ++ + L++ GAN  +  G + TA D+A  +   E+  LL
Sbjct:  149 SKGTNFDDMMCY---IDATVVSTWLARANKSVQNLCDFCLNAEKFVQFSHFWLSDFPDQQKNEIFELEYEIIVEEANFAFAVGRDQRKVINRDILSLISAIFREYPGVLLSSKGPY-MFLDYLHVLSSDKQTSYKRLLSDVKCSTRNKQFAQWILAMRSFTLLSVWSAIVNFYRNLKRDVSPGQDRSLLSSSSKESIHHQRVVQAIRLGFVDVLHYYITTALVN-PHYKDSHNRTYIFTAVMYNQPSVLHYLINRVKPPIDVNCPADTGNTPLHAAANNGNVNLVTILLQNPRIDINSKNPQCEDATPLHLAIMLGNDEVVEKLLKMGANVQLKMG-DLTAQDIARDFGHAELLPLL 499          
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A433SL01 (ANK_REP_REGION domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_022442 PE=4 SV=1)

HSP 1 Score: 206.453 bits (524), Expect = 3.950e-56
Identity = 119/404 (29.46%), Postives = 206/404 (50.99%), Query Frame = 3
Query:  264 NNHQFPKPVDKILNTKHVDKSNGKSLYKSPQIKAALPNIKNCSNSENLHE-----FMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
              H+ PKP         V+K  G  + +  ++  A P+ +   +++N        F      ++  +++ WL +AN  + E+  +    + FV F +FWL   P  Q++++F+MEYE L+E++K+       +  +       L    F EY  H +      ++FL+Y D L S     YK +L++V+ +T N+   + LL +R+ ALVS+W SV+NFYRNL G G  Q   I         V   R+  AI   +I  + Y +    ++ Q + D   +  + +AV +N  +V++Y +     +  +N  +++GN+ALH A   GN+  V++L      +VN  N  C++ TPLH++ M+G  +I  CL+EHGA+PS+  G  S    +A  ++ +EI K+L
Sbjct:  137 TRHELPKPTP----LPPVEKIAGTEILREQELLEAKPSYERAKSAKNSKTKTRINFDDMLTYMDATIVANWLTRANNAIEEVTSYCSKGDNFVQFAHFWLSSFPDIQKKDIFSMEYEFLIEELKLAFAVGREDRKIVRGDLVDLCSAVFKEYP-HKLLGGKAPHIFLDYLDILSSEKHVEYKKLLSDVRCATTNRQYAQWLLAVRSFALVSVWASVMNFYRNLTGNGVTQGMPILSLSSSGESVPNRRMLQAIRLGYIDVIHYLLLNGHVSSQ-YSDSHRKTWVFMAVMHNQPAVLKYLITKVHPAIDVNQAADTGNTALHAASNSGNLPLVEMLCACDSINVNCVNPQCENATPLHLSVMHGHNEIVACLLEHGADPSLKMGETSVTA-LATDFDHNEILKML 533          
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A2C9JMD3 (ANK_REP_REGION domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106060032 PE=4 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 1.872e-54
Identity = 123/388 (31.70%), Postives = 202/388 (52.06%), Query Frame = 3
Query:  297 ILNTKHVDKSNGKSLYKSPQIKAALPNIKNCSNSENLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            I N K+VD+S          IK    NI+  SN + +  FM      +  +++ WL ++N  + EL ++    + FV F  FWL+E P  Q++++F+MEY+IL+ ++ +       +  ++ +    L+   F EY +  I   G Y +FL+Y D L S   + YK +L++V+ ST N+   + LL  R  ALV++W+SVINFYRNL G      K+ +  L         R+  +I   FI  + Y I    I    + D   ++LL  AV     ++V+YF++  + +  +N  + +GN+ LH A   G++  V+LL      +VN  N  C+  TPLH+A M+G  +I +CL++HGA+P    G  +TA+ +A      +I  LL
Sbjct:  139 ISNVKNVDRSKSSDSTGQQSIKK---NIR--SNFDEILTFM------DATIVASWLKRSNDAIQELTKYCSSGDNFVYFAQFWLLEFPDAQKKDIFSMEYDILLNEVALAFSVGRESKQVSRRDIIDLLGAVFKEYPMRLIGRHGPY-IFLDYLDILTSERQDQYKKLLSDVRCSTSNRQYAQWLLATRCFALVNVWSSVINFYRNLTGHNSKSSKNFDTSLKG---TFLQRMTESIQFGFIDVVTYLIESGHIK-STYSDSHGKSLLFTAVMCKQPAIVKYFLSLVNPTLDVNQTAETGNTPLHAAANIGDLQIVELLCRCDRINVNCVNYQCEQATPLHLAVMHGHTEIIECLLKHGADPLFKMG-QTTAVQLAKDLGNSQIISLL 509          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: tnksb (tankyrase-1 [Source:NCBI gene;Acc:103045612])

HSP 1 Score: 67.3958 bits (163), Expect = 2.459e-11
Identity = 50/142 (35.21%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      TA+D+A      +I  LL DA     LPS
Sbjct:  740 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---FNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTALDLAT---ADDIRALLMDAMPPDALPS 872          

HSP 2 Score: 57.3806 bits (137), Expect = 3.630e-8
Identity = 45/150 (30.00%), Postives = 75/150 (50.00%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R   A     + T++   + + +N ++     S  L   A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+PS      + A+DM
Sbjct:  557 SDVDY-RFLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPSKKNRDGNMALDM 698          

HSP 3 Score: 49.6766 bits (117), Expect = 7.065e-6
Identity = 42/158 (26.58%), Postives = 73/158 (46.20%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANL----------YEQHEIAKLLHDAN--HVQQLPSESISSLH 1514
            D +    L LA  YN + +VQ  +        ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P+++   + +AID+A            ++ H + +   + +   V++ P E IS  H
Sbjct:  264 DGRKSTPLHLAAGYNRVRIVQLLLQ---YGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLLNCHSKSAIDLAPTPELRDKLTYEFKGHSLLQAAREGDLAKVKKTPQEIISFKH 415          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: tnksb (tankyrase-1 [Source:NCBI gene;Acc:103045612])

HSP 1 Score: 67.3958 bits (163), Expect = 2.463e-11
Identity = 50/142 (35.21%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      TA+D+A      +I  LL DA     LPS
Sbjct:  747 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---FNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTALDLAT---ADDIRALLMDAMPPDALPS 879          

HSP 2 Score: 57.3806 bits (137), Expect = 3.634e-8
Identity = 45/150 (30.00%), Postives = 75/150 (50.00%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R   A     + T++   + + +N ++     S  L   A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+PS      + A+DM
Sbjct:  564 SDVDY-RFLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLH-FAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPSKKNRDGNMALDM 705          

HSP 3 Score: 49.6766 bits (117), Expect = 8.837e-6
Identity = 41/151 (27.15%), Postives = 71/151 (47.02%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANL----------YEQHEIAKLLHDAN--HVQQLPSESISSLH 1514
            L LA  YN + +VQ  +        ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P+++   + +AID+A            ++ H + +   + +   V++ P E IS  H
Sbjct:  278 LHLAAGYNRVRIVQLLLQ---YGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLLNCHSKSAIDLAPTPELRDKLTYEFKGHSLLQAAREGDLAKVKKTPQEIISFKH 422          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: CASKIN2 (CASK interacting protein 2 [Source:NCBI gene;Acc:103032093])

HSP 1 Score: 62.7734 bits (151), Expect = 7.408e-10
Identity = 34/110 (30.91%), Postives = 60/110 (54.55%), Query Frame = 3
Query: 1158 DVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQL 1487
            +    ++    +G   LH A  QG  ++V LL+  G A VN  + D     PLH+AA YG  ++++ L++H +NP MV  +  T +D+A  + + ++ +LL  +N +  L
Sbjct:   70 EAQATVDIKDTNGMRPLHYAAWQGKAESVLLLLRAG-ASVNGASQDGQ--IPLHLAAQYGHYEVSEMLLQHQSNPCMVNKAKKTPLDLACEFGRLKVTQLLLSSNMINTL 176          

HSP 2 Score: 60.077 bits (144), Expect = 5.052e-9
Identity = 54/196 (27.55%), Postives = 93/196 (47.45%), Query Frame = 3
Query:  927 GDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIIN-----CVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLY----EQHEIAKLLHDANHVQQL 1487
            G  Q   I +HL  Q    Y    M + HQ  P +   +NK K           +  L LA  +  L V Q  +++  ++T++       + ++ N+ LHLA   G+ D ++LL++ G  DVN         T LH A++YG+ ++ + L++ G + ++    N TA+D+ N +       +I +LL DA  V Q+
Sbjct:  110 GASQDGQIPLHLAAQYG-HYEVSEMLLQHQSNPCM---VNKAK-----------KTPLDLACEFGRLKVTQLLLSSNMINTLLEGDRKEAIDSAFNTPLHLAARNGHKDIIRLLLKAG-IDVN---RSTKAGTALHEASLYGKTEVVRLLLDAGIDVNIRNTYNQTALDIVNQFTTSHASKDIKQLLRDATGVLQV 286          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: CASKIN2 (CASK interacting protein 2 [Source:NCBI gene;Acc:103032093])

HSP 1 Score: 62.7734 bits (151), Expect = 7.442e-10
Identity = 34/110 (30.91%), Postives = 60/110 (54.55%), Query Frame = 3
Query: 1158 DVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQL 1487
            +    ++    +G   LH A  QG  ++V LL+  G A VN  + D     PLH+AA YG  ++++ L++H +NP MV  +  T +D+A  + + ++ +LL  +N +  L
Sbjct:   70 EAQATVDIKDTNGMRPLHYAAWQGKAESVLLLLRAG-ASVNGASQDGQ--IPLHLAAQYGHYEVSEMLLQHQSNPCMVNKAKKTPLDLACEFGRLKVTQLLLSSNMINTL 176          

HSP 2 Score: 60.077 bits (144), Expect = 5.074e-9
Identity = 54/196 (27.55%), Postives = 93/196 (47.45%), Query Frame = 3
Query:  927 GDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIIN-----CVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLY----EQHEIAKLLHDANHVQQL 1487
            G  Q   I +HL  Q    Y    M + HQ  P +   +NK K           +  L LA  +  L V Q  +++  ++T++       + ++ N+ LHLA   G+ D ++LL++ G  DVN         T LH A++YG+ ++ + L++ G + ++    N TA+D+ N +       +I +LL DA  V Q+
Sbjct:  110 GASQDGQIPLHLAAQYG-HYEVSEMLLQHQSNPCM---VNKAK-----------KTPLDLACEFGRLKVTQLLLSSNMINTLLEGDRKEAIDSAFNTPLHLAARNGHKDIIRLLLKAG-IDVN---RSTKAGTALHEASLYGKTEVVRLLLDAGIDVNIRNTYNQTALDIVNQFTTSHASKDIKQLLRDATGVLQV 286          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000057124.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:21991974:22007825:-1 gene:ENSAMXG00000042087.1 transcript:ENSAMXT00000057124.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 1.941e-9
Identity = 45/145 (31.03%), Postives = 74/145 (51.03%), Query Frame = 3
Query: 1071 FRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGN--SALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLY----EQHEIAKLLHDANHVQQL 1487
             RD   +  L LA  +  +SVVQ  +++   + ++    +  N  S LHLA   G+ID +KLLI+ G   ++I N      T LH AA+ G+ D  + L++ G + S+      TA+D+ N +       EI ++L DA+   Q+
Sbjct:  125 IRDHAGKTPLDLACEFGRVSVVQLLLSSNMCAAMLEPKPSDPNGISPLHLAAKNGHIDIIKLLIQAG---IDI-NRQTKSGTALHEAALCGKTDAVRLLLDSGISASVRNTYCQTALDIVNQFTTTQASREIKQMLRDASAAMQV 265          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009608.1 (pep scaffold:Pmarinus_7.0:GL477242:23155:61557:-1 gene:ENSPMAG00000008655.1 transcript:ENSPMAT00000009608.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.855 bits (159), Expect = 1.474e-11
Identity = 52/154 (33.77%), Postives = 73/154 (47.40%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSESISSLHRSDQV 1529
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+   A VN   TD    TPLH AA  G+  +   L+ HGA+PSM      T +D+A      ++  LL DA     +P E++   H+   +
Sbjct:  797 RDSQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIKYS-ACVNA--TDKWAFTPLHEAAQKGRTQLCALLLAHGADPSMKNQEGQTPLDLAT---ADDVRALLIDA-----MPPEALPVTHKPPNI 936          

HSP 2 Score: 54.6842 bits (130), Expect = 4.968e-8
Identity = 38/118 (32.20%), Postives = 62/118 (52.54%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            RD + R+   L  A  YN +SVV+Y + +      ++     G   LH A   G+ +  +LL++ G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  644 RDMEGRHSTPLHFAAGYNRVSVVEYLLQH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVKRG-AVVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 755          

HSP 3 Score: 50.447 bits (119), Expect = 9.421e-7
Identity = 36/123 (29.27%), Postives = 61/123 (49.59%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ +GA+P+++   + +AID+A   E  E
Sbjct:  331 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLVKHG-ASVNA--MDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHSKSAIDLAPTSELKE 447          

HSP 4 Score: 50.447 bits (119), Expect = 1.000e-6
Identity = 39/120 (32.50%), Postives = 59/120 (49.17%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNT-DCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            RD   R    L  A  +    VV++ + N      ++   + G   LH A   G+ + V LL+  G AD   PN  D  + TPLH AA+ G+ D+   L++HGA+P +      TA+D+A
Sbjct:  175 RDTTGRKSTPLHFAAGFGRKDVVEHLLQN---GANVHARDDGGLIPLHNACSFGHAEVVNLLLRQG-AD---PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPGIRNTDGKTALDLA 287          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008129.1 (pep scaffold:Pmarinus_7.0:GL476358:593185:649018:1 gene:ENSPMAG00000007339.1 transcript:ENSPMAT00000008129.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 4.900e-10
Identity = 37/116 (31.90%), Postives = 56/116 (48.28%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            D Q R  L+++ S   L    +    +     +  V   G SAL  A  +G +  V+ L+ENG A   I + D    TPL +AA YG +++  CL+EHGA+      S  + +D A
Sbjct:  985 DRQGRTPLMVSSSEGHLQTAAFL---HSQGASVAAVDREGLSALSWACLKGRLPVVRFLLENGAA---IEHADKSGRTPLDLAAFYGDENVIDCLIEHGASIDHTDNSGMSPLDRA 1094          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 1.072e-9
Identity = 38/112 (33.93%), Postives = 62/112 (55.36%), Query Frame = 3
Query: 1125 LSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L+VVQ  + N   S   N     G + LH+A   G ++ VK L+++G A V +   +  D TPLH+A+  G+ +I Q L++ G++P+  T S ST +  A+     ++A LL
Sbjct:  423 LNVVQLLLQNGASSNATNV---RGETPLHMASRAGQLEVVKTLLQSG-ARVGVKARE--DQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLL 528          

HSP 2 Score: 51.9878 bits (123), Expect = 3.113e-7
Identity = 37/121 (30.58%), Postives = 61/121 (50.41%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L +A     L VV+  + +      +   +    + LH+A   G  + V+LL++ G +D N P       TPL+ A+  G  D+A  L+E+GA+ S VT    T + +A+ Y + E+A LL
Sbjct:  447 LHMASRAGQLEVVKTLLQS---GARVGVKAREDQTPLHIASRLGKAEIVQLLLQRG-SDPNAPT--ASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLL 561          

HSP 3 Score: 51.9878 bits (123), Expect = 3.278e-7
Identity = 38/137 (27.74%), Postives = 71/137 (51.82%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSESISS 1508
            L +A   N + V++  + +      I+  + SG + +H+A   G+++ V+LL++NG A  N  N   +  TPLHMA+  GQ ++ + L++ GA   +    + T + +A+   + EI +LL         P+ S S+
Sbjct:  381 LHIACKKNRIKVMELLLKH---GASIHTTTESGLTPIHVASFMGHLNVVQLLLQNG-ASSNATNVRGE--TPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGST 511          

HSP 4 Score: 50.8322 bits (120), Expect = 6.870e-7
Identity = 33/91 (36.26%), Postives = 51/91 (56.04%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            I+  +  GN+ALH+A   G  D V++L+E G    NI     +  TPL+MAA     +I + L+++GAN S+ T    T + +A L + HE
Sbjct:   69 IDTATKVGNTALHIAALAGQTDIVRVLVEFG---ANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVA-LQQGHE 155          

HSP 5 Score: 49.2914 bits (116), Expect = 1.831e-6
Identity = 38/108 (35.19%), Postives = 56/108 (51.85%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSE 1496
            IN  + +G +ALHLA  +G++D V  L++    +  I        T LH+AA+ GQ DI + LVE GAN +  + +  T + MA      EI K L D    Q + +E
Sbjct:   36 INTCNQNGLNALHLASKEGHVDVVTELLKR---EAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATE 140          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 1.234e-9
Identity = 38/112 (33.93%), Postives = 62/112 (55.36%), Query Frame = 3
Query: 1125 LSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            L+VVQ  + N   S   N     G + LH+A   G ++ VK L+++G A V +   +  D TPLH+A+  G+ +I Q L++ G++P+  T S ST +  A+     ++A LL
Sbjct:  416 LNVVQLLLQNGASSNATNV---RGETPLHMASRAGQLEVVKTLLQSG-ARVGVKARE--DQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLL 521          

HSP 2 Score: 51.6026 bits (122), Expect = 3.387e-7
Identity = 38/137 (27.74%), Postives = 71/137 (51.82%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSESISS 1508
            L +A   N + V++  + +      I+  + SG + +H+A   G+++ V+LL++NG A  N  N   +  TPLHMA+  GQ ++ + L++ GA   +    + T + +A+   + EI +LL         P+ S S+
Sbjct:  374 LHIACKKNRIKVMELLLKH---GASIHTTTESGLTPIHVASFMGHLNVVQLLLQNG-ASSNATNVRGE--TPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGST 504          

HSP 3 Score: 51.6026 bits (122), Expect = 3.691e-7
Identity = 41/139 (29.50%), Postives = 65/139 (46.76%), Query Frame = 3
Query: 1044 NKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            N    N    R E     L +A     L VV+  + +      +   +    + LH+A   G  + V+LL++ G +D N P       TPL+ A+  G  D+A  L+E+GA+ S VT    T + +A+ Y + E+A LL
Sbjct:  425 NGASSNATNVRGETP---LHMASRAGQLEVVKTLLQS---GARVGVKAREDQTPLHIASRLGKAEIVQLLLQRG-SDPNAPT--ASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLL 554          

HSP 4 Score: 50.8322 bits (120), Expect = 7.102e-7
Identity = 33/91 (36.26%), Postives = 51/91 (56.04%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            I+  +  GN+ALH+A   G  D V++L+E G    NI     +  TPL+MAA     +I + L+++GAN S+ T    T + +A L + HE
Sbjct:   70 IDTATKVGNTALHIAALAGQTDIVRVLVEFG---ANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVA-LQQGHE 156          

HSP 5 Score: 50.0618 bits (118), Expect = 1.064e-6
Identity = 43/142 (30.28%), Postives = 69/142 (48.59%), Query Frame = 3
Query: 1071 FRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSE 1496
            F+ + + + L  A + N   ++ +     D    IN  + +G +ALHLA  +G++D V  L++    +  I        T LH+AA+ GQ DI + LVE GAN +  + +  T + MA      EI K L D    Q + +E
Sbjct:    7 FQSDAATSFLRAARNGNLERLMDHLKGGMD----INTCNQNGLNALHLASKEGHVDVVTELLKR---EAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATE 141          

HSP 6 Score: 47.3654 bits (111), Expect = 6.767e-6
Identity = 34/119 (28.57%), Postives = 57/119 (47.90%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAK-LLHDANHVQQLPSESISSLHRSDQ 1526
            I+ V+  G + LH+A   G ++   LL+E  +A  +      +  TPLH+A  Y  Q +A  L++ GA+P     +  T + +A    Q E+ K LL        L  + ++ LH + Q
Sbjct:  528 ISPVTKKGFTPLHIASKYGRLEVATLLLEK-YASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQ 645          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010339.1 (pep scaffold:Pmarinus_7.0:GL476759:135524:215537:1 gene:ENSPMAG00000009360.1 transcript:ENSPMAT00000010339.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.3066 bits (142), Expect = 1.907e-9
Identity = 41/116 (35.34%), Postives = 56/116 (48.28%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            D Q R  L++A     +  V+Y ++       I CV   G SAL  A  +G+   V+ L+  G A   I +TD +  TPL +AA YG   + Q LVEHGA    V  S    +D A
Sbjct: 1041 DRQGRTALMVASCEGHIGTVEYLLSK---GASIGCVDKEGLSALSWACLKGHQPVVQSLVGRGAA---IDHTDKNGRTPLDLAAFYGDAGVVQYLVEHGAMIEHVDYSGMRPLDRA 1150          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Yeast
Match: HOS4 (Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374])

HSP 1 Score: 70.0922 bits (170), Expect = 4.007e-13
Identity = 45/118 (38.14%), Postives = 66/118 (55.93%), Query Frame = 3
Query: 1071 FRDEQSRNLLILAVSYNSLSVVQYFV--NNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAID 1418
            +RD   R  L +A       VV+  +    YD    IN   N+GN+ALH A  QG+I+ V+LLIENG ADVNI + +    TPL  A+  G  D+ + L+++GA+P++      TA +
Sbjct:  325 YRDSGGRTRLQIACDKGKYDVVKKMIEEGGYD----INDQDNAGNTALHEAALQGHIEIVELLIENG-ADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFE 437          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Yeast
Match: YGL242C_mRNA (Protein of unknown function; N-terminally propionylated in vivo; deletion mutant is viable [Source:SGD;Acc:S000003211])

HSP 1 Score: 51.6026 bits (122), Expect = 3.538e-8
Identity = 40/137 (29.20%), Postives = 72/137 (52.55%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYD-----VSTIINCVSNS-GNSALHLAVCQGNIDAV-KLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQD------IAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDA 1469
            L+ A   N+L +++   ++ D     ++ +IN      GN+ALHL    G+ + + K+L ++G  +++ P  D D  TPLH+   Y Q++      IA+ L+E GA+P +   +N   +D+ +  E  E+  LL  A
Sbjct:   12 LLDAARRNNLDLLETVFDSLDNDPEKIAKLINESKEPLGNTALHLCCKYGSWEVLDKILDQDGEIEID-PQNDVDGDTPLHVTVRYSQEEPEHGTFIARNLIEVGADPRVRNYNNQKPVDLVHGDELDELIDLLQGA 147          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO37759 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SET1])

HSP 1 Score: 159.073 bits (401), Expect = 5.752e-43
Identity = 131/501 (26.15%), Postives = 224/501 (44.71%), Query Frame = 3
Query:  147 MSRGIRDLREIICVSRLCNVYQNEDILNISDQYLGECVN--NNHQFPKPVDKILNTKHVDKS----NGKSLYKSPQIKAA-------LPNI------------------KNCSNSE-------------------NLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEI----HLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNS-TAIDMANLYEQHEIAKLLHDANHVQQ 1484
            MSR +RDLRE+IC+SRL   Y  E+  +   + L       N ++ PK       +          +G   +KSP++          LP I                   + +N E                   N  + + Y   ++  +++EWL +ANK +  L  W      FV+F +FWL +L  ++RR+   ME+ I++++++      +    ++ +    L    FWEY      +   +Y FL     L S   ++YKS+L+NV+ ST NK   +++L  R+  +VSI + VI F++ +     V L   +I    H  D   V       A+   F+   ++ + + +++     D   +  L  +V      V+ Y ++      +   VS SGN+ LH AV  GN   VKLL  N  AD+N  N DC+  TPL +A M G   +   L+  G   ++  G+ + + +D+A   E H+IA++L D++H+ +
Sbjct:    1 MSRSVRDLRELICISRLS--YHGEEEQDPEPENLNAASEDFNGNRVPKDTKTKRKSPKKKVKDKAISGLESHKSPRLSPGGSSKAVILPPIRNSSAGSSGSSSGRNSPASSLTNEELQPCRPFSSIAKKYQPRKTNFDDVLVY---MDATVIAEWLSRANKSVQSLTSWLHSGCNFVHFAHFWLSDLVDSKRRDAIDMEFSIVMDEVQFAFGVGLQGKEISMEDIRSLTTAIFWEYPGKLSDTENQHY-FLTMLICLCSGRQDNYKSLLSNVRCSTNNKQFAQLVLATRSFTIVSICSGVIEFFKQV---SPVNLTHCDITSAPHAQDLISVAKLFAFQAVEKGFLDVFKFLVEEYQLDPVLTIDSSDKTFLFTSVISGQEQVLNYLLSLEPRPNVNKVVSASGNTPLHAAVNCGNQSMVKLL-ANAGADLNAANEDCNGATPLFLAIMSGNLAMVSLLLSLGCRTNVYMGALAVSPLDLAKELELHDIAEML-DSSHITE 490          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO30889 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZG9])

HSP 1 Score: 56.9954 bits (136), Expect = 4.864e-10
Identity = 30/84 (35.71%), Postives = 48/84 (57.14%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMA 1424
            +  V + GN+ LH A   G  D  KLLI+   +DVN  N +  D +PLH++A  G  ++ Q L++ GA+P ++     T ++MA
Sbjct:   21 VKAVDHHGNTPLHCAAAAGRDDIAKLLIDK-WSDVNALNKE--DQSPLHLSARVGSSEVTQLLLDKGADPRLLDAQARTPMEMA 101          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO34688 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNN7])

HSP 1 Score: 52.373 bits (124), Expect = 1.005e-8
Identity = 28/91 (30.77%), Postives = 56/91 (61.54%), Query Frame = 3
Query: 1188 NSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            ++G+S +H A   G+++A+KLL+E+G  D+N    D    +PLH+++  G     + L+E+GA+  + +   +TA+++A    Q ++A+ L
Sbjct:    4 DTGSSPVHKAAANGHLEALKLLLEHG-GDIN--QCDITGSSPLHVSSRNGHLTCVKYLIENGADHKLKSKKGNTALNVAKSSAQQKVAEYL 91          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO48893 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHQ3])

HSP 1 Score: 52.7582 bits (125), Expect = 2.663e-8
Identity = 31/87 (35.63%), Postives = 48/87 (55.17%), Query Frame = 3
Query: 1158 DVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAID 1418
            D  +IIN    +   ALH  V +GN+  V++L+  G ADVN+ N +    TPLH  A+    D+A+ L++  ANP +   +  T +D
Sbjct:   35 DPKSIINGTQGNQGPALHQLVFEGNLKCVRMLVNLG-ADVNMQNEEG--FTPLHYCALSNNFDMAKFLMKKSANPDIADYNGKTPVD 118          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO39113 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB41])

HSP 1 Score: 52.373 bits (124), Expect = 5.835e-8
Identity = 38/121 (31.40%), Postives = 60/121 (49.59%), Query Frame = 3
Query: 1098 LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLL 1460
            +I A  +N++   +  +       I NC    G +ALH A  +G+   V+LL+ +G  DVN+   D D+ T LH+AAM G   I + L+  GAN +       TA  +A    + E+ + L
Sbjct:   69 IICAAKFNAIESCRVLLRAGADVNITNCY---GQTALHHATRRGHSKMVELLLRDGQMDVNV--VDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTL 184          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000040446.1 (caskin-2 [Source:NCBI gene;Acc:101167247])

HSP 1 Score: 66.6254 bits (161), Expect = 4.995e-11
Identity = 35/99 (35.35%), Postives = 59/99 (59.60%), Query Frame = 3
Query: 1191 SGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQL 1487
            +G   LH A  QG  D+V LL+  G A VN  +  CD   PLH++A YG  ++++ L++H +NP ++  +  T +D+A  + + ++A+LL  +N V  L
Sbjct:   81 NGMRPLHYAAWQGKSDSVLLLLRAG-ASVN--SLSCDGQIPLHLSAQYGHYEVSEMLLQHQSNPCLMNKAKKTPLDLACEFGRLKVAQLLLSSNMVTTL 176          

HSP 2 Score: 55.4546 bits (132), Expect = 1.235e-7
Identity = 56/191 (29.32%), Postives = 90/191 (47.12%), Query Frame = 3
Query:  948 IEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSA-------LHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLY----EQHEIAKLLHDANHVQQL 1487
            I +HL  Q    Y    M + HQ  P L   +NK K           +  L LA  +  L V Q  +++  V+T++      G+S+       LHLA   G+ D +KLL++ G  D+N         T LH AA+YG+ ++ + L++ G N ++    N TA+D+ N +       EI +LL +A+   Q+
Sbjct:  117 IPLHLSAQYG-HYEVSEMLLQHQSNPCL---MNKAK-----------KTPLDLACEFGRLKVAQLLLSSNMVTTLLEG-DGGGDSSDWPSTTPLHLAARNGHKDIIKLLLKAG-IDMN---RATKAGTSLHEAALYGKTEVVRLLLDAGINVNVRNTYNQTALDIVNQFTTSTASREIKQLLREASSSLQV 287          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000040936.1 (caskin-2 [Source:NCBI gene;Acc:101167247])

HSP 1 Score: 66.6254 bits (161), Expect = 5.016e-11
Identity = 35/99 (35.35%), Postives = 59/99 (59.60%), Query Frame = 3
Query: 1191 SGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQL 1487
            +G   LH A  QG  D+V LL+  G A VN  +  CD   PLH++A YG  ++++ L++H +NP ++  +  T +D+A  + + ++A+LL  +N V  L
Sbjct:   81 NGMRPLHYAAWQGKSDSVLLLLRAG-ASVN--SLSCDGQIPLHLSAQYGHYEVSEMLLQHQSNPCLMNKAKKTPLDLACEFGRLKVAQLLLSSNMVTTL 176          

HSP 2 Score: 55.4546 bits (132), Expect = 1.239e-7
Identity = 56/191 (29.32%), Postives = 90/191 (47.12%), Query Frame = 3
Query:  948 IEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSA-------LHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLY----EQHEIAKLLHDANHVQQL 1487
            I +HL  Q    Y    M + HQ  P L   +NK K           +  L LA  +  L V Q  +++  V+T++      G+S+       LHLA   G+ D +KLL++ G  D+N         T LH AA+YG+ ++ + L++ G N ++    N TA+D+ N +       EI +LL +A+   Q+
Sbjct:  117 IPLHLSAQYG-HYEVSEMLLQHQSNPCL---MNKAK-----------KTPLDLACEFGRLKVAQLLLSSNMVTTLLEG-DGGGDSSDWPSTTPLHLAARNGHKDIIKLLLKAG-IDMN---RATKAGTSLHEAALYGKTEVVRLLLDAGINVNVRNTYNQTALDIVNQFTTSTASREIKQLLREASSSLQV 287          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000047046.1 (caskin-2 [Source:NCBI gene;Acc:101167247])

HSP 1 Score: 66.6254 bits (161), Expect = 5.047e-11
Identity = 35/99 (35.35%), Postives = 59/99 (59.60%), Query Frame = 3
Query: 1191 SGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQL 1487
            +G   LH A  QG  D+V LL+  G A VN  +  CD   PLH++A YG  ++++ L++H +NP ++  +  T +D+A  + + ++A+LL  +N V  L
Sbjct:  106 NGMRPLHYAAWQGKSDSVLLLLRAG-ASVN--SLSCDGQIPLHLSAQYGHYEVSEMLLQHQSNPCLMNKAKKTPLDLACEFGRLKVAQLLLSSNMVTTL 201          

HSP 2 Score: 55.4546 bits (132), Expect = 1.245e-7
Identity = 56/191 (29.32%), Postives = 90/191 (47.12%), Query Frame = 3
Query:  948 IEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSA-------LHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLY----EQHEIAKLLHDANHVQQL 1487
            I +HL  Q    Y    M + HQ  P L   +NK K           +  L LA  +  L V Q  +++  V+T++      G+S+       LHLA   G+ D +KLL++ G  D+N         T LH AA+YG+ ++ + L++ G N ++    N TA+D+ N +       EI +LL +A+   Q+
Sbjct:  142 IPLHLSAQYG-HYEVSEMLLQHQSNPCL---MNKAK-----------KTPLDLACEFGRLKVAQLLLSSNMVTTLLEG-DGGGDSSDWPSTTPLHLAARNGHKDIIKLLLKAG-IDMN---RATKAGTSLHEAALYGKTEVVRLLLDAGINVNVRNTYNQTALDIVNQFTTSTASREIKQLLREASSSLQV 312          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000038944.1 (tankyrase-1 [Source:NCBI gene;Acc:101158122])

HSP 1 Score: 65.0846 bits (157), Expect = 1.496e-10
Identity = 49/142 (34.51%), Postives = 67/142 (47.18%), Query Frame = 3
Query: 1074 RDEQSRNL--LILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      T +D+A      +I  LL DA     LPS
Sbjct:  778 RDTQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT---ADDIRALLIDAMPPDALPS 910          

HSP 2 Score: 56.6102 bits (135), Expect = 5.123e-8
Identity = 44/150 (29.33%), Postives = 75/150 (50.00%), Query Frame = 3
Query:  972 SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            SDV Y R+  A     + T++     + +N ++     S  L   A  YN +SVV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +T +D+
Sbjct:  595 SDVDY-RLLEAAKAGDLDTIKSLCTPQNVNCRDLEGRHSTPLH-FAAGYNRVSVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 736          

HSP 3 Score: 50.0618 bits (118), Expect = 5.414e-6
Identity = 36/123 (29.27%), Postives = 61/123 (49.59%), Query Frame = 3
Query: 1077 DEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE 1445
            D +    L LA  YN + +VQ  + +      ++     G   LH A   G+ +  +LL+++G A VN    D    TPLH AA   + ++   L+ HGA+P+++   + +++DMA   E  E
Sbjct:  313 DGRKSTPLHLAAGYNRVRIVQLLLQH---GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG-ACVNA--MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLLNCHSKSSVDMAPTPELKE 429          
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: tnksb (tankyrase-1-like [Source:NCBI gene;Acc:105353570])

HSP 1 Score: 64.6994 bits (156), Expect = 1.736e-10
Identity = 50/142 (35.21%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1074 RDEQSRN--LLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPS 1493
            RD Q RN   L LA  YN+L V +Y + +      +N     G   LH A   G++D   LLI+    +  +  TD    TPLH AA  G+  +   L+ HGA+P+M      TA+D+A      +I  LL DA     LPS
Sbjct:  751 RDAQGRNSTPLHLAAGYNNLEVAEYLLEH---GADVNAQDKGGLIPLHNAASYGHVDIAALLIKY---NTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTALDLAT---ADDIRALLMDAMPPDALPS 883          

HSP 2 Score: 56.6102 bits (135), Expect = 6.262e-8
Identity = 55/194 (28.35%), Postives = 94/194 (48.45%), Query Frame = 3
Query:  843 KILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQ-SDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDM 1421
            K+LL+  A A +    S+  F    +G   VQ + +  ++P + SDV Y R   A     + T+Q     + +N ++     S   L  A  YN ++VV+Y +++      ++     G   LH A   G+ +  +LL+ +G A VN+   D    TPLH AA  G+ +I + L++HGA+P+      +  +DM
Sbjct:  528 KLLLSFGADAAI---VSLQGFTAAQMGNEAVQ-QILNENVPTRNSDVDY-RFLEAAKAGDLDTVQQLCTPQNVNCRDLEGRHS-TPLHFAAGYNRVAVVEYLLHH---GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG-ASVNV--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNIPLDM 709          
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000017292.1 (SMESG000017292.1)

HSP 1 Score: 949.118 bits (2452), Expect = 0.000e+0
Identity = 462/465 (99.35%), Postives = 462/465 (99.35%), Query Frame = 3
Query:  147 MSRGIRDLREIICVSRLCNVYQNEDILNISDQYLGECVNNNHQFPKPVDKILNTKHVDKSNGKSLYKSPQIKAALPNIKNCSNSENLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSESISSLHRSDQVIVDK 1541
            MSRGIRDLREIICVSRLCNVYQNEDILNISDQYLGECVNNN QFPKPVDKILN KHVDKSNGKSLYKSP IKAALPNIKNCSNSENLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSESISSLHRSDQVIVDK
Sbjct:    1 MSRGIRDLREIICVSRLCNVYQNEDILNISDQYLGECVNNNPQFPKPVDKILNKKHVDKSNGKSLYKSPPIKAALPNIKNCSNSENLHEFMKYFEMINEKLLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEYEILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLFLEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSVINFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWINKKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSESISSLHRSDQVIVDK 465          
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1)

HSP 1 Score: 58.9214 bits (141), Expect = 8.104e-9
Identity = 41/110 (37.27%), Postives = 66/110 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLLHDANHVQQ-LPS 1493
            I+  +  GNSALH+A   G  + VK+L+ENG A+VN+ +T+    TPL+MAA     ++   L+ +GA+ ++ T    T + +A L + HE  +A LL + N  +Q LP+
Sbjct:   70 IDATTKKGNSALHIASLAGKFEVVKILVENG-ANVNLQSTNG--FTPLYMAAQENHLEVVTFLINNGADQTITTEDGFTPLAVA-LQQGHERIVALLLENDNRSKQRLPA 175          

HSP 2 Score: 54.6842 bits (130), Expect = 2.013e-7
Identity = 37/101 (36.63%), Postives = 58/101 (57.43%), Query Frame = 3
Query: 1074 RDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGA 1376
            R +Q    L +AV  N ++ V   +N+ +V   +N  S+SG + LH+A   GN  + +LLIE   ADVN    +  + TPLH+AA +G+  + Q L++ GA
Sbjct:  168 RSKQRLPALHIAVKKNDVNAVNLLLNSSEVD--VNHQSSSGFTPLHIAAHYGNEKSAQLLIEQ-KADVNFQAKN--NITPLHVAAKWGRSGMVQLLIDSGA 263          

HSP 3 Score: 51.2174 bits (121), Expect = 2.406e-6
Identity = 34/135 (25.19%), Postives = 68/135 (50.37%), Query Frame = 3
Query: 1062 LQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHD 1466
            + + +  +++  L +A    +L ++  F+ +    +  N  +    +ALH+A  +G  +A+ LL+++G     I        TPLH+AA Y +  +A  L++  ANP+    +  T + +A  Y   ++A+LL D
Sbjct:  462 IPDAKARENQTPLHVATKIGNLELITLFLQS---GSDPNVATRDNYTALHVAAKEGRSEAISLLLDSG---AKIEAETKRGFTPLHIAAKYDKVGVASILLQKKANPNATGKNGLTPLHVATHYNHEKVAQLLLD 590          

HSP 4 Score: 50.447 bits (119), Expect = 3.534e-6
Identity = 31/89 (34.83%), Postives = 52/89 (58.43%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDA 1469
            ALH+AV + +++AV LL+ +   DVN  +      TPLH+AA YG +  AQ L+E  A+ +    +N T + +A  + +  + +LL D+
Sbjct:  175 ALHIAVKKNDVNAVNLLLNSSEVDVN--HQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDS 261          
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1)

HSP 1 Score: 58.9214 bits (141), Expect = 8.104e-9
Identity = 41/110 (37.27%), Postives = 66/110 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLLHDANHVQQ-LPS 1493
            I+  +  GNSALH+A   G  + VK+L+ENG A+VN+ +T+    TPL+MAA     ++   L+ +GA+ ++ T    T + +A L + HE  +A LL + N  +Q LP+
Sbjct:   70 IDATTKKGNSALHIASLAGKFEVVKILVENG-ANVNLQSTNG--FTPLYMAAQENHLEVVTFLINNGADQTITTEDGFTPLAVA-LQQGHERIVALLLENDNRSKQRLPA 175          

HSP 2 Score: 54.6842 bits (130), Expect = 2.013e-7
Identity = 37/101 (36.63%), Postives = 58/101 (57.43%), Query Frame = 3
Query: 1074 RDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGA 1376
            R +Q    L +AV  N ++ V   +N+ +V   +N  S+SG + LH+A   GN  + +LLIE   ADVN    +  + TPLH+AA +G+  + Q L++ GA
Sbjct:  168 RSKQRLPALHIAVKKNDVNAVNLLLNSSEVD--VNHQSSSGFTPLHIAAHYGNEKSAQLLIEQ-KADVNFQAKN--NITPLHVAAKWGRSGMVQLLIDSGA 263          

HSP 3 Score: 51.2174 bits (121), Expect = 2.385e-6
Identity = 34/135 (25.19%), Postives = 68/135 (50.37%), Query Frame = 3
Query: 1062 LQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHD 1466
            + + +  +++  L +A    +L ++  F+ +    +  N  +    +ALH+A  +G  +A+ LL+++G     I        TPLH+AA Y +  +A  L++  ANP+    +  T + +A  Y   ++A+LL D
Sbjct:  462 IPDAKARENQTPLHVATKIGNLELITLFLQS---GSDPNVATRDNYTALHVAAKEGRSEAISLLLDSG---AKIEAETKRGFTPLHIAAKYDKVGVASILLQKKANPNATGKNGLTPLHVATHYNHEKVAQLLLD 590          

HSP 4 Score: 50.447 bits (119), Expect = 3.534e-6
Identity = 31/89 (34.83%), Postives = 52/89 (58.43%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDA 1469
            ALH+AV + +++AV LL+ +   DVN  +      TPLH+AA YG +  AQ L+E  A+ +    +N T + +A  + +  + +LL D+
Sbjct:  175 ALHIAVKKNDVNAVNLLLNSSEVDVN--HQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDS 261          
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1)

HSP 1 Score: 58.9214 bits (141), Expect = 8.248e-9
Identity = 41/110 (37.27%), Postives = 66/110 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLLHDANHVQQ-LPS 1493
            I+  +  GNSALH+A   G  + VK+L+ENG A+VN+ +T+    TPL+MAA     ++   L+ +GA+ ++ T    T + +A L + HE  +A LL + N  +Q LP+
Sbjct:   70 IDATTKKGNSALHIASLAGKFEVVKILVENG-ANVNLQSTNG--FTPLYMAAQENHLEVVTFLINNGADQTITTEDGFTPLAVA-LQQGHERIVALLLENDNRSKQRLPA 175          

HSP 2 Score: 54.6842 bits (130), Expect = 2.049e-7
Identity = 37/101 (36.63%), Postives = 58/101 (57.43%), Query Frame = 3
Query: 1074 RDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGA 1376
            R +Q    L +AV  N ++ V   +N+ +V   +N  S+SG + LH+A   GN  + +LLIE   ADVN    +  + TPLH+AA +G+  + Q L++ GA
Sbjct:  168 RSKQRLPALHIAVKKNDVNAVNLLLNSSEVD--VNHQSSSGFTPLHIAAHYGNEKSAQLLIEQ-KADVNFQAKN--NITPLHVAAKWGRSGMVQLLIDSGA 263          

HSP 3 Score: 50.8322 bits (120), Expect = 2.512e-6
Identity = 37/136 (27.21%), Postives = 70/136 (51.47%), Query Frame = 3
Query: 1062 LQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNS-TAIDMANLYEQHEIAKLLHD 1466
            + + +  +++  L +A    +L ++  F+ +    +  N  +    +ALH+A  +G  +A+ LL+++G     I        TPLH+AA Y +  +A  L++  ANP+  TG N  T + +A  Y   ++A+LL D
Sbjct:  462 IPDAKARENQTPLHVATKIGNLELITLFLQS---GSDPNVATRDNYTALHVAAKEGRSEAISLLLDSG---AKIEAETKRGFTPLHIAAKYDKVGVASILLQKKANPN-ATGKNGLTPLHVATHYNHEKVAQLLLD 590          

HSP 4 Score: 50.447 bits (119), Expect = 3.597e-6
Identity = 31/89 (34.83%), Postives = 52/89 (58.43%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDA 1469
            ALH+AV + +++AV LL+ +   DVN  +      TPLH+AA YG +  AQ L+E  A+ +    +N T + +A  + +  + +LL D+
Sbjct:  175 ALHIAVKKNDVNAVNLLLNSSEVDVN--HQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDS 261          
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1)

HSP 1 Score: 58.9214 bits (141), Expect = 8.298e-9
Identity = 41/110 (37.27%), Postives = 66/110 (60.00%), Query Frame = 3
Query: 1173 INCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHE--IAKLLHDANHVQQ-LPS 1493
            I+  +  GNSALH+A   G  + VK+L+ENG A+VN+ +T+    TPL+MAA     ++   L+ +GA+ ++ T    T + +A L + HE  +A LL + N  +Q LP+
Sbjct:   70 IDATTKKGNSALHIASLAGKFEVVKILVENG-ANVNLQSTNG--FTPLYMAAQENHLEVVTFLINNGADQTITTEDGFTPLAVA-LQQGHERIVALLLENDNRSKQRLPA 175          

HSP 2 Score: 54.299 bits (129), Expect = 2.170e-7
Identity = 37/101 (36.63%), Postives = 58/101 (57.43%), Query Frame = 3
Query: 1074 RDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGA 1376
            R +Q    L +AV  N ++ V   +N+ +V   +N  S+SG + LH+A   GN  + +LLIE   ADVN    +  + TPLH+AA +G+  + Q L++ GA
Sbjct:  168 RSKQRLPALHIAVKKNDVNAVNLLLNSSEVD--VNHQSSSGFTPLHIAAHYGNEKSAQLLIEQ-KADVNFQAKN--NITPLHVAAKWGRSGMVQLLIDSGA 263          

HSP 3 Score: 50.8322 bits (120), Expect = 2.506e-6
Identity = 34/135 (25.19%), Postives = 68/135 (50.37%), Query Frame = 3
Query: 1062 LQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSGNSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHD 1466
            + + +  +++  L +A    +L ++  F+ +    +  N  +    +ALH+A  +G  +A+ LL+++G     I        TPLH+AA Y +  +A  L++  ANP+    +  T + +A  Y   ++A+LL D
Sbjct:  462 IPDAKARENQTPLHVATKIGNLELITLFLQS---GSDPNVATRDNYTALHVAAKEGRSEAISLLLDSG---AKIEAETKRGFTPLHIAAKYDKVGVASILLQKKANPNATGKNGLTPLHVATHYNHEKVAQLLLD 590          

HSP 4 Score: 50.447 bits (119), Expect = 3.810e-6
Identity = 31/89 (34.83%), Postives = 52/89 (58.43%), Query Frame = 3
Query: 1203 ALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQDIAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDA 1469
            ALH+AV + +++AV LL+ +   DVN  +      TPLH+AA YG +  AQ L+E  A+ +    +N T + +A  + +  + +LL D+
Sbjct:  175 ALHIAVKKNDVNAVNLLLNSSEVDVN--HQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDS 261          
The following BLAST results are available for this feature:
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CASKIN19.332e-1130.50CASK interacting protein 1 [Source:HGNC Symbol;Acc... [more]
ANKS1A1.310e-1031.58ankyrin repeat and sterile alpha motif domain cont... [more]
TNKS3.122e-1033.80tankyrase [Source:HGNC Symbol;Acc:HGNC:11941][more]
TNKS3.122e-1033.80tankyrase [Source:HGNC Symbol;Acc:HGNC:11941][more]
TNKS3.122e-1033.80tankyrase [Source:HGNC Symbol;Acc:HGNC:11941][more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-443.254e-931.40AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-443.254e-931.40AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-443.261e-931.40AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-443.261e-931.40AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-443.267e-931.40AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nompC4.140e-1028.99gene:FBgn0016920 transcript:FBtr0347408[more]
nompC4.165e-1028.99gene:FBgn0016920 transcript:FBtr0300012[more]
nompC4.514e-1028.99gene:FBgn0016920 transcript:FBtr0347409[more]
nompC5.036e-1028.99gene:FBgn0016920 transcript:FBtr0343224[more]
nompC5.347e-1028.99gene:FBgn0016920 transcript:FBtr0304843[more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tnksa9.169e-1134.51tankyrase, TRF1-interacting ankyrin-related ADP-ri... [more]
tnksa9.169e-1134.51tankyrase, TRF1-interacting ankyrin-related ADP-ri... [more]
tnksa9.169e-1134.51tankyrase, TRF1-interacting ankyrin-related ADP-ri... [more]
tnksa9.220e-1134.51tankyrase, TRF1-interacting ankyrin-related ADP-ri... [more]
tnksb9.585e-1135.92tankyrase, TRF1-interacting ankyrin-related ADP-ri... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyp1a13.887e-1139.29cytochrome P450 family 1 subfamily A member 1 [Sou... [more]
foxj32.037e-1033.80forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185... [more]
foxj32.040e-1033.80forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185... [more]
foxj32.044e-1033.80forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185... [more]
foxj32.049e-1033.80forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Anks15.490e-1132.46ankyrin repeat and SAM domain containing 1 [Source... [more]
Anks15.543e-1132.46ankyrin repeat and SAM domain containing 1 [Source... [more]
Caskin19.835e-1129.79CASK interacting protein 1 [Source:MGI Symbol;Acc:... [more]
Caskin19.946e-1129.79CASK interacting protein 1 [Source:MGI Symbol;Acc:... [more]
Tnks2.141e-1033.80tankyrase, TRF1-interacting ankyrin-related ADP-ri... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P40480|HOS4_YEAST2.782e-1138.14Protein HOS4 OS=Saccharomyces cerevisiae (strain A... [more]
sp|Q8WXD9|CSKI1_HUMAN4.482e-1030.50Caskin-1 OS=Homo sapiens OX=9606 GN=CASKIN1 PE=1 S... [more]
sp|Q92625|ANS1A_HUMAN6.291e-1031.58Ankyrin repeat and SAM domain-containing protein 1... [more]
sp|Q6P9K8|CSKI1_MOUSE6.957e-1029.79Caskin-1 OS=Mus musculus OX=10090 GN=Caskin1 PE=1 ... [more]
sp|Q6PFX9|TNKS1_MOUSE1.497e-933.80Poly [ADP-ribose] polymerase tankyrase-1 OS=Mus mu... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267ENP05.617e-6328.45ANK_REP_REGION domain-containing protein OS=Macros... [more]
A0A267FXI53.304e-6228.51ANK_REP_REGION domain-containing protein OS=Macros... [more]
K1QYG98.879e-5832.77Caskin-1 OS=Crassostrea gigas OX=29159 GN=CGI_1002... [more]
A0A433SL013.950e-5629.46ANK_REP_REGION domain-containing protein OS=Elysia... [more]
A0A2C9JMD31.872e-5431.70ANK_REP_REGION domain-containing protein OS=Biomph... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tnksb2.459e-1135.21tankyrase-1 [Source:NCBI gene;Acc:103045612][more]
tnksb2.463e-1135.21tankyrase-1 [Source:NCBI gene;Acc:103045612][more]
CASKIN27.408e-1030.91CASK interacting protein 2 [Source:NCBI gene;Acc:1... [more]
CASKIN27.442e-1030.91CASK interacting protein 2 [Source:NCBI gene;Acc:1... [more]
ENSAMXT00000057124.11.941e-931.03pep primary_assembly:Astyanax_mexicanus-2.0:12:219... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009608.11.474e-1133.77pep scaffold:Pmarinus_7.0:GL477242:23155:61557:-1 ... [more]
ENSPMAT00000008129.14.900e-1031.90pep scaffold:Pmarinus_7.0:GL476358:593185:649018:1... [more]
ENSPMAT00000000093.11.072e-933.93pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 g... [more]
ENSPMAT00000000095.11.234e-933.93pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 g... [more]
ENSPMAT00000010339.11.907e-935.34pep scaffold:Pmarinus_7.0:GL476759:135524:215537:1... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
HOS44.007e-1338.14Subunit of the Set3 complex; complex is a meiotic-... [more]
YGL242C_mRNA3.538e-829.20Protein of unknown function; N-terminally propiony... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO377595.752e-4326.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO308894.864e-1035.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO346881.005e-830.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO488932.663e-835.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO391135.835e-831.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000040446.14.995e-1135.35caskin-2 [Source:NCBI gene;Acc:101167247][more]
ENSORLT00000040936.15.016e-1135.35caskin-2 [Source:NCBI gene;Acc:101167247][more]
ENSORLT00000047046.15.047e-1135.35caskin-2 [Source:NCBI gene;Acc:101167247][more]
ENSORLT00000038944.11.496e-1034.51tankyrase-1 [Source:NCBI gene;Acc:101158122][more]
tnksb1.736e-1035.21tankyrase-1-like [Source:NCBI gene;Acc:105353570][more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017292.10.000e+099.35SMESG000017292.1[more]
SMESG000000606.18.104e-937.27SMESG000000606.1[more]
SMESG000000606.18.104e-937.27SMESG000000606.1[more]
SMESG000000606.18.248e-937.27SMESG000000606.1[more]
SMESG000000606.18.298e-937.27SMESG000000606.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029206 ID=SMED30029206|Name=ANK_REP_REGION domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1581bp
GTTATTTTACTACAGCCTGTAATGGCAGGAAAATTAATTTAAATAATTAC
ACTATTTAAGTCAAATTTAAATAATATAAAATAAGTTAATACTGTAAAAT
ATTATCAAATATATTTCGTACTAAATGAATGTAATTTATTTTTGTAATGA
GTAGAGGAATTAGAGACCTGAGAGAAATTATCTGCGTTTCTCGCCTATGC
AATGTTTATCAAAACGAAGATATTCTTAATATTTCTGATCAATATTTAGG
GGAATGTGTGAATAATAATCATCAATTCCCTAAACCTGTTGATAAGATTC
TAAATACGAAGCATGTTGATAAATCAAATGGTAAATCATTATATAAAAGC
CCCCAAATTAAAGCTGCATTGCCAAATATAAAGAATTGTTCAAATAGCGA
AAATTTACATGAATTCATGAAGTATTTCGAAATGATTAATGAAAAATTGC
TCAGTGAATGGCTGTGTAAAGCTAATAAGCAACTCCATGAACTAATTGAA
TGGGCTCAAGATAACAATGCCTTCGTTAATTTCACTAATTTCTGGCTTGT
GGAATTGCCATCAAATCAACGCCGAGAGCTATTTGCCATGGAATATGAAA
TTCTAGTTGAACAAATCAAGATCGGGCTAGTAAAATATATTCACAACAAT
AGCCTTGCTGATAAATTGACAAATCAGTTGATATTGATTTCATTTTGGGA
GTATCAGTTACATTTTATATCTTCGTCCGGTGGATATTATCTATTTCTCG
AATATTTCGATGGCCTTGTGTCTATTGGTTGTGAAAGTTACAAATCAATT
CTCACGAATGTCAAATTTTCCACTCAAAATAAGCATCTCATCAAAATTTT
ACTCACCATACGAGCTCTGGCACTTGTTTCAATCTGGACATCAGTGATTA
ATTTTTATCGCAATCTGATTGGTCGAGGTGACGTCCAGTTGAAATCGATT
GAAATTCATTTGCCCGATCAATCCGATGTCATGTACAGTCGAATATGCAT
GGCGATTTGCCATCAATTCATTCCCACTTTGCAATATTGGATAAATAAAA
AGAAAATCAATTTGCAAGAATTCCGTGATGAGCAAAGCAGAAATTTGCTG
ATTCTCGCTGTCAGTTACAACAGTCTTTCAGTTGTCCAGTATTTTGTCAA
CAACTATGATGTGAGCACAATCATTAATTGTGTGAGCAACTCCGGGAATT
CGGCGCTACATTTAGCAGTTTGTCAGGGCAACATCGACGCAGTGAAATTG
CTGATTGAGAACGGGCATGCCGATGTGAATATTCCCAATACCGATTGTGA
CGATTGCACTCCTCTCCATATGGCAGCCATGTATGGTCAGCAAGATATTG
CACAATGTCTGGTTGAGCATGGAGCTAATCCAAGCATGGTAACCGGTAGC
AATTCTACTGCCATCGATATGGCTAACTTGTATGAACAACATGAGATTGC
CAAGCTACTACATGATGCTAATCACGTTCAACAGCTCCCTTCTGAATCAA
TATCATCCTTACACAGATCTGATCAAGTCATTGTTGATAAATAATAATAA
ATTCGGCTTGTGTTCATTATTGATTATATTT
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protein sequence of SMED30029206-orf-1

>SMED30029206-orf-1 ID=SMED30029206-orf-1|Name=SMED30029206-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=466bp
MSRGIRDLREIICVSRLCNVYQNEDILNISDQYLGECVNNNHQFPKPVDK
ILNTKHVDKSNGKSLYKSPQIKAALPNIKNCSNSENLHEFMKYFEMINEK
LLSEWLCKANKQLHELIEWAQDNNAFVNFTNFWLVELPSNQRRELFAMEY
EILVEQIKIGLVKYIHNNSLADKLTNQLILISFWEYQLHFISSSGGYYLF
LEYFDGLVSIGCESYKSILTNVKFSTQNKHLIKILLTIRALALVSIWTSV
INFYRNLIGRGDVQLKSIEIHLPDQSDVMYSRICMAICHQFIPTLQYWIN
KKKINLQEFRDEQSRNLLILAVSYNSLSVVQYFVNNYDVSTIINCVSNSG
NSALHLAVCQGNIDAVKLLIENGHADVNIPNTDCDDCTPLHMAAMYGQQD
IAQCLVEHGANPSMVTGSNSTAIDMANLYEQHEIAKLLHDANHVQQLPSE
SISSLHRSDQVIVDK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR036770Ankyrin_rpt-contain_sf
IPR002110Ankyrin_rpt
IPR020683Ankyrin_rpt-contain_dom
IPR029155SIPAR
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 313..345
e-value: 160.0
score: 10.9
coord: 418..447
e-value: 2300.0
score: 2.3
coord: 349..379
e-value: 1.0E-5
score: 35.0
coord: 385..414
e-value: 4.2E-6
score: 36.3
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 385..417
score: 11.808
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 349..373
score: 11.327
NoneNo IPR availablePFAMPF13857Ank_5coord: 386..426
e-value: 6.7E-7
score: 29.5
NoneNo IPR availablePANTHERPTHR24134FAMILY NOT NAMEDcoord: 310..442
coord: 308..382
IPR029155SIPAR domainPFAMPF15487FAM220coord: 80..243
e-value: 3.5E-33
score: 115.4
IPR020683Ankyrin repeat-containing domainPFAMPF12796Ank_2coord: 294..379
e-value: 1.3E-11
score: 44.9
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 313..438
score: 22.225
IPR036770Ankyrin repeat-containing domain superfamilyGENE3DG3DSA:1.25.40.20coord: 266..462
e-value: 9.7E-37
score: 128.8
IPR036770Ankyrin repeat-containing domain superfamilySUPERFAMILYSSF48403Ankyrin repeatcoord: 270..438