SCP domain-containing protein

Overview
NameSCP domain-containing protein
Smed IDSMED30029130
Length (bp)719
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SCP domain-containing protein (SMED30029130) t-SNE clustered cells

Violin plots show distribution of expression levels for SCP domain-containing protein (SMED30029130) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SCP domain-containing protein (SMED30029130) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SCP domain-containing protein (SMED30029130) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029130

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30029130h1SMcG0001350 SmedASXL_006724SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30029130h1SMcG0001350 dd_Smed_v4_6756_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30029130h1SMcG0001350 dd_Smed_v4_6756_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30029130h1SMcG0001350 dd_Smed_v4_6756_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Human
Match: PI15 (peptidase inhibitor 15 [Source:HGNC Symbol;Acc:HGNC:8946])

HSP 1 Score: 110.538 bits (275), Expect = 8.552e-29
Identity = 64/189 (33.86%), Postives = 101/189 (53.44%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQ--PPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            +   ++ + +  ++ I I   H  V G+  PPAANM+ M W++  A  A+ WA  C +DH P+   +F     +GQN++    +  ++ + V+ W+DEVK + F Y  +C            C HYT +VWA ++ +GC +  C N  +        +YLVCNYAP GN   + PYKVG+PC+ CP  +
Sbjct:   53 IPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRF-----LGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSY 236
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Human
Match: PI15 (peptidase inhibitor 15 [Source:HGNC Symbol;Acc:HGNC:8946])

HSP 1 Score: 110.538 bits (275), Expect = 8.552e-29
Identity = 64/189 (33.86%), Postives = 101/189 (53.44%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQ--PPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            +   ++ + +  ++ I I   H  V G+  PPAANM+ M W++  A  A+ WA  C +DH P+   +F     +GQN++    +  ++ + V+ W+DEVK + F Y  +C            C HYT +VWA ++ +GC +  C N  +        +YLVCNYAP GN   + PYKVG+PC+ CP  +
Sbjct:   53 IPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRF-----LGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSY 236
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Human
Match: PI15 (peptidase inhibitor 15 [Source:HGNC Symbol;Acc:HGNC:8946])

HSP 1 Score: 110.538 bits (275), Expect = 8.552e-29
Identity = 64/189 (33.86%), Postives = 101/189 (53.44%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQ--PPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            +   ++ + +  ++ I I   H  V G+  PPAANM+ M W++  A  A+ WA  C +DH P+   +F     +GQN++    +  ++ + V+ W+DEVK + F Y  +C            C HYT +VWA ++ +GC +  C N  +        +YLVCNYAP GN   + PYKVG+PC+ CP  +
Sbjct:   53 IPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRF-----LGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSY 236
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Human
Match: CRISP3 (cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904])

HSP 1 Score: 107.842 bits (268), Expect = 1.061e-27
Identity = 65/170 (38.24%), Postives = 93/170 (54.71%), Query Frame = 1 
Query:  106 TEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNI-AYWYSQNVTEGVQFWFDEVKGFDFYTG-NCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQK--PYKVGMPCTECPE 603
            T+ + +++  HN++R  V        PPA NM +M+WN EAA  AQKWA++C + H   K+R   S +  G+N+     S + ++ +Q WFDE   FDF  G         HYT +VW ++ +VGCG A C N K+   Y VC Y P GN   +   PY+ G PC  CP+
Sbjct:   49 TQVQREIVNKHNELRRAVS-------PPARNMLKMEWNKEAAANAQKWANQCNYRHSNPKDR-MTSLK-CGENLYMSSASSSWSQAIQSWFDEYNDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANRLYVPYEQGAPCASCPD 209
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Human
Match: CRISP3 (cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904])

HSP 1 Score: 107.457 bits (267), Expect = 1.646e-27
Identity = 65/170 (38.24%), Postives = 93/170 (54.71%), Query Frame = 1 
Query:  106 TEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNI-AYWYSQNVTEGVQFWFDEVKGFDFYTG-NCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQK--PYKVGMPCTECPE 603
            T+ + +++  HN++R  V        PPA NM +M+WN EAA  AQKWA++C + H   K+R   S +  G+N+     S + ++ +Q WFDE   FDF  G         HYT +VW ++ +VGCG A C N K+   Y VC Y P GN   +   PY+ G PC  CP+
Sbjct:   59 TQVQREIVNKHNELRRAVS-------PPARNMLKMEWNKEAAANAQKWANQCNYRHSNPKDR-MTSLK-CGENLYMSSASSSWSQAIQSWFDEYNDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANRLYVPYEQGAPCASCPD 219
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Celegans
Match: scl-5 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q18543])

HSP 1 Score: 83.1889 bits (204), Expect = 2.591e-19
Identity = 54/191 (28.27%), Postives = 85/191 (44.50%), Query Frame = 1 
Query:   97 RLTTEQKDQLLKIHNDIRIRVGHGMV----HGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQF-------WFDEVKGFDFYTGNCKKFTCL-----HYTALVWANTDMVGCGLADCSNYKMG--NMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHC 615
            + +   +  +L +HN +R R+  G        +P A++M +M+W+   A  AQ +A+KC   H  A     N Y W      YW S  +T   QF       W  E + +  ++ N    +       H T + WA T+++GCG+ +C     G   + +VC Y P GN   Q  Y  G  C++CP    C
Sbjct:   18 QFSANGQAAILNVHNTLRSRIAKGTYVAKGTAKPAASDMLKMKWDATVAASAQAYANKCPTGHSGAAGLGENLY-W------YWTSATITNIDQFGATGSAAWEKEFQDYG-WSSNTLSMSLFNTGIGHATQMAWAKTNLIGCGVKNCGKDTNGFNKVTVVCQYKPQGNYLNQNIYTSGTTCSKCPSGTSC 200
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Celegans
Match: scl-10 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q20609])

HSP 1 Score: 78.1814 bits (191), Expect = 1.834e-17
Identity = 52/185 (28.11%), Postives = 84/185 (45.41%), Query Frame = 1 
Query:  115 KDQLLKIHNDIRIRVGHG-MVHG---QPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTE---------GVQFWFDEVKGF----DFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMY-LVCNYAPGGNIGYQKPYKVGMPCTECPERFHC 615
            K+ +L  HN +R ++  G  V G   +P A+NM ++ W+      AQ ++  C   H  ++         +G+N+ +W S  VT+             W  E + F    +  T         H T + WA T+ +GCG++ CS+   G  Y +VC Y+P GN      YK G  C+ CP+  +C
Sbjct:   27 KNYILSRHNYLRSQIALGKYVAGNSTKPSASNMMKLIWDTTLETTAQDYSTGCPTGHSASRAN-------IGENMYWWTSPVVTQTDAELLGNRSANLWESEFQRFGWNGNLLTEELFNSGIGHATQMAWATTNKIGCGISKCSSDSFGTQYVVVCLYSPAGNYIGMDIYKSGETCSNCPDGTNC 204
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Celegans
Match: scl-12 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q9N5N3])

HSP 1 Score: 75.485 bits (184), Expect = 1.682e-16
Identity = 52/194 (26.80%), Postives = 88/194 (45.36%), Query Frame = 1 
Query:   94 GRLTTEQKDQLLKIHNDIRIRVGHGMVHG----QPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAY-WYSQNVTEGVQF-------WFDEVKGF----DFYTGNCKKFTCLHYTALVWANTDMVGCGLADCS-NYKMGNMY---LVCNYAPGGNIGYQKPYKVGMPCTECPERFHC 615
             + ++  +  ++K HND+R  +  G        +PPAANM++++W+   A  AQ++A+ C  DH   +          G+N+ + W S   T   +F       W  E + +     +   +       H T + WA T+ +GCG+ +C  +  M NMY   +VC Y   GN+     Y+ G  C+ CP    C
Sbjct:   16 AQFSSTAQTAIVKAHNDLRSAIALGNYDAAGTIEPPAANMRKIKWDSTVASSAQQYANTCPDDHSGTE---------YGENLYWSWSSSAPTSLDKFGVAASNSWEKEFQDYGWESTYMDADLFDSGIGHATQMAWAETNKIGCGVKNCGKDSSMNNMYKVAVVCQYDQAGNMMDSDIYQSGDTCSFCPSGSKC 200
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Celegans
Match: scl-9 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q93747])

HSP 1 Score: 74.3294 bits (181), Expect = 6.016e-16
Identity = 51/195 (26.15%), Postives = 90/195 (46.15%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVH----GQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQF-------WFDEVK--GFD--FYTGNCKKFTCLHYTALVWANTDMVGCGLADCS-NYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELCH 636
             + E +  LL +HN+ R ++  G +      +P A+ M+++ W+ +    A K+A+ C  +H    N         G++I + +S +++   Q+       W++E +  G+D   Y    ++F   H   + W  T  VGCG + C+       M +VC Y   GNI  +  Y  G  CT+CPE +    + LC 
Sbjct:   20 FSKEGQLNLLNVHNEFRSQLALGQLSFRGVKKPSASMMRKISWSKKLTNAATKFAETCPKNHSVVMN--------TGESIFWHFSSSLSTPEQYATLAPQKWWNEFETNGWDSLIYNHASQRFQIGHAVQMAWHTTSKVGCGYSKCAVGTPEQTMVVVCRYFQKGNIEGEPIYNEGETCTKCPEEYQKCPSGLCE 206
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Celegans
Match: scl-14 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q93444])

HSP 1 Score: 73.559 bits (179), Expect = 1.060e-15
Identity = 51/192 (26.56%), Postives = 85/192 (44.27%), Query Frame = 1 
Query:   97 RLTTEQKDQLLKIHNDIRIRVGHGMVHGQP----PAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIA-YWYSQNVTEGVQF-------WFDEVKGFDFYTGNCKKFTCL-----HYTALVWANTDMVGCGLADCS--NYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHC 615
            + T   +  +L +HN +R R+  G    +      A++M +M+W    A  +Q +A++C   H             VG+N+  YW S  +T   QF       W  E + +  ++ N    +       H T + WA T+++GCG+ +C      M  + +VC+Y P GN   Q  Y  G  C++CP    C
Sbjct:   18 QFTANGQAAILNVHNTLRSRIAKGTYVARGTVKHAASDMLKMKWLRSLATSSQIYANRCPTGHSNMIG--------VGENLYWYWTSGTITNIDQFGAMASAAWEKEFQDYG-WSSNTLTMSLFNSGVGHATQMAWAKTNLIGCGVKNCGMDTNGMNKVAVVCHYQPQGNYLNQNIYTSGTTCSKCPAGTSC 200
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Fly
Match: CG8483 (gene:FBgn0038126 transcript:FBtr0082782)

HSP 1 Score: 130.568 bits (327), Expect = 1.452e-35
Identity = 70/170 (41.18%), Postives = 97/170 (57.06%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--------NVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMP 585
            +T E++  +L+ HN +R  V  G   GQP A NM+++ W+DE A RAQKWAD CQF HDP  +R  N +  +GQN+A  +S         +    +Q WF+EV+ + F  G+       HY+ LVW  T +VGCG A+  +    N   VCNY PGGN+    PY+VG P
Sbjct:   32 ITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDP--HRTINRFT-MGQNLAIIWSTAPLDADDGDFPSRIQSWFNEVQKYSF--GDAWSPKTGHYSQLVWGETSLVGCGYAEYKDTSKYNKLYVCNYGPGGNVVGYNPYEVGKP 196
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Fly
Match: CG32679 (gene:FBgn0052679 transcript:FBtr0071469)

HSP 1 Score: 74.7146 bits (182), Expect = 1.015e-15
Identity = 55/185 (29.73%), Postives = 87/185 (47.03%), Query Frame = 1 
Query:  124 LLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQF------WFDEVKGFDFYTGNCKKF------TCLHYTALVWANTDMVGCGLA---DCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELC 633
            +L++HN+ R  +  G V G P A  M  M W+   A  A   A +C+  HD  +N   N+YR+ GQN++  ++++V   V        WFDE +  D  +G+ + +         H+T +V    + VGC +A   D +N +     L CNYA   N+     Y+ G   +EC    + N   LC
Sbjct:   64 ILQLHNERRNLIAGGGVSGFPSAVQMATMSWDTTLAQLAAYNALQCRMAHDECRNT--NTYRYAGQNLSILFTRSVDVAVFLRQRIAAWFDENR--DATSGDMEDYQMRGGPAIGHFTTMVNERNNRVGCAIARFTDANNVQA--TLLACNYAV-TNVVNNPVYRAGTAASECTTGRNSNYPNLC 241
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Fly
Match: Ag5r (gene:FBgn0015010 transcript:FBtr0333658)

HSP 1 Score: 70.4774 bits (171), Expect = 3.297e-14
Identity = 58/183 (31.69%), Postives = 76/183 (41.53%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIA---YWYSQNVTE----GVQFWFDEV-----KGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCS----NYKMGNMYLVCNYAPGGNIG---YQKPYKVGMPCT 591
            L++ +KD L+   N+ R  +  G+      A  M  ++WNDE A  A      CQ  HD   N   +++ W GQN+A   Y+   NVT     GV  W+DE         D Y  N       H+T LV      VGC  A  S    +YK     L CNYA    +G   Y    K    CT
Sbjct:   54 LSSAEKDALVARTNEYRNHIAGGLNANLSAACRMATIKWNDELAYLASLNVKSCQMKHDGCHNT--DAFDWSGQNLAWMGYYNPLNVTHYLEWGVDMWYDEAVYTKQAYIDAYPSNYNGPAIGHFTVLVADRNTEVGCAAATYSVSGQSYKA--FLLACNYAATNVLGIKMYSSCSKAASKCT 232
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Fly
Match: Ag5r (gene:FBgn0015010 transcript:FBtr0073937)

HSP 1 Score: 70.4774 bits (171), Expect = 3.297e-14
Identity = 58/183 (31.69%), Postives = 76/183 (41.53%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIA---YWYSQNVTE----GVQFWFDEV-----KGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCS----NYKMGNMYLVCNYAPGGNIG---YQKPYKVGMPCT 591
            L++ +KD L+   N+ R  +  G+      A  M  ++WNDE A  A      CQ  HD   N   +++ W GQN+A   Y+   NVT     GV  W+DE         D Y  N       H+T LV      VGC  A  S    +YK     L CNYA    +G   Y    K    CT
Sbjct:   54 LSSAEKDALVARTNEYRNHIAGGLNANLSAACRMATIKWNDELAYLASLNVKSCQMKHDGCHNT--DAFDWSGQNLAWMGYYNPLNVTHYLEWGVDMWYDEAVYTKQAYIDAYPSNYNGPAIGHFTVLVADRNTEVGCAAATYSVSGQSYKA--FLLACNYAATNVLGIKMYSSCSKAASKCT 232
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Fly
Match: Ag5r (gene:FBgn0015010 transcript:FBtr0305582)

HSP 1 Score: 70.4774 bits (171), Expect = 3.297e-14
Identity = 58/183 (31.69%), Postives = 76/183 (41.53%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIA---YWYSQNVTE----GVQFWFDEV-----KGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCS----NYKMGNMYLVCNYAPGGNIG---YQKPYKVGMPCT 591
            L++ +KD L+   N+ R  +  G+      A  M  ++WNDE A  A      CQ  HD   N   +++ W GQN+A   Y+   NVT     GV  W+DE         D Y  N       H+T LV      VGC  A  S    +YK     L CNYA    +G   Y    K    CT
Sbjct:   54 LSSAEKDALVARTNEYRNHIAGGLNANLSAACRMATIKWNDELAYLASLNVKSCQMKHDGCHNT--DAFDWSGQNLAWMGYYNPLNVTHYLEWGVDMWYDEAVYTKQAYIDAYPSNYNGPAIGHFTVLVADRNTEVGCAAATYSVSGQSYKA--FLLACNYAATNVLGIKMYSSCSKAASKCT 232
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Zebrafish
Match: r3hdml (R3H domain containing-like [Source:ZFIN;Acc:ZDB-GENE-090313-275])

HSP 1 Score: 109.768 bits (273), Expect = 1.031e-28
Identity = 63/186 (33.87%), Postives = 100/186 (53.76%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSN-YKMGNMY-----LVCNYAPGGNIGYQKPYKVGMPCTECPERF--HCNGNE 627
            ++ +    LL  HN +R +V        PPAANM+ M W++  A  A+ WA +C ++H P      +  + +GQN++    +  ++ + V+ W+DE   F  Y   C    C HYT +VWA ++ +GC +  CS+ +  G+M+     LVCNYA  GN   + PYK+G PC+ CP  +   CN N+
Sbjct:   61 ISGKDMTALLDYHNRVRSQVF-------PPAANMEYMVWDERLAKSAEFWASQCIWEHGP-----HHFLQHIGQNLSIISGRYKSIIDLVKSWYDERHSFS-YPSRCSGSVCTHYTQMVWAASNKIGCAIKKCSDIFVFGSMWKQATLLVCNYAIKGNWVGEAPYKIGRPCSACPSSYGGSCNKNQ 233
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Zebrafish
Match: r3hdml (R3H domain containing-like [Source:ZFIN;Acc:ZDB-GENE-090313-275])

HSP 1 Score: 109.768 bits (273), Expect = 1.031e-28
Identity = 63/186 (33.87%), Postives = 100/186 (53.76%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSN-YKMGNMY-----LVCNYAPGGNIGYQKPYKVGMPCTECPERF--HCNGNE 627
            ++ +    LL  HN +R +V        PPAANM+ M W++  A  A+ WA +C ++H P      +  + +GQN++    +  ++ + V+ W+DE   F  Y   C    C HYT +VWA ++ +GC +  CS+ +  G+M+     LVCNYA  GN   + PYK+G PC+ CP  +   CN N+
Sbjct:   61 ISGKDMTALLDYHNRVRSQVF-------PPAANMEYMVWDERLAKSAEFWASQCIWEHGP-----HHFLQHIGQNLSIISGRYKSIIDLVKSWYDERHSFS-YPSRCSGSVCTHYTQMVWAASNKIGCAIKKCSDIFVFGSMWKQATLLVCNYAIKGNWVGEAPYKIGRPCSACPSSYGGSCNKNQ 233
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Zebrafish
Match: pi15a (peptidase inhibitor 15a [Source:NCBI gene;Acc:561978])

HSP 1 Score: 108.997 bits (271), Expect = 2.673e-28
Identity = 68/186 (36.56%), Postives = 100/186 (53.76%), Query Frame = 1 
Query:  109 EQKDQL--LKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM-GNM-----YLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
             Q D L  L  HN +R +V        PPA+NM+ M W+D  A  A++WA  C ++H P      N  R++GQN++    +  ++ + V+ W DEVK + F Y  +C            C HYT +VWA ++ VGC +  C N  + G++     YLVCNY+P GN   + PYKVG+PC+ CP  +
Sbjct:   65 SQNDMLAILDYHNKVRGKVF-------PPASNMEYMVWDDTLAKTAEQWASTCIWEHGPR-----NLLRFLGQNLSVRTGRYRSILQLVKPWHDEVKDYSFPYPRDCNPRCPLKCYGPMCTHYTQMVWATSNKVGCAINTCHNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSMCPPSY 238
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Zebrafish
Match: pi15b (peptidase inhibitor 15b [Source:ZFIN;Acc:ZDB-GENE-070912-590])

HSP 1 Score: 104.76 bits (260), Expect = 7.085e-27
Identity = 62/179 (34.64%), Postives = 94/179 (52.51%), Query Frame = 1 
Query:  124 LLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYS--QNVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKMGN------MYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            +L  HN +R  V        PPAANM+ M W+D  A  A+ WA  C ++H P         R++GQN++      +++ + V+ W+DEV+ + F Y  +C            C HYT +VWA+++ VGC +  C N  +         YLVCNY+P GN   + PY+VG+PC+ CP  +
Sbjct:   54 ILDYHNKVRANVF-------PPAANMEYMLWDDGLARSAEAWAATCIWEHGPPY-----LLRYLGQNLSVRTGNYRSILQLVKPWYDEVRDYMFPYPRDCNPHCPMRCYGPMCTHYTQMVWASSNRVGCAIQTCFNMVVWGAVWREATYLVCNYSPKGNWIGEAPYRVGVPCSACPPSY 220
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Zebrafish
Match: pi15b (peptidase inhibitor 15b [Source:ZFIN;Acc:ZDB-GENE-070912-590])

HSP 1 Score: 104.76 bits (260), Expect = 8.498e-27
Identity = 62/179 (34.64%), Postives = 94/179 (52.51%), Query Frame = 1 
Query:  124 LLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYS--QNVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            +L  HN +R  V        PPAANM+ M W+D  A  A+ WA  C ++H P         R++GQN++      +++ + V+ W+DEV+ + F Y  +C            C HYT +VWA+++ VGC +  C N  +         YLVCNY+P GN   + PY+VG+PC+ CP  +
Sbjct:   69 ILDYHNKVRANVF-------PPAANMEYMLWDDGLARSAEAWAATCIWEHGPPY-----LLRYLGQNLSVRTGNYRSILQLVKPWYDEVRDYMFPYPRDCNPHCPMRCYGPMCTHYTQMVWASSNRVGCAIQTCFNMVVWGAVWREATYLVCNYSPKGNWIGEAPYRVGVPCSACPPSY 235
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Xenopus
Match: pi15 (peptidase inhibitor 15 [Source:NCBI gene;Acc:100489915])

HSP 1 Score: 108.997 bits (271), Expect = 2.835e-28
Identity = 65/199 (32.66%), Postives = 104/199 (52.26%), Query Frame = 1 
Query:   94 GRLTTEQKDQLLKIHNDIRIRVGHGMVHGQ--PPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF--HCNGNE 627
             ++   ++ + +  ++ I I   H  V G+  PPAANM+ M W++  A  A+ WA  C +DH P+   KF     +GQN++    +  ++ + V+ W+DEVK + F Y   C            C HYT +VWA T+ +GC +  C N  +        +YLVCNY+P GN   + PY +G+PC+ CP  +   C+ N+
Sbjct:   51 AKVPKARRKRYISQNDMIAIVEYHNQVRGKVFPPAANMEYMVWDENLAKLAEAWAATCIWDHGPSYLLKF-----LGQNLSVRTGRYKSILQLVKPWYDEVKDYAFPYPQECNPRCPLRCYGPMCTHYTQMVWATTNRIGCAIHTCHNMNVWGAVWRRAVYLVCNYSPKGNWIGEAPYTIGVPCSACPPSYGGSCSDNQ 244
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Xenopus
Match: R3HDML (R3H domain containing-like [Source:NCBI gene;Acc:100492715])

HSP 1 Score: 107.457 bits (267), Expect = 1.031e-27
Identity = 59/187 (31.55%), Postives = 97/187 (51.87%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYS--QNVTEGVQFWFDEVKGFDFY---------TGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGN------MYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            ++      LL  HN +R +V        PPAANM+ M W++  A  A+ WA++C++DH P +       R++GQN++      +++ + V+ W+DE + + F             C    C HYT +VWA+++ +GC +  C+N  +         YLVCNY+  GN   + PYK+G PC+ CP  +
Sbjct:   53 ISPRDMSALLDYHNQVRSKVF-------PPAANMEYMVWDERLAKSAESWANQCKWDHGPNQ-----LMRYIGQNLSVHSGRYRSIVDLVKGWYDERQHYSFPHPRECNPSCPNKCTGAVCTHYTQMVWASSNRIGCAVNICTNINVWGSTWRQASYLVCNYSIKGNWIGEAPYKLGRPCSACPPSY 227
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Xenopus
Match: R3HDML (R3H domain containing-like [Source:NCBI gene;Acc:100492715])

HSP 1 Score: 107.071 bits (266), Expect = 1.289e-27
Identity = 59/187 (31.55%), Postives = 97/187 (51.87%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYS--QNVTEGVQFWFDEVKGFDFY---------TGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGN------MYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            ++      LL  HN +R +V        PPAANM+ M W++  A  A+ WA++C++DH P +       R++GQN++      +++ + V+ W+DE + + F             C    C HYT +VWA+++ +GC +  C+N  +         YLVCNY+  GN   + PYK+G PC+ CP  +
Sbjct:   58 ISPRDMSALLDYHNQVRSKVF-------PPAANMEYMVWDERLAKSAESWANQCKWDHGPNQ-----LMRYIGQNLSVHSGRYRSIVDLVKGWYDERQHYSFPHPRECNPSCPNKCTGAVCTHYTQMVWASSNRIGCAVNICTNINVWGSTWRQASYLVCNYSIKGNWIGEAPYKLGRPCSACPPSY 232
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Xenopus
Match: crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:NCBI gene;Acc:613091])

HSP 1 Score: 110.153 bits (274), Expect = 2.687e-27
Identity = 71/193 (36.79%), Postives = 102/193 (52.85%), Query Frame = 1 
Query:  115 KDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIA-YW--YSQNVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCN-GNELCH 636
            K++++++HN +R     G VH  P A+NM+ M W+DE    A+ WA++C ++H P           +GQN+A +W  Y Q     VQ W+DEVK + + Y   C  +         C HYT +VWA T  VGC +  C    +        +YLVCNY+P GN   + PYK G PC+ECP  +  N  N LC+
Sbjct:   57 KEEIIQLHNKLR-----GQVH--PSASNMEYMTWDDELEKSAEAWAEECIWEHGPTA-----LLMSIGQNLAVHWGRYRQPAYH-VQSWYDEVKDYTYPYPHECNPYCPERCSGPMCTHYTQIVWATTTKVGCAVNVCKRMNVWGDIWENAVYLVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGNCQNNLCY 236
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Xenopus
Match: crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:NCBI gene;Acc:613091])

HSP 1 Score: 110.153 bits (274), Expect = 3.239e-27
Identity = 71/193 (36.79%), Postives = 102/193 (52.85%), Query Frame = 1 
Query:  115 KDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIA-YW--YSQNVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCN-GNELCH 636
            K++++++HN +R     G VH  P A+NM+ M W+DE    A+ WA++C ++H P           +GQN+A +W  Y Q     VQ W+DEVK + + Y   C  +         C HYT +VWA T  VGC +  C    +        +YLVCNY+P GN   + PYK G PC+ECP  +  N  N LC+
Sbjct:   57 KEEIIQLHNKLR-----GQVH--PSASNMEYMTWDDELEKSAEAWAEECIWEHGPTA-----LLMSIGQNLAVHWGRYRQPAYH-VQSWYDEVKDYTYPYPHECNPYCPERCSGPMCTHYTQIVWATTTKVGCAVNVCKRMNVWGDIWENAVYLVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGNCQNNLCY 236
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Mouse
Match: Crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:MGI Symbol;Acc:MGI:1926142])

HSP 1 Score: 119.013 bits (297), Expect = 1.570e-30
Identity = 70/211 (33.18%), Postives = 107/211 (50.71%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG--VQFWFDEVKGFDFYTGN---------CKKFTCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNG-NELCH*IKEKSLKTKYNLL 678
            +    + ++L +HN +R +V        PPA+NM+ M W++E    A  WA +C ++H PA        R +GQN+A  + +  + G  VQ W+DEVK + +   +         C    C HYT +VWA T+ +GC +  C N  +        +YLVCNY+P GN   + PYK G PC+ECP  +     N LCH  K    K + +++
Sbjct:   51 IPMSDRQEILMLHNKLRGQV-------YPPASNMEHMTWDEELERSAAAWAHRCLWEHGPA-----GLLRSIGQNLAVHWGRYRSPGFHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCLNNLCHREKPHKHKPEVDMM 249
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Mouse
Match: Crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:MGI Symbol;Acc:MGI:1926142])

HSP 1 Score: 119.013 bits (297), Expect = 1.570e-30
Identity = 70/211 (33.18%), Postives = 107/211 (50.71%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG--VQFWFDEVKGFDFYTGN---------CKKFTCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNG-NELCH*IKEKSLKTKYNLL 678
            +    + ++L +HN +R +V        PPA+NM+ M W++E    A  WA +C ++H PA        R +GQN+A  + +  + G  VQ W+DEVK + +   +         C    C HYT +VWA T+ +GC +  C N  +        +YLVCNY+P GN   + PYK G PC+ECP  +     N LCH  K    K + +++
Sbjct:   51 IPMSDRQEILMLHNKLRGQV-------YPPASNMEHMTWDEELERSAAAWAHRCLWEHGPA-----GLLRSIGQNLAVHWGRYRSPGFHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCLNNLCHREKPHKHKPEVDMM 249
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Mouse
Match: Crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:MGI Symbol;Acc:MGI:1926142])

HSP 1 Score: 116.316 bits (290), Expect = 1.199e-29
Identity = 69/197 (35.03%), Postives = 103/197 (52.28%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG--VQFWFDEVKGFDFY-----TGNCKKF----TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNG-NELCH 636
            +    + ++L +HN +R +V        PPA+NM+ M W++E    A  WA +C ++H PA        R +GQN+A  + +  + G  VQ W+DEVK + +      T  C++      C HYT +VWA T+ +GC +  C N  +        +YLVCNY+P GN   + PYK G PC+ECP  +     N LCH
Sbjct:   51 IPMSDRQEILMLHNKLRGQV-------YPPASNMEHMTWDEELERSAAAWAHRCLWEHGPA-----GLLRSIGQNLAVHWGRYRSPGFHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCLNNLCH 235
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Mouse
Match: Pi15 (peptidase inhibitor 15 [Source:MGI Symbol;Acc:MGI:1934659])

HSP 1 Score: 110.923 bits (276), Expect = 6.340e-29
Identity = 64/179 (35.75%), Postives = 96/179 (53.63%), Query Frame = 1 
Query:  124 LLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            +L  HN +R +V        PPAANM+ M W++  A  A+ WA  C +DH P+   +F     +GQN++    +  ++ + V+ W+DEVK + F Y  +C            C HYT +VWA ++ +GC +  C N  +        +YLVCNYAP GN   + PYKVG+PC+ CP  +
Sbjct:   81 ILDYHNQVRGKVF-------PPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRF-----LGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSY 247
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Mouse
Match: Pi16 (peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:1921366])

HSP 1 Score: 108.227 bits (269), Expect = 3.071e-28
Identity = 64/185 (34.59%), Postives = 101/185 (54.59%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDFYTGNCK-KFTCLHYTALVWANTDMVGCGLADCSNYK---MGNMYL-VCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELC 633
            LT ++K  ++ +HN  R +V        PPA++M QM+W+DE A  A+ +A KC + H+  + R+       G+N+     +  +V   V  W +E + ++F T  C     C HYT +VW+ T+ +GCG   C   +     N++L VCNY P GN+  +KPY+ G PC++CP  + C  N LC
Sbjct:   30 LTEDEKQTMVDLHNQYRAQV-------SPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRR-------GENLFAITDEGMDVPLAVGNWHEEHEYYNFSTATCDPNQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCE-NSLC 199
[Close]
BLAST of SCP domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPU1|VA576_SCODE (Scoloptoxin SSD976 OS=Scolopendra dehaani OX=2609776 PE=1 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 8.062e-35
Identity = 71/172 (41.28%), Postives = 91/172 (52.91%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNI-AYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTC-----LHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTEC 597
            L    K  +L +HN  R  V +G   GQP AANMK++ WNDE A  AQ+ A+ C F+H     RK   Y ++G+NI    Y   +   V  W+DEVK  D      K F+       HYT +VWANT+ +GCGL   S+    N YL C Y PGGN   Q  YK G P ++C
Sbjct:   31 LDANMKKMILDLHNKKRQIVANGQQSGQPSAANMKELHWNDEIAANAQRSAETCVFEHTAKSLRKTTKYSYLGENIYKGSYPDPIPRSVNAWYDEVK--DVTPAVVKSFSSGGPMIGHYTQMVWANTEALGCGLVTASDR---NSYLFCQYGPGGNYRSQPIYKQGPPASDC 197
[Close]
BLAST of SCP domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPV2|VA558_SCODE (Scoloptoxin SSD558 OS=Scolopendra dehaani OX=2609776 PE=1 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 9.383e-34
Identity = 70/172 (40.70%), Postives = 90/172 (52.33%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNI-AYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTC-----LHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTEC 597
            L    K  +L +HN  R  V +G   GQP AANMK++ WNDE A  AQ+ A+ C F+H     RK   Y ++G+NI    Y   +   V  W+DEVK  D      K F+       HYT +VWANT+ + CGL   S+    N YL C Y PGGN   Q  YK G P ++C
Sbjct:   31 LDANMKKMILDLHNKKRQIVANGQQSGQPSAANMKELHWNDEIAANAQRSAETCVFEHTAKSLRKTTKYSYLGENIYKGSYPDPIPRSVNAWYDEVK--DVTPAVVKSFSSGGPMIGHYTQMVWANTEALDCGLVTASDR---NSYLFCQYGPGGNYRSQPIYKQGPPASDC 197
[Close]
BLAST of SCP domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPU2|VA543_SCODE (Scoloptoxin SSD43 OS=Scolopendra dehaani OX=2609776 PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 9.084e-32
Identity = 65/175 (37.14%), Postives = 96/175 (54.86%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNI-AYWYSQNVTEGVQFWFDEVK--------GFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTEC 597
            L  + K+++LK HN++R +V +G   GQP A+NMKQ++WNDE A  AQ+ A++C F H   + RK   Y   G+++ A  +S  +   V  W++EV+         +D+Y G        HY  LVWA T+ +GCG A  +    G  Y+ C+YAP G    Q  YK G P + C
Sbjct:   30 LDKKMKNKILKHHNELRQKVANGQERGQPTASNMKQLRWNDELAANAQRAAERCIFQHTSDEGRKTTKYGVAGESMYAGTFSNPLKTAVDMWYEEVRDVNPSILDSYDYYPGA----VIGHYIQLVWAETEAIGCGYAKSA--ADGESYVFCHYAPHGLFPQQSVYKRGSPASAC 198
[Close]
BLAST of SCP domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPU0|VA552_SCODE (Scoloptoxin SSD552 OS=Scolopendra dehaani OX=2609776 PE=1 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 1.301e-31
Identity = 68/172 (39.53%), Postives = 90/172 (52.33%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNI-AYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFT-----CLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTEC 597
            L    K  +L +HN  R  V +G   GQP AANMK++ W+DE    AQ+ A+ C F H     RK + Y ++G+N+    Y   +   V  W+DEVK  D      K F+       HYT +VWANT+ +GCGL   S+   G  YL C Y PGGN   Q+ YK G P + C
Sbjct:   31 LDANMKKMILDLHNKKRQIVANGQQSGQPLAANMKELHWDDEIEAIAQRSAETCVFKHTAKSLRKSSKYSYLGENVYKGGYPDPIPRSVNKWYDEVK--DVTPAVVKSFSDDGPMIGHYTQMVWANTEALGCGLVTASD---GTSYLFCQYGPGGNYPGQQIYKQGPPGSGC 197
[Close]
BLAST of SCP domain-containing protein vs. UniProt/SwissProt
Match: sp|Q32LB5|GPRL1_BOVIN (GLIPR1-like protein 1 OS=Bos taurus OX=9913 GN=GLIPR1L1 PE=1 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 1.010e-29
Identity = 62/168 (36.90%), Postives = 91/168 (54.17%), Query Frame = 1 
Query:  118 DQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFN---SYRWVGQNIAYWYSQNVTEGVQF----WFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNY-KMGNMYLVCNYAPGGNIGYQKPYKVGMPCTEC 597
            ++ L++HN+ R  V        PPAA+MK M W++  A  A+ WA KC+F H+   ++ F    ++++ G+N+  W         +F    W+DE K +DF T +C +  C HYT +VWA +  VGC +A C N     +  LVCNYAP GN     PY  G PC+ C
Sbjct:   36 EECLRLHNEARTNVS-------PPAADMKYMSWDEALAKTAEAWAKKCKFIHNSCSSKSFKCHPTFQYAGENL--WLGPLTISAAKFAINMWYDERKFYDFNTRSCSQ-VCGHYTQVVWAYSYKVGCAVAVCPNLGSPDSALLVCNYAPAGNYPNMSPYTNGTPCSMC 193
[Close]
BLAST of SCP domain-containing protein vs. TrEMBL
Match: A0A1I8HU24 (SCP domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002706g1 PE=3 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 3.928e-39
Identity = 75/179 (41.90%), Postives = 103/179 (57.54%), Query Frame = 1 
Query:   97 RLTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELC 633
            RL+  QK   LK HN +R +   G   GQP A+NM ++ W+D     A +W  KC+  HD A++R+   + WVGQN A  +S++ T  V+ WF+E K +++Y  +C K  C HYT +VWA T  VGCG+A C  Y     ++VCNYA GGN   + PY  G P + C  RF    N LC
Sbjct:   23 RLSQSQKMAFLKEHNRLRAQTAKGHTRGQPSASNMAELVWDDRLMRSANRWVRKCRVGHDRARDRRLPGFSWVGQNWAGGHSRDFTRYVRMWFNEYKYYNYYRKSCSK-VCGHYTQVVWAKTTRVGCGVARCGRYP---YHVVCNYATGGNFNNEFPYARGRPASRCGRRFRRRRNGLC 197
[Close]
BLAST of SCP domain-containing protein vs. TrEMBL
Match: C1LHZ3 (GLIPR1-like protein 1 OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 3.546e-37
Identity = 66/162 (40.74%), Postives = 98/162 (60.49%), Query Frame = 1 
Query:   94 GRLTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVG 579
            G +  + + +LL +HN +R  + +G + GQP A ++K ++WN E   +AQ  +D+C+  HD    RK   +  VGQN A   S++V  G Q W DE K +D+YT  C+   C HYT +VW +T  VGCG+ DC N+  G + +VCNY PGGN   ++PYK+ 
Sbjct:   25 GLMDDKMRKELLTLHNTVRAALRNGRLTGQPRAISIKPLKWNMELESKAQSLSDECRVGHDTYDARKTPEFSLVGQNWAG--SKDVKTGFQMWLDEYKNYDYYTRTCRMGQCGHYTQIVWEDTTDVGCGVTDCPNFIYG-LSIVCNYGPGGNYAGREPYKIA 183
[Close]
BLAST of SCP domain-containing protein vs. TrEMBL
Match: A0A564YFQ7 (SCP domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS5585 PE=3 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 6.137e-37
Identity = 68/159 (42.77%), Postives = 98/159 (61.64%), Query Frame = 1 
Query:   94 GRLTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPY 570
            GRL+ + K +LL + N  R  V  G V  QP ++ ++ ++WN E    AQ+ AD+C+F HD + +RK   + WVGQNIA  YS ++ + V+ WF+E K +++    C    C HYT LVWANT  VGCG++ C+      +++VCNY PGGN   QKPY
Sbjct:   47 GRLSKD-KQELLDLQNQYRREVAAGRVPNQPASSKIRDLKWNTELEASAQRHADRCRFQHDSSDDRKTAEFWWVGQNIA--YSSSIAQNVKMWFEEHKDYNYSHNYCSG-VCGHYTQLVWANTTDVGCGVSKCNFSGFNAVFVVCNYGPGGNFNNQKPY 201
[Close]
BLAST of SCP domain-containing protein vs. TrEMBL
Match: A0A1I8HQH6 (SCP domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027161g1 PE=3 SV=1)

HSP 1 Score: 140.198 bits (352), Expect = 1.282e-36
Identity = 74/178 (41.57%), Postives = 94/178 (52.81%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELC 633
            LT EQK  +L  HN +R R   G+V  QP AANM  ++W+D     A  W  +C   HD   +R    Y WVGQN A  YS N +  V  WF E K + F T +C    C HYT +VWA T +VGCG++ CSNY      +VCNYA GGN   + PY  G   ++C   +      LC
Sbjct:   25 LTAEQKQAILDAHNVLRARTAMGLVGNQPKAANMPALEWDDRLMDSANNWVKQCVAGHDSGSDRALTGYSWVGQNWAGGYSGNFSYYVDLWFREYKDYTFATKSCSAV-CGHYTQVVWAKTTLVGCGVSRCSNYPYT---IVCNYATGGNYNGEYPYVSGDDASQCNGEYVFKQRGLC 198
[Close]
BLAST of SCP domain-containing protein vs. TrEMBL
Match: A0A094ZX17 (GLIPR1-like protein 1 (Fragment) OS=Schistosoma haematobium OX=6185 GN=MS3_07294 PE=3 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 1.376e-36
Identity = 65/161 (40.37%), Postives = 99/161 (61.49%), Query Frame = 1 
Query:   94 GRLTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKV 576
             +L    +++LL +HN  R  V +G + GQP A ++K ++WN E   +AQ  +D+C+  HD   +RK  ++++VGQN A   ++++  G Q W DE K +DFYT  C+   C HYT LVW +T  VGCG+ +C N+  G + +VCNY PGGN   + PY+ 
Sbjct:   24 AQLDDAMRNELLALHNKARQSVQNGQLVGQPIAVSIKPLKWNVELETKAQILSDQCRVGHDTNADRKIPAFQYVGQNWAG--AKDINTGFQLWLDEYKNYDFYTRTCRMGQCGHYTQLVWEDTTDVGCGVTNCPNFPYG-LSIVCNYGPGGNYVGRSPYRT 181
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Cavefish
Match: r3hdml (R3H domain containing like [Source:NCBI gene;Acc:103046222])

HSP 1 Score: 116.316 bits (290), Expect = 2.209e-31
Identity = 68/186 (36.56%), Postives = 100/186 (53.76%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYS--QNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSN-YKMGNMY-----LVCNYAPGGNIGYQKPYKVGMPCTECPERF--HCNGNE 627
            +++     LL+ HN +R +V        PPAANM+ M W++  A  A+ WA +C +DH P+   K+     +GQN++      ++V E V+ W DE   F  Y   C    C HYT +VWA+T+ +GC +  CSN Y  G+ +     LVCNY+  GN   + PYK G PC+ CP  +   CN N+
Sbjct:   62 VSSRDMTALLEYHNRVRSQVF-------PPAANMEYMVWDERLAKSAESWASQCIWDHGPSHVMKY-----MGQNLSISSGRYRSVIELVRSWHDEKNSFS-YPNRCTGSVCSHYTQMVWASTNRIGCAINRCSNMYVFGSTWKQATLLVCNYSIKGNWVGEAPYKTGKPCSACPSVYGGSCNKNQ 234
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Cavefish
Match: pi15a (peptidase inhibitor 15-A-like [Source:NCBI gene;Acc:103031459])

HSP 1 Score: 115.161 bits (287), Expect = 8.332e-31
Identity = 69/190 (36.32%), Postives = 105/190 (55.26%), Query Frame = 1 
Query:   97 RLTTEQKDQL--LKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM-GNM-----YLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            R    Q+D L  L+ HN +R +V        PPA+NM+ M W+D  A RA++WA  C ++H P      N  R++GQN++    +  ++ + V+ W+DEVK + F Y  +C            C HYT +VWA ++ +GC +  C N  + G++     YLVCNY+P GN   + PYKVG+PC+ CP  +
Sbjct:   60 RRAISQEDMLAILQYHNKVRGKVF-------PPASNMEYMVWDDSLAKRAEEWASTCLWEHGPR-----NLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYSFPYPRDCNPRCPLKCYGPMCTHYTQMVWATSNKIGCAIHTCYNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSMCPPSY 237
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Cavefish
Match: pi15a (peptidase inhibitor 15-A-like [Source:NCBI gene;Acc:103031459])

HSP 1 Score: 114.775 bits (286), Expect = 1.308e-30
Identity = 69/190 (36.32%), Postives = 105/190 (55.26%), Query Frame = 1 
Query:   97 RLTTEQKDQL--LKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM-GNM-----YLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            R    Q+D L  L+ HN +R +V        PPA+NM+ M W+D  A RA++WA  C ++H P      N  R++GQN++    +  ++ + V+ W+DEVK + F Y  +C            C HYT +VWA ++ +GC +  C N  + G++     YLVCNY+P GN   + PYKVG+PC+ CP  +
Sbjct:   67 RRAISQEDMLAILQYHNKVRGKVF-------PPASNMEYMVWDDSLAKRAEEWASTCLWEHGPR-----NLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYSFPYPRDCNPRCPLKCYGPMCTHYTQMVWATSNKIGCAIHTCYNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSMCPPSY 244
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Cavefish
Match: crispld1a (cysteine-rich secretory protein LCCL domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-090612-1])

HSP 1 Score: 107.071 bits (266), Expect = 2.001e-26
Identity = 64/188 (34.04%), Postives = 96/188 (51.06%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNV---TEGVQFWFDEVKGFDF-YTGNCKK---FTCL-----HYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            +++     +L +HN +R +V        PP++NM+ M W+ E    A++WA+ C ++H PA          +GQN+   + ++V   T  VQ W+DEVK + F Y   C     FTC      HYT LVWA +  +GC +  C +  +        +YLVCNY+P GN     PYK G PC+ CP  +
Sbjct:   57 ISSSDMQAILDLHNKLRAQV-------YPPSSNMEYMVWDTELERSAEEWAETCLWEHGPA-----GLLPQIGQNLGVHWGRSVPAPTSHVQAWYDEVKDYSFPYPQECNPHCPFTCTGPVCTHYTQLVWATSSRIGCAINVCYDMNVWGQIWAKAVYLVCNYSPKGNWWGHAPYKHGSPCSACPPSY 232
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Cavefish
Match: crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-130131-1])

HSP 1 Score: 107.071 bits (266), Expect = 2.299e-26
Identity = 63/182 (34.62%), Postives = 94/182 (51.65%), Query Frame = 1 
Query:  115 KDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG--VQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            ++++L +HN +R  V        P A+NM+ M W+DE    A  WA++CQ++H P      +    +GQN+A  + +  +    VQ W+DEVK + + Y   C  +         C HYT LVWA T  VGC +  CS   +        +YLVCNY+P GN   + PY  G PC++CP  +
Sbjct:   61 REEILALHNKLREGV-------YPTASNMEYMVWDDELERSATHWAEQCQWEHGPQ-----DLLMSIGQNLAVHWGRYRSPAYHVQAWYDEVKDYTYPYPHECNPWCPERCSGPMCTHYTQLVWATTSRVGCAVHTCSRMNVWGEIWENAIYLVCNYSPKGNWIGEAPYAHGRPCSQCPPSY 230
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000374.1 (pep scaffold:Pmarinus_7.0:GL476650:75849:87118:-1 gene:ENSPMAG00000000334.1 transcript:ENSPMAT00000000374.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.834 bits (255), Expect = 6.309e-26
Identity = 65/216 (30.09%), Postives = 104/216 (48.15%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQN--VTEGVQFWFDEVKGFDFYTG---------NCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGN------MYLVCNYAPGGNIGYQKPYKVGMPCTECPERF--HCNGNELCH*IKEKSLKTKYNLLAFRI 690
            +  +++  L + HN +R  V        P AA+M+ M W+ E A  A+ WA +C++ H P+     +    +GQN+A +      +   VQ WFDE + + +             C+   C HYT LVWA +  VGC +  C +  + +      +YLVCNY+P GN   + PY+ G PC+ CP R+   C G  LC+ +  +  +    L  F +
Sbjct:    1 IADDERRALTEYHNRLRASV-------HPQAADMEHMSWDWELAGMAEAWAKQCKWGHGPS-----DQLDAIGQNLAVYVGSERPLAYHVQAWFDEEEWYQYPEEKECSPECPHTCRGPICTHYTQLVWAESRRVGCAVHTCLDISVWDAVWPYALYLVCNYSPKGNWIGEAPYRQGTPCSRCPPRYGGSCRGG-LCYQVTIRRPQRLDELSQFGV 203
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Sea Lamprey
Match: CRISP3 (cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904])

HSP 1 Score: 89.3521 bits (220), Expect = 9.332e-22
Identity = 57/167 (34.13%), Postives = 82/167 (49.10%), Query Frame = 1 
Query:  124 LLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVT--EGVQFWFDEV--KGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADC-SNYKMGNMYLVCNYAPGGNIGYQ--KPYKVGMPCTECPE 603
            ++ +HND+R  V        P A NM QM W  EA + A  WA+ C F H P   RK   +   G+NI +  S   T    ++ W++EV   GF +  G+       HYT LVW N+  +GC +  C  N  +     VC+Y P GN+  +  +PY +G  C  CP+
Sbjct:   47 IVDLHNDLRRNV-------TPSAGNMLQMMWKKEAYLNALSWANNCTFGHSPDARRKTTQWT-CGENI-FMSSAPFTWNYAIRDWYNEVISPGFQYDVGSTTTGAVGHYTQLVWYNSFQLGCAVNYCPKNPGVAKYLYVCHYCPMGNLNTRINRPYDLGTSCASCPK 204
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002250.1 (pep scaffold:Pmarinus_7.0:GL477299:1626:22672:-1 gene:ENSPMAG00000002049.1 transcript:ENSPMAT00000002250.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 9.127e-21
Identity = 59/176 (33.52%), Postives = 82/176 (46.59%), Query Frame = 1 
Query:  130 KIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTE-GVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKMGN------MYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            ++HN +R     G VH  PP++NM+ M W  +    A ++  +C     P     F     +GQ   +W S       VQ W+DE K + + Y   C  +         C HYT LVWA T+ VGC +  C N  +        +YLVCNY+P GN     PYK G  C+ECP  +
Sbjct:    1 ELHNKLR-----GEVH--PPSSNMEYMAWVKKLIKEAARYPGRCLRLMQPMAMIHF-----LGQ--PHWLSHRPPSFHVQAWYDEAKDYQYPYEQECNPWCPFRCNGAVCTHYTQLVWATTNRVGCAINTCYNMNVWGQIWEKAVYLVCNYSPKGNWIGLSPYKSGRACSECPPSY 162
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Sea Lamprey
Match: CLEC18A (C-type lectin domain family 18 member A [Source:HGNC Symbol;Acc:HGNC:30388])

HSP 1 Score: 55.0694 bits (131), Expect = 3.326e-9
Identity = 42/163 (25.77%), Postives = 62/163 (38.04%), Query Frame = 1 
Query:  124 LLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWA------------DKCQFDHDPA-------KNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCK-KFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNI 552
            L  +HN +R  V       QP AANM++M+W+D  A  A +WA               +    P                  V  + A   + +    +  WF E + +D+    C    TC HYT +VWA+   VGC    C +         C Y PG ++
Sbjct:   53 LESLHNKLRATV-------QPSAANMEKMEWDDSLAQVAHEWAAVACENPRAAEGTSAEIPEKPGIQGTGAGGRGGGQRRLGVNLHRAPHGATSFASVLASWFSEGQNYDYARPGCAHNRTCRHYTQMVWASASRVGCAKRWCRDPGSRVEAFACVYLPGNDV 208
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Sea Lamprey
Match: CRISP2 (cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024])

HSP 1 Score: 48.521 bits (114), Expect = 1.333e-7
Identity = 33/97 (34.02%), Postives = 46/97 (47.42%), Query Frame = 1 
Query:  355 EGVQFWFDE--VKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIG--YQKPYKVGMPCTECPERFHCNGNELC 633
            + V  W++E  V GF F  G        HYT +VW ++  +GC +  C       +Y VC+Y P GN+     +PY  G PC  CP       N+LC
Sbjct:   16 DAVLDWYNEAEVPGFIFGKGPAAPGDIGHYTQVVWYSSFQLGCAVNYCPEAIYKYVY-VCHYCPAGNLNTRLSRPYNEGSPCRSCPNDCE---NDLC 108
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Yeast
Match: PRY3 (Cell wall-associated protein involved in export of acetylated sterols; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p [Source:SGD;Acc:S000003614])

HSP 1 Score: 58.9214 bits (141), Expect = 1.174e-10
Identity = 36/114 (31.58%), Postives = 55/114 (48.25%), Query Frame = 1 
Query:  208 MQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGN 549
            + W+D  A  AQ +AD  Q+D           Y   G+N+A  Y+   T  V  W+ E+  +++      + T  H+T +VW +T  +GCG   C      N Y+VC+Y P GN
Sbjct:   46 LTWSDTLATYAQNYAD--QYDCSGVLTHSDGPY---GENLALGYTD--TGAVDAWYGEISKYNYSNPGFSESTG-HFTQVVWKSTAEIGCGYKYCGT--TWNNYIVCSYNPPGN 149
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Yeast
Match: PRY2 (Sterol binding protein involved in the export of acetylated sterols; secreted glycoprotein and member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); sterol export function is redundant with that of PRY1; may be involved in detoxification of hydrophobic compounds; PRY2 has a paralog, PRY1, that arose from the whole genome duplication [Source:SGD;Acc:S000001721])

HSP 1 Score: 53.9138 bits (128), Expect = 4.776e-9
Identity = 35/116 (30.17%), Postives = 59/116 (50.86%), Query Frame = 1 
Query:  205 QMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNI 552
             + W+D  A  AQ +AD     +D + N   +   + G+N+A  Y    T  V  W++E+  +D+      + +  H+T +VW  T  VGCGL  C   + G+ Y++C+Y   GN+
Sbjct:  212 SLTWSDTLATYAQNYADS----YDCSGNLVHSGGPY-GENLALGY--GTTGSVDAWYNEITSYDYSNPGFSE-SAGHFTQVVWKGTSEVGCGLKSCGG-EWGD-YIICSYKAAGNV 317
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Yeast
Match: PRY1 (Sterol binding protein involved in the export of acetylated sterols; secreted glycoprotein and member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); sterol export function is redundant with that of PRY2; may be involved in detoxification of hydrophobic compounds; PRY1 has a paralog, PRY2, that arose from the whole genome duplication [Source:SGD;Acc:S000003615])

HSP 1 Score: 53.5286 bits (127), Expect = 5.530e-9
Identity = 43/142 (30.28%), Postives = 64/142 (45.07%), Query Frame = 1 
Query:  124 LLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGN 549
            +L  HN  R       +H   PA     + W+D  A  AQ +AD   +D           Y   G+N+A  Y  +    V  W++E+  +DF        T  H+T +VW +T  VGCG+  C     G+ Y++C+Y P GN
Sbjct:  166 VLAEHNKKR------ALHKDTPA-----LSWSDTLASYAQDYAD--NYDCSGTLTHSGGPY---GENLALGY--DGPAAVDAWYNEISNYDFSNPGFSSNTG-HFTQVVWKSTTQVGCGIKTCGG-AWGD-YVICSYDPAGN 286
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Nematostella
Match: EDO31682 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX85])

HSP 1 Score: 72.4034 bits (176), Expect = 3.095e-16
Identity = 53/156 (33.97%), Postives = 70/156 (44.87%), Query Frame = 1 
Query:  109 EQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKC----QFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG----VQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNI 552
            E + Q L  HN+ R R G G            ++ W+ E A  AQKWA+      Q + DP  N         G+NI Y Y  N  E     V+ W+ EVK +DF   +    T  H++ LVW  T  +G G A     K GN +LV  Y P GN+
Sbjct:    2 ELQKQCLDAHNEFRTRHGAG------------KLAWSGELASEAQKWANHLASIDQMERDPLTN--------GGENIFYMYGGNPREACERAVRNWYQEVKNYDFKNPHSDPSTS-HFSQLVWKGTKKLGVGEAQS---KSGNFFLVARYHPKGNM 133
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Nematostella
Match: EDO37114 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGM4])

HSP 1 Score: 67.3958 bits (163), Expect = 3.031e-14
Identity = 52/154 (33.77%), Postives = 70/154 (45.45%), Query Frame = 1 
Query:  127 LKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQ----FDHDPAKNRKFNSYRWVGQNIAYWYSQN-----VTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQ 561
            L+ HN+ R R G             K+M W+   A  AQKWADK      F HD A     NS +  G+N+AY+  Q      + +    W+DE   +D+      K T  H+T LVW  T  +G G A   N K    Y+V  ++P GNI  Q
Sbjct:    6 LEAHNEYRKRHG------------AKEMTWSASLAADAQKWADKLSQTDAFKHDYA---SINS-KSQGENLAYFTPQKPNNTAIMDAFDAWYDESSKYDYANAKFSKETG-HFTQLVWKATQKMGIGTA--KNAKGDKEYVVARFSPAGNIKGQ 140
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Nematostella
Match: EDO35380 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLN4])

HSP 1 Score: 63.1586 bits (152), Expect = 1.352e-12
Identity = 45/149 (30.20%), Postives = 67/149 (44.97%), Query Frame = 1 
Query:  118 DQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDE-----VKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGN 549
            D  + +HN +R +      HG P      Q+ W+ E A RAQ WA+K           + +     G+NIAY  S    E V++W DE      KG+     +      LH+T +VW  T  +G G++       GN ++V  Y+P GN
Sbjct:   31 DSCVVVHNSVRQK------HGAP------QVTWDPELASRAQIWANK--LSSGAVLPWEIHESSSDGENIAYLSSPTCKEAVEYWMDEKYDYHAKGYCLSPPDLPDSYLLHFTQVVWKATRRIGVGIS-------GN-WIVVRYSPAGN 157
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Nematostella
Match: EDO50048 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF72])

HSP 1 Score: 62.003 bits (149), Expect = 4.048e-12
Identity = 53/169 (31.36%), Postives = 74/169 (43.79%), Query Frame = 1 
Query:  121 QLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKC----QFDHDPAKNRKFNSYRWVGQNIAYWYSQNVT-EGVQF----WFDEVKGFDFYTGNCKK--FTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTE 594
            + L  HN  R R      HG PP      M W+ + A  AQ WAD      +F+HD +  +        G+N+AY+   N   +G +     W+DE+  +DF  G  K      LH+T +VW  T  VG   A     K  N Y V  Y   GN G ++ +K  +P  E
Sbjct:    7 ECLDAHNMYRAR------HGVPP------MTWSRDLARDAQSWADTLARENKFEHDSSLKKLGE-----GENLAYFAPANRKCKGPEDTWCDWYDEIADYDFNKGAGKDRWSVVLHFTQVVWRGTTQVGVATAVSPVTK--NFYTVARYKIPGNQGTKEDFKKNVPPVE 156
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Nematostella
Match: EDO48881 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHM8])

HSP 1 Score: 60.4622 bits (145), Expect = 9.092e-12
Identity = 47/159 (29.56%), Postives = 71/159 (44.65%), Query Frame = 1 
Query:  109 EQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNR-KFNSYRWVGQNIAYWYSQNVT--EGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKV 576
            E K+ +LK HND R + G             K ++WN   A  AQ WA+         +N  + +S R  G++IAY     +T  +    W+ EV  + F        +  H+T +VWA +  +G G A  S+   G  ++V  Y P GN+  Q P  V
Sbjct:    1 EFKNDILKTHNDYRAQHG------------TKALKWNARLASEAQSWAENL-----AQRNAIQHSSSREYGESIAYMSGAVLTGRKATDMWYGEVDKYRFENPGFST-SSGHFTQVVWAGSTEMGAGKATSSS---GAHFVVARYTPPGNVMGQFPENV 138
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Medaka
Match: pi15a (peptidase inhibitor 15 [Source:NCBI gene;Acc:101173911])

HSP 1 Score: 109.383 bits (272), Expect = 1.221e-28
Identity = 73/211 (34.60%), Postives = 110/211 (52.13%), Query Frame = 1 
Query:   97 RLTTEQKDQL--LKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQ--NVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM-GNM-----YLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCN-GNELCH*IKEKSLKTKY 669
            R    Q D L  L  HN +R +V        PPA+NM+ M W++  A  A+ WA  C ++H P+   +F     +GQN++    +  ++ + V+ W+DEVK + F Y  +C            C HYT +VWA ++ VGC +  C N  + G++     YLVCNY+P GN   + PYKVG+PC+ CP  +  +  N +C      +LKT Y
Sbjct:   58 RRYISQNDMLAILDYHNKVRGKVF-------PPASNMEYMVWDETLAKTAEDWAHACLWEHGPSHLLRF-----LGQNLSVRTGRYRSILQLVKPWYDEVKDYSFPYPRDCNPRCPLRCYGPMCTHYTQMVWATSNKVGCAIHTCYNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSACPPSYGGSCSNNMCF----PALKTNY 252
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000020674.2 (cysteine-rich venom protein pseudecin-like [Source:NCBI gene;Acc:101157728])

HSP 1 Score: 108.612 bits (270), Expect = 1.310e-28
Identity = 62/167 (37.13%), Postives = 88/167 (52.69%), Query Frame = 1 
Query:  106 TEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG-VQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLV-CNYAPGGNIGYQKPYKVGMPCTECP 600
            T  + +++ +HN  R  V       +PPAA+M  M +++E A+ AQ W DKC  DH P  +R  N Y  +G+N+ Y  S  + +  +  W+ EV  F F   +       HYT +VW ++  VGCG+  CSN    N+YL  C+Y   GN     PYKVG PC  CP
Sbjct:   28 TAVQAEIVDVHNAFRRAV-------EPPAADMLMMSYSEELAVSAQAWVDKCVLDHGPPSSRMLNGYE-LGENLFYSTSPMLWKSIINAWYKEVSHFAFPNASTNGKPVGHYTQVVWNSSYKVGCGVTLCSN----NIYLYGCHYYRAGNFKRWPPYKVGTPCASCP 182
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000020676.2 (cysteine-rich venom protein pseudecin-like [Source:NCBI gene;Acc:101157728])

HSP 1 Score: 108.227 bits (269), Expect = 1.501e-28
Identity = 62/167 (37.13%), Postives = 88/167 (52.69%), Query Frame = 1 
Query:  106 TEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG-VQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLV-CNYAPGGNIGYQKPYKVGMPCTECP 600
            T  + +++ +HN  R  V       +PPAA+M  M +++E A+ AQ W DKC  DH P  +R  N Y  +G+N+ Y  S  + +  +  W+ EV  F F   +       HYT +VW ++  VGCG+  CSN    N+YL  C+Y   GN     PYKVG PC  CP
Sbjct:   13 TAVQAEIVDVHNAFRRAV-------EPPAADMLMMSYSEELAVSAQAWVDKCVLDHGPPSSRMLNGYE-LGENLFYSTSPMLWKSIINAWYKEVSHFAFPNASTNGKPVGHYTQVVWNSSYKVGCGVTLCSN----NIYLYGCHYYRAGNFKRWPPYKVGTPCASCP 167
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Medaka
Match: crispld1a (cysteine rich secretory protein LCCL domain containing 1 [Source:NCBI gene;Acc:101172850])

HSP 1 Score: 110.538 bits (275), Expect = 1.854e-27
Identity = 71/189 (37.57%), Postives = 98/189 (51.85%), Query Frame = 1 
Query:   97 RLTTEQKDQL-LKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNI-AYW-YSQNVTEGVQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            R  T+   QL L +HN +R     G V+  PPA+NM+ M W+ E    A++WA+ C ++H PA     +    +GQN+ A+W   Q  T  VQ W+DEVK + F Y   C  +         C HYT LVWA +  +GC +  C N  +        +YLVCNY+P GN     PYK G PC+ CP  +
Sbjct:   82 RAITDSDAQLILDLHNKLR-----GQVY--PPASNMEYMMWDTELERSAEEWAETCLWEHGPA-----SLLPQIGQNLGAHWGRYQPPTFHVQAWYDEVKDYSFPYPQECNPYCPFRCSGPVCTHYTQLVWATSSRIGCAINLCHNMDVWGQIWAKAVYLVCNYSPKGNWWGHAPYKHGTPCSACPPSY 258
[Close]
BLAST of SCP domain-containing protein vs. Ensembl Medaka
Match: crispld2 (cysteine rich secretory protein LCCL domain containing 2 [Source:NCBI gene;Acc:101174090])

HSP 1 Score: 110.153 bits (274), Expect = 1.886e-27
Identity = 63/182 (34.62%), Postives = 96/182 (52.75%), Query Frame = 1 
Query:  115 KDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEG--VQFWFDEVKGFDF-YTGNCKKF--------TCLHYTALVWANTDMVGCGLADCSNYKM------GNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERF 609
            ++++L +HN +R  V        P AANM+ M W+DE    A +WA++C+++H P      +    +GQN+A  + +  +    VQ W+DEVK + + Y   C  +         C HYT LVWA T+ VGC +  C    +        +YLVCNY+P GN   + PY+ G PC++CP  F
Sbjct:   76 REEILLLHNKLRSSV-------YPSAANMEHMVWDDELERSATQWAEECRWEHGPQ-----DLLMSIGQNLAVHWGRYRSPAFHVQAWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQLVWATTNRVGCAVHVCPKMNVWGEIWETAVYLVCNYSPKGNWIGEAPYRHGRPCSQCPPSF 245
[Close]
BLAST of SCP domain-containing protein vs. Planmine SMEST
Match: SMESG000019347.1 (SMESG000019347.1)

HSP 1 Score: 394.045 bits (1011), Expect = 2.696e-141
Identity = 195/195 (100.00%), Postives = 195/195 (100.00%), Query Frame = 1 
Query:   52 KPAAXXXXXXXXXXGRLTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELCH 636
            KPAAILSLFISSLLGRLTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELCH
Sbjct:    7 KPAAILSLFISSLLGRLTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELCH 201
[Close]
BLAST of SCP domain-containing protein vs. Planmine SMEST
Match: SMESG000062609.1 (SMESG000062609.1)

HSP 1 Score: 207.608 bits (527), Expect = 1.370e-67
Identity = 96/178 (53.93%), Postives = 123/178 (69.10%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELC 633
            +T  Q+ QL+  HN  R     G + GQP AANM +++WN+EAA RAQ  A+KC F HD  ++RKF +Y WVGQNIA+W S +VTEGV+ W+DEV G++F +  C  FTCLHYTALVWA T   GCG+ADCS   +G ++L CNY PGGN   +KPY+VG  C++CP    CN N LC
Sbjct:   22 VTPAQQKQLIDAHNKYRRDAAQGKIGGQPAAANMLELKWNNEAAQRAQNSANKCVFGHDQPRDRKFGNYDWVGQNIAFWSSDDVTEGVKMWYDEVNGYNFNSDQCSGFTCLHYTALVWAKTKEFGCGIADCSRQNLGKIFLFCNYGPGGNWNREKPYEVGKACSKCPSGTRCN-NGLC 198
[Close]
BLAST of SCP domain-containing protein vs. Planmine SMEST
Match: SMESG000062601.1 (SMESG000062601.1)

HSP 1 Score: 204.142 bits (518), Expect = 2.235e-66
Identity = 91/173 (52.60%), Postives = 120/173 (69.36%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCN 618
            +T +QK  L+  HN  R  V  G V  QP AANM +++W+ EA  +AQK+ +KC F HD +  RKF SY+WVGQNIAYW+S +VTEG++ W+DEVKG++F +  C   TCLHYT +VWA T   GCG+ADCS  K+G ++L CNYAPGGN   +K Y+VG  C++CP    CN
Sbjct:   19 VTPDQKKALIDAHNKYRREVAQGKVSKQPEAANMLELKWSSEAEAKAQKFVNKCVFKHDSSGERKFGSYQWVGQNIAYWHSDDVTEGIKMWYDEVKGYNFQSEKCSVSTCLHYTQVVWAKTKEFGCGVADCSKKKLGKIFLACNYAPGGNWNNEKAYEVGKACSKCPTGTKCN 191
[Close]
BLAST of SCP domain-containing protein vs. Planmine SMEST
Match: SMESG000062601.1 (SMESG000062601.1)

HSP 1 Score: 204.142 bits (518), Expect = 2.306e-66
Identity = 91/173 (52.60%), Postives = 120/173 (69.36%), Query Frame = 1 
Query:  100 LTTEQKDQLLKIHNDIRIRVGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCN 618
            +T +QK  L+  HN  R  V  G V  QP AANM +++W+ EA  +AQK+ +KC F HD +  RKF SY+WVGQNIAYW+S +VTEG++ W+DEVKG++F +  C   TCLHYT +VWA T   GCG+ADCS  K+G ++L CNYAPGGN   +K Y+VG  C++CP    CN
Sbjct:   21 VTPDQKKALIDAHNKYRREVAQGKVSKQPEAANMLELKWSSEAEAKAQKFVNKCVFKHDSSGERKFGSYQWVGQNIAYWHSDDVTEGIKMWYDEVKGYNFQSEKCSVSTCLHYTQVVWAKTKEFGCGVADCSKKKLGKIFLACNYAPGGNWNNEKAYEVGKACSKCPTGTKCN 193
[Close]
BLAST of SCP domain-containing protein vs. Planmine SMEST
Match: SMESG000047165.1 (SMESG000047165.1)

HSP 1 Score: 201.06 bits (510), Expect = 5.962e-65
Identity = 94/176 (53.41%), Postives = 119/176 (67.61%), Query Frame = 1 
Query:  118 DQLLKIHNDIRIR----VGHGMVHGQPPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAYWYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGLADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELC 633
            D+ +  H+  R R    V  G + GQP AANM +++WNDEAA RAQ  AD+C F HD +++R+F  Y WVGQNIAYW S +VT+G++ WFDEVK + F    C  FTCLHYTAL+WA T   GCG+ADCS   +GN+Y+VCNY PGGN   + PYKVG  C+ CP    C+ N LC
Sbjct:   30 DRCVFPHDQSRDRRFGDVAQGQISGQPAAANMLELKWNDEAAQRAQMSADRCVFQHDQSRDRRFGGYSWVGQNIAYWSSNDVTDGIKMWFDEVKDYTFNGDKCSGFTCLHYTALIWAKTKEFGCGIADCSRKGLGNIYIVCNYGPGGNWNNEAPYKVGQACSRCPNGTRCS-NGLC 204
The following BLAST results are available for this feature:
BLAST of SCP domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PI158.552e-2933.86peptidase inhibitor 15 [Source:HGNC Symbol;Acc:HGN... [more]
PI158.552e-2933.86peptidase inhibitor 15 [Source:HGNC Symbol;Acc:HGN... [more]
PI158.552e-2933.86peptidase inhibitor 15 [Source:HGNC Symbol;Acc:HGN... [more]
CRISP31.061e-2738.24cysteine rich secretory protein 3 [Source:HGNC Sym... [more]
CRISP31.646e-2738.24cysteine rich secretory protein 3 [Source:HGNC Sym... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
scl-52.591e-1928.27SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-101.834e-1728.11SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-121.682e-1626.80SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-96.016e-1626.15SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-141.060e-1526.56SCP-Like extracellular protein [Source:UniProtKB/... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG84831.452e-3541.18gene:FBgn0038126 transcript:FBtr0082782[more]
CG326791.015e-1529.73gene:FBgn0052679 transcript:FBtr0071469[more]
Ag5r3.297e-1431.69gene:FBgn0015010 transcript:FBtr0333658[more]
Ag5r3.297e-1431.69gene:FBgn0015010 transcript:FBtr0073937[more]
Ag5r3.297e-1431.69gene:FBgn0015010 transcript:FBtr0305582[more]
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BLAST of SCP domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
r3hdml1.031e-2833.87R3H domain containing-like [Source:ZFIN;Acc:ZDB-GE... [more]
r3hdml1.031e-2833.87R3H domain containing-like [Source:ZFIN;Acc:ZDB-GE... [more]
pi15a2.673e-2836.56peptidase inhibitor 15a [Source:NCBI gene;Acc:5619... [more]
pi15b7.085e-2734.64peptidase inhibitor 15b [Source:ZFIN;Acc:ZDB-GENE-... [more]
pi15b8.498e-2734.64peptidase inhibitor 15b [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pi152.835e-2832.66peptidase inhibitor 15 [Source:NCBI gene;Acc:10048... [more]
R3HDML1.031e-2731.55R3H domain containing-like [Source:NCBI gene;Acc:1... [more]
R3HDML1.289e-2731.55R3H domain containing-like [Source:NCBI gene;Acc:1... [more]
crispld22.687e-2736.79cysteine-rich secretory protein LCCL domain contai... [more]
crispld23.239e-2736.79cysteine-rich secretory protein LCCL domain contai... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Crispld21.570e-3033.18cysteine-rich secretory protein LCCL domain contai... [more]
Crispld21.570e-3033.18cysteine-rich secretory protein LCCL domain contai... [more]
Crispld21.199e-2935.03cysteine-rich secretory protein LCCL domain contai... [more]
Pi156.340e-2935.75peptidase inhibitor 15 [Source:MGI Symbol;Acc:MGI:... [more]
Pi163.071e-2834.59peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of SCP domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P0DPU1|VA576_SCODE8.062e-3541.28Scoloptoxin SSD976 OS=Scolopendra dehaani OX=26097... [more]
sp|P0DPV2|VA558_SCODE9.383e-3440.70Scoloptoxin SSD558 OS=Scolopendra dehaani OX=26097... [more]
sp|P0DPU2|VA543_SCODE9.084e-3237.14Scoloptoxin SSD43 OS=Scolopendra dehaani OX=260977... [more]
sp|P0DPU0|VA552_SCODE1.301e-3139.53Scoloptoxin SSD552 OS=Scolopendra dehaani OX=26097... [more]
sp|Q32LB5|GPRL1_BOVIN1.010e-2936.90GLIPR1-like protein 1 OS=Bos taurus OX=9913 GN=GLI... [more]
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BLAST of SCP domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HU243.928e-3941.90SCP domain-containing protein OS=Macrostomum ligna... [more]
C1LHZ33.546e-3740.74GLIPR1-like protein 1 OS=Schistosoma japonicum OX=... [more]
A0A564YFQ76.137e-3742.77SCP domain-containing protein OS=Hymenolepis dimin... [more]
A0A1I8HQH61.282e-3641.57SCP domain-containing protein OS=Macrostomum ligna... [more]
A0A094ZX171.376e-3640.37GLIPR1-like protein 1 (Fragment) OS=Schistosoma ha... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
r3hdml2.209e-3136.56R3H domain containing like [Source:NCBI gene;Acc:1... [more]
pi15a8.332e-3136.32peptidase inhibitor 15-A-like [Source:NCBI gene;Ac... [more]
pi15a1.308e-3036.32peptidase inhibitor 15-A-like [Source:NCBI gene;Ac... [more]
crispld1a2.001e-2634.04cysteine-rich secretory protein LCCL domain contai... [more]
crispld22.299e-2634.62cysteine-rich secretory protein LCCL domain contai... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000000374.16.309e-2630.09pep scaffold:Pmarinus_7.0:GL476650:75849:87118:-1 ... [more]
CRISP39.332e-2234.13cysteine rich secretory protein 3 [Source:HGNC Sym... [more]
ENSPMAT00000002250.19.127e-2133.52pep scaffold:Pmarinus_7.0:GL477299:1626:22672:-1 g... [more]
CLEC18A3.326e-925.77C-type lectin domain family 18 member A [Source:HG... [more]
CRISP21.333e-734.02cysteine rich secretory protein 2 [Source:HGNC Sym... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
PRY31.174e-1031.58Cell wall-associated protein involved in export of... [more]
PRY24.776e-930.17Sterol binding protein involved in the export of a... [more]
PRY15.530e-930.28Sterol binding protein involved in the export of a... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO316823.095e-1633.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371143.031e-1433.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO353801.352e-1230.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO500484.048e-1231.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO488819.092e-1229.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SCP domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pi15a1.221e-2834.60peptidase inhibitor 15 [Source:NCBI gene;Acc:10117... [more]
ENSORLT00000020674.21.310e-2837.13cysteine-rich venom protein pseudecin-like [Source... [more]
ENSORLT00000020676.21.501e-2837.13cysteine-rich venom protein pseudecin-like [Source... [more]
crispld1a1.854e-2737.57cysteine rich secretory protein LCCL domain contai... [more]
crispld21.886e-2734.62cysteine rich secretory protein LCCL domain contai... [more]
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BLAST of SCP domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019347.12.696e-141100.00SMESG000019347.1[more]
SMESG000062609.11.370e-6753.93SMESG000062609.1[more]
SMESG000062601.12.235e-6652.60SMESG000062601.1[more]
SMESG000062601.12.306e-6652.60SMESG000062601.1[more]
SMESG000047165.15.962e-6553.41SMESG000047165.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029130 ID=SMED30029130|Name=SCP domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=719bp
CTTTTGCAAATATTTATTTTATTACTTCATTAAATGATTCTTGAAATTTT
GAAGCCGGCAGCTATTTTGAGCCTTTTCATCAGTTCACTGTTGGGTAGAT
TGACGACTGAACAAAAGGATCAACTGTTGAAAATCCACAATGACATCCGC
ATTCGAGTGGGTCACGGAATGGTTCATGGTCAACCACCAGCTGCAAACAT
GAAGCAAATGCAGTGGAATGATGAGGCTGCTATCCGTGCGCAAAAATGGG
CGGATAAATGCCAATTCGATCATGATCCAGCGAAAAACCGAAAATTTAAT
AGCTACCGTTGGGTTGGCCAGAATATCGCTTATTGGTACAGTCAAAATGT
TACAGAAGGAGTCCAATTTTGGTTTGATGAAGTGAAAGGCTTTGATTTTT
ACACAGGAAACTGCAAGAAATTTACATGCTTACACTATACGGCGTTGGTA
TGGGCTAATACTGACATGGTGGGTTGTGGACTGGCAGACTGTTCTAACTA
TAAAATGGGAAACATGTATCTCGTGTGTAACTATGCACCAGGGGGAAATA
TTGGATATCAAAAACCATATAAAGTTGGAATGCCTTGCACCGAATGTCCA
GAGAGATTTCATTGCAATGGAAATGAATTGTGTCATTAAATTAAAGAAAA
ATCATTGAAAACTAAATATAATTTATTAGCTTTTCGAATATTAACACAGA
AACAAATAAGAAATACAAC
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protein sequence of SMED30029130-orf-1

>SMED30029130-orf-1 ID=SMED30029130-orf-1|Name=SMED30029130-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=202bp
MILEILKPAAILSLFISSLLGRLTTEQKDQLLKIHNDIRIRVGHGMVHGQ
PPAANMKQMQWNDEAAIRAQKWADKCQFDHDPAKNRKFNSYRWVGQNIAY
WYSQNVTEGVQFWFDEVKGFDFYTGNCKKFTCLHYTALVWANTDMVGCGL
ADCSNYKMGNMYLVCNYAPGGNIGYQKPYKVGMPCTECPERFHCNGNELC
H*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR035940CAP_sf
IPR001283CRISP-related
IPR002413V5_allergen-like
IPR014044CAP_domain
IPR018244Allrgn_V5/Tpx1_CS
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001283Cysteine-rich secretory protein-relatedPRINTSPR00837V5TPXLIKEcoord: 59..77
score: 36.73
coord: 162..175
score: 48.05
coord: 109..122
score: 31.2
coord: 132..148
score: 48.61
IPR001283Cysteine-rich secretory protein-relatedPANTHERPTHR10334CYSTEINE-RICH SECRETORY PROTEIN-RELATEDcoord: 22..198
IPR002413Venom allergen 5-likePRINTSPR00838V5ALLERGENcoord: 107..122
score: 36.72
coord: 131..150
score: 51.25
coord: 22..38
score: 39.34
IPR014044CAP domainSMARTSM00198SCP_3coord: 26..175
e-value: 1.2E-38
score: 144.4
IPR014044CAP domainPFAMPF00188CAPcoord: 33..167
e-value: 1.1E-21
score: 78.0
IPR035940CAP superfamilyGENE3DG3DSA:3.40.33.10coord: 16..201
e-value: 6.5E-56
score: 191.0
IPR035940CAP superfamilySUPERFAMILYSSF55797PR-1-likecoord: 15..182
NoneNo IPR availablePANTHERPTHR10334:SF344AT27079P-RELATEDcoord: 22..198
NoneNo IPR availableCDDcd05380CAP_eukcoord: 28..168
e-value: 1.37675E-42
score: 138.356
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.569
IPR018244Allergen V5/Tpx-1-related, conserved sitePROSITEPS01010CRISP_2coord: 162..173