Signal transducing adapter molecule 2

Overview
NameSignal transducing adapter molecule 2
Smed IDSMED30029121
Length (bp)1876
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Signal transducing adapter molecule 2 (SMED30029121) t-SNE clustered cells

Violin plots show distribution of expression levels for Signal transducing adapter molecule 2 (SMED30029121) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Signal transducing adapter molecule 2 (SMED30029121) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Signal transducing adapter molecule 2 (SMED30029121) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30029121

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cilated neuronSMED30029121SMESG000033040.1 dd_Smed_v4_2129_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029121SMESG000033040.1 Contig55609uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029121SMESG000033040.1 Contig55609newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30029121SMESG000033040.1 dd_Smed_v4_2129_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Human
Match: STAM2 (signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358])

HSP 1 Score: 253.832 bits (647), Expect = 3.469e-76
Identity = 188/556 (33.81%), Postives = 289/556 (51.98%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKN-IHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDDELNS--RNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS--MDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPMXXXXXXXXLHHPHH--AQFTSIPMQD-PSQ-----MMSRMMNENVNPAAPQSVLPGHHDPMLYQTMNYYGNMNAATAAQNTDIMYGSAGPGAAA----------AQLPFGPKQTIQQLPPG---SSYHPTMSNVTQKSNFPSTTHNNSSGLNAQDYHHRSL 1599
            +E ATNE  T +DW+ I+D+C+K    P   K+CLK I+KR+ +  PH+ L+++ LL ACV N G+ F  E+ SR F  E+++  KN  H K  E+L  +M +WS E     ++  I+   K +++       AG   +++  +N    N+     +E+ED+AKAI LSL+E +Q+    ++LYPS+     NK+            KVRALYDFEA EDNELTFK GEIII +D S+ +WW G NHRG G+FP+ FV+  +++E EA        A ++K +   +   +   + P    IDE K+D  L+V++  DPT + +PD  +L  LE  C+ MGP+ID++LE++DR ++ L ELN  V+E+ +LYN+L+ +       P   ++ +          LH P H     + +PMQ  P Q      M + +++ V  A   S+ P    P+     +   N+N++  AQ     Y S G    +           Q   G     QQ+      SSY  T SN+ Q + FP T   +       +YH + L
Sbjct:   13 VEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGITFPPAGSQTVSAAAKNGTSSNK----NKEDEDIAKAIELSLQEQKQQHTETKSLYPSSEIQLNNKVAR----------KVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTTNLNIETEA--------AAVDKLNVIDDDVEEIKKSEPEPVYIDEDKMDRALQVLQSIDPT-DSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLVNEA------PVYSVYSK----------LHPPAHYPPASSGVPMQTYPVQSHGGNYMGQSIHQ-VTVAQSYSLGPDQIGPL----RSLPPNVNSSVTAQPAQTSYLSTGQDTVSNPTYMNQNSNLQSATGTTAYTQQMGMSVDMSSYQNTTSNLPQLAGFPVTVPAHPVAQQHTNYHQQPL 524
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Human
Match: STAM (signal transducing adaptor molecule [Source:HGNC Symbol;Acc:HGNC:11357])

HSP 1 Score: 248.44 bits (633), Expect = 5.048e-74
Identity = 148/380 (38.95%), Postives = 221/380 (58.16%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ E     +   I+ + K L++   T+P I +   ++  +   +  K    V   +EEEDLAKAI LSLKE  Q+      LYPS  +   N         + +  KVRA+YDFEAAEDNELTFKAGEII  +D S+ +WW G  H+G G+FP+ FV+      AD   E    K EK +   +   Q ++    P    IDE K+D+ L++++  DP+ + +PD  EL  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNH--------QHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVT------ADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDD-QPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 377
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Human
Match: STAM (signal transducing adaptor molecule [Source:HGNC Symbol;Acc:HGNC:11357])

HSP 1 Score: 106.686 bits (265), Expect = 3.914e-26
Identity = 68/168 (40.48%), Postives = 95/168 (56.55%), Query Frame = 1 
Query:  319 MKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENE 795
            M +W+ E     +   I+ + K L++   T+P I +   ++  +   +  K    V   +EEEDLAKAI LSLKE  Q+      LYPS  +   N         + +  KVRA+YDFEAAEDNELTFKAGEII  +D S+ +WW G  H+G G+FP+ FV+ D+  E
Sbjct:    1 MVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNH--------QHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVTADLTAE 160
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Human
Match: GRAP2 (GRB2 related adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:4563])

HSP 1 Score: 62.003 bits (149), Expect = 1.084e-9
Identity = 33/77 (42.86%), Postives = 49/77 (63.64%), Query Frame = 1 
Query:  556 SNINHAI-NKMPTETVPLKK--QLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS 777
            S +N A+ ++  T+ V L+   ++   RALYDFEA ED+EL F +GE++  +D SN  WW G  H   G+FPA +V+
Sbjct:  250 SEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Human
Match: GRAP2 (GRB2 related adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:4563])

HSP 1 Score: 62.003 bits (149), Expect = 1.084e-9
Identity = 33/77 (42.86%), Postives = 49/77 (63.64%), Query Frame = 1 
Query:  556 SNINHAI-NKMPTETVPLKK--QLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS 777
            S +N A+ ++  T+ V L+   ++   RALYDFEA ED+EL F +GE++  +D SN  WW G  H   G+FPA +V+
Sbjct:  250 SEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Celegans
Match: stam-1 (Signal transducing adapter molecule 1 [Source:UniProtKB/Swiss-Prot;Acc:O01498])

HSP 1 Score: 172.94 bits (437), Expect = 8.219e-48
Identity = 129/387 (33.33%), Postives = 199/387 (51.42%), Query Frame = 1 
Query:   58 TEDDWTKILDVCE---KGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSE--YDCINELNKWL-QDTYPIIYAAGDDELNSRNPIKGN-----RKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPK--VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPM 1179
            T ++W  IL  C+      +  K  +K + KRL N +PH+VL +I +LD+C  N  E F KE+SS  F+NE+K+   +  ++  E++   ++KW      +E     I  L+K L  D Y  +    DD  +    I          V   QEEE +AKAIA SL ++E++ +    ++  +   K  +  V     +P+  VRALYDFEAAE NEL+F AG+II   D SN HWW G     QG+FP+ FV+  +++   K  +S++   E                 +   I+E+ +  CL+V+ + DPTGE R DP +L++LEA     G LID  L  +DR  N L +++  + +   LY++ + +GG      G  M+ QPM
Sbjct:   17 TVENWEGILAFCDMINNDFEGSKTGIKSLRKRLNNRDPHVVLLAISVLDSCWANCEERFRKEVSSAQFINELKALCTSSQRQVAEKMRLTVQKWVDTECKTEQSLSLIVTLHKNLVADGYSFVV---DDPKSKTKAIDAKFANDPNYVGSAQEEEAIAKAIAASLADAEKQEKAKKSTSTMYPSAKASSPAVQTNSNIPEKNVRALYDFEAAESNELSFVAGDIITITDESNPHWWTGRIGTQQGLFPSSFVTNQLDDLKSKETDSSQKAPE-----------------VVASINEAILVRCLQVLHECDPTGE-RQDPEDLAQLEAASYAQGNLIDAHLASIDRQSNSLAQIDVAIRDVLALYDDAIQKGGFQHQSQG--MYQQPM 380
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Celegans
Match: stam-1 (Signal transducing adapter molecule 1 [Source:UniProtKB/Swiss-Prot;Acc:O01498])

HSP 1 Score: 174.096 bits (440), Expect = 1.213e-47
Identity = 129/387 (33.33%), Postives = 199/387 (51.42%), Query Frame = 1 
Query:   58 TEDDWTKILDVCE---KGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSE--YDCINELNKWL-QDTYPIIYAAGDDELNSRNPIKGN-----RKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPK--VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPM 1179
            T ++W  IL  C+      +  K  +K + KRL N +PH+VL +I +LD+C  N  E F KE+SS  F+NE+K+   +  ++  E++   ++KW      +E     I  L+K L  D Y  +    DD  +    I          V   QEEE +AKAIA SL ++E++ +    ++  +   K  +  V     +P+  VRALYDFEAAE NEL+F AG+II   D SN HWW G     QG+FP+ FV+  +++   K  +S++   E                 +   I+E+ +  CL+V+ + DPTGE R DP +L++LEA     G LID  L  +DR  N L +++  + +   LY++ + +GG      G  M+ QPM
Sbjct:   25 TVENWEGILAFCDMINNDFEGSKTGIKSLRKRLNNRDPHVVLLAISVLDSCWANCEERFRKEVSSAQFINELKALCTSSQRQVAEKMRLTVQKWVDTECKTEQSLSLIVTLHKNLVADGYSFVV---DDPKSKTKAIDAKFANDPNYVGSAQEEEAIAKAIAASLADAEKQEKAKKSTSTMYPSAKASSPAVQTNSNIPEKNVRALYDFEAAESNELSFVAGDIITITDESNPHWWTGRIGTQQGLFPSSFVTNQLDDLKSKETDSSQKAPE-----------------VVASINEAILVRCLQVLHECDPTGE-RQDPEDLAQLEAASYAQGNLIDAHLASIDRQSNSLAQIDVAIRDVLALYDDAIQKGGFQHQSQG--MYQQPM 388
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Celegans
Match: stam-1 (Signal transducing adapter molecule 1 [Source:UniProtKB/Swiss-Prot;Acc:O01498])

HSP 1 Score: 174.096 bits (440), Expect = 1.213e-47
Identity = 129/387 (33.33%), Postives = 199/387 (51.42%), Query Frame = 1 
Query:   58 TEDDWTKILDVCE---KGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSE--YDCINELNKWL-QDTYPIIYAAGDDELNSRNPIKGN-----RKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPK--VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPM 1179
            T ++W  IL  C+      +  K  +K + KRL N +PH+VL +I +LD+C  N  E F KE+SS  F+NE+K+   +  ++  E++   ++KW      +E     I  L+K L  D Y  +    DD  +    I          V   QEEE +AKAIA SL ++E++ +    ++  +   K  +  V     +P+  VRALYDFEAAE NEL+F AG+II   D SN HWW G     QG+FP+ FV+  +++   K  +S++   E                 +   I+E+ +  CL+V+ + DPTGE R DP +L++LEA     G LID  L  +DR  N L +++  + +   LY++ + +GG      G  M+ QPM
Sbjct:   25 TVENWEGILAFCDMINNDFEGSKTGIKSLRKRLNNRDPHVVLLAISVLDSCWANCEERFRKEVSSAQFINELKALCTSSQRQVAEKMRLTVQKWVDTECKTEQSLSLIVTLHKNLVADGYSFVV---DDPKSKTKAIDAKFANDPNYVGSAQEEEAIAKAIAASLADAEKQEKAKKSTSTMYPSAKASSPAVQTNSNIPEKNVRALYDFEAAESNELSFVAGDIITITDESNPHWWTGRIGTQQGLFPSSFVTNQLDDLKSKETDSSQKAPE-----------------VVASINEAILVRCLQVLHECDPTGE-RQDPEDLAQLEAASYAQGNLIDAHLASIDRQSNSLAQIDVAIRDVLALYDDAIQKGGFQHQSQG--MYQQPM 388
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Celegans
Match: hgrs-1 (Hepatocyte Growth factor-Regulated TK Substrate (HRS) family [Source:UniProtKB/TrEMBL;Acc:Q17796])

HSP 1 Score: 57.7658 bits (138), Expect = 1.869e-8
Identity = 41/142 (28.87%), Postives = 72/142 (50.70%), Query Frame = 1 
Query:   28 LIEIATNEKQTEDDWTKIL---DVCEKGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIK-----SKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDD 426
            +++ AT+    E +W  I+   D+   G    K  L+ I KR+ + NPH+V  ++++LDACV+N G     E+++R F+ + K     +K   +  K+LE    M++ W+       EY       K + DT+ ++  AG D
Sbjct:    8 VLDQATDSTLVEPNWEGIILCTDMIRSGEVPAKPSLQAIRKRMQHENPHVVNHTLLVLDACVKNCGHKVHAEVATREFMEDFKNLVTENKYDEVKNKSLE----MLQCWATAFANKPEY-------KMVVDTHNLMKLAGFD 138
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Celegans
Match: hgrs-1 (Hepatocyte Growth factor-Regulated TK Substrate (HRS) family [Source:UniProtKB/TrEMBL;Acc:Q17796])

HSP 1 Score: 57.7658 bits (138), Expect = 1.869e-8
Identity = 41/142 (28.87%), Postives = 72/142 (50.70%), Query Frame = 1 
Query:   28 LIEIATNEKQTEDDWTKIL---DVCEKGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIK-----SKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDD 426
            +++ AT+    E +W  I+   D+   G    K  L+ I KR+ + NPH+V  ++++LDACV+N G     E+++R F+ + K     +K   +  K+LE    M++ W+       EY       K + DT+ ++  AG D
Sbjct:    8 VLDQATDSTLVEPNWEGIILCTDMIRSGEVPAKPSLQAIRKRMQHENPHVVNHTLLVLDACVKNCGHKVHAEVATREFMEDFKNLVTENKYDEVKNKSLE----MLQCWATAFANKPEY-------KMVVDTHNLMKLAGFD 138
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Fly
Match: Stam (gene:FBgn0027363 transcript:FBtr0080143)

HSP 1 Score: 210.69 bits (535), Expect = 4.489e-59
Identity = 141/408 (34.56%), Postives = 216/408 (52.94%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSEYDCINELNKWLQDTYPIIYAA----GDDELNSRNPI------------KGNRKVVQGQEEEDLAKAIALSLKESEQKRQ--------------NLYPSNINHAINKMPTETVPLKKQLP-KVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKF---------GESNRAKIEKGSAAINHQPDSYSTRPITPV-IDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELM 1122
            +E AT+E  T D+W+ ILDVC+K T NP   K+CLK +++R+ + +PH+V+++I LLDA   N G+P   E++SR F  E +        K   ++  ++K W+     ++Y    EL     D  P +YA     G D  N  +              K    V   QEE+D+AKAI LSLKE++   +              +LYPS      +    E        P KVRALYDFEAAE+NELTF AGEII  +D S+ +WW G N RG+G+FP+ FV+ D+  + ++            + + +++  +A       + +     PV IDESK+D  L ++ +A+P    + D  E+ +LE +   MGPLID ELE+VDR +  L +L+ +++++  LY+ LM
Sbjct:   14 VEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRMGHTDPHVVMQAITLLDALSNNCGKPLHLEVASRDFETEFRRLLAKAQPKVSLKMRQVLKNWAE----NDYKNDREL-----DLIPALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTEAAAAAAAAQPVEIDESKIDRLLHLLHEANPEDPSQ-DSDEMLQLEQEVHQMGPLIDAELERVDRKHAQLTQLSSDLVDAINLYHTLM 411
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Fly
Match: Abp1 (gene:FBgn0036372 transcript:FBtr0075819)

HSP 1 Score: 58.151 bits (139), Expect = 1.756e-8
Identity = 23/54 (42.59%), Postives = 36/54 (66.67%), Query Frame = 1 
Query:  622 KVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQ-GMFPAQFVSM 780
            + RALYD++AA++ E+TF  G++I  +D  +E WW G    G  G+FPA +V +
Sbjct:  476 RARALYDYQAADETEITFDPGDVITHIDQIDEGWWQGLGPDGTYGLFPANYVEI 529
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087695)

HSP 1 Score: 55.0694 bits (131), Expect = 2.828e-8
Identity = 26/66 (39.39%), Postives = 41/66 (62.12%), Query Frame = 1 
Query:  589 TETVPLKKQLPK---VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS 777
            ++ V L+  +P+   V+ALYDF   E  EL F+ G++I   D S+E+WW G     +G+FPA +V+
Sbjct:  142 SQDVKLRDMIPEEMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVT 207
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087694)

HSP 1 Score: 55.0694 bits (131), Expect = 2.828e-8
Identity = 26/66 (39.39%), Postives = 41/66 (62.12%), Query Frame = 1 
Query:  589 TETVPLKKQLPK---VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS 777
            ++ V L+  +P+   V+ALYDF   E  EL F+ G++I   D S+E+WW G     +G+FPA +V+
Sbjct:  142 SQDVKLRDMIPEEMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVT 207
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Fly
Match: drk (gene:FBgn0004638 transcript:FBtr0087698)

HSP 1 Score: 55.0694 bits (131), Expect = 2.828e-8
Identity = 26/66 (39.39%), Postives = 41/66 (62.12%), Query Frame = 1 
Query:  589 TETVPLKKQLPK---VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS 777
            ++ V L+  +P+   V+ALYDF   E  EL F+ G++I   D S+E+WW G     +G+FPA +V+
Sbjct:  142 SQDVKLRDMIPEEMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVT 207
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Zebrafish
Match: stam (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:ZFIN;Acc:ZDB-GENE-031118-123])

HSP 1 Score: 242.662 bits (618), Expect = 2.559e-72
Identity = 146/381 (38.32%), Postives = 219/381 (57.48%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDDE---------LNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PKECL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ +     +   I+ + K L++   I  A G            L +++P     K    +EEEDLAKAI LSLK+   ++  +  S +  + + + T     K    KVRA+YDFEAAEDNELTFK+GEII  +D S+ +WW G  ++G G+FP+ FV+      AD   E    K EK +   +   Q ++    P    IDE K+D+ L++I+ ADPT + + D  EL +LEA C  MGPLIDQ+LE  DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSEMNTAEDWGLILDICDKIGQSRTGPKECLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSREFASEVSNVLNKGHPKVCEKLKALMVEWAEDFRNDPQLSLISAMIKNLREQGVIFPAVGSQAAEQAKASPALVAKDPATSTNK----KEEEDLAKAIELSLKDQRHQQPQVSLSGLYPSTSSLLTSH---KTDGRKVRAIYDFEAAEDNELTFKSGEIITILDDSDPNWWKGETYQGVGLFPSNFVT------ADLTAEPEMMKTEKKTVQFSEEVQVETIEPEPEPAYIDEEKMDQLLQMIQSADPTDD-QSDTCELLQLEAACNQMGPLIDQKLEDTDRKHSELSELNVKVMEALSLYAKLMNE 379
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Zebrafish
Match: stam2 (signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [Source:ZFIN;Acc:ZDB-GENE-041114-64])

HSP 1 Score: 222.631 bits (566), Expect = 7.103e-65
Identity = 138/388 (35.57%), Postives = 213/388 (54.90%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSREL-TGSEYDCINELNKWLQD---TYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLK------------KQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKI-EKGSAAINHQPDSYSTRPITPV-IDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E AT+E  T +DW  I+D+C++    P   K+CL+ I+KR+ +  PH+ ++++ LL ACV N G+ F  E+ SR F +E++      H K  E+L  +M +W+ +     +   I    K L++   T+P       +  +S           +   ++DLAKAI LSL+E +Q+                 TET PL             K+  KVRALYDFEAAEDNELTFKAGE++I +D S+ +WW G NHRG G+FP+ FV+ ++  E D      +  + E+    +  +P+        PV IDE K+D+ L ++++ DP  +  PD  EL  LE  C  M PLID++L+++DR ++ L ELN  V+E+ +LYN+LM + 
Sbjct:   13 VEKATSETNTVEDWGLIMDICDRVGTAPNGAKDCLRSIMKRVNHKVPHVAMQALTLLGACVANSGKIFHLEICSREFASEVRGVLNRAHPKVNEKLKALMAEWAEDFQKDPQLSLIGATIKSLKEEGVTFPTA-----NPQSSSTKPSSTPATSRASADDDLAKAIELSLQEQKQQ-----------------TETRPLTVIADPPYNTNGGKESRKVRALYDFEAAEDNELTFKAGELVIILDDSDPNWWKGENHRGVGLFPSNFVTTNLNAEPDPVMYVEKTVVPEEPIVEVKAEPE--------PVYIDEEKMDKTLYLLQNTDP-ADATPDGPELLTLEDACEKMNPLIDEKLQEIDRKHSELSELNVKVLEALELYNQLMNEA 369
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Zebrafish
Match: si:dkey-40c11.2 (si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-300])

HSP 1 Score: 64.6994 bits (156), Expect = 9.685e-12
Identity = 28/56 (50.00%), Postives = 42/56 (75.00%), Query Frame = 1 
Query:  610 KQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRG-QGMFPAQFV 774
            ++L +VRALYD++A +D EL+F+ G+II DV+  ++ WW G +  G QG+FPA FV
Sbjct:  113 ERLLRVRALYDYQAEDDTELSFEPGDIISDVETIDKAWWRGCSKDGRQGLFPANFV 168
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Zebrafish
Match: si:dkey-40c11.2 (si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-300])

HSP 1 Score: 66.6254 bits (161), Expect = 6.027e-11
Identity = 41/121 (33.88%), Postives = 63/121 (52.07%), Query Frame = 1 
Query:  415 AGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRG-QGMFPAQFV 774
             G+DE     P+ G  + V   E     +      +E E +        I   + K   E+ P  ++L +VRALYD++A +D EL+F+ G+II DV+  ++ WW G +  G QG+FPA FV
Sbjct:  658 TGEDEFECGTPLNGTVEDVDVSEHSTPERYCYTVNREEEDE--------IQTEVLKENGESSP--ERLLRVRALYDYQAEDDTELSFEPGDIISDVETIDKAWWRGCSKDGRQGLFPANFV 768
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Zebrafish
Match: si:dkey-40c11.2 (si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-300])

HSP 1 Score: 66.2402 bits (160), Expect = 7.801e-11
Identity = 41/121 (33.88%), Postives = 63/121 (52.07%), Query Frame = 1 
Query:  415 AGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRG-QGMFPAQFV 774
             G+DE     P+ G  + V   E     +      +E E +        I   + K   E+ P  ++L +VRALYD++A +D EL+F+ G+II DV+  ++ WW G +  G QG+FPA FV
Sbjct:  632 TGEDEFECGTPLNGTVEDVDVSEHSTPERYCYTVNREEEDE--------IQTEVLKENGESSP--ERLLRVRALYDYQAEDDTELSFEPGDIISDVETIDKAWWRGCSKDGRQGLFPANFV 742
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Xenopus
Match: adamts8 (ADAM metallopeptidase with thrombospondin type 1 motif 8 [Source:Xenbase;Acc:XB-GENE-994782])

HSP 1 Score: 247.284 bits (630), Expect = 9.521e-74
Identity = 149/383 (38.90%), Postives = 225/383 (58.75%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDE------LNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKR--QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ S     H K  E+L  +M +W+ E     +   I+ + K L++   T+P + +   D+      L +++P     K    +EEEDLAKAI LSLKE +Q+     LYPS+         +    LK +  KV+A+YDFEAAEDNELTFKAG+I+  +D S+ +WW G  + G G+FP+ FV+ D+  E +        K EK +   +   Q ++    P    IDE K+D  L++++ ADPT  L PDP +L  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSELNTAEDWGLILDLCDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSSVLNKGHPKVCEKLKALMVEWADEFKNDPQLSLISAMIKNLKEQGVTFPAVGSQAADQAKASPALVAKDPGTAATK----KEEEDLAKAIELSLKEQKQQSTVSGLYPSS---------SLLSALKPEGRKVQAIYDFEAAEDNELTFKAGDIVTVLDDSDPNWWKGETNEGIGLFPSNFVTADLTAELEMI------KTEKKTVQFSDEVQVETIEPEPEPVYIDEDKMDHLLQMLQSADPTDGL-PDPTDLLHLEAACHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 375
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Xenopus
Match: adamts8 (ADAM metallopeptidase with thrombospondin type 1 motif 8 [Source:Xenbase;Acc:XB-GENE-994782])

HSP 1 Score: 247.284 bits (630), Expect = 1.162e-73
Identity = 147/379 (38.79%), Postives = 222/379 (58.58%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR--QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ S     H K  E+L  +M +W+ E     +   I+ + K L++   T+P + +   D+  +   +  K        +EEEDLAKAI LSLKE +Q+     LYPS+         +    LK +  KV+A+YDFEAAEDNELTFKAG+I+  +D S+ +WW G  + G G+FP+ FV+ D+  E +        K EK +   +   Q ++    P    IDE K+D  L++++ ADPT  L PDP +L  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSELNTAEDWGLILDLCDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSSVLNKGHPKVCEKLKALMVEWADEFKNDPQLSLISAMIKNLKEQGVTFPAVGSQAADQAKASPALVAKDPGTAATKKEEEDLAKAIELSLKEQKQQSTVSGLYPSS---------SLLSALKPEGRKVQAIYDFEAAEDNELTFKAGDIVTVLDDSDPNWWKGETNEGIGLFPSNFVTADLTAELEMI------KTEKKTVQFSDEVQVETIEPEPEPVYIDEDKMDHLLQMLQSADPTDGL-PDPTDLLHLEAACHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 375
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Xenopus
Match: adamts8 (ADAM metallopeptidase with thrombospondin type 1 motif 8 [Source:Xenbase;Acc:XB-GENE-994782])

HSP 1 Score: 244.588 bits (623), Expect = 2.041e-73
Identity = 149/383 (38.90%), Postives = 225/383 (58.75%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDE------LNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKR--QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ S     H K  E+L  +M +W+ E     +   I+ + K L++   T+P + +   D+      L +++P     K    +EEEDLAKAI LSLKE +Q+     LYPS+         +    LK +  KV+A+YDFEAAEDNELTFKAG+I+  +D S+ +WW G  + G G+FP+ FV+ D+  E +        K EK +   +   Q ++    P    IDE K+D  L++++ ADPT  L PDP +L  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSELNTAEDWGLILDLCDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSSVLNKGHPKVCEKLKALMVEWADEFKNDPQLSLISAMIKNLKEQGVTFPAVGSQAADQAKASPALVAKDPGTAATK----KEEEDLAKAIELSLKEQKQQSTVSGLYPSS---------SLLSALKPEGRKVQAIYDFEAAEDNELTFKAGDIVTVLDDSDPNWWKGETNEGIGLFPSNFVTADLTAELEMI------KTEKKTVQFSDEVQVETIEPEPEPVYIDEDKMDHLLQMLQSADPTDGL-PDPTDLLHLEAACHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 375
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Xenopus
Match: adamts8 (ADAM metallopeptidase with thrombospondin type 1 motif 8 [Source:Xenbase;Acc:XB-GENE-994782])

HSP 1 Score: 245.743 bits (626), Expect = 3.081e-73
Identity = 148/380 (38.95%), Postives = 223/380 (58.68%), Query Frame = 1 
Query:   40 ATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDE------LNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKR--QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ S     H K  E+L  +M +W+ E     +   I+ + K L++   T+P + +   D+      L +++P     K    +EEEDLAKAI LSLKE +Q+     LYPS+         +    LK +  KV+A+YDFEAAEDNELTFKAG+I+  +D S+ +WW G  + G G+FP+ FV+ D+  E +        K EK +   +   Q ++    P    IDE K+D  L++++ ADPT  L PDP +L  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   16 ATSELNTAEDWGLILDLCDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSSVLNKGHPKVCEKLKALMVEWADEFKNDPQLSLISAMIKNLKEQGVTFPAVGSQAADQAKASPALVAKDPGTAATK----KEEEDLAKAIELSLKEQKQQSTVSGLYPSS---------SLLSALKPEGRKVQAIYDFEAAEDNELTFKAGDIVTVLDDSDPNWWKGETNEGIGLFPSNFVTADLTAELEMI------KTEKKTVQFSDEVQVETIEPEPEPVYIDEDKMDHLLQMLQSADPTDGL-PDPTDLLHLEAACHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 375
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Xenopus
Match: adamts8 (ADAM metallopeptidase with thrombospondin type 1 motif 8 [Source:Xenbase;Acc:XB-GENE-994782])

HSP 1 Score: 243.432 bits (620), Expect = 1.108e-72
Identity = 148/380 (38.95%), Postives = 223/380 (58.68%), Query Frame = 1 
Query:   40 ATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDE------LNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKR--QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ S     H K  E+L  +M +W+ E     +   I+ + K L++   T+P + +   D+      L +++P     K    +EEEDLAKAI LSLKE +Q+     LYPS+         +    LK +  KV+A+YDFEAAEDNELTFKAG+I+  +D S+ +WW G  + G G+FP+ FV+ D+  E +        K EK +   +   Q ++    P    IDE K+D  L++++ ADPT  L PDP +L  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   16 ATSELNTAEDWGLILDLCDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSSVLNKGHPKVCEKLKALMVEWADEFKNDPQLSLISAMIKNLKEQGVTFPAVGSQAADQAKASPALVAKDPGTAATK----KEEEDLAKAIELSLKEQKQQSTVSGLYPSS---------SLLSALKPEGRKVQAIYDFEAAEDNELTFKAGDIVTVLDDSDPNWWKGETNEGIGLFPSNFVTADLTAELEMI------KTEKKTVQFSDEVQVETIEPEPEPVYIDEDKMDHLLQMLQSADPTDGL-PDPTDLLHLEAACHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 375
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Mouse
Match: Stam (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:MGI Symbol;Acc:MGI:1329014])

HSP 1 Score: 249.21 bits (635), Expect = 2.164e-75
Identity = 150/380 (39.47%), Postives = 220/380 (57.89%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ E     +   I+ + K L++   T+P I +   ++  +   +  K    V   +EEEDLAKAI LSLKE  Q+      LYPS  N   N         + +  KVRA+YDFEAAEDNELTFKAGEII  +D S+ +WW G  H+G G+FP+ FV+      AD   E    K EK +   N   Q ++    P    IDE K+D+ L++++  DP+   +PD  EL  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQSAPVSTLYPSTSNLLTNH--------QHEGRKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFVT------ADLTAEPEMIKTEKKTVQFNDDVQIETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDN-QPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 377
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Mouse
Match: Stam (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:MGI Symbol;Acc:MGI:1329014])

HSP 1 Score: 251.136 bits (640), Expect = 4.354e-75
Identity = 149/380 (39.21%), Postives = 221/380 (58.16%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ E     +   I+ + K L++   T+P I +   ++  +   +  K    V   +EEEDLAKAI LSLKE  Q+      LYPS  N   N         + +  KVRA+YDFEAAEDNELTFKAGEII  +D S+ +WW G  H+G G+FP+ FV+ D+  E +        K EK +   N   Q ++    P    IDE K+D+ L++++  DP+   +PD  EL  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQSAPVSTLYPSTSNLLTNH--------QHEGRKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFVTADLTAEPEMI------KTEKKTVQFNDDVQIETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDN-QPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 377
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Mouse
Match: Stam2 (signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [Source:MGI Symbol;Acc:MGI:1929100])

HSP 1 Score: 246.899 bits (629), Expect = 9.599e-74
Identity = 142/375 (37.87%), Postives = 219/375 (58.40%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKN-IHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQK---RQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E ATNE  T +DW+ I+D+C++    P   K+CLK I+KR+ +  PH+ L+++ LL ACV N G+ F  E+ SR F  E++S  KN  H K  E+L  +M +WS E     ++  I+   K +++      +AG   + +    K    + + +E+ED+AKAI LSL+E +Q+    + LYP          P E+    K   +VRALYDFEA EDNELTFK GE+I  +D S+ +WW G NHRG G+FP+ FV+ D+  E +       A ++K +   +   +   + P    IDE K+D  L++++  DP  E +PD  +L  LE  C+ MGP+ID++LE++DR ++ L ELN  V+E+  LYN+L+ + 
Sbjct:   13 VEKATNEYNTTEDWSLIMDICDRVGSTPSGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRSVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAA--AKNGTSLNKNKEDEDIAKAIELSLQEQKQQYTETKALYP----------PAESQLNNKAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVE------TATVDKLNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPK-ESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVNEA 368
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Mouse
Match: Stam2 (signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [Source:MGI Symbol;Acc:MGI:1929100])

HSP 1 Score: 203.756 bits (517), Expect = 1.009e-58
Identity = 126/374 (33.69%), Postives = 199/374 (53.21%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQK---RQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E ATNE  T +DW+ I+D+C++    P   K+CLK I+KR+ +  PH+ L+++                                  H K  E+L  +M +WS E     ++  I+   K +++      +AG   + +    K    + + +E+ED+AKAI LSL+E +Q+    + LYP          P E+    K   +VRALYDFEA EDNELTFK GE+I  +D S+ +WW G NHRG G+FP+ FV+ D+  E +       A ++K +   +   +   + P    IDE K+D  L++++  DP  E +PD  +L  LE  C+ MGP+ID++LE++DR ++ L ELN  V+E+  LYN+L+ + 
Sbjct:   13 VEKATNEYNTTEDWSLIMDICDRVGSTPSGAKDCLKAIMKRVNHKVPHVALQAL--------------------------------TAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAA--AKNGTSLNKNKEDEDIAKAIELSLQEQKQQYTETKALYP----------PAESQLNNKAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVE------TATVDKLNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPK-ESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVNEA 335
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Mouse
Match: Stam (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:MGI Symbol;Acc:MGI:1329014])

HSP 1 Score: 110.923 bits (276), Expect = 2.608e-27
Identity = 70/195 (35.90%), Postives = 110/195 (56.41%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAIN 579
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ E     +   I+ + K L++   T+P I +   ++  +   +  K    V   +EEEDLAKAI LSLKE  Q+      LYPS  N   N
Sbjct:   10 LEKATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQSAPVSTLYPSTSNLLTN 204
[Close]
BLAST of Signal transducing adapter molecule 2 vs. UniProt/SwissProt
Match: sp|O75886|STAM2_HUMAN (Signal transducing adapter molecule 2 OS=Homo sapiens OX=9606 GN=STAM2 PE=1 SV=1)

HSP 1 Score: 253.832 bits (647), Expect = 1.666e-75
Identity = 188/556 (33.81%), Postives = 289/556 (51.98%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKN-IHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDDELNS--RNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS--MDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPMXXXXXXXXLHHPHH--AQFTSIPMQD-PSQ-----MMSRMMNENVNPAAPQSVLPGHHDPMLYQTMNYYGNMNAATAAQNTDIMYGSAGPGAAA----------AQLPFGPKQTIQQLPPG---SSYHPTMSNVTQKSNFPSTTHNNSSGLNAQDYHHRSL 1599
            +E ATNE  T +DW+ I+D+C+K    P   K+CLK I+KR+ +  PH+ L+++ LL ACV N G+ F  E+ SR F  E+++  KN  H K  E+L  +M +WS E     ++  I+   K +++       AG   +++  +N    N+     +E+ED+AKAI LSL+E +Q+    ++LYPS+     NK+            KVRALYDFEA EDNELTFK GEIII +D S+ +WW G NHRG G+FP+ FV+  +++E EA        A ++K +   +   +   + P    IDE K+D  L+V++  DPT + +PD  +L  LE  C+ MGP+ID++LE++DR ++ L ELN  V+E+ +LYN+L+ +       P   ++ +          LH P H     + +PMQ  P Q      M + +++ V  A   S+ P    P+     +   N+N++  AQ     Y S G    +           Q   G     QQ+      SSY  T SN+ Q + FP T   +       +YH + L
Sbjct:   13 VEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGITFPPAGSQTVSAAAKNGTSSNK----NKEDEDIAKAIELSLQEQKQQHTETKSLYPSSEIQLNNKVAR----------KVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTTNLNIETEA--------AAVDKLNVIDDDVEEIKKSEPEPVYIDEDKMDRALQVLQSIDPT-DSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLVNEA------PVYSVYSK----------LHPPAHYPPASSGVPMQTYPVQSHGGNYMGQSIHQ-VTVAQSYSLGPDQIGPL----RSLPPNVNSSVTAQPAQTSYLSTGQDTVSNPTYMNQNSNLQSATGTTAYTQQMGMSVDMSSYQNTTSNLPQLAGFPVTVPAHPVAQQHTNYHQQPL 524
[Close]
BLAST of Signal transducing adapter molecule 2 vs. UniProt/SwissProt
Match: sp|P70297|STAM1_MOUSE (Signal transducing adapter molecule 1 OS=Mus musculus OX=10090 GN=Stam PE=1 SV=3)

HSP 1 Score: 251.136 bits (640), Expect = 3.045e-74
Identity = 149/380 (39.21%), Postives = 221/380 (58.16%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ E     +   I+ + K L++   T+P I +   ++  +   +  K    V   +EEEDLAKAI LSLKE  Q+      LYPS  N   N         + +  KVRA+YDFEAAEDNELTFKAGEII  +D S+ +WW G  H+G G+FP+ FV+ D+  E +        K EK +   N   Q ++    P    IDE K+D+ L++++  DP+   +PD  EL  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQSAPVSTLYPSTSNLLTNH--------QHEGRKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFVTADLTAEPEMI------KTEKKTVQFNDDVQIETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDN-QPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 377
[Close]
BLAST of Signal transducing adapter molecule 2 vs. UniProt/SwissProt
Match: sp|Q92783|STAM1_HUMAN (Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3)

HSP 1 Score: 248.44 bits (633), Expect = 2.424e-73
Identity = 148/380 (38.95%), Postives = 221/380 (58.16%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPI--KGNRKVVQGQEEEDLAKAIALSLKESEQKR---QNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINH--QPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PK+CL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ E     +   I+ + K L++   T+P I +   ++  +   +  K    V   +EEEDLAKAI LSLKE  Q+      LYPS  +   N         + +  KVRA+YDFEAAEDNELTFKAGEII  +D S+ +WW G  H+G G+FP+ FV+      AD   E    K EK +   +   Q ++    P    IDE K+D+ L++++  DP+ + +PD  EL  LEA C  MGPLID++LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNH--------QHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVT------ADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDD-QPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNE 377
[Close]
BLAST of Signal transducing adapter molecule 2 vs. UniProt/SwissProt
Match: sp|O88811|STAM2_MOUSE (Signal transducing adapter molecule 2 OS=Mus musculus OX=10090 GN=Stam2 PE=1 SV=1)

HSP 1 Score: 246.899 bits (629), Expect = 6.715e-73
Identity = 142/375 (37.87%), Postives = 219/375 (58.40%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKN-IHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQK---RQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E ATNE  T +DW+ I+D+C++    P   K+CLK I+KR+ +  PH+ L+++ LL ACV N G+ F  E+ SR F  E++S  KN  H K  E+L  +M +WS E     ++  I+   K +++      +AG   + +    K    + + +E+ED+AKAI LSL+E +Q+    + LYP          P E+    K   +VRALYDFEA EDNELTFK GE+I  +D S+ +WW G NHRG G+FP+ FV+ D+  E +       A ++K +   +   +   + P    IDE K+D  L++++  DP  E +PD  +L  LE  C+ MGP+ID++LE++DR ++ L ELN  V+E+  LYN+L+ + 
Sbjct:   13 VEKATNEYNTTEDWSLIMDICDRVGSTPSGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRSVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAA--AKNGTSLNKNKEDEDIAKAIELSLQEQKQQYTETKALYP----------PAESQLNNKAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVE------TATVDKLNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPK-ESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVNEA 368
[Close]
BLAST of Signal transducing adapter molecule 2 vs. UniProt/SwissProt
Match: sp|Q5XHY7|STAM2_RAT (Signal transducing adapter molecule 2 OS=Rattus norvegicus OX=10116 GN=Stam2 PE=2 SV=1)

HSP 1 Score: 244.973 bits (624), Expect = 3.151e-72
Identity = 141/372 (37.90%), Postives = 221/372 (59.41%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKN-IHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E ATNE  T +DW+ I+D+C++    P   K+CLK I+KR+ +  PH+ L+++ LL ACV N G+ F  E+ SR F  E+++  KN  H K  E+L  +M +WS E     ++  I+   K +++      +AG   +++    K    + + +E+ED+AKAI LSL+E +Q+    YP     A+   P E+    K   +VRALYDFEA EDNELTFK GEII  +D S+ +WW G NHRG G+FP+ FV+ D+  E +       A ++K +   +   +   + P    IDE K+D  L++++  DP  + +PD  +L  LE  C+ MGP+ID++LE++DR ++ L ELN  V+E+ +LYN+L+ + 
Sbjct:   13 VEKATNEYNTTEDWSLIMDICDRVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKAMKEEGVTFPSAGSQTVSAA--AKNGASLNKNKEDEDIAKAIELSLQEQKQQ----YPET--KALCP-PAESQLSNKVARRVRALYDFEAVEDNELTFKHGEIITVLDDSDANWWEGENHRGAGLFPSSFVTTDLSTEVEA------ATVDKSNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPK-DPKPDSQDLLDLEDICQQMGPMIDEKLEEIDRRHSELSELNVKVLEALELYNKLVNEA 368
[Close]
BLAST of Signal transducing adapter molecule 2 vs. TrEMBL
Match: A0A4S2LPQ7 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007213 PE=4 SV=1)

HSP 1 Score: 303.138 bits (775), Expect = 2.713e-91
Identity = 181/436 (41.51%), Postives = 254/436 (58.26%), Query Frame = 1 
Query:   19 LANLIEIATNEKQTEDDWTKILDVCEK-GTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSREL-TGSEYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGN--RKV---VQGQEEEDLAKAIALSLKESEQKR-------------------------QNLYPSNINHAINKMP-TETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ---------GGGS--------MNRPGNYMWPQP 1176
            +  LIE  T+EK T+D W  IL +CE+ G++ PK CLK I KR+F+ NP++ LR+I LLDAC +N G+PF +E++SR F + IKS+  ++ +    +L  + +KW+ E  + SE      L  W++  +   Y      L  R  IK    R+V   ++ +EEE+LAKAIALSL+ES  KR                          NLYP     A + +P  +  P+K    +VRALYDFEAAEDNELTFKAGE+I+ +D S+E+WW GSNHRG+G+FPAQFV  + E       ES  +K +  +  I   P    ++P+   +D  K+DECL +I   DPTGE RPDP EL +LEA+C  M PL+D ELEKVD+   ML ELN+ ++++FQ+Y++LM++         GGG+        M   G Y  PQP
Sbjct:    1 MEQLIEQCTSEKNTQDQWDLILRICEEYGSKEPKACLKAIGKRIFHKNPNVSLRAITLLDACSKNCGKPFNREIASRDFTHSIKSRFSSLQRIPSVKLTEVFEKWAEEFKSDSELALAASLYSWVKSEH---YDVIRHLLEDRQAIKAGSARQVAAQLKAREEEELAKAIALSLQESGNKRPAESGPSRTTQPNTATTTASSNLGKSNLYP---EFAASTLPRAQAAPVKG---RVRALYDFEAAEDNELTFKAGELIVLLDDSDENWWRGSNHRGEGLFPAQFVKCETE-------ESPSSKKKDLNGPITETPKL--SKPVQ--LDAKKLDECLNLISMVDPTGEFRPDPPELPQLEAECNAMAPLVDPELEKVDKRVLMLSELNQRLLDAFQMYHDLMSEPPPLSAPYYGGGAIPTGAAGYMPPMGAYGAPQP 416
[Close]
BLAST of Signal transducing adapter molecule 2 vs. TrEMBL
Match: A0A4S2LQ72 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007213 PE=4 SV=1)

HSP 1 Score: 303.138 bits (775), Expect = 2.969e-91
Identity = 181/439 (41.23%), Postives = 256/439 (58.31%), Query Frame = 1 
Query:   10 LMSLANLIEIATNEKQTEDDWTKILDVCEK-GTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSREL-TGSEYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGN--RKV---VQGQEEEDLAKAIALSLKESEQKR-------------------------QNLYPSNINHAINKMP-TETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ---------GGGS--------MNRPGNYMWPQP 1176
            + S+ + IE  T+EK T+D W  IL +CE+ G++ PK CLK I KR+F+ NP++ LR+I LLDAC +N G+PF +E++SR F + IKS+  ++ +    +L  + +KW+ E  + SE      L  W++  +   Y      L  R  IK    R+V   ++ +EEE+LAKAIALSL+ES  KR                          NLYP     A + +P  +  P+K    +VRALYDFEAAEDNELTFKAGE+I+ +D S+E+WW GSNHRG+G+FPAQFV  + E       ES  +K +  +  I   P    ++P+   +D  K+DECL +I   DPTGE RPDP EL +LEA+C  M PL+D ELEKVD+   ML ELN+ ++++FQ+Y++LM++         GGG+        M   G Y  PQP
Sbjct:    1 MTSIRSRIEQCTSEKNTQDQWDLILRICEEYGSKEPKACLKAIGKRIFHKNPNVSLRAITLLDACSKNCGKPFNREIASRDFTHSIKSRFSSLQRIPSVKLTEVFEKWAEEFKSDSELALAASLYSWVKSEH---YDVIRHLLEDRQAIKAGSARQVAAQLKAREEEELAKAIALSLQESGNKRPAESGPSRTTQPNTATTTASSNLGKSNLYP---EFAASTLPRAQAAPVKG---RVRALYDFEAAEDNELTFKAGELIVLLDDSDENWWRGSNHRGEGLFPAQFVKCETE-------ESPSSKKKDLNGPITETPKL--SKPVQ--LDAKKLDECLNLISMVDPTGEFRPDPPELPQLEAECNAMAPLVDPELEKVDKRVLMLSELNQRLLDAFQMYHDLMSEPPPLSAPYYGGGAIPTGAAGYMPPMGAYGAPQP 419
[Close]
BLAST of Signal transducing adapter molecule 2 vs. TrEMBL
Match: A0A5J4NBJ9 (Signal transducing adaptor molecule OS=Paragonimus westermani OX=34504 GN=DEA37_0006418 PE=4 SV=1)

HSP 1 Score: 302.753 bits (774), Expect = 2.309e-90
Identity = 174/412 (42.23%), Postives = 246/412 (59.71%), Query Frame = 1 
Query:   28 LIEIATNEKQTEDDWTKILDVCEK-GTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSREL-TGSEYDCINELNKWLQDTY--PIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKR------------QNLYPSNINHAI---------NKMP--TETVPLKKQL----PKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPD--SYSTRPITPV-IDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNY 1161
             +E  T+EK  +D W  IL VCE+  ++ PK CLK+I KRLFN NP++ LR+I LLDAC +N G+PF +E++SR FV  IK +  ++ +    +L  + +KW+ E  + SE      L  W++  +   I +   D +       + N   +Q +EEE+LAKA+A+SLKESE KR            Q++  ++   A          N  P  T++VP+K        +VRALYDFEAAEDNELTFKAGE+II +D S+E+WW GSNHRG+G+FPAQFV  + E              E   +  +H P+  S +T P   V +D +K+DECLR+I   DPTGE RPDP EL +LEA+C  M PL+D ELEKVD+   ML +LN+ ++++FQLY++LM+Q    +   G Y
Sbjct:   50 FVEQCTSEKNIQDKWDLILHVCEEYASKEPKACLKVIGKRLFNKNPNVSLRAITLLDACSKNCGKPFNREIASRDFVQLIKGRFTSLQRIPSVKLAEVFEKWAEEFQSDSELALAAGLYNWVRTEHNDVIRHLHEDRQAIKTGAARQNAAYLQAKEEEELAKALAMSLKESEAKRPLQSDANAARTAQSVAKASTAPATKTNLTENKTNLYPNFTDSVPVKSAFTPAKSRVRALYDFEAAEDNELTFKAGELIIVLDDSDENWWRGSNHRGEGLFPAQFVKRETE--------------ETTVSQTDHVPNVASPTTEPPAQVRLDGNKLDECLRLISMVDPTGEFRPDPPELPQLEAECNAMAPLVDPELEKVDKRLLMLSDLNQRLLDAFQLYHDLMSQSNAPVCGTGYY 447
[Close]
BLAST of Signal transducing adapter molecule 2 vs. TrEMBL
Match: A0A2H1BXJ5 (SH3 domain protein OS=Fasciola hepatica OX=6192 GN=D915_13285 PE=4 SV=1)

HSP 1 Score: 296.975 bits (759), Expect = 2.402e-90
Identity = 167/415 (40.24%), Postives = 245/415 (59.04%), Query Frame = 1 
Query:   34 EIATNEKQTEDDWTKILDVCEK-GTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSREL-TGSEYDCINELNKWLQDTYP--IIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQK--------------------------RQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ--------GGGSMNRPGNYM 1164
            E  T+EK T+D W  IL +CE+ G++ PK CLK I KR+F+ NP++ +R++ LLDAC +N G+ F +EL+SR F   +KS+  N+ +    +L  + +KW+ E  + SE      L  W++  +   I +   D +++    ++ N   +Q +EEE+LA+AIALSLKESE K                           Q  YP+  N    +     V + K   +VRALYDFEAAEDNELTFKAGE+I+ +D S+E+WW GSNHRG+G+FPAQFV  ++E+ A          I   +A+    P + S    T  +D +K+DECLR+I   DPTGE RPDP EL++LE +C  M PL+D ELEKVD+   ML +LN+ ++++FQ+Y++LM++        GG S +  G Y+
Sbjct:    6 EQCTSEKNTQDQWDLILRICEEYGSKEPKACLKAIGKRVFHKNPNVSIRAVTLLDACSKNCGKVFNRELASRDFSQLVKSRFANLQRIPSIKLTEVFEKWAEEFKSDSELALAASLYSWVKSEHGDIIKHLHEDRQVSKSGQVRQNAAKLQAKEEEELAQAIALSLKESENKPSARVTSPHAPAPPSLAQSGTSVSDRHQVSYPNFANGPTAQPAVSNVAVSKG--RVRALYDFEAAEDNELTFKAGELIVLLDDSDENWWRGSNHRGEGLFPAQFVKRELEDSA---------VISPVAASAPESPITGSLAKTTVQLDAAKMDECLRLINMVDPTGEFRPDPPELAQLEVECNAMAPLVDPELEKVDKRVLMLSDLNQQLLDAFQMYHDLMSRPTLSQVPSGGTSTSAAGYYI 409
[Close]
BLAST of Signal transducing adapter molecule 2 vs. TrEMBL
Match: A0A4E0QY90 (Signal transducing adaptor molecule (Fragment) OS=Fasciola hepatica OX=6192 GN=D915_008972 PE=4 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 5.868e-90
Identity = 170/423 (40.19%), Postives = 251/423 (59.34%), Query Frame = 1 
Query:   10 LMSLANLIEIATNEKQTEDDWTKILDVCEK-GTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSREL-TGSEYDCINELNKWLQDTYP--IIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQK--------------------------RQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ--------GGGSMNRPGNYM 1164
            ++SL+ L E  T+EK T+D W  IL +CE+ G++ PK CLK I KR+F+ NP++ +R++ LLDAC +N G+ F +EL+SR F   +KS+  N+ +    +L  + +KW+ E  + SE      L  W++  +   I +   D +++    ++ N   +Q +EEE+LA+AIALSLKESE K                           Q  YP+  N    +     V + K   +VRALYDFEAAEDNELTFKAGE+I+ +D S+E+WW GSNHRG+G+FPAQFV  ++E+ A          I   +A+    P + S    T  +D +K+DECLR+I   DPTGE RPDP EL++LE +C  M PL+D ELEKVD+   ML +LN+ ++++FQ+Y++LM++        GG S +  G Y+
Sbjct:   20 VLSLS-LTEQCTSEKNTQDQWDLILRICEEYGSKEPKACLKAIGKRVFHKNPNVSIRAVTLLDACSKNCGKVFNRELASRDFSQLVKSRFANLQRIPSIKLTEVFEKWAEEFKSDSELALAASLYSWVKSEHGDIIKHLHEDRQVSKSGQVRQNAAKLQAKEEEELAQAIALSLKESENKPSARVTSPHAPAPPSLAQSGTSVSDRHQVSYPNFANGPTAQPAVSNVAVSKG--RVRALYDFEAAEDNELTFKAGELIVLLDDSDENWWRGSNHRGEGLFPAQFVKRELEDSA---------VISPVAASAPESPITGSLAKTTVQLDAAKMDECLRLINMVDPTGEFRPDPPELAQLEVECNAMAPLVDPELEKVDKRVLMLSDLNQQLLDAFQMYHDLMSRPTLSQVPSGGTSTSAAGYYI 430
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Cavefish
Match: stam (signal transducing adaptor molecule [Source:NCBI gene;Acc:103028487])

HSP 1 Score: 243.817 bits (621), Expect = 9.878e-73
Identity = 151/385 (39.22%), Postives = 223/385 (57.92%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPII------YAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQN----LYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRP-ITPV-IDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PKECL+ I++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ +     +   I+ + K L++   T+P +       A     L +++P     K    +EEEDLAKAI LSLKE   + Q     LYPS      N + T   P  +   KVRA+YDFEAAEDNELTFK+GEII  +D S+ +WW G  ++G G+FP+ FV+ D+  E +        K EK +   + +    +  P   PV IDE K+D+ L++I+ ADPT   + D  EL +LE  C  MGPLIDQ+LE +DR ++ L ELN  V+E+  LY +LM +
Sbjct:   13 VEKATSEMNTAEDWGLILDICDKIGQSRTGPKECLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSREFASEVSNVLNKGHPKVCEKLKALMVEWAEDFRNDPQLSLISAMIKNLREQGVTFPAVGSQAAEQAKASPALVAKDPATSTNK----KEEEDLAKAIELSLKEQRVQPQTSLSGLYPS-----ANSLLTSHKPEGR---KVRAIYDFEAAEDNELTFKSGEIITILDDSDPNWWKGETYQGVGLFPSNFVTADLTAEPEMM------KTEKKTVQFSEEIKVETIEPEPEPVYIDEEKMDQLLQMIQSADPTDN-QSDSCELLQLEGACNQMGPLIDQKLEDIDRKHSELSELNVKVMEALSLYAKLMNE 378
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Cavefish
Match: stam2 (signal transducing adaptor molecule 2 [Source:NCBI gene;Acc:103030763])

HSP 1 Score: 240.35 bits (612), Expect = 1.458e-71
Identity = 143/377 (37.93%), Postives = 218/377 (57.82%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEK--GTQN-PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS--MDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPV-IDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E  TNE  T +DW  I+D+C++   TQN  K+CL+ I+KR  +  PH+ ++++ LL ACV N G+ F  E+ SR F +E++S     H K +E+L  ++ +W+ E     +   I    K L++   T+P          +S  P        +  +E+DLAKAI LSL+E +Q+ +    +      N  P  T  +K+   KVRALYDFEAAEDNELTFKAGE+++ +D S+ +WW G NHRG G+FP+ FV+  ++ E E D + E       +    +  +P+        PV IDE K+D+ L ++++ DP  +  PD AEL  LE  C  M PLID++LE++DR ++ L ELN  V+E+ +LYN+LM + 
Sbjct:   13 VEKVTNEHNTAEDWGLIMDICDRVGTTQNGAKDCLRSIVKRANHKVPHVAMQALTLLGACVANSGKIFHLEICSREFASEVRSLLNKAHPKVIEKLKGLLVEWADEFQKDPQLSLIGATIKSLKEEGVTFPSSGTQSSSSKSSSAP-----ATTRASDEDDLAKAIELSLQEQKQQAE----TRPIFVTNDPPYNTNSVKESR-KVRALYDFEAAEDNELTFKAGEVVLVLDDSDPNWWKGENHRGVGLFPSNFVTTNLNAEPEPDSYAEKTAVPEAEPVVEVKAEPE--------PVHIDEEKMDKTLYILQNTDP-ADSAPDSAELVTLEGACAQMNPLIDEKLEEIDRKHSELSELNVKVLEALELYNQLMNEA 370
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Cavefish
Match: ENSAMXT00000037557.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000043.1:1019441:1027754:-1 gene:ENSAMXG00000029505.1 transcript:ENSAMXT00000037557.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.0409 bits (214), Expect = 1.646e-20
Identity = 39/70 (55.71%), Postives = 53/70 (75.71%), Query Frame = 1 
Query:  625 VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS--MDVENEADKFGESNRAK 828
            +RALYDFEAAEDNELTFKAGE+++ +D S+ +WW G NHRG G+FP+ FV+  ++ E E D + E   A+
Sbjct:    9 MRALYDFEAAEDNELTFKAGEVVLVLDDSDPNWWKGENHRGVGLFPSNFVTTNLNAEPEPDSYAEKTLAR 78
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Cavefish
Match: si:dkey-40c11.2 (si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-300])

HSP 1 Score: 62.3882 bits (150), Expect = 1.094e-9
Identity = 26/51 (50.98%), Postives = 39/51 (76.47%), Query Frame = 1 
Query:  625 VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRG-QGMFPAQFV 774
            VRALYD++A ++NEL+F+ G+II DV+  ++ WW G +  G QG+FPA +V
Sbjct:  651 VRALYDYQAEDENELSFEPGDIIRDVETVDKAWWRGFSKDGRQGLFPANYV 701
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Cavefish
Match: grap2b (GRB2 related adaptor protein 2b [Source:ZFIN;Acc:ZDB-GENE-040426-1485])

HSP 1 Score: 57.3806 bits (137), Expect = 7.818e-9
Identity = 25/57 (43.86%), Postives = 36/57 (63.16%), Query Frame = 1 
Query:  604 LKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFV 774
            ++  L +VRAL+DF A E +EL F AG+II  VD  + +WW G     +G+FPA + 
Sbjct:  173 VQTSLTQVRALFDFRAEEKDELDFNAGDIIEVVDRVDSYWWMGQLRGRRGLFPANYT 229
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Sea Lamprey
Match: stam (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:ZFIN;Acc:ZDB-GENE-031118-123])

HSP 1 Score: 240.736 bits (613), Expect = 2.164e-73
Identity = 155/394 (39.34%), Postives = 218/394 (55.33%), Query Frame = 1 
Query:   34 EIATNEKQTEDDWTKILDVCEK---GTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQDTYPIIYAAGDD--ELNSRNPI---KGNRKVVQGQEEEDLAKAIALSLKESEQ--------KRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMD--------VENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRH-YNMLVELNRNVIESFQLYNELMTQGGG 1137
            E AT+E  T +DW  ILDVC+K     Q PK+CL+  +KR+ N  PH+ ++++ LL ACV N G+ F  E+ SR F NE+ +     H K  E+L  +M +W+ E     +   I  + K L+D      A G    E    +P    K    V   QEE+DLAKAI LSLKE+             +LYP+        +        +   KVRA+YDFEAAEDNELTF+AG++I  +D S+ +WW G  H+G G+FP+ FVS D        ++ E      S+  K+E    AI  +P+     P+   IDE K+D  LR+++ ADP  E RPDP EL  LE  C+ MGPLIDQ+LE +DR  ++ L ++N  V+E+F+LYN+LM +  G
Sbjct:   12 EKATSELNTTEDWALILDVCDKIGHSPQGPKDCLRATMKRVNNKVPHVAMQALTLLGACVSNCGKIFHLEVCSREFANEVNNVLNKAHPKVGEKLKALMMEWAEEFKNDPQLSLIAAMIKNLKDQGVAFPAPGSQAAEQAKASPALVPKDPGTVTAKQEEDDLAKAIELSLKETTGLAVVAPVGAGGSLYPTATALGGAALARSAAGDAR---KVRAMYDFEAAEDNELTFRAGDVISVLDDSDPNWWKGETHKGSGLFPSNFVSADLTAEPEAPIKTEKKTVQFSDEVKVE----AIEPEPE-----PL--FIDEGKMDTLLRMLQSADPADE-RPDPPELLYLEESCQHMGPLIDQKLEDIDRRKHSELSDINVKVMEAFELYNQLMNEAPG 390
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Sea Lamprey
Match: stam (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:ZFIN;Acc:ZDB-GENE-031118-123])

HSP 1 Score: 216.083 bits (549), Expect = 2.336e-64
Identity = 134/382 (35.08%), Postives = 212/382 (55.50%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQNP---KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSEYDCI-NELNKWLQDTYPIIYAAGDDELNS---------RNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITP---VIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  + +DW+ I D+C +   +P   K+CL  I+KR+ +  P + + S+ LL+ACV + G+PF  ++ S+ F +E+    +  H K  +RL  M+ +W  +       C+   + K L+D      A G  E+ +         + P KG   VV+ +EE+DLAKAI LS+KE +Q          +   + +          L KVRALYDFEAAEDNELTF+AGEI+  +D S+ +WW G    G G+FP+ FV+ D+  E +   ++   +I+        +P+   T    P    I+E ++D+ L +++  DP  + RP+ AEL +LE  C  MGPLIDQ+LE++DR ++ L E+N N+ ++  LYN LM +
Sbjct:   14 VERATSESNSTEDWSLITDICNQVEASPNGSKDCLMAIMKRVQHKVPLVAMHSLTLLEACVSSCGKPFQVQICSKEFADEVTKVLEKAHPKVCDRLKAMLVEWWEKFKNDSQMCLLFFIIKNLKDKEIEFPALGSKEMEAAKAGFGSPAKEPSKG---VVRSKEEDDLAKAIELSIKEQKQYPSLSGVGGSSSTTSSV-------GPSLRKVRALYDFEAAEDNELTFRAGEILTVLDDSDANWWKGETESGLGLFPSNFVTADLTAEPES-AKAMTCRIQYS----RDEPEEVPTAEPDPEPLAINEERMDQVLHMLQSLDPKDD-RPESAELLRLEESCHQMGPLIDQKLEEIDRKHSELSEMNTNLGDAISLYNRLMKE 379
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Sea Lamprey
Match: grb2a (growth factor receptor-bound protein 2a [Source:ZFIN;Acc:ZDB-GENE-041121-1])

HSP 1 Score: 62.003 bits (149), Expect = 3.706e-11
Identity = 30/66 (45.45%), Postives = 42/66 (63.64%), Query Frame = 1 
Query:  610 KQLP-----KVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVEN 792
            +QLP     +V+AL+DFE  ED EL F+ G+ I  VD S+ +WW GS H   GMFP  +V++  +N
Sbjct:  152 EQLPQQAATRVQALFDFEPQEDGELGFRRGDFITVVDSSDPNWWKGSCHGRAGMFPRNYVTLAKDN 217
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Sea Lamprey
Match: DBNL (drebrin like [Source:HGNC Symbol;Acc:HGNC:2696])

HSP 1 Score: 58.151 bits (139), Expect = 2.227e-9
Identity = 23/53 (43.40%), Postives = 38/53 (71.70%), Query Frame = 1 
Query:  625 VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRG-QGMFPAQFVSM 780
             RALYD++AA+D E++F  G++I +++  ++ WW GS   G +GMFPA +V +
Sbjct:  302 ARALYDYQAADDTEISFDPGDLISNIEQIDDGWWNGSGPDGSRGMFPANYVEL 354
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Sea Lamprey
Match: cttn (cortactin [Source:ZFIN;Acc:ZDB-GENE-040715-3])

HSP 1 Score: 51.6026 bits (122), Expect = 3.794e-7
Identity = 22/67 (32.84%), Postives = 39/67 (58.21%), Query Frame = 1 
Query:  580 KMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSM 780
            K+  ET P         A+YD++ A D+E++F+  +II +++  +E WW G  +   G+FPA +V +
Sbjct:  492 KLQNETFPSSPAGATAVAIYDYQKAGDDEISFEPDDIITNIECLDEGWWRGECNGQVGIFPANYVEL 558
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Yeast
Match: HSE1 (Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994])

HSP 1 Score: 93.2041 bits (230), Expect = 1.227e-20
Identity = 71/283 (25.09%), Postives = 134/283 (47.35%), Query Frame = 1 
Query:   13 MSLANLIEIATNEKQTEDDWTKILDVCEKGTQNP----KECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKS--KSKNIHQKALERLCFMMKKWSRELTGSEYDCINELNKWLQDTYPIIYAAGD--DELNSRNPIKGNRKV---------VQGQEEEDLAKAIALSLKESEQKRQ---------NLYPSNINHAINKM--PTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS 777
            + + N +  AT+ K   D+W  ILDVC+   ++P    +E + LI KRL   + +++LR++ L  +  +N G    +E+SS+ F + + +  +S ++H          +KK       +  D + +L+   +D  P + A GD  D++  + P      V             ++E+L KA+ +SL E E++++          + P        +   P   +P +  + +VRALYD    E +EL+F+ G++I  ++     WW G+     G+FP  +V+
Sbjct:    6 IKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDANVILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSVH--------ITLKK-------AVTDVVKQLSDSFKDD-PSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMSTQADNSDDEELQKALKMSLFEYEKQKKLQEQEKESAEVLPQQQQQHQQQNQAPAHKIPAQTVVRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVT 272
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Yeast
Match: ABP1 (Actin-binding protein of the cortical actin cytoskeleton; important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; inhibits barbed-end actin filament elongation; phosphorylation within its Proline-Rich Regio, mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences; mammalian homolog of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa) [Source:SGD;Acc:S000000684])

HSP 1 Score: 55.4546 bits (132), Expect = 1.687e-8
Identity = 24/59 (40.68%), Postives = 39/59 (66.10%), Query Frame = 1 
Query:  610 KQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHR--GQGMFPAQFVSM 780
            K+ P   A YD++AAEDNELTF   + II+++  ++ WW G   +   +G+FP+ +VS+
Sbjct:  532 KENPWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSL 590
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Yeast
Match: VPS27 (Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289])

HSP 1 Score: 50.0618 bits (118), Expect = 7.544e-7
Identity = 34/90 (37.78%), Postives = 48/90 (53.33%), Query Frame = 1 
Query:   19 LANLIEIATNEKQTEDDWT-----KILDVCEKGTQNPKECLKLILKRLFNI--NPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIK 267
            L  LIE AT+E     D       +I DV      NPK+ ++ I KR+ N   NP+  L S  L + CV+N G PF KE+ SR F++ ++
Sbjct:    9 LDALIEQATSESIPNGDLDLPIALEISDVLRSRRVNPKDSMRCIKKRILNTADNPNTQLSSWKLTNICVKNGGTPFIKEICSREFMDTME 98
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Yeast
Match: YSC84 (Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058])

HSP 1 Score: 46.9802 bits (110), Expect = 6.058e-6
Identity = 22/78 (28.21%), Postives = 41/78 (52.56%), Query Frame = 1 
Query:  559 NINHAINK--MPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEH--WWYGSNHRGQGMFPAQFVSM 780
            +++H ++K  +  E+       P   ALY+F   +  +L FK G++I  +  S+    WW G  +  +G+FPA +V +
Sbjct:  390 DLSHKMSKTGLGNESTATNSATPTAVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTNGKEGIFPANYVRV 467
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Yeast
Match: LSB1 (Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication [Source:SGD;Acc:S000003368])

HSP 1 Score: 45.8246 bits (107), Expect = 8.183e-6
Identity = 20/50 (40.00%), Postives = 32/50 (64.00%), Query Frame = 1 
Query:  625 VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFV 774
            V ALYDFEA +D +L+ K G+ I  ++  +  W+ G ++   G+FPA +V
Sbjct:   58 VEALYDFEAQQDGDLSLKTGDKIQVLEKISPDWYRGKSNNKIGIFPANYV 107
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Nematostella
Match: EDO46357 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQF8])

HSP 1 Score: 184.882 bits (468), Expect = 5.385e-51
Identity = 147/489 (30.06%), Postives = 235/489 (48.06%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEK---------------GTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKS-KSKNIHQKALERLCFMMKKWSRELTGSEYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQG--------------------------QEEEDLAKAIALSLKESE---QKRQNLYPSNINHAINKMPTETVPLKK----QLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDV---ENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELM--------TQGGGSMNRPGNYMWPQPMXXXXXXXXLHH----PHHAQFTSIPMQDPSQMMSRMMNENVNPAAP 1305
            +E AT+E  T +DW  I+++C+K               G + PK+ L+ I+KR+ + NPHI ++++ LL ACV N G+ F  E+ SR FV+E KS      H K +++   ++K+W              +N + +D    + +   ++L +     G   VVQ                           QEEEDLA+AI LSL++SE    K  +LYPS       K+P+ T P+++    +  KVRALYDFEAAEDNELTFK G+II  +D S+  WW G    G G+FP+ FV+ D+   ++   +  +  + K  + + A   Q +    + + P IDE K++ECL +++ A   G+   + A +  LE  C  M  ++++++EK    +  L  LN   +++  LY +LM        T       RP  Y + QP  V        +    P + Q + +P  +PSQ        ++ P  P
Sbjct:   14 VEKATSELNTTEDWQIIMEICDKIPRSPNGLIFTREGKGEERPKDALRSIMKRVIHRNPHIAMQALTLLSACVNNCGKVFHLEICSRDFVSEAKSILLSRTHPKVMDKFKELIKEW--------------VNMFKEDPQLSLISVMCEQLKTEGVDLG---VVQTTSKTSSSSSSSMKSSPASSSAASSLSQEEEDLARAIQLSLQDSEGSKPKVSSLYPSA------KVPSPT-PIRRVKMQERKKVRALYDFEAAEDNELTFKTGDIISILDDSDASWWKGETPNGTGLFPSNFVTSDLSEPQSPTVRAEKVEKKKKVRWADAAARQENLPKEQVVKPKIDEDKIEECLSMLKAASVEGDDEQEDA-IIDLEYACHNMEEIVNKKIEKSKAKHQDLSSLNEQYLQALALYQKLMKEPLPIPPTPTYNYSTRPQAYGY-QPTSVAPPQYQQIYGPPPPAYPQASQLPYSEPSQAAMSAGYSSLGPGQP 476
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Nematostella
Match: EDO44864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUJ2])

HSP 1 Score: 67.781 bits (164), Expect = 1.994e-12
Identity = 39/139 (28.06%), Postives = 75/139 (53.96%), Query Frame = 1 
Query:   16 SLANLIEIATNEKQTEDDWTKILDVCEKGTQ---NPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSEYDCINELN-KWLQDTYPIIYAAG 420
            +   L+E AT++ Q E DW  IL +C+   Q   +PK  +  I K++F+ NPH+   ++ +L+AC++N G     E++++ F++E+++  KN      ++   +++ WS           NE   K +QDT+ ++   G
Sbjct:    9 TFTGLLERATSQLQLEPDWATILQICDSVRQQDVSPKFAVSAIKKKMFDRNPHVAKYALTVLEACMKNCGSIIHDEIATKDFMDEMRNLIKNGADPVKDKALGLIQTWSHAFR-------NEPKYKIVQDTFNLMKMEG 140
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Nematostella
Match: EDO31290 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYD1])

HSP 1 Score: 55.8398 bits (133), Expect = 1.170e-8
Identity = 25/64 (39.06%), Postives = 39/64 (60.94%), Query Frame = 1 
Query:  592 ETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQ-GMFPAQFVSM 780
            E  P +       ALYD++ A+DNE+TF   +II +++  +E WW G+   G+ GMFPA +V +
Sbjct:  180 ENAPAEDTGVTATALYDYQQADDNEITFDPDDIITNIEQIDEGWWRGTGPDGRHGMFPANYVEI 243
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Nematostella
Match: EDO42689 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K6])

HSP 1 Score: 54.6842 bits (130), Expect = 5.930e-8
Identity = 27/52 (51.92%), Postives = 37/52 (71.15%), Query Frame = 1 
Query:  625 VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGS--NHRGQGMFPAQFV 774
            V ALYD+EAAED+EL+FKAGEI+  +   ++  W     NHR  G+FPA++V
Sbjct:  386 VLALYDYEAAEDDELSFKAGEIVTKLSERDDQGWCRGRINHR-TGLFPAEYV 436
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Nematostella
Match: EDO38076 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE08])

HSP 1 Score: 51.2174 bits (121), Expect = 1.749e-7
Identity = 26/64 (40.62%), Postives = 42/64 (65.62%), Query Frame = 1 
Query:  589 TETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSN-HRGQ-GMFPAQFV 774
            ++ + LK  +  V+AL+DFEA E+ E++FK G+ I  +D S+ +WW G     G+ GMFP+ +V
Sbjct:  123 SQHIVLKDMMEAVQALFDFEAQEEGEVSFKRGDCIEVIDNSDVNWWRGKVLTTGEIGMFPSNYV 186
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Medaka
Match: stam (signal transducing adaptor molecule [Source:NCBI gene;Acc:101162787])

HSP 1 Score: 243.817 bits (621), Expect = 8.505e-73
Identity = 149/382 (39.01%), Postives = 225/382 (58.90%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEKGTQN---PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPII------YAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQK-RQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPIT-PV-IDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQ 1128
            +E AT+E  T +DW  ILD+C+K  Q+   PKECL+ +++R+ + +PH+ ++++ LL ACV N G+ F  E+ SR F +E+ +     H K  E+L  +M +W+ +     +   I+ + K L++   T+PI+       A     L +++P     K    +EEEDLAKAI LSLKE  Q+   +LYP N +  ++         K    KVRA+YDFEAAEDNELTFK+GEII  +D S+ +WW G  ++G G+FP+ FV+ D+  E +        K+EK S   + +    +  P   PV IDE K+D+ L++I+ ADPT   + D  EL +LE  C  MGPLIDQ+LE +DR ++ L +LN  V+E+  LY +LM +
Sbjct:   13 VEKATSEMNTAEDWGLILDICDKIGQSRTGPKECLRSVMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSREFASEVSNVLNKGHPKVCEKLKALMVEWAEDFRNDPQLSLISAMIKNLREQGVTFPIVGSQAAEQAKASPALVAKDPATSTNK----KEEEDLAKAIELSLKEQRQQPLASLYP-NASSLVSSH-------KSDGRKVRAIYDFEAAEDNELTFKSGEIITILDDSDPNWWKGETYQGIGLFPSNFVTADLSAEPEMM------KMEKKSVQFSEEIQVETIEPQQEPVFIDEDKMDQLLQMIQSADPTDN-QSDSVELLQLEGACNQMGPLIDQKLEDIDRKHSELSDLNVKVMEALSLYAKLMNE 375
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Medaka
Match: stam2 (signal transducing adaptor molecule 2 [Source:NCBI gene;Acc:101159231])

HSP 1 Score: 236.113 bits (601), Expect = 3.973e-70
Identity = 148/386 (38.34%), Postives = 213/386 (55.18%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEK-GTQN--PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLP------------KVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E ATNE  T DDW  ILD+C+K GT +   K+ LK I+KR+ +  PH+ ++++ LL ACV N G+ F  E+ SR F +E++S     H K  ERL  +M +W+ +     +   I+   K L++   T+P   + G     S         V +  +++DLAKAI LSL+E +Q+                  ET PL    P            KVRALYDFEAAEDNE+TFKAGE+II +D S+ +WW G NH+G G+FP+ FVS ++  E +         I + +   NH        P    IDE K+D  L ++ +ADP  +  PD AEL +LEA C  M PLID++L+ +DR ++ L ELN  V+E+ +LYN+LM + 
Sbjct:   13 VEKATNENNTTDDWALILDICDKIGTTSNGAKDSLKSIMKRVNHKVPHVAMQALNLLGACVSNCGKIFHLEICSRDFASEVRSVLSRAHPKVCERLKALMVEWAEDFQKDPQLSLISATIKSLKEEGITFPTASSQGSTTKVS------TPAVSKPSDDDDLAKAIELSLQEQKQQ-----------------AETRPLTSDPPSYSNGGGGQEVRKVRALYDFEAAEDNEMTFKAGELIIILDDSDPNWWKGENHKGVGLFPSNFVSTNLNAEPEPVAFVENTVIPEET---NHD---VKVEPEPVYIDELKMDRTLALLRNADP-ADPTPDSAELLQLEASCEQMNPLIDEKLQGIDRSHSELSELNVKVLEALELYNKLMNEA 368
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Medaka
Match: stam2 (signal transducing adaptor molecule 2 [Source:NCBI gene;Acc:101159231])

HSP 1 Score: 234.572 bits (597), Expect = 1.366e-69
Identity = 152/389 (39.07%), Postives = 219/389 (56.30%), Query Frame = 1 
Query:   31 IEIATNEKQTEDDWTKILDVCEK-GTQN--PKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGS-EYDCINELNKWLQD---TYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLP------------KVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVS--MDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPV-IDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQG 1131
            +E ATNE  T DDW  ILD+C+K GT +   K+ LK I+KR+ +  PH+ ++++ LL ACV N G+ F  E+ SR F +E++S     H K  ERL  +M +W+ +     +   I+   K L++   T+P   + G     S         V +  +++DLAKAI LSL+E +Q+                  ET PL    P            KVRALYDFEAAEDNE+TFKAGE+II +D S+ +WW G NH+G G+FP+ FVS  ++ E E   F E N    E+ +  +  +P+        PV IDE K+D  L ++ +ADP  +  PD AEL +LEA C  M PLID++L+ +DR ++ L ELN  V+E+ +LYN+LM + 
Sbjct:   13 VEKATNENNTTDDWALILDICDKIGTTSNGAKDSLKSIMKRVNHKVPHVAMQALNLLGACVSNCGKIFHLEICSRDFASEVRSVLSRAHPKVCERLKALMVEWAEDFQKDPQLSLISATIKSLKEEGITFPTASSQGSTTKVS------TPAVSKPSDDDDLAKAIELSLQEQKQQ-----------------AETRPLTSDPPSYSNGGGGQEVRKVRALYDFEAAEDNEMTFKAGELIIILDDSDPNWWKGENHKGVGLFPSNFVSTNLNAEPEPVAFVE-NTVIPEETNHDVKVEPE--------PVYIDELKMDRTLALLRNADP-ADPTPDSAELLQLEASCEQMNPLIDEKLQGIDRSHSELSELNVKVLEALELYNKLMNEA 368
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Medaka
Match: hgs (hepatocyte growth factor-regulated tyrosine kinase substrate [Source:NCBI gene;Acc:101168120])

HSP 1 Score: 60.4622 bits (145), Expect = 3.654e-9
Identity = 37/139 (26.62%), Postives = 70/139 (50.36%), Query Frame = 1 
Query:   16 SLANLIEIATNEKQTEDDWTKILDVCE---KGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSEYDCINELN-KWLQDTYPIIYAAG 420
            +   L++ AT++   E DW  IL +C+   +G    K  +  I K+L + NPH+ L ++ +L++ V+N G+    E++S+  + E+K   K        ++ ++++ W+           NE   K +QDTY I+   G
Sbjct:    7 TFERLLDKATSQLLLETDWESILQICDLIRQGDAQAKNAIAAIKKKLNDKNPHVALYALEVLESVVKNCGQTVHDEVASKQTMEELKELLKQTEPNVRNKILYLIQAWAHAFR-------NEPKYKVVQDTYQIMKVEG 138
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Medaka
Match: grap2a (growth factor receptor-bound protein 2 [Source:NCBI gene;Acc:101165394])

HSP 1 Score: 57.3806 bits (137), Expect = 1.425e-8
Identity = 46/136 (33.82%), Postives = 60/136 (44.12%), Query Frame = 1 
Query:  421 DDELNSRNPIKGNRKVVQGQEEED-LAKAIALSLKE-SEQ------KRQNL--YPSNINHAINKMPTETV--PLKKQ----LPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSM 780
            D   NSR+P     K     E+ +  A A+A S +  SEQ      KR  L      I H     P      P + Q     P VRALYDF A E +EL F  G++I  +D S+  WW G      G+FPA +  +
Sbjct:  147 DGSSNSRSPASAQVKRASLPEQRNPAAAAVASSTRRASEQTPNQLMKRSGLEERAHTIGHTGRNSPASMTYPPQRAQQQASAPMVRALYDFTAEEADELGFCVGDVIEVMDRSDPSWWRGRLQGRTGLFPANYTVL 282
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Planmine SMEST
Match: SMESG000033040.1 (SMESG000033040.1)

HSP 1 Score: 1167.53 bits (3019), Expect = 0.000e+0
Identity = 565/568 (99.47%), Postives = 565/568 (99.47%), Query Frame = 1 
Query:   13 MSLANLIEIATNEKQTEDDWTKILDVCEKGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSEYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPMXXXXXXXXLHHPHHAQFTSIPMQDPSQMMSRMMNENVNPAAPQSVLPGHHDPMLYQTMNYYGNMNAATAAQNTDIMYGSAGPGAAAAQLPFGPKQTIQQLPPGSSYHPTMSNVTQKSNFPSTTHNNSSGLNAQDYHHRSLPVQNNYSESSFQPPVAMINQPQVSYVQSDQTFPTADGFH 1716
            MSLANLIEIATNEKQTEDDWTKILDVCEKGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGE FTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSEYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINH INKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPMGVGGGGVGLHHPHHAQFTSIPMQDPSQMMSRMMNENVNPAAPQS LPGHHDPMLYQTMNYYGNMNAATAAQNTDIMYGSAGPGAAAAQLPFGPKQTIQQLPPGSSYHPTMSNVTQKSNFPSTTHNNSSGLNAQDYHHRSLPVQNNYSESSFQPPVAMINQPQVSYVQSDQTFPTADGFH
Sbjct:    1 MSLANLIEIATNEKQTEDDWTKILDVCEKGTQNPKECLKLILKRLFNINPHIVLRSIILLDACVQNIGEAFTKELSSRYFVNEIKSKSKNIHQKALERLCFMMKKWSRELTGSEYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNRKVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHTINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESKVDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYNMLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPMGVGGGGVGLHHPHHAQFTSIPMQDPSQMMSRMMNENVNPAAPQSALPGHHDPMLYQTMNYYGNMNAATAAQNTDIMYGSAGPGAAAAQLPFGPKQTIQQLPPGSSYHPTMSNVTQKSNFPSTTHNNSSGLNAQDYHHRSLPVQNNYSESSFQPPVAMINQPQVSYVQSDQTFPTADGFH 568
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Planmine SMEST
Match: SMESG000073128.1 (SMESG000073128.1)

HSP 1 Score: 59.3066 bits (142), Expect = 7.077e-9
Identity = 28/80 (35.00%), Postives = 49/80 (61.25%), Query Frame = 1 
Query:  577 NKMPTETVPLKKQLPKV------RALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQ-GMFPAQFVSMDVENE 795
            NK+ T++V L+ Q  K       +A++++E  + +E+ F+ GEII D++  +E WW G N  G+ GMFP+ +V +   N+
Sbjct:  537 NKIDTKSVHLENQDTKTPKTKSAKAVFEYECQDSDEIDFEVGEIITDIEEIDEGWWIGCNKSGKRGMFPSNYVELIATND 616

HSP 2 Score: 50.447 bits (119), Expect = 3.941e-6
Identity = 21/51 (41.18%), Postives = 34/51 (66.67%), Query Frame = 1 
Query:  625 VRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRG-QGMFPAQFV 774
            V A+Y + A +D+E++F+ GE I +V+  +E WW G    G +GMFP+ +V
Sbjct:  645 VVAVYSYHALQDDEISFEEGEHIYNVNQIDEGWWQGETKDGDKGMFPSNYV 695
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Planmine SMEST
Match: SMESG000022674.1 (SMESG000022674.1)

HSP 1 Score: 54.299 bits (129), Expect = 1.284e-7
Identity = 30/81 (37.04%), Postives = 44/81 (54.32%), Query Frame = 1 
Query:  544 NLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDV 786
            +L+ SN +      PT    LK+  P  R L+DFEA  + EL FK GEI+  +   +E+W+ G  +  QG FP  +V + V
Sbjct:  284 SLFKSNTSQ----YPTANGSLKE--PCARGLFDFEAENETELCFKEGEIVKLIQQVDENWFEGEVNGRQGYFPVNYVEIIV 358
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Planmine SMEST
Match: SMESG000022674.1 (SMESG000022674.1)

HSP 1 Score: 54.299 bits (129), Expect = 1.450e-7
Identity = 32/90 (35.56%), Postives = 50/90 (55.56%), Query Frame = 1 
Query:  544 NLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDV--ENEADKF 807
            +L+ SN +    + PT    LK+  P  R L+DFEA  + EL FK GEI+  +   +E+W+ G  +  QG FP  +V + V  +  +DK+
Sbjct:  284 SLFKSNTS----QYPTANGSLKE--PCARGLFDFEAENETELCFKEGEIVKLIQQVDENWFEGEVNGRQGYFPVNYVEIIVPLKRSSDKY 367
[Close]
BLAST of Signal transducing adapter molecule 2 vs. Planmine SMEST
Match: SMESG000022674.1 (SMESG000022674.1)

HSP 1 Score: 53.9138 bits (128), Expect = 2.956e-7
Identity = 32/90 (35.56%), Postives = 49/90 (54.44%), Query Frame = 1 
Query:  544 NLYPSNINHAINKMPTETVPLKKQLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFPAQFVSMDV--ENEADKF 807
            +L+ SN +      PT    LK+  P  R L+DFEA  + EL FK GEI+  +   +E+W+ G  +  QG FP  +V + V  +  +DK+
Sbjct:  284 SLFKSNTSQ----YPTANGSLKE--PCARGLFDFEAENETELCFKEGEIVKLIQQVDENWFEGEVNGRQGYFPVNYVEIIVPLKRSSDKY 367
The following BLAST results are available for this feature:
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
STAM23.469e-7633.81signal transducing adaptor molecule 2 [Source:HGNC... [more]
STAM5.048e-7438.95signal transducing adaptor molecule [Source:HGNC S... [more]
STAM3.914e-2640.48signal transducing adaptor molecule [Source:HGNC S... [more]
GRAP21.084e-942.86GRB2 related adaptor protein 2 [Source:HGNC Symbol... [more]
GRAP21.084e-942.86GRB2 related adaptor protein 2 [Source:HGNC Symbol... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stam-18.219e-4833.33Signal transducing adapter molecule 1 [Source:Uni... [more]
stam-11.213e-4733.33Signal transducing adapter molecule 1 [Source:Uni... [more]
stam-11.213e-4733.33Signal transducing adapter molecule 1 [Source:Uni... [more]
hgrs-11.869e-828.87Hepatocyte Growth factor-Regulated TK Substrate (H... [more]
hgrs-11.869e-828.87Hepatocyte Growth factor-Regulated TK Substrate (H... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Stam4.489e-5934.56gene:FBgn0027363 transcript:FBtr0080143[more]
Abp11.756e-842.59gene:FBgn0036372 transcript:FBtr0075819[more]
drk2.828e-839.39gene:FBgn0004638 transcript:FBtr0087695[more]
drk2.828e-839.39gene:FBgn0004638 transcript:FBtr0087694[more]
drk2.828e-839.39gene:FBgn0004638 transcript:FBtr0087698[more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stam2.559e-7238.32signal transducing adaptor molecule (SH3 domain an... [more]
stam27.103e-6535.57signal transducing adaptor molecule (SH3 domain an... [more]
si:dkey-40c11.29.685e-1250.00si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-3... [more]
si:dkey-40c11.26.027e-1133.88si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-3... [more]
si:dkey-40c11.27.801e-1133.88si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-3... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
adamts89.521e-7438.90ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts81.162e-7338.79ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts82.041e-7338.90ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts83.081e-7338.95ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts81.108e-7238.95ADAM metallopeptidase with thrombospondin type 1 m... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Stam2.164e-7539.47signal transducing adaptor molecule (SH3 domain an... [more]
Stam4.354e-7539.21signal transducing adaptor molecule (SH3 domain an... [more]
Stam29.599e-7437.87signal transducing adaptor molecule (SH3 domain an... [more]
Stam21.009e-5833.69signal transducing adaptor molecule (SH3 domain an... [more]
Stam2.608e-2735.90signal transducing adaptor molecule (SH3 domain an... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O75886|STAM2_HUMAN1.666e-7533.81Signal transducing adapter molecule 2 OS=Homo sapi... [more]
sp|P70297|STAM1_MOUSE3.045e-7439.21Signal transducing adapter molecule 1 OS=Mus muscu... [more]
sp|Q92783|STAM1_HUMAN2.424e-7338.95Signal transducing adapter molecule 1 OS=Homo sapi... [more]
sp|O88811|STAM2_MOUSE6.715e-7337.87Signal transducing adapter molecule 2 OS=Mus muscu... [more]
sp|Q5XHY7|STAM2_RAT3.151e-7237.90Signal transducing adapter molecule 2 OS=Rattus no... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2LPQ72.713e-9141.51Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A4S2LQ722.969e-9141.23Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A5J4NBJ92.309e-9042.23Signal transducing adaptor molecule OS=Paragonimus... [more]
A0A2H1BXJ52.402e-9040.24SH3 domain protein OS=Fasciola hepatica OX=6192 GN... [more]
A0A4E0QY905.868e-9040.19Signal transducing adaptor molecule (Fragment) OS=... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stam9.878e-7339.22signal transducing adaptor molecule [Source:NCBI g... [more]
stam21.458e-7137.93signal transducing adaptor molecule 2 [Source:NCBI... [more]
ENSAMXT00000037557.11.646e-2055.71pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
si:dkey-40c11.21.094e-950.98si:dkey-40c11.2 [Source:ZFIN;Acc:ZDB-GENE-060526-3... [more]
grap2b7.818e-943.86GRB2 related adaptor protein 2b [Source:ZFIN;Acc:Z... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stam2.164e-7339.34signal transducing adaptor molecule (SH3 domain an... [more]
stam2.336e-6435.08signal transducing adaptor molecule (SH3 domain an... [more]
grb2a3.706e-1145.45growth factor receptor-bound protein 2a [Source:ZF... [more]
DBNL2.227e-943.40drebrin like [Source:HGNC Symbol;Acc:HGNC:2696][more]
cttn3.794e-732.84cortactin [Source:ZFIN;Acc:ZDB-GENE-040715-3][more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
HSE11.227e-2025.09Subunit of the endosomal Vps27p-Hse1p complex; com... [more]
ABP11.687e-840.68Actin-binding protein of the cortical actin cytosk... [more]
VPS277.544e-737.78Endosomal protein that forms a complex with Hse1p;... [more]
YSC846.058e-628.21Actin-binding protein; involved in bundling of act... [more]
LSB18.183e-640.00Negative regulator of actin nucleation-promoting f... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO463575.385e-5130.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448641.994e-1228.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO312901.170e-839.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO426895.930e-851.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO380761.749e-740.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stam8.505e-7339.01signal transducing adaptor molecule [Source:NCBI g... [more]
stam23.973e-7038.34signal transducing adaptor molecule 2 [Source:NCBI... [more]
stam21.366e-6939.07signal transducing adaptor molecule 2 [Source:NCBI... [more]
hgs3.654e-926.62hepatocyte growth factor-regulated tyrosine kinase... [more]
grap2a1.425e-833.82growth factor receptor-bound protein 2 [Source:NCB... [more]
back to top
BLAST of Signal transducing adapter molecule 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000033040.10.000e+099.47SMESG000033040.1[more]
SMESG000073128.17.077e-935.00SMESG000073128.1[more]
SMESG000022674.11.284e-737.04SMESG000022674.1[more]
SMESG000022674.11.450e-735.56SMESG000022674.1[more]
SMESG000022674.12.956e-735.56SMESG000022674.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029121 ID=SMED30029121|Name=Signal transducing adapter molecule 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1876bp
TAATAAATATTAATGTCACTAGCTAATTTAATTGAAATAGCTACAAATGA
AAAGCAAACAGAAGATGACTGGACTAAAATACTGGATGTATGTGAAAAAG
GAACGCAAAATCCAAAAGAATGTCTTAAATTAATTCTTAAAAGATTGTTT
AATATTAATCCTCATATTGTGCTAAGAAGTATAATATTACTTGATGCATG
TGTTCAAAACATTGGTGAGCCTTTTACAAAAGAATTAAGTTCTAGGTATT
TTGTTAATGAAATTAAATCCAAATCTAAAAATATCCACCAAAAAGCCCTA
GAAAGACTATGTTTTATGATGAAAAAATGGAGTCGTGAGTTGACAGGAAG
TGAATACGACTGTATTAATGAGTTGAATAAATGGCTTCAAGATACTTATC
CGATAATATACGCTGCAGGAGACGACGAGCTAAATTCACGGAATCCAATT
AAAGGAAATCGTAAAGTTGTTCAAGGTCAAGAAGAAGAAGATCTAGCCAA
AGCGATCGCACTTTCATTGAAAGAATCTGAACAGAAACGGCAGAATCTTT
ATCCATCGAATATAAATCACGCAATCAATAAAATGCCGACAGAAACTGTT
CCTCTGAAGAAACAATTGCCAAAAGTTCGAGCTCTTTATGATTTTGAAGC
TGCTGAAGATAATGAATTGACTTTTAAAGCCGGAGAAATTATAATCGATG
TGGATATGAGTAATGAGCACTGGTGGTATGGAAGCAACCACAGAGGACAG
GGAATGTTTCCCGCCCAATTTGTGTCGATGGATGTAGAAAATGAGGCCGA
TAAATTCGGGGAATCCAATAGAGCAAAAATCGAAAAAGGCTCGGCAGCAA
TCAACCATCAACCTGACAGCTATTCCACTCGACCGATCACGCCGGTTATT
GACGAATCAAAGGTTGACGAGTGTCTTCGAGTAATCGAAGATGCCGATCC
AACCGGTGAATTGCGACCTGACCCGGCGGAACTGTCGAAACTCGAGGCAC
AATGCCGGGTTATGGGCCCGTTAATCGATCAGGAATTGGAAAAGGTCGAT
CGCCATTACAACATGTTGGTGGAATTGAATAGAAATGTCATCGAATCATT
TCAGCTCTACAATGAGCTGATGACCCAAGGTGGCGGCAGTATGAATCGGC
CCGGCAATTACATGTGGCCCCAGCCGATGGGGGTGGGAGGGGGAGGAGTG
GGACTTCACCATCCCCATCACGCGCAATTCACCAGCATTCCGATGCAGGA
TCCTTCTCAAATGATGTCACGAATGATGAATGAGAATGTGAATCCCGCAG
CTCCACAATCGGTTCTCCCTGGGCATCATGATCCCATGCTCTACCAGACA
ATGAATTACTATGGAAACATGAATGCTGCGACTGCTGCTCAAAATACTGA
TATAATGTATGGATCCGCGGGACCGGGCGCAGCGGCGGCACAACTCCCGT
TTGGGCCTAAACAGACCATTCAGCAGTTACCTCCGGGTTCCAGTTATCAC
CCGACAATGTCAAATGTCACACAGAAATCCAATTTCCCCAGCACAACTCA
TAATAACAGTTCTGGTCTCAATGCACAAGATTATCATCACCGATCTCTTC
CTGTGCAAAACAATTACTCAGAGAGTTCTTTCCAACCACCAGTGGCCATG
ATCAACCAACCACAGGTTTCCTATGTTCAGAGTGATCAAACGTTTCCGAC
TGCCGATGGATTTCATTAATTGATTTTTATTCTTTATTTAATTGTCATAG
ATGATAAAAATTAATATTTGCAATTGATATTCACTTGAATAACATTTTGT
GTTTAATAAAATTTATTGATCAGTAACTTTTATTTTGTTATTTTACTCAG
TTGATGGTTTCAATATTATAGAGCGA
back to top

protein sequence of SMED30029121-orf-1

>SMED30029121-orf-1 ID=SMED30029121-orf-1|Name=SMED30029121-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=569bp
MSLANLIEIATNEKQTEDDWTKILDVCEKGTQNPKECLKLILKRLFNINP
HIVLRSIILLDACVQNIGEPFTKELSSRYFVNEIKSKSKNIHQKALERLC
FMMKKWSRELTGSEYDCINELNKWLQDTYPIIYAAGDDELNSRNPIKGNR
KVVQGQEEEDLAKAIALSLKESEQKRQNLYPSNINHAINKMPTETVPLKK
QLPKVRALYDFEAAEDNELTFKAGEIIIDVDMSNEHWWYGSNHRGQGMFP
AQFVSMDVENEADKFGESNRAKIEKGSAAINHQPDSYSTRPITPVIDESK
VDECLRVIEDADPTGELRPDPAELSKLEAQCRVMGPLIDQELEKVDRHYN
MLVELNRNVIESFQLYNELMTQGGGSMNRPGNYMWPQPMGVGGGGVGLHH
PHHAQFTSIPMQDPSQMMSRMMNENVNPAAPQSVLPGHHDPMLYQTMNYY
GNMNAATAAQNTDIMYGSAGPGAAAAQLPFGPKQTIQQLPPGSSYHPTMS
NVTQKSNFPSTTHNNSSGLNAQDYHHRSLPVQNNYSESSFQPPVAMINQP
QVSYVQSDQTFPTADGFH*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
Vocabulary: INTERPRO
TermDefinition
IPR036028SH3-like_dom_sf
IPR001452SH3_domain
IPR002014VHS_dom
IPR003903UIM_dom
IPR008942ENTH_VHS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0006886intracellular protein transport
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 338..358
NoneNo IPR availableGENE3DG3DSA:2.30.30.40coord: 172..258
e-value: 4.5E-20
score: 73.4
NoneNo IPR availablePANTHERPTHR45929FAMILY NOT NAMEDcoord: 5..542
NoneNo IPR availableCDDcd03568VHS_STAMcoord: 6..125
e-value: 5.24919E-36
score: 128.949
IPR001452SH3 domainPRINTSPR00452SH3DOMAINcoord: 245..257
score: 30.17
coord: 217..232
score: 32.51
coord: 234..243
score: 28.25
coord: 203..213
score: 49.59
IPR001452SH3 domainSMARTSM00326SH3_2coord: 203..258
e-value: 1.8E-18
score: 77.4
IPR001452SH3 domainPFAMPF00018SH3_1coord: 206..251
e-value: 7.7E-16
score: 57.4
IPR001452SH3 domainPROSITEPS50002SH3coord: 200..259
score: 23.504
IPR002014VHS domainSMARTSM00288VHS_2coord: 3..129
e-value: 5.8E-13
score: 59.1
IPR002014VHS domainPFAMPF00790VHScoord: 3..125
e-value: 1.1E-19
score: 70.7
IPR002014VHS domainPROSITEPS50179VHScoord: 10..136
score: 22.899
IPR003903Ubiquitin interacting motifSMARTSM00726uimcoord: 156..175
e-value: 0.0025
score: 27.1
IPR003903Ubiquitin interacting motifPFAMPF02809UIMcoord: 156..172
e-value: 1.9E-4
score: 21.1
IPR003903Ubiquitin interacting motifPROSITEPS50330UIMcoord: 156..175
score: 11.197
IPR008942ENTH/VHSGENE3DG3DSA:1.25.40.90coord: 1..136
e-value: 3.0E-24
score: 87.4
IPR008942ENTH/VHSSUPERFAMILYSSF48464ENTH/VHS domaincoord: 3..124
IPR036028SH3-like domain superfamilySUPERFAMILYSSF50044SH3-domaincoord: 174..256