RTR1-type domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30029114 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of RTR1-type domain-containing protein vs. Ensembl Human
Match: RPAP2 (RNA polymerase II associated protein 2 [Source:HGNC Symbol;Acc:HGNC:25791]) HSP 1 Score: 72.7886 bits (177), Expect = 6.186e-13 Identity = 37/135 (27.41%), Postives = 67/135 (49.63%), Query Frame = 3 Query: 81 SIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGE 485 ++R + + + +I+ L + + +F E F+ ++V+ER CGY LC + I P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ + F L ++G GE Sbjct: 47 AVRKKIEFERKALHIVEQLLEENITEEFLMECGRFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITERKSFCSNFCYQASKFFEAQIPKTPVWVREEE-RHPDFQLLKEEQSGHSGE 180
BLAST of RTR1-type domain-containing protein vs. Ensembl Celegans
Match: rpap-2 (Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2 [Source:UniProtKB/Swiss-Prot;Acc:P30641]) HSP 1 Score: 49.2914 bits (116), Expect = 5.386e-6 Identity = 93/401 (23.19%), Postives = 160/401 (39.90%), Query Frame = 3 Query: 165 FRETLNFLCVPELEEIVEERISTNKCGYVLCNNLI-NIHPTAMFSLDISKRKIYNLS-NRKKYCSNWCYGAFKHICDQIPSEPLWKNK--DKITNKVFS------LYPSTETGCGGELYFDED----LYTDENSESDKIAK-KDYHETQQKCNPKKI---IQNINPQQLVNKPNDMTEN-----------PKRQETMKNVINSLDKLAINKKQTLEEVVNKIKTKAVNNQDRKLKIINEHLNDSDMILIPSDE--ESLFVLEKIKF-----LISSWITEETQDFICDS--PNYDLDEDLDNQDGTDDKPINNEECELLPTLDSEDEMTIRRNILIRKAKMACVPILGDFNIEPNNFLKEFEKLIYTCRLTAKNII-FSNKEFKWLII---VFVDLLSSKLG 1241 +E L L +E+VEER +CG+ C I MF +D + KI+ R K+CS CY + Q+ PLW + T KV+ + P E + F ++ L TD IAK +D +++ PK + Q+I P +L + D ++ P + +K + L+ ++ +EV+ K++ K N L ILI + E L +EK K LI SW T ET+ + + P E + D K ++ E+ LP LD + R NI + + + + ++ P ++ T +L ++NI ++ +E ++I + + L+ +LG Sbjct: 34 LQEHLPHLHCLGWDEVVEERYVNKQCGFPSCQKAPPKITRNQMFEIDRKEGKIFEFRKQRAKFCSEMCYQKSSFVRKQLDEHPLWITGLTEARTQKVYEVPDESFVSPIAEKSEPVDSQFKKEPSIWLVTD-----SIIAKVQDMKLSEEAEEPKSLDPEDQDIEPFKLTDDDKDFIKSIKEFRNSNFGPPSTSKLLKTAPKPV--LSAKDRKKEDEVLAKLRAKYGNKN---------ALQKKPPILIEAQEIHSKLKTMEKAKEAWLVDLIKSWFTPETRKLVREGARPTGGAAEQI-LMDFLSGKKVDAEKLVNLPNLDKYNVKEKRLNIFLHSIRNHWMDLEARLHLTPTR-RDILSRVASTFQLDSENITGWTKREINSIVIALFIVICLVDVELG 416
BLAST of RTR1-type domain-containing protein vs. Ensembl Celegans
Match: rpap-2 (Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2 [Source:UniProtKB/Swiss-Prot;Acc:P30641]) HSP 1 Score: 49.2914 bits (116), Expect = 5.386e-6 Identity = 93/401 (23.19%), Postives = 160/401 (39.90%), Query Frame = 3 Query: 165 FRETLNFLCVPELEEIVEERISTNKCGYVLCNNLI-NIHPTAMFSLDISKRKIYNLS-NRKKYCSNWCYGAFKHICDQIPSEPLWKNK--DKITNKVFS------LYPSTETGCGGELYFDED----LYTDENSESDKIAK-KDYHETQQKCNPKKI---IQNINPQQLVNKPNDMTEN-----------PKRQETMKNVINSLDKLAINKKQTLEEVVNKIKTKAVNNQDRKLKIINEHLNDSDMILIPSDE--ESLFVLEKIKF-----LISSWITEETQDFICDS--PNYDLDEDLDNQDGTDDKPINNEECELLPTLDSEDEMTIRRNILIRKAKMACVPILGDFNIEPNNFLKEFEKLIYTCRLTAKNII-FSNKEFKWLII---VFVDLLSSKLG 1241 +E L L +E+VEER +CG+ C I MF +D + KI+ R K+CS CY + Q+ PLW + T KV+ + P E + F ++ L TD IAK +D +++ PK + Q+I P +L + D ++ P + +K + L+ ++ +EV+ K++ K N L ILI + E L +EK K LI SW T ET+ + + P E + D K ++ E+ LP LD + R NI + + + + ++ P ++ T +L ++NI ++ +E ++I + + L+ +LG Sbjct: 34 LQEHLPHLHCLGWDEVVEERYVNKQCGFPSCQKAPPKITRNQMFEIDRKEGKIFEFRKQRAKFCSEMCYQKSSFVRKQLDEHPLWITGLTEARTQKVYEVPDESFVSPIAEKSEPVDSQFKKEPSIWLVTD-----SIIAKVQDMKLSEEAEEPKSLDPEDQDIEPFKLTDDDKDFIKSIKEFRNSNFGPPSTSKLLKTAPKPV--LSAKDRKKEDEVLAKLRAKYGNKN---------ALQKKPPILIEAQEIHSKLKTMEKAKEAWLVDLIKSWFTPETRKLVREGARPTGGAAEQI-LMDFLSGKKVDAEKLVNLPNLDKYNVKEKRLNIFLHSIRNHWMDLEARLHLTPTR-RDILSRVASTFQLDSENITGWTKREINSIVIALFIVICLVDVELG 416
BLAST of RTR1-type domain-containing protein vs. Ensembl Fly
Match: CG34183 (gene:FBgn0085212 transcript:FBtr0112376) HSP 1 Score: 80.1073 bits (196), Expect = 1.460e-17 Identity = 40/132 (30.30%), Postives = 72/132 (54.55%), Query Frame = 3 Query: 63 NENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYP 458 + I ++ +++ R + I++ L + + F L + P +IV+ER CGY LC+ ++ P +S+ SK K+Y+++ RKK+CS +C+ A ++I Q+P+ PLW +D+ T F L P Sbjct: 10 RQQLIAAVVKKRAAIARAHEIVVRLLEPGIPEPEFLSLLCEIGPPNYSDIVDEREINKLCGYPLCSTVLENVPKQKYSISASKNKVYDITERKKFCSGYCFKASEYIKSQVPTSPLWL-RDRETRPSFQLLP 140
BLAST of RTR1-type domain-containing protein vs. Ensembl Zebrafish
Match: rpap2 (RNA polymerase II associated protein 2 [Source:NCBI gene;Acc:554138]) HSP 1 Score: 60.8474 bits (146), Expect = 2.401e-9 Identity = 31/91 (34.07%), Postives = 47/91 (51.65%), Query Frame = 3 Query: 213 VEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGE 485 VEER CGY +C N + PT + + K+Y+++ RK +CSN+CY A K QI PLW K++ ++ L + G G+ Sbjct: 85 VEERSIAKLCGYPMCPNKLTNVPTQQYKISTKTNKVYDITERKCFCSNFCYKASKSFELQISKIPLWLRKEESPPEI-KLMKQGDGGSSGQ 174
BLAST of RTR1-type domain-containing protein vs. Ensembl Xenopus
Match: RPAP2 (RNA polymerase II associated protein 2 [Source:NCBI gene;Acc:100491941]) HSP 1 Score: 60.4622 bits (145), Expect = 4.500e-9 Identity = 25/75 (33.33%), Postives = 41/75 (54.67%), Query Frame = 3 Query: 189 CVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLW 413 C ++ VEER CGY +C N + P + + K+Y+++ RK +CSN+C+ A K+ Q+P P+W Sbjct: 72 CPGPYKDTVEERTIIQLCGYPVCQNRLENVPKQKYKISTKTNKVYDITERKCFCSNFCFRASKYYEAQLPKTPVW 146
BLAST of RTR1-type domain-containing protein vs. Ensembl Mouse
Match: Rpap2 (RNA polymerase II associated protein 2 [Source:MGI Symbol;Acc:MGI:2141142]) HSP 1 Score: 70.0922 bits (170), Expect = 2.778e-12 Identity = 33/110 (30.00%), Postives = 56/110 (50.91%), Query Frame = 3 Query: 159 KFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGEL 488 +F +E F+ ++V+ER CGY LC + + P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ F L ++G GE+ Sbjct: 73 EFLKECGMFITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYRASKFFETQIPKTPVWVREEERPPD-FQLLKKGQSGSSGEV 181
BLAST of RTR1-type domain-containing protein vs. Ensembl Mouse
Match: Rpap2 (RNA polymerase II associated protein 2 [Source:MGI Symbol;Acc:MGI:2141142]) HSP 1 Score: 69.707 bits (169), Expect = 3.207e-12 Identity = 33/110 (30.00%), Postives = 56/110 (50.91%), Query Frame = 3 Query: 159 KFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGEL 488 +F +E F+ ++V+ER CGY LC + + P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ F L ++G GE+ Sbjct: 73 EFLKECGMFITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYRASKFFETQIPKTPVWVREEERPPD-FQLLKKGQSGSSGEV 181
BLAST of RTR1-type domain-containing protein vs. Ensembl Mouse
Match: Rpap2 (RNA polymerase II associated protein 2 [Source:MGI Symbol;Acc:MGI:2141142]) HSP 1 Score: 70.0922 bits (170), Expect = 3.287e-12 Identity = 33/110 (30.00%), Postives = 56/110 (50.91%), Query Frame = 3 Query: 159 KFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGEL 488 +F +E F+ ++V+ER CGY LC + + P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ F L ++G GE+ Sbjct: 73 EFLKECGMFITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYRASKFFETQIPKTPVWVREEERPPD-FQLLKKGQSGSSGEV 181
BLAST of RTR1-type domain-containing protein vs. Ensembl Mouse
Match: Rpap2 (RNA polymerase II associated protein 2 [Source:MGI Symbol;Acc:MGI:2141142]) HSP 1 Score: 61.2326 bits (147), Expect = 1.489e-11 Identity = 26/77 (33.77%), Postives = 41/77 (53.25%), Query Frame = 3 Query: 183 FLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLW 413 F+ ++V+ER CGY LC + + P + + K+Y+++ RK +CSN+CY A K QIP P+W Sbjct: 2 FITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYRASKFFETQIPKTPVW 78
BLAST of RTR1-type domain-containing protein vs. Ensembl Mouse
Match: Rpap2 (RNA polymerase II associated protein 2 [Source:MGI Symbol;Acc:MGI:2141142]) HSP 1 Score: 66.6254 bits (161), Expect = 2.848e-11 Identity = 31/102 (30.39%), Postives = 52/102 (50.98%), Query Frame = 3 Query: 183 FLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGEL 488 F+ ++V+ER CGY LC + + P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ F L ++G GE+ Sbjct: 2 FITPAHYSDVVDERSIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYRASKFFETQIPKTPVWVREEERPPD-FQLLKKGQSGSSGEV 102
BLAST of RTR1-type domain-containing protein vs. UniProt/SwissProt
Match: sp|A8DYY5|RPAP2_DROME (Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Drosophila melanogaster OX=7227 GN=CG34183 PE=2 SV=1) HSP 1 Score: 80.1073 bits (196), Expect = 1.463e-16 Identity = 40/132 (30.30%), Postives = 72/132 (54.55%), Query Frame = 3 Query: 63 NENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYP 458 + I ++ +++ R + I++ L + + F L + P +IV+ER CGY LC+ ++ P +S+ SK K+Y+++ RKK+CS +C+ A ++I Q+P+ PLW +D+ T F L P Sbjct: 10 RQQLIAAVVKKRAAIARAHEIVVRLLEPGIPEPEFLSLLCEIGPPNYSDIVDEREINKLCGYPLCSTVLENVPKQKYSISASKNKVYDITERKKFCSGYCFKASEYIKSQVPTSPLWL-RDRETRPSFQLLP 140
BLAST of RTR1-type domain-containing protein vs. UniProt/SwissProt
Match: sp|F6RRD7|RPAP2_BOVIN (Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Bos taurus OX=9913 GN=RPAP2 PE=2 SV=1) HSP 1 Score: 76.6406 bits (187), Expect = 1.952e-13 Identity = 39/135 (28.89%), Postives = 69/135 (51.11%), Query Frame = 3 Query: 81 SIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGE 485 ++R + + + +I+ L + + +F RE F+ ++V+ER CGY LC N + I P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ + F L ++G GE Sbjct: 47 AVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEE-RHPDFQLLQDGQSGPSGE 180
BLAST of RTR1-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5I0E6|RPAP2_RAT (RNA polymerase II subunit B1 CTD phosphatase Rpap2 OS=Rattus norvegicus OX=10116 GN=Rpap2 PE=1 SV=1) HSP 1 Score: 75.8702 bits (185), Expect = 3.403e-13 Identity = 40/141 (28.37%), Postives = 68/141 (48.23%), Query Frame = 3 Query: 159 KFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGELYFDEDLYTDENSESDKIAKKDYHETQQKCNP 581 +F +E F+ ++V+ER CGY LC + + P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ + F L ++GC GE+ + D + +D A Y +C P Sbjct: 73 EFLKECGMFITPAHYSDVVDERAIIKLCGYPLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYKASKFFEAQIPKTPVWVREEERPPE-FQLLKKGQSGCSGEVV---QFFRDAVTAADVDA---YGAFDAQCEP 206
BLAST of RTR1-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RA37|RPAP2_PONAB (Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Pongo abelii OX=9601 GN=RPAP2 PE=2 SV=1) HSP 1 Score: 72.7886 bits (177), Expect = 2.721e-12 Identity = 37/135 (27.41%), Postives = 67/135 (49.63%), Query Frame = 3 Query: 81 SIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGE 485 ++R + + + +I+ L + + +F E F+ ++V+ER CGY LC + I P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ + F L ++G GE Sbjct: 47 AVRKKIEFERKALHIVEQLLEENITEEFLMECGKFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITERKSFCSNFCYQASKFFEAQIPKTPVWVREEE-RHPDFQLLKEQQSGHSGE 180
BLAST of RTR1-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8IXW5|RPAP2_HUMAN (Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Homo sapiens OX=9606 GN=RPAP2 PE=1 SV=1) HSP 1 Score: 72.7886 bits (177), Expect = 2.971e-12 Identity = 37/135 (27.41%), Postives = 67/135 (49.63%), Query Frame = 3 Query: 81 SIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGE 485 ++R + + + +I+ L + + +F E F+ ++V+ER CGY LC + I P + + K+Y+++ RK +CSN+CY A K QIP P+W +++ + F L ++G GE Sbjct: 47 AVRKKIEFERKALHIVEQLLEENITEEFLMECGRFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITERKSFCSNFCYQASKFFEAQIPKTPVWVREEE-RHPDFQLLKEEQSGHSGE 180
BLAST of RTR1-type domain-containing protein vs. TrEMBL
Match: A0A1Y1MXG2 (RTR1-type domain-containing protein OS=Photinus pyralis OX=7054 GN=PPYR_08593 PE=4 SV=1) HSP 1 Score: 94.7449 bits (234), Expect = 5.904e-17 Identity = 97/420 (23.10%), Postives = 176/420 (41.90%), Query Frame = 3 Query: 66 ENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGG-------------ELYFDEDLYTDENS-----ESDKIAK----KDYHETQQKCNPKKIIQNINPQQLVNKPNDMTENPKRQETMKNVI---NSLDKLA-INKKQTLEEVVNKIKTKAVNNQDRKLKIINEHLNDSDMILIPSDEESLFVLEKIKFLISSWITEETQDFICDSPNYDLDEDLDNQDGTDDKPINNEECELLPTLDSEDEMTIRRNILIRKAKMACVPILGDFNIEPNNFLKEFEKLIYTCRLTAKNIIFSNKEFKWLIIVFVDLLSSKLGKV 1247 +N ++ +K + R +L L + V + F +NFL +++VEER N CGY LCNN I FS+D K+Y+++NRKK+CSN+CY A HI QI PLW ++ ++L P T+ G G E+ FD E S +D+ AK K H ++ P + + ++ +P T R T+K I SLD + ++ + E K+ +++ + +N+ +++ ++ F E S + ++++D ++ E D D + E P L +R+ I + A ++ +E L + E L+ T L A +++F E+ + ++ + +LS + ++ Sbjct: 27 DNITATLLKKKECESRAMKLLEFLIEGKVRSEVFLRCINFLNRSYYQDVVEERSIMNLCGYCLCNNTIPKMTAKRFSIDSKNNKVYDITNRKKHCSNFCYKASLHIEKQIDDSPLWLRSFEVL-PTYTLLPVTDKGLPGDDVNSDTNILDKEEVQFDSSYSFAEASLHEMTNADEKAKQEDNKKAHTPTKEPPPHSQTSSDYARHVLKQPQPKTTKRNRSATLKKYILEWLSLDTYVFLFGRELVRERALKLNLPIPSSEVLTQRKLNQLCRKLELVDCRDKDKMTFHQELKPVPTYSQLKKDSKDISVKVRSFYSGETYDVSKSEDGDSLTMGES---PNL-------VRQEIFLTNINTAIKTLVEHLGVESAVTLTKIELLVRTFSLHAYSVVFQPVEWSLIALILIKMLSIRDAQI 435
BLAST of RTR1-type domain-containing protein vs. TrEMBL
Match: A0A158P179 (RTR1-type domain-containing protein OS=Atta cephalotes OX=12957 GN=105626855 PE=4 SV=1) HSP 1 Score: 92.0485 bits (227), Expect = 6.443e-16 Identity = 46/144 (31.94%), Postives = 78/144 (54.17%), Query Frame = 3 Query: 57 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLW-KNKDKITNKVFSLYPSTETGCGGE 485 M+ E ++I +K D + I++ L + +VD + + L F+ +E+++EER CGYVLC+N + + + + K K+Y++S RK +CS+ CYGA + +Q+ PLW + K+ I VF + P T GE Sbjct: 1 MSKEQMQLAIIKKKQCDAKALAIVMQLLESHVDSDWLLQNLGFISKNHMEDVIEERAIVKLCGYVLCSNQLTVIIRQQYHISTRKNKVYDVSKRKNFCSSLCYGAANFLLEQMLESPLWLREKEDIP--VFQILPVNSTSTCGE 142
BLAST of RTR1-type domain-containing protein vs. TrEMBL
Match: A0A151IP99 (Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Cyphomyrmex costatus OX=456900 GN=ALC62_01381 PE=4 SV=1) HSP 1 Score: 90.5077 bits (223), Expect = 1.944e-15 Identity = 51/170 (30.00%), Postives = 92/170 (54.12%), Query Frame = 3 Query: 57 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLW-KNKDKITNKVFSLYP-STETGCGGE-----LYFDEDLYTDENSESDKIAK 545 M+ E ++I +K D + I++ L + +V+ + + L F+ +E+++EER+ CGYVLC+N + + + + K K+Y++S R+ +CS+ CYGA + +Q+ PLW + K+ I VF + P +++ CG E + F E+ D N +S K K Sbjct: 17 MSKEQMQLAIIKKKQCDAKALAIVMQLLEPHVNPDWLLQNLGFMSKNHMEDVIEERVIVKLCGYVLCSNQLTVVIRQQYHISTRKNKVYDVSKRRNFCSSLCYGATNFLLEQMLESPLWLREKEDIP--VFQILPLNSKPTCGEEIDVAGINFPENKNVDNNDDSKKSTK 184
BLAST of RTR1-type domain-containing protein vs. TrEMBL
Match: A0A151WWM2 (Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (Fragment) OS=Trachymyrmex zeteki OX=64791 GN=ALC60_08772 PE=4 SV=1) HSP 1 Score: 90.5077 bits (223), Expect = 2.277e-15 Identity = 44/146 (30.14%), Postives = 83/146 (56.85%), Query Frame = 3 Query: 57 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLW-KNKDKITNKVFSLYP-STETGCGGEL 488 M+ E ++I +K D + I++ L + +VD + + + F+ +E+++EER CGYVLC+N + + + + K K+Y++S R+ +CS+ CYGA + +Q+ PLW + K+ I VF + P ++++ CG E+ Sbjct: 24 MSKEQMQLAIIKKKQCDAKALAIVMQLLESHVDSDWLLQNVRFISKSHMEDVIEERAIVKLCGYVLCSNQLTVIIRQQYHISTRKNKVYDVSKRRNFCSSLCYGAANFLLEQMLESPLWLREKEDIP--VFQILPLNSKSTCGEEI 167
BLAST of RTR1-type domain-containing protein vs. TrEMBL
Match: A0A4V3SCP6 (Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Temnothorax longispinosus OX=300112 GN=DBV15_09847 PE=4 SV=1) HSP 1 Score: 90.1225 bits (222), Expect = 2.771e-15 Identity = 45/146 (30.82%), Postives = 80/146 (54.79%), Query Frame = 3 Query: 57 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYP--STETGCGGEL 488 M+ +++ +K D + I++ L + +VD + + L + +E+++EER CGYVLC+N + + + + SK K+Y++S RK +CS+ CYGA ++ +Q+ PLW ++K VF + P S T CG E+ Sbjct: 19 MSXAQLQLAVIKKKQCDAKALAIVVQLLEPHVDPDWLLQNLGLISKSHMEDVIEERAIVKLCGYVLCSNQLTVIIRQKYHISTSKNKVYDVSKRKNFCSSSCYGAANYLLEQMLESPLWM-REKEDIPVFQILPLSSKSTQCGDEI 163
BLAST of RTR1-type domain-containing protein vs. Ensembl Nematostella
Match: EDO44305 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWF1]) HSP 1 Score: 60.077 bits (144), Expect = 1.300e-9 Identity = 37/126 (29.37%), Postives = 64/126 (50.79%), Query Frame = 3 Query: 81 SIRNRKSHDVRFYNILIALS-DVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLC-NNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSL 452 SI+ + + + R + I+ L + + ++F E N++ ++V ER CGY LC +L NI P F + ++Y+++ RK +CSN CY A K Q+ P+W + + K F+L Sbjct: 42 SIKAQVAAEQRAHQIVEKLVLEEFATPEYFLEIGNYITHRHYSDVVTERFIIKICGYPLCPKSLTNI-PKQTFKISTRTNRVYDITERKCFCSNICYKASKFYESQLDESPIW-TRSRAGLKEFTL 165
BLAST of RTR1-type domain-containing protein vs. Ensembl Medaka
Match: rpap2 (RNA polymerase II associated protein 2 [Source:NCBI gene;Acc:101160099]) HSP 1 Score: 67.0106 bits (162), Expect = 5.106e-12 Identity = 34/114 (29.82%), Postives = 55/114 (48.25%), Query Frame = 3 Query: 81 SIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNK 422 ++R + + R ++ L + V F E+ F+ + VEER CGY C + P+ F + ++Y+++ RK++CSN+CY A K QIP PLW K Sbjct: 20 ALREQLELERRALEVVEQLLESSVAEDFLLESAKFITPANYRDAVEERSILKLCGYPTCPKQLGKIPSQQFKISTKTNRVYDITERKRFCSNFCYKASKEFELQIPKTPLWLRK 133
BLAST of RTR1-type domain-containing protein vs. Planmine SMEST
Match: SMESG000077225.1 (SMESG000077225.1) HSP 1 Score: 888.641 bits (2295), Expect = 0.000e+0 Identity = 437/446 (97.98%), Postives = 442/446 (99.10%), Query Frame = 3 Query: 57 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGELYFDEDLYTDENSESDKIAKKDYHETQQKCNPKKIIQNINPQQLVNKPNDMTENPKRQETMKNVINSLDKLAINKKQTLEEVVNKIKTKAVNNQDRKLKIINEHLNDSDMILIPSDEESLFVLEKIKFLISSWITEETQDFICDSPNYDLDEDLDNQDGTDDKPINNEECELLPTLDSEDEMTIRRNILIRKAKMACVPILGDFNIEPNNFLKEFEKLIYTCRLTAKNIIFSNKEFKWLIIVFVDLLSSKLGKVDDDKKASVLKKHGITQSHLYEKVLEDIYSYIDQPVNISLSPQGDSIECK 1394 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIP EPLWKNKDKITNKVFSLYPSTE GCGGELYFDEDLYTDENSESDKIAK DYHETQQKCNPKKIIQNI+PQQL NKPNDMTENPKRQETMKNVINSLDKLAINKK+TLEEVVNKIKTKAVNNQ+RKLKIINEHLNDSDMILIPSDEESLFVLEKIKFLISSWITEETQDFICDSPNYDLDEDLDNQDGTDDKPINNEECELLPTLDSEDEMTIRRNILI+KAKMACVPILGDFNIEPNNFLKEFEKLIYTCRLTAKNIIFSNKEFKWLIIVFVDLLSSKLGKVDDD+KASVLKKHGITQSHLYEKVLEDIYSYIDQPVNISLSPQGDSIECK Sbjct: 1 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPWEPLWKNKDKITNKVFSLYPSTENGCGGELYFDEDLYTDENSESDKIAKNDYHETQQKCNPKKIIQNISPQQLANKPNDMTENPKRQETMKNVINSLDKLAINKKKTLEEVVNKIKTKAVNNQNRKLKIINEHLNDSDMILIPSDEESLFVLEKIKFLISSWITEETQDFICDSPNYDLDEDLDNQDGTDDKPINNEECELLPTLDSEDEMTIRRNILIKKAKMACVPILGDFNIEPNNFLKEFEKLIYTCRLTAKNIIFSNKEFKWLIIVFVDLLSSKLGKVDDDRKASVLKKHGITQSHLYEKVLEDIYSYIDQPVNISLSPQGDSIECK 446
BLAST of RTR1-type domain-containing protein vs. Planmine SMEST
Match: SMESG000077222.1 (SMESG000077222.1) HSP 1 Score: 368.237 bits (944), Expect = 1.250e-123 Identity = 215/437 (49.20%), Postives = 282/437 (64.53%), Query Frame = 3 Query: 57 MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEEIVEERISTNKCGYVLCNNLINIHPTAMFSLDISKRKIYNLSNRKKYCSNWCYGAFKHICDQIPSEPLWKNKDKITNKVFSLYPSTETGCGGELYFDE--DLYTDENSESDKIAKKDYHETQQKCNPKKIIQNINPQQLVNKPNDMTENPKRQETMKNVINSLDKLAINKK--QTLEEVVNKIKTKAVNNQDRKLKIINEHLNDSDMILIPSDEESLFVLEKIKFLISSWITEETQDFICDSPNYDLDEDLDNQDGTDDKPINNEECELLPTLDSEDEMTIRRNILIRKAKMACVPILGDFNIEPNNFLKEFEKLIYTCRLTAKNIIFSNKEFKWLIIVFVDLLSSKLGKVDDDKKASVLKKHGITQSHLYEKVLEDIYSYIDQPVN 1355 M EN + R++K H++RF+ LI+LS+ V+WKFFRETL ++CV ELEEI EE+ NKCGYVLCNN I + P A++SL+ SK +I+ +S RKKYCS+WCYGA+KHI Q+PSEPLWKNK+K +K+F+LYP GC GEL+ DE D DE + S+K +Y N + QN +P+ V K T+ P R++T K +N + N K ++LEEV+NKI+ NN K+ + +++N+ M LI SDE+ L LEK+K + W+T T F +S N D E Q+ TD++ EE LPTLDS D+M IRRNILI KA AC I+ DF I + FLKEFEK + CRLTAKNI FSN E KWL+IV +DLL K KVD DKKA +LKKHG++Q LYEKVLE+I S +N Sbjct: 1 MVWENNSLFTRDQKCHELRFFKFLISLSEEDVEWKFFRETLRYICVAELEEITEEKNCKNKCGYVLCNNSIIVPPNAIYSLNTSKNQIFKISKRKKYCSDWCYGAYKHISSQVPSEPLWKNKEKFIDKIFTLYPKCAVGCPGELHSDEEIDATEDEKTISNKEISTNYT------NVIRNYQNKSPEMNVLK----TQMPTRKQTTK--VNECINIQENPKKVKSLEEVLNKIRKNTTNNPKCKMINLEQNMNNCRMSLITSDEKILKHLEKVKSNVCDWMTWNTPKFPWNSSNCDFAE---YQENTDERC---EEIFKLPTLDSADQMEIRRNILISKALTACNLIIEDFLITTDIFLKEFEKFLCNCRLTAKNISFSNNEIKWLMIVIIDLLPPKFEKVDYDKKAFILKKHGLSQCQLYEKVLEEIKSCFYHSIN 419 The following BLAST results are available for this feature:
BLAST of RTR1-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 1
BLAST of RTR1-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of RTR1-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of RTR1-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of RTR1-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of RTR1-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of RTR1-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of RTR1-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of RTR1-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of RTR1-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of RTR1-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of RTR1-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of RTR1-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of RTR1-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30029114 ID=SMED30029114|Name=RTR1-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1491bpback to top protein sequence of SMED30029114-orf-1 >SMED30029114-orf-1 ID=SMED30029114-orf-1|Name=SMED30029114-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=447bp MANENCIISIRNRKSHDVRFYNILIALSDVYVDWKFFRETLNFLCVPELEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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