Protocadherin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30029104 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 254.988 bits (650), Expect = 8.869e-70 Identity = 229/787 (29.10%), Postives = 373/787 (47.40%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITR-IINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L + F N T++EE N IGN+ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++++++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F +F V EN+ +G +T TD D G+NS V TL+ E S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 41 IFAVLLVCV--VFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 801
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 254.603 bits (649), Expect = 9.254e-70 Identity = 229/787 (29.10%), Postives = 373/787 (47.40%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITR-IINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L + F N T++EE N IGN+ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++++++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F +F V EN+ +G +T TD D G+NS V TL+ E S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 30 IFAVLLVCV--VFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 790
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 254.603 bits (649), Expect = 9.254e-70 Identity = 229/787 (29.10%), Postives = 373/787 (47.40%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITR-IINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L + F N T++EE N IGN+ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++++++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F +F V EN+ +G +T TD D G+NS V TL+ E S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 30 IFAVLLVCV--VFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 790
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 254.603 bits (649), Expect = 1.008e-69 Identity = 229/787 (29.10%), Postives = 373/787 (47.40%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITR-IINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L + F N T++EE N IGN+ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++++++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F +F V EN+ +G +T TD D G+NS V TL+ E S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 41 IFAVLLVCV--VFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 801
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 256.529 bits (654), Expect = 1.066e-69 Identity = 228/788 (28.93%), Postives = 375/788 (47.59%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L + F N T++EE N IGN+ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++++++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F +F V EN+ +G +T TD D G+NS V +L + F++ S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 41 IFAVLLVCV--VFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-------DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 801
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 167.162 bits (422), Expect = 1.786e-41 Identity = 187/698 (26.79%), Postives = 314/698 (44.99%), Query Frame = 2
Query: 323 NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDF-SAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD-----RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMS--GWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTI-EDENDNAPIFGVIPEFTVK--ENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSAT 2359
+G++ L K +D E L + +I KV +R D S TV + + D+ DN+P+F +RE P+ ++ S F RD S EN Y L + + K L + + ++ + LD ET RL + A D R+S E I V D NDN P+F + Y V+ILEN +++ TV A D+D G G V Y++ + + I I+ ++GE+ L R+ A + V + D P VP+ I V DIN++ P + ++ + + + EN G + + D D G N + + E DF + E+ + + + D E+ S + D G+P +T ++ V + D+N+ +P F + Y V++ E ++++ L A D D I Y ++E + F I + G I + + L R+ + V + D + +V + D+ ++AP F P F+VK E+ + L A D D+G+N+++ + + + + F + G I LDRE ++++ V D P+ TST + V + D NDN PQ+ + + I+ I + V A D D G NG + Y ++ + +F LD SG +R+ +LD +Q I L I A D T
Sbjct: 219 SGEIRLAKSMDREVL--DKHI----------LKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIG--TTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGV-IQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVE--ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSG---IGGLTIDYSTGEVTLRERIDAKNSPITA---VIRAKDGAQPALSSTVPLTINVIDINDHAPTL--IAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGII--KYSMEGSEDFII---DEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVRV-----EISATDQGGLQGRCVVNVFIDDVNSAPYFNDHP-FSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI--------DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSS---SYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGT 869 HSP 2 Score: 149.058 bits (375), Expect = 6.076e-36 Identity = 166/633 (26.22%), Postives = 280/633 (44.23%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC-----TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVL-VHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDS---GEIRLVKELDFD 2320
V + + D+NDN P+F++ +T+ E++ + ++ A D DF ++ Y + SS L T + + L+ +D K +T +D + L I+V D ND+ P +++ EN G V V A D+DSG G++ Y+++ D F I+ +SG I+ + L Y+ V A+D P + + ++DIN+ P N V + E G+ +IT+K DND + K+ ++ + F +L + L+ + +V+ I TD G R V+ V I D+N +P F + V + E++ V+ L A D D A I YS+D FF+ID SG I + LDRE T A D P +T+I V ++D NDN+P F T+ E++ +++A DAD G N V++ L ++ + +Q G + LDRE F L + RD+G ++ ++ +T+ + D NDN P + ++ + I V T+ A D D G+N I +RI + +F ++ED+ G +R++ +FD
Sbjct: 361 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVH-YSMASSSGIGGL-TIDYSTGEVTLRERID---AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED------FIIDEDSGLIKTTKLLDRETTARYSLKVTARD--MGTPSLNTSTTIAVVLKDINDNAPTFDKKEYN--VTISEEMPRGSQIITLKAVDND--EDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVR-VEISATDQGG---LQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS--QFFRIDPSSGDISVSSD-LDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNES-SSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTF---EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFG---GADAKLFDIEEDAEQNGVVRILTRAEFD 961 HSP 3 Score: 146.362 bits (368), Expect = 4.172e-35 Identity = 173/660 (26.21%), Postives = 288/660 (43.64%), Query Frame = 2
Query: 209 EEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQIN--DLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPND-----LDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDIN-----NYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKA----FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE----GFIETL--QSLDRET-FESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKP 2098
E+F N G + Y++ L + + G+VTL++RID +NS I + D S TV L IN D+ND+ P ++ ITL E++ + + A D D S N I Y +E S + F +D + +L LD ET +Y L + A D + T + + ++D NDN P F K Y V+I E GS ++T+ A D D + Y I+ + LD+ I S SGE++ R+ + V +D Q V V + ++D+N N +P V++ E++ G +IT+K D+D G N+++ + + Q + + ++ D E S + +D SPP +T + V + D+N+ SP+F Y ++ E+ T LQ++A D D + + Y L+E + F++D SG ++ + LDRE IV FA D +A ++I +T+ D NDNAP F + + + EN +G + A DAD+G+N+ + F + K+F + ++ G + L D E + E+ G+ ++++ V + V D NDNKP
Sbjct: 402 EDFGTN---GKVHYSMASSSGIGGLTIDYST--------GEVTLRERIDA----KNSPI---------TAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDED-SGPNGIIKYSMEGSED-FIIDEDSGLIKTTKL---LDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQK--ITYRIEEADREVFSILDIGDQGAILSVSGELK---------RQDHKVRVEISATDQGGLQGRCV-VNVFIDDVNSAPYFNDHPF--------SVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS-----QFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSK-LDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGAD-----AKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQA-SSGQ--LSSTVPVRIHVSDVNDNKP 998 HSP 4 Score: 116.316 bits (290), Expect = 7.244e-26 Identity = 121/493 (24.54%), Postives = 220/493 (44.62%), Query Frame = 2
Query: 818 FTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAP-IFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT--RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSL 2272
F + Y + E+T +++ +V A S L Y++ AP D F +++ SGEIRL + + + V A + + V + V D+ + P+ + E+RE+ G ++++ D D G N ++ L + + + K + A+ D E+ + + +D G+P + + V + + D+N+ +P F Y V++ EN + + ATD D + YS+ G ID+ +G + + + + T V A D ++T + + + D ND+AP + T++EN+ +GR+ A D D G N +++ + E + F + ++ G I+T + LDRET Y+L+V RD G + TST + V + D NDN P + EYN+T + + ++T++A D D E+ +I YRI + + VFS+
Sbjct: 165 FQQEKYVKELPEDTPIETIIASVKASHASSQPL---YYSMVAPQDSRSQNLFTLDTMSGEIRLAKSMDREVLDKHILKVTAYER-VDPTISASTTVVVHVLDVQDNSPIFE--KDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVIQTAA--PLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIR--AKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM--------EGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFD-----KKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIE----EADREVFSI 628 HSP 5 Score: 100.138 bits (248), Expect = 6.285e-21 Identity = 106/405 (26.17%), Postives = 185/405 (45.68%), Query Frame = 2
Query: 410 IQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS-----CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVR-----SFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDE 1588
++ ++ D+ VN+ I+D+N + P F+ ++ + E P+ Y + A D D RI Y + DSS F +D S + + S+LD E R + + + A D S T E+I+D D NDN P FT + Y +I E+ G+ + V+A D D G G+V Y ++ + IQ F ++ SG +R+ +L Q + + A+D P + +T+ D+N+ P LS + + + EN+ G+ + TI D D G N+ ++ + D +L +E+ VR FD+E+ K SG S+ V +H++D+N+ P K + ++ +N ++ + A D D A++ Y L+E
Sbjct: 651 VRVEISATDQGGLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARI-VYSI-DSSQFFRIDPSSG---DISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILD--DINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDR--GTPSLSAASEITLTLSDVNDNAPTFEQLSYD--LYIAENSPVGSTVGTIVARDADEGDNADIS--FRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQ--LSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPDQNATLEYFLEE 1039
BLAST of Protocadherin vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 149.443 bits (376), Expect = 5.557e-36 Identity = 169/662 (25.53%), Postives = 289/662 (43.66%), Query Frame = 2
Query: 455 SLTVNLQI-NDLNDNT---PLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELI-IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE-KVPVEITVEDINNYYPVIAILSTNERVEVR--ENTLPGNLITIKVSDNDIGMNSKVNCELQT-ESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCT-DSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL---DFDQIELTIIASDSATKPKMVMLKL 2386
+L+ +LQ+ DL D P F + + E P+ + A + RI Y L++ +DT ++ ++ D+E +K Y+ T+ A + +S T LI I ++D NDN PIF N Y +++ E ++ V+A D DSG G V Y+I L +F IN +GE+ ++ LA + FH+V D E + ITV D + P + + E+R E+ LPG ++ +G SKV + + + +F + + +Y R D + +I+ T SG +S V++ I D N+ P+F + E+S+RE+ + + A+D+D +RYS+ + +ID +G + T ++ LD E A D + P ++ + + + D NDNAP F V EN ++G++ A D D N Q+ + R + F + K G + T +S+DRE + + DKG P +++ + + VLD NDN P ++ PI + + + T+ A D D G NG + YR Q + + +G++ L ++L D L++I SD K V+ +
Sbjct: 519 ALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIR-YSLQNQDEHLTVDTMSG---TVCIQKTFDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHI-----LSESSSFSINPVTGEVFAQKPLARGR-----FHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFS----RSKYEIRTTEDILPG------IAIGSVGAMSKVKYSIYSGDQDHNFSIDEDTGKIYV---TRYLDADVHDTVLLNIQATLPSG---ESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSL-LDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVY-------RITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPI----VVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQ------LQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHV 1132 HSP 2 Score: 132.88 bits (333), Expect = 7.257e-31 Identity = 145/566 (25.62%), Postives = 250/566 (44.17%), Query Frame = 2
Query: 413 QTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELD---TSKFPQISLRLKSELDYETRKQYRLTLKACD---RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVREN-TLPGNLITIKVSDNDIGMNSKVNCEL---QTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKV 2074
QT V+ + N + +++++ D+NDN P+F E +T+RE + + SA D D + SY + S+ F ++ F Q L R ++ L + A D + S + I V D++ P F+++ Y++ E+ G + +V A K V Y+I + D D F I+ ++G+I + R L A+ ++ A + + + V I +ED N+ P + S+ + +RE+ L ++ SD D N +V + S I+ + + SL D+E+ + +K TD G PP+S++ ++ +H+ D+N+ +PEF++ Y + + EN+ T V ++ A D+D I Y + G +F ID G + TK + DREVI + + A D V P ++T +++ D NDN P I V + IG + A D DKG N V L R Q +F V G + + L+ L V V D+G + +V V++
Sbjct: 610 QTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEV-SYHILSESSSFSINPVTGEVFAQKPL---------ARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAMSK-------VKYSIYS-GDQD--HNFSIDEDTGKIYVTRYLDADVHDTVLLNIQAT---LPSGESNQTQVVIFIEDHNDNPPQFS--SSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSL-----LDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRI-TNGSEYFGIDEKLGNVYTKRSI-DREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSV-------LYRAQLQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRI 1136 HSP 3 Score: 93.2041 bits (230), Expect = 8.912e-19 Identity = 187/781 (23.94%), Postives = 322/781 (41.23%), Query Frame = 2
Query: 110 KPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLK---FSSLKFNVDSQFLQIND-NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS-SNKFELDTSKF---PQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELI---IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI---DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAI--LSTNERVEVRENTLPGNLITIKVS------DNDIGM-NSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYS-LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENM-ISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTN-VTVKVLDENDNKPQWMNPNPINPEYNIT--RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATK 2362
K K++++ LI IF F C T TV E + IG I + F S+FL++++ +G+++ +D E + F V V + + ID L ++++D NDN P F+ + + E + S +L + D D + L+ + +N F+L + K Q L + +LD E R +Y L ++A D + I++ D NDN P+F+++ Y S+ N GS ++TV A D D G+ + Y+I AP++ F I S SG I L T V+ SD +P V ITV P + I L + + EN+ G+++ +VS D + + S C QT+ + ++Y L D E+ G + L+ I D+N+ +P++ +SL T ++ L D IRYS LD + ID +G I N + D + I F A D + +++ + D P F + + + E+ I T L+ ++ A ++ GN+ ++ + +L + E + ++S G + ++ D E +SY V + TST+ +++++ D NDN P + PN EY++T E ++ V A D D+G G + Y I S+ FS++ +GE+ K L + L + A D +
Sbjct: 4 KNKWNILIFSLIFLIFPTF---CQCLT-KFTVPESAQIGTRIGWISGKREESAAPKYFVVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSK-----------FDIVAVKVEESGETIDIL---VEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSN----SNFAI-SQSGVITTTASLLPAS----THDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVA-RVSIAQQYRDTKLRLIGSSALCPQQTD----------QAHVYLLLLCGILDRETASEHHLKFLLEKDGQ--IIIEHPQLLTIGDINDNAPQWHSSQIHISLNR-TQGGSRTLTAKDPDLGQNGWIRYSVLDTE---LVSIDKETGRIFVPNTI-DCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLV-KVVANNSQCGNSKRIRY----SLQNQDEHLTVDTMS--GTVCIQKTFDFEKQKSYQTTVIATNANS---ETSTSLISIRLKDVNDNWPIFY-PN----EYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHIL-----SESSSFSINPVTGEVFAQKPLARGRFHLVVSAKDGGGQ 719 HSP 4 Score: 86.6557 bits (213), Expect = 8.794e-17 Identity = 180/781 (23.05%), Postives = 318/781 (40.72%), Query Frame = 2
Query: 158 ANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK----FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENT-DTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDIN-NYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPF-TATTKIIVTIEDE--------------------NDNAPIFGVIP--EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIIN--KNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL----DFDQIELTIIASDSATKPKMVMLKLIIN 2395
A EF + + T+ E QFI ++ L L +S ++ N+DS F ++ G + +D E L + S KV+ I + V++++N+LNDN P F + + + E+L V ++ A D D A R + + DSS + F +D +F ++ L + LD+E ++ LT+KA D T L I V D NDN P F+K Y+ ++ T G + A+D D+ G + Y++ + F + SG + ++ A +R L T V A D+ + VPV + + + P E+ E R + + I +++ + + + + +Q + K L+ + D E ++ + + V + D N+ P F + Y +SL+++ A K+ Q+ A+D+D E G+ ++I +SG N+V +I N + +DA +D F AT +I+V D + +AP F V+P E V E+ ++ ++ A++ N + + L K+ K+ K G + LD E+ ++ + V D + V+ +DE P Y + I+ E V +QA D D G +G +KY I + +Q ++E +G IRL K L + ++T++A S TK + L I
Sbjct: 1828 APLEFLKQTYLS--TIDEGLPRGQFIAKLQPELAG-LTYSIVEGNIDSAF-SVDSEGVIRTNLELDREILERYS------------LKVIGTGSGQQIGT-RVDVRVNNLNDNVPSFP-MSKPRRVPENLRVGSYVATVGAKDVDNLAPLRY--FLVSDSSGQTPTHFNID--QFTG-TIHLTAPLDFEVLPEHTLTIKATDGSFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDA--RGALTYSLGQGSS----SIFRVAPESGALFMKVLPPAGERYLVT--VTATDNGVPS-FSTSVPVSVIIGEAEPTDKPGF------EKAEFRFEVMENSKIGLQIGNLSGEESREFHYRIQDPEASKIFSIDKFGRLFVAGPI---DREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSG--------ENGRVSYRI--LSG--NDLNIVTLNPDTGSIQLNEW-NDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFF-VLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSL------KEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNGRSAVVPLKIVVEPVDE-------FAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISD-----RQSTVKIEEHTGIIRLQKPLVSRRNLTIEQITVVAYSSPTKQSKTTVYLEIG 2535 HSP 5 Score: 63.1586 bits (152), Expect = 1.363e-9 Identity = 156/663 (23.53%), Postives = 270/663 (40.72%), Query Frame = 2
Query: 413 QTKVLVNDRNDFIDSLTVNLQINDLNDNTP-LFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNF-YKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI--DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHV---------VAKDSDFN--NPQKE-KVPVEITVEDINNYYPVI-AILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCE--LQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL--DEKGK--AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMIS-TRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLD-ENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ 2323
Q +V ++D +D T+ + + + P + ST +T+ E++ + + + E+R ++ + ++ KF ++++ L L E E LT DSCT + + V D+NDNKP + ++ I E++ G ++ A D D G G + + D+ LDL+ +G++ L RRL++ Q V V K+ + + NPQ E K P+E + Y I L + + + L G +T + + +I V+ E ++T ++D ++L++ YSL K +GS + R V V + ++N+ P F + + EN + V + A D D A +RY L D G+ F ID +G I LD EV+ A D D FT T + + D NDNAP F + + TV S + ++ A D D T + Q IF V+ E ++ L E Y + V D G +TS V+V + + E +KP + E+ + N + +Q + E+ YRI +P+ + +FS+D+ G + + +D +Q
Sbjct: 1600 QRFTIVAQKDDELDYSTLKIHVEPVFTEPPKISSTSCGVVTIEENVGIE---DFKRILATGMTEESR---FRFQGNAPKFSINSTTGSISVLPLDREASQEHLLIIILTDGGSRNDSCTVR---VTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDLV------PETGDLVL-RRLSSLQSWKIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQ---TYLSTIDEGLPRGQFIAKLQPELAG--LTYSIVEGNIDSAFSVDSEGVIRTNLELDREILER----YSL------------------KVIGTGSGQQIGTR-VDVRVNNLNDNVPSFP-MSKPRRVPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQFTGTIHL-TAPLDFEVLPEHTLTIKATDGSFDTFTNLT---IFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDARG--------ALTYSLGQGSSSIFRVAPESGALFMKVLP-PAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFE-----KAEFRFEVMENSK---IGLQIGNLSGEESREFHYRIQDPEASK---IFSIDK-FGRLFVAGPIDREQ 2192
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 148.673 bits (374), Expect = 8.665e-36 Identity = 166/633 (26.22%), Postives = 280/633 (44.23%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC-----TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVL-VHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDS---GEIRLVKELDFD 2320
V + + D+NDN P+F++ +T+ E++ + ++ A D DF ++ Y + SS L T + + L+ +D K +T +D + L I+V D ND+ P +++ EN G V V A D+DSG G++ Y+++ D F I+ +SG I+ + L Y+ V A+ D P + + ++DIN+ P N V + E G+ +IT+K DND + K+ ++ + F +L + L+ + +V+ I TD G R V+ V I D+N +P F + V + E++ V+ L A D D A I YS+D FF+ID SG I + LDRE T A D P +T+I V ++D NDN+P F T+ E++ +++A DAD G N V++ L ++ + +Q G + LDRE F L + RD+G ++ ++ +T+ + D NDN P + ++ + I V T+ A D D G+N I +RI + +F ++ED+ G +R++ +FD
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVH-YSMASSSGIGGL-TIDYSTGEVTLRERID---AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED------FIIDEDSGLIKTTKLLDRETTARYSLKVTAR--DMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYN--VTISEEMPRGSQIITLKAVDND--EDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVR-VEISATDQGG---LQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDS--SQFFRIDPSSGDISVSS-DLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNES-SSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTF---EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFG---GADAKLFDIEEDAEQNGVVRILTRAEFD 602 HSP 2 Score: 145.976 bits (367), Expect = 5.197e-35 Identity = 172/660 (26.06%), Postives = 286/660 (43.33%), Query Frame = 2
Query: 209 EEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQIN--DLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPND-----LDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDIN-----NYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKA----FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE----GFIETL--QSLDRET-FESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKP 2098
E+F N G + Y++ L + + G+VTL++RID +NS I + D S TV L IN D+ND+ P ++ ITL E++ + + A D D S N I Y +E S + F +D + +L LD ET +Y L + A D + T + + ++D NDN P F K Y V+I E GS ++T+ A D D + Y I+ + LD+ I S SGE++ R+ + V +D Q V V + ++D+N N +P V++ E++ G +IT+K D+D G N+++ + + Q + + ++ D E S + +D SPP +T + V + D+N+ SP+F Y ++ E+ T LQ++A D D + + Y L+E + F++D SG ++ + LDRE IV FA D +A ++I +T+ D NDNAP F + + + EN +G + A DAD+G+N+ + F + K+F + ++ G + L D E + E+ ++++ V + V D NDNKP
Sbjct: 43 EDFGTN---GKVHYSMASSSGIGGLTIDYST--------GEVTLRERIDA----KNSPI---------TAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDED-SGPNGIIKYSMEGSED-FIIDEDSGLIKTTKL---LDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADREVFSILDIGDQGAILSVSGELK---------RQDHKVRVEISATDQGGLQGRCV-VNVFIDDVNSAPYFNDHPF--------SVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS-----QFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSS-KLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGAD-----AKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFEL---QASSGQLSSTVPVRIHVSDVNDNKP 639 HSP 3 Score: 144.821 bits (364), Expect = 1.316e-34 Identity = 143/537 (26.63%), Postives = 245/537 (45.62%), Query Frame = 2
Query: 782 IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMS--GWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTI-EDENDNAPIFGVIPEFTVK--ENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSAT 2359
I V D NDN P+F + Y V+ILEN +++ TV A D+D G G V Y++ + + I I+ ++GE+ L R+ A + V + D P VP+ I V DIN++ P + ++ + + + EN G + + D D G N + + E DF + E+ + + + D E+ S + D G+P +T ++ V + D+N+ +P F + Y V++ E ++++ L A D D I Y ++E + F I + G I + + L R+ + V + D + +V + D+ ++AP F P F+VK E+ + L A D D+G+N+++ + + + + F + G I LDRE ++++ V D P+ TST + V + D NDN PQ+ + + I+ I + V A D D G NG + Y ++ + +F LD SG +R+ +LD +Q I L I A D T
Sbjct: 4 ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSG---IGGLTIDYSTGEVTLRERIDAKNSPITA---VIRAKDGAQPALSSTVPLTINVIDINDHAPTL--IAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGII--KYSMEGSEDFII---DEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVRV-----EISATDQGGLQGRCVVNVFIDDVNSAPYFNDHP-FSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI--------DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSS---SYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGT 510 HSP 4 Score: 99.7525 bits (247), Expect = 7.649e-21 Identity = 106/405 (26.17%), Postives = 185/405 (45.68%), Query Frame = 2
Query: 410 IQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS-----CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVR-----SFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDE 1588
++ ++ D+ VN+ I+D+N + P F+ ++ + E P+ Y + A D D RI Y + DSS F +D S + + S+LD E R + + + A D S T E+I+D D NDN P FT + Y +I E+ G+ + V+A D D G G+V Y ++ + IQ F ++ SG +R+ +L Q + + A+D P + +T+ D+N+ P LS + + + EN+ G+ + TI D D G N+ ++ + D +L +E+ VR FD+E+ K SG S+ V +H++D+N+ P K + ++ +N ++ + A D D A++ Y L+E
Sbjct: 292 VRVEISATDQGGLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARI-VYSI-DSSQFFRIDPSSG---DISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILD--DINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDR--GTPSLSAASEITLTLSDVNDNAPTFEQLSYD--LYIAENSPVGSTVGTIVARDADEGDNADIS--FRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQ--LSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPDQNATLEYFLEE 680
BLAST of Protocadherin vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 129.413 bits (324), Expect = 8.048e-30 Identity = 172/658 (26.14%), Postives = 296/658 (44.98%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC-TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVE-DIN----NYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVN-----CELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQ----LNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIG-RLTATDADKGN-NSQVEFVLLKTLARKQEVQKIFSVSKEGFIETL-QSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIH-NPKPNSKQPVFSLDEDS-GEIRLVKELDFDQIE---LTIIASDSATKP 2365
TV + I D+NDN P F + T+ E V S+++ SA DRD S RI + L + + F+L+ + L + S+LD E Y+L +A D TD I V D ND+ P F K + + + + + S ++ + D D + + I N+ + F I+SN+ ++ L+R + Y V A D F K K+ ++ + + DI N ++A S V + E++L G +T K+SDND G VN +++ +ID++ K + L +F ++ S C + + V I ++N+ P+ + + +VS+ EN T+ Q + A D D I++ + + F+ID ++G + T LD E++ A D F I+VT+ D+NDNAP F + T ++ + IG L A G+ N +E+ L + +V +++ + I TL + LD ET + L V +D G P+ T V + V+DENDN P++ + + E V+TV+A D D+ G + Y + + + PV +S G++ + + +D+++I+ L +IA D P
Sbjct: 2697 TVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIR-FSLVEENPYFDLNENSG---WLTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDL--HLPSTSPILHFSIKDDDLSPNNVSQFFIPKGNEEGV---FWIDSNN-DLLLKRPEIVENKMQYQLKVTAFDGVFETSTKVKINLKSSKDSDIRCPEANKTVILAENSKKGTVVLGESSLLGPNVTFKLSDND-GNVFVVNFRNGIVKVKESDQIDYE---KNQQL---------EFHRLTIQDNSEVCKE----------LITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDAD-FDEIKFRMVDDFGGLFQIDDINGVV-TVVKPLDSEILGFFNLTVVASDG---EFEDKATILVTVIDQNDNAPTF---EKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYL-----KPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVG---KVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPP 3305 HSP 2 Score: 128.642 bits (322), Expect = 1.362e-29 Identity = 166/654 (25.38%), Postives = 300/654 (45.87%), Query Frame = 2
Query: 488 NDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLED-SSNKFELDTSKFPQISLRLKSELDYETRKQYRL---TLKACDRDSCTD-----KELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVS-DNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDM--NEYSPEFKQLIYEVSLRENTATNTKVLQLNATD-----RDGAASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTK-----IIVTIEDENDNAPIFGVIPEF--TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIET--LQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ-IELTIIASDSAT 2359
N ++P+FS+ + + + E P+ ++ A D D + N Y + D + + E+ T + + S+L +++ + LK D+ T K + + ++D N++ P F + Y + I EN G + V A D D G+ G + +++ N+ + I++ +G ++L + L + ++TF ++A D F P + V + I+VED+N+ P + + R + E+ G ++ + D DIG NSK+ L +E K+ F++ ++ A D+ + SI+ D G P ST + V + D+ N + EF + E S+ EN+ T+V+ + A + + A ++ Y + G F ID G ++T ++ LDRE A D+ D + + + + I D ND+ P+ P + +V EN + +I ++ ATDAD +N ++ K + + Q F + G+I T ++ LDRE + L V + D G+ + ++ V V VLDENDN P + I+ ++ K + + A D D GEN R+ Y I FS+D ++G I + + D+ LT+ A+D T
Sbjct: 602 NKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDED-TGYNGFIRYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLG--NNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGF--PMRVSVTNLTISVEDVNDNPPKCVV--QHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSE-KVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQ-KGTVRTTHL-LDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPV-AKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKI--ERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFT--QAIHHYSVRSKFAGK---LCRIFAVDADEGENARLTYNI-----TEGDARFSID-NNGNIIASEAIHGDESYALTVQATDHGT 1231 HSP 3 Score: 103.605 bits (257), Expect = 5.551e-22 Identity = 138/581 (23.75%), Postives = 257/581 (44.23%), Query Frame = 2
Query: 764 TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLER---------------RLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSAS------------------IKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQ-KIFSVSKEGFIETLQ-SLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIK-----YRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSAT 2359
+K++ I++ D ND+ P+F+ + + + + G ++V V+A D+D G+ G ++Y + L+ IN+N+GEI L L ++ +++ + P K K P+ I E N + PV + S E VEV E+ G ++ ++ +D D G N + + + ++L + D +SG++ AS + D+G+P KS+ +++ + I D+N +SP+F ++ Y + + EN + ++ A D DG I++SL +++ + ID +G +K LDRE + F A D + T + +++ED NDN P V + E++ + + A D D G NS+++F+L ++V +I S FI + LD + L + V D G ++TS ++ V+++D N + + + E ++ V+ ++A +T G+ ++K YRI P FS+D+ G +R LD + +T+ A DS T
Sbjct: 474 AEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLE------INANTGEITLVEVPKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPK-PI-IIQESENKHSPVFS--SFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVL-------------TVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLK-SLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLL-----NSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNH-LAIEFDDVAKEASVYENSEIGTEVIMIEAKET--GDEQKVKAENLEYRIIG---GDGWPHFSIDQ-KGTVRTTHLLDRETKSAYWITVEARDSKT 1018 HSP 4 Score: 84.7297 bits (208), Expect = 3.611e-16 Identity = 151/676 (22.34%), Postives = 291/676 (43.05%), Query Frame = 2
Query: 434 DRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE-DSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNID---APNDLDLIQTFGINSNSGEIRLER--RLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSL-------ASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKI-FSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELV----MTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIASDSATKPKMVMLKLII 2392
D F L + ++D+ND+ P F E I L LP + S D D S N + + + + F +D++ L LK E + QY+L + A D T ++ I+++ D+ + V + EN+ G++V+ G+ L+ N+ + ND ++ F +N +G ++++ ++ + + FH + +N + K + + +E++N+ P I+ +V + EN LP S++ +++ E +I F+++ L+ + V+ D E + ++ +D K+T +LV + D N+ +P F++ Y + + E+ + ++ A+ D +I Y L +F ++ +G I T LD E + + A D+ V P ++ +++ DENDNAP F VKEN S + + A D D + V + L + + F+++ G + QS+D E + Y L+V +D G+ P+ + + + V DEND+ P + + N+T ++ + E + + D D +NG + + +K F ++E E+ K+L++ D+ LT+IA D K L + I
Sbjct: 2789 DEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDLH--LPSTSPILHFSIKDDDLSPNNVSQFFIPKGNEEGVFWIDSNN----DLLLKRPEIVENKMQYQLKVTAFDGVFETSTKVKINLKSSKDSDIRCPEANKTVILAENSKKGTVVL---------GESSLLGPNVTFKLSDNDGNV---FVVNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQ---DNSEVCKELITVVIENLNDNRP--KIIEKLLKVSIDEN-LP-------TSEDARQYITRIVAEDADFDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDGEFEDKAT---ILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTG-ILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTF-------DDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNG-APFTVEIQGDGAKS--FKVNEKL-ELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDCPLTIFI 3418 HSP 5 Score: 84.3445 bits (207), Expect = 4.348e-16 Identity = 104/415 (25.06%), Postives = 180/415 (43.37%), Query Frame = 2
Query: 701 LDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYT-FHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNC---ELQTESKID-----FQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQ-------LNATDRD----GAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTAT--TKIIVTIEDENDNAPIFGVIPEFTVKENMI----STRLIGRLTATDAD 1861
LDYE ++ R ++ + + +++ DENDN P F + + E+ ++ TV A+DKD G+ G+V Y+I + N+ L F I++ SGE+RL + L + + + + A DS N+ + E + + + + N + + ++T PG L+ + + + NC E+ T S LK ++++ A V S + + K V+ I N++SP F++ +Y ++REN T + VL ++A D D G R L K + F +D SG I+T+ + D E ++ F A D P + + I+VT+ DEND P F P ++ +MI + +G TA D D
Sbjct: 1428 LDYEAARRIRAVVQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESL---FKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAANSLKDE---MSLHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTPVLVLNALHHGTVSYKLEPNCTFFEVHTLSGAVHLATWLTKLKHRKSVECTAIVESTEGQQDIAK-------------------VIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRM-LSPKDEQMFSVDQYSGAIRTQ-MSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRF---PSNSLDISMILPTANGVSVGGQTAQDMD 1812 HSP 6 Score: 78.9518 bits (193), Expect = 1.861e-14 Identity = 156/625 (24.96%), Postives = 262/625 (41.92%), Query Frame = 2
Query: 617 SYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE-----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVT-------VNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP--VEITVEDINNYYP--------VIAILSTNERVEVRENTLP-----GNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFK--QLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDRE--VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNE------LVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTI-IASDSATKPKMV 2374
SYKLE + FE+ T ++ L + L T+ ++R +++ T+ + +I + N + PIF + Y+ +I EN TGS V++ V+A D+D G GLV Y + +P D Q F ++ SG IR + + K Y+F+V A D P++ +P + +TV D N+ P + IL T V V T G+L + D + +SK L+K + + + FD E + TD S ++ I+ ++ + +FK + Y SL ENT + L+ G +S+ +AFF I +G I + + LDRE I +V A +H+ +P A ++V IE+ ND PIF P + T+ + I T ++ D D+G+ V+ + E KI K + L S++ E E + ++ +D G V ++V+D+ P+ + T +I+K LV + + G I YRI + K+ FS+D +GE+RL + T + + T+PKM+
Sbjct: 1604 SYKLEPNCTFFEVHTLSG---AVHLATWL---TKLKHRKSVECTAIVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDE---QMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMG-QPPRRSLMPSLIVVTVIDENDEPPRFPSNSLDISMILPTANGVSVGGQTAQDMDSVGSLRYF-IKDQSV--------PFSVDSKTGDVLVKDSNGISDMTKL--FDLE--------VFVTDG-----KQSASYVMKISTISTENSKFKFTRNEYHTSLIENTTLPPGSIILSVATI-GDKLDHFSIVNPHEAFF-IHPGTGVISSSGIALDREKSAIIRLVVQAKSHEK--NPVMARALVVVGIENINDETPIFMGTPYDITIGHSDIGTVVL-EPKVIDNDEGD------VVTISSENMPEYFKIVG-GKVVLGKKLPSIEEEDLE-FNFKLIAKDNGSVHRVEEP-VKIRVVDK---------ARPVFSQNVYTAVISKESTKKSTVLVKVMAKSSLQSKSKGLIGYRILD-----KKSPFSVDFLTGEVRLNNLKMLAETNYTFEVEAREVTRPKMI 2166 HSP 7 Score: 76.6406 bits (187), Expect = 9.569e-14 Identity = 168/689 (24.38%), Postives = 275/689 (39.91%), Query Frame = 2
Query: 431 NDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRD------FSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSIL-ENTDTGSLVVTVNAYDK-DSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLE--RRLAANQRKLYTFHVVAKDSDFNNPQK-EKVPVEITVED-INNYYPVIAIL----STNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIR-------YSLDEKGKAFFKIDHMSGWIKTKNVVLDREVI---ETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLL----KTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDK-GKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKPKMVMLKLIIN 2395
+++N + V + I ++ND TP+F IT+ S + + D D S+EN E +K+ K L K P I E D E + L A D S E + ++ + +P+F++N Y I E+T +++V V A S GL+ Y I LD F ++ +GE+RL + LA YTF V A++ P+ K VEI V+ I + PV L ST E + + L+TIK + +D N + L I+ + D+E Q + T SG S++ +V I D+N+ PEF + + ++ T + ++ATD D S+ Y + + + F I +G + V +++ V N D FTA K++V I P V + +T + T A KG ++F L + +E + K G I + L+ + Y + + V D G+ +T +T+ V+D ND P ++ P +I+ + + VM V A D D EN I+Y + + S+ FS+ G I + K+L+ + LTI A+DSA P + +N
Sbjct: 1959 HEKNPVMARALVVVGIENINDETPIFMGTPYDITIGHS-DIGTVVLEPKVIDNDEGDVVTISSENMPEYFKI--VGGKVVLG-KKLPSIE-----EEDLE----FNFKLIAKDNGSVHRVEEPVKIRVVDKARPVFSQNVYTAVISKESTKKSTVLVKVMAKSSLQSKSKGLIGYRI-----LDKKSPFSVDFLTGEVRLNNLKMLAETN---YTFEVEARE--VTRPKMIAKAQVEIIVKSGITTHAPVFEKLKYTASTPESTSIGQR-----LLTIKATTSD--ENDTIEYSLSGSKDIEIH-----PETGDVTITGQLDYEKTQKYDLKLVATSSGKQ-VSSEAEFIVLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTTNSLDEESQKLLYKIVDGDETLFNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGM---FTAYAKLVVEILRSGSMQPPPRFEQSHYVANALENTIVNKSALLTVAVKGGVPPLQFSLAPTTSSNSSTSKEAWPVAIDRKTGRIHVSRVLNYHRDKRYQIPLVVEDATGRRAFST---LTLSVIDINDKPPFFVLP---FYSTSISESAKEGDTVMMVSATDDD--ENDTIEYSLLD---GSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVN 2597 HSP 8 Score: 76.2554 bits (186), Expect = 1.497e-13 Identity = 104/406 (25.62%), Postives = 172/406 (42.36%), Query Frame = 2
Query: 701 LDYETRKQYRLTL---KACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNS-KVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLK 1900
L+Y K+Y++ L A R + + L + V D ND P F FY SI E+ G V+ V+A D D D + Y++ D Q F ++ G I + ++L + + A DS N P VE+ + + P + +++ V E+ GN+I +V + ++ + +E F + + + S D E +I+ +G T +V V I D+N+ +P F ++ E+ A T V +A DRD + S IR+SL E+ +F ++ SGW+ + LDRE I+ A A D F + + D ND+ P F EF + ++ ST I + D D N+ +F + K
Sbjct: 2465 LNYHRDKRYQIPLVVEDATGRRAFS--TLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDEND--TIEYSL---LDGSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDS-ANPPHHATTTVEVNIASESVKVPRFS--NSHYLFSVMEDADVGNVIG-RVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAGGVHAIT--TVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEE-NPYFDLNENSGWLTVAS-QLDREKIDHYKLIARATDE--GGFNTDLPFTIVVSDVNDSPPQFEK-EEFNIDLHLPSTSPILHFSIKDDDLSPNNVSQFFIPK 2852 HSP 9 Score: 70.0922 bits (170), Expect = 9.831e-12 Identity = 79/307 (25.73%), Postives = 132/307 (43.00%), Query Frame = 2
Query: 1424 SVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYS-LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPE-FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKI--FSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE 2329
++ + + D+N+ P F Y S+ E+ V+ ++ATD D +I YS LD FF + G I T L+ + T+ A D+ P ATT + V I E+ P F F+V E+ +IGR+ + ++++ + + +E FSV + G I SLDRE + + +R + T VTV + D NDN P + + I+ V A D D +GRI++ + + P F L+E+SG + + +LD ++I+
Sbjct: 2490 TLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTIEYSLLDGSESQFFSVHPRQGTI-TVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQME------TEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMT--IRADAAGGVHAITTVTVDIGDVNDNAPAFHGD---YERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSL-----VEENPYFDLNENSGWLTVASQLDREKID 2779 HSP 10 Score: 61.6178 bits (148), Expect = 3.853e-9 Identity = 146/610 (23.93%), Postives = 236/610 (38.69%), Query Frame = 2
Query: 680 SLRLKSELDYETRKQYRLTLKACDRDSCTDK----------ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGL---VMYNIDAPNDLDLIQ---TFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQK-EKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPE----------FKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKG-KAFFKIDHMSG--WIKTKNVVLDREVIE--TIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD--FDQIE--LTIIASDSATKPKMVMLKLIINN 2398
++R LD ET+ Y +T++A RDS TD + I + D ND++P+ K Y S+ EN+ ++V V A D D D +M+ I+ + + T G + SG RL+R + + D PQ V V + V D N+ P + V + G L I D D G N+++ + TE F + + S A + + +++ TD G+P + + +V + P K+ Y + + + V +L A+D DG + +S+ + F + +G + K +L R + V + A D + +I+ + + P F T V E + I L A+ G V F L E KI G + ++ LD E V V+ AT +V + DENDN P ++ + ++++ TV AFD D GENG + Y I + +++ +F +D SGE+RL K LD +E L I A DSA + L I N
Sbjct: 992 TVRTTHLLDRETKSAYWITVEA--RDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSI------CDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSK---FAGKLCRIFAVDADEGENARLTYNI-TEGDARFSIDNNGNIIASEA------IHGDESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDADGD-ELWWSISSGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAWDH--------STVIIQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLV-FNLFSVDDVAME-DKIRVEPSSGNVIVMEPLDYEAARRIRAVVQVQQANMKSFAT---FSVNINDENDNSPYFVGHTAF---AFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVS---GNEESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAANSLKDEMSLHIRN 1563 HSP 11 Score: 56.9954 bits (136), Expect = 8.646e-8 Identity = 121/517 (23.40%), Postives = 214/517 (41.39%), Query Frame = 2
Query: 452 DSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSM-SLESAFDRDFSAENRIE-SYKLE--DSSNKFELD-TSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASV---RSFDF--ESGQ---------VKSASIKCTDSGSPPKSTDRS-VLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GAASIRYSLDEKGKAFFKIDHMSGWIKTK------NVV----LDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMISTRLIGRLTATDADKGNNSQVEFVLL 1897
D L V ++I D ND+ P+ ++ E+ P N + +E+ D + +K+E D + F +D TS + I+ LD E + ++ L + CD C++ +I++V DENDN P FT+ + S+ + + + A D D G+ + YNI + F I++N I E A + + Y V A +D P ++ + V+ S ++ +N+ P I+ K SD I ++ L T K++ E +S++S FD ++GQ +K ++ S + ++ D S V++ ++ P+F Y+ + E A T++ L A+ G + ++L F +D ++ K + NV+ LD E I A + F + V I DENDN+P F F V E+ ++ +TA D D+G N V + ++
Sbjct: 1028 DVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGY--ITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSV--RSKFAGKLCRIFAVDADEGENARLTYNITEGD-----ARFSIDNNGNIIASE---AIHGDESYALTVQA--TDHGTPGQQFAATRV----------VLTANSAGQKPRKSKNSPPE--ISGKKSDYVIPISDADQVGL-TVGKLEASDADGDELWWSISSGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAWDHSTVIIQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLVFNL-------FSVDDVAMEDKIRVEPSSGNVIVMEPLDYEAARRIRAVVQVQQANMKSFATFS---VNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIV 1507 HSP 12 Score: 56.9954 bits (136), Expect = 1.041e-7 Identity = 81/340 (23.82%), Postives = 141/340 (41.47%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYALPDKLKFSSLKFNV--------DSQFL--QINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVND--RNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRD-------FSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD-RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGD------LGLVMYNIDAP----NDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINN 1132
VKE K + + +K D F ++ + + D+ L IN NGDV + + ID E + + N+ KV+ D R + + + D ND+ P F T ++E + + + S D D F+ E + + K + K EL T+K +L+Y + +Y LT+ A D + TD L I ++ + + P +++ L+N ++ + A D+D D GLV +I +P + F ++ N+G+I + + + L+TF+V DS FN VE+ V I+N
Sbjct: 3225 VKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKI-KKYNL-----------KVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKSFKVNEKLELLTAK----------KLEYRKKDKYLLTVIAKDVKGKTTDCPLTIFIRQTSRHAPTMKPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRFGLVEGSIQSPRAQVQESRSTHLFRVDPNTGDIWSDHSIT---QGLHTFNVTVTDSKFNTVSY----VEVHVTSIDN 3535 HSP 13 Score: 55.8398 bits (133), Expect = 2.095e-7 Identity = 139/666 (20.87%), Postives = 280/666 (42.04%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD-----RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSG--WIKTKN-VVLDR-EVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLK---TLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLE---VGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP-NPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPKMVMLKLIIN 2395
T+ L + D+ND P F + ++ ES ++ + SA D D EN Y L D S + + Q ++ + +L+++ LT+KA D + T E +++ E+ P F+ + Y S++E+ D G+++ V + + ++ + + + D F + ++G+I ++ L ++ + + A D V + + D+N+ P A ER + E+ G +TI D D + ++ L E+ F L EN L D E + TD G +TD + ++D+N+ P+F++ + + L + + + +L + D D S + + F + G WI + N ++L R E++E + A+ F +TK+ + ++ D+ + E + L A ++ KG E LL T +F V+ + G ++ +S + ++ LE + ++D + +TV + + NDN+P+ + ++ + N+ + + + + A D D E IK+R+ + +F +D+ +G + +VK LD + + LT++ASD + K +L +I+
Sbjct: 2490 TLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDD---ENDTIEYSLLDGSES-QFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVE--VNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTI--VPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRA---DAAGGVHAITTVTVDIGDVNDNAP--AFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPY-FDL---NENSGWLTVASQLDREKIDHYKLIARATDEGG--FNTDLPFTIVVSDVNDSPPQFEKEEFNIDL--HLPSTSPILHFSIKDDD------LSPNNVSQFFIPKGNEEGVFWIDSNNDLLLKRPEIVENKMQYQLKVTAFDGVFETSTKVKINLKSSKDS--------DIRCPEANKTVIL-----AENSKKGTVVLGESSLLGPNVTFKLSDNDGNVFVVNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNSE---VCKELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDE---IKFRM----VDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDGEFEDKATILVTVID 3105
BLAST of Protocadherin vs. Ensembl Celegans
Match: cdh-3 (Cadherin-3 [Source:UniProtKB/Swiss-Prot;Acc:P34616]) HSP 1 Score: 127.872 bits (320), Expect = 2.593e-29 Identity = 171/632 (27.06%), Postives = 282/632 (44.62%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFST--IEQTITLRESLPVNYSMSLESAFDRDF-SAENRIESYK-LEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD----SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVD--PFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ 2323
V + + D ND P F T + L E V+Y + + S+ D +N + +Y L +++ F ++++ +SL LD E + L ++A D S T K ++I V D NDN P F + Y + I EN+ GS ++ + A DKD + Y++++ +++ + F IN +G I + ++ + + + F V D + + KV VEI VED N+ +P+I N + V + T +I I V D D + K + + + + K L + VR T S L H + P F + + VS+RE+ V + N SIRYS+ + +++ +G +KTK+ + E E +VF Y D P + TK + I D NDN+P F + F V EN +LIG + A D D+ +S+V + ++ A + F V++ G IE+++ LDRET Y L V D GK +T V V VLDE+DN P++ + ++ RI E V+ + A D D N R + + F +DE++G + + LDF++
Sbjct: 1634 VIIHVTDENDEAPRFITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTSLFAVNSTTGDILSL---IPLDREESSLHELLIEAKDAGIPSLSATSK-ILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKDKD--AELQYSLESNDEITI--PFRINVATGWITVAGKVNREENEEFRFFVKVTDGE----KSSKVIVEIHVEDFNDNHPMIN--DRNSDIFVPDPTRSVEIIHVINVHDLDKSDHLKFSLNNSNLNLSENGEITLKSPLQTAVPVR---------------VTVSDDAGHVAFMEYLFHPHSRKHF-PVFVEKLDTVSVREHDEQELAVFKANGD------SIRYSIVSRCSDHLEMEKSTGILKTKSSLDAEEYSECLVF--IIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENS-GPKLIGHVIARDIDR--SSRVFYEIVGGDANHE-----FMVTESGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRIFHVEVPEDV-RI---GEPVIQLSASDADEHSNHRFEL-----DGGGEGIPFRVDENTGMVFVNDSLDFEK 2210 HSP 2 Score: 89.7373 bits (221), Expect = 1.129e-17 Identity = 159/681 (23.35%), Postives = 275/681 (40.38%), Query Frame = 2
Query: 419 KVLVNDRNDFIDSLTVN----LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVED---------------INNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEI-RLVKELDFDQIELTIIASDSATK--PKMVMLKLI 2389
++L+ ++ I SL+ + + D+NDNTP F I + E+ + + A D+D AE + ++ + F ++ + + + +++ E +++R +K D + + + I V+D NDN P+ + + + T + ++ +N +D D D L + S +GEI L+ +P + VPV +TV D ++PV + + V VRE+ L K + + I + C E + +LK K +L + E + I T + P ST + I D+N+ SP F Q +Y ++ EN+ + + A D D ++ + Y + + F + SG I++ LDRE A D T +IVT+ DE+DNAP F I V E++ + +L+A+DAD+ +N + E L E G + SLD E +SY ++V + D G + + TS V VK D NDN P + P EY N E + A D D+ NG+I+Y + P F ++ +G + R ++L + L + A+D K V+ L+
Sbjct: 1723 ELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKDKDAELQYSLESNDEITIPFRINVATG---WITVAGKVNREENEEFRFFVKVTDGEKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVEIIHVINVHDLDKSD----------HLKFSLNNSNLNLSENGEITLK-----------------------SPLQTAVPVRVTVSDDAGHVAFMEYLFHPHSRKHFPVF--VEKLDTVSVREHD-EQELAVFKANGDSIRYSIVSRCSDHLEMEKSTGILKTKSSLDAE--------EYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKL-IGHVIARDIDRSSRVFYEIVGGDANHEFMVTE--SGQIESVRD-LDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRIFHVEVPEDVRIGEPVIQLSASDADEHSNHRFE------LDGGGEGIPFRVDENTGMVFVNDSLDFEKKQSYRIKVKLTD-GAWLIETSLFVNVK--DVNDNAPIFEKP-----EYLFISEENSAE-IGQFHASDMDSENNGKIRYSV-------TSPYFKIEPSTGVLSRFRQQLPQPLMSLKVTATDHGVPRLQKTVLAHLV 2330 HSP 3 Score: 69.707 bits (169), Expect = 1.294e-11 Identity = 73/312 (23.40%), Postives = 136/312 (43.59%), Query Frame = 2
Query: 1535 LNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIK--------TKNVVLDREVIETIVFNAFAHDA--YVDPFTATT-----KIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQV-EFVLLKTLARKQEVQKIFSVSKEGFI--ETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW------MNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIIN 2395
N T + +I++S+ E K I H+ I + D + +E V + ++ +D T+ I++ + D NDN+PIF + + + E + ATD D+G N + ++ L+ +LA + V +GF+ E LDRET + Y++ + D+G +++S ++ + +LD NDN P + +N N + N + ++ A D D+ EN + YRI P S+ +FS+ +++ + + E + A DS P L +++N
Sbjct: 21 FNFTHQFSEETIKFSVSEDAKLNTIIGHLEAEIGYTYRLSRGNSKIKFDEQTLELSVSSPLDRESENAIDMLIITSPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNFGIRSLTLNWNGL-----------PNTKLFSLNATDLDSNENSLLTYRILPSGPTSE--MFSISDENILVTQNNTECLQRCEFVVEARDSGVPPLSTTLNIVVN 319 HSP 4 Score: 65.4698 bits (158), Expect = 2.566e-10 Identity = 58/200 (29.00%), Postives = 95/200 (47.50%), Query Frame = 2
Query: 1721 TATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINK-NELVMTVQAFDTDAG-ENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
T T+ I + ++ N ++PI I E V EN + GR+ A D D G + V + K L + + IF + S G + +L++ D E SYT E +D G T+ T+ + D NDN P++ Y I K NE V VQA D D +N +++Y + N F LD+++G++ ++++
Sbjct: 614 TQTSIITLIVKPLNQHSPICQ-ITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSY---KILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKF------GSRYYTATISGKSNETVAIVQANDNDVDVKNQKLQYHLLN-----YHDFFQLDKETGKVTTIQDV 798 HSP 5 Score: 56.9954 bits (136), Expect = 9.026e-8 Identity = 69/283 (24.38%), Postives = 120/283 (42.40%), Query Frame = 2
Query: 140 LILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFS----SLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT-SKFPQIS------LRLKSELDYETRKQYRLTLKACDR------DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI 937
LI + NF + + T +V E+ K N IG+++ + + S +KF+ + L ++ D + ID+ + +I + + + + D+NDN+P+F Q + + E+ P+ + + + A D D I Y+L DS +DT S F + L + +LD ETR Y + L A D+ SC LI+D+ NDN P F +++ N + + ++NA D DS + L+ Y I
Sbjct: 15 LIFFHLFNFTHQFSEETIKFSVSEDAKLNTIIGHLEAEIGYTYRLSRGNSKIKFDEQTLELSVSSPLDRESENAIDMLIITSPPSI------------------------IHILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLAT--VDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDI---NDNPPNF--GIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRI 266 HSP 6 Score: 56.225 bits (134), Expect = 1.510e-7 Identity = 41/138 (29.71%), Postives = 68/138 (49.28%), Query Frame = 2
Query: 731 LTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK-VPVEITVEDINNYYP 1141
L + +R++ + + V+ N + PI ++ +LEN G++ + A D+DSG G+V Y I +D D F ++S SG +R + A +++ YTF AK D P K P I +ED+N+ P
Sbjct: 604 LPVTLVNRNTTQTSIITLIVKPLNQHSPIC--QITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSD-DYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAK--DLGTPSKTTNCPATIFIEDVNDNVP 736 HSP 7 Score: 50.447 bits (119), Expect = 9.016e-6 Identity = 43/181 (23.76%), Postives = 83/181 (45.86%), Query Frame = 2
Query: 1103 VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA-ASIRYSLDEKGKAFFKIDHMSGWIKT 1639
+ + V+ +N + P+ I + V EN G + I+ D D G++ V+ ++ T+S + SL S+++FD E + + + D G+P K+T+ + I D+N+ P+F Y ++ + ++Q N D D ++Y L FF++D +G + T
Sbjct: 619 ITLIVKPLNQHSPICQI----TEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDVKNQKLQYHL-LNYHDFFQLDKETGKVTT 794
BLAST of Protocadherin vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 206.453 bits (524), Expect = 1.398e-53 Identity = 180/650 (27.69%), Postives = 309/650 (47.54%), Query Frame = 2
Query: 458 LTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL--EDSSNKFELDTSKFPQ-----ISLRLKSELDYETRKQYRLTLKACDRDSCTD---KELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQR---------KLYTFHVVAKDSDFNNPQKE-KVPVEITVEDINNYYPVIAIL---STNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYS-LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPE-FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGK-YPMATSTNVTVKVLDENDNKPQWMNPNPI------NPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
+ V +++ D+NDN+P F I+ ES + L++A D D + Y++ + NKF L T+ P + L LD E+R Y+L + A D S ++ + + D NDN PIF + Y VS+ E G+ VVTV A D D GD + Y + + F +N +G I R+ Q+ K F V A+D +P+++ + V + + D N++ P+I+ + V EN + G ++ + V D+D G+N + + + + +++ L++ +L+ + D E + ++ D G+P ++T +++ + D+N++ P F++ Y L E T + V + ATD D A + Y L +F +D ++G I T LDRE+ +T+ + A D +P A T++ V I DEND AP F + T+ E+ ++ +TATD D+G N V F L ++ R +Q F++ + G + T + LDRE Y + V RD+G P + + V + V D NDN PQ+ + I + + + + + K +++ V A D D G+N I+YR+ + + +F LD SG I L
Sbjct: 140 IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYL-----AETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARD--HGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTG-PLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQ--FALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLE----SGGEGLFQLDARSGAISL 775 HSP 2 Score: 196.823 bits (499), Expect = 1.715e-50 Identity = 229/798 (28.70%), Postives = 356/798 (44.61%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYALPDKLKFSSLKF----NVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQIS-LRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDS-----------------DFNNPQKEK------------------VPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSL----ASVRSFDFESGQVKSA---SIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKAF-FKIDHMSGWIK-TKNVVLDREVIETIVFNAFAHD-AYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMI--STRLIGRLTATDADKGN-NSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIIN--KNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSA-TKPKMVMLKLIIN 2395
V E+ + I ++ PD L S+ F D +FL G + L +D ET + + ++ V+D + ++ +Q++D NDN PLF + + E+ Y + A D D ++ + D +N F L+ PQ L L + LDYE + Y L ++A D T + +V D NDN PIF Y + EN + VVTV+A D DSG+ GL+ Y+I A D+D FGI+SN G IR R L R YT V A+D + +P+K + V V I ++D+N+ PV +S NE + + +I +K DND G N ++ L E++ D + + +SL +R D +++S+ +I D G PP+ST+ +L+ I D N+ SP F Y S+ EN + VLQ++ATD D A+ IRYS+ + F I +G ++ KN L+ E + A D A +P T ++ + I D NDN P F P V EN + + + + A DAD NSQV + L K+ +F + + G I L+ LDRE YTL + D G P+ + V V+V D NDN P + + Y+ T N V+T +A D D G N ++++ + + F +D ++GEI LD ++ LT++A DS+ T+P+ + L I+
Sbjct: 1832 VSEDLQIGHTISTLRAHDPDTL--GSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETKSK------------YELRIRVSDGVQYTEAY-ATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLN----PQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITA-GDVD--SEFGIDSN-GTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPV--FISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDY-LMKEAR-DEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGVVRVAKN--LNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFL------KEGDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQS-----YHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHR----FHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTIS 2585 HSP 3 Score: 185.652 bits (470), Expect = 5.060e-47 Identity = 195/766 (25.46%), Postives = 340/766 (44.39%), Query Frame = 2
Query: 266 LKFSSLKFNVDSQFLQINDNGDVTLKKRIDLE-----TLCQNSNICCGQFLCF-----IQTKVLVND-------RNDFI---------DSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFP------QISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLP---GNLITIKVSDNDI-GMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYV-DPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFE----SYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPN---PINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKE-LDFDQI---ELTIIASDSATKPKMVMLKLIINN 2398
+++S +VDS+F I+ NG + ++ +D E TL + C +F F Q K+ R +F+ ++ V + I D+ND P+F + +T + E++ +N + A D D I+ Y ++++ ++ + P LR+ LD E R Y L + A DR T+ +L+I + DENDN P+F Y S+ EN G++V+ V+A D D G G + Y+I D F I+ ++G +R+ + L + Y+ V A+D NP + + I + DIN+ P L + V ENT+P G ++T+ D D +NS+V L+ + D L + + +A ++ D E + ++ D+GSPP + V V + D+N+ P F+ Y ++REN + T VL ATD+D A +R++L + F ID +G I T LDRE A D+ + +P ++ + +++ D NDN P F V E + + A D D G N+ V + + Q F + +K G + T L +T +YT+ + D+G+ +++ +TV + +P + P N + ++ + +++ V A G G+I+Y I +D +SG + + ++ LD++ E+ I A+D T P + + LI N
Sbjct: 2062 IEYSITAGDVDSEF-GIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIM-ENVAINTVVIAVKAVDNDEGRNGYID-YLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLG---DQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPT--FLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLK---EGDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEISTA-TTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTI------SGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVIL------RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDS---LRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDT-PSLRSVTLITLN 2799 HSP 4 Score: 172.17 bits (435), Expect = 7.763e-43 Identity = 187/674 (27.74%), Postives = 301/674 (44.66%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFS---TIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK-VPVEITVEDINNYYPVIAILSTNERVEVREN----TLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKK-----------KENLYSLASVRSFDFESGQVKSA--------SIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAF-FKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYV-DPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKN----ELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPV-FSLDEDSGEIRLVKELD---FDQIELTIIASDSA 2356
VN+ I DLNDN P+F+ E TI+L E+ V + L DRD +RI SY L ++ N+ + + L L+ + E + L A D + L + + D ND+ P+F Y+ S+ E T + + A D D GD G + Y I N + F G + + L +R Y V +D+ P + VPV I V D N+ P ++ + EN T G L + D DIG N++++ L ++++ DF + + +E L ++ E G ++ + +D+G P V V +TD+N+ +PEF + Y V++ E + T + + D D + YSL + +A F +D +G + LDRE E A DA + P ++ I + + DENDNAP F E +V E + + R A+DAD+G NSQV F + + +++ I S++ ++ + LD E SYTL + D G ++T+ V V+D+NDN PI P I R I + ++TV A D D+G NG++ Y I +P Q F ++ ++G I ++E+D D LT++A+D A
Sbjct: 928 VNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRI-SYSLTNNPNQ-QFRIGPVTGV-LYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVF----PDGYLFVRAPLDREERDYYALTVSCRDA--GQPSRSSVVPVVIHVIDENDNAP--QFTNSTFTFSIPENAPADTFVGKLTAV---DRDIGRNAELSFTLSSQTQ-DFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGR-RLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSI--SAGNRRDTFHIDSITGSLYLH--KPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNP-------PIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRA 1574 HSP 5 Score: 152.14 bits (383), Expect = 1.172e-36 Identity = 160/626 (25.56%), Postives = 282/626 (45.05%), Query Frame = 2
Query: 683 LRLKSELDYETRKQ------YRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDA------------------YVDP------------------FTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKI----FSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATK-PKMVMLKLIIN 2395
L +ELD E + Y + L R S T ++ + V D+ND+ P F + ++ E+ G + T+ A+D D+ LG V + + +D F + ++G++ L L + Y + D Q + I V D N+ P+ T ++ EN G + I D D+G N++++ + ++ D L + + +L + D+E Q ++ D+G P ST +V ++ D+N+ +P F + Y + EN T+V+ ++A D D I YS+ + F ID +G I+T+ LDRE T A D Y P ++T K+ + I+D ND P+F E + EN+ ++ + A D D+G N +++++ + AR +++ + FS++ +G + + +LDRE SY L + RD+G+ P +T + + +++LDENDN P + +P ++ + +V+ V A D D G NGRI+Y I N FS+ ED+G +R+ K L+++++ LT+ A D A + P +L IN
Sbjct: 1774 LSTAAELDREAGPEEYEVEVYAIALGGQPRTSRT--KVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDT--LGSVTFLLMDGHD----GKFLLEPSTGKLILNDTLDRETKSKYELRIRVSD----GVQYTEAYATIQVSDTNDNPPLFE--DTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTA--RLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDS-NGTIRTRR-NLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKE--ARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVF---DPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHD---FSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTIN 2373 HSP 6 Score: 149.443 bits (376), Expect = 7.504e-36 Identity = 186/716 (25.98%), Postives = 306/716 (42.74%), Query Frame = 2
Query: 263 KLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRE-SLPVNYSMSLE-SAFDRDFSAENRIESYKL-EDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS--CTDKELI-IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVK-SASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLI-YEVSLRENTATNTKVLQLNATD--RDGAASIRYSLDEKGKAF---FKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSA 2356
++++S + + + F D G V + K ++ E L + S + L N D + LT+N I D+NDN P F + E ++P N L +A+D D N Y L E S+ F ++ S + L LD E + +Y LTL A D S T ++ ++VQD NDN P+F Y ++ EN +G+ V+T A DKD G + +N+ + + F I+S +GEI L + +Y ++A+DS P+ V + I+V D+N+ P ST V V E G + + D D G N+ V+ + + F + K + + +++ + + I D G S+ ++ L I E P F + ++ E+ + +++AT + IRY++ G ++D SG + LD E+ A D + T I + + D NDNAP+ +I V E +LI + A+D D G+N V + L + + F +++ G I T LDRE Y V D+G M + +V + +LD+NDN P++ + N+T V+ V + D D G N Y + P K F ++ SG I + LD +Q + L ++ASD A
Sbjct: 2312 RIRYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYS------LTVRAEDCALENPAGDTAE-LTIN--ILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSG---DIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEH----MHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFD--STTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSS-KAELTVILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAI--AGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRL------QNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLFSL----NVTENAEIGSFVIRVTSSDLDLGANANASYSF-SENPGEK---FRIEPQSGNITVAGHLDREQQDEYILKVVASDGA 2992 HSP 7 Score: 146.362 bits (368), Expect = 5.837e-35 Identity = 174/693 (25.11%), Postives = 300/693 (43.29%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI--DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSG-------------------SPPK--STDRSVLVH---------------ITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEK-----GKA---FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPE---FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKG-KYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGE-NGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKP 2365
V + + D ND+ P F + E L + +++S A D D + ++ KF L+ S L L LD ET+ +Y L ++ D T+ I V D NDN P+F Y I EN G V + A D D G + Y + D ND+ F +N +G + L RL + + Y V A+D+ P + V V D+N+ P+ +S + EV EN + ++T+ D D G N + + T +D + ++ + R+ D E + ++ D SP K T + L H I D+N+ P F E ++ EN A NT V+ + A D D I Y + E G++ F ++ G ++ + LDRE+ + + N A D P + +++++ I DENDN+P+F P+ +V EN ++ +++ATD D+G N ++ + ++ + FS+S++ G + ++L+ E Y+L V D + P + +T+ +LD NDN+P +++ +P + V+TV A+D D N +++Y + + +F ++ SG+I L+K LD +Q LT++A D+ + P
Sbjct: 1809 VRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPD--TLGSVTFLLMDGHDGKFLLEPSTG---KLILNDTLDRETKSKYELRIRVSDGVQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDV-----FSLNPQTGMLTLTARLDYEEVQHYILIVQAQDN--GQPSLSTTITVYCNVLDLNDNAPIFDPMSYSS--EVFENVPIATEVVTVSAKDIDSGNNGLIEYSI-TAGDVDSEFGIDSNG--TIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFIS-ANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVD-ALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFD--PKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLG-----DQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLD-SPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSD----LFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPP 2470 HSP 8 Score: 146.362 bits (368), Expect = 7.598e-35 Identity = 203/826 (24.58%), Postives = 346/826 (41.89%), Query Frame = 2
Query: 113 PKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFI-------------GNIKYAL-PDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFI---DSLTVNLQINDLNDNTPLF---------STIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQISLRLKSELDYETRKQYRLTLKACD---RDSCTDK--ELIIDVQDENDNKPIFTKNFYKVSILE------NTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE-----KVPVEITVEDINNYYPVIAILSTNE-RVEVRENTLPGNLITI-KVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYS---LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYT----------------------LEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAF--DTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATK 2362
PKF+ + +I+ + + + N+T+ E+ P + G++ +AL P + L+F +D+ G +T ++ +D E + Q + V+ D+ + TV L + D+NDN P F + + I L++ + + +A D+D +N + Y+LE F+LD ++ ISLR + + Y+L + A D R S D E+++ + E Y+ ++E N+ V V + + Y+I D Q F I++ SG I R L ++ Y ++A S ++ + V I + D+N+ PV A+ +E + + EN G I + +V D D G+NS+++ L F++ LY +R+ E G + + TD+GSPP S+ S+ V I D+N+++P F YE SL E T NT+ L ATD D + R S ++ + F + G++ + LDRE + DA ++ +++ + DENDNAP F F++ EN + +G+LTA D D G N+++ F L + Q ++ GFI+TL+ DRE + LE V D G + V V V D NDN P+++ Y++T +E F D D G NG + Y + ++ F+LD +G++ L + LD + E L ++A D+A K
Sbjct: 578 PKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDAL------TGQLTTRRPLDREKMSQ------------YEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKD-DGDNALIEYRLESGGEGLFQLD-ARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQG---DRAQNFRIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRA---EPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGV-FPDGYLFVR-APLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTL------SSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFL-----RAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAK---GNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALK 1361 HSP 9 Score: 145.976 bits (367), Expect = 8.415e-35 Identity = 187/759 (24.64%), Postives = 334/759 (44.01%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQF---LQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL-EDSSNKFELDTSKFPQIS-LRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKD-SGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLER--RLAANQ-----RKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVE----VRENTLPGNLITIKVSDN---DIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSAS----------IKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT--VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYP---MATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIA 2344
N V EE P Q I +K + D ++ + + + F +I ++G++ + R+D E + G + ++ + + +V L + D NDN P F+ + ++ + E+ + + ++ D D A N SY E+ KF ++ PQ + + LD E + +Y L + A D + + I +QD+NDN P F +FY S E + +LV + A D+D G ++ Y++ P+ + F I+ +GE+ ++ R +Q +Y V+A D+ P + V I + D +N P E+ E + ++ + G I ++V N D+G N ++D+ L+ NL S+ SV D VK ++ TD G PP+S + V++ +T N +P F Y+V + EN + +L + ATD D +RYS+ + F +D +G I + LD ++I+ N D P ++ + + + D NDN P+F E+ + EN + + A D D N+ + + L + + F +++ G I + S D E YTL++ K K P M + N+ V VL N+ PQ++ P ++++ V VQA D D+GE+GR+ Y + +S F +D ++G I + + LD + ++ LT++A
Sbjct: 2816 NAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEITESGEIYTRMRLDREEI--------GDYAFVVE--AVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLF-SLNVTENAEIGSFVIRVTSSDLDLGA-NANASYSFSENPGEKFRIE----PQSGNITVAGHLDREQQDEYILKVVASDGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPM-----FSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNG-KPPLYSECLVNINIVDAHNNPPKF------EQAEYLAPLPQDAVRGQRI-VRVHANDKQDLGTN-----------EMDYSLMTF--NLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQ-QLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFN-HKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRH----FFIMNQSNGTISSAVSFDYEERRIYTLQI----KAKNPDSSMESYANLYVHVLGVNEFYPQFLQP---VFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVG---SSNDKGFRIDTNTGLIYVARHLDRETQNRVVLTVMA 3516 HSP 10 Score: 141.739 bits (356), Expect = 1.623e-33 Identity = 148/570 (25.96%), Postives = 258/570 (45.26%), Query Frame = 2
Query: 722 QYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRY------SLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFA--HDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDAD-KGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNE----LVMTVQAFDTDAGENGR-IKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPK 2368
+Y L ++A DR + ++I V EN + P F+ N Y+V + EN GS ++TV A D D+G G++ Y+I N+ Q F ++ +G I ++++L + + Y ++ +D + +P + I + D+N+ PV + EN G + +D D N+ ++ S D ++ +++S SFD+E ++ + IK + S +S ++ VH+ +NE+ P+F Q ++ + E +A T+V + ATD+D R S ++KG F+ID +G I LDRE +V A + + T ++I++I+D ND T+ E + + A D D + N+Q + ++ +++ F + + G I T LDRE +Y L +G D G P S V +++ D NDN P + PE + I++NE +MT+ A D D NG Y++ K S S+D +SG +R D + + II + + KPK
Sbjct: 3194 RYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNER---QDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGY-HPLSSVAMLTIILTDVNDNPPVFN--HKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAF-LPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSSMESY-ANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKG---FRIDTNTGLIYVAR-HLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDPPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIING-----NLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTF------TPE-GLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSW---LSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPK 3736 HSP 11 Score: 134.42 bits (337), Expect = 3.197e-31 Identity = 188/773 (24.32%), Postives = 333/773 (43.08%), Query Frame = 2
Query: 188 TANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQ---FLQINDNGDVTLKKRIDLETLCQNS-------------NICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIE-SYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD----RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKE-----NLYSLASVRSFDFESGQVKSASIKCTDSGSPPK---STDRSVLVHITDMNEYSPEFKQL---IYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKAFFKIDHMSGWIK-TKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMIST----RLIGRLTATDADKGNNSQVEFVLLKTLA--RKQEVQKIFSV-SKEGFIETLQSLDRETF-ESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI---HNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDS 2353
T ++ E + F+G + D + + L F + SQ F NG + + D E L + S G ++ ++ V N D + V + + D+NDN P F +T+ E ++ D D + S + + +F LD++ L L LD E+++ + L + A D ++ + I V DENDN P FT++ +VS+LE + TG+ ++ A D D G V+++I A N D TF I+S +G + L + L YT ++ A SD P V + V D N+ P+ ST +++E L ++T+ D D G+N KV+ + SK + QL + + + ++R D ES ++ TD P + ST++ V V + D+N+ +P F + I + ++T V+Q++A D D +++ + Y + + FK+ +G I T +EV + + D V ++++ +TI V P+F + + + IG T ++++E+ + A + +V ++F + +K G + T LDRE E Y +EV G P + T V V VLD+ND+ PQ+++ + YN++ + + T++A D D G + + + H+ K F L+ +G++ L LD + + EL I SD
Sbjct: 1157 TFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYM-LLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATG---QLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRD---TFHIDSITGSLYLHKPLDYEDITSYTLNITA--SDCGTPSLSTTVLYNVLVVDDNDNPPIFP--STAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAI---SKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKST--DEAVQSERRSSEVYITIITPGSGGSESSV-PQFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFV---YNVSEDLQIGHTISTLRAHDPDT--LGSVTFLLMDGHDGK-------FLLEPSTGKLILNDTLDRETKSKYELRIRVSDG 1900 HSP 12 Score: 133.65 bits (335), Expect = 5.458e-31 Identity = 157/590 (26.61%), Postives = 256/590 (43.39%), Query Frame = 2
Query: 701 LDYETRKQYRLTLKACDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS---IRYSLDEKGKAFFKIDHMSGWIKTKNVV------LDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNE----LVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKP--KMVMLKLIINN 2398
LDYE Y + ++A D D+ + + + ++V D NDN P+ + Y +LE L+ V A D+DSGD G V+Y + ND D TF I + SGEI RL + Y F V A D + V + + D N+ P L + + V EN G+ +I + SD D+G N+ + F++ + N + D E + +D + + + I D N+ +PEF+ Y S E + V Q+ ATDRD I YSL ++ F ID +G + +K V R A D P + + + I D ++N P F + ++ + + I R+ A D +++++ L+ + IFSV + +G+I ++ + Y L V D+G P + T V + V EN + P++ +N Y + I+ +NE ++TV A D D G NG ++Y I N +Q FS+DE +G I + ++LD+D I+ L I D P + ML +I+ +
Sbjct: 2768 LDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQ--NDFD--GTFEI-TESGEIYTRMRLDREEIGDYAFVVEAVDQGVPH-MTGTASVLLHLLDKNDNPPKFTRLFS---LNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGN---ITVAGHLDREQQDEYILKVVASDGA---WRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSL-QQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTF-----NLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFS----VN-SYQV--IVPENEPVGSTILTVGATDDDTGPNGMLRYSISG--GNERQD-FSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTD 3326 HSP 13 Score: 129.798 bits (325), Expect = 8.245e-30 Identity = 167/663 (25.19%), Postives = 285/663 (42.99%), Query Frame = 2
Query: 467 NLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS------SNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKEL------IIDVQDENDNKPIFTKNFYKVSILE---NTDTGS--LVVTVNAYDKDSGDLGLVMYNI-DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVE----VRENTLPGNLI---TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESG-QVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDA--YVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQS-LDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSA 2356
N+ + D NDN P+F + ++E +P+ + +A D D ++ SY + F ++T +LR E+D E+ +RLT+ A DR ++++L + V+D NDN P+F +IL +T GS V+ V+A D DS GLV Y I P +L F + N+G I Q Y + + D + ++ V IT+ + ++ +R + V EN G I T ++ +I + ++D +L L L++ D E+G + + G P+++ V V + D N+ P+F + ++ E+ + L A D D S+ + L + F ++ +G + N LDRE D Y + + + + D NDN P+F + F + EN +G++ A DAD G N+Q+ + ++ A +FS++ + + TL + LD E + Y L V +D G+ ++T+ V VLD NDN P + +P++ + + V+TV A D D+G NG I+Y I +S+ F +D + G IR + LD + LT+ A D A
Sbjct: 1476 NVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKV-SYAISKQEPQLPQGRHFGINTETGVIHTLR---EIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVS--MNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQEL-----FKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQS-ERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVD-RLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLLMDGHDGKFLLEPSTGKL-ILNDTLDRETKSKYELRIRVSDGVQYTEAYAT-----IQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWA-----NDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIF---DPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSE---FGIDSN-GTIRTRRNLDREHRSTYTLTVTARDCA 2107 HSP 14 Score: 114.005 bits (284), Expect = 4.721e-25 Identity = 161/629 (25.60%), Postives = 262/629 (41.65%), Query Frame = 2
Query: 260 DKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRN--DFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK--FELDTSKFPQISLRLKSELDYETRKQYRLTLKACD---RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGS-PPKSTDRS-VLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS---IRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT---VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDN 2092
+++ +S + FN+ S F +G +TL K I + + + V DR D V + + N +TP FS + + E+ PV ++ A D D + N + Y + + + F +D + ++ +LDY+ ++Y L + D + L I + D NDN P+F Y I EN G+ V +A DKDS ++ Y P+ D F +N ++G I +R++YT + AK+ D + + + + V +N +YP L +V E + G + ++ +D D G + +V L S + L +A R D E+ ++ + GS TD + V++ I D N+ PEF + Y ++ E TKV + A D+D YS+ + K FKID +G I T + LDRE T A D + P T + + + +ED NDN P F PE + EN + I L A+D D N + + K + SV + G + + S DRE + V D GK + +T+ VLD+NDN
Sbjct: 3157 NEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTR------------YELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDD-TGPNGMLRYSISGGNERQDFSVDERTG---GIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAF-LPSGPDR-HFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPD--SSMESYANLYVHVLGVNEFYP--QFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLIYVA--RHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASR-LDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTF--TPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGP--FTYQLIGGKH--KSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDN 3753 HSP 15 Score: 96.6709 bits (239), Expect = 1.105e-19 Identity = 126/467 (26.98%), Postives = 193/467 (41.33%), Query Frame = 2
Query: 1097 VPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKID--FQLLKKKE-----NLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKT--------KNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI--FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQ--VEFVLLKTLA--RKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN--ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIASDSATKPKMV--MLKLII 2392
+ V I V D+N+ P S + E+ G L+ +D D+G N + +D F+L+ + L + + D ES +I D GSPP+ V V I D+N+ P F Y VSL E T V+ + A+D D + I Y L E + F ++ +G I T + V ++ VF FA D T + V + D ND+ PI F P+ TV EN ++ ++ + D+D G N + V V L R +E + V G LDRE Y L V D+G T+ ++ + V D ND++P + EY+ ++ + V ++ A D D G N ++ Y I + ++ FS+D +G I LD D +EL+I A D PK LK+II
Sbjct: 140 IEVRIKVLDVNDNSPEFPEPSI--AISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAET-EHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGV------LDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKS-----EYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILS---GNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVII 589 HSP 16 Score: 80.4925 bits (197), Expect = 8.692e-15 Identity = 103/368 (27.99%), Postives = 158/368 (42.93%), Query Frame = 2
Query: 533 LRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSN--KFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD----RDSCTDK-ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKD-SGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKE--------NLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSL-RENTATNTKVLQLNATDRDGAASIRYSL 1582
+ E+ V + A D+D + R+ Y L SSN F +DT+ + + LD ET+ + LT+ A + R + TD+ ++II +QD ND P F K++Y +I E G+ V TV A DKD Y+I N L Q+F I+ +GEI RL + Y + A D+ PQ V I +ED+N+ P N + EN G +++T+ SD D+ N +QL+ K N + S SFD E + A I+ DSG P + + + + + D N+ + L VSL + +N K+ + D D R L
Sbjct: 3448 VSETSAVGTRVGAVQATDKDSGEDGRV-YYLLVGSSNDKGFRIDTNTG---LIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGN---LKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLP-PQTGSATVHIELEDVNDNGPTFTPEGLNGYIS--ENEPAGTSIMTLIASDPDLPRNG---------GPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDNPSTTRSLHIAVSLFNGDLPSNVKLADVRPNDIDIVGDYRCRL 3795
BLAST of Protocadherin vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 204.142 bits (518), Expect = 7.695e-53 Identity = 199/696 (28.59%), Postives = 313/696 (44.97%), Query Frame = 2
Query: 326 GDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAEN---------------RIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELI---IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI--LSTNERVEVRENTLPGNLIT-IKVSDNDIGMN-SKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA---FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-------RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVK 2305
G++ K ++D ET S + + ++ RN + V + + D NDN P F I E+ P +L A D D N R+ S++ D +L S F LD ET Y L ++A D + + + I +QD NDN+PIF ++ Y ++ EN G+ V+ V A D D+ + GLV Y I+ D Q F I+ +G I + + L ++L+ VVAKD P + V I V D+N+ P I + LS + ++ E+ PG + I V D D + VN L F L + ++Y + D E + S+ TD G+PP +S+ + ITD+N+ PEF+Q +Y ++ E T VLQ+ A DRD +++ YSL E + +F+ID +G I T++ + D E A D V P ++T ++VTI D NDN PIF +V EN R I +++A+D D G N+ V + + + E F V S G I LD E SY V D+G ++T+ + +++ D NDN+P + P EY ++ + ++ V A D D G G++ YRI ++ +F +D +GEI +V+
Sbjct: 130 GEIRTKVKLDRETRASYSLVA-----------IPLSGRN-----IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGF----------LDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINR-RQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHG-EQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDG-HFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHI-DCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTE----FEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVFY-PR----EYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRI---VAGNEAGIFRIDRSTGEIFVVR 781 HSP 2 Score: 202.216 bits (513), Expect = 2.966e-52 Identity = 200/724 (27.62%), Postives = 316/724 (43.65%), Query Frame = 2
Query: 338 LKKRIDLETLCQNSNICCGQFLCF-----IQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLES-----AFDRDFSAENRIESYKL--EDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG-------------KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINK---NELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKPK--MVMLKL 2386
K + E + IC L F + VL DR + + +Q+ D+NDN P+F E ++LRES + S A D D+ ++ SY++ + + F +D S +R L T+ + L + A D S D + + + D PIF K Y + E+ G++V +V A D V Y+I + D D F I +NSG IR+ + L + ++ A + P V I VED+N+ P ++ R+ V E+ L L D D G + +V L ES + + L+ + D+ES Q + + TD G P ST+ ++LV + D+N+ P F++ Y V++ E+ + N +++Q+NA+D D A I Y + + G F I SGWI + LDRE + A D A T++IV + D NDN P F EF ++EN+ ++G +TA+D D G N+ + + LL + F V G I T + LDRE E Y L V RD+G + V + V D NDN P+ +P+ ++ + + V+ V+A D D G+N I Y I + + +FS+D SG IR LD ++ L + ASD P+ + ML++
Sbjct: 654 FKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQV-SYRIVAGNEAGIFRIDRSTGEIFVVR-PDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYS-GDPD--GYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGE--PPVYGHTQVNIEVEDVNDNAPEFE--ASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS--QHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLR-APLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLP-------INSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIA-----DPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRV 1353 HSP 3 Score: 198.364 bits (503), Expect = 4.545e-51 Identity = 196/706 (27.76%), Postives = 318/706 (45.04%), Query Frame = 2
Query: 368 CQNSNICCGQFLCFIQTK---VLVNDRNDFIDSLTVNLQI----NDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLED----------SSNKFELDTSKFPQIS-LRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNP-QKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRS-FDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKG-----------------KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHD--AYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQK----IFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGK---YPMATSTNVTVKVLDENDNKPQWMNPNPINPE------YNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
++ ++ Q L + ++ ++V + + SL+ NL I D+NDN P+F E ++ + ES +N + +A D D RI +Y++ D SS+ FP + L++ LD ETR +Y+LT+ A D + +I+ V D NDN P F K+ Y+ I EN GS+V V A D D G+ + Y++ L + +F ++ +GEI L R+LY V A+D P + +VPV I V D+N+ P IA + V VRE PG ++ ++ D D G N+ + + D L + + R D E + + +D G+PP+ T R + V + D+N+ P F +RE+ A V ++ +R A +R S++E +A F ID SG + +LDREV A D A +P ++ + + + D NDNAP + P + V E +I TATDAD G N +++ L++ + E Q+ +F + S G + LD E + Y L V D+ + TS V +++LD ND+ P +++PN + + TRI E+V + A D D+G+NG++ Y I + F ++ +G I LVK L
Sbjct: 983 ARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARI-TYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSL-----LPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQ--GTPVRSARVPVRIHVSDVNDNAPEIAD-PQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERP-ADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVAR-LLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRI---GEVVAHIVAVDEDSGDNGQLTYEITGGNGEGR---FRINSQTGIIELVKSL 1671 HSP 4 Score: 162.925 bits (411), Expect = 4.952e-40 Identity = 176/717 (24.55%), Postives = 317/717 (44.21%), Query Frame = 2
Query: 452 DSLTVNLQINDLNDNTPLF--STIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEI----RLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERV----EVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSP--EFKQLIYEVSLRENTATNTKVLQLNATDRDG-AASIRYSLDEKGK-AFFKIDHMSGWIKT-KNVVLDREVIETIVFNAFAHDAYVD-------------------------------------------------PFTAT-TKIIVTIEDENDNAPIFGVIPEF--TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSATKPKMVM 2377
D T+ + + D+NDN+P F + S P + S D +A+ I S + NKF +D+S ++S R LD E +Y L ++A DR ++ + I V+D+NDN P F + Y S+ E+ G+ VV ++A D D G ++Y++ F I+ SG I +L+R L A+ Y F V+A D + VPV+I V DIN+ P+ ER +V PG L+ ++ D D+G N+++ L E+ + + +L++ +S ESG++ + D G+PP+S+ + + I + + +P F+ Y V L+EN+ + T++LQ+ A DG +++S + +D +SG I+ K +LD + T +A + + PF A+ ++++ +EDENDN+P F +F TV E + ++ A D+D G+N+++ + ++ + + + G + T LDRE + Y L++ D+G M + + V+++D NDN+P + P N ++ ++ ++ A D D + + +F+LD SG++ L + LD++ + EL +IASD+A + + V+
Sbjct: 1829 DVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNAD-LIYSITGGNLGNKFSIDSSSG-ELSAR---PLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQ----FAIDGQSGLITTVGKLDRELQAS----YNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIF------ERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQ-KQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDG---NHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTF----PPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVL 2518 HSP 5 Score: 121.709 bits (304), Expect = 2.001e-27 Identity = 175/670 (26.12%), Postives = 289/670 (43.13%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLF----STIEQTITL--RESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKS----ELDYETRKQYRLTLKACDRDSCTDKE----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQT---FGINSNSGEIRLERRLA---------ANQRKLYTFHVVAKD------SDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKID-FQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDR-SVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIR--YSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHD-AYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMIS-TRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINK-----NELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKE--LDFDQ 2323
S+TV L+I D ND+ P F S+ +T +L ++ + ++ A D D S +N +Y++ + + + I +KS D E ++ L + A D K+ L + VQ ++N P F + Y+ +ILEN +GS V+ V A + + Y I A DL GI + G+ E + + AN++ + V K D +N Q V + ITV D+N+ P S + V EN+ PG + T+ SD D G N+ + + + + F + L S R D E + I+ +D G P ++ + + D N+ +P FK Y S++E+ T V+Q++A D D + R YSL + + F ID SG I T LDRE+ + F A D + +AT + + + D NDN PIF P +I + + ++ A DAD G N+++ + L A V F ++ G + QSL E+ + LEV RDKG P ++ + + + + P N R++ K ++ V A +D G ++++ ++ + SLD SGEIR+ K LD+D+
Sbjct: 1585 SVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDED-SGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYG-LSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGEL----SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVG-KLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSL---NAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQN------ETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSF---GAGNEDGILSLDSLSGEIRVNKPHLLDYDR 2234 HSP 6 Score: 120.168 bits (300), Expect = 7.075e-27 Identity = 159/657 (24.20%), Postives = 268/657 (40.79%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQ----DENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYP-------------------------VIAILSTNERVEVRENTLPGN---LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLY---------------SLASVRSFDFESGQVKSAS-------IKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGK--AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEY--------NITRIINKNELVMTVQAFDTDA-GENGRIKYRI 2230
+ + + D NDN P F + T +++E P+ S+ SA D D R+ ++ +F +D ++ +LD E + Y + A D + + VQ D NDN+PIF + Y + G ++ V A D D G ++Y+++A N + F IN ++G + + LA+ KL VVA+D N PQ +E+ + + P V+A+ S R +V+ + GN ++++ +I +N + S L + L+ S S R+ S + ++ + + +P ++ +++ + D N+ SP+F Q + ++ E T V Q++A D D A +RY + + AF SG ++T N+VLDRE+ + A D V T T I V I D NDN P F TV E +I ++A D D + + L E IF++ + G + + LD E + Y L+V D T +TV+V DENDN P ++ P P Y I+ ++ + ++TV A D D+ G N ++ Y I
Sbjct: 1938 ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTV---GKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSA-VSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKG-NPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRT-NIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVD--TYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAH---EARTVLTVRVNDENDNAPVFLAQQP--PAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYII 2581 HSP 7 Score: 93.5893 bits (231), Expect = 9.250e-19 Identity = 156/680 (22.94%), Postives = 291/680 (42.79%), Query Frame = 2
Query: 419 KVLVNDRN--DFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRD--------FSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKN----FYKV--SILENTDTGSL---VVTVNAYDKDS-GDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLE-RRL--AANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPP------KSTDRSVLVHITDMNEYSPEF-KQLIYEVSLRENTATNTKVLQLNATDRDGA----ASIRYSLDEKG-KAFFKIDHMSGWIKTKNVV---LDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT--VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDE-----NDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD 2320
K++ D + T+ +QI D+NDN P F +T+ E+ + ++ SA D D AE+ ++ +E+ S F LD L LK LDYE +++Y L + A D L + V DENDN P+F ++ + +I E +++ S+ ++TVNA D DS G+ V+Y I+ + F ++ ++G + + RL A + Y ++AKD+ K + V+ +N L R ++ E G+++ +++ + + + + + + F+LL+ K ++ V+ D E + + + PP S+ SV++ I D N+ P F + YE + E + QL A D D + + Y + + F ID ++G + N + + E I+ +H + P + + + DENDN P F + E+ + EN + R A+D DKG Q+ + + + K+F V S+ G + + D E + Y +E+ D G + + V ++ DE + +++ P + + + +V V A D+D+G +GR+ Y++ P + F ++ SG + + ++L D
Sbjct: 2397 KIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPP-NNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVD---IENMS-IFALDRYSG---KLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQ-----EGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDA---GKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVV-LQLGQDALDQSLAI---IAGNEESAFELLQSK----AIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSH--HQRPLCSLQPFRLELHDENDNEPKFPLT-EYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYS-IGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAV--------ALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSH-----FKVNRSSGAVLIKRKLKLD 3035
BLAST of Protocadherin vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 204.142 bits (518), Expect = 7.695e-53 Identity = 199/696 (28.59%), Postives = 313/696 (44.97%), Query Frame = 2
Query: 326 GDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAEN---------------RIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELI---IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI--LSTNERVEVRENTLPGNLIT-IKVSDNDIGMN-SKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA---FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-------RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVK 2305
G++ K ++D ET S + + ++ RN + V + + D NDN P F I E+ P +L A D D N R+ S++ D +L S F LD ET Y L ++A D + + + I +QD NDN+PIF ++ Y ++ EN G+ V+ V A D D+ + GLV Y I+ D Q F I+ +G I + + L ++L+ VVAKD P + V I V D+N+ P I + LS + ++ E+ PG + I V D D + VN L F L + ++Y + D E + S+ TD G+PP +S+ + ITD+N+ PEF+Q +Y ++ E T VLQ+ A DRD +++ YSL E + +F+ID +G I T++ + D E A D V P ++T ++VTI D NDN PIF +V EN R I +++A+D D G N+ V + + + E F V S G I LD E SY V D+G ++T+ + +++ D NDN+P + P EY ++ + ++ V A D D G G++ YRI ++ +F +D +GEI +V+
Sbjct: 130 GEIRTKVKLDRETRASYSLVA-----------IPLSGRN-----IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGF----------LDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINR-RQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHG-EQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDG-HFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHI-DCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTE----FEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVFY-PR----EYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRI---VAGNEAGIFRIDRSTGEIFVVR 781 HSP 2 Score: 202.216 bits (513), Expect = 2.966e-52 Identity = 200/724 (27.62%), Postives = 316/724 (43.65%), Query Frame = 2
Query: 338 LKKRIDLETLCQNSNICCGQFLCF-----IQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLES-----AFDRDFSAENRIESYKL--EDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG-------------KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINK---NELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKPK--MVMLKL 2386
K + E + IC L F + VL DR + + +Q+ D+NDN P+F E ++LRES + S A D D+ ++ SY++ + + F +D S +R L T+ + L + A D S D + + + D PIF K Y + E+ G++V +V A D V Y+I + D D F I +NSG IR+ + L + ++ A + P V I VED+N+ P ++ R+ V E+ L L D D G + +V L ES + + L+ + D+ES Q + + TD G P ST+ ++LV + D+N+ P F++ Y V++ E+ + N +++Q+NA+D D A I Y + + G F I SGWI + LDRE + A D A T++IV + D NDN P F EF ++EN+ ++G +TA+D D G N+ + + LL + F V G I T + LDRE E Y L V RD+G + V + V D NDN P+ +P+ ++ + + V+ V+A D D G+N I Y I + + +FS+D SG IR LD ++ L + ASD P+ + ML++
Sbjct: 654 FKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQV-SYRIVAGNEAGIFRIDRSTGEIFVVR-PDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYS-GDPD--GYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGE--PPVYGHTQVNIEVEDVNDNAPEFE--ASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS--QHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLR-APLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLP-------INSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIA-----DPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRV 1353 HSP 3 Score: 198.364 bits (503), Expect = 4.545e-51 Identity = 196/706 (27.76%), Postives = 318/706 (45.04%), Query Frame = 2
Query: 368 CQNSNICCGQFLCFIQTK---VLVNDRNDFIDSLTVNLQI----NDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLED----------SSNKFELDTSKFPQIS-LRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNP-QKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRS-FDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKG-----------------KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHD--AYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQK----IFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGK---YPMATSTNVTVKVLDENDNKPQWMNPNPINPE------YNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
++ ++ Q L + ++ ++V + + SL+ NL I D+NDN P+F E ++ + ES +N + +A D D RI +Y++ D SS+ FP + L++ LD ETR +Y+LT+ A D + +I+ V D NDN P F K+ Y+ I EN GS+V V A D D G+ + Y++ L + +F ++ +GEI L R+LY V A+D P + +VPV I V D+N+ P IA + V VRE PG ++ ++ D D G N+ + + D L + + R D E + + +D G+PP+ T R + V + D+N+ P F +RE+ A V ++ +R A +R S++E +A F ID SG + +LDREV A D A +P ++ + + + D NDNAP + P + V E +I TATDAD G N +++ L++ + E Q+ +F + S G + LD E + Y L V D+ + TS V +++LD ND+ P +++PN + + TRI E+V + A D D+G+NG++ Y I + F ++ +G I LVK L
Sbjct: 983 ARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARI-TYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSL-----LPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQ--GTPVRSARVPVRIHVSDVNDNAPEIAD-PQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERP-ADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVAR-LLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRI---GEVVAHIVAVDEDSGDNGQLTYEITGGNGEGR---FRINSQTGIIELVKSL 1671 HSP 4 Score: 162.925 bits (411), Expect = 4.952e-40 Identity = 176/717 (24.55%), Postives = 317/717 (44.21%), Query Frame = 2
Query: 452 DSLTVNLQINDLNDNTPLF--STIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEI----RLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERV----EVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSP--EFKQLIYEVSLRENTATNTKVLQLNATDRDG-AASIRYSLDEKGK-AFFKIDHMSGWIKT-KNVVLDREVIETIVFNAFAHDAYVD-------------------------------------------------PFTAT-TKIIVTIEDENDNAPIFGVIPEF--TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSATKPKMVM 2377
D T+ + + D+NDN+P F + S P + S D +A+ I S + NKF +D+S ++S R LD E +Y L ++A DR ++ + I V+D+NDN P F + Y S+ E+ G+ VV ++A D D G ++Y++ F I+ SG I +L+R L A+ Y F V+A D + VPV+I V DIN+ P+ ER +V PG L+ ++ D D+G N+++ L E+ + + +L++ +S ESG++ + D G+PP+S+ + + I + + +P F+ Y V L+EN+ + T++LQ+ A DG +++S + +D +SG I+ K +LD + T +A + + PF A+ ++++ +EDENDN+P F +F TV E + ++ A D+D G+N+++ + ++ + + + G + T LDRE + Y L++ D+G M + + V+++D NDN+P + P N ++ ++ ++ A D D + + +F+LD SG++ L + LD++ + EL +IASD+A + + V+
Sbjct: 1829 DVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNAD-LIYSITGGNLGNKFSIDSSSG-ELSAR---PLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQ----FAIDGQSGLITTVGKLDRELQAS----YNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIF------ERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQ-KQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDG---NHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTF----PPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVL 2518 HSP 5 Score: 121.709 bits (304), Expect = 2.001e-27 Identity = 175/670 (26.12%), Postives = 289/670 (43.13%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLF----STIEQTITL--RESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKS----ELDYETRKQYRLTLKACDRDSCTDKE----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQT---FGINSNSGEIRLERRLA---------ANQRKLYTFHVVAKD------SDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKID-FQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDR-SVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIR--YSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHD-AYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMIS-TRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINK-----NELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKE--LDFDQ 2323
S+TV L+I D ND+ P F S+ +T +L ++ + ++ A D D S +N +Y++ + + + I +KS D E ++ L + A D K+ L + VQ ++N P F + Y+ +ILEN +GS V+ V A + + Y I A DL GI + G+ E + + AN++ + V K D +N Q V + ITV D+N+ P S + V EN+ PG + T+ SD D G N+ + + + + F + L S R D E + I+ +D G P ++ + + D N+ +P FK Y S++E+ T V+Q++A D D + R YSL + + F ID SG I T LDRE+ + F A D + +AT + + + D NDN PIF P +I + + ++ A DAD G N+++ + L A V F ++ G + QSL E+ + LEV RDKG P ++ + + + + P N R++ K ++ V A +D G ++++ ++ + SLD SGEIR+ K LD+D+
Sbjct: 1585 SVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDED-SGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYG-LSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGEL----SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVG-KLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSL---NAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQN------ETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSF---GAGNEDGILSLDSLSGEIRVNKPHLLDYDR 2234 HSP 6 Score: 120.168 bits (300), Expect = 7.075e-27 Identity = 159/657 (24.20%), Postives = 268/657 (40.79%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQ----DENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYP-------------------------VIAILSTNERVEVRENTLPGN---LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLY---------------SLASVRSFDFESGQVKSAS-------IKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGK--AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEY--------NITRIINKNELVMTVQAFDTDA-GENGRIKYRI 2230
+ + + D NDN P F + T +++E P+ S+ SA D D R+ ++ +F +D ++ +LD E + Y + A D + + VQ D NDN+PIF + Y + G ++ V A D D G ++Y+++A N + F IN ++G + + LA+ KL VVA+D N PQ +E+ + + P V+A+ S R +V+ + GN ++++ +I +N + S L + L+ S S R+ S + ++ + + +P ++ +++ + D N+ SP+F Q + ++ E T V Q++A D D A +RY + + AF SG ++T N+VLDRE+ + A D V T T I V I D NDN P F TV E +I ++A D D + + L E IF++ + G + + LD E + Y L+V D T +TV+V DENDN P ++ P P Y I+ ++ + ++TV A D D+ G N ++ Y I
Sbjct: 1938 ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTV---GKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSA-VSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKG-NPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRT-NIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVD--TYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAH---EARTVLTVRVNDENDNAPVFLAQQP--PAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYII 2581 HSP 7 Score: 93.5893 bits (231), Expect = 9.250e-19 Identity = 156/680 (22.94%), Postives = 291/680 (42.79%), Query Frame = 2
Query: 419 KVLVNDRN--DFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRD--------FSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKN----FYKV--SILENTDTGSL---VVTVNAYDKDS-GDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLE-RRL--AANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPP------KSTDRSVLVHITDMNEYSPEF-KQLIYEVSLRENTATNTKVLQLNATDRDGA----ASIRYSLDEKG-KAFFKIDHMSGWIKTKNVV---LDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT--VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDE-----NDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD 2320
K++ D + T+ +QI D+NDN P F +T+ E+ + ++ SA D D AE+ ++ +E+ S F LD L LK LDYE +++Y L + A D L + V DENDN P+F ++ + +I E +++ S+ ++TVNA D DS G+ V+Y I+ + F ++ ++G + + RL A + Y ++AKD+ K + V+ +N L R ++ E G+++ +++ + + + + + + F+LL+ K ++ V+ D E + + + PP S+ SV++ I D N+ P F + YE + E + QL A D D + + Y + + F ID ++G + N + + E I+ +H + P + + + DENDN P F + E+ + EN + R A+D DKG Q+ + + + K+F V S+ G + + D E + Y +E+ D G + + V ++ DE + +++ P + + + +V V A D+D+G +GR+ Y++ P + F ++ SG + + ++L D
Sbjct: 2397 KIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPP-NNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVD---IENMS-IFALDRYSG---KLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQ-----EGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDA---GKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVV-LQLGQDALDQSLAI---IAGNEESAFELLQSK----AIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSH--HQRPLCSLQPFRLELHDENDNEPKFPLT-EYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYS-IGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAV--------ALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSH-----FKVNRSSGAVLIKRKLKLD 3035
BLAST of Protocadherin vs. Ensembl Fly
Match: kug (gene:FBgn0261574 transcript:FBtr0332722) HSP 1 Score: 196.823 bits (499), Expect = 1.744e-50 Identity = 175/644 (27.17%), Postives = 300/644 (46.58%), Query Frame = 2
Query: 488 NDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSS--NKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERV-EVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNE--YSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA---ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEF-VLLKTLARKQEVQKIFSVSKEGFIETLQ-SLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD-QIELTIIASDSATKPK 2368
N + P F Q +++ ES+ + +++ A DRD ++ + + D + F +D + L++ LD E + +Y L + D + T K L I + D NDN+P+ K + E+ G++V ++A D DSG V Y + F +N+ +G +RL + L ++ Y H+ AKD E + V + V+D+N+ PV + E + +VRE+ G L I+ D DIG N+++ L+ E++ D +L + ++ ++ + D+E+ QV + + D G P ++D S+++ I D+NE ++PEF +YE ++EN T V+ + A D D + I YS+ G F ++ LD E A D + P + ++ + +E+ENDN P+ + V E + I L A D D + + ++ L E+ SK G I+T + LDRE + LEV + D G +++++ + V VLD NDN P++ + + + N+ + V A D+D+GENGRI Y I + K +K F +D G I + K LD D + E+ I A D+ K
Sbjct: 766 NVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKL-VFAISDGDYDSVFRIDPDRG---ELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVE-----CSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEAL-VYVLVDDVNDNAPVFGV---QEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQ-DEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQ--LDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEID-----SKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEF---DQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNK---FRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKK 1382 HSP 2 Score: 178.333 bits (451), Expect = 1.009e-44 Identity = 212/752 (28.19%), Postives = 333/752 (44.28%), Query Frame = 2
Query: 197 LTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQ--------FLQIND-NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLP---VNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTD------KELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQ-TFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE-KVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW-MNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKP 2365
+ V + NQ I +K D + S+ F + + ++IN+ GD+ K + E+ NS QF V +DR + F + V+++I + + N P F + + ES P V + + + FS + + + DS L L+ LD E ++ + L + A ++ T +++IDV+DENDN P F FY S+ EN++ +V V+A D D+G G + Y +++ D + IQ F I+ SG I L L + Y F V+A D+ +P+ + KVPV I + D N+ PV + E + V EN LPG LI + + D DI + + + FQ+ K E L + D E + SI TD K+ +V + + D+N+ +P + Y +S E+ + T ++++ A D D + +R+ L KG F I SG +K + LDRE A D ++II+T+ D NDN PIF + +V E+ LI ++ A D D G N Q+++ L+ E F +SK G I +SLDRET + L V D G + + V V +LD NDN P++ M N T V V A D G N I Y I + ++Q F +D +G++ L LD++ + LTI A D T P
Sbjct: 2661 MVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSK--AESYGVNSY----QFF------VRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIAADQDHFMISDSG-------------ELILQQTLDREQQESHNLIVVA---ETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLES--DTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADN--GHPKHDAKVPVTIKIVDYNDNAPVFKL--PIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGE----LFIAKPLDREQLMFYNLSIIATDGKFTAKA---NVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVAS-ALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMG------ENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATH----GTEVCKVYATSIDIGVNADIHYFIMS---GNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPP 3357 HSP 3 Score: 155.992 bits (393), Expect = 6.477e-38 Identity = 183/736 (24.86%), Postives = 322/736 (43.75%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPD----KLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDK---ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQT-ESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKAF--FKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKG-NNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDS 2353
L+V E P + N+ PD ++ F + + +QF QI +G++ + K +D E L F ++ D F V + + D+NDNTP I+ ES+ + ++ A D DF ++ R Y ++ F + K I L++ S LD ET +Y+L D T + E+II V D NDN PIF+ Y+VS+ E+ +L+ V+A DKD G + Y++ N F I+ ++G IRL + L ++ + F++ K D P+ + V + + DIN+ P ++ + ++ EN G + + + DIG+N+ ++ + + + F++ +L A++ D+E + +I+ D G+PP S + V + I D+N+ SP F Q +Y +++ E+ +K+L + ATD D + + Y++ E+G F ID +G I LDRE I A D + I + I D NDNAPIF ++EN + + +DAD+ N + F + R +F + ++G + T + + + ++V V D G P+ + V VK+++E+ P P+ N + V A D D + +F++ ++G+I + LD +L + SD
Sbjct: 2973 GLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQF-QIGKSGELFIAKPLDREQLM------------FYNLSIIATD-GKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRF--YLSGKGADDFSI--GKESGI-LKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENH----DYFKISKSTGIIRLHKSL--DRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYS--CKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATL---DYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNI-ERGDNIGQFSIDPKNGTISVSR-PLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDI-----RSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIV---TPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDG 3668 HSP 4 Score: 154.066 bits (388), Expect = 3.218e-37 Identity = 177/669 (26.46%), Postives = 294/669 (43.95%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNK--PIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDL-GLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYP-----VIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDE-KGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTK---IIVTIEDENDNAP-IFGVIPEFTV--KENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKPKMVMLKLIINNH 2401
V + ++D+NDN P+F E +RE LP +++ A D D I+ + L++ + EL ++R + LDYE ++ + L + A D +D ++I + D N+N+ P F Y+ + EN G+ V+ V A D D+ DL + Y+I + L + F +N + G I +L A + Y + A+D P V V I VE+ N+ P V + T VE E +IT+K D DI + + + + + + + K + R D E+ + +D+GSP S+ ++V + D+N+ SPEF Q +Y+V + + N + Q++A D D I YS+ KGK F+ID G I + E + A D + + T + ++V + + NAP I E V EN L+ ++ A D D N Q L ++ + + G I + LD ET +SY L + V D TN+ V+V+D NDN PQ+ NI+ I + ++M + A D D E+ ++ Y +H + S +F +D SG + + + LDF++ L + D K K+I+N H
Sbjct: 966 VYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQ-FSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGI---FAVN-DQGSITSLSQLDAETKNFYWLTLCAQDCAIV-PLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVE------IITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTE-RKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFE---IHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQ----LWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG---TFTAFTNLLVQVIDINDNPPQFAKD---VYHVNISENIEEESVIMQLHATDRD--EDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVH 1603 HSP 5 Score: 129.413 bits (324), Expect = 9.254e-30 Identity = 169/608 (27.80%), Postives = 273/608 (44.90%), Query Frame = 2
Query: 668 FPQISLRLKSE---LDYETRKQYRLTLKAC----DRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDS----DFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVN-CELQTESKIDFQLLKKKEN-------LYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GAASIRYSLDEKGKAF--FKIDHMSGWIKT-KNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFE-SYTLEVGVRDKG-KYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELT-IIASDSATKPKMVMLKLIINNH 2401
F +++R ++ L+ E ++Y + +KA DR+ T+ + I V D ND P+F Y V I E+T ++ V A D D G G + Y++ L + F I+ +GEI L ++L + + VVA D + N Q K V I+V+ +N Y P I T V N L + ++V+D D G+N + E+ + LLK E L A + F + + ++ D G+P + +SV + I ++ P F Q IYEVS+ E N V++L +D D G ++ Y G F+I+ SG + T K + +++ T+ +A ++ K+ ++++D NDN PIF V ++ EN ++ + +LTA D D G NS + + + A E+ FS G ++T LD ET + +Y L + D G Y T +++ V D NDN+PQ+ +N +T+ V A D DAG+ I YR+ + ++ F+LD SG + + D + LT I SAT LIIN H
Sbjct: 123 FAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSL-----LMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEI-FTKTFSSVTPTSNPLIYGI--VRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHF----IYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDH-FS----GIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFER---VNCYGKVTKSAPMGTEVFVTSAIDFDAGD--IISYRLSD---GNEDGCFNLDPTSGSLSI--SCDLKKTTLTNRILKVSATDGTHFSDDLIINVH 703 HSP 6 Score: 127.487 bits (319), Expect = 3.815e-29 Identity = 143/532 (26.88%), Postives = 237/532 (44.55%), Query Frame = 2
Query: 683 LRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK-VPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF------GVIPEFTVKENMI-----STRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATST--NVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
+ L LDYET++ Y LT+ D L++ V D NDN P F K+ Y V+I EN + S+++ ++A D+D + Y++ A D + F I+S SG + + +RL + + V KD P K + + V D N+++P +V + L ++ D D G N+++ + T + + + +LA + + Q +K D G+PP S+ V + +T P+F + + EN T V Q+ A ++SI +++ F+I+ +G I N +D E I+ VFN + ++ II+ I D NDN P F G +PE + + S++ L DAD G N VE+ ++ LA+ F + S G IE L+ LD ET YT +V V D GK + ++T +VT++V++ ND P + E N+T + E V Q DA +N +++ I
Sbjct: 1461 ILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDK--KLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQ--GAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVP-ESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAG--NLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTAR---SSSSIFFNIISGNINESFRINPSTGVI-VINGNIDYESIK--VFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAK-----NFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFN-----ERELNVTLFLPTFENVFVRQVSAKDA-DNDTLRFDI 1968 HSP 7 Score: 126.716 bits (317), Expect = 6.966e-29 Identity = 171/703 (24.32%), Postives = 307/703 (43.67%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE-----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK--VPVEITVEDINNYYPVI------------AILSTNERVEVRENTLPGNLITIKVSD-NDIGM--------NSKVNCELQTESKIDFQLLKKK-------------------ENLYSLASV----RSFDF-ESGQVKS-------ASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKII-VTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD--QIELTIIASDSATKPKM 2371
+V +QI + N P+F+ +++ E+ P+N + D D +N + ++ + E + + L +LD E + Y LT+ A D+ + ++ + I VQD NDN PIF +SI EN GS VV + A D+DSG+ + Y+I N + F I+ SG ++ L K + ++ + SD+ P + + + + I V+DIN+ P A + T V + G++I+ ++SD N+ G + ++C+L+ ++ + ++LK E+L +S+ SF+ E+G + A S SP +D S+ N + PEF E+S+ E+ V + A DRD + +++ D + F+ID G ++ LDRE V N +D +P +T+K++ +TI D NDN P+ + F + E+ ++ L ATDAD G N+QV + L E + G + + LDRE ++Y L + +D G +++ V V V D NDN P + I + + + + ++ ++A D D G N I++ + + + +F +D+ +G IR LD++ Q+ I+++ P +
Sbjct: 385 SVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDL-GKNALVYLEIVGGNEGDEFRINPDSGM-LYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAV----PFEIDHFSGIVKTTSLLDFETMK-RNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLK-KTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIG-YLDRERQNEYVLNITVYD-LGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYAL------SVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYI---FKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLK--EETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSL 1066 HSP 8 Score: 110.538 bits (275), Expect = 5.723e-24 Identity = 158/632 (25.00%), Postives = 292/632 (46.20%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDR--DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDT-GSLVVTVNAYDKDSGDLGL-VMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCEL-----QTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD--GAASIRYSLDEKGK-AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRD-KGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN--ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSK--QPVFSLDEDSGEI 2293
++++ + D+NDN PLF + T+ P + A D D SAEN Y+L+ + + F+LD K ++S++ E + Y LT+ A D C+ E + V+ + + P+F K FY VS+ E+ + +L V++ A LG ++Y I + + Q+F I+ N+G I + L + K+ + V + +D + +V + +++ D+N+ YP I S + + EN G ++ I +DND G N+K++ + Q S++ F + NLY + D+E + + D GSP S+ +V + + D+N+ +P F + Y + V A D+D S+ Y + + + ID ++G I +N +L+ + V N D TA ++ +++ EN +P+F E V EN++ I + A+D D G + + + ++ +E++KIF + + G I + + DRE + Y + + V D GK+ A+ L P + EY ++ + N+ ++TV+A D D +NG + ++I K N K + V ++E +G+I
Sbjct: 2125 SIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLD-SAENGEVRYELKKGNGELFKLD-RKSGELSIKQHVE---GHNRNYELTVAAYDGAITPCS-SEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEA----ESPLGRSLIYTISSES-----QSFEIDYNTGSIFVVNEL--DYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIE--SDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSEL-FYIDVTDGNLYLKTPL---DYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQN-MLNFTDKSSTVLNISVSDGV---HTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIV-----SEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFAS--------LKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQ-KSNDKAVKDVIEINEKTGDI 2715 HSP 9 Score: 106.686 bits (265), Expect = 1.016e-22 Identity = 144/614 (23.45%), Postives = 259/614 (42.18%), Query Frame = 2
Query: 725 YRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD-SDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRS-FDFESGQVK-SASIKCTDSGSP-PKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTI----EDENDNAPIFGVIPEFTVKENMISTRL-------------------IGRLTATDADKGNN-SQVEFV-LLKTLARKQEVQ--------------------KIFSVS------------KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIASDSAT 2359
Y LTL A D + K + I ++ E+ N PIFT+ Y+VSI E V+ + D D G LV I N+ D F IN +SG + ++L A ++ YT V A D ++ + ++ V+I+V+D+N+ P+ + N+ + + EN L G+ + + D D G NS ++ + + + F++ ++ + S DFE+ + I+ +D G P + T+ + + + D+N+ P+F+++ + ++ T+V +A D D I Y L D F +D SG + + ++ +T + N + D + +I+ + ED ++ I F +E ++ RL L+ T + G N + EFV + L+ + VQ +F++S G ++ + LDRE Y L + V D G +TS + + +LD NDN+P + +T +V + A D D+G N ++ Y + + + F+++ +G +RL K LD D L I A D +
Sbjct: 366 YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGD---EFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFE--NVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEI----DHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLS-----ISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQK---TLATFRLTESARIGTVVHCLHATDADSGINAQVTYAL-----SVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGS 957 HSP 10 Score: 105.916 bits (263), Expect = 1.717e-22 Identity = 153/646 (23.68%), Postives = 277/646 (42.88%), Query Frame = 2
Query: 470 LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI-DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDND-IGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNA--TDRDGAASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKG---KYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDS 2353
+ I D+NDN P+ T L ES + + A D D S N +Y L + F ++ + LRL LD E + Y L + A D S ++ + + V D NDN P+F Y + E+ G+++ + A D+D G + +++ + D +L F I+ ++G IR + L ++++ V A D +P + + I + D+N +V+EN G + + D D + +NSK+ + + + + ++ SL+ + D E+ ++ D P S V + + + N+ P + +Y V++ E + N +++ L A D D +I Y++ +F+ID +G IKT LDRE + D ++T++I+V++ D NDN+P F + + V + + I ++ A D+D G N ++ + + + + F + S+ G I + LD + + + + D G K A V V V + N P + N ++T LV + A D D N ++ Y I N ++ F + +D+G I L K LD++ + LTI +D
Sbjct: 865 ITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDAD-SGINAQVTYALSVECSDFTVNATTG---CLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEEL---FRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDG--GDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQL---DAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNK-----FRIDSQRGHIHIAKPLDSDN--EFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENV-VDLTENDKPGFLVTQILAVDDD---NDQLWYNISNGNDDN---TFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG 1484 HSP 11 Score: 103.605 bits (257), Expect = 8.707e-22 Identity = 140/564 (24.82%), Postives = 246/564 (43.62%), Query Frame = 2
Query: 701 LDYETRKQYRLTLKACD----------RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLL----------KKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL------DEKGKAFFKIDHMSG--WIKTKNVVLDREVIE--TIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTR--LIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYT-LEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEI 2293
D E + YRL ++A R + T + I V D NDN P+F Y ++ + G++++ V A D DS + G V Y + N + F ++ SGE+ +++ + + R Y V A D P + P+++ V I+ PV T+ V + D+ M S ++ ++ ES + L+ + N S+ V D+E SI+ TDS S + + + V I D+N+ PE + IY +++ EN + T++L++NATD D A+ + S + F ID G ++KT LD E I+ IV N H + ++ + + +T++D NDNAP F V P + K ++ + R + A D D + +E+ + E+Q +S+ K + +LQ++ T +S T L + V D A + + +L EN P + + E + + ++TV+A D D G + Y I + + + +F +D+ +G I
Sbjct: 2093 FDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSID--ISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNG----ELFKLDRKSGELSIKQHVEGHNRN-YELTVAAYDGAI-TPCSSEAPLQVKV--IDRSMPV----------------FEKQFYTVSVKE-DVEMYSALSVSIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYA-EVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTP---LDYEQIKYHHIVVNVKDHGS--PSLSSRSNVFITVKDLNDNAPCF-VEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEY----KIVYGNELQT-YSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYA---RLKISLLPENVYSPLF---DQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEE---MKKIFLIDQTTGVI 2608 HSP 12 Score: 99.7525 bits (247), Expect = 1.207e-20 Identity = 138/556 (24.82%), Postives = 253/556 (45.50%), Query Frame = 2
Query: 470 LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDV--QDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVL-VHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEF--TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW 2104
LQ+ ++ + P+F T++++E + + ++S+ + S R Y + S FE+D + S+ + +ELDYE + ++++A D S E+++ V D ND P + Y ++I EN G+ ++ +NA D DSG + Y I++ N + + F I+ G + L+ L Q K + H+V D +P + V ITV+D+N+ P S +V V + G + + K D DI + ++ +++ + K + SL ++ +F +S V + S+ S T + L + + N YSP F Q YE + EN ++ + A+D D A++ Y + E+ K F ID +G I +K V DRE + V D A+ K V + D NDN P F ++ E+ V + + + I + A D D +N V F +++ + + V+ + ++ K G I + SY V D+G+ + V++++++ + N P +
Sbjct: 2229 LQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAE---SPLGRSLIYTISSESQSFEID---YNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYH--HIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVA--AVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISV------SDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSK-VTFDREKKDEYVVLLKVSDGGGKFGFASLK--VIVVDVNDNVPYF-LLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQK-SNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTF 2763
BLAST of Protocadherin vs. Ensembl Fly
Match: kug (gene:FBgn0261574 transcript:FBtr0346077) HSP 1 Score: 196.438 bits (498), Expect = 2.165e-50 Identity = 175/644 (27.17%), Postives = 300/644 (46.58%), Query Frame = 2
Query: 488 NDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSS--NKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERV-EVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNE--YSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA---ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEF-VLLKTLARKQEVQKIFSVSKEGFIETLQ-SLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD-QIELTIIASDSATKPK 2368
N + P F Q +++ ES+ + +++ A DRD ++ + + D + F +D + L++ LD E + +Y L + D + T K L I + D NDN+P+ K + E+ G++V ++A D DSG V Y + F +N+ +G +RL + L ++ Y H+ AKD E + V + V+D+N+ PV + E + +VRE+ G L I+ D DIG N+++ L+ E++ D +L + ++ ++ + D+E+ QV + + D G P ++D S+++ I D+NE ++PEF +YE ++EN T V+ + A D D + I YS+ G F ++ LD E A D + P + ++ + +E+ENDN P+ + V E + I L A D D + + ++ L E+ SK G I+T + LDRE + LEV + D G +++++ + V VLD NDN P++ + + + N+ + V A D+D+GENGRI Y I + K +K F +D G I + K LD D + E+ I A D+ K
Sbjct: 766 NVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKL-VFAISDGDYDSVFRIDPDRG---ELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVE-----CSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEAL-VYVLVDDVNDNAPVFGV---QEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQ-DEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQ--LDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEID-----SKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEF---DQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNK---FRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKK 1382 HSP 2 Score: 177.948 bits (450), Expect = 1.272e-44 Identity = 212/752 (28.19%), Postives = 333/752 (44.28%), Query Frame = 2
Query: 197 LTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQ--------FLQIND-NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLP---VNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTD------KELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQ-TFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE-KVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW-MNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKP 2365
+ V + NQ I +K D + S+ F + + ++IN+ GD+ K + E+ NS QF V +DR + F + V+++I + + N P F + + ES P V + + + FS + + + DS L L+ LD E ++ + L + A ++ T +++IDV+DENDN P F FY S+ EN++ +V V+A D D+G G + Y +++ D + IQ F I+ SG I L L + Y F V+A D+ +P+ + KVPV I + D N+ PV + E + V EN LPG LI + + D DI + + + FQ+ K E L + D E + SI TD K+ +V + + D+N+ +P + Y +S E+ + T ++++ A D D + +R+ L KG F I SG +K + LDRE A D ++II+T+ D NDN PIF + +V E+ LI ++ A D D G N Q+++ L+ E F +SK G I +SLDRET + L V D G + + V V +LD NDN P++ M N T V V A D G N I Y I + ++Q F +D +G++ L LD++ + LTI A D T P
Sbjct: 2661 MVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSK--AESYGVNSY----QFF------VRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIAADQDHFMISDSG-------------ELILQQTLDREQQESHNLIVVA---ETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLES--DTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADN--GHPKHDAKVPVTIKIVDYNDNAPVFKL--PIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGE----LFIAKPLDREQLMFYNLSIIATDGKFTAKA---NVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVAS-ALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMG------ENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATH----GTEVCKVYATSIDIGVNADIHYFIMS---GNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPP 3357 HSP 3 Score: 155.992 bits (393), Expect = 8.014e-38 Identity = 183/736 (24.86%), Postives = 322/736 (43.75%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPD----KLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDK---ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQT-ESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKAF--FKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKG-NNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDS 2353
L+V E P + N+ PD ++ F + + +QF QI +G++ + K +D E L F ++ D F V + + D+NDNTP I+ ES+ + ++ A D DF ++ R Y ++ F + K I L++ S LD ET +Y+L D T + E+II V D NDN PIF+ Y+VS+ E+ +L+ V+A DKD G + Y++ N F I+ ++G IRL + L ++ + F++ K D P+ + V + + DIN+ P ++ + ++ EN G + + + DIG+N+ ++ + + + F++ +L A++ D+E + +I+ D G+PP S + V + I D+N+ SP F Q +Y +++ E+ +K+L + ATD D + + Y++ E+G F ID +G I LDRE I A D + I + I D NDNAPIF ++EN + + +DAD+ N + F + R +F + ++G + T + + + ++V V D G P+ + V VK+++E+ P P+ N + V A D D + +F++ ++G+I + LD +L + SD
Sbjct: 2973 GLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQF-QIGKSGELFIAKPLDREQLM------------FYNLSIIATD-GKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRF--YLSGKGADDFSI--GKESGI-LKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENH----DYFKISKSTGIIRLHKSL--DRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYS--CKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATL---DYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNI-ERGDNIGQFSIDPKNGTISVSR-PLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDI-----RSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIV---TPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDG 3668 HSP 4 Score: 153.68 bits (387), Expect = 3.656e-37 Identity = 177/669 (26.46%), Postives = 294/669 (43.95%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNK--PIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDL-GLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYP-----VIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDE-KGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTK---IIVTIEDENDNAP-IFGVIPEFTV--KENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKPKMVMLKLIINNH 2401
V + ++D+NDN P+F E +RE LP +++ A D D I+ + L++ + EL ++R + LDYE ++ + L + A D +D ++I + D N+N+ P F Y+ + EN G+ V+ V A D D+ DL + Y+I + L + F +N + G I +L A + Y + A+D P V V I VE+ N+ P V + T VE E +IT+K D DI + + + + + + + K + R D E+ + +D+GSP S+ ++V + D+N+ SPEF Q +Y+V + + N + Q++A D D I YS+ KGK F+ID G I + E + A D + + T + ++V + + NAP I E V EN L+ ++ A D D N Q L ++ + + G I + LD ET +SY L + V D TN+ V+V+D NDN PQ+ NI+ I + ++M + A D D E+ ++ Y +H + S +F +D SG + + + LDF++ L + D K K+I+N H
Sbjct: 966 VYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQ-FSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGI---FAVN-DQGSITSLSQLDAETKNFYWLTLCAQDCAIV-PLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVE------IITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTE-RKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFE---IHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQ----LWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG---TFTAFTNLLVQVIDINDNPPQFAKD---VYHVNISENIEEESVIMQLHATDRD--EDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVH 1603 HSP 5 Score: 129.413 bits (324), Expect = 1.115e-29 Identity = 169/608 (27.80%), Postives = 273/608 (44.90%), Query Frame = 2
Query: 668 FPQISLRLKSE---LDYETRKQYRLTLKAC----DRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDS----DFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVN-CELQTESKIDFQLLKKKEN-------LYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GAASIRYSLDEKGKAF--FKIDHMSGWIKT-KNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFE-SYTLEVGVRDKG-KYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELT-IIASDSATKPKMVMLKLIINNH 2401
F +++R ++ L+ E ++Y + +KA DR+ T+ + I V D ND P+F Y V I E+T ++ V A D D G G + Y++ L + F I+ +GEI L ++L + + VVA D + N Q K V I+V+ +N Y P I T V N L + ++V+D D G+N + E+ + LLK E L A + F + + ++ D G+P + +SV + I ++ P F Q IYEVS+ E N V++L +D D G ++ Y G F+I+ SG + T K + +++ T+ +A ++ K+ ++++D NDN PIF V ++ EN ++ + +LTA D D G NS + + + A E+ FS G ++T LD ET + +Y L + D G Y T +++ V D NDN+PQ+ +N +T+ V A D DAG+ I YR+ + ++ F+LD SG + + D + LT I SAT LIIN H
Sbjct: 123 FAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSL-----LMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEI-FTKTFSSVTPTSNPLIYGI--VRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHF----IYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDH-FS----GIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQF---ERVNCYGKVTKSAPMGTEVFVTSAIDFDAGD--IISYRLSD---GNEDGCFNLDPTSGSLSI--SCDLKKTTLTNRILKVSATDGTHFSDDLIINVH 703 HSP 6 Score: 127.102 bits (318), Expect = 4.635e-29 Identity = 143/532 (26.88%), Postives = 237/532 (44.55%), Query Frame = 2
Query: 683 LRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK-VPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF------GVIPEFTVKENMI-----STRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATST--NVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
+ L LDYET++ Y LT+ D L++ V D NDN P F K+ Y V+I EN + S+++ ++A D+D + Y++ A D + F I+S SG + + +RL + + V KD P K + + V D N+++P +V + L ++ D D G N+++ + T + + + +LA + + Q +K D G+PP S+ V + +T P+F + + EN T V Q+ A ++SI +++ F+I+ +G I N +D E I+ VFN + ++ II+ I D NDN P F G +PE + + S++ L DAD G N VE+ ++ LA+ F + S G IE L+ LD ET YT +V V D GK + ++T +VT++V++ ND P + E N+T + E V Q DA +N +++ I
Sbjct: 1461 ILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDK--KLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQ--GAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVP-ESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAG--NLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTAR---SSSSIFFNIISGNINESFRINPSTGVI-VINGNIDYESIK--VFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAK-----NFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFN-----ERELNVTLFLPTFENVFVRQVSAKDA-DNDTLRFDI 1968 HSP 7 Score: 126.331 bits (316), Expect = 8.755e-29 Identity = 171/703 (24.32%), Postives = 307/703 (43.67%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE-----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK--VPVEITVEDINNYYPVI------------AILSTNERVEVRENTLPGNLITIKVSD-NDIGM--------NSKVNCELQTESKIDFQLLKKK-------------------ENLYSLASV----RSFDF-ESGQVKS-------ASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKII-VTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD--QIELTIIASDSATKPKM 2371
+V +QI + N P+F+ +++ E+ P+N + D D +N + ++ + E + + L +LD E + Y LT+ A D+ + ++ + I VQD NDN PIF +SI EN GS VV + A D+DSG+ + Y+I N + F I+ SG ++ L K + ++ + SD+ P + + + + I V+DIN+ P A + T V + G++I+ ++SD N+ G + ++C+L+ ++ + ++LK E+L +S+ SF+ E+G + A S SP +D S+ N + PEF E+S+ E+ V + A DRD + +++ D + F+ID G ++ LDRE V N +D +P +T+K++ +TI D NDN P+ + F + E+ ++ L ATDAD G N+QV + L E + G + + LDRE ++Y L + +D G +++ V V V D NDN P + I + + + + ++ ++A D D G N I++ + + + +F +D+ +G IR LD++ Q+ I+++ P +
Sbjct: 385 SVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDL-GKNALVYLEIVGGNEGDEFRINPDSGM-LYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAV----PFEIDHFSGIVKTTSLLDFETMK-RNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLK-KTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIG-YLDRERQNEYVLNITVYD-LGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYAL------SVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYI---FKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLK--EETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSL 1066 HSP 8 Score: 110.538 bits (275), Expect = 6.387e-24 Identity = 158/632 (25.00%), Postives = 292/632 (46.20%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDR--DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDT-GSLVVTVNAYDKDSGDLGL-VMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCEL-----QTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD--GAASIRYSLDEKGK-AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRD-KGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN--ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSK--QPVFSLDEDSGEI 2293
++++ + D+NDN PLF + T+ P + A D D SAEN Y+L+ + + F+LD K ++S++ E + Y LT+ A D C+ E + V+ + + P+F K FY VS+ E+ + +L V++ A LG ++Y I + + Q+F I+ N+G I + L + K+ + V + +D + +V + +++ D+N+ YP I S + + EN G ++ I +DND G N+K++ + Q S++ F + NLY + D+E + + D GSP S+ +V + + D+N+ +P F + Y + V A D+D S+ Y + + + ID ++G I +N +L+ + V N D TA ++ +++ EN +P+F E V EN++ I + A+D D G + + + ++ +E++KIF + + G I + + DRE + Y + + V D GK+ A+ L P + EY ++ + N+ ++TV+A D D +NG + ++I K N K + V ++E +G+I
Sbjct: 2125 SIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLD-SAENGEVRYELKKGNGELFKLD-RKSGELSIKQHVE---GHNRNYELTVAAYDGAITPCS-SEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEA----ESPLGRSLIYTISSES-----QSFEIDYNTGSIFVVNEL--DYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIE--SDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSEL-FYIDVTDGNLYLKTPL---DYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQN-MLNFTDKSSTVLNISVSDGV---HTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIV-----SEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFAS--------LKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQ-KSNDKAVKDVIEINEKTGDI 2715 HSP 9 Score: 106.301 bits (264), Expect = 1.203e-22 Identity = 144/614 (23.45%), Postives = 259/614 (42.18%), Query Frame = 2
Query: 725 YRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD-SDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRS-FDFESGQVK-SASIKCTDSGSP-PKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTI----EDENDNAPIFGVIPEFTVKENMISTRL-------------------IGRLTATDADKGNN-SQVEFV-LLKTLARKQEVQ--------------------KIFSVS------------KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIASDSAT 2359
Y LTL A D + K + I ++ E+ N PIFT+ Y+VSI E V+ + D D G LV I N+ D F IN +SG + ++L A ++ YT V A D ++ + ++ V+I+V+D+N+ P+ + N+ + + EN L G+ + + D D G NS ++ + + + F++ ++ + S DFE+ + I+ +D G P + T+ + + + D+N+ P+F+++ + ++ T+V +A D D I Y L D F +D SG + + ++ +T + N + D + +I+ + ED ++ I F +E ++ RL L+ T + G N + EFV + L+ + VQ +F++S G ++ + LDRE Y L + V D G +TS + + +LD NDN+P + +T +V + A D D+G N ++ Y + + + F+++ +G +RL K LD D L I A D +
Sbjct: 366 YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGD---EFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFE--NVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEI----DHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLS-----ISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLAT---FRLTESARIGTVVHCLHATDADSGINAQVTYAL-----SVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGS 957 HSP 10 Score: 105.531 bits (262), Expect = 2.015e-22 Identity = 153/646 (23.68%), Postives = 277/646 (42.88%), Query Frame = 2
Query: 470 LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI-DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDND-IGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNA--TDRDGAASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKG---KYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDS 2353
+ I D+NDN P+ T L ES + + A D D S N +Y L + F ++ + LRL LD E + Y L + A D S ++ + + V D NDN P+F Y + E+ G+++ + A D+D G + +++ + D +L F I+ ++G IR + L ++++ V A D +P + + I + D+N +V+EN G + + D D + +NSK+ + + + + ++ SL+ + D E+ ++ D P S V + + + N+ P + +Y V++ E + N +++ L A D D +I Y++ +F+ID +G IKT LDRE + D ++T++I+V++ D NDN+P F + + V + + I ++ A D+D G N ++ + + + + F + S+ G I + LD + + + + D G K A V V V + N P + N ++T LV + A D D N ++ Y I N ++ F + +D+G I L K LD++ + LTI +D
Sbjct: 865 ITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDAD-SGINAQVTYALSVECSDFTVNATTG---CLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEEL---FRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDG--GDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQL---DAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNK-----FRIDSQRGHIHIAKPLDSDN--EFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENV-VDLTENDKPGFLVTQILAVDDD---NDQLWYNISNGNDDN---TFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG 1484 HSP 11 Score: 103.219 bits (256), Expect = 1.048e-21 Identity = 140/564 (24.82%), Postives = 246/564 (43.62%), Query Frame = 2
Query: 701 LDYETRKQYRLTLKACD----------RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLL----------KKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL------DEKGKAFFKIDHMSG--WIKTKNVVLDREVIE--TIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTR--LIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYT-LEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEI 2293
D E + YRL ++A R + T + I V D NDN P+F Y ++ + G++++ V A D DS + G V Y + N + F ++ SGE+ +++ + + R Y V A D P + P+++ V I+ PV T+ V + D+ M S ++ ++ ES + L+ + N S+ V D+E SI+ TDS S + + + V I D+N+ PE + IY +++ EN + T++L++NATD D A+ + S + F ID G ++KT LD E I+ IV N H + ++ + + +T++D NDNAP F V P + K ++ + R + A D D + +E+ + E+Q +S+ K + +LQ++ T +S T L + V D A + + +L EN P + + E + + ++TV+A D D G + Y I + + + +F +D+ +G I
Sbjct: 2093 FDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSID--ISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNG----ELFKLDRKSGELSIKQHVEGHNRN-YELTVAAYDGAI-TPCSSEAPLQVKV--IDRSMPV----------------FEKQFYTVSVKE-DVEMYSALSVSIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYA-EVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTP---LDYEQIKYHHIVVNVKDHGS--PSLSSRSNVFITVKDLNDNAPCF-VEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEY----KIVYGNELQT-YSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYA---RLKISLLPENVYSPLF---DQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEE---MKKIFLIDQTTGVI 2608 HSP 12 Score: 99.3673 bits (246), Expect = 1.417e-20 Identity = 138/556 (24.82%), Postives = 253/556 (45.50%), Query Frame = 2
Query: 470 LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQ--DENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVL-VHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEF--TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW 2104
LQ+ ++ + P+F T++++E + + ++S+ + S R Y + S FE+D + S+ + +ELDYE + ++++A D S E+++ V D ND P + Y ++I EN G+ ++ +NA D DSG + Y I++ N + + F I+ G + L+ L Q K + H+V D +P + V ITV+D+N+ P S +V V + G + + K D DI + ++ +++ + K + SL ++ +F +S V + S+ S T + L + + N YSP F Q YE + EN ++ + A+D D A++ Y + E+ K F ID +G I +K V DRE + V D A+ K V + D NDN P F ++ E+ V + + + I + A D D +N V F +++ + + V+ + ++ K G I + SY V D+G+ + V++++++ + N P +
Sbjct: 2229 LQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAE---SPLGRSLIYTISSESQSFEID---YNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYH--HIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVA--AVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISV------SDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSK-VTFDREKKDEYVVLLKVSDGGGKFGFASLK--VIVVDVNDNVPYF-LLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQK-SNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTF 2763
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: si:ch73-233f7.1 (si:ch73-233f7.1 [Source:ZFIN;Acc:ZDB-GENE-141215-5]) HSP 1 Score: 246.514 bits (628), Expect = 2.165e-67 Identity = 199/661 (30.11%), Postives = 330/661 (49.92%), Query Frame = 2
Query: 200 TVKEEFKPNQFIGNIKYALP-DKLKFSSLKFNVDS----QFLQIN-DNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVE--DINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDG--AASIRYSLDE---KG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-------GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLD 2080
++ EE + F+GNI L D K SS +F + S Q+L++N +NG + + ++ID E LC+ S +C F+ +V++ + ++ V ++I D+NDN P F E + + ES LESA D D + N + SY L ++ F LD SKF + L L+S+LD E +K + + L A D S ++ + V D NDN P+F ++ Y+VS++EN G+LV+ +NA D D G G + Y+ L + + F ++S+SGEIR++ + + +Y +V AKD P V ++ V+ D+N+ P + + S + V+E+ PG +I I V D D G N V+C Q + FQL +N Y+L + D ES + ++ D GSPP ST +++LV ++D+N+ P F Q Y V + EN A + + A D D A + YS+ E +G + I+ +G I D E + A DA P ++ + V + D+NDNAP+ G + V ++ S L+ ++TA DAD G NS++ + +L+ +FSV+ G I T++ + L + V+D G+ P++ + ++ + V+D
Sbjct: 36 SIPEELEHGAFVGNIAEDLGLDVAKLSSRRFRIVSGARKQYLEVNLENGILFVNEKIDREELCEQSPVC------FLHLQVVIENP---LELYRVEVEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLESAQDLDVGS-NSLRSYLLS-ANQHFVLDIQTRNDGSKFAE--LVLQSQLDREQQKMHEMVLTAVDGGSPLRSGTAQITVTVLDANDNVPVFDRSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSFSGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKD---KGPSAVAVHCKVLVDILDVNDNAPEVILTSVS--TPVQEDAPPGTVIAVISVMDRDSGENGAVDC--QIPGNVPFQLHSSFKNYYTLVTSEFLDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRFIQPSYTVYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQIQGMPVSTYVSINSDNGNIYALR-SFDYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGYLVAKITALDADAGQNSRLSYQVLQATD-----PGLFSVALYTGEIRTIRRFVDKDAIRQRLVILVKDNGQPPLSATVSIILSVVD 670 HSP 2 Score: 157.147 bits (396), Expect = 1.684e-38 Identity = 147/554 (26.53%), Postives = 246/554 (44.40%), Query Frame = 2
Query: 782 IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDL-IQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSF-DFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMS---GWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTV--KENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN---ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKE-LDFDQI--ELTIIASDSATKPKMVMLKLIIN 2395
+++ D NDN P F + + + I E+ GS +A D D G L Y + A L IQT S E+ L+ +L Q+K++ + A D +P + + +TV D N+ PV + RV + EN G L+ + +D D G N ++ + + + L ++ V+ D+E V ++ D G + VLV I D+N+ +PE ++E+ T + ++ DRD + G F++ H S + + LDRE + A D P + I+V + D NDN P F + P +TV EN I +TA D D N+ + + +L+ + V S+ S G I L+S D E ++ + V +D G P++++ V V VLD+NDN P ++P P N + R ++ LV + A D DAG+N R+ Y++ + +FS+ +GEIR ++ +D D I L I+ D+ P + +I++
Sbjct: 123 VEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLESAQDLDVGSNSLRSYLLSANQHFVLDIQTRNDGSKFAELVLQSQLDREQQKMHEMVLTAVDG--GSPLRSGTAQITVTVLDANDNVPVFD--RSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSFSGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKDKGPSAVAVHCKVLVDILDVNDNAPEVILTSVSTPVQEDAPPGTVIAVISVMDRDSGENGAVDCQIPGNVPFQL-HSSFKNYYTLVTSEFLDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRF-IQPSYTVYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQIQGMPVSTYVSINSDNGNIYALRSFDYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGYLVAKITALDADAGQNSRLSYQVLQ---ATDPGLFSVALYTGEIRTIRRFVDKDAIRQRLVILVKDNGQPPLSATVSIILS 667
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: si:ch73-233f7.1 (si:ch73-233f7.1 [Source:ZFIN;Acc:ZDB-GENE-141215-5]) HSP 1 Score: 246.514 bits (628), Expect = 2.776e-67 Identity = 198/661 (29.95%), Postives = 328/661 (49.62%), Query Frame = 2
Query: 200 TVKEEFKPNQFIGNIKYALP-DKLKFSSLKFNVDS----QFLQIN-DNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVE--DINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDG--AASIRYSLDEKG------KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-------GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLD 2080
++ EE + F+GNI L D K SS +F + S Q+L++N +NG + + ++ID E LC+ S +C F+ +V++ + ++ V ++I D+NDN P F E + + ES LESA D D + N + SY L ++ F LD SKF + L L+S+LD E +K + + L A D S ++ + V D NDN P+F ++ Y+VS++EN G+LV+ +NA D D G G + Y+ L + + F ++S+SGEIR++ + + +Y +V AKD P V ++ V+ D+N+ P + + S + V+E+ PG +I I V D D G N V+C Q + FQL +N Y+L + D ES + ++ D GSPP ST +++LV ++D+N+ P F Q Y V + EN A + + A D D A + YS+ E + I+ +G I D E + A DA P ++ + V + D+NDNAP+ G + V ++ S L+ ++TA DAD G NS++ + +L+ +FSV+ G I T++ + L + V+D G+ P++ + ++ + V+D
Sbjct: 36 SIPEELEHGAFVGNIAEDLGLDVAKLSSRRFRIVSGARKQYLEVNLENGILFVNEKIDREELCEQSPVC------FLHLQVVIENP---LELYRVEVEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLESAQDLDVGS-NSLRSYLLS-ANQHFVLDIQTRNDGSKFAE--LVLQSQLDREQQKMHEMVLTAVDGGSPLRSGTAQITVTVLDANDNVPVFDRSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSFSGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKD---KGPSAVAVHCKVLVDILDVNDNAPEVILTSVS--TPVQEDAPPGTVIAVISVMDRDSGENGAVDC--QIPGNVPFQLHSSFKNYYTLVTSEFLDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRFIQPSYTVYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQIQGMPVSTYVSINSDNGNIYALR-SFDYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGYLVAKITALDADAGQNSRLSYQVLQATD-----PGLFSVALYTGEIRTIRRFVDKDAIRQRLVILVKDNGQPPLSATVSIILSVVD 670 HSP 2 Score: 157.147 bits (396), Expect = 1.592e-38 Identity = 147/554 (26.53%), Postives = 246/554 (44.40%), Query Frame = 2
Query: 782 IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDL-IQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSF-DFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMS---GWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTV--KENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN---ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKE-LDFDQI--ELTIIASDSATKPKMVMLKLIIN 2395
+++ D NDN P F + + + I E+ GS +A D D G L Y + A L IQT S E+ L+ +L Q+K++ + A D +P + + +TV D N+ PV + RV + EN G L+ + +D D G N ++ + + + L ++ V+ D+E V ++ D G + VLV I D+N+ +PE ++E+ T + ++ DRD + G F++ H S + + LDRE + A D P + I+V + D NDN P F + P +TV EN I +TA D D N+ + + +L+ + V S+ S G I L+S D E ++ + V +D G P++++ V V VLD+NDN P ++P P N + R ++ LV + A D DAG+N R+ Y++ + +FS+ +GEIR ++ +D D I L I+ D+ P + +I++
Sbjct: 123 VEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLESAQDLDVGSNSLRSYLLSANQHFVLDIQTRNDGSKFAELVLQSQLDREQQKMHEMVLTAVDG--GSPLRSGTAQITVTVLDANDNVPVFD--RSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSFSGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKDKGPSAVAVHCKVLVDILDVNDNAPEVILTSVSTPVQEDAPPGTVIAVISVMDRDSGENGAVDCQIPGNVPFQL-HSSFKNYYTLVTSEFLDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRF-IQPSYTVYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQIQGMPVSTYVSINSDNGNIYALRSFDYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGYLVAKITALDADAGQNSRLSYQVLQ---ATDPGLFSVALYTGEIRTIRRFVDKDAIRQRLVILVKDNGQPPLSATVSIILS 667
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: si:ch73-233f7.1 (si:ch73-233f7.1 [Source:ZFIN;Acc:ZDB-GENE-141215-5]) HSP 1 Score: 243.432 bits (620), Expect = 5.074e-67 Identity = 199/661 (30.11%), Postives = 330/661 (49.92%), Query Frame = 2
Query: 200 TVKEEFKPNQFIGNIKYALP-DKLKFSSLKFNVDS----QFLQIN-DNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVE--DINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDG--AASIRYSLDE---KG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-------GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLD 2080
++ EE + F+GNI L D K SS +F + S Q+L++N +NG + + ++ID E LC+ S +C F+ +V++ + ++ V ++I D+NDN P F E + + ES LESA D D + N + SY L ++ F LD SKF + L L+S+LD E +K + + L A D S ++ + V D NDN P+F ++ Y+VS++EN G+LV+ +NA D D G G + Y+ L + + F ++S+SGEIR++ + + +Y +V AKD P V ++ V+ D+N+ P + + S + V+E+ PG +I I V D D G N V+C Q + FQL +N Y+L + D ES + ++ D GSPP ST +++LV ++D+N+ P F Q Y V + EN A + + A D D A + YS+ E +G + I+ +G I D E + A DA P ++ + V + D+NDNAP+ G + V ++ S L+ ++TA DAD G NS++ + +L+ +FSV+ G I T++ + L + V+D G+ P++ + ++ + V+D
Sbjct: 36 SIPEELEHGAFVGNIAEDLGLDVAKLSSRRFRIVSGARKQYLEVNLENGILFVNEKIDREELCEQSPVC------FLHLQVVIENP---LELYRVEVEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLESAQDLDVGS-NSLRSYLLS-ANQHFVLDIQTRNDGSKFAE--LVLQSQLDREQQKMHEMVLTAVDGGSPLRSGTAQITVTVLDANDNVPVFDRSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSFSGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKD---KGPSAVAVHCKVLVDILDVNDNAPEVILTSVS--TPVQEDAPPGTVIAVISVMDRDSGENGAVDC--QIPGNVPFQLHSSFKNYYTLVTSEFLDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRFIQPSYTVYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQIQGMPVSTYVSINSDNGNIYALR-SFDYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGYLVAKITALDADAGQNSRLSYQVLQATD-----PGLFSVALYTGEIRTIRRFVDKDAIRQRLVILVKDNGQPPLSATVSIILSVVD 670 HSP 2 Score: 155.221 bits (391), Expect = 4.897e-38 Identity = 147/554 (26.53%), Postives = 246/554 (44.40%), Query Frame = 2
Query: 782 IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDL-IQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSF-DFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMS---GWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTV--KENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN---ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKE-LDFDQI--ELTIIASDSATKPKMVMLKLIIN 2395
+++ D NDN P F + + + I E+ GS +A D D G L Y + A L IQT S E+ L+ +L Q+K++ + A D +P + + +TV D N+ PV + RV + EN G L+ + +D D G N ++ + + + L ++ V+ D+E V ++ D G + VLV I D+N+ +PE ++E+ T + ++ DRD + G F++ H S + + LDRE + A D P + I+V + D NDN P F + P +TV EN I +TA D D N+ + + +L+ + V S+ S G I L+S D E ++ + V +D G P++++ V V VLD+NDN P ++P P N + R ++ LV + A D DAG+N R+ Y++ + +FS+ +GEIR ++ +D D I L I+ D+ P + +I++
Sbjct: 123 VEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLESAQDLDVGSNSLRSYLLSANQHFVLDIQTRNDGSKFAELVLQSQLDREQQKMHEMVLTAVDG--GSPLRSGTAQITVTVLDANDNVPVFD--RSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSFSGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKDKGPSAVAVHCKVLVDILDVNDNAPEVILTSVSTPVQEDAPPGTVIAVISVMDRDSGENGAVDCQIPGNVPFQL-HSSFKNYYTLVTSEFLDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRF-IQPSYTVYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQIQGMPVSTYVSINSDNGNIYALRSFDYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGYLVAKITALDADAGQNSRLSYQVLQA---TDPGLFSVALYTGEIRTIRRFVDKDAIRQRLVILVKDNGQPPLSATVSIILS 667
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 243.432 bits (620), Expect = 3.591e-66 Identity = 240/806 (29.78%), Postives = 373/806 (46.28%), Query Frame = 2
Query: 98 YSLIKPKF--SMMNIFLILWIFANFEFRVNCWTANLT------VKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVND--RNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL---EDSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE--KVPVEITVEDINNYYPVIAI----LSTNER--VEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKEN------LYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG--KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNEL-VMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPK 2368
+S ++P ++ N +++WI C +AN+ V EE PN IG++ LPD K V + +L+++ GD+ T + ID E+L N+ G CF++ +V + D + + ++I D NDNTP FS+ T+++ E+ V ++ A DRD S N I Y L +++N F L + K PQ L + LD E R Y L +K D S + L I + D NDN P F ++ Y+ + EN+ G V+ V A D D G G V Y++ P+ +++ I+ N+G I ++ + + + F+V AKD N PQ + K V ITV+D N+ P I I L T+E + E+ G + ++VSD D G N+ V C + + + FQL E Y L + D+E + I DSG+P S+ S+ V +TDMN+ +P F +YEV E KVL + ATD D A + YS+ + F+I+ +G ++ + LDRE ++ F A D V T ++V + D NDN P F + F+V+ENM +G +T D D+G N++V+ L+ + + K + I + S DRE +Y+ + D G P ++ +T+ VLDENDN P P N Y E V +V+A D D G N + + I P+ +F + + GEI L KE I L + D T P+
Sbjct: 20 FSPLQPLLHSALFNYAMLVWILLLL-----CCSANVVNTILYQVTEEQPPNTLIGSLASDQGLPDTGHL--YKLEVGAPYLRVDGKTGDIYTTENSIDRESLKDCRNLFEGD-PCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRD-SGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQ--LIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSS-PVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKD---NGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGD--VPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMS-QLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQ------LSVEPDNGKFMIQNGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVT--KPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHG---LFRISSE-GEITLAKEFTPKHIGLHRLVVKVKDKGTPPR 795 HSP 2 Score: 75.485 bits (184), Expect = 3.226e-13 Identity = 89/344 (25.87%), Postives = 155/344 (45.06%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFS-TIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSS---NKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDK---ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQ--TFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKK-ENLYSLAS------VRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHI 1441
++ +Q+ D+NDN P+FS T+ + E+ P + + + A D D S N +Y + S FE++ + +R+ S+LD E Y+ + A D+ + + +++ V D NDN P F N Y S+ EN S V V D D G+ V +++ N +IQ T+ I S I +R + Y+F + A D + P+ V + I V D N+ P + + + + T P + +++ D DIG+NS+ +DF ++ L+ ++S + F + + +K D G+PP+ T + LVHI
Sbjct: 485 SLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDV-VATDAD-SGTNAELTYSITGGSVPEGLFEINPNTG---EVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILST---ISFDRE----KESTYSFRLKAVDGG-DPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSE----------LDFNIVGGNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQT--TALVHI 803
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 243.817 bits (621), Expect = 4.359e-66 Identity = 238/792 (30.05%), Postives = 370/792 (46.72%), Query Frame = 2
Query: 116 KFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVND--RNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE---DSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE--KVPVEITVEDINNYYPVIAI----LSTNER--VEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENL------YSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG--KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNEL-VMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPK 2368
++S M ++++L + C +AN+ V EE PN IG++ LPD K V + +L+++ GD+ T + ID E+L N+ G CF++ +V + D + + ++I D NDNTP FS+ T+++ E+ V ++ A DRD S N I Y L +++N F L + K PQ L + LD E R Y L +K D S + L I + D NDN P F ++ Y+ + EN+ G V+ V A D D G G V Y++ P+ +++ I+ N+G I ++ + + + F+V AKD N PQ + K V ITV+D N+ P I I L T+E + E+ G + ++VSD D G N+ V C + + + FQL E Y L + D+E + I DSG+P S+ S+ V +TDMN+ +P F +YEV E KVL + ATD D A + YS+ + F+I+ +G ++ + LDRE ++ F A D V T ++V + D NDN P F + F+V+ENM +G +T D D+G N++V+ L+ + + K + I + S DRE +Y+ + D G P ++ +T+ VLDENDN P P N Y E V +V+A D D G N + + I P+ +F + + GEI L KE I L + D T P+
Sbjct: 41 RWSAMLVWILLLL---------CCSANV-VTEEQPPNTLIGSLASDQGLPDTGHL--YKLEVGAPYLRVDGKTGDIYTTENSIDRESLKDCRNLFEGD-PCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRD-SGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQ--LIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSS-PVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKD---NGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGD--VPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMS-QLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQ------LSVEPDNGKFMIQNGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVT--KPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHG---LFRISSE-GEITLAKEFTPKHIGLHRLVVKVKDKGTPPR 797 HSP 2 Score: 75.0998 bits (183), Expect = 3.939e-13 Identity = 93/358 (25.98%), Postives = 161/358 (44.97%), Query Frame = 2
Query: 422 VLVNDRNDFIDSL-TVNLQINDLNDNTPLFS-TIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSS---NKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDK---ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQ--TFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKK-ENLYSLAS------VRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHI 1441
V V+ N + S ++ +Q+ D+NDN P+FS T+ + E+ P + + + A D D S N +Y + S FE++ + +R+ S+LD E Y+ + A D+ + + +++ V D NDN P F N Y S+ EN S V V D D G+ V +++ N +IQ T+ I S I +R + Y+F + A D + P+ V + I V D N+ P + + + + T P + +++ D DIG+NS+ +DF ++ L+ ++S + F + + +K D G+PP+ T + LVHI
Sbjct: 473 VAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDV-VATDAD-SGTNAELTYSITGGSVPEGLFEINPNTG---EVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILST---ISFDRE----KESTYSFRLKAVDGG-DPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSE----------LDFNIVGGNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQT--TALVHI 805
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 264.233 bits (674), Expect = 2.167e-72 Identity = 237/786 (30.15%), Postives = 377/786 (47.96%), Query Frame = 2
Query: 65 LEVLKNRPNHSYSLIKPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLT-VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL---EDSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI----LSTNER--VEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQL---------LKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
+ +LK+RPN +K LW+F + V EE PN IG++ Y PD K + +L+++ GD+ T + ID E+L + N+ G+ CF++ +V + D + L ++I D+NDNTP F++ T+++ E+ + + +A DRD S N + SY+L ++ + F L + K PQ L + LD E R Y LT+K D + + L I + D NDN P F K Y+ + EN+ G V+ V A D D G + Y+ +D + + ++ ++G I ++ + F VVAKD N P+ + V IT+ D N+ PVI I L T++ + E+ + + ++VSD D G+N+ V C + + + FQL KKK Y L + + D+ES + + I DSG+PP S+ S+ V +TD+N+ +P F Q + EV EN N V++++ATD D + + YS+ D + F I+ SG I+ N VLDRE E F+ A D + T +++T+ D NDN P F + F+V ENM +G +T DADKG N+ + L+ + E + + G I + S DRE +YT + D G P ++ VT+ VLDENDN P + P+ I+ +Y +T + V V+A D D G N + Y I + P +F + ++GE+ L K +
Sbjct: 23 MSILKDRPNS----LKLAMKRTATACFLWLFFQLPILGSSTKVAYRVPEEQPPNILIGSLASDYGYPDSKHL--YKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGE-KCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRD-SGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQ--LIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGAN-PKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGD--VPFQLKQVSDTGSDSKKK---YFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRV-NTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIH------LSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKY-LTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFE---LFQISHNNGEVTLEKAI 780 HSP 2 Score: 154.066 bits (388), Expect = 3.075e-37 Identity = 131/450 (29.11%), Postives = 223/450 (49.56%), Query Frame = 2
Query: 1067 SDFNNPQKEKVPVEITVEDINNYYP-----VIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCEL----QTESKIDFQLLKKK-ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA-RKQEVQKIFSVSKEG-FIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP--NPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE 2329
+D +P + +I + DIN+ P VI + + ENT G L I +D D G+N + EL + + Q+ + + E L + D E +IK D G+P +++ + + I D N+ +P+F+++ YE L EN+ VLQ+ A D D A I YS + + +D +G I + + DRE + T+ F+ A D +P TA T++ +TI D NDN P+ FG++ + E++ + + +D D+G N+ V V+ + + ++V S SK+ F++T +LD E+ + YT+E+ D G P++++ ++ V+V D NDN P + + PE N + N+LVM V A D D+G N ++ Y I P P+++ +FS++ DSG+IR+ LD +Q E
Sbjct: 142 TDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITL-------SIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPI-DREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENN-----DINDLVMEVSATDADSGPNSQLHYSIL-PDPSARG-IFSINPDSGQIRVNTVLDREQRE 576
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 258.455 bits (659), Expect = 4.276e-71 Identity = 235/782 (30.05%), Postives = 374/782 (47.83%), Query Frame = 2
Query: 77 KNRPNHSYSLIKPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLT-VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL---EDSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI----LSTNER--VEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQL---------LKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
++RPN +K LW+F + V EE PN IG++ Y PD K + +L+++ GD+ T + ID E+L + N+ G+ CF++ +V + D + L ++I D+NDNTP F++ T+++ E+ + + +A DRD S N + SY+L ++ + F L + K PQ L + LD E R Y LT+K D + + L I + D NDN P F K Y+ + EN+ G V+ V A D D G + Y+ +D + + ++ ++G I ++ + F VVAKD N P+ + V IT+ D N+ PVI I L T++ + E+ + + ++VSD D G+N+ V C + + + FQL KKK Y L + + D+ES + + I DSG+PP S+ S+ V +TD+N+ +P F Q + EV EN N V++++ATD D + + YS+ D + F I+ SG I+ N VLDRE E F+ A D + T +++T+ D NDN P F + F+V ENM +G +T DADKG N+ + L+ + E + + G I + S DRE +YT + D G P ++ VT+ VLDENDN P + P+ I+ +Y +T + V V+A D D G N + Y I + P +F + ++GE+ L K +
Sbjct: 35 RDRPNS----LKLAMKRTATACFLWLFFQLPILGSSTKVAYRVPEEQPPNILIGSLASDYGYPDSKHL--YKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGE-KCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRD-SGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQ--LIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGAN-PKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGD--VPFQLKQVSDTGSDSKKK---YFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRV-NTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIH------LSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKY-LTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFE---LFQISHNNGEVTLEKAI 788 HSP 2 Score: 153.68 bits (387), Expect = 2.828e-37 Identity = 131/450 (29.11%), Postives = 223/450 (49.56%), Query Frame = 2
Query: 1067 SDFNNPQKEKVPVEITVEDINNYYP-----VIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCEL----QTESKIDFQLLKKK-ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA-RKQEVQKIFSVSKEG-FIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP--NPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE 2329
+D +P + +I + DIN+ P VI + + ENT G L I +D D G+N + EL + + Q+ + + E L + D E +IK D G+P +++ + + I D N+ +P+F+++ YE L EN+ VLQ+ A D D A I YS + + +D +G I + + DRE + T+ F+ A D +P TA T++ +TI D NDN P+ FG++ + E++ + + +D D+G N+ V V+ + + ++V S SK+ F++T +LD E+ + YT+E+ D G P++++ ++ V+V D NDN P + + PE N + N+LVM V A D D+G N ++ Y I P P+++ +FS++ DSG+IR+ LD +Q E
Sbjct: 150 TDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITL-------SIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPI-DREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENN-----DINDLVMEVSATDADSGPNSQLHYSIL-PDPSARG-IFSINPDSGQIRVNTVLDREQRE 584
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 258.84 bits (660), Expect = 4.408e-71 Identity = 235/782 (30.05%), Postives = 374/782 (47.83%), Query Frame = 2
Query: 77 KNRPNHSYSLIKPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLT-VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL---EDSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI----LSTNER--VEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQL---------LKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
++RPN +K LW+F + V EE PN IG++ Y PD K + +L+++ GD+ T + ID E+L + N+ G+ CF++ +V + D + L ++I D+NDNTP F++ T+++ E+ + + +A DRD S N + SY+L ++ + F L + K PQ L + LD E R Y LT+K D + + L I + D NDN P F K Y+ + EN+ G V+ V A D D G + Y+ +D + + ++ ++G I ++ + F VVAKD N P+ + V IT+ D N+ PVI I L T++ + E+ + + ++VSD D G+N+ V C + + + FQL KKK Y L + + D+ES + + I DSG+PP S+ S+ V +TD+N+ +P F Q + EV EN N V++++ATD D + + YS+ D + F I+ SG I+ N VLDRE E F+ A D + T +++T+ D NDN P F + F+V ENM +G +T DADKG N+ + L+ + E + + G I + S DRE +YT + D G P ++ VT+ VLDENDN P + P+ I+ +Y +T + V V+A D D G N + Y I + P +F + ++GE+ L K +
Sbjct: 35 RDRPNS----LKLAMKRTATACFLWLFFQLPILGSSTKVAYRVPEEQPPNILIGSLASDYGYPDSKHL--YKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGE-KCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRD-SGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQ--LIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGAN-PKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGD--VPFQLKQVSDTGSDSKKK---YFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRV-NTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIH------LSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKY-LTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFE---LFQISHNNGEVTLEKAI 788 HSP 2 Score: 154.066 bits (388), Expect = 2.620e-37 Identity = 131/450 (29.11%), Postives = 223/450 (49.56%), Query Frame = 2
Query: 1067 SDFNNPQKEKVPVEITVEDINNYYP-----VIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCEL----QTESKIDFQLLKKK-ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA-RKQEVQKIFSVSKEG-FIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP--NPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE 2329
+D +P + +I + DIN+ P VI + + ENT G L I +D D G+N + EL + + Q+ + + E L + D E +IK D G+P +++ + + I D N+ +P+F+++ YE L EN+ VLQ+ A D D A I YS + + +D +G I + + DRE + T+ F+ A D +P TA T++ +TI D NDN P+ FG++ + E++ + + +D D+G N+ V V+ + + ++V S SK+ F++T +LD E+ + YT+E+ D G P++++ ++ V+V D NDN P + + PE N + N+LVM V A D D+G N ++ Y I P P+++ +FS++ DSG+IR+ LD +Q E
Sbjct: 150 TDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITL-------SIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPI-DREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENN-----DINDLVMEVSATDADSGPNSQLHYSIL-PDPSARG-IFSINPDSGQIRVNTVLDREQRE 584
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 259.225 bits (661), Expect = 5.599e-71 Identity = 235/782 (30.05%), Postives = 374/782 (47.83%), Query Frame = 2
Query: 77 KNRPNHSYSLIKPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLT-VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL---EDSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI----LSTNER--VEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQL---------LKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
++RPN +K LW+F + V EE PN IG++ Y PD K + +L+++ GD+ T + ID E+L + N+ G+ CF++ +V + D + L ++I D+NDNTP F++ T+++ E+ + + +A DRD S N + SY+L ++ + F L + K PQ L + LD E R Y LT+K D + + L I + D NDN P F K Y+ + EN+ G V+ V A D D G + Y+ +D + + ++ ++G I ++ + F VVAKD N P+ + V IT+ D N+ PVI I L T++ + E+ + + ++VSD D G+N+ V C + + + FQL KKK Y L + + D+ES + + I DSG+PP S+ S+ V +TD+N+ +P F Q + EV EN N V++++ATD D + + YS+ D + F I+ SG I+ N VLDRE E F+ A D + T +++T+ D NDN P F + F+V ENM +G +T DADKG N+ + L+ + E + + G I + S DRE +YT + D G P ++ VT+ VLDENDN P + P+ I+ +Y +T + V V+A D D G N + Y I + P +F + ++GE+ L K +
Sbjct: 35 RDRPNS----LKLAMKRTATACFLWLFFQLPILGSSTKVAYRVPEEQPPNILIGSLASDYGYPDSKHL--YKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGE-KCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRD-SGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQ--LIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGAN-PKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGD--VPFQLKQVSDTGSDSKKK---YFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRV-NTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIH------LSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKY-LTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFE---LFQISHNNGEVTLEKAI 788 HSP 2 Score: 153.68 bits (387), Expect = 3.666e-37 Identity = 131/450 (29.11%), Postives = 223/450 (49.56%), Query Frame = 2
Query: 1067 SDFNNPQKEKVPVEITVEDINNYYP-----VIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCEL----QTESKIDFQLLKKK-ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA-RKQEVQKIFSVSKEG-FIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP--NPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE 2329
+D +P + +I + DIN+ P VI + + ENT G L I +D D G+N + EL + + Q+ + + E L + D E +IK D G+P +++ + + I D N+ +P+F+++ YE L EN+ VLQ+ A D D A I YS + + +D +G I + + DRE + T+ F+ A D +P TA T++ +TI D NDN P+ FG++ + E++ + + +D D+G N+ V V+ + + ++V S SK+ F++T +LD E+ + YT+E+ D G P++++ ++ V+V D NDN P + + PE N + N+LVM V A D D+G N ++ Y I P P+++ +FS++ DSG+IR+ LD +Q E
Sbjct: 150 TDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITL-------SIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPI-DREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENN-----DINDLVMEVSATDADSGPNSQLHYSIL-PDPSARG-IFSINPDSGQIRVNTVLDREQRE 584
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 258.84 bits (660), Expect = 1.500e-70 Identity = 235/782 (30.05%), Postives = 374/782 (47.83%), Query Frame = 2
Query: 77 KNRPNHSYSLIKPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLT-VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL---EDSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI----LSTNER--VEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQL---------LKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
++RPN +K LW+F + V EE PN IG++ Y PD K + +L+++ GD+ T + ID E+L + N+ G+ CF++ +V + D + L ++I D+NDNTP F++ T+++ E+ + + +A DRD S N + SY+L ++ + F L + K PQ L + LD E R Y LT+K D + + L I + D NDN P F K Y+ + EN+ G V+ V A D D G + Y+ +D + + ++ ++G I ++ + F VVAKD N P+ + V IT+ D N+ PVI I L T++ + E+ + + ++VSD D G+N+ V C + + + FQL KKK Y L + + D+ES + + I DSG+PP S+ S+ V +TD+N+ +P F Q + EV EN N V++++ATD D + + YS+ D + F I+ SG I+ N VLDRE E F+ A D + T +++T+ D NDN P F + F+V ENM +G +T DADKG N+ + L+ + E + + G I + S DRE +YT + D G P ++ VT+ VLDENDN P + P+ I+ +Y +T + V V+A D D G N + Y I + P +F + ++GE+ L K +
Sbjct: 35 RDRPNS----LKLAMKRTATACFLWLFFQLPILGSSTKVAYRVPEEQPPNILIGSLASDYGYPDSKHL--YKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGE-KCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRD-SGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQ--LIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGAN-PKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGD--VPFQLKQVSDTGSDSKKK---YFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRV-NTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIH------LSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKY-LTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFE---LFQISHNNGEVTLEKAI 788 HSP 2 Score: 153.68 bits (387), Expect = 4.258e-37 Identity = 131/450 (29.11%), Postives = 223/450 (49.56%), Query Frame = 2
Query: 1067 SDFNNPQKEKVPVEITVEDINNYYP-----VIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCEL----QTESKIDFQLLKKK-ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA-RKQEVQKIFSVSKEG-FIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP--NPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE 2329
+D +P + +I + DIN+ P VI + + ENT G L I +D D G+N + EL + + Q+ + + E L + D E +IK D G+P +++ + + I D N+ +P+F+++ YE L EN+ VLQ+ A D D A I YS + + +D +G I + + DRE + T+ F+ A D +P TA T++ +TI D NDN P+ FG++ + E++ + + +D D+G N+ V V+ + + ++V S SK+ F++T +LD E+ + YT+E+ D G P++++ ++ V+V D NDN P + + PE N + N+LVM V A D D+G N ++ Y I P P+++ +FS++ DSG+IR+ LD +Q E
Sbjct: 150 TDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITL-------SIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPI-DREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENN-----DINDLVMEVSATDADSGPNSQLHYSIL-PDPSARG-IFSINPDSGQIRVNTVLDREQRE 584
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 251.136 bits (640), Expect = 4.496e-68 Identity = 230/756 (30.42%), Postives = 350/756 (46.30%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQINDN-GDV-TLKKRIDLETLCQNSNICCGQFL---CFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN-ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
IF +L A F+ N TV+EE N IG++ L PDK + ++F + D ++I + G++ T RID E LC G L CF + +V V ++ + + I D+NDN PLF T I++ E+ +N SL +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN PIF + +VSI EN GS V ++A D D G+ + + + F +N+ +G I ++ L + + V+A D + P + V V +T DIN+ P I I TN V + EN L + I V D D N +V C T+ ++ F+L N + L + DFES + + + D+G PP + +L+ + D N+ +P F Q +S+ EN + ++ +++ATD D A I Y L F +D +G I T LDRE E F A D + P + + VT+ D+NDN+PIF F V E++ +G +T TD D G NS V +L +V F++ + G I S DRE ESYT V D G+ +++ VT+ V+D NDNKP +++P P N + + N +V V A D D G N + Y I + + +F +++ SG I L
Sbjct: 9 IFAVL--LACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLC------AGIVLDARCFYEVEVAVLP-DEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGI-NGVQNYQLIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGG-STPARATVLVNVT--DINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCF--TDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTG-ILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSIL-------DVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVG---GNTKGLFMIEQTSGNITL 735 HSP 2 Score: 72.4034 bits (176), Expect = 3.103e-12 Identity = 80/281 (28.47%), Postives = 120/281 (42.70%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQS-----------LDRETFESYTLEVGVRDKGKYPMATSTNV-TVKVLDENDNKPQWMNPNPINPEYNITRIINKN----ELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKP 2365
+I+ +G I T +DRE V++ F D KI IED NDNAP+F + ++ EN A D D G N + L+K+ Q IF + IET + LDRE ++Y ++V V D G +P +ST + V V D NDN P ++ E I I +N V + A D D GEN RI + N N + +F L+ +G I + + LD ++ +L ++A+D + P
Sbjct: 74 LIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKS-------QNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGG-FPQRSSTAILQVSVADTNDNHPIFI-------EKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTP 336
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 248.825 bits (634), Expect = 4.974e-68 Identity = 230/756 (30.42%), Postives = 350/756 (46.30%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQINDN-GDV-TLKKRIDLETLCQNSNICCGQFL---CFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN-ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
IF +L A F+ N TV+EE N IG++ L PDK + ++F + D ++I + G++ T RID E LC G L CF + +V V ++ + + I D+NDN PLF T I++ E+ +N SL +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN PIF + +VSI EN GS V ++A D D G+ + + + F +N+ +G I ++ L + + V+A D + P + V V +T DIN+ P I I TN V + EN L + I V D D N +V C T+ ++ F+L N + L + DFES + + + D+G PP + +L+ + D N+ +P F Q +S+ EN + ++ +++ATD D A I Y L F +D +G I T LDRE E F A D + P + + VT+ D+NDN+PIF F V E++ +G +T TD D G NS V +L +V F++ + G I S DRE ESYT V D G+ +++ VT+ V+D NDNKP +++P P N + + N +V V A D D G N + Y I + + +F +++ SG I L
Sbjct: 9 IFAVL--LACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLC------AGIVLDARCFYEVEVAVLP-DEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGI-NGVQNYQLIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGG-STPARATVLVNVT--DINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTC--FTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTG-ILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSIL-------DVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVG---GNTKGLFMIEQTSGNITL 735 HSP 2 Score: 71.633 bits (174), Expect = 4.373e-12 Identity = 78/277 (28.16%), Postives = 118/277 (42.60%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQS-----------LDRETFESYTLEVGVRDKGKYPMATSTNV-TVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKP 2365
+I+ +G I T +DRE V++ F D KI IED NDNAP+F + ++ EN A D D G N + L+K+ Q IF + IET + LDRE ++Y ++V V D G +P +ST + V V D NDN P ++ E +I V + A D D GEN RI + N N + +F L+ +G I + + LD ++ +L ++A+D + P
Sbjct: 74 LIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKS-------QNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGG-FPQRSSTAILQVSVADTNDNHPIFIEKEI---EVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTP 336
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 251.136 bits (640), Expect = 5.056e-68 Identity = 230/756 (30.42%), Postives = 350/756 (46.30%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQINDN-GDV-TLKKRIDLETLCQNSNICCGQFL---CFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN-ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
IF +L A F+ N TV+EE N IG++ L PDK + ++F + D ++I + G++ T RID E LC G L CF + +V V ++ + + I D+NDN PLF T I++ E+ +N SL +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN PIF + +VSI EN GS V ++A D D G+ + + + F +N+ +G I ++ L + + V+A D + P + V V +T DIN+ P I I TN V + EN L + I V D D N +V C T+ ++ F+L N + L + DFES + + + D+G PP + +L+ + D N+ +P F Q +S+ EN + ++ +++ATD D A I Y L F +D +G I T LDRE E F A D + P + + VT+ D+NDN+PIF F V E++ +G +T TD D G NS V +L +V F++ + G I S DRE ESYT V D G+ +++ VT+ V+D NDNKP +++P P N + + N +V V A D D G N + Y I + + +F +++ SG I L
Sbjct: 9 IFAVL--LACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLC------AGIVLDARCFYEVEVAVLP-DEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGI-NGVQNYQLIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGG-STPARATVLVNVT--DINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCF--TDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTG-ILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSIL-------DVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVG---GNTKGLFMIEQTSGNITL 735 HSP 2 Score: 71.633 bits (174), Expect = 5.414e-12 Identity = 80/281 (28.47%), Postives = 120/281 (42.70%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQS-----------LDRETFESYTLEVGVRDKGKYPMATSTNV-TVKVLDENDNKPQWMNPNPINPEYNITRIINKN----ELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKP 2365
+I+ +G I T +DRE V++ F D KI IED NDNAP+F + ++ EN A D D G N + L+K+ Q IF + IET + LDRE ++Y ++V V D G +P +ST + V V D NDN P ++ E I I +N V + A D D GEN RI + N N + +F L+ +G I + + LD ++ +L ++A+D + P
Sbjct: 74 LIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKS-------QNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGG-FPQRSSTAILQVSVADTNDNHPIFI-------EKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTP 336
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 249.98 bits (637), Expect = 5.397e-68 Identity = 230/756 (30.42%), Postives = 350/756 (46.30%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQINDN-GDV-TLKKRIDLETLCQNSNICCGQFL---CFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN-ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
IF +L A F+ N TV+EE N IG++ L PDK + ++F + D ++I + G++ T RID E LC G L CF + +V V ++ + + I D+NDN PLF T I++ E+ +N SL +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN PIF + +VSI EN GS V ++A D D G+ + + + F +N+ +G I ++ L + + V+A D + P + V V +T DIN+ P I I TN V + EN L + I V D D N +V C T+ ++ F+L N + L + DFES + + + D+G PP + +L+ + D N+ +P F Q +S+ EN + ++ +++ATD D A I Y L F +D +G I T LDRE E F A D + P + + VT+ D+NDN+PIF F V E++ +G +T TD D G NS V +L +V F++ + G I S DRE ESYT V D G+ +++ VT+ V+D NDNKP +++P P N + + N +V V A D D G N + Y I + + +F +++ SG I L
Sbjct: 9 IFAVL--LACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLC------AGIVLDARCFYEVEVAVLP-DEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGI-NGVQNYQLIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGG-STPARATVLVNVT--DINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTC--FTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTG-ILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSIL-------DVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVG---GNTKGLFMIEQTSGNITL 735 HSP 2 Score: 71.633 bits (174), Expect = 4.935e-12 Identity = 80/281 (28.47%), Postives = 120/281 (42.70%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQS-----------LDRETFESYTLEVGVRDKGKYPMATSTNV-TVKVLDENDNKPQWMNPNPINPEYNITRIINKN----ELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKP 2365
+I+ +G I T +DRE V++ F D KI IED NDNAP+F + ++ EN A D D G N + L+K+ Q IF + IET + LDRE ++Y ++V V D G +P +ST + V V D NDN P ++ E I I +N V + A D D GEN RI + N N + +F L+ +G I + + LD ++ +L ++A+D + P
Sbjct: 74 LIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKS-------QNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGG-FPQRSSTAILQVSVADTNDNHPIFI-------EKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTP 336
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 251.136 bits (640), Expect = 5.488e-68 Identity = 230/756 (30.42%), Postives = 350/756 (46.30%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQINDN-GDV-TLKKRIDLETLCQNSNICCGQFL---CFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN-ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
IF +L A F+ N TV+EE N IG++ L PDK + ++F + D ++I + G++ T RID E LC G L CF + +V V ++ + + I D+NDN PLF T I++ E+ +N SL +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN PIF + +VSI EN GS V ++A D D G+ + + + F +N+ +G I ++ L + + V+A D + P + V V +T DIN+ P I I TN V + EN L + I V D D N +V C T+ ++ F+L N + L + DFES + + + D+G PP + +L+ + D N+ +P F Q +S+ EN + ++ +++ATD D A I Y L F +D +G I T LDRE E F A D + P + + VT+ D+NDN+PIF F V E++ +G +T TD D G NS V +L +V F++ + G I S DRE ESYT V D G+ +++ VT+ V+D NDNKP +++P P N + + N +V V A D D G N + Y I + + +F +++ SG I L
Sbjct: 9 IFAVL--LACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLC------AGIVLDARCFYEVEVAVLP-DEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGI-NGVQNYQLIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGG-STPARATVLVNVT--DINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCF--TDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTG-ILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSIL-------DVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVG---GNTKGLFMIEQTSGNITL 735 HSP 2 Score: 71.633 bits (174), Expect = 5.481e-12 Identity = 80/281 (28.47%), Postives = 120/281 (42.70%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQS-----------LDRETFESYTLEVGVRDKGKYPMATSTNV-TVKVLDENDNKPQWMNPNPINPEYNITRIINKN----ELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKP 2365
+I+ +G I T +DRE V++ F D KI IED NDNAP+F + ++ EN A D D G N + L+K+ Q IF + IET + LDRE ++Y ++V V D G +P +ST + V V D NDN P ++ E I I +N V + A D D GEN RI + N N + +F L+ +G I + + LD ++ +L ++A+D + P
Sbjct: 74 LIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKS-------QNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGG-FPQRSSTAILQVSVADTNDNHPIFI-------EKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTP 336
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q9BZA8|PC11Y_HUMAN (Protocadherin-11 Y-linked OS=Homo sapiens OX=9606 GN=PCDH11Y PE=1 SV=1) HSP 1 Score: 256.529 bits (654), Expect = 5.119e-69 Identity = 228/788 (28.93%), Postives = 375/788 (47.59%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L + F N T++EE N IGN+ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++++++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F +F V EN+ +G +T TD D G+NS V +L + F++ S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 41 IFAVLLVCV--VFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-------DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 801
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q6WYY1|PC11X_PANPA (Protocadherin-11 X-linked OS=Pan paniscus OX=9597 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 254.988 bits (650), Expect = 1.836e-68 Identity = 228/788 (28.93%), Postives = 373/788 (47.34%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L A F N T++EE N IG++ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++ +++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F F V EN+ +G +T TD D G+NS V +L + F++ S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 9 IFAVL--LACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGT-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-------DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PSNYSYELVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q71M42|PC11X_PANTR (Protocadherin-11 X-linked OS=Pan troglodytes OX=9598 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 254.988 bits (650), Expect = 1.956e-68 Identity = 228/788 (28.93%), Postives = 373/788 (47.34%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L A F N T++EE N IG++ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++ +++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F F V EN+ +G +T TD D G+NS V +L + F++ S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 9 IFAVL--LACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGT-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-------DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PSNYSYELVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 254.603 bits (649), Expect = 2.430e-68 Identity = 228/788 (28.93%), Postives = 373/788 (47.34%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L A F N T++EE N IG++ L P+K ++++F + D ++I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++ +++ATD D A I Y L F +D +G + LDRE + +F A D V P T+ + V+I D+NDN+P+F F V EN+ +G +T TD D G+NS V +L + F++ S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 9 IFAVL--LACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNMFGLDVIETPEGDKMPQ--LIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVK-KLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-------DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PSNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q6WXV7|PC11X_PONPY (Protocadherin-11 X-linked OS=Pongo pygmaeus OX=9600 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 251.906 bits (642), Expect = 1.773e-67 Identity = 229/788 (29.06%), Postives = 373/788 (47.34%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYAL-----PDKLKFSSLKFNV-----DSQFLQIN-DNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT-RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIEL--TIIASDSATKPKMVMLKLIIN 2395
IF +L A F N T++EE N IG++ L P+K ++++F + D +I D G++ T RID E LC + I + CF + +V + ++ + + I D+NDN PLF I++ E+ +N +L +A D D N +++Y+L S N F LD K PQ L ++ ELD E + Y + +K D + L + V D NDN P+F + +VSI EN G+ V ++A D D G+ + ++ + F +N+ +G I ++ L + + V+A D P + V V +T D+N+ P I I N+ V + EN +P N + I V+D D N +V C T+ +I F+L N + L + D+ES + + + D+G PP + + + + D N+ +P F Q VS+ EN + ++ +++ATD D A I Y L F +D +G + T LDRE + +F A D V P T+ + V+I D+NDN+P+F F V EN+ +G +T TD D G+NS V +L + F++ S+ G I S DRE ESYT V D G+ ++S VT+ V+D NDNKP ++ P P N Y + N +V V A D D G N ++Y I + + +F++D+++G I L+++ D + L ++ ++ +P + +I+N
Sbjct: 9 IFAVL--LACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLTRIEEDTGEIFTTGARIDREKLC--AGIPRDEH-CFYEVEVAILP-DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQNIFGLDVIETPEGDKMPQ--LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM-PARAMVLVNVT--DVNDNVPSIDIRYIVNPINDTVVLSEN-IPLNTKIALITVTDKDADHNGRVTC--FTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGML-TVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-------DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVP-PSNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG---GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
BLAST of Protocadherin vs. TrEMBL
Match: W6UEM3 (Protocadherin OS=Echinococcus granulosus OX=6210 GN=EGR_08610 PE=4 SV=1) HSP 1 Score: 435.261 bits (1118), Expect = 2.629e-131 Identity = 272/766 (35.51%), Postives = 399/766 (52.09%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPDKLKFSSLK---------FNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLV---NDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD---SDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVE------VRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLD----EKGK--------------------AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDP-FTATTKIIVTIEDENDNAPIFGVIPE---------------FTVKENMIS-TRLIGRLTATDADKGNNSQVEFVL-----LKTLA--------------------RKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
N + EE + N IG+I+ +P +S K FNVDSQ +G+V +K +D E+LCQ CCG C + V V RN + + + +++ND+NDN P+F++ Q +++ E+ V S+ L A D D N++ Y+ +++ F LD + P I LRL S +D E R Y L ACD SCT +++I+++D NDN P K Y + I E+ GS ++ +NA D+DS + + Y+ P D DL+ TF I +N+GEIRL R L A R Y F V A D S+ + VE+ V+D+N+ P+I I+ E V V EN LPG++ ++V D DIG NS+ CEL +S F+L LYSL ++RSFDFE + + I+C D GSP S+ + + + I D+NEY PEF+ ++ S+ EN+ +V+ LNA DRDG + + YSL ++G A+F +D +G ++T V LDREVIE I DA +P FTAT + + + DENDN+P+F P FT++EN + L GRL A D D N Q++F L LK++A R+ Q+IF ++ +G IETL DRE Y L V VRD G P+ATST++ V++LDENDN P+W P + NIT LV +QAFD DA + G++++++
Sbjct: 2 NFEIHEETEVNSTIGSIRDVVP---TYSGTKTVFIYTGDFFNVDSQ------SGEVKVKTVLDRESLCQEHKQCCGTVNCTLTETVYVINAQTRN-LMTPMHLRVKVNDINDNKPIFASSIQRVSIPENSEVGKSIGLRPATDADVDPRNKVTRYQWSEATETFSLDQTSLPAIRLRLNSPVDREVRSNYSGVLSACDIHSCTSTDVLIEIEDVNDNLPQLYKRRYGLEISESLAVGSTILHMNATDRDSAENARIFYSFREPVDPDLVDTFEIVANTGEIRLRRPLDAKIRSSYEFSVTACDTVASECASNPTSNADVEVVVKDVNDNKPIIEIVPAGESVSSSDDLVVPENYLPGHIAVVRVKDADIGENSRTTCEL--DSHTTFELSHSAPGLYSLRTLRSFDFEQESILTTIIRCRDFGSPSLSSTQIITLRILDVNEYPPEFQMHEFKASVSENSPPGVEVISLNAVDRDGQSELSYSLAPPPLQQGASEDFYGVGSLPNTFETLGVNAYFDLDPKTGVLRTSRVQLDREVIERITLVVTVTDALTEPIFTATATVSIEVLDENDNSPVFVNPPANIGLPFDQNDLKSHTFTIRENAPRYSHLSGRLEARDPDADQNGQLQFSLRSVWALKSVAGSAGHSSGNIFDDLSGTSPGRQLVEQRIFQITPDGDIETLVEFDRELVAMYLLNVAVRDNGSQPLATSTSLLVRILDENDNAPEWTFPTESARQINITTASPPGSLVARLQAFDVDADDAGKVEFQV 755 HSP 2 Score: 70.0922 bits (170), Expect = 2.987e-8 Identity = 77/280 (27.50%), Postives = 114/280 (40.71%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGF----IETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD--------FDQIELTIIASDSATKP 2365
FF +D SG +K K V LDRE V T+ + +A + V + D NDN PIF I ++ EN + IG ATDAD ++V T + E + FS+ + + +DRE +Y+ GV TST+V +++ D NDN PQ I+ + ++ + A D D+ EN RI Y P F + ++GEIRL + LD F +AS+ A+ P
Sbjct: 38 FFNVDSQSGEVKVKTV-LDRESLCQEHKQCCGTVNCTLTETVYVINAQTRNLMTPMHLRVKVNDINDNKPIFASSIQRVSIPENSEVGKSIGLRPATDADVDPRNKV------TRYQWSEATETFSLDQTSLPAIRLRLNSPVDREVRSNYS---GVLSACDIHSCTSTDVLIEIEDVNDNLPQLYKRRY---GLEISESLAVGSTILHMNATDRDSAENARIFYSFREPVDPDLVDTFEIVANTGEIRLRRPLDAKIRSSYEFSVTACDTVASECASNP 304
BLAST of Protocadherin vs. TrEMBL
Match: A0A087VXD3 (Protocadherin 9 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000056500 PE=4 SV=1) HSP 1 Score: 438.728 bits (1127), Expect = 6.490e-131 Identity = 275/766 (35.90%), Postives = 398/766 (51.96%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPDKLKFSSLK---------FNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLV---NDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD---SDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVE------VRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLD----EKGK--------------------AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDP-FTATTKIIVTIEDENDNAPIFGVIPE---------------FTVKENMIS-TRLIGRLTATDADKGNNSQVEFVL-----LKTLA--------------------RKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
N + EE + N IG+I+ +P +S K FNVDSQ +G+V +K +D E+LCQ CCG C + V V RN F+ + + +++ND+NDN P+F++ Q +++ E+ V S+ L A D D N++ Y+ + + F LD + P I LRL S +D E R Y L ACD SCT +++I+++D NDN P K Y + I E+ GS ++ VNA D+DS + + Y+ P D DL+ TF I +N+GEIRL R L A R Y F V A D S+ + VE+ V+D+N+ P+I I+ E V V EN LPG + ++V D DIG NS+ CEL +S F+L LYSL ++RSFDFE + + I+C D GSP S+ + + + I D+NEY PEF+ ++ S+ EN+ +V+ LNA DRDG + + YSL ++G A+F +D +G ++T V LDREVIE I DA +P FTAT + + + DENDN+P+F P FTV+EN + L GRL A D D N Q++F L LK++A R+ Q+IF ++ +G IETL DRE Y L V VRD G P+ATST++ V++LDENDN P+W P + NIT LV +QAFD DA + G++++++
Sbjct: 23 NFEIHEETEVNSTIGSIRDVVP---TYSGTKTVFIYTGDFFNVDSQ------SGEVKVKTVLDRESLCQEHKQCCGTVNCTLTETVYVINAQTRN-FMTPVQLRVKVNDINDNKPIFASSIQRVSIPENSEVGKSIGLRPATDADVDPRNKVTRYQWSEVTETFSLDQTSLPAIRLRLNSPVDREVRSNYSGVLSACDIHSCTSTDVLIEIEDVNDNSPQLYKRRYGLEISESLAVGSTILHVNATDRDSAENARIFYSFREPVDPDLVDTFEIVANTGEIRLRRPLDAKIRSSYEFSVTACDTVASECASNPTSNADVEVVVKDVNDNKPIIEIVPAGESVSSSDDLVVPENYLPGQIAVVRVKDADIGENSRTTCEL--DSHTTFELSHSGTGLYSLRTLRSFDFEQESILTTIIRCRDFGSPSLSSTQIITLRIFDVNEYPPEFQMRKFKASVSENSPPGVEVISLNAVDRDGQSELSYSLAPPPLQQGARENLYGVESLPNTFETLSFNAYFDLDPKTGVLRTSRVQLDREVIERITLVVTVTDALTEPIFTATATVSIEVLDENDNSPVFVNPPPNIGLPFDQNDLQSHTFTVRENAPRYSHLSGRLEARDPDADQNGQLQFSLRSVWALKSVADSVGHSSGNIFDDLSGTSPGRQLVEQRIFQITPDGGIETLVEFDRELVAMYLLNVAVRDNGSQPLATSTSLLVRILDENDNAPEWTFPTESARQINITTASPPGSLVARLQAFDVDADDAGKVEFQV 776 HSP 2 Score: 77.0258 bits (188), Expect = 2.226e-10 Identity = 81/282 (28.72%), Postives = 118/282 (41.84%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGF----IETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN--ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD--------FDQIELTIIASDSATKP 2365
FF +D SG +K K VLDRE V T+ + +A F ++ V + D NDN PIF I ++ EN + IG ATDAD ++V T + EV + FS+ + + +DRE +Y+ GV TST+V +++ D NDN PQ Y I+ + ++ V A D D+ EN RI Y P F + ++GEIRL + LD F +AS+ A+ P
Sbjct: 59 FFNVDSQSGEVKVK-TVLDRESLCQEHKQCCGTVNCTLTETVYVINAQTRNFMTPVQLRVKVNDINDNKPIFASSIQRVSIPENSEVGKSIGLRPATDADVDPRNKV------TRYQWSEVTETFSLDQTSLPAIRLRLNSPVDREVRSNYS---GVLSACDIHSCTSTDVLIEIEDVNDNSPQLYKR-----RYGLEISESLAVGSTILHVNATDRDSAENARIFYSFREPVDPDLVDTFEIVANTGEIRLRRPLDAKIRSSYEFSVTACDTVASECASNP 325
BLAST of Protocadherin vs. TrEMBL
Match: A0A5K3FHZ7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 439.113 bits (1128), Expect = 8.540e-131 Identity = 275/790 (34.81%), Postives = 409/790 (51.77%), Query Frame = 2
Query: 134 IFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQIN-DNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLV--NDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD---SDFNNPQKEKVPVEITVEDINNYYPVIAIL------STNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKID-FQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL------DEKGK---------------------AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDP-FTATTKIIVTIEDENDNAPIFGVIP---------------EFTVKENMIS-TRLIGRLTATDADKGNNSQVEFVL----------------------LKTLARKQEV-QKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPV 2263
+ IL + + E N TA+ ++EE + N IG+++ L S + F F +I+ G+V + +D ET+CQ ICCG C + KV + + D+I ++ + + + D+NDN P+F + Q + + E+ V + L SA D D + +N++ Y+ + + F LD + P I LRL S +D E R Y TL ACD DSCT ++ I+V+D NDN P F K Y++ E+ GS ++ +NA D DSGD ++Y+ P D DL TF I +NSGE+RL R L A R Y F VVA D S+ +E+ V+D+N+ PVI I+ S+ + V+EN G + +KV D DIG NS+ CEL + F L + +LY L ++RSFDFE V + +I+C D G+PP S+ R++ + + D+NEY+PEF Q ++ S+REN+ ++ L+A DRDG + +RY L +G+ F +D +G ++T V LDREVIE I D+ P FTAT + + + DENDN+P+F P FTV+EN TRL GRL A D D G N Q+ F L +++ +Q V Q++F ++ + IETL DRE Y ++V VRD G P+ATST++ V +LDENDN P W P + + NIT LV +QAFD DA E G++++++ +P PV
Sbjct: 10 LIFILPLLTSAEHGTNQRTASFEMQEETELNTTIGSLRENL-SPYPGSKVAFMYSGDFFRIDCHTGEVKVAVVLDRETVCQEHKICCGVIDCTLVDKVYLVYAESRDYIATILLKVDLTDINDNRPVFGSHLQRVNILENSEVGRYIGLRSATDADVNPKNQVNRYQWIEPTGTFILDQNNLPSIRLRLNSPVDREMRANYSGTLSACDIDSCTTTDVFIEVEDVNDNSPQFYKRHYRLESPESLTVGSTILRLNATDADSGDNAKIVYSFREPVDPDLADTFEIIANSGELRLRRPLDAKIRSSYNFKVVACDSVASECAGNDASSADIEVVVKDVNDNRPVIEIIPAGDYTSSTGDLVVQENFPAGQIAVVKVKDADIGENSRTACELDDHTSPSVFDLSQSAPDLYFLRTMRSFDFEQESVLTTTIRCRDFGTPPLSSVRTLTLRVLDVNEYAPEFHQRVFSTSVRENSQPGVDIITLSAIDRDGQSELRYKLAPPPLQHAEGEDIYSTAVSPSSTNSVETMGVNVHFDLDPKTGVLRTSRVQLDREVIERITLVVTVTDSSTPPIFTATATVSIEVLDENDNSPVFLSPPANMGFPFHQNDIQSYAFTVRENAPRYTRLSGRLEARDPDAGRNGQLHFSLRSVWALKGASGSYRHPGSGFNDMRSTPGRQLVEQRVFQITPDNGIETLIEFDREQVGMYLVDVAVRDNGTQPLATSTSLLVLILDENDNAPVWTFPADSSRQINITTADLPGTLVARLQAFDIDADEAGKVEFQVLDPNGQPMPPV 798 HSP 2 Score: 87.8113 bits (216), Expect = 1.192e-13 Identity = 126/535 (23.55%), Postives = 223/535 (41.68%), Query Frame = 2
Query: 971 FGINSNSGEIR----LERRLAANQRKLY-----------TFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIK-VSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYS----LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTA----TTKIIVTIEDENDNAPIFGVIP---------EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEG----FIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNEL----VMTVQAFDTDAGENGRIKYRIHNP---------------KPNSKQPV--------FSLDEDSGEIRLVK-ELD---FDQIELTIIASDSATKP 2365
F I+ ++GE++ L+R + K+ + V A+ D+ + +++ + DIN+ PV S +RV + EN+ G I ++ +D D+ ++VN E F L + L D E S ++ D S T V + + D+N+ SP+F + Y + E+ + +L+LNATD D A I YS +D F+I SG ++ + LD ++ + F A D+ + I V ++D NDN P+ +IP + V+EN + + I + DAD G NS+ L +F +S+ F+ T++S D E T + RD G P+++ +T++VLD N+ P++ + + + +N ++T+ A D D ++Y++ P P+S V F LD +G +R + +LD ++I L + +DS+T P
Sbjct: 67 FRIDCHTGEVKVAVVLDRETVCQEHKICCGVIDCTLVDKVYLVYAESRDY----IATILLKVDLTDINDNRPVFG--SHLQRVNILENSEVGRYIGLRSATDADVNPKNQVNRYQWIEPTGTFILDQNNLPSIRLRLNSPVDREMRANYSGTLSACDIDS---CTTTDVFIEVEDVNDNSPQFYKRHYRLESPESLTVGSTILRLNATDADSGDNAKIVYSFREPVDPDLADTFEIIANSGELRLRRP-LDAKIRSSYNFKVVACDSVASECAGNDASSADIEVVVKDVNDNRPVIEIIPAGDYTSSTGDLVVQENFPAGQ-IAVVKVKDADIGENSRTACEL-----DDHTSPSVFDLSQSAPDLYFLRTMRSFDFEQESVLTTTIRCRDFGTPPLSSVRTLTLRVLDVNEYAPEFH-------QRVFSTSVRENSQPGVDIITLSAIDRDG--QSELRYKLAPPPLQHAEGEDIYSTAVSPSSTNSVETMGVNVHFDLDPKTGVLRTSRVQLDREVIERITLVVTVTDSSTPP 576 HSP 3 Score: 68.5514 bits (166), Expect = 8.761e-8 Identity = 81/297 (27.27%), Postives = 133/297 (44.78%), Query Frame = 2
Query: 1496 LRENTATNTKV--LQLNATDRDGA-ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIE------------TIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFS-VSKEGFIETLQ-----SLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNI--TRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
++E T NT + L+ N + G+ + YS D FF+ID +G +K VVLDRE + T+V + A + AT + V + D NDN P+FG + + EN R IG +ATDAD +QV R Q ++ + + + + +++ +DRE +Y+ + D T+T+V ++V D NDN PQ+ + Y + + ++ + A D D+G+N +I Y P F + +SGE+RL + LD
Sbjct: 33 MQEETELNTTIGSLRENLSPYPGSKVAFMYSGD-----FFRIDCHTGEVKVA-VVLDRETVCQEHKICCGVIDCTLVDKVYLVYAESRDYIATILLKVDLTDINDNRPVFGSHLQRVNILENSEVGRYIGLRSATDADVNPKNQVN--------RYQWIEPTGTFILDQNNLPSIRLRLNSPVDREMRANYSGTLSACDIDS---CTTTDVFIEVEDVNDNSPQFYKRH-----YRLESPESLTVGSTILRLNATDADSGDNAKIVYSFREPVDPDLADTFEIIANSGELRLRRPLD 307
BLAST of Protocadherin vs. TrEMBL
Match: A0A068WWV1 (Protocadherin 9 OS=Echinococcus granulosus OX=6210 GN=EgrG_000056500 PE=4 SV=1) HSP 1 Score: 437.187 bits (1123), Expect = 2.313e-130 Identity = 275/789 (34.85%), Postives = 406/789 (51.46%), Query Frame = 2
Query: 125 MMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLK---------FNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLV---NDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD---SDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVE------VRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLD----EKGK--------------------AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDP-FTATTKIIVTIEDENDNAPIFGVIPE---------------FTVKENMIS-TRLIGRLTATDADKGNNSQVEFVL-----LKTLA--------------------RKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
M+ F +L + + N + EE + N IG+I+ +P +S K FNVDSQ +G+V +K +D E+LCQ CCG C + V V RN + + + +++ND+NDN P+F++ Q +++ E+ V S+ L A D D N++ Y+ +++ F LD + P I LRL S +D E R Y L ACD SCT +++I+++D NDN P K Y + I E+ GS ++ +NA D+DS + + Y+ P D DL+ TF I +N+GEIRL R L A R Y F V A D S+ ++ VE+ V+D+N+ P+I I+ E V V EN LPG + ++V D DIG NS+ CEL +S F+L LYSL ++RSFDFE + + I+C D GSP S+ + + + I D+NEY PEF+ ++ S+ EN+ +V+ LNA DRDG + + YSL ++G A+F +D +G ++T V LDREVIE I DA +P FTAT + + + DENDN+P+F P FT++EN + L GRL A D D N Q++F L LK++A R+ Q+IF ++ +G IETL DRE Y L V VRD G P+ATST++ V++LDENDN P+W P + NIT LV +QAFD DA + G++++++
Sbjct: 1 MLKNFAVLLLLTAVHASSQI-SMNFEIHEETEVNSTIGSIRDVVP---TYSGTKTVFIYTGDFFNVDSQ------SGEVKVKTVLDRESLCQEHKQCCGTVNCTLTETVYVINAQTRN-LMTPMHLRVKVNDINDNKPIFASSIQRVSIPENSEVGKSIGLRPATDADVDPRNKVTRYQWSEATETFSLDQTSLPAIRLRLNSPVDREVRSNYSGVLSACDIHSCTSTDVLIEIEDVNDNLPQLYKRRYGLEISESLAVGSTILHMNATDRDSAENARIFYSFREPVDPDLVDTFEIVANTGEIRLRRPLDAKIRSSYEFSVTACDTVASECSSNPTSNADVEVVVKDVNDNKPIIEIVPAGESVSSSDDLVVPENYLPGQIAVVRVKDADIGENSRTTCEL--DSHTTFELSHSAPGLYSLQTLRSFDFEQESILTTIIRCRDFGSPSLSSTQIITLRILDVNEYPPEFQMHEFKASVSENSPPGVEVISLNAVDRDGQSELSYSLAPPPLQQGASEDFYGVGSLPNTFETLGVNAYFDLDPKTGVLRTSRVQLDREVIERITLVVTVTDALTEPIFTATATVSIEVLDENDNSPVFVNPPANIGLPFDQNDLKSHTFTIRENAPRYSHLSGRLEARDPDADQNGQLQFSLRSVWALKSVAGSAGHSSGNIFDDLSGTSPGRQLVEQRIFQITPDGDIETLVEFDRELVAMYLLNVAVRDNGSQPLATSTSLLVRILDENDNAPEWTFPTESARQINITTASPPGSLVARLQAFDVDADDAGKVEFQV 776 HSP 2 Score: 69.707 bits (169), Expect = 4.697e-8 Identity = 76/273 (27.84%), Postives = 113/273 (41.39%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDRE------------VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGF----IETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN--ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIASDS 2353
FF +D SG +K K VLDRE V T+ + +A + V + D NDN PIF I ++ EN + IG ATDAD ++V T + E + FS+ + + +DRE +Y+ GV TST+V +++ D NDN PQ Y I+ + ++ + A D D+ EN RI Y P F + ++GEIRL + LD E ++ A D+
Sbjct: 59 FFNVDSQSGEVKVK-TVLDRESLCQEHKQCCGTVNCTLTETVYVINAQTRNLMTPMHLRVKVNDINDNKPIFASSIQRVSIPENSEVGKSIGLRPATDADVDPRNKV------TRYQWSEATETFSLDQTSLPAIRLRLNSPVDREVRSNYS---GVLSACDIHSCTSTDVLIEIEDVNDNLPQLYKR-----RYGLEISESLAVGSTILHMNATDRDSAENARIFYSFREPVDPDLVDTFEIVANTGEIRLRRPLDAKIRSSYEFSVTACDT 316
BLAST of Protocadherin vs. TrEMBL
Match: A0A0X3P764 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR84737 PE=4 SV=1) HSP 1 Score: 430.639 bits (1106), Expect = 6.013e-127 Identity = 270/781 (34.57%), Postives = 399/781 (51.09%), Query Frame = 2
Query: 197 LTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDN-GDVTLKKRIDLETLCQNSNICCGQFLCFIQTK--VLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD-------SDFNNPQKEKVPVEITVEDINNYYPVIAIL--------------STNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL---------------------DEKGKA--------FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDP-FTATTKIIVTIEDENDNAPIFGVIP---------------EFTVKENMIS-TRLIGRLTATDADKGNNSQVEFVLLKTLARKQEV----------------------QKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPV 2263
L + EE N IG++ +LP L + L + V +++ + + G V + + +D E++CQ + +CCG C Q V+ + ++ + S+ + + + D+NDN P F Q ++ E+ P+ L A D D NRI+ Y+L + ++ F LD S P I LR LD E Y L+ACDRDSC +L I+++DENDN P F ++ Y S+LE+ GS+++ +NA D DSG+ V+Y++ D DL +TF + +N+GE+RL R L A R Y F VVA D +D N+ + V TV+DIN++ P+I ++ S + + V EN+ PG + IKV D D+G N++ CEL E+ +F L + +LY+L + R FD+E + + +IKC DSGSPP+S+ R V + I D+NE+ P F + V + EN+ ++ +L ATD+DG + +RYSL D G A F +D SG+++T + LDRE ++ I A DA +TAT I V + DENDN+P+F P F V+EN TRL GRL A D D G N QV F L T A K Q+IF ++ +G IETL LDRE+ SY L V VRD G P+A++ + V VLDENDN P W P + NIT LV +QA+D DA G ++++I +P P+
Sbjct: 27 LDMTEETPVNTIIGSLTESLP-VLTGNKLNYLVSHTYVKADPHTGRVQVARVVDRESICQENKLCCGVIACSFQVTGYVVYANPSELMASVNLTINVIDINDNPPTFGAPMQKVSFPENSPIGRLQPLRPATDADIDPTNRIQRYRLTEPTDTFTLDQSHLPAIRLRSTRSLDREHVANYSAVLEACDRDSCAKSQLFIEIEDENDNSPQFERSQYSESLLEDIPVGSVILRLNATDADSGERAQVVYSLHESADPDLAETFEV-ANNGEVRLRRPLDAQVRSEYRFRVVACDMVAPICSADANSTAE----VIFTVQDINDHRPIIEVVPAVSFSGYVFGGDHSPQDGLSVPENSPPGQVAMIKVKDRDVGENARTFCEL-GETTNNFVLTQSSSSLYTLRTSRVFDYEREAIVTTTIKCRDSGSPPQSSFRVVTLRILDVNEFPPVFSPQVLHVQVSENSPAGLEIAKLTATDQDGQSHLRYSLLPIPHTGPTYDSNSDLGSAASDSYGDAGSNSGINRHFLLDPNSGFLRTSRIPLDRETVDRITLIATVTDATKGKIYTATATISVEVLDENDNSPVFVNPPANMGPSFPQDTIDSYAFNVRENSPPYTRLSGRLEARDPDAGQNGQVHFSLRSTWALKGGTQVHRSGFALDDLAGAPGRQLLDQRIFQITPDGGIETLVELDRESVSSYLLNVAVRDNGSQPLASTAMLLVLVLDENDNPPVWTFPTESARQINITTANQPGTLVARLQAYDIDADAAGTVEFQILDPHGQPMPPI 800 HSP 2 Score: 62.3882 bits (150), Expect = 7.384e-6 Identity = 65/259 (25.10%), Postives = 113/259 (43.63%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDREVIE----------TIVFNAFAHDAYVDP--FTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGF----IETLQSLDRETFESYT--LEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRI--INKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
+ K D +G ++ VV DRE I F + Y +P A+ + + + D NDN P FG + + + EN RL ATDAD ++++ R E F++ + + + +SLDRE +Y+ LE RD + + +++ DENDN PQ+ +Y+ + + I +++ + A D D+GE ++ Y +H F + ++GE+RL + LD
Sbjct: 62 YVKADPHTGRVQVARVV-DRESICQENKLCCGVIACSFQVTGYVVYANPSELMASVNLTINVIDINDNPPTFGAPMQKVSFPENSPIGRLQPLRPATDADIDPTNRIQRY------RLTEPTDTFTLDQSHLPAIRLRSTRSLDREHVANYSAVLEACDRDS-----CAKSQLFIEIEDENDNSPQFERS-----QYSESLLEDIPVGSVILRLNATDADSGERAQVVYSLHESADPDLAETFEV-ANNGEVRLRRPLD 302
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 249.98 bits (637), Expect = 6.010e-68 Identity = 226/767 (29.47%), Postives = 357/767 (46.54%), Query Frame = 2
Query: 137 FLILW--IFANFEFRVNCWTANLT--VKEEFKPNQFIGNIKY--ALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETL--CQNSNICCGQFLCFIQTKVLVND--RNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE---DSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDSCT---DKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVE------VRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENL------YSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEY-NITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
F + W +FA +N + V+EE PN IG++ LPD K V + +L+++ G++ T + ID ETL C+ C F++ +V V D +N + +++ D+NDNTP F + T++++E+ + + ++ A DRD + N + Y L ++S F L + K PQ L + LD E + Y LT+ A D + + L + + D NDN P F K+ Y+ + EN+ G V+ V A D D G G + Y I +D + + I ++G I ++ L + + FHV+A+D +P+ V I V D N+ P + I R + E+ G + ++VSD D G N+ V C + + + FQL ++ Y L + D+E + I DSG+P S+ S+ V +TD N+ SP F ++EV E KVL + A D D A + YS+ D + F+ID SG ++ ++ LDRE E F A D V T +++ + D NDN P F + F+V ENM +G +T D DKG N+QV+ L+ + +V + G I + S DRE SYT + D G+ P ++ VT+ VLDENDN P P+ N + ++ + + +V V+A D D G N + Y I P+ +F + GEI+L KEL
Sbjct: 39 FSVGWFLLFALLVDSINSALGGILYHVREEQPPNTLIGSLAADQGLPDSGHL--YKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKDCRIKGKPC-----FLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRD-TERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQ--LIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASD-PVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKG-PSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGD--VPFQLRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARS-PLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQ------LSVEPDVGNFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPS--NSSFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHE---LFYISPSDGEIKLTKEL 779
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 248.054 bits (632), Expect = 7.492e-68 Identity = 230/770 (29.87%), Postives = 360/770 (46.75%), Query Frame = 2
Query: 137 FLILW--IFANFEFRVNCWTANLT--VKEEFKPNQFIGNIKY--ALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETL--CQNSNICCGQFLCFIQTKVLVND--RNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE---DSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDSCT---DKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVE------VRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLL---------KKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEY-NITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
F + W +FA +N + V+EE PN IG++ LPD K V + +L+++ G++ T + ID ETL C+ G+ CF++ +V V D +N + +++ D+NDNTP F + T++++E+ + + ++ A DRD + N + Y L ++S F L + K PQ L + LD E + Y LT+ A D + + L + + D NDN P F K+ Y+ + EN+ G V+ V A D D G G + Y I +D + + I ++G I ++ L + + FHV+A+D +P+ V I V D N+ P + I R + E+ G + ++VSD D G N+ V C + + + FQL KKK Y L + D+E + I DSG+P S+ S+ V +TD N+ SP F ++EV E KVL + A D D A + YS+ D + F+ID SG ++ ++ LDRE E F A D V T +++ + D NDN P F + F+V ENM +G +T D DKG N+QV+ L+ + +V + G I + S DRE SYT + D G+ P ++ VT+ VLDENDN P P+ N + ++ + + +V V+A D D G N + Y I P+ +F + GEI+L KEL
Sbjct: 3 FSVGWFLLFALLVDSINSALGGILYHVREEQPPNTLIGSLAADQGLPDSGHL--YKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKDCR----IKGK-PCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRD-TERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQ--LIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASD-PVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKG-PSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGD--VPFQLRPAGDSSVDNKKK---YFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARS-PLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQ------LSVEPDVGNFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPS--NSSFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHE---LFYISPSDGEIKLTKEL 743
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh1b (protocadherin 1b [Source:ZFIN;Acc:ZDB-GENE-091015-2]) HSP 1 Score: 248.054 bits (632), Expect = 9.236e-68 Identity = 233/741 (31.44%), Postives = 344/741 (46.42%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKY--ALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVND--RNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL---EDSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE--KVPVEITVEDINNYYPVIAI----LSTNER--VEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKK------ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITR-IINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
++EE PN +G++ LPD K V +L+++ GD+ T ID ETL N+ G CF++ +V + D + + ++I D NDNTP F + + + E+ V S+ A D+D + N I YKL D+ N F L + K PQ L + LD E R Y L++K D + + L I + D NDN P F ++ Y+ + ENT G V+ V A D D G G V Y+ P+ ++ + I+ N+G I+++ + + L F V A+D N PQ + K V ITV+D N+ P I I L +E V E+ G + ++VSD D G N+ V C + + + FQL + Y L + D+E + I DSG+P S+ S+ V +TDMN+ +P F +YEV E KVL + ATD D A + YS+ D K F I+ +G ++ N LDRE E F+ A D V T ++V + D NDN P F + F+V ENM +G +T DADKG N+ V+ L+ + E K + G I + S DRE +YT + D G P ++ +T+ VLDENDN P P+ N Y + + + + V V A D D G N + Y I P+ +F + GEI L KE
Sbjct: 39 LREEQPPNTLVGSLAADQGLPDTGHL--YKLEVGGPYLRVDGKTGDIYTTDVPIDRETLKDCRNLFEGD-PCFLEFEVSITDLMKGSGPRLIEGRIEIQDENDNTPQFPSPILELAIPENTYVGAHYSIPVAMDKD-AGSNGIADYKLNSGSDAMNLFSLQVADNTDEKVPQ--LIVLGNLDREQRDTYDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSFHQPSP-NVQRLLHIDHNTGIIQVKGSVDREEVPLLKFSVQARD---NGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGD--VPFQLRSASASDSTSKRKYFLQTTTPLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLDVVATDADSGTNAELLYSIITDSATKGLFDINPNTGEVRVMN-QLDREYKERYEFHVEAADKGVPSLKGTATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSPVGMVTVIDADKGENAHVQ------LSVEPENGKFVIQNGTGTILSSISFDREKESTYTFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPS--NSSYKFLQPLTSPDTRVEKVDAEDIDTGLNAELVYSITGGNPHG---LFRISSTDGEITLAKEF 755 HSP 2 Score: 126.331 bits (316), Expect = 5.121e-29 Identity = 111/403 (27.54%), Postives = 191/403 (47.39%), Query Frame = 2
Query: 1172 VEVRENTLPGNLITIKVS-DNDIGMNSKVNCELQTESK----IDFQLLKKK-ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA-RKQEVQKIFSVSKEG-FIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
+ + ENT G +I V+ D D G N + +L + S Q+ E + L + + D E SIK D G+PP+ + + + ITD N+ P+F++ YE + ENT VLQ+ A D D A+ + YS + + IDH +G I+ K V DRE + + F+ A D ++ + +T++D NDNAP FG++ V E+M + + +D D+G N+ V V+ + + + S SK F++T LD E + Y +E+ D G ++++ ++ V+V D NDN P + +P E + + V+ V A D D+G N + Y I ++ + +F ++ ++GE+R++ +LD
Sbjct: 150 LAIPENTYVGAHYSIPVAMDKDAGSNGIADYKLNSGSDAMNLFSLQVADNTDEKVPQLIVLGNLDREQRDTYDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSFHQPSPNVQRLLHIDHNTGIIQVKGSV-DREEVPLLKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASASDSTSKRKYFLQTTTPLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVF---SPSLYEVDFAEENQPGDKVLDVVATDADSGTNAELLYSIITD--SATKGLFDINPNTGEVRVMNQLD 546
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 242.662 bits (618), Expect = 7.099e-66 Identity = 219/743 (29.48%), Postives = 346/743 (46.57%), Query Frame = 2
Query: 182 CWTA--NLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKK-------------RIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVI----AILSTNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRI-INKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
CW + TVKEE N IGN++ L L ++K + QF + GDV L + RID E LC + CF + +V V ++ + + I D+NDN PLF + I++ E+ +N + SAFD D N I+ Y+L S ++F LD K+PQ L ++ LD ET+ + + +K D + + L + V D NDN+P+F + +V++ EN G+ V ++A D D G + ++ + F I+S++G I +++ L ++ V+A D P + V V +T D+N+ P I + N V + EN L + I V+D D +N KV C T+ + F+L + + L + D+E+ + + I +DSG PP +T VL+ I D N+ +P F Q ++S+ EN T+++++ ATD D A I YSL F ID SG + LDRE E F A D +P + + + ++D+NDN+P F F V EN+ +G +T TDAD G+N+ V TL+ K G I+ + DRE SYT V D G + VT+ V+D NDN+P ++ P+ N Y++ N +V V A D D G N ++Y I P +F++D+ +G I L +++
Sbjct: 61 CWAQEKDYTVKEEQPENVRIGNLRTDLDLNLD-PNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLCSG---VFNEKRCFYEIEVAVLP-DEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGI-NGIQHYELVKSVSEFGLDIIETPEGDKWPQ--LIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGS-ATPSRATVIVNVT--DVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTC--YTDHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSK-RLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIV------TLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSS-NYSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRG---LFAIDKTTGNITLQEKI 779 HSP 2 Score: 72.4034 bits (176), Expect = 2.031e-12 Identity = 70/266 (26.32%), Postives = 123/266 (46.24%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDREVIETIVFNA----FAHDAYVDP--FTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLAR-KQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKP 2365
+++ +G I T +DRE + + VFN + + V P KI IED NDNAP+F + ++ EN +A D D G N + L+K+++ ++ + K + Q+LDRET +++ +++ V D G P +++ + V V D NDN+P + + E N+ V + A D D G N +I + N + + F++D +G I + + LD + +L ++ASD + P
Sbjct: 114 LVRVEASTGEIFTTANRIDRERLCSGVFNEKRCFYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEV---EVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATP 376
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 241.891 bits (616), Expect = 3.394e-65 Identity = 219/743 (29.48%), Postives = 346/743 (46.57%), Query Frame = 2
Query: 182 CWTA--NLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKK-------------RIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVI----AILSTNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRI-INKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
CW + TVKEE N IGN++ L L ++K + QF + GDV L + RID E LC + CF + +V V ++ + + I D+NDN PLF + I++ E+ +N + SAFD D N I+ Y+L S ++F LD K+PQ L ++ LD ET+ + + +K D + + L + V D NDN+P+F + +V++ EN G+ V ++A D D G + ++ + F I+S++G I +++ L ++ V+A D P + V V +T D+N+ P I + N V + EN L + I V+D D +N KV C T+ + F+L + + L + D+E+ + + I +DSG PP +T VL+ I D N+ +P F Q ++S+ EN T+++++ ATD D A I YSL F ID SG + LDRE E F A D +P + + + ++D+NDN+P F F V EN+ +G +T TDAD G+N+ V TL+ K G I+ + DRE SYT V D G + VT+ V+D NDN+P ++ P+ N Y++ N +V V A D D G N ++Y I P +F++D+ +G I L +++
Sbjct: 61 CWAQEKDYTVKEEQPENVRIGNLRTDLDLNLD-PNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLCSG---VFNEKRCFYEIEVAVLP-DEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGI-NGIQHYELVKSVSEFGLDIIETPEGDKWPQ--LIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGS-ATPSRATVIVNVT--DVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTC--YTDHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSK-RLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIV------TLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSS-NYSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRG---LFAIDKTTGNITLQEKI 779 HSP 2 Score: 72.7886 bits (177), Expect = 1.910e-12 Identity = 70/266 (26.32%), Postives = 123/266 (46.24%), Query Frame = 2
Query: 1601 FFKIDHMSGWIKTKNVVLDREVIETIVFNA----FAHDAYVDP--FTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLAR-KQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKP 2365
+++ +G I T +DRE + + VFN + + V P KI IED NDNAP+F + ++ EN +A D D G N + L+K+++ ++ + K + Q+LDRET +++ +++ V D G P +++ + V V D NDN+P + + E N+ V + A D D G N +I + N + + F++D +G I + + LD + +L ++ASD + P
Sbjct: 114 LVRVEASTGEIFTTANRIDRERLCSGVFNEKRCFYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEV---EVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATP 376
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 218.394 bits (555), Expect = 6.525e-59 Identity = 211/752 (28.06%), Postives = 328/752 (43.62%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLK------------KRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSS----NKFELDTS------KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLI-----QTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEI------------TVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLK-KKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDR--DGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYN--ITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
V EE + FIGN L +L +L+ + D ++ +++D E LC + + +Q VL F + V + + D+NDN P F+ T+++ E+ P ++ A D D S N + Y+L S + FEL + K P + +R LD E R+ Y + L+A D S L I+V D NDN P+F + V I EN+ G+ VV ++A D+D+G V+Y + + F ++ NSG + + L + +Y ++A D P+ + T+E + PV ++ +E V LP LIT VSD DIG N V C + ++ FQL K N Y L + + D+E+ IK D+G+ S SV + + D N+ +P F + Y+VS+ EN ++ ++ATDR D A + Y L F +D +G I LDRE F A D + +IV + D NDN P F + +F V EN+ +G +T D+D+G N +V +L T R ++FS+ E G I + DRE Y LEV D G+ +++ V + V+D NDN P + P P N Y + R + +V V A D DA N ++Y I P++ +F +D G I L++ L
Sbjct: 43 VAEELREGAFIGNPSVDL--RLADYNLELTYKVMLSKAEDAAPPLVRVNPRTGELFAAGRKMDREALCGGQD-PGDECHVDVQVGVLPVQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPD-SEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVR--KSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATD---KGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHV---NLPVALIT--VSDPDIGANGAVTCYIYN-PEVPFQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPTMFHMDPETGIISLTE-QLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLSILGTDNR-----QLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMP-PSNTTYKFVVPRTL-PGTIVTEVSAVDNDAEINAELRYHIVGGNPHN---LFHIDPVIGNITLMEPL 768 HSP 2 Score: 115.931 bits (289), Expect = 1.574e-26 Identity = 129/460 (28.04%), Postives = 203/460 (44.13%), Query Frame = 2
Query: 1097 VPVEITVEDINNYYPVIA--ILSTNERVEVRENTLPGNLITIK-VSDNDIGMNSKVNCEL-----QTESKIDFQLLKKK--ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL---------DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIV------------TIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT----RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSA 2356
+ V I VEDIN+ P A +L+ V V EN G I+ +D D N EL T S + + + E + L +S D E Q+ +++ D GSPP S + +++TD N+ SP F Q V + EN+ T V+QL+A+DRD A + Y L + GK F++D SG + T N +L+RE E+ V+ P V TIE + AP+ GVI + E + +T +D D G N V + Q K + + +ET ++LD ET Y +++ D G ++ + +VT+K+LD NDN P + P Y ++ +I K+ ++TV A D D +N + Y + P +F +D ++G I L ++LD ++ TI+A D
Sbjct: 137 IEVRINVEDINDNAPAFAAPVLT----VSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLV-TVNGLLNRE--ESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVI---YISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQ--LKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPT-----YKVSVPENNVIGKH--LITVSATDRDMDKNAEMVYFLGPDAPT----MFHMDPETGIISLTEQLDREKKANYSFTILAKDQG 573
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 200.675 bits (509), Expect = 2.892e-53 Identity = 205/774 (26.49%), Postives = 330/774 (42.64%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYA-------LPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQ--FLCFIQTKVLVNDRNDF-IDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQIS-----------------------LRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYK-VSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAP-NDLDLIQTFGINSNSG--EIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILST------NERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQ--------LIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA-----FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GV------IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV--SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELV--MTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVK 2305
V EE IG+++ + P S L + S + +G++++ R+D E LC C F+ +Q + + + L V L + D+ND+ P F +++ ES V + L A D D + N I+ Y++ +S L F + L L+ +LD E Y L L D + L I V D NDN P+F + V I E++ G+ VV + A D D+G G + Y+ L ++ +G +R +L ++ VVA+D + V V + + D N+ PV +++ + V++ EN G ++ I VSD D+G + V+ L+ + + K + + L + R D+E Q + S+ D G+P S ++++ + D+N+ +P F +YEVSLREN T VL L ATD D +I ++L E F ++ +G + T LDRE + A D A + VT+ DENDNAP F GV + +F V+E +G ++ +D D+G+N++V L R+ I + G + TL LDRE Y L V D G+ ++ S V++ V D NDN P +PN N + R + ++ ++V A D DAG+NGR Y I P +F L+ DSG + L +
Sbjct: 33 VDEEVLVGYVIGDLRQSNLLCVCFFPPAPHVSPLPLHTPSLCIVNELSGELSVALRLDREALCMEEPDACRSTGFMHTVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPD-AGTNSIQHYRISAASGD-GLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGG-QLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAELASPNKVQ--FLLKTTRLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQL-TLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVAL----NLVREAGPDWIGGAGDTPGGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTNDNAPVITSPN-TNDTWKHVRTFSPAGMLVGVSVTANDIDAGDNGRPLYEIIGGNPKG---IFLLNADSGALSLAR 792 HSP 2 Score: 112.079 bits (279), Expect = 2.561e-25 Identity = 145/581 (24.96%), Postives = 240/581 (41.31%), Query Frame = 2
Query: 788 VQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDL-IQTFGINSN-----------------SGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTE-SKIDFQLLKKKENLYSLASVRS---FDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYE--------VSLRENTATNTKVLQLNATDRD----GAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG---------VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMN-PNPINPEYN--ITRIINKNELVMTVQAFDTDAGENGRIKYR-IHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSATKPKM 2371
V+D ND+ P F VSI E+ G V A D D+G + Y I A + L + F + + LE R ++ + ++ ++ D NP+ V + I V D N+ PV T V + E++ G +++ ++ +D D G N + T+ + + Q + L +VR+ D E+ V + D G +S +V V + D N+ +P F+ + + V + EN + T V+ ++ +D D G +R G + + +KT + LD E + + A D + +I+++ D NDN P+F + E +++EN + ++ L ATDAD G N + F L LA + V ++FS++ + G + LDRE Y L V D G V V VLDENDN P ++ N N Y + + V TV D D G+N R+ + P+ + D G +R + LD + Q EL++ A DS +P +
Sbjct: 134 VRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRP-VRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEF-PTGAELASPNKVQFLLKTTRL-LDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTL-SELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIG--GAGDTPGGVVRTLVVLDREDRVQYELSVRAVDSG-RPAL 707
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 191.045 bits (484), Expect = 1.888e-49 Identity = 190/626 (30.35%), Postives = 288/626 (46.01%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS--SNKFELDTSKFPQISLRLKSELDYET--RKQYRLTLKACDRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDS----GDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNS-------------KVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPK--STDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAA--SIRYSLDEK-GKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMAT----STNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
V + + D+NDNTP+F T RE+ + A D D N+I L S S+ F + S + + L LDYE LT+ A D S + I++V DENDN PIF +N Y ++I EN G+ V+ VNA D D G L L+ Y+++ F IN+ SG+I L Y V A D N QK + V IT+ D+N+ P L V + ENT G ++ T+ +D D+ N ++N QL ++ N S AS+RS + D GSPP+ + +V V + D+N+ P F L Y + + E N+ + Q+ ATD D A ++ YS+ + F++D +G I T V LDRE + A D ++TT + + + D NDNAP F ++ E++ ++ L TDAD G N+++ F + Q+ Q FSV ++G + T+ SLDRET SY+L + D G P + +T + V VLD NDN+P ++ + E ++ + + +++ VQA D D G NGR+ YRI
Sbjct: 117 VRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGV-VTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLI-YSLEGSTQ------FRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLP--YAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSI----------VVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTL-VQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFI---TGGNQDGQ--FSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNG--PAGSRRTGTTTLDVLVLDVNDNRPLFLEG---SYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRI 711 HSP 2 Score: 161.77 bits (408), Expect = 2.199e-40 Identity = 160/638 (25.08%), Postives = 292/638 (45.77%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC-TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMN-SKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSP--PKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD--GAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAF------AHDAYVDP--FTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
S V++ + + NDN P+FS +++ E+ + S+ A D D ++ SY D S+KF LD + + + + LD+E ++ +T+ A D T + I++ D NDN P+F ++ Y + EN ++ + VV V A D+DS + Y+I + + ++ G + L R L + T + D +P V + V D N+ P+ + + + EN L G ++ + +D D +++ E F++ + + + S D E+ ++ D G K+ +V + + D+N+ P ++ L Y V++ ENT T + ++A D D ++ Y++D F++I+ SG I+T + LDRE + I F + D P TA+ + V ++D NDN P F +P V E + + + ++TATD D+G N V + + L R F + + G I TL LDRE +Y L + D+G ++++T +++ VLD NDN P + +P ++ + ++ +V+++ D D+G N + + I + + FS+ G +R V LD
Sbjct: 13 SARVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQV-SYHFSDDSDKFSLDPASG---LISVAAALDFEATPRFTVTVMARDGGGQETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFD--RNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGSTQFRINARSGD---ITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPP-NPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPD-----FQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTF---HPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQ---FSVGFRDGLVRTVVSLD 629 HSP 3 Score: 153.295 bits (386), Expect = 1.106e-37 Identity = 157/548 (28.65%), Postives = 249/548 (45.44%), Query Frame = 2
Query: 782 IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASV-RSFDFES--GQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-----GAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYV--DPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRE-----TFESY-TLEVGVRDKGKYPMATSTNVTVKVL--DENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSAT 2359
I + +ENDN+PIF+ Y VS+ EN G+ VV V A D D+G G V Y+ +D F ++ SG I + L +T V+A+D Q+ V I + D+N+ PV S +N+L ++ ++ +D D N+++ + S Y + ++ R+ D+E G S +I D GSPP ++ + +V + D N+ SP F + Y +++ EN VL +NATD D G S+ YSL+ G F+I+ SG I T +LDRE + + A D D T + +T+ D NDN P + +P T+ EN I ++A D D N L+ + +I + S + LQ LDRE +F S ++ V D+G P + + TV VL D NDN+P ++ + + + N + V A D D G NG + Y + P +P F LD +G I + +LD + + +L ++A+D T
Sbjct: 18 ITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQVSYHFSDDSD-----KFSLDPASGLISVAAALDFEATPRFTVTVMARD---GGGQETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLT-PVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLE--GSTQFRINARSGDI-TSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENG----TLVYAIDPPNPFYRINAASGKIRTTGLQ-LDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVG---LPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALP---RPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGT 542 HSP 4 Score: 142.895 bits (359), Expect = 1.673e-34 Identity = 165/615 (26.83%), Postives = 275/615 (44.72%), Query Frame = 2
Query: 260 DKLKFSSLKFNVDSQFLQINDNGD---VTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIES--YKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE-----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIR-----LERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP---VEITVEDINNYYPVIAILSTNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTE-SKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGK---AFFKIDHMSGWIKTKNVVLDREVIE--TIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF--GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEV 2014
+++ +S L + S + I +G VTL + +D E + + I ++ D ++T +++ D NDN+P+F +I + E++ ++ +A D D S E S Y LE S+ +F ++ S L LD E QY L ++A D D++ + I + D NDN P + Y V+I+ENT G+ + TV+A D D + G ++Y ID PN + IN+ SG+IR L+R +V +D +P + V + ++D+N+ P + + ++V E LP N L + +D D G N V + + DFQL + +L D E+ + TD G+P S+ ++ + + D+N+ +P F VSL E+ A ++ V+ LN TD D + S G F + G ++T V LDRE ++V A + T TT + V + D NDN P+F G E +V EN+ +I ++ ATD D+G N +V + + ++ Q+ + +VS LDRET + L+V
Sbjct: 164 NQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGT----------ISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGST-QFRINARSGDITSTTL---LDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPNPF-----YRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEP--SFVGLPYALQVLEG-LPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLV---QLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTV-VSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSY-EVSVPENVTRGAIILQVQATDIDEGINGRVWY---RIISGNQDGNFLVNVSSGLISRGATPLDRETVALHALQV 748 HSP 5 Score: 138.272 bits (347), Expect = 4.469e-33 Identity = 182/688 (26.45%), Postives = 288/688 (41.86%), Query Frame = 2
Query: 452 DSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLES----AFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDT-GSLVVTVNAYDKDSG--DLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQT------ESKIDFQLLKKKENLYSLASVR-------SFDFESGQVKSASIKCTDSGSPPKST--------DRSVLVHITDMNEYSPEFKQLIYE-VSLRENTATNTKVLQLNATDRD----GAASIRYSLDEKGKA----FFKIDHMSG--WIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP---EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETL--QSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEI---RLVKELDFDQIELTIIASDSATKP 2365
DS + + I D NDN+P+FS + + E+ P +++ + A D DF + L SS F +D + +S+ L LD E RL L +D L + V D NDN P F +LEN+ G+ V+ V A D+D G D G V Y+I + + TFGI+ ++G I + R Y VVA D P E+ V N ++ + + E +PG ++ ++V+ + K+ L E K Q ++ +N +A+++ + D E+ ++ D G P+ V V++TD N+ SPEF+ V +RE+ A T + L+ATDRD G S R + I + SG + + + I+F A D P + T + V + D NDN PIF + P +V E L+ + ATDAD G N QV F + K + +G I ++DRET +YTL V D+G P++ S V V V D ND +P ++ P ++ ++ V TV+A + G N + Y+I N+ F++ SG + RL+K +++ LT +A+D P
Sbjct: 1482 DSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRG-NVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGN----DTFGIDESTGLIVTVAPIDYETRPEYLLMVVATD---QAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVV-VRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQ--QESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGG--PREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIF-LSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIGP-----SDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAP---VQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNA----FTVHATSGLVTSTRLLKS--YERFNLTAVATDHGRPP 2141 HSP 6 Score: 131.339 bits (329), Expect = 5.310e-31 Identity = 171/645 (26.51%), Postives = 277/645 (42.95%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTIT-LRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSE----------LDY-ETRKQYRL-TLKACDRDS---CTDKELIIDVQDENDNKPIF-TKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLE--RRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFD-FESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEF--KQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAF------FKIDHMSGWIKTKNVVLDRE--VIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPE-------FTVKENMISTRLIGRLT-ATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTN-------------VTVKVLDENDNKPQWMNPNPINPEYNITRIINK--NELVMTVQAFDTDAGENGRIKYRI 2230
V + + D NDN+P F T+ +RES +++ A DRD + + + + + PQ L +++E D+ E Q+ L + A D S T L + V D NDN PIF + Y VS++E G+LV +V A D D+G G V + I++ I + G IR+ + R YT VVA D N P V + V+D+N+ P A L+ + V V E+ G+ + T+K ++N G N+K ++ K F + + S ++S++ F V TD G PP + V + D+N++ P F V++ E +++++ A D D ++RYS G F+I+ SG I T LDRE + +++ A V + +T + V ++D +DN P+F V+P+ F++ E+ +G ++ A DAD G N+ V + + A E K F++S+ G + L LDRE Y + V + A +T V V + D ND QW P N EY ++ ++ ++A D D G N + YRI
Sbjct: 1825 VYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIP------PQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGG----DKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRG-NPPLSGSAIVRVLVDDVNDERP--AFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLLKSYERFNLTAV------ATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARA-LDRESQAVYSLILLASDQGQPVS-YESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFI----AAGNEGNK-FNLSRWGLLVVLSDLDREVSPYYAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDIND---QW--PVFTNHEYTAGVAVDAKVGSELLQLEAVDRDVGNNSIVLYRI 2438 HSP 7 Score: 129.413 bits (324), Expect = 2.067e-30 Identity = 156/559 (27.91%), Postives = 246/559 (44.01%), Query Frame = 2
Query: 776 LIIDVQDENDNKPIFTKNFYKVSILENTDT-GSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAAN-QRKLYTFHVVAKDSDFNNPQK--EKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCE-LQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATD----RDGAASIRYSLDE--KGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTA---TTKIIVTIEDENDNAPIFG-VIPEFTVKEN----MISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETL--QSLDRETFESYTLEVG--VRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMT----VQAFDTDAG--ENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSA 2356
++I + DENDN P F Y+V + E T G V V A D D GD V+Y I + N TFGI++ +G + + L LY V A D + ++ V + V D+N+ P + S ++V E + T SD D G+N ++ + + + +F + +L V D E+ + +I D G+PP ++ +V V + D+++ P F L SL E A V ++ A+D R+ AA +++S G+ F D +G + N LDRE + D +P A + +IVTI DENDN+P+F V E + EN + T L G + A+DAD G N+ + + LL + + + G + Q LDRE LE+ V+D G+ VT VLD NDN P + N ++ + V T V+A D D G + G ++Y I + F +DE +G I V +D++ + L ++A+D A
Sbjct: 1158 VLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNT---AATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWF-LRSYEGPIDVSEGQPGPRIATFMASDQDSGLNGELEYSIIDGDPRNEFVISPADGDLRVRRYVE-LDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYV-NRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDR-----DRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVT--VLDVNDNTPTF------NVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSI----ASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQA 1693 HSP 8 Score: 127.487 bits (319), Expect = 8.466e-30 Identity = 172/769 (22.37%), Postives = 311/769 (40.44%), Query Frame = 2
Query: 251 ALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKF---PQISL-RLKSELDYETRKQYRLTLKA---CDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVN----AYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKL----YTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGM--NSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASI---------------RYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTAT------TKIIVTIEDENDNAPIF--GVIPEFTVKENMISTRLIGRLTATDADKGNNSQV--------------EFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ-----IELTIIASDSATKP 2365
L +L++S + + ++F+ +GD+ +++ ++L+ Q F ++ D +LTV +++ D++DN P+F + +L E+ V +S A D + E R + L+ S F F Q L + LD E +YRLTL D S K+ +I+ + DENDN P+F++ Y+ I EN+ G+++ +N A D D G + Y++ + F I+ + G + + ++ + ++ +D N V + +TV D+N+ P + S V + ++I +K D D+G+ V + + F + E+ + +V D+E+ + TD P + + V + + + F Y+ +L E T V+++ A + R+ E A I + G I T+ LDRE ++ + + D A + V + DENDN+P F G V+E+ L+ L ATD D G+N V +++L + + + I V+K F+E +T + + D G P +T+ N++V VLD NDN P +++P ++ + LV +V A D DAG NG++ +RI + + S+ G IR+ + D+ L ++A D P
Sbjct: 1312 GLNGELEYSIIDGDPRNEFVISPADGDLRVRRYVELDRETQ----------AFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDAN---EGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSS----AYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRN---ATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGI---DESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAEL-IAALQGEITTQ-AALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYIL---IIQNESGVTIVDVAKADFVE-------KTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPG--GYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDK----LSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPP 2039 HSP 9 Score: 112.849 bits (281), Expect = 2.429e-25 Identity = 139/550 (25.27%), Postives = 236/550 (42.91%), Query Frame = 2
Query: 674 QISLRLKSELDYETRKQYRLTLKACD---RDS---CTDKE---LIIDVQDENDNKPIF-TKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDA------PNDLDLIQTFGINSNSGEIRLERRLA---ANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYS--LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTV---KENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDE-NDNKPQWMN-PNPINP--EYNITRIINKNELVMTVQ-AFDTDAGENGRIKYRI 2230
Q + ++ LD E Y LT+ + D R++ T+K + ++V DENDN P F + V + E+ G+L+ ++A D+D+G G V P LI I + SG ++ A + F +VA D + P+ + + V D+N+ P+ + V V E PG L+ ++ +D D G N +V +++ D + + + +A + D E+ + + D G+PP S V V + D+N+ P F + VS+ E+ + + V + AT+ + +Y+ + GK F + SG + + ++ + E A A D P + V + D ND+ P+F + P TV E M I + A D D+G N V + L + F + + G I T ++LDRE+ Y+L + D+G+ ST VLD+ +DN+P ++ P+ P ++I V V A D D G N + Y I
Sbjct: 1782 QGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILI----IQNESGVTIVDVAKADFVEKTSQFILFRIVALDGG-SPPRSTTFNLSVIVLDVNDNVPIF-LSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGG-DKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLL---KSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFI 2321 HSP 10 Score: 89.3521 bits (220), Expect = 3.406e-18 Identity = 126/499 (25.25%), Postives = 220/499 (44.09%), Query Frame = 2
Query: 299 SQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSL-TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTS--KFPQISLRLKSE----LDYETRKQYRLTLKACDRDS-----CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDA----PNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINN----YYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQL-LKKKENLYSLASVRSFDFESGQVKSASIKCTDSG-SPPKSTDRSVL-VHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRY-----SLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAY 1708
+QF +GD+T +D E + Q I V D ND + TVN+ + D+NDN P + + +T+ E+ P + SA D D + EN Y ++ + + ++ + K L+L E + + + + + + DR S + + +QD NDN+P F Y + +LE S + V A D D G G V Y++ A P+ F +++ +G I +L Y +VA +D P + + V D+N+ ++P + +S E V R++ +I++ +D D G+N++++ + T D Q + ++ L + +V S D E+ S I+ D+G + + T + L V + D+N+ P F + YEVS+ EN +LQ+ ATD D + R S ++ G F ++ SG I LDR ET+ +A +A+
Sbjct: 287 TQFRINARSGDITSTTLLDREAVSQ---------YILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLN-ENGTLVYAIDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRS--IVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPD-------FQLDAATGLITTLVQLDREAVAAYQLRLVA--TDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESV-ARDSV----VISLNCTDADSGLNAELSFFI-TGGNQDGQFSVGFRDGL--VRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGN--FLVNVSSGLISRGATPLDR---ETVALHALQVEAF 751 HSP 11 Score: 85.1149 bits (209), Expect = 6.458e-17 Identity = 97/350 (27.71%), Postives = 155/350 (44.29%), Query Frame = 2
Query: 1361 QVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTAT-NTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETI-VFNAFAHDAYVDP---FTATTKIIVTIEDENDNAPIFGVIPE--FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKP-NSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPK 2368
+ SAS + + P SVL+ ITD N+ +P F YEV L E +T V + A+D D A + Y++ A F ID+ +G + T LD EV + + A D DP T+T + V + D ND P F E V E R I A+D D G N ++E+ ++ R + V I + + LDRET Y L + +D G P+ ++ V V+VLD +DN P ++N + +++ +V V+A D + G N + H+P + + F D +G + + + LD +++ LT+ D+ P
Sbjct: 1136 RAASASTRGICLTATPAQATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTAATFGIDNGTG-VLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPR-IATFMASDQDSGLNGELEYSIIDGDPRNEFV--ISPADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLN---LPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQ-HSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPS 1477 HSP 12 Score: 84.7297 bits (208), Expect = 9.771e-17 Identity = 149/619 (24.07%), Postives = 248/619 (40.06%), Query Frame = 2
Query: 335 TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLE--SAFDRDFSAENRIESYKL--EDSSNKFELDTSKFPQISLRLKSELDYETRKQ-YRLTLKACD------RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQ--RKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASV-RSFDFESGQVKSASIKCTDSGSPPKSTDRS---VLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLN----ATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTK-NVVLDREVIET--IVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKEN--MISTRLIGRLTATDADKG--NNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNK 2095
T+ +R+ + L + + + +C T + +V ++I D NDN P F + L E P +++ +A D D R+ Y + +++ F +D +++ LD+E Y L + A D R + + + V D ND P F +++ + G + T A D+DSG G + Y+I D D F I+ G++R+ R + ++ + Y ++AKD P + V + V D+++ PV L N + L + ++ SD + G N + S + + ++ L V R D E ++ D+ P + ++V I D N+ SP F Q+ YE + EN+ T + LN A+D D A++ YSL A+F ID G + LDRE I + D AT ++ VT+ D NDN P F V + V EN + T +I + A D D G + V + + F + + G I T+ +D ET Y L V D+ S + V + +E D K
Sbjct: 1123 TITQRLCTKVLVKRAASASTRGICLTATPAQA--------TTSVLIRITDENDNAPAFGAATYEVLLTEG-PSTAGVAVANVTASDPDEGDNARV-VYAIVSGNTAATFGIDNGTGVLTAVK---ALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPRIATFMASDQDSGLNGELEYSI---IDGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMG-TPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVL-AIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDG--GRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVI-VVKAMDRDLGVCDAGTVRYSI------ASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEK 1714 HSP 13 Score: 78.5666 bits (192), Expect = 6.573e-15 Identity = 97/397 (24.43%), Postives = 171/397 (43.07%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLED-SSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFT--KNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDL--IQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL----STNERVEVRENTLPGNLI--TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENL--YSLASVRS-FDFESGQVKSASIKCTD--SGSPPKSTD-----------RSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD 1555
S V + ++D+ND P F QT+++ ESL V ++ A + ++ N +YK+ N F + + S RL ++ +++ LT A D L ++V D ND++P+F N V+I E +V V A D D G G V Y+ + ++F IN+ SG I R L + +Y+ ++A D + P+++ ++DI++ PV +L + + + E++ PG + D D+G N+ V + ++ K NL + L V S D E + +K + + +P +T R V V++ D+N+ P F Y + + +++LQL A DRD
Sbjct: 2043 SAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATE-NYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRL-----LKSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNE------GNKFNLSRWGLLVVLSDLDREVSPYYAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVFTNHEYTAGVAVDAKVGSELLQLEAVDRD 2427 HSP 14 Score: 69.3218 bits (168), Expect = 4.207e-12 Identity = 64/230 (27.83%), Postives = 104/230 (45.22%), Query Frame = 2
Query: 413 QTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE-----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNN 1081
Q +++ DR + T++L + D+NDN P F ++L ES+ + + + D D S N S+ + + + F +R LD ET+ Y L ++A D + L + V D NDN+P+F + Y+VS+ EN G++++ V A D D G G V Y I + N F +N +SG I R R+ H + ++ FNN
Sbjct: 532 QLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDAD-SGLNAELSFFITGGNQDGQFSVG-FRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQ---DGNFLVNVSSGLI--SRGATPLDRETVALHALQVEA-FNN 753
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 188.348 bits (477), Expect = 1.174e-48 Identity = 191/664 (28.77%), Postives = 300/664 (45.18%), Query Frame = 2
Query: 404 CFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSN--KFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD------RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIR----LERRLAANQRKL--YTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPE---FTVKENM-ISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKY-PMATS----TNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
F Q +V+ N +V++ ++D+N++ P+F +++ E PVN A D+D S +N Y++ + + KF + FP L ++ ELD ETR++Y LT+ A D S T ++DV NDNKP+F + Y E + GSLV V A D D+G G V Y+ + P F ++S +G I +R Q ++F VVA D P +++ V++ V+D+N+ P A V + L L+ + SD D G+N + + ++ + +L + S D E + + TDSG+ P + +V V + D N+ P F + + V E+T ++ L A+D D S +RY++ A F ID +G + LD E N A D P ++ T ++V + D NDN P F +P ++ EN+ I TR+I +TA D D N ++ + ++AR+ F++ E G I T +DRE EV VR K P+ T NVTV V DENDN P+++ P I + R +V T+QA D D EN ++Y + +F LD +G I ELD
Sbjct: 725 AFYQLRVVANS-GGVAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKD-SGKNGEVKYEIGEGNGGEKFGI----FPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDV---NDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQ-----VNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLT-QLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITL--LGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLARR-LDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAF--LPGDVFASIMENIPIGTRVI-TVTARDPDADVNGELHY----SIARQFPPGAHFTIDPESGEICTAAEIDREVTGGL-FEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAI--LVDGLRAA-AGSVVGTLQASDPDEAENAAVRYAVTG---GDAAILFRLDRRTGIIETSTELD 1356 HSP 2 Score: 183.341 bits (464), Expect = 4.506e-47 Identity = 195/759 (25.69%), Postives = 325/759 (42.82%), Query Frame = 2
Query: 200 TVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVD----SQFLQI----NDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVR-SFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVI------ETIVFNAFAHDA-YVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKPKMVMLKLIIN 2395
T E P F+ ++ A D + ++++N D +Q+ ++ + G VT K +D E L + + Q DR + V + + DLNDN P+F ++ ++ E+ P +++ +A D D A + + +F+++ +S R+ LD E R Y+L + A D + + I V D D P F ++ Y + EN G+LV +V+A D V Y I + D +F I + G I + ++ Y VVA + V + V D+NN+ PV S + + + +++ +D D G N +V E+ + + + LY VR D E+ + S ++ D+G P S+ +V V + D+N+ P F Y E + V + ATD D + YS EK + F++D +G I + V DRE + + F+ A D P + V ++D NDN P F + + +V E+ + + R+TA+D D+G N + + + + E K + G I L SLDRE SYTL V D G P+A S V V+VLDENDN P++ TR+ EL++T+ A D D G +G ++Y I + F++D +G + L + LDF+ L + A D P+ L+++
Sbjct: 454 TAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQ------------DRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTG-AVSTRVS--LDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLN--ANVTYLIVSG---DQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGGVAG----EASVSVLVHDVNNHAPVFDRASYEVSI-AEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFPDGQLY----VRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSF-EKPQVNFELDSETGRIASLRV-FDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINE----GNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRV---GELLITLTASDEDTGPSGDVRYAI---VAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVH 1171 HSP 3 Score: 165.622 bits (418), Expect = 1.524e-41 Identity = 175/660 (26.52%), Postives = 287/660 (43.48%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYK-LEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENT-----DTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQ-TFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSG-SPPKSTDRSVLVH--ITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL----------DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP----EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW-MNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASD 2350
V + + D+NDN P+F+ E + + E+ + SA D D +N + +Y L S F +D + LR LD E R Y LT++A D TD L + V+D NDN P F+++ Y + E+ T +++ TV A D DSG G V Y + D D FG++ +G + + R L R Y A D + + V D N+ P ++ + + EV E+ PG +L+ I +D+D G+N+++ + S D + N L+ R+ D E + ++ +D PP +V V +TD+N+ +P F ++ E++ V + A D D + + Y+L G F ++ ++G ++ LDRE ++ A D P T+T + VT+ D NDNAP F P E + E+ + RL+A D D+G N ++ + +A G + + LDRE SY L V RD G + + +V V + D ND P + ++P ++ N L++ V A D D G +G++ Y + FS+ D G + L++ LD + Q L I A+D
Sbjct: 1502 VEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDAD-QGQNALVTYSVLSGSEGAFVVDAASG---VLRASRRLDREERASYLLTVRASDGTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATD---GGGLAATARLYVNVLDANDNAP--SVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSI---SSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALA-PEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVR-ELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRF---PRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRY----DIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENTQ---GPPVLILQVVARDDDLGSSGQVTYAAAG---GNDGGAFSVSPD-GHVHLLRSLDREAQPQHVLIITATD 2133 HSP 4 Score: 160.999 bits (406), Expect = 3.418e-40 Identity = 166/622 (26.69%), Postives = 271/622 (43.57%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLF---STIEQTITLRESLPVNYSMSLESAFDRDFSAEN-RIESYKLEDSSNKFEL----DTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAIL---STNERVEVRENTLPGNLIT-IKVSDND------------IGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSP-PKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGK-AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEF-TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTL-ARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
V + + D+NDN P F +E + +E V + L++A DRD +YK+ + + L +K + L LD E Y L ++A D S ++ + VQD NDN P F K Y+ S+ E++ G+ + + + G L + + +G + + L R+ YT + A D N P + I + D+N+ P I + V E+ PG + + V+D D +G N + + L ++LK L D E + + +I +D+G P +S S++V++ D+N+++P F Y +L E + V + A D D A +RYS+ +F +D +G + T V DREV ++V N A D P TA T + VT+ D ND P+F T EN + + ++A D+D G N V + + A+ +E+ ++ S++ G + TL+SLDRE E Y L V +D+G P+ ++ VTV V D NDN P + P+ +I V TV A D D G NG ++Y++
Sbjct: 9 VRVVVGDVNDNAPSFPEPGVME--VAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAALRDL--LHRGRGPLAVPF-----------------DPKTGMVSTRQPLDFEARRQYTLSLRAADGG-NPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQL---------DRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTGLVTTDGKV-DREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLT--GKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFY---PVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQL 593 HSP 5 Score: 160.229 bits (404), Expect = 6.225e-40 Identity = 172/651 (26.42%), Postives = 279/651 (42.86%), Query Frame = 2
Query: 476 INDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK--FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVREN-TLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVR-SFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRY---SLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---------ELTIIASDSATKPK 2368
+ND+ND+ P F+ L E P + +A D D S N Y + ++ F +D S + ++D E L + A D+ + L + + D ND P+FT+ Y + +EN+ G VV+V+A D D G+ G V YN D + F ++S +G++ + L + + Y V A+D + P V + V D+N+ +PV + EN + T+ +D D G N V +L FQ+ + S R S D E V + D G + V + + D + P F + Y + EN A T V ++A+ D A++ Y S D++G F I+ G I T N + DRE A+ V + V + D N++AP+F E ++ E+ + ATD D G N +V++ + + ++ F + +G + LDRET E Y+L V D G P+++S V V VLD NDNKP + + + + ++ LV VQA D DAG NG + Y P+ N F LD ++G I ++ D + + +++A+D +PK
Sbjct: 331 VNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDAD-SGLNAKLRYSIVSGNDLGWFSVDESTG---LVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRG-SPPLGSTAKVTVVVGDLNDNHPV--FYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQV----NAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANVTYLIVSGDQRGS--FSIEWSGGRIFTANAI-DREEQAFYQLRVVANSGGV---AGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEK-----FGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYV---FHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVN-----FELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGG-RPK 950 HSP 6 Score: 151.369 bits (381), Expect = 3.574e-37 Identity = 170/656 (25.91%), Postives = 293/656 (44.66%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTI-----EQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK--FELDTSKFPQIS-LRLKSELDYETRKQYRLTLKACDRDSCTDKE----LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYS-LASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAA--SIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKP 2365
T +Q+ D+NDN P + ++ ++ ES +L + D D N S + + + F L P + L++ S+LD E Y LT+ A D + L++ V D ND+ P F + Y ++ E GS V V A D DSG + Y+I + NDL F ++ ++G + + ++ ++ A+D P+ + +T+ D+N+ P+ T EN+LPG ++++ +D+D+G N V + ++ + + ++L + +++S D E + ++ D GSPP + V V + D+N+ P F + Y S+ EN T V + ATD D A ++RY L A F+++ ++G + T+ V LDRE A D + + +T+ D D P F F V EN+ L+G ++A+ D N+ V ++++ R FS+ G I T ++DRE Y L V G +A +V+V V D N++ P + + + E +I N +V+A D D+G+NG +KY I K +F G++ + ELD + E LT+ A D+ +P
Sbjct: 210 TAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGW---FSVDESTGLVTTDGKVDREVASSVVLNISAQDQG-AQPKTAYTSLTVTLLDVNDEPPLFT--QTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTR-VSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDL--NANVTYLIVSGDQRGS-----FSIEWSGGRIFTANAIDREEQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAPVF---DRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFP----DGQLYVRYELDRETREEYSLTVSAMDTGVEP 841 HSP 7 Score: 146.362 bits (368), Expect = 1.310e-35 Identity = 151/540 (27.96%), Postives = 245/540 (45.37%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRL---KSELDYETRKQYRLTLKACDRD---SCTDKELI-IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVI--AILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCEL-QTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEK--GKAFFKIDHMSGWIKTKNVVLDREVIETIV-FNAFAHDAYVDPFT---ATTKIIVTIEDENDNAPIFGVIPEFTVKENM--ISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFE-SYTL 2008
S+TVN+ + D+NDN PLF++ E V + A D D + + +Y E FELD+ SLR+ ++ + + ++ A D D+ + + VQD NDN P F K+ Y+ S+ E+ + ++ V A D D G G + Y I+ N+ F +++++G+I L L + YT V A DS +P V + V D N+ P ++LS + R L LIT+ SD D G + V + + F + + +++ LA R DFE+ ++ ++ D G PP+S+ ++VH+ D N+ P F S+ EN T+V+ + A D D + YS+ + A F ID SG I T +DREV + A D + T A + V + DENDNAP F V P + + + + ++G L A+D D+ N+ V + + + +F + + G IET LDRE+ ++TL
Sbjct: 845 SVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGV-TYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEG---GKFTVDASTGQITLLGSLDREETASYTLVVSATDSG-TSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGEL---LITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVF-LA--RRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTA-AEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRF-VTPTAILVDGLRAAAGSVVGTLQASDPDEAENAAVRYAVT-----GGDAAILFRLDRRTGIIETSTELDRESGHGAFTL 1366 HSP 8 Score: 106.301 bits (264), Expect = 2.559e-23 Identity = 181/773 (23.42%), Postives = 302/773 (39.07%), Query Frame = 2
Query: 236 GNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS---SNKFELDTSKFPQISLRLKSELDYE-TRKQYRLTLKACDRD------SCTDKELIIDVQDENDNKPIF-TKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI---DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSL-----ASVR-SFDFESGQV------KSASIKCTDSGS---PPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV------IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMN-------PNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKP-----KMVMLKLIINN 2398
G+++YA+ + N + F G V L +R+D ET Q L + R + + + + D NDN P F + ++ E++P+ + +A D D + Y + F +D + +E+D E T + +T++A D+ K + + V DENDN P F T V L GS+V T+ A D D + V Y + DA L + GI S E+ E A +T VVA ++ P+ ++ I + +P+ + E N L G TI + + + + ++ E + + + F LL + + A R SFD + + +S++ +GS PP S+ V + + D+N+ P F E+ + ENT + L+ATD D A + YS+ + F +D SG ++ LDRE + + A D ++ V + D NDN+P F + E + + +IG + A DAD G +V + L + G + + LDRE+ Y L D G +A + + V VLD NDN P N P P ++ RI A D D G N +++ I + P + F++ D G++ + + LD ++ L + SD A P V + LI+ +
Sbjct: 1110 GDVRYAI--------VAGNTHATFAIDRSTGSVFLARRLDFET----------QRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELH-YSIARQFPPGAHFTIDPESG---EICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAA-AGSVVGTLQASDPDEAENAAVRYAVTGGDAAILFRLDRRTGIIETSTELDRESGHGA-----FTLEVVAVEAKAAAPRTQRAENTIIANSMTFNHPLPRF---PQDYESPINLLQGQ--TIPMPSSYLFLRHHLDWEPEGQ-LVFFTLLLGVTRGHGVINPLDAPWRVSFDLTARCMFIVFSSLLSSLRDNGAGSFIRPPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASR-RLDREERASYLLTVRASDGT---HATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRI----------SATDDDEGVNAELEFSISSGDPEGR---FAVGND-GQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTD 1828 HSP 9 Score: 88.1965 bits (217), Expect = 7.753e-18 Identity = 92/353 (26.06%), Postives = 154/353 (43.63%), Query Frame = 2
Query: 263 KLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND-----FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE-----------DSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQK-EKVPVEITVEDINNYYPVIAILSTNERVEVRENTL--PGNLITIKVSDNDIGMNSKV 1255
+L+FS + + +F ND G +++ + +D E F V V+DR ++ V+L + D+NDN P F++ + +S PV ++ A D D S N Y L F L+T +RL ELD E R+ Y LT+ A D+ + L + V D NDN P F + Y+ +I E+ G+ V+ ++A+D D G G + Y+I + D F ++ G + + R L + Y V A+D P + + V +T+ D+N+ P + + V RENT P ++ + D+D+G + +V
Sbjct: 1763 ELEFSISSGDPEGRFAVGND-GQLSVARALDRERQS------------FYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDS-PVGAVVATVQAVDPD-SGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTG---EVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASG---DPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDG--GGPARSDTASVRVTLSDVNDCSPAFQL--SPYTVHARENTQGPPVLILQVVARDDDLGSSGQV 2090 HSP 10 Score: 77.411 bits (189), Expect = 1.469e-14 Identity = 103/449 (22.94%), Postives = 177/449 (39.42%), Query Frame = 2
Query: 1103 VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVS-DNDIGMNS------KVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI--FGVIP----EFTVKENMISTRLIGRLTATDADKGN-NSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATS--TNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSATKPKMVMLKLII 2392
V + V D+N+ P E V +E+ G + + + D D+G N K+ + + + + K+ L+ LA+ D E+ + +++ D GSP + V V + D N+ P F++ Y S+ E++ + L R G D +G + T+ LD E + A D P + ++ + D NDN P F +P +V E+ + +T TDAD N ++ ++ R V V ++ LDRE Y L + D GK P+A S ++ V V D ND+ P++ ++ V V A D D+G N +++Y I + + FS+DE +G + ++D + + L I A D +PK L +
Sbjct: 9 VRVVVGDVNDNAPSFPEPGVME-VAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLH-LATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAALRDLLHRGR-------------GPLAVPFDPKTGMVSTRQ-PLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGK-PVARSATASLVVYVNDVNDHAPRFAL---SAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVS---GNDLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTV 434 HSP 11 Score: 52.373 bits (124), Expect = 6.308e-7 Identity = 48/138 (34.78%), Postives = 62/138 (44.93%), Query Frame = 2
Query: 1721 TATTKIIVTIEDENDNAPIF---GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKI--FSVSKEGFIE--TLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP 2113
T T++ V + D NDNAP F GV+ E KE+ R + TA D D G N V K ++ +E + + V+K F+ T LDRE SY L V D G V V V D NDN P + P
Sbjct: 4 TYPTEVRVVVGDVNDNAPSFPEPGVM-EVAFKEDAAVGRQVLLDTAVDRDVGPNG-VNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKP 139
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: si:ch211-199f5.1 (protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]) HSP 1 Score: 170.244 bits (430), Expect = 1.324e-43 Identity = 181/680 (26.62%), Postives = 300/680 (44.12%), Query Frame = 2
Query: 188 TANLTVKEEFKPNQFIGNIKYALPDKLK-----FSSLKFNV----DSQFLQIND-NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFEL------DTSKFPQISLRLKSELDYETRKQYRLTLKACD-----RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNN-PQKEKVPVEITVEDINNYYPVIAI----LSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA------FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRL-----IGRLT----ATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFES-YTLEVGVRDKGKYPMATSTNVTVKVLDENDN 2092
T +TVK Q G + L D L+ S F + D + + + +G V+ ++ ID E C + C I+ VL + +++ D+ND+ P F+ E + + ES+ + + LE A D D N + +Y L D + +F L D +K+ + L +KS LD E +Y L L A D R T + I V D NDN P+F + V++ E+ G++++T+NA D D G G V+Y+ +P D ++ + F ++ +G++ L+ +L Y + A+D ++ P KV V VEDIN+ P I + S + V V E + + + VSD D N V C L+ F+LL +++ Y + + S D E ++ +D G+PP+ R V + D N+ P F + YE SL EN + V + A D D I Y++ E A + I+ SG I LD E + ++ F A D V P + V I DENDNAP+ P ++ RL +G L A D+D N ++ + +++ ++ + +I + E F D + ++L V VRD+G ++ + + ++V D
Sbjct: 26 TTAITVKYALYEEQPAGTLVGRLSDDLQGRVAEHPSRHFRLMRRDDFSLVHVEEADGTVSAREVIDREQQCGQAPSC------VIRFDVLCTLPRGLFQLVHAEVELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGG-NALRAYHL-DENERFGLALRARTDGAKYAE--LVVKSRLDREQEGEYTLQLTAWDGGDPPRSGTT--LVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDHELNSEYEISIQARDMGPSSIPAHCKVLVH--VEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLRGHPH--FKLLPYRDD-YVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALR-PLDYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVVTHPP---LRNGTGVVRLPRDAGLGYLVTVVRARDSDSEANGELSYRIVQ--GNERNLFRINRLGGEVFTNAASVTDAAASATRHSLVVMVRDRGSPALSATAAIEIRVGAHGDG 682 HSP 2 Score: 159.073 bits (401), Expect = 5.329e-40 Identity = 158/551 (28.68%), Postives = 247/551 (44.83%), Query Frame = 2
Query: 782 IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDL-IQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKV----NCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFK-QLIYE-----VSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKI-DHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRI---INKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVML 2380
+++ D ND+ P F ++ V I E+ G+ V A D D G L Y++D L ++ + E+ ++ RL Q YT + A D + P+ V ITV D N+ PV A S N V VRE+ PG L+T+ +D D G N +V + + E + FQL K L SL D E SI+ D G VLVH+ D+N+ +PE K I + V + E A + V + +D D A + + +G FK+ + ++ N LDRE + A D P A + V + DENDN P F E ++ EN + +TA DAD +N + + ++++ V S++ G I L+ LD E S T +V RD G P+ T+ V+V+++DENDN P +P P+ + R+ LV V+A D+D+ NG + YRI +++ +F ++ GE+ F A+ SAT+ +V++
Sbjct: 124 VELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHLDENERFGLALRARTDGAKYAELVVKSRLDREQEGEYTLQLTAWDGG-DPPRSGTTLVRITVLDSNDNSPVFAQTSCN--VTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKL-SLKG--QLDHELNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLRGHPHFKLLPYRDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVVTHP-PLRNGTGVVRLPRDAGLGYLVTVVRARDSDSEANGELSYRIVQ---GNERNLFRINRLGGEV-------FTNAASVTDAAASATRHSLVVM 657
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 235.728 bits (600), Expect = 2.000e-63 Identity = 234/749 (31.24%), Postives = 358/749 (47.80%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE--DSSNKFELDTSKFPQ---ISLRLKSELDYETRKQYRLTLKACDRD--SCTDKELI-IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQT---FGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAIL----STNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKK-ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGK-AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNE---LVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATK 2362
V+EE P ++G + A + S +F +S + G ++ RID ET Q S +Q + L N N I +V +Q++D+NDN P F T+ T+ +RES+ VN + + +A D D + N Y + D++ F L T+ P + + K LD ET Y+L + A DR + LI I + DEND+ P+FT+N Y SI ENT G ++ V+A D+DSG G + Y I D D IQ+ F ++S++G IR ++ L + YTF+V+A D P K + V I V D N+ P + I ++ EN+L N+ I V+D D NS+ EL+ + D K + Y + + D E + ++ TD G P +ST VL+ +TD+N+ SP F Y ++ E + VLQLNATD D ++ YS+ +F++D SG + T LDRE + ++ A D P T +T + VTI D NDN P F + T+ E + +++ATD D G+N ++ + + + A +V +F + ++ G + T LDRET Y+ V +D G + +S V + + D NDN P + P+ EY + I +NE ++ V A D D G N I Y I N FS+D +G I + LD + E L I A D K
Sbjct: 16 VQEEQPPGTYVGKVDGA--SAFEGSPKQFGFNS------NTGVISTTARIDRETTTQIS----------LQLRTL-NPSNQPI---SVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPD-AGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI----DWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGV--PSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQ--TELKITNGDDEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAK-PLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDA---QVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFY---PV--EYFAS--IMENEPPGKLLQVTATDADEGTNAVISYDIIGGNNNGN---FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNK 719 HSP 2 Score: 188.348 bits (477), Expect = 1.705e-48 Identity = 204/740 (27.57%), Postives = 340/740 (45.95%), Query Frame = 2
Query: 236 GNIKYALP-DKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTI-------EQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKEL---IIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVREN-TLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGK---AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKII-VTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL-DFDQIELT--IIASDSATKPKMVMLKLII 2392
G+IKYA+ D ++ +S+ F++DS G + K+ +D E +NS I + V +ND TV + + D NDN+P ++ I SL +N +++ D+D + ++ E K+ + ++ ++L+ LD E Y LTL D+ + L +IDV D NDN P FT N Y +I E GS V+ +NA D D GD G V Y+I NDL Q ++ SG + + L Q T + A+D + P+ V +T+ D N+ P + ++ + + E ++ ++ + +D D G N ++ E+ + L + L + D E+ + S ++ D G P + V + I+D+N+ +P F + Y S+ EN K+LQ+ ATD D + S D G F ID +G I T LD EV E A D + + A T ++ VT+ ++ DN P+F + FTV EN+ L+GR+ AT DK N + + ++ + +F V S G I+ +DRE Y L V R P++ V ++VLD NDN PQ+ + I +I ++V A D DAG+NG ++Y++ ++ + + ++ SG I+L ++L D D+ + T ++ASDS + P+ + + I
Sbjct: 239 GDIKYAIDWDAIQSNSI-FDLDSS------TGVIRTKQNLDFE--VKNSYT-----FNVIASDGGVPSKNDL---ATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSL-INTNIAYILVTDKDSNTNSQTE-LKITNGDDEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQ---VDFQSGLVTTAKPLDREQVSSVTITITAQDHG-SAPKTGSTTVTVTIIDGNDNKP--RFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTL-ASLDHEVEEFFSLIISAKDGG-NKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDK--NGSISYAIV-----SGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVI---VDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQL----TSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHI 936 HSP 3 Score: 174.866 bits (442), Expect = 3.017e-44 Identity = 176/667 (26.39%), Postives = 313/667 (46.93%), Query Frame = 2
Query: 419 KVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYT---FHVVAKDSDFNNP--QKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKG-KAFFKIDHMSG-WIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETF----ESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL-DFDQI-ELTIIASDSA 2356
+VL +D T+ + I ++ P F+ + S P++Y A D+D S +N Y + + + FP L ++ L + Y L ++A D + I +QD ND++ +F N ++ ++ EN+ G+LV T+ A+ D ++Y++ + F ++ SG+I RL + T +++ ++ +N+ +++K V +TV D+N+ PV + + V E +LPG+ + IK D D G N+K L + + +D + L+ ++ D E+ + +K TD+ + + + + + D N+ P F + Y V++ E+ + V+ LNA+D+D + I+YS+ A F ++ +G I K+ LD E + A D + P ++T + V + D NDNAP+F P TV+EN+ + +GR TA+D D G N+ + F + Q K FSV S I T+ ++D ET +S+ L V D+G ++T ++TV+V DENDN P +++P P +N VMT+ A D D NG++ Y I + F+L +G+++++ ++ D I +LTI ASD
Sbjct: 917 QVLASDSGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQD-SGKNGQLFYSIPQGNEEGLFGI--FPGGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSE-----SHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFS--RAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLS--KTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKS--LDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYS-----QTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSP----PAAAAGSSLN----VMTITAEDPDRNSNGKVTYSII----SGNNGYFNLHPSTGQLQMIHQIPDNPTIYQLTIQASDGG 1552 HSP 4 Score: 157.918 bits (398), Expect = 6.002e-39 Identity = 174/677 (25.70%), Postives = 282/677 (41.65%), Query Frame = 2
Query: 152 IFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNV---DSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRE-SLPVNYSMSLESAFDRDFSAENRIESYKLEDSS--NKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKV------------------NCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETF-ESYTLEVGVRDK-GKYPMATSTNVTVKVLDEN 2086
+F N FR V E P +G + D + + +++ +S F +G +T + R+D E L +N+ G + +Q + + ND D V + + DLNDN P+FS IT+ E SLP + ++ A D D +N Y L + +KF +++S L L LD ET Y L +KA D + + ++ I V D ND +P+F ++ Y V+I E+ GSLV+ +NA DKD G GL+ Y+I N L F + S +G + + + L +LY + A+D P V V + V D+N+ P+ + VREN G + SD D G N+ + CE+ T + ID + + + + L + TD GSP ST +S+ V +TD N+ SP F + + ++ N + DR+ + YS+ +F + +G ++ + + D I + A D T + V E P F + +V EN ++ + + A N +E+ L ++ F V K G ++T + +DRE S+ L V DK G +S VT+ V D N
Sbjct: 1049 LFVNNTFR-------FAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQITTRVRLDREELIKNT----GSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIK-AMDAD-EGDNAKFFYSLVSGTGMDKFFINSSTG---ELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGN---LAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGL-IPLSSTVNVTVNVLDVNDNAPLFPTQPVT--LTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLV----------------VMATDQGSPKLSTRKSITVQVTDENDNSPGF---VSPPAAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQIPDNPTIYQLTIQ--ASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGG-----FEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 5 Score: 152.14 bits (383), Expect = 3.565e-37 Identity = 199/775 (25.68%), Postives = 318/775 (41.03%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPDK---LKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE-LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQ-KEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRS---FDFESGQV-------KSASIKCTDSG------------SPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL-DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLT----ATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINP-EYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF-------DQIELTIIASDSATKPKMVMLKLI 2389
N TV E +G + DK + ++ + + + FL + G + + +D E Q +L + +V TVN+++ D NDN P FST + + + V + +A D D + +N + Y+L ++ S I L K ET QY + + A D S + I + ++ P FT + Y +L + V A D+DSG G + Y+I N+ L F G++ + + L + Y V A D P VPV I ++D N++ + ++ R V EN+ PG L+ V+ +D + K+ +YSL S S D SGQ+ + IK T S + K V+V +TD+N+ +P F + +Y +++ E + + V ++ A D D A YSL G F I+ +G + LDRE + A DA +T KI +T+ D ND P+F PE N+ LIG L A+D D G N L+K + +F V S G + +SLD ET + Y L + +D G P++++ NVTV VLD NDN P + P P + +N V A D D G N I + +++ P+ FS++ + EI + +D D +L ++A+D + PK+ K I
Sbjct: 747 NFTVYENVPKGTLVGRVYATTKDKNGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQ--------YLLAVIARV--GTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLD-AGKNGLVRYQLTSNAEGLLWINSTSGVIKLARKLTDGDET--QYTVQVLASDSGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIF----PGGKLYIRKSLLQALKGSYDLIVRATDGGV--PSFSASVPVTIYIQDSNDHRSLF--VNNTFRFAVAENSSPGTLVGTLVAH-----------------ALDHS--RTKDIVYSLISSESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKT-LDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVF---PESDYTVNITEDALIGSLVINLNASDKDIGQNG-----LIKYSISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLF----PTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSK---TFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGS-PKLSTRKSI 1464
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 212.616 bits (540), Expect = 4.138e-56 Identity = 222/798 (27.82%), Postives = 352/798 (44.11%), Query Frame = 2
Query: 59 KILEVLKNRPNHSYSLIKPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYS-LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW---MNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASD--SATKPKMVMLKLIINN 2398
+IL+V NRP +F A+ + V A +TV K N GN L++S N + F G VT+ + +D E Q S+ G + V DR D+ + + +ND+NDN P+FS ++E+ P +S A DRD S + ++ + + F +D S + + DYE + +Y LT++A DR ++ I ++D ND+ P+F+ + Y I E+T GS VVTV A D DSG G + Y + + N + F I++NSG IR+ L Y+ V A+D + V I ++DIN+ P I V E++ PG+ I + +D D N V L + D + L +L + D+E ++ D G+P +S+ V V + D+N+ P+F + +Y ++ EN A V + ATD D A+ I YS L F +D +G I T+ V LDRE I + A D + F A T + ++I DENDN P F F + E+ + +G+LTATD D G N V + ++ + + G + +LDRET SYTL V D G + + ++ V VLD NDN P++ + I + ++ + V+ V+ D D G NG I + ++ F++D +G + LD++ +LT+ A D S +K +K+ I N
Sbjct: 260 EILDVNDNRP---------------VFSSAQYTASVDEDVAIGAAMVTVTASDKDN---GNNA-----DLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFE---QRSSYALG---------LSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVS---ATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGI---ISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGN---VKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTR-VTIALQDINDNSP---IFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNT--DVFSINTSTGLITLKT--QLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTR-VPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIIS----GNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASV------HSTVLQVKVEDKDEGSNGAITLSLSGEGSDN----FTIDS-TGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIIN 989 HSP 2 Score: 210.305 bits (534), Expect = 2.365e-55 Identity = 205/726 (28.24%), Postives = 333/726 (45.87%), Query Frame = 2
Query: 236 GNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTV-NLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFP-QISLRLKSELDYETRKQYRLTLKACDRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE-KVPVEITVEDINNYYPVI--AILSTNERVEVREN-TLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF--GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINK--NELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKP 2365
G+++YAL D S+ + G +TLK ++D E Q ++ + K + SLTV + ++D+NDN P F+ T T+ E+L ++ +A D D A +I SY + + +F +I+ R+ LD ET Y LT+ A D + I + DENDN+P FT + +I E++ TG+ V + A D+D G G V Y I + N + +F ++ SG + + L ++ + ++ +V K SD +PQ+ + ++V D+N+ P ++ S E+RE+ ++ ++ +KV D D G N + L E +F + ++ + S D+E+ ++ D GSP KS V + I ++N+ P F S+ E+ A NT V++LNATD DG ++ + FKID SG I LDRE A + + + + D NDNAP+F G + ++ EN+ + + ++TATD D+G N++V + L K EV G + T + LDRE SY+L V D GK + +T+ + D NDN PQ+ +Y +T N ++ V A D DAG NGR+ Y I + + F +D +G I +V +D + + LTI A DS P
Sbjct: 615 GDVRYALSDNTDVFSINTST----------GLITLKTQLDYEKKTQ--------YMVTVTAK---DGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKI-SYSILSGNENMAFAMDRFTGEITTRVP--LDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP-SRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGN---SFQLDPRSGILSVRSTL--DRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSG----EIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTI----DSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTPLTFDIVEGNAGSSFKIDQSSGLISVAK-RLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAK-SLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNP-----ATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFS-----QSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIIS---GNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPP 1287 HSP 3 Score: 194.897 bits (494), Expect = 1.678e-50 Identity = 179/591 (30.29%), Postives = 288/591 (48.73%), Query Frame = 2
Query: 446 FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT--RIINKNELVMTVQAFDTD 2197
++ + V + + D NDN+P+F++ E + + E + + +++ +A DRD + ++ + ++ F ++ L +K E++ ET Y LT++A DR S +DKEL + V D NDN P+F Y S+ EN+ + V+TV A D D G ++ Y+I + ND + F INS SG I L ++ Y V A DS + K V I V ++N+ P A N VREN+ P + +KVS +D ++ + D + ++ + S A V D E + + ++ TD+G+PP S V + I D N+ SP+F Y S+ EN+A ++ +L ATD D + R + + F I SG I T LDRE T A D P ++ I VT+ D ND+ P+ +V+EN + R+ A+DAD G N+++ F LL E + +F++ + G I T LDRE YTL +GV DKG +++ +V + V+DE+DN P++ P EYN+T + + ++ V A D D
Sbjct: 1288 WVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNG---VLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDE---KRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYT----AKTNVTIRVINLNDITP--AFTQQNYTASVRENS-PTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRSGIISTADV--LDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRNDAFMIGASSGVI-TLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLS-----NEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQ-PT----EYNVTISESLPRGASIVQVTARDID 1852 HSP 4 Score: 191.045 bits (484), Expect = 3.071e-49 Identity = 204/740 (27.57%), Postives = 345/740 (46.62%), Query Frame = 2
Query: 266 LKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE-DSSNKFELDTSKFPQISL-RLKSELDYETRKQYRLTLKACDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASV-------RSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GA-ASIRYSL----DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT--VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKPKM----VMLKLI-INNH 2401
L F ++ N S F +G +++ KR+D ET N + Q + + N+ +++ D+NDN P+F+ +L E+LP+ +++ +A DRD EN +Y+L ++KFE++ P L K LD E + Y L + A D + + + + D NDN P F+++ Y +++ ENT GS ++ V A D D+G G V Y+I + N + F I+S +G I + + Y + AKDS P V ITV D N+ P+ A T+ ++ ++ + + +D D G N++V + +++ + +++ ++ + + E+ + +I+ +D GSP ++D+ + V + D+N+ P F Y S+REN+A +T VL + A D D GA A +RYS+ DEK FKI+ SG I T LD E A D+ +TA T + + + + ND P F +T V+EN ++ + +++A+D D + L ++ ++ K + G I T LDRE Y ++V V D G P++ T VT+K+LDENDN P++ + + +I + + A D D G N RI Y + S+ F + SG I L + LD + +L I A D T P+ + + +I IN+H
Sbjct: 1029 LTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTA-NYTLVVRATETGSQGESVYNN---------ATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRD-EGENAKVTYELSVGDTSKFEVN----PATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGN---AFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVP-PWVSTAFVAITVADENDNSPIFASNETSYGID-EGVSIGSRVAVVTATDRDEGSNAQVF----------YSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEK---RFKINSTSGVIMT-TTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAF-TQQNYTASVRENSPTSTSVVKVSASDRDSFGS------LSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKF---DSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNL------SRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDH 1715 HSP 5 Score: 187.963 bits (476), Expect = 2.610e-48 Identity = 185/658 (28.12%), Postives = 315/658 (47.87%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIE-SYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS--CTD-KELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQK-EKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTES-KIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPKMVMLKLIIN 2395
TV ++I D+NDN P+FS+ + T ++ E + + +M +A D+D + S+ ++++ F LD + + LD+E R Y L L DR S TD L+I+V D NDN P+F+ + Y+ + ENT G+ V+A D+DS G +++ I ND + F I+ ++G I + + + Y V A+D P K + V I +ED+N++ PV + +N ++ E+T+ G+ ++T+ +D D G ++ L + + K F + N S+ D E+ S ++ D GS +S+ V + + D+N+ SP F Q Y + E+++ ++ Q+ ATD D +++ +RY+L + F I+ +G I K LD E + A D ++ T + V ++D NDN P F + TV EN+ + + +TATDAD G N ++ + +L F+ G I T LDRET SY+L + D +T V + + DENDN+P + P+ +NI+ V + A D D G NG + Y I + + F LD SG + + LD + I L + ASD+ + + + + ++
Sbjct: 256 TVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTG---VVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGIIKGNDDGV---FTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGV--PVKYDTAQVTIFIEDVNDHSPVFS--PSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNI---DANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIF-QGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTD-VFSINTSTGLITLK-TQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFT----GEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPS----RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNS---FQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVS 883 HSP 6 Score: 187.578 bits (475), Expect = 3.503e-48 Identity = 187/662 (28.25%), Postives = 309/662 (46.68%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE-KVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA---ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG------VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSAT--KPKMVMLKLIINN 2398
V + + D NDN P F +RE+ P +++ +A DRD S N +Y L NKF ++ SK +I R + LD+ET+ Y + + A D T LI V D NDN P F + YK + E+ GS+V + A D D G + Y++ + + F ++S G IR + A ++ ++ V + D +P + + VEI + D+N+ PV + S V E+ G ++T+ SD D G N+ + + + L + +++ RS DFE + + TD GSPP + +L+++ D+N+ P F Y+ ++ENT T Q++ATDRD + A + + F ID +G I D E A D V T ++ + IED ND++P+F IPE TV + + T +TATD D G ++E+ L+ V+ F++ + G I LDRET SY+L+V RD G ++ST VT+ + D NDN P + P + ++ + + V A D D NG ++Y + + VFS++ +G I L +LD++ Q +T+ A D T + + ++K+++++
Sbjct: 56 VVIDVKDENDNAPEFPLNSYVFNIRENTPA-AQVAIVTATDRD-SGTNAAITYSLFSGENKFMMN-SKTGEI--RTVTPLDHETKDSYTMRISAFDGKHTTFVPLIT-VDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGD----TSYFTVDSQ-GVIRT--KGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFS--SAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVS--RSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAK-SPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVT-----VTATDLDSGPRGRLEYRLI-----SGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPY----VFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSD-----NTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDD 677 HSP 7 Score: 184.496 bits (467), Expect = 2.892e-47 Identity = 180/641 (28.08%), Postives = 288/641 (44.93%), Query Frame = 2
Query: 470 LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIIN--KNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSA 2356
+ ++D+NDN P F+ + E + V + +A D D R+ + ++ F +D+ Q +R K D ET+ Y++ L+A D S + I++ D NDN+P+F+ Y S+ E+ G+ +VTV A DKD+G+ + Y+ + N F +++ +G + + R L QR Y + D + P + + I V DIN+ PV + + R V+ENT G ++ +D D N + + + + + S+A +S D+E+ +++ D G P K V + I D+N++SP F Y + E+T + V+ + ATD D + Y L K F ID SG I+ + LDRE + A D +++T++ + ++D NDN+PIF F V E+ IG++ ATDAD +N V + L + +FS+ + G I LD E Y + V +D G ++ T V V V D NDN PQ+ Y T N V V A D D+G NG+I Y I + N F++D +GEI LD + I LTI A D +
Sbjct: 156 ITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDS----QGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGN---TNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRG-SPPLTDTSHLLINVNDINDNPPVFSPSAYQSR--VKENTPAGTQVS--ATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIA--KSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSS-ELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYAL-------SDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFA-----KSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENM---AFAMDRFTGEITTRVPLDRETIASYSLTINADDGS 766 HSP 8 Score: 113.62 bits (283), Expect = 2.327e-25 Identity = 101/361 (27.98%), Postives = 171/361 (47.37%), Query Frame = 2
Query: 1337 RSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEY--NITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKPKMVMLKLIIN 2395
R FD ES ++ D+ + V++ + D N+ +PEF Y ++RENT +V + ATDRD A+I YSL G+ F ++ +G I+T LD E ++ A D F ++T++D NDNAP F + + + V E++ ++ +LTA D D G N+++ + L+ F+V +G I T + DRET SY + + +D G + V +++LD NDN+P + + +Y ++ + ++TV A D D G N ++Y + N F+LD +G + + + LDF+Q L + +D + P L+IN
Sbjct: 26 RKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPA-AQVAIVTATDRDSGTNAAITYSL-FSGENKFMMNSKTGEIRTV-TPLDHETKDSYTMRISAFDGKHTTFVP----LITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDT------SYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFS-----SAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNH---AFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLIN 365 HSP 9 Score: 73.559 bits (179), Expect = 3.697e-13 Identity = 65/218 (29.82%), Postives = 96/218 (44.04%), Query Frame = 2
Query: 1580 LDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPE-FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRI 2230
+D + F ID +G I T DRE A DA T +++ ++DENDNAP F + F ++EN + + + +TATD D G N+ + + L K SK G I T+ LD ET +SYT+ + D GK+ T+ + V D NDN P + Y + +V + A D D G N R+ Y +
Sbjct: 4 MDGNDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQ-VAIVTATDRDSGTNAAITYSLFS------GENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFD-GKH---TTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAV---GSIVRQLTAVDLDVGINARLSYSL 207
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 203.371 bits (516), Expect = 5.196e-53 Identity = 208/749 (27.77%), Postives = 348/749 (46.46%), Query Frame = 2
Query: 209 EEFKPNQFIGNIKYALPDKLKFSSLKF-----NVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDA-PNDLDLIQTFGINSNSGEIRLERRL-AANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLP-GNLITIKVSDNDIGMNSKVNCELQTESKIDFQL--LKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDAD-KGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGK-YPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSATKPKMVMLKLI 2389
E + Q I +K D KF+ +F N D F ++ +G +TL K +D ET Q + K + D ++ VN+ + D+ND P+FS E T++E + A RD + + +++ L S +L L+SE+D+E LT++A D+ + + I V D NDN P F + V + E+T G TV+ +D DSG LG V +++ + P L F ++SN+G + L + + N + YT V A+D + P+ +E+ V D+N+Y PV S V E T P N+I + +D D G N +++ +SK+D L+ ++ + + D E +K +I D G+P +S+ V V + D+N+ +P F+Q Y ++EN T + ++A+D D ++ + Y D + A F +D +G I T VLDRE + VF+ A D P T++ V + D ND +P F TV E++ + L ATD D +G NS + ++++ K FS+++ G + + LDRE + L V DKG + T T + + VLD NDN P ++N + + +V V A D+D G+NG+++Y+I N + F ++E +G I ++ LDF+ + L + A+D K + +L+
Sbjct: 610 ENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVF-SVDGSGLITLAKLLDRET----------QDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTG---TLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTL-----FNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGG-SPPRSSTAMLELKVVDVNDYSPVFGNWSYT--AHVLETTPPDSNIIEVVATDVDSGENGRISYAF--DSKVDTSKFGLRNGGKIFIKSKLDREDIEEYNLKVIAI---DHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQ-VAQFIVDKQTGKITTSQ-VLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAG-------PKAFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFK---TVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDG---TFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLV 1316 HSP 2 Score: 187.963 bits (476), Expect = 3.198e-48 Identity = 203/675 (30.07%), Postives = 306/675 (45.33%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLF--------STIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS--SNKFEL------DTSKFPQISLRLKS-ELDYETRKQYRLTLKACDRDSCTDK---ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILST-NERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTES---KIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GAAS-IRYSLDEKGKA-----FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKV--LDENDNKPQWMNPNPINPEY-NITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIASDSATK 2362
S TV + + DLNDN+P F E R+ L A D DF + N +SY + N F+L D + + + S +D E Y L + A D + + L I V+D NDNKP F+ Y +I EN D G+ ++ V+A DKD G + Y+I+ +D I FGI+ +G I RL ++ Y V A+D ++ V I V D+N+ PVI + T +V EN G + + VSD D G N +VN L+ + F +L + +A +S D E+ C D G PP++T++S +++ D+N+ +P+F + YE + EN NT V +NA D+D G+ S + Y++ ++ +F ID SG I T LDRE I +V HD P + +IV + D NDN P F ++ EN S + +L A D D G NS + + +L F ++G + ++LD E SYT +V D G S N TV V D NDN+P + +P+ + EY TRI + + ++A D D+ + ++ I + VFS+D SG I L K LD D LT+ A D +
Sbjct: 41 SYTVLVYVQDLNDNSPSFVRGTSAKLVVFENDKDFRQKL---------IAVDSDFGS-NSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAI--FGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDES---IIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTA-TDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILT------PNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGG----GRSCNATVHVSLTDLNDNQPVF-DPSSYSVEYFENTRI---GQSICQLKAIDRDSPKFAITRFIIEQ---GNADEVFSVD-GSGLITLAKLLDRETQDNYLLTVKAVDGGGQ 681 HSP 3 Score: 181.8 bits (460), Expect = 3.048e-46 Identity = 193/666 (28.98%), Postives = 310/666 (46.55%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE--DSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD---RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDF-ESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEK--GKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKN-----ELVMTVQAFDTDAGENGRIKYRI-HNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKPKMVMLKLI 2389
TV++ + DLNDN P+F ++ E+ + S+ A DRD S + I + +E ++ F +D S + L LD ET+ Y LT+KA D +DS + I V D ND PIF+K Y +I E++ S++ V+A +D G V+Y+I N +++ INS +G + L+ + + K+ + ++ + D P V I V DIN+ P S++ V + E+T G+ T+ V D D G+ +V+ L + F L N +L+ + D+ S + + ++ D GSPP+S+ + + + D+N+YSP F Y + E T ++ ++++ ATD D I Y+ D K F + +IK+K LDRE IE A D +++ + V ++D NDN P F F VKEN +G ++A+D+D+G+N V + +A+ F V K+ G I T Q LDRE SY + D G P T VTV V D ND P++ +Y++T +N++ L+ + D G N I Y I PK FSL++ +G + LV LD + L ++ASD + + I
Sbjct: 584 TVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRD-SPKFAITRFIIEQGNADEVFSVDGSGL----ITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVL---INS-TGTLYLQSEV--DHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSP--QFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNL---DSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGLRNGGKIFIKSK---LDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQ-------FIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFS-----KNKYSVT--VNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPK------AFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYI 1210 HSP 4 Score: 171.785 bits (434), Expect = 2.994e-43 Identity = 192/690 (27.83%), Postives = 311/690 (45.07%), Query Frame = 2
Query: 422 VLVNDR--NDFIDSLT-VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKL--EDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD---RDSCTDKELI-IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQK--EKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA-FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVK--ENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSG--------EIRLVKELDFDQIELTIIASDSATKPKMVMLKLII-----NNH 2401
V+ +D+ N ++++T + + + D+NDN P+F T+ E LP+ ++ A D D ++ YK+ ++ F+++ + +LR LD+E +Y L + A D + T +L+ I V+D NDN+P F KN I EN + V T+ A+D DSG + Y ID+ + F INS +G I+ + + Y+ V A D F + ++I ++D+N+ P +S N + + + +I D D G V + + F L K L + S D+E + I TD GSPP ++ + V + D+N+ PEF + ++ ++ EN T T V+++ A DRD A + YS+ + F ID SG I T N +LDRE +T A ++T + + + D NDN P F + P T+K EN RLI LT D D GNN++V + ++ F++ + G + T LDRET SY L V +D N+T+ + D+NDN P + I+ + ++ + A D D+G NG I Y + N V+S+D +G E + +E +F IA D PKM ++ + I NNH
Sbjct: 1193 VVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVR-YKIVNGNTDGTFKINETTGVISTLR---ALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPR---AHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAP--KFVSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTG---VLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVT-NSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKF-ISPVVTLKVPENS-PARLIYTLTVQDLDYGNNTKVLYSIM-----SGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQS---LYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLS----NDTYGVYSIDSRTGIVYSAARFETSIKQEYNF-----FCIAKDQGQDPKMAIVPVRIKIEDKNNH 1850 HSP 5 Score: 166.777 bits (421), Expect = 1.239e-41 Identity = 183/673 (27.19%), Postives = 296/673 (43.98%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLFS---TIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQIS----LRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI-DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAA-SIRYSLDEKGKA--FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNEL---VMTVQAFDTDAGENGRIKYR-IHNPKPNSKQPVFSLDEDSGEIRLVKELDFD----QIELTIIASDSATKPK----MVMLKLI 2389
S V +++ D+NDN P+ T+ + + E+ + ++ S D D S +N + LE F + KF ++ + + LD ET + L D+ T+K I+V D ND P F ++ Y+ + EN +LV VNA D+D G ++Y I + + F I+ +SG I L Q V+ D + P + V + + D N+ P S N + EN+ G+ ++ + D DIG NS + + T + F L ++ L + + R+ D E + + TD G +S + +V V +TD+N+ P F Y V ENT + QL A DRD +I + E+G A F +D SG I T +LDRE + + A D + +T+ D ND PIF FT++E+ + +IG + A DKG N++V + + K I ++ G + +D E S L V +DKG P+ NVT+ V+D NDN PQ+ N + R+ + TV FD D+G GR+ + + NP +F+LD ++G + L K +D+ L + A D + P+ M+ LK++
Sbjct: 262 SAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDAD-SGKNGEVNVTLEGGDGYFSM---KFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRG-SPPLSDNCSVIVNLTDSNDNDPYFNQSSYN--ASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTPFF--LDPRKGL--VTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDG-SGLI-TLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSI-----SKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQF------NSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPG-----TLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVV 903 HSP 6 Score: 159.458 bits (402), Expect = 1.933e-39 Identity = 189/659 (28.68%), Postives = 289/659 (43.85%), Query Frame = 2
Query: 458 LTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKS-ELDYETRKQYRLTLKACDRDS----CTDKELIIDVQDENDNKPIFTKNF-----YKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCELQ--TESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GAAS-IRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRL---IGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNEL--VMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKP 2365
L +++ + D NDN P FS + + T+ E++ V S+ SA D+D I+ Y +E S+ + P + + + LDYE ++ Y + +KA D+ S + + I+V D NDN P+ ++ Y+V+ EN G+ V V+ D DSG G V ++ D F + ++ I + + L + V D + P+ + I V D+N+ P + R V EN L+ I D D G NS++ + TES+ + + + D E ++ D GSPP S + SV+V++TD N+ P F Q Y SL EN+ + + V+QL A D D G S I YS+ FF +D G + T + LD EV + F A D AT + V++ D NDN P+F P E +TR+ I +L A D D +F + + + + ++FSV G I + LDRET ++Y L V D G V + VLD ND P + EYN T + L + V A D G N + Y I K N+ V L +G + L E+D ++I LT+ A D T P
Sbjct: 156 LRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQ-YSIETHSDPQAI-FGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVT--ENATIGTQVARVSVSDADSGKNGEVNVTLEG-GDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKG-DPPRTTEKSFRINVGDVNDCAPKFDRHTYETR--VWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTPFF-LDPRKGLV-TNSRTLDHEVQSSYTFQVAATDGGGRSCNAT--VHVSLTDLNDNQPVFD--PSSYSVEYFENTRIGQSICQLKAIDRDSP-----KFAITRFIIEQGNADEVFSVDGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFS-----KAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSIS--KGNTDNIV--LINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPP 786 HSP 7 Score: 154.066 bits (388), Expect = 9.353e-38 Identity = 171/670 (25.52%), Postives = 287/670 (42.84%), Query Frame = 2
Query: 422 VLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSE-LDYETRKQYRLTLKACDRD--SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLP--GNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRL----IGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMT----VQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSATKPKM 2371
VLV+DR D+ +V + + D NDN P F+ +L E+ P + A D D EN + Y + + F LD P+ L S LD+E + Y + A D SC + + + + D NDN+P+F + Y V ENT G + + A D+DS + + I+ N ++ G SG I L + L + Y V A D + + + V ITV D+N+ P+ + N ++ L G++ I D G N++V + + + L+ LY + V D E +++ D G+PP +V + + D+N+ SP+F V L E+T ++ D D + +SL F +D +G + ++ + A D P ++T + + + D ND +P+FG ++ +++ T I + ATD D G N ++ + K + K F + G I LDRE E Y L+V D G ++S +V V V D NDN P + + + + +NE V T V A D+D G NG + YR +++ F +D+ +G+I + LD + +I+A+D + P++
Sbjct: 468 VLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDI-GENSLILYSILTPNTPFFLD----PRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSC-NATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDG----SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAI-VNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAIS---RDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEV---DHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFG---NWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYA----FDSKVDTSK-FGLRNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQ-------QASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRF-----DTQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRV 1100 HSP 8 Score: 152.91 bits (385), Expect = 2.017e-37 Identity = 177/693 (25.54%), Postives = 303/693 (43.72%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQ-ISLRLKSELDYETRKQYRLTLKACDRDSCT-DKELIIDVQ--DENDNKPIFTKNFYKVSILENTDTGSL----VVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK-VPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLK----------KKENLYSLASVRS------FDFESGQVKS--------------ASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASI-RYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG---VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD-----QIELTIIASDSATKPKMVMLKLIIN 2395
V + I ++ D+ P F + QT R S+P N + R ++ + +Y + + F IS+ LDYE+ K +RL L A + + + +I+D+ D NDN P F + + E DTG+ VV V A D DSG G V Y+I N+ + F I+S +GEI + L ++ +F +V + +D P K V++ V D+N+ P+ LS V +RE+T G ++T V+ D S++ L++ S +L+ + YS S D ++G + + ++ D G PP+ LV++ + P+F+ Y + EN T VL + TD + R S + + +F+I SG I N LD E + A D + + + D ND P+FG + +++ E + ++ ++A D D G N +V F + + + + F++ K G I T ++LD ET +++ + V D+G PM T +VT++VLD NDN P + P P + + + N + + A D D+G N R+ + + + Q +F +D+ SG + D++ Q LTI A+D+ P + +I+N
Sbjct: 1948 VQIVIGNIQDDPPRF--LNQT-PARVSIPENSKVGSYITTVRARASSDAQVTYSIISGNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAE--DTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV---FTIDSTTGEITTAKLL--DRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLS---EVNIREDTRTGAVVTSVVA-TDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQR----ALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNYFRIGQRSGVISV-NKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWS--EGIPVGTIVVNVSAADKDSGANGRVWFAI-----QSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGP--NDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIG---GTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVN 2609 HSP 9 Score: 142.51 bits (358), Expect = 3.560e-34 Identity = 198/740 (26.76%), Postives = 316/740 (42.70%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQI---NDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQIS--LRLKSELDYETRKQYRLTLKACDRDSCTDKELI----IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVI----AILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDR-----SVLVHITDMNEYSPEF--KQLIYEVSLRENTATNTKVLQLNATDRDG--AASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEF-------TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEV---GVRDKGKYPM-ATSTNVTVKVLDENDNKPQWMNPNPI--NPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
VKE ++G + + D+ + + D+Q Q G +T + +D E + T + R +D V + + D+ND +P FS + ++T+ E LPV S+ A D D N +Y + F L+ Q++ L L S LD E ++ L + A D+ E I I+V D NDN P+F ++ E GS+V V A D D GD G V Y I N TF IN +G I R L Y V A D + V I VED N+ P I E V + NT N+ TIK D+D G+NS++ + ++S + + L + + D E S ++ TD + DR ++ + I D+N+ +P+F + L Y + E+ N +V + A D D ++ Y + F +D +G +K LD E + + A D P T+ ++ + + ++ P PEF TV EN + + ++TA D D G+N+++ + ++ E+ K FS+ K G I T LDRE ++Y L V GV YP +ST+V + V+D NDN P++++P PE + R+I +TVQ D D G N ++ Y I + + F++ +GE+ +LD
Sbjct: 1025 VKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQFIVDKQTGKITTSQVLDREAKAS-------YVFSIVATDGGSSPR---VDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSLN-----QVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGN---TDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPI--NT---NVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGL--IQTTHPIDREEISEYSLKVRATDQAFTEQ--DRLYNTATLKIIIQDLNDNAPKFVSRNLTY---VMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIG-SLDYEDVPQYTLHISATDLGSPPLTS-YQLFNVVVVDVNDNP-----PEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTY----SIPSGVEMDK-FSIDKHSGLIVTNSILDREKKDTYFLTVHATGV----SYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARLI----YTLTVQ--DLDYGNNTKVLYSIMSGNTDG---AFTIGRSTGELSTTTKLD 1709 HSP 10 Score: 133.265 bits (334), Expect = 2.428e-31 Identity = 102/317 (32.18%), Postives = 166/317 (52.37%), Query Frame = 2
Query: 683 LRLKSELDYETRKQYRLTLKACDRDSCTDKEL----IIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNP-QKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN--LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVK--SASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFF 1606
+ + LDYET++++ L + A D D+ K + I+V D ND KP+F ++ Y E G++VV V+A DKDSG G V + I + +D +F I+ +G IR +R L + + T HV + +D +P V V I V D+N+ PV + N+ V+V EN LP N L I +D D G N++++ + + L+ K L + +FD+E+ V S +IK TD+G+PP S++ +++V++ D +EY P F ++ Y+ + N V Q+ ATDRD ++G+ FF
Sbjct: 2359 ISVNKPLDYETKRRFLLVVSAID-DTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDK---GSFAIDRKTGVIRTQRAL--DHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPND-VQVLEN-LPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGW--LTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSG--------DQGRVFF 2657 HSP 11 Score: 131.339 bits (329), Expect = 9.066e-31 Identity = 154/651 (23.66%), Postives = 290/651 (44.55%), Query Frame = 2
Query: 458 LTVNLQINDLNDNTPLFSTIEQTITLRE---SLPVNYSMSLESAFDRDFSAENRIE-SYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTV----------------------------NAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYT-FHVVAKDSDFNNPQKEKVPVEITVE-----DINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMN-SKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRY-----SLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP--EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRE--TFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNS 2251
+ +++ + D NDN+P F L E + + + + +A D D ++ S + + F +D++ + +L LD ET + L ++ D T+ ++ + V D NDN P+F +V+I E+T TG++V +V +A D+DSG + Y+ N D I + I++++G I R + R + V A D PQ+ V V I + ++ +Y+ +V EN + G +++T++V+DN G+ +++ ++ ++ + ++ + S+ + D+E+ + + D +P K V ++++D+N+ P F Q Y E T V+ ++A D+D A+ R S D+KG F ID +G I+T+ LD E I+T + A D P + + + D NDN P+F V + V EN+ + + ATD D G N+++ F ++ Q +F + K G++ T + D E Y+L + D G P++++ + V V DE++ P + N ++ ++++ + V V A D D+G+ GR+ + +NP N+
Sbjct: 2051 MILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKV-TATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKL---LDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDP-LSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNS-DQID-YKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVP-PQRALVYVRIIITREPKFELPSYFG-----------KVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENS---NYFRIGQRSGVISVN--KPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGS--FAIDRKTGVIRTQRA-LDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTG-----QGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSF---NRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFFVFYNPTSNA 2666 HSP 12 Score: 122.094 bits (305), Expect = 5.957e-28 Identity = 162/646 (25.08%), Postives = 276/646 (42.72%), Query Frame = 2
Query: 530 TLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS--SNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD-----RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKD------SDFNNPQKEKVPVEITVEDINNYYPVI--AILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCT--DSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS----IRYSLDEK--GKAFFKIDHMSGWIKT----KNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF--GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSATKPK 2368
T+ E+ P S+ +A+DRD S N +Y + +KF +D ++ S LD E + Y LT+ A R S T + I+V D NDN P F + + EN+ L+ T+ D D G+ V+Y+I + N F I ++GE+ +L + Y V AKD + F N + I +ED N+ PV ++ S+ + E T PG +++ + SD D G N + L ++ + + + +YS A FE+ + + C D G PK V + I D N ++P+F + YEV + NT+ + V + ATD D S + Y LD+ + F ++ +G ++T N R + I A D P + + I + D+ P F ++ EN +++ +T A +++QV + ++ K + + + + +LD E+ +++ L + +G + + + V+D NDN P + N + T K V+ V A D D+G NG++ Y I ++ VF++D +GEI K LD + +L I +DS PK
Sbjct: 1549 TVSENKPTGTSVVKVTAYDRD-SGSNAELTYSIPSGVEMDKFSIDKHSGLIVT---NSILDREKKDTYFLTVHATGVSYPFRVSST--SVRINVMDRNDNPPKFISPVVTLKVPENS-PARLIYTLTVQDLDYGNNTKVLYSIMSGN---TDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFAN-------ITIFIEDQNDNPPVFQQSLYSST----ISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAAR-----FETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYII-----AEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPEN---SKVGSYITTVRARASSDAQVTYSIIS--GNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAF-KPRFVVKVTATDVDSGTNGKVTYSIWT---GNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPK 2154 HSP 13 Score: 108.227 bits (269), Expect = 1.211e-23 Identity = 150/574 (26.13%), Postives = 242/574 (42.16%), Query Frame = 2
Query: 683 LRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFT-------------KNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPN-DLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK-VPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPK-STDRSVLVHITDMNEYSPEFK---QLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFF--KIDHMSG-WIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIIN--KNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD 2320
+ K+ LD E Y LT+ + +++ VQD NDN P F K+F + I ++D GS + +Y SG++G V I + D DL +N++S + ++ +L ++ + SD NP + + ITVED N+ P + +S + + EN G +++ + SD DIG N+++ ++T S + +VR D+E+ + +K D GS + S+ V + + D+N+ +P L + EN T+V +++ +D D + +L E G +F K D ++ I LDRE + A D P T + + D ND AP F E V EN L+ + A D D G+NS++ + + T + + G I T LDRE L V V D+G P++ + +V V + D NDN P + + YN + N V+ + A D D GEN I Y I P P F LD G + + LD +
Sbjct: 14 ITTKTVLDREKVSAYNLTIVEFSTPPKS-YTVLVYVQDLNDNSPSFVRGTSAKLVVFENDKDFRQKLIAVDSDFGSN--STQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASS--------IGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIP--ENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVR-LDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTL-EGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSS-----YNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTP----NTPFF-LDPRKGLVTNSRTLDHE 562
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 191.43 bits (485), Expect = 2.588e-49 Identity = 212/735 (28.84%), Postives = 341/735 (46.39%), Query Frame = 2
Query: 263 KLKFSSLKFNVDSQFLQIND-NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQIN--DLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD-------SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEF--TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDS---ATKPKMVMLKLIINN 2398
++K+ L + D+ I + +G VT+ K++D E + + +V D+ + S TV ++I D+ND TP FS + T+RE +PVN ++ A D D + E + S N + +R+K +LDYE + L + A D+ + D LI D NDN P F + ++ I EN G V AYDKD G G + ++ NDL F IN N+G I ++ L + +TF + A+D P KE + IT+ DIN+ P + + EN+ G +++ +K D D G + V + + S D + L +L+ + ++ + V S+ +D S+ V V++TD N ++PEFK+ Y ++E+ + T VL + ATDRD A I YS+ F +D +G IKT LDRE ++T F A D + A + + + I D NDN P+F + P + V+E++ + ++A+DAD G N+Q+ + + A + Q F++ S +G I TL+ LDRET Y L V D+G P S V V + D D+ P + P E + V+TV+A D + Y I + NS Q VF ++ ++G I+ + +LD++ + LT+ A+ S MV LK I +N
Sbjct: 162 EVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYT------------LQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNG--EVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALI----DVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSF-MQNDL----PFSINENTGGISIKEELDREKVPKFTFGIKARDKGV--PFKEGTAQITITLLDINDNPPKFS--QEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVY-SIVSSSGHDRCFRINPQGLITLSC--TLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPE-FSVDETTGVIKTAG-SLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVF-LKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQI----IYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKP---LYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSI--VRGNSPQ-VFDINPNTGAIQTLMKLDYETQSEYRLTVRATLSPFFTETTVMVYLKDINDN 850 HSP 2 Score: 177.948 bits (450), Expect = 4.237e-45 Identity = 189/731 (25.85%), Postives = 320/731 (43.78%), Query Frame = 2
Query: 236 GNIKYAL-PDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELI---IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNP-QKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GAASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPKMVMLKL 2386
G I+Y++ P + S+ F++D QI G +T K+ +D E L ++ F + K + + + + D+NDN P+F + E + + A D D + ++ L + + +K +LD E Y L ++A D+ + + I + D ND P F+K Y +I E+ LV TV A D D G G V + I + ND++ F IN +GE+R++++L ++ V A+D P + V+I + D+N+ P +S++ + + EN G ++ D D G N ++ ++ + F + EN ++ D E + IK D G P K + + + D+N+ P+F Q Y S+ EN+ T VLQ+ A D D G ++ YS+ F+I+ + T + L+ VF+ A D + ++T + V + D N +AP F VKE+ + + ATD D G+N+++ + + + FSV + G I+T SLDRE ++Y EV D G + + V + + D NDN P ++ P + E + I V+ V A D D G+N +I Y + Q F++D G IR +K LD + I ELT++A+D T P +K+
Sbjct: 53 GMIRYSMSPSQNLMSATYFSID----QIT--GVITTKRGLDREFLDRH----------FFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMK-KLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNF---FSINRINGEVRVKQKLDYEMIGVFNLLVTAQDK--GQPFLYNQTTVDIALIDVNDNAP--QFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFM-QNDLPFSI---NENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRINPQG--LITLSCTLNYNTKHVYVFSVSASDGML---SSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPE-------FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKP---SYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFAS--NGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKV 738 HSP 3 Score: 164.466 bits (415), Expect = 5.542e-41 Identity = 199/729 (27.30%), Postives = 327/729 (44.86%), Query Frame = 2
Query: 200 TVKEEFKPNQFIGNIKYALPDKLKFSSLKFNV----DSQFLQIND-NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLF-STIEQTITLRESLPVNYSMSLE----SAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVREN-TLPGNLITIKVSDNDIGMNSKVNCELQT---ESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSL--DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVS-KEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
T++E+ NQ + ++ D+ + F + D F IN NG+V +K+++D E + G F V D+ + TV++ + D+NDN P F S+ QT+ +P NY++ E A+D+D I ++ + F ++ + + +K ELD E ++ +KA D+ ++ I + D NDN P F++ Y SI EN+ G+ V+ V A D DSG +V Y+I + + D + F IN G I L L N + +Y F V A D ++ V + V D N + P S + EV+E+ +L +++T+ +D D G N+K++ + T E +D E + + S D E + TD G P V +HI D+N+ P F + YE +RE+ +V++++A+D D A I YS + G+ F ID G I+T LDRE I A D P A+ K+ V +ED D+ P+F + E TV E+ + + A K + E ++ ++ R Q +F ++ G I+TL LD ET Y L V P T T V V + D NDN P + N+ E + A+D D + ++ +++ + N+K+ V +L+ SGE+ + K+L
Sbjct: 242 TIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMI--------GVF----NLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTM-----IPENYAVGQEFYRVQAYDKDHGTNGEI-TFSFMQNDLPFSINENTG---GISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVV-YSIVSSSGHD--RCFRINPQ-GLITLSCTLNYNTKHVYVFSVSASDGMLSS----TALVYVNVTDSNTHAPEFKRRSYS--AEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVD-------ETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLK-PLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKA----KSQDLSPETGMMYSIVRGNSPQ-VFDINPNTGAIQTLMKLDYETQSEYRLTVRATLS---PFFTETTVMVYLKDINDNTPVL---EAFHMNINVQEGKVPPEARYKIPAYDPDVSD--KLTFKVM--EGNAKEWV-TLNATSGELSVNKKL 915 HSP 4 Score: 158.688 bits (400), Expect = 4.246e-39 Identity = 169/627 (26.95%), Postives = 275/627 (43.86%), Query Frame = 2
Query: 491 DNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQIS--LRLKSELDYETRKQYRLTLKACDRDSCTDK---ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNI---DAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIA--ILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTN-VTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE 2329
+N P FS +++ ++ E V ++ SA D D S N + Y + S N QI+ + K LD E ++ +KA D + + +L I+V D NDN PIF +N Y I E+ G V+ V A D DSG G V Y I D N F I SG + + ++L + YT V A+D N P+ V V+IT+ D+N+ P + + S R +V N L + T++ +D D G N +V E+ + + ++F + + + + D+E V + + D G P +V + + D+N+ +P+F ++ + EN A + ++ A D+D I +S + F I+ +G I K LDRE + F A D V T +I +T+ D NDN P F T + EN + ++ A D D G + ++ ++ + F ++ +G I +L+ T Y V D M +ST V V V D N + P++ + + + V+TV A D D G N +I Y I P FS+DE +G I+ LD ++++
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPD-SGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNS-----AFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQG-NPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQL---VTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVK--QKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDLP-FSINENTGGISIKE-ELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTN-----VVYSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDG----MLSSTALVYVNVTDSNTHAPEFKRR---SYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPE-----FSVDETTGVIKTAGSLDREKVD 610
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO30364 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T100]) HSP 1 Score: 189.504 bits (480), Expect = 9.092e-49 Identity = 193/643 (30.02%), Postives = 307/643 (47.74%), Query Frame = 2
Query: 485 LNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD-----RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAF--FKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT---RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKP 2365
+ND +PLF + + ES + +A DRD N I Y + KF + S I + S LD E + Y L + A + +D+ T ++ I V D D+KP F + V + EN G+ V + A DKD GD + Y+I + L F I++ +GEIR L Y V AKDS N + + V + VED+N+ PV ++ +E E + G +++ +K D DIG N+ V + E+ D+ + + SL S + D E + + +I+ TDSG P KS+ SV + + D+N+ SP F Y +REN T VL + A+D+D + + S G + F ID +G I T+ L+RE + A D+ + TT++I+T+ D ND+ P F F+V+E++ +GR+ TD D +N++V + + +FSV++ G I T +LDRE SYTL + +D G + ++T+V + + D NDNKP + YN+T + K ++V + A D D G NG+ Y+I VF +D ++G I + +LD+++ LT+ A D T P
Sbjct: 1082 INDESPLFEKSMYYVNVSESASRGIVIGRVTATDRD-EGINAIIFYSSNGAEAKFYVSRSTGDII---VDSPLDREFKNVYILNVTAANIVAGAQDTTT--QVHITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSIANGDPYGL---FTIDNVTGEIRTVAELDRENVTQYELFVQAKDS--VNLVSDLLKVVVQVEDVNDNPPVFSM--PGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSI-VENVTDYVTVNAITGVISLGSSQ-LDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYTRFAIDPDTGNITTRE-PLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYI-----SSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFS-----KSVYNVTLRESVFLKTQVVQVI-ATDPDEGANGQFTYKI---TAGDTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPP 1692 HSP 2 Score: 167.933 bits (424), Expect = 4.406e-42 Identity = 166/623 (26.65%), Postives = 287/623 (46.07%), Query Frame = 2
Query: 464 VNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDK--ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRL-ERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD--GAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFG-VIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEY-NITRIINKNELVMTVQAFDTDA-GENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
V++ + D+ D+ P F++ T+ L E+ + +++ +A D+D SY + + + + L T +R +ELD E QY L ++A D + ++++ V+D NDN P+F+ Y + E + G+ ++ V A D D GD V+Y+I N D + +N+ +G I L +L + + F + A DS P K V I + DIN+ PV +T+ VREN G ++ + SD D+G N+K++ L S + + + ++ + + E + +++ DS + V++ +TD N++ P+F Q Y S+RE+ V ++ TD D A +RY + + + + I + LDRE + A D + + T +++TIED NDN P+F + T++E++ + ++ ATD D+G N Q + + + +F + + G I LD E Y L V +D G P+ + V + V D +DN P + P Y N+TR V+TV A D DA + R+ YRI + +S +F + E SG I L
Sbjct: 1178 VHITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIG---DTISYSIAN-GDPYGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSI-VENVTDYVT---VNAITGVISLGSSQLDREVEEYFNFTIRATDSGV--PSKSSTASVAIKLVDINDNSPVFN--NTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVL---SGVLYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKIT-----AGDTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTR----GHHVITVNATDIDAEASHKRVYYRIESGNTDS---MFLIGEQSGVITL 1773 HSP 3 Score: 162.54 bits (410), Expect = 1.935e-40 Identity = 184/680 (27.06%), Postives = 306/680 (45.00%), Query Frame = 2
Query: 470 LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQIS----LRLKSELDYETRKQYRLTLKACDRDSC---TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYY-PVIAILSTNERVEVREN-TLPGNLIT--IKVSDND------------IGMNSK------------VNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPK-STDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDA---YVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVM-TVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIR-----LVKELDFDQIELTIIASDSATKP 2365
L ++D NDN P+F+ + E+ V ++ SA D D ++++ YK SN T F S L L LD+E + Y L + A D + +II+V D +D P F ++FY I ENT GS VVTV A D D G ++Y I + N + F I+SN+G I + + A + + F + K S+ +P + N P A L + +VRE+ LPG +++ ++V+D D +G +S +N L E +I+F E +D+ +G+ + + T++ + K S + SV + + ++N+ P F + Y ++ E T + + ATD D ++ Y L A+F ++ +G I + LD + + F+ D Y + AT + VT++D NDN P F +P + + EN+ + ++ ++TATD D G N ++ F + + FS++ G + T + LDRET +YTL V D G +TV VLDENDN PQ + I NI+ +++ ++ A D DAG NG++ Y + F+L+ +G ++ L +EL D +L I +D+ + P
Sbjct: 34 LIVDDYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQ-YKF---SNATATQTPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEIISGNSDGV---FTIDSNTGVITVNGSIDAEKTDV--FRITVKASEVPDPNSNTTVTVVVTVVDVNDNRP--AFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSDKFAIDPTSGTLYINKTLDYEKQINFTF--DWERGCGSGGGSGWDW-TGRGEEKKVVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQAAYFSVNADNGTISAAQI-LDYDTLRQYQFSLVVKDGGGFYQEIAIAT--VTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNI-----SAGDDGGHFSINGSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITT--NISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR-----FTLNSATGRLQISPTGLDRELK-DSYDLIINVTDNGSPP 683 HSP 4 Score: 160.229 bits (404), Expect = 1.241e-39 Identity = 182/655 (27.79%), Postives = 292/655 (44.58%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS-SNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACD-----RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEK-VPVEITVEDINNYYPVIAILSTNERVEVRENT-LPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIR--YSLDEKGK--AFFKIDHMSGWIK---TKNVVLDREVIETIVFNAFAHDAYVDPFTATTKI-----------IVTIEDENDNAPIF---GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNP-NPINPEYNITRIINKN----ELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
+ +V +++ D+NDN+P+F+ + +RE+ P + + +A D+D ++ SY L +F +D ++ + L+ E Y LTL+A D R+ T +II V D ND+ P FT++ Y S+ E+ G V V D+D D V Y I + N + F +N +G I L Q YT + AKD P E V IT+ED+N+ P+ + N V +RE+ L ++ + +D D G N + ++ D + L ++ + D+E + + ++ D G+PP + V +H++D+++ +P F + Y L EN V+ +NATD D AS + Y E G + F I SG I T + L+RE H Y A +++ ++T+ D NDNAP F + I+ I + A D D+G + ++ F T+ E +F + +K G + + LDRE Y+L V DKG+ +++S V + VLD NDN P P + + PE T + +N V V A D D I Y I N + +Q F L+E SGE+R LD
Sbjct: 1382 TASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKL-SYVLSGVLYTRFAIDPDTG---NITTREPLNREETGSYTLTLRAVDSAIRAREGTT--RVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLM---FSVNETTGIISTTSTLDREQNASYTLIITAKDHGI--PALESNTSVMITIEDVNDNKPLFSKSVYN--VTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTGLITIKA--KLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVITLNCTPSGCLNRE----------THARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIF----TIVSGNE-NGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLDT--KNLIYYYITNTE---EQKYFILNETSGELRTRITLD 2001 HSP 5 Score: 159.073 bits (401), Expect = 2.379e-39 Identity = 177/672 (26.34%), Postives = 294/672 (43.75%), Query Frame = 2
Query: 395 QFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDR---DSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLD-EKGKA--FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVK--ENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQ-----SLDRETFESYTLEVGVRDKGKYPMATS-TNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSA 2356
Q+ F+Q K VN +D L V +Q+ D+NDN P+FS TI E P S+ A D D +N Y + ++ + + ISL S+LD E + + T++A D + + I + D NDN P+F Y + EN G+ V+ V A DKD G + Y + L F I+ ++G I L + YT + A DS ++ V ITV D N++ P + VRE+ G+ + + +D DI N++V + + + + E +++ + D E + I D G P ++ SV++ I D+N+ P F + +Y V+LRE+ T+V+Q+ ATD D A+ +++ G F ID +G I K LD E A D P T + + + D +DNAP+F P ++ + EN+ + + ATD D + + + +++ +F + ++ + TL L+RET Y L+V + S + VLD NDN P++ + + + T I + ++TV+A D D GE+G I + I + N VF +D +G + + LD + L ++A D
Sbjct: 1260 QYELFVQAKDSVNLVSDL---LKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADI-GDNAAVLYSIVENVTDYVTVNAITGVISLG-SSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGV----LYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAI-RAREGTTRVIITVTDANDHVP--QFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNT--SLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTGLITIK-AKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHK-PRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIES----GNTDSMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPIT-DATILTVKAQDGDEGESGEIIFTIVSGNENG---VFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKG 1907 HSP 6 Score: 145.976 bits (367), Expect = 2.731e-35 Identity = 184/689 (26.71%), Postives = 296/689 (42.96%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNV---DSQFLQIN-DNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSL---TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE--DSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDK---ELIIDVQDENDNKPIFTKNF-YKVSILENTDTGS-LVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLY-TFHVVAKDSDFNNP-QKEKVPVEITVEDINNYYPVI------AILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVR-SFDFESGQVKSAS---------IKCTDSGSP---PKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFF--------------KIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT-VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATST--NVTVKVLDENDNKPQW 2104
N T+ EE P I +I D F +L + + + + +N DNG ++ + +D +TL Q Q ++V D F + TV + + D+NDN P F+ + T + E+LP + +A D+D S EN S+ + D F ++ S + ELD ET Y LT+ A D + +L ++V DENDN P T +I E G+ L+ ++ A D D+G G + Y++ + F +NS +G RL+ R+L ++ ++ +D +P V +T+ D+N+ P ++ + V+ T+ LI I +D D N KV L + F+L L SVR D ES Q+ + I TD +P KS V + + D N+ SP+F+ YE L E + V+Q++ATD+D L+ KGK + K+ W K KN VL +E ++ T +++ ++D NDN P+F V EN + + R+ A+D D+G N ++ + L T K + I +V+ E I +DRE ++ L V D+G+ P + T V + V DENDN PQ+
Sbjct: 395 NYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQAAYFSVNADNGTISAAQILDYDTLRQ------------YQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKD-SGENGRLSFNISAGDDGGHFSINGSGL----VTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGD-----SRFTLNSATG--RLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFFRLDPVTGEL----SVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQD--------LEYKGKVIYNITDGDENRKCEVEKLVRHYNWHK-KNCVLCKESKCSV---------------ERTYVVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKL--TNGNKDDAFSINNVTGE--ITVAGVIDREAVHTFVLTVQAEDQGE-PSSRKTFAEVVITVKDENDNFPQF 1026 HSP 7 Score: 130.183 bits (326), Expect = 1.776e-30 Identity = 180/721 (24.97%), Postives = 311/721 (43.13%), Query Frame = 2
Query: 305 FLQIND-NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQISLRLKSELDYETRKQYRLTLKAC---DRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVT----VNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTF-----------------------HVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTD-RSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSL-----DEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMI-----STRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIE-TLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINK-----NELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELD 2314
F +N NG++TL +D E + + L + + TV +++ D++D P F + E+ P+ ++ A D D N I + +S+ F +D++ + + +D E +R+T+KA D +S T +++ V D NDN+P F ++ Y + E+ VV+ V DK+ ++ + + A +D F I+ SG + + + L ++ +TF VVA ++D + V +T+ ++N+ P+ A S N ++ E PG I I +D D+G + EL+ F + + ++++ + D+++ + S+ D G + +V V + D+N+ PEF + Y + EN T V Q+ ATD+D + R S D+ G F I+ SG + T LDRE I T A+D V ++ V + DENDN P + T+ N+ T L+ + A D D G+N Q+ + + +R F++ S G ++ + LDRE +SY L + V D G P ST V V +LD NDN P + +PNP +++ N+ ++ + A D DA NG++ Y + + F LD +GE+ + KELD
Sbjct: 95 FFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLE----------SRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEIISGNSDGVFTIDSNTG---VITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSD-----KFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMD--EEITPGTHIADITATDADLGTFGALTYELRGGQAAYFSV---NADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGH--FSING-SGLVTTARE-LDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTP--QITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR-------FTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAF-DPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLS----GDEHGFFRLDPVTGELSVRKELD 774 HSP 8 Score: 129.798 bits (325), Expect = 2.539e-30 Identity = 180/686 (26.24%), Postives = 289/686 (42.13%), Query Frame = 2
Query: 446 FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELI----IDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIA---ILSTNERVEVRENTLPGNLI--TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEF------KQLIYEVSLRENTAT-NTKVLQLNATDRDGAAS--IRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIET---------IVFNAFAHDAYV---DPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRL---------IGRLTATDADKGNNSQVEF-VLLKTLARKQEVQKI---FSVSKEGFI---ETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSA 2356
F + +V L + ++NDN P+F+ T+ E + ++ +A D D + +Y+L + + IS LDY+T +QY+ +L D + I + +QD NDN P FT Y I EN G++V V A DKDSG+ G + +NI A +D F IN SG + R L YT V A D ++ K V + + V D N+ P I ++TN + E G ++ +I D D G N ++ + S D + S D E I TD+GSPP + +V V I D+N+ +P F Y +++ E T N ++ +NATD D A+ + YSL FF++D ++G + + LDRE + + + A D D +AT ++ +T+ D NDN+P F + TRL + +++ATD D +V + + RK EV+K+ ++ K+ + E+ S++R T V + V D NDN P + N ++ V+ V A D D G NG+I Y++ N +K FS++ +GEI + +D + + LT+ A D
Sbjct: 369 FSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGAL-TYELRGGQAAYFSVNADNGTIS--AAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDG---GHFSING-SGLVTTARELDRETIATYTLTVSAYDHGVSSRHKH-VQLTVNVLDENDNTPQITDGLTITTN----ISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSM---SGGDSRFTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFFRLDPVTGELSVRK-ELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQF--------QSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRKCEVEKLVRHYNWHKKNCVLCKESKCSVER-----------------------TYVVIYVDDVNDNDPVF---NQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTN---GNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQG 1001 HSP 9 Score: 127.102 bits (318), Expect = 2.039e-29 Identity = 163/581 (28.06%), Postives = 259/581 (44.58%), Query Frame = 2
Query: 776 LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQT--FGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE-KVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVL--QLNATDRDGAASIR---YSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFN-------------------------AFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKY--PMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIE---LTIIASDSATKPKMVMLKLIIN 2395
LI+D D NDN P+FT+ Y I EN G+ ++ ++A D DSG V Y ++ QT F +NS +GE+ L L + Y V+A+ D P+ E + V I V DI++ P L + E+ ENT G+ ++T++ D D+G+N+ + E+ + + + + ++ S D E V ++K ++ P +T +V+V + D+N+ P F Q +Y +RE+ A +V+ QL TD D R Y L F ID SG + N LD E F+ A D + F+A + +T+ + NDN P+F +T+ E + I +TATDAD G + + L A FSV+ + G I Q LD +T Y + V+D G + +A +T VTV + D NDN P++ + +I + +V V A D D+GENGR+ + I FS++ SG + +ELD + I LT+ A D + ++L +N
Sbjct: 34 LIVD--DYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKF---SNATATQTPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAE--DLGVPKLESRTTVIIEVTDISDMPP--RFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEIISGNSDGVFTIDSNTGVITVNG--SIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSDKFAIDPTSGTLYI-NKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTS-EKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQA------AYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIAT-VTVTLQDVNDNDPEFTG---MPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGH---FSIN-GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVN 587 HSP 10 Score: 120.553 bits (301), Expect = 1.664e-27 Identity = 178/711 (25.04%), Postives = 298/711 (41.91%), Query Frame = 2
Query: 326 GDVTLKKRIDLETLCQNSNICC-GQFLCFIQT---KVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE--LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVE--ITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRD-GAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVK--ENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNE--LVMTVQAFDTDAGENGRIKYRIHN-----PKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPK----MVMLKLI 2389
G+++++K +D E+ + N G+FL I ++DR ++ V++ + D NDN+P F + L E+ ++ SA D+D + ++ Y + D + + K + Y K+ C C+ + ++I V D NDN P+F ++ Y +LEN+ TG+ V+ V+A D+D G G + Y + N D F IN+ +GEI + + ++ ++TF + + D P K E ITV+D N+ +P + T E+ EN+ G+ IT+ V D I S ++ + LL +E IT +N+ SP F++ +Y V++ E+ + + ++ ATDRD G +I + +A F + +G I + LDRE + N A + TT++ +T+ D D+ P F TVK EN + ++TA D D G+ + +F++ G I T+ LDRE Y L V +D ++ V V+V D NDN P + P Y I E ++ V+A D D G+N + Y I N+ V SL G +L +E++ + TI A+DS K V +KL+
Sbjct: 765 GELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSA--TVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKV-IYNITDGDENRKCEVEKLVR---------HYNWHKK---NCVLCKESKCSVERTYVVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDD---AFSINNVTGEITVAGVI--DREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSF--TGYEGEIAENSPVGSTITM-VPDQKI---SSSTLRPRSSPRAPAALLTAREKR---------------------------------------PITLINDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYSSNGAEAKFYVSRSTGDIIVDS-PLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNS-SSLTVKLSENASIGTNVTKITALDKDIGDTISYSIA-------NGDPYGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNL-VSDLLKVVVQVEDVNDNPPVFSMPG-----YTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSIVENVTDYVTVNAITGVISL----GSSQLDREVE-EYFNFTIRATDSGVPSKSSTASVAIKLV 1390 HSP 11 Score: 105.531 bits (262), Expect = 7.981e-23 Identity = 178/669 (26.61%), Postives = 278/669 (41.55%), Query Frame = 2
Query: 452 DSLTVNLQINDLNDNTPLF------STIEQTITLRES-LPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYR---------LTLKACD-------RDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEI-RLERRLAANQRKLYTFH----VVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPP-KSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDS 2353
+S TV++ I D+NDNTP F S IT+ E +N ++ +A D D A ++ D F LD L ++ ELD E+ + R L + A D R S T + + I V+D NDN P F Y+ + E GS V+ V+A D+D G V+YNI T G + E+ +L R Y +H V+ K+S + E+ V I V+D+N+ PV + +V EN+ G ++ + SD D G N K+ +L +K D + ++A V D E+ +++ D G P + T V++ + D N+ P+F YE + EN+ + + +V D+++ + + + A TA K +T+ ND +P+F + V E+ +IGR+TATD D+G N+ + + + F VS+ G I LDRE Y L V + T+T V + V D D+KP + N + + + + I N V + A D D G+ I Y I N P +F++D +GEIR V ELD + Q EL + A DS
Sbjct: 686 NSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFFRLDPVTG---ELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVR-VSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNI----------TDGDENRKCEVEKLVRH--------YNWHKKNCVLCKESKCS---VERTYVVIYVDDVNDNDPVFN--QSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVAGV--IDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSFTGYEGEIAENSPVGSTI--------------------------------------TMVPDQKISSSTLRPRSSPRAPAALLTAREKRPITL--INDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFY-------SSNGAEAKFYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKP-YFNSSSLTVKLSENASIGTN--VTKITALDKDIGDT--ISYSIANGDPYG---LFTIDNVTGEIRTVAELDRENVTQYELFVQAKDS 1270
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 251.521 bits (641), Expect = 6.444e-69 Identity = 227/741 (30.63%), Postives = 355/741 (47.91%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVN-------LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE---DSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI------LSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENL------YSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA-FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNEL-VMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVK 2305
+ EE PN IG++ LPD K V S +L+++ G++ T + ID ETL N+ CF++ +V + D + + + +++ D+NDNTP FS+ T+++ E+ S+ A DRD S N + Y L D++ F L + K PQ+ + LD E + Y L ++ D + L I V D+NDN P F KN Y+ + EN+ G V+ V A D D+G G + Y++ +D + + I+ ++G I ++ + + L F+VVA+D N+ + K V I+++D N+ P I I + N + E+ G + ++VSD D G N+ V C + + + FQL E+ Y L + D+E + I DSG+P S+ S+ V +TD+N+ +P F + EV+ E+ KV+ + ATD D A + YS+ E A F+I+ +G I+ +N LDRE +E F A D V T T +++ +ED NDN P F + F+V ENM +G +T +DADKG NSQV TL + + K + G I + S DRE +YT + D G P ++ VT+ VLDENDN P P N Y + + + V V+A D DAG N + Y I P+ +F + +SGEI+L +
Sbjct: 45 LSEEQPPNTLIGSLAADLGLPDSGHL--YKLEVGSPYLRVDSKTGEIYTTEIPIDRETLSDCRNLFEDD-KCFLEFEVSITD---MVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRD-SGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIV--IGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDT-VQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNS-KSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGD--VPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLFEINSNTGEIRVRNQ-LDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQV------TLFVEPDNGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVT--KPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHG---LFQISHNSGEIKLAQ 760 HSP 2 Score: 129.028 bits (323), Expect = 7.826e-30 Identity = 121/457 (26.48%), Postives = 212/457 (46.39%), Query Frame = 2
Query: 1109 ITVEDINNYYPVIA--ILSTNERVEVRENTLPGNLITIKVS-DNDIGMNSKVNCELQTESKIDFQLLKKK------ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA--RKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPKMVMLKLIIN 2395
I V DIN+ P + IL+ + + ENT G L +I V+ D D G N L + QL + E + + + + D E +I+ D G PP+++ + + +TD N+ +P+F++ YE L EN+ VLQ+ A D D A+ I YSL + + +ID +G I K +V DRE + F A D + ++ ++ ++I+D+NDNAP G++ + E+M + + +D D+G N+ V V+ + + + ++ F++T LD E + Y +E+ D G ++++ ++ V+V D NDN P + +P E N + V+ V A D D+G N + Y I +S +F ++ ++GEIR+ +LD + + E + A+D K ++IN
Sbjct: 139 IEVLDINDNTPQFSSPILT----LSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDAN-QLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDTVQRLLRIDRSTGIIYVKGLV-DREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSF---SPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIE---SSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVIN 583 HSP 3 Score: 74.3294 bits (181), Expect = 5.410e-13 Identity = 78/332 (23.49%), Postives = 147/332 (44.28%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHI 1441
++ +Q+ D+NDNTP FS + E + A D D + +E S+ FE++++ +R++++LD E ++Y + A D+ + ++I+V+D NDN P F + Y S+ EN + V V D D G+ V ++ N +IQ G + I +R + YTF + A D+ + P+ V V I V D N+ P + + + ++ ++ P + +K D D G+N+++ + + L + N + + F + + ++ +D G PP+ T + LVH+
Sbjct: 474 SLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLFEINSNTG---EIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFVEPDNGKFIIQN-GTGTILSSISFDRE----KESTYTFRLKAVDAG-DPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNP--HGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHT--TALVHV 792
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 251.906 bits (642), Expect = 1.490e-68 Identity = 227/741 (30.63%), Postives = 355/741 (47.91%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIK--YALPDKLKFSSLKFNVDSQFLQIND-NGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVN-------LQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLE---DSSNKFELDTS-----KFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI------LSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENL------YSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA-FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNEL-VMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVK 2305
+ EE PN IG++ LPD K V S +L+++ G++ T + ID ETL N+ CF++ +V + D + + + +++ D+NDNTP FS+ T+++ E+ S+ A DRD S N + Y L D++ F L + K PQ+ + LD E + Y L ++ D + L I V D+NDN P F KN Y+ + EN+ G V+ V A D D+G G + Y++ +D + + I+ ++G I ++ + + L F+VVA+D N+ + K V I+++D N+ P I I + N + E+ G + ++VSD D G N+ V C + + + FQL E+ Y L + D+E + I DSG+P S+ S+ V +TD+N+ +P F + EV+ E+ KV+ + ATD D A + YS+ E A F+I+ +G I+ +N LDRE +E F A D V T T +++ +ED NDN P F + F+V ENM +G +T +DADKG NSQV TL + + K + G I + S DRE +YT + D G P ++ VT+ VLDENDN P P N Y + + + V V+A D DAG N + Y I P+ +F + +SGEI+L +
Sbjct: 45 LSEEQPPNTLIGSLAADLGLPDSGHL--YKLEVGSPYLRVDSKTGEIYTTEIPIDRETLSDCRNLFEDD-KCFLEFEVSITD---MVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRD-SGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIV--IGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDT-VQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNS-KSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGD--VPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLFEINSNTGEIRVRNQ-LDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQV------TLFVEPDNGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVT--KPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHG---LFQISHNSGEIKLAQ 760 HSP 2 Score: 129.413 bits (324), Expect = 7.800e-30 Identity = 121/457 (26.48%), Postives = 212/457 (46.39%), Query Frame = 2
Query: 1109 ITVEDINNYYPVIA--ILSTNERVEVRENTLPGNLITIKVS-DNDIGMNSKVNCELQTESKIDFQLLKKK------ENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAAS--IRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPI-----FGVIPE----FTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLA--RKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPKMVMLKLIIN 2395
I V DIN+ P + IL+ + + ENT G L +I V+ D D G N L + QL + E + + + + D E +I+ D G PP+++ + + +TD N+ +P+F++ YE L EN+ VLQ+ A D D A+ I YSL + + +ID +G I K +V DRE + F A D + ++ ++ ++I+D+NDNAP G++ + E+M + + +D D+G N+ V V+ + + + ++ F++T LD E + Y +E+ D G ++++ ++ V+V D NDN P + +P E N + V+ V A D D+G N + Y I +S +F ++ ++GEIR+ +LD + + E + A+D K ++IN
Sbjct: 139 IEVLDINDNTPQFSSPILT----LSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDAN-QLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDTVQRLLRIDRSTGIIYVKGLV-DREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSF---SPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIE---SSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVIN 583 HSP 3 Score: 74.7146 bits (182), Expect = 5.076e-13 Identity = 82/346 (23.70%), Postives = 153/346 (44.22%), Query Frame = 2
Query: 422 VLVNDRNDFIDSL-TVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNK-FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKE---LIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHI 1441
V V+ N + S ++ +Q+ D+NDNTP FS + E + A D D + +E S+ FE++++ +R++++LD E ++Y + A D+ + ++I+V+D NDN P F + Y S+ EN + V V D D G+ V ++ N +IQ G + I +R + YTF + A D+ + P+ V V I V D N+ P + + + ++ ++ P + +K D D G+N+++ + + L + N + + F + + ++ +D G PP+ T + LVH+
Sbjct: 460 VAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLFEINSNTG---EIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFVEPDNGKFIIQN-GTGTILSSISFDRE----KESTYTFRLKAVDAG-DPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNP--HGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHT--TALVHV 792
BLAST of Protocadherin vs. Ensembl Medaka
Match: ENSORLT00000005325.2 (protocadherin-16 [Source:NCBI gene;Acc:101171352]) HSP 1 Score: 246.128 bits (627), Expect = 4.089e-66 Identity = 223/762 (29.27%), Postives = 354/762 (46.46%), Query Frame = 2
Query: 98 YSLIKPKFSMMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDN-------GDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDS--SNKFELDT----SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAI--LSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKE-GFIETLQSLDR-ETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKEL 2311
+SL+ + + F+IL + + L + E +G+I LP + + L F D + + + G +T K+R+D E S F+ T + ++ V++ +ND+ND+ P F + + + E V SL+ A D D + + Y +++ + F+L++ +K + L + LD E R Y L ++A D S L + V D ND+ P+F ++ Y I E+ GS ++ V A D+D GD GLV+Y I+ D + F I+ SG I L R L ++++ V A+D + + P+ V I V D N+ P + I LS + + E PG + I V+D D G + VN L+ F L K +Y + + D E + TDSG+PP + S + +TD+N+ P F Q Y ++ E + VLQ+ A D+D +RYSL KGK +F ID ++G I T LD E A D P ++T K+ + ++D NDNAP+F +VKEN + ++ATD D+G+ + + L TL VQ F+++K+ G + T +LDR E E Y L V D G ++++ V VKV+D NDN+P + P+ +++ V+ V A D DAGENGRI YR P P F+L++D+G I L + L
Sbjct: 5 FSLLCQQKPFLYAFVIL-----LQSTLVLGVLELQLDEGQPAGTIVGDISAGLPPG-ETARLYFISDHEGTGVGSDLDIDETTGIITTKRRLDREERDHYS------FIAVTMTGI----------TIEVSITVNDINDHAPEFPKKKALLKIPEHTVVGTRFSLDPATDAD-KDQLTTQGYAIKEGNVGHMFKLESKRSANKVLYLDLVVSGLLDREKRSSYSLVIEAFDGGSPRRVGFMTLEVTVTDINDHAPVFNQSRYHAIISESLPQGSSILQVFAADEDEGDNGLVLYEINR-RQSDPERYFVIDLKSGVITLNRPLDYELKRVHELVVQARD-NASQPEVTNAFVTIHVRDFNDNQPTMTIIFLSEDGSPRISEGAQPGQYVARISVTDPDYGEYANVNVSLEGGDG-KFALTTKDSIIYLIYVDQVLDREERDSYDLRVMATDSGTPPLRAESSFTIQVTDVNDNPPLFDQQAYRQTIPEVVYPGSFVLQVTARDKDQGPNGDVRYSL-LKGKKWFSIDPITGIITTAT-ALDFESEPAPSVTVIATDGGRPPLSSTAKVDIVVQDVNDNAPVFSSNFYNVSVKENTPAGTCFLEVSATDEDRGSFGTITYAL--TLKSGGTVQTPFTINKQTGQLCTASALDRDEGLEKYDLTVTATDGGG--LSSAVGVRVKVMDINDNRPTFY---PVLYTVSLSTHSAPGTSVVKVTANDPDAGENGRITYRT---VPGGSSPFFTLNKDTGVISLSRSL 728 HSP 2 Score: 179.104 bits (453), Expect = 5.070e-45 Identity = 173/656 (26.37%), Postives = 310/656 (47.26%), Query Frame = 2
Query: 404 CFIQTKVLVN--DRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKV-PVEITVEDINNYYPVIAILSTNERVEVRENTLPGN-LITIKVSDNDIGMNSKVNCE-------------LQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKA-FFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
F QTK++V DR T+ + I D NDN+P + Q I + E+ + ++L + D D S + L D + + ++ + + LD+E + Y +T++A D T+ + I V+D NDN P+FT + Y++S+ E+T GS V+TV A D+DSG+ G V Y + + + F I+ ++G + + R + + + ++V + SD +P + V++ + DIN+ PV + R V E+T PG+ L+ + DND+ S+ NC Q ES + F + + + +L DFE+ + + ++ +D G P +S+ + L+ I D+N+ P F + Y V+L E + T++++L ATD D A ++Y++ + F ID +G ++ + LDRE T V A D + A +IV ++D NDN P F V T++EN+ + + L A D D G Q+++ +++ R + F + + G + + D E S+ D G + + + V V V E++ P + + + + + K + + V A D D G +G + Y + P+S P F +++ +G I L
Sbjct: 2216 IFTQTKLVVTATDRGSPRLAGLATLTVIIIDQNDNSPTIP-LPQEIRIPENTLIGTEITLVTGNDVDSSPA--LSYSLLLDPTALGKFGIHRYTG-GVSITGPLDFEEKTWYTVTVQATDSQHQTEANITIVVEDINDNAPLFTHDLYQISLPEHTPPGSAVITVTATDRDSGENGRVNYRVMSSTQ----EGFYIDPSNGTLFINHRAEFDPERP-SVNIVIEASDGGSPALSSLTTVQVHISDINDNAPVFH--QSEYRAMVSEDTFPGSTLLIFEAFDNDL---SRENCGFDFAIANGNEGNVFQIESSVRFLEGRGFQTVGTLLLAEGLDFETKSLYNLTVVVSDRGVPQRSSSVAALITIGDVNDNPPVFSRPEYTVALSEGAVSGTEIIRLTATDPDSTPNAEVQYTISSGDEMNLFSIDQWTGALRLQR-ALDREHQSTHVVIIQATDG--QGYFALVPVIVDVKDVNDNHPYFPVETLTATIQENLPANSPVTVLHAIDHDTGVFGQLKYYMME---RSGSGRDSFVIEQNSGEVRSKIPFDFEKINSFNFVAVAVDSGNH--SATVTVQVFVTGEDEYDPLFTS---TDFAFEVPEGAKKGQSIGQVLARDEDGGVDGIVLYSL---LPSS--PYFDVNKTTGVIFL 2841 HSP 3 Score: 173.711 bits (439), Expect = 2.265e-43 Identity = 188/749 (25.10%), Postives = 315/749 (42.06%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLET--LCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCT---DKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVR---SFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIR----------YSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPF-TATTKIIVTIEDENDNAPIFGVIPEF-TVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPE-YNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIASDSAT 2359
N++VKE + D+ F ++ + L + G V I+ +T LC S + + L V D ++ V +++ D+NDN P F + T++L S+ +A D D RI + S+ F ISL L + + + A D D T + + + + + + P+F + Y ++ E+ G+ V V A K G + Y+I + D D F ++S SG IR L + A+ + +P + V I++ DIN+ P S+ + + + I+ +D D G N +++ +L + + VR S ++S + D G+P S+ +++VHI + P F L Y V LREN NT+ LQ+ A +R+ + + Y L G A F I SGW+ ++ LDRE + + A + T + + VT+ DENDN+P F V+EN+++ GR++ATD D G N+++ + LL K F + S+ G I T +LDRE SY L V V+D G P + + + VLDEND+ P + + P + + + +V +V A D D GENG + Y + S+ FSL+ ++GE++ L + + T+ A+D T
Sbjct: 564 NVSVKENTPAGTCFLEVSATDEDRGSFGTITYA-----LTLKSGGTVQTPFTINKQTGQLCTASALDRDEGLEKYDLTVTATDGGGLSSAVGVRVKVMDINDNRPTFYPVLYTVSLSTHSAPGTSVVKVTANDPDAGENGRITYRTVPGGSSPFFTLNKDTGVISL--SRSLHSKANTVISMVITAVDGDGLTAPVNARVNVSIVGGSTSSPVFEQAQYFFTVSEDVLRGTAVGVVRAATKTGVSKG-IYYSISS-GDPD--GYFTVDSTSGTIRTALPLDHETCSSLDLEIQAR---YGSPPSYGISRVHISISDINDNAPTFLPSSSESLLLPEVTKMGTVIYRIQATDKDSGHNGQLSFDLISAGAAGSSGQRTFGIDRGSGEVRLIGSLSYDSVPRYDLQVIAKDGGAPQLSSTFTLVVHIQAQDAQGPNFDTLTYRVELRENAPLNTRFLQVRALNREASGNGGSSSSISSSISYRLRPDGDAAGFGIMPDSGWLFVRSS-LDREAKDMYLLTVLATSRHSGTGRTGSATVRVTVTDENDNSPRLSQERVFLAVRENLVAGTGFGRVSATDRDAGLNARLTYRLL-------HADKHFQINSQTGEISTRLALDREQQSSYQLFVVVQDGGTPPRSATGTAHISVLDENDHAPTFTHVRPDTERMFEVREGLPSGTMVGSVAAKDPDEGENGTVYYSLS----GSRVERFSLNPNTGELKTASPLRWAERAEYTFTLTAADHGT 1286 HSP 4 Score: 172.94 bits (437), Expect = 4.905e-43 Identity = 172/603 (28.52%), Postives = 272/603 (45.11%), Query Frame = 2
Query: 275 SSLKFNVDSQFLQIND-------NGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSN--KFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD---SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQT-ESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVD-PFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSV-SKEGFIETLQSLDRETFESYTLEVGVRDKG 2032
S L+++++ Q+ Q +D +G +T+++++D E+ +L T V+ S+T L + D NDN P+FS+ I++ E PV + + A D D R+ SY+++ +N +F L + SL + LD E ++ + LT+ A D T + L + V D ND P+F + + ++EN G+ V+ V A D+D G G + Y + F IN +G I + L A + Y V A+D P K V + V+D+N+ PV A + +EV EN L +K +D D G ++ ++ + DFQL + +L++ D E + + D GSP S +V V + D+N+ SP F + Y V + EN +VLQ++ATD D I Y L ++ F +D +G I T LDRE + + F FA D P ++ ++ VTI D NDNAP F P + S R++ + A D D G N V + R K FS+ S G I+ + L T TL V D+G
Sbjct: 1452 SELRYSIEHQWPQTSDLLALDPLSGVLTIRQQLDRES-------TPFLYLVVRATDQAVDLSQRRWGSVTARLFVKDENDNPPVFSS-PSAISVMEDQPVGFVILHVMAHDADEGENGRV-SYRIQSGNNAGRFSLSPNTG---SLSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLCVQVIDVNDEAPMFQQAEFGTHVMENKGPGTTVLKVTATDRDQGSNGHITYGGVTEDG------FVINPLTGVITTTKELDAELQNHYVLTVYARDGGL-PPNFAKAVVRVEVQDVNDNAPVFAKMWYG--LEVPENQPAVELCFVKATDPDSGPGGELEYKIAAGDPDGDFQLHSRTG---ALSTSHGLDREKKPKYTLEVVAVDRGSPALSATATVEVKVLDVNDNSPVFSKNSYTVEVLENAEEGYQVLQVSATDVDEGLNGKILYFLSQEADGAFAVDEDTGRITTA-APLDREKLASYNFRVFAVDLSPSVPINSSAQVKVTILDVNDNAPFFIQDPLIIEVSSRRSQRVLATMKAEDKDFGANGSVFY-------RFATPVKGFSINSLTGEIQATEPLGSLTQAQRTLIVEAMDQG 2022 HSP 5 Score: 171.4 bits (433), Expect = 1.177e-42 Identity = 163/560 (29.11%), Postives = 260/560 (46.43%), Query Frame = 2
Query: 689 LKSELDYETRKQYRLTLKACDRDSCTDK----ELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKD-SGDLGLVMYNIDA--PNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKE--KVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLIT-IKVSDNDIGMNSKVNCELQTESKID-FQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVI-PEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNE--LVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI 2326
L ELDYE Y L ++ D +L I+VQD ND+ P F+++ + I EN + G+ + A D+D SG + Y+I+ P DL+ ++ SG + + ++L V A D + Q+ V + V+D N+ PV S+ + V E+ G +I + D D G N +V+ +Q+ + F L N SL+ +++ D E +V + +I D G P ST + + V + D+N+ +P F+Q + + EN T VL++ ATDRD ++ + + F I+ ++G I T LD E+ V +A D + P A + V ++D NDNAP+F + V EN + L + ATD D G ++E+ +A S+ G + T LDRE YTLEV D+G ++ + V VKVLD NDN P + + Y + + N E V+ V A D D G NG+I Y + + F++DED+G I LD +++
Sbjct: 1371 LVRELDYEKGSSYTLHVEVSDFSKAFPNSYLVKLEINVQDSNDHAPQFSEDPVTIVIPENKEPGASIYAFQAGDQDGSGPNSELRYSIEHQWPQTSDLL---ALDPLSGVLTIRQQLDRESTPFLYLVVRATDQAVDLSQRRWGSVTARLFVKDENDNPPV---FSSPSAISVMEDQPVGFVILHVMAHDADEGENGRVSYRIQSGNNAGRFSL---SPNTGSLSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLCVQVIDVNDEAPMFQQAEFGTHVMENKGPGTTVLKVTATDRDQGSNGHITYGGVTEDGFVINPLTGVITTTK-ELDAELQNHYVLTVYARDGGLPPNFAKAVVRVEVQDVNDNAPVFAKMWYGLEVPENQPAVELC-FVKATDPDSGPGGELEY----KIAAGDPDGDFQLHSRTGALSTSHGLDREKKPKYTLEVVAVDRGSPALSATATVEVKVLDVNDNSPVFSKNS-----YTVEVLENAEEGYQVLQVSATDVDEGLNGKILYFLSQEADGA----FAVDEDTGRITTAAPLDREKL 1906 HSP 6 Score: 157.147 bits (396), Expect = 3.337e-38 Identity = 179/681 (26.28%), Postives = 308/681 (45.23%), Query Frame = 2
Query: 458 LTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDF-SAENRIESYKLEDSS--NKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNE--RVEVRENTLPGN-LITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA---ASIRYSLDEKGKA-FFKIDHMSGWIKTKNV----------VLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTV--KENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRD-KGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKN----ELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQI---ELTIIASDSATKPKMVMLKLIINN 2398
+ NL + D+NDN P F ++E+ Y M + D +N +Y ++ SS F++D S+ + +D E Q +L + A DR S L + + D+NDN P ++ I ENT G+ + V D DS + Y++ D + FGI+ +G + + L ++ YT V A DS + + + I VEDIN+ P L T++ ++ + E+T PG+ +IT+ +D D G N +VN + + ++ F + L+ + FD E V I+ +D GSP S+ +V VHI+D+N+ +P F Q Y + E+T + +L A D D + +++ + F+I+ +++ + LD E D V +++ ++TI D NDN P+F PE+TV E +S I RLTATD D N++V++ T++ E+ +FS+ + G + ++LDRE ++ + + D +G + + V V V D NDN P + P +T I +N V + A D D G G++KY + + S + F ++++SGE+R DF++I +A DS V +++ +
Sbjct: 2133 MAFNLVLQDVNDNLPRFQLQNYVAFMKEAQ--GYEMPIIQVVAEDVDQGQNGQVTYSIQSSSMSGLFKIDPVTG---SITTTAIMDREIFTQTKLVVTATDRGSPRLAGLATLTVIIIDQNDNSPTIPLP-QEIRIPENTLIGTEITLVTGNDVDSSPA--LSYSLLL--DPTALGKFGIHRYTGGVSITGPLDFEEKTWYTVTVQATDSQ----HQTEANITIVVEDINDNAP----LFTHDLYQISLPEHTPPGSAVITVTATDRDSGENGRVNYRVMSSTQEGFYIDPSNGTLF-INHRAEFDPERPSVNIV-IEASDGGSPALSSLTTVQVHISDINDNAPVFHQSEYRAMVSEDTFPGSTLLIFEAFDNDLSRENCGFDFAIANGNEGNVFQIESSVRFLEGRGFQTVGTLLLAEGLDFETKSLYNLTVVVSDRGVPQRSSSVAALITIGDVNDNPPVFSR-PEYTVALSEGAVSGTEIIRLTATDPDSTPNAEVQY----TISSGDEM-NLFSIDQWTGALRLQRALDREHQSTHVVIIQATDGQGYFALVP---VIVDVKDVNDNHPYF-------PVETLTATIQENLPANSPVTVLHAIDHDTGVFGQLKYYMME-RSGSGRDSFVIEQNSGEVRSKIPFDFEKINSFNFVAVAVDSGNHSATVTVQVFVTG 2776 HSP 7 Score: 156.762 bits (395), Expect = 4.131e-38 Identity = 178/746 (23.86%), Postives = 318/746 (42.63%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRND--FIDSLTVNLQINDLNDNTPLFSTIEQTITLRESL-PVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISL-RLKSELDYETRKQYRLTLKACDRD----SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQR-KLYTFHVVAKDSDFNNPQKEKVPVEITVEDINN----YYPVIAILSTNERVEVRENTLPG-NLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAA-SIRYSLDEKGK-AFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMIS--TRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSK-EGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQW--------MNPN-PINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDF---DQIELTIIAS 2347
+ E +P Q++ I PD +++++ +++ +G L + + L + + +V+ D + +Q+ D+NDN PLF T+ E + P ++ + + +A D+D + Y L F +D P + + LD+E+ +T+ A D S T K I+ VQD NDN P+F+ NFY VS+ ENT G+ + V+A D+D G G + Y + + + F IN +G++ L ++ + Y V A D V V + V DIN+ +YPV+ +S + ++ PG +++ + +D D G N ++ F L K + SL+ RS ++ V S I D + V V I + SP F+Q Y ++ E+ T V + A + G + I YS+ +F +D SG I+T + LD E ++ A P +++ ++I D NDNAP F ++ ++ +I R+ ATD D G+N Q+ F L+ A Q+ F + + G + + SL ++ Y L+V +D G ++++ + V + ++ P + + N P+N + R +N+ + + I YR+ +P+ F + DSG + + LD D LT++A+
Sbjct: 358 ISEGAQPGQYVARISVTDPDYGEYANVNVSLE------GGDGKFALTTKDSIIYLIYVDQVLDREERDSYDLRVMATDSGTPPLRAESSFTIQVTDVNDNPPLFDQQAYRQTIPEVVYPGSFVLQV-TARDKDQGPNGDVR-YSLLKGKKWFSID----PITGIITTATALDFESEPAPSVTVIATDGGRPPLSSTAKVDIV-VQDVNDNAPVFSSNFYNVSVKENTPAGTCFLEVSATDEDRGSFGTITYALTLKSGGTVQTPFTINKQTGQLCTASALDRDEGLEKYDLTVTATD---GGGLSSAVGVRVKVMDINDNRPTFYPVLYTVS------LSTHSAPGTSVVKVTANDPDAGENGRITYRTVPGGSSPFFTLNKDTGVISLS--RSLHSKANTVISMVITAVDGDGLTAPVNARVNVSIVGGSTSSPVFEQAQYFFTVSEDVLRGTAVGVVRAATKTGVSKGIYYSISSGDPDGYFTVDSTSGTIRTA-LPLDHETCSSLDLEIQARYGS-PPSYGISRVHISISDINDNAPTFLPSSSESLLLPEVTKMGTVIYRIQATDKDSGHNGQLSFDLISAGAAGSSGQRTFGIDRGSGEVRLIGSLSYDSVPRYDLQVIAKDGGAPQLSSTFTLVVHIQAQDAQGPNFDTLTYRVELRENAPLNTRFLQVRALNREASGNGGSSSSISS----SISYRL---RPDGDAAGFGIMPDSGWLFVRSSLDREAKDMYLLTVLAT 1070 HSP 8 Score: 122.094 bits (305), Expect = 1.667e-27 Identity = 159/659 (24.13%), Postives = 263/659 (39.91%), Query Frame = 2
Query: 455 SLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSC----TDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNER-VEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG-KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT--RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD----QIELTIIASDSATKPKMVMLKLI 2389
+ TV +++ D+NDN+P+FS T+ + E+ Y + SA D D +I + +++ F +D + + LD E Y + A D + ++ + + D NDN P F ++ + + + + ++ T+ A DKD G G V Y P ++ F INS +GEI+ L + + T V A D V V E N S N R V ++EN G + ++ G ++ L + +K + + S DFE +K S ++ + + + D+N+ P F+ Y ++E ++Q+ A D D + YS+ FKID ++G I T ++DRE+ A D + V I D+NDN+P + E + EN + I +T D D +L T K + + G + LD E YT+ V D T N+T+ V D NDN P + + Y I+ V+TV A D D+GENGR+ YR+ +S Q F +D +G + + +FD + + I ASD + P + L +
Sbjct: 1822 TATVEVKVLDVNDNSPVFSKNSYTVEVLENAEEGYQVLQVSATDVDEGLNGKILYFLSQEADGAFAVDEDTG---RITTAAPLDREKLASYNFRVFAVDLSPSVPINSSAQVKVTILDVNDNAPFFIQDPLIIEV-SSRRSQRVLATMKAEDKDFGANGSVFYRFATP-----VKGFSINSLTGEIQATEPLGSLTQAQRTLIVEAMDQGSPAQSAHGVVVVYVKEVEYNGIR----FSKNARDVSIQENASKGTAVAQAQAEYPDGTRQGISYSLFSGNKKHLFKISSSTGEIWVESSNGLDFEETPRLRLVVKAETVSS---TSFMAFNLVLQDVNDNLPRFQLQNYVAFMKEAQGYEMPIIQVVAEDVDQGQNGQVTYSIQSSSMSGLFKIDPVTGSI-TTTAIMDREIFTQTKLVVTATDRGSPRLAGLATLTVIIIDQNDNSPTIPLPQEIRIPENTLIGTEITLVTGNDVDSSPALSYSLLLDPTALGKFGIHRY-----TGGVSITGPLDFEEKTWYTVTVQATDSQH---QTEANITIVVEDINDNAPLFT-----HDLYQISLPEHTPPGSAVITVTATDRDSGENGRVNYRVM----SSTQEGFYIDPSNGTLFINHRAEFDPERPSVNIVIEASDGGS-PALSSLTTV 2445 HSP 9 Score: 115.546 bits (288), Expect = 1.921e-25 Identity = 167/670 (24.93%), Postives = 274/670 (40.90%), Query Frame = 2
Query: 461 TVNLQINDLNDNTPLFSTI----EQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSS-NKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDS-CTDKELIIDVQDENDNKPIFTKNFYKVS--ILENTDTGSLVVTVNAYDKDSGDL--GLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPG-NLITIKVSDND-IGMNSKVNCELQTESKIDFQLLKKKENLYSLASVR-SFDFESGQVKSASIKCTDSG---SPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAF-FKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFT--VKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGF--------IETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKP----QWMNPNPINPEYNITRIINKNELVMT-VQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFD---QIELTIIASDSAT 2359
T ++ + D ND+ P F+ + E+ +RE LP + +A D D EN Y L S +F L+ + L+ S L + R +Y TL A D + I +Q + ++ I N ++ ++E T GS++ +V DK ++ G V Y + D D TF ++ G++ L R L + YT HV D P V +EI V+D N++ P + + + EN PG ++ + D D G NS++ ++ + LL + L + ++R D ES ++ TD S + + + + D N+ P F +S+ E+ +L + A D D + Y + A F + +G + LDRE E A D + + + + V + D ND AP+F EF V EN + ++TATD D+G+N + + V+++GF I T + LD E Y L V RD G P V V+V D NDN P W Y + N+ + + V+A D D+G G ++Y+I P+ F L +G + LD + + L ++A D +
Sbjct: 1186 TAHISVLDENDHAPTFTHVRPDTERMFEVREGLPSGTMVGSVAAKDPD-EGENGTVYYSLSGSRVERFSLNPNTG---ELKTASPLRWAERAEYTFTLTAADHGTPGLSSTCQIRIQVISSSRSIPKPNVLSMTLNVVEGTAPGSIIGSVGQVDKPESNVLEGQVTYLVVDGTDRD--GTFMVDRLRGDVYLVRELDYEKGSSYTLHVEVSDFSKAFPNSYLVKLEINVQDSNDHAPQFS--EDPVTIVIPENKEPGASIYAFQAGDQDGSGPNSELRYSIEHQWPQTSDLL-ALDPLSGVLTIRQQLDRESTPFLYLVVRATDQAVDLSQRRWGSVTARLFVKDENDNPPVFSSP-SAISVMEDQPVGFVILHVMAHDADEGENGRVSYRIQSGNNAGRFSLSPNTGSLSILK-ALDREEQEVFNLTIVAEDHGIPQLSTSQVLCVQVIDVNDEAPMFQQA-EFGTHVMENKGPGTTVLKVTATDRDQGSNGHITY---------------GGVTEDGFVINPLTGVITTTKELDAELQNHYVLTVYARDGGLPPNFAKAVVRVEVQDVNDNAPVFAKMW---------YGLEVPENQPAVELCFVKATDPDSGPGGELEYKIAAGDPDGD---FQLHSRTGALSTSHGLDREKKPKYTLEVVAVDRGS 1816 HSP 10 Score: 111.694 bits (278), Expect = 2.700e-24 Identity = 157/633 (24.80%), Postives = 282/633 (44.55%), Query Frame = 2
Query: 617 SYKLEDSSNK--FELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYT-FHVVAKDSDFNNPQKEKVP-VEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYS--LASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVV---LDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF------GVIPE----------FTVKENMISTRLIG-RLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNIT---RIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTII---ASDS----ATKPKMVMLKLIINNH 2401
SY L + K F++ +S +I + + LD+E + RL +KA S + + +QD NDN P F Y + E ++ V A D D G G V Y+I + + L F I+ +G I A R+++T +V +D +P+ + + + + D N+ P I + + + + ENTL G IT+ V+ ND+ + ++ L + L K + Y+ ++ DFE + +++ TDS T+ ++ + + D+N+ +P F +Y++SL E+T + V+ + ATDRD + Y + + F ID +G + + +R + ++ A D ++ T + V I D NDNAP+F ++ E F +N +S G + ++GN Q+E + R E + +V G + + LD ET Y L V V D+G ++S + + D NDN P + PEY + ++ E++ + A D D+ N ++Y I + + +FS+D+ +G +RL + LD + ++ A+D A P +V +K + +NH
Sbjct: 2081 SYSLFSGNKKHLFKISSST-GEIWVESSNGLDFEETPRLRLVVKAETVSSTSFMAFNLVLQDVNDNLPRFQLQNYVAFMKEAQGYEMPIIQVVAEDVDQGQNGQVTYSIQSSSMSGL---FKIDPVTGSITTT---AIMDREIFTQTKLVVTATDRGSPRLAGLATLTVIIIDQNDNSPTIPL---PQEIRIPENTLIGTEITL-VTGNDVDSSPALSYSLLLDPT---ALGKFGIHRYTGGVSITGPLDFEEKTWYTVTVQATDS---QHQTEANITIVVEDINDNAPLFTHDLYQISLPEHTPPGSAVITVTATDRDSGENGRVNYRVMSSTQEGFYIDPSNGTLFINHRAEFDPERPSVNIVI---EASDGGSPALSSLTTVQVHISDINDNAPVFHQSEYRAMVSEDTFPGSTLLIFEAFDNDLSRENCGFDFAIANGNEGNVFQIE-----SSVRFLEGRGFQTV---GTLLLAEGLDFETKSLYNLTVVVSDRGVPQRSSSVAALITIGDVNDNPPVFS-----RPEYTVALSEGAVSGTEIIR-LTATDPDSTPNAEVQYTISS---GDEMNLFSIDQWTGALRLQRALDREHQSTHVVIIQATDGQGYFALVPVIVDVKDVNDNH 2676 HSP 11 Score: 109.768 bits (273), Expect = 1.092e-23 Identity = 131/496 (26.41%), Postives = 209/496 (42.14%), Query Frame = 2
Query: 947 NDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCELQTESKID--FQLLKKKEN---LY-SLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKG---KAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVI-----PEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETL---QSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQ---IELTIIASDSATKP 2365
+DLD+ +T GI I +RRL +R Y+F V + V ITV DIN++ P +++ E+T+ G ++ +D D + ++ E + F+L K+ LY L D E S I+ D GSP + ++ V +TD+N+++P F Q Y + E+ + +LQ+ A D D + Y ++ + + +F ID SG I T N LD E+ A D P + + + D NDN P +I + E + + R++ TD D G + V L + K +K+ I + Q LDRE +SY L V D G P+ ++ T++V D NDN P + + I ++ V+ V A D D G NG ++Y + K FS+D +G I LDF+ +T+IA+D P
Sbjct: 73 SDLDIDETTGI------ITTKRRLDREERDHYSFIAVTMTG-------ITIEVSITVNDINDHAPEFP--KKKALLKIPEHTVVGTRFSLDPATDADKDQLTTQGYAIK-EGNVGHMFKLESKRSANKVLYLDLVVSGLLDREKRSSYSLVIEAFDGGSPRRVGFMTLEVTVTDINDHAPVFNQSRYHAIISESLPQGSSILQVFAADEDEGDNGLVLYEINRRQSDPERYFVIDLKSGVI-TLNRPLDYELKRVHELVVQARDNASQPEVTNAFVTIHVRDFNDNQPTMTIIFLSEDGSPRISEGAQPGQYVARISVTDPDYGEYANVNVSL------EGGDGKFALTTKDSIIYLIYVDQVLDREERDSYDLRVMATDSGTPPLRAESSFTIQVTDVNDNPPLF---DQQAYRQTIPEVVYPGSFVLQVTARDKDQGPNGDVRYSLLKGK-----KWFSIDPITGIITTATALDFESEPAPSVTVIATDGGRPP 537
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 239.965 bits (611), Expect = 4.008e-65 Identity = 218/730 (29.86%), Postives = 346/730 (47.40%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYAL-----------PDKLKFSSLKFNVDSQFLQINDN-GDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVI----AILSTNERVEVRE-NTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIIN-KNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
++EE + N IGNI L L + + DS +++ N G++ T RID E LC S+ + C + +V+V ND+ + + + + D NDN P+F + I++ E+ +N ++ SA D D + N + Y+L + + F LD K+PQ L ++ LD E + Y + +K D S + L + V D NDNKP+F +N +V I EN+ G+ VV + A D D G + Y + F +NS SG I ++R L + ++ V+A D ++P + V + +T D+N+ P I I N V + E + + + I VSD D +N KV C + E + F L +N Y L + D+E + + I +DSG P + V V + D N+ P F Q + E+++ EN + + L+ATD D A I Y L +FF +D +G + T + V DRE + +F A D P A +IVT+ DENDN P F +F V EN+ +G +T TD+D G N+ + +L + + FS G I++ S DRE SYT +V D G+ P +++ VT+ V+D NDN P + P P N + + + + +V V A D+D G N +KY I + + + +F +D +G I L
Sbjct: 30 IREELQENVLIGNIPKDLNISHTSAATGASANLVYRLVSKAGDSPLVRVLGNTGEIFTTSNRIDREKLCPGSSFEDAE--CSFEIEVVVLP-NDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPD-TGPNSVHKYELINGQSAFGLDIVETPEGEKWPQ--LIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGS-SSPARATVIINVT--DVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFI--EKDVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPNA-SFFDLDRKTG-VLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSILND--NENFILDPFS----GVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYP-PSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVS---GNNKGLFRIDPVTGNITL 736 HSP 2 Score: 120.168 bits (300), Expect = 4.210e-27 Identity = 127/455 (27.91%), Postives = 204/455 (44.84%), Query Frame = 2
Query: 1097 VPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCEL---QTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRY----SLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDN----------APIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEI---RLVKELDFDQIELTIIASDSATKPKMVMLKLII 2392
+ ++I V+D N+ P+ N + + ENTL + I +D D G NS EL Q+ +D + E L ++ D E IK D GSP KS+ + V +TD+N+ P F++ EV + EN+ T V+QL ATD D A I Y + K F ++ SG I + LDRE + A D P AT +I+ + D NDN +PI G + F +++ I+T+ I +T +D D N +V + K + ++ ++ + +ET LD E + Y ++ D GK + + V V++ DENDN P + P E + ++ + T+ A D D+G+N I Y++ PN+ F LD +G + R+ D D+ T+ A D+ T P +I+
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVIN--ISIPENTLINSRFAIPSATDPDTGPNSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQR-PLDREETAIHKLSVLASDGSSSPARAT--VIINVTDVNDNPPNIDLRYIISPINGTV--FLSEKDPINTK-IALITVSDKDTDINGKVICFIEKDVPF--HLKAVY--DNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQP---VIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQL---GPNAS--FFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIV 559
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 239.58 bits (610), Expect = 1.507e-64 Identity = 218/730 (29.86%), Postives = 346/730 (47.40%), Query Frame = 2
Query: 203 VKEEFKPNQFIGNIKYAL-----------PDKLKFSSLKFNVDSQFLQINDN-GDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDT------SKFPQISLRLKSELDYETRKQYRLTLKACDRDS---CTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVI----AILSTNERVEVRE-NTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIP-EFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIIN-KNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRL 2299
++EE + N IGNI L L + + DS +++ N G++ T RID E LC S+ + C + +V+V ND+ + + + + D NDN P+F + I++ E+ +N ++ SA D D + N + Y+L + + F LD K+PQ L ++ LD E + Y + +K D S + L + V D NDNKP+F +N +V I EN+ G+ VV + A D D G + Y + F +NS SG I ++R L + ++ V+A D ++P + V + +T D+N+ P I I N V + E + + + I VSD D +N KV C + E + F L +N Y L + D+E + + I +DSG P + V V + D N+ P F Q + E+++ EN + + L+ATD D A I Y L +FF +D +G + T + V DRE + +F A D P A +IVT+ DENDN P F +F V EN+ +G +T TD+D G N+ + +L + + FS G I++ S DRE SYT +V D G+ P +++ VT+ V+D NDN P + P P N + + + + +V V A D+D G N +KY I + + + +F +D +G I L
Sbjct: 30 IREELQENVLIGNIPKDLNISHTSAATGASANLVYRLVSKAGDSPLVRVLGNTGEIFTTSNRIDREKLCPGSSFEDAE--CSFEIEVVVLP-NDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPD-TGPNSVHKYELINGQSAFGLDIVETPEGEKWPQ--LIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGS-SSPARATVIINVT--DVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFI--EKDVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPNA-SFFDLDRKTG-VLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSILND--NENFILDPFS----GVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYP-PSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVS---GNNKGLFRIDPVTGNITL 736 HSP 2 Score: 120.939 bits (302), Expect = 2.644e-27 Identity = 127/455 (27.91%), Postives = 204/455 (44.84%), Query Frame = 2
Query: 1097 VPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITI-KVSDNDIGMNSKVNCEL---QTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGA--ASIRY----SLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDN----------APIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEI---RLVKELDFDQIELTIIASDSATKPKMVMLKLII 2392
+ ++I V+D N+ P+ N + + ENTL + I +D D G NS EL Q+ +D + E L ++ D E IK D GSP KS+ + V +TD+N+ P F++ EV + EN+ T V+QL ATD D A I Y + K F ++ SG I + LDRE + A D P AT +I+ + D NDN +PI G + F +++ I+T+ I +T +D D N +V + K + ++ ++ + +ET LD E + Y ++ D GK + + V V++ DENDN P + P E + ++ + T+ A D D+G+N I Y++ PN+ F LD +G + R+ D D+ T+ A D+ T P +I+
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVIN--ISIPENTLINSRFAIPSATDPDTGPNSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQR-PLDREETAIHKLSVLASDGSSSPARAT--VIINVTDVNDNPPNIDLRYIISPINGTV--FLSEKDPINTK-IALITVSDKDTDINGKVICFIEKDVPF--HLKAVY--DNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQP---VIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQL---GPNAS--FFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIV 559
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000002712.1 (SMESG000002712.1) HSP 1 Score: 2005.72 bits (5195), Expect = 0.000e+0 Identity = 1008/1010 (99.80%), Postives = 1010/1010 (100.00%), Query Frame = 2
Query: 125 MMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHXXXXXXXXXXXXXXXXXXTGFXXXXXXXXXXXXRKRPIGTGIKYSCPNALDLGKTNMAEWTFQDNSIYKQKPGIHYQLNDYQLPTQNVASSRTSYEPIDAEESGDSGKGPSEDIRNAPYLDQNQIFARNYANMQWKIPSPIPSTACNGRQLYMLPDRSMNLHNSNYGSPYPSLVVPKPNCETVNFNNPNPVNEADIHNLEFLSFNPYNANEFSLPRSPDYYQTSNSQSQIYETPDCFNSELDISHIQQSNI 3154
MMNIFLILWIFANFEFR+NCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHSRVASSPSVSVIIILISVTGFISIVLVVSIICVRKRPIGTGIKYSCPNALDLGKTNMAEWTFQDNSIYKQKPGIHYQLNDYQLPTQNVASSRTSYEPIDAEESGDSGKGPSEDIRNAPYLDQNQIFARNYANMQWKIPSPIPSTACNGRQLYMLPDRSMNLHNSNYGSPYPSLVVPKPNCETVNFNNPNPVNEA+IHNLEFLSFNPYNANEFSLPRSPDYYQTSNSQSQIYETPDCFNSELDISHIQQSNI
Sbjct: 1 MMNIFLILWIFANFEFRINCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHSRVASSPSVSVIIILISVTGFISIVLVVSIICVRKRPIGTGIKYSCPNALDLGKTNMAEWTFQDNSIYKQKPGIHYQLNDYQLPTQNVASSRTSYEPIDAEESGDSGKGPSEDIRNAPYLDQNQIFARNYANMQWKIPSPIPSTACNGRQLYMLPDRSMNLHNSNYGSPYPSLVVPKPNCETVNFNNPNPVNEAEIHNLEFLSFNPYNANEFSLPRSPDYYQTSNSQSQIYETPDCFNSELDISHIQQSNI 1010
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000002712.1 (SMESG000002712.1) HSP 1 Score: 2003.41 bits (5189), Expect = 0.000e+0 Identity = 1007/1009 (99.80%), Postives = 1009/1009 (100.00%), Query Frame = 2
Query: 128 MNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHXXXXXXXXXXXXXXXXXXTGFXXXXXXXXXXXXRKRPIGTGIKYSCPNALDLGKTNMAEWTFQDNSIYKQKPGIHYQLNDYQLPTQNVASSRTSYEPIDAEESGDSGKGPSEDIRNAPYLDQNQIFARNYANMQWKIPSPIPSTACNGRQLYMLPDRSMNLHNSNYGSPYPSLVVPKPNCETVNFNNPNPVNEADIHNLEFLSFNPYNANEFSLPRSPDYYQTSNSQSQIYETPDCFNSELDISHIQQSNI 3154
MNIFLILWIFANFEFR+NCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHSRVASSPSVSVIIILISVTGFISIVLVVSIICVRKRPIGTGIKYSCPNALDLGKTNMAEWTFQDNSIYKQKPGIHYQLNDYQLPTQNVASSRTSYEPIDAEESGDSGKGPSEDIRNAPYLDQNQIFARNYANMQWKIPSPIPSTACNGRQLYMLPDRSMNLHNSNYGSPYPSLVVPKPNCETVNFNNPNPVNEA+IHNLEFLSFNPYNANEFSLPRSPDYYQTSNSQSQIYETPDCFNSELDISHIQQSNI
Sbjct: 1 MNIFLILWIFANFEFRINCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGVIPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTLARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHSRVASSPSVSVIIILISVTGFISIVLVVSIICVRKRPIGTGIKYSCPNALDLGKTNMAEWTFQDNSIYKQKPGIHYQLNDYQLPTQNVASSRTSYEPIDAEESGDSGKGPSEDIRNAPYLDQNQIFARNYANMQWKIPSPIPSTACNGRQLYMLPDRSMNLHNSNYGSPYPSLVVPKPNCETVNFNNPNPVNEAEIHNLEFLSFNPYNANEFSLPRSPDYYQTSNSQSQIYETPDCFNSELDISHIQQSNI 1009
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000079318.1 (SMESG000079318.1) HSP 1 Score: 514.612 bits (1324), Expect = 2.075e-164 Identity = 342/1003 (34.10%), Postives = 555/1003 (55.33%), Query Frame = 2
Query: 194 NLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDR-NDFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRDSCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQ----LIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIFGV-IPEFTVKENMISTRLIGRLTATDADKGNNSQVEFVLLKTL--ARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGK---YPMATSTNVTVKVLDENDNKPQWMNPNPINPEYNITRIINKNELVMTVQAFDTDAGENGRIK------YRIHNPKPNSKQ---PVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHXXXXXXXXXXXXXXXXXXTGFXXXXXXXXXXXXRKRPIGTGIKYSCPNALDLGKTN-MAEWTF--QDNSIYKQKPG--------IHYQ-----LNDYQLPTQNVASSRTSYEPIDAEESGDSGKGPSEDIRN---APYLDQNQIFARNYANMQWKIPSPIPSTAC-NGRQLYMLPDRSMNLHNSNYGSPYPSLVVPKPNCETVNFNNPNPVNEADIHNLEFLSFNPYNANEFSLPRSPDYYQTSNS 3079
++ + EE PN IG+I A+P L+ +SL+F +S F + + G + ++K IDLETLC +CCG+ +C ++ +L+N++ + + S+ + +QI D ND+ P+F T E I + E + S+SL SA D+D S++ RI++YKL++ +N F LD S+ P I L++ +LD+E +KQY LKACD D+CT + LII ++DENDN+PIF Y ++I E+ GS++ V A D+DSG G + Y+I D D+ TF + + SG I+L+++L+ R Y F +VA+DSD NP++ V I VED+N++ P I I++ ++++E +P LI T+++ D D G N V C L + F+L + +++YSL SVR FD E Q A + C D G P + + + + ITD+NE+ P FK L+ V EN+ TKV+ + A D+D +A ++Y +D G +F+ID SG I+ N ++DRE + +I F D+ +P TA+ ++ +T+ D NDN+P+F +P+F++ EN ++L+G++ ATDAD+ N+ + F L + Q F+V G IETL LDRE + Y LE+ D K P+ + N+T++VLDEND P W +P+ N NIT + + ++ +QA D D G NG+++ YR + + Q F ++ +G + + + L + L ASD K KL+IN + + ++++I ++I+VT IS+ L+V+IICVR++P KY P + L K + +W D S+ G H +ND +P + A + +EPID +SGDSGKGPSE+ N P QN R ++ PIP++ +G Y+LP+ + + + SP+P+ P+ V P+N ADI ++ + S+N + + P S + T+++
Sbjct: 21 SIQMHEEIPPNSEIGSILSAIPHNLRSTSLEFITESDFFIVTEEGKILVRKLIDLETLCSQYKLCCGEPVCILKANILLNNKEKEVVSSVEIQVQILDKNDHNPIFETPETKIVISEFSQIGISISLTSATDKDHSSQYRIQNYKLDEPTNSFILDISQLPSIFLKVSKKLDFEEKKQYHAKLKACDEDNCTTQNLIIHIKDENDNQPIFETETYNLTIKEDVQIGSIIGQVKANDRDSGLFGTIKYSIRTDFDTDIQSTFYVETLSGRIKLKKKLSTFTRSRYPFRIVARDSDPINPKQSLCSVTILVEDVNDHKPEIRIIADLSSLKIQEE-IPSKLITTLQIVDQDKGPNGIVYCHLDPVCEGSFELQNRSKDIYSLRSVRKFDHEVEQKIDAIVICKDQGEPSLESRKIIPIIITDLNEFRPTFKDKSQYLLGHV--WENSEFGTKVMTVKAQDQDKSAVLKYQIDNYGAEYFEIDQNSGLIRCTNNLIDRERVSSISFTVHVMDSDTEPKTASVEVKITVLDANDNSPLFSTNLPQFSIIENTGPSQLVGQINATDADQDENALISFSLRNSWNGNTMQRHDNYFNVLPTGHIETLLKLDREICDLYILEIMASDSAKSPQIPLTSIVNITLRVLDENDESPTWTHPD--NNILNITDTMRPGDHLLQLQATDRDVGANGKVRFEIIKQYRKEDGSSSFNQGSSQYFIVNSSTGALWISQMLHSGTVILLFRASDYGQPAKYSDHKLVINIFGDESGNLNMTIIAVMITVTAVISLFLIVAIICVRRKP----PKYHSPTSSILTKEQPVPDWIGLNSDESLLAYPSGNKSPYITNSHRASFIPPMNDGTIPMRTYAPNCAQFEPIDG-DSGDSGKGPSEEGSNPHHMPQEGQNYYTIRQPVRGPFRPCVPIPASPSRSGCYCYVLPEET--IIQPGHPSPFPTFSQGDPSMSPV-----TPMN-ADISSIGYSSYNSLSLPRYHFPNSNSKFNTNST 1005 HSP 2 Score: 81.6481 bits (200), Expect = 2.428e-15 Identity = 123/499 (24.65%), Postives = 220/499 (44.09%), Query Frame = 2
Query: 188 TANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQF-LQINDNGDV-TLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRNDFIDSLTVNLQINDLNDNTPLFSTIE--QTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD--SCTDKELI-IDVQDENDNKPIFT-KNFYKVS-ILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRK---LYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTN-ERVEVRENTLPGNLI-TIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYS------LASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVL---VHITDMNEYSPEFKQLIYEV-SLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKI 1612
T NLT+KE+ + IG +K D F ++K+++ + F I V TL RI L+ F + +N + +V + + D+ND+ P I ++ ++E +P +L+ D+D + + FEL SLR + D+E ++ + D+ S +++I I + D N+ +P F K+ Y + + EN++ G+ V+TV A D+D ++ Y ID + F I+ NSG IR L +R +T HV+ D++ P+ V V+ITV D N+ P + STN + + ENT P L+ I +D D N+ ++ L+ + + +++ +N ++ + ++ D E + I +DS P+ S++ + + D N+ SP + + ++ + +LQL ATDRD A+ GK F+I
Sbjct: 234 TYNLTIKEDVQIGSIIGQVKANDRDSGLFGTIKYSIRTDFDTDIQSTFYVETLSGRIKLKKKLSTFTRSRYPFRIVARDSDPINPKQSL---CSVTILVEDVNDHKPEIRIIADLSSLKIQEEIPSKLITTLQ-IVDQDKGPNGIVYCHLDPVCEGSFELQNRSKDIYSLRSVRKFDHEVEQKIDAIVICKDQGEPSLESRKIIPIIITDLNEFRPTFKDKSQYLLGHVWENSEFGTKVMTVKAQDQDKS--AVLKYQIDNYG----AEYFEIDQNSGLIRCTNNLIDRERVSSISFTVHVMDSDTE---PKTASVEVKITVLDANDNSP---LFSTNLPQFSIIENTGPSQLVGQINATDADQDENALISFSLR--NSWNGNTMQRHDNYFNVLPTGHIETLLKLDREICDLYILEIMASDSAKSPQIPLTSIVNITLRVLDENDESPTWTHPDNNILNITDTMRPGDHLLQLQATDRDVGAN--------GKVRFEI 706
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000033639.1 (SMESG000033639.1) HSP 1 Score: 453.751 bits (1166), Expect = 1.074e-141 Identity = 285/802 (35.54%), Postives = 461/802 (57.48%), Query Frame = 2
Query: 137 FLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRN-DFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD-SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMIS-TRLIGRLTATDADKGN-NSQVEFVLLKTL--ARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINP---EYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLIINNHXXXXXXXXXXXXXXXXXXTGFXXXXXXXXXXXXRKRP 2512
F I+++F + +C T + EE + IGNI + P F+ + + S FL+++D GD+ L RIDLET+C +CC + C ++T ++ D++ D +S+ +++ ++D NDN P F +QT+ + E+ P+ + + L+ A D D ++ NR+ Y ++ + F LD S+ P I L +K LDYE + QY TL+ACD + C + L I V D+NDN P F++ Y++ ILEN G ++ V A DKDS ++Y +D ++ TF I N+G I+L+++L+A R+ Y F V A D K + I V+D+N+ P I LS N ++E+ E P L T++V+D+DIG+N+ V+C+L + DF+L +YSL+S+RSFD+E+ + A I+C D GSP +S+ VH+ D+NE++P F++ ++ L EN +LQ++A+DRDG+A ++YS + +F ID +G IK+ LDRE++E I N DA +P T +I+ + DENDN P F + F + EN+ S +++ GR+ ATD DK N++V F L T ++ + IF V++ G I T++ LDRE +YT+E+ D G ++ N T+ V D+NDN P W+ P + NIT L++ +QA D D GEN + Y + N+ + +F L++ +GE+R+ + L Q +L + ASD+ P+ L I + ++ ++S+II+LI +TGFISI L+++IICVR+RP
Sbjct: 5 FCIIFLFY-LCHQGSCQTVTFKIMEESPIDMVIGNIVHLHP---SFNKASYFIKSPFLKLSDKGDLMLSSRIDLETICAQHEMCCEEVECILKTTIMAKDKSSDQSESINIHVSVSDKNDNWPKFVKPKQTVNVAENEPIGFYLYLDRALDADATSANRVHQYIFKEPTGTFNLDQSRLPSIGLIVKKPLDYEVKSQYFATLEACDTNKQCNTQALEIHVLDQNDNYPSFSQQEYQIEILENFPVGQQIIAVEAIDKDSDLFNKIIYGFHELSDNNIRNTFIITENTGSIKLQKKLSAKVRQKYKFKVFAADKMAMAFHKAVANIFIKVKDLNDNSPKITSLSGNSKIEINETDPPRELFTLQVTDDDIGVNANVSCQLLQQYINDFRLDAVGNEIYSLSSIRSFDYENEREIKAEIECYDHGSPRNVAHKSLNVHVKDINEFAPRFEKDFQKLKLLENREQGHNILQVSASDRDGSAVLKYSFTGEPNDYFTIDPHTGQIKSGIRRLDREMVERIEINIIVTDAIENPKTGQCTVIIEVLDENDNPPTFIDISGVFNISENLSSYSKVRGRIAATDKDKDEINNKVLFQLQHTFDSQNRRISEPIFKVTESGEILTVKKLDREINHNYTVEIRAFDTGLPMLSAHKNFTIYVEDQNDNDPDWVTPLSSHGGIHTVNITANSPPGYLIIKLQATDPDYGENSNVTYSVM----NNNKLLFILNQVTGELRVARLLPIGQFQLFLRASDNGRPPRHNETSLFIFINGDEVATLNMSIIIVLIGITGFISIFLIIAIICVRRRP 798
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000033639.1 (SMESG000033639.1) HSP 1 Score: 446.047 bits (1146), Expect = 3.866e-139 Identity = 261/738 (35.37%), Postives = 419/738 (56.78%), Query Frame = 2
Query: 209 EEFKPNQFIGNIKYALPDKLKFSSLKFNVDSQFLQINDNGDVTLKKRIDLETLCQNSNICCGQFLCFIQTKVLVNDRN-DFIDSLTVNLQINDLNDNTPLFSTIEQTITLRESLPVNYSMSLESAFDRDFSAENRIESYKLEDSSNKFELDTSKFPQISLRLKSELDYETRKQYRLTLKACDRD-SCTDKELIIDVQDENDNKPIFTKNFYKVSILENTDTGSLVVTVNAYDKDSGDLGLVMYNIDAPNDLDLIQTFGINSNSGEIRLERRLAANQRKLYTFHVVAKDSDFNNPQKEKVPVEITVEDINNYYPVIAILSTNERVEVRENTLPGNLITIKVSDNDIGMNSKVNCELQTESKIDFQLLKKKENLYSLASVRSFDFESGQVKSASIKCTDSGSPPKSTDRSVLVHITDMNEYSPEFKQLIYEVSLRENTATNTKVLQLNATDRDGAASIRYSLDEKGKAFFKIDHMSGWIKTKNVVLDREVIETIVFNAFAHDAYVDPFTATTKIIVTIEDENDNAPIF-GVIPEFTVKENMIS-TRLIGRLTATDADKGN-NSQVEFVLLKTL--ARKQEVQKIFSVSKEGFIETLQSLDRETFESYTLEVGVRDKGKYPMATSTNVTVKVLDENDNKPQWMNPNPINP---EYNITRIINKNELVMTVQAFDTDAGENGRIKYRIHNPKPNSKQPVFSLDEDSGEIRLVKELDFDQIELTIIASDSATKPKMVMLKLII 2392
EE + IGNI + P F+ + + S FL+++D GD+ L RIDLET+C +CC + C ++T ++ D++ D +S+ +++ ++D NDN P F +QT+ + E+ P+ + + L+ A D D ++ NR+ Y ++ + F LD S+ P I L +K LDYE + QY TL+ACD + C + L I V D+NDN P F++ Y++ ILEN G ++ V A DKDS ++Y +D ++ TF I N+G I+L+++L+A R+ Y F V A D K + I V+D+N+ P I LS N ++E+ E P L T++V+D+DIG+N+ V+C+L + DF+L +YSL+S+RSFD+E+ + A I+C D GSP +S+ VH+ D+NE++P F++ ++ L EN +LQ++A+DRDG+A ++YS + +F ID +G IK+ LDRE++E I N DA +P T +I+ + DENDN P F + F + EN+ S +++ GR+ ATD DK N++V F L T ++ + IF V++ G I T++ LDRE +YT+E+ D G ++ N T+ V D+NDN P W+ P + NIT L++ +QA D D GEN + Y + N+ + +F L++ +GE+R+ + L Q +L + ASD+ P+ L I
Sbjct: 2 EESPIDMVIGNIVHLHP---SFNKASYFIKSPFLKLSDKGDLMLSSRIDLETICAQHEMCCEEVECILKTTIMAKDKSSDQSESINIHVSVSDKNDNWPKFVKPKQTVNVAENEPIGFYLYLDRALDADATSANRVHQYIFKEPTGTFNLDQSRLPSIGLIVKKPLDYEVKSQYFATLEACDTNKQCNTQALEIHVLDQNDNYPSFSQQEYQIEILENFPVGQQIIAVEAIDKDSDLFNKIIYGFHELSDNNIRNTFIITENTGSIKLQKKLSAKVRQKYKFKVFAADKMAMAFHKAVANIFIKVKDLNDNSPKITSLSGNSKIEINETDPPRELFTLQVTDDDIGVNANVSCQLLQQYINDFRLDAVGNEIYSLSSIRSFDYENEREIKAEIECYDHGSPRNVAHKSLNVHVKDINEFAPRFEKDFQKLKLLENREQGHNILQVSASDRDGSAVLKYSFTGEPNDYFTIDPHTGQIKSGIRRLDREMVERIEINIIVTDAIENPKTGQCTVIIEVLDENDNPPTFIDISGVFNISENLSSYSKVRGRIAATDKDKDEINNKVLFQLQHTFDSQNRRISEPIFKVTESGEILTVKKLDREINHNYTVEIRAFDTGLPMLSAHKNFTIYVEDQNDNDPDWVTPLSSHGGIHTVNITANSPPGYLIIKLQATDPDYGENSNVTYSVM----NNNKLLFILNQVTGELRVARLLPIGQFQLFLRASDNGRPPRHNETSLFI 732 The following BLAST results are available for this feature:
BLAST of Protocadherin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30029104 ID=SMED30029104|Name=Protocadherin|organism=Schmidtea mediterranea sexual|type=transcript|length=3180bpback to top protein sequence of SMED30029104-orf-1 >SMED30029104-orf-1 ID=SMED30029104-orf-1|Name=SMED30029104-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1011bp MMNIFLILWIFANFEFRVNCWTANLTVKEEFKPNQFIGNIKYALPDKLKFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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