Transient receptor potential cation channel subfamily M member 2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30029075 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 321.242 bits (822), Expect = 2.014e-90 Identity = 305/1155 (26.41%), Postives = 530/1155 (45.89%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEE-----SSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICK------NSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I TT +EE E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ P+ + I I YI L E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C+ + + + FI + +E + FE+QC+E Y
Sbjct: 139 FGTIEFQG----GGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDIPLRRGRKTTK-------KREEEVDIDLDDPEINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMSQAQEI----HLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER---WPST-----QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD---DELKKVHDFEEQCIEEY 1202
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 319.701 bits (818), Expect = 4.396e-89 Identity = 307/1156 (26.56%), Postives = 532/1156 (46.02%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEE-----SSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICK------NSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I TT +EE E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C+ + + + FI + +E + FE+QC+E Y
Sbjct: 139 FGTIEFQG----GGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDIPLRRGRKTTK-------KREEEVDIDLDDPEINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMSQAQEI----HLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD---DELKKVHDFEEQCIEEY 1202
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 315.464 bits (807), Expect = 7.308e-88 Identity = 306/1145 (26.72%), Postives = 531/1145 (46.38%), Query Frame = 1
Query: 202 YVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQC------------LFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICK------NSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YVRV D L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I P+ T +++ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V D+ + + C C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C+ + + + FI + +E + FE+QC+E Y
Sbjct: 2 YVRVSFDTK--PDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PLRRGRKTTKKREEEVDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMSQAQEI----HLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDRKQVYDSHTPKSAPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD---DELKKVHDFEEQCIEEY 1061
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 314.694 bits (805), Expect = 1.312e-87 Identity = 307/1145 (26.81%), Postives = 529/1145 (46.20%), Query Frame = 1
Query: 202 YVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANA----HLHTAVN---------FIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICK------NSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YVRV D L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY + HL V FKG + + SL IG +I L + Y + + K PK + +++ E I P+ T +++ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C+ + + + FI + +E + FE+QC+E Y
Sbjct: 2 YVRVSFDTK--PDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PLRRGRKTTKKREEEVDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMSQAQEI----HLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD---DELKKVHDFEEQCIEEY 1061
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 314.694 bits (805), Expect = 1.312e-87 Identity = 307/1145 (26.81%), Postives = 529/1145 (46.20%), Query Frame = 1
Query: 202 YVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANA----HLHTAVN---------FIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICK------NSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YVRV D L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY + HL V FKG + + SL IG +I L + Y + + K PK + +++ E I P+ T +++ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C+ + + + FI + +E + FE+QC+E Y
Sbjct: 2 YVRVSFDTK--PDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PLRRGRKTTKKREEEVDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMSQAQEI----HLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD---DELKKVHDFEEQCIEEY 1061
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Celegans
Match: gtl-2 (Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:Q20766]) HSP 1 Score: 286.96 bits (733), Expect = 3.200e-79 Identity = 301/1133 (26.57%), Postives = 521/1133 (45.98%), Query Frame = 1
Query: 199 KYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSK-KQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVS----KEADCSVVQLIVEGGKNTIQTGAE--ALKSNIPVVVMKGSKRAADVICDVVE--SSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFK-GTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKA-----GAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIP----NFVNIFQILINVP----FGY-----LTSRIFI--FPYNLLGKRQTQAVQTNNS---EPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFF------MGGQVKNFISK-FNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNI-NITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFK-LNICKNSNNGRLSVDAFIANLIHEEDLE-CSGFEQQCMET 3453
+YVR+ D + ++ LM VWG + P+L+I+++GG N L F++G++ +++ WI+T G ++GV + V +A + I ++ + +GI WG KE+L Q E Y + V L+ H F+L D+G+ +FG ++ R E ++ VV ++EGG ++I + +K +IP +V GS RAAD+I +S F + KL K TD+E+ F+K EC + + L + + + + S ++ Q L + +L L +++NR D+A+ +F N RK ++ L M AL ++ FV+ L G+++++FL+ + L +LY + N+ H+ N++ ++D ++ MIG+++ +L N F Q+Y + S +K +I+ S F+ +++ E + + + IN +EE Y DL +WA+LT R MA+ W G+D + L+A + + K A + + +N ++ +E+ AI +L + YR D RT LL LP+WG +CL +A FL H CQ L +W G + + V + LI P Y T+R+ P L R++ T+N G E + E + + I + +N+ + + FKR L+KF + R FY++PITKF I++L FLT + LL+E +L P+ Y E+ +I+ ++ + I + + +VK F +K +N W S+ +F +G F + + R++ + R L S S +FY++ E+ V +GP + M ++M+ + + + L+ L A+G +L PN+ + L+RNIFY PY+ L+G+V DT EG +C GY P +V FLL N+LLL+LLIA+F + E S +W F RY+ + E++ P LPPPF++F Y+F L + + R + I + E++++ FE+ C++T
Sbjct: 171 QYVRLSYDSEPL--DVMYLMEKVWGLEAPRLVITVHGGMSN-FELEERLGRLFRKGMLKAAQTTGAWIITSGLDSGVVRHVAKALDEAGISARMRSQIVTIGIAPWGVIKRKERLIRQNEH---VYYDVHSLSVNANVGILNDRHSYFLLADNGTVGRFGADLHLRQNLENHIATFGCNGRKVPVVCTLLEGGISSINAIHDYVTMKPDIPAIVCDGSGRAADIISFAARYINSDGTFAAEVGEKLRNLIKMVFPETDQEEM-FRK----ITEC--VIRDDLLRIFRYGQEEEEDVDFVILSTVLQKQNLPPDEQLALTLSWNRVDLAKSCLFSNG-RKWSSDV-LEKAMNDALYWDRVDFVECLLENGVSMKNFLSINRLENLYNMDDINS-AHSVRNWMENFDSMDPHTYLTIPMIGQVVEKLMGNAF-QLYYTSRSFKGKYDRYK--RINQSSYFHRKR-KIVQKELFKKKSDDQ----------INDNEEEDFSFAYPF--------------NDLLIWAVLTSRHGMAECMWVHGEDAMAKCLLAIRLYKATAKIAEDEYLDVEEAKRLFDNAVKCRED----AIELLDQCYRADHDRTLRLLRMELPHWGNNNCLSLAVLANTKTFLAHPCCQILLAELWHGSLKVRSGSNVRVLTALICPPAILFMAYKPKHSKTARLLSEETPEQLPYPRESITSTTSNRYRYSKGPEEQKETLLEKGSYTKKVTIISSRKNSGVASVYGSASSMM---FKREPQLNKFER--------------FRAFYSSPITKFWSWCIAFLIFLTTQTCILLLE---TSLKPSKY----EWITFIYTVTLSVEHIRKLMTSEGSRINEKVKVFYAKWYNIWTSAALLFFLVG--YGFRLVPMYRHS-------WGRVLLSFSNVLFYMKIFEYLSVHPLLGPYIQMAAKMVWSMCYICVLLLVPLMAFGVNRQALTEPNVKDWHWLLVRNIFYKPYFMLYGEVYAGEIDTCGDEGIRCFPGYFIPPLLMV-----IFLLVANILLLNLLIAIFNNIYNDSIEKSKEIWLFQRYQQLMEYHDSPFLPPPFSIFAHVYHFIDYLYNLRRPDTKRFRSEHSIKLSVTEDEMKRIQDFEEDCIDT 1217
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Celegans
Match: gtl-1 (GTL-1; Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:G5ECM4]) HSP 1 Score: 139.428 bits (350), Expect = 6.999e-33 Identity = 124/455 (27.25%), Postives = 209/455 (45.93%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLA--FKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPN--YDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVS----KEADCSVVQLIVEGGKNTIQTGAEALKS--NIPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYEC-YQIGKVHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMY 1470
YG I G + +Y R+ D + ++ LM VW K PKLII++NGG + + KLA F++G++ ++KS WI+T G + GV K + A D+ + K +GI +WG + + +D +TY ++ ++ + L+ H F+ D+G+ ++G EI R E ++ K + +V +++EGG TI+ + + + IPV+V GS RAAD++ ++ S D I+ +L + + QK + EC + +F + + + +LD I+ S +K Q L +L LA+ +NRAD+A IF N +L M AL ++ FV L G++++ FLT L LY +K + N + +DS L +GRL+ L NL+ Y
Sbjct: 196 YGNIVFEG----TAHHAQYARISFD--SDPRDIVHLMMKVWKLKPPKLIITINGG---LTKFDLQPKLARTFRKGIMKIAKSTDAWIITSGLDEGVVKHLDSALHDHGNHTSKNHVVAIGIASWGMLKQRSRFV--GKDSTVTYATNVFNNTRLKE----LNDNHSYFLFSDNGTVNRYGAEIIMRKRLEAYLAQGDKKRSAIPLVCVVLEGGAFTIKMVHDYVTTIPRIPVIVCDGSGRAADILAFAHQAVSQNGFLSDNIRNQLVNIVRR---IFGYDPKTAQKLIKQIVECSTNKSLMTIFRLGESSREDLDHVIM----SCLLKGQNLSPPEQLQLALAWNRADIARTEIFANGTEWT--TQDLHNAMIEALSNDRIDFVHLLLENGVSMQKFLTYGRLEHLYNTDKGPQNT-LRTNLL----VDSKHHIKLVEVGRLVENLMGNLYKSNY 621 HSP 2 Score: 94.3597 bits (233), Expect = 4.643e-19 Identity = 49/132 (37.12%), Postives = 75/132 (56.82%), Query Frame = 1
Query: 1711 YTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAG-AKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKI 2103
Y DL +WA+LT+R +MAK+ W G++ + ALVA+ + SL K A A GEI + ++ + +EF LA+ +L + + +T LL L WG E+CL +A N FL H CQ L+++W G +
Sbjct: 715 YPYSDLMIWAVLTKRQKMAKLMWTHGEEGMAKALVASRLYVSLAKTASLATGEIGMSQDFTEFSDEFSELAVEVLEYCTKHGRDQTLRLLTCELANWGDETCLSLAANNGHRKFLAHPCCQMLLSDLWQGGL 846 HSP 3 Score: 66.6254 bits (161), Expect = 1.267e-10 Identity = 83/329 (25.23%), Postives = 145/329 (44.07%), Query Frame = 1
Query: 2458 FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAY------------SRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQ------------------CLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKL 3339
FY APIT + + +++ FL + +Y LL++ I Y RK+ I + +L ++ FF Q +N + F + + IAY +R ++ + R L + ++ ++ +++ VQQ +GP + +++ M+ ++ + I L+A+G S+ YP + L+RNIF PY+ L+G+V DT E Q C+ GY P V F+L TNVLL+++++A F K +++ ++ F RY + E+ P LPPPF + FKL
Sbjct: 1073 FYKAPITTYWLWFFAFIWFLILLTYNLLVKTQRIASWSEWYVFAYIFVWTLEIGRKVVSTIMMDTSKPVLKQLRVFFF--QYRNGLLAFG--------------LLTYLIAYFIR--LSPTTKTLGRILIICNSVIWSLKLVDYLSVQQGLGPYINIVAEMIPTMIPLCVLVFITLYAFGLLRQSITYPYEDWHWILVRNIFLQPYFMLYGEVYAAEIDTCGDEIWQTHEDENIPISMLNVTHETCVPGYWIAP-----VGLTVFMLATNVLLMNVMVAGCTYIFEKHIQSTREIFLFERYGQVMEYESTPWLPPPFTIIYHVIWLFKL 1378
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 117.857 bits (294), Expect = 3.058e-26 Identity = 110/415 (26.51%), Postives = 197/415 (47.47%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLA--FKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKS--NIPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKD-FKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA 1341
+G ++ G G +P +YVRV+ D + L +VW P+LII+++GG N + KLA F++GL+ + + WI+T G +TGV K V A+ + + +++ +GI WG +E Q + T P Y G+ L+ H F+L D+G+ ++G E+ R E +S++ VV +++EGG TI++ + + + +PVVV GS RAAD++ ++ ++ + D I+ ++ + ++ L + + + + +F + + ++++D AI+ A G Q L +L LA+ +NR D+A +F + L M ALI ++ FV L QG+ ++ FLT S L +LY +K
Sbjct: 277 FGQVEFQG-----GPHPYKAQYVRVNFDTE--PAYIMSLFEHVWQISPPRLIITVHGGTSN---FDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVA-AALEGAQSAQRNKIVCIGIAPWGLLKKREDFIGQDK----TVPYYPSSSKGRFTG-LNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTEDGLLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNL--LTIFRLGEQGEHDVDHAILTALLKG----QNLSAADQLALALAWNRVDIARSDVF--AMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKG 667 HSP 2 Score: 90.1225 bits (222), Expect = 7.911e-18 Identity = 78/299 (26.09%), Postives = 140/299 (46.82%), Query Frame = 1
Query: 2458 FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYME-------------------GSQCLFGYCATPNAI---VQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEF 3273
FY+API+ F IS++ F+T F+Y LL++ PT IEY + + +F L ++ + M K F K + S WN + I + + + +R Y R + + ++ ++ +++ V +GP V M +M++++ + + + ++ L ++G S+ YP+ L+RNIF PY+ L+G+V DT E G C+ GY P + + +AN +LL+S+LIA+F F +E S ++W F RY+ + E+
Sbjct: 1201 FYSAPISTFWSWTISFILFITFFTYTLLVK---TPPRPTV----IEYILIAYVAAFGLEQVRKIIMS-DAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCF---GSVAYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIAN--------ILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEY 1480 HSP 3 Score: 84.3445 bits (207), Expect = 5.363e-16 Identity = 57/178 (32.02%), Postives = 86/178 (48.31%), Query Frame = 1
Query: 1711 YTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAK-GEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLG----KIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNN 2229
Y +L +WA+LT+R +MA W+ G++ + ALVA + SL +A E+EI +Y EEF L++ +L Y D +T LL L W E+CL +A +FL H CQ L ++W G + + + + LI PF + F LL + QT A N+
Sbjct: 850 YPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFIQMLE--FKTREELLNQPQTAAEHQND 1025
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 117.472 bits (293), Expect = 3.814e-26 Identity = 110/415 (26.51%), Postives = 197/415 (47.47%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLA--FKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKS--NIPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKD-FKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA 1341
+G ++ G G +P +YVRV+ D + L +VW P+LII+++GG N + KLA F++GL+ + + WI+T G +TGV K V A+ + + +++ +GI WG +E Q + T P Y G+ L+ H F+L D+G+ ++G E+ R E +S++ VV +++EGG TI++ + + + +PVVV GS RAAD++ ++ ++ + D I+ ++ + ++ L + + + + +F + + ++++D AI+ A G Q L +L LA+ +NR D+A +F + L M ALI ++ FV L QG+ ++ FLT S L +LY +K
Sbjct: 378 FGQVEFQG-----GPHPYKAQYVRVNFDTE--PAYIMSLFEHVWQISPPRLIITVHGGTSN---FDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVA-AALEGAQSAQRNKIVCIGIAPWGLLKKREDFIGQDK----TVPYYPSSSKGRFTG-LNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTEDGLLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNL--LTIFRLGEQGEHDVDHAILTALLKG----QNLSAADQLALALAWNRVDIARSDVF--AMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKG 768 HSP 2 Score: 90.5077 bits (223), Expect = 6.821e-18 Identity = 78/299 (26.09%), Postives = 140/299 (46.82%), Query Frame = 1
Query: 2458 FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYME-------------------GSQCLFGYCATPNAI---VQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEF 3273
FY+API+ F IS++ F+T F+Y LL++ PT IEY + + +F L ++ + M K F K + S WN + I + + + +R Y R + + ++ ++ +++ V +GP V M +M++++ + + + ++ L ++G S+ YP+ L+RNIF PY+ L+G+V DT E G C+ GY P + + +AN +LL+S+LIA+F F +E S ++W F RY+ + E+
Sbjct: 1302 FYSAPISTFWSWTISFILFITFFTYTLLVK---TPPRPTV----IEYILIAYVAAFGLEQVRKIIMS-DAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCF---GSVAYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIAN--------ILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEY 1581 HSP 3 Score: 84.3445 bits (207), Expect = 5.069e-16 Identity = 57/178 (32.02%), Postives = 86/178 (48.31%), Query Frame = 1
Query: 1711 YTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAK-GEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLG----KIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNN 2229
Y +L +WA+LT+R +MA W+ G++ + ALVA + SL +A E+EI +Y EEF L++ +L Y D +T LL L W E+CL +A +FL H CQ L ++W G + + + + LI PF + F LL + QT A N+
Sbjct: 951 YPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFIQMLE--FKTREELLNQPQTAAEHQND 1126
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 117.087 bits (292), Expect = 4.784e-26 Identity = 110/415 (26.51%), Postives = 197/415 (47.47%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLA--FKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKS--NIPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKD-FKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA 1341
+G ++ G G +P +YVRV+ D + L +VW P+LII+++GG N + KLA F++GL+ + + WI+T G +TGV K V A+ + + +++ +GI WG +E Q + T P Y G+ L+ H F+L D+G+ ++G E+ R E +S++ VV +++EGG TI++ + + + +PVVV GS RAAD++ ++ ++ + D I+ ++ + ++ L + + + + +F + + ++++D AI+ A G Q L +L LA+ +NR D+A +F + L M ALI ++ FV L QG+ ++ FLT S L +LY +K
Sbjct: 317 FGQVEFQG-----GPHPYKAQYVRVNFDTE--PAYIMSLFEHVWQISPPRLIITVHGGTSN---FDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVA-AALEGAQSAQRNKIVCIGIAPWGLLKKREDFIGQDK----TVPYYPSSSKGRFTG-LNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTEDGLLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNL--LTIFRLGEQGEHDVDHAILTALLKG----QNLSAADQLALALAWNRVDIARSDVF--AMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKG 707 HSP 2 Score: 90.5077 bits (223), Expect = 7.124e-18 Identity = 78/299 (26.09%), Postives = 140/299 (46.82%), Query Frame = 1
Query: 2458 FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYME-------------------GSQCLFGYCATPNAI---VQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEF 3273
FY+API+ F IS++ F+T F+Y LL++ PT IEY + + +F L ++ + M K F K + S WN + I + + + +R Y R + + ++ ++ +++ V +GP V M +M++++ + + + ++ L ++G S+ YP+ L+RNIF PY+ L+G+V DT E G C+ GY P + + +AN +LL+S+LIA+F F +E S ++W F RY+ + E+
Sbjct: 1241 FYSAPISTFWSWTISFILFITFFTYTLLVK---TPPRPTV----IEYILIAYVAAFGLEQVRKIIMS-DAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCF---GSVAYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIAN--------ILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEY 1520 HSP 3 Score: 84.3445 bits (207), Expect = 5.716e-16 Identity = 57/178 (32.02%), Postives = 86/178 (48.31%), Query Frame = 1
Query: 1711 YTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAK-GEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLG----KIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNN 2229
Y +L +WA+LT+R +MA W+ G++ + ALVA + SL +A E+EI +Y EEF L++ +L Y D +T LL L W E+CL +A +FL H CQ L ++W G + + + + LI PF + F LL + QT A N+
Sbjct: 890 YPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFIQMLE--FKTREELLNQPQTAAEHQND 1065
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339075) HSP 1 Score: 306.22 bits (783), Expect = 1.622e-86 Identity = 308/1154 (26.69%), Postives = 516/1154 (44.71%), Query Frame = 1
Query: 97 PSVESDC-SEFW---RHEKFQ----YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELY-KLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV--LGIGTWG-ATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK-------EADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEF-----EKEWNITTDEEKGNFQ--------KNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNE-ININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-----LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKG-EIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAV-QTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXED---FKRTEYLSKFRK-EQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR---NTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFI 3390
P +ES + W +H + Q YG I+ G G +P +YVR+ D + EL +L T W + PKL+I++ GG N L K ++GL+ +K+ WI TGG TGV+K VG+A + +++T V +GI WG N E L E P + + L+ H F+L D+G+ K+G E+ R + E+ +S + VV L++EGG NTI+ E + + +PVVV GS RAAD++ V + +SD + + + ++ +K + + D+ + +Q KNL+ + + + LD I+ A F K Q L +L LA+T+NR D+A IF V E N L M AL ++ FV L G++++ FLT L +LY + A+ L I KG I +L IG +IN+L + Y K+ +S + Y++Y + G + EM +P +L +WA+LT+R +MA + W G++ + +LV+ + ++ +A + EI Y +EFE+ +L +YR+D + LL L W +SCL +A L H Q L ++W+G + N F++++ + + +I + K + Q + QT + L D S+ Q +E ++ Y + + K D F+ LS++ + +QH+ L FYTAPITKF + I+Y+ FL MFS+ +L+++ + YS I YI+ L E + + + KF+ W +MWN D I+F I R NT++ IYC + +Y+R + V + +GP V M+ +M+K++++F+ + + L ++G ++LYPN T L++ + + PY+ L+G+V D G C T + + + + +LL N+LL++LLIA+F F +V S++VW F R+ ++ E+ +P+LPPPF FY+ K + K +S +F+
Sbjct: 51 PGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQG-----GAHPTKAQYVRLSFD---TRPELLVQLFTKEWNLELPKLLITVQGGKANF-DLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDA---LLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNRE-----VPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQE-------KPEGEAQELDQTILTALF----KSQHLSPPEQLSLALTWNRVDIARSEIF---VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYI-----YTLHDIGLVINKLMGGAYRSYYTRRKFRPIYA------KVMNSYANACRKSSTYQYQRY---------AGANSLSLVTGLLPFTSEMALFEFPF-----------NELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPF-----YIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLR---LKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYS--------IAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFRENTMDIGRVIYC-----VDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRKAKGEPGMSKFSFV 1121
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339079) HSP 1 Score: 309.686 bits (792), Expect = 4.170e-86 Identity = 317/1190 (26.64%), Postives = 534/1190 (44.87%), Query Frame = 1
Query: 97 PSVESDC-SEFW---RHEKFQ----YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELY-KLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV--LGIGTWG-ATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK-------EADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEF-----EKEWNITTDEEKGNFQ--------KNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNE-ININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-----LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKG-EIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAV-QTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXED---FKRTEYLSKFRK-EQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR---NTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLE-CSGFEQQCMETY-----LITNQLLD 3480
P +ES + W +H + Q YG I+ G G +P +YVR+ D + EL +L T W + PKL+I++ GG N L K ++GL+ +K+ WI TGG TGV+K VG+A + +++T V +GI WG N E L E P + + L+ H F+L D+G+ K+G E+ R + E+ +S + VV L++EGG NTI+ E + + +PVVV GS RAAD++ V + +SD + + + ++ +K + + D+ + +Q KNL+ + + + LD I+ A F K Q L +L LA+T+NR D+A IF V E N L M AL ++ FV L G++++ FLT L +LY + A+ L I KG I +L IG +IN+L + Y K+ +S + Y++Y + G + EM +P +L +WA+LT+R +MA + W G++ + +LV+ + ++ +A + EI Y +EFE+ +L +YR+D + LL L W +SCL +A L H Q L ++W+G + N F++++ + + +I + K + Q + QT + L D S+ Q +E ++ Y + + K D F+ LS++ + +QH+ L FYTAPITKF + I+Y+ FL MFS+ +L+++ + YS I YI+ L E + + + KF+ W +MWN D I+F I R NT++ IYC + +Y+R + V + +GP V M+ +M+K++++F+ + + L ++G ++LYPN T L++ + + PY+ L+G+V D G C T + + + + +LL N+LL++LLIA+F F +V S++VW F R+ ++ E+ +P+LPPPF FY+ K + + + + D + + ++DLE FE++C+E + +I NQ D
Sbjct: 58 PGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQG-----GAHPTKAQYVRLSFD---TRPELLVQLFTKEWNLELPKLLITVQGGKAN-FDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDA---LLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNRE-----VPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQE-------KPEGEAQELDQTILTALF----KSQHLSPPEQLSLALTWNRVDIARSEIF---VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYI-----YTLHDIGLVINKLMGGAYRSYYTRRKFRPIYA------KVMNSYANACRKSSTYQYQRY---------AGANSLSLVTGLLPFTSEMALFEFPF-----------NELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPF-----YIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLR---LKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYS--------IAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFRENTMDIGRVIYC-----VDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCV-RKAKGLEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTD 1163
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339076) HSP 1 Score: 309.686 bits (792), Expect = 4.835e-86 Identity = 317/1190 (26.64%), Postives = 534/1190 (44.87%), Query Frame = 1
Query: 97 PSVESDC-SEFW---RHEKFQ----YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELY-KLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV--LGIGTWG-ATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK-------EADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEF-----EKEWNITTDEEKGNFQ--------KNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNE-ININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-----LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKG-EIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAV-QTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXED---FKRTEYLSKFRK-EQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR---NTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLE-CSGFEQQCMETY-----LITNQLLD 3480
P +ES + W +H + Q YG I+ G G +P +YVR+ D + EL +L T W + PKL+I++ GG N L K ++GL+ +K+ WI TGG TGV+K VG+A + +++T V +GI WG N E L E P + + L+ H F+L D+G+ K+G E+ R + E+ +S + VV L++EGG NTI+ E + + +PVVV GS RAAD++ V + +SD + + + ++ +K + + D+ + +Q KNL+ + + + LD I+ A F K Q L +L LA+T+NR D+A IF V E N L M AL ++ FV L G++++ FLT L +LY + A+ L I KG I +L IG +IN+L + Y K+ +S + Y++Y + G + EM +P +L +WA+LT+R +MA + W G++ + +LV+ + ++ +A + EI Y +EFE+ +L +YR+D + LL L W +SCL +A L H Q L ++W+G + N F++++ + + +I + K + Q + QT + L D S+ Q +E ++ Y + + K D F+ LS++ + +QH+ L FYTAPITKF + I+Y+ FL MFS+ +L+++ + YS I YI+ L E + + + KF+ W +MWN D I+F I R NT++ IYC + +Y+R + V + +GP V M+ +M+K++++F+ + + L ++G ++LYPN T L++ + + PY+ L+G+V D G C T + + + + +LL N+LL++LLIA+F F +V S++VW F R+ ++ E+ +P+LPPPF FY+ K + + + + D + + ++DLE FE++C+E + +I NQ D
Sbjct: 51 PGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQG-----GAHPTKAQYVRLSFD---TRPELLVQLFTKEWNLELPKLLITVQGGKANF-DLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDA---LLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNRE-----VPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQE-------KPEGEAQELDQTILTALF----KSQHLSPPEQLSLALTWNRVDIARSEIF---VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYI-----YTLHDIGLVINKLMGGAYRSYYTRRKFRPIYA------KVMNSYANACRKSSTYQYQRY---------AGANSLSLVTGLLPFTSEMALFEFPF-----------NELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPF-----YIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLR---LKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYS--------IAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFRENTMDIGRVIYC-----VDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCV-RKAKGLEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTD 1156
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339074) HSP 1 Score: 309.301 bits (791), Expect = 5.703e-86 Identity = 317/1190 (26.64%), Postives = 534/1190 (44.87%), Query Frame = 1
Query: 97 PSVESDC-SEFW---RHEKFQ----YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELY-KLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV--LGIGTWG-ATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK-------EADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEF-----EKEWNITTDEEKGNFQ--------KNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNE-ININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-----LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKG-EIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAV-QTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXED---FKRTEYLSKFRK-EQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR---NTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLE-CSGFEQQCMETY-----LITNQLLD 3480
P +ES + W +H + Q YG I+ G G +P +YVR+ D + EL +L T W + PKL+I++ GG N L K ++GL+ +K+ WI TGG TGV+K VG+A + +++T V +GI WG N E L E P + + L+ H F+L D+G+ K+G E+ R + E+ +S + VV L++EGG NTI+ E + + +PVVV GS RAAD++ V + +SD + + + ++ +K + + D+ + +Q KNL+ + + + LD I+ A F K Q L +L LA+T+NR D+A IF V E N L M AL ++ FV L G++++ FLT L +LY + A+ L I KG I +L IG +IN+L + Y K+ +S + Y++Y + G + EM +P +L +WA+LT+R +MA + W G++ + +LV+ + ++ +A + EI Y +EFE+ +L +YR+D + LL L W +SCL +A L H Q L ++W+G + N F++++ + + +I + K + Q + QT + L D S+ Q +E ++ Y + + K D F+ LS++ + +QH+ L FYTAPITKF + I+Y+ FL MFS+ +L+++ + YS I YI+ L E + + + KF+ W +MWN D I+F I R NT++ IYC + +Y+R + V + +GP V M+ +M+K++++F+ + + L ++G ++LYPN T L++ + + PY+ L+G+V D G C T + + + + +LL N+LL++LLIA+F F +V S++VW F R+ ++ E+ +P+LPPPF FY+ K + + + + D + + ++DLE FE++C+E + +I NQ D
Sbjct: 69 PGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQG-----GAHPTKAQYVRLSFD---TRPELLVQLFTKEWNLELPKLLITVQGGKAN-FDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDA---LLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNRE-----VPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQE-------KPEGEAQELDQTILTALF----KSQHLSPPEQLSLALTWNRVDIARSEIF---VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYI-----YTLHDIGLVINKLMGGAYRSYYTRRKFRPIYA------KVMNSYANACRKSSTYQYQRY---------AGANSLSLVTGLLPFTSEMALFEFPF-----------NELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPF-----YIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLR---LKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYS--------IAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFRENTMDIGRVIYC-----VDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCV-RKAKGLEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTD 1174
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339077) HSP 1 Score: 308.916 bits (790), Expect = 8.454e-86 Identity = 318/1192 (26.68%), Postives = 533/1192 (44.71%), Query Frame = 1
Query: 97 PSVESDC-SEFW---RHEKFQ----YGAIQLSGYRVIAGKNP---KYVRVHKDLSNIKGELY-KLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFT----VLGIGTWG-ATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK-------EADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEF-----EKEWNITTDEEKGNFQ--------KNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNE-ININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-----LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKG-EIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAV-QTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXED---FKRTEYLSKFRK-EQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR---NTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLE-CSGFEQQCMETY-----LITNQLLD 3480
P +ES + W +H + Q YG I+ G G +P +YVR+ D + EL +L T W + PKL+I++ GG N L K ++GL+ +K+ WI TGG TGV+K VG+A +L + Q T +GI WG N E L E P + + L+ H F+L D+G+ K+G E+ R + E+ +S + VV L++EGG NTI+ E + + +PVVV GS RAAD++ V + +SD + + + ++ +K + + D+ + +Q KNL+ + + + LD I+ A F K Q L +L LA+T+NR D+A IF V E N L M AL ++ FV L G++++ FLT L +LY + A+ L I KG I +L IG +IN+L + Y K+ +S + Y++Y + G + EM +P +L +WA+LT+R +MA + W G++ + +LV+ + ++ +A + EI Y +EFE+ +L +YR+D + LL L W +SCL +A L H Q L ++W+G + N F++++ + + +I + K + Q + QT + L D S+ Q +E ++ Y + + K D F+ LS++ + +QH+ L FYTAPITKF + I+Y+ FL MFS+ +L+++ + YS I YI+ L E + + + KF+ W +MWN D I+F I R NT++ IYC + +Y+R + V + +GP V M+ +M+K++++F+ + + L ++G ++LYPN T L++ + + PY+ L+G+V D G C T + + + + +LL N+LL++LLIA+F F +V S++VW F R+ ++ E+ +P+LPPPF FY+ K + + + + D + + ++DLE FE++C+E + +I NQ D
Sbjct: 153 PGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQG-----GAHPTKAQYVRLSFD---TRPELLVQLFTKEWNLELPKLLITVQGGKANF-DLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDA-----LLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNRE-----VPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQE-------KPEGEAQELDQTILTALF----KSQHLSPPEQLSLALTWNRVDIARSEIF---VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYI-----YTLHDIGLVINKLMGGAYRSYYTRRKFRPIYA------KVMNSYANACRKSSTYQYQRY---------AGANSLSLVTGLLPFTSEMALFEFPF-----------NELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPF-----YIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLR---LKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYS--------IAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFRENTMDIGRVIYC-----VDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCV-RKAKGLEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTD 1258
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Zebrafish
Match: trpm1b (transient receptor potential cation channel, subfamily M, member 1b [Source:ZFIN;Acc:ZDB-GENE-070424-31]) HSP 1 Score: 294.278 bits (752), Expect = 4.530e-81 Identity = 324/1210 (26.78%), Postives = 528/1210 (43.64%), Query Frame = 1
Query: 202 YVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKN-----LVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIF-----------------------------------------------------ENQVRKNEININLRPFMETAL----IRNQWQFVDFFLRQGLTVESFLTNSMLRDLY-FKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSC--SCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR----YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKI-----PNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMG--GQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYME-------------GSQ---CLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNN--GRLS-VDAFIANLIHEEDLE-CSGFEQQCMETYLITNQLLDLSAHD 3495
Y+RV D L LM W + P L+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD+S S+ + + GI WG NKE L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E+L+ +PVVV GS RA+D+I S + + + L + E KE + T ++ N+ K L++ EC + + + +F M + +++++ AI+ A GT P +L LA+ +NR D+A +IF E RK E+ +N +E A+ + ++ FV + G+ + FLT L +LY K LH V + KG + + +L IG ++ L + Y N + + K PK D EP + + + E+ YP +L +WA+L +R +MA W+ G++ + ALVA C L+ A + E++++ + +EF TLA +L ++Y+ D+ LL L W +CL +A + +F+ H+ Q L ++W+G + P I LI PF I + + LG + V + + T+ + + ++ K +ED + K R+ + + I FY AP TKF N ISYL +L +++Y +L+++ + E+ + + I+ L ++ Q M G++K K N W WN DL VF + +LR N+ Y R ++ + + +YIR ++ + V + +GP V+MI +M+ D+L+F+ I L+ L ++G ++L+P+ T L RNIFY PYW ++G+V D ME G + C+ G TP AI+ A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP + Y F+ C+ S G L D + ++ ++L+ FE+QC+E Y + LS++D
Sbjct: 2 YIRVSHDTK--PDSLLHLMVKEWQLELPTLLISVHGGLQN-FDLQPKLKQVFGKGLIKAAVTTGAWIFTGGVSTGVIRHVGDALKDHSSKSRGKVCAI-GIAPWGILENKEDLIGKD----VNKPYQAISNPLSKLAVLNNSHSHFILSDNGTCGKYGAEVKLRRQLEKHISLQKINTRLGQGVPVVCLIVEGGPNVISIALESLREEPPVPVVVCDGSGRASDII-----SFAHKYSEVEGL-VNEDAKEQLLVTIQKTFNYNKMQSGQILLMVLECMKKRELITVFRMGAEGQDDIEMAILTALLKGTNASAP----DQLSLALAWNRVDIARNQIFVYGHNLPPASALASAITISAPSQEKQKGATQRNKGKARGKKGKGGKAKPEQPEETDPRKLEL-LNWVNSLEQAMMDALVLDRTDFVKLLIENGVNIHHFLTIPRLEELYNTKLGPGNTLHILVRDVKKGNLPPDYQITLIDIGLVVEYLMGGAYRCNYTRKNFRALYNNLYGLKRPKALKLLGMEDD-----------EPRSKGKKKQKKKKEEEEDIDVDDPEVSRFHYPF-----------HELMVWAVLMKRQKMALFLWQRGEEGMAKALVA---CKLLKGMAHESSQSEMVDDISQDLDNNSKEFGTLAYELLDQSYKHDEQLAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGSLRMGKNPGLKVILS-LIFPPF------ILLLDFR-LGDDTSHQVAVADEDKKTKDDERSTRDANADAASK-------------------KGDEEDGNK-----KMRR--------IPIGTKIFEFYNAPFTKFWFNTISYLGYLMLYNYVVLVKMER-------WPSLQEWIVISYIITLGLEKVRQILMSEPGKLKQ---KINVWLEEYWNITDLVAISVFLLGLLLRLQ-NEPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPDEEPTWRLARNIFYMPYWMIYGEVFADSIDLYAMEINPPCGENLYDEDGKKLPPCIPGAWLTP-AIM----ACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPLIILSHLYILFRKLCCRCSKKKEGELDEKDKGLKLILTPDELKMLYEFEEQCVEEYFREKEDEQLSSND 1111
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 289.656 bits (740), Expect = 1.543e-80 Identity = 285/1125 (25.33%), Postives = 489/1125 (43.47%), Query Frame = 1
Query: 103 VESDCSEFWRHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGG--AKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSIL--SKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA---------DCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESS---SDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQ--IGKVHLFNMKDFKNN--LDT----AIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILIN--VPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCAT-----------------PNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPF----NVFEVFYNFFK 3336
VE F + + G I +G GK +VRV S E+Y+++T WG P L+++L GG + P D ++GL+ ++S WI+T G G++K +G+A +D+S+ S K +GI W N++ L D TYP D G S LD H FIL D+ R G + R + + +S + + V+ L+V G +Q + ++++IP +++ GS AD++ +++ +D+ Q+ L + F G + + + Q + HL + D + + LDT A+++A S + + Q DE K LA+ +NR D+A+ IF V+ + +L M AL+ ++ FV F+ G+ ++ FLT L++LY LHT + + K + +M G N+L D F + E S + D F D +C+ Y+ K+ + + ++ + + +++ + +DLFLWA+L R EMA FW G + + +ALV + + A M N ++E A+++ SE Y + R + LL+R W + + L+IA + F H Q L +W G + +I ++++ +P TS I P + V + EP EL S + + + ++ + + F R L ++ + F++AP+T F+ N+I Y AFL +FSY LL++ P E +Y + + +L EI Q F + + + K + WN D+ +F + R + S + RT+ ++ +F +R + + + + +GPK+I++ RM+KD+ FFL + L AYG + +LL+PN + R Y PY +FGQ+ ++ ++ C T N +V + +LL TNVLLL+LLIAMF TF V+EN++ W F RY +I E++ RP L PPF ++ + +F K
Sbjct: 2 VEKSSERFDKQMAGRLGDIDFTGVSRTRGK---FVRVTS--STDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRD---TLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLLLSAKPDHPATYPTED-LPYGAVYS-LDCNHSHFILVDEDPKRP-GATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVTLMDRGCWDADIVQE---LLINTF----------PDGLHSTEITSWTKLIQRILDHGHLLTVHDPEQDSELDTVILKALVKACKSQSQEAQDFLDELK--LAVAWNRVDIAKSEIFSGDVQWSA--QDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELYCSVSEKNLLHTLL--LKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEV-----------SKVLKD---FLDDTCKGF-YQ------------------KLPAERMGKGRLFHSQKNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLATEAESARSMKN-----AKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNP--------EEQVSKDEGEPFAELDSLE-------TEQALLLTDGDPVAGEGSAETAARSCSATFIRV-VLRRWNR-----------------FWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRP---PPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQALLSFIK 1020
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 289.656 bits (740), Expect = 2.078e-80 Identity = 284/1123 (25.29%), Postives = 488/1123 (43.46%), Query Frame = 1
Query: 103 VESDCSEFWRHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGG--AKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSIL--SKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA---------DCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESS---SDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNN--LDT----AIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILIN--VPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCAT-----------------PNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPF----NVFEVFYNFFK 3336
VE F + + G I +G GK +VRV S E+Y+++T WG P L+++L GG + P D ++GL+ ++S WI+T G G++K +G+A +D+S+ S K +GI W N++ L D TYP D G S LD H FIL D+ R G + R + + +S + + V+ L+V G +Q + ++++IP +++ GS AD++ +++ +D+ Q+ L + F + T + + + HL + D + + LDT A+++A S + + Q DE K LA+ +NR D+A+ IF V+ + +L M AL+ ++ FV F+ G+ ++ FLT L++LY LHT + + K + +M G N+L D F + E S + D F D +C+ Y+ K+ + + ++ + + +++ + +DLFLWA+L R EMA FW G + + +ALV + + A M N ++E A+++ SE Y + R + LL+R W + + L+IA + F H Q L +W G + +I ++++ +P TS I P + V + EP EL S + + + ++ + + F R L ++ + F++AP+T F+ N+I Y AFL +FSY LL++ P E +Y + + +L EI Q F + + + K + WN D+ +F + R + S + RT+ ++ +F +R + + + + +GPK+I++ RM+KD+ FFL + L AYG + +LL+PN + R Y PY +FGQ+ ++ ++ C T N +V + +LL TNVLLL+LLIAMF TF V+EN++ W F RY +I E++ RP L PPF ++ + +F K
Sbjct: 51 VEKSSERFDKQMAGRLGDIDFTGVSRTRGK---FVRVTS--STDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRD---TLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLLLSAKPDHPATYPTED-LPYGAVYS-LDCNHSHFILVDEDPKRP-GATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVTLMDRGCWDADIVQE---LLINTFPDGLHSTEITSWTKLIQRI--------LDHGHLLTVHDPEQDSELDTVILKALVKACKSQSQEAQDFLDELK--LAVAWNRVDIAKSEIFSGDVQWSA--QDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELYCSVSEKNLLHTLL--LKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEV-----------SKVLKD---FLDDTCKGF-YQ------------------KLPAERMGKGRLFHSQKNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLATEAESARSMKN-----AKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNP--------EEQVSKDEGEPFAELDSLE-------TEQALLLTDGDPVAGEGSAETAARSCSATFIRV-VLRRWNR-----------------FWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRP---PPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQALLSFIK 1069
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 288.886 bits (738), Expect = 2.304e-80 Identity = 289/1125 (25.69%), Postives = 488/1125 (43.38%), Query Frame = 1
Query: 103 VESDCSEFWRHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGG--AKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSIL--SKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA---------DCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESS---SDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQ--IGKVHLFNMKDFKNN--LDT----AIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILIN--VPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCAT-----------------PNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPF----NVFEVFYNFFK 3336
VE F + + G I +G GK +VRV S E+Y+++T WG P L+++L GG + P D ++GL+ ++S WI+T G G++K +G+A +D+S+ S K +GI W N++ L D TYP D G S LD H FIL D+ R G + R + + +S + + V+ L+V G +Q + ++++IP +++ GS AD++ +++ +D+ Q+ L + F G + + + Q + HL + D + + LDT A+++A S + + Q DE K LA+ +NR D+A+ IF V+ + +L M AL+ ++ FV F+ G+ ++ FLT L++LY LHT + + K + +M G N+L D F + E S + D F D +C+ Y+K P SK + P + +++ + +DLFLWA+L R EMA FW G + + +ALV + + A M N ++E A+++ SE Y + R + LL+R W + + L+IA + F H Q L +W G + +I ++++ +P TS I P + V + EP EL S + + + ++ + + F R L ++ + F++AP+T F+ N+I Y AFL +FSY LL++ P E +Y + + +L EI Q F + + + K + WN D+ +F + R + S + RT+ ++ +F +R + + + + +GPK+I++ RM+KD+ FFL + L AYG + +LL+PN + R Y PY +FGQ+ ++ ++ C T N +V + +LL TNVLLL+LLIAMF TF V+EN++ W F RY +I E++ RP L PPF ++ + +F K
Sbjct: 2 VEKSSERFDKQMAGRLGDIDFTGVSRTRGK---FVRVTS--STDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRD---TLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLLLSAKPDHPATYPTED-LPYGAVYS-LDCNHSHFILVDEDPKRP-GATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVTLMDRGCWDADIVQE---LLINTF----------PDGLHSTEITSWTKLIQRILDHGHLLTVHDPEQDSELDTVILKALVKACKSQSQEAQDFLDELK--LAVAWNRVDIAKSEIFSGDVQWSA--QDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELYCSVSEKNLLHTLL--LKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEV-----------SKVLKD---FLDDTCKGF-YQKL-------PAV--------------SKALHQKNLP--DMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLATEAESARSMKN-----AKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNP--------EEQVSKDEGEPFAELDSLE-------TEQALLLTDGDPVAGEGSAETAARSCSATFIRV-VLRRWNR-----------------FWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRP---PPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQALLSFIK 1015
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Zebrafish
Match: trpm1a (transient receptor potential cation channel, subfamily M, member 1a [Source:ZFIN;Acc:ZDB-GENE-070112-1372]) HSP 1 Score: 276.559 bits (706), Expect = 1.866e-75 Identity = 311/1211 (25.68%), Postives = 519/1211 (42.86%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKLEEFEKEWNITTDEEKGNFQKN-----LVIFYECYQIGKVHLFNM----KDFKNNLDTAIIEAAFSGT---IKDQ-------------------------PLG----------DEAKLWLAMTFNRADVAEQRIF-----------ENQVRK----NEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSC--SCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEI--EIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIP-NFVNIFQILINVPFGYLTSRIFIFPYN--LLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMG--GQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYME-------------GSQ---CLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVD----AFIANLIHEEDLECSGFEQQCMETY 3456
YG I+ G I Y+RV D L LM W + P L+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD+S S+ + + GI WG NKE L + +T P S L+ H FIL D+G+ K+G E++ R + E+ +S + +V LI+EGG N I E+L+ + +PVVV GS RA+D+I + S + D+++ +L + T ++ N+ +N ++ EC + K L + + + +++ AI+ A GT DQ P G D+ K +A ++ A + E RK N +N +L M AL+ ++ FV + G+ + FLT L +LY + LH V + KG + + +L IG ++ L + Y + + + K PK D + I+ D+ +Y + +L +WA+L +R +MA W+ G++ + ALVA + ++ ++ ++ E+ +I + ++F LA +L ++Y+ D+ LL L W +CL +A + +F+ H+ Q L ++W+G + N ++++ + IFP LL R + NS+ E+ KD K + T+ KK ++ K+ + L +K I +F+ AP TKF N +YL +L +++Y +L+++ + E+ + + I+ L ++ Q M G++K K N W WN DL F + +LR N+ Y R ++ + + +YIR ++ + V + +GP V+MI +M+ D+L+F+ I L+ L ++G ++L+P+ T L RNIFY PYW ++G+V D ME G + C+ G TP AI+ A +LL N+LL++LLIA+F TF +V+ SN++W F RY++I F+ RP+LPPP +F Y K C+ +D L EE FE+Q +E Y
Sbjct: 6 YGIIEFQGGGHI--NKAMYIRVSYDTK--PDNLLHLMVKDWQLELPTLLISVHGGLQN-FDLQPKLKQVFGKGLIKAAVTTGAWIFTGGVSTGVIRHVGDALKDHSSKSRGKVCAI-GIAPWGIVENKEDLIGRD----VTRPYQTMSNPLSKLSVLNNSHSHFILADNGTHGKYGAEVRLRRQLEKHISLQKINTRLGQGVPLVCLILEGGPNVISIVLESLREDPPVPVVVCDGSGRASDIISFAHKYSEQDGLVNDSVRDQL--------LVTIQKTFNYNRNQAQQIYLMVMECMK--KRELITVFRTASEGQQDIEMAILTALLKGTNASAPDQLSLALAWNRVDIARSQIFVHGQHWPPAGSLPTSSTGQQDKPKSPIATRVSKGKPARGKKGKGAKSKPEPPEETDPRKLELLNWVN-SLEQAMMDALVLDRVDFVKLLIENGVNIHHFLTIPRLEELYNTRLGPINTLHFVVRDVKKGNLPPDYQITLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLYGLKRPKALKLLGMEDDDPRPK--------GKKKMKKKKEEEIDIDVDDPEVSRFQYPFH--------------ELMVWAVLMKRQKMALFLWQRGEEAMAKALVACKLYKAMAHES-SRSELVDDISQDLDNNSKDFGQLAYELLDQSYKHDEHMAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGCLRVGKSNGLKVILGI----------IFPPAILLLDFRTGDDLSYQNSKDKEEVKDKDDDTKSTK-----------DGTVSMDATSKKGDEEDGKKKQKRLPVGKK--------------IYYFFNAPYTKFWFNTTAYLVYLMLYNYIILVKMER-------WPSLQEWIVISYIITLGLEKVRQILMSEPGKLKQ---KINVWLEEYWNITDLAAITTFLMGLLLR-LQNEPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPDEEPTWRLARNIFYMPYWMIYGEVFADSIDLYAMEINPPCGENMYDEDGKKLPPCIPGAWLTP-AIM----ACYLLVANILLVNLLIAVFNNTFFEVKSISNQIWKFQRYQLIMTFHDRPVLPPPLIIFSHIYIVLKRLCCRCRKKQEGELDDRDHGLKLTLSAEELKSLYEFEEQNVEEY 1121
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662]) HSP 1 Score: 329.717 bits (844), Expect = 1.838e-93 Identity = 305/1144 (26.66%), Postives = 534/1144 (46.68%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANA----HLHTAVNFI---FKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDF-IYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANL---IHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG++ KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ N +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY + HL V + +G + + SL IG +I L + Y + + K PK + +++ E I P+ + T +I+ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + EF LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N + V G L P ++L + E+ D E + +K ++ +++ ++ + + K+ E ++H + I FY API KF ++Y+ +L +F+Y +L++++ ++ I I YI L E + + + + KF W WN DL ++F+I +LR + + F Y R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+P+ + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F K ++C L D L I E+DL + FE+QC+E Y
Sbjct: 109 FGTIEFQG----GGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTI-GIAPWGIVENQEDLVGKD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PIRSGRKTTKKREEEIDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSS---LKVILGIL------LPPSILSLEFKNKDEMPYMSQANEM---DLQEKEVEEPDKTVKEKEEDD-MELTAMLARGNGDSSRKKDE-------DEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP--------SMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADLVSILLFSIGMVLR--LQEQPFSSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICK-HLCCRWRKRELDQDERDYGLKLFITEDDLKKVHDFEEQCIEEY 1177
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662]) HSP 1 Score: 328.176 bits (840), Expect = 5.492e-92 Identity = 309/1149 (26.89%), Postives = 537/1149 (46.74%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIF--ENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVN-IFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDE--------VGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDF-IYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANL---IHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG++ KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ N +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF Q + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I P+ + T +I+ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + EF LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + +++E +Q K E+ +T L++ + DE + I FY API KF ++Y+ +L +F+Y +L++++ ++ I I YI F LG E + + + + KF W WN DL ++F+I +LR + + F Y R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+P+ + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F K ++C L D L I E+DL + FE+QC+E Y
Sbjct: 109 FGTIEFQG----GGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTI-GIAPWGIVENQEDLVGKD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIFIYGQQWPFSGRVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PIRSGRKTTKKREEEIDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGI----------LLPPSIL---------------SLEFKNKDEMPYMSQANEMDLQ----------------EKEVEEPDKTAMLARGNGDSSRKKDEDEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP--------SMQEWIVISYI-FTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADLVSILLFSIGMVLR--LQEQPFSSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICK-HLCCRWRKRELDQDERDYGLKLFITEDDLKKVHDFEEQCIEEY 1163
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662]) HSP 1 Score: 327.02 bits (837), Expect = 1.477e-91 Identity = 304/1146 (26.53%), Postives = 538/1146 (46.95%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANA----HLHTAVNFI---FKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVN-IFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDF-IYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANL---IHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG++ KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ N +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY + HL V + +G + + SL IG +I L + Y + + K PK + +++ E I P+ + T +I+ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + EF LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L + E+ D E + +K ++ +++ ++ + + K+ E ++H + I FY API KF ++Y+ +L +F+Y +L++++ ++ I I YI F LG E + + + + KF W WN DL ++F+I +LR + + F Y R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+P+ + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F K ++C L D L I E+DL + FE+QC+E Y
Sbjct: 109 FGTIEFQG----GGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTI-GIAPWGIVENQEDLVGKD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PIRSGRKTTKKREEEIDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGI----------LLPPSILSLEFKNKDEMPYMSQANEM---DLQEKEVEEPDKTVKEKEEDD-MELTAMLARGNGDSSRKKDE-------DEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP--------SMQEWIVISYI-FTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADLVSILLFSIGMVLR--LQEQPFSSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICK-HLCCRWRKRELDQDERDYGLKLFITEDDLKKVHDFEEQCIEEY 1177
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662]) HSP 1 Score: 326.635 bits (836), Expect = 1.598e-91 Identity = 304/1146 (26.53%), Postives = 538/1146 (46.95%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANA----HLHTAVNFI---FKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVN-IFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDF-IYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANL---IHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG++ KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ N +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY + HL V + +G + + SL IG +I L + Y + + K PK + +++ E I P+ + T +I+ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + EF LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L + E+ D E + +K ++ +++ ++ + + K+ E ++H + I FY API KF ++Y+ +L +F+Y +L++++ ++ I I YI F LG E + + + + KF W WN DL ++F+I +LR + + F Y R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+P+ + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F K ++C L D L I E+DL + FE+QC+E Y
Sbjct: 115 FGTIEFQG----GGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTI-GIAPWGIVENQEDLVGKD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PIRSGRKTTKKREEEIDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGI----------LLPPSILSLEFKNKDEMPYMSQANEM---DLQEKEVEEPDKTVKEKEEDD-MELTAMLARGNGDSSRKKDE-------DEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP--------SMQEWIVISYI-FTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADLVSILLFSIGMVLR--LQEQPFSSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICK-HLCCRWRKRELDQDERDYGLKLFITEDDLKKVHDFEEQCIEEY 1183
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662]) HSP 1 Score: 326.25 bits (835), Expect = 2.056e-91 Identity = 312/1149 (27.15%), Postives = 538/1149 (46.82%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIF--ENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVN-IFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDF-IYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFG-----QVDTSYMEGSQCLFGY--------------CATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANL---IHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG++ KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ N +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF Q + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I P+ + T +I+ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + EF LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + +++E +Q +K + D R K +++H + I FY API KF ++Y+ +L +F+Y +L++++ ++ I I YI F LG E + + + + KF W WN DL ++F+I +LR + + F Y R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+P+ + L +NIFY PYW ++G Q+D + S C GY C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F K ++C L D L I E+DL + FE+QC+E Y
Sbjct: 76 FGTIEFQG----GGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTI-GIAPWGIVENQEDLVGKD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIFIYGQQWPFSGRVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PIRSGRKTTKKREEEIDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGI----------LLPPSIL---------------SLEFKNKDEMPYMSQANEMDLQ----------EKEAMLARGNGDSSR-----KKDEDEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP--------SMQEWIVISYI-FTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADLVSILLFSIGMVLR--LQEQPFSSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQIDRNRKHISPC--GYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICK-HLCCRWRKRELDQDERDYGLKLFITEDDLKKVHDFEEQCIEEY 1129
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 322.783 bits (826), Expect = 2.377e-90 Identity = 306/1148 (26.66%), Postives = 536/1148 (46.69%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNIC--KNSNNGRLSVDAFIANLIHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I P+ T +++ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C + + + D + I +++L + FE+QC+E Y
Sbjct: 141 FGTIEFQG----GGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PLRRGRKTTKKREEEVDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMTQAQEI----HLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGLKLFITDDELKKVHDFEEQCIEEY 1204
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 320.472 bits (820), Expect = 2.377e-90 Identity = 307/1164 (26.37%), Postives = 530/1164 (45.53%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANA----HLHTAVN---------FIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEE-----SSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNIC--KNSNNGRLSVDAFIANLIHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY + HL V FKG + + SL IG +I L + Y + + K PK + +++ E I TT +EE E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ P+ + I I YI L E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C + + + D + I +++L + FE+QC+E Y
Sbjct: 139 FGTIEFQG----GGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDIPLRRGRKTTK-------KREEEVDIDLDDPEINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMTQAQEI----HLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERW---PST-----QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGLKLFITDDELKKVHDFEEQCIEEY 1214
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 317.39 bits (812), Expect = 1.397e-88 Identity = 305/1160 (26.29%), Postives = 533/1160 (45.95%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVIC--DVVESSSDMFQDTIKLK-LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------------------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNIC--KNSNNGRLSVDAFIANLIHEEDL-ECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + VV LIVEGG N I E L+ +PVVV GS RA+D++ + ++++ + L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I P+ T +++ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C + + + D + I +++L + FE+QC+E Y
Sbjct: 141 FGTIEFQG----GGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PLRRGRKTTKKREEEVDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSIL---------------SLEFKNKDDMPYMTQAQEI----HLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDRKQVYDSHTPKSAPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGLKLFITDDELKKVHDFEEQCIEEY 1216
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 313.153 bits (801), Expect = 2.757e-87 Identity = 306/1155 (26.49%), Postives = 532/1155 (46.06%), Query Frame = 1
Query: 202 YVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE---------------------ADC-----------SVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNIC--KNSNNGRLSVDAFIANLIHEEDL-ECSGFEQQCMETY 3456
YVRV D L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + C VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ +L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I P+ T +++ D + E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C + + + D + I +++L + FE+QC+E Y
Sbjct: 2 YVRVSFDTK--PDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDPIGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDI-PLRRGRKTTKKREEEVDIDLDDP-EINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSILS---------------LEFKNKDDMPYMTQAQEI----HLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGLKLFITDDELKKVHDFEEQCIEEY 1074
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Mouse
Match: Trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:MGI Symbol;Acc:MGI:1929996]) HSP 1 Score: 310.457 bits (794), Expect = 3.591e-86 Identity = 289/1156 (25.00%), Postives = 531/1156 (45.93%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGEL-YKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDV---VESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEA------------NSDSCSCCCWKSPKISDS-QSFNDSS--CEVIDYEKYIEPVAT-EPTTNCCCCFKINGDEESSKEMKYTVYPIRN-KNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYL----SKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR-----NTVNDSD---FIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D K E+ +L+ W + PKL+IS++GG + L+ K +GLI + + WI+TGG TGV+K VG+A K+++ S ++ T+ GI WG N+ L + + P + L+ H FIL DDG+ K+G E++ R E E++++++ VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ + E ++ + +K +N E FQ + + I H+ + + ++D AI+ A GT + D+ L L + ++R D+A+ +F + + +L M AL+ ++ FV + G+++ FLT L +LY ++ N L + + +G + K +L IG +I L + Y N S +P++ S ++F + + E + + +I+ P + +E K K + I + + K+ Y +L +WA L +R MA+ W+ G++ + ALVA + S+ +A ++ + ++ Y +F LA+ +L +++R+D+ LL L W +CL +A ++L F+ H+ Q L+++W+G++ N ++++++ I + P L+ + +T+A ++ + S+D + + SE N+ N T + E FK + L K E H ++ FY API KF N ++YL FL ++++ +L+++ + P+ E+ + + ++ + ++ + FM + K W S +N D I F + + LR N +N D F+ R ++ +++ +Y+R ++F V Q GP V+MI +M+ ++ + + I + L ++G ++LYP+ + L ++I ++PYW +FG+V + L C + A +L +++++LLIA F +++V+ SN VW + RY I ++ +P+LPPP + + F +CK + S D L E+ + FE+QC+E Y
Sbjct: 92 YGVINFQGGSHSYRA------KYVRLSYD---TKPEIILQLLLKEWQMELPKLVISVHGGMQKF-ELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTI-GIAPWGVIENRNDLVGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQSEAVHLFQTMMECMKKKELITVFHIGS--EDHQDIDVAILTALLKGT--NASAFDQ--LILTLAWDRVDIAKNHVF--VYGQQWLVGSLEQAMLDALVMDRVSFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLIRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHETFGNRADKKEKMRHNHFIKTAQPYRPKMDASM------EEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILS---------ILVPPAILMLEYKTKAEMSHIPQ------SQDAHQMTMEDSEN----NFHNITEEIPM--------EVFKEVKILDSSDGKNEMEIHIKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVKMEQL---PSVQ----EWIVIAYIFTYAIEKVREVFMS-EAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLF-CCVCKRRKKDKTS-DGPKLFLTEEDQKKLHDFEEQCVEMY 1181
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. UniProt/SwissProt
Match: sp|A7T1N0|TMP2L_NEMVE (Transient receptor potential cation channel subfamily M member-like 2 OS=Nematostella vectensis OX=45351 GN=TRPM2 PE=1 SV=1) HSP 1 Score: 365.54 bits (937), Expect = 3.766e-104 Identity = 306/1156 (26.47%), Postives = 556/1156 (48.10%), Query Frame = 1
Query: 130 RHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDL-SNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQT-FTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK-------EAD---CSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESS--SDMFQDTIKLKLEEFEKEWNITTDEEKG--NFQKNLVIFYECYQIGK-VHLFNMK-DFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIF-ENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKM--IGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEI-EIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFX-----XXXXXXXXXEDFKRTEYLSKFRKEQHESL----DEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYS-RKIEYCIYIFYISFLLGEIYQFFMGGQVKNFI-SKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINI-----TSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCATPNA--IVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFK--LNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQ 3471
+H YG I GY K Y+R+ D +N+ + LM W + P L+IS+ GGAK+ + L + F+RGLI +K+ WI+TGG TGV K VGEA K+ ++ T V+GI TWG + L + + +P +G + LDP H F L DDG++ K+G EI R+ EE++ K EA VV L++EGG NT+ T E +K +P VV+ GS RAA V+ + ++ TI + ++E E E G K + + + K + ++++ + ++D AI++A + P+ A+L LA+ +NR D+A+ IF E Q E L M TAL+ ++ +F + FL+ GL++ FL+ +L LY + N T + + + + + +++ M +G +I +L ++F Y++ D F + + Y E + + + +SSK++ + N+ + D+FLWA+L R E+A++ W+ G++ + +AL+A+ + + +A I +I ++ + FE A+ +L E + ++ + LL+R L ++ R + L++A + +F+ H++CQ L +W+G + +++L+ + YL IF Y + ++ + + S H++K+ ++ P Y++ + +EDF+ +Y+ + R++ + ++GFC I FY+AP +KFV N++ YLAF+ +++Y +L + T E +Y + + L+ EI Q + + +I K + + S WN+ D+ VF IA ILR N F R + S+ + F +R ++ + V + +GPK++MI +M++D+ F+ I + AYG ++++P+ I T + ++ PYWQ++G++ ++G + P+ + + A +++FTN+LLL+LLIA+F TF +V+E+S++VW F RY +++E++ RP+ PP + F + +C+ + R S L E + +E Q E Y+ Q
Sbjct: 89 KHPTNAYGEIDFEGYG--GQKRAPYLRMSHDTDANL---VITLMLKRWNLEIPNLVISVTGGAKSFV-LKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQVNVIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQG-AMLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAYNHTIKRNVDGQTINVIDPQYEDEVRAKVVEVFGAKGADKTYSMIKDVLEDEKMISVYSLDGEISQDIDLAILKALLKAN-RSSPV---AQLNLALAWNRIDLAKSDIFTEEQQWTTE---TLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYAEVPGN----TTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRK-----------------DGHYFGELAS-------YAEGLVLK-------------NRKSSKDLLANI----NRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCL---YLPVLIFPIIYFVPDEQHERQAAEREHQKSLNQKSSKVKSHKEKNDAPVV-PVYRSKEEKAVSNDEEARVGTENEEEDFQLEDYIPEIREDDSMEVIMRNKKLGFCDRIMHFYSAPFSKFVGNVVGYLAFIFLYAYVVLFNFPRFDPAKTLGGIHPTEIVLYFWVFTILIEEIRQ--LAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEIQGEKPKEFGEVDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVWRMCRCGHPPRGST--MKIGLSPAEMEQMDNWEFQAAEMYIHQQQ 1177
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. UniProt/SwissProt
Match: sp|Q96QT4|TRPM7_HUMAN (Transient receptor potential cation channel subfamily M member 7 OS=Homo sapiens OX=9606 GN=TRPM7 PE=1 SV=1) HSP 1 Score: 313.538 bits (802), Expect = 2.449e-86 Identity = 295/1160 (25.43%), Postives = 534/1160 (46.03%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGE-LYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDV---VESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEA------------NSDSCSCCCWKSPKISDS-QSFNDSS--CEVIDYEKYIEPVAT-EPTTNCCCCFKINGDEESSKEMKYTVYPIRN-KNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYL----SKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFM--GGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR--------NTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D K E + +L+ W + PKL+IS++GG + L+ K +GLI + + WI+TGG TGV+K VG+A K+++ S ++ T+ GI WG N+ L + + P + L+ H FIL DDG+ K+G E++ R E E++++++ VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ + E ++ + +K +N +E FQ EC + + + +F++ D ++D AI+ A GT + D+ L L + ++R D+A+ +F + + +L M AL+ ++ FV + G+++ FLT L +LY ++ N L V + +G + K +L IG +I L + Y N S +P++ S +SF + + E + + +I+ P + +E K K + I + + K+ Y +L +WA L +R MA+ W+ G++ + ALVA + S+ +A ++ + ++ Y +F LA+ +L +++R+D+ LL L W +CL +A ++L F+ H+ Q L+++W+G++ N ++++++ I + P LL + +T+A ++ + S+D + SE N+QN T + E FK L K E ++ FY API KF N ++YL FL ++++ +L+++ + P+ E+ + + ++ + ++ + FM G+V K W S +N D I F I + LR N ++ F+ R ++ +++ +Y+R ++F V Q GP V+MI +M+ ++ + + I + L ++G ++LYP+ + L ++I ++PYW +FG+V + + C + A +L +++++LLIA F +++V+ SN VW + RY I ++ +P+LPPP + + F ICK + S D L E+ + FE+QC+E Y
Sbjct: 92 YGVINFQGGSHSYRA------KYVRLSYD---TKPEVILQLLLKEWQMELPKLVISVHGGMQKF-ELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTI-GIAPWGVIENRNDLVGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQ----TLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGT--NASAFDQ--LILTLAWDRVDIAKNHVF--VYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVM------EEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILS---------ILVPPAILLLEYKTKAEMSHIPQ------SQDAHQMTMDDSEN----NFQNITEEIPM--------EVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQL---PSVQ----EWIVIAYIFTYAIEKVREIFMSEAGKVNQ---KIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLF-CCICKRRKKDKTS-DGPKLFLTEEDQKKLHDFEEQCVEMY 1181
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. UniProt/SwissProt
Match: sp|Q925B3|TRPM7_RAT (Transient receptor potential cation channel subfamily M member 7 OS=Rattus norvegicus OX=10116 GN=Trpm7 PE=1 SV=2) HSP 1 Score: 311.227 bits (796), Expect = 1.191e-85 Identity = 291/1156 (25.17%), Postives = 531/1156 (45.93%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGEL-YKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDV---VESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEA------------NSDSCSCCCWKSPKISDS-QSFNDSS--CEVIDYEKYIEPVAT-EPTTNCCCCFKINGDEESSKEMKYTVYPIRN-KNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYL----SKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR-----NTVNDSD---FIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D K E+ +L+ W + PKL+IS++GG + L+ K +GLI + + WI+TGG TGV+K VG+A K+++ S ++ T+ GI WG N+ L + + P + L+ H FIL DDG+ K+G E++ R E E++++++ VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ + E ++ + +K +N E FQ + + I H+ + + ++D AI+ A GT + D+ L L + ++R D+A+ +F + + +L M AL+ ++ FV + G+++ FLT L +LY ++ N L + + +G + K +L IG +I L + Y N S +P++ S ++F + + E + + +I+ P + +E K K + I + + K+ Y +L +WA L +R MA+ W+ G++ + ALVA + S+ +A ++ + ++ Y +F LA+ +L +++R+D+ LL L W +CL +A ++L F+ H+ Q L+++W+G++ N ++++++ I + P L+ + +T+A ++ + S+D + + SE N+ N T + E FK + L K E H ++ FY API KF N ++YL FL ++++ +L+++ + P+ E+ + + ++ + +I + FM + K W S +N D I F + + LR N +N D F+ R ++ +++ +Y+R ++F V Q GP V+MI +M+ ++ + + I + L ++G ++LYP+ + L ++I ++PYW +FG+V + L C + A +L +++++LLIA F +++V+ SN VW + RY I ++ +P+LPPP + + F ICK + S D L E+ + FE+QC+E Y
Sbjct: 92 YGVINFQGGSHSYRA------KYVRLSYD---TKPEIILQLLLKEWQMELPKLVISVHGGMQKF-ELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTI-GIAPWGVIENRNDLVGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQSEAVHLFQTMMECMKKKELITVFHIGS--EDHQDIDVAILTALXXGT--NASAFDQ--LILTLAWDRVDIAKNHVF--VYGQQWLVGSLEQAMLDALVMDRVSFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLIRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNASSSTPQLRKSHETFGNRADKKEKMRHNHFIKTAQPYRPKMDASM------EEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILS---------ILVPPAILMLEYKTKAEMSHIPQ------SQDAHQMTMEDSEN----NFHNITEEIPM--------EVFKEVKILDSSEGKNEMEIHIKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQL---PSVQ----EWIVIAYIFTYAIEKIREVFMS-EAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSALPTICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLF-CCICKRRKKDKTS-DGPKLFLTEEDQKKLHDFEEQCVEMY 1181
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. UniProt/SwissProt
Match: sp|Q9HCF6|TRPM3_HUMAN (Transient receptor potential cation channel subfamily M member 3 OS=Homo sapiens OX=9606 GN=TRPM3 PE=2 SV=4) HSP 1 Score: 310.842 bits (795), Expect = 1.531e-85 Identity = 308/1181 (26.08%), Postives = 533/1181 (45.13%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE---------------------ADC-----------SVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEINI-NLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAH-LHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCW--KSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEE-----SSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY-QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRF---------FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLG-EIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIY-CRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----------DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICK------NSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
+G I+ G G + K + V L LMT W + PKL+IS++GG +N L K F +GLI + + WI TGG TGV + VG+A KD++ S+ + T+ GI WG N+E L + + P + L+ H FIL D+G+ K+G E+K R + E+ +S + C VV LIVEGG N I E L+ +PVVV GS RA+D++ + S + + ++++ +L +K + T + + F +I EC + + + +F M + ++D AI+ A G P +L LA+ +NR D+A +IF + + + +L M AL+ ++ FV + G+++ FLT S L +LY ++ L+ V + KG + + SL IG +I L + Y + + K PK + +++ E I TT +EE E+ + +P +L +WA+L +R +MA FW+ G++ + ALVA +C ++ +A ++ ++ + + +F LA+ +L ++Y++D+ LL L W +CL +A + +F+ H+ Q L ++W+G++ N ++++ + + P ++L E +KD + ++ E + Q + + K K +ED + T L + E DE S R FY API KF ++Y+ +L +F+Y +L+++ + E+ I I YI F LG E + + + + K W WN DL ++F++ ILR + D F R ++ +++ +YIR ++ + V + +GP V+MI +M+ D+++F+ I L+ L ++G ++L+PN + L +NIFY PYW ++G+V + + +G C T IV A +LL N+LL++LLIA+F TF +V+ SN+VW F RY++I F+ RP+LPPP +F F+ C+ + + + FI + +E + FE+QC+E Y
Sbjct: 139 FGTIEFQG----GGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQN-FELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTI-GIAPWGIVENQEDLIGRD----VVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLF----IILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIF---IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPK----------ALKLLGMEDDIPLRRGRKTTK-------KREEEVDIDLDDPEINHFPFPF-----------HELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI----------LLPPSILS---------------LEFKNKDDMPYMSQAQEI----HLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMER-------WPSTQEW-IVISYI-FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR--LQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD---DELKKVHDFEEQCIEEY 1227
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. UniProt/SwissProt
Match: sp|Q923J1|TRPM7_MOUSE (Transient receptor potential cation channel subfamily M member 7 OS=Mus musculus OX=10090 GN=Trpm7 PE=1 SV=1) HSP 1 Score: 310.071 bits (793), Expect = 2.903e-85 Identity = 289/1156 (25.00%), Postives = 531/1156 (45.93%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGEL-YKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDV---VESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEA------------NSDSCSCCCWKSPKISDS-QSFNDSS--CEVIDYEKYIEPVAT-EPTTNCCCCFKINGDEESSKEMKYTVYPIRN-KNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYL----SKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILR-----NTVNDSD---FIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D K E+ +L+ W + PKL+IS++GG + L+ K +GLI + + WI+TGG TGV+K VG+A K+++ S ++ T+ GI WG N+ L + + P + L+ H FIL DDG+ K+G E++ R E E++++++ VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ + E ++ + +K +N E FQ + + I H+ + + ++D AI+ A GT + D+ L L + ++R D+A+ +F + + +L M AL+ ++ FV + G+++ FLT L +LY ++ N L + + +G + K +L IG +I L + Y N S +P++ S ++F + + E + + +I+ P + +E K K + I + + K+ Y +L +WA L +R MA+ W+ G++ + ALVA + S+ +A ++ + ++ Y +F LA+ +L +++R+D+ LL L W +CL +A ++L F+ H+ Q L+++W+G++ N ++++++ I + P L+ + +T+A ++ + S+D + + SE N+ N T + E FK + L K E H ++ FY API KF N ++YL FL ++++ +L+++ + P+ E+ + + ++ + ++ + FM + K W S +N D I F + + LR N +N D F+ R ++ +++ +Y+R ++F V Q GP V+MI +M+ ++ + + I + L ++G ++LYP+ + L ++I ++PYW +FG+V + L C + A +L +++++LLIA F +++V+ SN VW + RY I ++ +P+LPPP + + F +CK + S D L E+ + FE+QC+E Y
Sbjct: 92 YGVINFQGGSHSYRA------KYVRLSYD---TKPEIILQLLLKEWQMELPKLVISVHGGMQKF-ELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTI-GIAPWGVIENRNDLVGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQSEAVHLFQTMMECMKKKELITVFHIGS--EDHQDIDVAILTALLKGT--NASAFDQ--LILTLAWDRVDIAKNHVF--VYGQQWLVGSLEQAMLDALVMDRVSFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLIRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHETFGNRADKKEKMRHNHFIKTAQPYRPKMDASM------EEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILS---------ILVPPAILMLEYKTKAEMSHIPQ------SQDAHQMTMEDSEN----NFHNITEEIPM--------EVFKEVKILDSSDGKNEMEIHIKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVKMEQL---PSVQ----EWIVIAYIFTYAIEKVREVFMS-EAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLF-CCVCKRRKKDKTS-DGPKLFLTEEDQKKLHDFEEQCVEMY 1181
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. TrEMBL
Match: A0A077LAN8 (Transient receptor potential ion channel M b (Fragment) OS=Dugesia japonica OX=6161 GN=DjTRPMb PE=2 SV=1) HSP 1 Score: 1124.77 bits (2908), Expect = 0.000e+0 Identity = 553/845 (65.44%), Postives = 681/845 (80.59%), Query Frame = 1
Query: 376 VSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQ--IGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSC--EVIDYEKYIEPVATEPTTNCCCCFKI-NGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSK------DFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVG 2877
VSKSA TWIVTGGFE GVSKLVGEASKDYSILSK+QTFTVLGIGTWG TYN +KL M +E+D++TY N D QKV KGQS L+P+HDAFILYDDG+D+KFG+EI+FR +FEE +SK A CSVVQLIVEGGKNTI+TGAEAL SNIPVVVMKGS+RAADVICDVVE+S DM +TI+LK EF EWN+ + ++K NFQ+NL F + Y+ +VHLFNM+DFKNNLDTAIIEAAFSGTI D+ LGD+AKL LAMTFNRADVAE+RIFE++ +INLR +M+ AL+RNQWQFVDFFLRQG+TVESFLT +L DLYF ++A + A IF G ++S E Q+LK +G++I++LT N+FP MY+EA DSCSCCCW + KI+D+Q D+S EV D+EKYIEP ++NCC + N + ++ +KYT++P RN+ K+IIYTEQDLFLWALLTQRIEMAKIFWK GKDHIGSALVA+++C+SLQKKAGAKGEIEI NN ++QE+FET++I+ILSEAYRRDQIRTHLLLIR LPYWGRESCLDIANKNQ+INFLFHSACQTRLN+IWLGKIPN VN FQIL+N+PFG+LTSR+FIFPYNL GK+Q + +E + +K +F+ +Q SS+ Q +YQ L+ K KK K +E+ KRTEYLSKFRKE+H S+D++ FCSA+++FYTAP+TKFVMNIISYLAFLT+FSYFLLIELN ++LSP +R EY +Y+++IS+++GEI QFFMGGQ N SKFNNWKSSMWNWFDL YIVFT+ YILR + +S+ +YCRTLF++SLSMF+I ++++G
Sbjct: 1 VSKSAPTWIVTGGFEAGVSKLVGEASKDYSILSKQQTFTVLGIGTWGCTYNNKKLLMNSENDKVTYHNDDIQKVKKGQSQLNPHHDAFILYDDGTDKKFGQEIEFRAQFEEFISKTAKCSVVQLIVEGGKNTIRTGAEALDSNIPVVVMKGSRRAADVICDVVEASDDMLDETIELKYSEFVDEWNMKSKDDKANFQQNLRNFAKRYKDKHKQVHLFNMRDFKNNLDTAIIEAAFSGTIDDKNLGDDAKLKLAMTFNRADVAEERIFEDKT-----DINLRLYMKQALVRNQWQFVDFFLRQGITVESFLTKKLLHDLYFDKEAIGYFIPAALLIF-GNMNSKEIQNLKTVGKIISRLTSNIFPAMYREAEPDSCSCCCWNNVKITDTQLSIDNSTDYEVKDHEKYIEPKVITESSNCCHVKRDGNSNGDNGNRIKYTIHPTRNREKEIIYTEQDLFLWALLTQRIEMAKIFWKNGKDHIGSALVASLICNSLQKKAGAKGEIEIQNNLKKFQEDFETMSIDILSEAYRRDQIRTHLLLIRGLPYWGRESCLDIANKNQMINFLFHSACQTRLNHIWLGKIPNIVNNFQILVNIPFGFLTSRLFIFPYNLFGKKQNDSANEKLNEEQQSISNKFQSPESEFNISKQTSSDNFFQNDYQIVNLKSKNWKKNKKSQEELKRTEYLSKFRKEEHFSMDKIHFCSAVKYFYTAPVTKFVMNIISYLAFLTIFSYFLLIELNIMSLSPNPINRATEYSVYVYFISYVIGEIRQFFMGGQANNLASKFNNWKSSMWNWFDLLTYIVFTVGYILRCS-GESNIVYCRTLFAMSLSMFFISLWNSIMFKKALG 838
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. TrEMBL
Match: R7TUH6 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_199955 PE=4 SV=1) HSP 1 Score: 462.611 bits (1189), Expect = 4.976e-138 Identity = 341/1173 (29.07%), Postives = 587/1173 (50.04%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRV-HKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSK--KQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPN-YDPQKVG----KGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSV----------VQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVIC---------DVVESSSDMFQ--DTIKLKLEEFEKEWN-----ITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCC-CFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQIL------INVPFGYLTSRIFIFPYNLLGKRQTQAVQ--------TNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGY-------------CATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDL-ECSGFEQQCMETYLITNQLL 3477
+G I+ G+ KN +VRV HK ++ +++L+ W K PKL+IS+ GGAK + + AFKRGL+ + + WI+TGG TGV K VGEA ++ + + + LGI TWG N+E L +DD +P Y+ +++ +G SPLDP H FIL D+G++ KFG EIKF ++ +S+ + V V L++EGG+NT++ +++K P+VV+ GS RAAD I DV E S D L + +W+ +T + + N+ + ++ V D N++D AI++A D + +L LA+ +NR D+A + IF + R +NL M TAL++++ FV FL G+ ++ FL+ LRDLY ++ + A + ++ L+ + D F + + S + + S +EKYI +N + + +S+ + P K ++ ++LF+WA+L R ++A +FWKCG D IG AL A+ V SSL A ++ EI++ + FE LA+ +L+ Y+++++ +H LL+R LP WG + L +A+ L++F+ H+ CQTRLNNIW+GK+ + + ++IL + +PF S F + + + Q VQ E LS + K ++ N +K K R + + F+ +S + AI F++T P+ KF + ISY+ FL ++S+F+L +L+ +S E ++ + ++ ++ EI Q ++ V + ++ ++ S+WN FD +Y + I+ I+R T+ + F++ R +++++L+MF++RF+ ++V +++GPKVIMI RML D+LFF++I ++ + A+G S SL YPN ++ +++N+ Y PYWQ++G++ + G + C +V + A +++ N+LLL+LLIAMF TF KV++NS +VW F RY +I E++ +P L PP + F K I + N +S D N++ ++D + + FE+ M+ +L+ Q+L
Sbjct: 86 FGTIRFQGFGQEVSKNAPFVRVDHKTEESV---VWELLNEYWHIKAPKLMISVTGGAKRFF-MKDRLTTAFKRGLMRAATTTGAWIITGGTNTGVMKFVGEAVHEHMLTTSDAESNVVALGIATWGIVDNRESLT--ADDDAGLFPAFYNIEELSSPHTRGSSPLDPNHTHFILVDNGTETKFGVEIKFSVALQQYISENMETGVARNQSVNVPTVLLVLEGGENTLEMTVQSVKKFTPIVVIHGSGRAADYIALAYRKTRSVDVSEEKSVYPSNFDEEMLGHAAYMFDWSREKDPVTKEAKIKKCLDNIKLLLASRRLITVFALEDGDTSNDIDQAILQALLKANRADA----QTQLNLALAWNRCDIARREIFTPENRACWQKMNLYEAMHTALVQDRTDFVQLFLDNGVDLKRFLSIRRLRDLYDDVLSDPYSGAASD----------------LLKHLLQE--DTQFSFLCNPKDDLSVETSAYLLRSVGQLLSGMGQHSNFYAHEKYIVHDDNLGFSNAAYDTLRTPREMDSTNPFASSKKPC--KAAELSNPHRELFVWAVLLNRKDLALLFWKCGSDQIGGALFASHVLSSLSNIANSEEEIDLSQELHANADMFEELAVGVLNACYQKNKLMSHRLLVRVLPKWGDSTLLTMADSGALMHFMGHTCCQTRLNNIWMGKLALYTSSWKILAALFLPVIIPFLKFNSTDF----HSITFGEIQNVQEEEEEEEEEVGGGSKEEGLSSAVKAQPNQVVPKQVETEQCNAFTAMRKRKPPNMNIRKLYRVNFFNLFK----DSDSSINVLKAIYFYHTTPLVKFCYHTISYVIFLAVYSFFVLTDLHPERISAC------EGLVWAWSLTLIMEEIRQVWVKRAV-SLSARLASYFDSVWNRFDFMLYGLLIISIIIRYTLTEYSFLWARRIYAVNLAMFFLRFLHTFFVDRNIGPKVIMIRRMLVDLLFFISILVVFILAFGVASHSLRYPNAELSWSILKNVVYMPYWQMYGELFLEDLTGDVGPCSHNSTVYTSSEDIVRCPETEWLVLLLLAIYMIVINILLLNLLIAMFSYTFEKVQDNSEKVWRFYRYGLIYEYFDKPTLAPPIIIISHFIRLLKYCIRRKRNITDVSND--FRNIVSKDDYNKLTAFEKAGMDNFLLREQVL 1211
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. TrEMBL
Match: A0A210PMT1 (Transient receptor potential cation channel subfamily M member 3 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05997 PE=4 SV=1) HSP 1 Score: 467.233 bits (1201), Expect = 2.219e-137 Identity = 369/1186 (31.11%), Postives = 597/1186 (50.34%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGEL-YKLMTNVWGFKKPKLIISLNGGAK--NMIPLNNDQKL--AFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV-LGIGTWGATYNKEKLAMQTEDDRITYP------NYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK------------EADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVIC-------DVVESSSDMFQDTIKLKLEEFEK---EWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNMKDFKN-NLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYF-----KEKANAHLHTAVNFIFKGTIDS-----------PEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEG---SQCLF----------GYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSV-DAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLSAHDASKT 3507
YG I+ GY +P Y+R+ D + EL ++ N W PKL+IS+ GGAK +M P KL FKRGLI+ + S WI+TGG TGV ++VGE ++Y + KQ V LG+ WG NK+ L ED+ +P D +K GK PLD H F++ DDGS KFG EI+FR E+++S + + V+ LIVEGG T++T +E++K+ IPV+V++G+ RAAD I D++ F + +EE EW + L C + + + +FN+ D +N +LD AI+ A +Q A+L LA+ +NR+DVA IF + +K +L M TALI+N+ FV FL G+ ++ FLT L +LY K +A L + K T + + + ++++G+ I + + Y + +D C ++P C I D+ + K M + R+ E++LFLWALL R+++AK+FWK GKDH+G+AL+A + L K A + EIE+ + FE LA+++LS Y+ ++ H LL+R L +G + L +A+ ++L++F+ H++CQT+LN++W G++ + + ++IL + +L I F N K T+ + +++ L E S + P ++ + Q KR Y D + SAI FYTAP+TKF ++YLAFL +FSYF+L L+ S IEY + + I+ ++ E+ Q Q ++ + K +W SS+WN FDL +Y++F ++ ILR +++ +F + R +SI+L+M+++RFM+ ++V++++GPKVIMI +ML D++FF AI + + ++G + L+PN + L+R + Y PYWQ++G++ MEG S C CA NAIV + A ++L TN+LL++LLIAMF TF KV++NS +VW F ++ ++ E+Y RP + PPF + + F + + + +L+ D F +L ++ + FE++ +E YL T + L D+ T
Sbjct: 354 YGEIEFHGYGHDTESSP-YIRLAND---TQPELVLDIILNYWKLPTPKLLISVTGGAKRFDMKP-----KLLEKFKRGLINAATSTGAWIITGGTHTGVMEIVGEGVQEYVLTYGKQKDIVCLGVPLWGVIANKDAL---DEDENGNFPAIYSKEGLDAEK-GKKTIPLDHNHTHFVIVDDGSRDKFGGEIEFRANLEKTISHMSCDSEGMSSNLQVNTPVISLIVEGGVGTMKTVSESIKNGIPVLVLEGTGRAADFIAAGYLFTKDIMNEDRSHFPPHYQQTMEEIATNNFEWKPGETNKPAKISLCLKQLESCLKSRRMITVFNLGDAENKDLDKAILNALLKANKSNQ----SAQLSLALAWNRSDVARNTIFSSS-KKTIFGASLHDAMTTALIQNKKTFVKLFLENGVELKDFLTVKNLWNLYANCLNDKTDRSAQLFNNLIMYLKQTWGAYLCCRPVEHLGNQPELVELVGKTIVHIVGDEAINPYDGSKTDRFKVCD-------------------------VDP----------CMGYIVDDKATEKSMAGKKW--RHVKHDFELPERELFLWALLLNRMDLAKLFWKLGKDHLGTALLAAALLKGLAKVADGEEEIELSVSLEESALMFEKLAVDVLSHCYKHNKALAHQLLVRQLVDYGNTTLLLLADAHELMDFMDHTSCQTKLNSVWKGRMALYTSTYKILAAMVIPFLIPAI-KFTSN---KNPTEYLDDDDALDYDNLGEAMAGEGTAIISNSRVAPETESRSKQI-------------KRKLYQVSL---AGTGKDGISLVSAIYHFYTAPVTKFYWYTVAYLAFLAIFSYFVLTNLHPT--SSVNSPSNIEYVTWGWTITMVIEEVRQVLTRDQ-RSLVHKLRSWYSSVWNRFDLIMYLLFMLSVILRFVLSEDNFTWARMTYSITLAMYFLRFMQAFFVEKNIGPKVIMIRKMLTDLMFFFAILAVFVLSFGIAYQANLFPNDPPSWKLLRQVVYLPYWQMYGELFLENMEGEEPSSCTTNETLWRSGAQARCAENNAIVPLLLAVYMLLTNILLVNLLIAMFSDTFQKVQDNSLKVWRFYKFSLVYEYYERPSVFPPFIILN--HAFRGVRWLMHKSFRKLNYHDDFKLHLSARDNTRLTLFEREAVEDYLHTTRELKREQLDSKVT 1459
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. TrEMBL
Match: A0A1S3HH51 (transient receptor potential cation channel subfamily M member 2 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106154535 PE=4 SV=1) HSP 1 Score: 452.595 bits (1163), Expect = 2.483e-132 Identity = 369/1203 (30.67%), Postives = 601/1203 (49.96%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV--LGIGTWGATYNKEKLAMQTEDDRITYP----NYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSV----------VQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAAD-VICDVVESSSDM------------FQDTIKLKLEEFEKEWNITTDEEKGNFQK---NLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYF---------------KEKANAHLHTAVNFIFKGTIDS---PEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQ---KSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTE-YLSKFRKEQHESLDEVGFCS----------AIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQ--VDTSYMEGSQC-----LFGYCATPNAIVQ-------VANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFN-----VFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLI-TNQLLDLSAHDASK 3504
+G I SG+ Y+RV D + + L+ L+ + W P+LII++ GGA+ L AFK GLI+ + W+V+GG TGV KLVGEA +D+S S ++ + LG+ TWG NKE L E++ +P + D + G G + LDP H +I DDG++ K+G EIK R + E+ +S++ + + + L++EGG NT+QT AEA+K + PVV++ GS RAAD +IC + S F+D + + + + +E + N +K NL I + ++ V N ++D AI+ A D +L LA+ +NR DVA Q+IF R+N ++L P M TAL++++ +FV FL G+ ++ FLT S L++LY+ KEK + + + G D + L IGR+IN+ + +Y C +++ + N EV + ++ + ++ + EE E + E+ L LWA+L R E+AK+FWK GKDHIG+AL A+ + + K A E+++ + + EFE LA+ +L+E Y +D+I H L+ R LP++G ++ + IA+ + ++F+ + CQT+LN IWLGK+ +I++I VP ++ F+ P+ + S+P K FSE R S +I + N + ++ +F R++ K RK S +V C A +F+TAPITKF+ I Y+ FL MFSYFL+++L+ + + +I ++IF + +L E+ Q ++ K +W S+WN DL +Y +F I+ +LR T+ ++DF++ R + ++L + ++RF++ + + + +GPKVIMI RM+ D++FF+ I L+ L AYG +LLYPN +++++ Y PYWQ++G +D + + QC L+ P Q V ++L TNVLLL+LLIA+F TF +++NS VW F R+ +I E++ RP LPPP V + Y K KNS+ D+F L +E + + FE+ ME+YL+ T+Q + AH A+K
Sbjct: 309 FGEILFSGFGYDNKVPAPYIRV--DHTTERSTLWHLLDDYWKLPAPRLIITVTGGAQKFF-LRPRLLHAFKTGLINAATGTGAWVVSGGTNTGVMKLVGEAVRDHSFASDVESSKIIALGVATWGIISNKESLV--GEENMGCFPALYRSEDLRHGGAGTAALDPNHTHYIFVDDGTENKYGAEIKLRAKLEQYISEKVETGISKTESVPVPIILLVLEGGINTLQTVAEAVKQDTPVVIIGGSGRAADYLICGYKMTRSKEKGKEEESQYPSNFEDEMAEEAKSLFDLHGLDQEEVEKNIKKCLKNLKICLDHRKLLTVFRLNDSTSARDMDKAILYALLKANKSDA----RTQLNLALAWNRPDVARQQIFTQDNRENWQKVDLYPAMYTALVQDRLEFVHLFLDMGVDLKKFLTASKLQELYYDVLKDRFSGAGAFYLKEKVQQLQQSFASRLRSGDGDHGDLDQNSVLYNIGRVINRCVQDQQDNLYASQKPGMCENQPSAEAGLAEDMT-NQRYTEVNEVDERVNTISQCAPGAKMKKKRTKLKEEQKCEFERP--------------EKHLMLWAVLLNRKELAKLFWKMGKDHIGAALFASAILKRMSKDAAGDEEVDLAEDLKNHGVEFEELAVGVLNECYSKDKILGHRLVTRQLPHFGHDTVMTIADTARQMHFMEQACCQTKLNMIWLGKMVQHTSIWKI---VPSLFIP---FVIPFIKFRIK---------SKP-----LKSFSEVRGIDLGSVNRIAPEAEKKNGDEEEENSDPDGDGVEFTRSKTRREKNRKGAKHSYFQVNCCGLDKDSISIFRAFYYFHTAPITKFLYQQIMYIVFLCMFSYFLMVDLHPMNTPDNLHIWEI--FVWIFSGTSILEEVRQVLTKDS-RSLWYKLADWWKSVWNKLDLIMYTLFIISVVLRFTLTEADFVHARRAYCLTLILHFVRFLQGFMIHKDMGPKVIMIRRMITDVIFFVMILLVFLLAYGVAVQALLYPNHKRDWSILKDVVYIPYWQMYGDLFLDETSGKIDQCTSNATLYLQDNGPQMCPQQNEWMTIVLMVIYMLLTNVLLLNLLIAIFNYTFQNIQDNSLTVWRFYRFGLIYEYHDRPPLPPPAIIISHIVRGIMYIVKKCRGIKNSD------DSFKRVLSVDEQEKLTVFEKAGMESYLLRTHQ--ENEAHMANK 1456
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. TrEMBL
Match: A0A1S3HED0 (transient receptor potential cation channel subfamily M member 2 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106154535 PE=4 SV=1) HSP 1 Score: 447.203 bits (1149), Expect = 2.676e-130 Identity = 374/1211 (30.88%), Postives = 599/1211 (49.46%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV--LGIGTWGATYNKEKLAMQTEDDRITYP----NYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSV----------VQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAAD-VICDVVESSSDMFQDTIKLKLEE------FEKEWNITTDEEKGNFQ-----------------KNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYF---------------KEKANAHLHTAVNFIFKGTIDS---PEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQ---KSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTE-YLSKFRKEQHESLDEVGFCS----------AIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQ--VDTSYMEGSQC-----LFGYCATPNAIVQ-------VANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFN-----VFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLI-TNQLLDLSAHDASK 3504
+G I SG+ Y+RV D + L+ L+ + W P+LII++ GGA+ L AFK GLI+ + W+V+GG TGV KLVGEA +D+S S ++ + LG+ TWG NKE L E++ +P + D + G G + LDP H +I D+G++ K+G EIK R + E+ +S++ + + + L++EGG NT+QT AEA+K + PVV++ GS RAAD +IC M + K K EE FE E +E K F KNL I + ++ V N ++D AI+ A D +L LA+ +NR DVA Q+IF R+N ++L P M TAL++++ +FV FL G+ ++ FLT S L++LY+ KEK + + + G D + L IGR+IN+ + +Y C +++ + N EV + ++ + ++ + EE E + E+ L LWA+L R E+AK+FWK GKDHIG+AL A+ + + K A E+++ + + EFE LA+ +L+E Y +D+I H L+ R LP++G ++ + IA+ + ++F+ + CQT+LN IWLGK+ +I++I VP ++ F+ P+ + S+P K FSE R S +I + N + ++ +F R++ K RK S +V C A +F+TAPITKF+ I Y+ FL MFSYFL+++L+ + + +I ++IF + +L E+ Q ++ K +W S+WN DL +Y +F I+ +LR T+ ++DF++ R + ++L + ++RF++ + + + +GPKVIMI RM+ D++FF+ I L+ L AYG +LLYPN +++++ Y PYWQ++G +D + + QC L+ P Q V ++L TNVLLL+LLIA+F TF +++NS VW F R+ +I E++ RP LPPP V + Y K KNS+ D+F L +E + + FE+ ME+YL+ T+Q + AH A+K
Sbjct: 309 FGEILFSGFGYDNKVPAPYIRV--DHTTELSTLWHLLDDYWKLPAPRLIITVTGGAQKFF-LRPRLLHAFKTGLINAATGTGAWVVSGGTNTGVMKLVGEAVRDHSFASDVESSKIIALGVATWGIISNKESLV--GEENMGCFPALYRSEDLRNGGAGTAALDPNHTHYIFVDNGTENKYGAEIKLRAKLEQYISEQVETGISITESVPVPIILLVLEGGINTLQTVAEAVKQDTPVVIIGGSGRAADYLIC-----GYKMTRSKEKGKEEESQYPSNFEDE---MAEEAKSLFDLHGLDQEEVEKIIKKCLKNLKICLDHRKLLTVFRLNDSTSARDMDKAILYALLKANKSDA----RTQLNLALAWNRPDVARQQIFTQDNRENWQKVDLYPAMYTALVQDRLEFVHLFLDMGVDLKKFLTASKLQELYYDVLKDRFSGAGAFYLKEKVQQLQQSFASRLRSGDGDHGDLDQNSVLYNIGRVINRCVQDQQDNLYASQKPGMCENQPSAEAGLAEDMT-NQRYTEVNEVDERVNTISQCAPGAKMKKKRTKLKEEQKCEFERP--------------EKHLMLWAVLLNRKELAKLFWKMGKDHIGAALFASAILKRMSKDAAGDEEVDLAEDLKNHGVEFEELAVGVLNECYSKDKILGHRLVTRQLPHFGHDTVMTIADTARQMHFMEQACCQTKLNMIWLGKMVQHTSIWKI---VPSLFIP---FVIPFIKFRIK---------SKP-----LKSFSEVRGIDLGSVNRIAPEAEKKNGDEEEENSDPDGDGVEFTRSKTRREKNRKGAKHSYFQVNCCGLDKDSISIFRAFYYFHTAPITKFLYQQIMYIVFLCMFSYFLMVDLHPMNTPDNLHIWEI--FVWIFSGTSILEEVRQVLTKDS-RSLWYKLADWWKSVWNKLDLIMYTLFIISVVLRFTLTEADFVHARRAYCLTLILHFVRFLQGFMIHKDMGPKVIMIRRMITDVIFFVMILLVFLLAYGVAVQALLYPNHKRDWSILKDVVYIPYWQMYGDLFLDETSGKIDQCTSNATLYLQDNGPQMCPQQNEWMTIVLMVIYMLLTNVLLLNLLIAIFNYTFQNIQDNSLTVWRFYRFGLIYEYHDRPPLPPPAIIISHIVRGIMYIVKKCRGIKNSD------DSFKRVLSVDEQEKLTVFEKAGMESYLLRTHQ--ENEAHMANK 1456
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 318.161 bits (814), Expect = 7.026e-89 Identity = 292/1147 (25.46%), Postives = 537/1147 (46.82%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQL---------TDNLFPQMYQ--EANSDSCSCCCWKSPKISDSQ---SFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFM--GGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++S S ++ T+ GI WG N+ L + + P + L+ H FIL D+G+ K+G E+ R + E+ ++ + VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ V + + D D ++ + +K +N++ ++ FQ EC + + + +F++ + ++D AI++A GT D D+ L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT S L +LY +++ N +L V + +G + K +L +G +I L T F +Y N+ P + + S E + +I+ +P K+ + S +E+ P + ++ Y +L +WA+L +R +M+ FW+ G++ + ALVA +C S+ +A ++ + ++ Y EF TLA+++L +++R+D++ + LL L W +CL +A ++L F+ H+ Q L+++W+ ++ N +++++++ + I Y K + + S+ ++ +D SEH ++ + I ++ + E TE +++ R+ + FY API KF N + YL FL ++SY +L++L I SP E+ + ++ + + +I + FM GG++ K W S +N D ++F + + LR + FI R ++ +++ +Y+R ++ V Q GP V+MI +M+ ++ + + I + L YG ++LYPN L+ ++ + PYW ++G+V D + C T + A +L +L+++LLIA F +++V SN VW + RY I ++ +P+LPPP +F +F + + F L E+ + FE+QC+ETY
Sbjct: 70 YGIINFQGGSHSYRA------KYVRLSHD--SRPEAILRLMLKEWQMELPKIVISVHGGIQNF-DLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTI-GIAPWGVIENRNDLIGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQ----TLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQ--LVLTLAWDRVDIAKDHVF---VYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIK--TAQPYKP-----KVEKQKRSREEVVDIDDP---ETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSI---LVPPAILALEY----KSKAEMAHIPQSQDAHQMTMED-SEHNLQNPDDIQMDVFKETRIN--------DHVEVKHETEVVTRSRR--------LPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKL-PIFPSPQ------EWAVILYIFTSAIEKIREMFMSEGGKISQ---KIKVWFSDYFNRSDFIAIVMFAVGFGLRFGSGNV-FIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLF---LTEEDQKKLHDFEEQCVETY 1143
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 316.235 bits (809), Expect = 4.113e-88 Identity = 288/1150 (25.04%), Postives = 535/1150 (46.52%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLT-----------------DNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFM--GGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++S S ++ T+ GI WG N+ L + + P + L+ H FIL D+G+ K+G E+ R + E+ ++ + VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ V + + D D ++ + +K +N++ ++ FQ EC + + + +F++ + ++D AI++A GT D D+ L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT S L +LY +++ N +L V + +G + K +L +G +I L +NL + + S K+ + Q+ + K +P + + + D + + + V + ++ Y +L +WA+L +R +M+ FW+ G++ + ALVA +C S+ +A ++ + ++ Y EF TLA+++L +++R+D++ + LL L W +CL +A ++L F+ H+ Q L+++W+ ++ N +++++++ + I Y K + + S+ ++ +D SEH ++ + I ++ + E TE +++ R+ + FY API KF N + YL FL ++SY +L++L I SP E+ + ++ + + +I + FM GG++ K W S +N D ++F + + LR + FI R ++ +++ +Y+R ++ V Q GP V+MI +M+ ++ + + I + L YG ++LYPN L+ ++ + PYW ++G+V D + C T + A +L +L+++LLIA F +++V SN VW + RY I ++ +P+LPPP +F +F + + F L E+ + FE+QC+ETY
Sbjct: 91 YGIINFQGGSHSYRA------KYVRLSHD--SRPEAILRLMLKEWQMELPKIVISVHGGIQNF-DLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTI-GIAPWGVIENRNDLIGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQ----TLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQ--LVLTLAWDRVDIAKDHVF---VYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIKTAQPYKPK--------LESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSI---LVPPAILALEY----KSKAEMAHIPQSQDAHQMTMED-SEHNLQNPDDIQMDVFKETRIN--------DHVEVKHETEVVTRSRR--------LPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKL-PIFPSPQ------EWAVILYIFTSAIEKIREMFMSEGGKISQ---KIKVWFSDYFNRSDFIAIVMFAVGFGLRFGSGNV-FIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLF---LTEEDQKKLHDFEEQCVETY 1169
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 315.849 bits (808), Expect = 4.518e-88 Identity = 290/1147 (25.28%), Postives = 536/1147 (46.73%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQL---------TDNLFPQMYQ--EANSDSCSCCCWKSPKISDSQ---SFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFM--GGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++S S ++ T+ GI WG N+ L + + P + L+ H FIL D+G+ K+G E+ R + E+ ++ + VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ V + + D D ++ + +K +N++ ++ FQ EC + + + +F++ + ++D AI++A GT D D+ L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT S L +LY +++ N +L V + +G + K +L +G +I L T F +Y N+ P + + S E + +I+ +P + + D + + + V + ++ Y +L +WA+L +R +M+ FW+ G++ + ALVA +C S+ +A ++ + ++ Y EF TLA+++L +++R+D++ + LL L W +CL +A ++L F+ H+ Q L+++W+ ++ N +++++++ + I Y K + + S+ ++ +D SEH ++ + I ++ + E TE +++ R+ + FY API KF N + YL FL ++SY +L++L I SP E+ + ++ + + +I + FM GG++ K W S +N D ++F + + LR + FI R ++ +++ +Y+R ++ V Q GP V+MI +M+ ++ + + I + L YG ++LYPN L+ ++ + PYW ++G+V D + C T + A +L +L+++LLIA F +++V SN VW + RY I ++ +P+LPPP +F +F + + F L E+ + FE+QC+ETY
Sbjct: 108 YGIINFQGGSHSYRA------KYVRLSHD--SRPEAILRLMLKEWQMELPKIVISVHGGIQNF-DLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTI-GIAPWGVIENRNDLIGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQ----TLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQ--LVLTLAWDRVDIAKDHVF---VYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIK--TAQPYKPK---LESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSI---LVPPAILALEY----KSKAEMAHIPQSQDAHQMTMED-SEHNLQNPDDIQMDVFKETRIN--------DHVEVKHETEVVTRSRR--------LPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKL-PIFPSPQ------EWAVILYIFTSAIEKIREMFMSEGGKISQ---KIKVWFSDYFNRSDFIAIVMFAVGFGLRFGSGNV-FIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLF---LTEEDQKKLHDFEEQCVETY 1186
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 315.464 bits (807), Expect = 5.680e-88 Identity = 290/1147 (25.28%), Postives = 536/1147 (46.73%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQL---------TDNLFPQMYQ--EANSDSCSCCCWKSPKISDSQ---SFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFM--GGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++S S ++ T+ GI WG N+ L + + P + L+ H FIL D+G+ K+G E+ R + E+ ++ + VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ V + + D D ++ + +K +N++ ++ FQ EC + + + +F++ + ++D AI++A GT D D+ L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT S L +LY +++ N +L V + +G + K +L +G +I L T F +Y N+ P + + S E + +I+ +P + + D + + + V + ++ Y +L +WA+L +R +M+ FW+ G++ + ALVA +C S+ +A ++ + ++ Y EF TLA+++L +++R+D++ + LL L W +CL +A ++L F+ H+ Q L+++W+ ++ N +++++++ + I Y K + + S+ ++ +D SEH ++ + I ++ + E TE +++ R+ + FY API KF N + YL FL ++SY +L++L I SP E+ + ++ + + +I + FM GG++ K W S +N D ++F + + LR + FI R ++ +++ +Y+R ++ V Q GP V+MI +M+ ++ + + I + L YG ++LYPN L+ ++ + PYW ++G+V D + C T + A +L +L+++LLIA F +++V SN VW + RY I ++ +P+LPPP +F +F + + F L E+ + FE+QC+ETY
Sbjct: 91 YGIINFQGGSHSYRA------KYVRLSHD--SRPEAILRLMLKEWQMELPKIVISVHGGIQNF-DLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTI-GIAPWGVIENRNDLIGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQ----TLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQ--LVLTLAWDRVDIAKDHVF---VYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIK--TAQPYKPK---LESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSI---LVPPAILALEY----KSKAEMAHIPQSQDAHQMTMED-SEHNLQNPDDIQMDVFKETRIN--------DHVEVKHETEVVTRSRR--------LPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKL-PIFPSPQ------EWAVILYIFTSAIEKIREMFMSEGGKISQ---KIKVWFSDYFNRSDFIAIVMFAVGFGLRFGSGNV-FIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLF---LTEEDQKKLHDFEEQCVETY 1169
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 315.464 bits (807), Expect = 5.780e-88 Identity = 288/1150 (25.04%), Postives = 535/1150 (46.52%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSD--MFQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLT-----------------DNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFM--GGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETY 3456
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++S S ++ T+ GI WG N+ L + + P + L+ H FIL D+G+ K+G E+ R + E+ ++ + VV LI EGG N I T E L+ + +PVVV +G+ RAAD++ V + + D D ++ + +K +N++ ++ FQ EC + + + +F++ + ++D AI++A GT D D+ L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT S L +LY +++ N +L V + +G + K +L +G +I L +NL + + S K+ + Q+ + K +P + + + D + + + V + ++ Y +L +WA+L +R +M+ FW+ G++ + ALVA +C S+ +A ++ + ++ Y EF TLA+++L +++R+D++ + LL L W +CL +A ++L F+ H+ Q L+++W+ ++ N +++++++ + I Y K + + S+ ++ +D SEH ++ + I ++ + E TE +++ R+ + FY API KF N + YL FL ++SY +L++L I SP E+ + ++ + + +I + FM GG++ K W S +N D ++F + + LR + FI R ++ +++ +Y+R ++ V Q GP V+MI +M+ ++ + + I + L YG ++LYPN L+ ++ + PYW ++G+V D + C T + A +L +L+++LLIA F +++V SN VW + RY I ++ +P+LPPP +F +F + + F L E+ + FE+QC+ETY
Sbjct: 101 YGIINFQGGSHSYRA------KYVRLSHD--SRPEAILRLMLKEWQMELPKIVISVHGGIQN-FDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTI-GIAPWGVIENRNDLIGRD----VVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQ----TLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQ--LVLTLAWDRVDIAKDHVF---VYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIKTAQPYKPK--------LESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSI---LVPPAILALEY----KSKAEMAHIPQSQDAHQMTMED-SEHNLQNPDDIQMDVFKETRIN--------DHVEVKHETEVVTRSRR--------LPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKL-PIFPSPQ------EWAVILYIFTSAIEKIREMFMSEGGKISQ---KIKVWFSDYFNRSDFIAIVMFAVGFGLRFGSGNV-FIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLF---LTEEDQKKLHDFEEQCVETY 1179
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 266.929 bits (681), Expect = 2.127e-74 Identity = 263/1050 (25.05%), Postives = 475/1050 (45.24%), Query Frame = 1
Query: 199 KYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA-------DCSVVQLIVEGGKNTIQTGAEAL--KSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNM-KDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIF---ENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMI--GRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRY---QEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVN-IFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKI-----IQPNYQNNTLQFXXXXXXXXXXEDFKRTE-YLSKFRKEQHESLDEVGFCSAIRF--FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFD-LGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYME-GSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYR 3258
+Y RV D + L +LM W + P+L+IS++GG +N L+ K F +GLI + + WI TGG TGV VG A K+++ S + T+ GI WG N+ L Q D + P + L+ H FIL DDG+ K+G E + R E E+ ++ A VV L+ EGG N I T E L + +PVVV +G+ RAAD++ + +++ D + L +E T + G L EC + + + +F+ + +++D AI+ A GT +L LA+ ++R D+A+ +F ++ + + E RP ++ AL+ ++ FV + G+++ FLT + L +LY ++ H + + + P + +I G +I L F MY K ++ + V + + + ++T + S E YP +L WA+L +R MA FW+ G++ + ALVA + SL +A E E+ W R + +F LA+++L +++R+D+ LL L W +CL +A ++ F+ H+ Q L ++W+G++ N F++++++ + I + Y K + + SE + + ++ EHR ++ I + L F L+ + + S ++E+ + G + R FY API KF N ++Y+ FL +F+Y +L++L + P+ E+ + ++ + + + FM + F K W WN D LGI ++F +A LR+ I + ++S+ + +Y+R ++ + V Q+VGP ++MI +M+ + I I L ++G ++L+ + + L RNI + PYW +FG+V ++ + + C T I A +L +++++LLIA F +++ + S+++W F RY
Sbjct: 1 QYARVSYD--SRPDLLLQLMVKEWQMELPRLLISVHGGLQN-FELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKEHASRSSHKICTI-GIAPWGVIENRGDLVGQ--DSHVVSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAEAQLRRELEKHIATVACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILAFLHKNTDDTGELCDGLH-DEIVGTIKKTFNFSHGQAMHLLQTLLECMRRKELITVFHTGSEDHSDVDLAILTALLKGT----NFSSADQLNLALAWDRVDIAKNHVFVYGQHWMVRLEWARWRRPMLD-ALVMDRVDFVKLLIENGVSMHKFLTITRLEELY--NTSDHHQMSNLRILLHRFSHLPPDYKITLIDVGLVIEFLMGGAFRSMYTR-----------KRFRLLYHNLYGQHRASVDNTRQRKQKMSTASGVGVTL-------DGSDPECSCFAYPF-----------NELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSREDEL--KWKRLWCARVKFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSI---LMPPSILMLEY----KSKAEMSHIPQSEELHQ-MGQEEREHRAAATRDIPMQRCLSRRVFLRLLSFAIRILLLRTVGNGSAADGGESGHKEEEGIWIRPSGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQL---PSVQ----EWFVILYLFMSAIERVREIFM-SEPGKFGQKIKVWLDGYWNINDSLGI-LLFFVAVALRS--QSHLLIEAKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMWQQCMLMIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFGEVYAPEIDNNTDDEYPPCTTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYH 986
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 235.343 bits (599), Expect = 5.790e-64 Identity = 262/1103 (23.75%), Postives = 454/1103 (41.16%), Query Frame = 1
Query: 244 LYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEA------------DCSVVQLIVEGGKNTIQTGAEAL--KSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQ----IGKVHLFNMKDFKNNLDTAIIEAAFS----------GTIKDQPLGDEAKLWLAMTFNRADVAEQRIFE-NQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSC---CCWKSPKISD-SQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTEL---LSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFIS------------KFNNWKSSMWNWFD-LGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEG------SQC----------LFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICK 3351
L +LM W + P+L+IS++GG +N L+ K F +GLI + + WI TGG TGV VG A K+++ S + T+ GI WG N+ L Q D + P + L+ H FIL DDG+ K+G E + R E E+ ++ + VV L+ EGG N I T E L + +PVVV +G+ RAAD++ + +++ D W T G L EC + +G +A I S G +L LA+ ++R D+A+ +F Q + R M AL+ ++ FV + G+++ FLT + L +LY N + G + +P K+ L ANS S C P I + +C I + +T ++G S E YP +L WA+L +R MA FW+ G++ + ALVA + SL +A +E + ++ Y EF LA+++L +++R+D+ LL L W +CL +A ++ F+ H+ Q L ++W+G++ N F++++++ + I + Y K + + SE ++ + D E K E I + R LS R+ I FY API KF N ++Y+ FL +F+Y +L++L + P+ E+ + ++ + + + G + + K W WN D LGI ++F +A LR+ I + ++S+ + +Y+R ++ + V Q+VGP ++MI +M+ ++ + I I L ++G ++L+ + + L RNI + PYW +FG+V ++G + C + C T I A +L +++++LLIA F +++ + S+++W F RY +Y++ + PP + + + F +C+
Sbjct: 13 LLQLMVKEWQMELPRLLISVHGGLQN-FELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKEHASRSSHKICTI-GIAPWGVIENRGDLVGQ--DSHVVSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAEAQLRRELEKHIALQKIHTLACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILAFLHKNTDD--------------TGWAHT--HRHGQAMHLLQTLLECMRRKELVGTRARVRTHTHTCTHGSAAISGGPSVETLIALHRTGAAAGTNFSSADQLNLALAWDRVDIAKNHVFVYGQHWMALMWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELY-------------NTV-SGPLTNPPKRPLL--------------------ANSRSPPVGLNCTLNPPVIGNLLLMILGGTCSAIQAVDNTRQRKQKMSTASGVGVTLDG---SDPECSCFAYPF-----------NELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSEAVEDSSEELKQYSTEFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSI---LMPPSILMLEY----KSKAEMSHIPQSEELHQMGNGSAADGGESGHKEEEGI------------------------WIRPSGLSLSRR--------------IYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQL---PSVQ----EWFVILYLFMSAIERVREVSDGARETRKAAGLRSDSEASAHRKIKVWLDGYWNINDSLGI-LLFFVAVALRS--QSHLLIEAKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMANMFSIVIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFGEVYAPEIDGICVAVLAACENIMKNNTDDEYPPCTTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYH-FTMYYHQKPILPPPLILLSYLSLFASQLCR 991
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Sea Lamprey
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412]) HSP 1 Score: 207.608 bits (527), Expect = 7.700e-55 Identity = 189/696 (27.16%), Postives = 307/696 (44.11%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSAS---TWIVTGGFETGVSKLVGEASKDYSIL--SKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYP-NYDPQKVGKGQ-SPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGN--FQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKG--TIDSPEKQ---SLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLT-SRIFIFPYNL 2190
+G IQ +G + + K+VRV D L+KLM W P L+IS+ GGAKN L + F+ GL ++S WI+TGG GV K VGE+ +D+++ SK+ +GI TWG +NKE L D + +P Y + G+G+ S LD H FIL D+G+ ++G EI R E+ +S + S G E S V + R D+ V + I +E N + EK N F + +F+ I + L + + I A+ K Q D +L LA+ +NR D+A IF + RK + +L M+ AL+ N+ +F+ F+ GL + +LT + L LY A++ LH + I +G + P ++ +L M + +N + + +E DS S K+S + SS K G + +++ E+DLF+WA+L R E+A FW GKD + +AL+A+ + ++ ++ + + + ++ + + +E LAI +L E Y+ D++R LLIR L WG +CL +A +F HS Q L IW G + + +++++ + F L +RI F + L
Sbjct: 72 FGDIQFTG---LGQRLGKFVRVGNDTE--PSVLFKLMMEHWHLDVPNLLISVTGGAKNF-HLKPQLRTIFRHGLNKTARSTGIQGAWIITGGSYAGVMKYVGESVRDFALASGSKEGKIVAIGIATWGIIHNKEHLI----DAQGKFPAEYPMDEAGQGRLSCLDNNHSHFILVDNGTHGQYGVEIVLRARLEQYISTQHTGS---------------GGECRSSKAVGVRGNCAARLWDMCVRVRHCGKIVL--IIMQAXSMVVREINSSVIFEKQNIYFDVLICLFFLGRIISRALL--TGTYACAMVVVCISASRGEANKAQESCDH-QLRLALAWNRVDIATSEIFTDD-RKWQTG-DLEQVMDAALLENRPEFISLFVEHGLILREYLTWARLESLYNGAPASSLLHILLRRISEGEKSPADPHRRWISTLPMAPKRMNHFSLYHISLLIRELLGDSTSML--YGNKMSRFSKLSPSS-------------------------KNTGSTKGGTSLEFKGQTYNEGQLYCPDPERDLFIWAVLLNRRELANFFWSQGKDCMAAALMASKLLKAMVQE---EDDSDRTSDMLAQADNYEQLAIGLLDECYKDDELRAQKLLIRQLHSWGGATCLSMAYHANNKSFFSHSGVQALLTQIWWGGMSVDLKTWRVILCIIFPLLIYTRIITFRWVL 705 HSP 2 Score: 138.658 bits (348), Expect = 2.860e-33 Identity = 113/373 (30.29%), Postives = 184/373 (49.33%), Query Frame = 1
Query: 2440 CSAIRF--FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSS------MWNWFDLGIYIVFTIAYILR---NTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQ----VDTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXX---------XXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLS 3486
C+ R+ F+TAPIT F N++SY FL +F+Y ++++ P EY +Y + +S +L E+ Q F + K WK++ +WN D+ ++FTI I R N++N+S F R++ + +F +R M + V +++GPK+I++ RM+KDI FFL + + + AYG + +L N + R + Y PY +FGQ VD++ + + C T V +L LLL+LLIAMF TF V++N++ +W F RY ++ E++ RP L PP VF Y F + I K + + F E+ E +E E+Y + +QL + S
Sbjct: 710 CTPTRWRNFWTAPITVFWANVVSYFIFLWLFAYVIIMDFQYTPDWP-------EYVLYAWVLSLILEELRQVFTDPE------KAGQWKAAVRYIKDIWNRIDILALLLFTIGVICRLIPNSINESTFQAGRSVLCVDYMVFCLRLMHIFTVNKTLGPKIIIVKRMVKDIFFFLFLLGVWVVAYGVATQGILILNEQRLDWIFRGVVYQPYLLIFGQFPTRVDSTTFDTTSCTNNGINTSQPRCPVLGVDWLTILLTCLYLLFANILLLNLLIAMFNYTFQLVQDNTDTIWKFQRYELVNEYHSRPSLAPPLIVFSHLYLFVRRFILKKPQHKH---EDFKKGFSESEEREFLAWESIMRESY-VASQLTEKS 1065
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Nematostella
Match: EDO30135 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1N0]) HSP 1 Score: 365.54 bits (937), Expect = 1.544e-105 Identity = 306/1156 (26.47%), Postives = 556/1156 (48.10%), Query Frame = 1
Query: 130 RHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDL-SNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQT-FTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSK-------EAD---CSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESS--SDMFQDTIKLKLEEFEKEWNITTDEEKG--NFQKNLVIFYECYQIGK-VHLFNMK-DFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIF-ENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKM--IGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEI-EIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFX-----XXXXXXXXXEDFKRTEYLSKFRKEQHESL----DEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYS-RKIEYCIYIFYISFLLGEIYQFFMGGQVKNFI-SKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINI-----TSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCATPNA--IVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFK--LNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQ 3471
+H YG I GY K Y+R+ D +N+ + LM W + P L+IS+ GGAK+ + L + F+RGLI +K+ WI+TGG TGV K VGEA K+ ++ T V+GI TWG + L + + +P +G + LDP H F L DDG++ K+G EI R+ EE++ K EA VV L++EGG NT+ T E +K +P VV+ GS RAA V+ + ++ TI + ++E E E G K + + + K + ++++ + ++D AI++A + P+ A+L LA+ +NR D+A+ IF E Q E L M TAL+ ++ +F + FL+ GL++ FL+ +L LY + N T + + + + + +++ M +G +I +L ++F Y++ D F + + Y E + + + +SSK++ + N+ + D+FLWA+L R E+A++ W+ G++ + +AL+A+ + + +A I +I ++ + FE A+ +L E + ++ + LL+R L ++ R + L++A + +F+ H++CQ L +W+G + +++L+ + YL IF Y + ++ + + S H++K+ ++ P Y++ + +EDF+ +Y+ + R++ + ++GFC I FY+AP +KFV N++ YLAF+ +++Y +L + T E +Y + + L+ EI Q + + +I K + + S WN+ D+ VF IA ILR N F R + S+ + F +R ++ + V + +GPK++MI +M++D+ F+ I + AYG ++++P+ I T + ++ PYWQ++G++ ++G + P+ + + A +++FTN+LLL+LLIA+F TF +V+E+S++VW F RY +++E++ RP+ PP + F + +C+ + R S L E + +E Q E Y+ Q
Sbjct: 89 KHPTNAYGEIDFEGYG--GQKRAPYLRMSHDTDANL---VITLMLKRWNLEIPNLVISVTGGAKSFV-LKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQVNVIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQG-AMLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAYNHTIKRNVDGQTINVIDPQYEDEVRAKVVEVFGAKGADKTYSMIKDVLEDEKMISVYSLDGEISQDIDLAILKALLKAN-RSSPV---AQLNLALAWNRIDLAKSDIFTEEQQWTTE---TLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYAEVPGN----TTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRK-----------------DGHYFGELAS-------YAEGLVLK-------------NRKSSKDLLANI----NRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCL---YLPVLIFPIIYFVPDEQHERQAAEREHQKSLNQKSSKVKSHKEKNDAPVV-PVYRSKEEKAVSNDEEARVGTENEEEDFQLEDYIPEIREDDSMEVIMRNKKLGFCDRIMHFYSAPFSKFVGNVVGYLAFIFLYAYVVLFNFPRFDPAKTLGGIHPTEIVLYFWVFTILIEEIRQ--LAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEIQGEKPKEFGEVDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVWRMCRCGHPPRGST--MKIGLSPAEMEQMDNWEFQAAEMYIHQQQ 1177
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Nematostella
Match: EDO47658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLT7]) HSP 1 Score: 311.997 bits (798), Expect = 1.280e-88 Identity = 317/1151 (27.54%), Postives = 539/1151 (46.83%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGK--NPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFT-------VLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVS------KEADCSVVQLIVEGGKNTIQTGAEALK--SNIPVVVMKGSKRAADVICD----VVESSSDM--FQDTIKLK--LEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKI-FW-KC--GKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVN-IFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFS--EHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNF-ISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV---DTSYMEGS-QCLFGYCATP------NAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDA---FIANLIHEEDLECSGFEQQCMETYL 3459
+G ++ G AG+ KY+R+ D + +L+ W PKL+IS+ GGAKN I L+ K + GL+ +++ W++TGG TGV + VGEA K ++++S+ + ++GI +WG +KE L + P + + LD H FIL D+G+D ++G EI FR E ++ K VV L++EGG NTI+T E++ +PVV+ +GS RAAD++ + S+ +M D ++ + L + EK + + E++ + +N++ +C + V +F + D +D AI+ A +K Q E +L LA+ ++RAD+A+ IF + +K E+ + L M AL+ ++ +FVD L G+++ +FLT L +LY K + + H + D+ S +M N+ T ++ Q C + + I + Y PV P + ++ S+ +Y + + + + + +++ L I + W C G+ L + + Q+ + + + M EF +A+ +L E Y+ + + LLI YWG + L +A ++ F+ HS CQ +L IW+G + N ++L+ + F L IF + + Q V T + + + L DF HR+ S + Y + + F K +K +E E + + R +G I FY APITKF N+I YL FL +FS+ +LIEL + IE + I ++ L E + V NF + ++W S++WN D ++F +A LR +N ++S+ + ++ IR ++ + V + +GP V+MI RM D+++FL I ++ L AYG ++L+P+ + L+ IF+ PY+Q++G++ D Y S + F +TP +V V AF+LL N+LLL+LLIA+F TF +V+ NSN++W F R+ ++ E+ RP L PPF + + K I K + S A F L EE + FE+QC ET+L
Sbjct: 20 FGELEFQG----AGQPSRAKYIRLAHDTD--PELVLRLLCGEWALDLPKLLISVTGGAKNFI-LSPKIKRVLREGLLKAAQTTGAWVITGGTNTGVMRHVGEAVKGHTVMSRGEQLKNTAHQVHLIGIASWGIVDHKEMLVNPKVE---VVPYQMTSSMQSRGACLDNNHSHFILVDNGTDGEYGGEISFRASLENLIASKKMAQKFHGVPVVLLVLEGGPNTIRTVLESVSRCPAVPVVIAEGSGRAADILAFAHRFIAPSNGEMSGVADVVEHRQLLHKIEKSFAECSPEDRLSIYQNVL---KCVAKREFVTIFCVDDGGLEVDKAILRA----LLKSQHSQLEDQLSLALVWDRADIAKTEIF-TEDQKWEVPM-LETAMMEALLHDRVEFVDLLLDNGVSMANFLTVKRLEELYRKVRGSKANHASSRIFMHYHNDTYTNASTQM-----NKHTHGIYTQR------------CTHLHYARTHTYLHGHAHAHIRFCTY--PVPLSPLQSMGSVLLFTSEKMPSRVTRYGFF---STSLRFVKQSTEIYHPPLPPLSISYLQTEAWDPCVRGEPQEAQMLQICIKPGNRQETSAKEAAADASCRDMLDSREFYDIALGLLDECYKANDVLAQRLLIYHPVYWGGRTSLSLAVASRHEEFVAHSCCQKKLTEIWMGALKTGYNGSLKVLLGILFPPL-----IFALEFRSREEMQRVPTTDDDSADD-LPPDFDPYHHREPGSAQ-YNDGYLGDGVAFVKNRKSSGNEE-----EPIVEIRL--------LGLGKRIIGFYNAPITKFWSNLIVYLLFLVVFSHVILIELPPVP--------SIEEWVLIGFVFSLCAEEVRQVRVINVWNFSFFESSDWASNVWNLCDGFAMVLFFLAVGLR--LNPGTLRIGHLVYSLDIMLWIIRLLDIFSVSKDLGPYVVMIGRMTIDMMYFLVIMVVFLLAYGVAQQAILFPHEKPSWELITKIFFRPYFQVYGELFIEDVDYSSNSRETAF---STPKFDEYGGRLVTVIMAFYLLVANILLLNLLIAIFNNTFSEVQANSNQIWKFQRFSLVMEYRQRPRLVPPFILIAHAHGLAK-AIWKRACGAPASRQADCKFKLFLGKEEYHKLMLFEEQCTETFL 1095
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Medaka
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:101156483]) HSP 1 Score: 321.627 bits (823), Expect = 6.170e-90 Identity = 309/1219 (25.35%), Postives = 564/1219 (46.27%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDM--FQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNMK-DFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEA----------NSDSCSCCCWKSP-----KISDSQSFNDSSCEVIDYEKYIEPVAT-EPTTNCCCCFKINGDEESSKEMKYTVYPIRN-KNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNA-IVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAEIKDELKSLNEKVYKIRRLQKKTV 3666
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++ S K+ T+ GI WG N+ L + I P + L+ H F+L DDG+ K+G E+K R + E+ ++ + VV LI EGG N I T E L+ +PVVV +G+ RAAD++ V + + + D ++ + +K +N + + FQ + EC + + + +F++ + + ++D AI++A GT P +L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT + L +LY +++ N L V + + + K +L +G +I L + Y S+ S P K ++ S E + +I+ +P + E++ K K + I + + ++ Y +L +WA+L +R +M+ FW+ G++++ ALVA +C S+ +A ++ ++ ++ Y +F TLA+++L +++R+D+ LL L W +CL +A + L F+ H+ Q L+++W+G++ N +++++++ + I + Y K + + S+ ++ +D SEH N+QN + K D T K E H ++ I FY API KF N + YL FL +++Y +L+++ +P+ E+ + ++ + + +I + FM + K W S +N D + F I LR D+ F+ R ++ +++ +Y+R ++ V Q GP V+MI++M+ ++ + + I L+ L +YG ++LYPN + L R++ + PYW ++G+V D + CA+ + A +L +L+++LLIA F +M+V+ SN VW F RY I ++ +P+LPPPF + Y+ F C + S L E+ + FE+QC+ETY D H S+ + +T++ A+ +K + + IK L +L+ ++ ++ L TV
Sbjct: 110 YGVINFQGGSHSYRA------KYVRLSYD--SRPESVLRLMLKEWHMELPKILISVHGGVQNF-ELHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHCSRSAKKICTI-GIAPWGVIENRNDLIGKD----IIAPYQTLLNPLSKLNVLNNLHSHFLLVDDGTVGKYGAEVKLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQETPPVPVVVCEGTGRAADILAYVHKQTEEGGGLPDGVETDIIATIKKTFNFSHSDAIHLFQ----MLMECMKSKELITVFDISSEEQQDIDVAILKALLQGT-NSSPFD---QLVLTLAWDRVDIAKNHVF---VYGQQLLVSSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTINRLEELYNTKQSPNNPTLLHLVRDVKQSNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGSNRRSGRHAAGPGSHFRKSHEAFSMQADKKEKTRHNHFIKTAQPYKPKVDSSA-------EQNKKRSKEEIVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEENMAKALVACKLCRSMGYEAKKSDVVDDTSDKLKDYSNDFGTLAVDLLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSHLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSI---LVPPAILLLEY----KSKAEMAHIPQSQDDHQMTMED-SEH-----------NFQNLHEDIQMDVFKEARSHDHVET----KHDMEMHVRSRKLPLTRKIYAFYHAPIVKFWSNTLFYLGFLMLYTYVVLVKM---IQAPSTQ----EWVVIVYIFTSAIEKIREMFMS-EAGKISQKIKVWFSDYFNVSDFLAIVTFFIGCGLRLAGGDA-FLPGRIVYCLNIIFWYVRLLDILAVNQQAGPYVMMIAKMVANMFYIVVIMLVVLLSYGVPRKAILYPNEEPSWTLARDVVFQPYWMMYGEVYAYEIDVCANNSEDSVKPLCASAGVWLTPFLQAVYLFVQYILMVNLLIAFFNNVYMQVKSISNLVWKFQRYHFIMAYHEKPVLPPPFILLCHVYSLF----CMCRKRKKESTYGPKLFLTEEDQKKLHDFEEQCVETYFHEK---DDQFHSGSEERIR----LTSQRVE-AMSLQLKEVGNKVNFIKRSLHTLDSQIGHLQDLSALTV 1252
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Medaka
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:101156483]) HSP 1 Score: 321.627 bits (823), Expect = 6.890e-90 Identity = 309/1219 (25.35%), Postives = 565/1219 (46.35%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDM--FQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNMK-DFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEA----------NSDSCSCCCWKSP-----KISDSQSFNDSSCEVIDYEKYIEPVAT-EPTTNCCCCFKINGDEESSKEMKYTVYPIRN-KNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNA-IVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAEIKDELKSLNEKVYKIRRLQKKTV 3666
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++ S K+ T+ GI WG N+ L + I P + L+ H F+L DDG+ K+G E+K R + E+ ++ + VV LI EGG N I T E L+ +PVVV +G+ RAAD++ V + + + D ++ + +K +N + + FQ + EC + + + +F++ + + ++D AI++A GT P +L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT + L +LY +++ N L V + + + K +L +G +I L + Y S+ S P K ++ S E + +I+ +P + + E++ K K + I + + ++ Y +L +WA+L +R +M+ FW+ G++++ ALVA +C S+ +A ++ ++ ++ Y +F TLA+++L +++R+D+ LL L W +CL +A + L F+ H+ Q L+++W+G++ N +++++++ + I + Y K + + S+ ++ +D SEH N+QN + K D T K E H ++ I FY API KF N + YL FL +++Y +L+++ +P+ E+ + ++ + + +I + FM + K W S +N D + F I LR D+ F+ R ++ +++ +Y+R ++ V Q GP V+MI++M+ ++ + + I L+ L +YG ++LYPN + L R++ + PYW ++G+V D + CA+ + A +L +L+++LLIA F +M+V+ SN VW F RY I ++ +P+LPPPF + Y+ F C + S L E+ + FE+QC+ETY D H S+ + +T++ A+ +K + + IK L +L+ ++ ++ L TV
Sbjct: 102 YGVINFQGGSHSYRA------KYVRLSYD--SRPESVLRLMLKEWHMELPKILISVHGGVQN-FELHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHCSRSAKKICTI-GIAPWGVIENRNDLIGKD----IIAPYQTLLNPLSKLNVLNNLHSHFLLVDDGTVGKYGAEVKLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQETPPVPVVVCEGTGRAADILAYVHKQTEEGGGLPDGVETDIIATIKKTFNFSHSDAIHLFQ----MLMECMKSKELITVFDISSEEQQDIDVAILKALLQGT-NSSPFD---QLVLTLAWDRVDIAKNHVF---VYGQQLLVSSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTINRLEELYNTKQSPNNPTLLHLVRDVKQSNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGSNRRSGRHAAGPGSHFRKSHEAFSMQADKKEKTRHNHFIKTAQPYKPKVD-------SSAEQNKKRSKEEIVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEENMAKALVACKLCRSMGYEAKKSDVVDDTSDKLKDYSNDFGTLAVDLLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSHLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSI---LVPPAILLLEY----KSKAEMAHIPQSQDDHQMTMED-SEH-----------NFQNLHEDIQMDVFKEARSHDHVET----KHDMEMHVRSRKLPLTRKIYAFYHAPIVKFWSNTLFYLGFLMLYTYVVLVKM---IQAPSTQ----EWVVIVYIFTSAIEKIREMFMS-EAGKISQKIKVWFSDYFNVSDFLAIVTFFIGCGLRLAGGDA-FLPGRIVYCLNIIFWYVRLLDILAVNQQAGPYVMMIAKMVANMFYIVVIMLVVLLSYGVPRKAILYPNEEPSWTLARDVVFQPYWMMYGEVYAYEIDVCANNSEDSVKPLCASAGVWLTPFLQAVYLFVQYILMVNLLIAFFNNVYMQVKSISNLVWKFQRYHFIMAYHEKPVLPPPFILLCHVYSLF----CMCRKRKKESTYGPKLFLTEEDQKKLHDFEEQCVETYFHEK---DDQFHSGSEERIR----LTSQRVE-AMSLQLKEVGNKVNFIKRSLHTLDSQIGHLQDLSALTV 1244
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Medaka
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:101156483]) HSP 1 Score: 321.242 bits (822), Expect = 8.834e-90 Identity = 309/1219 (25.35%), Postives = 564/1219 (46.27%), Query Frame = 1
Query: 148 YGAIQLSG----YRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKE-------ADCSVVQLIVEGGKNTIQTGAEALKSN--IPVVVMKGSKRAADVICDVVESSSDM--FQDTIKLKL-EEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK-VHLFNMK-DFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININ-LRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKA--NAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEA----------NSDSCSCCCWKSP-----KISDSQSFNDSSCEVIDYEKYIEPVAT-EPTTNCCCCFKINGDEESSKEMKYTVYPIRN-KNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMR-YQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNI-FQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV-----DTSYMEGSQCLFGYCATPNA-IVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAEIKDELKSLNEKVYKIRRLQKKTV 3666
YG I G YR KYVR+ D + + +LM W + PK++IS++GG +N L+ K +GLI + + WI+TGG TGV+K VG+A K++ S K+ T+ GI WG N+ L + I P + L+ H F+L DDG+ K+G E+K R + E+ ++ + VV LI EGG N I T E L+ +PVVV +G+ RAAD++ V + + + D ++ + +K +N + + FQ + EC + + + +F++ + + ++D AI++A GT P +L L + ++R D+A+ +F V ++ ++ L M AL+ ++ FV + G+++ FLT + L +LY +++ N L V + + + K +L +G +I L + Y S+ S P K ++ S E + +I+ +P + E++ K K + I + + ++ Y +L +WA+L +R +M+ FW+ G++++ ALVA +C S+ +A ++ ++ ++ Y +F TLA+++L +++R+D+ LL L W +CL +A + L F+ H+ Q L+++W+G++ N +++++++ + I + Y K + + S+ ++ +D SEH N+QN + K D T K E H ++ I FY API KF N + YL FL +++Y +L+++ +P+ E+ + ++ + + +I + FM + K W S +N D + F I LR D+ F+ R ++ +++ +Y+R ++ V Q GP V+MI++M+ ++ + + I L+ L +YG ++LYPN + L R++ + PYW ++G+V D + CA+ + A +L +L+++LLIA F +M+V+ SN VW F RY I ++ +P+LPPPF + Y+ F C + S L E+ + FE+QC+ETY D H S+ + +T++ A+ +K + + IK L +L+ ++ ++ L TV
Sbjct: 95 YGVINFQGGSHSYRA------KYVRLSYD--SRPESVLRLMLKEWHMELPKILISVHGGVQNF-ELHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHCSRSAKKICTI-GIAPWGVIENRNDLIGKD----IIAPYQTLLNPLSKLNVLNNLHSHFLLVDDGTVGKYGAEVKLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQETPPVPVVVCEGTGRAADILAYVHKQTEEGGGLPDGVETDIIATIKKTFNFSHSDAIHLFQ----MLMECMKSKELITVFDISSEEQQDIDVAILKALLQGT-NSSPFD---QLVLTLAWDRVDIAKNHVF---VYGQQLLVSSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTINRLEELYNTKQSPNNPTLLHLVRDVKQSNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGSNRRSGRHAAGPGSHFRKSHEAFSMQADKKEKTRHNHFIKTAQPYKPKVDSSA-------EQNKKRSKEEIVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEENMAKALVACKLCRSMGYEAKKSDVVDDTSDKLKDYSNDFGTLAVDLLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSHLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSI---LVPPAILLLEY----KSKAEMAHIPQSQDDHQMTMED-SEH-----------NFQNLHEDIQMDVFKEARSHDHVET----KHDMEMHVRSRKLPLTRKIYAFYHAPIVKFWSNTLFYLGFLMLYTYVVLVKM---IQAPSTQ----EWVVIVYIFTSAIEKIREMFMS-EAGKISQKIKVWFSDYFNVSDFLAIVTFFIGCGLRLAGGDA-FLPGRIVYCLNIIFWYVRLLDILAVNQQAGPYVMMIAKMVANMFYIVVIMLVVLLSYGVPRKAILYPNEEPSWTLARDVVFQPYWMMYGEVYAYEIDVCANNSEDSVKPLCASAGVWLTPFLQAVYLFVQYILMVNLLIAFFNNVYMQVKSISNLVWKFQRYHFIMAYHEKPVLPPPFILLCHVYSLF----CMCRKRKKESTYGPKLFLTEEDQKKLHDFEEQCVETYFHEK---DDQFHSGSEERIR----LTSQRVE-AMSLQLKEVGNKVNFIKRSLHTLDSQIGHLQDLSALTV 1237
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060]) HSP 1 Score: 215.698 bits (548), Expect = 2.083e-56 Identity = 197/696 (28.30%), Postives = 317/696 (45.55%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQ-TFTVLGIGTWGATYNKEKLAMQTEDDRITYPN-YDPQKVGKGQ-SPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVS----KEADCS----VVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFY--ECYQIGKV-HLFNM----KDFKNNLDTAIIEAAFSGTIKDQPLGDEA---KLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTN-SMLRDLY-------FKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPF 2148
+G IQ G + K Y RV + S LY L+T W P L+IS+ GGAKN L + F RGLI V+++ WI+TGG GV K VG+A +DYS+ + Q +G+ TWG +N+E L ++ +P Y K +G+ S LD H F+L DDG+ +G EI+ RT E+ +S + D S VV +++EGG T+ T A+K+ P V+ +G+ R ADVI V S + Q TI L + EK + +E F + VI + + I ++ HL + +D ++D AI++A + + L + +L LA+ +NR D+A+ IF + + +L M +AL+ N+ QFV L G+++ FL N L +LY F K +H+ + + I + L+ T +++P ++ C + +S S S N NG + E+ R+ + D+FLWA+L ++A+I W+ +D I +AL AT + L+K AG + + E + +E AI + SE Y D+ R LL+ +WG + L +A K + F+ S Q + +W G++ +I ++LI + F
Sbjct: 93 FGEIQFDGLQQTTAK---YARVSSETS--PEVLYDLLTEQWHLLPPNLLISVTGGAKNF-NLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRDYSLSNSIQGQIVAIGVATWGVIHNREALI----NEEGCFPALYMTDKTSQGRLSCLDKNHTHFLLVDDGTHGHYGVEIELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIAQV--SGLPLQQITITLIHQLMEKFFG----QEYKKFTELSVIEWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTEDSLWS--SADLHQAMFSALVGNKPQFVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHSKADLVDSNNITLTHVSD--EVRHLLGNATRHIYPPYVEQRY-------CMSAEDLSLSLSKN------------------------------NGAPRPAGEVAQ-----RDAS-------SDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRI---LKKLAGGESDAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLF 716 HSP 2 Score: 108.612 bits (270), Expect = 2.470e-23 Identity = 92/306 (30.07%), Postives = 150/306 (49.02%), Query Frame = 1
Query: 2458 FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYC-RTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFG-----------QVDTSYMEGSQCLFGYCAT---------PNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVF 3312
Y +P KF NI+SY FL +F+ L+++ + P E +Y++ S + E Q F F K + + +WN D+ ++F + R T S+ Y + + I +F +R M + + Q++GPK+I++ RM+KD+ FF+ + I + AYG +L N + R Y PY +FG +D+ M G+ L C P + +LLF N+LLL+LLIA+F TF +V++N++R+W F RY +I+E++ RP PPPF +F
Sbjct: 776 LYGSPQVKFYWNIVSYFFFLNLFAGVLMMDFHATPSVP-------ELLLYVWVFSLVCEEFRQLFCNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFRLT---SELFYAGKIVLCIDFVVFCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQGILIHNDTRLDWIFRGAIYEPYLIIFGNFPENLAEAKFSLDSCSMNGTDPLKPKCPILNENHAPVFPEWLTITMLCVYLLFANILLLNLLIAIFNFTFQEVQDNTDRIWKFQRYELIKEYHSRPAAPPPFIIF 1071
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060]) HSP 1 Score: 215.312 bits (547), Expect = 3.237e-56 Identity = 197/696 (28.30%), Postives = 317/696 (45.55%), Query Frame = 1
Query: 148 YGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQ-TFTVLGIGTWGATYNKEKLAMQTEDDRITYPN-YDPQKVGKGQ-SPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVS----KEADCS----VVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFY--ECYQIGKV-HLFNM----KDFKNNLDTAIIEAAFSGTIKDQPLGDEA---KLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTN-SMLRDLY-------FKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPF 2148
+G IQ G + K Y RV + S LY L+T W P L+IS+ GGAKN L + F RGLI V+++ WI+TGG GV K VG+A +DYS+ + Q +G+ TWG +N+E L ++ +P Y K +G+ S LD H F+L DDG+ +G EI+ RT E+ +S + D S VV +++EGG T+ T A+K+ P V+ +G+ R ADVI V S + Q TI L + EK + +E F + VI + + I ++ HL + +D ++D AI++A + + L + +L LA+ +NR D+A+ IF + + +L M +AL+ N+ QFV L G+++ FL N L +LY F K +H+ + + I + L+ T +++P ++ C + +S S S N NG + E+ R+ + D+FLWA+L ++A+I W+ +D I +AL AT + L+K AG + + E + +E AI + SE Y D+ R LL+ +WG + L +A K + F+ S Q + +W G++ +I ++LI + F
Sbjct: 93 FGEIQFDGLQQTTAK---YARVSSETS--PEVLYDLLTEQWHLLPPNLLISVTGGAKNF-NLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRDYSLSNSIQGQIVAIGVATWGVIHNREALI----NEEGCFPALYMTDKTSQGRLSCLDKNHTHFLLVDDGTHGHYGVEIELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIAQV--SGLPLQQITITLIHQLMEKFFG----QEYKKFTELSVIEWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTEDSLWS--SADLHQAMFSALVGNKPQFVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHSKADLVDSNNITLTHVSD--EVRHLLGNATRHIYPPYVEQRY-------CMSAEDLSLSLSKN------------------------------NGAPRPAGEVAQ-----RDAS-------SDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRI---LKKLAGGESDAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLF 716 HSP 2 Score: 108.612 bits (270), Expect = 2.374e-23 Identity = 92/306 (30.07%), Postives = 150/306 (49.02%), Query Frame = 1
Query: 2458 FYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYC-RTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFG-----------QVDTSYMEGSQCLFGYCAT---------PNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVF 3312
Y +P KF NI+SY FL +F+ L+++ + P E +Y++ S + E Q F F K + + +WN D+ ++F + R T S+ Y + + I +F +R M + + Q++GPK+I++ RM+KD+ FF+ + I + AYG +L N + R Y PY +FG +D+ M G+ L C P + +LLF N+LLL+LLIA+F TF +V++N++R+W F RY +I+E++ RP PPPF +F
Sbjct: 776 LYGSPQVKFYWNIVSYFFFLNLFAGVLMMDFHATPSVP-------ELLLYVWVFSLVCEEFRQLFCNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFRLT---SELFYAGKIVLCIDFVVFCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQGILIHNDTRLDWIFRGAIYEPYLIIFGNFPENLAEAKFSLDSCSMNGTDPLKPKCPILNENHAPVFPEWLTITMLCVYLLFANILLLNLLIAIFNFTFQEVQDNTDRIWKFQRYELIKEYHSRPAAPPPFIIF 1071
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Planmine SMEST
Match: SMESG000035341.1 (SMESG000035341.1) HSP 1 Score: 2399.78 bits (6218), Expect = 0.000e+0 Identity = 1199/1199 (100.00%), Postives = 1199/1199 (100.00%), Query Frame = 1
Query: 85 MESHPSVESDCSEFWRHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAEIKDELKSLNEKVYKIRRLQKKTVISGNN 3681
MESHPSVESDCSEFWRHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFKKIKKKLKIKEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDILFFLAIYLIALFAYGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCATPNAIVQVANAFFLLFTNVLLLSLLIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAEIKDELKSLNEKVYKIRRLQKKTVISGNN
Sbjct: 1 MESHPSVESDCSEFWRHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFKKIKKKLKIKEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDILFFLAIYLIALFAYGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVDTSYMEGSQCLFGYCATPNAIVQVANAFFLLFTNVLLLSLLIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKLNICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQLLDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAEIKDELKSLNEKVYKIRRLQKKTVISGNN 1199
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Planmine SMEST
Match: SMESG000004955.1 (SMESG000004955.1) HSP 1 Score: 431.409 bits (1108), Expect = 8.578e-132 Identity = 343/1172 (29.27%), Postives = 589/1172 (50.26%), Query Frame = 1
Query: 148 YGAIQLSGYRVIA-GKNPKYVRVHKDLSNIKGEL----YKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILS--KKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCC-CCFKINGDEESSKEMKYTVYPIRNKNKQIIY--TEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKN-FISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVD-TSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKL----NICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQL------LDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAE 3597
+G I+ GY I+ NP+++R N EL Y+L+T W F KP+L+IS+NGG K M NN QK FK+GL++V + +TWI+ GGF G+ KLV EA D+ ILS + ++ I TWG N L + T Y N + + KG+ LDP +D ++ DDG+++++ +EI FR +FE +V ++ VQ++ EGGK I++ +L+ +IP+VV+K S RAAD+IC+++E+ D + +++ + +E TD++K + L Y Y+ E + DQ + + K+ A+ +R D ++ VR N ++I DF + Q + ++ +YFKE + + H + E + +NL S C C + ISD D S ++ + P N +KI + S +K+ + +R+ N + ++LFLW+L++ EMA IFW+ GK+++GSAL+ +++ S ++ +KG ++ + ++ +F+ LA +I+++AY+ +Q +TH++L R L W +CL IA L++FL +AC++ W+G + F+ ++IL+ +PF L + FI PY +N + + L + + EKI + N + + K K H D+V FC A+ FY API KFV+ ++SY+ FL +F+Y L+EL I + E +YIF + F++ EI Q + KN I K ++ S WN +D+ +F I+ I+R TVN FI+ R ++++LS+F +R M+FY++ +S+GPKVIMI +M+ D+ FFL+I+ + + +YGT S S+ PN L+ +FY PY+Q +G++ + S C C +A + + FLL TN+LLL+LLIAMFG TF K++ S + ++F + ++++EF+ +P++PPP N+ +Y KL I + ++ R + I L +++L+ GFE CME+ ++ N ++L++ + T K+ + I + +N + + + + +G I +
Sbjct: 21 FGKIKFLGYEDISLNTNPQFIRFFPTDGNNFQELTYNAYELITKYWNFPKPQLLISINGGFKRMNFKNNQQKKNFKQGLMEVMRKDTTWIIGGGFHVGIHKLVSEAVNDFRILSDENENQVKLISISTWGVVKNNRSLTVGT----CAYDNSNT--IEKGKVTLDPNYDCYLFCDDGTEKEYDKEIDFRLDFERNV-RDIGAFAVQILYEGGKRAIESIYRSLQKSIPLVVIKESGRAADLICEILET------DKMNVEIVDKYEEQLRLTDDDKIRIIEILSDIYSNYK---------------------ERITIHDLLDQNVHLDKKILDAIISSREDRNLEKTLNLAVRFNCVDI-----------------ADFKVFQSSRASTLSQKTL--GIYFKEMLSKNQHEMLQLFLVNNFSIDE------------FVQENLQDLYMTSLRSIKCRC----TEMISDLILREDKSFKIDN--------INNPGKNLLKVIYKIICNL-SDNILKFESFNLRSSNSHNANQNSYRELFLWSLISGYTEMALIFWENGKENVGSALIGSIILSKMKSYIKSKGFNDMSDTLLKTSIKFQELACDIITKAYKINQEKTHIVLTRPLNLWNNLTCLQIAIGGNLLDFLNLNACRSYTREAWMGDLSPFLPTWKILVTIPFSPLLIKPFIIPY------------VSNKKSCSNLSHEKVKDKFLFEKEKI-ELNIRKKS----------------------PKSWKSYHSESDQVSFCRALIKFYRAPIVKFVIYLLSYITFLVIFAYLNLVELKPIKEVKVIQNVTAELLVYIFILGFIVEEINQ--INNTEKNGLIYKLKSYVSGSWNLYDMLTIFIFIISIIMRFTVNGDSFIFVRCFYAVTLSLFSLRTMQFYFISRSIGPKVIMIRKMIVDVFFFLSIFSLFIISYGTLSHSIQNPNSKWNLFLISELFYRPYFQTYGELMLDDFKIPSPCNTTVCIVQSATLIIGFGIFLLMTNILLLNLLIAMFGYTFNKIQGESEKFFSFIQIQLVDEFHNKPLMPPPLNI--AYYILRKLWQSGKIIFHGDSKRKNT-FLIKYLNDDQNLKIRGFEHLCMESAMLENHQSTNVANINLNSDNLFDTILKNLELINEKLNNKSSDKAITSRLGVIEK 1074
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Planmine SMEST
Match: SMESG000004955.1 (SMESG000004955.1) HSP 1 Score: 431.795 bits (1109), Expect = 8.794e-132 Identity = 343/1172 (29.27%), Postives = 589/1172 (50.26%), Query Frame = 1
Query: 148 YGAIQLSGYRVIA-GKNPKYVRVHKDLSNIKGEL----YKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILS--KKQTFTVLGIGTWGATYNKEKLAMQTEDDRITYPNYDPQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLYFKEKANAHLHTAVNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCC-CCFKINGDEESSKEMKYTVYPIRNKNKQIIY--TEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKN-FISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQVD-TSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEFYYRPILPPPFNVFEVFYNFFKL----NICKNSNNGRLSVDAFIANLIHEEDLECSGFEQQCMETYLITNQL------LDLSAHDASKTWFKSDDSITNEPSNVAIEAHVKALVGSIAE 3597
+G I+ GY I+ NP+++R N EL Y+L+T W F KP+L+IS+NGG K M NN QK FK+GL++V + +TWI+ GGF G+ KLV EA D+ ILS + ++ I TWG N L + T Y N + + KG+ LDP +D ++ DDG+++++ +EI FR +FE +V ++ VQ++ EGGK I++ +L+ +IP+VV+K S RAAD+IC+++E+ D + +++ + +E TD++K + L Y Y+ E + DQ + + K+ A+ +R D ++ VR N ++I DF + Q + ++ +YFKE + + H + E + +NL S C C + ISD D S ++ + P N +KI + S +K+ + +R+ N + ++LFLW+L++ EMA IFW+ GK+++GSAL+ +++ S ++ +KG ++ + ++ +F+ LA +I+++AY+ +Q +TH++L R L W +CL IA L++FL +AC++ W+G + F+ ++IL+ +PF L + FI PY +N + + L + + EKI + N + + K K H D+V FC A+ FY API KFV+ ++SY+ FL +F+Y L+EL I + E +YIF + F++ EI Q + KN I K ++ S WN +D+ +F I+ I+R TVN FI+ R ++++LS+F +R M+FY++ +S+GPKVIMI +M+ D+ FFL+I+ + + +YGT S S+ PN L+ +FY PY+Q +G++ + S C C +A + + FLL TN+LLL+LLIAMFG TF K++ S + ++F + ++++EF+ +P++PPP N+ +Y KL I + ++ R + I L +++L+ GFE CME+ ++ N ++L++ + T K+ + I + +N + + + + +G I +
Sbjct: 36 FGKIKFLGYEDISLNTNPQFIRFFPTDGNNFQELTYNAYELITKYWNFPKPQLLISINGGFKRMNFKNNQQKKNFKQGLMEVMRKDTTWIIGGGFHVGIHKLVSEAVNDFRILSDENENQVKLISISTWGVVKNNRSLTVGT----CAYDNSNT--IEKGKVTLDPNYDCYLFCDDGTEKEYDKEIDFRLDFERNV-RDIGAFAVQILYEGGKRAIESIYRSLQKSIPLVVIKESGRAADLICEILET------DKMNVEIVDKYEEQLRLTDDDKIRIIEILSDIYSNYK---------------------ERITIHDLLDQNVHLDKKILDAIISSREDRNLEKTLNLAVRFNCVDI-----------------ADFKVFQSSRASTLSQKTL--GIYFKEMLSKNQHEMLQLFLVNNFSIDE------------FVQENLQDLYMTSLRSIKCRC----TEMISDLILREDKSFKIDN--------INNPGKNLLKVIYKIICNL-SDNILKFESFNLRSSNSHNANQNSYRELFLWSLISGYTEMALIFWENGKENVGSALIGSIILSKMKSYIKSKGFNDMSDTLLKTSIKFQELACDIITKAYKINQEKTHIVLTRPLNLWNNLTCLQIAIGGNLLDFLNLNACRSYTREAWMGDLSPFLPTWKILVTIPFSPLLIKPFIIPY------------VSNKKSCSNLSHEKVKDKFLFEKEKI-ELNIRKKS----------------------PKSWKSYHSESDQVSFCRALIKFYRAPIVKFVIYLLSYITFLVIFAYLNLVELKPIKEVKVIQNVTAELLVYIFILGFIVEEINQ--INNTEKNGLIYKLKSYVSGSWNLYDMLTIFIFIISIIMRFTVNGDSFIFVRCFYAVTLSLFSLRTMQFYFISRSIGPKVIMIRKMIVDVFFFLSIFSLFIISYGTLSHSIQNPNSKWNLFLISELFYRPYFQTYGELMLDDFKIPSPCNTTVCIVQSATLIIGFGIFLLMTNILLLNLLIAMFGYTFNKIQGESEKFFSFIQIQLVDEFHNKPLMPPPLNI--AYYILRKLWQSGKIIFHGDSKRKNT-FLIKYLNDDQNLKIRGFEHLCMESAMLENHQSTNVANINLNSDNLFDTILKNLELINEKLNNKSSDKAITSRLGVIEK 1089
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Planmine SMEST
Match: SMESG000004977.1 (SMESG000004977.1) HSP 1 Score: 398.667 bits (1023), Expect = 1.095e-119 Identity = 325/1057 (30.75%), Postives = 522/1057 (49.39%), Query Frame = 1
Query: 148 YGAIQLSGYR-VIAGKNPKYVRVH-KDLSNIKGELYKLMTNVWGFKKPKLIISLNGGAKNMIPLNNDQKLAFKRGLIDVSKSASTWIVTGGFETGVSKLVGEASKDYSILSKKQTFTV--LGIGTWGATYNKEKLAMQTEDDRITYPNYD-PQKVGKGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGKVHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLY---FKEKANAHLHTAVNFIF--KGTIDSPEKQS---LKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQ--VDTSYMEGSQCLFGYCATPNAIVQVANAXXXXXXXXXXXXXXIAMFGVTFMKVEENSNRVWAFTRYRMIEEF 3273
+G I +GY +I P ++R + +D I +YKLM W F KP+LIIS+ GG K M N QK FK+ LI+V K TWI+ GGF G+ L+ EA +Y + V LGI TWGA N + L + P Y +K KG+ LD + D F+ DDG+++++ +E FR +FE+ V + + +VVQ++ EGG +++ +LK++IP+V++K S RAADVI +++ + + IK L + NI +++ FQ+ L YE Y+ ++ + ++ D LD I+EA S +I D L E L + + FN D+AE+++F N ++ L + L NQ +FV FL ++E FLT L LY K + + V+FI DS K+S L + R+IN ++ N+ E + +P I DEE+ + + + +K T QDLFLWALLT+ E+A IFWK G++HIGSAL+A+++ + ++ +G + R ++F+ +AI +++EA+ + Q T+ LLIR L W +CL IA L+ FL SAC + + IW G++ F+ +++ILI++PF ++ + I P Q Q+ S E + +F Y+ N+ FKR + S+ +K+ + + I+ FY PI KFV+++ISY+ FL +F Y L+EL L+ +R E I+ + + + EI Q + + I K + S WN +D+ +V+ I + LR ++ FI R +S++LSM +R M++Y++ ++GPKVIMI RM+ DI FFL I L + +M+L L+ IFY PY+Q +G+ +D + + A FLL TN+LL++LLIAMFG TF K++ S++ ++F + +++EEF
Sbjct: 58 FGIINFTGYNDIITNHYPHFIRFNCEDAPEIVEVVYKLMILYWNFFKPQLIISVTGGLKRMNFNTNQQKKNFKQSLIEVLKKDKTWIIGGGFNVGIHNLISEAVYEYRSQQANSSNQVKLLGICTWGAILNNKILCNEN-------PTYHFTKKTEKGKVLLDSHCDGFLFCDDGTEKQYDKETNFRLKFEKCVRENDNGNVVQILYEGGSRALESAYNSLKASIPLVLIKNSGRAADVINAILDLKMTSYLEKIKSILSANQSTMNI-DEKDIEKFQEILREIYEKYR-NQIFVHDLFDKSMKLDRKIVEAVIS-SIDDNDL--EKILKITIKFNCFDIAEKKVFLNADYQSLNQKILHENFKLVLKNNQIEFVKLFLENNFSIEDFLTEEDLNGLYNHSLYVKPSRCGYLLVDFIATTDKNFDSKRKKSKYLLYPVRRIINMMSGNILQN----------------------------------------ENIHPKPGRQL-----IRTDEENFEFQSQSFIEVHSKK----ITPQDLFLWALLTEFTELAIIFWKIGEEHIGSALIASIILNKMEGLIRKRGYSDTSAMLSRASKKFQEMAIAVVTEAHNKRQESTYTLLIRTLKTWNNMTCLQIAISGNLLEFLSQSACDSYIRKIWRGELSPFLPMWKILISIPFSFILIKPLIMP------SVNQPTQSERSNESAESQTPEFM--------------YEANS--------------PFKR--HYSQSKKKA-----SIPYKDMIKMFYQVPIVKFVIHLISYVLFLLVFIYLNLVELK---LNLKIQNRWAEIFIFFYVLGIITEEIRQ-IIDQERTGSIYKLKAYLSGSWNIYDICGILVYIITFFLRCFLSQDLFIVTRCFYSVTLSMNCLRIMQYYFISPTLGPKVIMIGRMIVDIFFFLTIALQDNRSR---AMNL---------SLITEIFYRPYFQTYGELMLDEFHTNDENITDIDRTIGRMTIICGFAVFLLLTNILLINLLIAMFGHTFNKIQVESHKFFSFIQLQLVEEF 996
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Planmine SMEST
Match: SMESG000005064.1 (SMESG000005064.1) HSP 1 Score: 318.546 bits (815), Expect = 1.849e-90 Identity = 230/833 (27.61%), Postives = 418/833 (50.18%), Query Frame = 1
Query: 601 KGQSPLDPYHDAFILYDDGSDRKFGREIKFRTEFEESVSKEADCSVVQLIVEGGKNTIQTGAEALKSNIPVVVMKGSKRAADVICDVVESSSDMFQDTIKLKLEEFEKEWNITTDEEKGNFQKNLVIFYECYQIGK--VHLFNMKDFKNNLDTAIIEAAFSGTIKDQPLGDEAKLWLAMTFNRADVAEQRIFENQVRKNEININLRPFMETALIRNQWQFVDFFLRQGLTVESFLTNSMLRDLY----------FKEKANAHLHTA-VNFIFKGTIDSPEKQSLKMIGRLINQLTDNLFPQMYQEANSDSCSCCCWKSPKISDSQSFNDSSCEVIDYEKYIEPVATEPTTNCCCCFKINGDEESSKEMKYTVYPIRNKNKQIIYTEQDLFLWALLTQRIEMAKIFWKCGKDHIGSALVATVVCSSLQKKAGAKGEIEIMNNWMRYQEEFETLAINILSEAYRRDQIRTHLLLIRALPYWGRESCLDIANKNQLINFLFHSACQTRLNNIWLGKIPNFVNIFQILINVPFGYLTSRIFIFPYNLLGKRQTQAVQTNNSEPGTELLSKDFSEHRQKSSEKIIQPNYQNNTLQFXXXXXXXXXXEDFKRTEYLSKFRKEQHESLDEVGFCSAIRFFYTAPITKFVMNIISYLAFLTMFSYFLLIELNTITLSPTAYSRKIEYCIYIFYISFLLGEIYQFFMGGQVKNFISKFNNWKSSMWNWFDLGIYIVFTIAYILRNTVNDSDFIYCRTLFSISLSMFYIRFMEFYYVQQSVGPKVIMISRMLKDXXXXXXXXXXXXXXXGTFSMSLLYPNINITSPLMRNIFYNPYWQLFGQV 3060
KG+ LD HD F+ DDG+++++ RE++FR +FE + + D +VQ++ EGG+ ++ L IP+V++KGS A++I V+E + ++ I + E + + ++ KG + + E Y+ K + +++M + D I+EA G + L + L L + F +A + +F + + + L N+ +F++ F+ VE F+ + +LRDLY E + +A + K + + L +IG+++ +L+ N+ +Y++ +K + ND+ + +N DE S E Y +N + Q+LFLWALL+ EM+ +FWK KD IGSAL+A+ + S+ +G+ + + ++++ L++ IL+EAY++++++T++LLIR L W +CL IA + ++ FL HSAC++ + +W+G++ ++ ++I++ +PF ++ + I P + P +++ D S+ S K+++ K E + ++ ES +++ + A+R FY A I KF + ++SY++FL +F Y L+EL + + E IYI+ +F+ EI Q ++ I+K + S +WN D+ I +F ++ ILR ++ ++F+ CR F+++LSMF+IR M+FY++ QS+GPKVIMI ML+DILFFL+I++I L AYGT SL +PN L ++I Y PY+Q FG++
Sbjct: 431 KGKHTLDGLHDNFLFCDDGTEKQYDREVEFRLKFENYLKNKTDAFLVQILFEGGRMAMEHVYTVLNDEIPIVIVKGSGGIANLIASVMELPNSKHKENISALVNENQHLF----EKSKGEITEYINFLCEIYRKYKRQIVIYDMMNNNMKFDKKILEAMILGY--NNSL--DKTLKLCIRFKCPKIANRAVFSDSKYQKISRKTIEKMFINCLKENRPEFIELFIENNFEVEKFINDEILRDLYQISFNPDQCQCAELLSELCRSARTTYFTKKNENEIDLDILYIIGKVVQKLSGNVIKNLYEK----------YKFSTEKNKLVLNDAEIQ------------------------LNNDETSFNEDFY------EENGLLSLNAQNLFLWALLSGMTEMSLVFWKINKDQIGSALLASTILRSMASLMLKRGDNNLEKKFSETSKKYQDLSVLILTEAYKKNKMKTYILLIRELKKWNNTTCLQIATNSDMLEFLNHSACRSYITKVWMGELSPILSNWKIILTIPFSFIFIKPLIIP----------------TFPPKKIMH-DESDKMDSSEMKLLE-----------------------KTEEVQYSYPVKRIES-EKISYREAMRVFYGATIVKFYIYLLSYVSFLLIFIYLNLVELKPLEDVKSIKDVLAEIYIYIYVFTFICEEIRQV-TDQKITGLINKAKEYFSGIWNKIDVFIISLFFLSVILRFSIPKTNFMSCRCCFAVTLSMFFIRAMQFYFINQSIGPKVIMIREMLRDILFFLSIFIIFLLAYGTLFQSLKFPNSKFDLNLFKDIVYLPYFQTFGEL 1173 The following BLAST results are available for this feature:
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30029075 ID=SMED30029075|Name=Transient receptor potential cation channel subfamily M member 2|organism=Schmidtea mediterranea sexual|type=transcript|length=3710bpback to top protein sequence of SMED30029075-orf-1 >SMED30029075-orf-1 ID=SMED30029075-orf-1|Name=SMED30029075-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1200bp MESHPSVESDCSEFWRHEKFQYGAIQLSGYRVIAGKNPKYVRVHKDLSNIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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