Endophilin-B1

Overview
NameEndophilin-B1
Smed IDSMED30029068
Length (bp)1076
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Endophilin-B1 (SMED30029068) t-SNE clustered cells

Violin plots show distribution of expression levels for Endophilin-B1 (SMED30029068) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Endophilin-B1 (SMED30029068) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Endophilin-B1 (SMED30029068) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029068

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30029068SMESG000051256.1 dd_Smed_v4_5645_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30029068SMESG000051256.1 dd_Smed_v4_5645_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30029068SMESG000051256.1 dd_Smed_v4_5645_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Endophilin-B1 vs. Ensembl Human
Match: SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1 [Source:HGNC Symbol;Acc:HGNC:10833])

HSP 1 Score: 164.081 bits (414), Expect = 1.431e-46
Identity = 101/276 (36.59%), Postives = 157/276 (56.88%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRS-------EAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S       E   + +   E  ++ ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:   10 KLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMIWAEE--VTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 276
[Close]
BLAST of Endophilin-B1 vs. Ensembl Human
Match: SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1 [Source:HGNC Symbol;Acc:HGNC:10833])

HSP 1 Score: 161.77 bits (408), Expect = 7.860e-46
Identity = 99/273 (36.26%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S                ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS----------------SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. Ensembl Human
Match: SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1 [Source:HGNC Symbol;Acc:HGNC:10833])

HSP 1 Score: 160.614 bits (405), Expect = 4.309e-45
Identity = 101/287 (35.19%), Postives = 160/287 (55.75%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSD--------------TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S+    A L  + ++ +              ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNS-ARLEGDNIMVNFSYMLNFLHVKWLKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 284
[Close]
BLAST of Endophilin-B1 vs. Ensembl Human
Match: SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2 [Source:HGNC Symbol;Acc:HGNC:10834])

HSP 1 Score: 120.553 bits (301), Expect = 2.659e-30
Identity = 89/277 (32.13%), Postives = 146/277 (52.71%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSD----TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  S+A    +R VQ+TEEK    EKT  DA  E L+ + D  +  TEKI++  E  +QPNP+ R+E  +YEKLD K    ++   ++   M   + +L        P + Y   L    E+  ++G A ++ ++     F+ PL+++LE   K + KER+ L+ +RLDLDA K +LK+    E+K +            L +D     +++L+  Q EF++Q EVT LL+E + ++   H R L +FV  +  YY  C+  +  LQ+ L +F
Sbjct:    3 FNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELG-------PTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKAT------------LWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRF 260
[Close]
BLAST of Endophilin-B1 vs. Ensembl Human
Match: SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2 [Source:HGNC Symbol;Acc:HGNC:10834])

HSP 1 Score: 119.783 bits (299), Expect = 6.395e-30
Identity = 90/286 (31.47%), Postives = 148/286 (51.75%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEK---------LLSD----TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  S+A    +R VQ+TEEK    EKT  DA  E L+ + D  +  TEKI++  E  +QPNP+ R+E  +YEKLD K    ++   ++   M   + +L        P + Y   L    E+  ++G A ++ ++     F+ PL+++LE   K + KER+ L+ +RLDLDA K +LK+    E+K +   +     P           L +D     +++L+  Q EF++Q EVT LL+E + ++   H R L +FV  +  YY  C+  +  LQ+ L +F
Sbjct:    3 FNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELG-------PTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRF 281
[Close]
BLAST of Endophilin-B1 vs. Ensembl Celegans
Match: F35A5.8 (pep chromosome:WBcel235:X:3800737:3802771:-1 gene:WBGene00001335.1 transcript:F35A5.8b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F35A5.8)

HSP 1 Score: 120.939 bits (302), Expect = 1.149e-31
Identity = 83/271 (30.63%), Postives = 141/271 (52.03%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKR-SEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESL 905
             +  K  S+A    SR  Q TEE     E+T  D+  E L+ + D  +  T +++ +IE ++QPNP  R+E + YEKL+ K+       +I  + +  +S  +     Q    + Y  AL    ++ N++G A +EL  +  T  + P++ +LE  +K +QKERK L  KRLDLDA K++LK+  T + +  + +K       E+     + D++  Q EF++Q E+T LL+E +  +     + L DFV+ +  +Y   H+ +  LQ  L
Sbjct:    3 FNFKKIASDAGGFFSRAKQLTEETFLKAERTELDSHFENLLQRADKTEDHTRRLLSAIEGYLQPNPTVRMEEVFYEKLELKK-----DGAIRQNNLEQLSTAMTEAGEQFGETTPYGSALLKVAQTENRLGQAERELCGQAATNTLLPIRRFLEGDMKTIQKERKVLNSKRLDLDACKSRLKKAKTVDLQTVTNSKTSGGFTIEQ----AEADVRVAQAEFDKQSEITKLLLEGIQTAHNNQLKCLRDFVEAQMSFYAQSHQLMADLQREL 264
[Close]
BLAST of Endophilin-B1 vs. Ensembl Celegans
Match: F35A5.8 (pep chromosome:WBcel235:X:3800045:3802771:-1 gene:WBGene00001335.1 transcript:F35A5.8a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F35A5.8)

HSP 1 Score: 120.168 bits (300), Expect = 9.271e-31
Identity = 83/267 (31.09%), Postives = 140/267 (52.43%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKR-SEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESL 905
            K  S+A    SR  Q TEE     E+T  D+  E L+ + D  +  T +++ +IE ++QPNP  R+E + YEKL+ K+       +I  + +  +S  +     Q    + Y  AL    ++ N++G A +EL  +  T  + P++ +LE  +K +QKERK L  KRLDLDA K++LK+  T + +  + +K       E+     + D++  Q EF++Q E+T LL+E +  +     + L DFV+ +  +Y   H+ +  LQ  L
Sbjct:    7 KIASDAGGFFSRAKQLTEETFLKAERTELDSHFENLLQRADKTEDHTRRLLSAIEGYLQPNPTVRMEEVFYEKLELKK-----DGAIRQNNLEQLSTAMTEAGEQFGETTPYGSALLKVAQTENRLGQAERELCGQAATNTLLPIRRFLEGDMKTIQKERKVLNSKRLDLDACKSRLKKAKTVDLQTVTNSKTSGGFTIEQ----AEADVRVAQAEFDKQSEITKLLLEGIQTAHNNQLKCLRDFVEAQMSFYAQSHQLMADLQREL 264
[Close]
BLAST of Endophilin-B1 vs. Ensembl Celegans
Match: F35A5.8 (pep chromosome:WBcel235:X:3800045:3802767:-1 gene:WBGene00001335.1 transcript:F35A5.8c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F35A5.8)

HSP 1 Score: 119.783 bits (299), Expect = 1.238e-30
Identity = 82/266 (30.83%), Postives = 136/266 (51.13%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESL 905
            K  S+A    SR  Q TEE     E+T  D+  E L+ + D  +  T +++ +IE ++QPNP  R+E + YEKL+ K+       +I  + +  +S  +     Q    + Y  AL    ++ N++G A +EL  +  T  + P++ +LE  +K +QKERK L  KRLDLDA K++LK+  T +                L +  + D++  Q EF++Q E+T LL+E +  +     + L DFV+ +  +Y   H+ +  LQ  L
Sbjct:    7 KIASDAGGFFSRAKQLTEETFLKAERTELDSHFENLLQRADKTEDHTRRLLSAIEGYLQPNPTVRMEEVFYEKLELKK-----DGAIRQNNLEQLSTAMTEAGEQFGETTPYGSALLKVAQTENRLGQAERELCGQAATNTLLPIRRFLEGDMKTIQKERKVLNSKRLDLDACKSRLKKAKTVD----------------LQTVAEADVRVAQAEFDKQSEITKLLLEGIQTAHNNQLKCLRDFVEAQMSFYAQSHQLMADLQREL 251
[Close]
BLAST of Endophilin-B1 vs. Ensembl Celegans
Match: unc-57 (Endophilin-A homolog [Source:UniProtKB/Swiss-Prot;Acc:B1V8A0])

HSP 1 Score: 55.0694 bits (131), Expect = 3.080e-8
Identity = 57/249 (22.89%), Postives = 110/249 (44.18%), Query Frame = 3 
Query:  117 ISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLE---SMVYEKLDGKRIVHISPAS--IVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE--QVKNVQKERKELEGKRLDLDAIKTKLKR---VVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEV---TNLLMENVVASLGYHTR 824
            +S      ++  QY  E +   E T  D     +    D    L   +V     ++QPNPA R +    +   K+ G       P +  ++ D M    Q L  N       S+   +L  + E++ ++     ++ +  +  F++PL ++L+  ++K+V   R +L+G+RLD D  K + +R   ++  E K  E+K +A +    +LS+    +  ++   E QL+    T   +EN+   LG+  +
Sbjct:    3 LSGLRKQFNKANQYLSETMGAAEPTKLDDVFNEMEKNVDTTYNLITDLVAGTNEYLQPNPATRAKMATQVALSKVRGTTKTSPYPQTEGMLADVMQKYGQQLGDN-------SDLGKSLNDAAETYRQMADIKYQMEDNVKQNFLDPL-THLQNNELKDVNHHRTKLKGRRLDYDCKKRQQRRDDEMIQAEEKLEESKRLAEMSMFNVLSNDVEQISQLRALIEAQLDFHRQTAQCLENLQQQLGHRIK 243
[Close]
BLAST of Endophilin-B1 vs. Ensembl Celegans
Match: unc-57 (Endophilin-A homolog [Source:UniProtKB/Swiss-Prot;Acc:B1V8A0])

HSP 1 Score: 55.0694 bits (131), Expect = 3.153e-8
Identity = 57/249 (22.89%), Postives = 110/249 (44.18%), Query Frame = 3 
Query:  117 ISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLE---SMVYEKLDGKRIVHISPAS--IVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE--QVKNVQKERKELEGKRLDLDAIKTKLKR---VVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEV---TNLLMENVVASLGYHTR 824
            +S      ++  QY  E +   E T  D     +    D    L   +V     ++QPNPA R +    +   K+ G       P +  ++ D M    Q L  N       S+   +L  + E++ ++     ++ +  +  F++PL ++L+  ++K+V   R +L+G+RLD D  K + +R   ++  E K  E+K +A +    +LS+    +  ++   E QL+    T   +EN+   LG+  +
Sbjct:    3 LSGLRKQFNKANQYLSETMGAAEPTKLDDVFNEMEKNVDTTYNLITDLVAGTNEYLQPNPATRAKMATQVALSKVRGTTKTSPYPQTEGMLADVMQKYGQQLGDN-------SDLGKSLNDAAETYRQMADIKYQMEDNVKQNFLDPL-THLQNNELKDVNHHRTKLKGRRLDYDCKKRQQRRDDEMIQAEEKLEESKRLAEMSMFNVLSNDVEQISQLRALIEAQLDFHRQTAQCLENLQQQLGHRIK 243
[Close]
BLAST of Endophilin-B1 vs. Ensembl Fly
Match: EndoB (gene:FBgn0034433 transcript:FBtr0113097)

HSP 1 Score: 135.191 bits (339), Expect = 4.936e-36
Identity = 90/267 (33.71%), Postives = 143/267 (53.56%), Query Frame = 3 
Query:  114 FISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKK 911
             +  A S +SRVVQ TEEKL   E+T YD   + L  + D+ +  TEKIV+  ES + PNP  R+E  ++EK++  +   +S    +   MI    D      Q  P   Y  AL   G++  K+G    + +  +   F +PL+ +L+ ++K + KER  LE KRLDLDA K ++K+  +   ++S+      + PE +L   +RDL+  Q EF++Q E+T LL++ +  S   H R L  F+  +  YY+ C + + +LQ  L K
Sbjct:   13 LVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIPNPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDF----GQDLP---YGQALIKVGQAEQKLGQCEHDFIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSKDG----ISPEAVLEQAERDLRVAQAEFDRQAEITKLLLDGISTSQASHLRHLHAFIQTQVRYYKQCGDVMEQLQRELAK 268
[Close]
BLAST of Endophilin-B1 vs. Ensembl Fly
Match: EndoB (gene:FBgn0034433 transcript:FBtr0086558)

HSP 1 Score: 135.191 bits (339), Expect = 6.870e-36
Identity = 83/244 (34.02%), Postives = 131/244 (53.69%), Query Frame = 3 
Query:  114 FISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFV 842
             +  A S +SRVVQ TEEKL   E+T YD   + L  + D+ +  TEKIV+  ES + PNP  R+E  ++EK++  +   +S    +   MI    D      Q  P   Y  AL   G++  K+G    + +  +   F +PL+ +L+ ++K + KER  LE KRLDLDA K ++K+  +   ++S+      + PE +L   +RDL+  Q EF++Q E+T LL++ +  S   H R L  F+
Sbjct:   13 LVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIPNPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDF----GQDLP---YGQALIKVGQAEQKLGQCEHDFIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSKDG----ISPEAVLEQAERDLRVAQAEFDRQAEITKLLLDGISTSQASHLRHLHAFI 245
[Close]
BLAST of Endophilin-B1 vs. Ensembl Fly
Match: EndoB (gene:FBgn0034433 transcript:FBtr0113098)

HSP 1 Score: 125.561 bits (314), Expect = 1.488e-32
Identity = 87/267 (32.58%), Postives = 137/267 (51.31%), Query Frame = 3 
Query:  114 FISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKK 911
             +  A S +SRVVQ TEEKL   E+T YD   + L  + D+ +  TEKIV+  ES + PNP  R+E  ++EK++  +   +S    +   MI    D      Q  P   Y  AL   G++  K+G    + +  +   F +PL+ +L+ ++K + KER  LE KRLDLDA K ++K+  +   ++S                 +RDL+  Q EF++Q E+T LL++ +  S   H R L  F+  +  YY+ C + + +LQ  L K
Sbjct:   13 LVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIPNPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDF----GQDLP---YGQALIKVGQAEQKLGQCEHDFIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQS----------------AERDLRVAQAEFDRQAEITKLLLDGISTSQASHLRHLHAFIQTQVRYYKQCGDVMEQLQRELAK 256
[Close]
BLAST of Endophilin-B1 vs. Ensembl Fly
Match: EndoB (gene:FBgn0034433 transcript:FBtr0086559)

HSP 1 Score: 125.176 bits (313), Expect = 2.130e-32
Identity = 80/244 (32.79%), Postives = 125/244 (51.23%), Query Frame = 3 
Query:  114 FISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFV 842
             +  A S +SRVVQ TEEKL   E+T YD   + L  + D+ +  TEKIV+  ES + PNP  R+E  ++EK++  +   +S    +   MI    D      Q  P   Y  AL   G++  K+G    + +  +   F +PL+ +L+ ++K + KER  LE KRLDLDA K ++K+  +   ++S                 +RDL+  Q EF++Q E+T LL++ +  S   H R L  F+
Sbjct:   13 LVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIPNPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDF----GQDLP---YGQALIKVGQAEQKLGQCEHDFIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQS----------------AERDLRVAQAEFDRQAEITKLLLDGISTSQASHLRHLHAFI 233
[Close]
BLAST of Endophilin-B1 vs. Ensembl Fly
Match: EndoA (gene:FBgn0038659 transcript:FBtr0083699)

HSP 1 Score: 58.5362 bits (140), Expect = 2.643e-9
Identity = 61/263 (23.19%), Postives = 116/263 (44.11%), Query Frame = 3 
Query:  138 VSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYE---KLDG--KRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSY-LEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLK 908
            +++  QY  EK+   E T  D     +  +TD+   L E++    + F+QPNP  R +    +   KL G  K   +  P  ++ + M++  + L       E  S ++ AL   GE+  ++      L +  +  F+EPL     + +K V   RK+L+G+RLD D              +R +AK              D +++  + +F + L++  + M N++ +   H   L  F +   +++  C + +  LQE+L+
Sbjct:   10 INKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTARAKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLG------EDNSVFAQALVEFGEALKQMADVKYSLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDC------------KRRRQAK--------------DDEIRGAEDKFGESLQLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQ 240
[Close]
BLAST of Endophilin-B1 vs. Ensembl Zebrafish
Match: sh3glb1a (SH3-domain GRB2-like endophilin B1a [Source:ZFIN;Acc:ZDB-GENE-050417-89])

HSP 1 Score: 144.821 bits (364), Expect = 1.122e-39
Identity = 98/269 (36.43%), Postives = 152/269 (56.51%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            +F ++A +  SR VQ+TEEK    EKT  DA  E L+ + +  +  TEKI+K  E  +QPNP  R+E ++YEKLD K    ++   ++G +MI          N+  P + Y  AL   GE+  +IG A +E +  +   F+ P +++LE   K + KERK L+ KRLDLDA KTK      +++K ++A+ VA           ++DLK  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    7 RFAADAGTLFSRAVQFTEEKFGQAEKTELDAHLETLLTRAECTKHWTEKILKQTEVLLQPNPNARIEELLYEKLDKKAPPRMNNHELMGQSMIDSG-------NEFGPGTAYGNALIKCGETEKQIGGAEREFIQTSAINFLTPFRNFLEGDFKTILKERKLLQNKRLDLDAAKTK-----LKKAKMADARAVA-----------EQDLKMTQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMVDLQKQLGNF 252
[Close]
BLAST of Endophilin-B1 vs. Ensembl Zebrafish
Match: sh3glb1a (SH3-domain GRB2-like endophilin B1a [Source:ZFIN;Acc:ZDB-GENE-050417-89])

HSP 1 Score: 144.821 bits (364), Expect = 1.122e-39
Identity = 98/269 (36.43%), Postives = 152/269 (56.51%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            +F ++A +  SR VQ+TEEK    EKT  DA  E L+ + +  +  TEKI+K  E  +QPNP  R+E ++YEKLD K    ++   ++G +MI          N+  P + Y  AL   GE+  +IG A +E +  +   F+ P +++LE   K + KERK L+ KRLDLDA KTK      +++K ++A+ VA           ++DLK  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    7 RFAADAGTLFSRAVQFTEEKFGQAEKTELDAHLETLLTRAECTKHWTEKILKQTEVLLQPNPNARIEELLYEKLDKKAPPRMNNHELMGQSMIDSG-------NEFGPGTAYGNALIKCGETEKQIGGAEREFIQTSAINFLTPFRNFLEGDFKTILKERKLLQNKRLDLDAAKTK-----LKKAKMADARAVA-----------EQDLKMTQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMVDLQKQLGNF 252
[Close]
BLAST of Endophilin-B1 vs. Ensembl Zebrafish
Match: sh3glb1b (SH3-domain GRB2-like endophilin B1b [Source:ZFIN;Acc:ZDB-GENE-030131-6851])

HSP 1 Score: 140.198 bits (352), Expect = 5.771e-38
Identity = 89/269 (33.09%), Postives = 142/269 (52.79%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            +  ++A + +SR VQ+TEEK    EKT  DA  E L+ + +  +  TEKI+K  E  +QPNP  R+E  +YE LD K     +   ++G  MI    +         P + Y  AL   GE+   +G A +E ++ +   F+ P ++++E   K + KERK L+ KRLDLDA K ++K+    +++                S  + +L+  Q EF++Q E+T LL+E + ++  +H R L DFVD +A YY  C++    LQ+ L  F
Sbjct:    7 RLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLEMLLSRAESTKHWTEKIMKQTEVVLQPNPNVRVEEFLYEILDKKVPTRANNHEMLGQCMIDSGHEFG-------PGTAYGSALIKCGETEKLLGSAEKEFIHSSAINFLTPFRNFIEGDFKTILKERKLLQNKRLDLDAAKNRMKKARVADAR----------------SAAETELRIAQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVDAQAAYYAQCYQYTVNLQKQLGSF 252
[Close]
BLAST of Endophilin-B1 vs. Ensembl Zebrafish
Match: sh3glb1b (SH3-domain GRB2-like endophilin B1b [Source:ZFIN;Acc:ZDB-GENE-030131-6851])

HSP 1 Score: 139.043 bits (349), Expect = 2.652e-37
Identity = 93/285 (32.63%), Postives = 149/285 (52.28%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPP---------EKLLS-------DTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            +  ++A + +SR VQ+TEEK    EKT  DA  E L+ + +  +  TEKI+K  E  +QPNP  R+E  +YE LD K     +   ++G  MI    +         P + Y  AL   GE+   +G A +E ++ +   F+ P ++++E   K + KERK L+ KRLDLDA K ++K+    +++   + E+   PP           +LS         + +L+  Q EF++Q E+T LL+E + ++  +H R L DFVD +A YY  C++    LQ+ L  F
Sbjct:    7 RLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLEMLLSRAESTKHWTEKIMKQTEVVLQPNPNVRVEEFLYEILDKKVPTRANNHEMLGQCMIDSGHEFG-------PGTAYGSALIKCGETEKLLGSAEKEFIHSSAINFLTPFRNFIEGDFKTILKERKLLQNKRLDLDAAKNRMKKARVADAR---SAELNCSPPLGEEYVAHFSYMLSFLHVRWLKAETELRIAQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVDAQAAYYAQCYQYTVNLQKQLGSF 281
[Close]
BLAST of Endophilin-B1 vs. Ensembl Zebrafish
Match: sh3glb1b (SH3-domain GRB2-like endophilin B1b [Source:ZFIN;Acc:ZDB-GENE-030131-6851])

HSP 1 Score: 137.887 bits (346), Expect = 5.072e-37
Identity = 88/266 (33.08%), Postives = 141/266 (53.01%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESL 905
            +  ++A + +SR VQ+TEEK    EKT  DA  E L+ + +  +  TEKI+K  E  +QPNP  R+E  +YE LD K     +   ++G  MI    +         P + Y  AL   GE+   +G A +E ++ +   F+ P ++++E   K + KERK L+ KRLDLDA K ++K+    +++                S  + +L+  Q EF++Q E+T LL+E + ++  +H R L DFVD +A YY  C++    LQ+ L
Sbjct:    7 RLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLEMLLSRAESTKHWTEKIMKQTEVVLQPNPNVRVEEFLYEILDKKVPTRANNHEMLGQCMIDSGHEFG-------PGTAYGSALIKCGETEKLLGSAEKEFIHSSAINFLTPFRNFIEGDFKTILKERKLLQNKRLDLDAAKNRMKKARVADAR----------------SAAETELRIAQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVDAQAAYYAQCYQYTVNLQKQL 249
[Close]
BLAST of Endophilin-B1 vs. Ensembl Xenopus
Match: sh3glb1 (SH3 domain GRB2 like, endophilin B1 [Source:NCBI gene;Acc:548826])

HSP 1 Score: 159.073 bits (401), Expect = 9.838e-45
Identity = 96/277 (34.66%), Postives = 160/277 (57.76%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSD----TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEK    EKT  DA  E L+ + +  ++ TEKI+K  E  +QPNP  R+E  VYEKLD K     +P+ +  +T   ++Q +    N+  P + Y  AL   GE+  +IG+AH+EL+      F+ PL++++E   K + KE+K L+ KRLDLDA KT+LK+    E+ R+    V      ++ ++     +++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  Y+   ++ +  LQ+ L  F
Sbjct:    3 FNVKKLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRK-----APSRL--NTEEQLAQYMTDAGNEFGPGTAYGNALIKCGETQKRIGVAHRELVQTAAINFLTPLRNFIEGDFKTMSKEKKLLQNKRLDLDAAKTRLKKARVTEA-RAAVTYVFSFNANQMWTEEVTKAEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYFAQSYQYMLDLQKQLGSF 271
[Close]
BLAST of Endophilin-B1 vs. Ensembl Xenopus
Match: sh3glb1 (SH3 domain GRB2 like, endophilin B1 [Source:NCBI gene;Acc:548826])

HSP 1 Score: 158.303 bits (399), Expect = 1.541e-44
Identity = 96/273 (35.16%), Postives = 158/273 (57.88%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEK    EKT  DA  E L+ + +  ++ TEKI+K  E  +QPNP  R+E  VYEKLD K     +P+ +  +T   ++Q +    N+  P + Y  AL   GE+  +IG+AH+EL+      F+ PL++++E   K + KE+K L+ KRLDLDA KT+LK+     ++ +EA+  A           +++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  Y+   ++ +  LQ+ L  F
Sbjct:    3 FNVKKLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRK-----APSRL--NTEEQLAQYMTDAGNEFGPGTAYGNALIKCGETQKRIGVAHRELVQTAAINFLTPLRNFIEGDFKTMSKEKKLLQNKRLDLDAAKTRLKK-----ARVTEARAAA-----------EQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYFAQSYQYMLDLQKQLGSF 252
[Close]
BLAST of Endophilin-B1 vs. Ensembl Xenopus
Match: sh3glb1 (SH3 domain GRB2 like, endophilin B1 [Source:NCBI gene;Acc:548826])

HSP 1 Score: 154.451 bits (389), Expect = 8.746e-43
Identity = 98/298 (32.89%), Postives = 165/298 (55.37%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPE---------------------KLLSD----TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEK    EKT  DA  E L+ + +  ++ TEKI+K  E  +QPNP  R+E  VYEKLD K     +P+ +  +T   ++Q +    N+  P + Y  AL   GE+  +IG+AH+EL+      F+ PL++++E   K + KE+K L+ KRLDLDA KT+LK+    E++   A ++++  PE                     K+ ++     +++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  Y+   ++ +  LQ+ L  F
Sbjct:    3 FNVKKLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRK-----APSRL--NTEEQLAQYMTDAGNEFGPGTAYGNALIKCGETQKRIGVAHRELVQTAAINFLTPLRNFIEGDFKTMSKEKKLLQNKRLDLDAAKTRLKKARVTEAR---AAQLSVTQPEGDNNFMVNLSYMMSVLHIKWLKMWTEEVTKAEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYFAQSYQYMLDLQKQLGSF 290
[Close]
BLAST of Endophilin-B1 vs. Ensembl Xenopus
Match: sh3glb1 (SH3 domain GRB2 like, endophilin B1 [Source:NCBI gene;Acc:548826])

HSP 1 Score: 147.132 bits (370), Expect = 1.667e-40
Identity = 91/255 (35.69%), Postives = 147/255 (57.65%), Query Frame = 3 
Query:  153 QYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            Q+TEEK    EKT  DA  E L+ + +  ++ TEKI+K  E  +QPNP  R+E  VYEKLD K     +P+ +  +T   ++Q +    N+  P + Y  AL   GE+  +IG+AH+EL+      F+ PL++++E   K + KE+K L+ KRLDLDA KT+LK+     ++ +EA+  A           +++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  Y+   ++ +  LQ+ L  F
Sbjct:    8 QFTEEKFGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRK-----APSRL--NTEEQLAQYMTDAGNEFGPGTAYGNALIKCGETQKRIGVAHRELVQTAAINFLTPLRNFIEGDFKTMSKEKKLLQNKRLDLDAAKTRLKK-----ARVTEARAAA-----------EQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYFAQSYQYMLDLQKQLGSF 239
[Close]
BLAST of Endophilin-B1 vs. Ensembl Xenopus
Match: sh3glb1 (SH3 domain GRB2 like, endophilin B1 [Source:NCBI gene;Acc:548826])

HSP 1 Score: 145.591 bits (366), Expect = 6.384e-40
Identity = 90/255 (35.29%), Postives = 147/255 (57.65%), Query Frame = 3 
Query:  153 QYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            ++TEEK    EKT  DA  E L+ + +  ++ TEKI+K  E  +QPNP  R+E  VYEKLD K     +P+ +  +T   ++Q +    N+  P + Y  AL   GE+  +IG+AH+EL+      F+ PL++++E   K + KE+K L+ KRLDLDA KT+LK+     ++ +EA+  A           +++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  Y+   ++ +  LQ+ L  F
Sbjct:    3 KFTEEKFGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRK-----APSRL--NTEEQLAQYMTDAGNEFGPGTAYGNALIKCGETQKRIGVAHRELVQTAAINFLTPLRNFIEGDFKTMSKEKKLLQNKRLDLDAAKTRLKK-----ARVTEARAAA-----------EQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYFAQSYQYMLDLQKQLGSF 234
[Close]
BLAST of Endophilin-B1 vs. Ensembl Mouse
Match: Sh3glb1 (SH3-domain GRB2-like B1 (endophilin) [Source:MGI Symbol;Acc:MGI:1859730])

HSP 1 Score: 166.007 bits (419), Expect = 2.402e-47
Identity = 102/280 (36.43%), Postives = 159/280 (56.79%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESK-------RSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E+K       R E   + +   E  ++ ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSARPEGDNIMIWAEE--VTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 276
[Close]
BLAST of Endophilin-B1 vs. Ensembl Mouse
Match: Sh3glb1 (SH3-domain GRB2-like B1 (endophilin) [Source:MGI Symbol;Acc:MGI:1859730])

HSP 1 Score: 162.925 bits (411), Expect = 1.431e-46
Identity = 100/273 (36.63%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E+K                S ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETK----------------SSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. Ensembl Mouse
Match: Sh3glb1 (SH3-domain GRB2-like B1 (endophilin) [Source:MGI Symbol;Acc:MGI:1859730])

HSP 1 Score: 162.925 bits (411), Expect = 2.229e-46
Identity = 100/273 (36.63%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E+K                S ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETK----------------SSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. Ensembl Mouse
Match: Sh3glb1 (SH3-domain GRB2-like B1 (endophilin) [Source:MGI Symbol;Acc:MGI:1859730])

HSP 1 Score: 159.844 bits (403), Expect = 6.028e-45
Identity = 102/286 (35.66%), Postives = 159/286 (55.59%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEV------AMLPPEKLLS-------DTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E+K S+           M+    +L+        ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSARPEGDNIMVNFSYMLNFLHVKWLKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 284
[Close]
BLAST of Endophilin-B1 vs. Ensembl Mouse
Match: Sh3glb2 (SH3-domain GRB2-like endophilin B2 [Source:MGI Symbol;Acc:MGI:2385131])

HSP 1 Score: 119.398 bits (298), Expect = 3.903e-30
Identity = 88/277 (31.77%), Postives = 146/277 (52.71%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSD----TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  S+A    +R VQ+TEEK    EKT  DA  E L+ + D  +  TE+I++  E  +QPNP+ R+E  +YEKLD K    ++   ++   M   + +L        P + Y   L    E+  ++G A ++ ++     F+ PL+++LE   K + KER+ L+ +RLDLDA K +LK+    E+K +            L +D     +++L+  Q EF++Q EVT LL+E + ++   H R L +FV  +  YY  C+  +  LQ+ L +F
Sbjct:    3 FNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELG-------PSTPYGKTLIKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKAT------------LWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRF 260
[Close]
BLAST of Endophilin-B1 vs. UniProt/SwissProt
Match: sp|Q9JK48|SHLB1_MOUSE (Endophilin-B1 OS=Mus musculus OX=10090 GN=Sh3glb1 PE=1 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 1.559e-45
Identity = 100/273 (36.63%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E+K                S ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETK----------------SSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. UniProt/SwissProt
Match: sp|Q6AYE2|SHLB1_RAT (Endophilin-B1 OS=Rattus norvegicus OX=10116 GN=Sh3glb1 PE=2 SV=1)

HSP 1 Score: 162.155 bits (409), Expect = 2.782e-45
Identity = 99/273 (36.26%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  ++ TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E+K                S ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETK----------------SSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. UniProt/SwissProt
Match: sp|Q5R8P5|SHLB1_PONAB (Endophilin-B1 OS=Pongo abelii OX=9601 GN=SH3GLB1 PE=2 SV=2)

HSP 1 Score: 161.77 bits (408), Expect = 3.775e-45
Identity = 99/273 (36.26%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S                ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS----------------SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. UniProt/SwissProt
Match: sp|Q9Y371|SHLB1_HUMAN (Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1)

HSP 1 Score: 161.77 bits (408), Expect = 3.775e-45
Identity = 99/273 (36.26%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S                ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNS----------------SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. UniProt/SwissProt
Match: sp|Q32LM0|SHLB1_BOVIN (Endophilin-B1 OS=Bos taurus OX=9913 GN=SH3GLB1 PE=2 SV=1)

HSP 1 Score: 161.77 bits (408), Expect = 4.063e-45
Identity = 99/273 (36.26%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S                ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRAS----------------SEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. TrEMBL
Match: K1Q963 (Endophilin-B1 OS=Crassostrea gigas OX=29159 GN=CGI_10012647 PE=4 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 1.375e-46
Identity = 105/283 (37.10%), Postives = 165/283 (58.30%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRV-VTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF----*IGNWCSHS 941
            KF+S+AS+  +R VQ+TEEKL + EKT  DA  E L+ + D  +  TEKI+K  ES +QPNP  R+E  VYEKLD K+   ++   ++G  ++    D         P + Y  AL   G++  +IG A +E +  T   F++PL ++LE  +K +QKE+K LE KRLDLDA K +L++   T + + S+     +L    ++ + + DL+  Q EF++Q E+T LL+E V ++  +H R L DF++ +  YY  C   I++LQ+ L  +     +GN  S+S
Sbjct:   12 KFVSDASTVFNRAVQFTEEKLGSAEKTELDAHFENLLQRADKTKAWTEKILKQTESVLQPNPNIRMEDFVYEKLDKKKRDRVNHHEVLGHVLVDGGNDFG-------PGTTYGNALVKCGQAQLRIGNAEREFIQTTSNNFLQPLHNFLEGDMKTIQKEKKILETKRLDLDASKNRLRKAKSTSQPQSSQNSPQNVL----MMVEAEADLRVAQAEFDRQAEITKLLLEGVSSAHAHHLRCLNDFIEAQLTYYAQCQNYISELQQQLGSYSHTSGVGNNSSNS 283
[Close]
BLAST of Endophilin-B1 vs. TrEMBL
Match: A0A4D9EDM2 (Growth factor receptor-bound protein 2 OS=Platysternon megacephalum OX=55544 GN=DR999_PMT11681 PE=4 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 2.227e-44
Identity = 100/273 (36.63%), Postives = 153/273 (56.04%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
             ++ KF ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  ++ TEKI+K  E  +QPNP  R+E  VYEKLD K    ++   ++G  MI          N+  P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ +  +EV +                 Q EF++Q E+T LL+E + ++  +H R L DFVD +  YY  C++ +  LQ+ L  F
Sbjct:    6 FNVKKFAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKLWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRMNNPELLGQYMIDAG-------NEFGPGTAYGNALIKCGETQKRIGTADRELIQTSAINFLTPLRNFIEGDYKTITKERKLLQNKRLDLDAAKTRLKKAKVAEARAASEQEVRI----------------TQSEFDRQAEITRLLLEGISSTHAHHLRCLTDFVDAQMTYYAQCYQYMLDLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. TrEMBL
Match: A0A3Q7PCI8 (endophilin-B1 isoform X3 OS=Callorhinus ursinus OX=34884 GN=SH3GLB1 PE=4 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 2.232e-44
Identity = 104/283 (36.75%), Postives = 164/283 (57.95%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRS-EAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF*IGNWCSHS 941
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S  A+EV         + ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F   N+C+++
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRASIWAEEV---------TKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF-PSNYCNNN 271
[Close]
BLAST of Endophilin-B1 vs. TrEMBL
Match: A0A455B8L5 (endophilin-B1 isoform X4 OS=Physeter macrocephalus OX=9755 GN=SH3GLB1 PE=4 SV=1)

HSP 1 Score: 166.007 bits (419), Expect = 3.369e-44
Identity = 102/269 (37.92%), Postives = 157/269 (58.36%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S+    A L  + ++S  +++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:   10 KLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRASQLNS-ARLEGDNIMS--EQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 268
[Close]
BLAST of Endophilin-B1 vs. TrEMBL
Match: A0A2U3WJP1 (endophilin-B1 isoform X3 OS=Odobenus rosmarus divergens OX=9708 GN=SH3GLB1 PE=4 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 3.406e-44
Identity = 101/287 (35.19%), Postives = 164/287 (57.14%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLL-----SDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF*IGNWCSHS 941
             ++ K  ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +I TEKI+K  E  +QPNP  R+E  VYEKLD K    I+   ++G  MI    +         P + Y  AL   GE+  +IG A +EL+  +   F+ PL++++E   K + KERK L+ KRLDLDA KT+LK+    E++ S+     +     ++     + ++++L+  Q EF++Q E+T LL+E + ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F   N+C+++
Sbjct:    6 FNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFG-------PGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRASQLNSARLEGDNNMIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF-PSNYCNNN 284
[Close]
BLAST of Endophilin-B1 vs. Ensembl Cavefish
Match: sh3glb1a (SH3-domain GRB2-like endophilin B1a [Source:ZFIN;Acc:ZDB-GENE-050417-89])

HSP 1 Score: 152.525 bits (384), Expect = 1.733e-42
Identity = 99/269 (36.80%), Postives = 151/269 (56.13%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            +F ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +  TE+I+K  E  +QPNP  R+E   YEKLD K    ++   ++G  MI        + N+  P + Y  AL   GE+  +IG A +E +  +   F+ P +++LE   K + KERK L+ KRLDLDA KTKLK+    E++ + +     L         ++DLK  Q EF++Q E+T LL+E V ++  +H R L DFV+ +  YY  C++ +  LQ+ L  F
Sbjct:    7 RFAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLTRAECTKHWTERILKQTEVLLQPNPNVRIEEFFYEKLDKKAPTRMNNHELLGQAMID-------SGNEFGPGTAYGNALVKCGETEKEIGGAEREFIQSSAINFLTPFRNFLEGDFKTILKERKLLQNKRLDLDAAKTKLKKAKMAEARAAVSYITLHLASSAYFRSAEQDLKMTQSEFDRQAEITRLLLEGVSSTHAHHLRCLNDFVEAQTTYYAQCYQYMVDLQKQLGSF 268
[Close]
BLAST of Endophilin-B1 vs. Ensembl Cavefish
Match: sh3glb1b (SH3-domain GRB2-like endophilin B1b [Source:ZFIN;Acc:ZDB-GENE-030131-6851])

HSP 1 Score: 140.969 bits (354), Expect = 1.922e-38
Identity = 89/269 (33.09%), Postives = 145/269 (53.90%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            +  ++A +  SR VQ+TEEKL   E+T  DA  E L+ + +  +  TE+++K  E  +QPNP  R+E  +YEKLD K     +   ++G+ MI    +         P + Y  AL   GE   ++G + +E ++ +   F+ P ++++E   K + KERK L+ KRLDLDA KT++K+    +++ +   E                L+  Q EF++Q E+T LL+E V ++  +H R L DFVD +A YY  C++ +  LQ+ L  F
Sbjct:   10 RLAADAGTLFSRAVQFTEEKLGQAERTELDAHLENLLGRAEATKHWTERVMKQTEVLLQPNPNVRMEEFLYEKLDRKLPTRANNHELLGECMIDAGHEFG-------PGTAYGSALIKCGEVEKQLGSSEKEFIHSSAINFLTPFRNFIEGDYKTISKERKLLQIKRLDLDAAKTRVKKARAADARSAAETE----------------LRIAQSEFDRQAEITRLLLEGVSSTHAHHLRCLNDFVDAQASYYAQCYQYMVNLQKQLGSF 255
[Close]
BLAST of Endophilin-B1 vs. Ensembl Cavefish
Match: sh3glb2a (SH3-domain GRB2-like endophilin B2a [Source:ZFIN;Acc:ZDB-GENE-061201-8])

HSP 1 Score: 126.331 bits (316), Expect = 7.185e-33
Identity = 93/268 (34.70%), Postives = 142/268 (52.99%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKK 911
            K   +A    SR VQYTEEKL   EKT  DA  E L+ + D  +  TEKI +  E  +QPNP+ R+E  +YEKLD K     +   I+G  M+  +++         P + Y   L   G+   ++G A +E +  +   F+ PL+++LE   + + KER+ LE +RLDLDA K +LK+    E+K +  +E                L+  Q EF++Q EVT LL+E + ++   H R L +FV+ +A YY  CH  + +LQ+ L +
Sbjct:    7 KLACDAGVFFSRAVQYTEEKLGQAEKTELDAHFESLLARADCTKNWTEKIYRQTEVLLQPNPSARIEEFLYEKLDRKLPYRATNGEILGQYMLEAAKEFG-------PGTPYGSTLIQVGDCQRRLGGAEREFLQTSSISFLTPLRNFLEGDWRTITKERRLLENRRLDLDACKARLKKAKAAEAKAAAEQE----------------LRLAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVEAQATYYNQCHHFMQELQKELSR 251
[Close]
BLAST of Endophilin-B1 vs. Ensembl Cavefish
Match: sh3glb2b (SH3-domain GRB2-like endophilin B2b [Source:ZFIN;Acc:ZDB-GENE-040426-833])

HSP 1 Score: 114.005 bits (284), Expect = 3.919e-28
Identity = 63/180 (35.00%), Postives = 95/180 (52.78%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTK 635
             ++ K  S+A    +R VQ+TEEKL   EKT  DA  E L+ + D  +  TEKI +  E  +QPNP+ R+E   YEKLD K     +   ++G  M   ++D         P + Y   L   GE   K+G + +E +  +   F+ PL+++LE   + + KER+ LE +RLDLD  K +
Sbjct:    3 FNVKKLASDAGVFFTRAVQFTEEKLGQAEKTELDAHLENLIARGDCTKNWTEKIFRQTEVLLQPNPSARIEEFFYEKLDKKAPTRTTNGELLGQYMQDAAKDFG-------PGTPYGSTLITVGEYQKKLGGSEREFLQSSAVGFLTPLRNFLEGDWRTISKERRLLENRRLDLDVCKAR 175
[Close]
BLAST of Endophilin-B1 vs. Ensembl Cavefish
Match: sh3gl1b (SH3 domain containing GRB2 like 1, endophilin A2 [Source:NCBI gene;Acc:103032391])

HSP 1 Score: 63.929 bits (154), Expect = 6.074e-11
Identity = 51/193 (26.42%), Postives = 89/193 (46.11%), Query Frame = 3 
Query:  144 RVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPA-----SIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQ-VKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRS-----EAKEVA 689
            +  Q   EK+   E T  D   + L  + D+      +++     ++QPNPA R +  +   +   R    SP       ++G+ M    +DL         ++N+ +AL   GES  ++      L    +  FI+PLQ   ++ ++ +Q   K+LEG+RLD D  K +  ++  EE K++     E+KEVA
Sbjct:   12 KASQMVSEKVGGAEGTKLDEEFKDLERKVDVTSKAVVELISKTSEYLQPNPASRAKLSMLNTMSKIRGQVKSPGYPQAEGLLGECMGKYGRDLGE-------ETNFGLALMDVGESMKRLAEVKDSLDIDVKQNFIDPLQGLCDKDLREIQHHLKKLEGRRLDYDYKKKRQGKIPDEEVKQALEKFHESKEVA 197
[Close]
BLAST of Endophilin-B1 vs. Ensembl Sea Lamprey
Match: SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2 [Source:HGNC Symbol;Acc:HGNC:10834])

HSP 1 Score: 149.828 bits (377), Expect = 4.272e-42
Identity = 91/282 (32.27%), Postives = 158/282 (56.03%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEK---------LLSD----TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            K  S+A +  SR VQ+TEEKL   E+T  DA  E L+ + ++ +  T+KI++  E+ +QPNP  R+E   +EKL+GK  +  + +  +G  MI   Q+         P + Y  AL   G +  ++G++ ++ +  T   F+ PL+++L+   + + KE+K LE KRLDLDA K++LK+  + E+K +   +   + P           L +D     +++L+  Q EF++Q E+T LL+E + ++   H R L +FV+ +A YY  C++ + +LQ+ L  F
Sbjct:    7 KLASDAGTFFSRAVQFTEEKLGQAERTELDAHFENLLGRAEMTRHWTDKIMRQAETLLQPNPNARIEDYFFEKLEGKAPLRATNSEYLGQYMIEAGQEFG-------PGTAYGCALIKCGTTQKELGISEKDFIQTTANGFLTPLRNFLDGDFRTIAKEKKILENKRLDLDACKSRLKKARSAEAKAATEPDFNEIRPRNYVLSASAAGLWADEVARAEQELRVTQTEFDRQAEITRLLLEGIGSTHANHHRALKEFVEAQAAYYAKCYQSMVELQKELGSF 281
[Close]
BLAST of Endophilin-B1 vs. Ensembl Sea Lamprey
Match: sh3glb1a (SH3-domain GRB2-like endophilin B1a [Source:ZFIN;Acc:ZDB-GENE-050417-89])

HSP 1 Score: 121.324 bits (303), Expect = 2.438e-33
Identity = 71/181 (39.23%), Postives = 99/181 (54.70%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKL 638
             ++ K  S+A +  +R VQ+TEEKL   E+T  DA  E LM + D  +  TEKI++  E  +QPNP  R+E  VYEKL+ K         ++G  M     D  A        + Y  AL   GES   +GLA +E +  +   F+ PL+++LE   K + KERK L+ KRLDLDA KT+L
Sbjct:    3 FNMKKLASDAGTFFTRAVQFTEEKLGGAERTELDAHFENLMTRADSTKNWTEKIMRQTEVVLQPNPTARVEEFVYEKLEKKGPARQRTVELLGQYMTDAGNDFGAG-------TPYGGALIKVGESQKLLGLAEKEFVQASTINFLTPLRNFLEGDYKAMAKERKLLQNKRLDLDASKTRL 176
[Close]
BLAST of Endophilin-B1 vs. Ensembl Sea Lamprey
Match: SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2 [Source:HGNC Symbol;Acc:HGNC:10834])

HSP 1 Score: 103.99 bits (258), Expect = 1.778e-26
Identity = 78/255 (30.59%), Postives = 127/255 (49.80%), Query Frame = 3 
Query:  153 QYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPA---YRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQ-VKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESL 905
            Q   E +   EKT  DA    L    D+ +  T+K++K +E  IQPNP+   +   S +Y  + G R V  +   I+G + +   Q+L        P +NY  AL  +GE+H ++G + +E ++     F+ PL  +L+  V  + +ERK LE KRLDLD +++KLKR   EE K+                         Q +F+ Q E T +L+E + ++   H   L  +VD +A+Y+E C +++  LQ+ L
Sbjct:    1 QMAGETVGQAEKTELDASFLKLFGDVDITRNWTDKLIKQVEVVIQPNPSKSHFSGVSTIY-YVRG-RSVGWTDTEILGQSFVDAGQELG-------PGTNYGAALTKAGETHKQLGTSEKEYIHVVSKDFLGPLHKFLDNDVAIIARERKALEAKRLDLDTLRSKLKRCTDEEEKQ-----------------------KAQAQFDHQAETTKILLEGLKSTHVSHLACLHHYVDAKAKYHEDCLQKLKTLQQDL 223
[Close]
BLAST of Endophilin-B1 vs. Ensembl Sea Lamprey
Match: SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2 [Source:HGNC Symbol;Acc:HGNC:10830])

HSP 1 Score: 66.2402 bits (160), Expect = 1.966e-12
Identity = 58/233 (24.89%), Postives = 101/233 (43.35%), Query Frame = 3 
Query:  144 RVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYR-----LESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTR 824
            +  Q+  EK+   E T  D     +  + D        I+   + ++QPNPA R     L +M   +   K   +  P  ++G+ M    +D+         +S + +AL   GES  ++      L    +  F++P+Q+  + ++K +    K+LEG+RLD D  K +L ++  EE +++E         EK     +    SM    E ++E  + L   V A L YH R
Sbjct:   14 KCTQFVSEKVGGAEGTKLDDDFTEMEKKYDTTNKAVMDIITKTQEYLQPNPASRAKLGMLNTMSKIRGQVKSTGYPQPEGLLGEAMAKYGKDMGT-------ESCFGLALADVGESMKQMAEIKDSLDIDVKQNFLDPMQALQDKELKEIGHHLKKLEGRRLDFDYKKKRLGKIPDEEIRQAE---------EKFEESREVAASSMHNLVESEIEQVSQLAALVDAQLEYHQR 230
[Close]
BLAST of Endophilin-B1 vs. Ensembl Sea Lamprey
Match: SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2 [Source:HGNC Symbol;Acc:HGNC:10830])

HSP 1 Score: 52.373 bits (124), Expect = 1.184e-8
Identity = 36/116 (31.03%), Postives = 61/116 (52.59%), Query Frame = 3 
Query:  360 PASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRS-----EAKEVA 689
            P   +G+ M+   QDL         +SN+  AL   GES+ ++      L    +  FI+PLQ   E +++ + +  K+LEG+RLD D  K +  +++ E+ ++S     E+KEVA
Sbjct:   27 PEGTLGECMVKYGQDLG-------EESNFGQALVDVGESYKEMAEVKDGLDIGVKQNFIDPLQGLQEKELREIGQHLKKLEGRRLDFDYKKKRQGKILEEDIRQSAEKFEESKEVA 135
[Close]
BLAST of Endophilin-B1 vs. Ensembl Nematostella
Match: EDO38201 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDK8])

HSP 1 Score: 134.42 bits (337), Expect = 2.092e-36
Identity = 81/249 (32.53%), Postives = 132/249 (53.01%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGK---RIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVD 845
            KF S  ++  SR  QYTEE+L   E T +DAR E L+ + D  +  TE+++K  E+ +QPNP  R E   Y KL  K   R+ H+       +T+  + +D     N++ P ++Y   L   G +  K+  A ++ M K+ + ++ PL+S+LE  +K +  ER+ L  KRLDLD+ K K+++  T               PE+ +   + +L+  Q EF++Q EVT LL++ +  S   H R L  F++
Sbjct:   10 KFGSTTATFFSRAKQYTEEQLGKAEATEFDARFESLLERADRTKQWTERLLKQTEALLQPNPGIRAEEYFYSKLGEKKPERLTHL-------ETLGKIMEDAG---NELGPGTSYGSTLVKCGATEKKLASAERDFMTKSVSHYLHPLKSFLEGDMKTISTERRTLLAKRLDLDSCKAKVRKAQT---------------PER-IQQAESELRVAQAEFDRQYEVTKLLLDGIATSHANHHRALQSFIE 232
[Close]
BLAST of Endophilin-B1 vs. Ensembl Nematostella
Match: EDO31161 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYP4])

HSP 1 Score: 58.5362 bits (140), Expect = 1.144e-9
Identity = 46/188 (24.47%), Postives = 93/188 (49.47%), Query Frame = 3 
Query:  138 VSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYR----LESMVYE-KLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQ--VKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAK 680
            +++  QY  EK+ + + +  +     L  +TD    L E ++   + ++QPNPA R    ++  V++ + + +   +  P   +G+TM+   QDL          S +  A+  +GE+  ++      L    +  F++PL + LE   +K + + RK+++G+RLD D  K K  ++  E+ + +E K
Sbjct:   10 INKANQYMSEKIGSAKGSQLEEEFVELERKTDSTAKLIEDVLHKTKEYLQPNPAARAKLSMQGAVHKVRGEARSTRYPQPEGNLGETMVKGGQDLGDT-------SLFGQAMVEAGETFLQLAEVKDALDANVKQNFLDPL-TQLENRDIKEIMQHRKKMQGRRLDYDCKKRKSNKLPLEDIRIAEEK 189
[Close]
BLAST of Endophilin-B1 vs. Ensembl Nematostella
Match: EDO47212 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMW0])

HSP 1 Score: 56.225 bits (134), Expect = 6.843e-9
Identity = 46/183 (25.14%), Postives = 85/183 (46.45%), Query Frame = 3 
Query:  138 VSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVAL-QLSGESHNKIGLAHQELMNKTRTKFIEPLQSY-LEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAK 680
            +++  QY  EK+ + E T  +     +  +TD    L   +    + ++QPN  Y  +  ++     ++  +     ++GD M+   Q++     Q+   S+Y+ AL   +G  H ++     EL  K  + F+ PL       +K +   RK+L+G+RLD D  K K  +V  EE K ++ K
Sbjct:   12 INKANQYVSEKMGSAEGTKMEDEFIEMERKTDALIELVANLTPKTKEYLQPNATYNAKVKMHMTQPDEKYPYTE--GLMGDVMMLAGQEI----GQVGKGSDYAAALLDFAGALH-ELAETRHELDEKVHSNFLGPLHDLEANDLKELTFNRKKLQGRRLDYDCKKRKGNKVSIEEIKTAQFK 187
[Close]
BLAST of Endophilin-B1 vs. Ensembl Medaka
Match: sh3glb1a (endophilin-B1 [Source:NCBI gene;Acc:101156208])

HSP 1 Score: 150.599 bits (379), Expect = 5.424e-42
Identity = 97/269 (36.06%), Postives = 152/269 (56.51%), Query Frame = 3 
Query:  111 KFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            +F ++A + +SR VQ+TEEKL   EKT  DA  E L+ + +  +  TEKI+K  E  +QPNP  RLE  VYEKL+ K    ++   ++G +MI        + ++  P + Y  AL   GE+  +IG A +E +      F+ P +++LE   K + KERK L+ KRLDLDA KT+LK+     ++ S+A+  A           +++L+  Q EF++Q E+T LL+E V ++  +H R L D V+ +  YY  C++ +  LQ+ L  F
Sbjct:    7 RFAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLVRAENTKQWTEKIMKQTEVLLQPNPNVRLEEFVYEKLEKKAPTRMNNHELLGQSMIE-------SGSEFGPGTAYGNALIKCGETQKQIGGAEREFIQSAAINFLTPFRNFLEGDFKTILKERKLLQVKRLDLDAAKTRLKK-----ARMSDARAAA-----------EQELRMTQSEFDRQAEITRLLLEGVSSTHAHHLRCLNDLVEAQTTYYAQCYQYMVDLQKQLGSF 252
[Close]
BLAST of Endophilin-B1 vs. Ensembl Medaka
Match: sh3glb2b (SH3 domain containing GRB2 like, endophilin B2 [Source:NCBI gene;Acc:101171759])

HSP 1 Score: 130.568 bits (327), Expect = 2.432e-34
Identity = 90/278 (32.37%), Postives = 148/278 (53.24%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLL--------SDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESL 905
             ++ K  S+A    +R VQ+TEEKL   EKT  D   E L+ + D  +  TEKI++  E  +QPNP+ R+E  +Y+KLD K    ++ A ++G  M+  +++  A+       S Y   L   GE   ++G A +E +  +   F+ PL+++LE   + + KE++ LE +RLDLD  K +LK+    E+K + A +     P   +        S  + +L+  Q EF++Q EVT LL+E + ++   H R L DF + +  Y+  CH  + +LQ  L
Sbjct:    3 FNVKKLASDAGVFFTRAVQFTEEKLGQAEKTELDPHLENLITRADSTKNWTEKILRQTEVLLQPNPSARIEEFIYDKLDKKLPSRMTTAELLGQYMLDAAKEFGAD-------SPYGSTLITVGEYQKRLGGAEREFLQTSAAAFLSPLRNFLEGDWRTISKEKRLLENRRLDLDICKARLKKAKHAEAKAAAAPDFQETRPRNYVLSASASAVSSAEHELRVAQTEFDRQAEVTRLLLEGISSTHLNHLRCLQDFAEAQTTYFSQCHHHMQELQREL 273
[Close]
BLAST of Endophilin-B1 vs. Ensembl Medaka
Match: sh3glb2b (SH3 domain containing GRB2 like, endophilin B2 [Source:NCBI gene;Acc:101171759])

HSP 1 Score: 129.028 bits (323), Expect = 4.375e-33
Identity = 89/285 (31.23%), Postives = 148/285 (51.93%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSD-------------TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKK 911
             ++ K  S+A    +R VQ+TEEKL   EKT  D   E L+ + D  +  TEKI++  E  +QPNP+ R+E  +Y+KLD K    ++ A ++G  M+  +++  A+       S Y   L   GE   ++G A +E +  +   F+ PL+++LE   + + KE++ LE +RLDLD  K +LK+    E+K + A +     P   +                + +L+  Q EF++Q EVT LL+E + ++   H R L DF + +  Y+  CH  + +LQ  L +
Sbjct:  102 FNVKKLASDAGVFFTRAVQFTEEKLGQAEKTELDPHLENLITRADSTKNWTEKILRQTEVLLQPNPSARIEEFIYDKLDKKLPSRMTTAELLGQYMLDAAKEFGAD-------SPYGSTLITVGEYQKRLGGAEREFLQTSAAAFLSPLRNFLEGDWRTISKEKRLLENRRLDLDICKARLKKAKHAEAKAAAAPDFQETRPRNYVLSASASALLSEEVDKAEHELRVAQTEFDRQAEVTRLLLEGISSTHLNHLRCLQDFAEAQTTYFSQCHHHMQELQRELHR 379
[Close]
BLAST of Endophilin-B1 vs. Ensembl Medaka
Match: ENSORLT00000021068.2 (endophilin-B2 [Source:NCBI gene;Acc:101169212])

HSP 1 Score: 126.716 bits (317), Expect = 5.675e-33
Identity = 91/276 (32.97%), Postives = 148/276 (53.62%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLL-----SDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLK 908
             ++ +  + A   ++R VQ+TEEKL+  EKT  D   E L  + D  +  TEKI++  E  +QPNP+ R+E  +YEKLD K    ++ + ++G  M   +++L         +S Y   L   GE   ++G   ++ +      F+ PL+++LE   + + KER+ LE  RLDLDA KT++K+    E+K +   +     P   +     S  ++ LK+ Q EF++Q EVT LL+E +  +   H R L +FV+ +A YY  CH  +  LQE L+
Sbjct:    3 FNVKRLATEAGLFLTRAVQFTEEKLWQSEKTNLDQDFENLTVRADCTKHWTEKILRQTEILLQPNPSARIEEFLYEKLDMKAPSRVTNSELLGQHMEDAAKELGL-------ESPYGSTLVKVGECERRLGAVEKDFIQTADISFLSPLRNFLEGDCRIISKERRLLENLRLDLDACKTRVKKAKAAEAKVAVVPDFQETRPRNYVLSASASAAEQGLKTAQKEFDRQAEVTRLLLEGISCTHVNHLRCLHEFVEAQAAYYRQCHLHMQDLQEELR 271
[Close]
BLAST of Endophilin-B1 vs. Ensembl Medaka
Match: sh3glb2b (SH3 domain containing GRB2 like, endophilin B2 [Source:NCBI gene;Acc:101171759])

HSP 1 Score: 123.25 bits (308), Expect = 5.822e-31
Identity = 89/289 (30.80%), Postives = 147/289 (50.87%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNP----AYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSD-------------TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKK 911
             ++ K  S+A    +R VQ+TEEKL   EKT  D   E L+ + D  +  TEKI++  E  +QPNP      R+E  +Y+KLD K    ++ A ++G  M+  +++  A+       S Y   L   GE   ++G A +E +  +   F+ PL+++LE   + + KE++ LE +RLDLD  K +LK+    E+K + A +     P   +                + +L+  Q EF++Q EVT LL+E + ++   H R L DF + +  Y+  CH  + +LQ  L +
Sbjct:  102 FNVKKLASDAGVFFTRAVQFTEEKLGQAEKTELDPHLENLITRADSTKNWTEKILRQTEVLLQPNPIDHTGARIEEFIYDKLDKKLPSRMTTAELLGQYMLDAAKEFGAD-------SPYGSTLITVGEYQKRLGGAEREFLQTSAAAFLSPLRNFLEGDWRTISKEKRLLENRRLDLDICKARLKKAKHAEAKAAAAPDFQETRPRNYVLSASASALLSEEVDKAEHELRVAQTEFDRQAEVTRLLLEGISSTHLNHLRCLQDFAEAQTTYFSQCHHHMQELQRELHR 383
[Close]
BLAST of Endophilin-B1 vs. Planmine SMEST
Match: SMESG000051256.1 (SMESG000051256.1)

HSP 1 Score: 500.36 bits (1287), Expect = 2.697e-180
Identity = 262/272 (96.32%), Postives = 263/272 (96.69%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEE+KRSEAKEVAM         TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDCEAEYYEHCHEEITKLQESLKKF
Sbjct:    1 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEEAKRSEAKEVAM---------TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDCEAEYYEHCHEEITKLQESLKKF 263
[Close]
BLAST of Endophilin-B1 vs. Planmine SMEST
Match: SMESG000051256.1 (SMESG000051256.1)

HSP 1 Score: 484.182 bits (1245), Expect = 5.979e-174
Identity = 255/272 (93.75%), Postives = 256/272 (94.12%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDXXXXXXXXXXXXITKLQESLKKF 914
            MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEE+KRS                TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDCEAEYYEHCHEEITKLQESLKKF
Sbjct:    1 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEEAKRS----------------TDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDCEAEYYEHCHEEITKLQESLKKF 256
[Close]
BLAST of Endophilin-B1 vs. Planmine SMEST
Match: SMESG000000639.1 (SMESG000000639.1)

HSP 1 Score: 137.887 bits (346), Expect = 2.530e-38
Identity = 85/234 (36.32%), Postives = 127/234 (54.27%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENV 797
            MD  KF+S AS+A++R VQ TEE     EKT YD     L  + DL Q+ TE I+K IE F +PNPA R+ES+V EKL+ K+   ++ A  +G+T++           +I  ++ Y   L  +G+S   IG A ++L NK    +I  L+++L   +KN+  ERK LE  RLDLD  K K+K+  TE++                +   D +LK  Q +F+ QL +  L +E +
Sbjct:    1 MDFKKFVSGASTALNRAVQKTEETFLQAEKTEYDPYFVDLAKKCDLTQVWTEAIIKDIEVFAEPNPANRMESLVNEKLERKQTDRMNAAEELGNTLMKAGA-------EIGIETTYGKTLMKAGQSEIYIGRAKKQLGNKIVNNYIGTLKAFLNTDLKNINTERKTLENLRLDLDLAKNKMKKAKTEQA----------------IQIADCELKKAQGDFDDQLVIAKLHLEGI 211
[Close]
BLAST of Endophilin-B1 vs. Planmine SMEST
Match: SMESG000000639.1 (SMESG000000639.1)

HSP 1 Score: 131.339 bits (329), Expect = 8.932e-36
Identity = 85/240 (35.42%), Postives = 127/240 (52.92%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAY------RLESMVYEKLDGKRIVHISPASIVGDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENV 797
            MD  KF+S AS+A++R VQ TEE     EKT YD     L  + DL Q+ TE I+K IE F +PNPA       R+ES+V EKL+ K+   ++ A  +G+T++           +I  ++ Y   L  +G+S   IG A ++L NK    +I  L+++L   +KN+  ERK LE  RLDLD  K K+K+  TE++                +   D +LK  Q +F+ QL +  L +E +
Sbjct:    1 MDFKKFVSGASTALNRAVQKTEETFLQAEKTEYDPYFVDLAKKCDLTQVWTEAIIKDIEVFAEPNPASLFKFANRMESLVNEKLERKQTDRMNAAEELGNTLMKAGA-------EIGIETTYGKTLMKAGQSEIYIGRAKKQLGNKIVNNYIGTLKAFLNTDLKNINTERKTLENLRLDLDLAKNKMKKAKTEQA----------------IQIADCELKKAQGDFDDQLVIAKLHLEGI 217
[Close]
BLAST of Endophilin-B1 vs. Planmine SMEST
Match: SMESG000013676.1 (SMESG000013676.1)

HSP 1 Score: 94.7449 bits (234), Expect = 2.614e-22
Identity = 71/256 (27.73%), Postives = 120/256 (46.88%), Query Frame = 3 
Query:   99 MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQILTEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIV-------GDTMISVSQDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQSYLE-QVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLPPEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFV 842
            MD  K +S A + ++R VQ T E L + EKT YD   + ++ + D   + TE+ VK   S ++PN A+RLE  V +K+D K    I+P  ++       G+T   +S DL             S      G    ++G+  +E   +    ++  L++ +   +K  Q+ER  LE  RLDLD+++ KLKR  + E+ R  A++                 ++ +++F QQL +   +  N+      H  L+  FV
Sbjct:    1 MDFKKLVSEAGAKLNRAVQKTNETLLSAEKTEYDIEYKNMLTKIDALNVWTERFVKEATSALEPNLAFRLEDKVLDKIDRKN-ERITPLEVLGGVYEKAGETFAPLSGDL-------------SKCFATFGGIEVRVGITSKEFQKRASEVYVSKLRTMITVDLKKFQEERVNLENLRLDLDSLRGKLKR--SSENNRRSAEDA---------------FQNAEIKFNQQLNMNKEIFANIDKLFDEHQTLIKAFV 225
The following BLAST results are available for this feature:
BLAST of Endophilin-B1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SH3GLB11.431e-4636.59SH3 domain containing GRB2 like, endophilin B1 [So... [more]
SH3GLB17.860e-4636.26SH3 domain containing GRB2 like, endophilin B1 [So... [more]
SH3GLB14.309e-4535.19SH3 domain containing GRB2 like, endophilin B1 [So... [more]
SH3GLB22.659e-3032.13SH3 domain containing GRB2 like, endophilin B2 [So... [more]
SH3GLB26.395e-3031.47SH3 domain containing GRB2 like, endophilin B2 [So... [more]
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BLAST of Endophilin-B1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
F35A5.81.149e-3130.63pep chromosome:WBcel235:X:3800737:3802771:-1 gene:... [more]
F35A5.89.271e-3131.09pep chromosome:WBcel235:X:3800045:3802771:-1 gene:... [more]
F35A5.81.238e-3030.83pep chromosome:WBcel235:X:3800045:3802767:-1 gene:... [more]
unc-573.080e-822.89Endophilin-A homolog [Source:UniProtKB/Swiss-Prot... [more]
unc-573.153e-822.89Endophilin-A homolog [Source:UniProtKB/Swiss-Prot... [more]
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BLAST of Endophilin-B1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
EndoB4.936e-3633.71gene:FBgn0034433 transcript:FBtr0113097[more]
EndoB6.870e-3634.02gene:FBgn0034433 transcript:FBtr0086558[more]
EndoB1.488e-3232.58gene:FBgn0034433 transcript:FBtr0113098[more]
EndoB2.130e-3232.79gene:FBgn0034433 transcript:FBtr0086559[more]
EndoA2.643e-923.19gene:FBgn0038659 transcript:FBtr0083699[more]
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BLAST of Endophilin-B1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sh3glb1a1.122e-3936.43SH3-domain GRB2-like endophilin B1a [Source:ZFIN;A... [more]
sh3glb1a1.122e-3936.43SH3-domain GRB2-like endophilin B1a [Source:ZFIN;A... [more]
sh3glb1b5.771e-3833.09SH3-domain GRB2-like endophilin B1b [Source:ZFIN;A... [more]
sh3glb1b2.652e-3732.63SH3-domain GRB2-like endophilin B1b [Source:ZFIN;A... [more]
sh3glb1b5.072e-3733.08SH3-domain GRB2-like endophilin B1b [Source:ZFIN;A... [more]
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BLAST of Endophilin-B1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sh3glb19.838e-4534.66SH3 domain GRB2 like, endophilin B1 [Source:NCBI g... [more]
sh3glb11.541e-4435.16SH3 domain GRB2 like, endophilin B1 [Source:NCBI g... [more]
sh3glb18.746e-4332.89SH3 domain GRB2 like, endophilin B1 [Source:NCBI g... [more]
sh3glb11.667e-4035.69SH3 domain GRB2 like, endophilin B1 [Source:NCBI g... [more]
sh3glb16.384e-4035.29SH3 domain GRB2 like, endophilin B1 [Source:NCBI g... [more]
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BLAST of Endophilin-B1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sh3glb12.402e-4736.43SH3-domain GRB2-like B1 (endophilin) [Source:MGI S... [more]
Sh3glb11.431e-4636.63SH3-domain GRB2-like B1 (endophilin) [Source:MGI S... [more]
Sh3glb12.229e-4636.63SH3-domain GRB2-like B1 (endophilin) [Source:MGI S... [more]
Sh3glb16.028e-4535.66SH3-domain GRB2-like B1 (endophilin) [Source:MGI S... [more]
Sh3glb23.903e-3031.77SH3-domain GRB2-like endophilin B2 [Source:MGI Sym... [more]
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BLAST of Endophilin-B1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9JK48|SHLB1_MOUSE1.559e-4536.63Endophilin-B1 OS=Mus musculus OX=10090 GN=Sh3glb1 ... [more]
sp|Q6AYE2|SHLB1_RAT2.782e-4536.26Endophilin-B1 OS=Rattus norvegicus OX=10116 GN=Sh3... [more]
sp|Q5R8P5|SHLB1_PONAB3.775e-4536.26Endophilin-B1 OS=Pongo abelii OX=9601 GN=SH3GLB1 P... [more]
sp|Q9Y371|SHLB1_HUMAN3.775e-4536.26Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 P... [more]
sp|Q32LM0|SHLB1_BOVIN4.063e-4536.26Endophilin-B1 OS=Bos taurus OX=9913 GN=SH3GLB1 PE=... [more]
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BLAST of Endophilin-B1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1Q9631.375e-4637.10Endophilin-B1 OS=Crassostrea gigas OX=29159 GN=CGI... [more]
A0A4D9EDM22.227e-4436.63Growth factor receptor-bound protein 2 OS=Platyste... [more]
A0A3Q7PCI82.232e-4436.75endophilin-B1 isoform X3 OS=Callorhinus ursinus OX... [more]
A0A455B8L53.369e-4437.92endophilin-B1 isoform X4 OS=Physeter macrocephalus... [more]
A0A2U3WJP13.406e-4435.19endophilin-B1 isoform X3 OS=Odobenus rosmarus dive... [more]
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BLAST of Endophilin-B1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sh3glb1a1.733e-4236.80SH3-domain GRB2-like endophilin B1a [Source:ZFIN;A... [more]
sh3glb1b1.922e-3833.09SH3-domain GRB2-like endophilin B1b [Source:ZFIN;A... [more]
sh3glb2a7.185e-3334.70SH3-domain GRB2-like endophilin B2a [Source:ZFIN;A... [more]
sh3glb2b3.919e-2835.00SH3-domain GRB2-like endophilin B2b [Source:ZFIN;A... [more]
sh3gl1b6.074e-1126.42SH3 domain containing GRB2 like 1, endophilin A2 [... [more]
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BLAST of Endophilin-B1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SH3GLB24.272e-4232.27SH3 domain containing GRB2 like, endophilin B2 [So... [more]
sh3glb1a2.438e-3339.23SH3-domain GRB2-like endophilin B1a [Source:ZFIN;A... [more]
SH3GLB21.778e-2630.59SH3 domain containing GRB2 like, endophilin B2 [So... [more]
SH3GL11.966e-1224.89SH3 domain containing GRB2 like 1, endophilin A2 [... [more]
SH3GL11.184e-831.03SH3 domain containing GRB2 like 1, endophilin A2 [... [more]
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BLAST of Endophilin-B1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endophilin-B1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO382012.092e-3632.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO311611.144e-924.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO472126.843e-925.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Endophilin-B1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sh3glb1a5.424e-4236.06endophilin-B1 [Source:NCBI gene;Acc:101156208][more]
sh3glb2b2.432e-3432.37SH3 domain containing GRB2 like, endophilin B2 [So... [more]
sh3glb2b4.375e-3331.23SH3 domain containing GRB2 like, endophilin B2 [So... [more]
ENSORLT00000021068.25.675e-3332.97endophilin-B2 [Source:NCBI gene;Acc:101169212][more]
sh3glb2b5.822e-3130.80SH3 domain containing GRB2 like, endophilin B2 [So... [more]
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BLAST of Endophilin-B1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000051256.12.697e-18096.32SMESG000051256.1[more]
SMESG000051256.15.979e-17493.75SMESG000051256.1[more]
SMESG000000639.12.530e-3836.32SMESG000000639.1[more]
SMESG000000639.18.932e-3635.42SMESG000000639.1[more]
SMESG000013676.12.614e-2227.73SMESG000013676.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029068 ID=SMED30029068|Name=Endophilin-B1|organism=Schmidtea mediterranea sexual|type=transcript|length=1076bp
CTCTGTTAAAGCGTAATATTCATTTAGTGTTCAATTTTTATATTGAATTA
TAAATTCTCTAAATTTTTTTTTCTCATTTTTAAAAAAAAACTATTTACAT
GGATCTCGGGAAATTTATTTCAAATGCTTCTAGTGCTGTTTCCCGAGTTG
TTCAATATACAGAGGAAAAGTTATTTAATGTTGAAAAGACTGCTTATGAT
GCTCGTACTGAATATCTAATGCACCAAACAGATCTTTGTCAAATACTAAC
TGAAAAAATTGTTAAATCCATTGAAAGTTTTATCCAACCAAATCCAGCCT
ATAGACTAGAAAGTATGGTATATGAGAAGCTTGATGGAAAACGAATCGTT
CATATATCTCCAGCCAGTATTGTCGGTGACACAATGATTTCAGTTAGTCA
GGATTTGAAAGCAAACCCGAATCAAATCGAACCTCAAAGCAATTACAGTG
TTGCATTGCAACTTTCCGGAGAAAGTCACAATAAAATTGGATTAGCTCAT
CAAGAGCTCATGAACAAAACCAGAACAAAGTTTATTGAACCTCTTCAAAG
CTATCTTGAACAAGTTAAAAATGTCCAGAAAGAACGTAAAGAATTAGAGG
GGAAACGTCTGGATTTAGATGCAATTAAAACCAAATTAAAACGTGTCGTA
ACTGAAGAATCCAAAAGATCTGAAGCGAAAGAGGTCGCAATGTTACCGCC
GGAAAAACTTCTTTCAGATACTGATAGAGATTTAAAAAGTATGCAAATGG
AATTTGAACAACAATTAGAAGTGACAAATCTATTGATGGAGAACGTTGTT
GCTTCTTTGGGTTATCACACGAGACTACTCTGTGATTTTGTTGATTGCGA
GGCTGAGTATTATGAACATTGTCATGAAGAAATCACTAAATTGCAAGAGT
CTTTGAAAAAATTTTAGATTGGTAATTGGTGCAGTCACTCATTATTTATT
ATGAAATTACTCGTTTTTATTATATATTAATTTCCATAATTAGTATTATT
ATAAAATTCCTTCGTGATTTGTGCTGTCGTACCTGGAGATTAATACAATT
TTTGTATTGTTGGCATTATATTCAAT
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protein sequence of SMED30029068-orf-1

>SMED30029068-orf-1 ID=SMED30029068-orf-1|Name=SMED30029068-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=273bp
MDLGKFISNASSAVSRVVQYTEEKLFNVEKTAYDARTEYLMHQTDLCQIL
TEKIVKSIESFIQPNPAYRLESMVYEKLDGKRIVHISPASIVGDTMISVS
QDLKANPNQIEPQSNYSVALQLSGESHNKIGLAHQELMNKTRTKFIEPLQ
SYLEQVKNVQKERKELEGKRLDLDAIKTKLKRVVTEESKRSEAKEVAMLP
PEKLLSDTDRDLKSMQMEFEQQLEVTNLLMENVVASLGYHTRLLCDFVDC
EAEYYEHCHEEITKLQESLKKF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR028503SH3GLB1
IPR004148BAR_dom
IPR027267AH/BAR_dom_sf
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 149..179
NoneNo IPR availablePANTHERPTHR14167SH3 DOMAIN-CONTAININGcoord: 7..261
IPR004148BAR domainSMARTSM007215barcoord: 9..271
e-value: 3.5E-34
score: 129.6
IPR004148BAR domainPFAMPF03114BARcoord: 12..270
e-value: 2.7E-44
score: 151.6
IPR004148BAR domainPROSITEPS51021BARcoord: 22..272
score: 23.528
IPR027267AH/BAR domain superfamilyGENE3DG3DSA:1.20.1270.60coord: 23..271
e-value: 5.7E-51
score: 175.7
IPR027267AH/BAR domain superfamilySUPERFAMILYSSF103657BAR/IMD domain-likecoord: 15..271
IPR028503Endophilin-B1PANTHERPTHR14167:SF52ENDOPHILIN-B1coord: 7..261