4Fe-4S ferredoxin-type domain-containing protein

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++++F P+ ++W+ S LLP IVYYS ++  HWTK+ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF   + + +       C+F P   AFFVNY+I +AFIG   EL+R+P LI+Y +  I+ +++ +   +++N  ++++FG  Y+W+LCVFTV V YS  CP+I PFGLIYI+ K+ VDR+N+YF Y  + +   IH  A++  + A
Sbjct:  460 NPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEAS---IRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKGIHFAAVNQALAA 674          

Query:  111 DRVN---IYRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFD----KGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEV-----DVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLL---NYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIK 1352
            DR N    Y    ++ V+ G  F GIP    I++  F+ L ++F  +R+  W++GRIAL++                                E D ++  +R S   ++ Q D     G   WL   + + D  I E  G DA  YL FQ+++IF   +++ +SL VILPVN+ G+        F  TTI NL + + ++W+H + + +Y F  +  + H   +++    N    TL I G+P+++     +  HF++AYP C + D+Q  +N+ KLI+L  +++    +          TG R  + PK CG+F  CC E +     D I YY      L  +  +E     D+ +G+AFVTF+    A  +L+D+++  C  L     PQ S+ S ++ ++ WT+++A     I W+NL     +W ++
Sbjct:   25 DRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVS--------------------------------EADSESRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFLTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDAR-KETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLINPKPCGQF--CCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQ 421          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF  + +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+    + RS+ E   ++++  +EFQFG  Y+W++CVFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  + ++ KIH  A++  V A
Sbjct:  288 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAA 503          

Query:  636 DFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCC-----IEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYH----SSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
             F  TTI NL S + ++W+H   +FLY    +  +    + ++    +    TL I+GI K +     I  HF+EAYP C + + +  +N+ +L+ L+ +R+ A   +       +   +   + PK CG  H CC      E+V+ I+YY      L+   ++E  K  +K +G+AFVTF        +L+D++      C+    P+ S+ S  +  + WT+SYAP    I WE+L
Sbjct:    5 SFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAE-SEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCG--HLCCCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHL 239          

Query: 1442 IKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            I+K+  N ++ +F PS ++W  + +LP IVY+S  +  HWT++ ++  ++ K Y FL+ MV+ILPS+G+ SL  F+ WLF I  ++  +  F   C+F P N AFFVNY+ITAA +GT  EL+R+  L  Y       RS  E   IRKN   +FQFG  Y+W++ VF+V + YS  CP+IVPFGL+Y+  K+  DRYN+Y+++  + +N +IH  A+S  +FA
Sbjct:  443 IEKLQ-NPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQ--CVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFA 663          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTG---IRRTMVPKFCGRFHSC--CIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDY-HSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            F G+P    +NI  ++++ V++ FLRK AW++GR+ALL  N        G         SEK    ET S E + +               DKGF SW      + D+D+  K G+DA  Y++FQ +LI    II + SL +ILP+N  G+      + FA TTI+N+S+ S+++W+H++LSF YF      + H           + + TL+I  +PK+     +I+ HF EAYP   +  + F +++R LI L+ QR  A+  +     +   TG   IR     + C  F  C  C +EVD   YY++    L  +   E+ +   K++ + FVTF+    A++V +DY +  C +   PQ S+++  +KS YW ++ AP    I W++L
Sbjct:   35 FGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQ-------SEKTSPSET-SLEMERR---------------DKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWS-SHFARTTIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLFYTAKAKKTGKVMIRIHPCARLC--FCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGV--QPQQSSVTTIVKSYYWRVTMAPHPKDIIWKHL 399          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF  + +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+    + RS+ E   ++++  +EFQFG  Y+W++CVFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  + ++ KIH  A++  V A
Sbjct:  401 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAA 616          

Query:  234 LRKNAWNHGRIALLTKNRRKEQSSTG--YNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCC-----IEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYH----SSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            LRK AW++GR+AL+T       +  G  ++ +  +T         + S +FD++               D GF SWL   + + D +IR+K G DA  YL FQ+++I    ++ V+S+ ++LPVN  G+  +     F  TTI NL S + ++W+H   +FLY    +  +    + ++    +    TL I+GI K +     I  HF+EAYP C + + +  +N+ +L+ L+ +R+ A   +       +   +   + PK CG  H CC      E+V+ I+YY      L+   ++E  K  +K +G+AFVTF        +L+D++      C+    P+ S+ S  +  + WT+SYAP    I WE+L
Sbjct:    4 LRKVAWDYGRLALVTDADSVASAMHGDSHDRYERLT-------SVSSSVDFDQR---------------DNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAE-SEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCG--HLCCCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHL 352          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF  + +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+    + RS+ E   ++++  +EFQFG  Y+W++CVFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  + ++ KIH  A++  V A
Sbjct:  472 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAA 687          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLT---KNRRKEQSSTGYNIWNTVTLSEKNENEE-----TDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCC-----IEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYH----SSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            F G+P    ++ + F+ L  LF  LRK AW++GR+AL+T   + RR+E+         +    + ++  E     + S +FD++               D GF SWL   + + D +IR+K G DA  YL FQ+++I    ++ V+S+ ++LPVN  G+  +     F  TTI NL S + ++W+H   +FLY    +  +    + ++    +    TL I+GI K +     I  HF+EAYP C + + +  +N+ +L+ L+ +R+ A   +       +   +   + PK CG  H CC      E+V+ I+YY      L+   ++E  K  +K +G+AFVTF        +L+D++      C+    P+ S+ S  +  + WT+SYAP    I WE+L
Sbjct:   38 FGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQERDRVEQEYVASAMHGDSHDRYERLTSVSSSVDFDQR---------------DNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAE-SEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCG--HLCCCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHL 423          

Query: 1478 FLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFI----NSKIHRLAMSFTVFA 2113
            FLP+ ++W +S L+P IV  S+  + H+T++ ++ +++ K + +L++M++ILPSLG+ S  + + W F  Q  +       W CIF P   +F+VNYIITAAFIGT  EL+R PELI+Y++  +  +S  E   IRK ++ EF FG  Y+W   VFT+ + YS  CPLI+PF +IYI  K+ VDR+N+YFAY  S +      KIH  A++ T F+
Sbjct:  443 FLPTLMLWTLSALMPVIVAISDKWMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFLNQTDR-------WQCIFLPDRGSFYVNYIITAAFIGTALELLRFPELIVYIWSLLKAKSKAETPYIRKAILIEFPFGTHYAWTTLVFTIAIVYSVACPLIMPFAMIYICLKHFVDRHNLYFAYGPSNMISRKGGKIHSTAVTMTKFS 651          

Query:  159 GFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKN---ENEETDSTEFDEKTYLRRASVIDTTS----QFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKY--NDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMV--PKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIK 1352
             + GIP+   +N + +++L +LF  LR  A + GR+AL+  N  K++       W  +  S      + + + ST+   +       V D+T     Q ++G F W++    +  + I    G DA  YL FQ++L+    ++T++SL++ILPVN      +  Y  N F  TT+ NLS  S  +WVH +++ LY   ++ +I   A+         A+ T++I  I       +++ ++ +E +P   I+++  A+N+ +L   N + E  +H        + N   R T++  P+ C      C +E +  +YY  E   L     +      ++ + +AF+T  T+++A+ ++  +        Y Q            W + +AP  + + WENL      W +K
Sbjct:   25 AYNGIPETLILNTIFWVLLILLFTVLRHQAGDFGRLALVNSNGSKKR-------WTEIFYSRAASVVDPQPSTSTQVSPRPSTTSQGVPDSTPLSPIQPEEGLFGWIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALVTIVSLVIILPVNFLNGPKENPYDVNAFGRTTMANLSPDSPWLWVHTIITILY-IPLVVLIMRRASGRNAFK-KAATRTIMISNISSSDRNKTVVRNYMQELFPDVTIENVSIAYNISRLYVRNAEFE-RVHEARLYCEHHRN---RDTLMVKPEMCS-----CKKE-NAYEYYQREERKLSGDVARLRASTMNEPLDIAFITVSTVQEAQNIVTHFTPG----TYRQ------------WHLVFAPSPDDLFWENLNVNKSHWYLK 398          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N V+ +F P+ ++WA S LLPFIVYYS     HWT++ E+   + K +  L+ MV+ILPSLG++SL  F  WLF ++ +      F   C+F P N AFFVNY+IT++ IGT  EL+RIP L++Y       +S  E   ++ +  +EFQFGL Y+W +C+F+V++TYS  CP+IVPFGL+Y++ K+ VDRYNIY+AY  + +N +IH  A+S  V A
Sbjct:  476 NPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQ--CVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVA 691          

Query:  126 YRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKF-CGRFHSCCI---EEVDVIDYYN--DEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL--CHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            YR  + ++V+ G  F G+P    IN+V ++IL ++F  LRK AW++GR+ALL KN          +   ++   E++E E+T S      +  +           D GF SWL   Y + D++IR K G DA  YL FQ+++I    ++ ++SL +ILPVN+ GN       +F  TT++N+ + +  +W+H++ + LYF   +  + H ++ L+     + + TL+I  IP+E S   +I  H  EAYP C + DI F  N++KL+ L+ +R  A+  +     +    G  R M+    C +   C I   E+VD   YY+  +E L  E   +K  +    K++G+AFVTF        +++DY S     + PQ S+++  ++S  W +SYAP  N I WENL  C P  +W ++ IL+N +LF+ LF LTTP   +N +
Sbjct:   47 YRSHSRSSVLQGLPFGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKN----------DSLTSLFYGEQSEKEKTPSDSSPSDSETK-----------DMGFCSWLTSLYHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLGDNPENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLYFTTKAQKNG--RIMIKTHPCAQIFCCDICGFEKVDAEQYYSELEEKLTDEFNAEKNWISM--KRLGIAFVTFRDERMTAVIVKDY-SRARCRHRPQQSSITTVVRSHQWDVSYAPAPNDIIWENLSVCGP--RWWLRCILLNILLFLLLFFLTTPAIIVNTM 462          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N V+ +F P+ ++WA S LLPFIVYYS     HWT++ E+   + K +  L+ MV+ILPSLG++SL  F  WLF ++ +      F   C+F P N AFFVNY+IT++ IGT  EL+RIP L++Y       +S  E   ++ +  +EFQFGL Y+W +C+F+V++TYS  CP+IVPFGL+Y++ K+ VDRYNIY+AY  + +N +IH  A+S  V A
Sbjct:  463 NPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQ--CVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVA 678          

Query:  126 YRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKF-CGRFHSCCI---EEVDVIDYYN--DEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL--CHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            YR  + ++V+ G  F G+P    IN+V ++IL ++F  LRK AW++GR+ALL KN          +   ++   E++E E+T S      +  +           D GF SWL   Y + D++IR K G DA  YL FQ+++I    ++ ++SL +ILPVN+ GN       +F  TT++N+ + +  +W+H++ + LYF   +  + H ++ L+     + + TL+I  IP+E S   +I  H  EAYP C + DI F  N++KL+ L+ +R  A+  +     +    G  R M+    C +   C I   E+VD   YY+  +E L  E   +K  +    K++G+AFVTF        +++DY S     + PQ S+++  ++S  W +SYAP  N I WENL  C P  +W ++ IL+N +LF+ LF LTTP   +N +
Sbjct:   34 YRSHSRSSVLQGLPFGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKN----------DSLTSLFYGEQSEKEKTPSDSSPSDSETK-----------DMGFCSWLTSLYHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLGDNPENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLYFTTKAQKNG--RIMIKTHPCAQIFCCDICGFEKVDAEQYYSELEEKLTDEFNAEKNWISM--KRLGIAFVTFRDERMTAVIVKDY-SRARCRHKPQQSSITTVVRSHQWDVSYAPAPNDIIWENLSVCGP--RWWLRCILLNILLFLLLFFLTTPAIIVNTM 449          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N V+ +F P+ ++WA S LLPFIVYYS     HWT++ E+   + K +  L+ MV+ILPSLG++SL  F  WLF ++ +      F   C+F P N AFFVNY+IT++ IGT  EL+RIP L++Y       +S  E   ++ +  +EFQFGL Y+W +C+F+V++TYS  CP+IVPFGL+Y++ K+ VDRYNIY+AY  + +N +IH  A+S  V A
Sbjct:  459 NPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQ--CVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVA 674          

Query:  126 YRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKF-CGRFHSCCI---EEVDVIDYYN--DEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL--CHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            YR  + ++V+ G  F G+P    IN+V ++IL ++F  LRK AW++GR+ALL KN          +   ++   E++E E+T S      +  +           D GF SWL   Y + D++IR K G DA  YL FQ+++I    ++ ++SL +ILPVN+ GN       +F  TT++N+ + +  +W+H++ + LYF   +  + H ++ L+     + + TL+I  IP+E S   +I  H  EAYP C + DI F  N++KL+ L+ +R  A+  +     +    G  R M+    C +   C I   E+VD   YY+  +E L  E   +K  +    K++G+AFVTF        +++DY S     + PQ S+++  ++S  W +SYAP  N I WENL  C P  +W ++ IL+N +LF+ LF LTTP   +N +
Sbjct:   34 YRSHSRSSVLQGLPFGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKN----------DSLTSLFYGEQSEKEKTPSDSSPSDSETK-----------DMGFCSWLTSLYHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGN----LLENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLYFTTKAQKNG--RIMIKTHPCAQIFCCDICGFEKVDAEQYYSELEEKLTDEFNAEKNWISM--KRLGIAFVTFRDERMTAVIVKDY-SRARCRHKPQQSSITTVVRSHQWDVSYAPAPNDIIWENLSVCGP--RWWLRCILLNILLFLLLFFLTTPAIIVNTM 445          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF  + +   T  F   C+F P N AFFVNY+I +AFIG   +L+RIP  ++Y+    + RS+ E   ++K+  +EFQFG  Y+W++ VFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  475 NPIVTQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLDEATIRFR--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPYFLMYMIRLCLARSAAERRNVKKHQAYEFQFGAAYAWMMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAA 690          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTK--NRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTS--QFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYN-------DFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F G+P    ++ + F++L  +F FLRK AW++GR+AL++   +RR +             L E+        T  D + Y R  SV  +    Q D G  SWL   + + D +IREK G DA  YL FQ+++I    ++ V+S+ ++LPVN  G+      N        F  TT++NL S + ++W+H + +F Y    +  +    + +     +    TL I GI K +   S I  HF++AY  C + D +  +N+ KL+ L  +R+ A  ++       +   I   + PK CG    CCI    E+ + ++YY      L+ + +KE  K   K +G+AFVTF+    A  +L+D+++     C     P++S  S+ + +  WT+SYAP    + WE+L      W ++  +IN  LF+ LF LTTP   ++ +
Sbjct:   33 FGGVPTVLALDFMCFLVLLCVFSFLRKVAWDYGRLALVSDADSRRNKHYQR---------LDEQEYVASAMQTPADSR-YERLTSVSSSVDFDQRDNGLCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDQLVETGNFENNNAYSFGRTTVVNLKSGNHLLWLHTIFAFFYLLLTVYSMRRHTSKMHYKEDDLVKRTLFISGIAKYAE-ESEIKQHFEKAYENCVVLDARICYNVAKLMSLESERKKAERSKKFYTDLMSREHIPTMINPKPCGHL-CCCIIKGCEQEEAVNYYTKLEAKLKEEYRKEREKVNTKPLGMAFVTFQNEAMAALILKDFNACQCHGCHCRRQPKSSPFSSQLHTYNWTVSYAPDPQNVYWEHLSISGLNWWVRCFVINCFLFLLLFFLTTPAIIISTM 461          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF  + +   T  F   C+F P N AFFVNY+I +AFIG   +L+RIP  ++Y+    + RS+ E   ++K+  +EFQFG  Y+W++ VFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  461 NPIVTQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLDEATIRFR--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPYFLMYMIRLCLARSAAERRNVKKHQAYEFQFGAAYAWMMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAA 676          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYN-------DFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F G+P    ++ + F++L  +F FLRK AW++GR+AL++     +  S    +        +     + S +FD++               D G  SWL   + + D +IREK G DA  YL FQ+++I    ++ V+S+ ++LPVN  G+      N        F  TT++NL S + ++W+H + +F Y    +  +    + +     +    TL I GI K +   S I  HF++AY  C + D +  +N+ KL+ L  +R+ A  ++       +   I   + PK CG    CCI    E+ + ++YY      L+ + +KE  K   K +G+AFVTF+    A  +L+D+++     C     P++S  S+ + +  WT+SYAP    + WE+L      W ++  +IN  LF+ LF LTTP   ++ +
Sbjct:   33 FGGVPTVLALDFMCFLVLLCVFSFLRKVAWDYGRLALVS-----DADSVASAMQTPADSRYERLTSVSSSVDFDQR---------------DNGLCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDQLVETGNFENNNAYSFGRTTVVNLKSGNHLLWLHTIFAFFYLLLTVYSMRRHTSKMHYKEDDLVKRTLFISGIAKYAE-ESEIKQHFEKAYENCVVLDARICYNVAKLMSLESERKKAERSKKFYTDLMSREHIPTMINPKPCGHL-CCCIIKGCEQEEAVNYYTKLEAKLKEEYRKEREKVNTKPLGMAFVTFQNEAMAALILKDFNACQCHGCHCRRQPKSSPFSSQLHTYNWTVSYAPDPQNVYWEHLSISGLNWWVRCFVINCFLFLLLFFLTTPAIIISTM 447          

Query: 1430 VEFSIKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLA 2092
            V + ++K+  N V+ +FLP+F++W  S  LPF+VYYS     HWT++ E+   + K Y FL+ MV++LPSLG+ SL  F  WLF I  +      F   C+F P N AFFVNY+ITA+ IGT  EL+R P L +Y     + R+  +   +++N  +EFQFGL Y+W  CVF+V + YS  CP+IVPFGLIY++ K+  DRYNIY+AY  + ++  +H+ A
Sbjct:  459 VTYPVEKLR-NPVITQFLPTFLLWMFSVCLPFLVYYSAFFECHWTRSSENQHTMHKCYFFLVFMVIVLPSLGLTSLNLFFRWLFDIHFLDEANIKFQ--CVFLPNNGAFFVNYVITASLIGTAMELLRFPGLTVYAARLCLARTEPDRLHVKRNQAYEFQFGLEYAWTTCVFSVVMAYSITCPVIVPFGLIYMLLKHMTDRYNIYYAYIPTKLSPGLHKAA 676          

Query:   57 YRLLDNEINVMSKATPVCDRVNIYRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRK--EQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNE-AIRQYANTGIRRTMVPKFCGRF---HSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            YR      + +S   PV +    Y+  + + V+ G  F GIP    IN + +++L ++F  LRK AW++GR+ALL  N     ++  T Y++  ++   E +E E++              S  + +++ D G  SWL   Y + D++I+ K G+DA  YL +Q++L+     +  IS+ +ILPVN  G+        F  TTI+N+ +  + +W+H+V + +YF   +  + H  ++L     ++ + TL+I  IP E S  S+   HF EAYP C + D+QF +++R L+ L+ +R  A+  +   A R      I+  + P  C R      C  ++V+   YY +    L  +   E  +   K++G  FVTF+       +++DY+   C     PQ S+++  +KS  W + YAP  + I WENL
Sbjct:    5 YRTESPLGDSLSMDPPVNETEQCYKAHSHSTVLQGLPFGGIPTVLAINFLAWLVLLLIFSCLRKAAWDYGRLALLIDNDSHALQRRWTSYDL-TSLFYGEPSEKEKSPC----------EISPSEASTK-DVGLCSWLSSIYQMKDEEIQSKCGSDAITYLSYQRHLLVVLLAVCCISVAIILPVNFSGDMLGDSPAQFGRTTIVNVPTKDRFLWLHSVFALVYFLFSVLCMRHHTSSLHYKEDDKVARTLMITKIPSEISDASLFTKHFHEAYPSCTVTDVQFCYDVRHLMKLDKERRRAMKGRMYFAGRAQKEGKIQIKIHP--CARLCPCDCCGFQQVEAEQYYGELEERLTDEFTAERNRITLKRLGAVFVTFQDERMTAVIIKDYNRLPCH--RAPQQSSVTPLLKSHKWKVHYAPAPSDIIWENL 419          

Query: 1430 VEFSIKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLA 2092
            V + ++K+  N V+ +FLP+F++W  S  LPF+VYYS     HWT++ E+   + K Y FL+ MV++LPSLG+ SL  F  WLF I  +      F   C+F P N AFFVNY+ITA+ IGT  EL+R P L +Y     + R+  +   +++N  +EFQFGL Y+W  CVF+V + YS  CP+IVPFGLIY++ K+  DRYNIY+AY  + ++  +H+ A
Sbjct:  448 VTYPVEKLR-NPVITQFLPTFLLWMFSVCLPFLVYYSAFFECHWTRSSENQHTMHKCYFFLVFMVIVLPSLGLTSLNLFFRWLFDIHFLDEANIKFQ--CVFLPNNGAFFVNYVITASLIGTAMELLRFPGLTVYAARLCLARTEPDRLHVKRNQAYEFQFGLEYAWTTCVFSVVMAYSITCPVIVPFGLIYMLLKHMTDRYNIYYAYIPTKLSPGLHKAA 665          

Query:   57 YRLLDNEINVMSKATPVCDRVNIYRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNE-AIRQYANTGIRRTMVPKFCGRF---HSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            YR      + +S   PV +    Y+  + + V+ G  F GIP    IN + +++L ++F  LRK AW++GR+ALL  N          +   ++   E +E E++              S  + +++ D G  SWL   Y + D++I+ K G+DA  YL +Q++L+     +  IS+ +ILPVN  G+        F  TTI+N+ +  + +W+H+V + +YF   +  + H  ++L     ++ + TL+I  IP E S  S+   HF EAYP C + D+QF +++R L+ L+ +R  A+  +   A R      I+  + P  C R      C  ++V+   YY +    L  +   E  +   K++G  FVTF+       +++DY+   C     PQ S+++  +KS  W + YAP  + I WENL
Sbjct:    5 YRTESPLGDSLSMDPPVNETEQCYKAHSHSTVLQGLPFGGIPTVLAINFLAWLVLLLIFSCLRKAAWDYGRLALLIDN----------DSLTSLFYGEPSEKEKSPC----------EISPSEASTK-DVGLCSWLSSIYQMKDEEIQSKCGSDAITYLSYQRHLLVVLLAVCCISVAIILPVNFSGDMLGDSPAQFGRTTIVNVPTKDRFLWLHSVFALVYFLFSVLCMRHHTSSLHYKEDDKVARTLMITKIPSEISDASLFTKHFHEAYPSCTVTDVQFCYDVRHLMKLDKERRRAMKGRMYFAGRAQKEGKIQIKIHP--CARLCPCDCCGFQQVEAEQYYGELEERLTDEFTAERNRITLKRLGAVFVTFQDERMTAVIIKDYNRLPCH--RAPQQSSVTPLLKSHKWKVHYAPAPSDIIWENL 408          

Query: 1430 VEFSIKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLA 2092
            V + ++K+  N V+ +FLP+F++W  S  LPF+VYYS     HWT++ E+   + K Y FL+ MV++LPSLG+ SL  F  WLF I  +      F   C+F P N AFFVNY+ITA+ IGT  EL+R P L +Y     + R+  +   +++N  +EFQFGL Y+W  CVF+V + YS  CP+IVPFGLIY++ K+  DRYNIY+AY  + ++  +H+ A
Sbjct:  444 VTYPVEKLR-NPVITQFLPTFLLWMFSVCLPFLVYYSAFFECHWTRSSENQHTMHKCYFFLVFMVIVLPSLGLTSLNLFFRWLFDIHFLDEANIKFQ--CVFLPNNGAFFVNYVITASLIGTAMELLRFPGLTVYAARLCLARTEPDRLHVKRNQAYEFQFGLEYAWTTCVFSVVMAYSITCPVIVPFGLIYMLLKHMTDRYNIYYAYIPTKLSPGLHKAA 661          

Query:   57 YRLLDNEINVMSKATPVCDRVNIYRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNE-AIRQYANTGIRRTMVPKFCGRF---HSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            YR      + +S   PV +    Y+  + + V+ G  F GIP    IN + +++L ++F  LRK AW++GR+ALL  N          +   ++   E +E E++       +     AS  D T   + GF     FF    D++I+ K G+DA  YL +Q++L+     +  IS+ +ILPVN  G+        F  TTI+N+ +  + +W+H+V + +YF   +  + H  ++L     ++ + TL+I  IP E S  S+   HF EAYP C + D+QF +++R L+ L+ +R  A+  +   A R      I+  + P  C R      C  ++V+   YY +    L  +   E  +   K++G  FVTF+       +++DY+   C     PQ S+++  +KS  W + YAP  + I WENL
Sbjct:    5 YRTESPLGDSLSMDPPVNETEQCYKAHSHSTVLQGLPFGGIPTVLAINFLAWLVLLLIFSCLRKAAWDYGRLALLIDN----------DSLTSLFYGEPSEKEKSPC-----EISPSEASTKDVT---NCGFL----FF---RDEEIQSKCGSDAITYLSYQRHLLVVLLAVCCISVAIILPVNFSGDMLGDSPAQFGRTTIVNVPTKDRFLWLHSVFALVYFLFSVLCMRHHTSSLHYKEDDKVARTLMITKIPSEISDASLFTKHFHEAYPSCTVTDVQFCYDVRHLMKLDKERRRAMKGRMYFAGRAQKEGKIQIKIHP--CARLCPCDCCGFQQVEAEQYYGELEERLTDEFTAERNRITLKRLGAVFVTFQDERMTAVIIKDYNRLPCH--RAPQQSSVTPLLKSHKWKVHYAPAPSDIIWENL 404          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIH 2083
            N V+++F P+ ++W+ S LLP IVYYS ++  HWTK+ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF  + + L        C+F P   AFFVNY+I +AF+G   EL+R+P LI+Y    I+ +S+ E   I++N  +E++FG  Y+W+LCVFTV + YS  CP+IVPFGLIY++ K+ VDR+N+Y+AY  + ++ KIH
Sbjct:  459 NPVISQFFPTLMLWSFSALLPTIVYYSTLLEAHWTKSAENRIMMHKVYIFLIFMVLILPSLGLTSLDFFFRWLFD-RALDLQG-PVRLECVFLPDQGAFFVNYVIASAFVGNGMELMRLPGLILYTIRMIMAKSAAERRNIKQNQAFEYEFGAMYAWMLCVFTVVMAYSITCPIIVPFGLIYLLLKHMVDRHNLYYAYLPTKLDKKIH 664          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYND-EILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCS---LLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F GIP    +++  F+ L + F  +R++ W++GR+AL+      +  S+ ++ +  ++ S   E  E D+                       GF  W+   + ++D+DI ++ G DA  YL FQ+++I    I +++S+ VILPVN+ GN        F  TTI NL  + +++W+H V++ +Y    +  + H  + ++    N    TL I G+P+     ++ L HF EAYP C ++++   +++  LI L+ +R+ A             TG R  + PK CG+F  CC+    E  D I+YY      ++E   +K+ V   D  +G+ FVTF     +  +L+D+++  CS     +  Q SA S  + ++ W ++YA     I W NL     KW  + + IN  LFI LF LTTP+  ++ +
Sbjct:   46 FGGIPTVLVLDVACFMFLLLAFAIIRRHFWDYGRVALV-----YDADSSPHSRYRRLSSSSGGEELERDN-----------------------GFCYWMTSTFQMNDEDIYDRCGEDATHYLSFQRHIICLLIIASILSVGVILPVNLSGNLLDKDPLSFGRTTIANLQHHDRLLWLHTVVAVVYLILTVVFMRHHLSAIKYKEENTVKQTLFITGLPRNVDKETVRL-HFSEAYPSCQVEEVNLCYDVADLIRLSKERKKAEKNLAYFTNLLNKTGRRVLINPKPCGQF-CCCVVRGCEREDAIEYYTRVRDGVMEEYARKQEVVC-DIPLGIVFVTFADKSMSTLILKDFNAVKCSGYRCAHETQPSAYSKQLGTSRWGVTYATYPENICWGNLSLQGVKWWARCLGINFCLFIVLFFLTTPSIIISTM 445          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIH 2083
            N V+++F P+ ++W+ S LLP IVYYS ++  HWTK+ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF  + + L        C+F P   AFFVNY+I +AF+G   EL+R+P LI+Y    I+ +S+ E   I++N  +E++FG  Y+W+LCVFTV + YS  CP+IVPFGLIY++ K+ VDR+N+Y+AY  + ++ KIH
Sbjct:  446 NPVISQFFPTLMLWSFSALLPTIVYYSTLLEAHWTKSAENRIMMHKVYIFLIFMVLILPSLGLTSLDFFFRWLFD-RALDLQG-PVRLECVFLPDQGAFFVNYVIASAFVGNGMELMRLPGLILYTIRMIMAKSAAERRNIKQNQAFEYEFGAMYAWMLCVFTVVMAYSITCPIIVPFGLIYLLLKHMVDRHNLYYAYLPTKLDKKIH 651          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI---EEVDVIDYYND-EILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCS---LLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F GIP    +++  F+ L + F  +R++ W++GR+AL+    R   +   Y                                V+ T   F            + SD+DI ++ G DA  YL FQ+++I    I +++S+ VILPVN+ GN        F  TTI NL  + +++W+H V++ +Y    +  + H  + ++    N    TL I G+P+     ++ L HF EAYP C ++++   +++  LI L+ +R+ A             TG R  + PK CG+F  C +   E  D I+YY      ++E   +K+ V   D  +G+ FVTF     +  +L+D+++  CS     +  Q SA S  + ++ W ++YA     I W NL     KW  + + IN  LFI LF LTTP+  ++ +
Sbjct:   46 FGGIPTVLVLDVACFMFLLLAFAIIRRHFWDYGRVALVYDADRYVIAQIPYA-----------------------------THVLPTVCPF------------LSSDEDIYDRCGEDATHYLSFQRHIICLLIIASILSVGVILPVNLSGNLLDKDPLSFGRTTIANLQHHDRLLWLHTVVAVVYLILTVVFMRHHLSAIKYKEENTVKQTLFITGLPRNVDKETVRL-HFSEAYPSCQVEEVNLCYDVADLIRLSKERKKAEKNLAYFTNLLNKTGRRVLINPKPCGQFCCCVVRGCEREDAIEYYTRVRDGVMEEYARKQEVVC-DIPLGIVFVTFADKSMSTLILKDFNAVKCSGYRCAHETQPSAYSKQLGTSRWGVTYATYPENICWGNLSLQGVKWWARCLGINFCLFIVLFFLTTPSIIISTM 432          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N V+++F P+ ++W+ S LLP IVYYS ++  HWT++ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF   + + +       C+F P   AFFVNY+I +AFIG+  EL+R+P LI+Y +  I+ +++ +   +++N  +E++FG  Y+W+LCVFTV + YS  CP+IVPFGLIYI+ K+ VDR+N+YFAY  + +  +IH  A++  + A
Sbjct:  459 NPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSETS---IRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAA 673          

Query:   90 SKATPVCDRVNIYRITNDT---------AVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKN------RRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI---EEVDVIDYY---NDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLL---NYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            SKA  V +R+ +    ND+          V+ G  F GIP    +++  F+ L ++F  +R+  W++GRIAL+++       +R   SS+G          +  ENE                           G   WL   + + D  I E  G DA  YL FQ+++IF   +I+ +SL VILPVN+ G+        F  TTI NL + + ++W+H V S +Y F  +  +WH   +++    +    TL I G+P+E+     +  HF++AYP C + D+Q  +++ KLI+L  +R+    +        A TG R  + PK CG+F  C +   E  D I YY   ND +L    +   E  +  D+ +G+AFVTF     A  +L+D+++  C  L     PQ S+ S ++  + WT+++A     I W+NL     +W ++ + IN  LF+ LF LTTP+  ++ +
Sbjct:   12 SKAVFVRERLGLGERPNDSYCYNSAKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSEAGSEARFQRLSSSSSG---------QQDFENE--------------------------LGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREAR-KETVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTYYTNLQAKTGRRTLINPKPCGQFCCCEVQGCEREDAISYYTRMNDSLL---ERITAEESRVQDQPLGMAFVTFREKSMATYILKDFNACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTM 445          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N V+++F P+ ++W+ S LLP IVYYS ++  HWT++ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF   + + +       C+F P   AFFVNY+I +AFIG+  EL+R+P LI+Y +  I+ +++ +   +++N  +E++FG  Y+W+LCVFTV + YS  CP+IVPFGLIYI+ K+ VDR+N+YFAY  + +  +IH  A++  + A
Sbjct:  459 NPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSETS---IRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAA 673          

Query:   90 SKATPVCDRVNIYRITNDT---------AVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKN------RRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI---EEVDVIDYY---NDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLL---NYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            SKA  V +R+ +    ND+          V+ G  F GIP    +++  F+ L ++F  +R+  W++GRIAL+++       +R   SS+G          +  ENE                           G   WL   + + D  I E  G DA  YL FQ+++IF   +I+ +SL VILPVN+ G+        F  TTI NL + + ++W+H V S +Y F  +  +WH   +++    +    TL I G+P+E+     +  HF++AYP C + D+Q  +++ KLI+L  +R+    +        A TG R  + PK CG+F  C +   E  D I YY   ND +L    +   E  +  D+ +G+AFVTF     A  +L+D+++  C  L     PQ S+ S ++  + WT+++A     I W+NL     +W ++ + IN  LF+ LF LTTP+  ++ +
Sbjct:   12 SKAVFVRERLGLGERPNDSYCYNSAKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSEAGSEARFQRLSSSSSG---------QQDFENE--------------------------LGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREAR-KETVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTYYTNLQAKTGRRTLINPKPCGQFCCCEVQGCEREDAISYYTRMNDSLL---ERITAEESRVQDQPLGMAFVTFREKSMATYILKDFNACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTM 445          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF  + +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+    + RS+ E   ++++  +EFQFG  Y+W++CVFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  + ++ KIH  A++  V A
Sbjct:  472 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAA 687          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLT---KNRRKEQSSTGYNIWNTVTLSEKNENEETDST-EFDEKTYLRRASVIDTTSQFDK---GFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCC-----IEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYH----SSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            F G+P    ++ + F+ L  LF  LRK AW++GR+AL+T   + RR+E+              E+ E E   S    D      R + + ++  FD+   GF SWL   + + D +IR+K G DA  YL FQ+++I    ++ V+S+ ++LPVN  G+  +     F  TTI NL S + ++W+H   +FLY    +  +    + ++    +    TL I+GI K +     I  HF+EAYP C + + +  +N+ +L+ L+ +R+ A   +       +   +   + PK CG  H CC      E+V+ I+YY      L+   ++E  K  +K +G+AFVTF        +L+D++      C+    P+ S+ S  +  + WT++YAP    I WE+L
Sbjct:   38 FGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQER--------------ERVEQEYVASAMHGDSHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAE-SEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPAMINPKPCG--HLCCCVVRGCEQVEAIEYYTKLEQRLKEDYRREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRASSCSEALHISNWTVTYAPDPQNIYWEHL 423          

Query: 1442 IKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            I+K+   IV  +F PS ++WA +  +P +VY S  +  HWT++ ++  ++ K Y FL+ MV+ILPS+G+ SL  F+ WLF I  ++  T  F   C+F P N AFF+NY+ITAA +GT  EL+R+  L  Y     + +S  E   IRKN   +FQFG  Y+W+L VF+V + YS  CP+IVPFGL+Y+  K+  DRYN+Y++Y  + +N++IH  A+   +FA
Sbjct:  441 IEKLQSPIV-TQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQ--CVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLNAQIHMAAVYQAIFA 661          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYND-FATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKF-CGRFHSC----CIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDY-HSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            F GIP    +NI+ ++ + +L+ FLRK AW++GR+ALL  N          +   ++   E++E         + +   RR          D+GF SW      + D+D+  K G+DA  Y+ FQ +LI    I+ + SL +ILPVN    GT + +N  F  TTI+N+S+ S+ +W+H++ +FLYF   +A + H             + TL+I  +P E     II  HF EAYP C +  + F +++R LI L+ QR  A+  +     +   TG  + M+    C R   C    C +EVD   YY++    L  +   E+ +   K++ + FVTF+     R++ +DY +  C    +P+ S+++  +K+ +W +++AP    I W++L
Sbjct:   33 FGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHN----------DSLTSLIYGEQSEKSSPSEVSLEAE---RR----------DRGFSSWFFNSLTMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNY--IGTVLDWNSHFGRTTIVNVSTESKFLWLHSLFAFLYFLINLAFMGHHCLGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMRGRLYYTAKAKKTG--KVMIKTHPCSRLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVQLKRLDLIFVTFQDARTVRRIYDDYKYIHCG--RHPKQSSVTTIVKNYHWRVAHAPHPKDIIWKHL 397          

Query: 1442 IKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            I+K+   IV  +F PS ++WA +  +P +VY S  +  HWT++ ++  ++ K Y FL+ MV+ILPS+G+ SL  F+ WLF I  ++  T  F   C+F P N AFF+NY+ITAA +GT  EL+R+  L  Y     + +S  E   IRKN   +FQFG  Y+W+L VF+V + YS  CP+IVPFGL+Y+  K+  DRYN+Y++Y  + +N++IH  A+   +FA
Sbjct:  441 IEKLQSPIV-TQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQ--CVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLNAQIHMAAVYQAIFA 661          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYND-FATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKF-CGRFHSC----CIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDY-HSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL 1322
            F GIP    +NI+ ++ + +L+ FLRK AW++GR+ALL  N          +   ++   E++E         + +   RR          D+GF SW      + D+D+  K G+DA  Y+ FQ +LI    I+ + SL +ILPVN    GT + +N  F  TTI+N+S+ S+ +W+H++ +FLYF   +A + H             + TL+I  +P E     II  HF EAYP C +  + F +++R LI L+ QR  A+  +     +   TG  + M+    C R   C    C +EVD   YY++    L  +   E+ +   K++ + FVTF+     R++ +DY +  C    +P+ S+++  +K+ +W +++AP    I W++L
Sbjct:   33 FGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHN----------DSLTSLIYGEQSEKSSPSEVSLEAE---RR----------DRGFSSWFFNSLTMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNY--IGTVLDWNSHFGRTTIVNVSTESKFLWLHSLFAFLYFLINLAFMGHHCLGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMRGRLYYTAKAKKTG--KVMIKTHPCSRLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVQLKRLDLIFVTFQDARTVRRIYDDYKYIHCG--RHPKQSSVTTIVKNYHWRVAHAPHPKDIIWKHL 397          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N V+ +F P+ ++WA S LLPFIVYYS     HWT++ E+   + K +  L+ MV+ILPSLG++SL  F  WLF ++ +      F   C+F P N AFFVNY+IT++ IGT  EL+RIP L++Y       +S  E   ++ +  +EFQFGL Y+W +C+F+V++TYS  CP+IVPFGL+Y++ K+ VDRYNIY+AY  + +N +IH  A+S  V A
Sbjct:  463 NPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQ--CVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVA 678          

Query:  126 YRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKF-CGRFHSCCI---EEVDVIDYYN--DEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENL--CHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            YR  + ++V+ G  F G+P    IN+V ++IL ++F  LRK AW++GR+ALL KN          +   ++   E++E E+T S      +  +           D GF SWL   Y + D++IR K G DA  YL FQ+++I    ++ ++SL +ILPVN+ GN       +F  TT++N+ + +  +W+H++ + LYF   +  + H ++ L+     + + TL+I  IP+E S   +I  H  EAYP C + DI F  N++KL+ L+ +R  A+  +     +    G  R M+    C +   C I   E+VD   YY+  +E L  E   +K  +    K++G+AFVTF        +++DY S     + PQ S+++  ++S  W +SYAP  N I WENL  C P  +W ++ IL+N +LF+ LF LTTP   +N +
Sbjct:   34 YRSHSRSSVLQGLPFGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKN----------DSLTSLFYGEQSEKEKTPSDSSPSDSETK-----------DMGFCSWLTSLYHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLGDNPENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLYFTTKAQKNG--RIMIKTHPCAQIFCCDICGFEKVDAEQYYSELEEKLTDEFNAEKNWISM--KRLGIAFVTFRDERMTAVIVKDY-SRARCRHKPQQSSITTVVRSHQWDVSYAPAPNDIIWENLSVCGP--RWWLRCILLNILLFLLLFFLTTPAIIVNTM 449          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N V+++F P+ ++W+ S LLP IVYYS ++  HWT++ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF   + + +       C+F P   AFFVNY+I +AFIG+  EL+R+P LI+Y +  I+ +++ +   +++N  +E++FG  Y+W+LCVFTV + YS  CP+IVPFGLIYI+ K+ VDR+N+YFAY  + +  +IH  A++  + A
Sbjct:  459 NPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSETS---IRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAA 673          

Query:   90 SKATPVCDRVNIYRITNDT---------AVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKN------RRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI---EEVDVIDYY---NDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLL---NYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            SKA  V +R+ +    ND+          V+ G  F GIP    +++  F+ L ++F  +R+  W++GRIAL+++       +R   SS+G          +  ENE                           G   WL   + + D  I E  G DA  YL FQ+++IF   +I+ +SL VILPVN+ G+        F  TTI NL + + ++W+H V S +Y F  +  +WH   +++    +    TL I G+P+E+     +  HF++AYP C + D+Q  +++ KLI+L  +R+    +        A TG R  + PK CG+F  C +   E  D I YY   ND +L    +   E  +  D+ +G+AFVTF     A  +L+D+++  C  L     PQ S+ S ++  + WT+++A     I W+NL     +W ++ + IN  LF+ LF LTTP+  ++ +
Sbjct:   12 SKAVFVRERLGLGERPNDSYCYNSAKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSEAGSEARFQRLSSSSSG---------QQDFENE--------------------------LGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREAR-KETVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTYYTNLQAKTGRRTLINPKPCGQFCCCEVQGCEREDAISYYTRMNDSLL---ERITAEESRVQDQPLGMAFVTFREKSMATYILKDFNACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTM 445          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++++F P+ ++W+ S LLP IVYYS ++  HWTK+ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF   + + +       C+F P   AFFVNY+I +AFIG   EL+R+P LI+Y +  I+ +++ +   +++N  ++++FG  Y+W+LCVFTV V YS  CP+I PFGLIYI+ K+ VDR+N+YF Y  + +   IH  A++  + A
Sbjct:  460 NPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEAS---IRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKGIHFAAVNQALAA 674          

Query:  111 DRVN---IYRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFD----KGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEV-----DVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLL---NYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIK 1352
            DR N    Y    ++ V+ G  F GIP    I++  F+ L ++F  +R+  W++GRIAL++                                E D ++  +R S   ++ Q D     G   WL   + + D  I E  G DA  YL FQ+++IF   +++ +SL VILPVN+ G+        F  TTI NL + + ++W+H + + +Y F  +  + H   +++    N    TL I G+P+++     +  HF++AYP C + D+Q  +N+ KLI+L  +++    +          TG R  + PK CG+F  CC E +     D I YY      L  +  +E     D+ +G+AFVTF+    A  +L+D+++  C  L     PQ S+ S ++ ++ WT+++A     I W+NL     +W ++
Sbjct:   25 DRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVS--------------------------------EADSESRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFLTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDAR-KETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLINPKPCGQF--CCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQ 421          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++++F P+ ++W+ S LLP IVYYS ++  HWTK+ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF   + + +       C+F P   AFFVNY+I +AFIG   EL+R+P LI+Y +  I+ +++ +   +++N  ++++FG  Y+W+LCVFTV + YS  CP+I PFGLIYI+ K+ VDR+N+YF Y  + +   IH  A++  + A
Sbjct:  460 NPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEAS---IRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIMAYSITCPIIAPFGLIYILLKHMVDRHNLYFIYLPAKLEKGIHFAAVNQALAA 674          

Query:  111 DRVN---IYRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFD----KGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEV---DVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-SCSLL---NYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIK 1352
            DR N    Y    ++ V+ G  F GIP    I++  F+ L ++F  +R+  W++GRIAL++                                E D +   +R S   ++ Q D     G   WL   + + D  I E  G DA  YL FQ+++IF   +++ +SL VILPVN+ G+        F  TTI NL + + ++W+H + + +Y F  +  + H   +++    N    TL I G+P+++     +  HF++AYP C + D+Q  +N+ KLI+L  +R+    +          TG R  + PK CG+F  C ++     D I YY      L  +  +E     D+ +G+AFVTF+    A  +L+D+++  C  L     PQ S+ S ++ ++ WT+++A     I W+NL     +W ++
Sbjct:   25 DRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVS--------------------------------EADSEPRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFLTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDAR-KETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKERKKTEKSLTYYTNLQVKTGQRTLINPKPCGQFCCCEVQGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQ 421          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            + ++++F P+ ++W+ S LLP IV YS ++  HWTK+ E+  ++ K Y FLI MVLILPSLG+ SL  F  WLF   + + +       C+F P   AFFVNY+I +AFIG   EL+R+P LI+Y +  ++ +++ +   ++++  +E++FG  Y+W+LCVFTV + YS  CP+IVPFGLIYI+ K+ VDR+N+YFAY  + +  +IH  A++  + A
Sbjct:  459 DPIISQFFPTLLLWSFSALLPTIVCYSTLLESHWTKSGENRIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEAS---IRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMVMAKTAADRRNVKQHQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAA 673          

Query:  126 YRITNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI---EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSS-CSLL---NYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            Y    ++ V+ G  F GIP    I++  F+ L V+F  +R+  W++GRIAL+++              N+ +   +  +  +   +F+ +                 G  SWL   + + D  I E  G DA  YL FQ+++IF   +++ +SL +ILPVN+ G+        F  TTI NL + + ++W+H + + LY    +  + H   +++    +    TL + G+PK++     +  HF++AYP C + ++Q  +N+ KLI+L  +R+    +          TG R  + PK CG+F  C +   E  D I YY      L  +  +E  +  D+ +G+AFVTF+    A  +L+D+++  C  L     PQ S+ S ++  + W++++A     I W+NL     +W  + + IN ILF+ LF LTTP+  L+ +
Sbjct:   33 YNSAKNSTVLQGVTFGGIPTVLFIDVSCFLFLIVVFSIIRRKFWDYGRIALVSEG-------------NSESRFRRLSSSSSGQQDFESEL----------------GCCSWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSCLSLCIILPVNLSGDLLDKDPYSFGRTTIANLQTDNNLLWLHTIFAILYLILTVVFMRHHTQSIKYKEESLVRRTLFVTGLPKDAK-KETVESHFRDAYPTCEVVEVQLCYNVAKLIYLCKERKKTEKSLTYYTNLQVKTGQRTFINPKPCGQFCCCEVRGCEWEDAISYYTRMKDRLMERITEEECRVQDQPLGMAFVTFQEKSMATYILKDFNACKCQGLQCKGEPQPSSHSRELGISRWSVTFAAYPEDICWKNLSIQGFRWWFQWLGINFILFVGLFFLTTPSIILSTM 445          

Query:   90 SKATPVCDRVNIYRITNDTAVIYGFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKE---QSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGN--GTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL-QLNFQSKK 1451
            S  +P C+ V  Y  +    +   + GIP    IN+V F+ L +LF  LRK AW++GR+AL+ +   KE   +  +GYN+W ++   +++    T S E  + T          TSQ DKG F W+  F+ + D DI  K G DA QYL FQ+YL+    IITV+S+ VILP+N  G+  GT     DF  TTI NL S   ++WVHAV++ +Y   +I ++ HF   L +    + S TL++  IPK   F S IL HF+EAYP+  + DIQFA+++  L+ L+  R+ A  A+      Y  TG R  M P  CG+   CC  EVD I++Y  E   L+  C++E   AY   +G+AF+T  +   A+++  D+ +SC   + PQ S+L  +++   W + +AP    I+WENL  P  +W   AI IN +L + LF LTTP   L+ L  LN   KK
Sbjct:   12 SNESPNCEEVARYGNSTHVFLYDKYNGIPDTLIINLVVFVCLLLLFTILRKIAWDYGRLALVNRTEEKEAIRKGRSGYNVWTSLFFGDRDRRSFTGSQESLDTT---------VTSQ-DKGMFRWIVAFWRLRDVDILNKCGRDAIQYLSFQRYLLVYISIITVLSVGVILPLNFQGSLLGTSA---DFGHTTIGNLESNDPILWVHAVMAVVYLVIVIGVLSHFRLNLDVEEDEQVSRTLMVSNIPKHKCFHSTILQHFEEAYPEANVTDIQFAYDIAGLVLLDKHRKRAAEAKQFCENIYKTTGQRPMMRPVICGQI-CCCCAEVDAINFYQAEEAELKKACEEEKETAYQTPLGIAFITLASESQAQRIRTDFRASCKGTHNPQMSSLYQELQVQNWIMHFAPSPESIHWENLSVPDWRWWTTAICINGVLIVLLFFLTTPIMFLHTLDMLNIDIKK 457          

Query: 1439 SIKKISMNI---VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFXXXXXXXXXXXXVNKVKSNLVYIFVXXXXXXXXXXXXXXXXYGWFTQVK 2263
             IKK   N+    L +FLP+ ++W  S LLP IVY+S+ +IGHWTKT EH A++ KT+ F++ MVLILPSLG+ S  +   W+     +   T    W CIF PGN +FFVNYIIT+AFIG   EL+R  EL IY    +  RS  E   +RK+V+W+FQ+G+ Y+W+LC+  + V+YS  CPL+ PFGLIY++FK+ VDRYNI+FAY  S IN  IH  A++F ++A +LLQ N++ +  +     + V+IF  ++  ++L +F+    +GWF  ++
Sbjct:  454 DIKKPVENLHSAYLVQFLPTLLLWIFSALLPSIVYWSDQIIGHWTKTAEHHAIMRKTFIFILFMVLILPSLGLTSAKALFEWI-----VMSKTRSLQWQCIFLPGNGSFFVNYIITSAFIGAALELLRFSELFIYGVKLLFARSVAERAAVRKSVLWDFQYGVQYAWMLCMVAIIVSYSIPCPLVTPFGLIYLLFKHVVDRYNIFFAYNSSRINKHIHGSAVTFVLWAVILLQFNVVFFTGLRAEGFDPVFIFSCVALFITLIIFVGRISFGWFKHLR 726          

Query:   90 SKATPVCDRVNIYRITNDTAVIYGFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKN----------RRKE-----QSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGN--GTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL-QLNFQSKK 1451
            S  +P C+ V  Y  +    +   + GIP    IN+V F+ L +LF  LRK AW++GR+AL+ +           RR +     +  +GYN+W ++   +++    T S E  + T          TSQ DKG F W+  F+ + D DI  K G DA QYL FQ+YL+    IITV+S+ VILP+N  G+  GT     DF  TTI NL S   ++WVHAV++ +Y   +I ++ HF   L +    + S TL++  IPK   F S IL HF+EAYP+  + DIQFA+++  L+ L+  R+ A  A+      Y  TG R  M P  CG+   CC  EVD I++Y  E   L+  C++E   AY   +G+AF+T  +   A+++  D+ +SC   + PQ S+L  +++   W + +AP    I+WENL  P  +W   AI IN +L + LF LTTP   L+ L  LN   KK
Sbjct:   12 SNESPNCEEVARYGNSTHVFLYDKYNGIPDTLIINLVVFVCLLLLFTILRKIAWDYGRLALVNRTEENDGVPLVVRRPKVEAIRKGRSGYNVWTSLFFGDRDRRSFTGSQESLDTT---------VTSQ-DKGMFRWIVAFWRLRDVDILNKCGRDAIQYLSFQRYLLVYISIITVLSVGVILPLNFQGSLLGTSA---DFGHTTIGNLESNDPILWVHAVMAVVYLVIVIGVLSHFRLNLDVEEDEQVSRTLMVSNIPKHKCFHSTILQHFEEAYPEANVTDIQFAYDIAGLVLLDKHRKRAAEAKQFCENIYKTTGQRPMMRPVICGQI-CCCCAEVDAINFYQAEEAELKKACEEEKETAYQTPLGIAFITLASESQAQRIRTDFRASCKGTHNPQMSSLYQELQVQNWIMHFAPSPESIHWENLSVPDWRWWTTAICINGVLIVLLFFLTTPIMFLHTLDMLNIDIKK 469          

Query: 1439 SIKKISMNI---VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFXXXXXXXXXXXXVNKVKSNLVYIFVXXXXXXXXXXXXXXXXYGWFTQVK 2263
             IKK   N+    L +FLP+ ++W  S LLP IVY+S+ +IGHWTKT EH A++ KT+ F++ MVLILPSLG+ S  +   W+     +   T    W CIF PGN +FFVNYIIT+AFIG   EL+R  EL IY    +  RS  E   +RK+V+W+FQ+G+ Y+W+LC+  + V+YS  CPL+ PFGLIY++FK+ VDRYNI+FAY  S IN  IH  A++F ++A +LLQ N++ +  +     + V+IF  ++  ++L +F+    +GWF  ++
Sbjct:  466 DIKKPVENLHSAYLVQFLPTLLLWIFSALLPSIVYWSDQIIGHWTKTAEHHAIMRKTFIFILFMVLILPSLGLTSAKALFEWI-----VMSKTRSLQWQCIFLPGNGSFFVNYIITSAFIGAALELLRFSELFIYGVKLLFARSVAERAAVRKSVLWDFQYGVQYAWMLCMVAIIVSYSIPCPLVTPFGLIYLLFKHVVDRYNIFFAYNSSRINKHIHGSAVTFVLWAVILLQFNVVFFTGLRAEGFDPVFIFSCVALFITLIIFVGRISFGWFKHLR 738          

Query:   90 SKATPVCDRVNIYRITNDTAVIYGFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGN--GTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL-QLNFQSKK 1451
            S  +P C+ V  Y  +    +   + GIP    IN+V F+ L +LF  LRK AW++GR+AL+  NR +E+       W ++   +++    T S E  + T          TSQ DKG F W+  F+ + D DI  K G DA QYL FQ+YL+    IITV+S+ VILP+N  G+  GT     DF  TTI NL S   ++WVHAV++ +Y   +I ++ HF   L +    + S TL++  IPK   F S IL HF+EAYP+  + DIQFA+++  L+ L+  R+ A  A+      Y  TG R  M P  CG+   CC  EVD I++Y  E   L+  C++E   AY   +G+AF+T  +   A+++  D+ +SC   + PQ S+L  +++   W + +AP    I+WENL  P  +W   AI IN +L + LF LTTP   L+ L  LN   KK
Sbjct:   12 SNESPNCEEVARYGNSTHVFLYDKYNGIPDTLIINLVVFVCLLLLFTILRKIAWDYGRLALV--NRTEEK-------WTSLFFGDRDRRSFTGSQESLDTT---------VTSQ-DKGMFRWIVAFWRLRDVDILNKCGRDAIQYLSFQRYLLVYISIITVLSVGVILPLNFQGSLLGTSA---DFGHTTIGNLESNDPILWVHAVMAVVYLVIVIGVLSHFRLNLDVEEDEQVSRTLMVSNIPKHKCFHSTILQHFEEAYPEANVTDIQFAYDIAGLVLLDKHRKRAAEAKQFCENIYKTTGQRPMMRPVICGQI-CCCCAEVDAINFYQAEEAELKKACEEEKETAYQTPLGIAFITLASESQAQRIRTDFRASCKGTHNPQMSSLYQELQVQNWIMHFAPSPESIHWENLSVPDWRWWTTAICINGVLIVLLFFLTTPIMFLHTLDMLNIDIKK 445          

Query: 1439 SIKKISMNI---VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFXXXXXXXXXXXXVNKVKSNLVYIFVXXXXXXXXXXXXXXXXYGWFTQVK 2263
             IKK   N+    L +FLP+ ++W  S LLP IVY+S+ +IGHWTKT EH A++ KT+ F++ MVLILPSLG+ S  +   W+     +   T    W CIF PGN +FFVNYIIT+AFIG   EL+R  EL IY    +  RS  E   +RK+V+W+FQ+G+ Y+W+LC+  + V+YS  CPL+ PFGLIY++FK+ VDRYNI+FAY  S IN  IH  A++F ++A +LLQ N++ +  +     + V+IF  ++  ++L +F+    +GWF  ++
Sbjct:  442 DIKKPVENLHSAYLVQFLPTLLLWIFSALLPSIVYWSDQIIGHWTKTAEHHAIMRKTFIFILFMVLILPSLGLTSAKALFEWI-----VMSKTRSLQWQCIFLPGNGSFFVNYIITSAFIGAALELLRFSELFIYGVKLLFARSVAERAAVRKSVLWDFQYGVQYAWMLCMVAIIVSYSIPCPLVTPFGLIYLLFKHVVDRYNIFFAYNSSRINKHIHGSAVTFVLWAVILLQFNVVFFTGLRAEGFDPVFIFSCVALFITLIIFVGRISFGWFKHLR 714          

Query:   90 SKATPVCDRVNIYRITNDTAVIYGFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKN----------RRKE-----QSSTGY-NIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGN--GTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL-QLNFQSKK 1451
            S  +P C+ V  Y  +    +   + GIP    IN+V F+ L +LF  LRK AW++GR+AL+ +           RR +     +   G+ N+W ++   +++    T S E  + T          TSQ DKG F W+  F+ + D DI  K G DA QYL FQ+YL+    IITV+S+ VILP+N  G+  GT     DF  TTI NL S   ++WVHAV++ +Y   +I ++ HF   L +    + S TL++  IPK   F S IL HF+EAYP+  + DIQFA+++  L+ L+  R+ A  A+      Y  TG R  M P  CG+   CC  EVD I++Y  E   L+  C++E   AY   +G+AF+T  +   A+++  D+ +SC   + PQ S+L  +++   W + +AP    I+WENL  P  +W   AI IN +L + LF LTTP   L+ L  LN   KK
Sbjct:   12 SNESPNCEEVARYGNSTHVFLYDKYNGIPDTLIINLVVFVCLLLLFTILRKIAWDYGRLALVNRTEENDGVPLVVRRPKVINIWKGCMGWLNLWTSLFFGDRDRRSFTGSQESLDTT---------VTSQ-DKGMFRWIVAFWRLRDVDILNKCGRDAIQYLSFQRYLLVYISIITVLSVGVILPLNFQGSLLGTSA---DFGHTTIGNLESNDPILWVHAVMAVVYLVIVIGVLSHFRLNLDVEEDEQVSRTLMVSNIPKHKCFHSTILQHFEEAYPEANVTDIQFAYDIAGLVLLDKHRKRAAEAKQFCENIYKTTGQRPMMRPVICGQI-CCCCAEVDAINFYQAEEAELKKACEEEKETAYQTPLGIAFITLASESQAQRIRTDFRASCKGTHNPQMSSLYQELQVQNWIMHFAPSPESIHWENLSVPDWRWWTTAICINGVLIVLLFFLTTPIMFLHTLDMLNIDIKK 470          

Query: 1439 SIKKISMNI---VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFXXXXXXXXXXXXVNKVKSNLVYIFVXXXXXXXXXXXXXXXXYGWFTQVK 2263
             IKK   N+    L +FLP+ ++W  S LLP IVY+S+ +IGHWTKT EH A++ KT+ F++ MVLILPSLG+ S  +   W+     +   T    W CIF PGN +FFVNYIIT+AFIG   EL+R  EL IY    +  RS  E   +RK+V+W+FQ+G+ Y+W+LC+  + V+YS  CPL+ PFGLIY++FK+ VDRYNI+FAY  S IN  IH  A++F ++A +LLQ N++ +  +     + V+IF  ++  ++L +F+    +GWF  ++
Sbjct:  467 DIKKPVENLHSAYLVQFLPTLLLWIFSALLPSIVYWSDQIIGHWTKTAEHHAIMRKTFIFILFMVLILPSLGLTSAKALFEWI-----VMSKTRSLQWQCIFLPGNGSFFVNYIITSAFIGAALELLRFSELFIYGVKLLFARSVAERAAVRKSVLWDFQYGVQYAWMLCMVAIIVSYSIPCPLVTPFGLIYLLFKHVVDRYNIFFAYNSSRINKHIHGSAVTFVLWAVILLQFNVVFFTGLRAEGFDPVFIFSCVALFITLIIFVGRISFGWFKHLR 739          

Query:   81 NVMSKATPVCDRVNIYRITNDTAVIY--------------GFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSS--TGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINE-ASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI-----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVLQL 1433
            N  S+A      V I R  ND+   Y              G+EGIPQN TIN++ +I L +LF  LRKNAWN+GR+ALL +  R+E +   + YNIW  +    + E+ + DS         + A   D  S +D G FSW+   + + D  IR K G+DA QYL FQ+++I    I  V+SL + LP+NM G+  K     F  TT+ NL   S  +W+H  LS L+    I I+ HF+  L I  ++   S TL+I+ IP+ S   + +L HF EAYP+  + DIQFA+++ KLI L+  R+ A+HA+N ++ + A +G R  + P  CG    CC       ++D  +YY  E   L +   +E +KA  + +G+AFVTF +   A KV +D+  +    + P +S+LS   K   W++ +AP  + INW NL  P + W +++ LINS LFI LF LTTP   +N L +
Sbjct:   13 NFYSRAAEFSQSVGIIRADNDSHCNYYRPKNSSHLVIIPGGYEGIPQNLTINVIAWICLIILFSVLRKNAWNYGRMALLQRRERRETAPGYSEYNIWTQIFY--RREDRDGDSEGH------KAAPSFDPGSHYDHGMFSWILAVFRIKDDQIRSKCGDDAVQYLSFQRHIIVMMSITMVVSLAIALPINMQGD-LKGDEKQFGHTTLSNLDPKSWYLWIHVGLSILFVPIAIFIMRHFSKRLDIPEVDSTVSRTLMINHIPRSSCNKADLLKHFNEAYPEYEVIDIQFAYDLSKLIKLDRARQFALHARNYSVSE-AMSGNRMLVRPFLCGNVCVCCDPCCPKSKIDAAEYYTSEERQLASLVDQEKLKAIKRPVGIAFVTFASNLQAAKVRQDHRPNWRCGSNPGSSSLSVMFKPHRWSVDFAPRPDEINWGNLAIPSRFWYLRSFLINSFLFIVLFFLTTPAVVVNTLDI 475          

Query: 1457 MNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAF 2116
            M+ VL++FLP+ ++W  S L+P +V YS+  + HWTK+  +  ++ KT+ FL+ MV+ILPSLG+ S  +F  W             + W C+F P N AFFVNY+IT++FIGT  EL+R  EL +Y       +S  E+ G+R+N++WEF FG+ Y+W L  F++   YS  CPLI PFG +Y++ K+ VDRYNI+FAY  S IN  IH  A++F + AF
Sbjct:  488 MSPVLSQFLPTLLLWTTSALMPVMVAYSDEWMSHWTKSTANHTIMRKTFIFLMFMVVILPSLGLTSAQAFFEWATRSNGT------YRWECVFLPDNGAFFVNYVITSSFIGTALELMRFSELFMYACKLSCAKSRAEVPGVRRNLLWEFNFGVQYAWTLLNFSLITMYSVSCPLITPFGFVYVLLKHFVDRYNIFFAYAPSRINKNIHTTAINFVMIAF 701          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF      L+     + C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+   ++ RS+ E   ++K+  +EFQFG  Y+W++ VFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  482 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFD--KTFLDQAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAA 697          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTS--QFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F G+P    ++ + F+ L  +F  LRK AW++GR+AL++   R++Q            L E+        T  D + Y R  SV  +    Q D GF SWL   + + D +IREK G DA  YL FQ+++I    ++ V+S+ +ILPVN  G+        F  TTI NL + + ++W+H   +FLY    +  +    + +     +    TL I GI K +   S I  HF++AY  C + + +   ++ KL++L  +R     ++       A   +   + PK CG    CCI    E+ D ++YY +    L  + +KE  K   K + +AFVTF+       +L+D+++     C     P++S  S+ +++  WT+SYAP    + WE+L      W ++ ++IN  LFI LF LTTP   ++ +
Sbjct:   48 FGGVPTVLALDFMCFLGLLFVFSILRKVAWDYGRLALVSDADRQDQRYR--------RLDEREYVASAMQTPVDAR-YERLTSVCSSVDFDQRDSGFCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGINKYAE-ESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKFYTDLMAKEHVSTMINPKPCGHL-CCCIIKGCEQEDAVNYYTNLEAKLREEYKKEREKVNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTM 468          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF    +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+   ++ RS+ E   ++K+  +EFQFG  Y+W++ VFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  469 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKTFLDQAKVRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAA 684          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F G+P    ++ + F+ L  +F  LRK AW++GR+AL++     +  S    +   V    +       S +FD++               D GF SWL   + + D +IREK G DA  YL FQ+++I    ++ V+S+ +ILPVN  G+        F  TTI NL + + ++W+H   +FLY    +  +    + +     +    TL I GI K +   S I  HF++AY  C + + +   ++ KL++L  +R     ++       A   +   + PK CG    CCI    E+ D ++YY +    L  + +KE  K   K + +AFVTF+       +L+D+++     C     P++S  S+ +++  WT+SYAP    + WE+L      W ++ ++IN  LFI LF LTTP   ++ +
Sbjct:   48 FGGVPTVLALDFMCFLGLLFVFSILRKVAWDYGRLALVS-----DADSVASAMQTPVDARYERLTSVCSSVDFDQR---------------DSGFCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGINKYAE-ESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKFYTDLMAKEHVSTMINPKPCGHL-CCCIIKGCEQEDAVNYYTNLEAKLREEYKKEREKVNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTM 455          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF      L+     + C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+   ++ RS+ E   ++K+  +EFQFG  Y+W++ VFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  401 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFD--KTFLDQAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAA 616          

Query:  384 EKTYLRRASVIDTTS--QFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            +  Y R  SV  +    Q D GF SWL   + + D +IREK G DA  YL FQ+++I    ++ V+S+ +ILPVN  G+        F  TTI NL + + ++W+H   +FLY    +  +    + +     +    TL I GI K +   S I  HF++AY  C + + +   ++ KL++L  +R     ++       A   +   + PK CG    CCI    E+ D ++YY +    L  + +KE  K   K + +AFVTF+       +L+D+++     C     P++S  S+ +++  WT+SYAP    + WE+L      W ++ ++IN  LFI LF LTTP   ++ +
Sbjct:   32 DARYERLTSVCSSVDFDQRDSGFCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGINKYAE-ESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKFYTDLMAKEHVSTMINPKPCGHL-CCCIIKGCEQEDAVNYYTNLEAKLREEYKKEREKVNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTM 387          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W  S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG++SL  F  WLF    +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+   ++ RS+ E   ++K+  +EFQFG  Y+W++ VFTV +TYS  CP+IVPFGL+Y++ K+ VDRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  426 NPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKTFLDQAKVRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAA 641          

Query:  480 DKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            D +IREK G DA  YL FQ+++I    ++ V+S+ +ILPVN  G+        F  TTI NL + + ++W+H   +FLY    +  +    + +     +    TL I GI K +   S I  HF++AY  C + + +   ++ KL++L  +R     ++       A   +   + PK CG    CCI    E+ D ++YY +    L  + +KE  K   K + +AFVTF+       +L+D+++     C     P++S  S+ +++  WT+SYAP    + WE+L      W ++ ++IN  LFI LF LTTP   ++ +
Sbjct:   91 DDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGINKYAE-ESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKFYTDLMAKEHVSTMINPKPCGHL-CCCIIKGCEQEDAVNYYTNLEAKLREEYKKEREKVNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTM 412          

Query: 1439 SIKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNV 1894
            S+ +   + ++ +FLP+ ++WA S +LPF+VYYS  +  HWT++ E+   + K Y +LI MVLILPSLG+ SL  F  WLF    ++  +  F   C+F P N AFFVNY+IT+AFIGT  EL+R+P L++Y       RS  E    RKNV
Sbjct:  176 SLNRGPQSPIVTQFLPTLLLWAFSAVLPFLVYYSVFLESHWTRSTENRTTMHKCYFYLIFMVLILPSLGLTSLNVFFRWLFDKDFLEQGSVRFE--CVFLPDNGAFFVNYVITSAFIGTAMELLRVPGLLLYALRLCWARSKAE----RKNV 321          

Query:  963 EAIRQYANTGIRRTMVPKFCGRFHSCCI----EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            +A++ Y       T+ P+ CG    C      +EV+ +++Y      L A+C+KE  K   + +G+AFVTF+       +L DY+        P  S LS ++ ++ W + YAP  N I WENL      W  +  ++N++LF+ LF LTTP   +N +
Sbjct:    8 KALKYYDVRPEGETIDPRPCGHLCCCKCCGNHQEVNAVEHYRGLKNSLSAECEKERSKVRSQPLGMAFVTFQDDRMTSDILADYN-LLRCWRRPHVSRLSEELGASSWRVRYAPDPNSIIWENLQVQGLMWWCRVFVLNALLFLLLFFLTTPAIIVNTM 165          

Query:  777 NEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIE-----EVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYH----SSCS-------------LLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
             + S TL I GIPK      I+  HF EAYP C I D+QF +N+ KLI L+ +R+ A  A     R Y +     TM PK  G    CC +     +V+ +++Y      L  +C++E  K  D  +G+AFVTF   + A + L          C+              L  P+TS+  + ++S +W + YAP  N I WENL      W +K I++N+ LFI LF  +TP+  +N +
Sbjct:    9 GQVSRTLFIIGIPKHLDKEDILKSHFYEAYPSCTITDVQFCYNVEKLIKLDKERKKAAKA-----RAYYDNMTDETMRPKMYGEL--CCCDCYGYRKVNALEFYTALESRLTDECEEEKRKIPDNPLGMAFVTFHDDKSATQNLTTESLAIVVGCAKLPALEVPGIWRGCLGSPKTSSFGDMLRSKHWGVKYAPDPNSIIWENLTVQGFSWWVKVIVLNTFLFILLFFFSTPSIVVNTI 240          

Query: 1466 VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVI 1591
            ++ +FLP+ ++W  S+LLP +VYYS  +  HWT++ E+ A +
Sbjct:  256 IITQFLPTLLLWTFSSLLPLLVYYSVFLEAHWTRSSENRATM 297          

Query: 1727 CIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDR 2032
            C+F P N AFFVNY++TAA +G+ + L+R+PEL +Y     + RS      +RK   +EF +GL Y+W +C+ TVT++YS  CP+I PF L+Y     S  R
Sbjct:    4 CVFLPDNGAFFVNYVVTAALLGSAARLLRLPELALYGLRLCLARSDAHRHHVRKRCCYEFPYGLEYAWTMCIITVTMSYSVTCPIITPFVLLYSKLTLSARR 105          

Query: 1415 VKCVAVEFSIK-KISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYER---SFINSKIHRLAMSFT 2104
            +K   VE + K +++ N    +FLP+ ++W  S +LP +V YS     HWT++    +V+IKTY FL++MV++LPSL + S     + LF +             C+F P N AFFVNY++T+A IGT  EL R PEL  Y       +   E   +R+  + EF FG  Y+W++ +F+V V YS  CPL+ PFGL+Y+ FK+ VDRYN+YF Y      +++  +H  A+ FT
Sbjct:  386 IKASIVEKNPKLRVAPNPFFTQFLPTIMLWTFSAILPVVVSYSSYFEAHWTRSRLEHSVMIKTYVFLLLMVIVLPSLALTS----ADALFQVTLSGSALLKSRLACVFLPNNGAFFVNYLVTSALIGTALELCRFPELAAYAVRMCFAKDEGEKRLVRRESVREFAFGHQYAWMIVIFSVMVVYSIACPLVTPFGLLYLTFKHVVDRYNLYFNYRSPAYKYVDPSVHSTAVVFT 615          

Query:  216 FVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIR-RTMV--PKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPT 1409
             VLFC +R+  W++GR+A+ T+      +S  Y +   V  + K++ E+  S  F E                DKG  SW+     V+D+ I  K G DA QY+ FQK+LI  + II  +S+ ++LP+N  G   + + N F  TT+ NL + S M W+HAV + LY   I+ I+ HF +   + +++E++ T++I  IPK  +   +I  HF E Y    I+++Q A+N  KL  +  + E A   +          G R +T V   K       C ++ VD I+Y+ +  +  +A+ + E  K   K +GVAFVTF   E ++K L+D++   ++ +    S++S  I S +W ++ AP +  I WE+L    + W  +A++IN ILFIF+  +TTPT
Sbjct:    1 MVLFCVIRRLVWDYGRLAV-TQKEDLGWTSVFYGL--NVNGNGKDKQEDKPSVTFPEVK--------------DKGLLSWVPVLLRVTDEHIHVKCGMDALQYIQFQKHLIVYSVIIFCLSIGIVLPINYSGTN-EYERNSFGATTVSNLEAQSSMFWLHAVFALLYIIIIVVILRHFTSLFNMESLHESATTVMITNIPKNVT-KELIQQHFVEVYDDSMIEEVQLAYNCDKLQSIERKLEAARLGREHCQELLQLNGERPQTTVSTSKVSPCMMCCGVKHVDGIEYFTE--VEGKARVEFEQTKQSLKSLGVAFVTFVNEETSQKCLKDFN---TIKHGSPESSVSRKIFSDHWNVASAPLTGDILWEHLSVDPESWWARALIINIILFIFVLFITTPT 377          

Query:  420 TTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIW------------HFATTLQ---ITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDA 1181
            T  +++  FF WL       D  I E+ G DA  Y+ F K  I  + ++    ++V++P+N++G G +   +     T+ NL+  +   W H +  + Y   I  +++            H A  L       + E S  LL             IL  + EA     + +     N++K + L  + + A+ +  +A  Q    G R    PK       CC E+ D I ++ + + +++ + + E+ +     I  AF+ F++++ A
Sbjct:   59 TPQKYNNSFFGWLLLSKAADDDTIFEEAGIDALVYMRFIKLCIKISIVLLPYGIVVLIPLNVYG-GLEKPLSGLDVLTMSNLAEKASKGWAHLIAVWGYTLIICYLLYQEWGVYISYRQKHLAVGLPNQYAVFVRELSPKLLDKS----------ILSKYMEALFPGQVSEAIIVQNLKKWVALIGKHDAAVLSLEKARHQLLTKGDRPQHRPK-------CCGEKTDSITFHENNLKVMQGRLEDEL-RCDHPSIPCAFIVFKSLQSA 308          

Query: 1466 VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            V+ +FLP+ ++WA S LLPFIVYYS     HWT++ ++   + K +  L+ MV+ILPSLG++SL  F  WLF +  ++     F   C+F P N AFFVNY+IT++ IGT  EL+RIP L +Y +     +S  E   ++K+  +EFQFGL Y+W +C+F V++TYS  CP+I PFGL+Y I K+ VDRYNIY+AY  + +N +IHR A S  + A
Sbjct:  472 VITQFLPTLLLWAFSVLLPFIVYYSAFFESHWTRSGQNQVTMHKCFLLLVFMVIILPSLGLSSLDLFFTWLFDVNFLEEKEVKFQ--CVFLPDNGAFFVNYVITSSLIGTSMELLRIPALTVYAFRLCFAKSQAERIHVKKSQAYEFQFGLEYAWTMCIFAVSMTYSITCPIITPFGLLYAILKHMVDRYNIYYAYIPTKLNQRIHRAATSQVIVA 685          

Query:  138 NDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVP-KFCGRFHSCCI---EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            + ++V+ G  F G+P    IN+V ++ L ++F  LRK AW++GR+ALL +N          +   ++   E +E E+T S            S  D+ ++ D GF SWL   Y + D +IR K G DA  YL FQ+++I    +++++SL VILPVN  GN       +F  TT+ N+S+    +W+H++ + +YF   +  + H A  L+     + + TL+I  IP+E     +I  HF EAYP C + D +F  ++ KLI L+L+R  A+  +     +    G  + M+    C     C I   E VD   YY++       +   E  +   K++G+AFVTF        +++DY S       PQ S+++  ++S  W +SYAP  + I WENL     +W ++ +L+N +LF+ LF LTTP   +N +
Sbjct:   45 SRSSVLQGLPFGGVPTVLAINVVLWMFLLLIFSCLRKAAWDYGRLALLMEN----------DSLTSLFYGEPSEKEKTPS----------ETSPSDSDTK-DMGFCSWLLSLYYMKDGEIRSKCGIDAVTYLSFQRHIILLMTVVSLLSLAVILPVNFSGNLLGDSPQNFGRTTLANVSAKDNFLWLHSIFALVYFIITMLCMAHHAIRLEYREDEKVARTLMITSIPREICDPGLITKHFHEAYPSCTVTDNRFCFDVHKLIKLDLERRKAMKGRLYFTTKAQKEG--KIMIKTHLCAHIFGCDICGFERVDAEQYYSELEEKRTDEFNAEKSRISLKRLGIAFVTFRDERMTAVIVKDY-SRVRCRRRPQQSSITTVVQSHKWGVSYAPAPSDIIWENLSVCGSRWWLRCVLLNILLFLLLFFLTTPAIIVNTM 456          

Query: 1466 VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            V+ +FLP+ ++WA S LLPFIVYYS     HWT++ ++   + K +  L+ MV+ILPSLG++SL  F  WLF +  ++     F   C+F P N AFFVNY+IT++ IGT  EL+RIP L +Y +     +S  E   ++K+  +EFQFGL Y+W +C+F V++TYS  CP+I PFGL+Y I K+ VDRYNIY+AY  + +N +IHR A S  + A
Sbjct:  472 VITQFLPTLLLWAFSVLLPFIVYYSAFFESHWTRSGQNQVTMHKCFLLLVFMVIILPSLGLSSLDLFFTWLFDVNFLEEKEVKFQ--CVFLPDNGAFFVNYVITSSLIGTSMELLRIPALTVYAFRLCFAKSQAERIHVKKSQAYEFQFGLEYAWTMCIFAVSMTYSITCPIITPFGLLYAILKHMVDRYNIYYAYIPTKLNQRIHRAATSQVIVA 685          

Query:  138 NDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVP-KFCGRFHSCCI---EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            + ++V+ G  F G+P    IN+V ++ L ++F  LRK AW++GR+ALL +N          +   ++   E +E E+T S            S  D+ ++ D GF SWL   Y + D +IR K G DA  YL FQ+++I    +++++SL VILPVN  GN       +F  TT+ N+S+    +W+H++ + +YF   +  + H A  L+     + + TL+I  IP+E     +I  HF EAYP C + D +F  ++ KLI L+L+R  A+  +     +    G  + M+    C     C I   E VD   YY++       +   E  +   K++G+AFVTF        +++DY S       PQ S+++  ++S  W +SYAP  + I WENL     +W ++ +L+N +LF+ LF LTTP   +N +
Sbjct:   45 SRSSVLQGLPFGGVPTVLAINVVLWMFLLLIFSCLRKAAWDYGRLALLMEN----------DSLTSLFYGEPSEKEKTPS----------ETSPSDSDTK-DMGFCSWLLSLYYMKDGEIRSKCGIDAVTYLSFQRHIILLMTVVSLLSLAVILPVNFSGNLLGDSPQNFGRTTLANVSAKDNFLWLHSIFALVYFIITMLCMAHHAIRLEYREDEKVARTLMITSIPREICDPGLITKHFHEAYPSCTVTDNRFCFDVHKLIKLDLERRKAMKGRLYFTTKAQKEG--KIMIKTHLCAHIFGCDICGFERVDAEQYYSELEEKRTDEFNAEKSRISLKRLGIAFVTFRDERMTAVIVKDY-SRVRCRRRPQQSSITTVVQSHKWGVSYAPAPSDIIWENLSVCGSRWWLRCVLLNILLFLLLFFLTTPAIIVNTM 456          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W+ S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG+ SL  F  WLF  + +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+    + RS+ +   ++++  +EFQFG  Y+W++CVFTV +TYS  CP+IVPFGL+Y++ K+  DRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  487 NPIVTQFFPTLLLWSFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLTSLDVFFRWLFDKKFLADAKVRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAADRRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLADRYNMYYAYLPSKLDKKIHSGAVNQVVAA 702          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTS--QFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI---EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F G+P    ++ + F+ L  LF  LRK AW++GR+AL+ K+  +      Y   +         +E +D        Y R ASV  +    Q D GF SWL   + + + ++REK G DA  YL FQ+++I    ++ V+S+ +ILPVN  GN  +     F  TTI NL   ++++W+H   +FLY    +  +    + +     +    TL I+GI K+     I   HF+ AY  C + + +  +++ KL+ LN +R+ A  ++   I    N      + PK CG    C I   E+ + + YY +    +  Q + E  K   K +G+AFVTF+       +L+D+++     C     P+ S  S  +++  WT+ YAP    + WE+L     KW ++ +LIN ILF+ LF LTTP   ++ +
Sbjct:   51 FGGVPTVLALDFMCFLGLLFLFSILRKLAWDYGRLALIAKDDSERSMDQRYCRLDGREYMSAVTSETSDR-------YERLASVSSSLDFDQTDHGFCSWLTAVFRIKEDELREKCGEDAIHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGNLLENNAYSFGRTTIANLDVGNKLLWLHTTFAFLYLLLTVFSMRRHTSKMHYKENDLVKRTLFINGISKQGEEREIK-QHFESAYSNCTVLETRICYDVAKLMQLNSERKKAERSKKYFIDLDKNASEPSKVNPKPCGHLCCCAIKGCEQENAVSYYTNLEAEIRQQYRTEREKVNKKPLGMAFVTFQNETITATILKDFNACKCQGCHCRREPRRSNHSKTLQTHNWTVMYAPHPQNVYWEHLSVGGAKWWLRCLLINCILFLLLFFLTTPAIIISTM 473          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            N ++ +F P+ ++W+ S LLP IVYYS     HWT++ E+   + K YTFLI MVL+LPSLG+ SL  F  WLF  + +      F   C+F P N AFFVNY+I +AFIG   +L+RIP L++Y+    + RS+ +   ++++  +EFQFG  Y+W++CVFTV +TYS  CP+IVPFGL+Y++ K+  DRYN+Y+AY  S ++ KIH  A++  V A
Sbjct:  473 NPIVTQFFPTLLLWSFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLTSLDVFFRWLFDKKFLADAKVRFE--CVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAADRRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLADRYNMYYAYLPSKLDKKIHSGAVNQVVAA 688          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCI---EEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVL 1427
            F G+P    ++ + F+ L  LF  LRK AW++GR+AL+ K+  +  S+       T   S++ E   + S+  D               Q D GF SWL   + + + ++REK G DA  YL FQ+++I    ++ V+S+ +ILPVN  GN  +     F  TTI NL   ++++W+H   +FLY    +  +    + +     +    TL I+GI K+     I   HF+ AY  C + + +  +++ KL+ LN +R+ A  ++   I    N      + PK CG    C I   E+ + + YY +    +  Q + E  K   K +G+AFVTF+       +L+D+++     C     P+ S  S  +++  WT+ YAP    + WE+L     KW ++ +LIN ILF+ LF LTTP   ++ +
Sbjct:   51 FGGVPTVLALDFMCFLGLLFLFSILRKLAWDYGRLALIAKDDSESMSAV------TSETSDRYERLASVSSSLD-------------FDQTDHGFCSWLTAVFRIKEDELREKCGEDAIHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGNLLENNAYSFGRTTIANLDVGNKLLWLHTTFAFLYLLLTVFSMRRHTSKMHYKENDLVKRTLFINGISKQGEEREIK-QHFESAYSNCTVLETRICYDVAKLMQLNSERKKAERSKKYFIDLDKNASEPSKVNPKPCGHLCCCAIKGCEQENAVSYYTNLEAEIRQQYRTEREKVNKKPLGMAFVTFQNETITATILKDFNACKCQGCHCRREPRRSNHSKTLQTHNWTVMYAPHPQNVYWEHLSVGGAKWWLRCLLINCILFLLLFFLTTPAIIISTM 459          

Query:  135 TNDTAVIYG--FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQF--DKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIE---EVDVIDYY--NDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHS-----SCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIK 1352
            TN + V+ G  F GIP    ++   FI+L VLF  +R+  W++GR+AL++        S G+N                   E   + Y R +S    T  F  + GF SWL +   + ++ I+EK G DA  YL FQ++LI    +ITV SL +I+PVNM G+  K    +F  TTI NL + + ++W+H V + +Y    + ++    + ++      A NTL +  +PK ++    +  HF EAYP C +  +   +++ +L+HL+ +R  A        R    TG R  + P+ CG  H CC     +VD I+YY   ++ L+ E + + EIV  +   +G+AFVT +    A+ +L+D+++     S      PQ S+ S  +K   W +S+AP    + WENL      W ++
Sbjct:   29 TNQSTVLSGLNFGGIPLVLLLDFCVFIVLLVLFSIIREKFWDYGRLALVS-------DSDGFN-------------------ESTHRRYGRMSSAASNTEDFGYESGFCSWLPYIVRMDEEKIKEKCGIDAVHYLSFQRHLIILLVVITVTSLAIIMPVNMSGDLLKNDPQNFGRTTIGNLKTGNNLLWLHTVFAVIYLALTVVMLRVHTSQMKGLRKETARNTLFVSPVPKTAT-EEDVKAHFVEAYPTCEVCAVTLGYDVARLMHLDKERLRAGKNLRYYERVLDKTGQRELINPRLCG--HICCCSGCVKVDAIEYYCGKEKFLLEEVRQEAEIVPQH--TLGIAFVTLKNEAMAKYILKDFNAIECRGSTCCGREPQPSSQSRALKVNKWRVSFAPHPKSVYWENLSVRGFTWAVR 417          

Query: 1466 VLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFA 2113
            ++ +F P+ ++W+ S LLP IVYYS +   HW+++ E  +++ K Y FL+ MVLILPSLG+ SL  F  WLF  + + L    F   C+F P   AFFVNY+I A  +G+  +L+R+P L++YL   ++ RS+ E   +++N  +EF++G  Y W LCVFTV + YS ICP+IVPFGL+Y++ K+ VDR+N+YFAY  + ++ ++H  A+   + A
Sbjct:  458 IITQFFPTLLLWSFSALLPTIVYYSTLGEAHWSRSSEQLSMMRKLYFFLLFMVLILPSLGLTSLAVFFRWLFDKEFLNLGKLRFE--CVFLPDQGAFFVNYVIAAGLVGSGMDLLRLPGLLLYLIRMMLARSAAERKYVKQNQAYEFEYGAMYGWTLCVFTVIMAYSIICPIIVPFGLLYMLLKHLVDRHNLYFAYLPTRLDHQVHMGAVDQALAA 671          

Query:   87 MSKATPVCDRVNIYRITNDTAVIYGFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVLQLNFQSKK 1451
            MSKATPVCDRVNIYRITNDTAVIYGFEGIPQNFTINIVT IILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAILINSILFIFLFMLTTPTYALNVLQLNFQSKK
Sbjct:    1 MSKATPVCDRVNIYRITNDTAVIYGFEGIPQNFTINIVTSIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFHSCCIEEVDVIDYYNDEILILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLEDYHSSCSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAILINSILFIFLFMLTTPTYALNVLQLNFQSKK 455          

Query: 1424 VAVEFSIKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFXXXXXXXXXXXXVNKVKSNLVYIFVXXXXXXXXXXXXXXXXYGWFTQVKTKVTNEENFGQIVLPTTPLMPSLMATLNLIPSAKNRP 2374
            + + F  KKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFLLLQINLLIYLNVNKVKSNLVYIFVFISCILSLTLF+FFTFYGWFTQVKTKVTNEENFGQIVLPTTPLMPSLMATLNLIPSAKNRP
Sbjct:  447 LQLNFQSKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFLLLQINLLIYLNVNKVKSNLVYIFVFISCILSLTLFMFFTFYGWFTQVKTKVTNEENFGQIVLPTTPLMPSLMATLNLIPSAKNRP 763          

Query: 1460 NIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSF 2101
            N ++ +F PS +M  VS ++P IVY+S+ +  HWTKT ++ AV+ K +T L+I VLILPSLG+ S+P  I WLF   +   NT    W CIF     A F NYIITA+FIGT  EL+R+ EL +Y   +   RS  E   I K+V+W+FQFG+ Y+W L +F+V   YS I P+I PFGL Y++ K+ VDRYN+      S +++ +H  A   
Sbjct:  460 NPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFTVLVITVLILPSLGLNSVPELIKWLFITNSTAPNTI--KWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQL 671          

Query:   99 TPVCDRVNIY--RITNDTAVIYGFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRF---HSCC----IEEVDVIDYYNDEILILEAQCQKEIVKAYD-KKIGVAFVTFETIEDARKVLEDYHSS---CSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNV 1424
            TP CDR N Y  R  N   +   +EGIPQN  IN+V + I+  LF FLRK AWN+G +A L K    E  +             K    E     F +   +     I+ T  F +   + L  F  ++D+ ++++ G+DA  Y  FQ+ LI    ++ V+SL +I+P+N+ G+      + F++ TI N+   S  +W+H  +S  +   +  I       +      E S T++I+ +P E     II  HF+EAYP      +Q  + +  LI L  Q+  A  A      +  +   R  ++P  CGR      CC       +D I++Y  E++ L      E   A + KK+ + FVTFE ++ A +V  DY      C   +    S+ S+ + S  WT+++AP    I W+NL     +W +  I+IN  + I + +L+TP  ALN+
Sbjct:    4 TPQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTIIISLFLFLRKKAWNYGNLAWLGKPLNIEHVA-----------PRKESRSEHSEAIFSDTDPIASKENINLT--FKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPLNLRGSFLSSNSSMFSSLTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKHGWRWWLPIIVINMFVGIVIIILSTPAVALNI 445          

Query:  108 CDRVNIYRITNDTAVIYGFEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRF---HSCC---IEEVDVIDYYNDEI---LILEAQCQKEIVKAYDKKIGVAFVTFETIEDARKVLED--YHSSCSLLNYPQT-SALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVLQLNFQSK 1448
            CDR N Y+ TN + +   +EGIP N  IN++ ++IL  +F  LRK AWN+G IA  TK              N ++L+ KN    T S + +E    R   + ++ ++F   F+  L  F  +SD+D+ ++ G DA  Y  FQ+ L+  + ++ V  L++I+P+N+ G+      + F T TI N+ + S+++ VH +++FL    +  I   F   +      + S +L+I  +P E+   S+I  HF+E YP+     +Q A+ +  +I+L + + +A  A    + +  +   R  + P   GR      CC    + +D I+YY  E+     L  + QK+ +K  +KK+ + FV+F++IE A  +  +  Y + C +  YP++ S+LS  + S  W + +AP S  I WENL     K  +K ILINS + + +  L+TP+  +     NFQS+
Sbjct:    3 CDRYNSYK-TNVSFIPNSYEGIPLNLLINVIVYLILIGVFLILRKRAWNYGDIAWFTKP------------INIMSLALKNRLSVTSSDKTEEHEE-REKLMENSKNRFIDRFWKALPLFIKISDQDLEKRCGCDAVIYCKFQRMLLLISTVMVVAGLIIIVPLNLSGHSLSKDTSSFKTLTIANIGTGSKVLSVHLIVAFLLMIFVFFISNKFLKYVDDHGKEKVSYSLMITRVPLEACDESLIEQHFREIYPEISNMKVQRAYEIECMINLYISKVLAEEALEYCVDELEHFNRRVKVAPNVFGRMCIACKCCEAICKPIDGIEYYMKEVKRTTELFNEEQKKTLK--EKKLPIFFVSFDSIEHALLIRREYIYQNYCCIKPYPKSQSSLSKILNSDNWKVIFAPISKDILWENLHKKGWKLWVKIILINSFVALLVITLSTPSMIIKFWNDNFQSQ 445          

Query: 1472 NRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIH 2083
            ++F PS +M  V+  +P ++  S  +  H T+T +  A++ K +T L + VLILPSLG+ S    +  +F+  N  + T  F W CIF     A F NY+I+A FIG   E++RI  L +++      +S  E  GI ++++WEF +G+ Y+W L +F++   YS I PLI PFGL+Y++ K+ VDRYN+   +  + I S +H
Sbjct:  455 SQFFPSIVMVLVTATMPLLICLSNEISAHQTRTKQSIAIMNKLFTVLTVTVLILPSLGLNSAQELMLQIFNRTNASIFTI-FKWDCIFLYDGGALFCNYLISAGFIGMGLEILRIGPLFLFMIKMSTAKSEAENNGIAQSLLWEFPYGINYAWTLALFSIISAYSVIVPLITPFGLVYLVSKHMVDRYNMVHVFIPAVIESSVH 657          

Query: 1469 LNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIH 2083
            +++F PS IM  V++++P +V ++  M  HWT+T ++ A++ K +  L++ VL LPSLG++S    + W F  +N   N   F W C+F     + F NY+I+A FIG   E++R+ +L++ ++     RS  E  GI +++ WEF +G+ Y+W L +F++  TY+ I PLI PFGL Y+I KY VDRY++      + +++ +H
Sbjct:  447 ISQFFPSLIMVIVTSIMPVLVCWANDMSAHWTRTKQNIAIMNKLFAVLVLTVLFLPSLGLSSAHELL-WSFFNKNETFNKI-FKWECLFLADGGSIFCNYLISAGFIGMGLEILRLGQLLLIIFKLSWSRSKAEERGIVQSLSWEFPYGINYAWTLALFSIISTYAVIVPLITPFGLFYLISKYLVDRYSMIHVNIPALVDNDVH 649          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTK--NRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRF---HSCCI---EEVDVIDYYNDEILILEAQCQKEIVKAYDK-KIGVAFVTFETIEDARKVLED--YHSSCSLLNYPQT-SALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAXXXXXXXXXXXXXXTTPTYALNVLQLNFQSK 1448
            +EGIP N  IN+V +I+L ++F  LRKNAWN+G I  LTK  N  +E +            S     E+   +  D    L+              F  W+  F  +SDK +R++ G DA  Y MFQ+ LI  + ++TV+ L +ILP+N  G+      + F T TI N+   S  +  H  +SF+    +  I   F   +      +   TL+I  IP E     +I  HFKEAYP      +Q  + + KL  L   + +A  A    + QY     R  +     GR     +CC+   + +D I YY +E+        KE    +D  K+ + FV+F++IE A  +  +  Y + C +  YP++ S+LS  +KS  W + +AP    I WENL      + +K I IN  +   +  L+TP   L +    FQ K
Sbjct:   20 YEGIPFNILINVVVYILLILIFLMLRKNAWNYGVIEWLTKPVNVMEEAADQ----------SGLTSPEDCVESNGDNNRALQ-----------SNIFCRWIPLFIRMSDKCLRKRCGFDAVIYCMFQRMLILISSVMTVLCLTIILPLNFSGSLLSDDSSSFKTLTIANIEVGSTKLAFHLSISFILMIFVFFISNWFLKFVDTKIHKKTGVTLMITNIPIEVYDEQLIEQHFKEAYPTISNMKVQKTYAIGKLFDLYTNKVLAEEALEYCVTQYERFDRRVKVASNAFGRMCVSCNCCVAKCQPIDGIGYYTEEVKRCTELFYKEQKLTFDSGKLPIVFVSFDSIEHAVVIRREYIYQNYCCIKQYPKSQSSLSMRLKSDNWKVIFAPIPKDILWENLHKQGLVFWLKIIFINLFVAFIVITLSTPPIILQIWNKFFQDK 439          

Query:  162 FEGIPQNFTINIVTFIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRF---HSCCI---EEVDVIDYYNDEILILEAQCQKEIVKAYDK-KIGVAFVTFETIEDARKVLED--YHSSCSLLNYPQT-SALSNDIKSAYWTISYAPPSNVINW 1313
            +EGIP N  IN+V +I+L ++F  LRKNAWN+G I  LTK                V + E    E  D +          ++  +  +     F  W+  F  +SDK +R++ G DA  Y MFQ+ LI  + ++TV+ L +ILP+N  G+      + F T TI N+   S  +  H  +SF+    +  I   F   +      +   TL+I  IP E     +I  HFKEAYP      +Q  + + KL  L   + +A  A    + QY     R  +     GR     +CC+   + +D I YY +E+        KE    +D  K+ + FV+F++IE A  +  +  Y + C +  YP++ S+LS  +KS  W + +AP    I W
Sbjct:   20 YEGIPFNILINVVVYILLILIFLMLRKNAWNYGVIEWLTK---------------PVNVME----EAADQSGLTSPEDCVESNGDNNRALQSNIFCRWIPLFIRMSDKCLRKRCGFDAVIYCMFQRMLILISSVMTVLCLTIILPLNFSGSLLSDDSSSFKTLTIANIEVGSTKLAFHLSISFILMIFVFFISNWFLKFVDTKIHKKTGVTLMITNIPIEVYDEQLIEQHFKEAYPTISNMKVQKTYAIGKLFDLYTNKVLAEEALEYCVTQYERFDRRVKVASNAFGRMCVSCNCCVAKCQPIDGIGYYTEEVKRCTELFYKEQKLTFDSGKLPIVFVSFDSIEHAVVIRREYIYQNYCCIKQYPKSQSSLSMRLKSDNWKVIFAPIPKDILW 394